LOCUS       DAYNVV010000001       160276 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.001, whole genome shotgun sequence.
ACCESSION   DAYNVV010000001 DAYNVV010000000
VERSION     DAYNVV010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 160276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 160276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..160276
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.001"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(265..2451)
                     /locus_tag="ACGXWR_000001"
     CDS             complement(265..2451)
                     /locus_tag="ACGXWR_000001"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HFK0801625.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            2669..3352
                     /locus_tag="ACGXWR_000002"
     CDS             2669..3352
                     /locus_tag="ACGXWR_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HFK0801626.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            complement(3433..4152)
                     /locus_tag="ACGXWR_000003"
     CDS             complement(3433..4152)
                     /locus_tag="ACGXWR_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFK0801627.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(4464..4670)
                     /locus_tag="ACGXWR_000004"
     CDS             complement(4464..4670)
                     /locus_tag="ACGXWR_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801628.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            4915..5517
                     /locus_tag="ACGXWR_000005"
     CDS             4915..5517
                     /locus_tag="ACGXWR_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFK0801629.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            5658..6938
                     /locus_tag="ACGXWR_000006"
     CDS             5658..6938
                     /locus_tag="ACGXWR_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFK0801630.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            6951..7679
                     /locus_tag="ACGXWR_000007"
     CDS             6951..7679
                     /locus_tag="ACGXWR_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFK0801631.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(7748..9271)
                     /locus_tag="ACGXWR_000008"
     CDS             complement(7748..9271)
                     /locus_tag="ACGXWR_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFK0801632.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKI
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            9523..10704
                     /locus_tag="ACGXWR_000009"
     CDS             9523..10704
                     /locus_tag="ACGXWR_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFK0801633.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(10764..12392)
                     /gene="treC"
                     /locus_tag="ACGXWR_000010"
     CDS             complement(10764..12392)
                     /gene="treC"
                     /locus_tag="ACGXWR_000010"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HFK0801634.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(12843..15554)
                     /locus_tag="ACGXWR_000011"
     CDS             complement(12843..15554)
                     /locus_tag="ACGXWR_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFK0801635.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(15564..16265)
                     /locus_tag="ACGXWR_000012"
     CDS             complement(15564..16265)
                     /locus_tag="ACGXWR_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0801636.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            16451..17050
                     /locus_tag="ACGXWR_000013"
     CDS             16451..17050
                     /locus_tag="ACGXWR_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFK0801637.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            17131..18144
                     /locus_tag="ACGXWR_000014"
     CDS             17131..18144
                     /locus_tag="ACGXWR_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFK0801638.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            18252..19169
                     /gene="rbsK"
                     /locus_tag="ACGXWR_000015"
     CDS             18252..19169
                     /gene="rbsK"
                     /locus_tag="ACGXWR_000015"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HFK0801639.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            19197..19592
                     /gene="rbsD"
                     /locus_tag="ACGXWR_000016"
     CDS             19197..19592
                     /gene="rbsD"
                     /locus_tag="ACGXWR_000016"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HFK0801640.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            19592..20965
                     /locus_tag="ACGXWR_000017"
     CDS             19592..20965
                     /locus_tag="ACGXWR_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFK0801641.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            21322..23466
                     /locus_tag="ACGXWR_000018"
     CDS             21322..23466
                     /locus_tag="ACGXWR_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFK0801642.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(23518..24558)
                     /locus_tag="ACGXWR_000019"
     CDS             complement(23518..24558)
                     /locus_tag="ACGXWR_000019"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFK0801643.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(24835..26637)
                     /locus_tag="ACGXWR_000020"
     CDS             complement(24835..26637)
                     /locus_tag="ACGXWR_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0801644.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(26651..27403)
                     /locus_tag="ACGXWR_000021"
     CDS             complement(26651..27403)
                     /locus_tag="ACGXWR_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0801645.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(27412..27774)
                     /locus_tag="ACGXWR_000022"
     CDS             complement(27412..27774)
                     /locus_tag="ACGXWR_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFK0801646.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(27950..28822)
                     /locus_tag="ACGXWR_000023"
     CDS             complement(27950..28822)
                     /locus_tag="ACGXWR_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFK0801647.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(28873..29361)
                     /locus_tag="ACGXWR_000024"
     CDS             complement(28873..29361)
                     /locus_tag="ACGXWR_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HFK0801648.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(29499..30290)
                     /locus_tag="ACGXWR_000025"
     CDS             complement(29499..30290)
                     /locus_tag="ACGXWR_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HFK0801649.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(30345..30953)
                     /locus_tag="ACGXWR_000026"
     CDS             complement(30345..30953)
                     /locus_tag="ACGXWR_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HFK0801650.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(30946..31263)
                     /locus_tag="ACGXWR_000027"
     CDS             complement(30946..31263)
                     /locus_tag="ACGXWR_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFK0801651.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(31419..32147)
                     /locus_tag="ACGXWR_000028"
     CDS             complement(31419..32147)
                     /locus_tag="ACGXWR_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HFK0801652.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            32306..33187
                     /locus_tag="ACGXWR_000029"
     CDS             32306..33187
                     /locus_tag="ACGXWR_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFK0801653.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(33424..34467)
                     /locus_tag="ACGXWR_000030"
     CDS             complement(33424..34467)
                     /locus_tag="ACGXWR_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFK0801654.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(34470..35138)
                     /locus_tag="ACGXWR_000031"
     CDS             complement(34470..35138)
                     /locus_tag="ACGXWR_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFK0801655.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            35280..37616
                     /locus_tag="ACGXWR_000032"
     CDS             35280..37616
                     /locus_tag="ACGXWR_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HFK0801656.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(37732..38043)
                     /locus_tag="ACGXWR_000033"
     CDS             complement(37732..38043)
                     /locus_tag="ACGXWR_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801657.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            38224..39699
                     /locus_tag="ACGXWR_000034"
     CDS             38224..39699
                     /locus_tag="ACGXWR_000034"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HFK0801658.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            39746..40330
                     /locus_tag="ACGXWR_000035"
     CDS             39746..40330
                     /locus_tag="ACGXWR_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HFK0801659.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            40332..40751
                     /locus_tag="ACGXWR_000036"
     CDS             40332..40751
                     /locus_tag="ACGXWR_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HFK0801660.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(41032..41316)
                     /locus_tag="ACGXWR_000037"
     CDS             complement(41032..41316)
                     /locus_tag="ACGXWR_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HFK0801661.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(41548..42258)
                     /locus_tag="ACGXWR_000038"
     CDS             complement(41548..42258)
                     /locus_tag="ACGXWR_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HFK0801662.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(42255..43727)
                     /locus_tag="ACGXWR_000039"
     CDS             complement(42255..43727)
                     /locus_tag="ACGXWR_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFK0801663.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            43865..44338
                     /locus_tag="ACGXWR_000040"
     CDS             43865..44338
                     /locus_tag="ACGXWR_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFK0801664.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(44491..45042)
                     /locus_tag="ACGXWR_000041"
     CDS             complement(44491..45042)
                     /locus_tag="ACGXWR_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFK0801665.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            45147..45677
                     /locus_tag="ACGXWR_000042"
     CDS             45147..45677
                     /locus_tag="ACGXWR_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HFK0801666.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(46160..46603)
                     /locus_tag="ACGXWR_000043"
     CDS             complement(46160..46603)
                     /locus_tag="ACGXWR_000043"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFK0801667.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(46619..47779)
                     /locus_tag="ACGXWR_000044"
     CDS             complement(46619..47779)
                     /locus_tag="ACGXWR_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFK0801668.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            48286..49986
                     /locus_tag="ACGXWR_000045"
     CDS             48286..49986
                     /locus_tag="ACGXWR_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801669.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLHA
                     "
     gene            complement(50088..50921)
                     /locus_tag="ACGXWR_000046"
     CDS             complement(50088..50921)
                     /locus_tag="ACGXWR_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFK0801670.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(51225..53390)
                     /locus_tag="ACGXWR_000047"
     CDS             complement(51225..53390)
                     /locus_tag="ACGXWR_000047"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HFK0801671.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            53650..55944
                     /locus_tag="ACGXWR_000048"
     CDS             53650..55944
                     /locus_tag="ACGXWR_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HFK0801672.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            55937..56602
                     /gene="pgmB"
                     /locus_tag="ACGXWR_000049"
     CDS             55937..56602
                     /gene="pgmB"
                     /locus_tag="ACGXWR_000049"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFK0801673.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            56595..57602
                     /locus_tag="ACGXWR_000050"
     CDS             56595..57602
                     /locus_tag="ACGXWR_000050"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFK0801674.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            57624..58643
                     /locus_tag="ACGXWR_000051"
     CDS             57624..58643
                     /locus_tag="ACGXWR_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFK0801675.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(58924..60291)
                     /gene="nhaC"
                     /locus_tag="ACGXWR_000052"
     CDS             complement(58924..60291)
                     /gene="nhaC"
                     /locus_tag="ACGXWR_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFK0801676.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(60400..61821)
                     /gene="tyrP"
                     /locus_tag="ACGXWR_000053"
     CDS             complement(60400..61821)
                     /gene="tyrP"
                     /locus_tag="ACGXWR_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070908 - tyrosine:tyramine antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-tyramine antiporter"
                     /protein_id="HFK0801677.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(62064..63941)
                     /gene="tdc"
                     /locus_tag="ACGXWR_000054"
     CDS             complement(62064..63941)
                     /gene="tdc"
                     /locus_tag="ACGXWR_000054"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFK0801678.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(64232..65488)
                     /gene="tyrS"
                     /locus_tag="ACGXWR_000055"
     CDS             complement(64232..65488)
                     /gene="tyrS"
                     /locus_tag="ACGXWR_000055"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HFK0801679.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(65600..65805)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            66068..67369
                     /locus_tag="ACGXWR_000056"
     CDS             66068..67369
                     /locus_tag="ACGXWR_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFK0801680.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(67438..68037)
                     /locus_tag="ACGXWR_000057"
     CDS             complement(67438..68037)
                     /locus_tag="ACGXWR_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFK0801681.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            68292..69173
                     /locus_tag="ACGXWR_000058"
     CDS             68292..69173
                     /locus_tag="ACGXWR_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFK0801682.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            69186..70796
                     /locus_tag="ACGXWR_000059"
     CDS             69186..70796
                     /locus_tag="ACGXWR_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0801683.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAKGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(70873..71532)
                     /locus_tag="ACGXWR_000060"
     CDS             complement(70873..71532)
                     /locus_tag="ACGXWR_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFK0801684.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(71815..72480)
                     /locus_tag="ACGXWR_000061"
     CDS             complement(71815..72480)
                     /locus_tag="ACGXWR_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HFK0801685.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(72627..73232)
                     /gene="dhaL"
                     /locus_tag="ACGXWR_000062"
     CDS             complement(72627..73232)
                     /gene="dhaL"
                     /locus_tag="ACGXWR_000062"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HFK0801686.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(73260..74270)
                     /gene="dhaK"
                     /locus_tag="ACGXWR_000063"
     CDS             complement(73260..74270)
                     /gene="dhaK"
                     /locus_tag="ACGXWR_000063"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HFK0801687.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(74245..74640)
                     /gene="dhaM"
                     /locus_tag="ACGXWR_000064"
     CDS             complement(74245..74640)
                     /gene="dhaM"
                     /locus_tag="ACGXWR_000064"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HFK0801688.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            74794..75114
                     /locus_tag="ACGXWR_000065"
     CDS             74794..75114
                     /locus_tag="ACGXWR_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HFK0801689.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(75226..76083)
                     /locus_tag="ACGXWR_000066"
     CDS             complement(75226..76083)
                     /locus_tag="ACGXWR_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFK0801690.1"
                     /translation="MKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTISSSG
                     AENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELEEALE
                     AAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQQAKE
                     FNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAASFQRI
                     KDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGVLVAA
                     AYGIIRKKK"
     gene            complement(76191..77495)
                     /locus_tag="ACGXWR_000067"
     CDS             complement(76191..77495)
                     /locus_tag="ACGXWR_000067"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFK0801691.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(77492..78001)
                     /locus_tag="ACGXWR_000068"
     CDS             complement(77492..78001)
                     /locus_tag="ACGXWR_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801692.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(78176..80311)
                     /locus_tag="ACGXWR_000069"
     CDS             complement(78176..80311)
                     /locus_tag="ACGXWR_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HFK0801693.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(80394..82049)
                     /locus_tag="ACGXWR_000070"
     CDS             complement(80394..82049)
                     /locus_tag="ACGXWR_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFK0801694.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(82051..82365)
                     /locus_tag="ACGXWR_000071"
     CDS             complement(82051..82365)
                     /locus_tag="ACGXWR_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFK0801695.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            82535..82795
                     /locus_tag="ACGXWR_000072"
     CDS             82535..82795
                     /locus_tag="ACGXWR_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HFK0801696.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            82809..83123
                     /locus_tag="ACGXWR_000073"
     CDS             82809..83123
                     /locus_tag="ACGXWR_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HFK0801697.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(83853..84407)
                     /locus_tag="ACGXWR_000074"
     CDS             complement(83853..84407)
                     /locus_tag="ACGXWR_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HFK0801698.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(84533..86462)
                     /locus_tag="ACGXWR_000075"
                     /pseudo
     CDS             complement(84533..86462)
                     /locus_tag="ACGXWR_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(86768..87484)
                     /locus_tag="ACGXWR_000076"
     CDS             complement(86768..87484)
                     /locus_tag="ACGXWR_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFK0801699.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(87485..89308)
                     /gene="glpO"
                     /locus_tag="ACGXWR_000077"
     CDS             complement(87485..89308)
                     /gene="glpO"
                     /locus_tag="ACGXWR_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HFK0801700.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(89322..90818)
                     /gene="glpK"
                     /locus_tag="ACGXWR_000078"
     CDS             complement(89322..90818)
                     /gene="glpK"
                     /locus_tag="ACGXWR_000078"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HFK0801701.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(90954..92414)
                     /locus_tag="ACGXWR_000079"
     CDS             complement(90954..92414)
                     /locus_tag="ACGXWR_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0801702.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(92404..93699)
                     /locus_tag="ACGXWR_000080"
     CDS             complement(92404..93699)
                     /locus_tag="ACGXWR_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFK0801703.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(94031..94708)
                     /locus_tag="ACGXWR_000081"
     CDS             complement(94031..94708)
                     /locus_tag="ACGXWR_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HFK0801704.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(94738..95829)
                     /locus_tag="ACGXWR_000082"
     CDS             complement(94738..95829)
                     /locus_tag="ACGXWR_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HFK0801705.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(95930..96364)
                     /locus_tag="ACGXWR_000083"
     CDS             complement(95930..96364)
                     /locus_tag="ACGXWR_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFK0801706.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(96948..98405)
                     /locus_tag="ACGXWR_000084"
     CDS             complement(96948..98405)
                     /locus_tag="ACGXWR_000084"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFK0801707.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(98402..100297)
                     /locus_tag="ACGXWR_000085"
     CDS             complement(98402..100297)
                     /locus_tag="ACGXWR_000085"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFK0801708.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(100355..102130)
                     /locus_tag="ACGXWR_000086"
     CDS             complement(100355..102130)
                     /locus_tag="ACGXWR_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFK0801709.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(102180..103676)
                     /locus_tag="ACGXWR_000087"
     CDS             complement(102180..103676)
                     /locus_tag="ACGXWR_000087"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFK0801710.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(103870..105492)
                     /locus_tag="ACGXWR_000088"
     CDS             complement(103870..105492)
                     /locus_tag="ACGXWR_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFK0801711.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(105820..107133)
                     /locus_tag="ACGXWR_000089"
     CDS             complement(105820..107133)
                     /locus_tag="ACGXWR_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFK0801712.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(107378..107602)
                     /locus_tag="ACGXWR_000090"
     CDS             complement(107378..107602)
                     /locus_tag="ACGXWR_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801713.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(107622..108044)
                     /locus_tag="ACGXWR_000091"
     CDS             complement(107622..108044)
                     /locus_tag="ACGXWR_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFK0801714.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(108186..108896)
                     /locus_tag="ACGXWR_000092"
     CDS             complement(108186..108896)
                     /locus_tag="ACGXWR_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HFK0801715.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(108914..109411)
                     /locus_tag="ACGXWR_000093"
     CDS             complement(108914..109411)
                     /locus_tag="ACGXWR_000093"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFK0801716.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(109448..109900)
                     /locus_tag="ACGXWR_000094"
     CDS             complement(109448..109900)
                     /locus_tag="ACGXWR_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFK0801717.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(110035..110640)
                     /locus_tag="ACGXWR_000095"
     CDS             complement(110035..110640)
                     /locus_tag="ACGXWR_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFK0801718.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(111090..111710)
                     /locus_tag="ACGXWR_000096"
     CDS             complement(111090..111710)
                     /locus_tag="ACGXWR_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFK0801719.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(111712..112581)
                     /locus_tag="ACGXWR_000097"
     CDS             complement(111712..112581)
                     /locus_tag="ACGXWR_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFK0801720.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(112604..113011)
                     /locus_tag="ACGXWR_000098"
     CDS             complement(112604..113011)
                     /locus_tag="ACGXWR_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFK0801721.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(113030..114319)
                     /locus_tag="ACGXWR_000099"
     CDS             complement(113030..114319)
                     /locus_tag="ACGXWR_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFK0801722.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(114346..114648)
                     /locus_tag="ACGXWR_000100"
     CDS             complement(114346..114648)
                     /locus_tag="ACGXWR_000100"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFK0801723.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(114673..116766)
                     /locus_tag="ACGXWR_000101"
     CDS             complement(114673..116766)
                     /locus_tag="ACGXWR_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFK0801724.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(117255..118019)
                     /locus_tag="ACGXWR_000102"
     CDS             complement(117255..118019)
                     /locus_tag="ACGXWR_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HFK0801725.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(118130..118999)
                     /gene="mdcB"
                     /locus_tag="ACGXWR_000103"
     CDS             complement(118130..118999)
                     /gene="mdcB"
                     /locus_tag="ACGXWR_000103"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046917 - triphosphoribosyl-dephospho-CoA
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0019361 -
                     2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HFK0801726.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(119024..120100)
                     /locus_tag="ACGXWR_000104"
     CDS             complement(119024..120100)
                     /locus_tag="ACGXWR_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFK0801727.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(120124..120717)
                     /locus_tag="ACGXWR_000105"
     CDS             complement(120124..120717)
                     /locus_tag="ACGXWR_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HFK0801728.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(120721..122397)
                     /gene="mdcD"
                     /locus_tag="ACGXWR_000106"
     CDS             complement(120721..122397)
                     /gene="mdcD"
                     /locus_tag="ACGXWR_000106"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HFK0801729.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(122387..122686)
                     /locus_tag="ACGXWR_000107"
     CDS             complement(122387..122686)
                     /locus_tag="ACGXWR_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HFK0801730.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(122788..124434)
                     /gene="mdcA"
                     /locus_tag="ACGXWR_000108"
     CDS             complement(122788..124434)
                     /gene="mdcA"
                     /locus_tag="ACGXWR_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015451 - decarboxylation-driven active
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HFK0801731.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(124441..125352)
                     /locus_tag="ACGXWR_000109"
     CDS             complement(124441..125352)
                     /locus_tag="ACGXWR_000109"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFK0801732.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            125472..126329
                     /locus_tag="ACGXWR_000110"
     CDS             125472..126329
                     /locus_tag="ACGXWR_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFK0801733.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(126516..126878)
                     /locus_tag="ACGXWR_000111"
     CDS             complement(126516..126878)
                     /locus_tag="ACGXWR_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HFK0801734.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(127067..127249)
                     /locus_tag="ACGXWR_000112"
     CDS             complement(127067..127249)
                     /locus_tag="ACGXWR_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801735.1"
                     /translation="MIFFISEYINQTPFYSKNTEKINGGQVSTDFSIIVYFSGAFTDD
                     KNFIMNLKNDTTKIKK"
     gene            127224..128663
                     /locus_tag="ACGXWR_000113"
     CDS             127224..128663
                     /locus_tag="ACGXWR_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0801736.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(128670..131222)
                     /locus_tag="ACGXWR_000114"
     CDS             complement(128670..131222)
                     /locus_tag="ACGXWR_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HFK0801737.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(131336..132667)
                     /locus_tag="ACGXWR_000115"
     CDS             complement(131336..132667)
                     /locus_tag="ACGXWR_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFK0801738.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(132633..134111)
                     /locus_tag="ACGXWR_000116"
     CDS             complement(132633..134111)
                     /locus_tag="ACGXWR_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFK0801739.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(134416..136251)
                     /gene="tdc"
                     /locus_tag="ACGXWR_000117"
     CDS             complement(134416..136251)
                     /gene="tdc"
                     /locus_tag="ACGXWR_000117"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFK0801740.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            136721..138148
                     /locus_tag="ACGXWR_000118"
     CDS             136721..138148
                     /locus_tag="ACGXWR_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0801741.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(138240..138605)
                     /locus_tag="ACGXWR_000119"
     CDS             complement(138240..138605)
                     /locus_tag="ACGXWR_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFK0801742.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(138602..138967)
                     /locus_tag="ACGXWR_000120"
     CDS             complement(138602..138967)
                     /locus_tag="ACGXWR_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFK0801743.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(139159..139407)
                     /locus_tag="ACGXWR_000121"
     CDS             complement(139159..139407)
                     /locus_tag="ACGXWR_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801744.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            139406..139534
                     /locus_tag="ACGXWR_000122"
     CDS             139406..139534
                     /locus_tag="ACGXWR_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HFK0801745.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            139591..141285
                     /locus_tag="ACGXWR_000123"
     CDS             139591..141285
                     /locus_tag="ACGXWR_000123"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050151 - oleate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HFK0801746.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            141352..141681
                     /locus_tag="ACGXWR_000124"
     CDS             141352..141681
                     /locus_tag="ACGXWR_000124"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801747.1"
                     /translation="MFLIWLDLLPQMQAFEHRLPRGCEKAALHQVIRTPKLKLLLMFL
                     TWLDLLPQMQAFEHHLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQAFEHRLP
                     RGYEKGV"
     gene            142059..143192
                     /locus_tag="ACGXWR_000125"
     CDS             142059..143192
                     /locus_tag="ACGXWR_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HFK0801748.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            143223..143543
                     /locus_tag="ACGXWR_000126"
     CDS             143223..143543
                     /locus_tag="ACGXWR_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HFK0801749.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(143572..144036)
                     /locus_tag="ACGXWR_000127"
     CDS             complement(143572..144036)
                     /locus_tag="ACGXWR_000127"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFK0801750.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(144167..145420)
                     /locus_tag="ACGXWR_000128"
     CDS             complement(144167..145420)
                     /locus_tag="ACGXWR_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFK0801751.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLASGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(145449..145766)
                     /locus_tag="ACGXWR_000129"
     CDS             complement(145449..145766)
                     /locus_tag="ACGXWR_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFK0801752.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(145792..146112)
                     /locus_tag="ACGXWR_000130"
     CDS             complement(145792..146112)
                     /locus_tag="ACGXWR_000130"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFK0801753.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(146576..147991)
                     /locus_tag="ACGXWR_000131"
     CDS             complement(146576..147991)
                     /locus_tag="ACGXWR_000131"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFK0801754.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(148008..149324)
                     /locus_tag="ACGXWR_000132"
     CDS             complement(148008..149324)
                     /locus_tag="ACGXWR_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFK0801755.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(149474..150172)
                     /locus_tag="ACGXWR_000133"
     CDS             complement(149474..150172)
                     /locus_tag="ACGXWR_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HFK0801756.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(150461..151454)
                     /locus_tag="ACGXWR_000134"
                     /pseudo
     CDS             complement(150461..151454)
                     /locus_tag="ACGXWR_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
     gene            complement(151535..152368)
                     /gene="msrA"
                     /locus_tag="ACGXWR_000135"
     CDS             complement(151535..152368)
                     /gene="msrA"
                     /locus_tag="ACGXWR_000135"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFK0801757.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDTRENISVKEQ
                     LSKLEVTLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQDERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(152602..153345)
                     /gene="truA"
                     /locus_tag="ACGXWR_000136"
     CDS             complement(152602..153345)
                     /gene="truA"
                     /locus_tag="ACGXWR_000136"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFK0801758.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYRS"
     gene            complement(153536..154171)
                     /locus_tag="ACGXWR_000137"
     CDS             complement(153536..154171)
                     /locus_tag="ACGXWR_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HFK0801759.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(154318..155538)
                     /gene="sstT"
                     /locus_tag="ACGXWR_000138"
     CDS             complement(154318..155538)
                     /gene="sstT"
                     /locus_tag="ACGXWR_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HFK0801760.1"
                     /translation="MSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSCLKAIAPI
                     LVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPITLQETVSE
                     KAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEPTKELVDQI
                     SIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLFVALVVYP
                     FLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKESYSISIP
                     LGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGVAGGSLLL
                     IPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELGARKRSGE
                     KIKLKDCLDGLSER"
     gene            complement(155880..156557)
                     /locus_tag="ACGXWR_000139"
     CDS             complement(155880..156557)
                     /locus_tag="ACGXWR_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HFK0801761.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATIATTTTTSTESKPTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSESSEQVEQTLWNADKSAQLEAFMA
                     TWGQTMGQQYKSYTNQMSVDLYGLKVPQVILNGEWKMAIGGVPVSAEWSESGTGQADY
                     QITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELKNG
                     FNQIVYG"
     gene            complement(156808..157350)
                     /locus_tag="ACGXWR_000140"
     CDS             complement(156808..157350)
                     /locus_tag="ACGXWR_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HFK0801762.1"
                     /translation="MNIVEEKFAQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLKQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(157355..157582)
                     /locus_tag="ACGXWR_000141"
     CDS             complement(157355..157582)
                     /locus_tag="ACGXWR_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HFK0801763.1"
                     /translation="MKKMIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSTKVKEA"
     gene            complement(157661..159541)
                     /locus_tag="ACGXWR_000142"
     CDS             complement(157661..159541)
                     /locus_tag="ACGXWR_000142"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFK0801764.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIIIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDNVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDQFSQYYTPTVLLIALLVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQRGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAMLKQAGAKHLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLH
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSSFGSLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLIGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            159842..160162
                     /locus_tag="ACGXWR_000143"
     CDS             159842..160162
                     /locus_tag="ACGXWR_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFK0801765.1"
                     /translation="MDKYLYLLAGNKIQKSLMDFIQELECTFHKKFTHSILLKLLIHT
                     ACLIERTLINGHELKIISEDDTRPSHETIFHVKKAFKNIETEFGITVSYDECFFIYDI
                     IASK"
BASE COUNT        47301 a        33237 c        27802 g        51936 t
ORIGIN      
        1 aaaatcaaaa taactgatta tttacgtttg aataatgaga atttttctat atattctcta
       61 ttttgataat agtattctca ttttcaaaat aaataaggga ggtgtgacaa aattcttgtc
      121 acacctccct tttccgaata aactgtgttc cagaaatagc ttcttcgaaa ataagctgaa
      181 atttcacaaa aatttgagaa gcaattttcg tacattcctt cttctttctt gaaactgacc
      241 acttctgtca caccctctct tctatcactt tccttttttc acacgactcc cggtttcttt
      301 gataaatctc gatactttca attttcttga atttttcatt tgaggtacac atagatacag
      361 acgatttctt gctctagtca tcgcaacata aaatagtctt cgttcttctt ctatcgtcgt
      421 tactggttct gcttttattt cattaaagtc gattactttc ttttctgtcg ctccgttata
      481 aggcaaactt ccttcgttac aaccaatcaa aaagacattt cggtaactaa gacctttact
      541 tttgtgaatg ctctggatac atagtgcatc aagttttcct tgtctgtaag caatcaagcg
      601 ggtttttaat tctttagctg tcgcttgggt ttcttgcgat aaggcttgga gtcttctgaa
      661 agtagcatgc tgctttactt cttctcgtat ccattcttga tcactctggt cgatttcctt
      721 agctatacgt ggcagatgaa gatagctttg aacaagcgaa tagatttctt gatgctggtc
      781 tgttttacgc aacgcttcct caaactctcg gatttctgca gatttcgatt ttaaattggg
      841 gcttatcgac aaaatataat ctgcaacggc tatattttga tatttaggag aaaagtattg
      901 atcgcattca ctttttttca ggtagcagtc tgccatcagc tgccggagca attgctggta
      961 ggcctgattt ttcttttgca gattcagtgc tgtttgccaa tgaacaattt tttgatagaa
     1021 atgttggaaa gacttgatac caaagatacc ttcatatgga ctatctgctt ccagtacaaa
     1081 aggaatattc gttttcagca gagattggac aagctgctgc gtttgtgaag ctgatcggta
     1141 taatatgatt gattccttat atttcccatt tttttgaata aatgtctgaa tttgtttgat
     1201 tagccactga ctttctgctt tagtatcaga aaacaaatag gcttccataa cacctgcttc
     1261 tttttgtgct ggaatcatcg cctttggtat ccgatcattt ttattatagc tgatcaatct
     1321 atttgctcct tggacaatag ctgcccgaga acgataatta gttaataaga aaagagtttt
     1381 ggtaggatat tctttttcaa agttcttgat gtatgctggc tctgatcctc tgaatccata
     1441 gatactctga tcatcatctc caacaacaat caacttgatc ctgttttcct ttgtcatccg
     1501 tttcacgatt tcccattgaa gtggattagt atcttgaaat tcatcaatga atagataatc
     1561 atatttttgg ccgatataat gctggatctc ctcattctcc aaagcgcttt tcagattttg
     1621 gagtacatca ttgaactcta gcaattgctg gcttcttttt tgttcttgga gttccgtgag
     1681 caatccatac agtcgttctg atatcggctg tcgtgcattc ttatcaatgg aatcatattt
     1741 ttctttaact aactgaacca tttcttctac tgaaaggttc atattctgcc aatagtctaa
     1801 ccgagaagca atcgtttttt ctccatattg atcaaatata taaagattat atttacgtat
     1861 cagctgttgc aaaacagcat tcactttttg tgcagtatcc tttgaaaagt ctccttgtat
     1921 tccttgcatt gctacttcag gaaattttcg acaaatttca ttgtatatcc taaaaaagat
     1981 actatggaat gttccgatat ggacagcggt ttttctctgg ctgaaattat ctactcgttt
     2041 ttttagttca tttgcagcgt tccttgtaaa agtgatcatt agtatgcgtt cttcgtctac
     2101 ttgtttttgc gtcatcagat aaacagcttt tgcacagatt gtttgcgttt tgccgctccc
     2161 agctcctgct atgattcgaa gatgtttctt catatcatat gtgatagctg ctttttgttc
     2221 ttgattgaag cgattatagg aacgtttctc catcatttta aagaaagagc tgtttccttc
     2281 actttctttt acttgtactt cttcctcaat aagtccgggt gcttcgccat aagccgcttc
     2341 ataggtagca atgatttctt cttgtagccg aaagacttgt tgaagctttt tatacttgtt
     2401 ctcccagcgt ttcaattctt tttgtaatcg gagaatttct ttttcattca actgattgat
     2461 ttccttccca tctttcttct ttgaatttgt ttatttcaag ttggttattt aaagtttcgt
     2521 tgtctatttt ttctttatac taacagacct ttctaaaaat gaaaatggga agcgatatga
     2581 ttttagtttt ctgaaaattt ttcctttttt tcaatcgttt atgctaagat aaggaagaca
     2641 aaaatattca taaaaggtga tgaaaaaaat gcagacttcc tttcacgagg ggcgtacaat
     2701 aggacttttg ctgacattta tcggaggagc catggacagt tatacttata tccaatatgg
     2761 tgcttttgcc tctgctcaaa ctggcaatat cattctatcg atcatccaag catttgacgg
     2821 agaatggcta agtgttggta aaaaagtatt gtctaccctt ttctttttct tagggattct
     2881 tctaacaaag tatctaattg attattttag aaaaaaagaa aaacatttct ggcgcttgtt
     2941 tgttctatat tatgaagcag tgattttttt ctttgttagt ttgacacccg tccatgagca
     3001 tcccgcatta gtaacgattt tgattgcttt tactgcatcg atccagtggg tagcttttga
     3061 taaaatcaac gggcgtgcct acactaattt atttacaact ggaaatttaa aaggggtagc
     3121 aacgaactta tatgattatt gtatttctaa agaaaaagca gattttgatc gatttttcca
     3181 ctatctaagt gtcgttcttg cctttatcgc aggagctatt gtccttgttt tctgtcatca
     3241 tctgtttggc gcccattcga ttttgatcgt ttccatttta tttttgatca tggccctcac
     3301 tcagacattt catttatggc aattttatca tacgaatcgg ttcactattt gatctcaatg
     3361 aatcaaaaaa actaagcaag atgctgctca cagagaaata tctgcgagtg agcaatttgc
     3421 ttagttttta tattatttag ttgtaaagat tccctttgct ttcgggttat ttgtagtgta
     3481 gcggatcgac tgggcatctg cctcttctgt cattttcttt gcccgcatct tgatttcttg
     3541 tacgatttgt tctccacatg ccggatcggc tacgaaatca tatttgtccc catcgatcac
     3601 tattttggga catatatcaa actgttcata ccactcttcg tatcgtcgat tgagttcttt
     3661 atagtaggaa tagagttcag gatcttgttc tagctgttca tattcccggc ctcttttttt
     3721 gattctcgct aacatagttt caaaggatac acgaatataa accagtagat ctggtttctt
     3781 ttgtggcgaa atttcttcta actccttcag catcgtttct aaaagacctt catactgctt
     3841 tacttctact tcagaaacac gccctaaatc tgcattcaaa tgaaacagca tactatcttc
     3901 gtagatggag cggtctagta cgttgtcatc atggctgaaa gcatctttga ttgccaaaaa
     3961 gcgtttgttc aaaaagaaaa tctgtaataa aaaagtatac ttttctggat tagaataaaa
     4021 tagcggcaat acttcattat cttccacgtt ctcataaaaa ggttttgttt ctaaatcttg
     4081 ggcaagcatt tcagttagtg tgcttttccc tgcaccgatc gttcctgcaa caatgatcac
     4141 aattatcggc atccttcctg taataaaatc tgttcttcat tttactactt catttataga
     4201 aataaaagcc ttgactttat ctgctcctta aaagctactt ctctaaaagt agccaaaagt
     4261 aactcctatt catgaaaata aaggctgtga caaaagtctt gtcgcagccc ttttttcaaa
     4321 taaacagtat tctcctgcca acacctcggt cacaaggcaa tattcataaa acatgaaaag
     4381 ctgtttttta acattattcc ttgtaactca gagctaaacg ggagactcac aacctcttta
     4441 tgctctcaac attttatctg tttttattct tctattgtac ttgatttgcg tacaactaac
     4501 tgccagtgca gattatgagc ggtatcattg tcttctactg cgcatttcat gacacgtatc
     4561 atcacactat tttcatagat tttttctatt tttcctttta ttggtgattc aaataaatca
     4621 gatttaaatg catatgtttc gccgacttca aacaattgtt cattttccat aagaatccct
     4681 ccatcacctt ttataaggtc agtaattttt taacataaat cactcgaaaa agcacaaact
     4741 tgtcataaaa agtacttttc gtatcaaaac tgtcactttt tttggtaagg ttcttggaaa
     4801 acgaagattt ttttaggaga tcatgacggt tttgatgtca aaaccacttt ttatgaaaca
     4861 aaagacgttt tttatttttt ttagcataaa atttgtggtg gaggtacgta tgagatgaaa
     4921 gataaagttg tgaacaaatt attagaagcc ttattcagcg gagacaaatc ggaagaagat
     4981 atggtgtatg tccaagtaaa atttgtctta gaagttttat tgaataatct tggaaaacta
     5041 gcggtcgttc tagtcttttc tctggtgaca ggctcatggg cggaaacagg aatcaccttt
     5101 ctttcttata tctgcatccg cagatatgct tatggattgc attccgactc tgaattcgtt
     5161 tgtctgctgt ggacactact ttatttatgg ggcgttccct tggtgatgaa acatctgcaa
     5221 ttgactatct ccttcccaat gatggtcttt ttgttaatca gctgcttttt gttactgctt
     5281 cgctatggat caagaggtac agcaatcaat cccattgaac ccgagaaacg tcccccatta
     5341 ttaaagaagg cgatcagcat gtttctaatt ttttctctca ttacgttatt tttctcagct
     5401 tcttactttt ctacctattt gctacttggg attgttttag aaatagctac gttgcttcct
     5461 attacaaact acttgatgaa ttttggagga atctttcatg aaaaaaacaa tcattaaaca
     5521 attaactaac ttatctgact tttttgtatc tggctgctgc tttggtatga gttctgaatt
     5581 caaaatccct gaaaaattaa aaaaataata cgccaattgt gctataattt ggtaaaaatc
     5641 aatgggagct gtactttatg tttttatggt ccatagcgtt gcaatatttg atttacacaa
     5701 tttgtatctt attgattgac catcacatcc gatacaaata tctgtttgcg ggagtcattc
     5761 tgatttcttg tattttgatt ggatgggtct attcgatttt agggattttt actgctctaa
     5821 ttgctatagg aatgctgatg cttacttttt tcttcttttc gacttcgcgt caacaattgg
     5881 tttacgcgct tccttttggg ttattgacgt cgcttttagg agatcactta acaagcatcg
     5941 gcgatttttt tgttttgaaa tcttcggtta ttgaaccagg agattcattg cagtattttc
     6001 acattgtctt atccgctttt ttatctgctt tattagcttt ttgtttaaaa aaatcgttag
     6061 agacttggtt tcacactgtg gaccgccgta tgatcggtac gatcgggaca ttgatattat
     6121 ttacatacta tatcattatt ttttataccc gtttttctgg tgaaacacct gatgtcttag
     6181 ctttgaatac gagttttttc attctatatc tgtgtgttgg cctgatcatc ttggtttatt
     6241 attggaaaat ctctaataag aaattagctg atcagttatt agagcaacaa gtcaggatgc
     6301 aacaggatta tatcaaagat ctagaaaaaa actatcaaga cttgagagaa ttcaaacatg
     6361 attaccaaaa tctgcttttt tctcttcaca gctatatttc agaaggcgac ttagaaggat
     6421 tacggtctta ttatgatcaa acgatattac ctacacgcca gatgatgaac ctttttccgg
     6481 ccaatctaag tatgttggat aatatgaaag ttcctgagat ccgtagttta ctgtcattaa
     6541 aactcatgat ggcacaggaa aaagggttga tcgtccagct tcattttcct gagccaatcg
     6601 aactggatac gaaacatacg gtaaaccttg tacgtatgct tggtattatc ttggacaatg
     6661 cgattgaagg agctagtgct gcaaagaaga aaaaaatcga attgaccata ctcaagaaga
     6721 atcattccgt gatgattcgt gtgatcaata caacaacaaa tacattaccg ttaaaccagt
     6781 tgaaacaaaa agggttctca acaaaaacaa atccaaaaaa cgaaggcctt ggcttgttta
     6841 tcttggatga attgacaaag accaatcctt atcttttcct tgaaacatca attgaaaacc
     6901 agcgtttttc tcaaacgatt tatatacaaa taaaataaag gagtaatgat atgattccca
     6961 tttatatttg tgaagacgat ccaaaacaat tagaagtttt atcaacggtg atcaaaaata
     7021 gaatcatgat tgaaaactta gacagttatg tccatatttc tacctctgat ccggaagaac
     7081 ttctcaatgc agccaagatc agaacttctt cttttggtat ttacttttta gatatcgaac
     7141 tagaagacag tgaaatggat ggtgtagcga tcggtaaatt gatccgtgaa ttagatcctt
     7201 taggaaaaat aatctatgtg acttcccata cggaaatgtc gatgaaaatc ttaaaaagca
     7261 acatcgaacc gactgattat atcgtcaaag aagatcttta tgatttaaaa gaaaatgtcg
     7321 agcatatcct gagcaaaatt ttcgaagatt ttcaaatgtc ccaaatccaa aaagatatct
     7381 tcaaaataga gtttaatgat gagatcaaat ttttaccgat caaagacatc caatattttt
     7441 ctacttcgct aggagcgcca cataaactgg aagtccattt gactcatgcc caattacaat
     7501 tctatgagaa gatcaaagaa atcgagaaaa tgcatcggaa ttttatccgt tgtcataaat
     7561 cctatgttat caatacacaa aatgtgcggt cgattaataa aaaaaccaga gaagtcacgt
     7621 tggcaaacgg cgagaccatc ccagcctcta tccgtggatt aaagaaattg atttcataaa
     7681 aagaaccgaa tagtttggac cgactaaatg accagccgat ccaaaccctt cggttctttt
     7741 ttgcctatca gtgcaaaagc atttcctgtg caatttcacg tccatccatt gtatctggat
     7801 aaaatgttgg ccaattctcc atttctttca gcaatacttc ttgactttca tttcctgcat
     7861 ataaatgaaa atgttcggag tcagccggtg caatcgtgtg atcactgaat tgaatatatc
     7921 taaaagcgcc actttcctta tcttctgctt cgaatagata ccttacgcca cggtttcctg
     7981 cctcgtaggt caagatttct ttccctacat aacgataatt tgaacgtttc gttgttccat
     8041 tcttaaacgt aaatgccatc tctttctcac tgatcttgat tgaagcaata tctgtttgat
     8101 agcccttcgt ataatattct ttatattctt gtgctgtctt atcctgattc aatttttctt
     8161 tatattcaaa aacaggatca aaagtcccat cttctacata cgtatctact gtttgccaag
     8221 ttcctgccca atctgaaaga gagcgatctt gtacatcctc gtcttcaaaa taaccgttgt
     8281 agacgctctt ttcttttttg ggggtcaaag tatcttctag cgggttttct gtctctgtcg
     8341 tttttttcaa cgcttcgagg tttgcttcca tgatagaaag atagttttct ccattttcta
     8401 tttgttcatt cgtcaatcct tccaaaggat tcaatacttc taaagataca cctgcttcgt
     8461 ttgctaacgt tctggcaata ctatctttgg cgttttcttc aaaataaata tagttgattc
     8521 catgttcttt aacaaagtgt ttcagttcag caattctcgc cgcagacggt tcttcactag
     8581 aagaaagacc agcaatcgat acttgattca atccatattc taacgctaga tagttgaatg
     8641 cagcatgttg cgtgacaaaa gatctttgtt ttgcttgctt aaaggtttct tgataaagct
     8701 gatggagtgc ttgaagtttc tcggtatagg ctgctgcatt ttttgtccat acttcctgtt
     8761 tttctgggta agcttcaatc agctgatcac gtatgtttgc tacctgcttg attgctaaac
     8821 ttggagctag ccatacatgt gggtctagct catgtgtatg gccttcttcc ccgtgttcat
     8881 ggtcatgatc atgtccttct tcacttcccg gaagtaaaag cataccttct gtcgctttta
     8941 tcgtatggac attgccttct tgtaatattt tttggattgc ggggacccat gtttccatgt
     9001 tttcatcatt ataaacaaag atatctgtat cttggatctt tgccatgtct ttagcagaag
     9061 gttcataatc gtgggaatca gtccctgctg gaatcaataa ctctacttct ccttcatccc
     9121 cgacgattgc ttttgtaaaa tcatacatgg gataaaaggt cgtcatcacg ctcaattttt
     9181 ctttactgtc ctcggctttc ccacttgccc cgcaagcagt taacatacct gctaaaacca
     9241 gcatggccaa tatacctatc aatcgtttca tttatgacac tcctcttctc atcttctttc
     9301 atttgaatgt tccgattcgc ttttcgcaaa ccgtaatagt tacgttttag caacaggatt
     9361 taatttatca tatggttaaa agaactgtca agcgttttct tattttaatt gatgagaaag
     9421 tttatatgaa tgattgacga tatttttgca atcaacctct atcattttcc ttttataccc
     9481 gcttttgtct ataatgaagt tatagataaa ggaggaaaaa gagtgaaaaa agaaacagat
     9541 acaacgaatc gtttgatccg ctttttagga ggaaaaacct cttactatgt tttaggaata
     9601 gttatcttac ttgcgctgat catttatttt ttccatcaga tctcgtttat attcaagcct
     9661 gtcggaatca ttatcgctac tatcttgccc ccattattgt ttgcactgat cttgtattat
     9721 cttttggaac cagtcatcaa acgtttgagc aagcaccttt cgaggaactt gtcagtcatt
     9781 atcgtttatg tgattatttt atttttattg gggcttggaa gcatatggct tattcctttt
     9841 cttgaagaac aggcaaagac attgatcagt agtttgccag atttgtttca agattttcaa
     9901 gagagtctcc gacaattttt ggagaaaaca ccttttgccg attcatttaa tcaatttttc
     9961 gcttctattg acgacgtgac gtctgatata gctggattta ttggaaatta ttgggaaagt
    10021 ggcgcacaac ggatcagcaa cattttttca actgttacag ctatttttat tactttattt
    10081 actggtccaa ttgtcgcttt tttccttttg agagatcctc aaaaatttta tcagtcagtt
    10141 ttagcgattg tcccaccagc atttcgtaca gattttaaaa atttgacaaa gattgctaat
    10201 caacaattgg gttcatttct aaaggggcaa atcattgctt catttatcct tggagcagtc
    10261 tactgggttt gtttcttact gatcggatta gaatttgcta gtgttttagc tatttctgct
    10321 gggttgttat gtatcattcc atatattggg ccgtttatcg ccttctttcc aggtttgatc
    10381 attgcattcc aagactctac ttttatggct gtcaaatttg tcattgtctg gtttgccgta
    10441 caacttctcc acggtgactt ggtgattcct cgagtaatgg gtgatcgttt acagatccat
    10501 ccgattacga tcttaatcgt tttacttgtc atgggtgatc taatgggaat tgtgggcgtt
    10561 atttttggta ttcctatcta tacgttagtc aaattactcg ttacttttat tttccgtaaa
    10621 ttcaaacaac gctacaataa attttatggc gataaaggag agtatgaaaa ctcttcattt
    10681 tctgaagaag attattttaa ataaaacaca aaacgtcgat cttacgagaa tagctcgtag
    10741 gaacgacgtt ttgtgttttt gttttaattt ttcagcaaag caattgcctg gtatggtttt
    10801 agctccagac tttgatgaag aacagtatcg gaataattat cgataagaat attggcttct
    10861 gtgaatcctt ctgggatggc gatccttgta tctttatcat agaaatttgt taatacaagc
    10921 agctgctgtc cttcaaattg gcgaagaaag ccataaactt ccggatgatt tgcttcataa
    10981 gcatgataat ctccttgtgc aacgattgga tatgtttttc tcagccgaat caatttcttg
    11041 taataggaca aaatagaatc ttcagaagat agttcttttt ctacattaat ctcttctagc
    11101 ttgcctccaa cttttaacca aggtttccct gtagtaaatc ctgcttgttc tgtgtctgac
    11161 cattgcatgg gtgttcgaga gttatcgcga gattttgctt tgatccgacg aaacgcttct
    11221 ttttctgtga atccttgttc aaggagtaac ttataagcat tcaaactttc tacgtcaata
    11281 tagtcggaaa tcgatgaata gtctgggtcg atcatgccga tttcttctcc catataaata
    11341 tagggcgtcc cacggttcaa atggatcatg gttgctagca tctctgctcc ttgttttcga
    11401 tactgatcga tagctacaaa tcgattgagc gcacgtggct gatcatgatt attaaaaaat
    11461 agagcattcc agccgttacc ctcactcatc ttttctcccc atgtatgaaa tagtcgcttt
    11521 aattctgcaa aatcaaatgg aggagtagac catttattcc cattttcata atcgactttc
    11581 aaatgatgga aattaaagac cattgataat tcttctctac taggttctgt atacaagata
    11641 caattttcga tcgtcgtaga gctcatttca ccgactgtga tgatagtgga atccgtccca
    11701 aacgttgctt ggttcaattc ttttagatac gtatgggtga ttggtttgtc cgtatattca
    11761 ggtttgccat cattttcttt attatttttc aattgttcgt ctttaccgat aacattgata
    11821 acatcgaaac ggaatccttt tacccctttt tccatccaaa aacgaacaac tttgaatagt
    11881 tcctctctta ctgcttggtt ccgccagttc aagtcagctt gtgtccgatc atataagtgc
    11941 aaataatatt tccccgtatc tccaaatggc gaccaagcac ttccaccaaa ttttgatacc
    12001 caatccgttg gctcttctct taaaatgaag aagtcctgat aatgctggtc ccctgctagt
    12061 gcttttttga accattcatg ttctgtcgaa acgtgattca gcaccatatc gagcatgatt
    12121 tctatccggt atttctttgc ttcggctatt agctgttcga attcctccat cgtaccaaag
    12181 ataggatcga tggctgtgta atcagagata tcataaccgt tgtctttttg agggcttgga
    12241 taaatagggt ttagccaaat catgtcgatg cctagatcat tcagatacgg gagtttttct
    12301 ttgattcctt ttaaatctcc aattccatca ccattactgt ctttgtaaga tttgggatag
    12361 atttggtaaa tgactttgtc tttaaatgtc atggatattt acctccattc aactgattta
    12421 ttacctacca caacttatat atacaagtta tcatttatta ttataactga accgaaagcg
    12481 tttgtaaaat ttatctttat acattctaag aggtctgttg cccaataaaa aacaagagat
    12541 cagacatgta tttgtctatc ctcttgttta aaatagcaaa atattcttgt ttcttctata
    12601 aatggtgttc aaaagctttt atctacggca atcagtcttc tcaaatgtaa aacatgagga
    12661 gctaatttta tttgagtatt ctttttgctc gatgcaggac ggctttttta caacctctga
    12721 ttcatggtgt tcaatcagct gtccttcggt attagctcaa aaaacggcaa aatatgaaaa
    12781 actattttgc cgtttgtttc tctaatactc aggtcaaacc gctgatttca caacctctgt
    12841 ttttattcat tcgatttcaa cgcatcaatc atatcgatat gctttaattt gaaatgggta
    12901 acaatcatca caataaccgt aaatacgata gttaatcctg ctgataagac ataagcccac
    12961 catgtgatca ctaatggaaa gatgacattc tccatagacg cttgttgcaa gatgaagtca
    13021 gtcaatatat atcctacacc aaatcctccg atgattccta aaagagtaaa gatgatattt
    13081 tctcgaacaa tgtacatcgt gacttcttta tcaaaaaatc caaggacttt tattgtagat
    13141 aattcgcgta cacgctcgga aatattgata ttagttagat tatacaagac gataaaagcc
    13201 agcagtcctg ataatacgac aaagattaag acaaccgagt ctaagttcgc cattgattct
    13261 tcttgcgttt cgatttgttt ggacatgaaa gacgtatttg tcacagcgtc tgtggcaagc
    13321 agtttctcgg aaagcatttc ttcttctttt gttgtcatct tatctgtacg cagcaaaaat
    13381 gcattatcca tcatcgattg atcagtaact gaagcataat attcagggga catataaata
    13441 aagctaccta gatagttttt cacgatttct tttacttcga ctttccattc tttttgatct
    13501 tcatcataaa gcgaaatatg atctcctgta gataagtcaa atagttctgc tactttttgc
    13561 gtaatagcga ttcctgtttt aggcaaggag cgtgggttct cttcaagatc agttaaatgg
    13621 ataaaacgat ccaaatcagc tgttttactt ggtacgatca ctgtcagact ttgcgaagca
    13681 tgtccttttt ttctcaattc tacggtttga gtatgaatag ctaggatctc atttactttt
    13741 tcttgcttct gcagcatatc cgctgctttt tgacgactat cttccgtgga tgaatccaat
    13801 gtaacgattg cttgatagtc aatgatcggt ccaaattgtt tggctgaaac agaacttaga
    13861 gaatctttca atcccacgcc tgcaaccatc agcccggcac atccagcaat tccgataatc
    13921 gccataagca ttcttgactt atatcggaag agatttcggt aactgatttt ttgattaaag
    13981 ctaaggcgtg accacagcgg agtgatgtat tcaagaaaaa tgcgtttccc tggcttcggt
    14041 gctttcggtt gaagcaatgc agcaggccgt tctcttaaat ctttgaataa aacgatcatt
    14101 gcagcgccaa atgcggcaat gaagaatgcg gcagctgctt gtaaaatcgg cggccagtca
    14161 taaaaaataa gcgcactccc aatatcatac cgctcgttag acagctcaaa aatgatcctt
    14221 ggcaaaagat tcgttcctaa tatcgttcct aaaacaatac ctatccctga ggctagactt
    14281 gcatagattg catatttttt tgcgatttca actttcgtat aacctaacgc ctttaatgtc
    14341 ccgatttccc tgcggttttc ttctaccata cgtgtcattg tcgtaaaggt gatcaatgcg
    14401 gcaataaaga aaaagaaaac aggaaaaaca ttggcaatcg cagcgatacg atcagacaga
    14461 tcaccaaatt cttgaaaacc gacattttct gaacgttcat tgtataggta tgatggttta
    14521 gttaaatttt caattttttc tgcatttcga ttcaattctt cctctgcaga ggccagttca
    14581 cgttctttct caactaattg cctttcttgt tcagcaagtt gagcttcttg ttgagataat
    14641 gtttgaacag cgattgttcg ttgcgcttca ggaagctgct ggatagttgc tgactgttgc
    14701 gctaactgtt ttttagcatc ttctaaccgt gttcttgctt gcgttgtttg tgctttgcca
    14761 tccgctattt tttgctgtgc cggttctaat tcttcgttgg ccgatttttt cagctcttct
    14821 aagcgttctt cgggtcgatc ttgtaaatac ttttctgcct tttcttgatt ttgctccatt
    14881 ttatctttgt aagctttgct gtacgtattc aaattcttta cgtttgtaaa atcaagatat
    14941 aagacagaat aaatatctgt tttaaaaacg gattcaggta aatagacaaa ataatcgacg
    15001 ctaccatttc cgacgttcgc gtatcctctc tccaaattgt tgatgaacaa tggagaacgg
    15061 acaaagcccg tgatggtata ctctttttct ttcaattcat ctgaatcaat ctgataaata
    15121 tcaccgattt tatacccttc atcttccgct ttttcatcca atacaagctg gtttggtttt
    15181 tccgggagtt ttccatcagt taattgtagc ttgttctgct tgttattttt gttataagaa
    15241 aatatttgaa tcacttcgtt tttgccagta ttggaataat agatctgttt tcctgtttct
    15301 acttttgcat ctgggatctt ttctgcttga gcaatatctt tttgtgtcaa gccaccagta
    15361 gaaacgattt gcaaatcaga aagtcctgct gtaccaacat agtgatccat cgttttttgc
    15421 atgacaggtc cagcagtttt gacacctaca aataaaagtg ttcctagcat gacaataagg
    15481 atgattgcaa tgaatcgtcc tttagattgc cgaatttcgc gaaaacctgc tttaagatat
    15541 gttcttgttt tcataaaatc cccctaccat acaatctcat caatggatga aggatgatca
    15601 tttaattcaa cagaccttac tttagcatca ttaatgtgaa tgactctatc agcgatgggc
    15661 gctaaagcag aattatgtgt aatgatcaaa acggtattgc cgtgttgtct gctagcgttt
    15721 tgcaataatt tcaatacttg cttgcccgtt tcaaaatcca gcgcgcctgt cggttcatca
    15781 cataaaagaa gtttgggatt tttagctagt gcacgagcaa ttgaaaccct ctgctgttcg
    15841 cctcctgata attgggacgg aaagttattc aatcgatgag ctaggcccac ttgcctcaat
    15901 acctctacag gatcaagcgc atcaggagaa acttccgttg ccaattccac attttctttt
    15961 gctgttagat taggaacgag attgtagaat tggaaaacga accctacatc tgttcgtcgg
    16021 taagcagtaa gctgtttatc tgaaaattgc gcaatatctg tgtcatcaat aatgatctga
    16081 ccttcatcag gtgtatccat cccacctaaa atattaagaa tcgttgactt tcctgctcca
    16141 cttggaccaa gtataatcac taattcgcct ttttcaattg aaaaagaaat atcgtcattt
    16201 gctgtaatgg tcgtttctcc cattttgtat cgtttgtatt cattttttac ttcgacatac
    16261 ttcactctga ttcctccatt ttcacgatat ttctcgctat atctatgcat cgaatgcgtt
    16321 ttctcacact tatttatttt accactgaat ttctctagac taaagaaagg aatcctttaa
    16381 tttagttgac aaataaacga tttatgattt acttacataa aaaacattgt tatttgaaag
    16441 aaggaacatc atgaatgatt taaaggaaaa tatgattttt gatttatcaa aaactgcttt
    16501 tgtcgcgatc gacatgcaaa aagagatcgt aaataacggt acactctctc cacacactgc
    16561 agcatctatt ctgacaaaca atgatttgtt agtaagaaca ttgaaacgta ccgctgcctt
    16621 gaaagtttta gtgaacgtag acatctccac tttcccttat ttgagtcaac aaactgatat
    16681 gggtggaatg actgcttctg tacctccaga attcactgat ttacttttga aggattcttt
    16741 gaaagataca gataatatgt tgactatcac aaaatacaat ccaagtgctt tttttggtac
    16801 ttctcttgat cttcaacttc gccggcgtgg aatcgaaact atcattttaa gcggtgtagc
    16861 gacaacaaac ggtgtatatg ctactgcatt agatgccttt caacacgggt accatatcgt
    16921 gcttgctgaa gatgcttgca gtgatcgtga caaagaatcc catcaattgt tcataaaaaa
    16981 gatatttccg aaaactgcac gagtacgctc aacgaaacaa ataatcgaag ctatccaaca
    17041 aagcaaataa gtactggcac acgtgatttt catttacttc tttttgattt catgggaaaa
    17101 taaccacagg atttagatag gagtatgaac atggtgaaaa aaaagatcac aatcaaagaa
    17161 gtcgctaaac tttccggcgt ttcaatcaca actgtctcct tgatattaaa tggaaatacg
    17221 gagaaattca gtccgaaaac tgttcagaaa gttttagctg ccaaagaaga attaggctat
    17281 cagcctgact attttgctag acaaatgatt accaaggaaa cgaaaacaat tggtgtactc
    17341 gttcctgata tcacgaatcc attcttcagt acactgatgc gaggaattga ggatatcttg
    17401 tataagcaga atttcgtcac gatattatgt aatgctgatt ctgatcatca aaaagaaatc
    17461 gaatatctag ccgagctcac acgtcgaggt gtggatggat tcattatcgc gacttctgct
    17521 gtctctacag atgcaatcaa cgaaaatttg aaaaaacaag gccggccctt cattgttttg
    17581 gatcagaaaa aatctgaagg atttagtgat gccgtacgaa cagacgattt tcgcggtggt
    17641 tacctagcgg gcatgcactt gcttagtcta ggacatcaaa cgatcgccct tgtctatcct
    17701 gaaaatccac cggaaaatgt ccacgctcgg attgaggggt ttaaatctgc tcttgatgtt
    17761 taccaaatcc ctcacgacca actgatcctc ttacctacac agttctcaaa acaaggtggc
    17821 taccagatca cagcagaact tcttgattct gctgcaactg gtgtgtttgc tttaaatgat
    17881 gaattagctt ttggattata tcgcggatta gaggaagctg gaaaaagcat ccctgaagac
    17941 tacagcatta ttggctatga taatatagat atgtgcgagt atatcaagcc gaaactgaca
    18001 acgatcgcac aaccaatctt cgaattggga caaacatctg ccaagttatt gttagatcgg
    18061 atccaattcc cagaaaaaga atgggaagaa aaaagattac ctgtacgatt agaaaaaaga
    18121 ttttcaactg cacccttgaa atagctttca aggtgtgcta tatttttatc gaactattaa
    18181 aacgttttac taaaacgttt taaaaaataa ttttcccatc aaaataaatg agatagttgg
    18241 aggtttgtaa aatgaacacg gttacagtaa ttggaagtat taatatggac actacccttc
    18301 gtttaaccaa catgcccaag ccaggcgaaa cgatgcatgc gcatgagatt tttcacgctg
    18361 gcggaggtaa aggtgccaac caagcagtgg cagccaaacg ttcaggcgca cggacatctt
    18421 ttattggagg cgttggggct gacagcgaag gacaacagtt attagatcta ctgacaaaag
    18481 aaaacatcga tacatctggg atagctgaaa tccaaggcgc cacaaccgga caagcaatga
    18541 ttatggtaga cgcagcagga gaaaatagta tcttgatcca tgcaggggca aataatgctt
    18601 tccatgaaca agaagtccta aaaaacaagc aactgattac aaacagtgac tttattattg
    18661 ctcagtttga aagtagctta gatgcgacga tcctagcttt ttctattgca aaagacgcag
    18721 gaaaaacaac gatcctgaat cctgcaccag ctcgtgaaac gattcctact gaactacttg
    18781 aaaagacaga tatcattata ccaaatgaaa cagaaacaga aatcattaca ggaatcagag
    18841 tgacagatca taacagtttg gtcgcagcag ccgaaaaact ccatgaatta ggtattggaa
    18901 cagtaatcat tacactaggc agtgccggcg ctttctatca tacagaaaaa gaacacggta
    18961 tcgtccctgc ttttaaagtg gatgccgttg acacaacagc cgcaggtgat acatttattg
    19021 gcgcattaag cagcacactt cagccagacc ttagtaactt gaaagaagcg atcctttatg
    19081 gaaatctagc ctcttctgtt gctgtgcagt cttatggtgc gcaaccttct atcccttacc
    19141 gcgaagcttt agaacaatca gcagtctaaa attaacaatg agaggaagaa acaaacatga
    19201 aaaaaggaaa agtaatcaat tcagatattt cacgagtaat cgcacaaatg gggcactttg
    19261 ataaattaag tatcggggat gcaggcatgc ctgtcccctt tggtactgaa aaaatagatt
    19321 tggctgtctc aaacggtctt ccaagttttt tatctgtttt agaaaacgtt ttagaagaac
    19381 ttgaggtaca atcgattgaa ttggcggaag aaataaagac aatgaacccg gaaatattgg
    19441 aaaaaatcaa attattgtta ccagatacac cgattagctt tatcccacat gaagaaatga
    19501 aaaaagagtt gaataactgt catgcattta ttcgtacagg cgaaatgaca ccttacgcca
    19561 atattatatt agtgagtgga gtggtcttct aatggaaacg acaatgaatc ctgaacagat
    19621 ggtactgtcc gagcagattc atatgctgat tgaacagttg ggaggaaaag acaatattga
    19681 ttctgtcctt ccatgtgcga ctcggcttcg tatcaaattg aaaaaacagc cagtagccaa
    19741 tgcagaaaaa ttaaaacagc aaatcccttc cattaagtat ttcattttac tcgatagata
    19801 tgcagaaata atcatggatc agggattggc tcctgcttac aaggaattga cgcgtcaaat
    19861 cgatcattca gctccgaaag aaaagctaaa tccgatcgaa aaactatttg gtttgatatc
    19921 ggaaatcttt acgccgatca ttccgctgtt tgccggttct ggtatattaa aaggtctggt
    19981 tgttttagcg actacgattg gctggcttag tgaaacaagc ggaacttatc atattttgtc
    20041 tgctgcgtcg aatgccgtct tttattttct gccaatcttt cttgcttttt ctgctgccaa
    20101 aacgtttaaa gtgaatggat atattgcggc tgtcattgct gcagcactga ttgaaccgaa
    20161 tctgacctct ttactttcag acagtggcaa agcagctact gattttctgg ggattcctgt
    20221 agtactgatg cagtatacgt ctactgtcat gccggcgatt ttaggtattt tcttttattc
    20281 ttttgttgaa aaattcctca aaaaatatat tcgcgaaaat atgcaattag tatttgtacc
    20341 tttactttca ttagttatca cggttccttt gacgttaatg gtattcgggc ctgcgggtgt
    20401 ttaccttggc gaaggtttag ctgccgcaat tacttggatg atggatatta acggaccgat
    20461 cagtggcgca atcatcgctg gtggttggaa tattttggta atatttggta tccaatgggc
    20521 tgtaaaccct gtcatgatca gtaatatctc tgcttatggg ttcgaccgaa tcgttccgtt
    20581 gacaggagca gccaattttg gaatggctgg tgcagcttta ggtgtatttc tgcgaagtaa
    20641 acgttcaaaa acccgttcga tctccggttc tgcttttgct tcgattttac ttgcgggagt
    20701 gaccgaacca actgtttacg gaattgcgat cccattgaaa aaaccatttg ttgctgcttg
    20761 cattggtgca gctgctggtg gagctgtaat gggatttgcc caagtgaaag cgatcgcttt
    20821 tgtatttggt agtctgacca cattgcctgc attcatttcc ggtacttttt tctggtactt
    20881 agcaggactg gctgttagtc tagtcgtagc aatgatcact actctcgtta gcgggtttga
    20941 tgaagaccta atgtcttatg aatagttaat gaaaaagact gaagtatgag atgtttatca
    21001 catatttcag tctttttctt tttaggatca ttatttttat aaatttttgt gatactttcc
    21061 aaactttggt ataatttaca tatgcataac catttttatc cccacttgtt tatccccaaa
    21121 caaaggtggt ctatgcaata aaatgaacgt caaagaaaaa cgaatgaatg ctcgttgctt
    21181 atttacaaat tgttttattt agaatacaca gacagattta tgaaaagaaa aagcttttcg
    21241 acacgattat ctgttccaaa aaatgtctaa tgaatgctga ataagacaga aaatcaatga
    21301 aaggaaaagg actagtttat tatgaaaaat aaaaaaacga tacgtttgct agctgctact
    21361 tggctgattg ctccgtctgt tttgtcgacc aataccgtat ttgccgtaga taatcaaata
    21421 gctgatcaaa cagtcacaac agatacgact acatccagct cagctactag tgaaacaacg
    21481 gattctttta cagaagaccc aactggaaca actaactcaa caacaggatc gaccgagcca
    21541 actgaaattg atccggctga tccatcagaa aatgaaaagc cagccgagac atattccctt
    21601 acaattgctc cttctttgat tggtaagatc caactgactg cttcgacagc ggattcccct
    21661 gaacagcaac ctttggatat tacggaaagt ggaacggtag aaggtttatt agcggaaacg
    21721 aaggtaactt acactattac gccagctgaa ggtgaacaaa ttgcttcagt cgctgttaat
    21781 ggtgccaaag aagtaaatta tgatgcaaag acctttacag taggtacgaa caatttatct
    21841 attactgcag aatttaaagc tggaccggat acttcaacag agaaaccaac tgatcctagt
    21901 gaagaagtcc ctagtacacc agatccggaa acgccaaaca aaccagatgt gggtaataac
    21961 aacaataata atggttcaaa taattcaaac aataataaca ataattcgaa cagcgggaat
    22021 tcttcgaatc aaacaaaccc atctggatcg aataacaatg gaaatactca gagagaacca
    22081 aaccatccaa acaatggttc atcgaatggc ggaacgaaca atgcttcatc tcgtccaaat
    22141 acagcaaatc aaagcggtat agagaatcca tcttctgctt cttctgattt tgttgtaaaa
    22201 tcaccaattg atgctgtatt gcctacaaat acaacgaatg tccaacaagc aatcgttcga
    22261 gaagcattca agcatcttgg aaaaccatat gtatggggag caaaaggtcc aaatactttt
    22321 gactgttctg gtttgactta ttacgtatat atgaaagcaa ccggtcatta tatcggtggc
    22381 tggacaggcg aacagcaata tgcaggtacg cagattccag taagtcaggc ccaacctggc
    22441 gacctcgtct tctggggacc ttcttccggt gttactcacc atgtaggtat ctatattggg
    22501 aacggacaat ttatccatgc gcctcaacca ggagataaag ttcgagtaac ttctatttca
    22561 gatttcacgc ctgattttgc tgtccgagta aacttagcag gtttacctgc tgcttcaggt
    22621 tcgctgacag gcggctcatc tattttagat ggattagatg gctcgttcca tttcagtcaa
    22681 aaccaaacaa ctgatcagtt cttgaaaaag attgcagatg atgcacagga aatcgggcaa
    22741 aaagaaggaa tctacgcatc agtcatgatg gctcaagcta tccttgaaag tggatctgga
    22801 aacagcttat tatcaagcga accaaatcat aacctttttg gtatcaaagg atcatataaa
    22861 ggaagcagcg tgaccttcaa tacacttgaa caagatagtt ccggacaaag ctaccaaatc
    22921 cgcgcacaat tccgtaaata tccttcttac aaggaaagtt tggaagacta tgccgacttg
    22981 atcaaaaatg gactgactgg caatcctgat ttctacaaac caacttggaa gtcggaaaca
    23041 aaagactaca aagaagcaac caaatatttg gaaggacgtt atgctacaga tcgccaatat
    23101 tcacaaaaat tgaacgcgat catcgaagcg tacgacctga caaaatatga tgaaccgaaa
    23161 aaagaagcag caacaactga agaagcaaac gctgaaatcc tcaatatgtc taagcgattc
    23221 gatgtgccaa tcaaatggac aacagatggc gtgccaatca caggattaga attttcaacg
    23281 ataaaacgcg tcaacaacgc ttcttccatc ttccgtgtcg cttcaatctg ggatttgtgg
    23341 aacaatttta cggcaagaca gataccagaa acaactactc gtacagttaa agctgcaact
    23401 gttcctgtac taaccttgtt aagtttagac aaatcattct ggcttgatct gcctttaaag
    23461 aaatagaata aattaaaaag gggatgtgac actgtcacac tcccttttta atttattcta
    23521 tttctttata tttattttgt attccgttac aaactcgcgt acttggttag gttccagagt
    23581 gacatctcca aaactttcaa gtcgctccgc tcctggcagt tcttgagtct caaatgtgat
    23641 accgccatga tttactaatt tattcccgcg catttccggt ccatcttctc caaaatttgc
    23701 tgtaaaaatc acgattcctg aagcatctgt ttttacttgg atcgatactt tttcatctgg
    23761 gcttgtcaat tccgcagcat ttagtaaacc agattgtttt ttcaacaaaa atggatgatc
    23821 gatgccgccc actatcattg attggcgaaa atcactggca aagacctcac ctaatttttt
    23881 aggacgttgg aagtcaaatg ctgtgccact tactgaaact acttctcctg taggcgttgt
    23941 atctttattg agcgtagcaa ataatcggct attcaaccaa agtatatgtt cgtcgattga
    24001 ctgtgctgga tcaccggtta aattgaaata gacatgattt gtaggattga atactgtttt
    24061 gcggtcactg atcccttgga ccgtcactcg ccatgtatca tcgttcgtca gcgtataccg
    24121 tacttctaca tctaaagttc caggaaatcc gttttccata tctgggctag tctgatagaa
    24181 aatgaccgat gcttcgtttt caccattgat gactgtataa tgccactgct tggcttcaaa
    24241 gctaggtgca ccaccatgta aacaatgacc agtgtccggg tctgttttta cttcgaacgt
    24301 ttcatcatct aatttgaatg tgccattcgt aatccgtcca gccatacgtc cgattgaagc
    24361 accgatataa gggtcttttt ctagatattc ttttgcttca tcaaaaccta agatcaactc
    24421 tcgtttttca ttatcgatta ttgtttgaaa atgaacaacc cgtgccccaa gatcactgac
    24481 agacaaagat gtcccatttt gattcgtgat cgtaatcaag tgatagtttt cgccaaaatt
    24541 ttgttcattg atttccatgt tccttgcacc ctcttttctt tcatttgcac tgattccagt
    24601 atacatggaa accgttttct taacagctta ttccgtgagt aacgagaaaa aatttactat
    24661 attctaataa aagaccgtga aaaaaaggtt gtgacaaaaa tattgtcaca acctcttttt
    24721 ccgaacaaac ggtgttcaaa agcttgcatc tgcggtaata agcccaacca aacgaaaaat
    24781 atgaggagct atttttgctt ggctgttctt attacttgat gcaggacagc tttttcacaa
    24841 tctctttttc aatacgattc cagtatataa ccatgtcgtc agtacatagt agatgaaata
    24901 caatacgaag aatatcgtaa acggaaccca aatatctttg tatggatttt gcatgaatag
    24961 accaaacatt tgtaatccga ataagacatg gactacacct aagattcctg gtgctaagaa
    25021 taacacgcct acttctctac ggatcgattg tttaagcaac ccgcgtcgtg ttcctatctt
    25081 ttcaagcatt tcataacgag caatgtcact cttgcttcct gacaagatct tgaacatcaa
    25141 acagctagca agcatggtca agaaagctaa acctaggaag aatcccataa attcaaaacc
    25201 agagaataga ccattataca cttcatacat ttcatatttc tggttgctgt actctacttt
    25261 ttgcaaagat ggattgttca ttttattttg agcaacaagt gtttcgattg gtttcaggtt
    25321 tgcttggaag tcttttacct gaactagctg taaagtggat tgtggcaagt tcagttgatc
    25381 aaattctgat tgactgacta ccttgatttc tttttcttgc tgttccggca attcatagct
    25441 tcgaagttcc tcttgtacag tcagttcatt cattttttta gcaggaactt tttctttcgt
    25501 gatcttcggc ggtgttccat cttcatgttt tatcatgatc aatggttgag ccgcaaattc
    25561 acttgcatta tagtaaatcg ttcccgcatc ttctttttga gtataagaag cagaaagtgt
    25621 tggtgaaagt tctttgattt tttgctgatc ttctgcccga ggattattca tcactagatc
    25681 atatccagaa ttgttttctg tcaagtctgc aatttcattt ttaaaaccta atcctaccgt
    25741 caaagcgccc agtgccaagg caaacagcat agcgaccatt gagagcattt gtgtatattc
    25801 acgaatacga aagtttaact gtgacaatgt gaaattgttc aattttttca atgaaatctg
    25861 ttctgatttc tttagtaatg ataaaaagaa aatgatcaca gaatggaaaa tgaaataagt
    25921 tcctaatacg atcgtaacta aggctacccc tataccaaag acttgatagg tccccacgtg
    25981 tttcatcata tagtaaccgc agcctagaaa agcaattccc agtactactt caaggaaaaa
    26041 caagaattta tgctgcttga ttcttgttgg tgtctgatcc gcacgaatca atgctaaaat
    26101 cggttttttg acaatcgaaa aagcattgac aacagcagct aataaaaaca aaacagcaaa
    26161 aaacaaaaca gtgatcaaca acccgtgaat actaaaaggt gtaaaatgcg aaatattgag
    26221 atctaactga tccactaata atcggtggac gatacttgtc aatcctacac cgacagctga
    26281 acccactaaa gtagctgcga tccctactaa gaatgtttca gaaaaaatca tctgtgcgat
    26341 ttttctgcct tttgctccca gcatcataaa cattgcatag tctttttgcc gcatcgtcat
    26401 caaaaaggaa tttgcatata aaatataaac gaatgtgatg atccctagta aaacagaacc
    26461 gaatcggaaa atgataactg tagccgcaac gatcgtatta cttttcaaaa aagcttcgtt
    26521 gcttgccatt gattcaaaca tgtaaaaaat agcagatgcc ataactaatc ctgagaataa
    26581 caccaagtag tctcttaaac ggctcttgat cccagtaagt gataatttcc aaagcatagt
    26641 caatctcccc ctactgttcc aagtttccaa gaatagatag tatttctcga tagaaggaat
    26701 cacggctttg atctccacgt ttcacttctt gatggatacc gccatccttg atgaataaaa
    26761 tacgttggca ataacttgca gaaaacggat catgcgtcac aagaagaatc gatacatgat
    26821 cttttgtatt caattcgtcc atcgtatcta aaagatcccg ggcacttttg gaatccagcg
    26881 cacctgtagg ctcatcccct aatagaatcg ttggttgtgt gatcaatgca cgtgcggcgg
    26941 cgacccgttg tttttgtcca ccggaaatct cagaaggata gctttccaaa atatgagaga
    27001 tggataaacg ttctgcaatt ttttggacac gttgcttgat ttcttttggt ctgacgcctt
    27061 gtaaagaaag aggaacagcg atattttctt gtgctgtcaa gctttctaat aaattgaaat
    27121 cttggaaaat aaagccaatc tcattcgcac gaaaatctgc tagttgattt ccttttaatg
    27181 tggtcacatc tttttgattg attcggatat gcccatctgt tggtttatct aatgtggata
    27241 aaatattcaa aagtgtcgac ttaccagaac cagaagcgcc catgatccca ataaattcgc
    27301 ctttttctac atcgaagctg atgccgctta atgcttgcgt ctttttctca ttgttttttc
    27361 cgtatacttt tgttacattc tgtacttcga ctattttgtt catttctttc cctacccttt
    27421 aattagtttt tccagtgctg ttttcggcac gtcttttttt tcgacttctt catacgaagt
    27481 gacaccttta tttttgttcc aggtgatttt taaatatgct cctttacgaa gcggtcgagt
    27541 caattgtccc ttgaagtcca gttctttttc cttaccctct ttcgtatagc caggcaggat
    27601 atatctatag ttgactgttt cttgtccaga gtctgatttt gaaactgttt ttgtaccatc
    27661 tgtcgtaatt tgtacatagt attcttctcc acccataact acgtaatctg cgattttcac
    27721 ccctgcaagt accacaacga tgaaaacaag tagaccgatc agaagttttt tcactttttc
    27781 cccttctctc ttactttata tactgattat agaaaaaagc gaacaattct gccttcgaat
    27841 caactatcat tcttctttca attttgtcat tttctttaaa acaactaaaa aaagagttca
    27901 agacaataat ccgtcctaaa ctccttcttc ctatcttaca aaaagtatgt cacttacggt
    27961 ctttcatgtc gcctgtattg ataacaggtt gcgttccttt gtctgtaatg attgagacaa
    28021 gtaaattatt gatcaattgg actttccgat catcggtgaa attgatttct tgtccatctt
    28081 cgatttgctc taaggccatt tgagtgattg tgacagctcc ttcaacaatg gtttgtcgag
    28141 cagacaaaat ggcttttgct tgttgacgtt ggagcatggc actagcgatt tctgttgcat
    28201 aggctaaatg gttcaagcgt gtttcgatta cttcgacacc tgctactgct aaacgctctt
    28261 gcagctcttt ttgcaactcg tcagacactg ccgtcgtgtt tcctcgaagc gtcaaatcat
    28321 tctcattgaa tgtatcatac gggtattggc tagcgatatg ccgaatggct gtctcacttt
    28381 ggatttctac aaaatcttga taatacgcta catcgaataa tgcctttgct gtatcaacga
    28441 ctttaaagac tactactgct gagatttcga tggggtttcc atccaaatca ttgactttta
    28501 aaacagaact attgaaattc cgaactttca acgaaacagt cattttttgt gccaaaggta
    28561 tcgtaaggaa aaagccattt tctcgaatcg tacctaaata ttgtccaaaa aacaaaatta
    28621 cttttgcttg attaggactg actacagttg ccgaacttaa caacaataac gtgatcaacc
    28681 aaagaaaaat acttaaaaaa agtgcccaaa ctttcgcttg ccacatacct aaatagaaga
    28741 aaaacaatcc aactaaagct aatacgacca atccgacaat ccctgcataa ccattgatat
    28801 aaaatgctct tttttctctc atgctacttc ctgcgctcct ttatccttca ataaatatct
    28861 aatgttactt ttttaatttt tttttcgaat acgcgccatt acaccttcta gttctaactc
    28921 tttgtcttca gtgatgtacc aaccgcttgc ctgtgtccct ccggctgcct gcggtaaata
    28981 atccaatttt gttcgaaccc agtgcttttc ttctgtaaaa tagtcttcta ccaagacctc
    29041 tagatccatc cctgctgaaa gaggcaaatc ttcccgaaca gatttaaaga taaatcgttc
    29101 cttcttccca tcatacttca atattcctgt atcgataatc ggtaaagaat aataatccag
    29161 ctctttcttc accgtcaata aatgtttgaa aacttcatgg tacacttgct ctaattggcg
    29221 accttctgaa ttgttcgggt aattaaccat cactttttct ttgtctggat catagaaggt
    29281 ttggcttagt tgagtgatat aagtatgtaa tctttccatt tctgttttta acttttctct
    29341 ttgaccttct tctaccttca tatactcttt caccctgttt tctttttaga tattttcttt
    29401 cttattttac tatagttatg tgcgttaagc gatgaaaaac agcaaagatt ggaaggatct
    29461 ttgctgtttt ttcttaaaat atccagttga gtacaggatc aatctgtttc attgtcctct
    29521 tgatccgtcg taatattgat cgatgtgtct ttagcagtga tctttagctt tttctgtcct
    29581 tgttctaaca aagtatttgt tattggctgg tagtcttttt caatataaga ttcaccagac
    29641 gtttggatag tatagccact gttttccatc tcatgcaaag ataaattgcc accgtttagg
    29701 atgacttttc cttctttgct gatcaaactg tcttctagat ggaagttgct gttttcacct
    29761 gtgacgatca agttatccac attggcctca tctaatcgaa gtgagcctaa ttcatctttc
    29821 gcagttattg ttcctcctgt aaattcattg aacgataccc agccatcatg tgtcttagta
    29881 ttcacttttt tgattgatac ttcgttgata tcaattgcac tattattccc ttcgattgtc
    29941 aattcagata attcatgatc tgcagggaca acaatagtga tttgtgcact tgtgtcttct
    30001 aaactaatga ttgcacctgt tgattttttg actgcattca cagtcaacac gccatttttc
    30061 tcctttattt ctggcttttc tgtcttatca taagtcgttt ttatctcaaa atccaatccg
    30121 cgtatgaccg aaactgtttg attttctgca tggatgacga ttttgtttgc atccttgatt
    30181 ttttttgtct cagtaaccat atcgatcaac cgaggaccat tatcccaagt cagactcttt
    30241 tgagcgccta atgtataagt tgcacctgct aggaggccac cagtaagcat cagaccaata
    30301 ccggtaatca aaaaatgttt caatctcaat ttatgtgtcc tccttcaaac gcccgctgaa
    30361 tgcagatctc tttttgtaat aaaacgtcgt cccatccatt taacaaagtt catcatgaca
    30421 taaaaaagcc cttttgttcc tttcagcaac agtggcgaaa taaatactgc gcttcctgtg
    30481 gcgaacagac cgacaccgat aaagaataat ccactcagaa tcgattgtcc aaacacactg
    30541 attcctgaga tgatcatgaa taggccaaca cctaagatac tgatacataa aacatagata
    30601 ctaaaaatga gcgctagtaa agcaaccaat agtcccccaa taaccaatat aaaccccagt
    30661 gctagtggaa tgaggacagg agaagcaaat aaaccgataa tgattaacca aatcaggcga
    30721 atttgtcttt ttggattttt cactaactcg ttttctgctt gttcttcttc tgaaaagtaa
    30781 ctgattttta attttaaggc aaactgcttt ggtgtaccat attcatcaat gatctgatct
    30841 aatgtttttc cagaatctaa aaaatattcc tcataatact ggatcaaatc aaaacgatcg
    30901 tcttcaggaa tttcttgaag atgatccaca acttcattca aatattcatt catttgtgct
    30961 ctcctccaat aaccggtcta aagaatctcg aaaaacaatc cattcatcaa taatttcttc
    31021 taaatgacga cttcccattg gtgtcaacga gtaatatcga cggtttctgc cttcaaaagg
    31081 ttcatcatag gtctcaagat atccttcttt tttcaatctt ctcaaaaccg gatatagtgt
    31141 agattcactg acagagagac tttcttgtac gatttttgtt aaggcatacc catacatatc
    31201 ttccttgctt aatgctgcta gcacagtacc atcaagaaga acagttggaa tctggatgtg
    31261 cattacgtca ccttctattc tcaagtgtaa tattttattt caatctatat tatacaacat
    31321 ataatatagt ttcaaaatca gtttgtcaaa tacaaaaaaa ctgactaaaa gatttgatcc
    31381 tttttagtca gcaaaaaatg gcttctcttt gatttttatt ataacagtgg cataatccaa
    31441 tttgtccaca tccagctcag tggcatgata acgatcattg caggtatcat gtcagctact
    31501 gggaacattt tcacgttgat cattctaaaa ccggtagcga ccatcaagaa tccgccgcaa
    31561 gctttaaaat ctaagatcat gtctggtgta gtcaatggat aaataaattt tgccaataag
    31621 aacaaaatat aaaaaataat gaattgggga attgctatca cagaaacgac ataccctaaa
    31681 ttacacgcaa aaatagctgc tgtgaaaaaa tcaaggacag atttagaaat caaaatcgta
    31741 ctgtctcctg tcatcccaga atctaaactt ccatagatcc ccgtaccact tgcacaaaat
    31801 agaacaatga ccgtcactaa tgtgctgata aattcatcgt gggtcatacc aagcttttca
    31861 ctagggaaga ttttagaaat aggtacttgc atcagcgcag cccccttatt tatcccatta
    31921 cctaaatgaa caatcaaacc aatcgctgtt cctatcacta aagcaaaaat aacagccggc
    31981 atatttttca tcggcgcaat ggaatagatt cccatcccca tcgaacacac accaaaaacc
    32041 atcgtcagct gtgctttaaa atgttcactt aatttatttc ctactaatcc gccaattagt
    32101 ccgccaaaca aaacggaacc tacattgatc aaaactccag ttggcatcaa aaaactcctc
    32161 tctttttcta cgaagcgaaa aaaatcagaa aaatttctgt aattattgct ttcgctgcaa
    32221 gaaagattgt aacagacaga gaagattaca ccaattcatt ttttgtgtta aagtattctt
    32281 tattggaata agtaggagga atatgatgga tatccataaa ttcgaagttt ttcttgattt
    32341 agccgaaaca atgaatttca ccaaaactgc tgatcgacaa ttcaccaccc aaggaaatat
    32401 ttctaaacag attctttcgt tagaaacaga attagacgtc aaattattcg aacgcgccca
    32461 tagaaaaatc gaattgaccg aagctggaag cttattgctc ccatatgtaa aaaatgtcgt
    32521 agaacaatac catgctatgc aagaagtgct tgaaacctat acgaaagaca acaatctttc
    32581 attaaatatc ttaacgatac cgacaatgat caattataaa ggtttttcca aaatcaccga
    32641 gtttttgaaa cgccatcctg aatttacagt ccagttgaaa gaagtggaaa gtgtcgaatt
    32701 aacttacaat gacgccaatg aacatagtga cacgatccac tttgctagaa gtttccaggc
    32761 cccaccaagt tcgattgagt ggttgcctac tgaaacagac gattttgtag cagttctacc
    32821 taaaaatcat cctttagcta gtaaaaagaa attggatcta agcgaactga aaaaggagaa
    32881 ctttttgctc cttggcccca ctacgaactt gtatcaacct gtactagatc tgtgtcgcga
    32941 agctggattt gaaccaaaaa tctcttataa aggagcaaga atcgacttga tcatcaatat
    33001 gattgcaaat gacatgggga ttgctattgt tatggaaaaa acagtcaaga atctattaaa
    33061 agaaaatact gtgattctcc ctatttctcc aacaacagag agttatcttg catttactcg
    33121 taaagtcggt gagcattctt tggcttcaga tacattttgg gagtatttaa atcaagaaga
    33181 aaactaagcc ctacattttc tgtccatcta tccacccaaa aaaagagagc gacgcatgac
    33241 tttcgctctc tttcttgcat catgtccttg tttcaatgac acctctaaca tttctcgtag
    33301 ttcaataaga aagcagcgat ttttatgcca aaagaaccgt aagaacattt ccctaatcac
    33361 aaaaaaacga ctaaaaaccc ctaaaaacct tcaatagaat ttttaggggt tttattcttt
    33421 ttcctattgt ttacttaacc gtatcattgc tgtcgttcct actccttcga tactgctata
    33481 atcaatacgt ccatcatgca gttctagaat ttttttaacc agtgaaagtc ctagcccatt
    33541 cccagaaatt tgacgacttg tatctccttg ataaaatttt tcaaacattc gatctctggt
    33601 ctcttcattc attcctacac ctgaatcggt cacttccagt acaatctctg tggctgtctc
    33661 aaatagtttg atatgaatct gtccattgat ttgattgtac tttatggcgt tatccatgat
    33721 attcagccac acttggtaca aaaactcttc attgcctgtg taatttactg cagcaagttc
    33781 gatatccaat tctagctgtt ctttctccca tttaggctga aaaaaaacga ttacttctct
    33841 gatttgttca tctaatcgat actctttctt ttccagttgg atacgctggt tttccagttt
    33901 gttcaatttt aagatgttct ctgttaattg tgaaagctgc gtgatacttt cgataatccg
    33961 atataaaaat atttggcgtt cttcgtcaga gagatttggg gcttgtaaca attgaacata
    34021 tccttggatt gttgctagtg gtgttttgaa ttcatgggat acactggaca caaagtcatt
    34081 cctcagtgtc tcgatactat tgagttcttg gaccataacg ttgaaatctt tatacagttg
    34141 ctgtacttct gctactttct gctgttcatc cattcgaatc gaaaaatctc ccgttgctac
    34201 cagactcata tttgtcccta gcgcactgat tggatgcagg atacgccgcc caacaaaaat
    34261 cgatattcct gtacccacga ccatactgaa ccccgcaaag acgaataacg ggtataacgt
    34321 tggttttcca gccgattcag caggcgagat agaatgtcga gacaataaga aaataaaacc
    34381 gagaaaacac agcagtgtca ctaagatcga aatgaagaca atactagcaa aatagatcca
    34441 taattgtgaa aatagctttt ttttcatctt taaataaccg ccttatagcc tagtccccgt
    34501 actgtgatga tttgaaaatc ttccgtcttt tcaaaacggg tccttaaacg tttgatatgt
    34561 acatcgatcg ttcgttcttc tgtattcgta tctaatcccc aaatatcatc catcaactgt
    34621 tggcgagtga agatcttgtt gggataagac agtaatttat acagaagcag aaattctttt
    34681 tgaggcagaa tcaacgaatg ctgatcttgt aacactgtat aagcatctag ctctaatttt
    34741 gtttgtccga ttatcaagct actgctgtaa ttgatctttg aacgtcgaag caatgcttcc
    34801 acacgtagga tcatctcatt gacatcgatg ggttttgtca tataatcatc tgctcctaat
    34861 ttgaacccgc gtttcttatc ctcaaaatcg gcctttgccg taatcattag aacaggtgtg
    34921 tcaaatctgg tgctacgtaa tgagtctagc aagtcatagc catccatttt cggcatcatg
    34981 atatctgtaa tgattaattc tatacgtgtc gcttctagtt ttttcagcgc atcctctcca
    35041 ttcaatgcgg tgatgactga aaagcccgct cgttccaaca cagaacggta aagcaactgt
    35101 aattgcggat catcttctac tactaaaata cgattcattg atctccctct gttttttgaa
    35161 aaatttctag attttttctt gtagttcatc ttcagttaac atttatttcg tatactacga
    35221 tcattgttct gatatactta ttagtatacc gaatatttca atacgggaga agggtgatta
    35281 tgcttcaatt aaaagatata aaaaaatatt ataaagtcgg cgaaaccacc accaaagcat
    35341 tggatggtgt gtctgtcgct ttcagacaaa aagaattcgt agcgatttta ggtcctagtg
    35401 gttctggtaa aacgactatg ctgaatgtga ttggtggact agataattat gattccggtg
    35461 atatggtaat caacggaaag tctactaaag actttaagga cagtgactgg gatgcctacc
    35521 gaaacaactc tatcggtttc atttttcaaa gttacaactt gattggtcat ctaggcatta
    35581 ttgaaaacgt tgaacttggg atgacattaa gtggtgtttc taaagacgaa aaacgaaaac
    35641 gggcagaaga tgcattgcac cgagtcggct tgacaaatca tatgcataaa aagccaaatc
    35701 agttatctgg tggacaaatg cagcgagtgg ccatcgctcg agcactagcc aatgacccag
    35761 atatcctttt gtgcgatgaa ccaaccggag cgttagatac agaaacaagt atccagatca
    35821 tggaattgat ccaagagtta tcgaaagaaa aattagtgat catggtcaca cataatcctg
    35881 aactggccca tcaatacgca gatcgaatca ttgaattttc tgatggtaag atcttaacag
    35941 attcccatcc tcacatcgaa cgaccaaaag atgatcaatt taacttacgc agaacaaaga
    36001 tgagtttttg gacagcgtta aagctttcct tcaacaatat ccgaacaaaa aaaggacgta
    36061 ctttcttgac ctcctttgct tccagtattg ggatcatcgg aatcgcgatc gttctgtccc
    36121 tttcttctgg attccaaaaa caaatcgata acacgcaagc tgaaacgatg gcgaaatttc
    36181 cgattactat ttctaaggta acgactaacc agactcgtga cgatgccgga ttgggtgcaa
    36241 gcaaagcgga ttatccagac agcaaaacga ttactgcaaa agtcagcgaa gaagataaag
    36301 cacagcacac gaataagatt gatcaaacat acgtcgatta cgtaacagac atcgatccta
    36361 acttaagtaa taatatcgga tttacccgta ctacaggaat caatctttta cgtgatgtaa
    36421 atggcaaagt acagcctgtc agcttctcga atcaaaatcc tgatacggaa tctctttctt
    36481 tatctagtac gatgtcagca atgacaggtg tgggagtgtc aagtttccct acacagcttg
    36541 acactagcaa agaaaacttt ttaaaagaca attattcttt acttgccgga agttatccag
    36601 cctcagcaac agatgtcgtg ctgatcgtag acggcaataa taatactaat atcaacgcat
    36661 tgaagaatct tggatttgat gtgaaagaag acgaaaaact tgattttgat gatatcgttg
    36721 gtacaacatt caaattagta aacaacaata cttactatac aaaacttcca actgggaatt
    36781 ttatccctaa tacagattat gatgcgatgt atcagaatgc ttctgatgaa ttgaagatct
    36841 cggggatcct acgcgtgaaa tcttcttcta caatgaatct cttatctcca ggaatcgctt
    36901 atagcgatca attaacgact caaatcgtca acgaaaacaa agaatcagaa atcgtcaaag
    36961 ctcaaagaga cagtggtgta aatgtcttaa ctactgaaaa agttgacgaa aatgccaaac
    37021 aaacattgct tagttattta ggtggagaca gcttgccttc aagtatcatg atttatccga
    37081 acaattttga agacaaagaa aagatcttgg attatctaga tgattacaat aaaggcaaat
    37141 cagatgaaga taaaatcatt tatactgatt tagctggaac gatgactgaa ctgactggcg
    37201 gattgatgga tgctatcact tatgtcctta ttgcttttgc agggatctct ttagtaacaa
    37261 gtatgatcat gatcagtatc attacttata catctgtgat tgaacggaca aaagaaatcg
    37321 gtgtactaaa agctttaggt gcacgtaaaa aagacatcac tcgcgtattt gacgcagaaa
    37381 cgtgtatttt aggtatttct tctgggatat taggtgtgtt tattgcatgg ctagctacgt
    37441 tccctatcaa tagcatctta tacaacatga cggatctaaa aaatgttgct caactaaatc
    37501 ctgtccatgc gattattcta gtgatcgtct ctactatatt gacgatgctt ggcggtcatc
    37561 ttcctgcacg aatggcagcg aaaaaagacg ccgctatcgc tttgcgtgca gaataaggtt
    37621 gtgacaacca catttagatt tgagtcataa gagcgctgaa atagtagaaa acagcaagaa
    37681 acgaggaagt aatatgttcc ttgtttcgcg ctgttttttt ttaattattt tttataattc
    37741 tggtatactt ttctttcctt tgtaccacaa ctcttctggc gtatacctgt cttttccatt
    37801 tatgaatact gttccatctg cttcaatcgt tacttcagtc ccaatccaca tattacgaga
    37861 aagtgcgaga agattttttc tttttcctct tccttttttt ccaaattgca aggcatcggt
    37921 tatctcttct gtccaatgag atttcacgta ttttacttct ccgttttcaa atgtaacttt
    37981 caaaatattc gctatatttt ccacttttac tgctttagga aatgactcct ccattttttt
    38041 cactttcctt cctccaacac taagtatgcg ctttctttta gtgataagta tatcatagtt
    38101 tattctatta tcaaaaaaac gcatccattc cattgtagaa tactttaccg aacaagttga
    38161 attgttttcc tctttttcac cttttactat agataggtaa agacaactaa ggaggaatct
    38221 ctcatgacag atcaaccgta tgatttaaga aaagtcatcg aagaactaaa aacacttcca
    38281 ggtcaatatc acgaaacaga tattgaaatc gatcctgaag cagaattatc tggtgtttac
    38341 cgttatatcg gtgctggcgg tacagtaaaa cgtccgactc aagaaggacc agctatgact
    38401 ttcaacaata tcaaaggttt ccccggcaca cgtgtgaaca tcggaacaat ggctagtcgt
    38461 aaacgtgtag gtgaaatttt gcaccatgat tatcgaacac ttggtcgttt cttgaaagac
    38521 gctgtagaaa atccaatcaa acctgtgaaa gtagacaaag cagacgctcc agcacaagaa
    38581 gtcgttcatc tagctaccga tgcagacttc gatattcgca acattttgcc tgcacctaca
    38641 aatactcctg aagatgctgg tccatacatc acaatgggtg tagtcttagg atcagatcca
    38701 gaaaaaacaa tgagcgatgt aacgatccat cgtatggttc tagaagataa agatacgatc
    38761 ggtatgtaca tcatgcctgg cggacgccac attggtcact tccaaaaaca attcgaagcc
    38821 ttgaataaac caatgcctat cactatcaat attggtttag atccagcaat tgccattggc
    38881 acgactttcg aaccacctac cactccactt ggctacaatg aactatggtg tgcaggagct
    38941 ttgcgtaacg aacctattca aatcgttgat ggtatagcag tcgatgaagt gggtattgct
    39001 cgtgctgaat tcatcattga agcagaaatc atgccaaatg aaacaatgca agaagatatc
    39061 aacacgaact caggaaaagc aatgccagaa tttcctggct atactgggga tgctaatcca
    39121 gctgtacaag tagtgaaagt caaagcagtt actcaccgaa aagacaatcc aatcatgcaa
    39181 acaacgattg gtcccagtga agaacacgta tctatggccg gtattcctac agaagcaagt
    39241 attcttgcct tggtcgataa agctattcca ggaaaagtag taaatgtcta caatcctcct
    39301 gcaggtggtg gtaaattgat gaccatcatg caaatccgta aagaaaacga agcggatgaa
    39361 ggtattcagc gtcaagcagc tattcttgct ttatcagcct tcaaagaatt gaagacagtc
    39421 attttagtcg atgaagatgt tgatattttc gacatgaacg atgtagtttg gactttcaac
    39481 actcgtttcc aaggagataa agatatcatc gtgatcccag gaatgaggaa ccatccattg
    39541 gacccatcag aattaccaga atataatcct ggctctattc gtttccgtgg gataagtgca
    39601 aaaactatct ttgacggtac agttcctttc gatatgaaag aacattttgt acgtgcaaaa
    39661 ttccaagaag tagaagattg ggaaaaatat ttgaaataat gaatgatctg caactgtttt
    39721 gacatcataa aaaggagtgc ggaaaatgga acaattggca caacggaaga aaaaaatcgt
    39781 gattggtgta agtggcgctt caggcaccat ttatgccatc aacctagtga agaaactaaa
    39841 agaatatccg atgatagaaa cacacggaat catcagtcca tgggcaaaac agaacttaaa
    39901 gctggaatcc gacttatcac taactgaatt cgaaagcctg tttgattacc attattcaaa
    39961 caaagattta ggtgctgctg tcgccagcgg atcatttttg accgatggaa tgatcatcgt
    40021 accggcaagt atgaaaacag tcgcaggtat ctctgttggt ttaggcgaca acctgattgc
    40081 acgtgctgct gatgtaacaa tgaaggagca acgaaagtta gtcattgttc ctcgtgaaac
    40141 gccattaaat gccattcact tggaaaactt gactaaatta gcacgactag gtgtgcaaat
    40201 cataccacca attcctgctt tttataatca gcctcaaacg atccaagatc ttgttaatca
    40261 ccatacaatg aaacttttgg atcaatttga aattgtaaat gagcattcaa aacgttggca
    40321 gggtgattaa tatggaaaaa gaaacgatag ttgaagtaac caaactaggt ttcacgatcc
    40381 aagctgctgt taaagtaatc ggtaaagact tattgatcac tttaacaggc ggagatacac
    40441 cacatatcgg aacagtcact acattttctc gtgatacaga gatgcaaact gtacgtttcc
    40501 ctagccacga tggtcggttc cataaagacg atgtcttagc cgaaaaaata gctgtgatca
    40561 tcaaaactgc cgttccggga agttgtacga tcacttccgg tatccatgtt gaccatatct
    40621 ccaatgcaca aatcaacgcc tcttttccga tgtcagaaga gttaggttac aagattttag
    40681 attggttgga aaaaatagat ttccatatca aagaaccagt ttattataaa gatggtgaaa
    40741 aaccattatg aaagaagagg ttgtgaaatc agcgttatga cctgagtatg agagaaaaaa
    40801 atggaaaaat agcttctcat attttgccgt ttttgagcta ataccgaggg acagctgatt
    40861 gaacgccgtt tatcaagagg ttgtgataaa gccgcttcgt ttcgagtagt aagaaaaatt
    40921 ttgtaaacat gggtttccac atttttgcat aaatttgact tactaccgag aaactggctt
    40981 ttgaacaccg tttatcaaga ggttgtgaca cgtcttttgt cacaacctct tttatttttg
    41041 cttcactgta actgctacaa tatcaccgat ttcttttccg atgtttttac gaatatcttt
    41101 tcgtagtcca aggatgtagc agactgaacc atctggattt ttcacgccca tattcacgat
    41161 actgccttca tacggcacat tgtcaaaagt tgcttggact ttaactcttc cagcaccgaa
    41221 ttcttttctt atatcatacg gaaaaataat atatgccccg cccttgccga cttcggaagc
    41281 atagattttt gattcaaaag aataaatttc cctcatttta tttctcctat tttttacatc
    41341 tagtatagca tagcaaaaaa aagaaggaac tgtgacaaaa gtcttgtcgc agttcctttt
    41401 ttcgaataaa cggtgttctc ctgccaactc ctcggtcaca agtcacaata gtcaacaaac
    41461 atgagaagct gttttttgaa attgctcctt gtgactcaga gttaaacggc aggctcacaa
    41521 cctcttcctt aaacggtgtt caaaatatta ttcgcctttt gcttctttca ctaattttgc
    41581 gaatgcttgt tgttggaatt cagcagctaa ggctttcgta cgttgttctt gctctgcttt
    41641 gctcattttt ggattttcag tcattgcttt taccataccg tcttgaacat aagcttttgc
    41701 ttcactttcc atcgtacttt gctgtttctt cactaattca gctaacttgg ctgcttggtc
    41761 cgtacttaat tctacccatg tctctgggat tttgaatgta ttcactcggc tgtcatattc
    41821 gtgattgtta tcagcaatat tgaaccagaa tttatacatg tcgtttttgt attcccaata
    41881 agtagttttc gtcacttttt cagcatcgcc gtctgtcttt tctactttat ttgtttcgtt
    41941 atccgtacca gttgcttttg gtttttcttg tttttcattt gttcggtaaa gatacacttt
    42001 ttcttttcca ttccctaaag ctttatacaa aagcatatct gctccttggg aatcagcact
    42061 ggaaacaatt ttttctgttt ttgtttccgt tactttttcc attccaaagt gattggacaa
    42121 attagcgacg atcaaactta gtgaagcgac gaagattagt ccgaaaatca aagataaaaa
    42181 ggtttgccat gtttttttag cgaacacgtt cgttaaagca aaagcaagca agctgacaat
    42241 caaaactcca ataatcatgc attatccccc gctttcatta gaacaggttc ttttttcttc
    42301 aataaaaagg caataataaa gccaagaatc ccaaagatga tcgctacgat aaacgcggca
    42361 tggtaacctg acagtgtggc attgattgcc tgatctttat aagctaatgg cgtattatcc
    42421 aatacagatt tgcttgggat atttgctttt gtcacattcg tcaacacact gatcaaaata
    42481 gctgtaccaa tcgagcttgc gatttgacgg aatgtattat ttaccgctgt cccatgactg
    42541 atcaagttat ttggcaatgc attcatacca gaagtcgtta ccggcatcat gaccatggag
    42601 atcccaaaca tacggatcgc ataaaggatc acgatatata aaactggagt cgtttttgtc
    42661 aagaaagcaa atggtgcagt tgccgctgtc aaaatgaaca tccctgtgat ggctaaacgt
    42721 ttcgcgccgt atttatcgaa aatcgcaccc gtcacaggca tcatagcccc catgatcaat
    42781 gcacccggca acaacatcaa gccagaatgg aatgctgatt ctccacgaat attttgaata
    42841 tacaatggta cgaccatttc tgcccctacc atcgccatat ttgttacacc agctaaaaca
    42901 gctgcaatcg tgaatgtaga tgatttgaat acacgaagtt ccaagaatgg atgttccaaa
    42961 tgtaattgac gccatgagaa caaggcgatg aaaatcacac caacaactaa gaaaccaatt
    43021 actttcaagc ttccccagcc gtcatctcct acactagaaa atccgtaaag taaactaccg
    43081 aatccaatcg ttgataaaat agcggataaa atatcaatgc taggatttga caatggaata
    43141 acacttttca ttaggaagaa tgctaaaacc aagacaagaa caacgattgg cagtaccata
    43201 ccaaacaagt cacgccaatg gtagttatca atgatataac cagataatgt agggcctaaa
    43261 gcaggagcaa gtccaataac gatccctgac atccccattg ctgatcctct tttttctggc
    43321 gggaaaatag atagcatgat attttgcaat aatggcatcg atactcccac accgcaagct
    43381 tggatcaaac gaccgattag taatgtacta aaattaggtg ctgtaaagca agtaatcgtt
    43441 ccgatcaaaa agatcgtcat ggcagaaaga tataaatttc ttgaactgaa tttattgatc
    43501 agccatgctg ttattgggat catgatcccg ttgactagca agaaaccagt cgttaaccat
    43561 tgcacatcag acgctgaaat atcgaaagct ttcatcaatg taggaaaagc tgtcgtcaat
    43621 aaggtctgat tcaaaacggt acaaaatgta ccaattaata agacaacaac taaaagtgtc
    43681 cgattatatg gttttccgta aatatctacg ggttggttgt tactcatatt tctccttctt
    43741 tctgaatttt ttctgaaact actagaatac tttagtccta aattcgctat ttgtcaacct
    43801 acttgacaca taagttaata cggatataat taagggaagc aagaggacaa aaggagtgac
    43861 aaaaatggtt ggggcttccc ttaaacgttt gttggaaaat gatcaattgg ttgttggcat
    43921 cagtgaatta agtgatatcg taggtgtgtc tccacgtcaa ttaaggtatt gggaacaaaa
    43981 gggattcatt cgttcgatcg aagctgatgc gaattgtcct agaaaatatc gtttacctac
    44041 agtcataaaa gtagaactga tcaaaaaata tttagatgac ggatttactt tgtcaaaagc
    44101 tgcagaaaag gcagaaatcc gccaaaagaa aatgcaccat gtccgtaaag ttttttcaaa
    44161 agcaatcaaa gatatcgaat tgatcgacga acgctatacg attttacaaa tcggtaactt
    44221 caaagaagag aatgctaaga tgtacatcat tcatgacaac gagacagacg aattaactta
    44281 caagctcctt cctgtcgatg aaaaagctga ctacgaacag ttgttaaaag aactctaaac
    44341 gccactaatc tcctaagtac caagcttttt aataagtaga tgctacataa atacttgaaa
    44401 aaaggcctgt ttgaacataa gaatatccga acggtgatct gcgtttcttt catatagaaa
    44461 ggaattctcc atcactgttc ggatattttt ttattttttt cggttacttt cttctaatac
    44521 atctgttagc caatttgcat attctgtttc ccgattgatc gcatgcgcta aaatcaggta
    44581 gtgtccgtaa ttttcatgtt tttctttttc agtaggaaag atcgtttttt ttcgctctaa
    44641 tagatgaagt cgtttttctt catgaaggtc acgctgctgc tgaataattt ctactaatgc
    44701 cggatcattc acgtctttga cgaaatacaa tttcagaaca aattcgtctc gattaaccgg
    44761 tagttcattg gtgggtgtat gaatccactc tgccaattgt tccttccctt cttctgttaa
    44821 ttcataaact ttcttttcca atttttcacc tgtgatctct acttgatgct gaatgattcc
    44881 ttgctcttcc atttttgcaa gttcaggata aatctgacta tgttttgctt gccaaaattc
    44941 tcctatttca tttttgaacg attgattcaa ttcatatcct gtcatcttct tcttacttaa
    45001 taaccctaac aaaatatatc gaagtgtatt ttttcttgcc atcagttttc cctccttgac
    45061 aaatctttaa atccattcta tcataaatga gtaatcgaaa acatgtagtt tattacatgt
    45121 tttaatttat aaggagatgc ttaaacatga aagaatttaa agaattggaa gattttattg
    45181 gaactcactt tatctatacg tatgacaatg gttgggaata tgaatggtat gccaaaaatg
    45241 accatactgt tgattaccgt atccatggcg gaatggtcaa aggccgttgg gtaaaagacc
    45301 aagaagctga tatcgttaaa ttgacggacg gcgtattcaa aatcacttgg acagagccaa
    45361 cagggacaga cgtggcattg gactttatgc caaatgaaaa gaaacttcac ggaatgatct
    45421 ttttccctaa atgggttgaa gaacatccag aaatcactgt tactttccaa aacgaacata
    45481 tcgcagaaat ggaagcagct cgtgaaaaat atgaaactta tccaaaatta cttgttcctg
    45541 aatttgctac gatcacttat atgggtgatg caggtataga caatgaagat gttattagcg
    45601 aagaaccata cgatggaatg ccagatgata tccgtagcgg aaaatacttc gatgaaaatt
    45661 ataaacgagt aaaataaggt tgtgaaagag aggttgtgaa atcagcgttc tgacctgagt
    45721 attagagaaa gaaacggaaa aatagttcct catgttttgc cgttttttga gctaataccg
    45781 agggtcagct gattgaacac cgtttatcaa gaggttgtga aatcagcgtt atgctttgag
    45841 taataagaac gctagttaga aaatagcttt tcatattttc taggctagtg ggcttattac
    45901 cgagaagcag ccgtttgaac accgtttatc aagaggttgt gaaatcagcg ttttgacctg
    45961 agtattagag aaacaaatgg aaaaatagtt cctcatattt tgccgttttt tgagctaata
    46021 ccgagggtca gctgattgaa caccgtttat caaagattgt aacaactgca tattcacaca
    46081 gttaaattag tgacttcaaa atgaaataat gctcccagca aaaaattagg ctgggagcat
    46141 tatttcgtta ttctgttcat caaaaatcag cgttttgatt ccatttcatc acaagttcct
    46201 cctcatttac tgcttcatct ttttgctgtg tttgaattgt aaaaccttgt gaaagataga
    46261 aatgaatagc tgattgattt ttttgataga ctgtcaaagt cagtgtttta ttggtttctt
    46321 ttattttttt cattagttgc gtaccgattc tttgttgccg gtattccctt ttcacaaaga
    46381 ttcctgcgat aaactgatca atcaccccag caaaaccaat aatttcttga tctatttctg
    46441 ctaagtaaat cactgcatct ggtaaagctt tcctaacaga ttctacttga ttctcccaat
    46501 aagttgatgg aatgaattca tgagaatcca agttagcatg cagccaaatc gatagaacag
    46561 attccagttc tttggcagac aattttgttg ttgtgcggat cattttttct ctccttactt
    46621 attcattgat tttaaaataa aaaccatttt tttgaagctc ttttacaagt tttcgcccct
    46681 caaaaaagta tatcttctct tgttttactt ttctaatacc aaaagaaaca gcaactttag
    46741 gatcatcagc tgaaacgatt cgataagttc caccaggcaa ttgatccagc ttgactttcc
    46801 catgatggtc gctttgtact gaaaacggca caccatttct agtaagtgtt tttttcttat
    46861 gtttcaaaat gaatgaacta ccatttaccg gtttccctga cgaatcacta ataataaatg
    46921 aaaaatcaag cactttttta cttaatctat actgatagat tagtcgtccg ataaacacta
    46981 acagtatgac tacagctatt atcgttcctg caagaataaa ccattgccgc atggttcttt
    47041 cctgatttcc ttttccttct tcttttttta ccgattcgtt ataaggaatc cgatgtcctg
    47101 tcactagcaa acgatgcgtg ttgatcatat acggcgtaca tgtaagcaag gtaactaagt
    47161 cttctccttc tgaaatcgtt agaacagacg tgtcatctgg cagtaccact tgtatatttt
    47221 taacttgata agccaatttc tcccccaaaa cagtcaaaat aaacgtgtct ccgttttcta
    47281 aacgatctaa ttcggtaaat aaccgtcgat taggtaaacc gctgtgagca gagatcactg
    47341 aatgcgtcga atttccacca agcgggaaag aggttccttg caagacgcct gctccatttt
    47401 caaggatcct accattgagc cgatcataaa gtgaaatatt taattggatc ttaggtatat
    47461 tgatacttcc gatcagccat tcctctaatt ggctggatgt tgtactttca tttctgttct
    47521 tttcattgaa aggatcagta ccaggattga atccttggtc agttaatcgt tggtttttct
    47581 cctccatttt ctttcgctgc acttcaattt cagctgcggt ccgtttttgt acttgttcga
    47641 tacgtttttg atcaataaaa ctatttaaag aatccacata aaatggatat aaagcgatca
    47701 gtaaccctac gacgatacat attaataaaa acaaacgaaa caaaagtcga cgagactgtt
    47761 tttgcttact ctgcttcaca tgtgtcctcc cttgcaagtt tttttgttct ttcttttatt
    47821 atatgggttc aggaaaaaaa tagaaaatga aagccgatga ggttgtgaaa aagctgtcct
    47881 gcatcaagta ataagtacag cccaaaaaaa tagctactca tattttttgt tgggttgggc
    47941 ttattaccgc agatgcaagc ttttgaacac cgtttaagga agaggttgtg aaaactgcgt
    48001 tatgctttga gtaataagag cgctagtcag aaaatagctt ctcatatttt ctaggctagt
    48061 gagcttatta ccgagaagca gctgattgaa caccgtttac cgagaggtca tgaaaaagct
    48121 actttgtttc gagtattaag aaaaattctg tttcaaaaca aggagatgca acaaaactta
    48181 tgtcgcatcc tctctcctta gaactttcac ttatgttttt cttgtaaaat tcataaatat
    48241 tttcatgaat tttctaattt cttgcctacc tctcgcatag gatatatgat gaatttatct
    48301 aaagtttgca aaggagttcg acaattgaaa aaatatggcc catttttagc aatttttttc
    48361 attgctttgg catttctcat gcctcattta ttcacacata aactaatttt gggtgctgat
    48421 gccccattcc attacaatcg gttctatgat gccgcgcaac aaattaaata tggggatttc
    48481 cattattttc cttcccttta tggattccag caaagtggca ggatcgtgaa tgccgtttac
    48541 ggcccatttt tcgcttattt acaaggattg atcgtgttgc ttgcaggtag ctggtttcat
    48601 tatcagattc tttcaaattt cattctttat cttatttcag gattttctat gctgatttta
    48661 ctgagatatg tcaatgttcg aaattgggta agtgtaccag tagccgtttt attcatgagt
    48721 acgtattcta ttcaatactg gtctatcaac caaggattca ctagctgggg gacttgtttt
    48781 tatcctttat gtatgatccc tattgctgat ttcgtccttc ataaaaagtt ccctgttatc
    48841 aaagtcgctg tctcagtggg acttatgaca cagatccatt tactgtcttc gatcatgtta
    48901 gctttgatgt atatcccttt ttatctttat tactttttta accagactga aaaaggaaaa
    48961 gcactgcttc aactgattaa gtcggtcttg ctttattttg ttctgacagc aaatatttgg
    49021 gcaggattag ctattgttta cagtgggaat aagattcttc ctccctttgt taacagagaa
    49081 atgagtcaaa aggcgataga tctggatggc agttattggc tccattaccc taaggccttt
    49141 cctatattga tattatcagg ttttttgctt tttattttct ttcaacaaaa gaacacctta
    49201 ttccaaaaaa tcgtgttgta cacaagtctt gttttctttt ttctttctac tagcttgatt
    49261 ccatggacga cattgatcga aaaaaatgtg ccttttatta gtttgatcca gtttccattt
    49321 cgatttttcg tgccatttac gctattgctt ctactttacc ttgccctttc actgaaccag
    49381 tggtctgaac aaaagtggtt ccgtctttta agtatatttg gcattcttat tttttcagca
    49441 cagacgatcc agaacttata ccagcatctg gaaaagtggg aaaatgaaac atttgtcagt
    49501 cgacatactt atctattcga tacgccggaa gaagcaagga aaacattctt cagcaaagat
    49561 atgtctacca gcttgttcgt tttccaaaaa accacacctg actatctgcc aatctataag
    49621 gagacaaaag acaataaata cgaccggtat aacgaagaaa tactagaaaa cgaaacaact
    49681 tttataaaaa cacatccagg cggtcttttg acaatcaagt ggaaaaacac tggggacaaa
    49741 actgttcata tccctgttat cgtctacgat cggactgtgc tacagcaaaa tggaaaaaca
    49801 ttgactgatt atgaagtaac agatatcggg accccaatcg tgaagcagca aaaaggaatc
    49861 aacgagctca cgcttcatta tcaaacgcca atctatttct atttcattct ttctcttact
    49921 ttgattggct ggtttacctt gctatgttta tttatttatc atagatacaa gcttttacat
    49981 gcttaggcaa aagggataaa tacatccgat caaaaaactc tccaaacggt ataatcgttt
    50041 ggagagtttt attttaatca gtttttttat gttatatgtt atatttttta ttcgttcaca
    50101 tctaattcga tttccacccc gtagtgatca ctgatgattg gactatcgat cccatcaaaa
    50161 atccgttgat attttttaac ctgcattcct tcagggacga aaataaaatc tatacgcaat
    50221 ttttctgtat tttgttccca accatctatt ttcttttcca cagtagctgc ttttcctttt
    50281 tcattcgcga caacatacga atcttgaaga agaaggcaac tttctcttac agtataataa
    50341 ccttgagagt ctactggatt attgaaatca cctaggaaaa aaagtggtac gcgagtttcc
    50401 aaaaagtagt tttccaagtt tttccactca aaataaaagc cacttttttt atctgtccac
    50461 caagaaaagt ggcagctcga gacaaaaatg tcctgatcat ctatctttgt tttcccaatc
    50521 aagatcttgc gtgtctgata atcttctttc ttttgaaatt gggagacggt aaggacctga
    50581 ctttccaatg tttttttcgt aagcagtgca tttccttctt catatttatc ataaccgatg
    50641 tggctcattt cccaactcca aaaatactct tttccgtgtt cctttaaaag ctgaactaaa
    50701 cggtaggcaa aattatcttt acggataggt acttgattct ttaccggaca gaacttcatt
    50761 agcttcgcag gttctacttc ttcagattcc agtaattggt tgatttcttg taaagcaatc
    50821 acttcataat cttctaacag gatcttatct gctaattctt gcaatttttt ctctggttct
    50881 ggctcaagcc agctatgcgt gttgagtgtc atgaatttca ttggttttct ccttgtcttc
    50941 atttcgaaac aaaagggttg tgacaaaatt tttgtcacaa cctctccagc aaatagtgtt
    51001 ctcctgctaa ctcctcagta ataagctcaa tggaccagga gctatttttt gtttggctgt
    51061 ttttatcact tggtgcaggg cagctttttc acgacctctc cactaaacag tattcaaact
    51121 gctgcttctc ggtaataagc ccaaccaaac gaaaaatagg aggagctatt tttgtttggc
    51181 tgttcttatg acttgatgca ggacagcttt ttcacaacct ctccttacat tttaatggag
    51241 ccgatcactt taccagctgt cactgtacct aattgcttga tcactacttc ttctacttta
    51301 tcgtttgtaa atacgatcat gatcgttgga tctttttctt cgttttggat cacatcaaga
    51361 tccatctcag ctaatttcgt tcctgttcct acttcttggc cttctttgac agcaatctca
    51421 aaagctggct gattcatttg gactgtatcg attcccatat ggatcaaaac ttcgatacca
    51481 tctttcgttt ccagcccaat tgcatgtttg ctagggaaaa tacttgtcac ttttccagcg
    51541 atcggcgcaa caacttctct tgatgttgga ataacagcaa agccgtcacc catcattttt
    51601 tgtgagaata ccggatcttt tacttcagat aaaggaatca cttctccaga agctgcggaa
    51661 actagttctt gttctatacc taagtattgc ttactacctg cttgtccatt tcctgtagaa
    51721 accatttctg gctctggaat ctctgctcct gattgcagca gatcttcgat atctgatttc
    51781 aagacatctg cttttggtcc ataaactgct tggactccat tgtctttgac gatcaatccc
    51841 atcgcccctg ctcgtttcca ggcttcttca gtccctactt tttctcgatc atttacactt
    51901 acgcgtaacc gagtcataca agcatcgaca tctttgatat tttcttttcc tcccagcaaa
    51961 tgaatgatct ggaccacttg ctgatctgct gttcctgttc cgctgttaga tacaacggtt
    52021 tcttcactgt cattgtcgta atttccgtta cgtcccggtg tagcaaagtt gaattttttg
    52081 atcaagaaat ttgctaagaa atacgtaaca acaccaaaag cgatcacaca caacacgaag
    52141 ttgataagat ctccacctag acccgctttg atagctaacg gtgtccgagt cagcaattcg
    52201 atattcccaa atgaatggac ccgcaatggc aagatatctg ccatcgcaaa tgcagcccct
    52261 tggatcactg aataaatgac atataatggc acagcagcaa acataaacat gaactccaat
    52321 ggttctgtta cacctgttag aaagacagcc aacgctgctg aaaaatacat tgatttatat
    52381 cttgctttct tatcaggatc gacattacga tacatcgcaa aagccattcc catcaagata
    52441 cctgaagaac caatcatttg tcctactttg aaacgagccg gcgtccagtt atgcaacaca
    52501 aactcatatt gcgacatatc ccctgcacct ttaagattca ctaaatcagt ggcccaagcc
    52561 aaccataacg gatcttgccc aaatacttgt gtccccgcct gtgcgcctga taaaatctca
    52621 tacgatccgc caagctgtgt atagttgata ggaatcgtca gcatatgatg caatccaaat
    52681 ggcaatagta aacgttctaa tgttccaaat aaaaacggtg ctagaatcgg tgcgctttct
    52741 tgtgattctg caatccataa accaaaatta ttgattccag cctgtacgtt tggccacacc
    52801 acagcaagaa tcaatgccac gattgttgac cataagataa caacaaacgg aacaaagcgc
    52861 tttccattga aaaatgacaa agcatccggc aattttctat aattatagta cttattataa
    52921 gccattgccc cgacaaatcc agcgatgatc cctacgaata ctcccatatt caaagctggt
    52981 gcttccaata cacttgtaaa aaatccttta accatgatct tcgtaccgaa cagagtgtgg
    53041 gtaaatgcat cttcattcgc aagcatgtca cttgtgacac caaagatagc cccagtgatc
    53101 cgattgatta aaataaatga gatcccagct gcaaatgctc cgcctgctct ttcttttgcc
    53161 caacttcctc ctattgctaa agcaaataaa atatgaagat taccaataat tgcccaacca
    53221 atattttcaa ttactccgcc cgttgtgaca agcggcgtcc aatcaggatt gatcaaggga
    53281 attgatttcc ctatactgat catcaaccca gctgccggca taactgctac cacaaccatt
    53341 aaagcctttc caaatttttg ccaaaactca aaactaaata tctttttcat tccgtttagc
    53401 tcctttacgc aatcggtttc gttaaacgta ttatagcgtg cgttttcttt tttgtaaatg
    53461 ctttattttt tatttttctg tctataccat tctataaaac ctataatacg tgtgttccct
    53521 tctataattt tctcctaaaa atttattttt ttaagctttt ttctatgaaa tattttcttt
    53581 tgtctattga cttgtgcaat cggttgcgtt tattatgaac gtataaaaca gctcattagg
    53641 aggagaaaaa tgaaacagat caaacgacta tttgctattg atccatggaa aatcagcacg
    53701 acacaattag ataaaaaaaa tcttcgactg caagaatctt taacaagtat tggaaacggt
    53761 tatatgggga tgcgcgggaa ctttgaagaa acttactcag gggaccacca tcaaggtact
    53821 tatttggcgg gtgtctggta tcccgataag acacgtgtcg gctggtggaa aaatggttat
    53881 ccagaatact ttggaaaagt gatcaacgcc ttgaacttta tcgcgataga tatttcgatc
    53941 aacgatcagc tgatcgactt ggcttctttg gaaccagaag acttttactg ggaattagat
    54001 atgaaaaatg gtgtattatc tcgtacattc acaatcacta cttctactaa taaagtacgc
    54061 atttccttcg aacgttttct gagcattgtc aaaaaagaat cagcttatat ctatttaact
    54121 atagaaatgc ttgaaggtag cggaacagtc aaactcgtat caaaattgga tggaaatgtt
    54181 caaaacgaag acagcaacta tgatgaacat ttttggaatg agattgatcg tggaactata
    54241 gaagaaatcg gctatttgac gactaaaact attccaaaca actttgggat tgaacaattt
    54301 actgttactg cagcaatgcg ccatttcgtt aatggaaaat cagtcatccc tgactatcac
    54361 gaagatactt tagcattaca tggttgcttg tctgcagaat tatctcaagg tgagacatgg
    54421 tcagtggaaa aagaaattat cgttcttact agtagagata ttccagaagc gcagcaagca
    54481 gaaaaagctg tctcagaatt aacgaaccag acaaacaatt atatccaagc aaaagaagag
    54541 caaacagcgg cttgggcaga acgatggaag cttgccgatg tggtcatcga aggagacgaa
    54601 gaagcacaac aaggtattcg attcaatttg ttccaactat tctctactta ctacggcgaa
    54661 gatgaacgat tgaatatcgg ccccaaagga ttcacaggag aaaaatacgg cggagccact
    54721 tactgggata cagaagcgta tgctgtccct ctttatcttg ctttagccaa acctgaagta
    54781 actaagaatc tgctgaaata tcggcataat caactgccgc aagcaatcca caacgctcag
    54841 caacaaggat taaaaggcgc gctttatcct atggtcacct tcactggtgt cgaatgccat
    54901 aacgagtggg aaatcacatt cgaggagatt caccgaaatg gcgcgattgc ctatgcaatc
    54961 tacaattata cgaattacac cggcgatacg gaatatttga aaaatgaagg actggaagtt
    55021 ttagcagaaa tcgcacgctt ctgggcagac cgtgtccatt tttcaaaacg agcaaataaa
    55081 tacatgatcc acggtgtgac cggcccaaac gaatatgaga acaatatcaa taacaattgg
    55141 tatacaaata cgatcgcagc ttgggtcttg cgttacacgc gagaaaatta tttaacttat
    55201 caaaaagaag ctgctatcac tatcagcgaa gaagaactag ccaaatggaa agatatcgca
    55261 gagaacatgt acttcccagt tgacgaagaa ttaggaatct ttgtccagca tgacacattc
    55321 ttagataaag atctcatgcc tgtatccgat attcccacaa gcgatcttcc tctgaatcag
    55381 cattggtctt gggacaaaat ccttagatct tgcttcatca agcaggcaga tgtactacag
    55441 gggatttatt tcttcaatga tacttttaca aaagaagaaa agcaaaaaaa ctttgatttc
    55501 tatgaaccaa tgactgtcca tgagtcttcc ctttcgccaa gtatccattc gattttagca
    55561 gcagaattag gaatggaaag caaagctgta gaaatgtacc agcgaacagc tcgcttggat
    55621 ttggataatt acaataacga cacagaagac ggcttgcaca tcacttccat gactggtagc
    55681 tggttgtcga ttgtccaagg atttgctcaa atgaaaactg cccatgatca gttgagattc
    55741 gcaccatttc tgccaaaaac ttggaaagct tattctttcc atatcaatta tcgcggacgt
    55801 ttattgttca tctcagtcac agatgaacaa gttactttcg agttattaga aggttctcct
    55861 ctagaaattt acgtctatga acagtcttat tctttagcgg atcgtctaga aataacgcta
    55921 agaaaggagg aagcaaatgt ttaaaggggt attgtttgat ttagacggtg tcattaccga
    55981 tactgctgaa ttccattatc gtgcttggcg aaagcttggt caggaaatcg gcattacgat
    56041 cgaccacaca ttcaacgaac agctaaaagg cgtcagccga gaagactcac tctctttgct
    56101 tttagcttat ggcggaaaag aacactcttt ttcaaaggaa gaatttgcag aattagcgaa
    56161 aagaaaaaac gattattatt tagagatgat ccagacgatc gaaccaaaag atgtcttccc
    56221 cggggtcgtg cctttactgg attctttaaa agaagaaaaa atcaagattg ctcttgcttc
    56281 tgcaagtaaa aacgggccat tcctacttga aaaaatgggt cttacacctt actttgatgc
    56341 tattgccgac ccggcagaag caacaaacgg aaaacctgcg ccagatatct tcctccttgc
    56401 agcaaaagct gtcggactaa aagcagaaga atgtatcggg atcgaagacg cgcaagccgg
    56461 tatccaagcc atcctctcaa gtggcgctca accaattggc gtgggacgtg ctgaagacct
    56521 tggagaggag atcccgcttg tccctgatac gacttttctt acgatcgatt acttgaaaga
    56581 aaagtggcat gaccatggat aatccagaga tctccgtcgt accagttcca gagactgaaa
    56641 taaagaaaat cacattgaag aacgactact tagaagtcgt tcttctcaat tacggtgccc
    56701 gcctgcacca aatcttcgca ccagacaaag aaggaaaatc agaaaatgtt ttattgtctt
    56761 acgatcgttt cgaagatgtt ctaacagaca aaagcttttt tggagcaact gtcggacctg
    56821 tagccggaag gatccgggat gcttcttggg gtgagcatag attggagaaa aactgcggat
    56881 cacaccatat ccacggtggc acgaaaggct ggtctttcca attttgggaa gtagaagttt
    56941 tcaaaactcc atcatcaata ggtgtggtct tttacttaaa agatgaattt tctacctatc
    57001 caggaccaat cactgctacg atcacttacc gtttaacaaa aaacgaatta gagatgacaa
    57061 cctctgctag tagccttgtt gaaaccatct gcaatccgac caaccatgcc tacttcaacc
    57121 tttcaggaaa tggaacaaga gacatctatg aacatcagtt aacggtcttt ttagatggtg
    57181 tgcttgaatt agatcaagaa aaactgccta ctggaaattg gacaaaaaaa gaaaaactgc
    57241 caatcgactt tagaaaatcc ccaacactgc aagagatcct tgcatgttat ccagatggac
    57301 tagatgatgt atttcttttg catcatccta ggctttccaa aacttcctta caattattcg
    57361 agaagcattc tggtcgccaa atgactatag caacttctaa taaaagtatg gtattatttt
    57421 ctacgactgg attcgaagct gatttctctg tcaatggaaa acagatgcat tcaaactacg
    57481 gattagcaat cgaaccgcaa gaaatccctg atatcgttca tttccccaaa tttggatcga
    57541 tcaacctcca tcctggtcaa gaacggatca gtcagacgat ttatcggttc tctgcacaat
    57601 aacaagagaa aggtgttttt atcatggcta ttaccgtaaa agatgtggcg aaaaaagccg
    57661 gtgttgccac ctcgaccgtc tctcgtgtca tcaacgatca tcctagtatt tccgagacaa
    57721 caaagaagaa agtccgaaaa attatggatg aactaggtta tgttcctaac atgactgccc
    57781 gcaatctagg aaaacgcatt tccagtgcca tcggcgtaat cttaccccct cttgattcaa
    57841 aagagcggat cggtaaccca ttttatcttg agatcatgga agcaatcaac gaagaagcgc
    57901 ggaattatga tatgactaca gcaatcgcta ctgctaaaaa ttttgaattg ctgttagaga
    57961 acgtccagcg tatgcattta caaaaacaag tagatggttt tattctagtg tattcagata
    58021 gtcaagatac tgtcattgat tatttatacc aaaaccacat ccctttcact ttgatcggac
    58081 agccttatca tcatgagaac gaaatcgttt atgtagataa tgataaccag cttctaggta
    58141 aacaagcaac agaatttttg atccagaatg gacataagaa tatcctgttt gtgacaaaca
    58201 cgactcatga aagtttgtat ttcgaacgat atttcggtta tcaaaaagca atgatgatgg
    58261 ctggtcttcc tgcgttatcc agtgtagtac tagagcatcc ggaggattat ctgtcctttg
    58321 agaaaacgtt gaaagaaaac gaagccacag cattggtggt cattgacgat atcttcgccc
    58381 ttcgcacgat gcagttggcg caaatgtatg gctatgtcat tccagagaca ctctccgtca
    58441 ttagcttcaa caactcgatc ttctcaacat taacacaccc ttaccttaca agtatcgata
    58501 tcgatatctc cgaattagga cgtgtcgcta tgcaaaagct gcgcgaattg atccatgaag
    58561 aattgagcag tggcgtacgt ttggtcatcc ctcatcgctt gatcaaaaga gagacagtcg
    58621 ttcctttaga aaacccatac taaatagctg actcactaaa tacgctgacc atttatccta
    58681 tggtcagctt tttatgtaaa agaagatact acttctaaca cattgtttat ctgtaaaaaa
    58741 gagcgtggga caaaagtaaa gaacactttt gtctcacgct ctaaacacgt ataaacggcg
    58801 gaagcagaag caactccttc ggaaataagc tgaaattcac aaaaatttaa aaagcaattt
    58861 tcttgagttt cttcttattt cttggagtta aacgcttctg tcccagcctc ttttttcctt
    58921 ccttcaattt tttacacgtc gacgattcaa taaaaaaccg cctaatattg taaagacagg
    58981 tgcaagaatc gagaaaaagg cgaatggcaa gtaatgcaac gcgctaactt tcatcgttcc
    59041 cataatgaat gtgccgctga ctccccacgg tacgagagaa ttgacggtcg cacctgaatc
    59101 cgctagtgtt cgtgtcaaat aggtttttga taagccaacg tcatcaaaag aacgcttgaa
    59161 tgtttctcct ggaagaatga tggacagata ctgttctcca acgatcagat tgattccgat
    59221 acagctcaag gcagtaaacc cgactaaacg agaaggtcgg tccatctttt cttttaattc
    59281 ttgaacgatg gtatcaacga tcagatattt gatcagtaac ccacctaatg ccaatgcaag
    59341 taaaatcaaa ctagcagaac ctaacatact catgatcccg cctcgagaaa gcagttcatc
    59401 tagctttgga tcaggtgtat ttgcgacata accattcatc aagatgtctg ctgcttttcc
    59461 gaccgtcaaa cttttctcat ggataaaaga aagaacgaga gcagctgtcg atcccgctag
    59521 taatgtaggg atagccggaa tttttttgat tgccccccca aataaaataa ctagtggaat
    59581 caatgtccaa ggagagatcc aaaagctcgc tttcatgttt tggatcattt cattgatact
    59641 agctagatcg gctgaatgac tgttatgtcc taatatcgta taaaaaatca acgaaaggac
    59701 gaatgctggg aaatccgtat aacgcatacc agcgatatgt tcgaatagat taactcctcc
    59761 aatacccgct gccaagttgg tcgtatctga taaaggcgag cagttattcc ctaaaaaggc
    59821 accggaaacg actgcgcctg tagtcattgc atcattgaat ccaagtaaat gaccgatccc
    59881 caaaaaagca attccaatcg tcgaaatcgt tgtaaatgaa ctgccgacag tcactccgac
    59941 aattgcacaa acaagaaatg ctgtcggtaa aaagaaacgc acagaaacaa gtttaaatcc
    60001 ataaaccata atcgtaggga tggttccaga taaaatccat gaagcaacta agacaccaat
    60061 caaaagaaaa atcaggattg gaatgatccc tggagtgatt cctttgatga tcccgtcatg
    60121 gatctcatcc catgtgaact ttttaaatct gccataaaac aacaaacaca tgaaagctgc
    60181 aaggatcggg atatgtggcg agagctggaa tccgatgatc agtactccta ggagtgccaa
    60241 caacacgatc aatacagcga tactttcttt taaagaaata tttttattca tcgtcgatct
    60301 cctatttcaa atgaaaaggc cctgccatga aaaaactatt cacttggcag gacctcctac
    60361 taaatcagcg acaaaacgtc ggctgaaaga cttatttttt tatttttctt ctaaactttt
    60421 ttctacctca atcccccaag aatctttctt gaagtgattg atgatcaatg gaataacgaa
    60481 catgaccact gtgatagctg ctactaataa tgcatcactc aatgtcgctg tacctaatgt
    60541 agcaaatacg acaacgatga tagagaagat cagcatgcag ctgactaccc aagctaatcc
    60601 gtttccgttt ttaccaattc ggtaaggacg ttcgaattct ggatgtttct tacgcatttt
    60661 aagcaatgaa acagcaatca aaatgtacac gatacaataa ataacagttg tagcatttgt
    60721 aagtgtcaag aatacagcac ttacgtcatc cattacacca taaagcaaag caaataatga
    60781 aataacgatt gattgtgtta gaacgacatt tctagatacg ccgtatttgt tttctttatg
    60841 gaatccgaat tttggtggaa ggaatccttc acgagctact tggatgattg tttttgatgg
    60901 tccagtaacc caagctgata attgtaaaag cacaccaata aataccatga agctgaagat
    60961 atttccgatc acttctggta agcctaggat ttgacagtca atcaagatag gctgcgtgat
    61021 atttgctaat tccatttttc catctggtac gacatttgct acaagcatcg cattgatgac
    61081 attcaataaa actaatccga tcaaagcgat aaatacgcct tttgtataat tttttgttgc
    61141 gtctttcaaa cgaggcatgt aaacagaact catttcgatc ccaacaaaaa taaatgtgat
    61201 accagctaag tatttcaatg aatcaatatg ttccaagtca gggaaagctt ttgaccatga
    61261 aaagtcacct agatagccgt ttgagactag tccgactttg aaggctgcca aaacacctaa
    61321 aacgaacatg atgactactg ggatatatac ccctagccat acaccgatgt tcccgccgac
    61381 ttttgccata tcgaatttca agttcaagat cgtgatgatc cagtagataa ctaaaataca
    61441 acctaaaacg aaccagtgat tattgccaag ttctacatta ccaaatgtgt ttcctaacaa
    61501 tggtcctaaa gtagaagcga ccattaccat acctgggaac atttgcaccc ataatagcca
    61561 tgcaacgaca aatccccatt tgctgcccag tgctgttttt acccataact gaggaccgcc
    61621 ttcttgagga agcatcgtgg aaagctcacc ggaaaccatt gatatcggac cggcaaaaaa
    61681 caaaactgca aaaattgaat aaaaaatcaa tgtccaaccg actgcggcta acgtaggaat
    61741 actccgaacc gttgcacaca gtgccattgt cagaccgata aaggtcccaa gacccatttt
    61801 acttacttca gatttactca ccgttgacac tctccttgat tttttggata aaataacggt
    61861 gtctttgaag tagtttcagc aataaacgaa acaattcagc gaatatttga ggggattctt
    61921 tgagtttatt gcttgaaggg tttcttcaaa gacaacctca aaacaaaggg atcgaagagc
    61981 ttaggtctcc ccttgctctt cagatccaaa catgcgtcag aaacagttag tattcaagct
    62041 gttttctaac atgattacct tgcttatttt gcttcgcttg ccaataattg gtctgcgtag
    62101 attttttcca atttttcttg aagagctgct ttgatttttt cagcatattc ttcaaagtgt
    62161 tcttctttgt tcatgtatgg tgtcattacg ctggcacgca atacagttac ttttccggca
    62221 cggttccatt cttcatctga gaatcctagt tggttcacaa attgtaatgg gctgttgcca
    62281 tagtctggga tagcaaagtc agtatgtgaa gttaagaact cattaccgta aatgcttcct
    62341 ttcacgtatg aagaataatc atatacgtca tggttcaatt tattcattgc aactaagtca
    62401 tcgttgcctt tttctttgaa tacatagtct accatattga aatctggata agttaatgga
    62461 tgaacttcga tttctttgtc tcctacttta aatgacaagt cattcaagaa gttgtagaaa
    62521 cgatgtgcac cttcgattga tgcacccatt aatttaccat atcctgtgac attcaaaggt
    62581 aagacatggt gtgctgccca aacgctggct gctgttgccc ctgcttttga accttccaag
    62641 atataagccc caagtaatgc tgggatatct gcgccttttt caaatacata tgtcgcaaag
    62701 taagagataa cgtctctcat gcggatatct ttgatgacga taccaccggc agaatatgga
    62761 acatagccca ttttatgtgg gtcaatcgtt acagattctg cttcttcgat tgctttatat
    62821 gcactgtgta cttcttctaa gatataatct ttgttttctg taaagacatt gtatttgtaa
    62881 tgaacatctt ttaaatcttc aaatggaatg aagttgttgt cttcgtctaa gaaaatcgca
    62941 cggccgtatc cgccataagc agcatctacg tgtaagtaga agtaaatacc gtctttttct
    63001 aatacgcgac gcaatgcaac gattttatcg ataccgtcga ttgctccttc ttctgttgat
    63061 cctacaacac cgactacacc taggattggt gttttttcag ctgctagacc acgaacgatt
    63121 ttttcaagtt cgttgatgtc catgcgatag ttgtggtcaa ctggcactgg aatcacttgg
    63181 tctaaaccga taccgatgat gtcggcagct tttagccatg aatagtgttt agtttgtgga
    63241 accaaccatt ttcctaattt ttctaaatgt tttccgctac gtgctgagtg agctttgatt
    63301 tcgtcgattt tttctgggac gctgtctaac agattcatga tttcttctgt tgacaagttc
    63361 attaattccc aatcgctttt tccagcaact agttcaggtg tcacttcttt cattgcaagc
    63421 ggcaatgatt tgatgttgcg ggcataccaa agtccttcta agtttgctaa agaaccatca
    63481 gcaacgatgt ggccccagcc atctttatag ctcattaatt ttgcaaattc cattcctact
    63541 tcttcttcca tttggcttgt tgcaggagaa gattcatagg caacgttatt accattccat
    63601 agcatagcaa aattgtacgc tagtaaagat ggcatcaatg tttcagagtt catatgaccc
    63661 cagtaacgtc cggcattatg ccaaggaacg gaatgggtac gcatccgcgc tgaaatttct
    63721 gatagaacat cctttgtttt attcacagtg tgttcaaaac tagcactgct tttttcttct
    63781 ggcgtaataa taggcatgtc ttgaggcatg tagttttgac gccagcctaa atgttcatcc
    63841 accaattcat tcaacaaagc tttatagatt tggccgttct cagctttgtc cccaatgaat
    63901 agggcattta ggtttagatc tttcgacaat gattcactca tagtgaaacc ctcctaaaaa
    63961 aatatttaaa ttttgtcgag ccctacatta cacctgttct tctattctgt aaactaagtt
    64021 ttggcctgat ttttaatcat attttaatat gtatcaatta tccgaattgt tcacactttt
    64081 gaaataatta aaaaaaacga gggaatttac aaatgtaaac tccctcgcaa agattgtatt
    64141 aacgacaacc agcgttctat tttaggatgg gtttcaaaat tggaatgttg taatagtatt
    64201 tccctttttc aaggtaaaaa cttactaaat tctaatcaat tactttggcc aaaaagtaat
    64261 ttttcttacc ttttcgaata accacaaact taccatcgaa ttcatcggat ggatttatga
    64321 caaaatttaa atcggtaacg cggtcaccgt taatacttat agctccgttt gaaacatctt
    64381 cacgtgcttg acgtttagat ggttcaattt ttgtggaaac aagcagttcc acgatatttt
    64441 caggtgtgct tgaaatttca acgttcggca ttttaccgaa tccttgcgcg atttcttccg
    64501 catttagttc tttaatattt ccagagaaca atgcttgcgt tattttttgc gcttctttca
    64561 agtcttcttc actatgcaca aatcttgtaa cttcttctgc caaacggcgt tgtgcttcac
    64621 gtttctcagg ttctgtctct acttttttcg ctaagtcttc gatttcttct tgagacaaga
    64681 aagtaaagaa tttcaagtat ttcactacat cgcgatcatc ttgattcaac cagaattggt
    64741 agaactcaaa tggtgaagtt ttcttcggat caagccaaac ggcaccgcct gcagtttttc
    64801 cgaatttcgt tccgtcagcc ttcagcatca atgggatcgt taaaccgaac gcttctgctt
    64861 ctggtccttc taattttcgg attaggtcta atccagctgt gatatttccc cattggtctg
    64921 ctccaccgat ttgcaattgc acatcgtatg ttttatgcag atgcaaaaag tcgatagatt
    64981 gcaggatttg gtaagtaaac tctgtaaatg agattcctac ttccaaacgg ctggcaacga
    65041 tatcttttgc taacatcgtg ttgatgttga agtttttacc gtagtctctc aaaaattcaa
    65101 gtaaagagat ttttgacaac cagtcgtagt tgttcacaaa tgtgatattt gcatctttac
    65161 caaacaattt tctcatttga ttggaaagtg cgtccacgtt atgttgcact tgttccatcg
    65221 tttgcaacac acgttctgtt ttgcggccgc ttgggtcgcc gatcgttcct gttccgccgc
    65281 caatcagaat atatggatga tggcctgcca attggaatct tttcatcatc ataaatggaa
    65341 tcaaatgtcc gatatgcatc gaatcaccag ttggatcaac gccgcaataa agtgaaatgc
    65401 tcttttcttc aacgagctcg cgaagtcttt cttcgtttgt ttgctgatta atggcgtcgc
    65461 gccaagttaa ttcatcaata atattcattt tactgacctc cgtgtagttt ttttatgaaa
    65521 gcaggaacct gctagcatgt gtaattaatt atttcttcag gataggatag gaaataaaaa
    65581 aagtcccttg gcatataagc caagggacga aatctcgcgg taccacccaa tttgtatgtc
    65641 tagatatcca acatacctct cgaacattta acgctgtcgc gtggcaatca ctgccaaaga
    65701 ctcctgaaat gtaattcgct ttaaagcatg tactggtttg cagcgaccac cagctttctg
    65761 aaacattggc tttaacaact acttcgtttc gatcttcgtc ttgttattat taatatgtgt
    65821 ctatcataga gcgcaacttt ttctttgtca acagaaaaag gatatttttt ttaaattcct
    65881 cattttttct tttttgaatc cgctctaatt ccgaacattt tattttcaat tattgttaaa
    65941 agaaataact ttttctgtat tttttctgca atttatcgag aagtcacttt actttgcctc
    66001 ttattctttc ttcgttacaa taaggaatgg gacaagtaaa aaaatgaaaa agcaagggac
    66061 gaggtatatg gaaaaaaagc aaaaaattat tttaggagcc acttctgctt taactatcgt
    66121 tattttaatt ctaagtttgt tttttgtcat ccgatcatct acaaaaaaag aaccaatcat
    66181 tcctgaaaaa aaaataacag aaaaagcaaa agaaccgaca gatgataagc aacaactagt
    66241 tactcaagca aaaaatctgg ctcaaagcta cgattatgac caagcgattg cgttattgga
    66301 aaaagatagt aagaacggat ctactgaaac acaacagctt cttcaaacac taaaaaagga
    66361 gaaagaacaa ctgatcgact ggtctgatcc tactcagatc tctcatgtct ttttccacag
    66421 cttgatcgtg gacccgcaaa aagccttcca ctctcaacag gcacaaggat acaaagatta
    66481 tatggtgact gttgaagaat tcaaccgttc gatcgaacaa ctttatcaaa atgattttgt
    66541 tttagttaat ttgaatgatt tgatccaaaa agacgaacaa ggaaatcttt cctttaacgg
    66601 gcttgcgcta cctgaaggaa aaaaaccatt ggttctttca caagatgatg tcagctatta
    66661 tgaatatatg gataattccg gttttcctag ccgattggtc gtatcaaata acaatgaaat
    66721 caaaaatgtc tataaagaga aagataaaga agaaatcggt gactttgaca tggttcctct
    66781 gatcgatgcc tttgtcaaga aacatcctga tttttcttat cgaggcgcaa aaggtacctt
    66841 ggccctgaca ggttacaacg gagttttagg ttatcgaaca tcaaaatctc aatatggaga
    66901 caatgaaaaa acaaaaaaag agattaaaga agctaaaaaa gtggcggaac agttgaagaa
    66961 agacggctgg agctttgctt cccatacatg gggtcacttg aatatgactc aagcttcact
    67021 agaagatgta aaaaaagaca atgaattgtg gcagcaagaa gttgcaccta tcctaggaaa
    67081 aacaaatatt ctgatttatc catttggtgc agacatcagc gactggcagc cttattcagc
    67141 agaaaatcaa aaatttgctt acttgaagag tcaaggtttc gatattttct gtaatgtcga
    67201 tgcttctaca ccagcttggg gacaattagg tacggatttc tatcgaaatg ctcggatcaa
    67261 tatcgatggc attcgttttc aatctgattt agacggaaaa aatcctattc ttgatccatt
    67321 catcaatgtc catgatgtct atgacaaaga agcacgcgaa tctgcttgat tttacgtcat
    67381 ttatgaacca aaaaagccga actgacattt tatcgtcagt ttcggctttt ttatgcttta
    67441 tttcttcttc ggtgcgattc ccttgatcag gacttctgtc cattctgctg tatatggaag
    67501 cagttttgcg tatatctccg gcttagaaat tccttctacc attgcttgaa aatagaggat
    67561 caagaactca tccgaatatt tcaaatccac ttttccttct ttccgccctc gatggaaaag
    67621 atcaagcatg atactgaaac tttcttgcgt atacgcatcc atcgcgtcag aaaattcttt
    67681 tttttctttt tttgtatagt atgtcatcaa atcgatataa aattgtttgt tcactcgatt
    67741 gagataacgg attttgtttt cactcatggc aatcagtgtt tcttcaaatg gaagattttc
    67801 cgcaatcaac gctttcgctt cttgccctaa atcattcata aatgcaaaaa atacttcata
    67861 aatcagccct tccttgctgc caaaatattt aaaaatcgtc gctttactta cctgagcgtt
    67921 ctcagctacc ttatccattg tcactccagc ggttcctatg tctgtgttca tcaagtcaaa
    67981 agctgcttgt aaaatctctt tctttttctc ttgtgctctc ttttcaaaac cgttcatttg
    68041 tagagcctcc cgtaatttta aacttttata atatatatag ttcaaattta ttctgaggtt
    68101 tattataact atctattgag aaagtatcaa gctagcaatt ccttgtttat gaattcattg
    68161 acagaaattt ataaaaagaa tattatgtac taaaataata aaaaaaagtt ttataaaaag
    68221 gtataaaacc tttttattaa actatttaat cttgtttagt atatattttt agaaaaagga
    68281 gtggggtttt tatggcagaa atcgtcaaag tcacacattt gaaaaagagc tttggtcgtt
    68341 tcgaagcttt aaaagatgtc tctttcaccg tacattcagg tgaagtcgtt ggatttatcg
    68401 gaccaaatgg ttctggaaaa tccacgacga ttcggacact tttagggatt ataaaaaaag
    68461 acggcggaac ggcaacgatt tttgggcaag atgtatggga agatagttta tctatccatg
    68521 aacgtctttc ttatgttcca ggcgatatct ctttgtgggg aaatttgact ggaggagcga
    68581 tcatcgatct cttcatgaag cttcatggaa aagggagtgc tcaaaaaaaa gatgaactga
    68641 ttcaacgttt ctctcttgat cctaagaaaa aagcaaaaaa ctattcaaaa ggaaatcgcc
    68701 aaaaagtggg cttgattgct gctttggctg ttgattcgga tctctattta tttgatgagc
    68761 ctacttctgg tttagatcct ttgatggaaa cgattttcca agaagaagtt gaaaaattga
    68821 aagaacaggg caaatccatc ctactttctt ctcatattct cagtgaagtc gagcgactag
    68881 cggataaagt cgtgatcata cgcgaaggaa cactcgatga agaaggaaca ctcgatgaat
    68941 tgcgtcattt gactcgttcg accatcacta tagaaacaga agcagagaat agtcacttag
    69001 cacaattgaa cggtgtccat gactttgtgc aaaaaggtca cctcgctcaa tttgctgctg
    69061 ataacgaagc tttcgatgtg attttagctg aagcgtccaa attaggtgtg aaaaaatttg
    69121 aatctattcc accgactctt gaggatttat tcatgagaca ttatgaagga tgaggaggaa
    69181 gcgaaatgac tgataaattt tcacgctggt ccaccctttt ttctcaaaac cttagccgtg
    69241 actggaaaaa gatcctgata tggctagtcg gtgtcactgc tttttctggt ggttttgtcc
    69301 ctgcgtttga agaattgact tccggacaag gattagctgg attatacgaa accttgcaaa
    69361 acccggcaat gattgcaatg gtcggaccaa ctccagcttc gaatgctgct gagtatactt
    69421 taggagcgat gtatgcaaat gaaatgttgc ttttttgcag tttgtttgct gctgtgatct
    69481 ctgttttaca cgtggtgagc caaacgagaa aaaaagaaga acttggtctg attgaactta
    69541 ttcgttcctt tcgagtcgga cgtcaagcaa actctttagc tgtcatcgct gaaagtattc
    69601 tgatcaattt gcttttagca atatcgatca gctgtacgat gatttttttc caagcggatt
    69661 cgatcactgc aaaaggtgct tggctttttg ggctatctgt aggtagtatg gggattttgg
    69721 ggagtgccgt tgcactgttt gctgcacaac tgatgccaag ttcagccagt tcgaatggtc
    69781 tgtctttagc gtttttaggt ggactttacc ttctacgagc aataacagat gtagctgatt
    69841 cctccctttc gatgtggaat cctttaggct ggtcttattt gacctatcca tttacaacta
    69901 acaactggat tcctttgctt tatttgtttt tgttcagtct aatcttgata atcagttcat
    69961 ttgttttaga ggaacatcga gatttgaaca ccggctatat ccccgaacgt gaaggaaaac
    70021 cgtatgctaa acgttctctt ttatccttgc gtggtttatt attctatcta aataaaggga
    70081 tgacaatcag ttggcttatc acttttggtt tgatgggggc ggcatacggc tctatctacg
    70141 ggaatatgca acagttttta gaaagtaacg acttaatgaa acagatgttt atccaatctg
    70201 gcgtctcaat tgaaaaaaac tttacaagca cgatcatggt agtcttgatt tgtctagctg
    70261 ctattttacc aattgctagc atcaatcgtt tatttacaga agaaacccac ggacgtatga
    70321 atcagctgtt cgcaacaaaa atttctagga accaacttta ttggaccaat atgttactag
    70381 ctattctatt tgctatattg gcaatcctga ttagttctgg tgcactaggg ctttctgctt
    70441 tggcttcgat gaaggatgcg aaagacatgg atctattgat gtttcttaaa gccgggttca
    70501 atttcctgcc tgccgtttta gtgtttatcg gaattagtgg ctttctattc ggatggcttc
    70561 ctcgaatcgg taaacttgct tatatctact tagcttactc ctttgcactc aattactttg
    70621 gcggaatttt ggatttacca gaatggtttt ccaaaacagc tgtccctagc tgggttccac
    70681 ggatgccaaa cgattctttt gatctttccg tgttccttac gttatcatgt atcagccttg
    70741 cactgttcgt ccttggttct attggttata ggcgaagaga cttactagaa ggataataaa
    70801 aaagcatgta caatttcatg ctagcctcca aatctgggtc aaaaatccaa catttggagg
    70861 tcattttttt atttacaagt cttctaactg ctctttatca atgatccaga cttctcgatt
    70921 ctttcttttt acataaccat tctcctctaa taatttaaat tttctagata aagtttcggg
    70981 ggtcgtaccg ataaatgcag caagttcttt cattttcatt ggcaggaaaa agtgatcctt
    71041 ccctgtcgct ttagctaagt caagcagata gacagcgact cgttcttcta ctttttccat
    71101 catcaaaaaa gttgtctgct gctgtacttt tgttaatttc tcaacgttga ttgctaaaag
    71161 tttcagacta agggcgggat aatgcagtaa gagttccgag aaatcttttt gtctcaatat
    71221 gcaaatttcc gttttttcta gtgcttcgcc aaataaagac tcatttggaa cgcctagcaa
    71281 ctggctctct ccctcatatc cgcccggctc tattactcgt aaaagctgtt cctttccgct
    71341 agcagataat tgatacactt tcatactgcc ggaggccacg atcactaatt gaggttctcc
    71401 attcggcgca agaatctgtt ctcctttttc cacatagtga tgtttgacaa gtgcgtgtac
    71461 tttttcttga tcttgctgta ctaagtgatt gaacaaagga acaaatgaaa cacataaatg
    71521 atcatgactc ataatctctc ctccttctaa acagctattt ctaataaaga aacataactt
    71581 cccttattcc aactgataat tttcttttat catagcataa acgtcaagcg aaccagatac
    71641 cagcaaatag agtggatttc tttttgtccc ttgctttatt ttccttcttt tgagacctta
    71701 agtaattgat tcctatcaat tttttaaata tttacttttt gaataatcaa aaacaaacct
    71761 tcactcgcaa gccgagagta aggtttgttt ttcgcattgc ttatttcgtg ttgtctattg
    71821 aaatttttcc gcacctagct tttgatatag tggtgctagt tcttgtaagg tttcagcggt
    71881 tatttgctca acgtgttcga tttcttgcgg atagaagaat agtttaccca tttgaaaggt
    71941 tcggtctctc atcgcttttt tcaactcttc ttgtttcttt gtatcggaca aatagtcaga
    72001 caaagctaag tggtcgtcaa gttcatgttc tggttgcggc catatgtaat aatccttgat
    72061 atcgactgtt ttgctccact ctttcagtat cgcaagcaac tggttatacg ctgcaatgct
    72121 accatatcgt tcttcgcttt tataatgttg gtacatcaaa tagatttggt attgtttttg
    72181 attcaacaaa actgctagac aggcattctc gtcttgacga gattcgcttc ggtacgcgct
    72241 ccaaaaatga ctgcgtaaat tccagccatt cgtccagctt tcgattttag gtttgctcat
    72301 gccgtacata tcaggcaaaa gtgcagctgt ctggagctga atctctttcc atttttgcca
    72361 gtgttcttta tattctttct tgatttgttc aatcttatct gttggatggc tctctttgag
    72421 ctgtttgaat gcgtagattg gtcgatcaaa caactgataa tctgattttc caagttccat
    72481 tgtttcgcct ctttccgtta tcttttgtat tctacctgaa ttttgcgata tggacaaata
    72541 gaggttgtga aaaagctgtt ctgcatcaag tcataagaac agccaaacaa aaaactgcga
    72601 tgagcatcac cgcagtttta ttgaacttaa ggttgattga tcacatctaa aagcgttgaa
    72661 aataaaatgg cactagaagc agctcctggg tcgatatgtc cgattgcacg ctctcctaga
    72721 taggaagctc gtcctttttt agctaccaag actttggtgt gttcttttgc ctggtcaatg
    72781 atttcttttg ttaaattccc tgccttcaat gcctctgtga ctggcagcca aacatctaac
    72841 atcgttttat cgtcagcttc tgcctttcct cggctttgaa tacccgctgt tccctgctcg
    72901 atcacttcgc ctaatttttc ttgagaatca atagaatcga cctcttttgt cgctttcatc
    72961 atgttcatga atgcagatcc gtataacgga ccagaagccc caccgacttt cgatatcatc
    73021 gccatagaga atactttgaa tgtatcgctg attgtttcag gatgatcggc ttgaaaagct
    73081 tcttcataag ctgaaacccc tcttcccatg ttatttccat ggtctccatc gccaatcggg
    73141 gtatctagat cactgagata ttgtttgttc tgattgattg cctctgcaaa ttgcgtgagc
    73201 cattcttgga tttcttgaac ggttagtttc atattatcac ccttttatct tgagattttt
    73261 taccatgaaa tcgtctgtac attgctttct aaagaatctt tccattgtgt ctccgtcaag
    73321 tcgatcagtg ttagagaaag accttgcata tctagtgagg tcataaaatt accgactttt
    73381 cggaaaacta cattgacgcc tctttcttcc aacagagcta aaacatcatt catgaacacg
    73441 aactgttcca tcaaaggcgt cccgcccatt ccgttgacta gtacacctgc ttcttttggt
    73501 aaattcgagt aatcatctaa aatcttagta acaagttcct ttgccagtac tttagaaggc
    73561 tgcatctttt ctcgacgata gcctggctca ccgtggatac caacaccata ctcgatctca
    73621 tcttctccta gttcgaatcc tggtttccct acttctggta cagttgctgc tcgaagcgct
    73681 agaccgatcg tcttagttgc ctgtacgacc ttttctccca gttctttcaa ctcagctagg
    73741 gaagcaccgt ttcttgctgc atcgcccacg attttgtgta caaggacagt acctgcaact
    73801 ccgcgttttc cagcagtata cgtactattt tcaacggcga tatcatcatc tacgatcaca
    73861 ctttctactt caatatcgtc catagcagct aattcctttg ccatatcgaa gttcaatgca
    73921 tcccctgtat aattcttaac gatcagcaaa actccttttc cactatcggc ttccttaata
    73981 gccgtctgaa tctgatctgg agttggagaa gtaaacacat caccaagcac cgctgcactt
    74041 aacatccctt cccctacaaa cccggcatgg gatggttcat gtccgcttcc tccaccagaa
    74101 accaaaccaa cttgttccgc tttctgattc ttggctacaa cacgggaaga ttctacacga
    74161 tgaacaagtt ctggatagct ttttactaat ccttccagca tttcttcgac aatattgctt
    74221 ggatcattca tgattttttt caatttattc ccatcctttc tttccggcat tttgtgcttc
    74281 tgttaagatt tgctgagtat catctgttat accggcagtg atggctgctg caaaagctcc
    74341 ttccactaaa ggcgcatcca ccagatgata acgttgctgc tgctcttctt ccaacatgtc
    74401 ttttgccagt tccgagttca ataccgcgct accgatatcc gcaaaaacaa aataactagc
    74461 tgcatcgctt gattcattga ctgcttctac gattttcatc gggtctgatc cgatctcgcc
    74521 atttattccg ccgagagaaa aaatttgcac ctcttcggat ttttgcatct gctcaatcat
    74581 ttctttaata ccatctgtta ctttttgact atgagaaata agcaaaatac tttttttcac
    74641 aagaatcttc ctttctttta catagttgct aacgattggt ttcgctttca ttaatgaaca
    74701 attcaagtat ataataaatt tctaattttg ggaaaatatg tgtagtgctt cttgaagttt
    74761 gttatacttt aattaaaaga gaggagtgat cgaatgatta caacaacaac gaacagtgta
    74821 gagggaaaag ccgtagtagc ttataaaggg atcgtttttg gtgaggtcat tactgggatc
    74881 catgcattta aagacttgga ggcggggttg cgaaatatct ttggcggccg ctcaaaaagc
    74941 tatgaaaacg aactaatggg tgcaagagaa gaagcacttg ccgaaatggc cgaacgtgca
    75001 aaagcattag gagctgatgc gatcattggc gtaaaaatgg actatgaagt attaggcagc
    75061 gacaatggca tgctgatggt cacatgtagt ggaacagctg tctccacgag ataagtaggg
    75121 gacatctgtt ttaataacta aagagagatg ggacatgtag tggcactcaa gaattagatt
    75181 tttcagtcta acttcgaggt actctacctt cccatcctct cttttttatt tctttttgcg
    75241 gatgattccg taagctgctg cgactaacac acccgcccct gctaaggaat aactgacaga
    75301 agctgttttt tcatttgttt ttggcaaagt ctgacttgtt gatttggatg gctctgtcgt
    75361 ttgctgaact gtttctgtcg tgcttccaga ggtcactgat ttttctcctg ccgaatgcaa
    75421 aatatctttt attcgttgga aactagctgc taagtcagct ttttttgctt caaaatcatt
    75481 agcaactgtt tgtgcttcgc tgatctttcc gtggattgct tgactggccg ctgtgatatc
    75541 cgcttgagtt tgacttagct ttccagaagc tgtttgagca acctgattta attgctgatt
    75601 gaattctttt gcttgttgga tcttcccgtc aagatctgtt tggacagctt ccgcttttgc
    75661 tttcgcttcg gcaagctttt tctcaagttg tgcacggtca tttcccactt tatttttaag
    75721 atcagctaaa tcttgatcga ttgctgcttg gtcttctttc aatttgtttt ttgcagcttc
    75781 taatgcttct tcgagttctt ttcttttatt ttccaagtct tgcaaatgat cgatttggtc
    75841 agaagaggta gaactattta ttgatgtatc ttctgaagat gaaatcgttt ctcctgaatt
    75901 atctgtcggt acattggaag tcatttctgt ttccgaggca ccgttttcag caccagaaga
    75961 gcttatggtt gttgaaggtt ctgtttgagc aggttcagaa gtttccgcaa aagctgtctg
    76021 tcccaataag aaaatactgg aaacagcaat tggccagatt aacggcttca ttcttttttt
    76081 catcactttt cccatcctta ctacttttta actaatttct tattataagc aaaaatgttt
    76141 ggaagaacca taaacacaac aggctgtttg tctaaaaaac ggtgcatctt ttattttttt
    76201 gtacgttccg ggcttttcca tgtcccgctt ccataaccta aaatcgtttt gactgctgga
    76261 atgaaagtcg tcacgatcgt tatcgcgttc actatccaga acaaaagcat atatagtggt
    76321 gcgaaaagaa ggtatttcaa ttttcttcgt cgatcatcta caatcagcga agctagcaac
    76381 tggaaaaatc ctgcgaccat ttcaaagcag atgaacacaa aactgaatgt aaaagtaata
    76441 taaatctgtt cgtagtttcc ttgatataca taatgcccga ttaatccagc aaaaagaact
    76501 acggaaatac aaaagaatat tgaccagaca atactcaatg tttgatcaat gaagatgatc
    76561 gttcttccaa tatgtttaaa aggatggagc atcacttttt tgaaattcgt cagccagact
    76621 tctgttccac cttttgccca acgttttctg tgtcgatata gcatcttcaa cgtcacaggt
    76681 acttccatga aaaagataat ctcaggagca aaaacagata accagtcatt taactgatga
    76741 tcccaagcaa tactgatgtc ttctgtcgct cgatcttgtc tgaatccgcc cacatcgatc
    76801 aaggcttctt ttcgatacat cgtatttgct ccactgtacg cataaagacc accgaaaaca
    76861 gctgactgtg ttcgtttaat gatgcccacg atacttgaga attcaaccgt ttgagatttt
    76921 gcaatcaatt tggtacgatt ttggacatcc atatttgcag tgaccgcagc aatatgtctt
    76981 gcaccagggc gaatgaaata attcacatac ctaatcagtg catctggctc cggtaccgtg
    77041 tctgcatcat tgcttaaaat caatttccct tttgcaaagg caagtccgat attaaacgcg
    77101 tgggcttttc ctttattttt ttcgatccga accacacgaa gattagcgta ttttttcatc
    77161 agtctagcta atatttctgg tgtttggtcc gttgaaccat cgtctgtcac taatacctca
    77221 tagttgtgat aattcaattt cgtcatcaaa tactcgattg tatattcgat cacaatttct
    77281 tcattatggg ctggcaccat gatcgtgatg aacggttcga cactcaaggg aacatctacc
    77341 cattcttttt gcttatgttt gtataaaaac acataacacc agacaccaat aaaccataca
    77401 aatccgccta aaatcggata agaaacgaga aaaaaataca taatagacaa acaagtatct
    77461 aagaataaat tacctgtatg ggtgattgag atcatttcag ttccacccca ttttctttat
    77521 acaaatctgc aatgaatgtc gtatctagat ttttctcttc ggagacagaa taaaaacgga
    77581 ccgtttctct ctcttctttt gttccaaaac gttccgtata cacttcttca agtaattctt
    77641 gtcttttttt caatttttca tcttcatatt caaaagattt atttactttt ttgtatagat
    77701 ttcgattgtt ccacctagtc aatacaaatg aggtaatcag gaaactgaaa aaaatcaata
    77761 caaaaaagcc gattaagaaa tacagcattt tcttttctga taaaaaagcg tacaaggaaa
    77821 aatccttggc tctttctggt ctcgttaatg ggaaaaagac ccatataaaa ggaagaacaa
    77881 cgatcatcca tcctaaaaga gccactaacg tttgccaaat ctttaaccag taattacctt
    77941 ttgaaaaata cttatctttc accaaaattg atgcaacttc ttctcttgtt acttttttca
    78001 tatcctcacc tcacgttttt ttgttacgac gtaggagttt accatacatt tcatttcttt
    78061 tcacataaag tgttcctaaa tttttcctaa gaaaaagaac aaaacatttc tcatcagcaa
    78121 atgaaaaata ttttgttctt tttatcagtt gttcttttta ttttttatct cttaattatg
    78181 ttgctctttc caatacgaca atgcttttca ttcctctaga tatcgccgtg tacatttgtc
    78241 tgcgtcttct ttgctcatct ccatcgtttt caaatggata taagattaca tgatcaaatt
    78301 ccagtccttt tgctagactc aaaggaatga tttggcagtt ttctaatcca tatgaatttt
    78361 ttttaatcga ttcttgtagc gtttgggttt cctcttctgt ttgggtgata actgccgctt
    78421 tttctccttt tagagaaacc aaaatctcag ctagtatttt caacaattct tcagaggatc
    78481 gaaaagagcg gtattcgggt tcttttcctt gcggtcggat cgatacgatg tcgatcttct
    78541 cttgatccac agcataggtt ttgaaaagct ctgtgattgc tccgctagaa cggtaactat
    78601 ttctaagatc ataccgatgg atcggcagat ggtagtcgtc gaaacaacgc ataatatcag
    78661 caaaagtagt ggaagaatta aagattgcct gattctcgtc acctactaaa gtaaagtgag
    78721 tttttggaaa taattcgatc aatagaccta attgtgccag ggtataatct tgtacttcat
    78781 caatcaatag atagcgaaat gctggtacat ttaccttttc aacaagtaaa tgacgaatag
    78841 ctaatataat gactgcttca tcaacagtac gtgtgggttg ccaagcataa gctgagccat
    78901 atcgtttttc ataaattctt tcaaacaact gatgctcatc cacccatgcc atttcttcga
    78961 tttgtctggt tatttttcga tatttttttt gtaaaagttt ccttgcataa gctacaatac
    79021 tttgttccga atcatcagaa atcaatttac cgaataattc caactgccta tcttctgtca
    79081 acgagagtac ctgattctgc acagcaggac tttttgcttg tttcaaaaga tgattcttcc
    79141 attcgctcat cagtgccttt ttcgttgctt gaagcctatc gatcaattta ggatgagcag
    79201 gaactttctc atatattttt tcgatcgttt ttttagaaag gactgttttt ccatttttag
    79261 taagtccacg gataaaattc ggatgatcta aaaacaaagg atctgattgt tttagattat
    79321 cgataaactt tttgctacgc aaacgttctg tctgctccga tacattttct cccgtgatac
    79381 gtttgaaata agcctcttca ccttctattt cctctgctga aagctgtgaa accagctgta
    79441 tgatggttag attcagtgga tttctttcac ctaatgatgg taggacattc gaaatatagt
    79501 cgataaaccg atgattaggt gatagaatca gcaagtcatc ggatgtcatc gtatctcgat
    79561 ataaatagag cagatacgca atacgctgca tgatagcaga ggttttacca cttcctgcta
    79621 cgccatttac caagatattt tgacttttca catcccgaat gattgtgttt tgttccgatt
    79681 ggatcgtagc agtgatagcc ttcatttcat tggtctcatc ttggcctaag acttctaata
    79741 atacgtcatc ttgaatagct acagacgtat caaaaaactt gaccaaacga tctctttcca
    79801 aaagaaattg tcgtctttct ttaataaccg tatcgatttt attttgacga accgtataag
    79861 aagatggacc aatcatgtta ttgtaaaaaa gttcggcaat tggtgaacgc caatcataaa
    79921 caagattttc atctgcatca tctgtgaaat ttgctgtacc gatataaaag gattcttttg
    79981 gctcattatc cagaaagtct acaacgactt ttccaaagta gggacttttc aataaacgtt
    80041 cgatctttgc tagctgattt tctgcgtttt tctgtttgat attcatctga tcgatttctc
    80101 tatttttcat ttcaatcatc gaaaaagtat ccaggttatc taagtaactg tcaaaattca
    80161 atcgaagctc gccagccatt tctttcaacg actggtttcc ttctattttt gccgtatcca
    80221 tcgattcccg cagttcgttt tttttatcaa ttagcttttg atacacgttc ttcagatatg
    80281 cttcttctaa ctgtttttgt gtgttgacca tacacattct cctctttttt taaagtggtg
    80341 gaaccgatta gtttacctct tttaagagtc gaatgcaagc tttttaacga gtatcatttg
    80401 ttaggatata tcagttcttc aggtcggaca gtttgatata aagaaaatgc accatcaagg
    80461 ttttttacgt ggtagccaga ctgcttcaag attctttccg ctagatagct acgtaatccg
    80521 ctatgacagc tgacgatata ttcttgttgg ctgtctaatt catttaatcg gtcccgaagt
    80581 tcattcaaag ggatatgttt ggcttccttg aatttgccct tttccaattc ttctgctgtt
    80641 cgcacatcta ataaaatttt tccttttgct agttctgtcg gcaattcatg ccattgtacg
    80701 gtttcactaa gcccttctgc aatgttcatt gctgcatatc ctagcatgtt tactggatct
    80761 ttggctgagc caaatggcgg tgcatacgtc aattctaatt ccggtaaatc gaagatcgtc
    80821 aaatgccctt tgattgctgt tgctaaaata tcgatccgtt tatccacacc ttttgcccca
    80881 acaccttgtg caccataaat ctcgccagtc tctggatgga agatcaactt cagtaaaata
    80941 tctgttgctt ctggataata gcttgcatga tcttttcctg atacatgaat gacttcaaaa
    81001 gacagttcgt tttctttggc tgttctttca cttaaaccgg tggatgcggc agtcattcca
    81061 aacgttcgta taattgctgt tccaataccg ccttgatttc ttcgagaaat tccggaaatc
    81121 gtgtccgcaa cttgtctacc ttgacgattg gctggtgaag caagagaaat aagtgcatct
    81181 tttccagtga tttgctgttt tacaacgata gcatccccca ccgcataaat atcaggaata
    81241 ttcgtttgat aacgttcgtc tactaggata cccccgcgta tgcctaattc gattccagcg
    81301 gtcactgcta gctggttatc aggacgaaca ccaatggata aaataactaa atcagcaggg
    81361 atggtacgcc catcatccag tcgcaatcgt ttcccgtggt cttcaaatcc agcgacagca
    81421 tgagaagtaa tcacttctac tccttgatga gacaattctt tttctataaa agctgccatt
    81481 tcttcatcca gtgttggaag aatatgtggt gcttgttcga tcaccatgac ttctaaacct
    81541 cttcttttta ggttttctgc catttccaat ccgatgaatc ctgcaccaac gatcacggca
    81601 cgctttggct gtttttctaa tgcatgcatc actttatcga tatctggtac atttctaata
    81661 gaaaaaacat tgtcggcttc tgttatccct ggaatcgatg gaacaactgg ttttgcacca
    81721 ggagataaaa ccaatgcatc gtactgttca atgtgttttt gaccctcatg tacgacttct
    81781 accgttttgt tttcgggaaa gatggctgtc acttcatgat ttggacgcac atctaaacaa
    81841 aaacgagcgg ataatgattc tggcgtttgg acaagaagat tttcccgttc actgatttct
    81901 cccgaaagat aataaggcaa gccgcaattt gcaaaagaaa catacggtcc tttttcaaaa
    81961 acaacgattt ctgcatcttc cattaatcgg cgaagccgtg tagcagcaga cattccacct
    82021 gctacacctc cgacaataac gattttcatc ttatttccct cctactgttc gatcaaacca
    82081 ttgattcatg ccaccacgta cattcactac atcataacca gatttcttta attctttagc
    82141 tgcttgttta ctcctcatcc ctgattgaca aatcacatag acggtctttt ctttgtctcc
    82201 atcatatctg tttatacttt gtaatggaac atttttagct ccttttatat gcccgccccg
    82261 gtattctgca ggtgttctaa catcaagtaa cgctggattt tccaaaagct tttcctttaa
    82321 ttctgggact gttatcgatt ttattgattg aaatagcaaa ttcattttct gcacctcatt
    82381 tacattttta taaatacctc atggggtata ttaaacagga gctttattaa tatgtcaacc
    82441 agaatgactc ttcatttttt tcactacttt ttatatttgc ataaaatacc gataaggggt
    82501 attatctaat tataaaaata gaggagaatg tgttatggag attgataata aaaatatcct
    82561 gaaccgtttg aaacgtacag agggacaaat tcgtggtatc caaaaaatga tcgaagacga
    82621 aaaagaatgt atggatgtca tcactcaatt aagcgctgtt cgttctagta ttgatcgcgt
    82681 aatgggcatg atcgttgcag ataatctgaa aaattgcttt gagaaacctg atagtaatcc
    82741 agaagaacaa gcggctaaac tagaacaagc gatcaagatg attattaaaa agtaaaggaa
    82801 tgatttcaat gaaagtcgtt ttccatattg atgaattaga aaaatggtca gaaacaggga
    82861 aaaacgtaaa aaacctgata aaagcttctc cagaaacgac gattgtcgta tctgtaaatg
    82921 gcatcgcgat taccggttat ctagactctg ccaatgcaga attcttagat ttgcaaggag
    82981 tcgtttttca cgcttgcgcc aatgctatgc gtgctaatca tatttcagaa agttctttac
    83041 ctgaacaagt aatcgttgta ccagcaggtg tccttgattt agttgaactg caatcccaag
    83101 gttatgctta tatcaagcct tagtcagtag aggttgcgac agaagtgatc agcttcaaga
    83161 aatttcggct tatttttcga agaagctact tctggaaaac cgtgaatcaa aggttgtgaa
    83221 aacgctgtcc tgcatcaagt aataagaaca gccaaacaaa aatagcttct catatttttc
    83281 gtttggttgg gcttattacc gcagatgcaa gcttttgaac accgtttaag gaagaggttg
    83341 tgaaatcagc ggtttgacct aagtattaga gaaaaaaacg ggaaaatagc tcctcatatt
    83401 ttgccgtttt ttgagctaat accgaaggtc agctgattga acaccgttta aggaagagat
    83461 tgtgaaaaag tcgcttagtt tcgagtatta agaaaaattt tgtgaaaatg gatttctaca
    83521 tttttgcata aatttggctt aataccgaga aactggcttt tgaataccgt ttaaggaaga
    83581 ggttgtaaaa tcagcggttt gacctgagta ttagagaaac aaacggaaaa atagctgctc
    83641 atattttgcc gttttttgag ctaataccga aggtcagctg attgaacacc gtttaccaag
    83701 aggttgtgag cctaccattt aactccgaat cacaagaaat aatttcaaaa acaacttctc
    83761 ctgtttttgg ttcggttggc ttattatcga gaagtagcta ctgggagtct atttatcaaa
    83821 aaaaggaatg cgacataggt cacacccctt ttttattttc tttgaaacat ctttcggtac
    83881 tcgacagcat acaagacaaa agattgtaaa agaccgtaag tgatgacggc aaaaatgact
    83941 ctcacccaca gcgttggtaa ttctgggaaa agcagcaaaa ggatcatgcc aacatagatg
    84001 acagcagtcg ctactttgcc ataccacttc gctccactta atttgatatt tttagatagc
    84061 ccgattaatc cagctacaaa cataaagcct tcttttatca agaatagacc aaacaacagc
    84121 caaagccacg gtcgatacca tgccatagac aaaatcagaa aaagttgtgt caatttatct
    84181 gcaaacggat caagcacctt ccctaagtct gttacctgat tatatctccg agcaatgacc
    84241 ccgtctagat aatcagacaa acctgagaca acaatgaccg ctcctgctat ataaaatgac
    84301 tgtctcagca caaaataaag ataaatcggc agcaaaaaaa tacggaatat cgataaaaga
    84361 ttcggaatcg tttgtatttc tttacgccag tctgtgctta atttcatttt atcgccctac
    84421 ctcctcagca ctcttttctt tttattttag cttacacggg gaataaaacc aatgatttca
    84481 ctgtttttat ttttctttac agacactgat attatgagct aatttgagat aatcacttgc
    84541 tgttttcatc gtttactctt ctttcttcct gtcgtttgcg catttctttt actagtactt
    84601 tatgagcttt ttttgatcct cgctctaggt cacgctgccg tttacgtgtt ttataatcga
    84661 taaacagact gtctaaatcg taacctgtcg ggtacagatc ttctgctgaa cgcaccagac
    84721 gaacacgctg acgaggcacg tggattattt ttttgtctaa atatacatca atcgtatctt
    84781 cacctatatc ttcataaact aacgcttctt tttggtattc attgacaaat atccgatcac
    84841 cttttgcaaa gagctgacgt tcttttttat tctccttcct atttgtaact gctgtcttag
    84901 gaagaaattc ttttttctgt gtccgatagg ctttttccgc caagtaacgc tctgcttgat
    84961 ggatcaattt catcgacata tccattttat gagcaatcca caaagcttgg ctttctcctg
    85021 tttcttccaa cccgcaactg atatttagga cgaagtgctt cccgatcgaa agccatagca
    85081 gccggcacaa aatcttcatg atctccggcg aatttcttga tttctccata atgggtcgtg
    85141 gcaatgatca atgccccttg ctcatacata gattccatga ttgcgatcgc tagtgcagcc
    85201 ccttcatttg gctctgttcc actgccaatc tcatctaaaa gtaccaacgt attccttttt
    85261 atctttttca aaatagcagc gatgttttgc atatgaccag aaaatgtact caacgcattt
    85321 tctaaatttt ggtggtcacc gacatcgacg aaaatctcat caaagacagc aagctctgtc
    85381 ccttcttttg ccggaacttg cataccgaac atcgccatca aagtcaataa accgactgtc
    85441 ttcaacacga ctgttttgcc tccggcattt gctccggtga taatcaagcc tcgatagtct
    85501 ttaccgattt caacatccaa tggtaccgca tgctcaggta aaaatggatg tctgccttgc
    85561 ttgataatga tatgttccga tttattgatt ctaggtgtgc ttccattgat ttctcggcta
    85621 aattttgccc gagcaaagat gatatctaac accgtgatcg tttcgatcaa taaatcgatc
    85681 acttcttcgt tttctgcgat agcaccagtc aatgccgcta ggacttgata ttcttcactg
    85741 atttcttcag cttttaacaa ctgatagtgt tcattcaatt tagaaatcac agttggttca
    85801 ataaaaaccg tcgttctttt atttgattca tcgataatcg ttccatctat tttattttta
    85861 tagctggctt tgataggaat cgtatagtat tcgccttttt gaacaatcat tgcttcttgg
    85921 atcatttctt tgtttttcgg atgacgcaag aatttcagta attttgactg gatttctttt
    85981 tcgattagtt gtaattgttt gcgtacttta cgcaaattac gtgacgcgtc gtcactgact
    86041 ttattatttt ttattttctg gtcaatcaac tcttctacat ttatcaaatc aggaagatgt
    86101 ttgctataag caaacaacaa gggtgtctgg tattgattct tatcaaaaaa ctttgtgatc
    86161 atccgactgc ttctaagaaa atccgcatat tcgatcaaat cggttggctg cagaatcaac
    86221 ccttttttga cttgttctgt cagtgcatcg atcctcggca accccataaa tggaacatgc
    86281 tgactgcttt ctaagatcaa gcgtgcttct cttgtttctt cttgacgatc caagacagtt
    86341 tgtaggtttg tcgagaccgt catatcgctg attcgttttt tgctatagtt tccaattgct
    86401 cttgcttgga tttccttttt gatccgatca aattgtaatt gactaatcat ttcgttgtcc
    86461 atattctctc cttttcttga agagatacct gtcccaaaat aaataagggc ctagagataa
    86521 ataaaaggat agaacacagc ttaaaaaagt catgtcctat ccttattaga atacaaagat
    86581 attgttttcc tgacaggtac cgtttcataa gcacaccaaa taaactttgt ttattggcta
    86641 ttcgacttac tgattagata ccagctacac tcacaaaaca taccccattc ttctaggtct
    86701 tatttatttt ccacttaact atagcaagac acattttggt tgtcaaactt tagtatgttt
    86761 tatagattta caccattaat gaatagacac ctaccgcgat aattgctccg atcattggac
    86821 ctgcgattgg tacccatgaa tatgcccaat ctgaagttcc tttattagct attggcaata
    86881 ccgcatgtgc taatcgagga ccaaagtccc gagcagggtt gattgcatat cctgttggcc
    86941 ctcctaatga aagaccgatg gctaagatca atccacctac agcgaatacg ttcgttccag
    87001 gtgcaaattc gttttgtcca aaagctagca acccaagaac taatacaaat gtaccaatta
    87061 attctgtgat cacatttgct ggataattcc gtatagcagg acctgttgca aacgttccta
    87121 aaatcgcgct ttcatctttc gttgcattcc aatgtggcaa ataagaaagc caaacaagaa
    87181 tggcccctgc aaaagctcct aaaacttgcg caatgatgaa aggaacgaca agattccaac
    87241 taattgcccc tgtcatcgcc atagctagag agactgcagg attcaaatga gctgggccca
    87301 tgaatccaga aatatagaca gccattgtta cagcgagtcc ccaaccaaat gcgatgacaa
    87361 tccagccaga agcctgtgct ttacttttgt ttaaattcac agccgcacac acaccatctc
    87421 caagcaaaac taggatcagt gtcccaataa actcccccat gatttgagtc atatcactgt
    87481 tcatttattt ctcccccttt agttcccgca gatctgattc tgcaatcaat gcttctaaac
    87541 gtttagtctg ttgcgccttc tcctcttctg tccattcaaa atatccagca attgcatcga
    87601 tcacaggttg cttgatctca tcaagctgat ctcgttcaaa caacagatga tttgtacgac
    87661 gaatgagata atcgcctggg gccaaaacca tttcttcttc taaaccataa cgtaaccgag
    87721 ctgactcagc gagactcaaa ccaggataag gtgccatttc ttttgctaat tcaaagatac
    87781 gtcgggcatt agtcccgtaa aaatcagcga tataagtagc atcttcttcc tctaaaccgg
    87841 ctgctactcc ttcttttgct aattctgtca ctgtttcttc taatttagtt ggatcgaagt
    87901 ttccacctga aatctgatat tttttagagt cgatttcttt cgtctctatt ccgtattctt
    87961 cttttaataa ttggcgtatc aatcgcaaag ctccttctgc catcttacgg taatcggtga
    88021 ttttcccacc agataaagtc agcaaaccat ctggttctct ttctaaagaa ctacctctgg
    88081 aaatcgtaga aggtgctttt tcatcacggc tgttttccaa atggttcaac acgtcttcta
    88141 cttcagcacg agaaactttg ttttccttat attcacttac tgtatcgaca actttattga
    88201 agctcttgtc tgaaatcgat ccattatctc caccattgta atcagaacca gaattaccaa
    88261 tcaacagtgg acgaagtcct gcccagcttg cttcgatatc attcaatgtg atatttgctt
    88321 ctggatagcg atgattgatc acatccaata gataatctac atcttcttgt gtgactttcg
    88381 gatccgtaaa atctccttgg taatccgtat ctgtcgtacc aaagtaagtc ttgttttctc
    88441 ttggaatagc aaaaaccatc cgcccatctt gctttcctgt atcgaagtat gtgggttgcg
    88501 gtacaggcag ttttttcgca tctacaacta aatggatccc tttagttgga cgcattttag
    88561 gagagactgg acgcgtaaaa ttcaagtttc gtactttatc tacccaagga ccactcgtat
    88621 tgatcactaa ttttgctttg atttcgatca cttcatctgt cagcaggtca cgagctttga
    88681 cgccaacgat ttgatcgcca tcatataaaa agccaaccgc tttcatttta cttactagat
    88741 aagccccatc ttcggcagcc tttttgatat tatcaatcac taaacgggca tcattgttgc
    88801 ggaaatctag atagacaccc gcgcctttta gcccttcttt tttcaaaaac ggttctcttt
    88861 ccaatacttc ttctggtgtc agcgtataat tctcatattt ggttcctgtc acatttgcca
    88921 gtttgtcata aaggtccatt gctactttga ccgagaacat attgaaggtt gttgctcctt
    88981 cgccctcata gattggcaaa agcattggat ctggttttgg gatgtgtggg gcaatacttt
    89041 gtacgactgc acgttcacca actgtgtcag ctactacttc cacatcaaat gtcttcagat
    89101 aacgaatacc gccatgaaca agtttggtcg agcgagagga agtcccttct gcaaaatcct
    89161 gcatttcgat caatcctgtt ttgattcctg atgctgctga ctggactgcc acaccggcac
    89221 cagtgattcc gccaccgatg atcaacagat ccaattcttc ttgctgcatt ttttgaatgc
    89281 tatcttgtct tgtcttgttt gaaaacatat ggatttcctc cttattcaaa tgcttgggta
    89341 gcttttactg cttttttcca accgttgtaa agtttttctc ggcgctcttc ctccatttga
    89401 acttcaaata gcttgccagc ttcataaaat tcgcggatct cgtctgtatc tttccaataa
    89461 ccgacagcta atcctgctaa aaatgctgcc cctagcgccg ttgtttccaa gttttctgct
    89521 cgttggatcg gtacattcaa gatatctgtt tggaattgca tcagatattc attgtttgct
    89581 gcaccgccat ctactttcaa tacaggaatc ttgattccag tgtcatcttg catcgtatcg
    89641 atgatatctc tcacttgata agcaatcgac tgtaaagtag ctttaatgat atcttctttt
    89701 gtcgtaccac gtgtcaagcc aaacatagcc cctcgtgctg cctgatccca ataaggagca
    89761 cctagcccaa cgaatgcagg aacaacataa acctcatctt cgcttgtaga gcgtttcgct
    89821 gcgtcttctg aatcgctagc tttttgcaac atttgaagtc catctctcag ccattgaatc
    89881 gaagaaccag ccacaaaaat acttccttct aaagcatagt aaacctttcc atttatgccg
    89941 taaccaattg tcgtcaataa attatttttg gataattgcg gtttttcacc ggtattcatg
    90001 acaataaatg aacctgtacc ataagtattc ttgaccatgc ctggttcgaa tgccatttgt
    90061 ccgaataatg cggcttgctg gtctcctgcc atccctgaaa ttggtgcttc gcttccataa
    90121 aaatgataac cttgcgtata accataaact tctgagttag aagtgacttt tggtaacatc
    90181 actcgaggaa tatttagtaa atctaaaatc tcctgatccc aatctagctg atggatattg
    90241 aacaacatcg tccgactggc attcgagtaa tcagtaacat gtgcttgtcc atcggtcagt
    90301 ttccatacta accaagaatc gatcgttcca aacatcaatt cgcctttttc agctcgttct
    90361 tgcgcgcctt ctacatgatc aagaatccag cgtatcttcg ttgctgagaa ataggcatcg
    90421 atcactaacc ctgttttttc gtggaaaaat tcttgatagc cttcattttt taagttatct
    90481 gcaattccag ctgactgtct ggattgccaa acaactgcat gatagattgg acgtcctgta
    90541 tctttttccc atattactgt tgtttcacgc tggttcgtta tgccaatccc agcaatctga
    90601 tttggtttga tccctgattc gatgaacgct ccggcaataa ctgactgtac agaattccag
    90661 atttcatttg catcatgttc cacccaactt tcttgcggga aatattgcgt gaactctttt
    90721 tgagaactgc cgatgtgtct tcctttcttg tcaaagataa ttgctcgtga gctagttgta
    90781 ccttggtcaa tcgccatgat atacgttgat tctgtcattg tgattccctc cattatatgc
    90841 aaacgctttc tttaactact cttatcatac tactgtttta aaaaaagaaa ctgtcaaaat
    90901 tttattcttt ttttcttttt ttgacagttt tttattatga agctattttt taatcaattc
    90961 ttttcttttt tcagcgtctc tattcttctt ttcaatcgaa taatgtcgta aggtgacgca
    91021 aattctgaca gataatattc acactgtttt ttgtttctct ggcaaaatgt gatcaccaaa
    91081 tcatattctt taccttcttc ataacttcca atctcaatac cgccgattcc cctcagttct
    91141 ctgatcagat attgttgaaa agcaatacga taaatcggca gactttctaa atcgattcca
    91201 atcactactg gttttgcaat ataaaaatcg atcatcaaaa gaacattggc atactggatc
    91261 atcaggtaac taagctcact atcttcagct cttttcctcg gcaattgctg caccgctgtt
    91321 tcctgtaatt tcgccagtaa ctgtgttaag gaatgcccga gcattttctg ctgctgttcc
    91381 aaaagccgat cacgctcata gacttcgatc tttccaacaa agaaaaacca ttcattgttg
    91441 atctgggaaa tttggtagcc tactgccttt tcttctttga ttttcaaacg acgaggacga
    91501 taatgccata acatcgtttc ccgaatgtaa gtatctaaaa cagcggttgg taactttttg
    91561 ctccgtgtca aatcatactg ataaaatatt tcttcgtcta ctatcgaaaa agaaacaaaa
    91621 aagctgtaaa acatcattgt ttcgtataca ttcagttctg ctgctgttcg actaagatgc
    91681 atcacgatga ttggatcgat tgcttgataa agccggtccg actgatagag taatttcttt
    91741 tctttcaaag ttgcgtacgt acttttttca ttcaatagtc tttttttcgt aatcccgagc
    91801 cagcaagcaa tctgtgcttc tgctgatgcc gtaaacgttg tttctaatac acggtccaat
    91861 cctagaatga acggtctttt ttctggtgta ttttgcaaaa aaagcggtcg ctgatcttcc
    91921 gggatatatt ggaatagttc ataataaaaa tatcgtatct gtagctcttc tccgtataat
    91981 tgaccgtttt tgatttgtaa tccaaattcc tctaagagct ggttcaattc tttgatcttt
    92041 cgaaaaacag aagactcact gatattaaac gctgtcgcta atcgaacgat ggatacttgc
    92101 tgatgttcta ataaatagac gagcatctta aacttcaagc tttcctgcaa taaaaacaat
    92161 agaatttttt ccaaacttac atcttcgtcc aacacaagca gcgcctgata ctcatttcgc
    92221 tgtacttcta cttttttttc catcattcgg ccaatcaatt caatatcttc caaatattga
    92281 tcaaacgagg cttttgacag ttggacatgc tctctcaaac cattgataga ggctgttccc
    92341 ccttgcagaa caaggtttcg caaaatcagg atctgtaact gctcttttct ttctaataat
    92401 gcttcaatct tcataggcag tattcgccac ctttgaccac accatatctg gcacacggta
    92461 ttctggctgg aaaaatagct catgttcttc taactgttca aacgtccatc cttcttctac
    92521 tgcaattgtc agttggtcaa gaaggtggaa catctctttt ttgctttgga gctgtgctcc
    92581 aagaatcttt ttttcagaat caaatagaaa tttgagttta actttgcttt gatttattgc
    92641 tgtaagcttg tagtctacgt atcctgtttc aattttttgg ggataaaaaa tgctctcttc
    92701 ttctgtcaaa cctacgcttc ctaagaaata gccaaaccac tgattgccga ctggacgata
    92761 ggttccctga tcctttgtct gtgagccact aattgtcttg ctgacatttc gtgctgtacg
    92821 gacagcgtta tttactagag aaacatacat tttttcattt gttggacgaa aagttacttg
    92881 gatcgcatcg ccaatcgcat aaacgtcttt ttgagacgtt tgcaagtagt catctaccca
    92941 gatcgttcca tcatcattca atgttaattg ttcttcccac atctgattgt cgggacgaga
    93001 atgattagcc agcaaaacaa gatcatagtt ctcctttctt ttttccgtct ctacaatagc
    93061 ggtttcattt tcggtcaaag acacaacttg ttcttctaaa aaaagtgaaa gcccttgatt
    93121 tttcatttcc tttactaacg gttctgtcat ttcaggatct agataacgaa aaagaattga
    93181 ctttcggctt tcgtaaagat ggatttgttt ttttcttgat gccaaccctt cagctatttc
    93241 gattcctgct tgtcctgcac caataattgc aattttcttt gcattcatga tcttttgctg
    93301 aagagccgtt acgttttgta tctttttaac tgggtgaata agcgttgatt ctgcagaaat
    93361 atttcgaaac ttttgatttg aaccagtcgc tagaatcaaa cgatcaaaat ccaatttttt
    93421 tcctcctgct aaaacgactt ttttttcttt caatcctatt actgtctttt ctgtgtaaac
    93481 atggattcga tagcggtcag tcagttcttc tttcgtgatc caagaaagtt gtttttcact
    93541 ggtaaccttt ccttttaata tcaaattgaa cccgctggga atccatccta acttcgattg
    93601 cttttcaatc aaatatattt cacttgttgg catcaattgg cgaagataaa tagccgcatg
    93661 aatccctgca aacgacccgc cgacaattac aatgttcatc tgcattcctc tttcttataa
    93721 ggtgttctac tgctaacttc tcaatcagaa aacacagtat tcataactcg ctttcaacct
    93781 tatgatacat agcgatgcag cagaatcaac cctctccatc ataccgtgtt ctaggtctgc
    93841 ttctcaataa tgtactagtg gacctaattg aagagtatca tttctgaaga gatgtttcaa
    93901 aaaatgtact cttataaaag aaaaaaactc gccttttacg tacctctgtc caaataggaa
    93961 acagaaaaga acgaaaagac gagttttagc gtgtgtaatg taatagttag aatagacaca
    94021 tcatttattt ttaattcttt aatgcttcaa caactgcttc gcctaattga tgagcagatt
    94081 gaggattttg ccctgtaaga agccgcccat caatttgaac cacttctgaa aaagctgctc
    94141 cagactgata gtttgctcct ttttctttca aagcatcttc tgctaagaat ggtacttcat
    94201 tcgttgtacc atttgcttcc tcttcttcat tactgaaccc agtcactgta cgtccagcta
    94261 aaatagattt tccagactca tctgtaactg gcaacaatcc tacaacaccg tgacaaacag
    94321 ctgagaccag cccttcattt cgatagattt gtgaagcgac tttcccaaga tctattgctt
    94381 ctggaaaatc ccacattgtt ccgtggccac cagcataata aaccgctgca taatcatttg
    94441 catccacatc atcaggacgt aaggtatttc ccaaggcccg atttctgaaa tcttcatctt
    94501 cataataggc ccaatcgatt tcatccatat tcaaaacact ttgcggttct aaaggtacat
    94561 atccgccttt aggactgaca aaatctgcat cgatcccatt ttttactaat acatcataaa
    94621 aatgagtcag ttcacttaac cacaaacctg taggacgctc gatcttttcg tacttttcta
    94681 catttgttaa tacgatcaat actttcattt tcccatcctc tttctataaa aattgcgtta
    94741 ttgataacgt gctttcaaga aattatataa tgggcttggc aaataaagct ctttatatgc
    94801 ttcttcaaaa ggtttcgtta caaattcatc ctcacggttt tccaataatt tctctgccca
    94861 gtcaggatcg acgatcattt gctgtccaat tgctgcaagt tctgcatatt tcaatacctg
    94921 ctctacatct tcgcgattgc ggatcccacc gacaccaact aaagggatct ttccttgaat
    94981 cgtgttatgg accacttcaa gaatcgattt atcgttgtat ttatcagaac gagctattcg
    95041 atcatacata tttaatgaaa catgcagata atctagtttt gactcacgta atcgttcaag
    95101 aagccagatc gtgtcttcaa aacggatacc tggtgtttca tattcttctg gtgagaaacg
    95161 ataccctacg atgaatggtt ttttagcata ttgttcaacc gctgagaaaa ccgttgttaa
    95221 taattcttca ataaaacgat aacgattttc caagctaccg ccccattgat cctctcgtct
    95281 attcgaatgc ggagagaaaa attgttggat caaatacgta tttgctccat gcaactcgat
    95341 tccatcaaat cctgattcaa tcgctctacg tgtggctttg ccaaatgctt ggattgtttc
    95401 aacgatttct tcttcactca ttgctcgtgg tgtttccgca tcaggacgtt ttgctgcaac
    95461 tgcacttgca gatacaggct gttctccaga taaagttgct cgacttgtca ttcgtccacc
    95521 gtggaaaatc tgaataatcg cttttgcgcc ttctccttgg attgctttcg ctagctcact
    95581 taatcgagga atcatttcat catgagcgat gctgagttca cctggccagc cttttccgat
    95641 atcttggaca tttgcagcac cagtaataac agcaccaaga cctttagaac gttgtttata
    95701 ataagtgatc tcatcttcgg tgatcactcc attgaaaaag ctgagttgtg tcgtcatagg
    95761 cgacagcatc aatcggttct tcaattgaac tcctgaaggt aaagtaattg attgatcaaa
    95821 ttgtgacatt gtcattcctc ccataattcg ctctgattaa cctatcgaga atcatctatc
    95881 attaaaccac tcgattagtt gtacatgcaa ctaatttgct taaaaaattt tatttttttt
    95941 gtaacttatc tgttgcatca ttcattgtct gggctaattc tttacttgct tcatttccca
    96001 aaactgcttt gtatgactga tgaagttctt cccagctacc atcgacttcc ttagcaaatt
    96061 ggcgtccttg ttctgtaaga taaactaatg acaagcgacc ttcgctaact gttttgacgt
    96121 atcctttata ttctaatttt tcaacaaaac gagcaatcgt tgatggggcg gaatagagca
    96181 tttgtgcaat atctttttgt ggtattccat ctttttcttt taatatcaat aaaataaaac
    96241 cataagttgg tgccagacct gtccttctaa acgcttcatc agctaattta ttcaacatgc
    96301 gatctagctt tttcacgcta aagaaaagac attcatctaa cgctttttca attggctttt
    96361 ccatttcatc ccctccattg gcgtacatat catagtatga tttttatttt ttgtcaaaaa
    96421 acacggaata atgtccgcct cctctgtcta gatttgaaaa aaagaagtag ccatcttcaa
    96481 agaatttcgg cttgttttcg acaaaactcc ttctggaaca ccgtgaatca gaggttgtga
    96541 aaaagtcgtt tagttttgag tatgaagaaa aattttgtga aaatggcttt ccacattttt
    96601 gcataaattt ggcttaatac cgaaaaactg gcttttgaac accgtttata tcagaggttg
    96661 tgaaaaagcc gtcctgcatc aagtaataag aacagccaaa caaaaatagt tcctcatatt
    96721 ttgtcgtttt ttgagctaat gccgatggtc agctgattgt acaccgttta ttgagaggtc
    96781 gtgagcctgc cgttgaactc cgagtcacaa ggagcaattt caaaaaacag cttctcatgt
    96841 tttatgacta tggtgacttg tgatcgagga gttggcagga gaatactgtt tattcgtaaa
    96901 gaaggggctg tgacaagact tttgtcacag tcccttattt ccttttatta taggatttcg
    96961 ccatttgatt ggatgacttg tctgtaccaa tcaaatgatt ttttctttaa ccgtttcttt
    97021 gtgccattcc cttcgtcatc ttgatcaaca tagatatatc cataacgttt tgacatttgt
    97081 gaagtagaag cgctgacgat atcaatgcag ccccacgacg tataaccaaa taaatctact
    97141 ccatctttga tagcttcctt catctgctca atatgctgct tcaaatagtc aatgcggtaa
    97201 tcgtcttgaa cggttccatc ttcttctact ttgtctatag ctccgagtcc gttttcagct
    97261 atgaacagtg gtttttgata cctatcatat aattgattca aagcaattct caaaccctta
    97321 ggatcaatct gccagcccca ttcacttgat ggaagatacg gatttttaat tcctccagtt
    97381 attaagtttc cttggacccc ttcccaattt tctggatgag cactgactgc actagacatg
    97441 tagtagctaa aagaaacaaa atcaacaggg taggctgcta agatttcttc atcacctact
    97501 tctattttta agttgacacc tttttcttca aacattcgtt gcgtatacgc tggataatat
    97561 cctcttgctt gaacatcact aaagaacaaa gaagttcttt gctgctcaat tgttttttga
    97621 atatcatccg gatcacaaga atacggaaca agaagctgat agctgatcat acaaccgact
    97681 tgtgaacctt tgataatttc atgacaagct tttgtagcta aagcacttgc tataaactga
    97741 tggtgtgcac cttggtattt cgcttgttcc aaatggggat ggttttcttc aattactcct
    97801 acgctaacaa aagggtgatg ttttacacag ttgatctcat tgaaagtcat ccaatatttt
    97861 actttatttt tatagcgttt gaatactgtt tcagcgaaac gaacgtaaaa ctgaataagc
    97921 tttcgattag gccatccacc atattctgta accaaatata acggcatttc ataatgggaa
    97981 agagaaacga ctggctcaat cccatatttt agacattcgt caaacacttg atcataaaaa
    98041 aataatcccg cttcattggg tgtttcttca tcaccatgag gaaaaattct tgtccatgcg
    98101 atagacatcc gatagcattt aaaacccatt tcagcaaata aacggatgtc ttctttaaag
    98161 tgatgataga aatcatttcc gtgtctttta ggataataat acttgctgtt gggatcctgc
    98221 gccgctttta cttgctgatg cgtcatcata tgccattgat ctgtccattt ttctttaggt
    98281 aaatcgctgt cgaatgtata cacatcagac acagataatc ctttttcatc tacatcccat
    98341 gcaccttcac attgattggc cgctgtcgct ccgccccata aaaatccttc tggaaatttt
    98401 ttcatatcga tccccctaaa cttgctagtt ttcttgtttg attatttttc ttatgactag
    98461 taatgatatt tttgaatcta ctactatttg taacaataac cattgtggtc ggatcatatc
    98521 cctctttgat taattcttgc aaatctactt ccatcaataa atcgccttta cgtacttttt
    98581 ttccatcaga tactgcactt tgaaagtatt tgccatttaa attcactgta tcaataccga
    98641 tatggatcag tatctctgct ccttcttcac tgactacccc aattgcatgt ttcgttggaa
    98701 aaactgttga aacttccccg tttacagaac tgtagatttt tccgtccgtt ggaatgatcg
    98761 caaacccttc tcctaaagat ccactagcaa atgttggatc gtttacttca gataaatcaa
    98821 ttatttcacc tgctgcagga gtacttaaca ctatatcctt tgaggattct tcttcgattt
    98881 catccttgta gccgaaaaga aaagttagca tacaggaact gatcatcgct aagaaataac
    98941 tagcaactag ccaaacaaat ccttcaccaa tataaatcgg gaaagacaaa atacttcttg
    99001 tagcaactgc caaagcaccg gctcctgcgg caccagctac tccaccaaat atagctccac
    99061 atatacaagc aatgtaaaat ggtcgtttat atttaagagt cacaccataa acagcaggtt
    99121 cagtgattcc aaataatgct gtgataaatg cagataaaga taaacttttt actttcttat
    99181 ttttcgtttt caaaaatacc ccaagtactg ctcctgcttg cgcagctacg gcagtcatac
    99241 atgctggacc tagcgtatca cgaccgtaga aagaaagatt gttggtcatt actggtacaa
    99301 gtccccaatg taacccaaaa atcactaaca cttgccaaaa tccgccgata acagcaccag
    99361 ataaaacagg gctaaagtta taaacagcta aatatccagc tgcaatcagc tgacttgcat
    99421 aatctgcaat tggacctaca actaataaaa taattgggac catcacgatg atacaaatga
    99481 atggtgtcaa taaatttcga atactttcgt gcaagctttt gcgaatctta ggctcaatat
    99541 aagaaagaac ccatacagct aaaattgctg gaataaccgt acttgtatac cttgctagaa
    99601 tcacgggcat ccctagaaat cgcaaggtta tgctatcact atatgcactg acaatcgtag
    99661 gataaacgag agctgctgca ataaccatag cgatgaaacg atctgtattg aacttttttg
    99721 cagcagtata tgccaaaaat ataggcaaga aatagaaaaa tgcatcagct gctgcattca
    99781 aaatgatata agttcctgat tcagtagtta ataaattcaa actcgtacat aaggcgagta
    99841 ctcctttgat caaaccactt cctgccaaga cgcctaaagt cggggcaaaa acagcggcga
    99901 tcatgtctat aaaagagttt aaaatgcctt ttttctcagt tcctctcttt ccactagatg
    99961 catcatcttc tagtttcatt tgtttggata atacgtcata cacttcattt actgcatttc
   100021 ctactacgac ttgaaacatt cctccagctt cgactacagt gatcacacct tctagttgct
   100081 ctaccttctc cttatctgcc ttcttattat cttttagggt aaagcgtaac cttgttgcac
   100141 aatggtaaac attgctgaca ttttcttcgc ctccgacaaa tcggacaata tctttcgcta
   100201 attgtgaata gtccattttt acttccccct tgttaattaa tgccgtagca atccttctta
   100261 caagataagt atagttctta gaaaacggtt tctccattca attagtaccc cttctaatag
   100321 cgaacgaaac tgtacaatag tgtgtatggt ttacttagcc gagcaaatca ctcactgctt
   100381 gaaagaaaac aagtatatcg tttctcttat agtcaaagga gacaaaaaaa acacgcttga
   100441 tcttcctttg ctgatgtata agtggtatct caagctgata ctctgtgatt tttgtttcta
   100501 cttggctttt gataagacag cacaacaaag tctcggcatt taacggaagc ataactaggt
   100561 cagaactagg agagattagt tgctgaatgg aatctatctt tttatggatt tttatttgat
   100621 tttcttcttt gtagtaatga tcaagcagtt ttgttttctt tttttcttca actatggtca
   100681 gcttttcacg caaaatctga taaatctccc aagattcaaa ctcatctaga acactaggta
   100741 gataaatcaa atcatcccac tcaaaaataa gctcttgctc agtagtcaaa attgcatcat
   100801 attccgttat tttgtttgat tgatttttga aaagatacac tggttctatc cggcattctt
   100861 tgatccacat gttcatactt tgttgaatct gtttttttag tgtattcaaa atactaattg
   100921 gctggttact aacaatcagt atctcccctt gttttcgaaa aggattcaac gcttcggcaa
   100981 gatacaaaac aaaataagcg ctttcagcta aattgggacg taattgaaaa tgtattggga
   101041 agaaacgccg aattaaataa atttctaaag gataacggga gatgatcttt tgtacaaaat
   101101 gattcatggt attatgtccg gcatccatcc tcgttttcat ttgtttgata tgggttagca
   101161 aaaattctgt ttcatggaac aataacgaaa caggaagatc taaaaaacga ataatcgttt
   101221 gctcaaatgc tcttagattc ttctctattt ctttgttttt ttcatcatta atcatcaaat
   101281 aatttaactc taatagtcga ttttcaattg cttgtttttc ttgattggaa aaagaatagg
   101341 gtagttctga tgataacttt tttgtgaggg tctctaccat cggaataaat aatgtatacc
   101401 tgtttgtttt ttctaaaagt tcttctcttc gaagaatggt caaaacgaga taccgagaaa
   101461 atcgtatgaa gtcctctcct gaaacaatat aattatatga tataagaacc tcttttaatg
   101521 tcttttggac agtcggcatg atattggaaa aaattgtact gatttgttga ggaaaccttg
   101581 cgtgttggat caccgtttct gttccaacaa gagataagaa aattcttttt gaattttctt
   101641 cagcaatgat ttttagtcct tttgtcgacg aaacttccag ttctaattta ggattgcgct
   101701 cgatccaacg caaaatcgtt tttatttgta atgatacggc tgtttttgaa agaaagaaaa
   101761 tgtctgctat cttttgcata ctgacatacc ctttttgaaa caataagtac gtcacaatag
   101821 ttgaagctcg gaaatccatg ctggaataga ttttatgttt cgtcacctct tgtatgattt
   101881 gctgtttagt ttcagattca attgattcta aaaaataacc tgaacgttta tttgactgga
   101941 taatgatttt cttctcgtag atagcaagca tatttttgat ttcagtttgg atcgttttct
   102001 tgttggtacc taaagcttca gctaattctt cgcttgttat ccaatgattc ttatttctta
   102061 atactacaag aatttggagt tgtcgtttat ttaagtccat ttgcttacac ctcctctttg
   102121 ttataaacat acaggaaaaa cctctcaaat gacaatagtc acttgcagag gtttaaaaat
   102181 catttgaaga aagatctata ttcaaggttt ttaccattag actggataat ttgtttataa
   102241 tattcaaaac tatctttttt caatctccta aagcttccgc tcccatcatt ttgtctatcc
   102301 acataaataa agccatatcg cttcctcatt tcccctgttc ctgccgatac gatatcgatt
   102361 ggtccccacc ataagtaacc aatgatttgg caaccatctt ttattgcctc agcaatttcc
   102421 tgaagatgta tttttagata ctcacaacgt tttggatcgt ggattcgatt caattcatct
   102481 ggtgcttcat ctagtccaat gccattttca actatgaata atggtaattc ataacggtct
   102541 gtcaattcat tcatgacata acgaaaccct agaggatcaa ttggccaact ccaaggttcg
   102601 ggagattttt ccttcaaaaa gggattatcg aaaccatttg ctccgccagt atctacgcgc
   102661 atttctgctt cttttttata gacagcgcta cgataataac taaatgcaat ataatctgcc
   102721 gtgttagctt gcaagcactg ttcgtctcca tctaacatta ctggtgcaca gtcttcttcc
   102781 ttccatgtcc tgtaaatata agctggataa tgccctcggc acatgacatc ggagaaaaac
   102841 catgaattgc gtttaaattg cagtgaacca aatacattct ctggatcaca gtcatatgca
   102901 taagtcgcta atgcagaaaa gctacacata atacccatct tagcatttgg atcgattttc
   102961 tttaataatt gagtagcacg ggcgttcgct agaaacatat gatgacaggc ttgataaatc
   103021 actttttttg ttagtgtagc aatgggttca agtttatctc tagcagggaa tgtaaccaat
   103081 ccagcagctg cataaggcat acgaaaagca ttattgatct cattaaaggt catccaatat
   103141 ttcactttcc cttggtagcg ttcaaagacg gtctgcgcat aaaattcaaa aaagtcgatt
   103201 aattttcgat tttgccaccc cccatactct cctaccaatg ctaagggggt ttcataatga
   103261 ctaagagtaa ttactggctc gatatcatat cgatttaatg tattgattag tctgtcataa
   103321 aatacgagac cagcctcatt tggcttctgt tcgtctcctc ttggaaatat tcgtgcccat
   103381 gagatgcttg ttcgaaaagc ttttaaacct aactccttca gtaaacgaat atcctcttca
   103441 aatcgatgat aaaaatcaat cgcttcatga gaaagataat ggagtgattc gtctaaagca
   103501 atctcccaaa tctttttttc ttcattccac tgaatactag gatgctggtt catgatcccg
   103561 ataagcgtat ctgtcacatt aggtaatttg ccgtcttcca accatgcacc ttcacattga
   103621 ttagcagcta ctgctccgcc ccataaaaaa ttttctggaa atatttcctg atccataact
   103681 atctctcctc gctatcaaca atttcttact tgaagtatag ctcgattcat caaaacaaga
   103741 tattctaact atttcggcag aagagaagaa aaaaattgaa tgctactctt catttttaat
   103801 atttatatat aacaaataca taagacgatc cccgaaagaa aacactcgtt aaccatctaa
   103861 gcaaacgatt tattttactt ccaacacaaa tgcttcataa ggtcgtaaat caactttgcc
   103921 gtctggtaac tgtttcagag gataatttga cacaataacc cttaaagctt cacgtggaat
   103981 agtgaacgtc tgcttttcac tggacatatt acaaataacg agccattgct ggtcttcata
   104041 tatgcgagaa taggcaaaga catgctcagg cgtcttttcc actaattcat agtctcccca
   104101 gacgatgatg tcatgttttc tacgcaaatc gatcaatttc ttgtacatat aaaaaacaga
   104161 atcttgatct gctaacgctt cttctgcatt gatttcttta taatttggat tgactcgaag
   104221 ccatggaatt ccagtagtaa acccagcatg ttcacgggcg ttccattgca taggcgtcct
   104281 agcattgtct cttcctttcg ccttgattga ttccaagatt tcctcttttg taaatccaga
   104341 agaaatcctt tcgttataca tattgattgt ctcaatatct tttgcttccg cgatatcatc
   104401 gattgggcaa ttcgtcatgc ctaactcttc tccttgatag atataagggg tgcctttcat
   104461 catatggagc aagatagcaa acatcttggc actttctttt cgatacacat cgtcatttcc
   104521 ccaacgagaa acaattcgcg gaagatcgtg attattccaa aataaactat tccatccttc
   104581 atcacctaaa gatgtttgcc atttggataa tacttttttc agttcagaga tactcaaggg
   104641 tttcaaatcc catttgtctt tgccttcttg ctgatctaat cctatgtgtt cgaattggaa
   104701 gaccatggat aattcatttc ttttaggatt ggaataaagt ttagcgattt cggtagttgc
   104761 tccccatgtt tcgccaacag tcatcagatt tttgtcacca aaagttgctt gattcatttc
   104821 ctgaagatac tcatgcagtt taggtccatt acttgtgatt tctttatccg gttctttgcc
   104881 aatcatatcg atcacgtcca tacgaaagcc cccaatacct ttatcgatcc agaaattcat
   104941 catttgataa atctcttggc gaacctgttt atttttccaa ttcaaatcag gttgacgctt
   105001 gctatacaag tgcagaaaat attgccccgt tttttcatcc aactgccaag cagaaccact
   105061 gaatattgag cgcaatctat taggctcttt tccattgacc ggatcacgcc aaatataata
   105121 gtcccgataa ggattttctt tatttttacg ggcctcaatg aaccacggat gttcatcaga
   105181 agtatgattc accaccagat ccatgatgat acggatattt cttttctttg cttcttcaat
   105241 cagttcttcc atttcttcca tcgtaccgaa ttctgccatg attgcttgat aattactgat
   105301 atcataccca ttgtcatcat tcggagactc gtatactgga gaaagccaaa ttgcatcaat
   105361 acctaaatac gccagataat ccaacctgga aataatcccc cgcaaatctc caataccatc
   105421 ttgatttgaa tcttgaaaac ttcttggata gatttgataa acaactgaat ggtgccacca
   105481 tttttgttcc atgattttcc tcctataaat ggatgtttct attttttgct taatcattta
   105541 ttttagtctc tctcactaaa aattgtaacg ctttcaaata gctattgcac cttgttatcg
   105601 gtaacagaat aaaacaaaaa aacagctgag gaaattccct caactgtttt ttgaaaggat
   105661 tgatttatgc agggaagaat gctgatttca caacttcttt ataaacggtg ttcactcagc
   105721 tgtcccttgg tattagctca aaaaacggca aaatataaga aactattttt tcgttttttt
   105781 ctctaatact caggccagaa cgctgatttc acaacctctt tatttcacat tcaatatcca
   105841 catgaatccc acaaatacaa agaacagacc atacatgatt ggagatactt cttttcctct
   105901 tttagctgct aacatggtaa ttggatagaa gataaaacct aatgcaatcc catctgaaat
   105961 actataagtc aaaggcatgc cgatcaagat caagaatgaa gggatcgcaa tctctaagtt
   106021 tccccattcg atttgtcgca aagattgtgc catcaatact cctaccataa tcaatgctgg
   106081 tgcagttact tgtgaagtaa caactgatag taatggagaa aagaacaagc ctaacaagaa
   106141 gaaaatccct gtagtaatag ctgtgatacc tgaacgtcct ccaacggcga taccagctga
   106201 tgattctaca aatgcaccaa caggagaagt accaaataag gaacccgcaa gcatagctgt
   106261 tgaatcagaa gctaaagctt tccctacacg aggcatcttg ttgtctttca tgaaacctgc
   106321 ttggtttgct aatccaacta aagttcctgc tgtatcaaag aaagtcacaa gcaagaatgt
   106381 cagcactacg acccacattt gaagagaatt gatgtcccct acatgtttta atgcaactaa
   106441 aaatgttggt ttcaaacttg gtgctgcggc aacaatttca gaaggcattg gaatcaaacc
   106501 tgtgaccaga cctaaaatcg ttgtagctgc catcccgatg aagatgccac ctggtacacg
   106561 ccgaacaagc aagatagcag ttacgactaa tccaaaaatc gtcaaccaag tagaaccaac
   106621 gttgagtgat cctaatccta ctaatgtaga ttcattcgaa acgatgatcc caccttcgct
   106681 cagaccaagg aaagcgataa atagaccgat accgccagaa atcgcatatt tcaaatctgc
   106741 tgggatcgca tcaatgatca tttcccgcag cttgaagatt gtgatcaaaa taaaaatcaa
   106801 agaagcaacg aatacgccgg ctaatgctgt ttcccatgga atccccattc ctaaacaaac
   106861 agaataagca aaaaaagcat tgatcccaag agcaggtgcc gttccaattg gataacgggc
   106921 taataccccc attaaaacac agccgatcgc actggctaat gcagtcgcag taaacactgc
   106981 tccttcatcc attccagaag cacctaatac agttggattt acaaataaga tataagccat
   107041 tgagataaat gttgtaaatc ctgccagtac ctcacgtttt accgtggtgt tcaatttttc
   107101 tatttcgaag taggaaagta ttttttcctt catcttccat ccccctaaat ccgaacatta
   107161 taaataaagt ccgttaaaat ttcgatttat taataaaaca acgtgtttta tcatatacta
   107221 aaacaaaaca taagtaaaca aaaaattcgg attttaagca aaatccgaac gttccatctg
   107281 attaaatccc tttatctcaa agttcatgaa cattcacttt ggattacaag aatttcttta
   107341 ttgtgttaat aaagtttctt cattctagtc tcaaaaatca atagtgtgat ttgattttac
   107401 catttcgttt ctgttcttct ttgatgaatt cttttgtatc gacaggattc agattattta
   107461 gtccgccaaa acctgtatcg accatttttc cccagccttt tgtcttcttt tttcctgatt
   107521 tgagattctt tgctcgaagc ttctcactat gttttgctcg ccgatacttc aaataacctt
   107581 ctaatcttcc cattagatcc actgtttttc ctccttttta ttcaatcaga cgactcagct
   107641 tttcctataa caaaataatt gccttcaggg tcagaaaaat tgaaagtcaa gatgccattg
   107701 ttatctgtga tttctcctgg ttcttccatg ttctcgtaga tagtttcaaa ttcatccgta
   107761 aaaaatacta aagaaggcgg tggtcctaat acctctggtg aaaacttctg cacaaatact
   107821 tttgggaata cgcctaattc taattctttt gagatgctga gtacaatact cttaaattct
   107881 tctggcaatt cgattgtttc agaaatttct gcaccaattt tttctacaaa gaatcggcaa
   107941 atcatctcta cgtcattgac ataaagcatc acacgtgttt tttgtatcat catttgaccc
   108001 ttctttctat ttgattttct ttcctgtcta taaactgatt ccattatatc acgaaagcgc
   108061 aaacaccttg tgtttgatac tattcaagaa aaataaagca atagtttcta ggattgcttt
   108121 cctccacaaa ctttttttac aaaaaaaaaa cggcaatgaa tgccgctctt cttatttcga
   108181 ttcttttata attctgcttc tgattcatct ttggttagtg tgtgtctaac actagttacg
   108241 ccaaatgttt gatcgatttt ttccttcaac gcttcgattg cctgtgcgcc acgtgccgct
   108301 tgttcagcat tgatggattc aatgaccagc accgctgctt gtgtttcttc cgtcagcatc
   108361 gttctttggg cttcacgcca gttgagacag cgacagatcg ctccttgttc atcatagtag
   108421 atgatttctt ccggaagtgc cggagcatcg gaatctgcac ctaaaggcag gaatgattcg
   108481 ccaccttggg cttttcctaa atgcagattt cctgcgatct tttcgatatc ttctccgccg
   108541 caaggtacgc caaaagacaa ggaaatacta ttatagatat ctacaagcgg attgattggg
   108601 aaaaattccc gttcttgatt tgcacgtttc agtaaagctt caatagaaga acgtgcacct
   108661 tttttagtct tgaatgtggt aaatgcctga cgccactgag caatgacttc gttttggctg
   108721 aatgtttctt ctgtaaggta atttcttgct tcttttgctg cctcattcaa taattgatga
   108781 tacgtttctt cactttcttt tgttacgtgg ttatcgatac catttacgga taagatttcg
   108841 atggttgctt caggaaatac ttcccagaaa ttggtatcca ctattacttt tttcatctgt
   108901 tcacacctct tgattagaat aattgcttga tgaatagata gtctgtttgg ggatcatctc
   108961 ccatataaaa aacatgttcg ctgtatttga taaatccttt tttacgataa aaagcgagcg
   109021 caacatcgtt gtgttcccaa acaccgagcc aaatggctgt tttttgcttt tcttttgctt
   109081 tttcaatagc tgtatctagt aaaaatgtac cgataccttg atgtttaaat ttttttcgta
   109141 catagattcg ctcgatttct aaaaaatgat cagccatttc ctcagattga ctcgttcctg
   109201 tatttagttt caggtaaccc gcaggctctt gatcgatact cactaggaaa aaatcggttt
   109261 ctttatcttt tagctcttct gtaagttttt ctagtgcata agcttgtgtc aagtaatcag
   109321 ctaaatgctc cggtgaatta tcttttccaa atgtatctgt aaatgtttcg atactaattt
   109381 gttgtagtaa gtctacatct gaaggcgtca tttttcgaat ttcgtattta ttcacggctt
   109441 cttcctttca atagatcctt ttattgcctt ttttgacaaa attccaatct tcgctaacat
   109501 tcttgcatac tttatttaaa agatattcca attgttttgc ttcttcgtca gaaagaccat
   109561 ttaatgcgac tgcattggag tagttgtttt ctcgaatgat gaaaggatag atttctgctc
   109621 cttttttagt cggatagagt ttcttgattt ttttattttc tttatcttcc aaacgttcga
   109681 tcatcccatt ggattctaat ttcttgattg ctcgggcagt cgttgtacga tctactttga
   109741 tcatttctgc tagtttttct tggatgattc caggattttc gcaaatacgt actaaataaa
   109801 gatactgtcc tcttgttaaa tcgacttctt tgaattcgat attgctaata gaatctagcg
   109861 ctcgggcaat cattccgatg tctcgaagga tttcagccat ttcatcccac ctttattttg
   109921 tttgtaagac tagttcacct ctttttgttg caaatgcaac tattttcaat aaaaaaatca
   109981 agttcttttt taataactag taaagtatat tcttttcttc ttttacgaaa aagctcaatc
   110041 acaatagatc tggtttttgt tttctaaaat aagtaactgt ttcttcgttg ttcgcttttc
   110101 tgatagcttt ggcaactctt ctatactaaa aaatcccatg ttggaagttt cattattctc
   110161 aataaacttg gcctcttcac cgtggatcgc acaagcaaaa acaagtttat aatactgaaa
   110221 aagctgtgga atatcttttt gtttattcgt atcaaaaact gctcgcaact gagtagtttc
   110281 tactgttaat cctgtttctt catagacttc tttacgcaca ttttcttcag gagacaatcc
   110341 tatttcagca aatccaccag gaagtgacca ttctttcgtc cgtttatctt cgattagtag
   110401 gaccttgcca tcttttttga tataggcacg aacatctact tttggtgttg gatgtccttc
   110461 tccaatcgtt gtgagcgctt ttatttcttc gaaagtttct tttcctattt cactgatcag
   110521 ttccaatgaa atcgtccgga tctcctcaaa acgctcttta tcaaatacat cttttccata
   110581 atatagacca gcttgagaaa gtgcgagtag tcttttgtat tgagccaact tcttgttcat
   110641 tctcttccct tcttttttag caaatgtatg actatgtaat caagtataga agactggttt
   110701 aattacggca aataaatata atgaaatctg caataaataa aagaatgtta aaaaactcga
   110761 gaacaaaaga cattcgactt ctctggggct gtgaataaat ggcgttcaaa agcttgcatc
   110821 tgcggtaata agccccacca aacgaaaaat atgacgagct attcttgtct ggctgttctt
   110881 attaattgag gcaggacagc tttttcacaa cctccccact aaacggtgtt ctcctaccaa
   110941 ctcctcggtc acaagtcaca atattcatca aacatgagaa gctgtttttt tgaaattgct
   111001 ccttgtgact cggagctgaa cgacaggctc acgacctctc ggtaaacagc gttcaaaagc
   111061 caatttttcg atattaagcc atttctttgt tacttattgt cattgatttc tttttctaat
   111121 ttatccaata gtggagtgta atccacttga gtatagtctg ttacatcaaa ttcatatagt
   111181 gttcctaact ggaatttgtc atattttcgg tcggcgatga tctttttgaa tgcttctttc
   111241 gtaatatgat tggtcccttt cgttcgatct tccaatacgt caccatagtg ataatgatcc
   111301 atgatatagc tcaaatgacg atctgattca cgatcacgtt tgtaccgacg ttgccataac
   111361 acttcaaagt ctgctgttag gcgaatcgtg atcacctgat atccgtatct atctgctaat
   111421 tcttggagtc gtgctttttg cttatcacta aaaggatact cggacacaat cactttcttt
   111481 cctgcttcca tatacaaatc aagtgctttg taatagaaag gataaacttt cgtcctttct
   111541 tgttccgccc gttcttccaa attgttaaac ccgatggatt ctgcatagta ttccttgatt
   111601 tcatcgagcg tgatggcata catatctgga aatcgttccc gtagtttatt cataagatat
   111661 gtttttcctg taccaggact accagccaga agaatgaaat actttttcat ctcatttatt
   111721 tcctaagtta attggacttt ccaagttcat aaacagtcca atcttatgct tgacaatttc
   111781 ttttactgct tcatttgctg gaatcacatt atggcgaaga gacttgttga tttctgtttc
   111841 actaaaggtt tctttagcta ctttcgtcca gttgactaaa agctccgttc caacattgaa
   111901 tttgcggatc ccgttattga tcaattcagg ataatcttct tctttcacac ctgttcctcc
   111961 atggataact agggggacat caactactgc atcgatttct ttcagcaagg gaatgtttac
   112021 ttctgttttt gatttgaatt gtccatgatt cgtaccgata gcaatagcta atgcatccac
   112081 gcctgtagct tctacaaatt tcactgcgtc ttccggtctt gtatatacct tgtcattttc
   112141 agcgacatgg attccttctt ctgtaccgcc gattgttcca agttctcctt ctacggaaac
   112201 accgtgcgca tgggcatatt ctactactgc ttttgtcttc aggatatttt ctttgaaagg
   112261 cagatgggac ccatcataca tgacagaagt atatccgctg tcgattgctt ctttgatatc
   112321 atcaaagtct cgggcgtggt ctaagtgcaa gactgcatca accatttctt cttctgcaat
   112381 agctgtcatt acattgacta acacatgcat gccgatatat ttagcggtat cgacacttgt
   112441 ttgaataatg atcggcgaac ccatttcttt tgctgcgcct agcatagcag gaagcatttc
   112501 taggttatgc gtattaaaag ctccaactgt aaaattcaac tcttctgctg tttttgttac
   112561 ttctttcaat gttgtataca tcttttattg ccaccttatc tttttatttg tttcctttga
   112621 tcgttacttg ttttgcaatt tgtcgcatct catccatttt gcccatgtag taatcgatcc
   112681 cttgatcatc accagcacga gcagcatctg cacgcttctg gttatagagg ctcatcagtt
   112741 ttttataccc atctccgatc gtctgtttat tttccaaact cttttctaaa tattggatgg
   112801 cttgatcgtt cacatacaat tcagaaaatt taagtccaac ttgttcataa agtttcgcta
   112861 atttatgctt atcttgggta gtggaaatct cttgtttcaa ttgtgtaatc tctgattgaa
   112921 tcttttcggt cgcttctggc gatagggctt tttcttcttt tgccagaact tttttcggtt
   112981 ctttttcttt tttcttaaaa aatccaaaca tcattttccc tactttcaat taaaatgctt
   113041 tcaaaactgg gcttaagatc caggcatata agagtgctgc ggctactgta tctacatcgg
   113101 ttgctgtagc attgttgaat cccatcgaat taaagatcgt tactagcaaa gcgggcaata
   113161 atgtaataaa gaaaccatga gcaataccgc caatgatcgc tcctcggcgt ccgccaactg
   113221 cgttgccaaa tatccctgct gtccctccgg caaagaaatt ggttagcata ccaggtaaaa
   113281 tcatcgctaa gccgaacatg ggcaaagtaa acatggcaat aatcgtacca atcgttgtcg
   113341 taatgaaacc taaaatgaca gcatttgggc tataaggaaa gaaaactgga caatctaagg
   113401 cagggatcgc atcaggaact aatttcatag ctatccctcg aaatgccggc acgatttcac
   113461 ctaacagtag acgtacacca gctagcaata catacacacc cactacgaat tggatggctt
   113521 gtaaaaaggc aaacatgata tagttttgat ctcctgataa ttcagaagcg aatggttcgc
   113581 ctgcaaataa aacagtgatg atatatagcg ggaccatcac gaccatgaca gacaaataag
   113641 tatcttgcag aaattcgaaa tgtgtcggca acttgatatc ttcgatcgac tttttatttt
   113701 cgcctttctc accaaaaagc ttagcaacac cggcttcaaa taagtacccg atcgtacaaa
   113761 aatgacctaa agcaatatca tttgatccag tgattttacg aatgatcggt tgcgctactg
   113821 ccggcatagc aatggcgaaa caagctccga taaaaccacc gaccaagatc aatacgatcc
   113881 ctcgcagacc ggcaaaatag ccaaagactg tcgtcatcgt tgccatccat aaaattgctt
   113941 gaccagttaa aaaaatgtac ttccattttg tgaaacgagc caaaataata ttgaatacaa
   114001 aaatggctaa gaacgtcagt gcaatatctc tacctaaacc caaatcattc attgcttgac
   114061 cattgataga ttcaatagaa gggatgatcc cttgcatatg aaatccttca gtaaagattt
   114121 tcccgaaata agttaaactt ccaacgatga tgctcgaacc agcactcaac acttgaaatc
   114181 ctaggagtgt ctttaacgtg ccagagatga cttgtcctgc tgatttcttc tgcagtagta
   114241 gacccaacat agcaatcaat gcaatggtga tcgatgcctg agtcaaaata ttttcgatga
   114301 taaaattgat aacgcccatg tttttaccct cttttctttt tgtatttaga taactccctt
   114361 atcttgcaga actggggtga ttttttcttc aatttcattt tttgaaacaa tatttttcaa
   114421 atagatcatc gccgttttag gatcaactgc gaacttttcg aactgcgaac gaaaattttc
   114481 tgctgtgatg atcacatctg gtttcatgga aactgcggaa gaaatatcac aatggtccag
   114541 tttggcttct actcctaatt tgttcaaaac atcctcagca gacatctgtg ctgcaaaact
   114601 acttcctaaa cctgcaccgc atacgaataa aatgttcaat ttgttcatct ttgttctccc
   114661 ccgtatcatt tattatttct caactactga aaaaagcagt tgtttgaaat cttcgatatt
   114721 tgtgcattca atcaatcgat ccaacttctc ttcgttgttg atcaattcaa ttagttcttt
   114781 catgatgttc agatgcgagt aggagtctac tgctgccaaa caaaaaataa tctttactgg
   114841 atccatttca ggattaccga aatcgattgg ttgctcaatc gtagctacgc tgactcctaa
   114901 tttattgacc ccatcttctg gtcgggcatg ggctagtgcc atgtgtttgc caatcacgat
   114961 atacggtccg taatcattca ctgcacgaat catcgcttcg acatagcgct cttcgacaat
   115021 gttttcttta accaatggtc tagcagctag ttcaatcgat tcctcccaag tagtggcttt
   115081 ttctttgatc atgatattgc tgtccgtcaa aatatctttt aacataggct ggatctccct
   115141 tttgttgatt tctaaattgt ttgtttcgaa taatttttct aacttgccat agatgattcg
   115201 atctactcgg ccaccacttt ctttcatgac atctattatt tgagtgaata actccgtcga
   115261 ttcatgactg ttaggctcta accgctgtag ttcttcattt cttttcaaaa agtcttctat
   115321 aaccaagata ttcgtctcag ttaaaatcgg atcgacaact aaaagcggct tatttcgata
   115381 attcaattga aaggtgctga aaaccagatt gacatccaat ttatctacta attcgatttc
   115441 ttttgaactt aaaactgcag taatctcgat ctgaggaaac ttttctttca gattctctgc
   115501 taacagattt ccagtagcca tcccatggtt acagacaacg actgatttat aaacataatt
   115561 caagtctcgc ttgattacac tggcgatcgt cgaaaagtgg atgacaagaa aagctatctc
   115621 gtcctccagt atcttgccac caattacttc ttcgatcgta ggaacaaaat gagtgactgc
   115681 gcggtagatt gggaaataat ttgttcggat gttttctttc aatggattca tgacttggat
   115741 atgattcttg attcttacaa tcagtgcagc catgtgctta tagagatttt cgaataaagc
   115801 ttcttccttt agatggaaag gtacgtgtgt ctcgttctct acaaattgga tcaattggat
   115861 cgttagtaat tgagcttgta cccactcgat tgaattggag atatctctag cattgaacgt
   115921 ctcaatagtg aaacgaagat aatttctttc tacttgcggg acattgtcca attgaaattc
   115981 ctcgatcatg tggtcaataa atgcagaaaa gctactgtct tttatttctg tatttttcca
   116041 attaatggca gagataaatt catgtttcct gattcgctgg atccagatca atgtaaaaag
   116101 caggatttgt tttttataaa tatcatcttc ttgtttcaac aacttattgg aatagatctc
   116161 ctgtattttt ttgatttcca ccaaaggaaa ataatggaga aagatttttt gagccggtgt
   116221 taattgtgca tcttgattca taaagaagtc ggtcattccc agattctgat tgataaaatc
   116281 atagatcatc gtacggatag atcgttctga acctttataa accagtcctt gctttccata
   116341 actgacgatc tctatcccat aactgaccag tgttgctcgt aaccgtctca tatcttcatc
   116401 taatgtactt ttagagattt gaaattcttc ttcttttttg tttagatgga tcgggattcg
   116461 gctgtaagca acggctaaaa ctagatcaaa aatacgttcg cgccgattca aaaagccgtc
   116521 tttcacatct tttatttcag tttctaatcg agcttgcttt tccttttcca gcttcaacaa
   116581 aaaacctttg ttgcgaattg tacggatctc cggaagcttt ttactgctca accagatatt
   116641 cgcttcaaga acttcctgac ggatcgtccg ctgactgaca ttgaactcac ttgctagatg
   116701 ttttgctttt actggatatt gggctgtcat gattctgtga agtatttcaa ttgttcttgt
   116761 tttcatagaa atgatctcct tctgatttca agtatatggt tccgcttaca taataaaaag
   116821 tagatatttc tgccacttga agtggaaaga aagtaagcaa agcaaacaaa aaataagcca
   116881 tatgcttttt catctcctca acgaaaaaga catacgccta ttattacaaa aattttgccc
   116941 atctatacaa aaaagaggtt gtgaaaaagc tgtcctgcat caagtaataa gaacaactaa
   117001 actaaaatag tgcttcctat ttttcgtttg gttgttctta ttatcgcaga tgcaagcttt
   117061 taaacaccat ttagtggaga ggttgtgaca gagatgttca gccttgagcg ataagaagcg
   117121 attttgaaaa atcgcttccc atattttaca aaatcgtgcc ttattgccga taggctatct
   117181 ctggcacacc gtttattcag aaaaaggagc tgcgacaagg cttttgtcac aactccgttc
   117241 ataaatattt cctgtcaatc cagcataatc ggctgaataa aatcggcttg ccatcttttt
   117301 tctttctcag aaaaatcaaa ataccatatc tgagaaaaat actgtcgttg tgtcttactt
   117361 cctgagatca atcgcccatc ttttcgatcg actgaataat cacagcatct gaaatcaatt
   117421 cggatggcaa aactattttc gtggatctgt cgataatttc ctacttcctg aatagttatt
   117481 tttttagtat gatttcttac accgtctgct ttgttttttt gcagaacttt ctgatgttcg
   117541 gcaaacagct tgtctgtata acagcttctg gctttttcag gagtttcttc ttcccaagcg
   117601 gattggatct tcatgaatat cttttggatt tccagaaact gtgctttctt ttctttagcc
   117661 gttcctgaca tgcgggacaa tatctccgct ttcagccttt tcttttgtct tttattcttg
   117721 acgatagaaa aagcagaaac ccctcctact gacaaaacag ctaatgcaag aaatcccgtt
   117781 tgctcataac tagaaggacc tgtacctgga ccataatacc cataagaatc tctgccgtaa
   117841 gaacgactgc caaaataact gcccccatat gaacgaccac caaatgaacc tctgcccgaa
   117901 cttcgaccgc tagatgtacc tccaccatga ccacccgcga cagcgaatcc ttgggtcggc
   117961 agagcaaaca aacataggcc cactaacaaa atgattgcta aataattgat ttttttcatt
   118021 gtcttcctcg ttatctttta ttacaaaaaa ctatttttat gatagccttg ctaaaaggaa
   118081 gagtcaataa ccagatgcat aaactgtttt tttagcaatt ttgtcttatt tagtcattga
   118141 gtaacatcgg acaaatgtat gtgtcggcag tccataattc ctctatcttc agcatgaaca
   118201 agcttgcaga caagagatct gcgcttcctc caggagagat ttggttttcc tgacaaaagt
   118261 gcaacagtgc tgtaaatgga cgatttggta aagcactttg actagcagca tgagcaagtt
   118321 tttgcatttc cactaacgtt ttctgatcac tgcgatgcaa tacgcatgtg tcatctagcg
   118381 aactcatcaa aactaacaac atatgcattt gtttctgtac atatgaatca ttatctagct
   118441 ccttagctgc ttgaattgca agcctgatat gcggataccc taatatcgct tcttcatatg
   118501 caccatttac gccatatttt tgcttcaccc tatgaccatg agtggttttt ttatgacgat
   118561 attttgtatc aggaaaagca gcaagcttgc tgacatcatc aagtattttc gataaagaaa
   118621 aaggctgttc catactgatt ttttgtgcaa tgacactgat caatagcccc attgcccaaa
   118681 tcgctccttt atgggtattg atgccatttg tagcaatcag cattgccttt tccgcttttc
   118741 gcccaatctc agcaattctt tctcttaact cctgatcaat agcatgatgc catgctattt
   118801 gagccatttc ttcaaaaaaa ggagttagcg tcttagcaga cttaagaaat aaagcatagt
   118861 ccatatcgga atgtgcaccc gcatccagtg catccactaa tccaggtttt ggacttaatg
   118921 ttacttctgc gatcaatgct tcctctacca acgcagcgag ttgctgagtc actgcttttt
   118981 ttcgttcgtc atttatcatg acactcactc cttcttccta ctattacttg ctgaaacctt
   119041 ttttgatagc tacccaaatg atatgaagta accagcttaa agcaaatgca caacttgccg
   119101 tcattagata agctacaaga atcatgactc ctgaaggtaa ctgcagccaa ctatctttaa
   119161 acaataataa cagtacttgg aaaacaaata cattggctaa atacgtacga taagcataaa
   119221 cagacaacca tttgaacaat ggcaattttg gcgaatcgtt tacaatcatt ttggaagcgc
   119281 ctatgaagac agcaaagatg atgactaaac tgtataaact ttggatcgta ttcaagtaag
   119341 gtgcattcgc aaagctcaag tctcctggat gtgcgagcaa tgaacggaca gaaaagaacg
   119401 cgataactaa ggcaacaggt aagaaaagat aacgtactct gtccaaatat tgatagactt
   119461 tttcgtgata aacaaatgcg gctaccccat aaatcatgaa actagcaaca aaccgatcta
   119521 ataagtacca gctgtcatga taaggcccag tcaatacttg tgtttgatag aacagatacc
   119581 atgcgacata taaaatcgtt gaaccaatca atactggcca tacatatttt ttattagcaa
   119641 atactttgta accgagccaa acaaaaaacg gcatgaacaa ttggatctgc agcatcataa
   119701 cggtatacca taaatgaggc gctccatcac ctgtgacata tttcagtaaa aagcttgcag
   119761 tatccgtata cggagtttgt tgttggactg ctggaaatag ccaaagataa gccgtcgtcc
   119821 atagaagata cggaacgact agttcaaaaa acttttcttt caaaaattcc caataagaca
   119881 aatgctgact tgtttttacc atattataaa caattgcaaa aataaacatt ggtgctgtgt
   119941 atttaacgat gacgtaaaag gtaccaagaa aagctgtatt tgttgcgctg tggctgtttg
   120001 ccaaagcaaa gctcaatatc gtttgcatca taacagccgt tacagctgat actttctgga
   120061 agtcacttac gttgattttg atttttttgt tttcaaacat ctctttctct ctctttttct
   120121 ttattaccaa agttctttgg ttaatttagg tccttcgact gttttcaata gaattttttt
   120181 ctctggctct ctcaaatact cttttagtga aaaaccgcct tgccgagtca ctacttgggt
   120241 atcgaattgc tcaaaaaaag caggatgcga ttgaattacc tgaattggca attcaatcgg
   120301 tgaatttgcg tacagcagca aatcaaaatc actggtttct tttactgccg gaatcccagt
   120361 cgataattca aatcctaagc tgccgccgat tccccattta catcctgata atatgtttct
   120421 agcagcatga aattgctgat aaacaggata atccatgatt ttctcttgtc tatacgattc
   120481 ttgttcgatg atgtcccacg gatgaatgac ttgtttgacg gcatgttttg agatttctgt
   120541 tgaccatctc tgattgcggg caggtccacg taaaccaatc ggtagtattt ctgcgtgatc
   120601 cgtcgacgca cgacgaactg ttccgaacat cttttcagtt agaacgaccc attcaggcaa
   120661 ggtgaaccct tctatttcat gtttatcaaa aaggacaata tcatgtgctt gaatcatttt
   120721 ttatgcatcc cattcttcgt ccattttggc acggacttta tttgtttcga cacgtccgaa
   120781 tgttttggct gtttcgtttg tgtatcgatt tgtcagcatc gtgtcatttg tattgcggac
   120841 atcttgaatg gcttcattga ttgcttcgat gactttgctg acattttgtt ctgaagcagc
   120901 ttggtcggtg atatcttcta ggaaatgata gatcgctcct agttttgtat aattattgat
   120961 atcgtaagcg atagctggaa ctttttcagc agctgcttcg atttcagcaa ccgaacgttt
   121021 tgtcacacgt gcagcacttt ctttagacat cgcttggacg gtaatttctt tattgtttaa
   121081 agcaatcaag cggcttgatt gtaatccatg tgctaaaaat gcacctgaaa tagcatttcc
   121141 tgcaatcaat ccaataactg gatgtccagc ttgacggagt tttgcataag cagcagcact
   121201 attagccaaa gccacatgga taccgatcaa ttcttcgtta tagccgtatg cttggcttgg
   121261 tacatcgatc acaacgatga ttggccgttt cacttttttg tctttatctt cttcgtaaac
   121321 gtgatccaaa atttgtccca tgcggaaacc ttcaactaaa ccaacttcac cgtttcgtac
   121381 acggtacatc gggtttttag gatcaggtac gattgatgtc acgatggctt cttctatgaa
   121441 tttacttgat ttaccataat acacagtact aatagaagaa gttggatttt tcatgccagt
   121501 tagtgccgca aaccaatcgt aaccaacact tgctgcagct ggttcatttc cttctgctac
   121561 ttctggtaag tcaattgatt ttgcttgatg gttagcaatt gcttcattgt aatcgtcaat
   121621 ggccattggt tttgaaagat ctaaagaatc aagtaatgat aaataaaatg ctgagctttc
   121681 actgcgatgc gtgtcttttc gttcgtccat tgctgcgatg acagcagctt tgattgcttc
   121741 tacactatca gtcactaatt catcaatgat ttttgattct acccgttgac gagatcctaa
   121801 tgtattccaa atcaagtctt tgtcactaga atcaaattct cgaacgcctg cttcttgttc
   121861 aataacttct ggtccattca aaccgactct cgcttttttt gttgcgatta aataactcat
   121921 taatgctgaa gtaatcgaca taccgccaaa tgatcctaca cgtcctggaa tcaaaccgat
   121981 gactggtaca tattgtttta gagcaatgat tacatttccg atttctgaaa tagataacag
   122041 tccgtagttt gcttcttgca aacgaacacc acctgtatct agtacaatga ctggaaagat
   122101 ctcatttcct tttttatttt cttctaacac atgttcaagt gcagcaacga tttttgcacc
   122161 ggaaacttca ccgataccgc caccttggaa ttttccttcc atagcgatta ctactgcttg
   122221 tttgccattg atcgtgccac ggctgacaac gatcccgtca tcactttcag ggacgattcc
   122281 ttgtgctggt aaacttggcg cgatgatttg atcgaatgga tcaatcaatt cacgtccatt
   122341 gtcaagtaga gcgttcactc gttctctggc gtttaattct acaaaactat ttttcatctg
   122401 aaagttcctc cattgcttgc gtcaatcgta ggtacacaac tcctggtgta gcaccgaagt
   122461 cattgatcac gatatctgct gaaattggat aacgatcaaa aaatctcgtt aatacattgt
   122521 tccatacttc gccgaagcca tcgcttcctg tacaaatttt tacagtagat tctgtttttt
   122581 ctgttggaaa catcaagatt tccaaatctc ctgaaccgac cactcctaca tggattttct
   122641 tattgatcgg ctgtttcgtt ggatatttat aagctaattg ttccatggat ctctcccctt
   122701 tttgtaaaac agagcataca cgttctgctt attcgtcttt cttcttccat ctgggtaaat
   122761 ggcgacaaaa ggtttttctc gccaatttta tgaccaagtt ctgaatttca ttggtggttc
   122821 atacaggcca tctgaccatt cgatcaaatc atcgatggtt tgtgcagcta ataatgaacg
   122881 tttcgcttca ctacgtttga tgcctagatc ttctggtaat ttcacgatgc cggctgcacg
   122941 caagctatct agtgattctt tcgtgctagt cattccaaga ggtgtaacac cgccaattgc
   123001 tgcaattgct gcttgtcgtt cttcttttgt ttttgctttg tacaaataag caattccttc
   123061 ttctgtcacg atatgtgtag tatcttcgct ataaatcatc actggtgcat tggctaagcc
   123121 tgcttgtttt tgaacagcta gtgcatctaa ttcttcgaca aagactggtt ttttatttga
   123181 accatatgtt tcaaccattt gaacaactaa tttttggcct ttccctaatg gatcatcatt
   123241 gtcgcgaagt gattgccatg ctggtgtaga atgacgacga ccgccaggat tatgtcccat
   123301 gttaggcgca ccgccaaaac cagataaacg tccttttgtt acggtagaag agtttccttc
   123361 gtaatctaat tgcaaggttg aaccgataaa catatcgatg gcatattgtc ctgcagcttg
   123421 tgataatgtt cggttactgc gcatcgtgcc gtctttaccg acaaaaaaga catctgggcg
   123481 agcagcaata tatttttcca taccaacttc gccaccaaaa ctatggatgc tttcaaccca
   123541 acctgattcg atggctggaa tcatcgttgg atgtgggttc aatacccagt tcttcgcgat
   123601 tttccctttt aaccctagtg attcaccata agttggcagt aacaattcga tagctgctgt
   123661 attgaatcca ataccgtgat tcaaagattg tacgccgtgt tctgcgtaga ttcctttgat
   123721 tgccatcatt gccattagaa tttgcaattc tgtgatgttt tgaggatctc gtgtgaataa
   123781 agcttctaat tgataaggtt tatctgcttt cacgacaacg tctacccagt caccagggat
   123841 atctacacgt ggtaaagaat cgacaacttc gttaacttga acgatcacga taccatcttt
   123901 gaaagctgca gcttcgatga ttgttggtgt ttcttccgta ttgaaacctg tgtacaagtt
   123961 gccgtcttta tctgctttat ctgcagctac taaaacaaca tttggaatca aatcgatgaa
   124021 taagcgtcca taaagttcca aataagtatg gatatcacct aatttcattg tgccgtcttc
   124081 aatcatttgg gcgacacgca agctttgtgc accagcataa gagaaatcga tcttgcttgc
   124141 gattcctttt tcaaaaatat tcaaatgttc tggtcgtgag atactagaca tgatcaaatg
   124201 cagatcattc actttttctg catctacttt ttcaagactt tctgaaagaa aacttgcttg
   124261 tttttgattg tcgccttcta atacaacttt gtcgccggga gcaatcagtt tttccattac
   124321 ttctacgatt ttttcagttt ctacatactt gccattgagc aagttgctga ttttttccaa
   124381 tcgctgcgct tttttttcgc gtttagaagc ccagttgcgg tttggttttt ccataattag
   124441 tcatctccat ttttgatata gaaacgtggc gtcatcaata ccatgttggt ctagattgat
   124501 cgtacggatc cctttatcta caccaaattt tgtatgaatc agctttgtca aagtattgcc
   124561 ggggggaaat tcaatcgtca gatccattcc taattctttt gccaagtcca tcatttggtt
   124621 ccactgcaca gggaaagcta ggttttccaa caaatcttta cgaatctctt ctgcgtcctg
   124681 agtggctctt ccatccgtat tttttatata caaacatcta gcatcagata gatggacaga
   124741 ctgcatatac ggcttgaatt tcttgaccgt atcattcatc aagagacagt gagatggcac
   124801 agggactttc agcagcttcg ctgtttgcgc ttggtgccgt ttggcttctg ccaacgtaac
   124861 ggataaacct tcgatactcc cagataacgt atgttgcatc ggacaatttt catttgacag
   124921 ataaactgga tggtcaggat caaatgtttt tgctacaatt tcctcagctt cgcttctcgt
   124981 cacacctact actacgccca ttgcataacc gcttggataa gcttctttca ttaagactgc
   125041 gcggtgatag actagttccg ctgcattctc aaatctcaaa gatcgacaag caacagctgc
   125101 acaaaaagca ccaatcgaat gtcctgctgc aatatcaggc tgaataccgt ttttttccat
   125161 ttcatctaaa taaaatactg cttttgtcag taatgctagc tggataaaaa ccgtatcttg
   125221 atagttttct tctttatcaa ctaaccgata ccccgtcaca ttttctaaac gttccatgta
   125281 catttcaggg atatccgcta acatccctaa cttctgactg ccttgtccag gaaataagaa
   125341 acctgtactc atgagcctcg cctcctcagc acttactttt tccactgcta tcttagtcaa
   125401 tttctgctat aataaaaaat gccaaaaaaa gaaaaaacca taacaaaaag gtatggatgg
   125461 gatggataat tatgaaattg cttcatctgc agtattttaa aaaagtattc gaaacaaaaa
   125521 atgttaccca agcagccaaa gaattattta tttctcaacc tgccttgagc cgtgcgatca
   125581 aacatttgga aaacgaatta ggtgtccctt tgttttacca tagcggcaga aacattgaga
   125641 cgaccgttta tgcagaagaa ttttatccat atgcagtcaa gacattagac acattagaag
   125701 aaggaatcaa attattgtct tcggtcaatg agaagatcgt tacttccgtc atattgtatt
   125761 tagaggtagc ctctgtttct attccgaact tggtccgaat ttttatggaa aagcatcctg
   125821 atatccaatt aacgatcatg caacatcatt taccagatga tattaccgat cctgtactgt
   125881 acatcacttc ggagatgaag cctggcatga ccaatattcc tatcatgaaa gaacctgttt
   125941 atgtcgccat tcctaagaaa catcctcttg ctaaaaaaga acatctgcaa ttagaagata
   126001 tccaacgcac ccccatcttg atgctgtcaa agagcaacgc cttccgtcat acactggatg
   126061 cagcacttga agcgaaaagt atcgaattga cgatcagttc gacgacagat gatcctgcga
   126121 cattacgttc tattgtcaag caaggattag ctgttagctt tttcccaaaa gtttcttggt
   126181 cttacgataa aaatgatcct ttcgtcttgc gggaaatcaa agatttgccc ttgacacgaa
   126241 caatttattt atcttctagc ttcacagaag atcatccttt gatcaaaatg attgcaaaaa
   126301 cgatgcggga attttattta ggaaaataaa aaaaaaagag ctgggacaaa attcttgtcg
   126361 cagctctttt ttcgaacaaa cggtgttcca gaagtaattt cttagaaaat aagccgaaat
   126421 ttcccaaaaa tttgagaagc aattttcgta aattccttct tatttcttga agctaaacat
   126481 ttctgtcaca acctcttctc tattgtccta gacattcatt gcgttgattt aaaacttcca
   126541 tcaatcaaat ctgctagttc atctagcttt tctattttac gtagatcaat agagatccaa
   126601 tgttctttat tcatgtgata ggctggaaaa tacccctctt ttcctcgcaa aattccgcca
   126661 agttcaggat cgaccttcaa atcaagaata ttgatgatcc tatggtcact tgcatcatca
   126721 tagatttttt cttctggaac agacatcagg accccaaacc attttttgct tttttgatgt
   126781 ctgaatacgc aataatcagg aaatttttta aaaatatatt ctggagacaa attgtatgtt
   126841 tcattgatgt gatcgattag ttcttttttc gttagcatct gcttccatct ctttcttatt
   126901 gattcgcttt attcaaagat accacgtaag aatagaaaaa tgaatacaag tagttgctaa
   126961 tcaaatactt cgatattttt cttttttatc aactcttaaa tgttcaatcc gcctgtgttg
   127021 gtcttgctac catctactat taaaatgttt attattgttt gcccacctat tttttgattt
   127081 tagtggtatc atttttcaag ttcatgatga aattcttatc atcagtaaat gctccagaaa
   127141 aataaacaat gattgaaaaa tcagttgaaa cttgaccacc gtttattttc tccgtattct
   127201 tagaatagaa gggagtctga ttgatgtatt cactaatgaa aaaaatcatt accgaaaaag
   127261 atattcgacg tcatgtttct ttagtagaac aattgctgaa tcatacaaag ataaccgtaa
   127321 atgaattagc tgaaatcata gggacaaccg aacgaacgat tttttctgac cttcaatcta
   127381 ttcgctctca gctgcccgaa ggctgggaca tcatcagcga tcaagcagga atcagtttgc
   127441 aaaaccagca aaatttatta acaaatgacc tttgggagat ttttttcaaa caatcagtca
   127501 gtgtcgaact gctgaaaaat ctgcttttta caaaaaaagt tgctgtccct gattttctag
   127561 ccgaccatgg gctttcttat gggacattga aaagacatgt gactaaaatc aatcagcgtt
   127621 tagcaagtta cgacttgcag atcgatttga cgaaatatac agcttgtatt cttggaaaag
   127681 agcgtgcgat tcgtactttt tatcatcgat tgctgattcc tttcactcat aacaactatt
   127741 ttttcgagga ttattcgatc catgaatccc attattttca atttttaaga aacctcagtc
   127801 aaactgaact agcggttgaa acagaagaga ttttcggaac atgttggttc tttatcaata
   127861 cgatccgtat aaaagcgaat tgccgattag attcttctat ccataccaac agcacactct
   127921 cctccctgta tgactctgca ttgaaaaaat tgtatttaac ggaaggtatt tatcttaaag
   127981 acactgagct ttcttttgct tctttctgct ttctggaaag ttggaattac aacaataact
   128041 atggacaaga aaccgctcgc tgcctgcatc attctccatt tttagaggtc ctcgaaacgt
   128101 ttgtagagga actagcttca gagctgtctc ttgatcaact aaaaaaaaca tctctgactg
   128161 ataacttggc tctcctcata ttaaaatatc atgaatcgcc gatattgatt gaagcattgg
   128221 accgtcaata ccatcgtttt ttagaaacat atgatcagca atatgcacac ttgtatcaac
   128281 agaaagagaa tttactgaac gatctaaaaa aagaaataga aatcaatgaa ccaaattact
   128341 ttctccaact cttgtctcta ctgatccaac aaacgatttt ttctatcaaa ccgaatttgt
   128401 tcaatgtcta ttttattttc caaggagaac cttcatggaa ggcgttcttg cagcaggaat
   128461 taaaagatta cttaggaaaa cgtgtctgct tcttacctat cgaactaacc gatctttcca
   128521 ctatttcttt tgaaaaaaca gatatcttga tttccaattt ccctctagat tctctagata
   128581 tccctattgt atacatttct tctattccaa cgaaaaatga gctcaatcgt ttgactgaac
   128641 tcactttcaa aactttttta tagtaacggc tagcgactgt attctctagc tgttttttct
   128701 tttttgcgaa acagtttgtt catgatccct ttttctattt ctacaactaa gaatagaaga
   128761 atcacatttg ctccaatcaa taactgttgt gtcatcgtta aacttactgt accgatcagc
   128821 tgctggccga ctggtagaaa aataaccatc ccttgcaata aagcaaggat acctaatgaa
   128881 agaaaaagcg ctttgttttg caaaagacct tggttcaatg acggcttgga caactctctg
   128941 caattgatca tgtaaacagc ttgagctaag acgatatttt gcagaagaat ggtttgctgt
   129001 aagctttgcc cttcaaactg catagccaat aaataggcag gaaccatgat cagtagggag
   129061 acatagatga tccgaaacaa atgataacca gataggattc cttgctttgg atctcttggt
   129121 gggcgcttca tgatttctgg atctggcgac tcgaacccta gtgcataaga taaagtgatt
   129181 gtcgttacca tattgaccca taaaatctgt actggggaca aaggtagcgg gcgattcagc
   129241 ataagtgccc aaatcaagat caatccttga gctaatgcag ttggcaagaa gaaattgatg
   129301 gttttttgca aattatccaa aatccgccgg ccctctttta cggcttttgc aatcgtatgg
   129361 aaattatcat ctcctaaaac catatcagct gcctgtttgc ttacttcact acctttgatt
   129421 cccatagcaa ttcctacatc ggatcttttc aaagcaggtg catcatttac gccgtctccg
   129481 gtcattccga cgatttctcc atttttctgc aaagctttaa caattcgcag tttatgttct
   129541 ggtgtcgttc gagcaaagac atcgactatt ggcacttgct gaatcaactc ttcatcagac
   129601 ataagatcca aatcgatccc ttctaaaact ttggcagtat gttttaagcc aatttgttcc
   129661 gcaatcgctt ttgctgtgtc tttgtgatcc cctgtaatca ttttcactga gatccctgct
   129721 tgttggcatt cctttacagc tttgactgca ctttcttttg gcggatcgat caatccggcg
   129781 atccctgcaa aagttaattg ggttaaagtc tcatgcgtga gttcctgttt cgaatctact
   129841 tttttataag caaatcctaa aacacgctga ccttttctcg caaattctgc agctgtctga
   129901 ctccatgctt cttgttctgc agaagaaaga gttgatttag caaataatac ttctggtgca
   129961 cctttgacgt aaatcaccgc tcctttttcc tccgcatgca tcgttgccat atatttgtat
   130021 tcagaactga acggaatctt tgcttctatt tttttcaaag gtagattggc tgtttctgtg
   130081 tgtcgaatca gcgcaacttc tgtcggattg ccacttaaat tttctgtttt ctgttcttct
   130141 tttgttttta attcctgaca gtttttcata atggacaaca cgcaggcttc ttcttttgca
   130201 gctacatcca caactgtcat ttcatttttt gtcaatgttc ctgtcttatc tgaacagatc
   130261 actgtcatag aacctaatgt ttctaccgaa ggaagtcctt tgatgatcgc cttttctttt
   130321 gccatttcat gtactccaac ggatagaatc atggtcaaaa cagctggcaa tccttcgggt
   130381 accattgaca ccaccaaagc aatcgtagcc gaaagaagaa tatgccaatc cataccatat
   130441 cgaaatgtcg taaaaataac taagaatagg ctcaaacaaa gaatgccttg aaaaatttgt
   130501 ttgtttaatc ggttgatttt tttaatcaga ggcgtcgttt gttgttcgac cgattgcaat
   130561 gcttgattga ttttaccgat ttctgtcgtg tttcctgttt ctacaacgac accgactgca
   130621 gaaccagatt gtacaagcgt tcctgaaaaa cccatatttt tctggtcgcc gatcgattct
   130681 tcttctgtca aaacggcatg acttttttca gatgcttctg attctcccgt caaaatcgat
   130741 tcttccacta ataaatcatg tgcttcgatt aatcggatat ctgctggaac gacatctccg
   130801 gcacgtaaga caatgacatc tccttttacc agttctttcg cagggatttt ttcttgcatc
   130861 ccgtttgata gtactatcgc ttcttgtccc atcagctgct tcaaaccatt caatgattct
   130921 tccgcttttc tttcttgcca gtaactaacg agtccattga cgatcactac gaataaaata
   130981 atacttcctt caatatattc actagaagca aatttcaaaa aagaggcaat gatcaacacg
   131041 atcatcagca gatcagtaaa atgctttgct atttttttcc atcgttttgt ctgctgcctt
   131101 gcttttattt cattatatcc ttgatcagtc aggcgtttct gtcgttcttc ttgcgacaag
   131161 ccttctgttg atgtttgata gtttttcaat acatcttcta ccgtcaatct gtaccagttc
   131221 atcctatccc ctcctgttta attgatactg ttattatacg cagggaagtt ttttcaggcg
   131281 tatcgattat ttcagggggg tctgaaataa ttcgttttgc aaaatgtatc tgggcctaac
   131341 tgatatttct attgcttatt cttttatata caaaatttaa gaatacaaac cagataacca
   131401 ataaaaaagg aataaagcgt gtcgtgcttt cgaataacaa gctgaaagca attgaagtaa
   131461 aaaacaccaa caaagcaaga tctttatatc tttgtgtagt gttccgtttc ttttctttaa
   131521 taaattgaac atgtgcacac aagatcgaag accacacaaa tagaaaacaa ctcgttgtca
   131581 tgcctgccaa aagctgaaaa aacaatcgac tatcagctac aaaaaaatgt agacaaagac
   131641 cggcaaaaaa taacattcct gtaattaaaa taccgtgtaa aggtacgcct ttcttagaaa
   131701 gcgcacaaaa ccaatggggc aaactttttt cttttgctgt ttgatataaa atcctgctag
   131761 tactgtagac tgcactattt gctgaggaca aagaagcaac caaaatcatt agattgacaa
   131821 ttgctgctcc gccttggcaa tggatcactt gcagcatagt cactaaagga ctttctttta
   131881 aatctaaaca atgccatgga acaacaaata aaatcgacaa aatcgttcct atatagaaaa
   131941 agagaatacg ccaaggcaga cagttgattg cttttttcaa attcttttgc ggatcacttg
   132001 tctcgccaac ggttaagccg atcatttcaa ttccagcaaa actgaataaa accataggaa
   132061 atgagactac cattccagca aagccaaacg gtagtaattc atcgatctgt ccaaaatttt
   132121 ctttgattcc gatagactgg gtatgaaaat ctgagacact caatcctata cccaataaga
   132181 taaaaaggaa aatccccaag atcttgatga ttgagaaaaa agattccaat tcaccaaacc
   132241 acttgactgc aacaaggttg actgccatta agatcattag tgcgctacct ccgcttatca
   132301 aagctggtac atgtacaaac cagaaatgga tatacaatcc tattgctgtt aattccgcaa
   132361 gtccagctcc aagccagcaa agccaataag tccaattgac aaaaaatgcc cactttttgc
   132421 ctaaataata gtcaacgaaa tcactgatag agttaaatgt actatttgct aaaaataaat
   132481 cacccatggc ccgcatcaaa ccataaatag ccaaaccgca tatcaaataa acgagaataa
   132541 cagctggccc tgctgatgca attgcctttg ctgaacctaa aaataatcct gttccaattg
   132601 cgccacctaa tgcgattaac tggatatttc gattagttag agtccgtttc attgccggtt
   132661 tttccatcaa gttcaccttt ttctttttca agcagcatgg cgacttcctg ttcccaagaa
   132721 ggtttcttta ttttttcaat acagagtggt actacaaaca aaatgacact gatggctgtg
   132781 actgcaatta gattgatcca tgttccagct ttcatcgtca gtccgacaga aaatccgatt
   132841 gccgcaaata aaacaataac gacagtccaa actccaagat tgctcttttt ctcttttttt
   132901 ccaattctaa atggtcgatt caactttgca tgtgtataac gcaatctcaa aactgcgatc
   132961 cccatgatga catagacgat acagtagata acagtagttg aatttacgag catcaaaaat
   133021 gcttgattga cgccaggaat cagcaaataa aaaagtgcaa agattgagat aatgacagac
   133081 tgagtcaaaa taacggattt ggatacgtca aattgattcg tcttccaaaa attgaatttt
   133141 ggtggatacg caccttttct agcactttct gtcactgtct ttgctggtcc tgaggcccaa
   133201 gcagataatt ggactgctac accaatgaag acaagtaaac taaacagatt cacaataaga
   133261 tgtggcaaac caagaatttg gcaataaatc gaaatagatt gcgcgatatt attcaattcc
   133321 atttgtcctt ttggtacgac atttgctaca actaaagcat tcaaaatatt gacgaaaaat
   133381 ataaaaatta acgcggcaaa tactccgcga atatacgttt taactggatt ttccaatcga
   133441 gtgatataca cagaggacat ttcgatacca gtaaaaataa acatgatcgg cgcaaaataa
   133501 acaaatgagg atgcagtcgt agtatctggt attaatttgt cccatgaaaa actgcctaat
   133561 gttccggttg gtacgatccc aactttgatc cacgcagcaa accctaataa gagcatcatc
   133621 gtcaaaggca cgtacaatcc taaccaaaca ccgacttttc cgccgatttt tgccatatca
   133681 aatttcaaat tcaaaaaagt gatgatccaa taaacgacta aaatgacaac taatgtaaat
   133741 ttgctgttca aaccaagcgg cacattatcg ataatattac caaacaacgg agcgagtgct
   133801 gaagcgacca tcaccatccc aggaaacatt tggacccata acagccatga gacaacgaac
   133861 ccccattttt ttcctagagc attcgatacc caaagttctg gaccaccttt ttggggaaac
   133921 attccagcaa attcaccaga gatcaatgag attggaaaag cgtacaataa tactgcaacc
   133981 agcatgtaaa aaatcatcgt ccagctcgtt gctgctacat ctggaatatt tcgtacactt
   134041 gctacaaggg cgcaggtcat tccgataaag gtcatggtcg tgatttgctt tgatgaacca
   134101 gtatctttca tctttattcc ttctttcaat agcgacatat gtttttgttt tcttttattt
   134161 ttgttcaaga acagaaatga caaggtttca tcgattcagt acaaaaccca gtatcaccga
   134221 aacatccatt gaacgatctt agtgaactgg gtttgataca tgaaacgaac gatccaactt
   134281 atagaacgtt ttataaaaaa gaatatcttg gcgaggaata tatgaaaaac agggggaaat
   134341 acaattgttt tgatgaagca aataattgtc tgttctccat atgtctcttg ttattctttc
   134401 acacaaaaat cagttctatt ggatgatttc gtttagtttc ttttccattg ctttggcgat
   134461 tttttttgta taaaaattga aaattcgatc atcattcaaa taaggagtca tgatagccgc
   134521 acgtagcaga gtgattttct gttctttttt ccattcttct ttcgttagac ccattctttc
   134581 aacaaaacga atcggagaat caccgtaatc ttcttgtgta aatgtagtat gagaagtaat
   134641 aaaccgttca ccataaacat cgccatccat ataagaagac cgatcgaaca ttttttcatt
   134701 taattcattg atagcgttca aatctgtaca gccttgttct ttgaataccc aattgaccat
   134761 attaaaatca ggatgattca atggatagac ttcgattgtt tttcctttaa cagtaaaagt
   134821 cagatgatcg agaaattctc tgaatctttg agctgcctcg attgaagccc caatcaattg
   134881 accatatccg gtcacattca atggcaatac acgatgtgct gtccagactg cggcggcggt
   134941 tgctccagct tttgatcctt ccaaaatata agctcctaac atatctggag cctttactga
   135001 tttttcaaac acatatggcg cgaaataaga aatgatattt ctcatatttt tatgtttgat
   135061 tacgattcct ccagcagcat aagggacata gcccatctta tgaggatcta tcgtgacaga
   135121 atccgcttct gaaatagctc tgaacccttc atatacctct ttgtcaatcg ttacgcagtg
   135181 gtggaaaaca tgatgttctt caaagaattc agctaaggaa gcatacggca caaattctcc
   135241 tgcttcgttt agaaacagtg aacgcgcata gccgccatat gcggcatcaa catgtaaata
   135301 gaaatagatc ccttcatctt ttaacctttc tcttaattgg acgattttat ctacactgtc
   135361 tacttgacct tcttctgtcg ttcctacgac agcaaccaca cctagaattg ggattttttg
   135421 tccagctaat tcacgaattg ttttttccaa agcattaata tccattcgat aatcctcttg
   135481 aactgggata gcaaccatct gatctaagcc gactccgcaa atatctaacg ccttcatcca
   135541 agaatagtgt tttgtttgag ggaccagcca tttccctaat ctttggatat tttttccgct
   135601 acgggaagaa gctgctttga cctcatccat ttcttcgtcc gtaaagcttt cggtcatttc
   135661 caaaatttct tcaacagata aattcaaaag ttcccactca gacatttttt tcactttttc
   135721 aggcagcact tccttgacag ctaaaggaat cgatttgatg caacgggcgt accataatcc
   135781 ttcaagatta gcaatagaac catctgctgc aatgtgtccc catccgtctg tcatattgaa
   135841 taatgaagca aaatcctgtc ctacttctgc ttccatttgc gaagttgcca tagaagattc
   135901 caatgcaaca ttatttgggt tccacagcat cgcatagttg taagctaata aagcaggcat
   135961 caatgtttca gcattcattt gtccccagta acggcctgct gaatgccatg ggatcgatcc
   136021 tgcgcgtaat cgctgactga cttcatccaa gacctctatc atatggtcgc gggtggctag
   136081 ataatctgga gtgagcttat ctccttcgct aattgcaggc atatctgaag gaatataatt
   136141 ttctctccat ccaagatgtt catctaccat cttgttcaac aacattttat aaactggtcc
   136201 attttcagct ttgtcgccta taaagacggc cttgatatcc atatctttca tttttcttcc
   136261 ctccatattt tgttggtcaa tgtcttgcag atacatgtgt ttatctgtaa cacctcttca
   136321 ctatagcgcc aaaaatgaga attttttttt tataacatca aatccacgta gatttttaca
   136381 aacaaaaata aataaagtcg gatttttctg ataattcaac gcaaaaaagc gaacaatttt
   136441 tcaataaatc agtcttctaa aatagataac ctaaaaaaag cgaacaaaca aataaaatga
   136501 ctgtccttca ttcactaaac atatttttat ttttttatat tgttaaaaat tcgcaattta
   136561 ttttttaata gaattatctg ttttccaaat tttataacat aaaaaacctt ttttaacggc
   136621 atttatatgc tttttcagaa attaactgat gatttcaaaa agaaaacatg tcataatatt
   136681 tcccatattg tgcaaaaaaa tacaaggcgg aggctctact atgattgaag aatatattga
   136741 gaaaaatatt ttaagacagc tgtttttatg tgggcaattc tatgtaaata aagaagtcaa
   136801 tctagaaaag ctctccaatc tcctgcatgt ttgcaaaacc actttactca atgatatcaa
   136861 taacataaaa aaagaatttg aagaacagat cgcttataca catcgggaaa aggaccgtta
   136921 cactttatat ttttcagaac atatacctcg atgcaagatc atgcagcaat tgtctcaaaa
   136981 ttcgttgttt ttaaaaactt gtctgcttta tttggaagaa gatgaacctg attatcttca
   137041 attaactgaa tgtgaattca tctctgtcag caaagcttat tcattaaaaa aacaagtatt
   137101 agcttatttt aatgactgcg ggatcgaaat cgaccgctac tcccctcgat tcactgaaat
   137161 ggaaagacgt ctgctgcttc ttaatgtgtc gtatcgttta ggcggtttta attcttggga
   137221 gctacctgaa tcgttttttg aacgtgccga tcgtttcatt gaatccgtaa cggaaaatag
   137281 tggcagattt tatgataaag aaaataaaga aatcttatcg attggttttg ctatcagttt
   137341 cctacgccag caagtgtgtg ctgtgacaat agattcaaaa tttatcgaag aaatcaaaaa
   137401 acgtcctatt tacaattatg tcgaatcagc atgggaaaac actgatttcc aaacctatta
   137461 taaaaaagaa gaattcgcct ttattttgac actattcaat ctttgtaatt atggtttcca
   137521 ttcttatcag ttgattgcgg aagactttca acagctacac caagtgttta ttgacaatac
   137581 tcccgaaata aaagaactag ttgctacctt tgaatctcac ttcaatcaag aattattcgg
   137641 aaaccaaccg ttcgaacgtg cgctgattca tctgatgcgt tcggcttggg ataactatca
   137701 attattcatg ccagaaaaat tttatctttt aaatgaggaa cagacaaatt tatataaaga
   137761 agtccagaca attttttcca gctggtccag ccagttacct tatgatctac ggttgaatcc
   137821 taattgcatg cgggcttttg tgatcgaatt gagcggaatt ctccgtctga caaaagaaca
   137881 tctgactatc tatatcgtca caaattcgga tgttcattat ctgatttatc gggaagcctt
   137941 ggaagctgta actactttcg attttcaagt tgcaccaaca atttattcaa gtatatctga
   138001 tataaagaag tatgcgcagc agtcctcaaa ccgggtatta tgtgaacgta cattatatac
   138061 accagatgcg gtccaatatg aaaatattat tcctatttcg atcaatacga tcgatcgagc
   138121 tatcatttca gctgtgcaaa acaaataagg ggctgtgaca aaaatcatgt cacagcctct
   138181 tatttgttga agatgcccat ttctgtaaca atctcttgat acacgtcagg ctcacaacct
   138241 cacttatttt ggacatctac gggtccgatc tctttattta aaaaataaga aatgatggtt
   138301 cggataacta ccaacgccgc tagttggaaa atatcctgca aggtaggttt gataatcgat
   138361 tcgatgatcc cagctgaaac aagaatttcc aaacttagaa gtatatagcc tcccaacatc
   138421 tttttaatag cattgttctc gctgactcgg tcgctttgca cttttgtatg gacaaataaa
   138481 tatttcaaaa aatccttgat tgatagacaa acaccccaaa ccaataaaca gatagcaaag
   138541 atatcaagtc ccagtacaag tttttcgaaa tatggaagaa gaaactgcat caactctgtc
   138601 gtcatcctac ctctcctctt ctttgttttt ctttgtcttc tatttcctga ttcaagaaat
   138661 aagaaatgac tgttcgaatg ataataataa gtgcaagctt caaaatatct gtccaagtcg
   138721 gcttgataac tgactcgatg atatcagcaa cgactagtac ttccaagctt aacaaaatat
   138781 aacttgctag cagttttctt gtatctgcat tacgagtatt acgttctgca tagtttttct
   138841 tgacatgaga ccaatcaaaa agtttgaata gaacaagaac gatcccgaca attaagatac
   138901 cgatagaaca aatatttaaa atagcaatga tccattctag aaattcaatt aaatttgagc
   138961 gaaacatata cgctacctac tttcttttaa tttgttccta ttcttttatt gtaaaagaaa
   139021 gttaccttgt tcgtctattt aaaagttgtt ctaatgataa cggttcgctt aaatttttct
   139081 ttttcactct cccatttttc tccctccatc cataaatcgt ggaagtatcc aaaacaacgt
   139141 agcaagttaa aataaggctt agtccgtcat cagcttttca aagaagcact gtctcggtgc
   139201 tttttttgta cccaaatttc taaaaataga accatacacc tcctcaaatc ttttcttctt
   139261 acctacccta tttttattta caggaaaatc agacacttct tcttttttgt caaaatttcc
   139321 tttttcttct cgtcctatca tttggcattc taataaaaac gaactatcct tggatataga
   139381 aagagaaaac aaggaggcgt ttttcatgag taaaaaatta atcaaagtcg gcatcggttt
   139441 aggtttgctt gcccttggcg ctgcatatct aggaaaaaag acaggactat tcgaagatga
   139501 cagtcattta tatgatgaat tcgaatcaat ctagcatcct atttagttga atcactacgg
   139561 acatacttgg aagacattgg aggaatcaca atgagaaaaa gtaaagcaat aatgattggt
   139621 gccggtattg ccaatatggc agcggctgtt tatttgattc aagaaggcaa atggaaaggg
   139681 gatcagatca ccttttattc attggatgat cacggttcaa atgatggtgc accgaccgac
   139741 actgtagtgg atgaatattg gaataaaaac catccattag aaaaccaaaa aggctatatt
   139801 gctcgaggcg gtcgcatgct taattaccgt acctatgtag atttgatgga tctgttaagt
   139861 cgaatacctt ctgttactga gccagggatg actgctgaag aagatacgag agattttgat
   139921 gcaaaacacc gaacctttga caaagcacgt ttgatggaag gtggcaaagg aatcattgat
   139981 ggcggaaaac tgggattcaa taataaagac cgtattcttc tgactaaact gattgctatg
   140041 cctgattcag aagaagaaaa actagacaat atcactatcg aagaatattt caaagatgat
   140101 ccacactttt ttgaaacaaa cttctggttt atgtgggaaa caacatttgc tttcagaaca
   140161 cgtagttctg ctcaagaatt gcgtcgctat atgcatcaaa tgatttatga attcactcaa
   140221 atcgaacatc tagtgggcgt caatcgaaca cgttacaatc aatacgaaag tattatgctt
   140281 cctttgatcg agtacttgaa agaacaagga tgcaaaatca ttttgaaccg ccgtgtcact
   140341 gactgggaat tcaaagaaac accgatgcaa gatgaaatca ctgtgactgg tttgaaaatt
   140401 accaatacac tgactcaaga agaagaatac gttgtggtcg atgaagatac agcagttatt
   140461 ttcactaatg ggtccattac agattcagct actttaggag attacgaaac accagctgta
   140521 gaaaatatgg attatggtgc agcttctagt ctctggaaaa aagccagtga acgtttctac
   140581 aacttgggaa atcctgacaa attctttgct gatcgagatg caagcgaatg ggtcagcttt
   140641 accctgacga cgaaaaacca tttgttgttg aatgaaatca cccgtatcac gactcaagaa
   140701 ccaggaaatg ccttgaattc atttatttca accacaccga tcacgccgtt aggccaaaaa
   140761 gatgtcaata tgtctatcgt cgtgcatcat caaccgcatt ttacgtctca gaaaccaaat
   140821 gaaacagtta tttggggtta tttcctttat ccaagacgac gtggcgaatt tgtggataaa
   140881 cagtatatta aaatgaatgg aaaagaaatg ctagaagaac tgattggaca actttcaaaa
   140941 gtagatcctg gaccagtgaa tattcgtgaa aaagaaacag aaattttcga cagcgtaata
   141001 aataatatcc ctgtctatat gccttatgct tccgcgttgt tcaataatcg tgccaaaagc
   141061 gatcgaccaa aagtcattcc taaacattcg accaatctgg cctttacagg agaatttgtc
   141121 gagcagcctt atcagatgat ctttactgaa caaagtgctg tacgttctgg agaaatcgct
   141181 gctttccatt ttgcgggtat tcctatgtcc cgtcttgtca aaacaccgcg ttacgacaaa
   141241 gatattccta ctctagctcg tgccgcaaaa aaaatgtttg aataatcaag aggttgtgaa
   141301 aaagctgccc tgcatcaagt aataagaaca accaggctaa aacagcttct tatgtttttg
   141361 atttggttgg acttattacc gcagatgcaa gcttttgaac accgtttacc aagaggttgt
   141421 gaaaaagctg ccctgcatca agtaataaga acacccaagc taaaactgct tcttatgttt
   141481 ttgacttggt tggacttatt accgcagatg caagcttttg aacaccattt accaagaggt
   141541 tatgaaaaag ctgccctgca tcaagtaata agagcagcca agctaaaaca gcttcttatg
   141601 tttttgactt ggttagactt attaccgcag atgcaagctt ttgaacaccg tttaccaaga
   141661 ggttatgaaa aaggcgttta gtttcgagta tgaagaaaaa ttttgtgaaa atggttcctc
   141721 acgtttttgc ataaatttga cttaataccg agaaactgat cccttctgtc ataacctctt
   141781 tttatttatg tctgtttctt tttgaaaaca actatttttt caacgtttac tctcttgcca
   141841 atccaacatc atctaacgga tacaactatt tcaatgatta ccattacact aaaaaatcgg
   141901 aaacacacct ctccgaacac aaatacataa gactatagaa tgtttcattt aagaaaaaaa
   141961 gcgtttcatt atcaaaaagg taagatctcc tttaaaatga aattatctgt agtactaata
   142021 atgcagacaa ttttatgaat ctgaaaggag catctccaat gaaagcagtc acttggcaag
   142081 gaaaacagaa aatggaaatc agaaacgtag atgatccaaa aatattagaa ccaacagatg
   142141 caatcatccg tatcacagca acagccattt gcggctccga tctgcatctt taccatcatg
   142201 gtgaagcagt tttggaaaaa gggtatgttg taggacacga accaatggga atcgttgaag
   142261 aagtgggatc tcaagttcaa acattgaaaa aagggcaacg tgtggttatc ccttttaata
   142321 ttagttgtgg tcattgtcat ttctgcctga atcacatgga aagccaatgt gatgaatcaa
   142381 atccagatca gttatatggc gggcttttcg gatttggcaa gttgaacggt aatcattggg
   142441 gtggtcaagc ggaatatcta agagttcctt atgcagactc tacttcattt gttgtaccag
   142501 ataatgatct tcctgatgaa aaagttttat ttctatcaga tattttgccc acagcttatt
   142561 ggagcgttga aaacgcagga gtaaaaaaag gcgatacagt tgtgattcta ggttctggtc
   142621 cagtcggtct attcgctcaa aaattcgctg ttatggctgg agcagagcgc gtaatcgcag
   142681 tagatccagt acagcaccgt ctagataaag cggctaatta caatggggtt gaaacttatt
   142741 tcttagaaga cacggcacaa gctggaacag aattgtatga actggctaaa ggtggcgcag
   142801 atgtcattat cgattgtgta ggaatggacg gattagagcc tgtcaaagaa aaagcgaaaa
   142861 atttagtaag cttacaaagc ggcacaatct ctccattaca gatggcatcg caagctgtca
   142921 aaaaatttgg aacagtccaa gtaactggtg tttatatgac tccagcttct tcttacccgc
   142981 tgcaagaatt ttttatgcgg gatatcgctg tcaagcatgg acaggcacca attatccatc
   143041 taatgccaaa aatttacgca atgattgcag aaggactatt cgatcctaca caaatcatta
   143101 ctcattcgct gccactatca gaagcagcac aagcatatga gatctttgac aaaaaagaag
   143161 ataaaaatat aaaagttgtt ttgaaacctt gaattcagta aaaaatacag gtgattttct
   143221 ttatgcccaa aatcaaacga aatacccatg agatcgaaat aggaaaagaa gaagatatcg
   143281 aaatacgagg acgtcgcttc cgcttctatt tccaaaatcg ttacacattg atctcactgg
   143341 ctgtcgattt attaaccggg attttctata tttttggaag ccttgcttcc ttaactaaaa
   143401 tccccgatcg atatggcacc tatttttatt tggctggtgc tattttcttg acgattcgtc
   143461 ctattctcag aatcgtaagg aacattttta tttacgacga aaaaaaagca atgaagagaa
   143521 caagcaaaaa aaaagaggca tgagaatttt tcaaatctca tgcctctttt ttcaccctat
   143581 cgtatcactt tgatacagac gagcggtcgt cccactttct tccttgacca ttgtcaaaaa
   143641 tgtccactcg tatcgttcat aaaacgtggt atgatctgta attaagtaaa gtttttcgta
   143701 cccaagttga tgcatttctt ttctgatttc cgctaatatc cgcttggcta tcccctgctt
   143761 acgcttttcc ggttcaacaa acagggcaca aagatttggt gtcagatcag ggcggttatg
   143821 gaagtcgttt tcaatgacgc ccgctcctcc gacgatggtt tctttttcat ctaagaccac
   143881 ataccattga ggaatacttt ccttattagc gattccagta cgaatacttt cctcatacac
   143941 aacagcagga actccccatt ttgatgaaaa ccaattcgcg ctttgtttta ctaattctgg
   144001 gtgttctctt aatttgatcc agttatatgt aaccaatgtt taaacctccg actaaaataa
   144061 aacgtttaca aaaattatac aagtctttat gaaaattagc aatgacaaca atagtgatgt
   144121 aaaaaaaaaa cggaaaacaa tcacttgttc tccgtttttt gattaatcaa gcatctaaag
   144181 cttcttttct tctttcttgg atcgtagcta ccttgacgaa cggtagatag atcaaaatag
   144241 aaagaaccaa attgacagcg gctagtacac cacctgcaat actttttgtt gccaatacac
   144301 cgccaataat tggtggagtt acccatggag gcataacggt agctgctggc actaaacctg
   144361 tagaagtcgc aaagtaagca acactaacta agaccattgg tgtcaaaata aatggaatga
   144421 acatgatcgg gttcaacacg ataggtaacc caaacatcgt tggttcatta atattgaaga
   144481 cacctggcgc aatcgacaag tttgttacaa ccatatatgg tttgttttta cgtcctacta
   144541 aataaatagc taacagtaaa cctaaagttg cacctgttcc tcctaagttg acaaagctgt
   144601 caaagaaagg tttgttcacg ataaacggtg cgctatgccc agctgcgatt gcattaacgt
   144661 ttgcttcaat ggctggcgca ttgattgttt gcatcaaagg atcgaccata ttcgctccgt
   144721 gtaaaccaaa gaaccataag aatggtgtga taaatgcaag cagtaaggca gatggataag
   144781 agtttgcaag tcccataaat ggttcttgga ccactgtata gaaagaacct acgatatcat
   144841 caacaccgaa tgcagcaaaa attgcagcaa ctaaagcaaa cgcagagata gtgatcattg
   144901 ctggtagtaa tgaagcaaat gcttttgcaa ctgccggtgg cacaccatca ggcattttga
   144961 tgatcaattt ttcatttccg cttaaacgta caaagatttc tgttgaaata atcccaacaa
   145021 taatagcaat aaacaaaccg tttgagctca tacctaatgc tccgcctaaa gcgaagaaag
   145081 agcctaaaga aatcacacct gcggaaacac cgtcttttcg gtagccgcta gctaaatgat
   145141 aagcaagcaa gaaagcaatc aagacagaaa gaatggcaaa tgtaccgttc caagcagcag
   145201 ccccgaatcc tttccatgat tcaccaccaa aaattgagtt catcaattct tggaacccgg
   145261 gaatcggtaa gttattgatc attactgcta atgctcctaa gatcattaac ggcatactca
   145321 ccataaatga gtcccgaatc gcaactaaat gccgttgtgc accaattttt gatgctacag
   145381 gtataaaatg tttctccata aatgcaacaa atttatccat aaatcttccc tcttttcttt
   145441 actgtagatt acgcgttcaa tcgacgatac agatcaatga tctcttttgc taaatctgta
   145501 aaagctatag atgtcatcag atgatcttga ctgtggaccg tcaaaagcgt gacttcaacg
   145561 tgatttcctt gtgcttcttg tgtcagcatc tctgtttgag agtgatgtgc ttggactaaa
   145621 gattcctctg catctttgat tttttcatct gctaaagtga aatcaccttt tttcgcagca
   145681 gcaatcgctt ccattgcatc gctttttgca tttccgccaa acatgatcag acccatgatg
   145741 gcttctagat ttttttgatc ttccatttat tgtatcctcc gataattttt attatttgtt
   145801 tattagtttt tctgcttggt cgagtacttt ttcaccattc atcatgccat agtcagccat
   145861 attgattaca tctaaaggaa tgcctttagg tgctagcttt tcagcaaatt gattttgcat
   145921 aaagcgtact tgcggtccta aaagtaaaac gtctacattt ttagattcta gttgattatc
   145981 cgcatctgaa gcagatacag caaagatgtc tgcttccatt ccttttgctt ctgctgcctt
   146041 ttgcattttt gtgactagga gacttgtact cattccagct gaacatacaa gcatgattgt
   146101 tttcttttcc attttaaaca cgttcctttc tatacttaca cttgtatata agcaagtagc
   146161 gtgccaactt taaaagcgct ttaaaaagtt gatatcatca catttaaggt ctataccaag
   146221 ttgcatacac actaaaaaag aaagcgcaca ctaaacacac aaattaattt ttattacctt
   146281 ttttctttta acgtgcacaa aaaaagttgt gacacaaaac ttgtcacaac ttttttcaaa
   146341 taaacggtat tcaaaagctt gcatctgcgg taataagtcc aaccaagtta aaaacataag
   146401 atgttgtttt tactttgcta ttcttattac ttgatgcagg acagcttttt cacaacctct
   146461 caataaacgg tgttcaatca gctgaccctg ggtattagct caaaacgctg gattcacaac
   146521 ctcttttatt tcaaataacc agtaaataca atgaacatct acaaaaaact tctatttatt
   146581 tatagatttc gtcaggcaaa tccaattctc tcttatcaat caaagtctga taccacgaag
   146641 cagatttttt caatgttctg cttcgttcat cgttcaattc gattcgaact aatccatatc
   146701 gattcttaaa tgcattcatt ggtgacacac agtcagtgaa tgcccataac atatagcctt
   146761 cgcaatttgc gccttcttct gttgctttga tcaagtaatg caaatgctgt ccgataaatt
   146821 cgatacggta atcatcttgc acgattcctt tctcatccat atactgttct tcatattctc
   146881 ttcccatacc gttttctgtt atcagccaag ggatattatg ataattttct tttagataca
   146941 tggctatatc atacatgatt ttcggataga tttcccatcc cctggaatta ttcattttct
   147001 tcccaggtaa atcaaagact tcataatatc gttcaggatg gaaaggtgtc tcttcattcc
   147061 attgataacg aggggcgcga acgcgtttag gataatattg attgattcca aggaaatcta
   147121 ctgtatgatg ctgaatcgtt tctaaatcct ctgttgcagg atcgaaataa atcgattgtt
   147181 tttgacacaa ctccaggaac tcttctgtgt agtatccttt taccatcgga tcaaaaaata
   147241 ctcgattata aaacaaatca tacatataag cagctttttg gtcttctgga gaattggatc
   147301 gagcatagac catttcagga tttaaaatac agccaatcct tccaccataa tttccgctgc
   147361 ggtaaatctc tactgcttta gccgttgcta aaactttatg ataattccac atcatccact
   147421 tttttgtgtt ttgttcatgc ggccagcgaa cagcatccaa atagcaacgc gtttggggaa
   147481 cgattggttc gttgaatgta aaccagtttt ttaccctatc accgtaacga tcaaaggcaa
   147541 tttgagcata cttagcataa aaatcaacta cttttcttga agaccagcca tcatattttt
   147601 ccaaaagaaa agctgggact tcataatgtt ccaaacaaat catcggttct acgtctgctt
   147661 cgatcaaaga gtcgatcatt tcacttatat gctgagcata ttcttcatct actatacagt
   147721 tctcataatc agtaaaaaaa cgagcccaat tgatagaagt ccgataatgt gtcagatgga
   147781 tggatttcat cagatccaca tcctgctggt attgttccat aaaattagtt gctacggctg
   147841 ggccataccc attatgccaa acaaaatgtt catttttata ccagctatct ataaacgaat
   147901 cctgtccttc tttttttcct ttccaacctt ccgtttgcca agcagaagat gcagcaccaa
   147961 gaataaaatt ttttggaata gtaattttca tgatttcctc ctgtttttta gatcccatca
   148021 ttttccacac gatttgctac ttttacaaat ggcagataga tcaaaataga aacaataata
   148081 caaacaagtt gcgtaataac tgcaccgata tttcctgctg ttgccagata agcattgacg
   148141 atcggcggca ttggccaagg gaccattaca actgctttcg ccgcaaatcc taaagcggtt
   148201 gcaaaataac caatcgttcc agtgataaga ggcgttaaga taaacggaat agctaaaatt
   148261 ggattcagca tgatcggcat accaaaaata actggttcat tgatgttgaa gatcccagga
   148321 gcaagggata acttggtgat ttgtttcata tcttcccgtt ttccaactaa caatactgca
   148381 atcagtaaac cgatcgtgac tccagacccg cccatactca tatacatatc ccaaaatggc
   148441 atagtaataa tgttcggtac ttcttttcca gcttcaaaag cttccgtatt tacagcaatt
   148501 gccgctaaaa gcaacggttc ccgtatcggc ttcaccattt gatttccatg gataccaatc
   148561 acccaaaaga cttgcgcaat aaacatcaat agcaaaatac ccggtaaccc ttgtacgaca
   148621 ccttctaatg ggcgttgtac gacattgtaa atgatatcat aaaggtacat tcctgtaagt
   148681 tctttgatga taaatcccgc agccgcgata cccgatacag tcagaatcgt cgggaataaa
   148741 gcagaaaaac tagcagaaac attcgttggc acggtatcag gcattctcag ctgtagtttc
   148801 ttctgtttcc tcaaccagca ataaagttca atagaaagga tggagaccaa cattcccaaa
   148861 aataaccctt tcgtatctgt atattgttta gccaatacgt tttctactat aacagtctga
   148921 ttttcattca ctaattcata aacagttgga ttaacagata aataagacat cactgcgatg
   148981 ataccaggga atacaccatc cactttattc agcttggcta attcgatccc tatcagaaaa
   149041 acagcataga tggtcaagaa acttagtgtg acatagctga tggcagatgc gataggcttt
   149101 aattcttcta aaaaacgcaa gaaacttatc tgtgctaagc cattttccga gtcaaagacc
   149161 attgctgaaa acaatgtgcc aaaagcaccc gtaataatta ccggaatcaa tgcagcaaat
   149221 gcgtttttta tcaccatgat ataccttaaa ttattgattc tcgttgccac gttccctaaa
   149281 acattggcta atttatccat aaaactcatt ccagatcccc tcattcctgc ttcttctcct
   149341 tgacgtcatc tctttttgtc tattagtcag cgcttacatt tcgatgaaca gaaactattt
   149401 actcctcttt tttaccaaat ataaaacaaa aattcatctg atgtatttat cataaaatac
   149461 atcagatgaa ctgtcaatta gtttcttttt ctcctattat tttctgtaat tctctccgat
   149521 ttattgccat atggacagtc attgcatcaa acgcagcaag tgcattccgc ctttcgatgg
   149581 cctgaacgat ctctgtatga atatcgatcg tctcgatttt cagatgctgg atatcataat
   149641 ttttattaaa caaagcaatt gattcattaa tgattgggat aatatgcagc aaggctacgt
   149701 ttccgctagc ttctgcaatc atcgtatgaa aatcgatgtc taattgaaca tgttcttgtg
   149761 tgccttctcg aaaagaagtt tcaatctttt gcgttaattt tttcatttgg acgatttgat
   149821 tcttcgttgc atattccgct gccaaacctg ccatcttagg ctccaataaa tatctcagtt
   149881 caaataagtc tcgtatcatc cgatcctgat cttcaatcaa agaaaaaccg agtgggtcat
   149941 tggcaatccc tcgcttatca ctgacaaatg tccccgctcc ttgccgaact tcaaggatat
   150001 tcctggaagc tagagcccgc acagcttctc gcaccgtgct tcgccccacc tctaaataat
   150061 cggacaattc atattcattc ggcagtttat ctcctacttg caactgcatt tcctttaaat
   150121 atctaaggat cttgtcagta gttacttcta ctagggtttt attttcttcc aaaccacata
   150181 cctccttttc atctgatgta ttttttcgta attattataa cacgtttgaa tcatctgatg
   150241 attttttgta tacaaaattg attaatccgt tcatagacat acaaacgaag aagatattta
   150301 ccataaaaaa gactaggata aaattcactc ctagccttcg atcattttta ttttgaacga
   150361 caaaaaatat gatgttcaat aacagacgat cttcattcga ttcttgatgt catcttttgt
   150421 tttttttaat atatggataa aaagtttgat tacatcgttt ctattctaga atttggtcga
   150481 ttctcaattc ttcttctggt gagaaatcta aattatccat cattcgaaca ctttcttgta
   150541 actgacttaa ccgacttgct ccgaccagta cacttgtaac agatttttgt cgcaaattcc
   150601 atgcaagggc catttgcgct aatgattgtc ctcgtgatac ggcgattgtt tgcagtgctt
   150661 tgattttttc cagagttgat ccaacttgtt cttctgaaag gaatggtatt tccttacgat
   150721 gtgctctaga atcttcagga ataccatgta gataacgatt tgtcagcaac ccttgagcaa
   150781 gcggactgaa cgtgattgcc cctagccctt cttcttctaa tactggagat agatcgtctt
   150841 ctagtagtgc acgagaaaac atattgtagc gcatctgatg aataatgaac ggtgcttcct
   150901 ttctttttaa aatttcagtc atttttttgt atcttctcca ttatagttgg atataccaat
   150961 atataatgct tttccttgtc ttacaagttg catcaacgct tctgctgttt cttccaaagg
   151021 tgtatcaggg tctgggcgat gatgatagaa gatgtcaaca taatctagcc ccattctttg
   151081 gaaactttgg tcacaacttg atatgatgga tttacgagag ccccattccc catatggccc
   151141 ttcccacata tgataacctg ctttgctaga aataatcagt tcatcacggt aggcttgaaa
   151201 atcttctcta aaaatacgcc caaagttttt ctctgcagct ccagcagggc ctccataatt
   151261 attcgcaagg tcgaaatggg taattcccat gtcgaatgcg cctcttaaaa tctctctttg
   151321 attatggata ggatcataat caccaaaatt ttgccataat ccgagaggag agataaaatc
   151381 ggtaatttta aacctgaatg accggattta cgatattcca ttttttcata acgtgcacta
   151441 tctgcaatat acaatttttc tcctcctcat caaatctttt taaaacgctt tcttgttttc
   151501 tatttttagt ttactacatt ttaaagaaaa ggagttaatc aaaatgattt tttcgtatat
   151561 ttttttgcca tttgtttttt actcgttgat agatcagaaa ttgattacgt gcttgctgga
   151621 tttttttata gcgtttcggt tgttttttgt aaaattgctg atgatagttt tctgctggcc
   151681 aaaacgtacc ggctggttcg atttttgtga cgattggttg gtggaaagtt cctgaactgt
   151741 ctagtttctg ttttgattgt tccgctaatt ctttttgtcg ttcgtcttga taaaaaatca
   151801 ctggacgata ttgcttccct ctatcttgaa attgtccaaa tgtatctgtg ggatcagtaa
   151861 tttgccaata gattgtcagc aactcgctat aacttatttc tcttgtgtca taaatgatct
   151921 ccacagcttc cacatgacct gtgtaaccac cacttacttg atcataattc ggtttttcaa
   151981 catgtccgcc cgtgtatcct gacaaaacag ataggatccc ttttttcgat tcaaacggct
   152041 cgaccataca ccagaaacat ccccctgcaa atactgcacg ttcttgatag tcagcatctt
   152101 gcatggcatg cttggaaaag tcatattttt gctccttatc aaatccttcc gtaatcaata
   152161 aataaaagtc cattacatca ggcgtcagat tcattcggat agctaatgga cgtagtgtta
   152221 cttctagttt tgataactgt tctttaacgg atatattttc tcttgtgtca ttctttgtct
   152281 gaatcaatac ttttcgttcc caatctcgtg tattcggatt caaaatcaga ttataaagtg
   152341 tttgaatgaa tatttgttcc tcatccatag attctcctcc tttccgaaga agacaagcta
   152401 gtgactttag ctgtaattta tcataaagtg aggaaataat cgattgaatc gtatttattc
   152461 aaagaagata agcagcttca gatgatataa gatgatcttt atcttaaaaa gcatactcta
   152521 tggtttggtt taactaaaaa acgacctctg aaaaaaggga tgttctccaa ttctcagaag
   152581 tcgagtaaag atgattcttt tttatgagcg ataataaact tcatccaaaa acagaccttg
   152641 tgcagggacg gtttctcctg catgttgccg cactttgctt tcaaatattt catcgattgt
   152701 ttctatcggc atggcacctg tgccgatttc tagtaatgtc cccatgataa tccgcaccat
   152761 tttatataag aatccgtctc cgacaaaagt aaaatgaagc atttctccct ttcgttcgat
   152821 agataattca tcaatcgtac gcactgtgga tttttttgat tttttcaatg cagaaaaacc
   152881 aatgaaatca tgtgtaccca ctaatttttc gcaagctgca ttcagcttgt ccatatccaa
   152941 ctcttgaggg aaataaaagc tgtggtttcg ctcaaatgct gaaggaatca cgttgttcca
   153001 aacataatag ctgtattttt tgcccaccgc attatatctt gaatggaagc gctcaggcat
   153061 ttcttcgatt cttttgatga caatatcccg cggaaggtaa cgattcataa agtcgatcat
   153121 ttctgccagt ccaatttctg tgtttgtttt aaaatttgct acttgtcctc gcgcatgggt
   153181 gccagcatct gttcttcctg atccaataat ttctatctct tcatttgtca tctgatgcaa
   153241 tactttttcg atttttcctt gaatggtttt atcgtcatct ccaagtcttt gccatcctga
   153301 atatcttttt ccgtcatatt cgattgtcaa cttgatgttt ctcatatttt agtggctcct
   153361 ctgtcttcca tttggtcttc tctctacctt tttaagattg tagcacaaaa tatagctcct
   153421 tgcttctcta agacagaagc tatacaagaa aactgtggaa atatatattt cagaaaaaca
   153481 aaaaacagcc accggatgaa gtatccgctg actgttcaat ttgacggctc aagttttact
   153541 gtttgagatg caagatactc aaccaggcaa tgggcacata attaaagaaa aaactgattc
   153601 tttggcaaaa acctatttta ttcagtaatg gccaagaatt tatagaagga attcttgcca
   153661 gtccataaat cgccgcaaaa agcaaactga tcacagacag tccaaggtat aagtggctta
   153721 cgtccatttg cccatttttt cgatagatca agaaaagaag aactggaaac aataaaaaac
   153781 cactgtaacc taaacctgat ccgatattat ggacccatgt cgagacattc cacgaagatt
   153841 catgggtatt gatactgaac aaacctgtaa agatacaatc acctatacca tagaacgcga
   153901 tggctgctgt aactagggta gctaacacac gagatgtact tacaaatgca gcatacaatg
   153961 caggcaatga caggatgaaa aagatccctg aaaccacaga ccaaataaga aacgcttttc
   154021 ttacaggact ggaaacctct ccaaatacac tgatcacgct cttcatttga tctaattcag
   154081 gataatacaa tcctaatacg tacggagtca aaaaatcact cagcacgcct aataataaaa
   154141 agaaaaaacc aaatttacgt aaaaaatcca tgatacgcct ccaataacaa ttacctatgc
   154201 ttttaattgt tattataaac gactttatct tgatttaaca gaaacctcta tttacacgaa
   154261 catctatata actcattaaa aactcgaatc attttaaaaa tactaaatat ctaacgttca
   154321 acgttcactt aatccatcta aacaatcttt caatttgatt ttttccccac ttcttttacg
   154381 cgcgcctagc tctcctattg cagtaaacaa cagatcactt gacgaattta aggcagtttc
   154441 cattgaatcc tggataacac cgataataaa tccaatacca acgatttgca tcgcgacatc
   154501 attagagata ccaaacaaac tacatgctaa tggaatcaat aacagtgaac cgcccgcaac
   154561 acctgaagct ccacaagcag ctaaagcaga caaaatacat aaaaggactt tcaaaacaaa
   154621 tggtgcttca atccctaaag aatgtacagc agtcaacgtc atcaaggaaa tggtaatcgc
   154681 ggcaccgccc atattgatcg tagcacctaa cgggatcgat atggaataag actcttttgt
   154741 caatttcaat ctttcagcca acatcatgtt tatcgggata tttgcggcag aacttcgggt
   154801 aaagaaagcg ggaagtgcgc tttctttcaa acaaaagaaa atcaatggat agggattttc
   154861 tttaataaac aaaaacgtga ggaatgggta cacaactaat gcgacaaaca gcatcgtacc
   154921 gatcaaaaca agtaaaagct gcagatactc tgccaatcca gcgattccag tcgtagcaat
   154981 tgattgataa accaatccta aaatccctat cggagcaaat gcaataatca cttgtacgac
   155041 ttgtgacaac gctatagata tctgatccac caactctttt gtcggttctg aacgtgctcg
   155101 aaaagctagt cccaacaata cagcccagaa taaaacgcca aggtaattcg catcaataag
   155161 agattgaaca ggattttgtg tgacattcgt caacatagta gataaaacac tttccaaact
   155221 ttgcggtgct ttttcagata ctgtttcttg taaagtaata ggaacagtaa aaattgaact
   155281 tacaatgact gctacaagtg cagaaagcaa tgttcccact aaatataaga tcaaaatagg
   155341 cttcacgaat gtcttattcc caattttatg cttggcaatt gacgccatcg tcaagaaaaa
   155401 aaccagaata ggtgcgattg ccttcaagca actgacaaac aacgtcccca atattgaaat
   155461 aaatgtccac gtggggaaaa agataccaaa caatattccg actaaaatac caacaacaat
   155521 acgttgaact aacgacatat ccaaaaactt ctctaacaaa tgaccaccct ttcacaattt
   155581 taacaatcat tgtatcattt tatctaaaga aactaaaggt gcaattttct aaaaattcta
   155641 ataatacaat tggcaattca tgctcttgca acattcaatt ttagtattgg agggtttatt
   155701 caatctctaa agaagtcgag agaaaactat ttatcgttat tattatagtt atccaagtaa
   155761 aacgtaacta agatgaagga cgaaactaga aatttcatcc ttcatcttaa ttcttagaca
   155821 tagcaatcaa ttaatatttt ccactgagtc tcttctttct ctcactctca ctggtttact
   155881 tacccataaa cgatttgatt aaagccattt ttcaattcat tattcgctgt ctcgttaaag
   155941 taaagataat tatcgggatt cccctgattt tgttgtgtca ccaatacttt tggctgattt
   156001 tgctgaaacc cgaatagata gacgtgcttt ttcagatatg gttctgtctc tgcatcggaa
   156061 tagacggctg tgatttgata gtctgcttga cctgtcccac tttctgacca ttctgcagaa
   156121 acaggcactc caccaatagc catcttccac tccccgttca aaataacttg agggacttta
   156181 agaccatata agtccacact catttgattc gtatagcttt tgtattgttg tcccattgtt
   156241 tggccccatg tagccataaa tgcctctaat tgtgcggatt tgtctgcatt ccacagtgtt
   156301 tgttcgactt gttcgctgct ttctgaagat gaagcctcta cagaagaact tgaagtagat
   156361 gtttgagttg tttcagtcgt tttggaagac tctgacgaag tagaggtatc tgctgtttcc
   156421 gtacttgctg cagttggctt gctctctgtg ctagttgttg tagtagttgc aattgttgct
   156481 ttcgctgttt cttttgttga ttcttttttc gattcattcc cgttggtaca accagctaac
   156541 aaaaaagcta gaccaattgt tactaaaatc ctttttttaa attaaaaaac tcctttcgat
   156601 tactcccact tctttattct atcaaataag caatgtgatt ttattgattt tttgtatttt
   156661 ctcatccatc ttttaaacct tttaaaaact aagaagcacc cgctgatgtt gtctgtaata
   156721 catcagcggg tgcttctttt attttaatct tcgcgatttt ccaatttacc tcacgcttta
   156781 tatttgtatt tgaagaaaca tagactttta gtcatcatcg tcttcctcat ccaaatcttg
   156841 tcggacagtt tttccttgga gtctttgtac ttggtagatg atttctttat tgaaacttaa
   156901 aagttcaaca agcaattgtt tcaagccata tttttcttct ttttcagcta atttgattgc
   156961 ccgtgtgata aagacatttt ggaaatcaaa atcttttgca aagttttcca acattgttga
   157021 ggctggtaaa tatttgtttt gaccatgttc gtaaattttt ccataacgca tgacttcttc
   157081 taaagtagac ggaacgattt cattttcaat cactaactca tgagagattt tattgaacca
   157141 tctcgcttct tgatcagcat attctgaaaa aagggtactt aattcttgcg aagatgtacc
   157201 caaaacatac aattgtgctt ggatcaattt catttcttct aatttaaaat ttgccaatac
   157261 atgccccacc atggcgccag cagttggttt atgatgatcg atatctgctt gttttgtttc
   157321 ttgagcaaat ttttcttcca ctatattcac tgatttacgc ctcttttact tttgttgatt
   157381 ggacttcata acctaatttt tccacaactg cagctaattg ttcagggtgg acttcatctg
   157441 gatcaaagtt tgctttgatt ttgctcgcat taaacaaaac tttcgtattg cttaccccag
   157501 gctgttgaga aaccgcatgt tctatttttt gcatacagct tggacaagct agtgtatcta
   157561 attgcataat catttttttc atcgtagttc ttccttcctt tttcttgata gtcttattct
   157621 agattacagc ttccataaaa aaattgattc ttatcaagtt ttacgatttt tcttctttgc
   157681 tttcgtgtcc aaaatacaat aaacgcatcg cgttaaagat aacgatcaag atactagctt
   157741 cgtgaacgaa catcccacta gccatgtaaa taaacccggc aaataagccg atgagtaaaa
   157801 ataagacgac accaatggca atcactacat tttcacgggt attcaaaaca gttttcttag
   157861 ccaaacggta agcatgaacc aacgatccaa aactagattg catcaagaca acgtcactcg
   157921 tttcgatagc gacatccgtt cctgatccca tagcaatccc gatatcagcc gcagccaaag
   157981 agggagaatc attgattcca tctccaatga aagcaacgtg caatccttgt tcttggtatt
   158041 ttttcacaaa ttgaaccttt tcatctggca ataattcagc atggacttca tcaatgccta
   158101 acatgtcagc tacataatca gcagtcatct gattatcacc tgtcagcatc actaaatgtt
   158161 ttgctcctgc ttgtttcaac atagctaatt gttcagcgac ttctggtcga atcacatctg
   158221 acacaccaat gatttgagtg atttttttgt cgattgctac aataatgact gagctgcctc
   158281 tttgttgtaa ttgatgtaaa tcttgtactt gctttggtgt gagagaaagt ttgtgagcgg
   158341 caatcaattt ggtgttgccc gcacaaactg tatgaccatc aatctcagct gtgattcctt
   158401 gtcccttgat cgtctgatta tctttgactg ctaattgttg aaaatcaatg tctttctcct
   158461 gagcataatg gatcacggcg cgccccagag gatgatcgga taacgtttct aatcgagcca
   158521 ctaaagctaa gctgtcccct tcatcctctg tatagttctt gatagtggat acagcagtag
   158581 ttcctttggt caatgtaccg gttttatcaa agacaaaagt atcgattttg gaaaaagtat
   158641 ccattgcttc accgcctttg actaagatgc cccgtttcgc tccattaccg attcctgcta
   158701 cattcgaaac aggcgcacca atgactaaag cgccaggaca accaagaacc aaaacagtga
   158761 tggctaaacg aaaatcacga ctgatcagac caacaagcaa cgcaataagt aaaacggttg
   158821 gagtataata ctgagaaaat tgatcaatga atttttccgc atgtgatttg gtatcttgtg
   158881 cttcttcgac taattctata attttggcaa aggtcgtatc atctccgacc ttagttgctt
   158941 cgatcgtcac gtagccatct gctaaaatcg ttccagaaaa tacgttatct ccactgattt
   159001 tgacgacttg tcgtgattca cccgtcactg cggcttcatc cgcataccct ttcccgtcaa
   159061 tgactcgtcc gtccacagga atagctccac cagtttttac taagacgata tcgccttctt
   159121 ccacgtcatc gatttccact tcttcggtcg ttccatcttc ttggacaacg ctggcagtcg
   159181 atggggccat ctcggtcaaa gccttgattg attcccgcgt tttggtcaat gttttttgtt
   159241 ccagataact accaaacaaa aacaagaatg taacgatagc tgactccttg tattctccga
   159301 tcataaaggc accaagcaca gcaatagtaa cgagtaaatc aattgagata actttgactt
   159361 ttactgcctg atacgcatgg attataatag gtatgaccgc aataatagaa gctatggcta
   159421 gagcaatgtt atagaacaag acaaatccag taaatttccc gataaaacca aaaataatca
   159481 acacagctga taaggcggtg atatgatttc gatgctcttg gatccacttt tgtaatttca
   159541 tctttctccc tcttttcctt ttcattctta cgagactaag tatagatact tatccatcat
   159601 aaaaaattga ccactatcaa gtttattcaa aaaggcggtt ttcttttggt atactgaatt
   159661 cctacagtca ttaaacgatc atatagaaaa aggaagcgcc gaaacgcttc cttaggtagt
   159721 tctatttttt tattcaaaga taagatgctt tgtcatctta cgactgaaga acaacaatca
   159781 aaaaagggca gcagccactc attcacaaga aatatcgttt tttgatatgg gagttgaagc
   159841 agtggacaaa tatctctact tattagctgg gaataagatc caaaaaagct taatggattt
   159901 tatccaagaa ttggaatgta ctttccacaa aaaattcact cattccattc ttttaaaact
   159961 tttgattcat acagcgtgtc taattgagcg tacattgata aacggtcatg aacttaaaat
   160021 tatatcagaa gatgacacaa gaccttctca tgaaacaatt tttcatgtaa aaaaggcctt
   160081 caaaaatatt gaaacagaat ttgggatcac tgtttcttat gatgaatgtt tctttatcta
   160141 tgatattatc gcatctaaat aatctttttt tatgtaaacg agtattttgg gagcgtcaat
   160201 aattttgtgt aaataaattg tcctcctgca aaataattag ttactcagta aacattgaaa
   160261 ctaatgtatc ggttac
//
LOCUS       DAYNVV010000002       137583 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.002, whole genome shotgun sequence.
ACCESSION   DAYNVV010000002 DAYNVV010000000
VERSION     DAYNVV010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 137583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 137583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..137583
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.002"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            396..788
                     /locus_tag="ACGXWR_000144"
     CDS             396..788
                     /locus_tag="ACGXWR_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFK0801766.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            816..2156
                     /gene="glnA"
                     /locus_tag="ACGXWR_000145"
     CDS             816..2156
                     /gene="glnA"
                     /locus_tag="ACGXWR_000145"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HFK0801767.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            2882..3127
                     /locus_tag="ACGXWR_000146"
     CDS             2882..3127
                     /locus_tag="ACGXWR_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801768.1"
                     /translation="MKEKDCFYDKLYKLLLQVGKSSSLLGGILSIIMFVLFFYLLFHL
                     KFFSNDFLICLGLTLAMFISSLLCGLNFFCTHKGLKK"
     gene            3348..4958
                     /locus_tag="ACGXWR_000147"
     CDS             3348..4958
                     /locus_tag="ACGXWR_000147"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HFK0801769.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(4935..5147)
                     /locus_tag="ACGXWR_000148"
     CDS             complement(4935..5147)
                     /locus_tag="ACGXWR_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801770.1"
                     /translation="MKMKIFKKFFAKNKISNSALIEKSLLLSIFFPTNNNKLEKEKSD
                     KKIAYPLLLLLFSFYQVQKLFCFVIC"
     gene            5250..6119
                     /locus_tag="ACGXWR_000149"
     CDS             5250..6119
                     /locus_tag="ACGXWR_000149"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HFK0801771.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6284..7555
                     /locus_tag="ACGXWR_000150"
     CDS             6284..7555
                     /locus_tag="ACGXWR_000150"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFK0801772.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7552..8847
                     /gene="rho"
                     /locus_tag="ACGXWR_000151"
     CDS             7552..8847
                     /gene="rho"
                     /locus_tag="ACGXWR_000151"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HFK0801773.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8946..9209
                     /locus_tag="ACGXWR_000152"
     CDS             8946..9209
                     /locus_tag="ACGXWR_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HFK0801774.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9654..10103
                     /locus_tag="ACGXWR_000153"
     CDS             9654..10103
                     /locus_tag="ACGXWR_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFK0801775.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            10160..11578
                     /locus_tag="ACGXWR_000154"
     CDS             10160..11578
                     /locus_tag="ACGXWR_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFK0801776.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSISTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11578..12438
                     /locus_tag="ACGXWR_000155"
     CDS             11578..12438
                     /locus_tag="ACGXWR_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFK0801777.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12612..13385
                     /locus_tag="ACGXWR_000156"
     CDS             12612..13385
                     /locus_tag="ACGXWR_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFK0801778.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13532..13897
                     /locus_tag="ACGXWR_000157"
     CDS             13532..13897
                     /locus_tag="ACGXWR_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HFK0801779.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(14045..15253)
                     /locus_tag="ACGXWR_000158"
     CDS             complement(14045..15253)
                     /locus_tag="ACGXWR_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFK0801780.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15272..15550)
                     /locus_tag="ACGXWR_000159"
     CDS             complement(15272..15550)
                     /locus_tag="ACGXWR_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801781.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15743..16399
                     /locus_tag="ACGXWR_000160"
     CDS             15743..16399
                     /locus_tag="ACGXWR_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFK0801782.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16841..17638)
                     /locus_tag="ACGXWR_000161"
     CDS             complement(16841..17638)
                     /locus_tag="ACGXWR_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HFK0801783.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17635..18819)
                     /locus_tag="ACGXWR_000162"
     CDS             complement(17635..18819)
                     /locus_tag="ACGXWR_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HFK0801784.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18844..20091)
                     /locus_tag="ACGXWR_000163"
     CDS             complement(18844..20091)
                     /locus_tag="ACGXWR_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFK0801785.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20306..22051
                     /gene="dnaX"
                     /locus_tag="ACGXWR_000164"
     CDS             20306..22051
                     /gene="dnaX"
                     /locus_tag="ACGXWR_000164"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HFK0801786.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            22071..22385
                     /locus_tag="ACGXWR_000165"
     CDS             22071..22385
                     /locus_tag="ACGXWR_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HFK0801787.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22410..23006
                     /gene="recR"
                     /locus_tag="ACGXWR_000166"
     CDS             22410..23006
                     /gene="recR"
                     /locus_tag="ACGXWR_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HFK0801788.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            23070..23714
                     /gene="tmk"
                     /locus_tag="ACGXWR_000167"
     CDS             23070..23714
                     /gene="tmk"
                     /locus_tag="ACGXWR_000167"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFK0801789.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23729..24058
                     /locus_tag="ACGXWR_000168"
     CDS             23729..24058
                     /locus_tag="ACGXWR_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HFK0801790.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            24072..25010
                     /gene="holB"
                     /locus_tag="ACGXWR_000169"
     CDS             24072..25010
                     /gene="holB"
                     /locus_tag="ACGXWR_000169"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HFK0801791.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            25046..25870
                     /locus_tag="ACGXWR_000170"
     CDS             25046..25870
                     /locus_tag="ACGXWR_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HFK0801792.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25863..26210
                     /locus_tag="ACGXWR_000171"
     CDS             25863..26210
                     /locus_tag="ACGXWR_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HFK0801793.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26279..27151
                     /gene="rsmI"
                     /locus_tag="ACGXWR_000172"
     CDS             26279..27151
                     /gene="rsmI"
                     /locus_tag="ACGXWR_000172"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HFK0801794.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27260..28381
                     /gene="dinB"
                     /locus_tag="ACGXWR_000173"
     CDS             27260..28381
                     /gene="dinB"
                     /locus_tag="ACGXWR_000173"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HFK0801795.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28435..29037)
                     /gene="nrdG"
                     /locus_tag="ACGXWR_000174"
     CDS             complement(28435..29037)
                     /gene="nrdG"
                     /locus_tag="ACGXWR_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HFK0801796.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29352..31541)
                     /gene="nrdD"
                     /locus_tag="ACGXWR_000175"
     CDS             complement(29352..31541)
                     /gene="nrdD"
                     /locus_tag="ACGXWR_000175"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HFK0801797.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31867..32634
                     /locus_tag="ACGXWR_000176"
     CDS             31867..32634
                     /locus_tag="ACGXWR_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0801798.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32624..34666
                     /locus_tag="ACGXWR_000177"
     CDS             32624..34666
                     /locus_tag="ACGXWR_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0801799.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34947..35096
                     /locus_tag="ACGXWR_000178"
     CDS             34947..35096
                     /locus_tag="ACGXWR_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HFK0801800.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            35107..36621
                     /gene="dltA"
                     /locus_tag="ACGXWR_000179"
     CDS             35107..36621
                     /gene="dltA"
                     /locus_tag="ACGXWR_000179"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HFK0801801.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36618..37823
                     /gene="dltB"
                     /locus_tag="ACGXWR_000180"
     CDS             36618..37823
                     /gene="dltB"
                     /locus_tag="ACGXWR_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HFK0801802.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37868..38101
                     /gene="dltC"
                     /locus_tag="ACGXWR_000181"
     CDS             37868..38101
                     /gene="dltC"
                     /locus_tag="ACGXWR_000181"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HFK0801803.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            38104..39372
                     /gene="dltD"
                     /locus_tag="ACGXWR_000182"
     CDS             38104..39372
                     /gene="dltD"
                     /locus_tag="ACGXWR_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HFK0801804.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39513..40595
                     /locus_tag="ACGXWR_000183"
     CDS             39513..40595
                     /locus_tag="ACGXWR_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HFK0801805.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40595..41398
                     /locus_tag="ACGXWR_000184"
     CDS             40595..41398
                     /locus_tag="ACGXWR_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFK0801806.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41468..42208
                     /locus_tag="ACGXWR_000185"
     CDS             41468..42208
                     /locus_tag="ACGXWR_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFK0801807.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42219..43223
                     /locus_tag="ACGXWR_000186"
     CDS             42219..43223
                     /locus_tag="ACGXWR_000186"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017118 - lipoyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HFK0801808.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43268..45112)
                     /locus_tag="ACGXWR_000187"
     CDS             complement(43268..45112)
                     /locus_tag="ACGXWR_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801809.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            45324..45842
                     /locus_tag="ACGXWR_000188"
     CDS             45324..45842
                     /locus_tag="ACGXWR_000188"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFK0801810.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            45970..46653
                     /locus_tag="ACGXWR_000189"
     CDS             45970..46653
                     /locus_tag="ACGXWR_000189"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HFK0801811.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            46962..47035
                     /locus_tag="ACGXWR_000190"
     tRNA            46962..47035
                     /locus_tag="ACGXWR_000190"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46996..46998,aa:Arg,seq:tct)
     gene            47194..47553
                     /locus_tag="ACGXWR_000191"
     CDS             47194..47553
                     /locus_tag="ACGXWR_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HFK0801812.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            47676..49307
                     /locus_tag="ACGXWR_000192"
     CDS             47676..49307
                     /locus_tag="ACGXWR_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HFK0801813.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(49369..50010)
                     /locus_tag="ACGXWR_000193"
     CDS             complement(49369..50010)
                     /locus_tag="ACGXWR_000193"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFK0801814.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    50196..50272
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            50292..50600
                     /gene="rplU"
                     /locus_tag="ACGXWR_000194"
     CDS             50292..50600
                     /gene="rplU"
                     /locus_tag="ACGXWR_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HFK0801815.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            50627..50971
                     /locus_tag="ACGXWR_000195"
     CDS             50627..50971
                     /locus_tag="ACGXWR_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HFK0801816.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            50984..51277
                     /gene="rpmA"
                     /locus_tag="ACGXWR_000196"
     CDS             50984..51277
                     /gene="rpmA"
                     /locus_tag="ACGXWR_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HFK0801817.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            51711..54518
                     /locus_tag="ACGXWR_000197"
     CDS             51711..54518
                     /locus_tag="ACGXWR_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFK0801818.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            54709..55200
                     /locus_tag="ACGXWR_000198"
     CDS             54709..55200
                     /locus_tag="ACGXWR_000198"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFK0801819.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            55303..56292
                     /locus_tag="ACGXWR_000199"
     CDS             55303..56292
                     /locus_tag="ACGXWR_000199"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFK0801820.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            56325..57128
                     /locus_tag="ACGXWR_000200"
     CDS             56325..57128
                     /locus_tag="ACGXWR_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HFK0801821.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            57149..58063
                     /locus_tag="ACGXWR_000201"
     CDS             57149..58063
                     /locus_tag="ACGXWR_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFK0801822.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            58146..58520
                     /locus_tag="ACGXWR_000202"
     CDS             58146..58520
                     /locus_tag="ACGXWR_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HFK0801823.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            58659..58904
                     /locus_tag="ACGXWR_000203"
     CDS             58659..58904
                     /locus_tag="ACGXWR_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFK0801824.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            59076..60140
                     /locus_tag="ACGXWR_000204"
     CDS             59076..60140
                     /locus_tag="ACGXWR_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFK0801825.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            60386..60811
                     /locus_tag="ACGXWR_000205"
     CDS             60386..60811
                     /locus_tag="ACGXWR_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFK0801826.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            60804..61253
                     /gene="nusB"
                     /locus_tag="ACGXWR_000206"
     CDS             60804..61253
                     /gene="nusB"
                     /locus_tag="ACGXWR_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HFK0801827.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            61350..62204
                     /locus_tag="ACGXWR_000207"
     CDS             61350..62204
                     /locus_tag="ACGXWR_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HFK0801828.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            62205..63542
                     /gene="xseA"
                     /locus_tag="ACGXWR_000208"
     CDS             62205..63542
                     /gene="xseA"
                     /locus_tag="ACGXWR_000208"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HFK0801829.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            63547..63771
                     /locus_tag="ACGXWR_000209"
     CDS             63547..63771
                     /locus_tag="ACGXWR_000209"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HFK0801830.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            63773..64663
                     /locus_tag="ACGXWR_000210"
     CDS             63773..64663
                     /locus_tag="ACGXWR_000210"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFK0801831.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            64672..65490
                     /locus_tag="ACGXWR_000211"
     CDS             64672..65490
                     /locus_tag="ACGXWR_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HFK0801832.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            65597..66046
                     /locus_tag="ACGXWR_000212"
     CDS             65597..66046
                     /locus_tag="ACGXWR_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFK0801833.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            66064..67746
                     /gene="recN"
                     /locus_tag="ACGXWR_000213"
     CDS             66064..67746
                     /gene="recN"
                     /locus_tag="ACGXWR_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HFK0801834.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(67801..67917)
                     /locus_tag="ACGXWR_000214"
     CDS             complement(67801..67917)
                     /locus_tag="ACGXWR_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HFK0801835.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(67990..68946)
                     /locus_tag="ACGXWR_000215"
     CDS             complement(67990..68946)
                     /locus_tag="ACGXWR_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFK0801836.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            69117..69485
                     /locus_tag="ACGXWR_000216"
     CDS             69117..69485
                     /locus_tag="ACGXWR_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HFK0801837.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            69655..70086
                     /gene="mraZ"
                     /locus_tag="ACGXWR_000217"
     CDS             69655..70086
                     /gene="mraZ"
                     /locus_tag="ACGXWR_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HFK0801838.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            70107..71066
                     /gene="rsmH"
                     /locus_tag="ACGXWR_000218"
     CDS             70107..71066
                     /gene="rsmH"
                     /locus_tag="ACGXWR_000218"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HFK0801839.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            71071..71478
                     /gene="ftsL"
                     /locus_tag="ACGXWR_000219"
     CDS             71071..71478
                     /gene="ftsL"
                     /locus_tag="ACGXWR_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HFK0801840.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRIRKVK"
     gene            71479..73671
                     /locus_tag="ACGXWR_000220"
     CDS             71479..73671
                     /locus_tag="ACGXWR_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFK0801841.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            73697..74659
                     /gene="mraY"
                     /locus_tag="ACGXWR_000221"
     CDS             73697..74659
                     /gene="mraY"
                     /locus_tag="ACGXWR_000221"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HFK0801842.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            74673..76034
                     /gene="murD"
                     /locus_tag="ACGXWR_000222"
     CDS             74673..76034
                     /gene="murD"
                     /locus_tag="ACGXWR_000222"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HFK0801843.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            76060..77148
                     /gene="murG"
                     /locus_tag="ACGXWR_000223"
     CDS             76060..77148
                     /gene="murG"
                     /locus_tag="ACGXWR_000223"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HFK0801844.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            77163..78383
                     /locus_tag="ACGXWR_000224"
     CDS             77163..78383
                     /locus_tag="ACGXWR_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HFK0801845.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            78539..79864
                     /gene="ftsA"
                     /locus_tag="ACGXWR_000225"
     CDS             78539..79864
                     /gene="ftsA"
                     /locus_tag="ACGXWR_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HFK0801846.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            79887..81128
                     /gene="ftsZ"
                     /locus_tag="ACGXWR_000226"
     CDS             79887..81128
                     /gene="ftsZ"
                     /locus_tag="ACGXWR_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFK0801847.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            81145..81822
                     /locus_tag="ACGXWR_000227"
     CDS             81145..81822
                     /locus_tag="ACGXWR_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HFK0801848.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            81836..82435
                     /locus_tag="ACGXWR_000228"
     CDS             81836..82435
                     /locus_tag="ACGXWR_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HFK0801849.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            82516..82737
                     /locus_tag="ACGXWR_000229"
     CDS             82516..82737
                     /locus_tag="ACGXWR_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HFK0801850.1"
                     /translation="MVYALLSWFPGGYQSGLGRLLAKICEPYISLFDRLPLRIGPLDF
                     TILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            82786..83568
                     /locus_tag="ACGXWR_000230"
     CDS             82786..83568
                     /locus_tag="ACGXWR_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HFK0801851.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            83589..84296
                     /locus_tag="ACGXWR_000231"
     CDS             83589..84296
                     /locus_tag="ACGXWR_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HFK0801852.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            84558..87356
                     /gene="ileS"
                     /locus_tag="ACGXWR_000232"
     CDS             84558..87356
                     /gene="ileS"
                     /locus_tag="ACGXWR_000232"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HFK0801853.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(87405..88931)
                     /gene="zwf"
                     /locus_tag="ACGXWR_000233"
     CDS             complement(87405..88931)
                     /gene="zwf"
                     /locus_tag="ACGXWR_000233"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HFK0801854.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(88946..89593)
                     /locus_tag="ACGXWR_000234"
     CDS             complement(88946..89593)
                     /locus_tag="ACGXWR_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFK0801855.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(89777..90106)
                     /locus_tag="ACGXWR_000235"
     CDS             complement(89777..90106)
                     /locus_tag="ACGXWR_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HFK0801856.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            90283..91011
                     /gene="sfsA"
                     /locus_tag="ACGXWR_000236"
     CDS             90283..91011
                     /gene="sfsA"
                     /locus_tag="ACGXWR_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HFK0801857.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            91027..92040
                     /locus_tag="ACGXWR_000237"
     CDS             91027..92040
                     /locus_tag="ACGXWR_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFK0801858.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            92040..93317
                     /locus_tag="ACGXWR_000238"
     CDS             92040..93317
                     /locus_tag="ACGXWR_000238"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFK0801859.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            93380..96082
                     /locus_tag="ACGXWR_000239"
     CDS             93380..96082
                     /locus_tag="ACGXWR_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFK0801860.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            96234..96551
                     /locus_tag="ACGXWR_000240"
     CDS             96234..96551
                     /locus_tag="ACGXWR_000240"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFK0801861.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            96581..96901
                     /locus_tag="ACGXWR_000241"
     CDS             96581..96901
                     /locus_tag="ACGXWR_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFK0801862.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            97009..98469
                     /locus_tag="ACGXWR_000242"
     CDS             97009..98469
                     /locus_tag="ACGXWR_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFK0801863.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            98537..98758
                     /locus_tag="ACGXWR_000243"
     CDS             98537..98758
                     /locus_tag="ACGXWR_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801864.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            98789..98971
                     /locus_tag="ACGXWR_000244"
     CDS             98789..98971
                     /locus_tag="ACGXWR_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HFK0801865.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            98971..99384
                     /locus_tag="ACGXWR_000245"
     CDS             98971..99384
                     /locus_tag="ACGXWR_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HFK0801866.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            99507..100688
                     /locus_tag="ACGXWR_000246"
     CDS             99507..100688
                     /locus_tag="ACGXWR_000246"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFK0801867.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(100759..100923)
                     /locus_tag="ACGXWR_000247"
     CDS             complement(100759..100923)
                     /locus_tag="ACGXWR_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801868.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            101077..101150
                     /locus_tag="ACGXWR_000248"
     tRNA            101077..101150
                     /locus_tag="ACGXWR_000248"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:101111..101113,aa:Arg,seq:cct)
     gene            complement(101219..102358)
                     /locus_tag="ACGXWR_000249"
     CDS             complement(101219..102358)
                     /locus_tag="ACGXWR_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFK0801869.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            102530..102664
                     /locus_tag="ACGXWR_000250"
     CDS             102530..102664
                     /locus_tag="ACGXWR_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801870.1"
                     /translation="MIKVIFKRITELPEFRLFVDYWYVWFFIVALLIGLDVILERKLK
                     "
     gene            complement(102657..103292)
                     /locus_tag="ACGXWR_000251"
     CDS             complement(102657..103292)
                     /locus_tag="ACGXWR_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801871.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(103405..104040)
                     /locus_tag="ACGXWR_000252"
     CDS             complement(103405..104040)
                     /locus_tag="ACGXWR_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HFK0801872.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(104074..104535)
                     /locus_tag="ACGXWR_000253"
     CDS             complement(104074..104535)
                     /locus_tag="ACGXWR_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HFK0801873.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(104665..105096)
                     /locus_tag="ACGXWR_000254"
     CDS             complement(104665..105096)
                     /locus_tag="ACGXWR_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFK0801874.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(105114..105434)
                     /locus_tag="ACGXWR_000255"
     CDS             complement(105114..105434)
                     /locus_tag="ACGXWR_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFK0801875.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            105733..106509
                     /locus_tag="ACGXWR_000256"
     CDS             105733..106509
                     /locus_tag="ACGXWR_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HFK0801876.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            106524..106727
                     /locus_tag="ACGXWR_000257"
     CDS             106524..106727
                     /locus_tag="ACGXWR_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0801877.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            106743..107081
                     /locus_tag="ACGXWR_000258"
     CDS             106743..107081
                     /locus_tag="ACGXWR_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HFK0801878.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            107068..107247
                     /locus_tag="ACGXWR_000259"
     CDS             107068..107247
                     /locus_tag="ACGXWR_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801879.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(107290..107760)
                     /locus_tag="ACGXWR_000260"
     CDS             complement(107290..107760)
                     /locus_tag="ACGXWR_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801880.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            107847..108545
                     /locus_tag="ACGXWR_000261"
     CDS             107847..108545
                     /locus_tag="ACGXWR_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HFK0801881.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            108723..109064
                     /locus_tag="ACGXWR_000262"
     CDS             108723..109064
                     /locus_tag="ACGXWR_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801882.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            109057..109728
                     /locus_tag="ACGXWR_000263"
     CDS             109057..109728
                     /locus_tag="ACGXWR_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HFK0801883.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            109734..110420
                     /locus_tag="ACGXWR_000264"
     CDS             109734..110420
                     /locus_tag="ACGXWR_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HFK0801884.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            110423..111172
                     /locus_tag="ACGXWR_000265"
     CDS             110423..111172
                     /locus_tag="ACGXWR_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0801885.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            111184..111453
                     /locus_tag="ACGXWR_000266"
     CDS             111184..111453
                     /locus_tag="ACGXWR_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801886.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            111458..111622
                     /locus_tag="ACGXWR_000267"
     CDS             111458..111622
                     /locus_tag="ACGXWR_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801887.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            111615..111917
                     /locus_tag="ACGXWR_000268"
     CDS             111615..111917
                     /locus_tag="ACGXWR_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801888.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            111914..112075
                     /locus_tag="ACGXWR_000269"
     CDS             111914..112075
                     /locus_tag="ACGXWR_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFK0801889.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            112072..112377
                     /locus_tag="ACGXWR_000270"
     CDS             112072..112377
                     /locus_tag="ACGXWR_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801890.1"
                     /translation="MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            112377..112733
                     /locus_tag="ACGXWR_000271"
     CDS             112377..112733
                     /locus_tag="ACGXWR_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HFK0801891.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            112693..112938
                     /locus_tag="ACGXWR_000272"
     CDS             112693..112938
                     /locus_tag="ACGXWR_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801892.1"
                     /translation="MIKKLVQFSMDLYDIESGATLSVESDHLIINFGGKRQIILWVVD
                     DVLFPEIVHDFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            112935..113354
                     /locus_tag="ACGXWR_000273"
     CDS             112935..113354
                     /locus_tag="ACGXWR_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HFK0801893.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVTGNIYENSELLEEQR"
     gene            113351..113908
                     /locus_tag="ACGXWR_000274"
     CDS             113351..113908
                     /locus_tag="ACGXWR_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HFK0801894.1"
                     /translation="MNKQEAIKKLESIKAIGNDAIAACYNESINSGITLMKKIDEPQK
                     PVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLWAIKNADGNYLTKCALWGKDGVNYSFECNPSHRL
                     LFTDKATADAAALLVNGTVEEVVER"
     gene            113905..114201
                     /locus_tag="ACGXWR_000275"
     CDS             113905..114201
                     /locus_tag="ACGXWR_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801895.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            114278..114691
                     /locus_tag="ACGXWR_000276"
     CDS             114278..114691
                     /locus_tag="ACGXWR_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFK0801896.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIETERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            115000..115152
                     /locus_tag="ACGXWR_000277"
     CDS             115000..115152
                     /locus_tag="ACGXWR_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801897.1"
                     /translation="MKLSVEGTPEEIQELLQAIGSSKEQKVSVSNSDIDGICNCLNRE
                     KISNPY"
     gene            complement(115149..115424)
                     /locus_tag="ACGXWR_000278"
     CDS             complement(115149..115424)
                     /locus_tag="ACGXWR_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801898.1"
                     /translation="MYKPYMISYDLNNPGQKYDKVFEIIKEFGAYIKLQKSFWLVKTN
                     LNPNQMCEKLNTVLDNNDSLFICELQKNYQGRATEENWKFINEHIFS"
     gene            115920..116084
                     /locus_tag="ACGXWR_000279"
     CDS             115920..116084
                     /locus_tag="ACGXWR_000279"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801899.1"
                     /translation="MPATLNAYDGYDYRKKIVKKLYGATYGNVVSVLSVHHQASVTVA
                     EVEDAAVNGE"
     gene            116280..116447
                     /locus_tag="ACGXWR_000280"
     CDS             116280..116447
                     /locus_tag="ACGXWR_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFK0801900.1"
                     /translation="MYRPQYLEQKYEVITVHKGNGEKVYEYRRPIKSDTYKRKENNEV
                     IPLYGKRIAKH"
     gene            116473..116817
                     /locus_tag="ACGXWR_000281"
     CDS             116473..116817
                     /locus_tag="ACGXWR_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HFK0801901.1"
                     /translation="MTEEFYRWLLQLTREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            116822..117103
                     /locus_tag="ACGXWR_000282"
     CDS             116822..117103
                     /locus_tag="ACGXWR_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801902.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            117206..117520
                     /locus_tag="ACGXWR_000283"
     CDS             117206..117520
                     /locus_tag="ACGXWR_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HFK0801903.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            117498..119192
                     /locus_tag="ACGXWR_000284"
     CDS             117498..119192
                     /locus_tag="ACGXWR_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFK0801904.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            119212..120390
                     /locus_tag="ACGXWR_000285"
     CDS             119212..120390
                     /locus_tag="ACGXWR_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFK0801905.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            120353..121039
                     /locus_tag="ACGXWR_000286"
     CDS             120353..121039
                     /locus_tag="ACGXWR_000286"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HFK0801906.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            121039..122199
                     /locus_tag="ACGXWR_000287"
     CDS             121039..122199
                     /locus_tag="ACGXWR_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFK0801907.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            122209..123084
                     /locus_tag="ACGXWR_000288"
     CDS             122209..123084
                     /locus_tag="ACGXWR_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801908.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            123081..123392
                     /locus_tag="ACGXWR_000289"
     CDS             123081..123392
                     /locus_tag="ACGXWR_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801909.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            123382..123735
                     /locus_tag="ACGXWR_000290"
     CDS             123382..123735
                     /locus_tag="ACGXWR_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFK0801910.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            123725..124126
                     /locus_tag="ACGXWR_000291"
     CDS             123725..124126
                     /locus_tag="ACGXWR_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801911.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            124119..124523
                     /locus_tag="ACGXWR_000292"
     CDS             124119..124523
                     /locus_tag="ACGXWR_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801912.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            124535..125143
                     /locus_tag="ACGXWR_000293"
     CDS             124535..125143
                     /locus_tag="ACGXWR_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFK0801913.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            125163..125525
                     /locus_tag="ACGXWR_000294"
     CDS             125163..125525
                     /locus_tag="ACGXWR_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801914.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            125528..125710
                     /locus_tag="ACGXWR_000295"
     CDS             125528..125710
                     /locus_tag="ACGXWR_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801915.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            125727..129158
                     /locus_tag="ACGXWR_000296"
     CDS             125727..129158
                     /locus_tag="ACGXWR_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFK0801916.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDFIVAIGGLTAAFGILLPAILAVSYLFGPMML
                     IIGGIIAVIAGVIVAIKNWGAITDWFSGLWKKFTDWLGDTWESIKDGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQTFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPEFIMEGSF
                     NPLKGQIPHLRVKWHAKGGIFTKPTLLGGMNGVGEAGPEAVLPLKRSVLQEIGDRILS
                     STSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKIQNDNASAWR"
     gene            129209..129946
                     /locus_tag="ACGXWR_000297"
     CDS             129209..129946
                     /locus_tag="ACGXWR_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFK0801917.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            129956..132247
                     /locus_tag="ACGXWR_000298"
     CDS             129956..132247
                     /locus_tag="ACGXWR_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFK0801918.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVDGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDNGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            132271..134397
                     /locus_tag="ACGXWR_000299"
     CDS             132271..134397
                     /locus_tag="ACGXWR_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801919.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGDYDYSENPNLMPYITEPWVG
                     PLLGNGHTVKDSVKRVITHTKTRTANSGDILSLGLGIPCTAEANNRYLITTLRPSTTY
                     TLSVTMSVGSDWTGETNTIGVRLRYLNEQGGIELPINALIPANVERDKMVTHTFTGIT
                     KDNVTSITNCYVEIFSLNSEYKGTVSVSYDVKLKAHYPNLLDGPYWLGKVPLGENIAD
                     PTVVFPHKTSEYMVYGRRNTENYIADQTYTISMKATKLTVQSFAVYIAAGRVKVGDMK
                     PTEGLANTWELTFTVTKQHIDSGVTNYLEIYQYPSATKGAVQIEWLKLEKGNTRTPNI
                     SEYKYRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINS
                     QLTASINEVDTTAKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKL
                     YREGKTVSIYFVALNGKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSI
                     GADGAIKWRRNSSYGSDYTFAITYTI"
     gene            134414..134563
                     /locus_tag="ACGXWR_000300"
     CDS             134414..134563
                     /locus_tag="ACGXWR_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801920.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            134560..135006
                     /locus_tag="ACGXWR_000301"
     CDS             134560..135006
                     /locus_tag="ACGXWR_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801921.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            135008..135145
                     /locus_tag="ACGXWR_000302"
     CDS             135008..135145
                     /locus_tag="ACGXWR_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HFK0801922.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            135183..135476
                     /locus_tag="ACGXWR_000303"
     CDS             135183..135476
                     /locus_tag="ACGXWR_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801923.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERRK"
     gene            135473..135697
                     /locus_tag="ACGXWR_000304"
     CDS             135473..135697
                     /locus_tag="ACGXWR_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HFK0801924.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            135694..136719
                     /locus_tag="ACGXWR_000305"
     CDS             135694..136719
                     /locus_tag="ACGXWR_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition family protein"
                     /protein_id="HFK0801925.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
     gene            136909..136982
                     /locus_tag="ACGXWR_000306"
     tRNA            136909..136982
                     /locus_tag="ACGXWR_000306"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:136943..136945,aa:Ile,seq:cat)
BASE COUNT        45772 a        22932 c        28794 g        40085 t
ORIGIN      
        1 cttcgcaacg atagcaaccg gagtttcttg atgaaaatat gcttctatca ttacaagctc
       61 gtttggtgta agatgggtat aagtcattta tgttcactct ccttgtatgc tttagcgggt
      121 attacaattt gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg
      181 gcgcaataaa aacactaata aaggatagta cagtataata aaaaataaaa ggtatctggt
      241 acgaaaatca actagatacc ttttttgtgt tcttattttt ttgttatttt ataaaaaata
      301 gagatctcat gttagaaaac ctaacatatg cagttgacaa tatttttttt aattggtaca
      361 ctttagccaa cttataaaac gaaaggggac gtctgatggg agaaaaggaa ttgcgccgat
      421 ctatgtccgt atttccaatt ggtacagtta tgaagctgac tgatttgtct gctcggcaaa
      481 ttcgctatta tgaagaacaa gatttagttc atccggaacg aagcgaagga aaccgacgta
      541 tgtattcgct gaatgatatt gatatgttgc ttgagattaa agactatctt tcagagggat
      601 tgaatatggc tgggatcaaa cgtgtatacg aaatggcaca ggcgaaaaaa caagaagcaa
      661 aaaacaagaa gccgttgaca gatcatgacg ttcgacaaat ttttcgtgat gagattttgg
      721 cgcaaggtgg gttaagcaaa acaggtcatt atcagtcgca aggattgcaa agacaattct
      781 ttgactgaat aaattaaaaa aggaagaggg ataccatggt aaagaaacag ataacaggtg
      841 aagaaatcaa acgaatcatt gaggaagaaa acgtacgatt tttacgattg atgttcacag
      901 acatcttagg tacgatcaaa aatgtagaag ttccagtgag ccagatcgac aaagtattag
      961 aaaataaaat gatgtttgac ggttcttcga ttgaaggatt tgttcgaatt gaagaaagcg
     1021 atatgtattt gtatccagat ctctccactt ggatgatctt cccgtgggaa agtgctcatg
     1081 gaaaagttgc tcgtttaatt tgtgatatct ataatccgga tgggacacca tttgccggcg
     1141 atcctcgcgg gaatttgaaa cgagcattga aagatatgcg cgaccttggt tttacctctt
     1201 tcaatttagg acctgaacca gaattcttct tatttaaatt agacgaagac ggtgggatca
     1261 caacgacctt gaatgataaa ggtggttatt ttgattttgc accaacagat ttaggtgaaa
     1321 attgccgccg tgacatcgtg ttggaattag aaagtctagg ctttgaagtg gaagcttcac
     1381 atcatgaagt agcgccagga cagcatgaaa ttgactttaa atatgcagat gtggtagatg
     1441 cttgtgataa tatccaaacc ttcaagctcg ttgtcaaaac gattgcacgc aagcatggac
     1501 ttcacgcgac tttcatgccg aaaccgttat ttgggatcaa tggttctggt atgcattgca
     1561 atatgtcttt gttcaatgat gaaggaaatg ttttctatga taaagacggt gaattggaac
     1621 taagtgaaac agcttatcat ttcttaggtg gtttgctgaa acatgctcgt gcctacacag
     1681 ccgtttgcaa tccaacagtc aattcttata aacgtctcgt tccaggttat gaagcgcctg
     1741 tttatgtcgc atggagtggc cgtaatcgtt cgccattagt acgtgtacca gaatctcgcg
     1801 gtttatccac acgtttggaa ttgcggtcag ttgatccatc tgcaaaccca tacttggcaa
     1861 tggcagtatt gttgcaagca ggactagacg gtatccgtaa tcagatcaca ccgccagcag
     1921 ctgttgaccg taacatttat gtaatggatg aggaagaaag agaagctgca catatccagg
     1981 acttaccttc aactatccat aatgctatca aagaattgcg taaggataat gtaatgattg
     2041 acgcattagg acaacatatc ttctcaaatt ttgttgaagc aaaacgtctc gaatgggcgg
     2101 cattcagaca aactgtttcc gagtgggaaa gagaacaata tctagaactt tattaaaaca
     2161 ggaataccgt gaattagagg ctgtgaaatc agcgttttga cctgagtatt agagaaacta
     2221 acggaaaaat agttcctcat attttgccgt tttttgagct aataccgagg gtcagctgat
     2281 tgaacaccgt ttagtggaga ggttgtgaaa aagctgccct gcaacaagta ataagaatag
     2341 ccaagcaaaa acagcttttc ttgtttttga attggctgaa cttattaccg cagatgcaag
     2401 cttttgaaca ccgtttacca agaggttttg aaaaagacgt ttagtttcga gtattaagaa
     2461 aaattttgtg aaaatggctt tctacatttt tgcataaatt tggcttaata ccgagaaact
     2521 ggcttttgaa taccgtttat ccagaggttg tgagcctacc atttaactcc gaatcacaag
     2581 aaataatttc aaaaacagct tctcatgttt gatggatatt gtgacttgtg accgaggagt
     2641 tggcaggaga acaccgttta tttagaaata aggaggcacg acttttgtcg catctcctta
     2701 ttttttactt atgtgattcg ttaccttcaa tgaatcccta caaggcactt ttgttgaaaa
     2761 aaaggtcatc tttgaaaaaa ttagtggaat tgttttgttt ttgatattat ttaatagaaa
     2821 agatatgcca aaaatccgag aactgtggac tacgtttttt acgtaaagga ggtaaataag
     2881 ggtgaaagaa aaagattgtt tctacgataa gctatataaa ctgttgctgc aagtaggaaa
     2941 aagtagttct ttgttaggtg ggatattatc tatcataatg tttgttttat ttttttatct
     3001 attatttcac ttaaaatttt tcagtaacga ttttctgatt tgcttaggtt taacgttagc
     3061 tatgtttata tcaagcttat tatgtgggtt aaattttttt tgcactcata aaggacttaa
     3121 gaaataattt ctcaaaggat atcgaaaaag aaaaaattgt aagcggatag tattcatttg
     3181 agtacttgac tttcccttag tcagcttgta ttatacacct tgggcaccct tttagagggt
     3241 cagaagttta cagaatttcg gctccctatt cttattgaag aatagggagc tttgtttatt
     3301 gtctgagact tttcctgcac ataaattaaa aaggagtttt tgaacttatg acaaaatata
     3361 tttttgtgac cggcggtgtc gtttcatcaa tcggaaaagg gattgttgca gcttctttag
     3421 gacgcttatt gaaaaaccgc ggcttaaaag taactatcca aaaatttgat ccatacatca
     3481 acgtggatcc ggggacgatg agcccatatc agcacggaga agtattcgta acagatgatg
     3541 gtgctgaaac agatttggat ctgggccact acgaacgttt tattgacatc aatttgaaca
     3601 aatactccaa cgtgacgaca ggaaaaatct attctgaagt tttgcgtaaa gaacgtaagg
     3661 gcgaatactt gggagcaact gttcaagtta ttcctcatat tacaaatgag atcaaagaaa
     3721 aaatcatgcg agcagctaaa atgactgatt cagatgtgat cattacagaa gtagggggaa
     3781 cagtagggga tatagaatct ttgccattcc ttgaagcact tcgtcaaatg aaagcagatg
     3841 tcggtacaga taatgttatg tatatccata caacattgat tccttacttg aaagctgctg
     3901 gagaaatgaa aactaaacca acgcagcaca gtgtaaaaga gctacgtggt ttaggtatcc
     3961 aaccgaatat tttggtggta cgtacagagc aacctgtttc tcaaagcgtg aaaaacaaat
     4021 tggcacaatt ttgtgatgtc gaaccagaag cagttatcga gtcgccagat gtagatacac
     4081 tttactccat cccattagtt ttacaagcac aaggaatgga tcaaattgtt tgcgaccatt
     4141 taaaactaga tacaccagaa gcagacatga cagaatggaa agaattagaa gaacgtgtct
     4201 tgaacttgaa gaaaaaagta cggattgcgc ttgtcggtaa atatgtcgag ttaccagatg
     4261 catatatctc agtagttgaa gcattgaaac attctggttt cgcctataat tcagacatcg
     4321 agatcgattg gatcaaagca caagaattaa cgagagaaaa tgtagaagaa cgtttgaaag
     4381 acgcagatgg aatcttggtt cctggtggat ttggtgatcg cggagtagaa gggaaaatcg
     4441 aagcgattcg ttatgctcgc gaaaatgacg ttccgttttt aggtatttgt cttggtatgc
     4501 agatggcttg tgtcgaattt gcacgtaacg tcgttggatt agaagatgcg tcatcagctg
     4561 aaacgaatcc agatacagca aacaatatta ttgatttaat ggctgatcag gaaaacatcg
     4621 agaatttggg tggaacttta cgccttggat tatacccatg taaaatcaaa aaaggaacga
     4681 agacggctga agcatatgat ggagccgatg ttgtgcaaga acgtcaccgt caccgctatg
     4741 agttcaataa caaatatcgt caattgtttg aagaacaagg gctagtcttt tcaggtgtct
     4801 caccagataa ccgtttagta gaaatcgtag agctgccaga gaaaaaattc tttgtgggat
     4861 gccaattcca cccagaattg atttctcgtc caaatcgccc gcaaaaatta atcaaagcat
     4921 ttgtcggagc atcattagca gatcacgaaa caaaataatt tttgaacttg atagaaagag
     4981 aaaagtagca agagaagggg ataagcaatt ttcttgtcac ttttctcttt ttctaatttg
     5041 ttattatttg taggaaaaaa gatagaaagc aaaagacttt tttcgattaa agcgctattg
     5101 gatattttat tttttgcaaa aaacttcttg aaaattttca ttttcattga ttttagtaga
     5161 aaactaccga aatgtttggt aaaatagggt cgttggttaa gaattgtctt aacaaattta
     5221 gttttacaaa acttaggagg aattttatta tgccagtagt atcaggagct gaatttttaa
     5281 aagctgctcg taaaggcggt tacgctgtcg gcggattcaa cacaaacaac ttggaatgga
     5341 ctcaagcaat ccttgaagcg gctgaagcaa aacaagcacc agtacttatc caaacatcaa
     5401 tgggtgcagc taaatacatg ggtggttaca aaatctgtaa agatttaatc actgatttag
     5461 ttgaagcaat gaacatcact gttccagttg ctatccactt agaccatggt gattacgaag
     5521 ctgctttgga atgtatcgaa ttaggctata cttcagtaat gttcgatggt tcacatctac
     5581 catttgaaga aaacttgaaa ttagctaaag acgttgttga aaaagcacat gcaaaaggta
     5641 tctcagttga atgtgaagtt ggttcaatcg gcggagaaga agacggaatc atcggtaacg
     5701 gcgaattagc tgatattgaa gaatgcaaac aaatggttgc tacaggtatc gactacttag
     5761 cttgcggtat cggtaacatc catggtcaat atccagaaaa ctggaaagga ttagcttttg
     5821 accacttaca agcaattgct gatgctgtag gtccagacat gcctttagta ttacatggcg
     5881 gatcaggtat tcctcaagat caaatcgaaa aagctatctc aatgggtatc tcaaaagtaa
     5941 atgttaacac tgaattccaa ttatcatttg ctgcagctac tcgtaaatat atcgaagctg
     6001 gtaaagataa agaaggtaaa ggattcgacc ctcgtaaatt attagctcca ggtaaagcag
     6061 caatcgttga agatgctaaa tctcatatcg actggttcgg ttcagctaac aaagcgtaag
     6121 catccacata acagatacga tatataggaa tggagaacga cttttgaagt cgctctccat
     6181 tcttttttac ttaaaacggc agaccatgct cgtttctttt ttttatctat gataaaatac
     6241 aagcatatcc atgaaaaaag attaataaac aaggtggaaa cagatgaaaa aaatcgtaat
     6301 caaaggaaac cgacctttag ctggtgaagt aacgatcagc ggtgcaaaaa atagtgcagt
     6361 cgcattgatt ccagctgcaa tcttagctga ttccccagtg atcttggaag gtgtgccgga
     6421 catacaagat gttcattcat taattgaaat tttagagatc atgggcgcaa ctgtccattt
     6481 ttccaacaac atactagaaa tcgatcctcg agaagtcgta tcgattccga tgccgcacgg
     6541 aaaaatcaat agtttgcgtg cttcttatta ttttatggga acactgcttg gtaaatttgg
     6601 cgaagcggta gtaggcctgc caggtggctg ttatttaggc cctagaccga ttgacctaca
     6661 cgtcaaagga tttgaagctc taggtgctga agtgacaaat gaacatggtg ccatgtattt
     6721 acggacagaa aataaaggat tgcgtggcaa tcggattttc atggacgtgg tttcagtcgg
     6781 agcaacgatc aatgtgatgt tagctgctgt aaaagcaaaa ggacagacag taattgaaaa
     6841 cgctgcacga gaaccggaaa tcatagatgt ggcaacttta ctgaataata tgggggcaaa
     6901 agttcgagga gcgggtacag atgtgatccg tatcgaagga gtcgaaacat tacatggctg
     6961 tcggcatttc atgattcctg accgcatcga agcaggaacc tatctagcat tagcagctgc
     7021 agtaggaaat ggtatcaaag tgaaaaatgt gatctttgaa catttggaaa gctttatagc
     7081 aaaattgcag gaaattggtg tccatatgaa aatcagcgaa gatgaaatcg aagtttaccc
     7141 ctcgaaagaa ttaaaacccg caaacatcat gacctatcct tatccaggat ttgccacaga
     7201 tctgcagcag ccacttactg cgttactatt gatgactaca ggcacttcag aaatcatcga
     7261 tacgatctat gcgaaacgtg tgaaccatgt gccggaacta gcacgaatgg gcgctgatat
     7321 taccgtggaa ggaaatatga tcatcgtgaa tggtccaaat aaacttcacg gcacagaagt
     7381 cgtggcttct gatcttcggg caggtgcttg tttagtgatt gctggactat tggcagaagg
     7441 gacaacgacg atttacaatg tagattatat cttacgcggt tatgatcata ttatcgagaa
     7501 actaacagcc ttaggggcat caattgaaat gatagaggaa gtgggagctg aatgagcgat
     7561 tatttgacaa tggcagaact agagaacaaa acgttaaaag aagtttatag ttatgccaaa
     7621 gaatttaaaa ttccttatta cagtaagatg aataaaaagg aattatctct agctgtgatt
     7681 cgtgcacaag cagagaaaca aggattttat tatatggaag gaatattgga tatcgttggt
     7741 caagatggtt acggtttttt acggccaatc aattatggac caagtgcaga agatatctat
     7801 atttctgcct cacaaatcag acgattcagt ttgagaaatg gggacaaagt ggcaggaaaa
     7861 gcccgtccac ctaaagaatc ggaacgttat tatggtttga tgcacgtgga aagcgttaat
     7921 ggaaaagatc cggaagaagc aaaagaacgt ccgcattttc cagccttaac acctctttat
     7981 ccgcaaagac agcttcaact ggaaacaaca ccgcaaagac tatctacccg aatgatcgat
     8041 atcttttctc caatcggttt tggtcagcgt ggattgatcg tcgcaccgcc aaaagcaggg
     8101 aaaacttctg tattaaaaga aatcgcaaat ggtatcaccg aaaactatcc ggaagtagaa
     8161 ttaatcgttc tactgattga tgaacgaccg gaagaagtaa cggatctaga acgaagcgtg
     8221 aaaggcgacg tggtatcttc tacatttgat ctgcagccgc aaaaccatac tcgagtttct
     8281 gaattagtat tggaacgcgc aatgcgttta gtcgaagata aacgagatgt cgttatcttg
     8341 atggatagta ttactagact tgctcgggcc tataacttag tcgttccacc aagcggacgt
     8401 acattgagtg gcgggattga cccagccgca ttgtataaac ctaagaaatt tttcggggca
     8461 gcaagaaaca tcgaagaagg tggcagtttg acgattttag cgaccgcttt agtcgataca
     8521 ggaagccgta tggatgacgt gatctatgaa gaattcaaag gaactggaaa tctagaatta
     8581 caactttcac gtgaattatc tgaacgtcgg atcttcccag ccatcgatat caaaaaatca
     8641 ggtacccgaa aagaagaatt attgatgcca agtgaagaat tagaagaaat ttggaaactt
     8701 cgaaaaaata tgactggaga ttcattagaa tatacggaac aactgatccg ctttttgcgt
     8761 aaaacaaaaa acaatcagca atttttcaaa gaatttcaag atgtctcctt tggtaaaaaa
     8821 aatccgacca gaaatctgaa aagataattg caaccttgac tgaaacatgt taagatgtta
     8881 atgttgtaaa tcgacaaatc aactctggtt cagcaaatgg agcagggcaa aggagcgaaa
     8941 aaatcatgaa agaaaacatc catccagatt accacccagt agtattcatg gattcaacaa
     9001 ctggtttcaa attcttgtca ggttcaacaa aaacttcaca agaaacagtt gaatgggaag
     9061 acggtaatac atacccagtc atccgtgtcg aagtaacttc tgactcacat ccattctaca
     9121 ctggacgtca aaaattcaca caagcagacg gacgtgtgga ccgtttcaac aaaaaatacg
     9181 gtctcaaaga cgcaaacgct gcggaataat aaaaacgctg ataactcaac gtttagcaga
     9241 ctatctgata gggatagtct gtttttttat gttttttgcc aatttaaaac ttcgtttgat
     9301 gctgaaaaag tcgtaggatc ataatgcaca aaacaatgaa aaactagtat atagttttaa
     9361 ttatccactt gataaaaaca ccttatatta acgaaatgaa gaggggttat ttcgaagtaa
     9421 aaaaccattt acctaaaatt agaagctaag ctttcctttc aaggaaggct ttttgttttg
     9481 ttatagactt gcgattgttt gtgagctaga tcgttcattt taatgactta tacacgcgga
     9541 tgatgggtct ttttcctctg ttcattcata atattgaacg gtacagctag cgatgctata
     9601 ctgacctcag ttccaagaaa acgttaacat tttttgtggg ggagaggttt tttatgaggt
     9661 ttgatcaatt gatcgcagaa gaactgattg ttttcgatcc atcgatagat tcaaaaggat
     9721 cattatttga gcgaataggg gatgtgttga aaaaaacaaa taaggtaaga aatgttcaaa
     9781 aagtcgttaa ggcactattc aaacgagagg aggagatctc cacaggaata gaagatggat
     9841 ttgggattcc ccatgcaaaa agcaaatatg tgacaaaacc agcactgtgt ttttttcata
     9901 cagccaaatt aacggactat agcgggatag atgaaatgcc aattgaatat atttttgcca
     9961 tcgtagttcc tgaaaaatca gcagatatgc atctagagat tctcagcaca ctctccagac
    10021 gattgatgaa tgcagatttt agaaagggaa taaaagaagc cactacgcca gcagatatca
    10081 tcagacagat tagtcaagaa tgaaaatagt agagtctttg tccgagtatc gatagtgaag
    10141 aaaaaggagg aaaataatca tgaaaatcgt tggtgtaact gcttgcccga ctggaattgc
    10201 tcatacttat atgtcggcag aaaaattaga agtaacagca agaaatctaa accatcaagc
    10261 aaaattcgaa acacaaggtg taaaaacaga aaatcagtta tctgaacaag aaatcaaaga
    10321 ggcagatgca atcattcttg cagtagataa agaaatcgaa ttggaccgat ttgccgggaa
    10381 aaaagtaaag cgtgtctcta caagccgagc aatcaaagaa ccgcaagtag taatagacga
    10441 agcattgaga gatattggcg tattcgttgt gtctaatgaa aaagaaccag ctgcaaatga
    10501 gaaaaagccg acaatctata atcatttcat gaatggtgtg aattacatgc ttccatttgt
    10561 gatcgcaggc ggaatcatca tcgcactgag ttttgccttt gggattacag cggctgatcc
    10621 caactcagca gactataatg tgttagcagc tgcattttca aggatcggag gagatacagc
    10681 gtttgccatg atggttcctg cgttaggcgc ggggattgct acatcgattg ctggaaaagc
    10741 aggttttgcc ccaggaattg ttgccggatt actggcctct acaggtggtt caggttttct
    10801 tggcggaatg attggtggcg tgctagcagg gtatatctgt gattttctgg caaataaaat
    10861 tagcgtaaaa aaagaatttt ctgctattta tcagctgatt gtcgtcccct ttttatcgat
    10921 cttaattatt gggcttttga tggtatttgt gattgaacaa ccgatcacat gggtgttgga
    10981 tgctttgaca aattggctga atagcttggg aaatacatcc gggctattgt tcggattact
    11041 tatcgggatc atgatggcag ctgatatggg tgggccgatc aataaatcga tttcgacttt
    11101 ctcgatcggt ttgatgtcag ctggagtaaa tgcaccgatt gctgcttgta tggctgcagg
    11161 aatgacacct cccctaggta ttgctttagc cactttatta ttcaaacata aatttaccaa
    11221 agaagaacgg acttcaggtc aatcatgctg gattttaggc gcttcgtata ttacagaagg
    11281 tgctataccg tttgcggtat ctgacccgat ccgcgtgata cctagtttga tgacaggttc
    11341 agcagtcgct gcagggattt ccatggcagt aggagttact tcaatggcac ctcatggagg
    11401 gatttgggtg atgctaattc caaatgttat gaacaattta cctatgtatg tcttggcaat
    11461 tgcatcaggt acagtcacta cagcctttat gcttggacta ttgaaaaaaa cagtgaaaga
    11521 gaaaaaacaa gacaagtgga cgaaaaatga aaatctaaca aatgaggtgg aagcgtaatg
    11581 ttatatacaa tgaaagagtt attgaaagtg gctaaagaga atcaatttgc agtaccagcc
    11641 ttcaatattt gcagctatga tatgatgaaa gcaatcatcg aagaagcaga gagattagaa
    11701 gcaccagtaa tcttagaaat tcatcctgat gaaatcgcct atttaagtga tgagtttgtt
    11761 gcggcagtaa gagcctatgc ttatacaagt aaactgccga tcgttatcca cttggatcat
    11821 ggcggtacga tagaagatgt cttacgggcg attcgaaacg gctattcttc cgtgatgatc
    11881 gatgcgtctt tgaaatcatt cgacgacaat gtacagatta cgaaaaaagt ggttgcgtta
    11941 gctcatgcgg taaatgtctc agtggaggct gagcttggaa cgattgggaa taatggttct
    12001 gctgaaggag gtgctgaaac aatcatttat acagatcctg atcaagcgaa gatttttgtg
    12061 aaagaaacag gaatcgatac acttgctgta gcaattggaa cagcgcatgg cttgtatccg
    12121 aaaaacagaa ctccaaaatt aaatatcgac ttactgaaag aattgaacca acaaatcgat
    12181 cttccatttg ttttacatgg cggttcaggt aatccggacg cagaagtcag cgaagcagta
    12241 aaatacggag ttgccaaagt gaatttgagc tcagatctta aaagcgtctt tttcaatgct
    12301 ttgagagaaa tattgagtga aaatccatcg atgtacgagc cgaatgcaat ttatccagca
    12361 gctaataaaa aggtacaaga agtagtcaaa cataaaatgg aaattttgaa cacagtaggc
    12421 aaggctagtt tatactaaaa ataaaaatgt gtggtcaaga gggtatgaca atagtcttgt
    12481 cataccctct taaccacaca cgatgttcag aagtagtttt ttcgaaaaat ttcttcttat
    12541 ttctcgaagc caatcacttc tgtcacaacc tcttttttcc tgttactata taaagtaaat
    12601 ggggtgattt tatgttgaat gaagtggaga atagacagca ggagattgtg aattatctaa
    12661 aaaacaacca atttgcaaga gtcaccgatt tgatcgagtt agtaaattat agcgaagcca
    12721 cgattaaacg tgaccttgtt tttctggaaa aaagtggatt gatccgtaga gttcgcggtg
    12781 gcgccatgct tattgacaat cgaaaaattg acgtgcctta cctgatgaag atcaccaaat
    12841 tagaagaaga aacagaaaaa cgtaagattg cagatacagc ttcttctttg attcgagatg
    12901 atatggtctt attcttggat tccagtacaa cctctttaca cttagtcaga aacctagcaa
    12961 gatttgatgg tttgcagatc attacgaatg gcatcgtcac agctgctatg ttgagtgaat
    13021 atacaacggc aaaagtatct gtattgggag gggcaattgt tccgaaacga gcaacaatca
    13081 acggttcaaa agcctataac gatgcattgt catattatgc ggatttagcg ataatgagtt
    13141 gtcgcgggct agatttcagc caaggagtaa cagaaactca tgaaggagag gcaatggtca
    13201 aaaaagcttt tagaaaacaa tcagaccggc ttgccgtttt agttacacag caaaaaattg
    13261 cacataaatt catgcatcaa gccattgctt ttcatgaaat cgattatctg gtgacaagta
    13321 aagaactgac aaaagaacag tatgcgaaag taaaggaaca ccatatcgaa tgtctgtacg
    13381 gataaattat tacgtgaatg ttctaagtgg cttcctcatt tttagatagg accttatctt
    13441 tgctcgcttc tctcagccga tggtataata atgaaaaggt tatcttgtta gataatctta
    13501 cttttttatc caggagaaag gagtgcagaa aatgaaacat gtgaaggcgt tggtagtgaa
    13561 ggcaatcatg atctgggcga ttctgtgggt cgtgctgaca ggtttatacg gtgttagctt
    13621 tatggattca acgattgttg gggtaattat tgtagtcatg atctatgtgc taggggatct
    13681 gttgatctta cgtaaagtag ggaacatcgc agcgacgatc gcagatgctg gttcagctgc
    13741 agttatcttg tggctctatc tatattttat gaatgataca gtcgatattt ggatgaaagt
    13801 attgattcct gctctattga tcggtgtggc agaatggttc ttccacaagt ggttgctaag
    13861 tcaaggcatc gtaccagatg aacggaaaat ggaataaatc aacagttaaa ctattcttat
    13921 cgataaatga aagctttaaa aataaataga tgtttaatta agaataatca taaactattt
    13981 ttactcaaaa aaccgctcag attattttca gatctgaacg gtttttttta tctattcatc
    14041 aagatcaaat ttcatttttc aatgattcaa tcaattcgcc ctctgcttca tgactatgtt
    14101 ttcggccatt aacaagatag agtgctgtac atatcaatgg aatgactccg gcaatcacat
    14161 acaatcctct aaatgaagta agagatttta gcatccccat caaataagga ccaacgccta
    14221 agcctaggtc taaaccaata aagtaggtag ataaagcaat actgattcga tgttcgcgga
    14281 cgatttttaa acaaacagcc tgtccatttg acataaacgt accataacct aggccgacta
    14341 atgctccaga gataagcaat gtcacactat tcgtcgttac actcagtaaa aataatcctg
    14401 ctgttaagaa taaatagcta ggatacatca cgtattgttc tcctttgaca tcgaaaatcc
    14461 ttccagtcaa tggacgtgta aatgtgatga ccaaagcata tacgacgaag aaaaatgacc
    14521 cagcagcaac taagtggatt acttttgtat aagaagataa aaatgataaa acacttgaat
    14581 aagaaagacc catcaaaaag gcaattcctg taatgaaaag tgctttcttt tcaataaaac
    14641 tattgatatt ccatgagcga agagatattt tttgttcttc agataatgga atatttttta
    14701 caggaaagac aaggcaggca atcgtaacaa agaagaccag tacaattgaa aaccagataa
    14761 tgaaacgaaa atcagtcata ttcagcaaaa tcattcctaa aaatggccca acagcggcag
    14821 ctaaactagt acttaatcca taataattga tgccttcccc ttttttagat gcagggatat
    14881 atgcagtaac gatagcattt gtagctgtag aaactgtacc gtagccgaat ccattcaaga
    14941 atcgaactaa atacaatgcc ccgatagttg gcgtataaag atatgctaat gttgaaagga
    15001 gatagaagat cgcgccgcct cttaaggtaa acttccgacc aaatagttct aactgtttcc
    15061 ccatgaataa gcgtgccagc aatgttccga tgatatagat cccagaagca aaacctgctt
    15121 ggctcaagct ggcgtgtaag gtgtcttgcg caatgactgc catgatgacc atcaacagat
    15181 aataaatcag gtagacaata aaattgatca atgtgattcc aataaaatat ttattaaata
    15241 atttcttttc catgtatgtt atacattccc cttaagctga atatgctttt aatttttgta
    15301 tttgaacttc tacatcgtga taattggatg gatagcgatc aacaagttgg cgaataaata
    15361 aatctcttgt agacataaac agatttaaaa attcttcgca ttcgtttgtt ggattctcat
    15421 ccactgcttt gatcaattcg atcgagtttt gatacgcatc atttaaaaag actaaagaag
    15481 ctttcatatc aaatcttgtt tgatatgctg tttctaatcg attaatgatt gtgttcatcc
    15541 agtaattcat gttttttccc tctattctta aaaaatttta cttctgcagt ataacgaata
    15601 aaaaaaagga aaaaaatcgc ataagtgatg gaaaaaggta cttaacaaat gttaatatca
    15661 ttagtaaaat acctttggac tttaaaaagt tttaaagtac tgtatgatct ttttagatga
    15721 aagtttggat gggggagcat cattggatag tagagtctta aaggaatatt tggataaaaa
    15781 tgattttccg attatacgca aaggatatca taaatatttg acattcgaag ggatggaaga
    15841 ttcccatacg tatatcttga aagagggaac ggtaaaagca agtgttattt caaatgatgg
    15901 gagagaattt aaccttcgct atatcaaaga tcttgaaatc gtctctcttt taaaagacga
    15961 atattcacaa ttcatcgatt cgccgtataa tattcgagtt gaatcagaat atgcagagtt
    16021 ttatcgaatc aatcgtgtgc gcttttggca aaatatcaac caagacccaa agctacaaca
    16081 ctatgtaaaa gagtattacc gctatcgtct gctttattcg atgaaaaaaa tgcagcaaat
    16141 gctattaaac ggaaagctgg gagctgtttg tacgcaactt tacgaattat atgatttatt
    16201 cggtgtgcgg acagaagaag ggatgctgat cgatttttcg atcacgaatg aagaaatcgc
    16261 caaattttgt ggcatctcaa ctgctagcag tgtaaacaga attttaaaac aactgaaaaa
    16321 agatggtatt atcaccgtta aagaccatca tatcgttatt ttgaatatgg acttgttaga
    16381 agacaatatt atcttttgat gaacaaagag gttgtgaaat cagcgttttg acctgagtat
    16441 tagagaaaca aacggaaaaa tagttcctca tattttgccg ttttttgagc taataccgag
    16501 ggtcagctga ttgaacaccg tttaccaaga ggttgtgagc ctgccgttta actctgagtc
    16561 acaaggaaca atttcaaaaa acagcttttc atgtttgatg aatattgtga cttgtgaccg
    16621 aggagttggt aggagaacac cgtttaccaa gaggttgtga aaaagctgtt ctgcatcaag
    16681 taataagaag agccaagtaa aaacagtctc ttatgttttt aacttggctg gacttatcac
    16741 cgtagatgta agcttttgaa cgccgtttat ttgcaacaaa aggggctgtg acacgatttt
    16801 tgtcacagcc ctttttttgc gaacattcat ttagcaattt ttagaaactt ctgccgccac
    16861 cgccaaaagt cccgccaccg ctagaatggg tagtacttcc gccaccgccg cttccaggag
    16921 gtgggctttt ggggattctt cttgtcgtga caaaagaatt tgtcagacga tcggtttttt
    16981 cagttaattt gatactggat ttttctcgga atggatattt gtagatgcct gatttcaatt
    17041 gataacgcga aacagtcaca aaataaaaga caagactaag gataagagcc aaaacaacag
    17101 caatgatgat ttctactgtc gtcaaaacct tatagcgtgt aattttgcca gtttcttcgt
    17161 ctacacgata atgtcctcct ggaactccgt cttccacata tgttgctgat ttagacaggt
    17221 aagcttttgc agcattgtaa taggcagcat ttgtcatctg atcataaaca tcatctaaga
    17281 tcgaatcgat tctgctatca gtcaaataat cgatcatatt accagaagtc gaaatgtaga
    17341 tttcacgctg tcccatatct aatagcaata ctgagccatt ttgatcattt ccgactgcgt
    17401 ctcttaagta attatcagca aagtctcttg gttcttctga attagatgta gtcgttacga
    17461 tcaagactcg tcctttgatt ttttcattca gcttttctgc ctgttgttcc aaagattgga
    17521 tttgatctgt tgtgaataac ccagcctcat catttaccgt agctgtatct gcatgagtag
    17581 ccaccggcca gccaacactt actagcaaaa gaaagaataa aaaaaatttt ttcatcatat
    17641 caagtaacct ccgatcagaa agaggatcgc tagcccagcg aaaatcccaa gagcggtcag
    17701 tcccaatttt ttctggctga tcggcaggac accgctgacc tttcctgttt gtccattcat
    17761 tgcgtagtag tagacttttt tacttgagtc attgcttcga taagtaacaa gccataccgg
    17821 cagtaatacg taattattta cttcgtttgt gattgaagca gaagttcgca caccggtcaa
    17881 tgttgtatat ccatttgcgg tatcttttaa cagcttctct gaatagtctt ttaattcaga
    17941 ttgaatctgt gatttgattg cctcatattc gatatctctt ttttctgctt ggaacccggc
    18001 taaatactgg cttttaaaat caattgcttt atctaacggg aaaggttgca cgccttcgac
    18061 catcttttgt tgcgtatttt ttgataaggc attttttact agttctttaa aagaaagctt
    18121 gcctgctctt gaaacagcaa attgcttcgt ttctgtgtat tcgatgtcac ctatccgcca
    18181 tatgcggata actgtaccat tcgcctgcat ggcaccatct acttcagcat ctgtagccca
    18241 ataagggaaa tacacacctg tcaacttatc gatttgatcc ttattgaaaa aagctttggg
    18301 aacaaaccat tttttcttgg tccaagcgag aaatctgttg attgcttctt ctttctcgac
    18361 agcaaaagga agtactttat ttggcaagaa ttctccgctt aaacgtcccg atagtacgac
    18421 gggattatgg cagtagtaac aataagtcgc agcagttgtc gcatcagtca cgatctctgc
    18481 accacagttg ggacaaagaa aaagatctat cgctgcggta ttatctgcag attcgtccgc
    18541 tgtatctgaa aaaccgcctg cctcgtcaac cgctttgcgc tcggcttcat tcatatcggc
    18601 aagctgttct tgggctgtaa aagtaaaatc ttcggtaggt gaaggttctt ctttgctttc
    18661 ttcgccagcc atacgcgctt ctttttgctt ttgctcatat tggctgactt cttcttctgt
    18721 atagatattc aggcagtatt cgcaatgaaa tttttggtct ttgggatcaa aagtcaacgg
    18781 accgccgcaa ttaggacatt tatgtgtaag aacatccatc agctgcacac ctttctaaat
    18841 aaattaatta acggggattc ctttaaacgg tttaccacag tttggacaga atttagggat
    18901 gccgttggaa agatccacga tctcattgca ttcactgcat cgcatttgta gcttaggctg
    18961 aacgttttct acaggtttgg cagctccgca gttggaacag aattttccgg aattttctgt
    19021 cccgcaaact ggacatgtcc aagtatccgc atttccttgt gcagtttgtt gattttgttt
    19081 ttctgcttgt tgtttgattt gttcttggtt attttgagct gcttgagaaa gataagaacc
    19141 atttgcattc attcccatac ctacacccat aaagccggtc attgctcctg cttcattttt
    19201 tccggctgct tccataccac gtgcaatgga accttgcacg tatccttcac gtacgctagg
    19261 atcacctagc atcgcccctt cgttacgcat attgatcagt ttcacagaat catcggtgta
    19321 agaaatgctg gctacagcca cagaaacaat ctccatccca cgtaattcac gccaagaatc
    19381 atccaatgca gtatccatgt atttgcttaa ttccaaactc ttagatggta cataagaaat
    19441 ccgttgacca tctgcagaca tctgattgat tgctgattgt agcgctgtta ggaattcagc
    19501 taaatactgc tcattgatat cattgatttc cacttgtgtt ttgtttttag ggattgcgtt
    19561 tgtataaaat aaaatcgggt caacgacatg aatagaataa gtgccatgtg cccgtaagaa
    19621 taattctgcg ttatagaaat tgtcaaagta gttcaacggc gcgcttgtac cgaatttgat
    19681 tccctttatt tcttggagat tgatataaaa aacttgttgt ttctgcggtg tgacgccgcc
    19741 aaatttgaat cggtcaaaag tttcagcaat tgcttctttc agtgttccat tgaacatgga
    19801 aggagctgcg tcatttttaa tggtgtaata accttcctca gcggtataat cgatgatttt
    19861 tccaccatcg accaaaagca tcatcatgtt tggatagaca tggacgactg ttccgtctgt
    19921 taaaacatct tctgttcctt tacgattgga gccacgtttg tcatctttgc ggactttgac
    19981 accttttgtc atgaccgttg tatcactcat attgtctggt tcgatgactt ctagccattg
    20041 atctgccaga ccgccgccaa ccatacttgt tgctgctttg ataagaccca taaaaaattc
    20101 ctcctctgat tcagctagtg ccaaacaatt attgtttatt tattatacca taggaagatg
    20161 tgaaacttct cggactagag acggaattga aatggaaaat tgcgtattgt ttaaatacct
    20221 gaaaaagccg agaaggatag tagttttttt acctaatatc acgtataata agagatagtg
    20281 aattttttaa aaaaggggga tccttatggc atatcaagca ctttatcgag tctggcgttc
    20341 gcagcgtttc gaagacatcg ttggacaaaa agctgtgaca cagacactaa aaaatgctat
    20401 tgtttcccac aaaacctcac atgcctactt gtttacagga cccagaggaa ccggaaagac
    20461 gagtgcagca aagattttcg caaaagcaat caactgtccg aacagtaaag acggtgagcc
    20521 atgcaacgaa tgcgaaatgt gtcgatcaat tactgctggt acgcaagaag atgtgatcga
    20581 aatcgatgct gccagcaata acggagtcga agaaatccga tttatccgtg atcgggcaaa
    20641 ttatgcgcct acaaaggcag cgtacaaagt gtacattatt gatgaggtac atatgctttc
    20701 aacaggagct ttcaatgcct tgttgaaaac attggaagag ccaaaagaaa gtgtcatatt
    20761 catcttagca acgaccgaac ctcacaaaat accagctacg atcatttcac ggactcagcg
    20821 atttgatttt aaacggatca atacggcaga tattgtcgaa catcttgaat ttatcttgaa
    20881 agaatcgact atcagctatg aaccagctgc attgaatgtg attgcccgtt ctgcagaagg
    20941 cgggatgcgg gatgcattga gtattcttga tcaggcaatc tcgtttagtg aaggaacaat
    21001 tactttagat gatgccatgc aagtgacagg tagcttaact gacgaaatga tggacagtta
    21061 cttgagtgct tgcgtgaaaa aagaagtacc agaagcattg gaaacattga accaaattct
    21121 cgcagccggc aaagaatcac gtcgctttct agaggatatg ttacaatact gccgtgactt
    21181 gctgatgtat cagcaagcac ctaacctagt tgaggaacaa tcgagtacga tcagaagtac
    21241 atttacagaa ttggcacaaa ctgtttcagc ggatcagctg ttttcaatga taaagatttt
    21301 gagcgatact caaaatgaaa ttcgttttac caatagtgcc gctatttatt tggaagtcgc
    21361 tacagtcaaa cttgcacagc taccgtctgc ttctgttcct tcagcagatg tagcatttgc
    21421 agatgatcag atagtaaaac agctacaaca agagattaag gaactaagaa acgaaatcaa
    21481 ggaactacgc agtaatacag gaattgagaa tacaaaagta cagccggtac agcaaacaaa
    21541 tcataaaaaa cagacaagta cctatcgtgt accgacggaa cgagtatata aagttctgcg
    21601 ggaagcgaca agacagcatc tgaaccaagt aaaagaagta tgggaagact tgctgatgag
    21661 tctatctgtc actcagcgag caatgcttaa agcaagcgaa ccagttgcag ctggacctac
    21721 aggactagtg attgcgtttg attatgagat tgtttgtcaa agagcagcaa atgacgaaga
    21781 attgcagctt tcggtacaca acaacttaag ccgaatgatc aaagattatg cgcctgatcc
    21841 tgtttatatt acaagagaaa gctggccaga acttcgaaga aattatttga cgcaggcaca
    21901 agaagaggga acagaaaact cttttgcttc tgaagactca gaaggagaaa tcgagttgct
    21961 tcctcaagaa caagaagtac cagaagaaac acttgtagta aaagcagagg aactgtttgg
    22021 ctccgaagct gttacagtgg tagatgatta ataaaaagga gtagataatt atgatgcgtg
    22081 gaatgggcaa tatgcaaggc atgatgaaac aagtacaaaa aatgcaaaaa gaaatggcag
    22141 aagcacaaga gctgctaaat aaaacagagt ttacaggtaa agccaccaat gaattggtca
    22201 aagcggtttt tacaggcgat cgtcgcatga aagatatcca aatcaatgaa gaagtcgttg
    22261 atcctgatga tatcgagatg cttcaggatc ttgtcgtaat ggcagtcaat gatgcgatcg
    22321 cacaaattga tgtggaaact gagaaaaaat tagggaaata cgcaaaaggt ttgccaggat
    22381 tttagtttta aactgaagga gtaatgaata tgcaatatcc agaaccaatt gcgaaactga
    22441 tcgacagcta catgaaactt ccaggaatcg gtcagaaaac agcgacaaga ctcgcctttt
    22501 atacgatcga tatgaaagat gaagtagtaa atgaatttgc taaatctttg ttaagtgtaa
    22561 aacgcgattt gcatttttgt agtatctgcg gaaacatcac agaagaagat ccctgcgaaa
    22621 tatgtagaaa tccttcacgt gatcgaagcg ttatcctagt ggtcgaagag ccgaaagatg
    22681 taatggcaat ggaaaaaatg cgagaatatc acggacttta tcatgttctc catggtgtgt
    22741 tatcaccgat ggaagggaca ggtccagaag acatcaatat ttcttctctg ttgcagcggc
    22801 tgcatgatgc agatgtaaaa gaagtgatta tcgcaacaaa tgcaacaaca gagggagaag
    22861 caacagctat gtatctctca cgtctgatca aacccgcagg tatcaaagtg actcgtctag
    22921 cacatggtct gtctgtaggc tctgatatcg agtatgcaga tgaagttact ttattgaaag
    22981 ctgtcgaagg aagacgtgag ttataaattt ctaattaagt gttttttcag atacaatata
    23041 aaagcagcac aagagatggg ggcaacaatg tgaacggact atttattaca atcgaggggc
    23101 ctgatggtgc aggaaaaacc agcatcttga atgaacttta ccctcttttg aaagaagtag
    23161 caaaaacaga aatcattcaa acaagagaac caggaggcat tccgattgct gaagagatcc
    23221 gagcagtgat ccttgatcca aaaaatgatc ggatggatga acgtacggaa gcactgcttt
    23281 atgcagcagc aagaagacaa catctagtcg aaaaggttct gcctgctctg gcaaaaggga
    23341 aaatcgtttt atgcgataga tttgtcgaca gttctcttgc ttatcaaggt gcaggccgac
    23401 gcatcggcgt taccgagatt gctcggttga atgagtttgc tacagaaggt actacgccgg
    23461 attttaccct ttatcttgac gtagattcag acaccggatt aagaagaatc aagaaaaaca
    23521 gacaaaatca aatcgaccgt ttagattcgg aaggtttgga attccaccag cgtgtacgtc
    23581 atgcttactt aaagctggca gaagagaatc cggaaagaat ccacaaagtt gatgcaagaa
    23641 aaagctttga agaagtgctg caaacaagtt atcatacaat tattgaacag tatccgcaat
    23701 tttttgaaaa ctaggaaggt gaacgtttat gaaaattatt ttagcgatta tccaagacaa
    23761 agacagcaac cgtttatcaa atgaattgat tgatgcaaat atccgtgcca caaaactatc
    23821 atcgacaggc ggcttcctta aggctggaaa cagtacgttt atcgtgggta ttgaagatga
    23881 ccgtgtagaa gaagcattgg aaatcatcaa aaaaacgtgt gaatcaagaa agcaatttgt
    23941 atctacacct gttacactgg atatttcgat ggatgggggc gtcccttatc cagtagaagt
    24001 agaagtaggc ggtgccacag tcttcgtctt acctgttgaa ggattccatc aattttagga
    24061 ggagctgagc tatgaatcaa gaaataaact tggctcaaat gcaaccgatc gtgtatcagc
    24121 agcttcaacg gagttttgag catgggcgta tcgctcatgc ttatcttttt gaaggggaga
    24181 aaggaacagg aaaacatgaa gtaggtatat ggcttgcaca gcacctgttc tgtacccaaa
    24241 tgaaagacaa tctgccttgt ggaaaatgca acaattgtca gcggatcgaa aagaaagaac
    24301 atccagatgt tttggttatt gaaccggaag gacaaaccat caaagtcgat cagatcagac
    24361 gtttgcagac ggaattcagt cgcagcggtt acgaatcaag aaaaaaagtt tttttgatca
    24421 aagaagctga aaaaatgaat agcagtgcgg caaacagttt gttgaaattc ttggaagagc
    24481 cccctggaga ttttttagcg gtgttagaaa cagatgcagt aggaagaatt ctccctacta
    24541 ttcaatctcg ttgtcaagtt ctgcattttc aagaactttc gaaagaagca ctgatccatc
    24601 gattgcaaga agagcagatt ccattggaaa aagcaaaact tttggctttc ttaacaaaca
    24661 gtttaggaaa agcagttgaa atctctcaag atgaatggtt taatgatgct aaggacttga
    24721 tttatcaatg gttcgtttac ttgcaaaagc aagatactca agcctttatc tatgtccaaa
    24781 aaaaattggt aaaatcattt aaagaaaaaa cacaacagtt tacaggatta tctgtcttga
    24841 tgttttatta tcaggaagca cagcgtcaag cagtagcaaa cggcgaatat ggcaaagtga
    24901 aacagataaa ccagataatt gaacggatat tgatcgcaga gcagaaacta cgcagcaatg
    24961 tcagttttca ggctgttgcg gaacagttcg ttttgcatac gattttttag cttgccgcaa
    25021 aggatgatga tcaaggagga tggaaatggt agaagtagta ggtgtccgat atagagatgc
    25081 aggtcatatc tattattttg caccaggaga ctctgaatat gtttatagtg acaaggtatt
    25141 agtcgaatct cagcaatcct tacatattgc tactgttgtc cttcctaaaa aagagattga
    25201 tcccaatgac cttcctgaag ctatccgtcc gatcttgcat aaagcgtcac aagctgaatt
    25261 agaaaaagac aaaaaaaaca aaaaagatgc ttatgatgca ttgaaaatcg caaaagaaaa
    25321 agtgcagttg cgtgagttgg aaatgaaaat ggtcaaagcc gaatacacat ttgatcgaaa
    25381 taaattgatt ttttctttca cagcggacgg gcgaattgac tttagagaat tggtaaaaga
    25441 tctggccgct gtatttcgta ctcgtattga gcttcgacaa attggtgtcc gcgatgaagc
    25501 aaagataata ggcggaattg gtccatgtgg gcgtccatta tgctgttctt cttttttagg
    25561 cgatttcgtg cctgtatcaa tcaaaatggc aaaagatcaa agtttatctt tgaatccaac
    25621 aaaaatttcc ggtttatgcg gacgcttgat gtgctgtctg caatatgaga gcgaagaata
    25681 cgagacagcg aaaaaagaac tccctgactt tggaaaagta attgctacac ctgatggtaa
    25741 agggaaagtc gtagggttga atctgcttag ccgtatcgtt agtattcggc tgactggacg
    25801 ggaaaatcct gtcgaatatg aatgggatga attgaaagaa tttatccaag taggtgagat
    25861 gaatggataa gagatcatta tacgacggat tgaatcaatt agaatcagag ttgagaaata
    25921 cattaacaga acttgttgaa atgaagcatg ctttgcatga gatcgtagaa aaaaatacaa
    25981 ctttggagat ggaaaatcaa cgtctgcggg aacacctgcg ggaattgaac caagttgcac
    26041 aagctccagc tgaaaatgtg aagcaggaac tttctaagtc tcgtatgaat cttgaaaaaa
    26101 tttatgaaga aggattccat gtctgctacg atttatatgg atcaagaagg gacaatgacg
    26161 agccttgtgc gttttgtcta gaagtgatct atcgcgaaag cggtcgatga ccaataacaa
    26221 gaggagactg gagcggagaa atactgctcc agtcttttta ttaaggagat tgtgacagat
    26281 gtataatcaa aaaagtttca agggaaatcc ggtatatggg gatttatatc ttgtaccgac
    26341 gccaattgga aatttagaag atatgagcta cagaagtgtt cgtatgctgc aagaatccga
    26401 tcttatcgca agtgaggata cgcgtaatac acaaaagtta ttgaatcatt ttgaaatcca
    26461 tacaccccaa aaaagtttac atgaacataa ttataaagaa cgtgtccctc aattgattgc
    26521 tttgttaaaa gaaggaaaaa cgattgctca agtcagtgac gcaggaatgc cttccatcag
    26581 cgatcctgga catgagctag ttttagcctg cataaaagaa gggatttctg tgatctctat
    26641 cccaggacct acagctggga tgacggcttt gattgcttca gggctagtgc ctcaaccatt
    26701 tttattttat ggcttccttc cacgtaagaa aaaagaacag aaagaaacat tgaaaaagct
    26761 aaaagaacag acagttacgc tgatttttta tgagtcacct tatcggatca ctgctacatt
    26821 gacgaatttc ttagaaattt ttggaaatcg ccaagtcgtt ttgtgtcggg aattgacaaa
    26881 ggtccatgaa gaatacctta gaggaagtac ggaagagcta ctcgcttata tcgaagaaca
    26941 tccagtaaag ggtgaatgtt gtctgcttgt agaagggaat ttgttcgaaa tgccagtgac
    27001 ggaagttgat gaagagttgg gaacgttaaa ggaacaagta gaagcaaaga tcgcttcagg
    27061 cgaaaaacca aatgctgcta tcaaagcagt agcgctgaaa aatgggctga aaaaacaaga
    27121 agtctaccgt cagtaccatg aattagactg agatagtata agttgtctat aatgaaagac
    27181 taatgaggaa atcagctact aacttttcaa atctcttgaa cgcgaacgaa tgttcttgta
    27241 taatgaataa gaggtgagga tgatggagct gcaatttcct ttacataatg atacatcaag
    27301 aaaaatcatt catattgata tggatgcttt tttcgcttcg gttgaagaac gagatcatcc
    27361 tgagtttcgc ggacatccat tagtaattgc cagacacccc agtgacactg gtgggcgtgg
    27421 agtagtgact acagcaaatt atgaagcaag aaaattcgga attcattcag caatgagtgc
    27481 acaaaaagcg tatgagcttt gtccgcaagc catctttaag cctggcgacc atcataaata
    27541 cagcgatatt tccaaacaag tacgggaagt attctatcgt tatacagata ttgtggaacc
    27601 agttagtatc gatgaagcgt atcttgatgt gaccgaaaat aaaatcaatt gcaagtcagc
    27661 catcaaaatc gcccgaatga tccaagcaga tatttgggag agtgtccagc taacatgttc
    27721 tgcgggagta agttacaata agtttttggc caaattagca tcagactatc aaaaacctag
    27781 aggaatcacg gtagttgccc ctcaagacgc tgtgccattt ttaaaagctt tgccaattga
    27841 aaaatttcat ggggtaggga agaaaactgt acctagaatg catgagctag ggatttatac
    27901 aggaaaagac ctatatgaat gcacagaaat gatgttgatt cgaaattttg gaaaaatggg
    27961 ctattctctt tatcgtaaag tcagaggaat ccatgattct ccagtaaacg ttacaagaga
    28021 gcgaaaatct gtgggaaaag agcatactta tgggcagccg ttgcaaacgg aagaagcagt
    28081 gctgactcag ttgcgccaac tagctgaaaa agtagaagaa gcactgagaa gagtccaaaa
    28141 acatgggaaa acagtagttt tgaaggtcag gtacacggac tattctactg tgaccaaaag
    28201 agtgacattg ccagaatata tctataaaaa agaagcactc ttttatcaag caagccttat
    28261 atgggaggaa atcttgggag tagaaaaagg aatccgattg ttagggatta ctttgacgaa
    28321 tctggacccg atgacttatg aaaacatcgt ccttccatta tgggaaaatc aagaaatata
    28381 aaaacagctt tgagagttga aaccggaaat ccgttttctc tcccaaagct gtttttatat
    28441 caagtcttgc tttttgattt gttcataggt ttctgttgca tccgtacatt tttcccaaat
    28501 cacaacttga ttggattcta aagatttttg gacgtcaatg atccgctggt tgctacttcc
    28561 gcgaaattgt agttttaggt cacgtttgct taattcaaag cgtccgtcaa caaggatatc
    28621 gatttgcgaa aggagttcta atttatcttc tgaatcttgt agcaattcat caaaggtata
    28681 gcctgtccat gaccagatat cttttgtcgt accgaactct tttcggatac gtcgtacgac
    28741 ttgcagacaa acatctgtat tcaaaaaagg ttcgccacca agtaaagtta atccttgcac
    28801 gtaatcgttg cgcaagtcag cgatgatttg ttcttctaat tcaggtgtga atggtttgcc
    28861 atatcggaaa ttttgtgcag ctttgttgaa gcagccttcg caggcaaata agcagccact
    28921 aacgtaaaga ctgttgcgga caccttcacc atcgacaaaa ttaaacggtt tgtagtcagc
    28981 aatatagttt tggctgtagt cttttgctaa ccattctttt ggttttggat ttctcataaa
    29041 aaaacttctt tcatttaagg ttcaaagata tagctattga agataaaatc tactcgacca
    29101 cataaataag aacaaactga cctaaatcca ttgttcaaga aagcttgttc ttattttgat
    29161 agagggcgtt caaagataca aagccatcga aagagggtgg tgaaaaaaga cttgtcatag
    29221 cctcttattc tgaataaacg gtgttcaaaa gcttgcatct gcagtaataa gcccaactaa
    29281 acgaaaaata tgaggaacta tttttgttta gctattctta ttacttgatg caggacagct
    29341 ttttcacaac ctcatttcat gtgtttcaca cgtgaggaaa tttctttatg gcggccatgt
    29401 accatcggac gagcttgcgg atttcctaaa tagccacaag tacgtttgac tacatcacat
    29461 gtttttggat catgatttcc acattctgga cattcgaacc ctcgttctgt cggtttgaaa
    29521 tcaccttcga aaccacattg atagcaatga tcgattggcg tattcgtacc aagatacccg
    29581 attttgtcat atgcaaaatc ccatacagct tctaaagctt tcggattttg ttggagcata
    29641 gggtattcac agtagtggat gaatccacct gaacaatatt ttggataatc cttctcaaat
    29701 tccaattttt caaatggcgt tgggttttta cgcacatcat agtggaaact gtttgtataa
    29761 tattctttat ctgtgatatt ttcgatgatg ccgaattttt ctgtatccaa acggcagaaa
    29821 cggtcagtta gactttcact tggagttgaa tagacactga aatgataacc atattcatcc
    29881 ccccatgcat ctgcattagc ttttaattct ttgacgatat caagtgtgaa agcttttgct
    29941 tctgggtttg tttcccattc gccaccgaag aaagctgaag caacttcata caatccaatg
    30001 tagcctaacg atacagtagc tcgacggttt ttgaataatt cattgacaga atcggtacgt
    30061 gaaagacgtt tcccgaaagc accatacata tataaaattg gcgcatttgc tggaatggct
    30121 tctttacaac gttctacacg atagagaagc gcatctttca tgatttctaa gcggtcagac
    30181 agtaactgcc agaatttatt ctgatctcct tttgattcga tcgcgattct tggcaaattc
    30241 aatgtaacaa cacctaaatt cattcgtccg acatttactt cttgaccatt ttcgtctttc
    30301 cacccttgca agaatgaacg acagcccata ggtactttga aacttccagt taattcaacg
    30361 attttatcgt aattcagaat atcaggatac attcttttcg ttgcacattc caatgctagt
    30421 tgtttgatgt cgtaattagg atcttcaggg tttaagttca cacctttttt caaagtgaag
    30481 atcagtttag ggaagatagc tgtccgcttt tcactcccta atccattgat tcgaatctgt
    30541 aaaattgctt tttgaatttc tctttcaaac cagttttctc ctagtccaaa tcctaatgaa
    30601 gtgaaaggag tttgtccatt tgaagtaaat aaggtattga tttcatattc caaactttgc
    30661 atagcatcga agatatcttt tttggttttt gcttttgcat attctttttg gcgttctggc
    30721 gaatcgatcc attcttccgc gtcttttaga tgttttttat agttcaattc tgcaaaagga
    30781 gcaagcaatt catctgttcg gtcggcagaa cagccaccat attgacttga cgctacattg
    30841 gcaataatct gtgagatttg tgctgtggcg gtctggatag attttggcga ttcgacttcg
    30901 gcattgccga ttttgaaccc attgttcagc atgcctttga aatcaatcaa gcagcaattc
    30961 gtcatcggtg tataaggatg ataatccaaa tcatggtaat ggatatcgcc tttttgatgc
    31021 gcatttgcta tatgtggtgg caacattttc agtccgattg attttccaac gatcccggct
    31081 gtcagatctc gctgtgtatt gaaaacatta ctgtctttat ttgcgttttc gttcacgaca
    31141 gtttggtcct tgttgattag cttttcaatc gaaaagttga tatctgttgc tttactgcga
    31201 gcaaaatctc gtttggtacg ataattgatg tactcttctg ctaattcata ttcgtttttt
    31261 tctagtaata tatgttccac gatgttttga atctcataga ttttgacatt ttcagcaaac
    31321 cggcttttga tttcttggac aaccaagtct gcaatcattt gaattttttc ataagtaagt
    31381 ggtgataatg agccgtgaat tttcttttct gctttgatca gtgcttcatt gatcttttgt
    31441 tcatcgaaat caacatggcg gccatcgcgt ttgatgactt tcatctggga tgtctctggc
    31501 tgctgagtaa cgacagtttt ttcttcataa tttactttca ttatcttcaa ctcctgctaa
    31561 attgttcttg tctatcataa aacaaaatcg gggaaggagc aactaaatat cggctatata
    31621 tagtattcaa tgtgctgtat aattggattt ctatactata tgtagtgtat attttattgt
    31681 gaaaaaaggt gaaaacttgt agctggtgga tttgtttttt gcatatttaa ttttgctgaa
    31741 taaaataatt gaataaaatt ttttattcag tccaagtaaa agtgacaaaa acataagagc
    31801 aaattattcg tagatatgct actatgcaaa taaatagaaa tgaaaaatga aagaggagga
    31861 gaagaattgg aaaagatgat cgaagtgaaa catctaagta aaagctacgg cagcaaactt
    31921 tctcccgtca aagccttaga taatatctca ttcacagtag aagaaggcga gtttgttggg
    31981 attatgggcc caagtggtgc aggaaagaca acgctgatga atatcttgtc cacgatcaat
    32041 ttgcctacga tgggcagtgt ctcgatccaa ggaaaagaaa tcacaaaaat gaaaaacagt
    32101 gagctcagtg actttcgtcg aaaaaaacta ggattcattt ttcaagagtt caatttgatc
    32161 gataccctaa atgcaaaaga caatatccta ttgcccctag cagttgaacg gatgactaaa
    32221 gaggaaatgg aaaagagagt aagacatgta gctcaattgt tgaatataga agaactgctc
    32281 aaacggtatc ccgatgaact ttctgtcgga cagagacaac gaattgcagc tgctagagca
    32341 cttgttgttc agccacaagt gatttttgca gatgaaccaa ctggctcttt ggactcgaag
    32401 tcggctacag aattgttgaa ctacttgaag accatgaatc aaaaagaaaa agcaacgata
    32461 ctgttagtca cccatgatcc atatacagca agctactgcg atagaatttt atttattaaa
    32521 gatggtgtga ttttttctga agttgtcaga agagggacaa gaagagagtt ctttgagaaa
    32581 gtaatagaca tgcaggcgac gattggcgga ggaggaaaaa tgaatgctgt ataaactagc
    32641 cgttaaaagt ttttttcggc agtcacgagg ctatcttgtt tattttttca gtttgacttt
    32701 atccgtaatg atctattatt ccttcagcgc aatgacctac gatcaatctt tagtcagaag
    32761 agcaagtcaa gatacttcga tagatggtgg attgagtttt ggtggattta tcattactgt
    32821 tgttttgctt tttttcgtat tcagtgccaa ccgatttttc ttgaatagaa ggcaaaagga
    32881 aataggcatc tatcagcttt ttggtatgaa taaactgcag atatcaggta tatatgtgtt
    32941 agaaatcatg ataattggat tgttcgcctg tatttctggg atattactcg gtattatttt
    33001 ttccaaactc ttttcaatga ttttggttcg aatgatggat atggatctta ctagtccatt
    33061 ttttatctcc attccatcag tagtagatac tttatttgct tttttcatca tccttttagc
    33121 agtatctgta tattcaatat ggaaaatatg gcgctatcca atgattcgaa gttttggaga
    33181 aaaagaacaa gcagatagtt caacaatgcg cttcaggaca aggcaccgat tactcgcagt
    33241 catcgggtta ctacttttaa cgagcggata ttttggagct agtcatttta gggaaatcac
    33301 ttcatggatg atcagttatc attatcttga tacattagtt ttcttttttc cttttttaat
    33361 ttttttcgtt tgtgtggtcg gtacttattt gtttttctgt tatacatttc ggttattttt
    33421 gatcatattg agtaaatgga agatttatta ctatggtatc aattttttga taatgggtaa
    33481 cacgcaagtt catttgctca aaagttggcg tacaaattct ctgattacag tcattctcgg
    33541 aatttcttta atgacaattg gcggcacggc tagtatctct actattttat cctaccagga
    33601 gaaagtttcc tccccgatgg actatcagtt tgatgttgag acagagaaaa aaatcaagcc
    33661 gattctagca gaggaagggc agaagataac taaagaaatc accttgcatt ataaagtcat
    33721 tgggagtatc tatagtcaaa atctcgaaga acctatgttt caaactgcta atctgatcac
    33781 ggaaacacaa tatcaagcct tcagaaaagt taatccagat ttgccgaaca tttctttgaa
    33841 atcacctggt catactgttt tgcttgatca aatgcaaact ctttttcgga atatttcatt
    33901 atatggatct agtattggac tgccagataa tcaagaattg aagattcaac aaatgcttcc
    33961 aagtgtatta ggtgacgaaa caatggtata tctaagtcct gtactgattg tagatgatac
    34021 cgtttttgaa aaagcaaaag gtgtggatta tcaagtagtc aatgtagatg tatcaggtgg
    34081 aaataatgaa aaaatagatg aacgactgag caatgacctg tcgataaagt ggctcaatgc
    34141 tgtttattat tcttatgata tcgtaaatgg aagtctacaa ggagaaatta gcacaaagaa
    34201 acttccggat gaccaaatga aggaagcaca atttagccaa gaaagctctc gtttgaattt
    34261 ctcttccagc tattcgaaat tgcgtgcagt taatcggcga atcggtatca atatttttgt
    34321 cacactattt gtcgggatga tcgtgattat tgctactggt agtattttga cagtccggca
    34381 attagcagaa gcagaggaag aaaaagaaaa ttatcaccta ttgactaagc tggggattcc
    34441 acaaagaagg atcagacgga tgatcttcga gcaaaacgca cttaccttct ttccacccat
    34501 gatattaggg atcactcacg cagtatttgc aatcaatgtc ttcactcagt atataaaaac
    34561 tgccgattac tggttggctt atcttgtgag tggcttattg atccttatct atcttttgct
    34621 ttatgtcatt acgagtcagt tatattgtcg gattatcgag gaatgatata cggaataaga
    34681 caagataata aatagaacta aattttgaat accatttatt tggaataaga ggttgtgaca
    34741 cgatttttgt cacaacctct ttatttttta tattttttaa aagtacgaga aattataaag
    34801 aaaaaagcag tgatttgatg tgctattttt ataaaagcta tgtgacaaaa ctgttagtaa
    34861 aaaaacggtt tctgtaagct agacacatgt ttctttttgt caaaattagt tacactttgt
    34921 gtgaggttat atgaggaggg aatccaatga acaaatggcg ttctaatcca aaattgaatt
    34981 attggggaaa attcatcatt cgaacaattt tttatagtgc agtactgctg ttcctgattt
    35041 atctgtatca ctataaaaat attcaaggag gaacttttat ctataacgaa ttttaggagg
    35101 aagagtatgg aaatcaaaac gattattgaa gcaatcgatg attggggaat aaatgaacct
    35161 gatcgagttg cttatcaggc ggatgagacg catacttttg gtgaattgaa acaagcatca
    35221 gacgcacttg cttattattt agaaaaaaag gtagaaggcg atggaccaat tgtcgttttt
    35281 ggcaatttgg agtttgaaat gattgtctca tttctagggg ttgtcaaatc tggccatgcc
    35341 tatttgccga ttgaagagca tacacccaag gagcgtatcc tatcgatctt tcgggtggct
    35401 aaaccatcta tggtcatcag tatcggggac tggatagaag atattccttc ggttcctgtc
    35461 ataacaaaaa aagaatttca agaaatcaag aagataccag taggatttta tcccagaaat
    35521 agcgtaaaag gtacagaaaa tttttatatt atttttactt ctggtactac tggagaacca
    35581 aaaggcgtac aaatcagtca tgataatcta gtcagctttg ttcaatggac gatggaagac
    35641 tttgggatca agcctggtat gcatttctta gcccaagcgc cattttcttt tgatttatcg
    35701 gtattttcta tttatcctgc attagtttct ggcggaatgc tgaagccgtt aaataaagca
    35761 gttgttcaag actttcgtca attattcgcg acattgccag ccttgaagtt gaatgtgtgg
    35821 gtttctactc catcatttat ggatatttgc ttgatggaac ctacattcaa tggagaaaat
    35881 gtgccggaat tggacatgtt tttattttgc ggagaagaat tgacgaaaaa aactgcagaa
    35941 agtctacttg atcgattccc aaatgcacgg atatataata cttacggtcc aacagaagca
    36001 actgtagcta tttcaagtat tcagattgac cagcatgtac tagatagtta tgaccgacta
    36061 ccgattggct acgtaaaaaa agacacgaaa gtttctattg tccaagaagg taaacctgtt
    36121 tcaaaaggag aaacgggtga aatcattatt gcaggaccaa gcgtatcaaa aggttacctg
    36181 aacaatcccg aaaagacagc tgctgcgttc ttttgtcaaa atgacttagc aagttaccat
    36241 acaggggatg caggtagact agatgaatat gggcttttat tttatgaagg acgtatggat
    36301 cagcaggtca aattacatgg ataccggatt gaactcgggg atatcgaaca ttatctgctc
    36361 caagacaacc gaatcaaaca agctgtcgtc gtaccaaaat accaaggaac aaaagtacag
    36421 cagctggttg cttttgtcgt attagaaaac aaaacgaaac agccggattt tcagttgact
    36481 aaatctatca aagaacaatt actagaagtt gtaatggatt atatgattcc tcagaagttc
    36541 cattatgtcg atctgctgcc tcagacagtt aatggaaaaa tcgatcgaaa aaaattaaca
    36601 gctgaggtga atcctgaatg atgttacctc atatgatccc ttatgcagag ccgttttatt
    36661 tttttctttt agccattgcg cttgtaccga tcgttctatc tttattgata tgggaaaaaa
    36721 gattaccagt ttatcaatca gcagtgacac ttttcttttt atttgtcagc tttggaggta
    36781 attattggca acagggagcg gcgctgattg ggtatgtttt gtggcagacg atacttgtat
    36841 ggggctattt tgtttatcgg caaaggaaaa atcagacagg atggtttttt gccgccgtta
    36901 ttttagcgat aattccactg tttttaacga aagtgactcc tttttttgaa catggaaaag
    36961 catcgttact tggtttttta ggaatctctt atttaacctt taaatctgta caaatgatca
    37021 tggaaataag agatggcatg atcaaaacat ataagccatt tcgttatatc cagtttctgc
    37081 tgttctttcc aacaatctct tctggaccaa tcgatcgcta taggagattt gaaaaagatc
    37141 agctccatcc gcctgttcgt gataaatatg ttgatctttt gggaaaaggc gtccaaaata
    37201 tttttgtcgg ttttttatat aaattcatta tcggttatta ttttggtcaa gtactgcttc
    37261 ctgtagtggg acgcattgcc ttacagcatg gtggtatttc atgggcatta gtaggttata
    37321 tgtacgtgta cagtatgtat ttgttttttg attttgctgg ctatagctta tttgcagtcg
    37381 gtacaagcta catgatggga tatcagacac caatcaattt caataaacct tttttatcat
    37441 ggaatatcaa agaattctgg aatcgttggc atatgacgct gtccttttgg ttccgtgatt
    37501 atgtatatat gcgattgatg ttcttcatga tgaagaaaaa attttttaaa agcaagatcg
    37561 taatgtcaaa tatcggttat tttgctttgt ttcttctaat gggtatatgg catggattga
    37621 cgtggtacta catcgtatat ggactgtatc atgcttgtct gatctgtctg acagatgcat
    37681 ggatccgatt taagaagaag cataaagagc agttgccttc taacaaattt acgcatggct
    37741 tagccgtatt tttgacattt caagcagtat gttttagctt cctgattttt tcaggatttt
    37801 tagataaact tttttttagc taacgaatag tgacatatta atttatataa caaaggagaa
    37861 aaggaaaatg gaagaacaaa ttttatcaat cttagaagaa ataacaggaa cagatgaagt
    37921 aagaaaaaat cgtgatattg atctatttga tgaagggttg cttgattctt tagcatctgt
    37981 tcaattatta gtcgagctag acggagagct ggatatccaa gtccctgtat ctgaattcga
    38041 gcgagaggat tggagcacac cgaataaaat cattcaacaa gcaactgcat tgaagggttg
    38101 agtatgaaaa agaaactttt tgctattttc ggcccggttg ttttagctgt tggcttactg
    38161 tttgtgtttt ttacctcctc ctatcaagta gatatctcta atccagaaac gattagacgt
    38221 gcctcttctt ccatgtcagt gaacgtgttg aaaggagatg cgataaaaaa ttatgcatta
    38281 tctgaaaaac aatatattcc tttttttggc tcaagtgaat taagcagaat cagtccattt
    38341 catccgtctg ttctggcaga aaaataccag cgaaactatc gtccattttt gctgggagca
    38401 cccgggacac aatcgttaag ccaatatatg atgatgcgtt ctgcaggaga tgctatgaaa
    38461 aacaagaaag tcgtctttat tatttctcct cagtggttcg ttaaaaatgg tgtaaaaact
    38521 gattacttta atacgtatta ttctgaactt caaacatacg actggttgtt ttcaatgaag
    38581 aaagtaacgc ctgctgatcg ctatttagct agaagattat taactttctc aaaagtaaaa
    38641 gagaatgata cgttgacggc gattctgcaa acgatcaaaa aagggaagct acctttacct
    38701 gaatctttga atcagctgcg cagccaatgg aacatgctga agagagagga tgaagtattc
    38761 agcaatattg ggttgaaaga tcgacagcaa aaaatcgatc atgagtcaaa acgattacca
    38821 aaacaatacc aagaaacaga attatccatt ttagcaaatc aaattggaga acgagaaacg
    38881 acgaataatc cattcgggtt gaaaaacgat ttttatacgc atcgtatccg agcccacgag
    38941 ccagagctca aacagtcaca aaaaaattgg gattatcgtt tttcgccaga attttctgat
    39001 tttcagctgg tcttggatca attagcaaaa aaccataacg aagtattgtt catcatccca
    39061 ccggttaacg agaaatggag cgattatacc ggactatctc aagaaatgtt acaaggattt
    39121 gccaaaaaga tcaaatttca attaaatagc caaggattca atcgaatagc tgattttgtc
    39181 aatcaagcgg gtaccaacta ttttatggaa gacacgatcc atctaggctg gaaaggctgg
    39241 ttggctgcag atcaacagat cagaccgttt ttagaagaaa atcatattac tgctagtaag
    39301 tatcatcttg acgatgcttt ttttagcaaa tcttggcaac atcaaatacc agataaacta
    39361 caattaaaat aaagaaaaca ggcgagtgtt gctcgcttgt tttctttatt tttgaatatt
    39421 ctgaataaaa gataaaaata ccaagtttgc ctgaacaaaa atcataagca atggtataat
    39481 cacaatatga atatagaaat gggggaaaac atttggatac aaaagaagaa cagctactta
    39541 ttgatttaac ttctgcaaaa ggagtacctg gaaatgaaga agaggtaaga gaagtattca
    39601 gagaatatgc caaaccattc gctgatgata ttttttatga cggtttaggc agtgtgattg
    39661 ccaaacatgg tgctggcgga ggccccaagg tctttatttc tggacatatg gacgaagttg
    39721 gttttatggt aacaaaaata accgaaaaag gattcttgga attccaaact cttggaggtt
    39781 ggtgggggca agtcatgctt gctcagcaag ttgaaatcaa aacacgtgaa gggaaaatcg
    39841 tccacggtgt gattggttcc aaaccaccac atgttttaac acctcaagta agaaataaac
    39901 cttatgaaat aaaggatatg ttcattgata ttggcgcatc aagccaagaa gaagccaaag
    39961 agtggggcat acgtcctgga gatatggtca ctccatatat tgaatacaaa cgaatgaatg
    40021 gcagtaaata tttactggca aaagcatggg ataatcgtat cgggacagct gtttctctgc
    40081 gagtattaga gaatctatct aaagaagcac acccaaatgt tttattcgca ggaagcgatg
    40141 tgcaagaaga agtaggcttg cgaggtgctc gaacaagtac acaccttgta aatcccgata
    40201 ttgcttttgc tttagatact ggtacagcag gagacactcc aggaatgaca ccaaaagaag
    40261 cagattcgat tttaggaaaa ggcccacaga ttttgatttt tgatgcatct atgatcccgc
    40321 ataaaaaatt attgaatttt gttattgatg tagcagagga aatggatatt ccattccaat
    40381 atacagtgat ttctggcgga ggaactgatg caggacaaat gcatttgaca agagatggtg
    40441 ttccgtctgt agccattacc gttcctgttc gttatctgca ttcccataca tcagtgattc
    40501 atgaagatga ttatttgaat acagtgaaac tagtcacaga attagtgaaa cggcttgata
    40561 gtgaaacagt tgaaaaaatt cggagttatg aataatgaat aatagaatac ctatttctga
    40621 atatcggaaa aaagcacgag tttctttgga aaatcaatgg ggaatcaata cttggcttgt
    40681 tttcttatct ataatattta cgagcgtcat ccagaacttt tttgacggtt tcagtccttt
    40741 tccggaagaa agcatgcagc agcacttatt gagttttcta gtcgataatt tacttttatt
    40801 cgcattcaac tatgcattgt tttacattgc gctagtagtt gtacggggtg gcagaccaaa
    40861 aagtaacctt ttattttcag ttttccaaag aaagtatttt ggttcgatac ttggcatcaa
    40921 tttgatcaat tcagtcatca actggctact caacagttta atctttctgc ccatgttttt
    40981 aatcagcgga gtgagtactt atatgcagct gcttttcagt tcaaatgcgg tacctacggg
    41041 tgtcatgcca gaagattttc ttgatatcag ctttgtttta tcgatgatag ggatgatttt
    41101 tgtttcagca ctcatcatga gtattgttgg cggtttattc caatttgctg catggacaaa
    41161 gttcgactat cctgatttgt cggttattca atgtttgaaa tatggctggt ttttattgaa
    41221 agatagaatt ggtacgtata ttttgttgca gctgtctttt atcggctggt atttgctagg
    41281 agcaatcgct ttgttcatcg gtcttttgtg ggtcattgtt tatgtgaatg tgtcagttgc
    41341 agaattttat gaacaagcac ggattgaaaa aggaggtcca gacgcctatt ttacttagca
    41401 tgtaagcagt ttattcatca aaaaaataac ttttgtggta ggataaatct ttgaggggga
    41461 atgtacgatg aaattaactg ttttaggatg cttaggagcg tatccttata aaaatcaagg
    41521 gacaacaggt tatttgcttc aatctgacgg gttcaatttg ttgatcgatg caggtagtgc
    41581 tacgctgatc aaattacaag aacaccttga tccacttgat ctagatgctg tgatccttag
    41641 ccattatcat catgatcata ttgctgacct tggtgtatta cagtattact ggcaacttca
    41701 tcctaagaga aatccggaga cattgctttc aatttatgga cacacaaaag attccattca
    41761 ctttgaagaa ttgacgttgg aaaatgtctc aaaaggacat ccttattttg aagctgaaga
    41821 attaaaaatt ggtccttttc tgattacttt tatggaaaca atccatccag tagtatgtta
    41881 cgccatgcgt atcgtagaag aaacaacggg gaaagtattc gtatttacag gtgattcagg
    41941 ttatttggaa agtttcgctg attttgcgaa agatgctgat ttgtttctag cagataccta
    42001 tctttttgaa ggaaatgaac atcatcatgc ccatttcact tcaaaagaag ctggagaact
    42061 tgcgaaatca gctaacgtaa agaaacttgt acttacacac ctacctcagt ttggtgattt
    42121 agaacaattg aaaaatgaag cgcaaaaggc agcaggcaaa gggattgata tagaacttgc
    42181 tgcagttgac aaagtgttta acatttagga ggaagaacat gatttttgta ccaaatgaaa
    42241 accacgaccc aagaatcaat ttagcaattg aacaatattt gctgcaagaa atgcctttag
    42301 atgaacctat tttgctcttt tatatcaatg aaccttcaat catcatcggc agaaaccaaa
    42361 atacgcttga agaaatcaat cgagattatg tggaagaaaa tggcattcat gttgtccgtc
    42421 gcttaagtgg aggcggagct gtctaccatg attttggaaa cctgaacttt agttttatca
    42481 tgcctgatga tggggattca ttccgtgact ttgcgaaagt aacacagcca atcatccaag
    42541 cacttcatga attgggtgtt gctggggcgg aattgaaagg ccgaaatgat ctagtcattg
    42601 atggcatgaa attttctggc aacgcgatgt atgctaccaa cggtcggatg tttgctcatg
    42661 gaacaattat gttcgactct gatatcaatg aagtagtcaa tgcattaaaa gtaaaaaaag
    42721 acaaaatcga atcaaaagga atcaaatcga tccgttctcg tgtaacgaat atcaaaccat
    42781 ttcttccaga agaaaagcaa aaaatgacaa cagaagaatt tcgtcaagaa atcttgttga
    42841 aaattttcgg cgtagagtca gtagaagaag taaaaacgta cgaattgact gatgaagatt
    42901 ggaaaaaaat caatcgaatc tctgaggaat attatcgaaa ttgggattgg aattacggga
    42961 agtctccaga tttcaatttc tctcgccaaa aacgtttttc tatcggttcg attgaagtcc
    43021 atttgaatgt ctcagaagga atgatcaaag aagcaaaaat ctttggcgat ttcttcggac
    43081 taggagatat ctctgacgtg gaaaaaaaat tggttggaca gaaatatgat aaagcatctc
    43141 tatcaaaaat agtcagccaa attgatgtga agaaatattt tggtgcgata gaaccagaag
    43201 aattgcttac cttactttat tgaaaataaa aaatagcgga atccacatat atggattccg
    43261 ctatttttta tacaggattc gggtaatttc gagagagttg aacagtgatc cgatcaatga
    43321 aagtatcttt ttcctgcgtt agtgttcctg tgtaacgatc cgctacgtct ttcatcatca
    43381 ttaagtcaaa acgttcctga tcatctaatt cttctgtgat gcctcgacta aataggtttg
    43441 tatcgtaatg tgcactatgt tcgcaacaaa tgacgaaatg ttcctcttgt tcgtgtatcg
    43501 acaaataaat ttttcgatac agtggatttt cgatggcatg agtttctcta aaggaatgct
    43561 ctaaagcgtg gatcaaaagt tgagccagat cgtcatcgtt gataggaagt tcttcgggaa
    43621 gatctgcttg gaaggttatc tgaatattcc gtttggcagc taacttctgg taacgcgcta
    43681 agataagatt tgtcacctgg tggttgcaaa aagaacacag catttcgaaa ttttttgctt
    43741 cttctaatat cttttccaca tagtttttag cttttgtttg gtccgtatgc attaaatctt
    43801 gcagattctc catctcttgg acaaattcca ggcgaagtgt atttacttct tggatatgct
    43861 gtcgaagctg ctcataatgt tgctccaaca aatcattttt gatttttaag aaatctactt
    43921 gtctccgatc tttgtcggta tttaagatgt gatcgattag attgtagctg ataataacga
    43981 ttagaatgat aatatataaa atcgtagacc aattgatcgt tgtttgatag atacctaatg
    44041 ccgtttggat gtaaatcaag caatggataa tggctaccaa gacgatccaa ggtgtacaag
    44101 ctacataaaa acggttattc ttatatgctt cgccaatgca tgcaagtgaa gtgactaaag
    44161 tgcttataac actagcaata ttagcaatcg gcattaattc aggaagttct gcaggagtaa
    44221 aagttgcata aagcagaacg ccgataaaaa tcaaaagttg gaacgtacaa aaaattccgt
    44281 accatttttt atagtaaaac attcggctcc aatagtagca gatgatgaaa gctgacgtta
    44341 agataataaa taaatgagat aaaaaagaat gaacgaatgg ttcaaaaaga ataccactta
    44401 aaatatcttc tgatacagct tcaaatccta atgccaaagc aaagcaactt aagagaataa
    44461 gtgagtattc aagacgtttt tgtttataca tcaagtagat cgtatagaaa aaggtcccta
    44521 tagcgataaa aacagcgatt atcatcgtca atacttgcgg cactgattgt gaataaataa
    44581 aactaatcaa tggtccagtt gttcctagat aaactttcgg tggcagtcca gcatagttct
    44641 gataaggaga tgagactgta agggtcaatt tttttccgat ataatttgct ggtaaatcta
    44701 tcacagccaa tgagagtccg ggattgcttt cttcctgata atctttccgt tggtataaaa
    44761 tcttttcgcc tagatataca gtaatccatt gatggtttcc tttgattagt aaatttgctt
    44821 cgtccaacgg tttttcaagt gtcgtttcca taatgaatgt ttcgtcttta tccacggtag
    44881 gaatcgtacg agtgtacttg ctgtcaaact taaaatcagg atcatctttt gtatagaaaa
    44941 cccacgaatc ttttatttct ttcatttgat tgctgtccgc aggagaaaaa ataaaataaa
    45001 agaaataagc aattcctgtt aaaaataaca atgataatat aatgattatg ctccacttta
    45061 tacgtaaata aaaagattct tttttattat atatgttatt aaaaaaagac ataaaggtat
    45121 tcctttctaa aacttgtaat gttagggtaa acgtttttta aactaacgtc aattatttat
    45181 aataaaaaat gagataaaga tgaggaaata gaattagaaa catataatta ttaaagggaa
    45241 acatttttac agctataatt tgaaaaaaat ttatcgttat tatatgatta agaaggattg
    45301 aataaagaaa gaagttgaaa acgatacctg attacaaaaa aataactttt ataagttcta
    45361 taacgttgat tatattttta attcttattc ttctcgtcgt cttggttccc cgaatttttg
    45421 gtttgactcc ttatattatt gaggacaaag aaatgagtcc atattatgca caaggaaatc
    45481 tgatatatgt acgaccgaaa aatacaaatg agattttagt cggagatatt attacatatt
    45541 atgaaaattc aggaaaaaaa atctcgacgc gtcgcgtaat agccgttgaa aacaaccacg
    45601 aagattttta tacaaaagct gatacaaaga cttatattga gcctggagta gtaaaaaaga
    45661 gaaatattat cggtagtccc atctttcaga ttccatatat tggactagtc ctttcaaaaa
    45721 cggcatttgc atggattcag gggttattct ttacgattgc tttttgccta acaggaatca
    45781 cagcatggaa tacctttgta gagttgaaaa agaagcggag acgaacacag aaatttttgt
    45841 aagaatgtta aaaacataaa tgtattccag agatccaacg actcttctga acatgaaaca
    45901 cgagaaaaca ctcatgcagc ttgtagattt agtcagttgt tcgtataatg tgtgaagagg
    45961 aggagtagta tgcgcaatga aatgatgcat cgtcctgtag tcaaagaaga actattggat
    46021 tttatgcgta cccagcaaaa aaaattaccg ggtgagctag gcaaactgga agaagaagct
    46081 catgtagcag aagtaccagt tattccccat gaaacagttg tatttttgaa atttttactt
    46141 ggacagcttc agcctgaacg aatcttggag atcggagcag ctatcggttt ttcatcaagt
    46201 gtcatggcca cgacaatcgg agaaaacgct catgttacga caattgatcg tttcgatgtc
    46261 atgatcgaga aagctaaaaa aaactatgaa cgtctaggac tgacagataa agtgactttg
    46321 cttgaaggtc aagcagcaga tatcttgccg gagttgtctg gtccgtatga ctttattttt
    46381 atggatagtg caaaatcaaa atatattgaa tttttacctg aatgcttacg tttgttaaga
    46441 aaaggtggcg ttttgatggt agatgacatc ttccaaggag gaacgatctt gctcccagat
    46501 gaagagattc cccgtggcaa acgagctatc catcgtaaat taaatgaatt tcttcgtgtt
    46561 gtgatggatc atcccgattt gacatcgaca atcttgccat taggtgatgg tgtgatctta
    46621 atgacaaagg aatcagaaac aatcgagttg tgatacatga ttatggcagc ctgtagataa
    46681 tcgattgaat cgagggctca attcgaactt gatgtaaaag tttctatatt tgtaagtcaa
    46741 ttaaaggata caggaaatct aaataaacag gagtagcatg aagtcaatgt agctcctgtt
    46801 ttcaattgat aaccttagaa cagctgaagg agaatgtctc gttttaaaag attgatttag
    46861 tagttgggcc aaaataattc attatttgct aattaaataa ctatttcgta ttgacagaag
    46921 caatttaatt atctataatt attgatgttc cgctgattct tgtcatagta gctcagctgg
    46981 atagagcatc cgccttctaa gcggacggtc gggggttcga atccctcctg tgacgctaaa
    47041 aaaccgttag aaactgaggt ttctaacggt ttttctttgt tttttgtgcc aatattgttt
    47101 gttttcaaag gcaaataaaa taaaaaaaca tccttatcga gtacaattat aaggagcaaa
    47161 aaaataaaac tcatcagaaa agaggaagaa gatatgacga tactatctag aattttagtg
    47221 actctagttg caattgaatt tttttatatc atgtatatcg aaacggtgag aactgattct
    47281 gacacgacaa gtagggtttt taaaatgagt aaagaagagt taagcagaaa atctgttcaa
    47341 acattgttta agaaccaagg agtgtacaat ggactattag gagtgggact actttatgga
    47401 gcttatcttt cttccgcatc taaagaaatc acaagtatgc tattaatatc tatttttttt
    47461 gttgcattat atggcagttt gactagcgat cgttggattt tactcaaaca aggtgggcta
    47521 gctctgttgg cattgctttc tattttctta taaatataga aaaaataaga atttatctaa
    47581 caggaaactt tgtgaaaaat attactttat ctcatgaaat atgatattct aatgaatggt
    47641 attttagaaa atttcatgaa aaaggagtta gataggtgtt caaaaattat gtttcctcac
    47701 taaaaaaaga attttcaggt tatgatcttt caagatttca gaaagatctt ttggctggga
    47761 tcacagtagc tgctgtagca ttgcctttag ccttggcttt tggggtatca agcggagctg
    47821 atgcggccgc aggtttgatt acggctatca ttgccggtat cgttattggc ggtttatcag
    47881 gcggttttta tcaaatatca ggtccgacag gtgcgatggc agctatcttg atgtctattg
    47941 cggcaacaaa gggaatgcaa ggtgtattgc ttgctacttt tttagcgggt ctatttttac
    48001 ttgcagcagg acttttccga ttaggaacac tgacttcttt tatcccagca cccgtaatta
    48061 cggggtttac ttcaggtatt gctatcatta ttgcattagg tcagatcgat aatttatttg
    48121 gtgttcactc ggaaggtaca aacgttattg aaaaactaag tagttatcaa acgataggat
    48181 ttccgataaa cacagcctct ttgatcatgg gagggctagt cattttaggg atgtttatct
    48241 atccaaaaaa atgggcgaaa cgaatgccta gttcgctgct ggctatcatt ttggcaacag
    48301 cagttatgct attgttccat ttaccagtag caactgtggg taagattcca caaacattga
    48361 tcagtagtaa tcgtttgaat atgggagatt ttagcttttc tgccttgcaa caagtggcag
    48421 ttccagctat tagcattgct ttattaggaa tgattgaaag cttgctatgt ggtgcttcgg
    48481 ctggccgaat ggcaaataag cccttagata gcaatcaaga attaatggcg caaggaattg
    48541 gaaatctgtt gcttcctttc tttggcggga ttcctgctac tgcggccatc gcccgtacaa
    48601 gcgtggccat caaatctggt gcacaaacta gattagctgg tatgatacat gcagttgtct
    48661 tactgctctc catgcttgtt tttgcgccag tgatgtcaca gattccaatg ccagcacttg
    48721 caggtgtttt gattgtgacg gcttggcgta tgaatgaatg ggaaacgatc aaggagctat
    48781 ttactaataa atattggtca gcagttctat tgtttatcct tacgatgatt tgtacagtta
    48841 tctttgattt aagtattgct atcgtgatcg gggtaatcgg cggctgtgta ttttttgttg
    48901 tcaaaagcgc tgctatcacg atttcattag aaacgatcga ttggcaaaga atggggctgc
    48961 cagaaacgga aaagctgaat aactggacag tagtgtatat tagtggtcca ctgtttttta
    49021 tgtcttcaga aaaactcaaa aataaattgg aagaactaaa tcatcacgat ggtgtcattt
    49081 tctccatgcg aggcgtacca agtattgatt tgacggcacg tgcagttttt gatgaatttc
    49141 aagaaaaagc agagcaaaga ggacaaacga ttatctatac ttccttgcag ccagaagtag
    49201 aaaaacaact ttctcacttg tgggaacata cattcacgca tcaacatcaa acagttgctc
    49261 atgcgttgac agctttacat gcgaaatata ctgcaattag ccattaaaac aatgaaaaag
    49321 aacagacaag actgtaaact gaagatttta tggtcttgtc tgttcttttt aatattgctg
    49381 taaaagtgaa gctagtactt gccagtcttg atggataaca ggtacaaggg agcgattgta
    49441 gaaaatagct gctggatgaa aaagtggaag aattcgatag tttttttctg accattcgta
    49501 ggcatccttt tgttctgtta attgtaagac aggccctgta tagagttgac catgattttt
    49561 ggtaaccgta tattctttgc caagtaaacg ttgaagacca atgtttccaa gtgtcgcaat
    49621 taattttggc tggaccttca tcagttcgta atccaatatt ggtgcatgcg caaatacttc
    49681 ggaacgagta ggtgtccgat ttggataaac agtttctgac tgttgtgtcc gtttattgat
    49741 ccgatgagtc acgcgatacg ggcggctcct tacagcactg gtgatataca cctcttctcg
    49801 tgttaagcca gttgaagaaa gtgcctgcat caattctttt ccagcttgac cgctaaaagg
    49861 aacatgcgta tcaatctctg ttttccctgg ggcttctccc acgagcatca gtttaggatg
    49921 aagaggtcct tgcccagcga taaatccttc tacaggacgg ccgttcattc ttaaagaagc
    49981 ttcttgtatc agttcttttg ggtattccat ttatgctcct cctttttctt ttattataag
    50041 aataaaagaa acacaatgcg actattttat ttggtagaac tgtgaggata gaaaagcaga
    50101 agtattgctt gaatttttgt tttacttttt gattttaaat ttagttgact aacggttgct
    50161 gttctggtaa gctagtactg ttgtaattgt ggactccaca gctacaaccg ctcagaacaa
    50221 gtaataagca cagcatatgc tgtcacttcg gatggcgagt ctaagtatat cagaaggagg
    50281 tgctttatag catgtacgca attattaaaa ctggtggtaa acaagtaaaa gttgaagtgg
    50341 gacaagcaat ctatgttgaa aaacttgacg ttgaagcagg agaaaaagtt gtttttgacg
    50401 aagttatctt agtaggcgga gaatctacaa aagtaggcgc tccaactgtt gcaggtgcaa
    50461 ctgttgaagg tactgttgaa aaacacggca aacaaaagaa agtcgttact ttcaaataca
    50521 aacctaaaaa acattcacac cgtaaacaag gtcatcgtca accatataca aaagtggtta
    50581 tcgacgcgat caacgcttaa tagcgtttga gaaagaaggc ctatatatga tcaaaggaac
    50641 atttaagcga aatgacgcag gtcagatcgt ttcattcact ttgaccgggc atgctgatgc
    50701 tggtccttat ggaagtgata tcgtttgtgc gggtgtttct gcgttagcga tcagcactgt
    50761 caacgggatt gcctcattag ccggttttga gccgattgtt gaaatgaatg aagaagaagg
    50821 cggttatctt tataccgaag tcacttcagg aatgacacaa gaacaaaaca atattgctga
    50881 gattctatta gaaaatcttt tattaggatt acaatcgata gaagctgaaa actcagaata
    50941 tatccaaatt aaaacaatta atgataaata ggaggtgcag accatgttgt tatctatgaa
    51001 tctacaatta tttgcccaca aaaaaggtgg cggttctaca tctaacggcc gtgactcaga
    51061 atcaaaacgt ctaggtgcta aacgtgctga tggacaaaca gttacaggtg gatcaattct
    51121 ttaccgtcaa cgcggtacaa aaatctatcc aggtgtaaac gtgggtatcg gtggagacga
    51181 cactttattt gcaaaagttg atggcgtagt acgtttcgaa cgtaaaggcc gtaacaaaaa
    51241 acaagtgtct gtttatccag tagctcaaga agcttaattg aatcttatga ttaaagaggt
    51301 tgtgacaaga cttttgtcac agcctttttt gtttataaaa ataaaagttg tagtggaggc
    51361 tacgaagttt actttgtctt tttacactta atattttttt gccaatttgg aatcaggatg
    51421 ttttgataac tatcgttttc aattgatgga agctatattg tttgctatca gtgaaataat
    51481 tatatggtaa acagtgttct ttttcttgtt tccattataa aaatcgtatc gggatttttc
    51541 gttcttttaa attgaacatt tctatctatc cgcgtgttat caacaaaaca aaatcaggta
    51601 aatagttgac gaaacagaaa taaatacata gtattatgtt ttgaagccta agtacaatag
    51661 tctatagaaa aggagcgata ccattggcaa aacgcattga ccgaatttat atgtatgtca
    51721 aagaaaaaac cgctcattta acaaaggcag aatatgatca aggagtaaca acacaggaaa
    51781 ttgctgaagt gttagggatt cagcgaacaa atagcagtaa agatctgaat cagctagtgc
    51841 gcgaaggaaa actgataaag acagacggac gaccagtacg ttacatatat caaacactcg
    51901 ttacgcacgt aaagccagtt acaaaacatg tagtcagtta caaagaaacg ccggtctctg
    51961 aagaaaaaaa tacactccaa atagatacta aggatatctt tgcaaaaatc attggagcta
    52021 acggcagcat gaaaaattca gtggaacagg caaaagctgc gattttgtat ccgccaagag
    52081 gattaaattg tttgattaca ggacctaccg gatcaggaaa gacttatttt gcacacgcga
    52141 tgtatcattt tgcaaaagcg catcatgtaa tagatgagga aacggaactg attgttttca
    52201 attgtgctga ttatgccaat aaccctgagc ttttgatgag tcatttattt gggtacgcaa
    52261 aaggtgcttt tacaggcgca gatgaagaaa aaatggggat tatcgatcaa gcggatggcg
    52321 gtatgctgtt tttggatgag attcaccggt tgccgcctga aggtcaagaa atgatctttt
    52381 actttatgga tcatggaact tacagtcgtc ttggggaaac aacgaaatcc catgaagcaa
    52441 atgtacggat cgtaggtgcg accacagaag acccaggttc ttctctatta gaaacttttg
    52501 ttcggcgtat cccaatcaat atcaaacttc cggcttttga aaaacgtcct gcaaatgaga
    52561 aagtcgattt agtaaaaatc atgattgccc acgaagcaaa ccgcacgcag cgaaagattt
    52621 ctttgacaga agatgtagca aaagcattga tcggcagtgt gacctatgga aatataggac
    52681 aattgaagtc aaatatccag ttagtatgtg cacgaggatt tctaaatcat atgcaatcac
    52741 ccgaaatctc gatcacaatc gatgatttga cagaagggat tcgtagcgga ttgattcaat
    52801 tagcaagcaa ccgcagtgca atggcagagc tttctaaaat attggagcca aagataactg
    52861 tagcaccaaa tgatacgatc atgaaaatcc aatcggactc ctatgagtta ccttataatc
    52921 tatatgatat catcggagat aaagcagctt tactgaagtc ggatggtttg gatcaagaag
    52981 caatcaatca tttcatttct acagatatca acatccatct gaagtctttc tataaagacc
    53041 atggtttttc ttttaatgca gacagcaaat tagcagaatt tgtagatccg aaaatcatag
    53101 aagtgaccaa tcagatttat gtaatggtca aaagatcttt accatatgag tttcagcaaa
    53161 actttattta tgctatgagc ttgcatatca gttctttttt gaaaaaaatc aacttaggag
    53221 aagaacggca tacgaatgat aacatccgtg agatggcttt tgattttcca gatgaatatg
    53281 ctgttgcgaa agaagtgcgt agttatatcg aaacgtattt tcaagtggag attccagaaa
    53341 gtgaagacta ttacttgacc gttctactcg tctcgttacg ggcaaatcaa gcaagcggca
    53401 gaatcggtgt agtcgttgca gctcacggaa acagcacagc aagcagtatg gtccaagttg
    53461 tccaacagtt gttagatgca gagaacgtac gagcagtaga catgcctttg gatatggatc
    53521 cgaaaacagc attggaccga attgaacgca atgtacaaga agtagatgaa ggaagcgggg
    53581 tcatactctt agtagatatg gggtcccttg cgtcgtttaa ttcgcaaatt caaagagaca
    53641 ctggaattcc agtacgtact gttgatatgg taacaacttc tctagttttg gaaactgtac
    53701 gaaaggtctc agtattaggg acagatctag atatgttgca tgaatcattg aaaaattttc
    53761 gaggttacgc agaaatatct tctgtagaat ctgttcagga agcaaaacct attcataaga
    53821 aaaaagctgt tttggctatc tgcgcatctg gcgaaggtac agcacaaaga atcaaagaat
    53881 tgatcgaacg agcggtaaac aagcgtcaag aaacagaatt agaagttcta gctttgtcga
    53941 ttgtggaagt gaaagaagaa ctgccagtta tccaaaaaga atatcagatc atagctacta
    54001 ctgggattac tgatttgaat atccaagccc catttattcc tttagaacgt tttattgatc
    54061 aaaatatcga agtcattttg gatcagttgc tgatggaatc agaattggag gaaactgaat
    54121 tcatctccct agatgaagag tcagctaaaa atacgtgtgt tgagtttatc tctgataact
    54181 tcatctttat taatggtagt aagttaatcg atccaatgtg gcaattttct acacaaatct
    54241 ctcagacgac gggaatcggc gatgaagaat atggattcaa aatcaaccta gtgatgcaca
    54301 cagcaggaat gatcgaacgt attattcgga atgaaccatt gactgtggaa gaaaacgaat
    54361 tgacaaatac aacgaatgat cctctttata gccaattggc agcctcagtt gttctgttgg
    54421 aagatcagat aaaagtaaaa gtgccgatag aagaaatgta ttatctgcta cgtctagtcc
    54481 ataatcagtt agataaaaaa gaatacactg tgccatgaat acacaaaaac gatacacttt
    54541 tatagtgtat cgtttttgtg tattggttaa gaatccttta aattcaatta gtgtatcgta
    54601 aaaaagttgg cacgcttttt gcttatagta gtgtgtgcta ggaggtggtt gttcacacag
    54661 aaatgatagg ggtttctgtg aagtagtgag gaagaaggag ttttgcagat ggatattcga
    54721 ttggcacgta tagatgatcg tttaatccac gggcaagtcg caacagtttg gtcgaagcaa
    54781 acaggtgttg aacgtatcat tgtgatcagc gatgtagtcg ctcaagataa attgagaaag
    54841 tttctactaa aagaagctgc accgccgggg atcacagcaa atgtaataac cgtgcagaaa
    54901 atgattcaaa tctatcatag tggattatta tcacgagcaa aagtgatgct tttattcacc
    54961 aatccccaag atgttgaagc ggttgtccgc tgcggtgtac agttgaagtc gttgaatatc
    55021 ggcggtatga gttttactga aggcaaatca atgattacca attttgtttc agtaaatcaa
    55081 caagatattg attcctttcg ttacttgaac agtcaagaag tggagttaga gattcgaaaa
    55141 gtacctgctg acaggaaaat ccttttgatg gaactactag cgaaaatcaa aaaggtgtag
    55201 caagaatggt tgttggaaaa ggtcaaataa ttctgttgta atggttagca attattaata
    55261 tttttgaatt tgttacaaca aaagtaaata ggaggtataa atatggtagg gattatccta
    55321 gcaagtcatg gacaatttgc tgaaggaatc ttacaatccg gttcaatgat ctttggcgaa
    55381 caagaaaacg tcaaagccgt gattttgaaa ccaagtgaag gtccagatga cttgagagcc
    55441 aaattggaag aagcggttgc ttcttttgat aatcaagacg aagtgttatt cttagttgat
    55501 ttatggggcg gaacaccgtt caatcaatca aacacattat tcgaagagca caaagataaa
    55561 tgggcaatcg tcagcggttt gaatttacca atgttgattg aagcctacgc atcacgcttt
    55621 tcaatggaat ctgctcatga aattgcagca cacatcattg aaacagcaaa agacggtgta
    55681 aaagtaaaac cggaagaatt agaaccggca gaagcaccga aagcagcagt tgaagacgca
    55741 caacctaaag gagcacttcc agaaggaact gtggtcggag acggaaaaat caaatatgta
    55801 ttagcacgtg ttgactcacg tctgttacat ggacaagttg cgacagcttg gacaaaagca
    55861 gtgcaaccaa accgtattat cgttgtttca gatgcagtat caaaggatga tctgcgtaag
    55921 agactaatcg aacaagctgc tcctccaggt gtaaaagcaa atgttattcc tattagcaaa
    55981 atgatcgaag tagcaaaaga ccctcgtttt ggaaatacca aagcattgct tttatttgaa
    56041 aatcctgaag acgtattgac agctgttgaa ggtggcgtag acatcaaaga attaaatgtt
    56101 gggtcaatgg cgcattcggt cggtaaagtc gttgtaagta aagtattgtc tatgggacaa
    56161 gaagacgttg aagcgtttga gaagcttgaa caaaaaggtg tgaaattcga tgtacgtaaa
    56221 gtacctaatg attcacgcga taacatggat gatattttga aaaaagcaaa agctgaatta
    56281 gcaaaagcgt aataaataat attaaaattt ataggaggct tatcatgtct attatttcaa
    56341 taattttagt cgtattagtt gcctttctag ctggtatgga aggtattctt gatgaatttc
    56401 aatttcatca accactagtg gcatgtacat tgatcggttt agttaccggt aacctcgaag
    56461 ctggtatcgt acttggcggt acgcttcaga tgatcgcttt aggttgggca aatatcggtg
    56521 ccgctgtagc accagatgct gcattagcat cagtagcatc agcaattatt ttagttttag
    56581 gtggacaagg tgttaaaggt gttccttctg cgatcgcgat tgccgttcct ttggctgttg
    56641 cagggttgtt cttaacaatg atcgtacgta caatcgctgt tccaatcgtt catttgatgg
    56701 atgcggctgc tgaagaagga aacatccgta aggttgaaat gtggcacatc attgctgtat
    56761 gtttacaagg ggttcgtatc gcggtcccag cagcagcgtt gctatttatc ccagcacaaa
    56821 ctgtgcaatc attccttgaa tcaatgccag catggttaac agatggtatg gctatcggtg
    56881 ggggaatggt cgtagctgta ggttacgctt tggtaatcaa catgatggct acaaaagaag
    56941 tatggccatt cttcgttatt ggtttcgttg tagctgcaat ttctcaatta acattgattg
    57001 ctctaggtgc tttaggtgtt gcattagctc ttatttactt gaacctttct aaaatgggtg
    57061 gttcatcaaa taatggaggc ggaagcaact ctggtgaccc tttaggcgac attttgaatg
    57121 actattaatc ttgaaggagg aaaataaaat ggcagaagaa aaaatcaaat tatcaaaaaa
    57181 agatcgttta gctgttgcgt ggcgctctac cttcattcaa ggttcatgga actacgaacg
    57241 tatgcaaaac ggtggctggg cattttctat gattccagca atcaaaaaat tatacaaaac
    57301 aaaagaagaa cgttctgcag cattaaaacg tcacttggaa ttctttaata cacacccata
    57361 cattgcttct ccaattttag gggttacatt ggctctggaa gaagaacgtg cgaatggcgc
    57421 gcctgttgat gatgtagcga ttcaaggggt taaagtaggt atgatgggtc ctttagctgg
    57481 tgttggtgac ccagtgttct ggtttacagt acgtccaatg ctaggtgcac taggtgcttc
    57541 attagctatg ggaggaaata tccttggacc aatcatcttc ttcttaggtt ggaacattat
    57601 tcgttgggca ttcatgtggt atacacaaga atttggctac aaagctggtt ctaaaattac
    57661 tgatgacctt tctggcggat tgttacaaga cgtaacaaaa ggtgcttcaa ttttagggat
    57721 gttcgtatta gctgcccttg tacaaagatg ggtatcaatc aaattcttac cagttgtatc
    57781 aactgtaaaa ttagataaag gtgcttacat cgaatgggat aaattgcctt caggtggtga
    57841 aggaatcaag agtgcatttg aacaagttaa taatggctta gccctttctc ctgaaaaggt
    57901 aacaacatta caagacaact tagaccaatt gattcctggt ttagctgcat taggattaac
    57961 attgttatgt atgtggttgc ttaagaaaaa ggtttctcca atcgttatca tccttggttt
    58021 attcgtagtc ggtgttgttg gacacgtcat cggactttta taatccataa aaatatagct
    58081 cgggcgttgt cccgagcttt ttttatatag tatactgttc ataaacaaat atctggaggg
    58141 agaaaatggt tcaatcaatc aatacaaaag tagacttggt aattgatgct acttcgttta
    58201 cgggtctgac agattacggg caaatcatga taggtgataa tggttttgag ttttaccatg
    58261 cgcgagatag acgcaaatat atccaaattc catgggaaga agtggattat gtactagcat
    58321 cagtcatgct aaagggaaaa tggattcctc gatatgccat tcaaacgaaa aaaaatggta
    58381 catacacatt ttcttccaaa gaacctaaaa aagtgcttcg tgcgatcaga gaatatgtag
    58441 atgaagatag aatggtacaa tcattgagtt tctttgatgt agtgaaacgt ggtattcgta
    58501 gtatgtttaa acgcaagtaa aaaataaaga aaacttctaa gaggaggttt tctttatttt
    58561 tttactttgc agaagaaaat atgaaatagc aaaaccaatt atttgtcccc tttaaatccc
    58621 atatgctaaa attgattagc aaagaaggag gttatattat gagttggtta tggacattga
    58681 ttgttggagc cgtgatcgga gcaattgcag gtgcgatcac cagtaaagga aattcgatgg
    58741 gctgtgtaac gaatatcatt gctggactag tcggttcaag tattggacaa gcgattttcg
    58801 gcgaatgggg accaaaagct gcaggtatgg cacttattcc atctatttta ggcgcagtga
    58861 ttttggtagc agttgtctca tttttctttg gaaaacgatc ataagttttt acaaaatagt
    58921 aaactaaaag gagttgcagc gagactgtga ctcctttttg gctttattta tttaaaataa
    58981 aaagaagttt tccggaaatt tttatttaac tgtcgtgtac gaagaaaagt ttgctataat
    59041 ggaaaaaagc gtgcaaagaa agagggagtt tcattatgat gctacgtgta gaaaaattgc
    59101 gcaaaaaaat gcaagaagaa aatttggatt catttttggt taccagtccg tacaatcttc
    59161 gttacttaac gaactttaca ggtacgacag gattagctgt tattactttg gaaaaagcat
    59221 tttttattac tgattttcgt tataccgagc aggcggcagc gcaggctcaa gggtttgaaa
    59281 ttattaaaaa tgtcggacct atttttgatg aggtagcaaa cttagtacgc aaagaagaac
    59341 tgcactcatt agcttttgag gaaacaacag tctcattttt agaatattcg gttttagaag
    59401 aaatcatcga tgcggaatta gtacctgttt cacagatgat cgaagaactc agagaagtga
    59461 aagatgaaga agaaatcgct attatcgaaa aagcatgtca tattgcggat atggcatatg
    59521 atcacatcct gaaaatgatc caaccgggca tgactgagat tgaagtcgca aatcaactag
    59581 acttttatat gcgttctctt ggcgcttcag gtgtttcttt tgatacgatc gttgctagcg
    59641 gattgcgttc ggctatgccg catggtgtag caagcaaaaa aatcatcgaa caaggtgact
    59701 tgatcacatt ggactttggt tgctattacg aagggtacgt ttccgatatg acacgtacat
    59761 tcgctattgg tgatcctggg gaaaaattaa aagaaattta tcaaatagtc ttagatgctc
    59821 aattagcagt tattgatgct gcaaaaccag gaatgactgg tgtccaatta gatgcagttg
    59881 ctagagatta tatttcaaaa catggttacg gggaagcatt tggacattct acaggacatg
    59941 ggatcggttt agagatccac gaaggaccaa acgtttcttc tcgtgcagaa aagcaatttg
    60001 taccaggaaa tgtgatcact gatgaaccag ggatctactt accaggaatc ggtggagtac
    60061 gtattgagga tgacttgttg atcacagaag atggaaatcg tgtgttgact cgttcaccaa
    60121 aagaattgat catcttatag tttcatcaat agaagaagta agcgtaaaaa tcagtgttca
    60181 cagactttgt tatagaaaat cactcgattt aatgatacac tatagaagaa cttttaagct
    60241 gtaagagata ataaagttgg gtgttttctc caattcatag cagtttgcag ctgatcggcg
    60301 gcagttttct taccacgtga tcactatgcc gcatcataga gaattcggat gtatctcgtg
    60361 cttaggcaaa gggaggaata aataaatggc agatgaaaaa aatttgattt taaacgcaaa
    60421 ccaagattta ggagagatcg tgatcgctcc tgaagtcatc gaagtaatta tcgggattgc
    60481 agcttctaaa gtagaaggcg tatacggaat gcgcggaact tttgccagca atgtcactga
    60541 attattagga cgtgcagctc acggaaaagg tgtttactta gcaaacgagg aagatggctt
    60601 gaaagtagat ctttactgtt atctagaata tggtgtttca gttcctaaag tagcaatgga
    60661 aatgcaggaa cgggtcagcc agcaagtcct tttcatgacg gatatcgatt tatctgaagt
    60721 caatatccat gtagtagctg ttgttcctga aaaattagaa caaccaacaa tcgaagaact
    60781 ttttgaagac gaagaggaag agaatgaata aagaattatc aagacacgag attcgggaaa
    60841 tggcattgca ggctttattt ccattagact tcaatgcaga cctaacaaaa gaagatgcga
    60901 ttttcaacgc aatcgaatta gaccaccgcg acatgatcaa cgaagatgaa tcagagtttg
    60961 ttcctgttta tcttgatacg ctagttggcg gtgtctgtgc aaaaaaagat gaattggata
    61021 aagtgattga aaaacattta aaaaacaatt ggcacatcaa tcggatctca aaaatggatt
    61081 tggtgatctt gcgtatcgcg atttttgaaa tgacttatgt gacagatgta ccagcggctg
    61141 ttgctttaaa tgaagcaatc gagttggcaa aaacatttag tgatgaccgt tcacgtaaat
    61201 tcgtcaacgg tgttttatcc aatgtattga aagaattaga agctggggcg taagtcctag
    61261 cttttttcta tgaatcatca taaacctgtt ataaatcggg aaaattctat ggtagaatga
    61321 aaacacaaaa aatatctggg agtggttaga tggcagaatt gattaacgga aaagaattag
    61381 ctgaaaaaat gcaggcagag attgctgaaa aaatccaaaa attgaaagat aatggtatcc
    61441 atcccggatt agtcgtttta ttggtagggg aaaatccagc cagccaaatc tatgtaagaa
    61501 ataaagaacg tgtagcaaaa gaaatcggaa tccattcatt ggtagagcgt tatcctgaga
    61561 cgatttctga agacgaacta cttgcagaaa ttgaaaaata caatcaagat cctagttttc
    61621 atggtatatt ggtccaatta ccattgccaa agcatataga tgaagaaaag atcctgttag
    61681 ctatccgccc tgaaaaagac gtagacggtt ttcatccgat gaatttaggc agactccttg
    61741 cgggtaaacc ggacaagatt ccttgtactc catacggcat catgaaaatg tttgaagctt
    61801 attctatcga tccggcgggt aaacgagcag tagttatcgg acgaagcaat atcgtcggta
    61861 aaccgatggc tcagctactc ttgatggcag atgcaactgt tactgttgct cattctaaaa
    61921 ccgaaaatct ggctgaactg gcacaagaag cagatatttt agtcgtagca ataggacgtg
    61981 gacattttgt cacaaaagaa ttcgtaaaac caggtgctgt agtgatagat gtagggatga
    62041 atcgtgatgc taacggtaag ctgatcggtg atgtgaaatt tgatgaagtg gagcctattg
    62101 caggctggat cactcctgtg ccaaagggtg tagggccaat gactatcacg atgctgatgt
    62161 atcaaaccgt aaaatctgcc gaagcttttg gagcaggtga atagatggca caagaatatt
    62221 taactgtcac tacattaacg aagtatttga aaagaaaatt tgatgccgat ccttatttag
    62281 aacgcgtata tttaacaggc gaaatatcga atttccgttt acgtgccaat gcccatcaat
    62341 atttcagctt aaaagatgac catgcaaaaa tatctgctat tatgttcaaa ggagcattcc
    62401 aaaaattacg attccagcca aaagaaggaa tgaaagtcct tgtcgttggg cgtatttcat
    62461 tatatgaagc gggaggttct tatcaaatct atgtagagca catggagcct gatggaatag
    62521 gtgctttata tcaagaattg gaagaacgaa aagaaaagct gatgaaggaa ggcctttttc
    62581 aagggcctaa aaaaatgctg ccacgtttcc caaagcgaat cgcggtcctt accagtccaa
    62641 gcggagcggt tatccgcgat atcatcacga cggtgaaaag aagatatcca attgtccaat
    62701 tggttttgtt cccaacagtt gtacaaggaa accaagcagc ggacaatgtt gtcaggaata
    62761 tccagagagt agaagagatg ggcaatttcg atacaatgat catcggtcgt gggggtggtt
    62821 cgattgagga tttatggccg tttaatgaag agcgggttgc tcgggcgatt tatcaagcta
    62881 atacgccggt gatttcatct gtaggacatg aaacagatac cacgatcgct gatttagtag
    62941 cagatgttcg ggctgccact ccaacagcag ctgcagaatt agctgttcct gttttgtcag
    63001 aagagttgat gcgcattcaa gaacggcaag ctagattgca gcaggcgttt gtacgccaga
    63061 tccagcgcaa acaagaacgg ttcgagcgtg ctcgacgttc ctatgtattt cggcagcctg
    63121 aaagattgta tgaaggtcag accatcaaat tagaccagtt gaaacagcga ttatatcaag
    63181 ctacacagca aatttatcat gcgaaagaaa aacaaacgat cgcattaagc caccaattgg
    63241 aacaagtggc tccgctttat cgagttaaag cagctcgcca agaaactgct tatctagaaa
    63301 aacgcttaga agagaaaatc caacaatata tgaaacaaca gcagcagcgt tttgctcaag
    63361 ctgttcaatc tcttgatttg ttgagtccat tgaaaatcat gggaagaggc tacagctata
    63421 cgacgttaaa tgatcaagta gtaaaaagtg tcaccgagat tcatcaaggg gatttgctga
    63481 cgatccatta tcaagatgga atcgttaaag gacaagtaca agagatagac aaaggagaat
    63541 aaaaatatgg aaaatccaac ttttgaagag tcactgcaag aattagaaaa aattgtcatg
    63601 cagttagaac aaggagacgt tccattagaa tcagctctag attcgtttaa acgaggaatg
    63661 gaattaagca aacattgcca agatacatta gctaaagcag aagagacctt gacgaaaatg
    63721 atgacagaat caaatgaaga agttgatttt gacggaaacg aggaaagctg agatgagatt
    63781 aactgacttt tcagctattc atctacctgc tgtagaaaaa gaaatcttgt cttttttaga
    63841 tgagcataca acggatagag gactctatga tgcgatgagt tattcagtga aagcaggcgg
    63901 gaaaagaata cgtcccttat tacttttaac ggccgttgct tcctttgatg agcctattga
    63961 tgttcccgtc tatcaagtag cagctgcttt agaaatggtg catacgtatt ccttgatcca
    64021 cgatgatttg cctgcgatgg acaatgatga tcttcgtaga ggaaaaccta ccaatcataa
    64081 agtattcggc gaagcattag ctatattggc cggagatggt ttgcttacag gagcattcca
    64141 gctaatcagt atggcacact taggtaattc tcctaagctt ctgctgcttc agcaattagc
    64201 tgtttgtgcg ggatcacaag gtatggttgc tgggcaagct gcagatatcg agggcgaatc
    64261 gaaaaagctt tctttagaag aattagcatt tattcatgaa agaaagacag ggcatttgat
    64321 tcgttatgcc ttgctggctg gtggcatatt agcgaagcaa cctgaagaaa tcttattgct
    64381 acttcaacga ttagccgaac atttaggttt agcttttcag ataagagatg atctactcga
    64441 tgtgattggt acaacgaaaa cattagggaa aacagctggt aaagatgaac gtatggaaaa
    64501 aaatacttac ccgcgtttat taggcctaga aaagacacgt gaggcgttgg agattgagct
    64561 gttatccgcc aacaagatca tagacaaatt agaagaggac gttttttctt ttgatggcgg
    64621 gctgatgcgc cagatgatca agcaatttga tgtggagaaa tgagggaaag aatggaaaaa
    64681 gaacgcgtag atgtattagc ggtcaaacaa ggattatttg aaacaagaga acaagccaaa
    64741 cgttcagtga tggctggttt gatttacaac gaaaaaaacg agcggtttga taaaccggga
    64801 gaaaaaattc cagtgagtag tgaattaaga gtcaaaggta aaaaacttcc ttatgtttct
    64861 cgagggggat taaaattaga aaaagcactc aaagcatttg atctatctgt tgaaggaaaa
    64921 acattgttag atattggtgc atccactggc ggatttactg atgcagcttt gcaaaatggc
    64981 gcaaaaatga gttatgcttt agacgttggc tacaatcagc tagcttggaa aataagacaa
    65041 gatcctagag tcgtcgtaat ggaaagagtg aattttcgtt atgcaaaacc cgaagacttt
    65101 accttaggaa ttccagaagt tgctgttatc gatgtttctt ttatttcact aaaactgatg
    65161 ctgcctccat tacatgctat tttaaaagaa gagggagaag tgattgcttt aatcaaaccc
    65221 caattcgaag caggcagaga agctgtaggg aaaaacggaa ttgttcgtga ccctcagacc
    65281 catcaaaaag ttttagaaga cattttgtca tttgcggcac aaggtggata tgatgtgctg
    65341 gaattaagtt attctccgat cacgggggga gaaggaaata tcgagttctt ggctcacttg
    65401 aggaaagtac ccgaaagcgg aacaatcaat tcagctatta atatggcaga agtggtttca
    65461 aatgcacacg aacagtttga ccataaataa attgtaactg tgaaaatcaa gtgagaagta
    65521 tgcggattct tctttattat accaaggaaa taagctatca ttgattaaga agaatatgct
    65581 aaggagcgaa gacgtaatga gaaaaaaaga tcggcatcgt ttgattactc gattgttgag
    65641 tgagcaagat atccgaaagc aggaagaatt tgttgaaatc ctgaaaagca aaggaatatc
    65701 tgttactcaa gctacgattt ccagagatat aaaggaactg aaactgatca aggtaccggc
    65761 ttcagatggc ggctaccgtt atagcatacc agctgaaaca aacgaagatg taaatactaa
    65821 attggaaaaa ctattaaaag acgctttcgt ggcagttgac caaatggaaa aatttgttat
    65881 tttgaaaaca ttgccgggaa atgcttcggc agcagcaaat ttgattgata aacgttacaa
    65941 gaaagaatta ttttcgatta tcaatgatga cgataatgtt ttgatgatta cacgaactga
    66001 agaccaggca gttttattga agaaagactt cctgcattac ctttaagttg aggagcgaat
    66061 gtgatgctac aagaaatcag tattactaac tttgcgatta ttccggaatt gcggctttct
    66121 tttcacgaag gaatgaccgc gctgaccgga gagactggtg cgggtaaatc cattattatc
    66181 gatgctttag gtctgttagc aggaggaaga ggttcaagcg attatatacg tcaaggagca
    66241 gaaaaatgtg tgcttgaagg gttgtttgaa ctaccaaaac aagaaggatt ctctgaactg
    66301 atggttgaat tagggatcga aacagatgag gacaatctga ttgttcgacg ggatatgtcc
    66361 ttaactggaa aaaatgtttg tcgagtgaat ggtcatatta tcacattagc taatctgaga
    66421 agaatcggca gttatttagt agatatccaa ggacaaaacg aacatcagga actgctccag
    66481 cctgaatcac atcttgcttt attggatcgt tttggagatg tagctttcca acagaagaaa
    66541 aagagttatc agcaagaata tatctcttat cgtgagctgg aaaaaagggt acgaaaagtg
    66601 cagcaaaatg aaaaatccta tgttcagaga atagatatgc tccatttcca gcaagaagaa
    66661 atagctgctg ctgatttgca agtcggagaa gaagagaaat taaaagaaga aagagaaaaa
    66721 cttagcaatt atcaaaaaat tgctgatgga ttagctgcag gttacggagc actgacgaat
    66781 aatgaacaaa acagtgtaga tggtgttggc ttggccgttt cagaactgca agggatcgcc
    66841 catctagatg tggagtatga agcaatttat gaaaatatcc aaagtgctta ctatttgctg
    66901 caagatgcaa tcggcgatat gagtcgtcag attgatttat tggagttaga tgagagtcgt
    66961 ttagaagaag ttacgcaacg tttagaatta atccgacagt tgaaacgtaa atacggcgaa
    67021 tccattgagt caatattggc ttactatgac gaaatcaccg aagagctagc ttcttctgat
    67081 ttttcagaag gtcaattgga caaaatgaaa gaggaactag agcaaaaaga gcttctactt
    67141 cagcaacaag ccgcagatct tcatgaagcg cgtaaaaaaa tcgcaaaaga attggaaaaa
    67201 tccattctgc atgaattgaa aagtctgtat atggaaaaca ctgagtttga ggtacgtttc
    67261 ttaaaagaag aaaatagaca attgaatcat gatggatttg accaaatcga attttatatt
    67321 acgaccaatc caggagagcc actgaagcct ttggtgaaag tcgcttctgg tggcgaactg
    67381 tctcggatgt tgcttgcttt gaaaactatt ttttcttctg agcaaggtgt gacaagtatt
    67441 atttttgatg aagtggatac aggtgtgagc ggaagagttg cacaggccat cgcagataaa
    67501 atttctcaaa tatcgaaata ctctcaagtt ttgtgcatca ctcatctgcc tcaagttgct
    67561 gcagtcgccg actatcaata ttatattgtg aaagcagtga ttgatggacg tacgcaaact
    67621 tctgtttcag agttgaaaac aaaagaaaga gaagaagaaa ttgcacgtat gctggctgga
    67681 agtgagatta caaaactcac actcgaacat gcaaaagaac tattgaaact cgcaaaaagg
    67741 acctgagcca cctcgcagtg gttcaggtcc ttttcagcag ctgatagcta tattttattt
    67801 ttacatgaca ctcattacag cagtcaatac aacagatcca atcgttaaaa tcagcattgt
    67861 ccaaatgaca aattttgtta ctttagcaaa agtacttgtt tgtttttttt cacgcattgt
    67921 tttcaacctc gtcattaatt agttgattca agtgtacaat cttttttcca tttccacaag
    67981 agggcttttt tataaaaact tccctttttt taaataatag gtagttacga tacaaataaa
    68041 taatgttaat agaactagcc atataaaggc atcatccctt tcagcaatag gtaacttaat
    68101 gttcattcca tagatactgc cgacgattgt cggtatagtt aaaataatcg ttaaagaagt
    68161 taaaattttc ataatattat tcagattatt cgatacgatt gctgaaaaag tctgattcat
    68221 ttgttctact agttttaatt gaatgcgaga agtagtcatt gcctgctctg tttccaccaa
    68281 tacatcacgt aaatgatttt tcaaagcatg attttcttgg aaaagtttat tttgcgctag
    68341 ttctttcaat gcatctaaat tagcagaagt cgcttctctg aaataaacga ggcttttttg
    68401 gatatccatg atttgataaa gttgtttgtt ttcagtggat acttgaagtt tggcttccaa
    68461 agtatcgcat tgagattgaa gcgtagctaa ataactgttg taagagagtg tgacctgcca
    68521 aatgaattga aagaagatat tgagattagg cgaaatatca ctttttggaa aggtctggct
    68581 aaagactttc tttaaaaaca gtggttcatg attcgtaatt gtgataagct tctttttggg
    68641 cgtcaaaata atagagagcg ggtatgtatc cacttgaaaa taaccgctag gacttgtttt
    68701 agcaaaagga tattgtaaca ataataacgc tggctttgtc aactttgatt gattgaattc
    68761 ttctgtacgg gaattttctg catcgtccaa tatggaagtg atgtaatctg acggaatttc
    68821 aaattgatgt gtcagctgat gaatctcttc ttgattagga cgttctacac aataccagat
    68881 cgtttggtca gtttcctttc cggtattacg cagtttctca ttatctaatg taaaatattt
    68941 gatcatgatt ttcctcctgt tgcctgtttc ttttattata acggataggg aattggaata
    69001 catggaatgt gtttgtaaga tatagaatat aactgcataa atttaaataa aatgaaacag
    69061 ttgtgtaaag tatatacagt atacttgaag caacgataaa aaaggagttt acgttcatgg
    69121 gcacattcac accacttatc ttgttttggt atatttaccc ggtaatcgtt ttgtttggtt
    69181 gccaatttct tgtaaaatta ttttcgttaa atcgtcgttt taaaataaaa gcccctgatt
    69241 tggcgattcc ttttttgtgg ggcggtatgc atgcattgtc tagaaataca gggacaattt
    69301 ctatcttacc gtttttcttt atttctgttt tgctaatggg aatttgtatt gctgttttcc
    69361 aagcatatta ttatgaagaa attatttatc cgcgttattt caagatgact tggcgtttgg
    69421 tttttctgtt gacaatcgtc ttgtacgctg tcttgatcat tgtgaacata ctttcttacc
    69481 tatgaaaaaa atagaaaagc tgtaaaaagt cttttaaaag gctttttgca gcttgatttt
    69541 taaaaaaatg tttatgaata aaaaaagttg ttcccggatt tcccagaaaa ggtggtagaa
    69601 agtgggggat tgtggtagac taattttagt tagtggagga atggggggct ttcaatgttg
    69661 atgggtgaat tccaacataa tattgatgca aaaggacgtt taatcgtgcc ctcaaaactt
    69721 cgtgaagaac ttggcgaaaa gtttgttctg acacgcggat tggatggctg tcttttcggc
    69781 tatccgatga gcgaatggga aaatctggaa gctaaactga acgaaatgcc gttggctaaa
    69841 aaagacgcac gtacttttgt gcgattcttc tattcggctg ccactgaatg cgaacttgat
    69901 aaacaaggac gaatcaatat acccagcacg ttaagaaatt atgcagcttt gacaaaaggt
    69961 tgcgtagtca tcggtgtatc taaccgaatt gaaatttggg atgagacacg atggcaagat
    70021 ttttctgcag cagcagaaga gaactttgac gaaattgctg aaagtatgat tgatttcgga
    70081 ctataagaat aggaagaggc tgactaatga ctgaaacatt tcaacactat acagtcatgt
    70141 tgaaagaaac ggtagatgga ttgaacatca aaccggatgg cgtttatgta gactgtacac
    70201 tcggcggtgc cggacatagt gaatatttat taagccaact aagttctaaa gggcatctgt
    70261 atgcgtttga ccaagatcaa aaagcaatcg atcacgccaa gctgcgttta gcttcttatg
    70321 tcgaacaagg tatggtcaca tttatcaaag cgaacttcag agaattagaa gaacgcttga
    70381 gtgagcatgt agataaggta gacggcattt tgtatgatct aggggtttcc tctcctcagc
    70441 tagatgaagc agaacgtgga tttagttatc atcaagatgc accgttggat atgcgcatgg
    70501 atcagtcagc tcctttatcc gcttatcacg taattaatga atattcctac catgaattag
    70561 taaagatttt cttccgctat ggcgaggaga aattttccaa acaaattgct cgtgaaatcg
    70621 aacgagtacg aaaaacaaaa ccaatccaaa caactggtga gcttgtcgaa atcattaaac
    70681 aagtcatccc agctcccgca agaagaaaag gcgggcatcc tgcaaaaaga atttttcaag
    70741 ctgtgcggat tgcagtaaat gacgaactcg gtgccgaaga ggcctcttta gaacaggcaa
    70801 tccggttatt gaaagtcaat ggaagaatca gcgtaatcac attccattca ttggaagaca
    70861 gaattgtcaa aagtatgttt aaagaatata gtacggtaca agatctacca ccgggacttc
    70921 ctgtcatacc tgacgaattc caaccagaac tgaaagtcat tactcgtaaa ccaatccttc
    70981 cttcagagga agagctaaca gaaaacaatc gatcacgcag tgcaaagtta cgtattgcag
    71041 aaaaaataag aatgaaagag gagtagaatg atggcagaat taaagaaaat gcaagattac
    71101 gaatatgatt tacctgaatt ggtggatcag ccggaacaac aaatgcctga ttcttcttcg
    71161 aatcaagaaa tcattcttcc acaatcaccg gcaaaacgat taaagcagat ttctgctttg
    71221 gaaaaaattg ctgtggcaag cgtggcgatt gctattgttg ctttatgtgt tttaacagtt
    71281 atgctgcgca caaatatcag cggagctgaa aaagaaatca cgtcaataca aacagaaatc
    71341 aatgataaaa agcaagaaaa aacgagttta gaacaagaaa aaaacgaact ttctcgtact
    71401 gaacggatta aacaaatcgc agaagaaaaa ggattgtcta ttaatgacga caatttaagg
    71461 ataaggaaag tgaagtaaat gagtcttaaa aataaaattc ggcggtttat ggaaaagaaa
    71521 aatctaaatc cgatgaacaa tcgcaaaaaa gtaggtatca ttttatttgc tacgagtatt
    71581 ggattgttct ttttatttgc cgtccgtttc tcgtatatcg ttattggagg tcatgttgct
    71641 ggtacctcat tagctgaaaa aacaaaacag ttgtaccaag gaagtgaagt agtaaaagca
    71701 aaaagaggaa cgatttatga tcgtaacggt gtggcgctcg cagaagatgc ctcctcttat
    71761 tcaattaaag cgatactctc aaaaacatat acctctgggg ataaaaaact gtatgttgaa
    71821 gaaaagaatt ttgataaaat agcagaaatc ctgcataaga atctttctat agacaaaaaa
    71881 gatgcactga atattttaga ggacggcgca aaaaaagagc tgtatcaagt tgaatttggt
    71941 agctatggga aaaatatctc ccaagaaacc aagcaaaaca tcgaagcgga catgaaaaaa
    72001 gaaggtgtcg ctggtcttta ttttgtcgac catcaggctc ggatgtatcc aaatggcgtc
    72061 ttttcttctc attttattgg atacgcagtt ccagacaaag atgagaatgg cttagttggt
    72121 aaactaggtt tggagtctgc ttacaatgat atcttgagcg gtaaagatgg taagattatt
    72181 tatcaaaaag ataattttca aaatcctctg ccaggtacag tggcagaaga agaaaaagct
    72241 gtcgacggac aagatatcta cacgacttta gacagcagac tacaaagtta tttagaaaca
    72301 ctgatggatc aagtaaatga agaatatcag ccagaagaat tgacagcagt cctgatgaaa
    72361 gcaaaaaccg gagaaatctt ggcaatggga caacgaccta ctttcaatcc tgaaacaatg
    72421 gaaggattga ctggaaaaga tgctatctgg cgtaatttct tggtacaaga tagttatgaa
    72481 ccaggatcaa ccatgaaagt tttcactact gcagctgcta tcgaagaagg agaattcaac
    72541 gagaatgaaa ccttccaatc tggaaaaatc caagtagaag atgctacgat caatgaccat
    72601 gactttggtg aaaaaggtgt gctgaccatg cgtcaagctc tttcatggtc aagtaacgtc
    72661 gggatggtca tactggaaca gcgattaggc ggacgatggt ataactattt acaaaaactg
    72721 ggatttggac aaagtactca ttctggatta gatgatgaag taaacggtgc tttacctaca
    72781 ttaaatattg tcgaccgagc aatgagtgct tatggacaag cggtaggtgt gacgaatttc
    72841 caaatgatga aagctttcac ttctattgcg aataacggta caatgattca acctcgatat
    72901 atcagcaaag tggtggatcc ccaaactgga gaagagcgaa caactcaaac agaagttcta
    72961 gggcaacctt tttcaaaaga aacaacagaa aaagtccgtg aatatatgag agatgttgtc
    73021 gaaagcgaaa actacggtag tgcttatggt gtatatagtg tacctggata caatgtatcg
    73081 gcaaaaaccg gaacagccca aatcgcttct gatacagggg gatatcaaac aggagataca
    73141 gcctacctgt attcgattgt ggagatggtt ccttctgaag atccagacta tgtcttgtat
    73201 ctaacaatga aacaccctaa gacatatgat cgaatggcat tggctaaaat cgcaaatcca
    73261 ttgatgaaac gggcaatgga ttttaaagaa actgaagaag attcagatac agaaacaaaa
    73321 acagaaaaag tatccgtagc cgattatcgt aatcttgaag cggacgttgc agcagctgat
    73381 gctcaaaaaa gtggactgca acctgtagtg atcggtaatg gtaaaaaagt acaaaaacaa
    73441 tctactgcca acggtgatca gttgatctct ggagaaaaac tgatcctata tactggtggt
    73501 gataagctga tgcctgacgt aacaggatgg tcaaaagcag atatcatgaa gctggggaaa
    73561 atcctcggta ttgaagttag ttttgatgga gatggttatt gtgtcaaaca agaacttgct
    73621 ccatatgaaa aaatcactga agacaaactt agttttactt tagaagaata agaagagaaa
    73681 taggagagaa aagagcatgg aatggacaca agcattgatt cccattgtca gcagttgtgc
    73741 aatgacaatt gccgcaatgc cgctatttat tggttatttt caaatgaaaa agcaaggtca
    73801 ggcgattcgt gaggagggac caaagtggca caatagcaaa gccggaactc ctacaatggg
    73861 cggcttagtg tttctgatcg gctctatttt gacaggaatt tgggttggag cttggcaaaa
    73921 acagctaact cctactcttt tcatcttgct ttttgtatta gcgttatacg gagtaatcgg
    73981 ctttcttgat gattttataa aaatattcaa gaaaagaaac atgggactga actcgaagca
    74041 gaaattgatt ggacagattc tagggggaat catcttttat cttgtttacc gttctgaagg
    74101 ttatccaggt gtattgaatt tcttcggact agatctacct ttaggaatca tttatggtat
    74161 tttcgctctc ttctggcttg ttggattttc aaatgcagta aatctgacag atggcatcga
    74221 tggattagtt gctggcttag gaagtatctc ttttgcagct tacggtctaa ttgcttggca
    74281 tcagcatcag tatgatgtat taatcatttg cttaagtgtt ttaggaggtt tactgggttt
    74341 cttcgtctac aacagaaaac ctgccaagat ttttatggga gatgtcggtt cattagcgtt
    74401 gggcggactt ttagcggcaa tttctataat gctaaaccaa gaatggacat tgcttttgat
    74461 tggtttgatc tatgttatgg aaacagcaag tgtgatgctt caagttactt cctttaagct
    74521 tacaggaaaa cgaattttta aaatgtctcc aattcatcat cactttgaaa tgtgcggatg
    74581 gtcggagtgg aagattgata cagttttttg gttgatcagc attgtgactt cgttgatcac
    74641 attatggatc gtttggtagg agatgacggg aaatgaaaaa aatatcaaca tatgaaaata
    74701 agaaagtgct tgtcttagga ctcgcaaaaa gcggagtaag tgcggccaaa ttattacatg
    74761 aattgggcgc acttgtcacc gttaatgatg gaaaaccttt tgacgaaaat ccggaagcac
    74821 aagagctgct ttctttaggg ataaaagtaa taacaggtag tcatccaatc gaattgttgg
    74881 atgaagaatt ttcattgatg gtcaaaaatc cagggattcc ctacagtcat cctttagtag
    74941 caaaagccca agaaatgggt attccggtaa ttacggaagt tgagctagct tacgaagtag
    75001 cggaatgccc aattattggg attacaggaa cgaacggaaa aacaacgaca acaacgatga
    75061 caggactact actgaatgca ggagcagatc aaggaattgc acgtttagcg ggtaatattg
    75121 ggtatccagc aagtggtgta gcgcaagaag caaaatcaga agataaaatt gtgatggaat
    75181 tgtctagctt ccaactcatg ggaatcacag atttccgccc tcatatagcg gtgattacca
    75241 atatctatga agcacatatt gattatcatg gtacaagaaa agaatatgtc aaagctaaat
    75301 ggaaccttca aaaaaacatg acagaaaaag attatctgat ccttaactgg aatcagtcag
    75361 aactacaaga attagcgcaa agaacaaaag cacgcgtact gcctttctcg acaaaagaag
    75421 tgttggaaga cggtgtgtat gctgacgatt actcaatata ctataaaaaa gaaaaaataa
    75481 tggaaatatc tgaacttggc gtaccaggta agcataatgt agaaaatgca ctagctgcta
    75541 tttctgtagc aaaattgtat ggtatatcaa atgaagctat acgagaaacg ttgcattttt
    75601 tccatggcgt accacatcgt acgcaatatg taggagaaat ccaaggcaga aaattttata
    75661 atgattcaaa agcaaccaat attttagcga ctaaaatggc tctaagtgga tttgaaacgt
    75721 ctaaggtcgt gttattggct ggcggattag acagaggaaa tacatttgat gaattaattc
    75781 cttcattaaa aggaatcaaa gcaatggtcg tatttggcca aacaaaagaa aagttgatgg
    75841 atgctggaaa aaaagcaggc atcgagacaa tagtaacagc cgattctgta gaacaagcag
    75901 ttcctttagc attagaaaac agtacagatg gtgatgtagt tttattatca ccagcgaatg
    75961 ccagctggga tcaataccca aattttgaaa ctagaggaaa cagattcatg gaagctgtga
    76021 accgattaaa atagaaaaag tagaagcgag cgataaaaaa tgaaaatttt ggttacaggc
    76081 ggaggaacag ggggacatat ttatccagct cttgcctttg tcaattatgt aaagactcaa
    76141 gaaccgaatg ctgaattcat gtatgtggga gcaaaacgag gtctagaaaa caaaatcgtc
    76201 cctgatacag gaatgccttt ccataccttg gagattcaag gatttaaacg aaaaatttcc
    76261 atgcataaca tcaagacggt ccgattgttt cttaagagta tccgtcaagc aaaaaaaatc
    76321 ctcagtgatt ttcaaccaga tatcgttatc ggtactggag gatatgtttc cggagcggta
    76381 gtgtacgctg cagccaaaat gggtattcca acagttatcc atgaacaaaa cagtgtacca
    76441 ggtgttacca ataaattttt aagccgatat gtggatcgga tcgctctttc atttaaagat
    76501 gcggcttcct tttttcctga aaacaaagca gttcttgtag gtaatcctcg agcacaagaa
    76561 gtagcagata ctaaaaaatc agatattttg aaaacatttg atttggatcc agaaaagaaa
    76621 acagtcttga tttttggcgg tagtcaagga gcacttaaaa tcaatcaagc agtatcagtt
    76681 tttttaagtg aatatattcc ttcttcttac caagttttgt atgcttcagg agatagatat
    76741 tatgaagaga tcctaaataa aataaatcct gaaatacaaa atattagtgt ccagccttat
    76801 atcaaaaata tggcagaggt catggcttcc agtgatctgc tggtggggcg tgctggtgca
    76861 acttcgatcg cagaattcac agctctgggg ttaccggcag tgttggttcc cagcccatat
    76921 gttacgaatg atcatcagac taaaaatgca atgagtcttg ttcacgcagg agcagcaaaa
    76981 atgattgcag ataatgaact aacaggtgaa tcactaagtc agacagtcaa cgaaatcatg
    77041 ggtgatgaag aattgcaaaa gcaaatgtgc cgagcttcta aagaacaagg aatccctgat
    77101 gcttcaaaac gtctttatga cttagtaaaa caaataatca aaaaataaag gcggtggtct
    77161 tagtgagtaa gaaaaaagaa ccaaaaaaat tgtctcatcc gtcttctgat gaaaacaatt
    77221 tgactccttg gcaaaaggct aaccgaaaat atctggcaga acaagagatg aaaaaccaag
    77281 agccaaaaaa agaagacata acattagata cacccctttc agattctgaa gaagaaaaaa
    77341 cggttcaaga ggaacagcaa gaagaaagcc agtccgagaa aaaaatcgaa ttttttgaag
    77401 agatcaagca aaagaaaaac ggtggaccat ataacggttc ttttttgaac cggctgccca
    77461 atttaaaaag tcaacggcac aaagtactat ttcgtcggtt agctttgatc atcactgtat
    77521 tgggtatacc gctgattttt ttgatctatt atgtttctcc ttatagcaaa ttacaagcag
    77581 ttgcagtatc aggcaataag acagtcaaca gccaagaaat catctctgat acaaaattgt
    77641 cattaggaga aaatgtttgg ggacagtatt ttcatcgatc tacttatatc gatcgcctta
    77701 aaaaagcaca gccaagaatc gaaacagcaa atatacattt caaagggatg aatgaattcg
    77761 atttggatgt aacagaatat aaagagattg ctttgatcgc aaaaaacaat caatactacc
    77821 cagtgattga aaatggaaca gtattagatg aaaaagtagc aaatcctaca aaaaatctcc
    77881 ctatcttgga agagttcaaa gactctgcaa aaatcaaaga attaacaaag caatacaatc
    77941 agttatcatc agaattacaa aaagcaattt ctgaaatcaa gtacacgcca agagcaagca
    78001 ataaaaatct gatccaattg aatatgaatg acggcaatca agttattgta aatatcaata
    78061 atcttgcgaa ccaaatgaaa tattattcgc aagtagccaa agatatggat gaaaaaggtg
    78121 tgatcgacat ggaagttggt atcttctcgc atccttacgg tagcactcaa gaaacggaag
    78181 aatcgggcca atcggaagaa acaactgaaa gtgaagaaaa tgcggatcaa acaaacgaat
    78241 caagtgaaga ggcagaaacg caaaaagcac aaacacctgg atcgtctagc acaaacggat
    78301 catctgattc aaatgattca agtgaaacaa gtcaaataga agataatcca agtacaactc
    78361 cgtcaagttt aaatgaaaat tgataaaaca actttaaaaa gtaagaatgt actttctaaa
    78421 aaccagtaat ttatggtaga attggaagca gtgaatatat ctattaataa gtatatttta
    78481 aaacggacgc tagttgttcg cttgtatatg gaatagtaag taggagggaa tcccattcat
    78541 ggcaaaaaca ggaatgtatg taggccttga tattggaacg acatctgtta aagttgtcgt
    78601 ggctgaatat atcgacagcc aaatgaatat tattggagta ggaaacgcaa aatcagaagg
    78661 gattaaccga ggcattatcg ttgatatcga taaaacggtc caagcgatac aacgagcagt
    78721 acgacaagca gaagaaaaag caggtatcca gatcaaaggc gtaagtgtcg gtttgccagc
    78781 aaacatgctt gaagtagaaa attgccaggg aatgattgca gttaacggag attcaaagga
    78841 aatcaccgat gaagatgtca gaaatgtggc ttcagctgcc cttgttcgtt caatacctcc
    78901 tgaacgtcaa atcgtgtcaa tattgccaca agattttact gtcgatgggt tcgagggaat
    78961 caaagatcct cgtggaatga tcggcgtaag attagaaatg tacggtctgt tgtttacagg
    79021 acctaaaacg atcatccata acatacgtaa atgcgtggaa aatgccggat taatcgtcaa
    79081 cgaaatggtg attactcctt tagcgctgac tgaatcaatt ctttctgacg gagaaaaaga
    79141 ttttggtacg atcgtcattg atatgggtgg cggccaaaca acaacggctg ttatgcatga
    79201 taagcaattg aagtttacca atcttgacca agaaggtggc gaatttgtca ctaaagatat
    79261 ctctattgta ttaaatacgt catttaacaa tgcagaagcg ttgaaaataa actacgggga
    79321 tgcataccca gaacggacat caccagatga agaatttcca gtagatgtga ttggtcagtc
    79381 agaaccagtg aaagtcgatg aacgctactt gtcagaaatt atttcagctc gaatggaaca
    79441 gattttcaac aaagcaaaag atgcattgga ccaaatcgaa gcattagagt tgccaggtgg
    79501 cgtcgtattg acaggcggag ctgctagtct tcctggtgtt gtggacttgg cacaagaaat
    79561 cttcggcgta aatgtaaaat tgtatgttcc aaatcacatg gggctgagaa acccggtatt
    79621 tacaaatgta ataagtatcg tggattattc agcaaacttg agtgaagtgt atcaattggc
    79681 aaaaattgct gttacgggtg aaacctcagc agctcgtcaa atggtagttg aacaagaaac
    79741 aacaaacaca tatgagagct atgaagcacc tgaagaaaca atctacgatg agccggaacc
    79801 aaaagagtcc ggagaaaatg taaaaaataa aatcaagggt ttctttacaa atatttttga
    79861 ttaattcatc ctgggaggaa taagatatgg aattctcaat tgataataat atcaatgacg
    79921 gcgcagtaat caaagtcatc ggagtcggtg gtggcggtgg aaatgctgta aaccgaatga
    79981 ttgaagaaaa cgttaaaggt gttgaattca ttacagccaa cacagacgtg caagcattaa
    80041 aaaattcaaa agctgaaaca gttatccaat taggccccaa atatactcgt ggtttaggtg
    80101 ctggttctca gccagaagtt ggacaaaaag cggcagaaga aagtgaacaa tccttacgcg
    80161 aagctttaga cggtgcagat atgattttca tcactgcagg aatgggtgga ggaaccggta
    80221 caggtgctgc accaatcgtt gcaggtatcg cgaaagaatt gggcgcattg actgttggtg
    80281 tcgtgacacg tccattcact tttgaaggac cgaaacgtgg ccgttttgct gcagaaggta
    80341 tcgctcgttt gaaagaaaat gtggatacat tattaattat ctcaaataac cgtttattag
    80401 aagttgtaga taaaaagaca ccgatgcttg aagctttccg tgaagcagat aatgttttac
    80461 gacaaggtgt acaaggtatc tctgatttga tcacagcgcc aggttacgtt aaccttgact
    80521 ttgctgacgt gaaaacagtg atggaaaacc aaggtacagc attgatgggg atcggtgtgg
    80581 ctagtggaga agatcgcgta gtagaagcaa cgaaaaaagc aatctcctct ccattgcttg
    80641 aaacatctat tgatggagct gaacaagtac ttcttaacat cacaggcggt ttggatatga
    80701 cattgttcga agcacaagat gcttcagata tcgtagcaaa tgcagcaact ggcgatgtaa
    80761 atatcattct aggtacatct atcaatgaag aaatgggcga tgaaatccgt gtgacggtca
    80821 tcgcaacagg tatcgatgaa tcaaaaaagg aacgcaagtc tagccgacca gctagacaag
    80881 cacaaatgca atcacctgct caaaagactg tattagatat ggatcaagct aaaccaactt
    80941 cttcagaaga agaaaacagt tttggcgatt gggatatcag acgtgaacaa aatgttcgtc
    81001 ctagagttga tgattccaat tttgacaata tcgaaaaaaa agaatttgat acattcaacc
    81061 gcgaagaaac aaaatctcat ggcgatgatg aattaaatac gccaccgttt ttccgtcgta
    81121 aaaaataaag gagaggaaga gcacatgatt gctgacaact tgcagaaaat caagcaagaa
    81181 attcaggatt cgtgtgctct tgttcatcgt gatccgaaag aagttacatt agtagctgta
    81241 acaaaatctg ttgaatccgc tcaagctgaa gaattggtta gagctggcgt tatgaattgt
    81301 gcagaaaacc gagtagataa attattagaa aagaaacaag atttatttga ttttcctgaa
    81361 ataaagtggc atttaattgg taatttacag cgcagaaagg taaaattgat tgtaaatgaa
    81421 attgattact ttcatgcgtt ggacagttta agattagcag aagaaatcca gaagcggtta
    81481 gagaaagaat tatcctgttt tattgaagta aatgtttctg gtgaggaatc aaaacatgga
    81541 atttcaccag atgagctttt accgtttgtg gaatctttag ctgcctgcac aaaaatcaag
    81601 gttgttgggt tgatgactat ggcgcctaaa gaagcttctg atgagcaaat ccataaagtg
    81661 tttggtacgc tgaaagaatt gcgtgatctt gttcaagcaa aaggttatgc ccatgcacca
    81721 tgtagtgaat taagtatggg gatgagtcaa gactttcaaa ttgcgattga agaaggtgca
    81781 acatttatcc gtgtaggaac agcgctattc aaagacgaat aaaggaggaa caaaaatgcc
    81841 gcttttaaac agaggagcaa ttgctaattt tttcggatta gctgatgagg aagagtacga
    81901 ataccaagat tatcctgaaa caacaaaaaa ggctgtacag ccaactaaaa aaaatacaac
    81961 acagaatcaa tcaactcatt ctgtatctgc tgcgaatact catgaaaaac aaaaaacggc
    82021 gacttcacgt cctgtaacgc atgaaagtat tcagccggct gaaaagaaaa aagtaattga
    82081 actacatcaa tcacctacaa aaactgtagc gaaagaaaga acagcttcaa gaacctctac
    82141 acaacctaaa gcaaatcttg ctggaaaaat cactgtaatg gaaccaagag cttattctga
    82201 agctatggcg attgctaaac gaatcattgc tggagaagca accttagtga attttcattt
    82261 agtagaagaa aaacaagcga gaagaatcgt tgattttcta acaggaacag tttatgcact
    82321 agatggagat atcaaacgtg ttggagatga gatttttctt tgtacaccga ctgggatgga
    82381 gattgacagt tcaaccgctc aatcttttgc agatgcgaat ttgtttgatc tgtaagagga
    82441 ggaactacga tttatactat tgcactatta cttcatttac ttcaacgggc agcctatttc
    82501 tatagcatta tcttgatggt atatgcattg ctctcttggt ttccaggcgg gtatcaatca
    82561 gggctaggac gattattagc taagatctgc gaaccgtata tcagtttgtt cgatcgtctg
    82621 cctttgagga ttggaccctt ggatttcaca attttagggg caatcctgat cttgaactta
    82681 gccgtacaag gtttagcaca gatcgttata tggataactg tccatttagt ttattgattg
    82741 aagcaacaaa atctttattc tcagaataga taggagggga aaattttgga tgcaaatgta
    82801 taccagcact ttcgggcaga tgaacgtaca tttatcgatt cggtaggcga ttggattgaa
    82861 caggttcaag gacaatatgc accctatctg accgaatttc ttgacccaag acaatcctat
    82921 attttagaaa cactgattcg acaaagcagt gatttgcgtt tcatgtttta tggcggatat
    82981 gaacaggcag aaagaaaaag atgtttgatt ttccccgatt attacgaacc tgtagaggaa
    83041 gattttgaaa cagcattgta tgaaatccat tatcctagca aatttgccag cctaagtcat
    83101 gggaaaatcc ttggaacttt agtgggaacg gggatcaaac gctcttactt tggcgatatc
    83161 atctcggacg gtgatcgctg gcaagtattt attgcaaatg aggtggatca ttttgttgct
    83221 gcacaagtaa caaagattgg aaaggttgct gtacgcttgg aaccaatcaa atacacagaa
    83281 atgattatgc cgaaagatag ctggacacaa gaaagaggaa cagttagttc catgcgacta
    83341 gacagtgtga tctctgagat ttataatatt tccagacagc ggtccaagca gctgatcgaa
    83401 gctggtaaag taaaagtgaa ctggacagaa aatacaagac ctgattttgt acttgaacta
    83461 ttagatatta tttcagtcag aggttatggc agagtccaga tccaagaact tgaggggaag
    83521 acgaaaaaag aaaagtacag ggtactgttc ggtgtattac gtaaataaaa taaaaaggtg
    83581 gtttactcat ggctttaact ccattagata tccaaaataa gacattcccg acaaaaatgc
    83641 ggggatataa tcaagacgaa gtagatgatt tcttagattt agttgttcgt gactatgagg
    83701 aattgactca aagaaatcga gaattagaaa aagcagtcaa acattctgaa gaaaaacttg
    83761 agtacttcaa tgaattaaaa gatgctttga accaatcaat catcgtagct caagatacgg
    83821 ctgataaagt aaaaacaagt gcaagcaagg aatccgaagt gatcgttact tctgcacaaa
    83881 acaaagcaga tgagttagtt gcgaacgctg aaaaacgtgc acatcaatta acaactgatg
    83941 cagaagaaaa agcaagaaaa atcttgacag atgcaacaga aaaagcaaga cagcttgcga
    84001 cagaaactga agatcttaag aaaaaaacac gagtattcca tcaacgtatc agcttgatgc
    84061 ttgagtctca attagaacaa gtgaaaagtc cggaatggga tgaaatttta caaccattct
    84121 ccagctacgt gactgacagc catgaagtga tcaaagaagt tttagcaaaa cagcttgaca
    84181 atgaaaatga tactgatgta aactcagaca caggagtcat agaagcacct atgacggcat
    84241 ttgatacaca ggctattgat atctcgatcg tgcctggtga aaatgaaaac gagtagaaca
    84301 gaaaagcact ttgttattct taaagcgagc cgatgagagt ggaagttcgg taagacactg
    84361 catggtgaaa gatcctctac ttgagacctg cttttccgaa attagagtaa gaagcagcgg
    84421 ctgacctcgt tattggtcac agagagtttg cactagatag atgcaactaa atttgggtgg
    84481 taccacggca tgttcgtccc ttgcggctga acatgctttt ttgtgtccgg aaaacaaata
    84541 aaggagtgta tggttgaatg aaaatgaaag aaaccttgca attaggaaaa acaaaattcc
    84601 ctatgcgtgg taatttgcca aaccgagaag gcgagtggca aaaagaatgg gaagaaaatc
    84661 gaatctacca aaaaagacaa gagttgaacg aaggaaaacc tagctttgtt cttcatgatg
    84721 gacctccata tgccaatggt aatatccatt taggacattc attgaataaa atcagtaaag
    84781 acattatcat tcgttcaaaa tcaatgtctg gctatcgtgc accatatgtt ccaggatggg
    84841 atacacatgg attgccgatt gaacaagtat tggctaataa aggcgtgaaa cgtaaagaaa
    84901 tgtccatggc agaatacttg gaaaaatgtc gtgaatatgc actttcccaa gtagataagc
    84961 aacgagcaga tttcaaacgc ctaggagttg caggagattg ggaacatcct tatgttacat
    85021 tagatccttc ttatgaagct gcacaagtac gcgtatttgg taaaatggct gaaaaaggct
    85081 atatttacaa aggattgaaa ccaatttact ggtctccgtc aagtgagtct tctttagcgg
    85141 aagctgaaat tgaatataaa gatgtaaaat ctccatctat ttttgtagct ttcaatgtca
    85201 aagacggcaa agatattctt gatgaagata cagcttttgt catttggacg acaacaccat
    85261 ggacattgcc agcaaaccaa ggtattgctg taaatccaaa atttacgtat gtattggtgg
    85321 aagccgatgg ccgtaagttt gtcgtagcga aagatttgct agaaacagtc caatcagaaa
    85381 tcggttggga aaatgtaaca gttctaaaag aatttgctgg acaagaaatg gaatatatga
    85441 ctgcaagtca tccattctat gaacgtgaat cacttgtgat tttaggcgat catgttactt
    85501 tagacgctgg tactggatta gtccatactg ctccaggaca tggggaagat gactatatcg
    85561 ctggtagcaa atataaacta tctgtagtgt cacctgtaga ctcaaaagga ttgtttacag
    85621 aagaagcacc tggatttgaa ggtatctttt atgacaaagc aaatcctatg atcactgatc
    85681 tattaaaaga aaaaggagct ttgctgaagc tagatttctt tactcatagt tatcctcacg
    85741 attggcggac gaaaaagcct gtgatctatc gggcaactcc acaatggttt gcatctatcg
    85801 ataaattccg tcagaatatt ttggatgaag tagaaaaagt agagtgggtt atcccatggg
    85861 gtaaaacacg tttgtataat atgatccgtg accgcggcga ttgggtaatt tcccgtcagc
    85921 gtgcatgggg agtaccactt ccgattttct atgctgaaaa tggagaagca atcatcacac
    85981 cagaaacaat cgaacatgtg gcaaaattat ttgctgaaca tggatcaatt atctggtttg
    86041 aaaaagaagc gaaagaactt cttcctgaag gatttaccca cccaggttct cctaatggcg
    86101 aatttacaaa agaaaaagat atcatggatg tctggtttga ttctggttct tctcatgaag
    86161 ctgttttacg tcagcgacca gaattatcat tcccagcaga tatgtattta gaaggatcag
    86221 accaatatcg tggctggttc aactcaagta tcacgactag tgtggctatc aatggtgtag
    86281 caccatacaa atcagttatt tctcaaggat ttgctttaga tggtgaaggc cgtaagatga
    86341 gtaaatcttt aggaaacatc attgcaccag aaaaagtgat caaacaattt ggtgcagata
    86401 tccttcgctt atgggtatct agtgtagatt atgaagcaga tgttcgtgtt tctatggata
    86461 tcttaagtca agtggcagaa gtatatcgta aaatcagaaa tacgatgcgt ttcttattag
    86521 cgaatacaga agatttcgat cctaaaaaag atactgtttc gtacaatgat ttacgttctg
    86581 tagacaaata tatgaccgtt cgattgaacc aagtaatcaa agaaatccga gaagaagggt
    86641 acgacaaata taacttcatg catatttacc gtacagttat gaacttcttg acggttgatc
    86701 tatcgtcatt ctacctggat tttgctaaag atgtagttta tattgaagca gaagatgatt
    86761 atcaacgtcg ttgcatgcaa actgttttct atcaaacagc tgtagctttg acaaaattat
    86821 tgactcctat cattccgcat acagcagaag aaatctggtc attcctgaaa gaagaagagg
    86881 agtacgttca gttaagcgag tttcctggtt atgaagagtt tgcaaaccaa gaagaattga
    86941 tggatacctg gactgctttc atggacttcc gtgataatgt cttaaaagca ttggaagaag
    87001 caagaaacag caaattgatt ggtaaatctt tggaagcaaa actaactgtt tatccaaaac
    87061 aacaagttcg tgaaatgtta aaagctttgg atgcagatat tgcacaatta ttgatcgttt
    87121 caccagacta ctttgaagtt atggcagcag atgaacaagt gccagataac gctatggtat
    87181 ttgatgatgt tgctattaca gtggaaaaag cagacgggga aacttgcgat cgctgtcgcc
    87241 aagttcgtaa agatgtagga gtagatgaaa aacttcctca tctatgcggt cgttgtgcaa
    87301 aaatcgttga agacttctat cctgaagctg tagctgaagg attcgaagaa aagtaaaagg
    87361 gaaaaggggg tgtgacatgt tctttgtcac accccctttt gttatcaatc gtttaatttt
    87421 ccacgttcac gataccagtt atctggttgc cagatccatt cgaatccgtc tttttcaagt
    87481 agttcgaaag ctgctttagg tcccattgat ccagctttgt agttgggaaa atccggttgt
    87541 gtttggtccc aagcttttcg aatgacatcc acgatatgcc aagattgagc gacttcttcc
    87601 caatgagaga agttcgttcc atcaccattc aacgcatcta atagtaattt ttcgtaagct
    87661 tctgggctat tttcaaccat ttctgcacta tttctaaatt ccaatttgat tggttccgtt
    87721 tcaaatcctt gccctacttc tttcccattc aaggataaag aaaatccttc agttggctga
    87781 atatagatcg ttagaacatt aggtggaagt gtcgtatcgt cacatggttc atcgacagat
    87841 gttttgaata cattaacagg aacttgtttg aatacgatgt tgatccgagt ccctttttca
    87901 gtcaaacgtt tgcctgtacg tacatagaaa ggaacacctg accaacggaa gttatcgata
    87961 gtgaatttgc ctgcgacgaa tgtttcagtc tctgattgag catccacttt gtcttcttcg
    88021 cgatagccct tgaattgtac accatccaat tcaccttgag catattgccc gcgaacgaag
    88081 ttttctaaca cttcttcttc gttataaatg cggatagctt tcaatgcttt gatcttttct
    88141 gtacggattt ctttttcgga aaatgctact ggcggttcca ttgcaagtaa tgctacaacc
    88201 tgtaaaatat gattttgcac catgtcttta agtgcgccac tatgatcgta gtagcccccg
    88261 cgatcttcta caccgaggtt ttcgccaaaa gtaatttgga tattgtcgat atagcgattg
    88321 ttccattgag cctcaaaaat attattggca aaacggatag ctgagatgtt ttggatcatt
    88381 tcttttccta aataatgatc aatcctgaaa atatcttgtt ctgggaatac ttctctgatt
    88441 tgctggttca attcaaaagc agactggtaa tcagaaccga acggtttttc tatgatcaaa
    88501 cgattgaagc cattttttgt cataatattt tgtgatttca aatgagaaac gatcgttcca
    88561 aaaaattgag gtgccatagc caaataatag acacggttac cgtttaattg atagtgtcca
    88621 tctaatcggt cagacaattc ttttaatgtc tgataatgcg ttgaatcatt tacatcatgg
    88681 gattgatagt aaaaatggct tgcaaaggta gttgcttctt catctgaagg attcaatgca
    88741 cggattgttt ctttgacaac ttcacggtag tgctcatcgc tccagggacg gcgagcggtt
    88801 ccgattacag caaaatgctc gcctaaattt ccttttctgt aaaggcggaa caaagacggg
    88861 tacaatttac gctgggctag gtcacctgta ccgccgaata tcgtaaacaa tacatttttt
    88921 tcattagaca tgtggataca ctcctttata ttttatcgac aaaaatcgtg ctggccgcct
    88981 taaagctgac ggggattttc tttctatcat tttggatagt gatcggtcct tcataagctg
    89041 cgatgtcaac gatctcatat tcttcgttga tattcaggtc aatagtgact aagtaatcca
    89101 acaattcttt ttcatcaagc actcgtgcga tacgcacttt tgtaccgaca ggataggact
    89161 ccaatgtttg tcggcgttct tcatggacaa cttcctcttt tttaggaatc gatcctccat
    89221 gaggacaatg ttcaggatga ttcaaatagt tttctaaatg atctgcaaga tgttccgaag
    89281 tcacatgttc caatacttca gcatcatcat ggacttcatt ccagctatag tctaaatgtt
    89341 caactaaaaa aacttcccat aagcgatgtt tgcgaatcag actgctagct ttttgcagtc
    89401 cgcttgcagt caattgtaca ccttgataag gggaatgttc tacaagctct tctttcacaa
    89461 gtttagaaat catttcactg acagatgcag ctgagacatc tagactagat acgatttgtt
    89521 tattgttgac tttcgttgta tctccaccta gttctaaaat gattttcaaa taatcttctc
    89581 gatttggtgt catattcgat catcctttca tggtaaaaaa ccatcattag taagtgtaac
    89641 aaaaaaaacg ttaattgact atttttctaa ataaaaaaca aaggattttt agacgttttt
    89701 acaacaaaaa acgaaagatg atagagaaga ctcattcttt cgtttataaa ggatatatat
    89761 atacattggg agggatctat ttttcagata acaacttata tgaagtgtct gcagattcgt
    89821 cataaagagt ttgttcggga taagaaaaga taagataaaa accatactga tcacgtacga
    89881 ctaaacgata ttcatctatt tctaccacag atgtgccaag agactgaccg ttgatcaaaa
    89941 acgtgtaatc agatgtaatc tgtaattgtt gtttttgctg gctatcacta aagaaccatg
    90001 taccttgata ctttgagagt ccttctgact tttccgcttg ttttttcttt ttcaagtaaa
    90061 taaaacttga gagaacggta atgagtgaac caagaaaata gatcattttt tttatcacca
    90121 aatcactcct ttatgagaaa ataatcgcat agacatattc tttcttcttt atttcattgt
    90181 accgaataaa agctaaaatt tctctaagac tttcgactgg tttttttact gtttttctac
    90241 aaattatgat aggatacata gtaggaagaa aggtgacata atttgaagta tcagcaagtg
    90301 gaaatagctt tttttattga ccgcccgaat cggtttatag cacattgtat gaaaaaagac
    90361 ggagaaataa ttattgcgca tgtcaaaaat acaggtagag gaaaagaggt cctgatacca
    90421 ggcgctgaag tggctattgt atttgctcct ggacctaaac ggaaaaccgc ctatgatctg
    90481 attgctgtaa aaaagaaggg tgactggttt aatatcgata gtcaattgcc taatcggctg
    90541 gcaattgatg gtattttaga cggcacgatc cttttaccag gattaactgg tccatttacg
    90601 gtatacaagc gtgaagtaac ttatcttcac tccaaatttg atatttattt agagacggtg
    90661 gtcggacaaa aagcatttgt tgaagtcaaa ggtatgacac ttgaaaataa agcgattggt
    90721 gcttttcctg atgcgcccac actcagagga ttgaaacata taggagaatt aacgtatgcc
    90781 gcacaagatg gttatgccgc ttatgtcttg tttattgctc agttcgaaca tcttcatctg
    90841 gcaacgatcc atgaagaaat gcaaccagca ctagctgata tggttcgaca tgcgcagcaa
    90901 agcggagttc aaatcctcgc ctataattgt caagtatcgg cagatgaggt aactgtcaag
    90961 caggccattc catttgatgt agatatccct tttgaagatc ctatacaata gaaagaaggt
    91021 aaaataatga tcaacttagg tattatcgga acaaattgga ttactcatca atttgtccaa
    91081 gcagctttaa gcacaaaaaa atatgaattg acagcggtat attctagaca tttggaaaaa
    91141 gcacaggaat ttggttctca ttatgaaggg gatatcgaat tcgcaacaga tttgaagact
    91201 tttttcaata ttactcatat ggacaccatt tatattgctt ctccgaatag tcttcacttt
    91261 agtcaagcta agcaagcaat tttggcagga aaaaatgtga tagttgaaaa gccagctttt
    91321 tcgacgccaa aagaaatgga tgaaatcatc catttggcaa atgaacacaa tgtgtatttt
    91381 tttgaagcag caagaaatat ccatgaatca ggttttaaaa agattgccga ttacttacca
    91441 ttaaaagacg agataatcgg tgcaaatttc agctatatga aatattcttc gcgctatgac
    91501 caagtattag atggagaaga accgaatatc ttctcgactc atttctcagg tggtgcattg
    91561 atggatttag gtgtttacct tgtatatgca gctgttgctt ggtttggaat gccaaaagaa
    91621 gtccattatt tcccaagaaa gatttctact ggtgtagatg gtcttggatg ggggatctta
    91681 cgttatgaga attttgatgt atcgatccag ccaggtaaaa tcggtgattc ttatttaccg
    91741 tcagagattt attttgactc aggaacgcta gtgatgaatg gagtcaatgc aattgaacaa
    91801 gcacaatttc atgatcgcgc gcataaagaa atcattgatt tggcggtaac agctgcagaa
    91861 aatccaatgg cagatgaagc agaggatttt gccaatgtca tggctcatcc gaaagatcca
    91921 gcttggggat tgttgtatga agagtggatc gagctagcta gaaatgtgaa ccaagtgatt
    91981 tatgatttaa gaaaaaatgg cggcatcaaa ttcgatgcag ataatgagga agatttttaa
    92041 tgaacgaatt tgtacaagta tttcccgaaa attggcagaa aaaatatgag gataaagggt
    92101 ttatctcacc ttctcttatt caacgagcag tttttcagcc actaagtaat aaacaaagta
    92161 tagtagcggt ttctcctaca ggttcaggta aaacactggc ttatctttgg cctctactac
    92221 taaacgtgga accaggtgaa gcaagtgcgt tggtcatttt tgcttcttct caagaactag
    92281 ctattcaagt agcagatgtt gcacgtgaat ggggaaaaga caaagagttg aaagtccaat
    92341 ctttggtggg cggagccaac gtcaaacgtc agattgaggg tttgaaggaa aaaccagaaa
    92401 tcttgattgg tacaccagga agaatattgg aattgatgaa agcaaaaaaa ataaaagcac
    92461 atcaagtgaa aacaatggta tttgatgaag cagaccagct atttgacgct gggaacagcc
    92521 aaatcattga tcaaattctt catcaagctc caacagagta tcagctagct tttttttcag
    92581 cgacagcaga tcgttccctt gaaagcattg aaaaaatcac tgggaaaacg tttgagacaa
    92641 ttgacgtgac agcagaggac gattctcgaa aaggactgag acattacttt ttacgtgtac
    92701 cgatacgaaa gaaagatgac tacttgagac gtctcacgca tatagaagat tttcatggtc
    92761 tgattttctt taatcaactg actgaattag gcgtaatgga agaaaaattg ctgtatagag
    92821 gtgtaccggt aggaagtctg gcctctgatc agaacaagct actccgaaaa gcagcgctag
    92881 aacaattcaa aaagaaaatg gtcagagcac ttttgaccac agatgtggcg gctagaggtt
    92941 tagatattac aggtcttcct tatgtagtga atgcagaagt tccgttaagt gaagaagctt
    93001 atttgcatcg ttcgggaaga actggtcgaa tgggtaatga aggaatagta attacactcg
    93061 tacaagataa taatctaaga gatttaaaac ggcttttacg tccatcaaat ataacacttg
    93121 aagagatttt tttatacgga ggtaagctgc aaactgagca gccaaccaaa gaagatgcag
    93181 ctcctgcagt aaataaaaag tatgcgaaaa ctttttctgg aaaggagcag aacccagaat
    93241 ataacaaaga aaaaataaga aaaaaagtta aaaataaatc aaaaaaagag agaaataaag
    93301 gagcaaggcg caaataagcg cctttttatg ctatgattat gaaaacggga acaaaattgg
    93361 ttgccagagg aggggttatg tgaaagaacg tcaagaagag atcttgcagc tattgacaga
    93421 aaaccaacaa ggattgacag caagtgatgt agctgagcgc ttaactatcg atcgaagcaa
    93481 tgcaagccga tatttaagtg aactatacaa ggcccatcat attgtaaaaa ccgctggccg
    93541 accagtcgtt tactctttgc caacggaaaa gtcaaaatct gatgaagtgc atgtcgactc
    93601 ttctacgcaa gtgacttttg aaacactcgt tggagaaaat gattctttaa aagtcagcat
    93661 acagcaggca aaagctgcga ttctttatcc accgcggggg ttgcatacga ttatttttgg
    93721 agaaactggt acagggaagt cgatgtttgc tgaatgtatg tatcattttg caatcgattc
    93781 agagatgctt tctgcagatg cgccatttgt ttctttcaat tgtgcggatt atgctcaaaa
    93841 tccgcaactg ctctttggac acatctttgg gatcaaaaaa ggggcttaca caggagcagc
    93901 tcaagatagt cccggtctaa tagccaaagc agacggcggt atattgtttt tagatgagat
    93961 ccaccgttta ccgccggaag ggcaggaaat gctgtttact ttcattgata aaggtattta
    94021 ccgtccgctt ggagaaagtg cacaagtaca tgaagcatct gttcagatca ttggggcgac
    94081 gactgaatct tcagaaagtt tcttatctac gttcaatcga cggattccta tggcaatcac
    94141 cttgccgaat cttgcttcac gttcactgga tgagcgttat gaaatcatct ctctttttat
    94201 caaacaagaa gcgaatcgtt tgaatcaacg tatcgatatc gaaaaagaag cgattcttgc
    94261 cttcatgctt tatgatgcgg aaggaaatat cggtcaagtg aaacgagact tgaaactagt
    94321 ctgtgcaaaa tcttttttac attaccgtac tcatcatgag aaaaagctaa tcattcgaaa
    94381 agaagaactt tcccttcaag tacaaaaagg attactgaaa atcaaggaaa taccggaacg
    94441 tctcgaccga ttcatggaca gcaaaagtca gtatttgaca tttgaaccag gatttgctga
    94501 tgttgtctgg tcacaagatc cagaacgaaa catgcaggtc tataacgata ttgaggaaaa
    94561 agtcacttct ctttccgaaa ccggtgtgga gaacattgat ctagagaccc tcatttcaaa
    94621 agatgtggat gcttatttcc agacatatgt caaagaattg actaaaagtt cgattcccaa
    94681 agatcttttg ccagatgaaa tctggcggtt aaccaatcaa ttgtatgatg tggctgaaaa
    94741 acggttagac cgtatttata atgaaaaagc tcgttttgct tttgctttgc atctgcaaag
    94801 tacattggat cgtgtgagag aaggtcatat gatcgtccac ccagatttga ataacgtacg
    94861 gaaaaatttt aagagggaat tccaggtagc aatcgatctt tcaacgatca ttgaagaaga
    94921 agaacaagtt gagattcctt ttgatgaaat cggctttatt agtatgtttc tttctatcaa
    94981 tctaggagaa agtgagcctg ttaaagaaaa caaagtagat gttctcatat tgatgcacgg
    95041 cagacagact gcttcaagca tgttggagat ggcacaagaa ctattaggaa caaaagtagg
    95101 gaaagctttt aatatgccac tggttatgga agttcaaaca atgtatgaag aagtgttaca
    95161 atatgtcaaa aactatcaag agcatttgac gaatggccta ctcttgttaa cagatatggg
    95221 atcattaaac accttcagtg atttgattta tgaagagact ggcattcgga cgaaagctat
    95281 cacgatgaca agtaccatga ttgtgataga agcgatacgg atggcaagtg ttggaagaag
    95341 cttagaagat atttatcaaa atatccagct ttcctttgaa tcgatcgtac gtgatcagtt
    95401 caaagcggaa aagtctgaaa ctttacagcg taaaaaagcc gtaatcgtga catgctttac
    95461 tggtgaagga gtagctgcca aattatatca gcgtattatg ccagtgatta atcaaaataa
    95521 ggtagaactg atccagatgc agtttttaga acgtgaatca ttcaaaaaac acatcgatgc
    95581 cttattggaa gaatatgaga tcaaagcaat tgcgggaaca gttgatgttg attatcaaaa
    95641 tatcccattt ttttcagcct atgacgtttt tgatgatgaa aaactaaata ttttaaagcg
    95701 tatagctgat gatgagatcc cgacagctaa aattgtcgat tcacttgctg gatcattaag
    95761 cgatgtcttt tctattgatg aactgatccg ttcattgcaa aagacagttc agcagatcca
    95821 gaccgatttg tcgattatcg tggaacctgg agtagatact ggaatcgtta tccatttagc
    95881 cttcatgtta gacggattga tcaaacaaga aagccatcgg caatttgaga aactgtctat
    95941 tttctcaaaa atttatcgtt tggaaatgga tatcgttcgg gcaaacttga tggcactaga
    96001 acgaaaatat caggtaaaaa ttccagaaga tgatatcgca tttcttacac aaatgtttct
    96061 tgaaaataaa ataaaaaaat gaacacacta atcatactgt ttacacacta aacatctgtg
    96121 tgcgcactat aaaaaagagc taaaaagcat gaaaacgcta tttcagctct tttttttatt
    96181 ggcatgcttc ttgcgttata taaaagtgta aaaaaataaa aggagtgtta aaaatggcaa
    96241 aaaaaacaat catgttagtt tgttcagcag ggatgagtac gagtttattg gtcacaaaaa
    96301 tgcaaaaagc agcagaagaa aaagggatgg aagccgatat ttttgcggtc tctgcctcag
    96361 atgcagataa taatttagaa tctaagaatg tcgatgtatt attattaggt cctcaagtac
    96421 gtttcatgaa agctcaattt gaacaaaaac ttgcgcctaa aggtattcca ttagatgtca
    96481 tcaatatgca agactatggc atgatgaacg gagaaaaagt tcttgcacaa gcagaaaatc
    96541 taatgaaata aatcaagtat gcagttgggg gtataacaac gtggaagatc aacaaaatct
    96601 agaagccatc atggggttaa tcatgtttgg cggtaatgca aagagcgatg caatggaagc
    96661 gattgcggct gctaaaatcg gtgattttga gttagcggat aggaaaatcg ctgatgcaga
    96721 agaatcactt atacaagcgc atcatgcaca aacagacatg ttgacacaag aagcacaagg
    96781 aaatcatatg caagtgacat tattgactgt tcacagtcaa gatcacttaa tgacatctat
    96841 tgcgtttact gatttagcaa aagaaatcat cgaactttat cgtcgcgtat acagcgaata
    96901 aatacaactt cttttttgaa cggaagaaga aaaatttttg aacggatttt ttattttgtt
    96961 ataaggagaa ctctctttat ataaaaaact tataggagga agtaaaaaat gaacggacta
    97021 tcaagttgga tggagaaata catcctgccg gttgccgcaa aaatcggagc gcaaaaacat
    97081 ttagttgctt tgcgtgatgc ttttatcggc acactgcccg caacaatggc gggatcagtc
    97141 gctgtaatga tcaatgcaat tattcgtgat ttaccgcaac agtttaacag tacctatgct
    97201 gacagtttag cagcagacaa aggaatcttt gccgtattga atgtcatcat cggaatcaat
    97261 ggttttgtct ggaacggtac actagcaatc gccggattga tctttgcctt ttcttggggg
    97321 tataatcttg cccgagctta tggagtaaat gatctagctg gggggatcgt tggtttagct
    97381 accttgattc aaggtatttc ctttggtcca gcattatcag cagcattaga tgtgaatgtt
    97441 ccttcaaatg tcgcagatgc aatcaatagt tctgagattg gtgcaacgat tgcagatggc
    97501 acactgtcag ttggattatg gggttggcta aaactagatc atttgaatgg aaacgcttat
    97561 tttacagtta tgatcatggg agctatttca gtcattattt tttgtaaatt gatgcttgcc
    97621 aacattacga tcaaaatgcc tgattcagta ccaccagcag tatctaaagc atttgcagcc
    97681 attttaccag cgacgatcgc tttatacgtc attgctatta tcaattatat cgtaggtcgt
    97741 gtagctgatg ggcaactgat cattgatttg gtgcaaaaat atattgcaga accattccta
    97801 ggattatctc aagggttggg agcagtattg atcgtcacag tatttgttca agtattctgg
    97861 ttctttggta ttcatggatc aaatgtattg gcaccagtgc tagagggaat ctggggacaa
    97921 gcacaactaa tcaatattga tattttccaa aaaggttata acggaaaaac tggtacacca
    97981 gccgtgttag atgcaatcga agatggaaaa gcttatatgt gggtccgcgg atcgttcgat
    98041 gcttttgcat ggtttggcgg atcaggcgga acgatcgtct tactgatagc tatcttgatt
    98101 ttctctaaac gtgcagatta tctaacagta gctaaattat ccattgggcc tggtatcttc
    98161 aatatcaacg aaccagtgat gtttggtctg ccaatcgtat tgaatgcaat catgtttatc
    98221 ccattcttga ttgctccagt agtagcaaca gcaattggat ggacagctac ttatcttggc
    98281 ctagtcgctc cggtatcgca gcaagtcaca tgggtagtac cgccgttctt attgtcattc
    98341 ttagcaacag gagcggattg gcgggcaccg atcgtaacat tagtatgtat ggtcgtgact
    98401 ttcttgattt gggcaccatt tgtcatctct gcaaacaaaa tggaccctgc cgcaggcgaa
    98461 caacaataag atgaacgtga ggagcgggac gctttaagtt tcgttcctca taatgaattt
    98521 tcgaggagga actgaaatga ttacaattgc cagtgcaatg caacaagatg aaatcaaaga
    98581 attgttagaa ggatacaatg aagaaggaat gacttttaca tttaaagaaa aacaaggaat
    98641 caagctgttc tttgaaacaa gtgcagaaga tccggaagtt gcggctaaaa aagcaaagga
    98701 actaatcaaa gcacagcctt ggggaacagt cctttatttt caatcaacag ctgtttagaa
    98761 aatggtttaa aaagatagga tggttgagat gataaaaaac ggtttatttt tatgtagtat
    98821 tggttctttg atcgtgttgt atagtttgaa tccacattcg caaaggtatg atttgtatag
    98881 tatggtcaca ggtctttttc taacaggatt aggaatctat ttcttcatga aggggaaaaa
    98941 aagagaagaa gcaaaggaga aaaataacta atggaaatca cgaaaaaatt aaatattcca
    99001 gcatcgtttt tttacgataa agttatggac tctgtccttt tcgatgtacg taaagcgacc
    99061 ggcaaatcag taactagaaa acagctgaaa aatttggagt acgtcaaaca attctcgcaa
    99121 aataaccggg ctcgcataaa aatcgaagaa gtcattgaaa accagtctta taagtttcgt
    99181 acatcgacaa cgaagaatga attcgtcgtt cattatcaaa tcaaaccatt ggacgattcg
    99241 acctgtgagg ttcattacac agaaaaaatg gagtcttatg gcatgcttca aaagttgaat
    99301 gatatgcttt taggaacaat cttgatgtat tttaaacgga gacgtttcaa aaaaatgcta
    99361 gatatgatcg aagcaacgta ttaaatcaat gaaacatggt actatttagt tattgaaaaa
    99421 tgaagtaagc tagaaggaat ttttcatagg aagatagatc tttcctgcga atcctcacta
    99481 gcttttttgt aggaaggggc agcaaaatga caaacaaagt aagagagcta ggtgtatctt
    99541 cgattgagga aatgtttgat ttagccactt atgcatttaa tggggcagat acacctgaaa
    99601 ggcgagaacg ttttcgtaca cttgcggaga attcttggaa ttacggattt tttgatgagg
    99661 aggatcggct aacaagtcaa gtcatggcga ccccttttcc agtgaatttt tacggacaag
    99721 agtacctaat ggccggcatt ggctatgttg cttcttatcc agaagcaagg ggacaaggcg
    99781 ggatcaatca gatcatggaa aagatccttg aagattgccg tgatcgtaaa gtaagcttat
    99841 cttatctggc gccattctcc tatcccttct atcggcgcta tggctatgaa caatcatttg
    99901 ataaaatcag ttatcaacta aacagtcgtg atgtgccgtt tatcaaaaaa aaatctggaa
    99961 aaataaagcg tatggatttt gaagatgcaa aagctgcaat cagaagaatt tatgaacaga
   100021 tgccggaaaa ccaacgagct ggtctgaagc gcgaagactg gtggtatacg tataaattca
   100081 agcaaaaagg caattaccag tttgctttgc attttgatga taatgaggaa gcaacgggat
   100141 atatcgttta tcagcttgca acgtcttcct ttattattgc ggagtgggga tttttggatc
   100201 atgatgcttt ttgcagcctt gttcgcttcg taagttctca caatggtgct tttgaaacat
   100261 ttgaatattc atgcggctac ggcggtaatg atcaaaatta tctattagaa aatccatttg
   100321 cttctgtaat gatcacacct tatatgatgg cgaggatcgt agatatttct ttgtttttgg
   100381 aaaattatcc atttaaaaag agacaagctg catttgccct acaaatagaa gaagatcatt
   100441 atgcgaaatg gaatgaagga atcgtggaag taacaatcga aaatggaaaa aatcatctct
   100501 caaaagtaga acaaacaaaa ctcccaatcg ttcgaggaag tatccaacat atcacgcagc
   100561 tattattagg gtatcgtaaa gtggaagagt tggtattcca agaaagaata caggtgacaa
   100621 aagaatatga agaaacgtta agctcaatct tgccacagca acagccaatt cttaatgact
   100681 atttttgata aaaaacgggt gatgacaata tttttgtcac cacccttttg tttttcattt
   100741 ggcatttgaa ggaaaatgtt aaagtaaatc ctcttttttc gtaaatttga attttttgtt
   100801 ttcttttgtt ttagggtttt cttttttgtg gtcttggatt gcttctttcg taatcttttc
   100861 ccgatttttt ttagatgaat ctaagcgttc tgcgtatact ttttcttttg gcttatcatt
   100921 cattggaaag gacctcccta cattatttca ttctacctct agtttatcat ctgttaagga
   100981 ctagtggaaa cgttttgcct aacttataag ctgatttttt tagcagataa gcttgcaagt
   101041 aaaaaacaaa caagctacaa ttgatttatt gaaattgttc ctgtagctca gtaggataga
   101101 gcaatcgcct cctaagcgat aggtcgctgg ttcaattcca gtcaggaacg tataaataac
   101161 ccctgtatcc tttgcggtac aggggtttgt tttgtatttg tgccaaaaat gtgccaaact
   101221 agttatcatt tttatataaa ctatcgaaca cagtattgat tttttcttta tcctgatctt
   101281 caagctctcg aacaatatga agataagtag acattgtagt ttctaaactg ctatgtccta
   101341 aacgtttcga tacgctaagt atatttactc cttgataaag taaaatagat gcatgtgtat
   101401 gccttagtcc atgcaaagta aattgctttt caatccctaa ttcttttaat tttttgcgca
   101461 aatatttgct gacggcgttt gatgaaacta atccattttt taagttgaaa aaaacaaaat
   101521 tatgagggtt tttgatttca aaattctcga ataattcttt ttgattgatt ttaaactttt
   101581 ttaagagatc aatcgtatgt ttatcaatgg aaattttcct atttgaagtt tcgttttttg
   101641 tttttcccca ttcatttaat ttataattcc atgttttatt aatagtgatg atttgatctt
   101701 cgaaatcgat atcttcccat gttaatccta gaagttcagc aaatcgcatt ccagtggcac
   101761 cagcaactaa cacgagcata ggagaagagt actgcgcaga aaggttttct tctacgagtt
   101821 tcattaaaga tttaaattga tcataatcta aatatttatc ttcttttggc ttcaatgaat
   101881 cttttccttt gattactgct tttctagttg gatcaaacgg aattaatcct tcttctacgg
   101941 catctttcaa cgacgctcta atatggttat taaacttaat aacggtagat tttacatggt
   102001 ctttagcata cttatttaaa aagcgttgat atcccactct atctaaatca gaaatcaata
   102061 ccgctggcat atatttcttt atgttcatta acgtatcttc gtattttcta taagtgatag
   102121 gagatactgt tccttcttta taaagttgca tccaatcctc aaagtaatct gataataata
   102181 gatttttgcg atccccttta aggcctttgt tcaagttata ttctaattcg ttggcggcat
   102241 cttttgcttc tccttttgtc ttaaatcctg attttcttat cttcgtgtat tttccgtcat
   102301 cttttttgta tgaaatttcg tattgccaac tatttccacg tttgactaat cttgccataa
   102361 ttgaatcagc tctctttctc tgatacaata ggaactataa agaagcccat tgtttgggtt
   102421 ttattatttt ttgcacatcc tttttgcttg ccggcgcaag gatgtgctat ttgtcgtttt
   102481 aatggtataa ttggatgtgt attagatcat ccaatcagag gtgtttatta tgattaaagt
   102541 gatttttaaa agaataactg aacttccaga gtttagatta tttgttgatt attggtatgt
   102601 ctggtttttt attgttgcat tgctgatagg tctagatgtc atattagaaa gaaaacttaa
   102661 gtaagagttg agttaataaa ttgaattcct aaatgagata ttttgtagcc catattttgt
   102721 ttgccgacat cacctaatac tatggagcta atcgtttttt ctaacagacc aaaatcagat
   102781 aatctattta agctaccatc tattagctct tgtgaatagc cagacatgct gatatttcca
   102841 gtgaaatttt cgtttccacg actcattaag catgctaaca attgaatctc aatcgatgtt
   102901 aattgattca gtacaagaag ataatactcc tcgttatccc atgaagcgtt gttaattcga
   102961 agtaaacaat tcttataaag atttttatac atatctattt tattttgtgc ctttgatttt
   103021 tctacctcgt catttatccc ttcgaatatt ccaatgagtt ggtccttgtt ctctaagttg
   103081 aaaacatctt ctggaatttg atcgcgaatg ttttctaatg attcgtttaa atttttgtag
   103141 aatttctcga tgcgtttgaa acgcttctcg tttttagacc caaaataaag tgactgcaca
   103201 acgccaccaa tataaggaat tgctccaata ccgccttcaa ctattaattc aagatattct
   103261 tttttggtta gtttttcatt gctattatcc atagttacct cctattttgt catttccttt
   103321 acaagcattg tgactcctga tggcactctt ttgtataggt tttattattg tgcacaatct
   103381 aactcttagt ggggcgtggt tcatttattt tttacttact ttactattaa tcatatccca
   103441 ttgagcatag gatttttcta tgttcgatcc tcttgaacta atttctcctg taaaagttac
   103501 tttatcgccc tttgtaaagg tatcagcatt gtttaagtcc ttcgcaaaaa ttacatatga
   103561 aactttaggt gttgcagaaa tatcattcca acttttatca tcgtactctt tgtctgctat
   103621 aatggctatt ctagtagtca ttgattcgat aacagttcct tcaaaagtat atgttttacc
   103681 actaatatat ttagtaaaag ctgtattttg ctcagtagct ggagtaatag aataataact
   103741 atctaagaaa gcaccccagt catgattatt tgtctctaaa aattcttcaa attgagttag
   103801 gcttttattg ctgctgttag atgtagtagt ttgagtatca gatgatgagc tttcctgttt
   103861 gttattgtca tttgcctcgt ttgatgagga aagcgagaaa cctacggtag taaaaataat
   103921 cccgataata aggagaatca taggtgtttt cttatttgtt tttttgataa atcttacaat
   103981 taacatgatt aaacctataa taaataaaac aataccagta aaaccaaata taccgtccat
   104041 taatagatcc tctttctctt ttgatattga atattataaa ccaagcaatt cttttttctt
   104101 aaaatcgaat tcttcttgat taataatccc ttcatctaac aactctttat actttttaat
   104161 ttcatctgca cttgaaattt gtgtttcttt ggaattatta tctaatatag attgttgctt
   104221 ctctatatat ttttttaaat tttccatttc attccaatat ttttttgtaa acataacggt
   104281 gttttcatct ttcgtggccg ctaatatacc tccgcgactt tcgtttccgc ctagcaaggt
   104341 aaattgtata taaccattac tcatacctgg tttttttaat tgtacggctg atatattttt
   104401 aaaggggata gttttttctc ctttaatacc ttgattaact aaatttataa atccttttct
   104461 aataattgaa atagaatcat cagttacttt aatcaaggtt tttcctggag attttattaa
   104521 aatctctttt tccatttttt cttcctcatt tctgtgatat gatttttttt gtagaagctc
   104581 atatatgagg aaagagcccg tgttgcagca cgggcttttt taatgttttg ctgaaatcgg
   104641 tttttttaat aattcttgat gtattcatac atattgcctt gcgtaagaat attttttctt
   104701 aaaatagcat tggcagacag cataacaagt gtatctgagc ttattctgaa tagaataata
   104761 ctccataaat ttttcgagat taaactgaga ttcatcagtc agttcgttct caatatagat
   104821 atttaataaa attagaatag ctattttatc tgcttctgtt tcaaattttg agtgaaaagt
   104881 tgtagaagta tcgtacaaaa ctgaaaattc aaaatgagag gcgctgaaat gtgcaagttc
   104941 atgagataaa tgaaaggctt ctgcagtttc accgtataga ttttcattca aaaaaatgat
   105001 tctgggtttt ggatagtaga aaccaggctc tttcatctcc atataaacta ctttcaaatt
   105061 gtattcgctc aacatttctt tcaatttcaa atacatacaa accatcactc caactattca
   105121 ttttcctcta aagctttagc aattgcaatc gctttacgca ttgtctcctt agatatttct
   105181 tttccatcaa aagaaaaaac agtatcgtct tctgataaat ccacatgttt aggggtttct
   105241 ctttcttctc tacctagaag gtagtctaca gagacatcga aatagtcagc aatccgactt
   105301 aattcatctg aattaggagt attatttttc cactttgcta gataaccgtt agaatatcca
   105361 aaattaattt ctaactgccg tatagatatc tttttcctct tcgccaagtc ttttattatt
   105421 tcataggtat tcatcgataa aacaaccttt ctaaatgttt acaaaaaaag tttagaaaaa
   105481 tacgcagaaa taatttgact aattctgagt aacgagctat actatatctt gtaaacagat
   105541 ttaacaacta aaaagacaac aaaaaacact attgatatgt aaatgcagac cgccaagaaa
   105601 gctttaaaat caatgttttt atgtcttatt taattatgct cttagtatag agtattactc
   105661 agatactgtc aattgaattt agaaaaaagt tgttaaattt gtttacgaat ataaaagaaa
   105721 ggaatgagaa atatgaacac accgcaaatt tttaatttcg aacaaaacga agttcggaca
   105781 attttagtaa atgatgaacc atattttgta ggcaaagacg ttgcgagtgt tttgggttat
   105841 tcaaacacta aagatgcttt gtcgcggcat gtagatttgg aagataagat ggggtcgcga
   105901 atcacgacct caggtcaatc aagagagatg acaatcatca acgaatctgg tttgtacagt
   105961 ttaatcttaa aatcaaaact tccctctgcc aaaaaattta aacgttgggt aacaagtgaa
   106021 gtgttgccag caattagaaa acatggaggt tatctaactc cagaaaaagt agaagaagct
   106081 ttgcttaatc cagatacaat cattcaatta gcaactcaac taaaagaaga aagaactgga
   106141 agattaatcg cagaacaaaa gattgcagag tacgaaccta aaatctccta tttagatagc
   106201 atattatctt ctacagattc agtaacaatt agtcagattg cagcagatta tgggatgtct
   106261 ccacaacaga tgaataaatt acttcataaa ctaggtattc agaaaaaagt cggtaaccaa
   106321 tggttattgt gcaaaaaaca catgaaccaa ggatacacaa aatctcatac aactgagatc
   106381 ccgaaagccg atggtggcac taaaattgta atgaatacca aatggacaca gaaagggcgt
   106441 ctatttatct acgaattact aaaaaaagaa ggatattacc ctcaaatgga tttagaggaa
   106501 attggttaga aaggagtttt agtatgactg acattgcaga aatcactcaa cgagatagag
   106561 aaaaaatcaa agaatatgtc gaaagttcaa agttcttaac ttacaccatg cttgctgaaa
   106621 gatttggaat tagcaaaagc tacttatctt taattttaaa cggtaaaaag acttctgcag
   106681 aagcaaacag aattatagat tcgattatca ctatgtacga attgtaaagg gaggaacagc
   106741 taatgcaata tctagaagca aaaatcccaa ttccagaagg ctatgtaatt atctcccaag
   106801 tggattatga ggagttaaaa aaagctgatg atactggtag atggatgacg ttgccagaag
   106861 tgctagaacg gattaacaga aaatatgatt ggtttacttc tagagtttta aagaacccaa
   106921 gatatagaaa tattatcgat atcgagaaaa acaaaaatgg atttgtctat tatccagttg
   106981 aaggaagaga cacatatcta tttttaagaa gtaaaacact tgaattttta gaaacaaatt
   107041 tttcggaaat cttaaggagg caagcggatg ggaaaattta atagagcgct agtgttcagc
   107101 gcaccgctaa tcatctacgc tttaggactt tggggaagca ggcaagcgtt gataggaacg
   107161 attgtttaca tggtttggat ttttatgggg cttgatgaag ctgaagctga gtacagagcg
   107221 aaaaagccaa ccgagggggc tgactaaaaa tgaatagaaa agagaaacta gaatgtatat
   107281 tactattact cagtttaatt ctttcactaa tttctctatt gggaagtttg tatttttgat
   107341 atcaacaatt ttgtggattt gggttctatt tagagtaaat atcatttttg tttggtgatt
   107401 aaggagttta ttaaaattaa ttttccctac ttcaaatgca aggtaacaag atatagcact
   107461 tttaggagga atatttagcg gtacagcttc agagtatatt ctattatcat cgactgatcc
   107521 tcctttagca attaatttct taaatggagt agctgaccat ctgcggttta agttagcgga
   107581 tgaaagttct aaattaacta acatagctgg ttctgttgaa tagttagaaa tgattacttt
   107641 tgtataaatc atatctgcag cgaagtaaga agcattaagt tcaacttcta gttgagggcg
   107701 cattcctttt atttttatcc ctgttaaaaa cgtactcaat ataaaactta ttattgacat
   107761 ccattgaaaa attgttaagt gaaaaaaatt caaaataaac accaccagtt tttaactaaa
   107821 ttataccaaa aaggagagaa gaaataatgc aagaattagt aattttgaaa aataaagaag
   107881 ctgtgactac gagcttacaa gtggcagaaa gcttcgagaa aaaacatcaa catgttttaa
   107941 gagatattga tgcactaaaa aaagatgtgt ccaattttgg acagatgttt gtagaaggta
   108001 atgaaccaga ttcatatggc agaaatcgac gagttttctt cattagtaga gatggatttt
   108061 tcttgctggc tatggggttt acaggaaaga aagctatcta cttcaaacaa aaatacattg
   108121 aagcattcaa cgaaatggaa gatgttattc gcaagaatac tgttcctcaa acaattgaag
   108181 atatgatgat ctatcaatta gaagaaatga aagatgttaa aaaagatgtt tccatgctta
   108241 aagatactat gcgaattagc ggacaacaag agtttgaaat taagcaaaaa ggaaatatga
   108301 aagttatggg agttctaggg ggaaaagaaa gccgagctta tgaagaaatc agcaaaaaag
   108361 tattctcaaa attttggtct gaatttaaac gtaccttttc aatcccaaga tatggcgagt
   108421 tacctcgtaa gagattcgat gatgctgttt catttattga aatgtggttg ccagaaactg
   108481 cgatccgtat ggaaattgat caactgaaca gacaacagag actttttggt gatgacaatg
   108541 aatagagctg aagcgctaag aatagggacg gcaattgcta attgctggtg gaaatactat
   108601 aaaccaatca tcctaagcca acaacatatt gacaagcaaa aagcatggca acaaataaaa
   108661 aagtgactcc gccggcaagc aaagagtcac aaagaaaaca catcataagg agattttagc
   108721 atatggaaaa agaactttcc actctagatc aatatttgat tgatcctgat tggggcaagc
   108781 cgaaaattga ggaaacaagt ggtcgaaaaa tcagacgaaa tcttttgacg aatgaagaac
   108841 tagcttggga tcaagatgat ttaggcaacc atgtaactat ttgggatcat gtttatctta
   108901 tccatctatc gaagcattcg aataaacctg aatatattta cgtcatcgaa gatggcttga
   108961 ttgatgcgct agaagagtac gacagagata acttgattga tatctcttat tacggaccag
   109021 gtaagaaata cattgctgaa atggaggcag aatttgatga gtgaaatcaa agggacaacg
   109081 aactttgaaa aactttttag tcgtaagtta aataaaattc tcaagaaaaa aggaaatttt
   109141 gattatttat cttgggctca cgcgtgggag attatgaaaa agaatgatcc acaggcaacg
   109201 gtaactatta atgagtacaa acactacagg gttgtttctg gaactcatca agactttctt
   109261 gttgaggaat ataaaccttt tcttatggat gaaactggga cttatgtatc tgtctcagta
   109321 acggttaaag gacacacgga aaccgaatta tttcctgttt tagattatcg aaaccaacca
   109381 gttgttaaac caaatgcaat gcaaatcaat aactcattga agcgatgctt tgtgaaagca
   109441 ttggctctac acggactggg attatatgta tttcaagggg aagatattcc aacaccacct
   109501 agaatcgata caaagaaatt aaacatgcta gagacgattc tagaagcttt caatgagcag
   109561 atgggtaaag atatgaccaa aaccttaatc gaatatgtta atgagcagac agataaatta
   109621 gggctcttag ctgataacgt tgaaactatt gaacagttaa gctatgagca atgtgccttg
   109681 atggagcgag caatagcagc taagagaaaa gaattagata agaagtgata tgagtgttta
   109741 aaccattaat cgattcatat tcagcggttc tgaaaaagtt caaaggaaaa gacataagcg
   109801 caaccatcaa tgaggaagtg aacattgatc gactaaagac gatgtatgac ggctacgatg
   109861 gtgatcgagt cattgaaatt cgttttattg atcctagacg tttcaccgta cagcaacgaa
   109921 acttcatcta tgcgctgata ggcgatattt ttatcgatac aggcatgcca acggacttct
   109981 ggaaggaatt cttctacttt cgttttgaag gtgtcacagg gcgcaaaata agcctgaaag
   110041 acgaatcgaa tacaactgtg agtgatgcca atgtcttagc aaatatcatc ttagatttca
   110101 tctttgaaca tcatattcct ttcaaagaag gctatgagat tttacctgcg aatcaagaat
   110161 attacttcta caaatgcatc acaaaaagag tctgctgcat ctgtggcaaa acaggagctg
   110221 acatcgatca ctttgacaaa gcgctaggaa gacgaaagcg caaagaagtt gatcatgcag
   110281 agtacacatt tgcagcactc tgcagaatcc atcacacaga gaagcacaaa ataggtgtga
   110341 ttaatttcaa aaataaatat caaatcaaag ggatcaaatt aaaccagaaa acaatcaaaa
   110401 agttaaatat tggagggtaa aaatgacaga acatcgaagt tattatgcga ttataccagc
   110461 caacgtaagg tacgacaaaa gacttaaacc aaatactaag ttgttatacg gagagataac
   110521 ggccttgtgt aatgaaagag gcttttgttg ggcaggcaat gagtactttg cagatttata
   110581 tggtgtgaat aaagagacca tatcgcgatg ggtaagtgat ttgattaagt ttggatactt
   110641 gaatcgggaa atcatttaca aagagggtac caatcaaata atcaataggt acctacgaat
   110701 taatcaatac cctattgacg aaaaacgcaa tacccctatt gacgaaaaag tcaaagataa
   110761 taatacatct attaataata catttaataa tacaaaagaa tatataagag agttaccgcc
   110821 ttcgaaaaaa tcgaaggcta agcccgtccg tcataaatac ggagagtata aaaatgttct
   110881 tttgtcagat gagcagatgg agaaactcaa aacagaattc cctaatgatt accaagagcg
   110941 aatcgaacga ctgtcagagt attgtgaatc atctggtaag acttataaaa actatttggc
   111001 aactattcga agttgggcaa ggaaagaaaa aagtgaacct aagaacgcaa gcagtggata
   111061 caagcgcaca ggaagacgag agaagcttcc tgaatgggca atcgaccaag aagcctatct
   111121 caagaaaaaa gcgctagaac gagctaatag acaatcaaaa gcaccattct aagaggtgga
   111181 aaaatgaaga tcgattatct agaactaatt aatgaaatag cgaattataa aaagggcgag
   111241 gaattagacg tcctgagaga cgtatatgat caactcgaag aagctggaat tgaaggaatt
   111301 aagaatgatc gttcgagttg gagtaagctc agatactatt tcgcacttta tatcgataca
   111361 acacaattaa gaaatttagc atataccaaa ttactatttg ttgattgtgt taaaggcttg
   111421 caaaaacatc ttaatgaact tgagcaggtg taatcagatg gacctaaaga catttacagc
   111481 acagattgaa ctaatgcatc aagaagcttt aagacaaagt gtatcgtacg aagacaagtg
   111541 gctcaacacg ttccatggcg gacgtgagag cgcacttgat caagtactca aattactgaa
   111601 aggagaatgt cgggatggat aagaaagcgg caatgcagcg aattatcgaa ttgacttatt
   111661 cagaagattg gcaaaatgac aaagaagctg cttcagaagt gatgaggctt ggaagagcga
   111721 tgtgggcaga caagagcaac aagccaagac cacgaaaaat cgcaatttgg cacggtgaca
   111781 aacttctagt gatagggaca gctgaacagt tagcaagtct cacaggcttg cacgagaaaa
   111841 tcgtgaggaa aagagcaagg tgtggctaca cagacgctaa gaagagaacg tttagatacg
   111901 tggaggaatc atcatgacaa cagaagaagt gattcaaatg cgtattcgaa gccttcagcg
   111961 tgagattgac gatctggaac gaacaaaggc agtgatggtc aatgaaacgg cgagaaaggc
   112021 aatcgatttg cacatagaga atttaagaag ggaaatccat cgattggagg aatgagcgtg
   112081 gataagaaag cagcaatgaa aagaattgct gaattaacca agtcagaatc ttggcaagaa
   112141 gacaaagaaa tagttgcaga agtccaaaag ctcggtaaat caatgtggac tgaaaagccc
   112201 aaacggagaa cgccgagaaa aattgcaatc tggcatgatg accgaatttt agtaacaggt
   112261 actgctgaac agttatctga aattactgga ttaagcaaaa acattatctg ggatagagct
   112321 aggagcttat ggattgattc aaaaggacga cagtttaggt atgtggagga gagataatgg
   112381 atctcattac acaatacagt gacatcatcc tcaagaaaat catgatgaag attcagaaag
   112441 ataaaaaatc aaaagaacga gctgaattag ttaagttaga aatggctgaa acaggagcag
   112501 gagtgcgaag tagcaggcat tggaaagcag cagcaaacat tgaattttat tacaacgaaa
   112561 ttcaaaaagg gttcgatcag atgcgtgagc tggatcggca aacaaattgg agcaagaaac
   112621 ttcatcaaga tcgtttcaaa tttgtagaga agtataaaga aatattagaa gagtatttga
   112681 ggaggacagc aaatgataaa aaaactcgtt caattcagca tggatttata tgatatcgaa
   112741 tcaggagcaa cactatctgt ggaatcggac catctaatca taaattttgg tggaaagcgc
   112801 cagattattt tgtgggtagt tgatgatgta ctgtttccag aaattgttca tgatttcgaa
   112861 gaatcaaaag cggttgagtt tgaaatagtg aaaaaagtaa tggaattgat tgaaaaatac
   112921 gaggaggaca gcgaatgata ccgaagttta gagcgtggga taaacgaaag aacgtaatga
   112981 gagatgtagc cgtcttgcat tttactaaaa acggcaaaac aaactttatt gaatattgga
   113041 taaatcctac cgaattgaaa tcatatcacg tgcgaaacat cgacctcatg caatccacag
   113101 gaatgaaaga taagaatggt gtggatatat ttgaagggga tatagtatta gtcagcgtgc
   113161 gaaatggctt cgattactta gataataaag tctgtattgt caaaaattca atagattatt
   113221 ccggattagt ttgtgccact gttgatgaag acttagagta tcaaattttt aacacagagc
   113281 tgtttgaaga atacacgtac gaagtcaccg gaaatatata cgagaatagc gagttattgg
   113341 aggaacagcg atgaataaac aggaagcaat caaaaagtta gaaagtatta aagcgatagg
   113401 aaatgatgca atagctgctt gctataacga gagtataaat tcaggtatta cgttaatgaa
   113461 aaaaatagac gaaccgcaga aaccagttat tccacaactc gtggccggtt ggcttgagaa
   113521 atctacggac ccttttacaa aagctgaaaa aatagcgtat ttaatcaaat ctaaagatgg
   113581 tgattcatat tatttctgtg attggtttgt acgagatggc atagtgacgc aagagcaagg
   113641 agaagaatta ctcgcttggg caacaagaca atcatatgaa acactattga gcctatacaa
   113701 cggctacgag gttgagaaag agccgttatg ggcaataaag aatgccgatg gaaactatct
   113761 tactaaatgt gctttatggg gaaaagatgg agtaaattat agttttgaat gcaatccatc
   113821 tcatcgattg cttttcactg ataaagcaac agcggatgct gcagcattgt tggtgaatgg
   113881 aacagtggaa gaggtggtag aaagatgaaa ctaaaagacg gattttacgc tagcagtcac
   113941 ggtatcggcg gtttaatgct agatatgccg acaaagaacc ctaaaacacg caagaaatca
   114001 aaattcaaag tcggtgacat ggtccgctgt gaagcagaag agttcgttta tccgttcaga
   114061 ggatacgtta aaaagatact gtcaaactca gcaatcattc gtattgaaaa tacaatgaag
   114121 tgtgatcgtt cgactgcaaa acacaagcat tatttagctg tagcgagatt agttgacatg
   114181 gaagtaatca agagcaaata aaaaaagccg gatcgctccg actgattcaa taaatccaac
   114241 acatttatta tatcacataa aggagcggtt tgacttgatg caattgttac gagaggtaga
   114301 tttcaaacag acaagatgta atgcgagaga tgtgctgaag aactttcggc gtttggagcg
   114361 gatggcaggt cgctctttga tagatattaa gtcgccgatt ataacggata tgccgaaggc
   114421 accgaagcat ggcaataagg cagaagacgc gattattcag atgatggata tagaaacgga
   114481 gagagatgcg attctagcgg ctttgatggc tcttagtctg attagtcgtc agatactcta
   114541 ctacagcttc tgtgtgccag atagcttctc aaactacaga attagccgtg aagtgggtta
   114601 ttcagaaaga agtatacaac ggatgaagtc ggaagctcta atagagtttg cagaagcata
   114661 taaacacgga aaaataattg cttataaata atttggcggt tttttggcgg aatgatggcg
   114721 gtttttagac atttaccagt gttattatgg tagtgtcgaa agattaggaa acaggatcga
   114781 caaaataaac gaagggaggc aatctccctc atcgttttaa acttcttctt agatagacag
   114841 caactaatta tgaagaaaag gatgtgaatt caactcctcc taaattcttc atcggttgct
   114901 gtttattttg attagacagc agcactcaca aaactaaaca tgttcttgtc gtctttcaac
   114961 tgctgctgtc tattaattta tgtattggag ggaagaaaaa tgaaattatc agtagaaggc
   115021 actccagaag aaatacaaga attgctccaa gctattggta gtagcaagga gcaaaaggta
   115081 agtgtttcta attcagatat tgacggtatt tgcaattgtt taaacagaga aaaaatatct
   115141 aatccttact aagagaaaat atgttcgtta atgaatttcc aattttcctc tgtagctcta
   115201 ccttgataat ttttttgcag ttcacagatg aataaggaat cgttattatc aagtactgta
   115261 tttaattttt cacacatttg atttggattc aaattagttt taactaacca aaaagatttt
   115321 tgtagcttta tatatgcccc aaattctttt attatttcaa atactttatc atacttttgc
   115381 cctgggttat taagatcata actaatcatg tagggtttat acatgttgtc ttgcacatcc
   115441 ttgttttata tttcagcgga ccactcgctg ataaataaaa ttatacgctt agtatttatt
   115501 ttcacaatat taatttatcg taataacttt tgagtaaata gaacaaaaaa cctgcactag
   115561 tttccgctag tacaggcagt gactatatcg gttgataatc tagcatatat taaaaataat
   115621 tgcaagaaaa gaaatttata gtggtttata ccaaattatc aaagcaatgt tattttgttg
   115681 ctgtctattg ttttttaatt attcacacga taactaaagg tgggtgaaga gaaatgattc
   115741 cattaataat ttcaattttt gcgctctgtc ttaatgtcta tatgattgga tttaaaaatg
   115801 ggcaaaataa aaaatagtag cagccaagaa taattttata gtgtcactgt ggcggaaagg
   115861 gtagacgcta agcatgtgtg ctaggtcaat gcttcggcaa ccatgcaagg ttcgattcct
   115921 tgccagcgac attaaatgcc tatgacggtt acgactaccg aaaaaagatc gttaagaagc
   115981 tatacggtgc tacgtacggc aatgtagtaa gtgtgctatc tgtacaccac caagcttcgg
   116041 tcactgtggc ggaagtagaa gacgcagcgg taaatggcga gtagcctcgt gagagcctgg
   116101 taagttctcg tgagtggtgc aatcccactc cagcgacttt aagcaaccga ggcatcggcg
   116161 gtttaaaaat ataggggtgc gcaatttcgt acgcgttttg tgcatcgtgc aagttactat
   116221 tacatattag atcactcttt gagtggtctt tttatttttg cacaaaggag gaaacaacaa
   116281 tgtatagacc acaatactta gaacagaagt atgaagtaat cactgttcat aaaggtaatg
   116341 gcgaaaaagt atatgagtat agaagaccaa taaagagcga tacatataaa cgaaaggaaa
   116401 acaatgaagt tattccattg tatggcaaaa gaatagctaa gcattaaata agattgcgaa
   116461 aggagacgga acatgaccga ggaattctat agatggctat tacagttgac aagagaagat
   116521 cgtttggtta agttctatca gtctcctaaa tggcgcaggc ttagagagaa agcgatgaaa
   116581 cgagatcact atgaatgcca agagtgtaga agactaggta agtatcatag agtagagaac
   116641 gttcatcata taaaggaagt caaggataga cctgacttag ctttagattt agataatctt
   116701 atttgtttat gtgttgaaca tcataatgaa gttcatggca gatatcttac agcattagat
   116761 aaacaagaga agaagataga aagctttgct aacttcgatg caagtgaaag gtggtaagtg
   116821 catgatcatc aatgataatg gcagagagta tgatacagaa aagattgaag agtattcatc
   116881 ttatactcag ggattaatta aacgtttgat atacgttcgc tatgtaggta ttagggatct
   116941 gttatcagat aactgttgta gtaaatacaa agtgaatcaa gtaagagaag cgttgaataa
   117001 agataataac gtcgaaagaa taaaaaatgt ttttggatat agtattgaag agattaatta
   117061 ttacattgac ttcgctgaag ctttcattcc gatggtgaga taaccccccc ttaaaataaa
   117121 tcgcaaattt tttgggggtg atgaaacgga gggggctgtc aggaaaagag attttttcga
   117181 actttatcat gaaaggaggg ctaaaatgtt taaaaacgaa ttgtctcaaa atcgctacag
   117241 agaaaaatta cgccgctctt taataagcca attggaaagt cagaaaacaa atattgagcc
   117301 attcttagat aatgttgatc gttatatcag tttatgggaa acggcgatat cactggaaga
   117361 agatatatcc gagaacggca ttagactgga gaatggtaaa aagaatgaat cagtagcgtt
   117421 gcttgtttct gtcaacaaac aaatgggatt gatgttggat aaacttgcca ttactcctga
   117481 attggtaggt gaagcaaatg aatcaattcc tgagttataa gcatattgaa aattggttca
   117541 aagctataga agaaggcact atcaaggtat gcaaagagca attattgcta aaaaattatc
   117601 tagaagaaag agtctttact agagaagata tttacttcga taagcagatg gtagaggatt
   117661 caatcaatat accagcacaa tactttccat tcgaattaat tccgtgggaa aaatttctac
   117721 aatgttttat ttatggtgtt cgatggaaaa aagataaaac actagtgttc aatagatatc
   117781 tttcattaat gggacgtggt aatggtaaaa ctggttttgc ttcttggaac aacttctttc
   117841 tactaaccgc taaacacggt attaaaaatt atgatattga tatctatgcc aataatgaaa
   117901 gccaagcaaa gactagtttt gatgatgtat ttaaagtaat taaagatcat cctgatttag
   117961 ataaaaaagt atttaaagct acgaaggaag ttattcaaaa tatcgctaca aacagcaaac
   118021 ttcgttataa cacggcaaat gctagaacaa aagatgggaa gcgaccaggt gcaaaccgct
   118081 ttgatgaaat tcacgaaaat gaagattatt caatgataaa tgtggctact tctggtggtg
   118141 gtaaaattcg agattataga gaattttatg atacaactaa tggtcatgtt cgtggtggtc
   118201 cgcttgatga cattatagaa gaatcaaaaa tgattctttc tggagaactt ggaattgaca
   118261 aggatggagc agaattttct agtttgtttc catttatttg tcgcttggat aacgataatg
   118321 aagttgatga tcccgacatg tgggaaaaag cttgtccaac tattaattac aatgcagatt
   118381 taaaacggaa aatgtttcaa gaatactctc aaatgcaacg taatgctggt ttaagactta
   118441 cgttcatgac caaacgaatg aacagaccta tggaagatac acgatttgct gttgcttcat
   118501 atgatgatgt tctgcatacg aaagaaaaag aatttcctga aaaaatggat gaagtgatag
   118561 gaacagtcga ttttgctgat agacgagatt ttgccagcgt tgggttgcta ggaaaatacg
   118621 ataaagatgt ttattttaca caacatactt ttatccacga atcagccctt cgattacaaa
   118681 acatcaaacg agaggttata gatatttcta tagatcaagg aaaatcacag atcgttcatg
   118741 gaaaaaatat agaagctgat tatattgtag gttggtttct tgaaatgagt aataaatatt
   118801 atattaaaaa aatcgctatg gatatgtacc gtgcaaaaat attgaagccc gctttagaag
   118861 aagcaggttt tactgtggaa attgttcgaa gcggatctgt tacacatggt atgttaaaag
   118921 atctggttga tgaccttttt attaatcaac gtttattttt tggtgacgat gcgattatgc
   118981 gttggtattg catgaatgta tatgaagagc atatttctaa tggaaatata cgctatgaaa
   119041 aaatagaacc tgaaactaga aaaacggatg gctttttttc attccttcat ggtttgaatt
   119101 ttttagatga tatttatgat tctgctcctg taacagtcac aaatagctca gtagaaaata
   119161 caggaactgg atttactcct ctagtattct aacttgaaag gaggtgagaa agtggggatt
   119221 tttcaaaagg cggtaggata cttcacaaaa aaagcaacgg ttcctttaga agaatacttt
   119281 tgtaaattgc aagttgattt tgtgtatcga aaatttgcga ttgaaacttg tattgatttg
   119341 attgcaaatg cgatgagtaa agcggaattc aagtcatatg aagatggaaa aaataaaaag
   119401 aatgatcttt actataggct gaatgtagct cctaataaga aaaataatgc aacagaattt
   119461 agaaaaaaac tgatcaggag attaatattc tacaatgaag tattgatcgt ttctccgtct
   119521 aataattcta gcgaaatatt tattgcggat agttgggatg tcacagaata tgcattgaaa
   119581 gatgatgtgt tttctcaagt gcaaattaac aacatagtcc ttgatagaga atttctagaa
   119641 agtgatgtta tctatataaa atacgcagat caacaaatta ggcaactagt cgatgcgtat
   119701 tatcaagcgt atgggaaact catttctagt gccatgaatg tttacaagcg ctctaacgct
   119761 cgtagatacg tactgaaagg gaatttattc cgaccgcaag acaatacaac acaagatcaa
   119821 atcaataaaa tgatgacatc acaatttaag gcttttatgg aagctgataa tgcaggtgcg
   119881 gtatttcaat tacaaaatga gtacacatta gaagatttca gcggaaactt ccaaagcaat
   119941 tcaagagata taaaaaactt aatagacgac atctttgaga tgacagcagc agcgtttcac
   120001 gttccgaaaa acctactaaa gggagacatg agtgggttat cggatcaagt ggacgctttt
   120061 ttaatgttcg aaatcatacc gattgctgaa cttattcagg atgcgtttaa cgctagtctc
   120121 tatgaagtag aagaatactt gtcagggaat tttgtacgtg tggatacaac tatgatcaag
   120181 attactagct tcaaagattt ggttgacgct attgatgtag gcattagaaa tggagtattt
   120241 acaatcaacg aaggaagaga acgcgttgga aatgatcgct ctgataaggc gatggcagat
   120301 gaaatattta taactaaaaa caatcaacaa gtatcgaaag gaggtgaggc gaatgacgac
   120361 aatgaaaaca tttctagcag taaagaatga aggcgcagta ccgcaaattt ttattcaggg
   120421 atttattggt tctagttggt tctttgaagg gaatactgac aagggaatca aaaatatttt
   120481 ggatagtcta ggtgatcaag aagaaattga agtagtaatt aattcaaacg gtggagacgt
   120541 atttcaaggg attgctattg ggaacttact taagtcaaat aaagcaaaag ttaacgttgt
   120601 gattaacggc ttagccgcta gtgctgcttc aattatcgca atggctggcg atactataaa
   120661 aatctacaac aatgcacaat tgatgattca ccgcgcttcc acatacggag aaggaaatgt
   120721 cgatgacttc cgtacgattg ctgaccaact ggaatcaatt gataaatcgg taaaggcttc
   120781 atataaaaca cgattcaatg gcacagatga agcattgcaa gaacttcttg aaaaagaatc
   120841 gtttatggat gcagaaacag ctttgagtta tggattggtc gatgaaatta tcgatgcaga
   120901 aaatagctca ggtactgaag ctaaaaaaga acaaagcgtt gaagaaattt tgaatgacgt
   120961 taaagaaaaa agagcagaaa aaattgctgc atttacagca gcattaaata aaacatttgg
   121021 acaaggagat gtaaaataat gacagttaaa aatttaaaag gtgtaacagc tgcaagcgac
   121081 caattgatga aagcttttaa agatggtaac gaagaatctt ttagcgcagc tatggtaagc
   121141 ttatctaagg aaattcagga taaaatttta gaagaagcaa cagcaaaaaa tcaagatcaa
   121201 ttagtattaa tgaaccgtgg tcagcgtgta ttaactacac aagaaacaaa attctataac
   121261 gaagtagtga aaaacgaagg ttttgcaggg gtcgaagaat tagtgccagc tactgtattt
   121321 gaacgtgtat ttgaagattt agaacaatct catccactat tgcaaaaaat tacttttgtt
   121381 aacacaactg gtgtaacaga atggattgtg tcacgtggag tcaatccagc atggtggggt
   121441 aaactttgcg aagctgttaa aaaagtttta gataatggct ttgatgtaat taacatgaag
   121501 cagttcaagc tatcaggtta tattcctgta tgtaaggcaa tgcttgattt aggtccagta
   121561 tggttagatc gttatgtccg tactgtttta gtagaatcat tgagaattgc attagaacaa
   121621 gcaattgttg atggtactgg taaagatatg ccagtcggaa tgatgcgtga catgagcaaa
   121681 caaactagcg gagaatatgc tgaaaaaaaa gcagaaccta ttacagcttt agatgctgta
   121741 actatgggcg gtttgatggc gcgactatca aaattcaata tcgaaggtgt gaatgatccg
   121801 atttatcgta atgtgaatcc ttctgatgtg gtcctaattg tgaatccaac tgattactgg
   121861 tctaaagtat tcccagctaa gactgtacta actgctaatg gagaatacgt acaagtattg
   121921 ccagtaccag tttcagattt gcagtcaacg gctgtgccag aaggaaaagc agttattggg
   121981 gtagcctcag attacttcat gggtgtagga tctacactaa aaattgaagc ttcagatgaa
   122041 taccattttg ttgaagacga acgcatttat ctagctaaac aatatgcaaa cggtcaacct
   122101 aaacgtaacg atagtttcat tgtattagat attagcgctt tgggaactac tactacaact
   122161 acaaaaccaa caaccacaac aactacaaca caagcgtagg tgatcagaat gaagtatatt
   122221 ctttgtcagc cggcaatcaa tcggtttaaa tgggagcttg aagtttgttt aactaatctg
   122281 aagaaactag gaatcaaaga tatcgtattg cttttcagca gacacgatga tcagattcct
   122341 attttttttg agaaggaata tggtgttgaa gttcatgtgt acgatgatct gcgggacgac
   122401 aaagagtata ttccttcgat taaaccatat ttatggtgga aatatttaga agaagatcat
   122461 tcgcgtgagg acgaccgata tttctatatc gattcggatg tcattttcaa taaaagaatt
   122521 aatttgcgca aattgccttc taaagatgat gtttggtatt gtagcgactg ctgtagttat
   122581 ctaagtcttg attatattag aagctgtgaa aacggagaaa atattctaaa agatatggca
   122641 aacattgtaa atgttacagt agaatctttg gaaactataa acactaattc aggaggcgca
   122701 cagtgggtta ttaaccgtcc taaagcgaat tattggaaaa aggtttatct ggattctaat
   122761 cggctatatc gctaccttag agggcaaaaa acaaatatac aaatctggac agccgagatg
   122821 tgggcacagc tttggaacat gatgtatttc aatattggtc ctaaagttca cgaggaatta
   122881 gacttttgtt ttgctactga tccaatagaa aaagttaaag aagtaaaaat cttacacaat
   122941 gctggagtaa caacaaacga tgaagattta tttttcaaag ggagatacgt gacttctacg
   123001 ccttttgatg aagatttatc atttgtaaac aagaaaaaat gctcttacgc atatgttaaa
   123061 gcaattaagg cggtggttag atgacgcctg aacaagtgac tgaagaattg ctaatagctg
   123121 tgaaggataa tatttacgtt acctggaacg aagaagatga gtcaattaaa aagatgatag
   123181 ctaaaaatgc tgtttatctt caaagtaaag tgagtacaac actttctttt tctcctgaaa
   123241 gcttagaata cggattgcta atcgaaagat gtagatacga ctggaatcgt gctttagatg
   123301 agtttgaaca aaatttcgct agtgagttat taggtttcat tcaacattat gcgctacaag
   123361 aatatattgc aggtgatgtg aatggcgaat aatcgtagac tcgaagaaac attcaacgat
   123421 ggttggttaa agattttgac gcaaactacc aaaagaaatg aactaggaaa aaagattggt
   123481 gtagaagata cagaaatcac ttctttaaaa tttagaaatc tttccatgag agatagtgat
   123541 ataacagcta tggatgcgat gggatcgaaa ttaactaaga aagtaaagac tccatttcat
   123601 ccaatcgcca agaaatttaa taaagatcaa tattttatcg taatcgatag tatgcgttac
   123661 aacgttatct atgccgatta cgataatttt tatatctatt tttatcttga aagtgtgggt
   123721 gaatatggtg attgataatt ctaaagaaaa agaacgttta aataagcaaa tttctgctat
   123781 caaaacttcc ttagaagagc attttggcct caaactcttt caagactccg taggcgagga
   123841 tgagctacct gatgatttta attacttcat tctcgaaaca ggagaaatag aaatgatcac
   123901 tgagccaaaa tatagcgtgg gtcaaaatct atatctaact ttctattcag aaaatagaga
   123961 agatttaaca ggagactcac tagatattat ttcattgatt caaaatcgtt cgattcgttt
   124021 tcagagaatg gatcccaatc atttaaaact agagaaccaa gatcgctata tcgatcaatt
   124081 ggtatttacg tttagacgat tattgaagag tgattgtcat ggctaaaaat agttgggagc
   124141 taaaaataaa tggacatgat gaacttcttg tgcggatgga acgctattca agcgagagcg
   124201 aacgactgat taacgaagca ttgaaatcaa aaggttcggc tattgcagtg gataggatta
   124261 cagaaaaaat tcctgtttct gaagcagatt taagaagagg gcaccaacac gcaaaaaata
   124321 gtcgtccact taagactcaa tacattaatt tgggtttcat cattagacct acaagaaaat
   124381 ttgagtattt aaaatatcct gatttgggga taggtacttc taaaagaaat cagccggacg
   124441 aatttatgag aagaggatta ggtcttgcac ttgatccaat tacagaactt ctgattcgtc
   124501 aattcgataa attaaataaa tagggggaac aacaatggct aaaacaaaaa ctgtagtaac
   124561 aacgttcgat aacgtaagta tcaaacgaat tgcttttaat tttaagaacg caggaaatgc
   124621 aatcgcaacg aattgtaatg gacaattaga tggcgaaaca gaaatgcaaa cggtggttaa
   124681 aaaatgtgga gcgacagaag taaaatcaaa atctaaacca atcaatatga cggtaacaat
   124741 tactgcacat gtaccgatgg aagtttatcg acgtttcaat gggttgaaac aagatggacg
   124801 tattaaacca ggcatttact cttacggtcc tgattccgta ggcgaagatt tctcacttgc
   124861 tgcagagatc gtggatgact tcgaagaaaa tagaaagtta gttggtatgt tagcatgcac
   124921 ttcgaataca ggattaacat tctctattga aaatggtgcg gatgaagtag ctgcgttaga
   124981 actagaaaca aaagttatgc aagatgaatt tggtaaattt tatcatgaag caattgttgc
   125041 agaacttgaa gaagacttaa cagatcaatg gatgacgaat ctatctgctg atgtgattaa
   125101 aaaaacttca gttgtgacaa ctacggccac tcaatcacag taaaaaaaac ggaggtagcg
   125161 aaatgaacga agattactca aaaattgaac taaacgatgg aacaattttg aatttagaac
   125221 ctaaactgaa tatcaagaaa ttattgatga tcaatagaga ttttaacaca gacgagtttg
   125281 caaaaatgac tgtgggaaaa ggatccatgg atatttctgt tattcaaggt gcaaaggctg
   125341 tgtatattgc ttaccgccaa gcgaacatga ctgattatat ttcattcgat gaatttatcg
   125401 ataaatggga ttttgatatg gctactgcca gctatattta tcaattgatg atgttcaaac
   125461 aagcacgcga tgcttatcaa aaagaatttg aaaaagcaaa taaggaaaaa aagcttcaaa
   125521 agtaaaaatt ccaaagctct tagttgaaac gtgggtcgat gtctattcga tgttgaccga
   125581 cgttttttct atgccttcag atttggtttt aagcgatatc tgtttagatg acattttgca
   125641 aatggcttac aacaagagtg cttatgaagg atggaaaaac tatgcaataa accaatccca
   125701 gaaaaactaa agaaaggagg taaaaaatgg ctaaaaagag aacagaagca gaagtaactt
   125761 tcatagctaa cgatgacgga ttgaaatcta cgttaaaaga aatcagtgct gaattaacta
   125821 aaaatagagc agaattaaaa ctagaacaag ctcaattaca acagactggt tctgaatcag
   125881 acaagttagg aagtaaatta tcttctttag aaaagcagta tgaattacaa agtcaaaaag
   125941 ttgaagtaac tagccaacgt ttagccaatg cgaaaaaata ttatggagaa aattccaccg
   126001 aagttcagaa acttgaaaga gaactgatta atcaacaaac agcgcaacaa cgtttgtcaa
   126061 acgaaattga taaaacgagt aatgcactag ctcaagcaaa aggcgaaata cagacgtacg
   126121 agtctacaat gcaacagttg gatagcgaac aaaaaaatgt tcaagctagt gcttctctga
   126181 ttgaatccga atacaaaaaa tggcaagcaa ctgctggtca atcagcttct gaagccgaga
   126241 aattagcgaa agcccaagaa tatgtttctc aacaatctga aaatgcggag aaaacgatag
   126301 atatcctaag acgacagtta gaagctacac agtctgaatt tggcgctaca tccacagaag
   126361 caatgcagat ggaagcgaag cttaatgatg ctgaacgtga atttgaagag ttaggacaag
   126421 ctgctaaaaa tgtagataca actaacttgg acgatatcgg aagcaaaata gatatgaata
   126481 atttaatgga agcttctgac gttttaagcg acattggcga taagcttaca gaattaggga
   126541 aacaagcagt ggactctgct aacagtgtag gtagttccca gagtaagata caagctaatt
   126601 ttggtttgtc taaacaagag gctgaagaat taacgaatgt agccagagac atttattata
   126661 aaggttttgg agaatcgtta gatcagtcca cagatgcatt gattttggta aagcgtaatt
   126721 taggagattt aaataatcaa gatttacaaa atatcacgga acaagctatg gtcctagaaa
   126781 acaccatggg cgctgatatg gatgaaacgt tacgtggtgt aaatggctta atggtcaatt
   126841 tcggcttgag tgctcaagat gcaatggatt taatggtttc gggtactcaa aacggtttag
   126901 ataaaacgca cgaattaggc gacaatatgg cagaatatag ccaattatgg agtcaaatgg
   126961 gatattcagc tgatgaaacg ttcggaatgc ttcaaaatgg tttagatgcg ggtgcttata
   127021 accttgataa agtcaatgac ttagttaagg aaatgggaat atcgttaaca gatggtcgat
   127081 ttgagcaaaa catggatatg tttagtgaaa gtactagaaa agcttttgaa gagtggaaaa
   127141 atggcggagg aacacaaaaa gacgttatta attccatgat tcaagatttt agcaatatgg
   127201 atggtcaata cgaccaatta aataaagctt cgacaatttg gtctgcgctt ggcgaagata
   127261 atgcgatgaa agttgtccaa tctttaactg atgttaacca tacatttgat gatgttagtg
   127321 gatctgcaca aaaaatgaat gaagattcta ctactccgtt gcaagagttg aacgggaaaa
   127381 tagctgaatt aaaggattca ttagctccta taggcaacac aatcatagat gcactcgaac
   127441 cagtaattga ttttctagga aagatggctg atgcgtttaa taatcttcca caaccagtac
   127501 aggatttcat tgttgctata ggtggtctta cagcagcatt tggcatactg ttaccggcaa
   127561 tactagccgt gtcatattta tttggtccga tgatgcttat aattggagga attatagctg
   127621 ttatagcagg cgttattgtg gcaattaaga actggggtgc aattactgac tggtttagtg
   127681 gtttatggaa aaaatttact gattggttgg gtgatacttg ggaaagtata aaagacggag
   127741 cctcatcagt ttgggatggg gttaaagaaa cctggtctgg atttgtagat tgggttcaag
   127801 atatttggca aggagtttct gattggtttg gagagctatg gagcggatta gttgaaggag
   127861 cttccaacat ctggcaagga gtccaagaaa cttggcaaac attcgttgat tgggtttcaa
   127921 atatttggaa cggagtcaaa gaagtatggt cgattatttg ggcagacatt gtaggaattg
   127981 ttcaaatacc atggacatta ataacgtcat tgattcaagc tggtattaat attatcgtgg
   128041 gtatttttga tgtagctgga cagttattgg gcgcagcttg gcaagctgtt tggacaccta
   128101 tttctgattt ccttaaaaat acttgggata ctatgacaca atggataagt atcgcttgga
   128161 atgggattgt aactacattc catactatat ttgatccagt agtggcatgg tggaatggta
   128221 tatggacagc tattagtact acggcttcaa atatttggaa ttcaattagt gcaacagctt
   128281 ctagtatttg gaacagtatc aagaatacaa tcactagctt ggtacaagca gctgctacag
   128341 taattcaaaa tatttggtca actgtatcta gttggttagg tggaatttgg aattcaatca
   128401 gctctacagc atcaaatatc tggaatagtg tgactagtag tataagcaat gctataaacg
   128461 cagctaaaag tgccattcaa agtgtttgga atagtatatc ttcgtggatt agcggaattt
   128521 ggaacggtat caaaaatact gctttgaatc tttggaatgg aattacaagc actattagct
   128581 ctaaagtaaa cgatggaaaa aatgcaattt caagcggttg gtccaatcta acaggtattg
   128641 tttccgacat attcaataat gttaaaagta caattgctaa catatgggaa ggcatcaaaa
   128701 agactgttag cgctccaatt gattggatta gagacaaaat cagtggcatt tttgataatt
   128761 tgaatatttc tataccacat attccgttac cggaatttat catggaaggc agctttaacc
   128821 cgctaaaagg tcaaatcccc catttgcgtg taaaatggca tgctaaagga ggtatcttta
   128881 ctaaaccaac tttactaggt ggaatgaacg gtgtcggtga agcaggacct gaagcagttt
   128941 tacctttgaa aagatctgtt ttgcaagaaa ttggtgatcg tatcttgagt agcacatcag
   129001 tttcatctag ggcacaaacg attcaacctg tgaataacta cgaattcaat ttcacaattg
   129061 atggtaacgc agatgaggtt actatgaagc aaacaactca acaaatcatt gatagcatta
   129121 caaaaattca aaatgataat gcttcggcat ggcgttaaac aggagagtat ttctcctgtt
   129181 tttttagtat taaaaaggat gtgaaaaaat gactgattgt atacattcta taatcgatgg
   129241 atttcctgat tatttgcata aattggcttt agctgaaaga ccaaccatac cttctccaaa
   129301 aagacagaga gttgaaactt ctgttttagg taggttaggt ggcttagtac aagattactc
   129361 gtttgaagat atgtcgttta cattgcacta taactattta gaggatgtgg aagaccatca
   129421 agcgttcaag caatcgtttt atatcatgcg tcattggtta aactatgcaa agaaattaga
   129481 attctctgac gatcccaacg tctattacgt tatccagact atcgatattg gggatgcaga
   129541 aaacgatatt gttgaatggg gagagttcga tgtaaatatt actgcgaaac cattcgcaag
   129601 agttcaagaa gatgtaccta taaccgtaga taaaccacag tcatttaact tgctgaataa
   129661 tagtttagaa gaaagttttc caaagattat catcactcct tcagctactt catgccagtt
   129721 catcttaaat gattatgtgt ttagtttcga aggcttagta gcaggaactg atgtagtcat
   129781 tgatagtgat ttgatgcttt gctacgaaga gcaatcggac ggagatattt tagatcggtc
   129841 caacaaaatg aagaccatgc aatatccgac attgcaagtg gatatcaatc attttaattg
   129901 cactggtttg agcaaaatac aaatttatcg taacgggtta aggtaggtga aatagatgat
   129961 cgataattta ataactattt acgataaaaa tgacgcgaat aatttagctg aacatttata
   130021 tgatacgcaa ggtttaggcg ctttgtcaga ctggttaaca gctactgtta gcaataaact
   130081 aaacggagcc gagatatttc agggtactta ttcaataaac ggaactaatg cagatttgat
   130141 tgtagacgga cgtattattc agtgttatgt agatgaaaat cgagcaaaac agcgtctacg
   130201 gatttattat gcaaaaactt ctgtaatagg caatacgata gaagtaaaag ctgaacctat
   130261 tttcaatgat ataagaaaat cggtgttgaa taaatatgac agcggaacag aaaagatcac
   130321 tgctactcag gcatggcaaa acgcaaaagt tttagcgaaa ccagctatcc cttcgcagtt
   130381 ttctttctcg tcattagtag atacgcttgc taatgtgaag atagaaaagg cgaatttttt
   130441 agaattcttt ggtggaaaag agggatctat tctagatcga tttcatggtg agtttctaaa
   130501 agataataac acattacgtc atgaaaaaag tctaggtacg gatcataaaa tcaaagcgat
   130561 ttatactaaa aacttaactg gtcttgactt agagattgat gctcaaagtg ttttagttgg
   130621 agtttatcca ttcattagca gctcttcaga aggagaagac gagatcactc taccagaaga
   130681 agttattttc acggattacg tggatgatta tcctgctgga tatgtttctt ttgttgattt
   130741 taaagacaaa gcgactgatg tagccacatt aagggaagct gctaaagact ggttgaaaac
   130801 aaacatagat aaacaaaaac cacaagtgag tggttcgatt gaattagtac cattgaggca
   130861 tcaaagaggc tatgaaaaat ttgttgatct agaaaaagtt tcgatgggtg acggagtaga
   130921 tgtgtatcat ccacagttaa aagtgaatat gtcagcgaga attgtggaat atacgtttaa
   130981 tgttctaacc aattcatacg ataaattagt tgtaggaaac gtcaaaacaa acttcttaga
   131041 aaacacagag aataatgtca gcaatttgat taatgatgcc attgatcaat tgaaaaacgg
   131101 tggcgaaatc agtgatttac tcaatgatat tgtagatcat caaactgata tgattactgg
   131161 tcaaaatggt ggttatgttt tattagatcc taaagaagcg cctagtcgta ttttgattat
   131221 ggacacacca gataagaata ccgcaaggaa tgttttacaa atcaacaatg ctggtattgg
   131281 tttttctaaa actggcatta atggaacata tgaaacggca tggacgttag atggcggatt
   131341 caatgcctcg tttattacgg ctggtgaaat agtaggaatt actattagag gtactacatt
   131401 aattagtgat ggtgctgatt atagaacaag tattgctaat ggcaaaatga cttggtactc
   131461 aaaaaaagtt aacaaagata ttatggagct agaagcacgt gattatgtaa gtgctgatgc
   131521 cggtattgta tcatacacca tgaaaactgg tggtggtttc atgattagaa atccacaggg
   131581 taacttggtt tttagtacgt gggataatgg taataacaga ccgtttctat cttttggtgc
   131641 gcccaatttc aggtatagca atgctagtta tgtaacttct ggcgacggta gttctttaag
   131701 cattaatggt agtgcgggta actcatggga atttaaggta gctggtagga ctatgaaatt
   131761 tactagtgat ggtatgctaa cgttaccagg ttgttttttt ggttcatggg aagatgggaa
   131821 acttgctagg tttgaacaat caacggtaca agtatataaa gattttactg ttagaggtac
   131881 taaaaactca actgtaccaa cagaacatta tggacaacga ctattgaacg cttatgaaac
   131941 tccagaatat tatttcgctg attatgggga agccgttaca ggtgacaatg gtaaagttcg
   132001 tgttgatatt gaccccatgt ttgctgaaac agtaaatcta agtcggtata tgacacatgt
   132061 gacacctaca gaactagttt tgtgtgctgt tactcatgaa gatattgacc atttcatcat
   132121 tgaaactagt aagccaaacg tattagttag atggaattta gtggcacacc gtctagggta
   132181 tgaagatatt agattaaaag aggatacagc atatgatagc acagtgcttg accaaaaacg
   132241 tttttaaaac gaagacaagg aggtatataa atggctagca gtttatataa tttggcttta
   132301 gatttcagca aagaattaaa ctacaccaaa gctattatgg ctcgtcaagg tgataaaggg
   132361 attacggtga cggttaaacc gtttctaaat ggcttgcaga tggatacgag tggcggaaca
   132421 tttactttaa aaggaacaac accatctaac cgttacgtag ataatgttgc aactagtgta
   132481 actagtgaag aagtcacgtt ttctcttgat ggcacattta tgagtgaagc aggatattat
   132541 aaacactgct acgtagaata tagaaaagac aatcaaattt taacaacgca agatatcatt
   132601 tttttctcac taggagtgtc tgacatttcg caaggccaag ccgatgaata tgtttcgcaa
   132661 ttagaagagt tgattcgaaa gtacaacgaa acttttgatg cttttatggc tgaaatcaaa
   132721 ggtagagtgg atagcttaaa tcaacagatt actgatttaa ctggtcaagc taaaacgcta
   132781 caagacaagt tagatgctct gaaagaagaa atttctaagt taggtaactt acaagtgatg
   132841 tacagtaaca gcatcgactt cggggactat gattattcgg agaacccgaa tttaatgcca
   132901 tatattacag aaccttgggt tggacctttg ttaggtaatg gacatacagt taaagatagt
   132961 gttaaaaggg ttataactca tactaaaact agaacagcta attccggcga catattatcg
   133021 cttggcttag gtattccgtg tacagcggaa gctaataata ggtatcttat aaccacttta
   133081 cgaccatcta cgacatacac attaagcgtt actatgagtg tcggttcaga ttggactgga
   133141 gagaccaata ctataggggt taggcttaga tatttaaatg aacaaggtgg tatagaactg
   133201 cccattaatg cattaatacc agcaaatgta gaacgcgata aaatggtcac tcatacattt
   133261 actggtataa caaaagataa tgtaactagc ataacaaact gttatgttga aatattctca
   133321 cttaatagtg aatataaagg aacggttagt gtcagctatg acgttaagtt aaaagcacac
   133381 taccctaact tactagatgg cccttactgg ttaggtaaag ttcctttagg cgagaatatt
   133441 gctgacccta cagttgtctt tccacacaaa actagtgaat atatggttta tggtagacgc
   133501 aatacagaaa actatatcgc tgaccaaaca tataccatat caatgaaagc aactaaacta
   133561 acagttcaat cgtttgccgt gtatattgct gctggccgcg ttaaagtagg agacatgaag
   133621 cctactgagg ggttagctaa tacatgggag ttaactttta ctgtaactaa gcaacatata
   133681 gatagtgggg taactaatta tctggaaata taccaatacc cgtcagctac aaaaggagct
   133741 gttcaaattg agtggctcaa actagaaaaa ggcaatactc gaaccccgaa tattagtgag
   133801 tataaatatc gtggtactgg tatgcgtgat tcaaacaatc caaaagatta tgtttgggat
   133861 ctagcaccag aatatgtcga agataatttg gccacagata ttaaaatttc tgaaattact
   133921 ggtaaagcaa acaattatac cgatgggaaa gtatcggaga ttaattcgca gttgactgct
   133981 tcaattaatg aagtagacac cacagctaag gatgctcaaa caaaagcgaa tgctaatgcg
   134041 actgctatag atgaattaga caataagatc gatgaacgca ttaatgatac agctactacc
   134101 acattaacag ttacaaacgg gaataccgga tcagcaaagc tttatcgtga aggaaaaaca
   134161 gtttctatat attttgtggc tttaaacgga aaaagcagtg gtggaaatga ttcaacgata
   134221 ctaacaattc cagaaggcta tcggccacca attagttttg agcaactggt tggctcgata
   134281 gaccgttcta ctttgaacag tgctcagtta tctattggtg cagatggagc cattaaatgg
   134341 cgaagaaact caagttatgg atcggattat acctttgcaa ttacttacac gatttagaaa
   134401 agcgtgaatc gatatgaagg cagcatatag accaattgaa ccttacggat tcgagcaaat
   134461 cattgtgaat gatgaagaac atttaccgga agaatgcaca gaagtcgaac caccgattcc
   134521 aaattggaaa ccgaaattca attactggga gggaaataaa tgaaaaacat ttggaaatat
   134581 ggacgtactg gcggagagta cgcaggaaaa gtattggacg acatgcttgt atccgttcct
   134641 tacacagatc agccaccgct tgaaggaatt cgtgctgatg gcgaaccgtt aacaatcgct
   134701 gatcaaatgt ttgatcctaa attgaatcaa tggattattt tagcgaacgc actagatcac
   134761 aacgatttaa acaatctcaa agcaatgtat gagtcgttag aaaatgagaa cggcgattta
   134821 aaacagatca atgccaaact catgctaagc gatgtagcaa ttaaacagga aaatactgca
   134881 ttgaaagaaa aagcggatag tttagcacaa atcaattcaa aaatgatgct tgcttcgtta
   134941 caaaatagca aagacatttc agaaattaaa gagcaactaa atccagcttc aaagggaggt
   135001 gagtagtatg tttagtttta gcgatgtgaa aatgatgtat gattggggct gtttcactaa
   135061 cgaacaagta atggttttcg ttccgttgtg cattactgaa gaaaaagcag ataaaatcat
   135121 tagcaaagaa gagagcgcat cttaattgat gtgcttttta ttttgattca aggagttgtc
   135181 acatgattaa tttaggggaa tggggagcga tagcaggatc aataaccgct atcgtttctt
   135241 tgattttatt agtaataaaa ccaattactg catctttctc gaagattact gagactcttt
   135301 caaaagtaag tcacaattta gatttgctga ctaaagattt agaatcgagc aaatcagatc
   135361 gattgatgat tcatgaagaa ctaaagaaac acgatgaaag attagataca catgcagaaa
   135421 aattggtaga acacacgcaa caaattaaaa ctttatttag ggagagaaga aaatgaataa
   135481 taaaacgttc gaagtactaa aatggttcgc actggtaatt attcccgcac tagctacttt
   135541 cgtggggtta gttggtaaag cgctcaattg gcagtacaca gatatctgtg ttgtcatcat
   135601 tactggtttt ggcgcgtttt tagggagtgt gttgggtgta tcaaatcgaa cctacaaaat
   135661 gttctcggct gaaagcgaag aaggaggaaa caaatgaaaa agaaaattac tattactgcg
   135721 atgagcctgt taacggctct ttttttatta cccattaata cgtttgctta tactattaat
   135781 gacgagtata atttagcgcc gaatcaagga gactccagat tagcaattcc taacaaaatt
   135841 attttgcacg aaactggaat agatgcacca gcaagaaacg tagccgccaa catgaaaaat
   135901 aattataacg gaagcaattc ttatactaca gatgttattg gtgacggtgg gattgtttac
   135961 cgtgtgggtg agcaaggata tgtttcgtgg ggagctggta acgctaatcc ttatgcgcct
   136021 gtacagattg aattacagcg cacatatgat aaagcattgt ttgaaaaaaa ctatcgagct
   136081 tatattgaat atacaagaga tagtgcaaaa aaatatggaa ttccattgac tcttgatcaa
   136141 ggaacttctt tatttacaaa aggaatcatt tctcatttgt gggtgacaaa ttatgtttgg
   136201 gggaaccaca cagatccata tggttactta tcgcaaatgg gagttagcaa agaaaagctt
   136261 gcttatgatt tagctcatgg atttaccgat gaaaatccaa caacttctga aaacaagcct
   136321 gtcattgatc caacacgagc tggtgcagct aatcctacgc tgacagatgg aacaaatcac
   136381 gcccacattg atcagtttgg ggaaatcgaa aacgcaaact tgcatgtggc tggatggcac
   136441 attgctaact ataaatacga gtatattttc attatggact acaatactgg gaaagaatta
   136501 gctcgagtaa gagctgatgg aatttataga ccagatgtaa accaagctta taatacttct
   136561 ggaaatgttg gttatcatgt atctttcaat atgcgtaatt ttcctagtaa gaaagtctat
   136621 gtaatgatgc gggcaacgaa tgatccagag ggaaacacta aaggcggtgc gcaagatttc
   136681 catgacaaac gttggtattt aaatattcct aaacgataaa aatagctcct cgttgaggag
   136741 cagtacataa ctatattgac aactataaaa attattcgat aaaatagtga tgttatcgca
   136801 tatcttcact atcacccata aatagtcaca ctccaagcta tgcgataaca ggtttgttgc
   136861 cacacattct actggttgat tgtttatggc tttatgtggc aacaaccagt acccttagct
   136921 cagttggtca gagcagacgg ctcataaccg tccggtcgta ggttcgagtc ctacagggta
   136981 cattaacgta gccatttgaa tcgttctgtg ttagaatttt tttgaagagt attatacaag
   137041 ctaaagcttt tcttcattgc cactcaaatg agtggctttt ttatgtatcc ttttatggat
   137101 taatgaaagg atgtttcaca tagttatact tctgtatatt tgaaaagttt tactttgatt
   137161 tttaaataga aagacatttg ggttaaattg tgagataata ataaagaaga gtttaaagcg
   137221 caccccaaac cacttcccca taagtgtgtt acgctttaaa ctcttttata tttgaagcca
   137281 ttaaaaagca taccatattt ttgaaaaaaa gtgagaaaaa aggcttacaa ttggagtggt
   137341 agttaattag tgacttattt ttgattttat agcactgata ctataaaata tagatatcat
   137401 catattacac aatcttaata ctaacttaaa aaatatctcc tttcacaagt atggtgataa
   137461 aattcgttcc gggctacctt tttaggtagc ctactttaat ctttatacct ttctggatca
   137521 acgaaagtat actttatata gtcataacgc cgatgatcgc tacgtgcgtc cggcacgtca
   137581 gtc
//
LOCUS       DAYNVV010000003        87392 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.003, whole genome shotgun sequence.
ACCESSION   DAYNVV010000003 DAYNVV010000000
VERSION     DAYNVV010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 87392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 87392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..87392
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.003"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(62..388)
                     /locus_tag="ACGXWR_000307"
     CDS             complement(62..388)
                     /locus_tag="ACGXWR_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801926.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(761..1962)
                     /locus_tag="ACGXWR_000308"
                     /pseudo
     CDS             complement(761..1962)
                     /locus_tag="ACGXWR_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            2079..2594
                     /locus_tag="ACGXWR_000309"
     CDS             2079..2594
                     /locus_tag="ACGXWR_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFK0801927.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(2793..3239)
                     /locus_tag="ACGXWR_000310"
     CDS             complement(2793..3239)
                     /locus_tag="ACGXWR_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFK0801928.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(3286..4764)
                     /gene="msr(C)"
                     /locus_tag="ACGXWR_000311"
     CDS             complement(3286..4764)
                     /gene="msr(C)"
                     /locus_tag="ACGXWR_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFK0801929.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(5118..5747)
                     /locus_tag="ACGXWR_000312"
     CDS             complement(5118..5747)
                     /locus_tag="ACGXWR_000312"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFK0801930.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(5731..6195)
                     /locus_tag="ACGXWR_000313"
     CDS             complement(5731..6195)
                     /locus_tag="ACGXWR_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFK0801931.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(6682..7950)
                     /locus_tag="ACGXWR_000314"
     CDS             complement(6682..7950)
                     /locus_tag="ACGXWR_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFK0801932.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(8181..8918)
                     /locus_tag="ACGXWR_000315"
     CDS             complement(8181..8918)
                     /locus_tag="ACGXWR_000315"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFK0801933.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(8985..9554)
                     /locus_tag="ACGXWR_000316"
     CDS             complement(8985..9554)
                     /locus_tag="ACGXWR_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFK0801934.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            9682..10554
                     /locus_tag="ACGXWR_000317"
     CDS             9682..10554
                     /locus_tag="ACGXWR_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFK0801935.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            10896..11768
                     /locus_tag="ACGXWR_000318"
     CDS             10896..11768
                     /locus_tag="ACGXWR_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFK0801936.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            11765..13723
                     /gene="nagE"
                     /locus_tag="ACGXWR_000319"
     CDS             11765..13723
                     /gene="nagE"
                     /locus_tag="ACGXWR_000319"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HFK0801937.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(13974..14825)
                     /locus_tag="ACGXWR_000320"
     CDS             complement(13974..14825)
                     /locus_tag="ACGXWR_000320"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFK0801938.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            14948..15415
                     /locus_tag="ACGXWR_000321"
     CDS             14948..15415
                     /locus_tag="ACGXWR_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFK0801939.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(15678..16160)
                     /locus_tag="ACGXWR_000322"
     CDS             complement(15678..16160)
                     /locus_tag="ACGXWR_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFK0801940.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(16260..17123)
                     /locus_tag="ACGXWR_000323"
     CDS             complement(16260..17123)
                     /locus_tag="ACGXWR_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFK0801941.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            17721..18569
                     /locus_tag="ACGXWR_000324"
     CDS             17721..18569
                     /locus_tag="ACGXWR_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HFK0801942.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            complement(18740..19081)
                     /locus_tag="ACGXWR_000325"
     CDS             complement(18740..19081)
                     /locus_tag="ACGXWR_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HFK0801943.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            19167..19874
                     /locus_tag="ACGXWR_000326"
     CDS             19167..19874
                     /locus_tag="ACGXWR_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFK0801944.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            19861..20184
                     /locus_tag="ACGXWR_000327"
     CDS             19861..20184
                     /locus_tag="ACGXWR_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFK0801945.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(20273..21310)
                     /locus_tag="ACGXWR_000328"
     CDS             complement(20273..21310)
                     /locus_tag="ACGXWR_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HFK0801946.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(21757..22740)
                     /locus_tag="ACGXWR_000329"
     CDS             complement(21757..22740)
                     /locus_tag="ACGXWR_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase"
                     /protein_id="HFK0801947.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            complement(23156..23926)
                     /locus_tag="ACGXWR_000330"
     CDS             complement(23156..23926)
                     /locus_tag="ACGXWR_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0801948.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(23919..24854)
                     /locus_tag="ACGXWR_000331"
     CDS             complement(23919..24854)
                     /locus_tag="ACGXWR_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0801949.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(25448..27097)
                     /locus_tag="ACGXWR_000332"
     CDS             complement(25448..27097)
                     /locus_tag="ACGXWR_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFK0801950.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            complement(27292..28188)
                     /locus_tag="ACGXWR_000333"
     CDS             complement(27292..28188)
                     /locus_tag="ACGXWR_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFK0801951.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(28181..28861)
                     /locus_tag="ACGXWR_000334"
     CDS             complement(28181..28861)
                     /locus_tag="ACGXWR_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFK0801952.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(28862..29644)
                     /locus_tag="ACGXWR_000335"
     CDS             complement(28862..29644)
                     /locus_tag="ACGXWR_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFK0801953.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(29637..30554)
                     /locus_tag="ACGXWR_000336"
     CDS             complement(29637..30554)
                     /locus_tag="ACGXWR_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFK0801954.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(30557..30841)
                     /locus_tag="ACGXWR_000337"
     CDS             complement(30557..30841)
                     /locus_tag="ACGXWR_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801955.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            complement(31669..32790)
                     /locus_tag="ACGXWR_000338"
     CDS             complement(31669..32790)
                     /locus_tag="ACGXWR_000338"
                     /inference="COORDINATES: protein motif:HMM:NF019371.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HFK0801956.1"
                     /translation="MAKLKLQLEEEERVNQVSEELSEEIKDLCKKAKNKEIFSITDQI
                     KYARFKGIEISESDESIVQDILLYRTYYFKVTAYRKNFEKDINGKYIDLSFVKLADLA
                     KIDMYLRMILSRMIFELEHSLKTLIISSITNSLTEDGYKIVEDYDMYMQNKFIDSQRK
                     KGNTKTNEEILSEYTQASEKILDKVKGKFGYDFDFYNHHHDKISIWALLEVMTLGNLE
                     RFITFYFEEEHFGYLGLKTAQKLLKYVTNVRNASAHSRPLIYNIVEPYQFGRADSNLK
                     KRRPVIQLTQFATNAGLDSELIARALTNMKMNDIVATIYLHEKYVQTQKLKTTNFEAL
                     SDLLDRIKVNGKMYEKNHELVEVFHFFEKIVMEYGKLIT"
     gene            complement(32840..34456)
                     /locus_tag="ACGXWR_000339"
     CDS             complement(32840..34456)
                     /locus_tag="ACGXWR_000339"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HFK0801957.1"
                     /translation="MSNASEITAKLWAMANKLRGTMDASEYKNYILPFMFYRYLSENQ
                     DEYLEKNGLDEYYEVTDSEEKEDYLEEISRGIGYAIAPEYTWEQLVSKIENHQIKASD
                     FQDMLDSFNLNAKRNPVAEDDFANVFSDINLGDTRLGSNTNERAKALNDVVLMVNDFT
                     FKDDSGHDILGDVYEYLIGQFAANAGKKGGEFYTPHEVSQVLAKIVTKDAKADDTQFR
                     VYDPAMGSGSLLLTVKNELPDGNKQGSVDFYGQELNTTTYNLARMNLMMHGINYRNMN
                     LKRGDTLDADWPFAEKDGMQIPLKFDAVVANPPYSAKWDIKNVDREKDTRFKGYGVAP
                     ASKADYAFVLHGLYHLDKTGTMAIVLPHGVLFRGASEGRIRKNIIDNNLLDTVIGLPA
                     NLFYGTSIPTAVLVFKGRESRRTKDILFIDASSEFVKGKNQNKLSPENIDKIIETYEK
                     REDVEKYAHVATLDEIKENDYNLNIPRYVDTFEEEEVTPLPHLAQELADVKQEIEKST
                     DKLFEMLGELHGTTDEAQEELRKFMEMLGR"
     gene            complement(34472..35686)
                     /locus_tag="ACGXWR_000340"
     CDS             complement(34472..35686)
                     /locus_tag="ACGXWR_000340"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFK0801958.1"
                     /translation="MSNEITKEPEIRFDGYEGDWEERKVGEVFSERSERSGEGELISV
                     TINSGVVKASELDRKDNSSDDKSNYKKVEVGDIAYNSMRMWQGASGYSPYNGILSPAY
                     TVIIPKKDIDSKFFAYDFKRYDMIQTFKRNSQGLTSDTWNLKFPTLKSVKVMVPSIEE
                     QKQISTFFESLDTTITLHQRELDLLEQTKQTYLKKMFPKTGEDKPEIRFAGFTDAWEQ
                     RKLGEVATRVTRKNKKLESTLPLTISAQFGLVDQNTFFNKQIASKDVSGYYLLKKGEF
                     AYNKSYSNGYPWGAVKRLDKYDMGVLSTLYICFRPVDINSDFLASYYDTDRWYKEVSK
                     HAAEGARNHGLLNIAASDFFETELMIPKNNNEQEKIADFFKSLDTTITLHQRELDSLK
                     EMKKTLLQKMFV"
     gene            complement(35683..36684)
                     /gene="rhuM"
                     /locus_tag="ACGXWR_000341"
     CDS             complement(35683..36684)
                     /gene="rhuM"
                     /locus_tag="ACGXWR_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010621011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RhuM family protein"
                     /protein_id="HFK0801959.1"
                     /translation="MNEIQFLIYEDSDKVEVLIREETIWATQKTISQLFDVGVPAISK
                     HLKNIFESGELDEEVVVSILENTTQHGAIDGKTQTNKVKYYNLDAIISIGYRVNSQKA
                     TKFRIWATDILKDYIQKGFKIDVERMKQGENAFGKDYFRELLETVRSIRASERRIWQQ
                     ITDVFAEISYDYDKNSEITKQFYATVQNKFHYAITGKTAAEIVFNGADKTKENMGLTT
                     WKNSPDGRILQSDVSVAKNYLSEKQIRSLERNVSSYFDYVERLLEDETLLGMEDFAKS
                     IDEFLTFNRYQILDGNGKISSKAAKRKAVDEYKEFNKHQHIVSDFDKEITKIEGELK"
     gene            complement(36691..39765)
                     /locus_tag="ACGXWR_000342"
     CDS             complement(36691..39765)
                     /locus_tag="ACGXWR_000342"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002898492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009035 - type I site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HFK0801960.1"
                     /translation="MTKQFGIKSQSELRFEQEVVDYLTRIGGVKQWEYKAEIKTTEQL
                     WNNFKKILEQNNQARLDEPLSATEFNQVKKIITNINTPYQAGQFLYGVNGVSEIEVDL
                     DNGKHVFLTVFDQAQVGGGNTVYQVVNQIQRPKVVDGKPNRRFDITLLINGLPIIQIE
                     LKKALHNATEALNQMEQYIAEKQFSGIFSTLQILIAMTPFDIRYMANTTLQNFNRAFA
                     FNWQDEETAHPVRSWKLFADKVLSIPMAHDLSTRYMVLDGTKNKESIKVMRPYQVYAT
                     KRVLDKVRKFDFKHDEGKLGYIWHTTGSGKTITSFKTAWLASRLSNVDKVIFLVDRIA
                     LTNQTADAYRAYDPIAGFEGKTGVVSDTANISDLHRKLTKKSDKNIIVTSIQKMSRYV
                     TRDSFQPLTENVLFIVDEAHRSTGDGTKNEGMLESIRKALPNSAWVGYTGTPKFPETR
                     EIFGDLLHAYTIKEAIADKNVLGFKVEFKETIEAPADPTEEDIDDNLRGSVYDHSPEH
                     VELVVEDIFDNWKERSNNRKYNALFTVHVGGNRASTPRAMEYFDKFMEENNKRSIEDQ
                     IKVAISFSMDTSNSSHQLKTNENLHRAIQSYNRLFGTAFDMTTVKSYTEDLARRLNKT
                     ADDGNYLDLVIVVDQLLTGFDAPELNTLYIDRTLKGGNLIQAYSRTNRIHDRDAKPQG
                     NIVNYRWPIQNEYEMNKSFAIYSNRDSAAEQLSLDELKKDNEESGILSKSFSKIESET
                     KEVIQKLAELTDNFIQLPPSEKAQEEVFEGLQEYNRLLNQLKQFTEDDEKNPVSVYDE
                     PELFYDRLGITEDQEVMLTTVLANELRERRAQIENIDISQVNLEMTHIHDVTINYDYL
                     IELIARMADEVHEDKMDQAELTKNEIDVEIAKSDSDKEITKVRNFVSKIFTKEFIFDK
                     YPAPRDVEEMNQAMEQSQKDSNIKLYTEFVRTWGLDNSVKPKDLAKLISRHRVGQEDM
                     DKQGELTAMMNDARTDYKEIAAAEVANLSWVKYRIEFRKAFYQMADETKKGE"
     gene            complement(39769..40347)
                     /locus_tag="ACGXWR_000343"
     CDS             complement(39769..40347)
                     /locus_tag="ACGXWR_000343"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFK0801961.1"
                     /translation="MEMRKLSEFVTFVQGINQSRAEKQFGNQEIDYYDQASFEEDHKY
                     YNEATQEERVNYLFDQEVSLDKRDVVISNSLQRATMVSGQNVGKVLSLNFTKVEFKSD
                     LLDKRYFLYLFNNHKDIQRQKDRGLQGTGPVLRLTKQSLEQLVIPLPLIEEQRKIGGI
                     YTESLKLQSKLSIYTRLLEQFTNSMLEKSLEE"
     gene            complement(40650..40895)
                     /locus_tag="ACGXWR_000344"
     CDS             complement(40650..40895)
                     /locus_tag="ACGXWR_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFK0801962.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRIRLEKGIGQTELIRDLQLHKIA
                     ITRETLVKIEGGRQHIKLDQLRAIRDILQVSYEDLLQ"
     gene            41000..41773
                     /locus_tag="ACGXWR_000345"
     CDS             41000..41773
                     /locus_tag="ACGXWR_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801963.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSETSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAKLYTEKVEQFFKSGANKDFSKISDYSENFFNETQDEIMNSTFMA
                     EDMYNMTLKKIKAYDHPLNLTLNNGLLSFVLAGYVDYEYSPDYLEKPLQHENNDINFR
                     FVYESKSKTWLVDQLSTINTSFHELPKPENEVEMVIKIF"
     gene            complement(42003..42206)
                     /locus_tag="ACGXWR_000346"
     CDS             complement(42003..42206)
                     /locus_tag="ACGXWR_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prevent-host-death protein"
                     /protein_id="HFK0801964.1"
                     /translation="MLQEVVHSNSEIEITRDSKNGLNDGVIMISKRKWELLQEELYLQ
                     RTGTWAYVSDLMKNEKEDDFKVV"
     gene            42287..43413
                     /locus_tag="ACGXWR_000347"
     CDS             join(42287..42515,42515..43413)
                     /locus_tag="ACGXWR_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFK0801965.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAGSHILSENLNSLVQFIEKWCKDYTVS
                     LLCRLLEIPRSVYYFYKNKPLTATEIRNNTLKKKISTIFFTNKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRSNKPIISKENLLNQDFSTETICEKWAAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMIL
                     HTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDF
                     EEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEKMA"
     gene            complement(43601..43915)
                     /locus_tag="ACGXWR_000348"
     CDS             complement(43601..43915)
                     /locus_tag="ACGXWR_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801966.1"
                     /translation="MTEENKVDLLETLVINKKEFEQLFLDFFVQYDRIYDFNSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSETFEIDADYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            complement(43992..44486)
                     /locus_tag="ACGXWR_000349"
     CDS             complement(43992..44486)
                     /locus_tag="ACGXWR_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801967.1"
                     /translation="MFKVYFPFQWLVKGIFFVLLGLILFGSYLTIKARYFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIELTEKRNEFAQHDRVLQVTYTMKNDTENPIRPQQW
                     SIENKDGEELYEYAMILDNPEYIESGKSETVNYYYELPIERQDYQIVVRRANGYFVGL
                     PFNL"
     gene            complement(44479..44781)
                     /locus_tag="ACGXWR_000350"
     CDS             complement(44479..44781)
                     /locus_tag="ACGXWR_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801968.1"
                     /translation="MSDPYIKVYCSKETKKLFDSFYEKNKGTLGTKANMFRVMVSNLP
                     MLASQSNKKFSDPESIKLEQTISELESSIMKKLDGIDQKLSCSLKTKYKTEEKKDV"
     gene            complement(44804..46141)
                     /locus_tag="ACGXWR_000351"
     CDS             complement(44804..46141)
                     /locus_tag="ACGXWR_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFK0801969.1"
                     /translation="MGSIIKIASKSRSIHNTISYMLNKQEDSELVTGIGVSNDLNAIE
                     EFKRTNEIFGDKGKIKLWHFTQSFDPLEDISAEKAHELGVKWAEKMFPNQSILVVTHT
                     DKGHVHNHFGISPNDQRTGKKMDIRKNDIRVLQAWNDNILIDNGINPLDMYKYNHLVA
                     DRENWKEREFRTENKISNREKIKLAVSEVAQYAKNYDDFHAELKKNHSIETYRFAKNQ
                     RIGYKLLDSEDGLILKIGGKRLGQNYDMNYLDDLFTENKKAEQIQSEEVLTEIAIRYL
                     GKSLNGRADSRFNWQERAQRFELDNENIPFLRSSKDYEEFYDKYKFEIEDRIENLLDV
                     FGENKNQFFGFAVEEEPLKYKKKCVNLVYKKVVYDIAESLSTDYDQFNIQDTEPALKR
                     NFKKRYIQETKRVLYLFNRAIDDGTIEKARREYEETARGIDYQKQQNQYDMDF"
     gene            complement(46126..46623)
                     /locus_tag="ACGXWR_000352"
     CDS             complement(46126..46623)
                     /locus_tag="ACGXWR_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801970.1"
                     /translation="MAIDVSKLPLEERRKRYKRNEDSRRQNRPIKFRVDDYQYQELEK
                     TADIFGLSVPMYVKKIAVDNAGKSLKYTDRQYKEINFHLLAIGRNLNQLVKTANYLRV
                     QLNKKDTEIQKEEHQSVYLSFTTKQERLKRLYAEKNDLMIQIKSISDPLNRLEKELNK
                     LWARL"
     gene            complement(46772..47110)
                     /locus_tag="ACGXWR_000353"
     CDS             complement(46772..47110)
                     /locus_tag="ACGXWR_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801971.1"
                     /translation="MARKKQKSIADLKKELAELERKLYPELGKYVYEKTGISSVKEFE
                     ETFEINQKGTQEKWQKAVNFANSEFTLVHEFLASDQLMETKFQQFLRRKGETAYRIFY
                     REEAQEESVR"
     gene            complement(47114..47299)
                     /locus_tag="ACGXWR_000354"
     CDS             complement(47114..47299)
                     /locus_tag="ACGXWR_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801972.1"
                     /translation="MQLILQISTQDFLELAELCDSVKKATNEKITVTNYIELMIQEEL
                     VMKNELMNELSHIQKGA"
     gene            complement(47313..50066)
                     /locus_tag="ACGXWR_000355"
     CDS             complement(47313..50066)
                     /locus_tag="ACGXWR_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFK0801973.1"
                     /translation="MKIIKKKIDNRKINWLLISFLILIAMIIFTSNVAEGSIFNWFDD
                     TESQTEFLTNPLYQNYLKKYNGNFYSQFGMWIGWSVIKSMFAIVDGIQNMIPEVLDLF
                     SFVESTGLNKVYQSVLSTIVVGLMILSLVIIGYKMITGKGTVDLKSVGMNVVMSVALI
                     LLMPTLIHSGIEFSKTFYNDTTTITNSDEGVAWSLIEQGVTDLAYINKTDQYSMINKT
                     NDRNNLTKENFWKTDLTQVLTDNVIDKMEKENPTADNLRYELVENSDNEFVATKFSDN
                     FLSTFVDGIKSGYYRYQANLWGISFGLIALAVAYVFSAFIIITAILELAFKRVLGVLV
                     FATDLETGQRSKQVLSDILQCYLTVGFQGFGLSMFAMFVNYLNAGEGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGTGGMNRSKGGKN
                     SGGNDQAEGEERKPERNFGQSLSQKANKTGKTLGYARERRLSGLASDGATMASERATK
                     PFKSMRDMANDTKNKFKEGLDDGTMSAINKNSKPIVAKNKEDETGKYADSMPTRLSDR
                     KDGAKVENADRIMSSSERMREAMKNNAESNINPASAIQQKVKQDIEERKNAMHGQAKS
                     AEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGANMDEKEALTKERIQEAKNSNTGL
                     EKSVKENPQNSTSSQDRRSVDVRENLQNTTSSQNGNRTVDVRENVQSSGTSQPRTVDV
                     RENLQNTTSSQNGNRTVDVRENVQSSGTSQPRTVDIRENLQNTTSSQNGNRTVDVREN
                     VQSSASNQPRTIDVRENLQNTTSSQSGNRTVDVRENVQGSASNQPRTVEVRETRAEAS
                     QGDKTQKINIVEERKERPNEKVIVEQEVKEKKRQRFTYENNPLFQDISDKPNPLFDSL
                     FKK"
     gene            complement(50053..50271)
                     /locus_tag="ACGXWR_000356"
     CDS             complement(50053..50271)
                     /locus_tag="ACGXWR_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801974.1"
                     /translation="MIENHLVDKIYCLDHNADTLELIESICSNTIVLDLRAVNDDYVT
                     HIIVNKKMAQKLSESLKKWAEGGNNENN"
     gene            complement(50264..51004)
                     /locus_tag="ACGXWR_000357"
     CDS             complement(50264..51004)
                     /locus_tag="ACGXWR_000357"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801975.1"
                     /translation="MREKLKKLGDKKRHTFQGTFEFNGYKKDKYKFGQEYENATFMLS
                     NLKIVQGDNLELVTDHIWMNLTKQFLKFGWLKKGDMVQFDGRIKSYSSKKGINYKIER
                     PSKVKVFRKGTEINESSALKISTRYEIVEDIKRQNREYYEARDFFFENYFSVPRYFKL
                     KEKWPEIQAVVAINENRYTSEQFKQVFKDRDSLVDLYKKIQETDKYNLQKEFYNGLVS
                     NKNRIDLNEVEGYLHKIENFDYGRGYFD"
     gene            complement(51137..52012)
                     /locus_tag="ACGXWR_000358"
     CDS             complement(51137..52012)
                     /locus_tag="ACGXWR_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
                     /protein_id="HFK0801976.1"
                     /translation="MAEKRMLAKSFLNNASFMKMSDSAKLLYVYLNTNADDDGIVEAY
                     PYTKMLGTPDDDVKILFTKGFVFFLNEDLLAFLPHWLQNQNIRIDRYKPSIYRFKLLN
                     LKPEFFSKLKPIKFDMILQSGQVEPLRVDLMEKWYPAGIPCDVKSDTQLSQDQNSQDQ
                     TNQDKDSIEEINQDQNSFFENIINQKGIQIITRLGDRYTEVQREKYLKLIASMKDSIE
                     REYKIEIRGQDYFDITNKMLTRLFNSINEKLNLGEEIDEMKFINTTARNHWEDIAKQE
                     KASRLDMLETLKKIG"
     gene            complement(52182..52463)
                     /locus_tag="ACGXWR_000359"
     CDS             complement(52182..52463)
                     /locus_tag="ACGXWR_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0801977.1"
                     /translation="MEQIGVSVMLNTDQTNQLKTHVFEVTKEAIDQARIDSGLERPFL
                     KGKEMAKFLNVSYGTFLKFKRLGLPIIVVDTIELYSKEEVKKWMLQHQI"
     gene            complement(52518..52715)
                     /locus_tag="ACGXWR_000360"
     CDS             complement(52518..52715)
                     /locus_tag="ACGXWR_000360"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFK0801978.1"
                     /translation="MFQINEDFSIRIRERRGKLMITKTKAAELIGISRQTLKKIECFE
                     VQSVSKNVYQKIIGWLLKSDY"
     gene            52882..53256
                     /locus_tag="ACGXWR_000361"
     CDS             52882..53256
                     /locus_tag="ACGXWR_000361"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0801979.1"
                     /translation="MTQKNRIKETREEQNLTLKELSNLSDIPYQTLRNYEIGKRKPRN
                     DEVWWKLGTILNVRGPYLKGEDSFKTNDELHIYYLKKSHTNFELSKKEEIIDIIDKLN
                     EDGLDEALRQLALLSKIDDFKR"
     gene            53346..54512
                     /locus_tag="ACGXWR_000362"
     CDS             53346..54512
                     /locus_tag="ACGXWR_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFK0801980.1"
                     /translation="MSIQKYKTKSGTRYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDMGYHRPSNDLFRTVYEEWLPSYKNRVQETTYQRTKDLFRLHILPKFG
                     DKSISKITPIYCQNAINEWAVKYTNIKQLKSYSSQIFEYAIFAELLQRNPMTNTKLPK
                     QEKKESENYFSLEELKEFLEILNKEESLKHILIFQLLITTGVRKGELSALRWADINFE
                     EQLLHIGKSYATIRTEDPNATRKTIRIQKNTKNVSSERILPIDTQTIEMLKLWKKEQA
                     EVLLQFGINANTKKQLIFTYVNANGDVNQPLHADYSNNIMRRLEKKYKFKHVTIHGLR
                     HTHATLLLEGGASIKEAQDRLGHKNAETTLNTYSHVTEKAQRNAVDKFIAYTGL"
     gene            complement(54611..55003)
                     /gene="rpsI"
                     /locus_tag="ACGXWR_000363"
     CDS             complement(54611..55003)
                     /gene="rpsI"
                     /locus_tag="ACGXWR_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFK0801981.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(55019..55447)
                     /gene="rplM"
                     /locus_tag="ACGXWR_000364"
     CDS             complement(55019..55447)
                     /gene="rplM"
                     /locus_tag="ACGXWR_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HFK0801982.1"
                     /translation="MAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPTFTPHL
                     DTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLIETSVK
                     GMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(55981..56448)
                     /locus_tag="ACGXWR_000365"
     CDS             complement(55981..56448)
                     /locus_tag="ACGXWR_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFK0801983.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(56568..58106)
                     /locus_tag="ACGXWR_000366"
     CDS             complement(56568..58106)
                     /locus_tag="ACGXWR_000366"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046316 - gluconokinase activity [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HFK0801984.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            58186..58872
                     /locus_tag="ACGXWR_000367"
     CDS             58186..58872
                     /locus_tag="ACGXWR_000367"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HFK0801985.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(59073..59600)
                     /gene="msrA"
                     /locus_tag="ACGXWR_000368"
     CDS             complement(59073..59600)
                     /gene="msrA"
                     /locus_tag="ACGXWR_000368"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFK0801986.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(59684..60361)
                     /gene="pgmB"
                     /locus_tag="ACGXWR_000369"
     CDS             complement(59684..60361)
                     /gene="pgmB"
                     /locus_tag="ACGXWR_000369"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFK0801987.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(60358..61488)
                     /locus_tag="ACGXWR_000370"
     CDS             complement(60358..61488)
                     /locus_tag="ACGXWR_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFK0801988.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(61488..63671)
                     /locus_tag="ACGXWR_000371"
     CDS             complement(61488..63671)
                     /locus_tag="ACGXWR_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 65 protein"
                     /protein_id="HFK0801989.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(63668..64693)
                     /locus_tag="ACGXWR_000372"
     CDS             complement(63668..64693)
                     /locus_tag="ACGXWR_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFK0801990.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(64738..65565)
                     /locus_tag="ACGXWR_000373"
     CDS             complement(64738..65565)
                     /locus_tag="ACGXWR_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFK0801991.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(65562..66629)
                     /locus_tag="ACGXWR_000374"
     CDS             complement(65562..66629)
                     /locus_tag="ACGXWR_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HFK0801992.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKHGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLIGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(66655..67491)
                     /locus_tag="ACGXWR_000375"
     CDS             complement(66655..67491)
                     /locus_tag="ACGXWR_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0801993.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(67488..68357)
                     /locus_tag="ACGXWR_000376"
     CDS             complement(67488..68357)
                     /locus_tag="ACGXWR_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0801994.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(68427..69710)
                     /locus_tag="ACGXWR_000377"
     CDS             complement(68427..69710)
                     /locus_tag="ACGXWR_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFK0801995.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(69724..71409)
                     /locus_tag="ACGXWR_000378"
     CDS             complement(69724..71409)
                     /locus_tag="ACGXWR_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFK0801996.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            71684..72709
                     /locus_tag="ACGXWR_000379"
     CDS             71684..72709
                     /locus_tag="ACGXWR_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFK0801997.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(73304..76957)
                     /gene="rpoC"
                     /locus_tag="ACGXWR_000380"
     CDS             complement(73304..76957)
                     /gene="rpoC"
                     /locus_tag="ACGXWR_000380"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HFK0801998.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(77036..80653)
                     /gene="rpoB"
                     /locus_tag="ACGXWR_000381"
     CDS             complement(77036..80653)
                     /gene="rpoB"
                     /locus_tag="ACGXWR_000381"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFK0801999.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            81381..82349
                     /locus_tag="ACGXWR_000382"
     CDS             81381..82349
                     /locus_tag="ACGXWR_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFK0802000.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            82367..83272
                     /locus_tag="ACGXWR_000383"
     CDS             82367..83272
                     /locus_tag="ACGXWR_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0802001.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            83269..84075
                     /locus_tag="ACGXWR_000384"
     CDS             83269..84075
                     /locus_tag="ACGXWR_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802002.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            84232..85200
                     /locus_tag="ACGXWR_000385"
     CDS             84232..85200
                     /locus_tag="ACGXWR_000385"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HFK0802003.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(85517..86041)
                     /locus_tag="ACGXWR_000386"
     CDS             complement(85517..86041)
                     /locus_tag="ACGXWR_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HFK0802004.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            86328..>87392
                     /gene="scm"
                     /locus_tag="ACGXWR_000387"
     CDS             86328..>87392
                     /gene="scm"
                     /locus_tag="ACGXWR_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFK0802005.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        25556 a        18237 c        14975 g        28624 t
ORIGIN      
        1 tttttagagg ctgtgacaaa gattttgtca cagcctcttt ttccatataa acggcgttcg
       61 cctaccagct gcctggtaaa tctgtttcct cttcgttaag aagcgaaaat ccgtcaaatg
      121 tttcgccatc ataataacga agcagctcat ccatggacaa gttcatcgtt ttttcttttt
      181 cttcttccgc tgattcagcc agtagctgtt cccgatacac ctgatacata ccagctattt
      241 tttgctgcat cgcttttcta gtttcacctt ccgcattgat tattggcaat tctttgatat
      301 agccacgata aatcaaccga tcatctgaaa attcaatggg taattcaacg agtgtcaacc
      361 cgacttcctg aaaatattct tccagcatct attatccccc cattcttttt cttaaatgaa
      421 ttttagctta cctactgaaa attttccagt ttcattattt tgagaaaaaa agggaatgtg
      481 acaaaaatcg tgtcacatcc cctttttccg aataaatggt gttcttctgc caactcctca
      541 atcataagtc acaatattca acaaacatga gaaactgttt tttgaaattg ttccttgtga
      601 ttcagagtta aacgacagtc tcacaacctc ttggtaaacg gcgttcaaaa gcttgcatct
      661 gcggtaataa gcccaaccaa acgaaaaata tgagaagcta tttttgtttg gctgttctta
      721 tgacttgatg caggacagct ttttcacaac ctctgatttc ttattcttct tcatttgtag
      781 caaaataatt acggtgataa atgatacaac atacactgat aagaacaatg gcacctgcaa
      841 aataaaacgc atagctttca ccaatatgtt caccaatcac acctgcaata aatggtgcta
      901 aagctccacc gaaaaagcgg acaaaactat agctggacga agcaacgttt cgttgcagac
      961 ctggtatttc catagcaatc gtcgtcaaca gtgtattgat aattccttgg aaaaatcctg
     1021 ctaacacaat gctgatcggt acaaggactg gcatagaagt tccagctcct aataacagca
     1081 aacaaataat gaataagaca aatgctgcta aaattgtccg ataagtcgta aacttccgct
     1141 caagagccgg tgcaacgaaa atcgaagcaa tagccagaag cacaccccag ccaaaaaata
     1201 caaaaccgac ttctaattca gaatagccaa tcaataaaaa tggcgcatac gcaagtaaag
     1261 taaagaatcc gaaattatat aacaatgcga ttagtccaac tgaacgaagt ttatgattgc
     1321 ttaacgcttt gacaccttcc caaaggccta cttttctctt tggtttctca gtttcaggta
     1381 aaagtaccgc tagggctata aaaccgcaaa acatcaaaaa tgctacccca aaaaatggat
     1441 aacgccatga accactgccc aagaccccac cgactagagg gccaacagcc attccgcagc
     1501 caagtgctgc ttcatacatc atgattgctt tttctgtgtt accaactaaa atactgacga
     1561 tcgttgctaa agcagtagag acaaataaag cattcccgac accccagccg gcacgtaacc
     1621 caatcagcat tccgatattc ccagataatc cgccaagacc agcgaataca acgatgataa
     1681 acaatcctgt catcaatgtt ttttcaaacc gatccgacta gataagaaac ctgtaaatag
     1741 catcaccaca ccagtgacta acatgtaact agtaaataac agggtcgttt cagctggcgt
     1801 agcgtttaac tgtgcagcaa tcgtttttaa gattgggtct actagaccca ctcccataaa
     1861 agcgatcata caggtagctg ctacaactag cgctgaactt ttcccctttg tttcttcatt
     1921 tgtttgttct tgtatatcta tttgattctc caatatttcc atccctttct ctctattagc
     1981 atcatacatg atttatttta catgtaaata tgcacatgta aaacgtggaa actttactgt
     2041 gatataataa agaaaataag acgagaggta ggatttttat gaatacttta gcctatatat
     2101 tattatgcgt gcttttatcc aaaccacgtt ctgggtatga attgaagcag ctgatcacaa
     2161 ttttttggga agcccatcac agtcagatct atacaacgct tgccaagtta gaccagcagg
     2221 gttatgtgac cgttttggac aaagacgagc actctcaaaa aaagatctac cacttgactg
     2281 atgaaggacg tgctcttgta gaggaatgga tcaaagagga aactcccgct cctacgcaaa
     2341 aagatgaatt tctagcaaaa atctatgctt tttcgacgct cgataaaaca acagctactg
     2401 gactgctatt cactagagaa caacagctga acaaaatcat gcaaaaaaat caaaaaaaat
     2461 tgaatgacct ctcgctagac aagaaacaag aatttggacg ttatgttgtg atccagcgca
     2521 gaattatgct ttgtcagcag gaactccaat ggtgtcagca agtaagagaa caaatgcagc
     2581 agttttttga gtaagggata aacagaacct ttctagaaat atctattgaa gagcaaatta
     2641 tcttcaataa aagagcaata cagttggaaa agaaaaagcg atccgaacga caggccaaaa
     2701 cctatcgttc ggatcactat ttttctagaa ctgcattcaa gagactatga caaaaagcat
     2761 gccaaggcct tttttcaaat aacagtgttc catcattcat tactttgaat tgcttttagc
     2821 acacttcttg aaagcgggcc aacgatgatc aactgcaacg gtaaagcggc aatcacattc
     2881 attttccaag cattcatata agcagagaat aattgatcag gtattccttg ttccatgatc
     2941 acaccgaata aagacataca tgtcaccatt cctaaaacca tcaagcatga aatagttaag
     3001 atcatttgga ccttgctttc tggatttact ggtagtttaa aggcaatttt tttcgccagc
     3061 acaccgatga tgaagacatc caaaatgaaa gccaccacga atccaggcac tagaccaatc
     3121 aacaaacttg ataaatgaag atcttgatgc agccataaat tatacgcgct catccccaag
     3181 accatcaaaa aacacatcat tgttgtaaaa attattcctt cttttttatt tgtaggcaat
     3241 ctgtaccact cctttaaatt tgtcacgaaa atcatcgtag cacatttaaa aatttctcgt
     3301 aagtactttt tttattttct gcccttttat ttcataaact tcatcagccg tacgctcgac
     3361 aaagtaagaa tcatgagaag taaacaaaat cgttcccgga tatatttgca ttagcttctc
     3421 taaagcttcg atcgttgcca tatcaataaa attagtcggt tcatctaaca gcaacacatt
     3481 acttggctta gtaaaaagca aagcaatcgt cagacgggtc gcttctcccc cacttaatgt
     3541 acataacggt ttcgtcaaag tttcctgagc aaaccctaag tgattcagca aactacggac
     3601 aagcgattct gaaaactctg tttgtctcat gacaaaacga atgatggatt cttcagatgt
     3661 catttgataa cccttttgct gatatacttg aaagcttact ttcggagaga gaaggattcc
     3721 ttctccttgt ttgcggatat gttctaataa ggttgtctta cctgaaccat tttcaccgac
     3781 aatcgcgatt tttttaccta aagaaaactg aaaatcacca tttaccagta atgttctccc
     3841 acttctttcc aattggacat tttgtcccat gatgggatag cggctgtgga gttcaagaga
     3901 ttttggtact ggaaaacgga tttgtttcat ctgctgcggc ttggttgttt ctcctatttt
     3961 ttggagtctt ctctctaatg ttttcgcatt cttttggatg gctttttgta cactgtcttt
     4021 ttgtttagag gaagacaacc gatccggtct gatttgttgc tttttctttt tactggacac
     4081 tttttccaac ttttccgctt gttttttctt ttcttggatc gatttttcca atcgtttttt
     4141 ctctttcatg atcgactctg cttctcgtag ctgagtcttt ttctccaatt ccttttgagt
     4201 gagataggca ctataattcc ccgaaaactc tcggatttct ccgtctttta cttcccagat
     4261 tttcgatgct agctcatcta gaaaatagcg atcatgacta acaaaaacca gcgtaccata
     4321 ataataacga agctcttcaa tcagtcgatc aatacttttt ctatctagat gggttgttgg
     4381 ctcgtctaga agcatccctt gttcataaga agaaagaaga cgtatcaact cgatctttcg
     4441 ttcttcccct ccgctccatt tccgctctga agtttcttcc agtcttaact ggaaatgact
     4501 ggctaattcc aaatttaggt cctttgcttc agcgagatag gttaattgag gcaggtagtt
     4561 gaaggtgatc tctgtttgga ttttcccatg atcgggaaaa agttcaccgg ctattagttt
     4621 gagcaaagtc gatttaccga caccattttc tcctatgatc cctatacgat cttgctgata
     4681 gacacgaaga gaatcaatag atagttctag ctggttgcca aagctgactt gtagatttgt
     4741 tatatttact gctaaatttt ccatatgttt tacactccta tttcatgtaa aacaacaatt
     4801 atcgatacta aaaaagagca gaaaaatctg tttgcaaaaa aactgcatca catcttttcc
     4861 tactctgaac gaaataacta tgactaaatc accaaatctg tcatagcttt cacctattct
     4921 actgtcgttc gaaaaaatgg acatactcca tccatgaaat tgttgtttat acatgtcttt
     4981 tgaatttatt tagttgttat tcaaaagttc gaaacgtaat ttcatcgatg cagtcatttt
     5041 tccgacctcc ttttttatta ggttaccaca cacgattcaa aaaaagcaat agctactgaa
     5101 tagtaactga aaacctttta ttcgaacgta gtgatctttt ctggtgctaa acgaacagac
     5161 tcgtaacctt cttctaccgc ttttcctatt gataaaataa taactggaac ataacggtct
     5221 ttatccaaac caaatgcctc tgccaactga tctgcttcga atccaccaat tggatttgtt
     5281 tcatagccat gatcacgcgc aactaacatg aattgcatag ccgctaagct agaatcgact
     5341 ttgactacat cgttcatttc ttctcttgaa aaactcttgt aataaggaat gatcgcagct
     5401 aattgttgat ctctgacttc ttttggcatc ttccctgatt cgtaagcttg gttatagatt
     5461 tcttcgccat attcgtaaca ttgcatatcg ccaaaaatca tgaccattgc agaagaagta
     5521 tcattttgtc tcgtattgaa acggatcaaa ggacgcaaga tttcttttgc ttcctcgctt
     5581 tcagcgacca caaagcgcca tggttgcata ttgacagaag aaggtgcagt cgtcgcttct
     5641 ttgatcattt ccagcatttc ttcgtgtggg attttgtatg tttcatcata tacgcgaacg
     5701 gatcttctac cagtcataat tgttgaaaaa tcattttttt gttccattat tattaacctc
     5761 tttcgtttct gttgttatat tgcaaagttg ggtattcaat ttatctaaaa gtgttagaaa
     5821 ttgtttcatt tctacatcgc tgaaagccgg ggatagcacg gaacctgtat ctttatggtc
     5881 catttcacaa tgctcgattt tcttctgggc tttttctgtt agcgctacat acacttcccg
     5941 gttgttctga ggatttctct gacgcgaaac atagccattt gcttccaata ccttcagatg
     6001 acgagtaact gctccttgat caatctgcaa cttttcttgc aaactgcttt gtagcaatgg
     6061 attttcttct ttcagtctca tcatgatctc gtatctagta agacttatac cgatattttc
     6121 ttcaaagatc tggacgattt tttgatcggc taatttgatt tgatataaaa ggtgactaat
     6181 ctcttctaaa gacataattt cctcctttct aataattgac tcgtcaacga ttgacttgtc
     6241 aataatagaa taaaaaaaga aaaaagtcaa agaatcagct gtgtaataaa aaaaacgctc
     6301 tcaatagaaa agtatagaga aaagaaattt tttgtagaat gaacggaaaa aatgataaag
     6361 aaagcacaac gctaaaacca agattattga ttcttatcaa actatagaag atagctcttc
     6421 tgcagtagaa aattttacac cgccaaaaat ttccgaaatc gccttttgca agaatcccgt
     6481 cgaatattag aaattggatc agtatgctta aacagtaata aaaaagttat gacaagatgt
     6541 tgtcacaacc ttttttgagt aaacggtgtt caaaaacttg catctgcggt aataagttca
     6601 accaaacaaa aaacatgaaa atctgttttt gtttggctgt tcttactact tgatgcaggg
     6661 cagctttttc actacctctt tttaataacc ataaaatcct attccttcat atctccagcc
     6721 catcggtgtt agccaatctc tttccttagc actcaaggta tagtgatggg taccagtttt
     6781 ttcatttgga ttaaatagtc gataaattgg cttggaacca ccagaataaa aacttagacc
     6841 ttcataacgc caaccgattt ttgttaaaga gttgatctca gattgtgcca ttgtgtaatg
     6901 atggtctcca ctgtaaggat tgtataaacg gtagacaggt tgtccgctgt ttggtgcttg
     6961 ccaagcaatc ccttcatatt cccagcctac agttggcaga taattttttt ctccggcatt
     7021 caatgtatat aaatgttctc ctgtatgacg gttatacaga cgatacatcg gagaagttga
     7081 agttggtgct gtatcatact gtgtcagatt ataggtttcg attacattgt tcaatgtaga
     7141 accataatta ggcgcagtgg cataacgacc tgttagccaa gccgtagcat ctttgtaaga
     7201 gttcgtattg cttttccatg caccggaata gtagtaaacg cctggctgaa aagaagtcgt
     7261 cttcaatacc gttacgttat cttgcaatga ttctttgtac gaaggatatt ttctaaaagc
     7321 ggcattcacc gtaatccatt gcccattcac atattccgaa gtaggcatcg taacagattg
     7381 gccattatag cttcctttaa tcccaaatag attgtaatta ggggcagaag ccaaagtact
     7441 gttcccccag ccactttcaa cgatggcttg agcaatcatg actgatgcat ataagtcatt
     7501 ggcacttgcc aaactttgtg cagttgaggc aatactatca atgaacgctt gttgagaatt
     7561 agcagatgag cgagcataaa aagcatagcc agtatagttt tcgaattcag acaaatctgc
     7621 ttgatgggta tgtgtcaatg tttgcccatc tgtcaattgg ttcgtgattt cttctgcatt
     7681 ctctggattg ttctgagctt ctgctgatgt actgtcttcg gtttgtgttt gttctgttgt
     7741 ttcagttgtt ggttcttcgg ttgaaattgt attttctgag acagtagctg actgcaaagt
     7801 actctctgta tcgttttcaa ttcctgtttc tgaagaactc gatgtctgag ttgcgacagt
     7861 ttctgtcgat tcttcagcta gcactgttgt gttggcaact gctagatttc ctaaaagaat
     7921 aacgctaaat aataaattct ttgctttcat cttttttctc ctttgaatta tgaaactttt
     7981 cctaaataac agtgtaacta aaaaagtaaa agcaagtcaa tgtccatatt taaataacat
     8041 ttgtttcttt ttgataaatt tgctttttct acataaaaag acgtaaatga agaatattct
     8101 tctccattca cgccttaaat tgatggtcgt ttgaataact atttaacaag taattctctt
     8161 tggatattat ccgttatgga ttatacttcc tgtgtcgtcg gacggataat catgttactg
     8221 acagacatcc ggtctggcgt ttctatcgca aatgctacag cagaagctat atcttcggag
     8281 gtcaatcccc attctttttg cgcttcatga agttcaagag cagccttttt gtcgctgatg
     8341 gtttgatata attcagtttg aacagctcct ggagagatga tcgtagattt gatgttattt
     8401 tgccgttgct cttgacgtaa tccttccatg attgcacgga cagcaaattt tgttccgcaa
     8461 taaacggcgg aatcaggata aacaacatgt cccgccacag aatcagttga aatgatatgc
     8521 ccagattttt gtttttccat gattggaagt acggcggaaa ttccatttaa cacacccatg
     8581 atgttgatat caagcatatt ttgccattca tcacggtgac cttcaactaa tggagcggtt
     8641 ggcatgattc ctgcattatt gtacaataca tcgattcgac cgaacttttc catcgctaaa
     8701 tcgataactg cttggacttg tgcaaaatct cttacatctg ctgtttgaat atatagctca
     8761 gcttctggta aagattcttt tattgctttt aggcgatctt ctcggcgtgc agctataact
     8821 agtttagccc ctttttctgc taatagcttc gttgttgctt caccgattcc gcttgaagcg
     8881 cccatgatga caatcacttt ttctgataaa tcattcattc tattctcctc ctgttttgaa
     8941 aaatctcttg cttatactca ctatctctta tttcatctta ctgttcaaat aatccgttcg
     9001 acaggtttga cgattttggc agggattcct gcaacgatgg tattgtctgg gacatctttc
     9061 gtaacagttg cattcgctgc aacaatggca ttctcgccaa tcgttacgcc tggcagaata
     9121 gttgctcctg ctccgatcca agcatttttc ttgatgtgga ttggctttac tgacaagcct
     9181 cttcgttctt ttggatcggt tagatggttc accgtgatga ggttgacacg aggaccaatc
     9241 aatactgaat cttctaaaca gatgccacct aagtcaacga acatcacttg acgattgata
     9301 aagacatttt tccctatact aatatgtttg ccgaaatctg tataaaaagg cagcagaaca
     9361 gtcaccgtat catctacttt gtcactaatg atattttcta gccgtttgcg gatatctgct
     9421 ggttcatggt acccagtatt cagcgctgct aaaggctctt cgttttcagc ttggatctga
     9481 tggatcactt caaagagcgg atccgttact cgaatctctt tattgacgat ttgtttttcg
     9541 atgaggcttg tcattttgct ccctcctttt atccttactt tataacggac ggcttatcat
     9601 gtctaatact tataaaacat acttaactat tccttttaac tatacttagt ggtatgcttt
     9661 tttaaaaaca ggagggaaaa aatggatatt cgtatactga cgtatttttt agcagtagct
     9721 agagaaaaaa atatcagccg agcagcaaaa tctctgcata tcacgcaacc tactctctca
     9781 aaacaactga aagatttaga agaagaactt ggtgtgacac ttttcactcg gggctcccga
     9841 gagatacagt tgacggattc tggtcgatat ctttattcaa aaggaaaaga aatcttgtcg
     9901 ttggtagaaa aaacggcgaa caatttaaca aatgacgcaa tcatctctgg agaaatctac
     9961 attggcggag gcgaaactaa agcaatctct ttcatttctg atagccttca ttcgttgatc
    10021 aaggcgcatc ctgatatcca gtttcattta tatagcggga atgcagatga tatcatagac
    10081 aaactggata gcggattact tgattttgga ctcgtaatcg aaccgacaaa caaacaaaaa
    10141 taccagtcat ttcgactgcc agcccaagat cgttggggac ttttgataca tcgaaatcat
    10201 cctttagcaa agcaaaccgt catccatccg caggaactga aaactgttcc tttgatcatt
    10261 tcccggcaaa cgtcagtgga cagtcaacta gctgaatggc taggtttcag catagatcag
    10321 ttatcgatcg tcggaacata taacttattg tacaatgctt ctttgatggt cgataacggg
    10381 acttttggtg cattagctct agatgggatc atcaatactt atgggacgga aaaaatattc
    10441 atcccactcg atccgccatt acaagcttca ctgaatctca tttggaaaaa agaccagcct
    10501 ctttctcctg ctgctcgtaa atttttagat gtcctaacgg agaaatacag ttaagtagag
    10561 tttttttcct tcgctttcag ctttttaaca acgaataaga taagcaaaag atccaacgat
    10621 taaataacat aagtttctta atttatttct tccttttatt tctgataatt ccagtaaatt
    10681 actataatta taaaaaaaga attgacaaaa cataactgtc tatataaaat tgattacgtt
    10741 aacaataatt cgtttcatgt gactagatca tactaggcat gaaaaatctc tgaggaacat
    10801 ggtttcccta ggaggttttt cgtgtctatt tttgtttggc cgcaatcaac tggtctagca
    10861 aacgtgaaaa ccaaatcttc aaaaagggtg cgcgcatgaa aatcaaaaag atctttaatc
    10921 aaaatgcagt attggtagat gacggtggac aggaaaaagt agctattgga aaagggattg
    10981 gatttgacag aaaaagaaat gatttgattt ttgatcgtga tgtcgaacgg atatttgtca
    11041 tggaaccaga aggtcaaatc aagttgcaaa atttacttaa tcagattgat gaacgctttt
    11101 tatttgcagc agaaacgatc attgatcatg cggaaactgt tttgatggaa aagttgaatg
    11161 aacatgtatt gatcgctttg accgaccaca ttgctttttc tgcggagaac attaataacg
    11221 gtatcgtcat ccgcaacaaa cttttaagag aaatcgaagt gctttacagt gatgaattca
    11281 gtattgctca atgggcagta gagtatctga caaaagagct tgggattcca tatacttatg
    11341 acgaagcagg atatatcgca atccatattc acagcggacg aagcggtcgg aacaataacc
    11401 atcgcagtat ccgtgaagtg acgattgtat ctgacatcat ccatttagtg gaatcagaat
    11461 tggaaacaga tatccattca gaaccatttt cactgaatta ttcaagactg gtgaatcatt
    11521 tacgactgct tctacaacga acccatgcgc aacaatatgc tgttttagac acggaaatcg
    11581 tagaaatggt caaacgaaaa tacccagaaa gctataagat ttctaaaaaa atccgtgtgt
    11641 tgctgaccaa agaataccag ctcgcgatca cgaaagaaga actgggttac ttggccatcc
    11701 atatcgagcg tttaagaagc gcaatcgtac aaacaaatgt taacaatcat gaggaggaaa
    11761 aaaattgaaa gcatatctac aacgaatggg acgttccctt caacttccag ttgcggtctt
    11821 acctgctgct gctttactag tagggatcgg aaactggtgg gcatcttata gtaacgacat
    11881 tgtcgctcat tttttacaag ctggcggtaa cgcagtttta ggtcaattac ctttgctgtt
    11941 tgccgttggg ttagcactag ggatgtcagt ggacaaatca ggtgctgctg ccttggcagg
    12001 tttggtcgca tttgaagttc cagtaaatgt tttaaaaact gattcagtag ctactttatt
    12061 gaatatcaaa ccagaatcag ttgatccatc ttttgctcag atcagtaacg tatttattgg
    12121 tattattgcc ggattgattg cggcagctct ttataatcgt ttccacgaag caaaattacc
    12181 gatggcttta tctttcttta gcggcaagcg tctagtgcca atcttggctg cctttgtcat
    12241 gttgctgatc agtgcagtgc tactgctcgt atggcctccg gtttactctg ctttagtttc
    12301 ttttgctaaa ttcattttga gtttaggctg gggtggtgca ggtctttatg gcttcttcaa
    12361 ccgtttactg atccctacag gattgcatca agcaatgaac tccgtgttct ggtttgacgt
    12421 agcaggaatc aatgatattg gtaaattttt ggcttctgaa ggaacaaaag gcgtaacagg
    12481 aatgtatcaa gctggatttt tcccaatcat gatgttcggg cttccagcag gagcatatgc
    12541 tatttacaga aatgcacgtc cagaaaacaa agcaaaaaca gcttccttga tgctagcagc
    12601 agcttttgct tcattcttta ctggtgtgac agaaccactt gaattttcat ttatgttcgt
    12661 tgcttggcca ttatatgtct tgcatgcaat tttcactggg atttctttag cagtgagtgc
    12721 attcttccat tggacagcag gatttgcctt tagtgccgga tttgtcgatt acttcctatc
    12781 tttgaaaaat ccgattgcga atcagccatt gatgttgatc gtccaaggat tagtaacagc
    12841 agtgatttac tactttggct ttaactttgc tatcaaaaaa ttccatctga tgactcctgg
    12901 ccgcgaggaa gcagatcttt cagatgacga tactgcaacg actaattcag acaataaata
    12961 tgcggcacaa gcaagcaaaa tctacgctgc attaggcgga gccgacaatg taacttcgat
    13021 cgataactgt actacacgcc ttcgtttgca agtcaaagat acaggcctga tcgatcaaaa
    13081 taaaatcaaa gccactggcg tacctggtat gaagatcatc gacggaaaaa atgcgcaagt
    13141 catcgtaggt acagaagtac aattcgttgc agatgagatg gcaaaactac atggtggtgc
    13201 tgcagcacga cctgcacaaa caaacaccgt ggttaaaaca gaaacatttg ccggtgaaac
    13261 gatcgaacaa gatatttacg ctatcgcaaa tgggaaactg attccaatca ctgaagtttc
    13321 agatgatgta ttcgcggaaa aaatgatggg tgacggctat gctgtattac cagaaaatgg
    13381 agaaatcttc tctccaatcg ctggtacgat cacaaacatt ttcccaacga aacatgctgt
    13441 cggaatccaa acagatgctg gtatcgaagt cttgcttcat atgggcatca acactgttga
    13501 cttaaaaggc gaaccattca ctttatatgt agaagaaggt caaaaagtcg caagaggtca
    13561 attgattgct ttagttgatc ttgccgctat tcaatctgca ggcaaaaaca cggatatggt
    13621 cgttgtattc acaaatggcg acaaagtcca aagcttagaa atcgaacccg cacgtgatgt
    13681 aaaagcaaat gataaaatcg gctctgtttc caacaaagcc tgagccatcg tcttccccag
    13741 acttttttat cgataaacaa acaggagctg agacaaaaat cttgtctcag ctcctttttc
    13801 cgaataaaaa cggcgttctc ctgccaactc cgcggtaata agtccagcta aacgaaacat
    13861 atgaagagct attttttatt tgactcttct tattacttga tgcagaacag ctttttcaca
    13921 aaatttttct tcatactcaa aactaatcgg ctttttcaca acctctttat acattattcc
    13981 tgatccaata tttcttttaa tgctgcttca agagaagtta atggttttcc caatactttt
    14041 tctaaatcat cagaggaaat agctaactga tcctttttaa tatcatgttg gatcgctaaa
    14101 aacatgtcag ctgcttcttg agggaatccg gcttctttta gattttcgac aaacgctgca
    14161 tcacttgctt caataatttc taactcttta cctgtcgcac gctctaatgc cttggctaat
    14221 tcttcatagt cagttagatt gccggataat tctaagattt ctggagagtc actttctact
    14281 agtacttttg ctgcagcttc tgcatattca cgtttcaatg cccaacctgt ttttccattt
    14341 cctgcagcat aaacgaattg accagttttt aaagcctgcc caatgatagg taattcattc
    14401 tctacatacc aattattccg taaaaatgta tgggaaatac ctgaatcctt aatcattttt
    14461 tcagtgaatt ggtgatctgg cgctaataca ctgatcgagt gatcggcatc tgcaaaactt
    14521 gtataagcga tataagatac cccagctgct tgtgctgcct tcactacatt cttatgttcg
    14581 gcttgacgat ttcctggaac gccagagaca aaaagcaatc gatctattcc tttcaacgct
    14641 tctttcattg agtctaaatc atcataatca ccaatacgta tattaaatcc agcttctttc
    14701 agtgcttctc ctttttcttc actacgtact agtacataga tttcattttg tggaaccatc
    14761 ttttttaaga attccagcgc ataaccacca aaacctccag ttgctcctgt tactaaataa
    14821 tgcatatttg ccactcccta ttctttttat ttgttaagat ttacagctgt acatttataa
    14881 attacacctt tatcataaag agtgtggtaa gataagtcaa gcaaaaaaaa tgaaaggatg
    14941 acaactgatg aagtattctc tgcaatttag tgatgcaatc catgtacttg cctatattga
    15001 aatgtttcaa gatacccgat cactttctag tgagatgatt gccagtagta tcgaaacaaa
    15061 tgcagcaaat gtacgtaaaa tcatgagtca gctcaaaaaa tccggtttga tctttacaaa
    15121 aaccggaaaa ccgcagcctt cccttgccaa aagtccagat cagatttctt tactagatgt
    15181 ctatcgcagc atcgaaggta atacacagct tatccaagtc gatccaaaaa caaatccaaa
    15241 ttgcgtcgtt ggtgcgaata tccaagaagc tttagaagaa agctacgctc ggctgcagaa
    15301 aaaggcagaa gaagaaatgg ctaagatcac acttgatagt ctgatacata aaatagccgt
    15361 tttggaaaaa gaaaaaagac cagaaaacac aggcctcgta gagagatttt tataattctc
    15421 tctactgtgc ctgcattttt ctgatcggaa tcgtctacat aaattctttt attctccggg
    15481 ggacaaaagc cttgtcatgc ccctttttcc tctctaatgc tcaggtcaaa gcgctgaagt
    15541 catgacgtct tgataaacgg tgttcaagta gctgaccctc ggcattagtt ctgaaaaatg
    15601 caaaatatgg aaagctattt cccatttttc ctctctaatg ctcaggtcaa agcgctactt
    15661 tcacgacctc tatattatca tggtttattg actaccggta tccagatttc tcccatatat
    15721 ttcccgttgg taactcccat ttcgactaca gcatttggac ccccaacata ggcgtaatct
    15781 tctacttctc ttaaaacatg cccaaaggcc gtattcgtca aatcatttct taattcttca
    15841 ggcgattctg ctaaagcgct tacaacaaga tacgttcctt ttgggaatgg gatgattcgc
    15901 gtagtgtttg gaacatcctg actcgtttga acaccgacat agtacatcat tttcccgtta
    15961 tagggttcgt tgactgtaaa gaaataatga ttttcagcag cttgtttcaa tgcatctatt
    16021 gttccattac cgataacttt ttgctcaaat gcttgtttct ctgcagccaa accgacaaaa
    16081 tccgtattgc tactcttcaa ttccacacca atacccgtca ccgtaaaatc tggtttttct
    16141 tcgatcctat actttgccat ttctcccacc ctttctatta tattaagttc atcttacata
    16201 aaattaaagg gaaatgacac gattacgctc ttttttctag ggatattttt attttttaac
    16261 tatttttttg ctttcactgc aatccaaatc tcactgtaaa cattactgaa atcctctccc
    16321 cattttgtaa aagagatctc gggagcttcg actaacccat aatctgaaga aggaagccat
    16381 tctgcataga ttttccccca agtatcttgt aaagtttggg gaaatggccc tttattagga
    16441 aaaatggccc aagtgtgttc ttctatagca agcatttcta aatcagcgta cggattttct
    16501 tttgtcgtag caaagccaat catgtgcatc aaactgccct tttcttccaa gcggtctcca
    16561 tcaaatccat aagaaacgtt gattacttga tttggatata aatctcctaa cttatgcatc
    16621 tcttcccttt gagtctccgt gatcgtctgc gctaactttt gtatttcttg attgactcct
    16681 tcaaatttga caggaacttt tttcgccaca cctgccacat aaaactgttc tttcttttcg
    16741 atacgaaatt ccatcgattt tcctcctctg acatcaataa aaaatgtcaa gcgtggaaaa
    16801 gatttttgta tgccgtatct actgatttct gaaggcagat atcctgacca atcacgaaaa
    16861 gctcttgaaa aaccttcgac tgtttcatat ccatatctaa acgccgtttc tgtcactctt
    16921 gatccatcta gaagatcgcg attagccaaa gccaatctac ggtttttgat atagtccatt
    16981 agcgacatcc ctgcaataaa cgtaaagatg cgttttaatt gatattcaga gattcctgta
    17041 ttttcggcta ttattttata ggaaagtcct tctgtcaaat gttcttcgat gtaatcgatc
    17101 aattggttca gatctttaag catatttatc ttcctccttg attgcctttt tatcatatta
    17161 tcaaagaaag tcaattactt gatgaatcag gaaccaattt agtcagatgt agaaaatgtt
    17221 gtatggatct aaagaaaatt ctcaagcagc gtttcgtaac ggataattgg tattatctgc
    17281 ctatctatgt tttaccttta gaaaaataaa ttttggggaa gacagattct aagtaaacaa
    17341 agcggtaaaa atatctttta ttcccttagt taatccgctt actacctact gtacaaagca
    17401 aattgttgtt caaactgctg atcagaacgc tgcttggatt tttctttgcg atacatcata
    17461 cctcttttat caattggaac aattatttat ttctaacaaa atcacttcat ttttgtcaga
    17521 taaataaaaa acaaaaaaag ttccatcttt aaaacacgct attcttttac tttttctcac
    17581 attctctaag aaaagaaaag gagaatgaat ttttgacaat tcgagcaaaa gtgattatca
    17641 aatatgtaaa atcagctact tttttcttaa acgtttcttt atactaaata taaataagtg
    17701 tttcatgaaa ggagaactag atgaataatt ggcttgagta ttttcctgaa aacgttttgg
    17761 aacgcggtta cagctatcat ctgcacggtt ttgtccgtca tttgaactat acaagcaagt
    17821 acttgtccgc aacagtttct ggcacggaag attataaggt agtgatcact tgggatgaaa
    17881 agaccaacat gacttgtgat tgtctatatg ccatagaagg aaaaaaatgc aaacacatgg
    17941 ctgctgtctt attcgcttac gaagaacgtc caataaaaaa atccaactac tcactttccg
    18001 aactctcgtc ccttgtttcc tccgctagtt cctctcttgt acgggagctt ttaacagaga
    18061 ttcttataga acatccgcac tttatcgaac gcttcaaagt taagatgcca tttcatgcaa
    18121 taaattattc agataaatta acaactatca tccataaata cgatcatatt atcaagaaaa
    18181 acaaaaacag gaaaacagcg aagttcatca tggagatgcg aaagttcatc caagaagcag
    18241 ttgaatcgct tattcagcaa aatgcctatc ttcccgcatt cgaattgatc aatgaagtga
    18301 ttgctactct cgaaacattc tattgggagc ctgaggatga acgaaccctt cttctgatag
    18361 aggactgtta ttatttatgg aaagaattat tagcagaagc acctcatgca gaaaaaaggc
    18421 aaatgttctc ttggttcgtc tgccaagtcg atcatactga cgcctcttat tcaaaacgct
    18481 actctataaa aatcctgaaa gaagactttc gggaaaaaga attttctaac caaaagaaaa
    18541 aaatagataa aaaactaaag aaacggtaaa gaaagacgat ttcaatgaaa aatagcaagt
    18601 aaacgataac aaccatccta aatccacaag aaatacagca gaccttgctt taaaaacacg
    18661 aatcatgcaa aggatgaagt aaagaagact taacgcgtac ccaatattag tcatttgact
    18721 attaggtacg cgttttgttt tataagtcat gacaaatttc cttcgttgct ggatagattt
    18781 tccggcattg ttgatagatt ttatgatact tttctacatt ttgtaagaga ggttccgctg
    18841 catctgtata ttggataaaa ttctgacaac aactttcagg tgtgtcgaac caccctaacc
    18901 ctagtgcagc aatcattgtt gcgcctaatg caggtccttc ctccatactt aaacaataga
    18961 ccgttgcatc gaaaatatca gcttggattt gtagccatgc aagatttttc gcgcctcctc
    19021 ccaccgaaac aatacgtgta aatctgcgac ccgctagttc tttacgtttc aatcccacca
    19081 ttgacaaatg ctcattaaaa atttagaata ttcacaagtt taacgacaat tatgaaaatt
    19141 tatgtcgtgc taaaggagtt ttgttattgg atgaaaagtt agatataaaa actgcgatca
    19201 aagacacgtt acctaccgtt ttcggttata tcggtattgg acttgcattt ggtatcgttg
    19261 ggaaagctgc cggatttcat ccactagtcg tcacgttgat gtccctgctg gtctatgctg
    19321 gttctgccca atttatcaca gtcagcatgc ttgctagtca cagcccattg ctttccatcg
    19381 ttttctcgac ctttctagtc aattcccgaa tgattctgat gagtatgacg attgctcctt
    19441 atttcaagaa aaatcggctg cttcaaaatc tgctgattgg cacattgctg acagatgaaa
    19501 gtttcgcact gggaatgaat aaattgaact atactggaca aaagttaaac tttcgttgga
    19561 tgaatacagc taattggatt tcttatttga cgtgggtggg ttcttctctt gttggcgcac
    19621 ttttagggaa ttttattact gatccgaaaa agtttggttt ggatttcgcc atcgtcgcta
    19681 tgtttatcgg gttactttat cttcaagtca tttctgatag aaacacctct aaacgattac
    19741 agttgatcct gattggtctc actttgattc tggtatatgt cggactgatt tttatcccaa
    19801 gcaacttagt gattgtagtt gtaacactga ttgggtgcgg attgggggtg tggatcaaac
    19861 atgccttctt ttgagtttac attgctgact attttaggtt gtactttagc aacttggctt
    19921 tctagggtcc taccatttgt cttactgaaa aaattcgatt taccgcaacc gttgcttgag
    19981 tatttaagtt ttgtcccgat cgtcattatg tctgctttat ggttcagcag tctatttacc
    20041 caaaatatcg gacatctgcc gcagatcaat ctcgaaaatg ctttggcttc agttcctaca
    20101 cttttagctg ctattctttc aaaaagctta ttggtgatcg tcttggcagg aattctttcc
    20161 ctttcgttga ttcgcttatt ataaataaaa aaacaagagc ttatggcaaa ttactgtcat
    20221 gcgctcttgt ttttatcaaa gtcaaataag aaaaaaatcg gcgtattctt gcttatccgt
    20281 tgaacggacc actaacaacg acttttccta acatatgtcc tgtttctacg tctttggttg
    20341 cttgtttcaa gttcttcgca ttcatcccat ctgaatagac cttgctcaat gtactgcgga
    20401 taatcccttc atttgctaaa gcagcaatgt gcgctaaagc ttctccttgc gtttcgattt
    20461 catagttata gtctgtttta gcgaacatat actcccagtc gaagctgata gattggtttt
    20521 tccaaacacc tatatctaac ggctctttga tccctacgat cgttcccaca tgtccaaatg
    20581 gtcggacaag gtgcttgatt tgatcaaagt agcgggtaat atcgaataat acagcgacat
    20641 actctacttg atcgattcct aattcacgaa aacttttact taagtcgtga tgataatcga
    20701 ttggatagtc tacacctgtt tttttcagcc attcaaaatt cttcggactt gcagtcgcgt
    20761 agacttctag gccagcccaa tgcgctagtt gattcaaaat cgaaccgacg cccccggatc
    20821 cgttgatcac taagattttt ttcccgcgat tggcattttc ttctggagtt agaccaaatt
    20881 tttcaaataa caattcataa gcggtcaatg aggtcaacgg caaggctgca gcttcttcat
    20941 ctgaaagatt ttttggtgca agagcgacaa tacgttcgtc aactagttgg tattcttgat
    21001 tgcttcctgc tcttgttgtt gtacctgcgt aaaaaacgcg atcgccgaca gaaaattttt
    21061 gcacttcgtc acctacagca acaactttcc cgactccatc aaaacctaag atacgtaaag
    21121 catttcttat cccgttatct tggcgaagtt tcgtatcgac aggattaaca gatactgcgt
    21181 tgacttttac cagaagatcc cgtgaactgg gtacaggtat ctgttctttt tcatcaataa
    21241 agctttttgg atcatcgatc ggcaaccctt cataaaaacc gactaccttc attaattcct
    21301 tttctgacat acgaattcct ccttagcttc atcaagttgg agcatccata cagtgttcat
    21361 ttcaatatat atagtatgct atttgttcca ccttttttat tcatcataat tattctctta
    21421 cttaaagtaa actatttgca cttttttggt taaaaaagag gttgcgacaa gacttttgtc
    21481 acaacctctt ataaacggtg ttctcctacc aactcttcgg tcacaagtca aaatattcat
    21541 caaacatgag aagctgtttt ttgaaattgc tccttgtgac tcagagttaa acggcaggct
    21601 cacaacctct gatataaacg gtgttcaatc aactgaccct cggtattagc tcaaaaaacg
    21661 acaaaatatg aagagctatt tttgtttggc tgttcttatt acttgataca ggacagcttt
    21721 ttcacgacct ctaattcacg gtgttcaagc aagaaatcat tgttcactga aaagcgttgg
    21781 atgttctttt tcaaaggtct ctaagatctc tcgtacttca tcagtagatt tcgtattcat
    21841 caactgaact cgcaagtcat ttgctcctgg aaatcctttg atatagattt taaagaaacg
    21901 atgtagtcct gtgatggaac gcgggatgat ttctgaataa tgatcttgca gatctagttg
    21961 cagacgaagt agtccgatca gttctttttc tgtatgttcc ctcgggtctt tttcaaatgc
    22021 ataaggattc ttgaaaatcc ctcggccaat catgatgcca tcaacgccat atttctcggc
    22081 caattcttct cctgtctggc gatcggggat atctccattg atcgtgatta gtgtttgtgg
    22141 agcgatttgg tcacgtaaag caatgatttt aggaatgact tcccaatgtg catctacttt
    22201 actcatctct ttacgcgtac gcaaatggac agaaagattg gctatatctt gatgaagtag
    22261 gtgactgatc cattcttcca tctcagacat ttccgtatag ccgatacgcg tcttgacgct
    22321 gacaggcaaa ccgccagctt tagctgcttc aatcaattgt gccgctactt ctggacgaag
    22381 gatcaagcca ctgccttttc cacgttctgc tacattaggg actgggcagc ccatgttgat
    22441 atcgattcct tggaagccca tttctgccat agcaatgctc atttctctaa aaaattctgg
    22501 cttgtctccc caaatatggg caaccatcgg ctgttcatct tctgtaaatg ttaatcttcc
    22561 tcgtacactg tcttttccat ctggatgaca gaaactgtct gagtttgtaa actcagtaaa
    22621 gaagacatcc ggtgctgctg catgctttac gacatggcga aatacaacat ctgttacatc
    22681 ttccattggt gctaaaacaa aaaaaggctt tggcagctct ttccaaaaat tagtagtcat
    22741 ttatttgtta ctctccattc tatcaagcag tgaagtcgca atctttctca aaaacattgt
    22801 cattatacta ggaaacaaaa aaagaagcaa agtgaacagc ttaaaagatg tttctgattg
    22861 agcaaaaaaa agactgtgac aaaaatctta tcacagtcca ttttccggaa taaatggtgt
    22921 tcaaaagctt gcatttgcgg taataagtcc aaccaaacga aaaataggag gagctatttt
    22981 tgtttggctg ttcttattac ttgatgcaga acagcttttt cacaacctct ccactaaacg
    23041 gtgttcaatc agctgaccct cggtattcgc tcaaaaaaca acaaaatatg aggaactatt
    23101 ttcccgtttg tttctctaat actcaggtca aaacgctgat ttcacaacct cttttctaac
    23161 ttctcaatcc tcttccttta ttgatcaaat accaagtaac ggcgtacaaa acaacgatga
    23221 ataacacaag tacgatcatc gatgttgcta ctggcacatc gatcgttcca aggaatccgt
    23281 aacggaaacc ggagatcata taaacgatcg gattgacttt tgaaacagct tgccaaaagg
    23341 gcggtaacat agagatggca tagaaaacgc cacctagata agttaacggc tgcaagacaa
    23401 atgtaggcac gatcgataca tcatcataag actgagcaaa aatcccgttg agcagtcctg
    23461 ctaatgaaaa caagattgcc gtcatcaata atgtaatgat gaccatgaac catgaataca
    23521 catgaagtgg tacaaagaac aaggaaatga tcgttacgag agagccgacg agaatactgc
    23581 gacccacacc accaatcaca aagccccaaa taatcacatg cgtaggaaca ggtgctacca
    23641 agatttcttc gatatttttc tgaaattttt gagagaagaa ggacgaagaa acattggcat
    23701 acgaactagt gatagcagac atcataatca aaccaggaac gatgaattcc atatatgaaa
    23761 aaccacccat gtcaccgatc cgcccaccga tcatttttcc gaaaataaca aaatacaagg
    23821 atgtcgtgat cactggcgga accagtgttt ggacccatat acgcaaatag cggttcgttt
    23881 ccttgatagc taaacttttt aatgcagtaa aataaagatt aaacattttt ctcctccgta
    23941 tgattatttt cttctgtgat tttcaagaac agttcttcta aacgattcga cttattcctc
    24001 atagaaagaa ctttgattcc ttgtcttgta agctgatcga agattccgtt caccccttga
    24061 tttcgttcaa cttcgacagc gattgtctgc tcatcttcaa atgtacaagc atatccttca
    24121 atcacaggtt tggtatcata tggcgctaaa tcaaagataa atgtttcaaa ttgcagtttt
    24181 gacagaagct ctttcatact tgtattctcg atcagttcac ccgattggat gattccgatg
    24241 ttgcgacaaa gcatttcagc ttcttctaga taatgcgtcg tcaaaatgat cgttgtacca
    24301 ttttcgttca attctcgtag aaactcccac atctcgcgtc tcaactcgat gtcaactcct
    24361 gctgttggtt catccaagat cagcaaacgt ggttcatgca tcaatgccct agcaatcatc
    24421 agtcttcgct tcattccccc ggaaagcata cgtgcacgga catttctctt ttcccaaaga
    24481 ttggactgct tcaaatattt ttcgctgcgt ttcatcgctt ctttgcgaga gacaccgtag
    24541 tagcctgctt gattcacgac gatttgctgg accgtttcaa aagggttaaa attgaactct
    24601 tgtggaacca atccaatctg ttgctttgct cgaactagat ccttgtccag atcataaccg
    24661 aagacattca cttttccaga tgttttattg actaaagaag taataatccc gatcgttgta
    24721 gacttcccag ctccatttgg ccctaatagc gcatagaaat ctccttcttt caccgaaaga
    24781 tcgattcccc gcaatgcttc gaccccactt ccatagatct ttttcaaatt atttatttca
    24841 agcgcatttg ccatttattt cctatctcct tatagacatg attcttaatt gtatcatgga
    24901 atacagcaga tgaaaaaaca acttggcttc cacacaaaaa cacacctgct aacaaagagg
    24961 agatgtgttt tctagttcat gatcatcttc gatagaataa ctatctaaac aactctggaa
    25021 cttttaaaat cataaaagta ccgacagcaa ctactacgat gacatataga agatccttat
    25081 aactgaggtt cttgtctttt ttattcatgt taagctttcc tccgtccttt tatcgaaagc
    25141 ttttttcttt tattttaacc gaaataaata aaatggaaat agttattttc aatttctgtt
    25201 ttcgctgttt gttttacgga gaactttgcc atggaacgtg cgtctcgtcg ctgatgctaa
    25261 gttttttcga taaaagctgc tagaaggaag acagcgtggt ttattttgta tcgtcttttg
    25321 ctaaatcttc caagatcatc tggacagcag actcgttccc attgaattct gccacttttt
    25381 tggcatcaat gtacttcttt tgataatcgt ctttttggac ccacgcatca tgcttcgttt
    25441 gataaagtta atcaaacgga taccactgac gctgttcatc gaacaacaaa ctttcttttt
    25501 gggcctgttc aactatggat ttaggataat tcaaaacttt cagcaaggca atcgcatttc
    25561 gggtccttga aggtccttct tttaatttga aatcaaaact gattcctttt ccttctgtta
    25621 cttgttcttc aaagtggaca ttctcacaat aattctttaa aatctctgtc aattcgatat
    25681 catgtgtggc gacaaatgct aaagatggat actccgcaag ccaccgaacg actgaagcgg
    25741 aagaagcaat ccgttcgatc gtatttgttc cttttaaaat ctcatctacg aagcagtagc
    25801 agcgttcttt ggaagccact tggtccagca aacgtttgat cgatttgatt tctgaaacaa
    25861 aataactgtc gccttcaaat aaatcatctt cgattgccat ggaagtcaac acatgtccag
    25921 gttgcagggt aaactgttct gcaatcgctg tttggatcgt ctgtgctaga atacagctga
    25981 tggctatact tttgacatac gtagattttc ctgatgcatt ggaacccgtg actaatgtat
    26041 tcttctgcca gttgactgga ttaactaccg cttcttttaa caatggatga tagatatctt
    26101 tcgctgtcac accgccctca gtaaactctg gtcggcaagt gatcggcata taggtgcgat
    26161 aattcaaaac ggctgctgca acttccaatt ctcccagcaa ttcccacagc ttgatggctt
    26221 cagttgaatg cttttctaat ttagtgagaa cgaaatgata ggagataaat ggcagcatga
    26281 acatgatgtt gacatattca aaaatcaatt ctgcttcact cccgctcttc attcgaaatg
    26341 aaaaacctaa tttagggatg tctcttaatg gtttagtttg ctgtttcagc tctttttgaa
    26401 gtggtgtcgt catttttgct aactgattgg cggctgaaat cgttgaaacc aaataactca
    26461 tgctattcag ctctgtttct agtgtttgtt tcttcactag ataatagacc gtattgaata
    26521 ctaagccacc gattgctaga tagattccta gtacttgccc taaaagaagc aaacctacac
    26581 ccaccagcgg aagcaagcca agaaaaataa ataaacctac gcgtccaatc tttttacttt
    26641 ttccatccgc tagatattgt tttgcaaaat tatgatcttt ttttcctaaa cgagcgaatt
    26701 gatattggat tctttctctc agttgaggat tttcctgata aaaagcaatt agtttttcta
    26761 actgataatc ttctccaaaa tcaaagctac gtaaacgctg atacaacgct tctgaaccta
    26821 cactagaata ggtactgttg atcccttcaa atacttcgaa catatccaag tcataccaag
    26881 taagatcgtc gatttcacta tcccatgaac ggaatttttt ctccgtgagc cacgcatcct
    26941 tcaaactttc ttctttatca aatctcggtt gataaggaat ttttccccaa ttactacgaa
    27001 ctgtttcctt tactttcaaa cgtgaaaaaa tgtctaaaac aactaataaa ataacaactg
    27061 caataataat taaaacgata aattctcttt ggcccatatc cctctccgtt ccttgatttg
    27121 ttagttttag tatagcactg ttgcgctatt tgaaaagggg gtacaaaaat aactgtcttc
    27181 gttacctaat tcgtatcaat cacaccaaaa taaaaacacc ttccaaaaaa gaagatgtct
    27241 ttaaaacgag atacaatttt ttgtcattca cttcaggtaa attagagcca attaaaccct
    27301 ccgcaacttg acggagatgg agaagatgcc cccgtctaat ctagcggtca tctctcctcc
    27361 cattccttcc accaattttt ttgacaggta aagcccgatt ccgctagatt ccgtatttgt
    27421 gcggctggta ttttcggtat aaaaacgctg gaagactttt tcaacagagg tttgcgctcc
    27481 tggtttgata ggattggcca ctgttaatcg aatgaatgaa tcctcttttg aaaatgtcac
    27541 ctttgcttgt ccatctgcat aacgcaataa attctgtatg atattttgca gcactcgcag
    27601 caacatgagc ggatctgcta atacagttgt atttatcgag tgttcagcga acgctacctc
    27661 gatatttttc tcagaaaatt gttcataaaa agagaaaaat acttcttcca cctctttaga
    27721 aaaagaaagc gtatggagat ccatttcttt ttgcttcgtc tctattcgag caagatcata
    27781 aaactgatcc gtcatactga gtaatcttgc aacagattgt ttgatgatcg ttaaatactt
    27841 ctcccgtttc tccgtatcct ctacctgttc cagtaattgt acataaccgt taatagcagt
    27901 caaaggagtt ctgagatcat gagaaaggcc gacgatcgat agtctgatgt tttcttccat
    27961 ttcttgaaat gcttgtcctt tttgttcatt ttcatccacc catgtattca gtgcatctac
    28021 taggtccatt agattctttt ctcgaaattc gactgaaaga cgaccaccat attcttgtcg
    28081 ttcagaaaga gtggcgattt tcttagttaa tctcttgatt tccctttgca ggaagaaaat
    28141 aaaacttccc ataaagataa caacgagaag caacagccac ttaatcaaat ctaaacccca
    28201 ctccccacac cgtatgaata tacacagcat gtgcctttgc tagtttccct cgaagattgg
    28261 aaatatgcat attcactgtt ttctcactat caaaatatgg ttcttgccaa actgtttcat
    28321 aaagatttgc tcgcgaaaat acttttttcg gatgttctaa aaaaagcttc agcagatcga
    28381 attctcttcc tgtcaaatgg acagccacac cattcacatt tacatccctc gactctttgt
    28441 ccagtaagat ttccttgtaa tagatgcgtt gcgacagatc ttttacttgg acagaagtct
    28501 gatgacgaag ttggatgccg attcgtaaca acagttcttc gatatcaaat ggtttcgtca
    28561 catagtcatc cgctcctgct gccaacaagg aaactttatc tctttgatcg ctttttgctg
    28621 aaagaacgat gatcggaaca ttcgatgtct gtcggatttc tgctaacaat gcttcacctg
    28681 aaagccctgg aagcatgaga tctagaagga tcaaatcgac aggatatgtg cttaacaata
    28741 attttccttc cgtacctgaa taagcatcaa gaagtttgta tctctgttca agaacctcct
    28801 ccagtaaaga atgaacagct tcatcgtctt cgataatcaa aatagtttcc agcaggaaca
    28861 cctacttaat gtcagatttt tggaaaataa acattcctag agctgatgat accacgattg
    28921 ttactagact gaccagaatc attttcggtg cttgcgaata agttgcttgt tgcgcaaagt
    28981 ccgtatacat gagccacgtt tccgtaaacc actccgttag aaattccaag cctttgattt
    29041 ttgcgaaaac accgggaacg aaggccgttc ccatgatata aagaaaagaa agaagcaaac
    29101 tgacactggt acttctagtg atgaatgtca aagccactgg aacagataat gtcgctaata
    29161 tcagcagaag caatacagga aatactttta gaacataatt tccatagttt ttgattccct
    29221 caacttcacc aaatccgaaa gcaagtgtgt aagcaatcat ggctagcccc gtaatcaaaa
    29281 ccacgccaag tgttgtgatc aaaagcgtaa cgagaagttt cgacacataa taagtcattc
    29341 gattccgtcc taaagataac gtattgcgaa tcgtaccgtt ttgaaattct tccccaatat
    29401 aaaagcacgc aaatgctgcg aaagccagaa gaatccatgc agccattttt tccaccatta
    29461 aaatccctgt tgcaccgttg atgactgtat ccgttgcttg gtttaattca ttgccgtatt
    29521 ttgtatgcat ataccattcg ttccaagaat aaaaaagcgg aagtacgacc atcagtccta
    29581 gtgagaccca cattttacgg ctcttccata cttttatttt ttcagcagtt aatagattaa
    29641 acatgtggat tgcctccagt taattgtaag aaataatctt ccagtttttg cccaactagg
    29701 tggataccat ccacaggaac ttttgcctct accaatgctt gattgatggc tgctacttgg
    29761 tcaattcctt caaaaagctg gataacacgg ctagattgga caaaataatc cctataacca
    29821 agagagtcga gaaccgttac tgcttgttcc gtcgccgaag tgtcaatttt tataaattga
    29881 cgagattctt gtgccaattc ttctttcgat aattctttga tcaagtgtcc ttcatgcaaa
    29941 ataccgtagt gagtggcgat ctgtgacaat tcatctagca agtggctaga aagcaagacg
    30001 gtgatgcccc gttcttttac caaacgttgg atgatttctc gcatttctgc catccctgct
    30061 ggatccatcc cattcgtcgg ttcatccaaa atcaaaaatt ctggattcgt gatcagtgca
    30121 tttgcaatag ctaaacgctg gcgcatacct aaagagaaat tctttgcttt ctttttccct
    30181 gtattttcca atcgcatcat tttcagcagg tcttcgattt ctctatccga cacaccgccg
    30241 ttcgctgctt ggatacgtag gttatctctt gcagttaatt ctggataaag agcaggggtt
    30301 tcaatcgatt gacccatacg tcgtcttgct gcctgcaaat ccgtcgttcc aaataattcg
    30361 atcgaacctt catcaatcga gatcaaaccc ataatagttc tcataaaggt agacttaccc
    30421 gctccattct ccccaatcaa accatagatc attccacgtt tgatttcgat cgatacttta
    30481 tctaatgctt tggcagcacc gtattttttg gttataccag ttgctttcaa gaccgtttca
    30541 tttccaaaat ccatacttat ccttctttct tattgataag tgaagtatag ttgacgggta
    30601 taaagaaagc agccagaaat gtataaagaa agtgtaaatt ttccaattga atttcaagaa
    30661 aaatcagact gtctcgcaga cgtggttgag ttgtctgcca atcaaagagc gcaccaaaca
    30721 gtgctaatcc aagtggactg gccaccatgg taatcgttgt tatcgttgac atcagacgtc
    30781 cttgtatatg cgttggaact tctcgctgaa gccagaccat ataaaaagca aaagaaaaca
    30841 ttaatcctta aaaacggact tatgaaaaat aatacatgcc gtttgggatt tacaattagc
    30901 taccaaataa gaggttatga caaaagactt ttcacaatcc cttcttccga ataaacggtg
    30961 ttctcctgcc aactcctcgg tcacaagtca caatatttat caaacatgag aagcaatttt
    31021 tgtaaattcc ttcttatttc ttgaagctga ccacttctgt cacaacctca gaagcggata
    31081 aataatattg tttgatgata ctttatcttt ttcccgtttg tttatagatc gaatgatatt
    31141 atagaccaag aatcctacct attaacatag ctaaaaacac aaaaaaggca ctttccaaat
    31201 tgtggaaagt gccagaaaag ttaggattaa ggtaactgcg ctcagcattg cttcgcccag
    31261 tacgattctc gtaactcgtg aactcgaacg ataatcgcaa ttaacgtttt gagaactgtg
    31321 aagctttacg ggctttctta agacctggtt aaacaaactt ttgttttata atgttttaca
    31381 gagaaagaaa tcgtgtaaaa tcagcattta atgattcata taattctact tagttaaata
    31441 aagttatatc ctgtcattac ctcaaatcat taccacaact tggcgagttg gctgattgaa
    31501 gaatattctg tgccaaataa aaaaaatgat gccaaaaata agtacactac tcaatactta
    31561 ttttcaacat cattaatcct aaaatagctt cgcttttacc cgttactatc taccctttcg
    31621 gaaggggtat ttcatctgac taaagaatag catccaagat accaatagtc aagtaattaa
    31681 tttaccatac tccattacaa ttttttcaaa aaagtggaaa acttctacaa gttcatgatt
    31741 cttttcgtac attttaccat taacttttat gcgatcaagt aaatcagata gagcctcaaa
    31801 gtttgttgtt ttcaactttt gtgtttgaac atatttttcg tgaagatata tagtagccac
    31861 aatatcattc attttcatat tggtgagtgc tctggcgatt agttcagaat caagacccgc
    31921 attggttgca aactgtgtta attgaataac aggccttctt ttcttcaagt tgctgtcagc
    31981 tctaccaaat tgataaggtt caacaatatt ataaataaga ggtctactat gtgcagaggc
    32041 atttctgaca ttcgtaacat attttaataa tttttgagct gtttttaatc ctagatatcc
    32101 aaaatgttct tcttcaaaat agaaggtgat aaatctctct aaatttccta gggtcataac
    32161 ttctaataaa gcccaaattg aaatcttatc atgatgatga ttataaaaat caaaatcata
    32221 tccgaacttc cctttcactt tatctagaat cttttcagaa gcttgtgtat attcagacaa
    32281 gatttcttcg tttgttttag tattaccttt ttttctttga ctatcaataa atttattttg
    32341 catatacata tcgtaatctt caacaatttt atatccatct tcggttaatg aattagtgat
    32401 tgaacttatt atcaaagttt tcaaagaatg ttcaagttca aaaatcattc tactcaaaat
    32461 cattcttaaa tacatatcaa tctttgctaa atcagctaat tttacaaatg ataaatctat
    32521 atactttcca tttatatctt tttcaaaatt cttacggtat gcggttacct taaaataata
    32581 cgttcgatat aataaaatat cctgaacaat actttcatcc gattcagaaa tttctattcc
    32641 tttaaatcta gcatatttaa tttgatccgt aattgaaaaa atttccttgt ttttagcttt
    32701 tttacaaaga tctttaattt cttctgataa ttcttcagag acttgattaa ctctctcttc
    32761 ttcttctaac tgcaacttta atttagccaa tttgtcgctt ttaataaaaa cacacctcct
    32821 ttatctcttt atttttatac tatcttccca acatctccat aaacttccgc aattcttctt
    32881 gcgcttcatc tgttgtcccg tgcaattcac ctagcatttc aaataattta tctgtcgatt
    32941 tttctatctc ttgcttcaca tctgctaatt cttgtgcaag gtgtggtaat ggagtcactt
    33001 cttcttcctc aaacgtgtct acatatcttg gaatgtttag gttataatca ttctctttaa
    33061 tttcgtctaa agttgctaca tgtgcatatt tttcaacatc ttcacgtttt tcataggttt
    33121 caataatttt gtcaatgttt tctggtgata atttattctg atttttccct ttgacaaatt
    33181 cactagaagc atcaataaat agaatatctt ttgttctcct agattctctt cctttgaata
    33241 ccaacacagc agttggaata cttgtcccat aaaatagatt tgccggcaat ccgataacag
    33301 tgtctaacaa gttattatca atgatatttt tccggattct cccttcagaa gctcctcgga
    33361 atagtacacc atgaggcaat acaatcgcca tcgttccagt tttatctaag tgatacaggc
    33421 catgtagcac aaacgcatag tctgctttag aagcgggtgc tacgccataa cctttaaacc
    33481 gtgtgtcttt ttctcgatcc acattcttta tatcccactt agcagaatat ggcggattag
    33541 ccactacagc atcaaatttt aatggaattt gcataccatc tttttctgcg aatggccagt
    33601 ctgcatcaag ggtatcacca cgtttcaaat tcatatttcg ataattaata ccatgcatca
    33661 tcagattcat acgagctaag ttataggttg tcgtattcaa ctcttgccca tagaaatcaa
    33721 cactgccttg cttattgcca tcgggtagtt catttttcac tgtcagcagc aacgagcctg
    33781 atcccattgc tggatcataa actcgaaatt gagtatcatc cgctttcgca tctttggtta
    33841 caatctttgc tagtacttgg cttacttcat gtggggtata aaattctcca ccttttttcc
    33901 ctgcattggc agcaaattga ccaattaagt attcatacac atcacccagg atatcgtgac
    33961 cagaatcatc tttaaaggta aaatcgttca ccatcaaaac aacatcattc aaggcttttg
    34021 ctcgttcatt cgtatttgat cctaaccgag tatctccaag attaatgtcc gaaaaaacat
    34081 tggcaaaatc atcttcggca actggattcc gtttcgcatt caaattgaac gaatcaagca
    34141 tatcctgaaa gtcactcgct ttgatttggt ggttttcaat ctttgatact aactgttccc
    34201 aagtatattc cggagcaatc gcataaccga ttcctcgact gatttcttcc aagtaatctt
    34261 ctttttcttc agagtcagtg acttcgtagt actcgtctaa cccatttttt tctaaatact
    34321 cgtcttgatt ttctgataag tagcggtaga acataaatgg taaaatataa tttttatact
    34381 cacttgcatc cattgttcca cgtaatttat tggccattgc ccataatttt gctgtaatct
    34441 cacttgcatt actcattaat tttctctcct tttagacaaa cattttttgt agcaatgttt
    34501 ttttcatttc ttttagtgaa tccaactcac gctgatgaag ggtgatggtg gtgtcgagac
    34561 ttttaaagaa gtccgcaatt ttttcttgct cgttattatt ttttggaatc atgagttcag
    34621 tttcaaaaaa atcagatgca gcaatattta aaagcccatg attcctagct ccctcagcag
    34681 catgcttaga aacctcttta taccaacgat ctgtatcata atatgacgct aaaaaatctg
    34741 aatttatgtc gaccggtcta aaacaaatat acaatgttga taatacaccc atgtcatact
    34801 tatctagtcg cttaacagca ccccaaggat agccattgga gtagctttta ttataggcaa
    34861 actcaccttt cttcagcaga taatatccgc taacatcctt actggcaatt tgcttattaa
    34921 aaaaagtatt ctgatcaact aatccaaatt gtgctgatat agtcagtgga agtgttgatt
    34981 caagcttttt gttctttctg gtcaccctag tggcaacttc ccccaactta cgctgttccc
    35041 aagcgtcagt aaatccagca aaacgaattt ctggtttatc ttcacctgtt ttaggaaaca
    35101 ttttttttaa ataagtttgt tttgtttgct ctaacagatc aagctcacgc tgatgaaggg
    35161 tgatggtcgt gtcaaggctc tcaaaaaagg tagaaatttg cttttgttct tcaatactag
    35221 gaaccattac tttaactgat tttagcgttg gaaatttcaa attccatgta tcagatgtta
    35281 agccttgtga gtttctcttg aacgtttgaa tcatgtcata tcgcttgaaa tcatacgcaa
    35341 agaacttcga gtcaatatct ttttttggaa tgataactgt gtatgcaggg cttagaatgc
    35401 cattataagg ggaatatccg cttgcacctt gccacattct cattgagttg tatgcaatat
    35461 caccaacttc aactttcttg taatttgact tgtcatcact ggaattatct tttctatcaa
    35521 gttcgcttgc ctttacaact cctgaattaa tagtgaccga gataagctct ccttcgccac
    35581 tacgttctga ccgttcagag aacacctccc caaccttacg ctcttcccaa tctccctcgt
    35641 atccgtcaaa tcgaatttca ggttcttttg ttatttcatt gctcatttta actctccttc
    35701 gatcttcgtt atctccttat caaaatcaga aacgatatgc tgatgtttat tgaactcctt
    35761 gtactcatca accgcttttc tcttagctgc tttactgcta atttttccgt ttccatcaag
    35821 aatttgatag cgattaaatg ttagaaattc atctatgctt ttggcaaaat cttccatacc
    35881 taaaagtgtt tcatcttcca ataatcgctc aacataatca aaataagaag atacgttccg
    35941 ttcaagactg cgaatttgtt tttctgataa ataattttta gcaactgata catctgactg
    36001 taggattctt ccatctggag agtttttcca agtcgtcagt cccatgttct cttttgtttt
    36061 atctgcacca ttaaaaacaa tctccgcagc tgtttttcca gtaatagcat agtgaaattt
    36121 attttgtaca gtggcataaa actgcttcgt aatttcagag tttttgtcat aatcataaga
    36181 gatttctgca aatacatcag taatttgttg ccaaattctt cgttcactgg cacgaattga
    36241 gcgaaccgtt tctaataact ctcggaagta atcctttcca aaagcattct caccttgttt
    36301 cattcgctct acgtcaattt tgaagccctt ttgaatatag tctttcagaa tatctgttgc
    36361 ccagattcga aattttgttg ctttttgaga attaactcgg taaccaatag aaataatcgc
    36421 atcgagatta taatatttga ccttatttgt ttgtgttttt ccatctattg cgccatgttg
    36481 agtggtattt tccaaaatgg aaacaaccac ttcttcatct aattcaccag actcaaatat
    36541 attttttaaa tgcttgctaa ttgctggtac cccaacatca aaaagttgtg aaatcgtctt
    36601 ttgcgtcgcc caaattgtct cttctcgaat aagcacttcg actttatcac tatcttcata
    36661 aattaaaaac tgaatttcat tcaatagaac ttactcccct ttcttagtct cgtccgccat
    36721 ctgatagaaa gctttccgaa attcaattcg atacttaacc catgaaagat tcgccacttc
    36781 cgctgctgcg atttctttat aatctgttcg tgcatcgttc atcattgctg ttagttcacc
    36841 ttgtttgtcc atatcttctt gaccaactcg atgccgtgaa attaatttgg ctaaatcttt
    36901 tggcttcaca ctattatcca atccccatgt gcgaacaaat tctgtatata gtttgatatt
    36961 gctatctttt tgagattgtt ccatcgcttg attcatttct tcaacatctc taggagccgg
    37021 atacttatca aagatgaatt ccttcgtaaa gatcttggaa acaaaattgc gaactttcgt
    37081 aatctcctta tcgctatccg attttgcaat ttcaacatcg atctcatttt ttgtcagctc
    37141 agcttgatcc attttatctt catgaacctc atctgccatt cgtgcgatca attcaatcag
    37201 ataatcataa ttgatcgtca catcgtgaat atgcgtcatc tctaaattga cttgcgatat
    37261 atcgatattt tcgatttggg ctcggcgttc acgcaactcg ttagcaagta ccgttgtcag
    37321 catgacctct tgatcctctg taattcctaa gcggtcatag aacagttccg gttcatcata
    37381 aacagaaaca ggattttttt catcgtcctc cgtgaattgc ttcagttgat ttagtaatcg
    37441 attgtactcc tgtaatcctt caaatacttc ctcttgcgct ttttcacttg gaggtaattg
    37501 aataaaatta tctgttagtt cagctaattt ctgaatcact tctttggttt ctgattcgat
    37561 tttactaaat gatttcgata aaattcccga ctcttcattg tcttttttta attcatctag
    37621 cgatagttgc tctgctgctg aatctcgatt tgaataaata gcaaaagact tattcatttc
    37681 gtattcattt tggatgggcc aacgataatt aacaatattt ccttgtggct ttgcatccct
    37741 atcatggatt ctattcgtac gtgaatatgc ttgaattaga ttgccacctt ttaacgtacg
    37801 atcaatgtac aatgtattaa gctccggtgc atcaaaacct gttaatagtt gatccacgac
    37861 aatgactaga tccaaataat ttccatcgtc agctgttttg ttcaaacgtc tagctaaatc
    37921 ttctgtatat gatttaactg tcgtcatatc aaaagcagta ccaaacaatc tattataaga
    37981 ttgaattgct cggtgaagat tttcatttgt ttttagctga tgactactat ttgatgtatc
    38041 catcgaaaaa ctaatggcaa cttttatctg atcctcaatt gaccgtttat tattttcttc
    38101 cataaattta tcaaaatatt ccattgctcg aggagtacta gcacgatttc cccctacatg
    38161 tactgtaaat aacgcattgt atttccgatt attagagcgt tctttccagt tatcaaaaat
    38221 atcttcaaca acgagttcta catgctcggg actatgatca tacacactgc cacgaagatt
    38281 gtcgtcaata tcttcttctg taggatctgc tggtgcttca atcgtctcct taaactccac
    38341 tttgaatccc aaaacgtttt tatcagcgat agcttcttta atcgtataag catgtaataa
    38401 gtcaccaaaa atttctcgcg tttctggaaa cttaggtgta cctgtataac caacccaagc
    38461 agagttaggc aaggcttttc gaatagattc tagcatccct tcatttttag tcccatcacc
    38521 tgttgaacga tgtgcttcat caacaataaa taatacattc tcagttaatg gttgaaagct
    38581 gtctcttgtt acatatcgag acattttttg aatacttgtt actatgatgt ttttatcact
    38641 ttttttggta agtttacggt gcaagtcaga aatattggca gtatcactta caacaccagt
    38701 tttcccttca aatccagcga ttggatcata tgctctatag gcatctgctg tctggtttgt
    38761 caatgcaatt cggtctacca agaaaataac cttgtctaca tttgataagc gactcgctaa
    38821 ccatgccgtt ttaaaacttg taatcgtttt tcctgaacct gtcgtatgcc aaatatagcc
    38881 tagcttgccc tcgtcatgct taaaatcaaa tttcctaact ttatcaagta cccgttttgt
    38941 tgcatagact tgatacggac gcatgacttt gatactttct ttgttctttg taccatccaa
    39001 caccatatat cgagtagata aatcatgggc catgggaata gacaatactt tatctgcaaa
    39061 cagtttccat gaacgtactg gatgagctgt ttcttcatct tgccaattga aagcaaatgc
    39121 acgattgaaa ttttgtaatg tagtatttgc catgtaacga atatcaaacg gggtcatcgc
    39181 aatgagtatc tgtaaggtag aaaaaatccc actaaattgt ttctcagcaa tatattgttc
    39241 catttgattt aaagcttctg tcgcattatg tagcgccttt ttcaactcaa tttgaataat
    39301 cggtaaccca ttaatcaaaa gcgtaatatc aaaccgacga ttgggcttac catcaacaac
    39361 ttttggacgt tgaatttgat taacgacttg atagactgta tttccgccgc caacttgggc
    39421 ttgatcaaaa acggtcaaaa aaacatgctt tccgttatca agatcaactt caatttctga
    39481 tacaccattt acaccatata aaaattgtcc agcttgataa ggcgtattaa tattggtaat
    39541 aatttttttc acttgattga actctgttgc agataacggt tcatctagcc gagcttgatt
    39601 attttgttct agaatttttt tgaagttgtt ccataattgt tctgttgttt taatttcagc
    39661 tttatattcc cattgtttta cgccaccgat tcttgttaga taatccacaa cttcttgctc
    39721 gaaccttaat tcagattgac tttttatacc gaattgcttt gtcataatct attcctccaa
    39781 acttttttct aacatagaat ttgtaaattg ctctaacaag cgagtatata tacttaactt
    39841 actttgtaat ttcaatgatt cagtgtaaat cccccctatt tttctttgtt cttctataag
    39901 aggtagcgga ataacaagtt gttccagaga ctgttttgtt aaccttaaaa ctggacctgt
    39961 tccttgaaga cctcgatctt tttgacgttg aatatcttta tgattgttaa ataagtaaag
    40021 aaaatagcgc ttgtctagca aatcactttt aaactctact tttgtaaaat ttagagacag
    40081 aactttacca acattctgtc cacttaccat tgttgcccgt tgaagtgaat tactaataac
    40141 aacatcgcgt ttatctaaag atacttcttg atcaaataaa tagtttactc tttcctcttg
    40201 agtcgcttca ttataatact tatgatcttc ttcaaatgaa gcttgatcgt aataatcaat
    40261 ttcttgattg ccaaactgtt tttcagctct tgattgatta attccttgaa caaaggttac
    40321 aaactcagaa agctttctca tttccatata tacttcctcc taaaatacaa ttcaggtctc
    40381 atttaaacga tttatcgaaa taatcatata tttctttttc gtttctgcgt ttttataata
    40441 aaccttatac agtaattcgt caatggaaat aattttatat tacaaaaaat ccgcaaaaaa
    40501 tgcggattcc tttaaatatt taatctttat tctagtgtag tacaagccta taccctaacg
    40561 ttacatatct cattcattat tataccagta tttcttcatg acacataagg gtgtaacata
    40621 ataattttaa acgaaatgac tacaagtagt cattgaagta agtcttcata agatacctgt
    40681 aggatatccc taattgctct caattgatct aacttaatgt gttgccggcc accttcaatt
    40741 ttaaccaatg tttccctagt tatagcaatt ttatgaagct gtaggtctct aatcagctcg
    40801 gtttgaccaa ttcctttttc taatcggatt cgtctaatat tgctaccgat tacattttct
    40861 ttatcaataa ttttttcctc tttcaagaat agcacacctt ttggactaaa attagtcctt
    40921 tttcttatta atcttaaaga ttcggtatgc tacaatggga ctagtattag tccacattca
    40981 attttaagga ggaatttttt tgaagaaatt tgcaatcatt ctaacctgcg ctttactcat
    41041 cggaactata agcgggtgta ccacttctga aacaagttct acaagtacgg aaactagtac
    41101 aacaacctca gaaaagaatt acccaataca tttttttccg gttccagatg gatttgaagc
    41161 ttattatcat gataaaaaac tagatgtccc tttatcagaa actgaatcta ctgaaaagat
    41221 tttgccaatt gaaattgaaa gaaatcaaga cgatataaaa ctaaaagctg atcttccctt
    41281 actgaacagc acacaaattg atagacatga aaatattaaa gttaatattg aaaaaggagc
    41341 gttagcaaaa ctttatactg aaaaagttga acaatttttt aagtctggtg ccaataaaga
    41401 cttttcaaaa ataagcgatt attcggagaa cttttttaat gaaacccaag atgaaatcat
    41461 gaactcaact tttatggctg aagatatgta caatatgaca ttaaaaaaaa taaaagctta
    41521 cgaccatccg ttaaatctga cactaaataa tggactgctt tcttttgtat tagcaggtta
    41581 cgttgactat gaatattcac cagattattt ggagaaacct cttcaacacg agaacaatga
    41641 tattaatttt agatttgtct acgagtcaaa aagtaaaaca tggttagttg atcaattaag
    41701 cacgataaac acaagcttcc atgaattacc taaacctgaa aatgaagttg agatggtcat
    41761 taaaatcttc taaaaaagaa gcgttgaagg agaaatattc ctttcaacgc tcttttttat
    41821 atgcttagaa acataaataa attgtatact ttctttttag cccctattac ttttcacgaa
    41881 aaatatcttt ttttcgacgc tagcgtttct ctacttctaa tactgtacac agtttttgta
    41941 ttattgaaaa attactcatt atttagcatt aatccacatc gttttatcaa tcgaccttca
    42001 tactaaacta ctttaaagtc atcttccttc tcgtttttca ttaaatcaga tacataagcc
    42061 catgtacccg ttcgttgtaa ataaagttct tcttgtaaca actcccattt tctcttagaa
    42121 atcataatga cgccatcgtt caatccattt ttagaatccc tagtaatttc tatttcagaa
    42181 tttgaatgaa ctacttcttg caacacttgg tgttagtatc aaatcttaga cagcttttcg
    42241 tagagacaag aataaattaa acttatctac gagaggatga atttttatga cccgatatga
    42301 agaaaatttt aaacaaatga ttgttgaact gaatcaaact ggacgttctg ttcgagggtt
    42361 agcgaaagaa tatggcttat ctgaagcaac gatttacaaa tggaagaatt tatatttacc
    42421 tgatcagtcc acaggactga ctggaaaaga agtagctgaa ctgagaaaag aaaatgctcg
    42481 tttaaatgag gaacttgaaa tcttaaaaaa agccgcagcc atattctctc ggaaaaccta
    42541 aattcgcttg ttcaatttat tgaaaaatgg tgtaaggatt acactgtttc tttgttgtgt
    42601 cggttattag aaatccctag aagtgtctat tatttttata agaataaacc gttgacagct
    42661 acagaaatca gaaataatac gttgaaaaag aagatttcaa caattttttt tacgaataaa
    42721 caacgctatg gtgccacaaa gatccatcaa gttttattaa aagaagggat ttcagtatct
    42781 cttaaacatg tccaaaagct aatgaaacaa ttaaatttaa ggtcgattgt agttaaaaaa
    42841 tatagacctc aaaggtctaa taaaccgatc atttcaaaag agaatctctt aaatcaggac
    42901 ttttctactg aaacgatctg tgagaaatgg gcagctgaca ttacgtacat tcctactaag
    42961 aaaaatggtt ggtgttactt atcttcaatc atggatttac acacgaaaaa aattattagt
    43021 tatacatttt caaaacgaat gactgtggat tgtgtcattc aaacattgaa taaagcaaaa
    43081 atacattatc acattccaga aggaatgatt ctacacactg acttgggcag ccaatacaca
    43141 gcaagagaag tggaacaatg gcttaaaacc aacaaaataa ggcattctta tagtagaaaa
    43201 ggaacacctt atgataatgc tggaatcgaa tctttccatg cctcattgaa aaaagaagaa
    43261 gtctacacga ctagctactc agattttgaa gaagcaaatc gagcgctatt tagctacatt
    43321 gaaggatttt ataaccgaaa tcgaatccat agctcgattc actatctaac cccacaggaa
    43381 tttgaagaat tagcaaaaga aaaaatggct taaccgtctc tactaaaatg tgtccaagat
    43441 attgactcaa atccaacttt acctatattt tctttgaagt ttgttggagt aatagtatcc
    43501 aaaatgaaca cctctcttct ctatacctct attatgaagc gcccatcaaa taaagcaagc
    43561 gttgaggaat aattctatca acacttgctt tattaagctt tcattttgta gtttgactaa
    43621 aaccaataat cttatttcta aactctcgaa aaacttcttg tggctgataa tagtctgcat
    43681 ctatttcaaa tgtttctgag aataattcat tgaatttttc tactgaaata atgattttac
    43741 cattcttctc tcgactgttt tctattattt ctgcttctaa ttcaaataaa tctagtgacg
    43801 aattaaaatc ataaatcctg tcatattgaa caaaaaaatc aagaaaaagt tgctcaaact
    43861 ctttcttatt tatcactagt gtttcaagca gatcaacttt attttcttca gtcattcttc
    43921 caatttcctc actttcgttt tcaaaaatca caaaaatgat attaacttaa aagccactaa
    43981 caaaataaga cttacaaatt aaagggtaat ccaacaaaat aaccattcgc tctacgtact
    44041 acgatttggt agtcctgcct ttcaatcggt aattcataat agtaatttac tgtttctgat
    44101 ttaccacttt caatatactc aggattatcc aatatcatag catactcata aagctcttca
    44161 ccatccttat tttcaatcga ccattgttgc ggacgtatcg gattttctgt atcatttttc
    44221 attgtatagg tcacttgtaa tacacgatca tgctgtgcaa attcatttct tttttcggtc
    44281 agttcaatat ttttaaatgt tagttcaacc ccatctgcct gataagtttc acctattttt
    44341 aaatcttttg ttacaatttt tattggcttt tcttctggaa aatacctggc tttaattgtt
    44401 agataacttc caaaaagaat caatcctagt agcacaaaaa aaattccttt aacgagccac
    44461 tgaaacggga agtaaacttt aaacatcttt tttctcctcc gttttgtatt tggtttttag
    44521 agaacacgat aacttttgat caataccatc caactttttc attatacttg attctagttc
    44581 tgaaattgtt tgttcaagtt taatgctttc aggatcacta aattttttat ttgattgact
    44641 agccaacatt ggtaaatttg aaaccatcac acggaacata tttgctttcg ttccaagagt
    44701 tcctttattc ttctcataaa agctgtcaaa caattttttt gtttcctttg aacaatatac
    44761 tttaatatac ggatcagaca ttcttttccc tctccctgtt tacttaaaaa tccatatcat
    44821 attgattttg ttgtttttga taatcaattc ctcttgctgt ttcttcatac tctctccgag
    44881 ctttttcaat cgtaccatca tcaattgcac gattaaataa ataaagaaca cgttttgttt
    44941 cttgaatata acgcttctta aaattacgtt ttaaagcggg ttcagtatct tgaatgttaa
    45001 attggtcata atcagttgat aaactctctg cgatatcata aacaactttt ttatacacca
    45061 aatttacaca tttcttctta tattttaaag gttcctcttc cactgcaaat ccaaagaatt
    45121 ggtttttatt ctcaccaaaa acatccaata aattttctat tctgtcctct atttcaaatt
    45181 tatatttatc ataaaattct tcataatctt ttgatgatct aagaaatggt atattctcat
    45241 tatctaattc aaagcgttgc gctcgttctt gccaattaaa tctactatcc gctctaccat
    45301 ttaacgattt accaagatat cgaatagcaa tttcagtgag tacctcttca gattgaattt
    45361 gctccgcttt tttattttct gtgaacaaat catcaagata attcatatca tagttttgcc
    45421 ctaaacgctt tccgccaatc tttaagatta acccatcttc agaatctaag agtttgtacc
    45481 caatacgctg atttttggca aaccggtaag tctcaataga atggtttttc ttcaattccg
    45541 catgaaaatc atcataattt ttcgcatact gagcaacttc agaaacagct agttttattt
    45601 tttctcgatt tgaaatctta ttttcagttc taaattcacg ttctttccaa ttttcacgat
    45661 ctgcaactaa atgattatac ttatacatat caagtgggtt aattccatta tcaataagta
    45721 tattatcatt ccaagcctgc aaaactcgaa tatcattctt tcgaatatcc attttctttc
    45781 ctgttcgctg atcgtttggc gaaataccaa agtgattgtg aacatgccct ttgtctgtgt
    45841 gtgtgacaac caaaattgac tggttaggaa acattttttc tgcccactta acacccaact
    45901 catgtgcttt ttcagcggaa atatcttcta gtggatcaaa gctttgtgta aaatgccaaa
    45961 gctttatttt ccctttatca ccaaaaattt cattggttcg tttaaattcc tcaatagcat
    46021 ttaaatcatt cgatacgcca attcctgtca cgagttcaga atcttcttgt ttatttaaca
    46081 tatatgaaat tgtattatga atactcctac tttttgaagc aatttttata atcgagccca
    46141 taacttattc aactcttttt ccaagcgatt caatggatca cttattgatt ttatttgtat
    46201 cattaagtca tttttttcag catatagccg ctttaatcgc tcttgcttag ttgtaaaaga
    46261 taagtaaaca ctctgatgtt cttctttttg tatctcggta tcttttttat ttaactgaac
    46321 acgcaaataa tttgctgttt tcactaattg attcaaattt cttcctattg ctagtaaatg
    46381 aaaattaatt tctttatatt gtcgatcggt atattttaga cttttccctg cgttgtctac
    46441 tgcgattttc ttcacgtaca ttggaacaga taaaccaaaa atgtctgctg ttttttctag
    46501 ctcttggtac tgataatcgt ctactcgaaa ctttatcggc ctattttgtc gtcgactatc
    46561 ttcattacgt ttatatcgct ttctcctttc ttctaatggt agtttactga catcaattgc
    46621 catgcgcact tctcctttgc aatattattt ttaagttcaa aagaagcaag cgaggggaaa
    46681 gggaaccctt ccccgcttgt cgagggagta aactccctac gagcaccctc atgctccgca
    46741 ttttatcgag attagatagc cgataaatca gctacctaac actttcttct tgcgcctctt
    46801 ctcgatagaa aattcgatac gctgtctctc cttttcttct caaaaattgt tggaatttcg
    46861 tttccatcaa ttgatcgctt gcaagaaatt cgtgtactag ggtaaattcg ctattcgcga
    46921 aatttaccgc cttttgccat ttttcttgag tacctttttg attaatttca aaagtttctt
    46981 caaactcttt tactgatgaa attcctgttt tttcatagac atactttccc agttcgggat
    47041 aaagttttct ctccaactcg gcgagttctt ttttcaaatc tgcaattgac ttttgttttt
    47101 tccttgccat ttttcatgct cctttttgta tgtgactaag ttcattcata agctcatttt
    47161 tcatcactaa ttcttcttga atcatcagtt caatataatt tgtgaccgtg attttttcat
    47221 ttgtcgcttt ctttactgag tcgcataatt cggcaagttc taagaaatcc tgcgtactaa
    47281 tctgtagaat taattgcatg acaatcacct ctttattttt taaatagact atcaaacagc
    47341 ggatttggtt tatcagaaat atcctgaaac agtggattat tttcataagt aaatcgttga
    47401 cgtttcttct ccttcacttc ttgttctact atcacttttt cattaggtct ttcttttcgt
    47461 tcctcgacaa tatttatttt ttgcgtctta tctccctgac ttgcttcagc tcttgtttca
    47521 cgtacttcta ccgttcttgg ttgatttgac gcactacctt gtacattttc tcgtacatct
    47581 actgttcgat ttccgctttg actacttgta gtattctgca agttttctcg tacatctatc
    47641 gttctcggtt gatttgacgc actactttgt acattttctc gtacatctac tgttcgattt
    47701 ccattttgac tacttgtagt attctgcaag ttttctcgaa tatctaccgt tcttggttga
    47761 cttgtcccac tactttgtac attttctcgt acatctactg ttcgatttcc attttgacta
    47821 cttgtagtat tttgcaagtt ttctcgaaca tctaccgttc tcggttggct tgtcccacta
    47881 ctttgtacat tttctcgtac atctactgtt cgatttccat tttgactact tgtagtattt
    47941 tgtaagtttt ctcgaacatc tactgagcgc ctatcttgac tacttgtaga attttgtgga
    48001 ttttctttga ctgatttttc taatccggta tttgaatttt tagcttcttg gattctttct
    48061 ttagtcaacg cttctttttc gtccatatta gcgcctgtac gcccttctac acgtttcctt
    48121 aacatttcct cacgattcat tgcttcaggc gtgtattttg cttcctgtcg cttctgatta
    48181 attaattctt cagcagactt agcttgaccg tgcatagcat ttttacgttc ttcaatatct
    48241 tgtttaactt tttgctgaat tgcacttgca ggattaatat ttgattcagc attatttttc
    48301 attgcttcac gcatacgttc agaactagac ataattctat cagcgttttc aactttagcg
    48361 ccatcttttc tatccgaaag acgtgttggc atagaatcag catattttcc agtttcatct
    48421 tctttatttt tagctactat aggtttgcta tttttattaa tagcggacat ggtaccatca
    48481 tctaaacctt ctttgaattt attcttggta tcattagcca tatcacgcat actcttaaat
    48541 ggttttgttg ctctttcact agccattgta gctccatccg aagctaagcc tgataatcta
    48601 cgttcacgag catacccaag cgttttcccc gttttattag ctttttgaga aagtgattga
    48661 ccaaagttgc gttcaggttt tcgttcttct ccttccgctt gatcgtttcc accactattt
    48721 ttcccacctt tagatcggtt cataccacct gttcctttac gaaacagcat tgcacccatg
    48781 ccaaaagcag aagcaagttg cccatagcct tctttgagtc caatatccac accaaagtaa
    48841 cgcatgactg ttccactgcc tttgattaaa acaaacacag cacagatata agcaattgtt
    48901 tttataaaga tatttgttga gataccttca ccagcattta gataattgac aaacattgca
    48961 aacatagaca atccgaaccc ttgaaatccg actgtcaaat aacactgtaa aatatctgac
    49021 aaaacttgtt ttgatcgttg acctgtctct aagtcagtag caaataccaa aactccaagt
    49081 acacgtttaa atgctaactc gagtattgct gtaattataa tgaaagcact aaaaacatac
    49141 gctactgcta aagcaatcaa tccaaatgaa attccccaca aattcgcttg atagcgataa
    49201 tatcctgatt tgataccatc aacaaaggtt gacaaaaaat tatctgaaaa tttagtagca
    49261 acaaattcat tatcagaatt ttcaactaat tcataacgca ggttatcagc tgttgggttc
    49321 tctttttcca ttttatcaat tacattatct gtcaatactt gcgtaagatc cgttttccaa
    49381 aaattttctt ttgttagatt attccggtca ttcgttttgt taatcattga atactgatct
    49441 gttttattga tataagctaa atcagtgacc ccttgttcaa tcagcgacca cgccacgcct
    49501 tcgtccgaat ttgtaatcgt agtcgtatca ttataaaatg ttttagaaaa ctctattcca
    49561 ctgtgaatca aagtcggcat taaaagaatc aatgctactg acattacaac attcattcca
    49621 actgatttta gatcaaccgt tcctttacct gtaatcattt tataaccaat aatcactagt
    49681 gaaagtatca ttaagccaac aacaatggta cttaaaactg attgatagac tttattcaat
    49741 ccggtacttt ctacaaagct aaacaaatct aaaacctcgg gaatcatatt ttgaatacca
    49801 tcgacaatag cgaacattga ttttataaca gaccagccta tccacatacc gaactggctg
    49861 taaaaatttc cgttatattt tttaagataa ttctgataaa gtggattagt taaaaactca
    49921 gtttgactct cagtatcatc aaaccagttg aaaatactgc cttctgcaac gttactcgta
    49981 aaaataatca tagctatgag aataagaaaa ctaatcaaca accaatttat ttttctatta
    50041 tcaatctttt ttttaattat tttcattgtt acctccctca gcccattttt ttaggctctc
    50101 agaaagcttc tgagccattt ttttattaac gatgatgtga gttacgtaat catcattaac
    50161 agctcttaaa tctagaacaa tagtatttga gcagatactc tcgattaact caagagtatc
    50221 tgcgttatga tcaagacagt aaatcttatc tactagatga ttttcaatca aaataacccc
    50281 tcccgtagtc aaagttctca attttatgaa gatatccctc tacttcattt aaatcaattc
    50341 tattcttatt gctgactaac ccgttgtaaa attctttttg tagattatat ttatctgttt
    50401 cttgaatctt tttatataaa tcaaccaggg agtccctgtc tttaaaaact tgcttgaatt
    50461 gttcgcttgt atatcggttt tcattaattg caacaactgc ttgaatttca ggccattttt
    50521 ctttcaactt aaaataacgg ggaacgctga aatagttctc aaaaaagaag tctcgtgctt
    50581 catagtattc tctattttgt ctttttatat cctcgacaat ttcgtatcgt gtagagatct
    50641 tcaaagctga actttcgtta atttctgttc cttttcgaaa gactttcact tttgaagggc
    50701 gttcaatttt ataatttatc ccctttttac ttgaataact tttgatacga ccatcaaatt
    50761 gaaccatatc tccttttttt aaccacccaa attttagaaa ttgtttagtt aaattcatcc
    50821 aaatgtggtc tgtgaccaac tctaagttat ccccttgaac aatttttaaa ttcgataaca
    50881 taaaagtagc attttcatac tcttgaccaa acttgtattt atccttttta tatccgttaa
    50941 attcaaaggt accttgaaat gtatgccgtt tcttatctcc taattttttc aatttttctc
    51001 tcaaaataat caactccatc atttaatata tttttgtgat ggtagatact ctcgattaac
    51061 acaagagtat ctgcgttgta atcaagacaa taaatttgat atattaaccg tttttcaatc
    51121 atattattaa tcctttctaa cctatttttt tcagtgtctc tagcatatcc agtctactag
    51181 ctttttcttg cttagctatg tcctcccagt ggttcctagc tgtggtgttg ataaacttca
    51241 tttcatcaat ttcttcaccg agattcagtt tttcatttat agaattaaaa agtcttgtta
    51301 gcattttgtt tgttatatca aaatagtctt gacctcgaat ttctatttta tattctcttt
    51361 caattgaatc tttcatacta gcaatcaact taagatactt ttctctttga acttcagtat
    51421 atctatcacc tagtctggta attatttgaa ttcctttctg atttataata ttttcaaaaa
    51481 aggaattctg atcttgatta atctcttcta tactatcctt atcttgatta gtttgatctt
    51541 gactattctg atcttgactt aactgtgtat ccgatttgac gtcgcatggt ataccagctg
    51601 gataccattt ttccatcaga tcaactctta atggttctac ttgaccagac tgcaaaatca
    51661 tatcaaattt tattggcttt agctttgaga aaaattctgg ttttaagttc aataacttga
    51721 atcgataaat agaaggttta tacctatcga ttcgtatatt ttgattttgt aaccagtggg
    51781 gtagaaacgc taacaaatct tcatttaaaa aaaatacaaa accttttgta aaaagtatct
    51841 ttacatcatc atcgggtgtt ccgagcattt tcgtgtatgg ataagcttcg acaattccgt
    51901 catcatctgc gtttgtgttc agatatacgt ataataattt tgctgaatct gacatcttca
    51961 taaaacttgc attatttaaa aatgatttag ccagcattcg tttttctgcc ataaaaatca
    52021 cacttcttcc tatttgaatg ttaaaatgta gtcaaataaa gtttagctag aactttatta
    52081 ttgagcgttc ctagtggtct gcaaactaac gggaacactc ttttttattc ttattaaaac
    52141 cagcaatact agttcacctt ctttcatcct tttacatcca attaaatttg atgctgtagc
    52201 atccattttt ttacctcttc ttttgaatat agttcaattg tgtcaaccac gataataggt
    52261 aatcctaacc ttttaaactt cagaaaagtt ccatatgata cgtttagaaa ttttgccatt
    52321 tcttttccct taagaaaagg tcgttctaat ccgctgtcta ttcttgcttg atcaatagct
    52381 tcttttgtca cttcaaacac atgtgtcttc aactgatttg tttgatcagt attcaacatt
    52441 acactgactc cgatttgctc cattaaaaat tcccactttc atattttcat caataagcca
    52501 actcgccaag ttgtttgtta ataatctgat ttcaataacc aacctattat tttttgataa
    52561 acatttttcg acacactttg aacttcgaag cattcaattt ttttaagagt ttgccttgaa
    52621 attccaatta attctgctgc tttagttttc gtaatcatca actttcctcg tctctctcga
    52681 attcttatac taaaatcctc attaatttga aacataaaca tccctccatt tttatttttg
    52741 catttatccg tttatccgat gtcggataaa tagattttag tatatattat tttgatagtc
    52801 aattaaaaat atacattttg gataaaattg ttcatttttt tatccaaatc atatattata
    52861 gatagtaaga ggtgaacttc attgactcaa aaaaacagaa ttaaagaaac tcgcgaagaa
    52921 cagaatttaa cacttaaaga acttagcaat ctgtcggata ttccgtatca aactttgaga
    52981 aactatgaga ttggtaaaag aaaacccaga aatgatgaag tttggtggaa gttaggtacg
    53041 attttaaacg tccgtgggcc ctacttaaaa ggagaagata gttttaaaac aaatgatgaa
    53101 ttgcatattt attatctaaa aaaaagtcat acaaattttg aactgtctaa gaaagaagaa
    53161 attatagata taatagataa actaaacgaa gacggtttag atgaagcctt acggcagtta
    53221 gcactattat caaaaataga tgatttcaag cggtaactta cttatcatca tgtagactat
    53281 caggtatcat aaactaattc ctcaatcagc caactcgcca agttatcaga ttggagagat
    53341 tagttatgtc aatacaaaag tacaaaacaa aaagcggtac acgatatagt gtccgcttat
    53401 atgttcgtaa agatgaaaat gggaagcaag aatactatgt aaaaaaaggc ttcaaaactg
    53461 aaaaagaagc caagttacac gaagcaagaa aaaaggtcga gattgaagat atgggctatc
    53521 acagaccttc taatgactta tttagaacag tctatgaaga atggttgccg tcttataaaa
    53581 atcgtgtaca agaaacgact tatcaacgaa caaaagacct ttttcgcttg catatcctgc
    53641 caaagttcgg agacaaatcg atttctaaga ttactcctat ttactgtcag aatgcaatca
    53701 atgaatgggc tgtaaaatat acaaatatca agcaacttaa atcctacagc tctcaaatat
    53761 ttgagtatgc aatcttcgca gaattgttac agcgtaaccc tatgacaaat accaaactgc
    53821 caaaacaaga aaagaaagaa tccgaaaatt atttctcact agaagaatta aaagagtttt
    53881 tggaaattct caataaagaa gagtctttaa aacatatcct gatctttcaa cttttaatta
    53941 ctaccggtgt tcgcaaaggt gaattatcag ccctacgctg ggcagatatt aattttgaag
    54001 aacagttact acacatcgga aaaagttatg caacaattcg cactgaagat ccgaatgcta
    54061 ctagaaaaac aatcaggatt cagaagaata caaaaaatgt ctcttccgaa cgaattttac
    54121 cgattgatac tcaaaccatc gaaatgctga aactttggaa aaaagagcaa gcagaggtac
    54181 ttttacaatt cggcattaat gcaaatacca aaaagcaact tatctttacc tatgtaaatg
    54241 caaatggcga tgttaaccaa cctttacacg cagattattc caataatatt atgagacgtt
    54301 tagagaagaa atataaattt aagcacgtta ctattcatgg attgcgacac actcacgcca
    54361 ctttactttt agaaggcggt gcgagcatta aagaagcaca agatcgattg ggtcataaaa
    54421 atgctgaaac tacgctcaat acttattccc atgtaactga aaaagcgcaa cgaaatgcgg
    54481 tagacaagtt tattgcttac actggattat agacaaaaaa gttgccgtca ttaccttttt
    54541 cattaccaca acgaaaaaaa gcaccttcca actgaatgga aagtgcttga aatcgttggt
    54601 ataacaacga ttaacgctta gagaattgtg aagctttacg agctttctta agacctggtt
    54661 ttttacgttc gaccatacgt gcgtcacgag taagtaagcc agcacgttta agagctaaac
    54721 ggaagtcagg atcaacttct agcaatgcac gagcgatacc atgacggata gctcctgatt
    54781 gtccagcgta tcctccgccg tttacgttaa caaatacgtc atatgcgcct tttgtttcag
    54841 taacagcgaa aggttgattg attacttcac gcaagtcagc atgtggaatg tattcttcaa
    54901 catctttttt atttacagta attttgccag ttcctggtac tagacgtacg cgagcaactg
    54961 cgtttttacg acggcctgtg ccgatatatt gaacttgtgc caatgaaatt ccctcctatt
    55021 agattaagtt tgtgatgtct aaaacttctg gttgttgtgc tgcatgtgga tgttctgctc
    55081 caccgtatac gttcaatttt gtaaattgtt tgcggcctaa agtgttttta ggaagcatac
    55141 cttttacaga agtttcgatc aaacgacgag aatttttagc acgcaattcg ccagcagtga
    55201 ttgatttcaa tcctcctggg tagttgctgt gacggtaata aattttgtca gtcgcttttt
    55261 tacctgttaa tttcactttg tctgcattga tgacgatgac gaaatcgcca gtatccaaat
    55321 gaggtgtgaa agttggttta tttttaccac gtagtacaga tgcaacaact gttgaaagac
    55381 gtcccaatgg aacatcagtt gcgtctacta cataccattt acgttctact tcgcctggtt
    55441 tggccatata tgttgtacgc acgttatttt cctccaattt aagttctgat gtttgacata
    55501 cacttcgagt ttccggggct ctttgtgggg caaacaatac catttaacat attacccgct
    55561 aatctagtca atgtcaacgt ttttctgctt gattgaaaaa tttatatgaa actttacttc
    55621 ttttctttct tttatataaa agggtcgttt cctgtcaaaa tgaaaaacaa aaagaggctg
    55681 tgacaaaagt cttgtcacaa ccccttattt tgaataaacg gtgttctcct gccaactcct
    55741 cggtcacaag tcacaatatc cataaaacat aagaagctgt tttttaaaat tgtttcttgt
    55801 gactcggagc tgaacggcag gcttacaacc tcttggtaaa cggtgttcaa tcagctgacc
    55861 ctcggtatta gctcaaaaaa cggcaaaata tgaggaacta ttttgacgtt tgtttctcta
    55921 atactcaggt caaaacgctg atttcacaac ctctttttcg gtcaagttca acaacagttt
    55981 ttacgcgtcg atctctggcg ctttgcccaa atgagcttgg atcatccaga tacgtttttc
    56041 tgtggctgtt ttgaattcga taaagatatc ttgtgttgga tcgtcgcctt cttctccaga
    56101 aacttcgatt cctttttggt aaagatctgc tagataacga tagcctgcaa caagtgtttc
    56161 caaacgttct ggaatagtac gatcccagcg gccaatttca tcagggattt ttgtgttatc
    56221 tgcaaattca cgcaatgtag aataaggtga accgtctaat gtgatcaagc gttcggatac
    56281 ttcatctaac tgagcgttca aatcatccat gaactcatcc atcattgggt gcaatgtaag
    56341 gaaacctggt cctctcatgt accaatgtgt ttggtgaaca acaacagaca tttggcttag
    56401 atctgcaact aattgattta atacttcttt ggtttgttgg aatttcatct ttcttgcctc
    56461 ctaacatttt cttacactta aaataatagt agactttcaa tgaaaagtac aacaaaatca
    56521 tttacctgag aacgattttc agttcgcttt tttatccgta aagccaatca tttttcagaa
    56581 tcagctaatt cttctcgcag ttgagcaaat tgctgataag tctgtgctaa atgcttttgt
    56641 gtcgaaacaa ataatggata gattttctga tattttttat gatcagtttc ttgtactcca
    56701 acttgctctt tcaattctat caattcctgt gcttcactga tactttggat ctttccgatg
    56761 cttctccagc ctaaaatcac agctcctaat gcggatgctt ctgtgacagt agggaaaaca
    56821 agcgggtaac ccagtacatc agccatcatc tgacgaaaaa tcggagattg agcaaacccg
    56881 cctgtagcac ggatctctgt gagctgattt tcctggcaaa ctccttttaa aatccgataa
    56941 aggttgagac agatcccttc tagaatcgcc ttcatcattt ctttttctgt atgttgccgc
    57001 tgtaaaccga taaaactgcc aaacgcatct gcgtcccaaa gcggtgctcg ctcaccaagt
    57061 aaatagggat gaaaaatcag accattggca cccgctggca caaaagcgat agccgaaagc
    57121 agtgcatcat atggattttc tcctttttct ttagcagatt gaacgacttc ctgtaaaaat
    57181 gtatgccctg cccaatcaaa gatgccagca ccattgctag tcgctcctcc cactacccaa
    57241 tgtttctgat ccagaacata acaaaacgtc tccatttctg gatggaactg aggctgagta
    57301 gtaataaaac gaagtgctcc gctcgttcct acggtcaaag cggcgatcgt atcaccaaaa
    57361 gcacctaacc ctagattaga aagcggcccg tctgcccctc ccaaaacaaa tgatatatca
    57421 tttggcaaac ctagttctgc tgctgttttt gatggtagac ctgttacttg ataggtggaa
    57481 ggaaagactt gcggcaattg ctctattcga atgttcaagt agtcaagcac ttcttctgcc
    57541 cattggaatt catggatatc aaaatatcca gttcctgaag ctgttccgta gtcgctgatc
    57601 agttcgccaa acaatctata aaagatatag tctttgatac cgacaaaata agcagttttt
    57661 ttgaataatt caggttggct gttttgcagc cacttgattt tgttcaatgg tgtcattgga
    57721 tgaatcggcg tcccagtctg ccgataaaat tctttgccaa gcacggtata tttcagtttt
    57781 tctgcttcgt ccgctgctcg gttatctgcc caagtgatca ttcgagataa cggtgttttc
    57841 tcttcatcca acaatatcag gccatgcatc gcagaggaga aggagacaaa ttgaatgatt
    57901 gtgtctgaag gcaactgttt aattacttct tttataacgg tgcagacacc ttgaaagatc
    57961 aattcctgat cttgttctgc catcccttgt gtttcttgga tcaaagggta gcgaaaataa
    58021 gcggatgctg cttcttgggc ttcatctgtg aaagcaactg ctttggtttg tgtggttccg
    58081 atatctaatc cgattgaaac gttcattttt tcacctcaaa ttttatgtat gtacaaaaat
    58141 ttagtttaag cttgcgtatc ttggttttga aaagggggag atggcgtgtt actttatttt
    58201 atcattggtt gctgtatcgg atcattttta tgtttaaccg cccagcggat tccgttaggt
    58261 cactctatta tttatcctag atctcattgt gtcaaatgct gtcgttcgct ttcttggtat
    58321 gaattgattc cgattctctc gatcatcgtc caacgatttc gctgccgcta ttgcaggtgt
    58381 cggttgccct tctactattt gttggcagaa gccttatgtg gtggtctttt tgcctggttc
    58441 tttacttttt cttccgcaag aaatttttcg acgttcatat ggatgctttc ggctttgcta
    58501 ttttcgttga tggatttatt ttacttcatg gtccattctc acacgctatt ctgttcttgg
    58561 gcaattttat ggattttttg gttgcaggcc ggcgtcttcc aatggcaaag tgtgctgtta
    58621 acgtttatcg taggcggtgt gtgccttcgc tatggtcaat cctatctcgg agctggcgat
    58681 actctgttga tgctttcttg gagtggtggc ttgtctctag aagagttgct tcagatcttg
    58741 tttcttgcta gtctgtttgg aatatccgtt ttttctgttt actttatctg tcataaaaaa
    58801 aagttggaaa agctgccttt cattcctttt ttgagcagtg cgttgctgat tgtccttcat
    58861 cttaggtatt gaaaaaaggt tgtgacaaac gacttgtcac aacctctgat atatagtgtt
    58921 ctcttaccaa atccttgtga cttggagcta ggcgacaggt tcacaacctc tccactaaat
    58981 ggtgttcaat cagctgaccc tcagtattag ctcaaaatgc tggttttaca acctctgata
    59041 tacggtgttc cataagtagc tttttcggct tcttatttct tgacgcccca atgtcgacga
    59101 aggaaacctg cacgtccaga accttctcga taaagattgt aatggagctt gtttttcttg
    59161 taataatcct gatggtaatc ttctgcagga taaaattcgc ttcttggttc gatttttgtc
    59221 acgattggct tatcgaatcg cccgctgtct tgcaatgctt gttttgaacg ctctgcaata
    59281 tttcgttctt cttcatcatt atagtagatc actggacgat aagaatcacc gcgatcagcg
    59341 aactgtccta atgcgtcagt cggatcggtt tgctgccaat agatttccac caactgatca
    59401 taagaaataa cttctggatc atattcgatc tctactgctt ctgtatgccc tgttgtgcct
    59461 gttgttactt gttcataagt tggatttggt acatgcccgc cagtataacc ggatgtcaca
    59521 gaaatgatcc ctggctgctc ttcaaatggt ttgaccatac accaaaagca tccgcctgcg
    59581 aaaactgctt tttttgtcat ataaaatccc ccttttttct catcatacct tgatttccaa
    59641 aaggaggata acgttttgct tgtgacagaa aaaacggaaa ctattatata cgtgatacgg
    59701 cttctgataa atgccaaaac gaacgtactt gatcaaaaac ggttaaatca ggaatcacat
    59761 attcagcaga aggaagattt atgttttcac ctattcccaa tacatgcatg ttaccagcca
    59821 aagctgcttg acaaccagct tctgaatctt caatgaccaa gcatgcattt ggcggtacat
    59881 tcaattgctg tgctcctttg agaaaaactt ctggatcagg ttttgctttt gatacttgcg
    59941 tgccgtcaat aaggacatca aaataacttg tcaaattcgt tttttctaaa atgaggcgtg
    60001 catttttgct tgctgatccc aatccgatct tgatgtttgt ttttttcaag tactcaagaa
    60061 cagctattgc accaggcaaa acggatgttt catccatttt ttgaatcgct tgaagatata
    60121 gattgttttt ttgctcagca aaggctgatt tctctttttc tgagaatttc tgttccattt
    60181 ttccaaatga cagcaatcgc tctagtgact cggttctgga tattcctttc agttgctcgt
    60241 tttctttctc agtgaatgga atggacagct ggttagctaa aaccagccac gcttcgtaat
    60301 gataacgagc tgtgtctaca agaacgccat ctaaatcgaa tagtgctgct ttgattttca
    60361 tcgattacct ccttgaaaat gaacgacttg aagtaaagat gcgatgtttt tagctgtgcg
    60421 atgaagatta tcagtggctt gctgtaaagc ttcttgtaaa ggcacagctg caggaaggat
    60481 cggaaaaacg gccgaaatgc caacatctgc tgctttttcg cttcctttac caacacttcc
    60541 gcaaatagct atcacaggaa cgccctctgg tactcttcta gcaatcccaa ctggcgcttt
    60601 tccttttaga ctttgtccat ctagacgtcc ttcgcctacg attacgaggt ctgcttgctg
    60661 tacccgttta tcgaactcca gtaaatccaa tacgtagtcg atgccagaga ctattttccc
    60721 tgaagcaaat gctaacagtc ctgcacccat tccaccacca gcactactgc ccgatgcctc
    60781 gattacttga ggggcaaatc tcatataaaa atcatgcatg gcttggtcag ccactgctaa
    60841 ttcattttct ttcaagcctt tttgtggtcc gaaaacaaaa gaagcgcctt cttttccgca
    60901 taaaagatta gtaacatcag taatgacagt gattttggct ttaatcagct caataggcac
    60961 gttcgtttta tcaactgtag caattttacc tagattttct cccagtgctt ctactttttg
    61021 attatcttga tcgtaaaaag cataacctag accttctgcc atgccgatgc cgccatcgtt
    61081 ggtactactt ccgccaacgc cgatgatgat gtgtcgaaca ccttgttgca acaattgtcg
    61141 tatcagttct cctactcctc gcgtggataa cctaagtggc tgttgttggt ttagtgggac
    61201 atctttcaat ccgacgattt ctgccatttc aaaaatcgca gtttgaccgt ctgaagcgta
    61261 ctggatttct ttgtttttgc caaatgcatt agtaacgact gctgtttgcc gcttcaacct
    61321 taaactgtct gctaatgatg aaaccgttcc ttctcctcca tcgcctatag gtagcagatc
    61381 atattcagcc tgaacaaaaa cttcttgaaa acctgattga atggcttgtg ctgcctctaa
    61441 ggctgtcaga ctttctttga aagaatctgg cgcaatcaga atacgcatta ttttcccctc
    61501 cgttccaaga tcagttcttt ttccagctgg tattggtctc cattgacaaa aataggtaat
    61561 gtttctttcg tctctttttt tattactatt tgtttttttg tcaaaacaaa tagcaacctg
    61621 tgatttttcc aaataaaagg aaaagaaatt ttttcccatg ctgaaggaag tcttggagaa
    61681 atagaaagag ttccattcgt tactgtaata cctgaaaaac caaatataac tgctagccat
    61741 agtgctccta atgaagcagc atgaattccg tcatctgatg aatgcggatc tggtcctaaa
    61801 tcaatcaggc acgcttcttg gaataaatga tacgcccatt ccatttcttg gatacggcaa
    61861 gcctctatgg cgtgaatcgc tttactcaac gatgagtcgt ggattgtttt gttttcatag
    61921 taatgcaaat tcttagaaac gattggttga gaaaaatact caggtaataa gtataacagc
    61981 atgacaagat ctgcttgctt gctgacttgg agttcattta cttcgctacg ggcataatca
    62041 agtaaaatag actggctgcc aggacgttct ttgtaagtgg tcaaatcaat aactggctta
    62101 ctgagatacg tgtcatcttg cggaatcagc tgttctttgt taggcactgg caaatataac
    62161 ttatctaaaa aattttgaca ttctttcaaa aaaagcggat cgccagcttg atatttaaca
    62221 gctaaggcca cattataatg cgccagatag ttcgtatatg cattattgtc gatatattct
    62281 gtgtattcat ctggaccaat gactctgtgt atctctaaat gatcatcgac ttttacagct
    62341 ctgctcagcc aaaaagctgc tgtttcatga atgagcgttt ttccctttgt ttctaaaaac
    62401 gattgatcct ctgttgcttg gacatactct tgaacggcat aagcaaggtc tgcactgata
    62461 tgatgttctg cggcagctga agcaacttct tgtcttgttc cggttttgat attcaatgca
    62521 gcaaatttgg gtgtctcttc ctgaccagtg tgtgcgcttt cccatgggaa aagtgcacct
    62581 tgatagtgat aatctcttgc tttttgccgt gcgccttcta atcgatcata acggtacagc
    62641 agcaaattct ttgctacttc aggaaactga tataaaaaga aaggcaggat aaaaatttcc
    62701 gtatcccaga aaacatgccc tttataacct tcgccagtta gtcccttcgc ccctacacta
    62761 acacttggat cattgcgggg agtcataatc tgtaaatggt aagcagcgaa gtccatcgct
    62821 aactgatcga aagaagaatc gccttggatc gttatccgat gctgatgcca aaaatctgtc
    62881 caataagaca tcgactgctc taaaatttct gtataactaa cgcttttctg ggcttgggca
    62941 atacttttct taaacgggtc tgtttgctga agagaggtag agagcacgat gatcttctcc
    63001 agcgtaaagg acgtattttt tctgatcttt tctgaaaagg aagcggtgat ccggcgattt
    63061 tttgcttgga atacacctgc tttattgaat ttagctgcaa tcccaatatc aattttactt
    63121 tctgttgtct ggtaggatgc actgatcaaa tcgtcaccaa atactcgcag ttctttttca
    63181 accaactgct gtgtaccaaa attggtttgc tgtccatcga tacccgtttt cacatctact
    63241 tggcagtctt cggtcaacgg cttgatgacc actttcaggg ctgcctgatg gagattattt
    63301 tgatcagcaa cacgacaagt aatgacttcc actttttttc cttgagcagt ttcaatgagc
    63361 gcatagcgtt taagctctcc catttctaaa tctagtgccc gctcgtatgc aagaactttc
    63421 atcgtctcaa gagaaaaatg ttcaccgtcg atttttattt cccatctgat gacatctggg
    63481 agattcacta actcggctga ttctgctcct aaaggtcggt tatatacacc agctgcaaac
    63541 attcccctta cttgattccg atagtcttcc tcctggcttc ctctgatacc aaaaaatcca
    63601 tttccaatgg tcatctgact cgcatactta ttgatatact ctaaatcaaa ctgtttttct
    63661 tctactttca taaggtaata acttctcctg tttctgccga acgatataaa ttttccacca
    63721 gattctggat gacatatcct tgccagccat ctgcaatcat ctgagtctgg tcaccgagcg
    63781 cccgattcac aaaatgagcc atacttagtt catgtgggtc attaactggc gtggtctttt
    63841 gtaaggaaac cagctttcca tctacatctt cgaatagttc gcctggatac agattagcac
    63901 ctgcctgatc gccacaaaaa gccacattca gtttgtcttc tctgatattc aaagcaaacg
    63961 aagtattcag ttggatgatc ttgccgtttt ctaattccag tgtgccaaaa attgcatctt
    64021 ctactgtgaa tttgcttgga tcccatttcc cgaatttccc tgaatttttt ttcgtaccaa
    64081 ttttttggaa gctgtacgcc cgaacgcttt ttactttagg aaatccagta atatacatcg
    64141 ctgtatcaag catgtgaatg ccataatcga tcaaaggccc gcctccttga agttctttgt
    64201 cgataaacgt tccccagcct ggaacaccag accgacgaag cgcattcgct tctacgtaat
    64261 aaatatcccc gagaacatca agatgattct tgatcattgt tgcttcgtca gaaaaacgat
    64321 gctggaatcc ataagccaaa atctgcccgt ttttatcggc tgtctctgcc atctttcttg
    64381 cttgatcagc tgtcatagct ggtggtttct cgcacatcac tgaagcatta gcttcgaggg
    64441 cagccaatac atgttcgaag tgaaagcgat tgggtgtaca gacactcacg atatcgggag
    64501 aaatctcatt cagcatttgt gtaactgatg tatacgcatg agaaaatcct gtacgtcggc
    64561 aaaagtcttc tgctcgctgg ctgactggat caaccacagc ggccaattct aagacatctg
    64621 atcttttttg ataataagca gcatgtactt tttctgctac ttgtccagcg cctatgattg
    64681 ctactttctt catttatttc tctctccttt gcttatttac ttattgttat tctttctcta
    64741 ttctttctct aaatcattta aatgacgcgc tgtttccaga cagtttttca agtattgcaa
    64801 tgattcctga taaattttca cttcattttc tcctcgcaaa cgacattcat ataccatata
    64861 accttcatac tcattttgaa gtagcgtttg aaaatggcga gtaaaatcaa ttgcgccaga
    64921 tcctggttgg tagcgatgat tatctgctaa atggatatga cccacatact ctttttgcgt
    64981 agtcaatgct tttgaaatat catcttcttc aatattcata tgataaaaat cagcgatgat
    65041 ctgcacatgt ttcaattgat tagagtcaat gtaatgacgc gcatccgcta acaaattgat
    65101 catatggtct tggtatcggt tcaaaggctc caaataaata accgtacctg tttcttcggc
    65161 tactttatct aaataacgaa gtgattcgct gactgcttta tagtctcctt ctttgcttcg
    65221 gggtgaaacc atcggcggta atcgataagt gaacattccc caagctgctg ggataacgat
    65281 tcctttgcct ccaacctcgc ttagtgcacg caaaatctca gcaatttgac gtacaccatt
    65341 aagacgccgt tcttcgataa agtcaccgat ccacccatcg tagccgttac aagctgtcac
    65401 tactgggatc cctgtttctt tgattgcctg tttgactgtg tcgatatttt ctattaacaa
    65461 cttaccgtcg atttcgtatt cttcaaatcc acagtctttg ataaatctaa atttttctaa
    65521 aatgtctctt gggaaaaatg cttgatcttg cgtaccgaat ttcattgttc tcctcctcgg
    65581 acttgaacgc ccattttgat actttcttct gggtgctggt ctacataacg catgtaagct
    65641 tctgcgcttt ctgcaaatgg cacaactgga tcaatgattt cttcacaatc caagtaaccg
    65701 ttcatcaata attcccaaca tgtgtcctcg attcgtttac ggttccatct tgggtaatct
    65761 gggtttggtt cactagatgc tcgagcaaag acgatttttg cattattgaa atgtgcttcg
    65821 cgaccaagat taaacccagc tggaaaaggt ttagcaaagg caacataaga aatgatcccg
    65881 ccatagccga tccctattaa agaagcttgt aatgcggcag cactgccact cgtttcaata
    65941 actgaatcta ctccacgttt atctgtcaat tcctttagac gaaaaccgac atctgctttc
    66001 ataggatcta gcgtgtaatc ggcaccgtgt ttttctgcta attctctacg ctgcgctatg
    66061 ggatcgatcc caacgatggt agtagcacct gcttttttag ctaattgaat cgcaatttgc
    66121 ccgatagcgc ctaaaccgaa gattgctaca gcatcacctg ctcgaacatg tgcttcccgg
    66181 ataccaccta aagcgaattg agcaggatcg taacatactg catttttcca ttgatccaac
    66241 cgatcaagtt tacgtagttt ataattatca acaccgtttg taatcagcgt ttcacgaatg
    66301 ggtccataag tgcagactaa ctctcctttt tgatactctg tcaccaaact gcccgtttct
    66361 tcgatcgtac cgacaatcat atttcctaat tgaaattcgc caaataccac accgcgttgg
    66421 cttccttctt ctcttggcaa gaataggcgc cattcttctg aaaattcttc atcgataaat
    66481 ggacttaatc ctctaaagtc gacaatttct gttcctggtt ttggagtagc gaaaattact
    66541 cggatacgta cttcgttctt ttcgatctca cggtcttcgt aatctttgaa tccggctatt
    66601 cttggttcta atgcaactaa ttttttcatc ttttctttcc tctttctttt ctttttatcc
    66661 ttttacgccg ccttcgacta aatcaccttt aataaatcgt tcagataacg catacataat
    66721 gatgactggt aaagcggtca ccaatgaagc ggccatcatt cgtccccaaa tgtagtctgg
    66781 tgtactgaat aatgtgttca aaccgattgg taaagtaaat ttttcggagg tcgacaggaa
    66841 aatcgaagca aataaataat cattccacga aaccataaag caataaacga agacagaaat
    66901 gattccagaa atagccaatg gtataatgat ccgaataatg atctggatcc ggctaagacc
    66961 atcgatcatt gctgcttctt caatatcagt cggaatcgtg tcaaaataac tttttagcat
    67021 gaatatcgca gtaggaagtg tttgaacgac catcgtgata atcagtgctg tattggtatc
    67081 atacaaacct agaccggaaa tgattttaaa taatggaaca acgatcaaaa taccggaaaa
    67141 catataaacg gtgtaaaagc tagcattgat tttcgagcga gctttgaagc gtagttttga
    67201 caaagcgtat gccccgctga tcccaatcac tactgcagtt acggaggcta tcaaggagat
    67261 cactaaacta tttttgaaat acatgatgaa tggaaaaatc tcagcattga aaatatcctg
    67321 ataatgttca aaagtccatt ctttcggaaa aatagtttgt gtcgttgcaa ttgcttcttg
    67381 tgaatccttg aatgatgtca tcagcatgat caaaaatgga aacaaattga cagctaatag
    67441 caacaaaatc gtcgcgtaaa ataagatttt cctgctcttt ttatttttca tttcaagtcc
    67501 accttctttc gtgagagcaa gacgaccgct gcaataatga tgaacaatag aatcgatata
    67561 gctgctgctt ttccaagatc attgaacgca aaggctgtct gatacaaata aacgcctaag
    67621 atattgactt tattcgtcag tagatagaca tctgtaaaca tatagaacat ccagatagat
    67681 cgtaaaacaa tcacagttgc tagtactggt ttgattgccg gcagtgtcac gatcttgaac
    67741 ttctgccaag catttgcacc gtccatttca gctgcttcat aaagcgtttt gtcgactgtt
    67801 tgcaaaatag ccaaaaatga aataaacgca tacggatagt atctccagat agcaaacaaa
    67861 acgaccataa agaagctagc aactggctgg tcgaaccaca gcggtgcttc gttgaaaagc
    67921 tgcaacctat ctactaacag atcattgacg attccataac tattattgaa catatatttc
    67981 caagcaaaaa tcaaagaaat agatggcgta acataactta ataaaatcag tgaacgcacc
    68041 gttttcctaa atctgaactt gcggttaagc aaaatagcta cggctaatcc taaagctgta
    68101 ctgcctgcta caactaagaa tgtgtaagca actgttaaac ctaaagaacg ataaaattca
    68161 ctatcactta aaatttcaag ataattgctt aatccgataa aaacggcgtc tgagttagga
    68221 ttcagcggca tatcgaaaaa actgatctga atattggaaa gcattggaat cagcactaaa
    68281 acagctaata aaagcatgct tggtgctaaa agtcccatgg ctaattttaa gtcagaatgt
    68341 ttccttggac gattcattga aacctccccc tgataatctg ccaatagcta tctacttttt
    68401 tcgaacacca ttggcagaac ttcttgttat ttcgtatttt tttgtgcgtc agctaaagct
    68461 tgatcgacat cttcgtttcc gacagttact tggttcactg cttttccgat cacacctgag
    68521 cttgtgatat ctcccatttt cgtgaaattc ttttccccga ctagtccaaa gacttgtact
    68581 tcatcaaaag cactagcaat ctcagatggc agctcgccaa aagacttgat gacttcattt
    68641 tctttgtaac catccagttc gactacttgt ttattcactg gttgagcacc accaggagac
    68701 atcaagaccc acttttccat gtttttcggt tgagataaga aagctgtgaa tgcttcagca
    68761 gcctcttttt gtttctcgtc tagaccagaa gaaatcgtca atccagatac tgtgccatag
    68821 acagcttgat ctttttgtgt tgggatagca aaaccgatat tttctgagtt ccccgcttca
    68881 taaacagaag gcaaaatgta agttgaatag attgccattg gtgctgttcc attcatgaaa
    68941 gcatctttga tttctgtcac atcattagag cctggcatcg tgtattggga taagttttga
    69001 taaaacgaca atgcttctct catcttttcc gtatcgatcg ttacctcgcc ttcatcatcc
    69061 aaaacatttg ctccatttga caaagcaaat tgagagaacg cttgctcact cattgttcct
    69121 tcagcagtag gcatagcaat tccatattgt ttattctctt tatctgtgaa atgttgagca
    69181 atttttaaaa tatcatccca attttctggt tctgaaaaac cagcttctga taatttttct
    69241 ttgtcatacc aaataccttg aacccagccg ctaattggtg cagcaatata gctttttcca
    69301 tcttctgaac gaacaaggtt tttggctccg tcataataat tatcttctcc agcttcctcg
    69361 ataacgtttt ggactgccgt ctgatcaatc agttcatctt tatccatcac tttagcaaaa
    69421 tcctgactga cttccattac ttctggtaat ttaccggaac gagctaacgt aacgattttt
    69481 gtattgaacg ctgattcttc taccggcact tgcttgattt tgatgtctgg attttctttt
    69541 tcaaaatcag caaccagttc attgatcaca cttaatcgtt cctgttcgac agaagagtgc
    69601 atgaattgaa tcgttgtctg ttgtgattcg ttagagcttt gactttcacc acaagcagta
    69661 agaagaaatc cagtagctag cagacaggta gtaacaataa tttttttcat ttttttccac
    69721 ctcttatttt attattttca gccacatata ttcatacggc tggaatatca actttcgttc
    69781 ttgactgcaa tggataattt gtccagaaaa caggtctagg taatctcctt ttggtaaaag
    69841 ataacctgct gattgattgg aaaaattatg gataactaag actttctctt ccttcgcttc
    69901 gcgaataaaa ctgataaaag aatctgctga gtccagtaag taaatcaaac tattcggatg
    69961 gaaggctttt tctttttttc gaatagatag catctgggtc aattcaccat atactgctgt
    70021 tcttaatgga tctgtctgca actctttctc aatatctgct aacaaaaatt tttgccgatt
    70081 gatttttcga ttctctcctg ttttttctac gcctttgtaa tcatttcgac ttcccagcac
    70141 actttgaata taaattgccg gcacgcctgg taacgttacc aaaaatgaat gagcagctaa
    70201 aaagcgtttg cttctccatt ccgtcgtatc tgttggagaa cttaacgcat ctagatacgt
    70261 agcgtttatc tcatatggac tggtcgttcc atctgggttt ttcttgtagt ttactcgggc
    70321 accctctttc ttcagctgtt ccactaattc aaggatcgtt ttttccggca gaatacctcg
    70381 taccggattc aatccgatac cgtcatggga ggctaaaaaa ttaaaaaaag ttgttttttt
    70441 cgatgcgaaa tcgatggttt ttaaccattc tttcaactta cttgtattac ccgaacgaat
    70501 cgcttgaagg gtcaaaggtg gtagcgaaaa ctgatagacc atctgtgctt cattctcgcc
    70561 attcccaaaa taactgatat tatctttgtg tggcacattt gtctcagtga tcaataccgt
    70621 tcctggagct gcttcatcag cgattgcacg gaataattgg atgattttat gcgtttctgg
    70681 caggtgtata caagaagttc ctagttcttt ccataaaaat cccacagcgt ccaagcgaat
    70741 aaatgaagcg cctttttcta agtaaaacaa aagaatatcg atcattttca ataaaacttc
    70801 tggattttta aaattcaagt ctacttgatc ttcgctaaaa gtcgtccata cgtgtttttc
    70861 tttcccgttt ttgtcaatga acgttgtaag taacgggctg gtccttggtc tagtcacgct
    70921 gcttgtatct gtatccagtg gcaaatcaat aaaaaaatct ttgtacgtat cattcaagtt
    70981 taaatattcc tgaaaccaag tactttcggc agacatatga ttgcagacaa agtcgaacat
    71041 taaccgtgtt tcgcttctca tttcttctat atcttcccat gtgcccaaac ggtcgttgat
    71101 tgcctgataa tttacaacgg agaaaccatc atcagatgta tatgggaaaa atggcaagaa
    71161 atgtacaact ctaaatgtat ctgccaaata cttttgataa aatttcttaa atgtacgcaa
    71221 agttggttgc tgctcttcaa aaaattgatc cccataagta atcaagaaaa tatcttcttc
    71281 gtcccaatgc agtttgcctg cctggccttt cttctgctga taaacactga ctttttgttc
    71341 aatcatagag gcggttttct cagacaaatc tgagtcgcga taaatcgctt gtaaaagttt
    71401 tgtatacatc ggattcccct ttcttttttg ggagcgttcc caacgatttg atcatattat
    71461 ggaaaacgct tactgtcaat agcatttttt taaataattt tgatatacac aaaaatacaa
    71521 ataagaaagc ttatgtatca ataattaata gcttcttaaa aaaatatggt ctctcatgat
    71581 catgcaagct attcctaaat tttcaaaatc atagacaaaa aagaatgtct attgtactat
    71641 ggaattattc taaaacgctc ccaaaaagga ggtgcatata aaattgaaac ctactattta
    71701 tgacattgcg aaaaaagcta atgtctcaaa atcaactgtc tccagagtat taaataacca
    71761 gccaaatatc tctgataaag caaaagcaag tgtacttcaa gcaatcaaag aattgaatta
    71821 tgaaccgagc aaaattgcaa gaggactgtc aggaaatggt tttgacgcga ttctagcatt
    71881 atctcatcgt acttctcata cgacctatgg caatcctttt ttttcagatg ttattcaatc
    71941 catttctgcc gtttctgaac aaaataactt cgacttgatt ctacaaacgg caaaaacacc
    72001 agaagaagag ctagaaaaat gcgcgaaaaa gatccaagaa aaaatgatcc gaggaattat
    72061 tattttaagc tctacgatgg atgaaacact tctttttgaa ttggatcaat ataatattcc
    72121 tattgtggta atcggaaaag tcggaaacga ctacacgaac atctactcag tggacacgga
    72181 taatttccag gatagttacg atttggtgga aacactgatc aagaatggac accgtcatat
    72241 cggctgtctc catgctccga cagaagttta tgtatccaat gatcgtctca atggttaccg
    72301 tcaatgctta tttgatcacc acctagatat ccgtaatgaa tggattatag acggcggctt
    72361 tcgcttagaa gatagcatgg cagcaatgaa tgatttaatg aagctacgag aaagaccaac
    72421 tgcgattttt tctaccgatg cattaaaatc attgagtatt tacaaagtgg cagaacaatc
    72481 tggaaagcag atacctgatg atctttcgat cgcaggattc agtgatccct tattgtcctc
    72541 cctattttcg ccacagttga ctcggataga cattccgaca aatcagttag gaatcaaagc
    72601 cacagaactt ttattccaac taatccacca ccaataccct gaagaaaaaa gaatcattct
    72661 ttcaaccgag attactctca cagattcgat ccaacaacaa gaaatgtaga acagaattat
    72721 aaaagaacag aaacactgag gataagtcag ttactctgtt cttttttcaa tcactcatcc
    72781 ctcgttaccc cctcccggta ttttagcgaa tttttcttat tttccatctg ttttagatag
    72841 ctgtggataa ctataatgtt tgtgttaaac tattttttcc acagggaaga aaaaactatt
    72901 tttaaccacg ttgtgtataa gtttttatag ttcgtttttt taaacacatt tacccttatt
    72961 tcaatccatg ttatttgggg atacttatct ctaaaacata aatagaataa cagacatgtc
    73021 tactggtttt gttttattcg aggaattatt caataatagc tagcaaaata ttaaaaataa
    73081 ccgctctatc ttcccatcaa tttattttgc attcaaaaaa tgatctatct ttacttttgt
    73141 tgattgactt ctcttggaag atgatcgttc cgatacctta attggatacg aaccgatgtt
    73201 gttaagatcc tttcccactt ttcttctagt tagacaaatt attttagaca aaccaaaaaa
    73261 gaggttgtga caataatttg tcacaacctc ttttttaaaa tatctatttt gtttgattgt
    73321 tcattgcgtc ttctgcagcc atttgcgctt caatatctga aatactgtag acattttcgc
    73381 ttgctacacc gacttctttt ggttccatgt cacgataacg ttgcatacca gtaccagctg
    73441 ggatgatctt acctataata acattttctt tcaaaccaag aagaggatct ttcttaccgc
    73501 ggatcgcagc atccgtcaag acacgagttg tttcttggaa tgatgcagca gataagaaac
    73561 tatttgtttc taatgatgct tttgtgatac ctagtaagac aggtcgagaa gttgcaggaa
    73621 cgcctcctga gactagcgta ttgtagtttt gatctttaaa gtctgcgatg tctaataatg
    73681 tacctggtaa gatatctgta tcacctggat ccattacacg aactttacgc agcatttgac
    73741 gaaccattac ttcgatatgc ttgtcgccga tttctacccc ttgcatacgg taaacacgtt
    73801 gtacttcacg aagcaagtag ttttcaacag ataatacatc gcgaacttgc aacaattgtt
    73861 ttggatcgat tgatccttct gtcaatggtg caccacggtg gatcatatcg ccttctgcta
    73921 ctttcatacg tgctgtataa ggaacagtat acgtacgtgt atctgttttt cctttgattg
    73981 ttacttcttt ggtacgtgtt gcaggatctt ctgagatatc gatgacatcc cctgttactt
    74041 ctgtgatcac tgcttgccct ttcggattac gtgcttcaaa gatttcttgg acacgaggaa
    74101 gaccttgagt gatatcgtct ccggcaaccc cacctgtatg gaatgtacgc atcgtcaact
    74161 gagtaccagg ttcaccgatt gattgagcgg cgatcgtacc aactgcttct ccgacttcaa
    74221 cgtcagagcc agttgcaagg ttgcgtccgt aacaatgttt gcagacacca tgttttgtat
    74281 tacatgtgaa gacagaacgg attgtcactg tttcgacacc tgcatcaacg atttgttttg
    74341 cgatgtcttc ggaaatcaat tggtttcctg caatgatcaa ttcatttgtt tcaggatgac
    74401 gtacttcttt acgggtgtaa cgtcccacta aacgatcttc taatgattcg atgatttcat
    74461 ttccctcgcg gatggcttgg atttcaagac ctcggtcagt accgcaatct tcttcacgga
    74521 tgattacatc ttgggccacg tcaaccagac gacgagtcaa gtaacctgaa tcggcagtct
    74581 tcaaggctgt atcggtcatc cctttacgag ccccgtgagt tgagataaac atttccaaga
    74641 cggatagtcc ttcacggaag ttcgaaatga ttggcaattc catgattcga ccattaggag
    74701 cggccatcaa accacgcatt ccggcaagct gtgtaaagtt ggaaatgtta ccacgagctc
    74761 cagaatcaga catcatgaag attggatttt tcgcttccaa accttccatc agtttttgtt
    74821 ggatgctgtc ttttgcagca ttccaaacag caatgacacg ttcataacgt tcgtcatctg
    74881 tgatcagacc acgacggaat tgttttgtaa tagtttcaac ttgtttatgg gcattttcaa
    74941 tgatttcttg tttttcattc agtacactga tgtcagcgat ccctactgtg ataccggcat
    75001 gtgtcgaatg tttgtaccct aagtctttca tacggtcaag catcttagaa gtttctgtta
    75061 ctttgaatcg tttgaagact tctgcgatga tgtttcctaa gtttttcttc ttgaacggta
    75121 atactaattc ttgctctttg atatgtgcag gaatatcagt accagcttca acaaagtatt
    75181 tgtccggtgt ttggacggtc aagttgaagt ctgttggttc attcagataa gggaattcag
    75241 gaggcatgat ctcgttgaag atgatcttac caactgttgt gatcatcgta cgttcttttt
    75301 gccattcagt aaatggtttt tcacctaatg agttagggtt cacaccgata cgtgaatgta
    75361 aatgaacata tccgttgcgc catgcgataa cggcttcgtt ttgatctctg aagaccattc
    75421 cttcgccttc gcgtccttct tcttccattg tcaagtagta gttacctaga accatatctt
    75481 gagaaggagt aacaactggt ttaccatctt tagggttcaa gatgttttga gcagctaaca
    75541 tcaacatacg tgcttctgct tgtgcttctt cattcaatgg aacgtggaca gccatttggt
    75601 ctccatcgaa atcggcatta taagcttcac atacaagtgg atgcaaacgg attgcgcgtc
    75661 cttgtactaa aactggttcg aatgcttgga taccaagtcg gtgaagcgta ggtgcccggt
    75721 tcagcaatac tgggtgttcc ttgattacgt cttctaaaac atcccatact tcgtcttctt
    75781 gacgttcgat tttacgtttc gcatttttga tgtttgaagc tagttcgcgt tgaacaagct
    75841 cacgcatcac gaatggtttg aataattcaa tggccatttc ttttggaagt ccacattggt
    75901 acatcttcaa gaaaggtcca acaacgataa cggaacgacc tgagtagtcg acacgtttac
    75961 ctagcaagtt ttgacggaaa cgaccttgtt tccctttcaa catatgagaa agagatttca
    76021 atgggcggtt acctggtcca gtaactggac gtccgcgacg accgttatcg atcaatgcat
    76081 ctactgcttc ttgcagcata cgtttttcat tttgaacgat gattccaggt gcattcaagt
    76141 ctaacaaacg tttcaaacgg ttattacggt tgattacacg acggtaaaga tcattcaagt
    76201 cacttgttgc aaaacgtcca ccttctaatt gaaccattgg gcgtaaatct ggtggaataa
    76261 cagggataac gtccataacc atccagcttg gttgatttcc tgaagcgcgg aatgcttcta
    76321 aaatatccaa acggcggatt gcacgtgtac gtttttgtcc ttgtgcagat ttcaattctt
    76381 ctttcaattc ggctgcttct gcatctagat caacattatc aagtaattgt ttaatcgctt
    76441 ctgcacccat agcagcttgg aattcttgtc catattgttc acgtttttcg cgatattcgc
    76501 gttctgtcaa caattgtttt ttctctaaat tcgtatttcc tggttcgatg actacatatg
    76561 aagcaaaata aatgatttct tccaaagcgc gtgggctcat gtctaataca agacccatac
    76621 gtgaaggaat ccctttaaag taccagatat gtgaaacagg agctgctaat tcaatatgtc
    76681 ccatgcgttc acggcgaact ttcgaacgag taacttccac tccgcatcga tcacaaacga
    76741 ttcctttata acggatacgt ttgtattttc cgcaggcaca ttcccagtct tttgtaggac
    76801 caaaaatccg ctcacagaac aacccttcac gttcaggttt taaggtacga tagttaatcg
    76861 tctcaggttt ttttacttca ccgtaagacc agcttctgat tttttcggga gaagccaaac
    76921 ctatttgcat actttcgaat ttatttacat cgatcaaaag gggttccctc catttcattt
    76981 aatggcaaac cgcaagacgg ctgatcttcg accgccttgc agctcataga ccggattagt
    77041 ctaaattatc ttctgcggtt tcaaagtttt ggatgacatc gtctttttca tcttccactt
    77101 gttcagcagc tttcttttct aattctttgg cagtttgctg ttcggcaaat tttgtcaaag
    77161 catcaacagt gatcaaatcg tcgtcttcat cgtccatgtc gcgaagttcg atctctgttt
    77221 cttcgatatc caagacacgc atgtccagac ctagtgattg caattctttc accaatacgc
    77281 ggaatgattc cggtacacct ggttttggaa ttggttcacc cttgacgatt gcttcgtatg
    77341 ttttcacacg tccgactacg tcatctgatt tgtatgtcaa gatttcttgt aaagtataag
    77401 ccgcaccgta agcttccagt gcccatactt ccatttcacc aaaacgttgt ccaccaaatt
    77461 gagctttacc tcccaatggt tgttgtgtaa ccaatgagta aggtccgatt gaacgtgcat
    77521 gcaatttgtc atcgaccatg tgagcaagtt tgatcatgta catcacaccg acagacacac
    77581 gtccatcaaa tggttcacct gtacgtccgt cgtacagaac agttttcgca tcgctggcca
    77641 taccggcttc acgaactgtt tcccatacgt cttcatcact tgcaccatca aatactggcg
    77701 ttgctacgtg gatacctaac tgacgtgcag ccatacccaa gtgtaattcc aatacttgcc
    77761 cgatgttcat acgtgaaggc acccctaaag gattcagcat gatatcgatt ggtgttccat
    77821 caggtaggaa tggcatatct tcttccggca taatacggga tacaacccct ttatttccgt
    77881 gacgaccggc cattttatcc ccttcatgga ttttacgttt ttgaacgata taaacacgaa
    77941 ctaacatgtt tacgcctggt gacaattcat ctccagcttc acgagtaaag attttcacat
    78001 cgtgaacgat accgccgccg ccatgtggta cacgtaatga tgtatcgcgg acttcacgag
    78061 ctttttcgcc aaagatcgca tgcaatagac gttcttctgc agataattct gttacccctt
    78121 ttggcgtgac tttccctaca agcaaatcgc catcttggac ttctgcacca atacggatga
    78181 tacccatttc gtctaaatct tttaatgcgt cttccccgac attagggatt tcgcgtgtga
    78241 tttcttcagg tcctaatttt gtatcgcggg cttctgattc atattcttca atatggatag
    78301 aagtgtatac gtcatctttt accaaacgac ggctcatgat gatcgcatct tcatagttgt
    78361 acccttccca agtcatgaaa ccaactaaaa cgttttggcc tagagccatt tcgccttgtt
    78421 ccatagatgg tccgtctgcc agagtatccc ctttttcgac tttctcaccc aaatgaacga
    78481 ttggacgttg gttgtagctt gttccggagt ttgaacgacg gaattttgtt acatcgtatt
    78541 tatctaatgc accgttgtcg cggcgtacgc ggatttcaga agcatcaacg tattcaacga
    78601 caccgtcatg tttacataac aaagcagctc ctgagtcatg cgctgatttg tattccatac
    78661 cagtaccaac ccatggtgct tgaggattga tcaacggcac tgcttgacgc tgcatgttgg
    78721 cacccatcaa ggcacggttg gagtcatcgt tttccaagaa aggaatacat gctgtcgcaa
    78781 cggcaactac ttgtttaggt gatacgtcca tgtagtctac tttatcaata gatacttcta
    78841 agttttcact ttgagcacga gccataacaa cgtcttgagc aaatgttcca tcttcattca
    78901 atgggctgtt tgcttgggct acgatgtaat ggtcttcgat atcagctgtc aagtagtcga
    78961 tttggtcagt aacacgacct gtttcacggt ctacacgacg ataaggtgtt tcgataaatc
    79021 cgaatttatt tactttcgca taactggaca aactattgat caacccgatg tttgggcctt
    79081 caggagtttc gatcggacac atacggccat agtgggagta gtgaacgtca cgaacttcat
    79141 aaccggcgcg gtcacgagtc aatccgccag gtcctaaggc tgaaagacga cgtttgtgtg
    79201 tcaattcgcc aagagggttt gtttgatcca tgaactgtga caactgagaa gaaccaaaga
    79261 attctttgat acttgccaca actggacgga tattgatcaa ttgttgaggt gtcaatgttt
    79321 cagtatcttg gatcgacatt ctttcacgaa ccacacgttc catacgtgct agcccgatac
    79381 ggaattggtt ttgtaaaagt tcaccgactg aacggatacg acgatttcct aagtggtcga
    79441 tatcatcgac attgccgata ccttccatca agttcaagaa atagctcatt gaagcaatga
    79501 tgtcggctgg acgaaccgtt tttacagctg cttctggata gccgtttccg atcacgttta
    79561 cttcacgttc agggtctctt ggtgaaaata ctttgatgac ttggacagtc attggatctg
    79621 tgaccacacc gtcttctgat ggatagtaag tcactgaatt taggccatta tcaatgaaag
    79681 gagctagtgt ttccatgact tggtgagtca gaactgttcc tttttcaacg atgatctcgc
    79741 ctgtttctgg atcaactaat gtttcagcta atgtcagatt caatagacgt gttttcaaat
    79801 ctaatttttt gtttactttg taacgaccaa cgtttgctaa gtcgtaacgt tttggatcga
    79861 agaaacgagc attcagcaag ttacgtgagc tgtctgctgt ttttggttcg cctggacgca
    79921 aacgttcgta aacgtctttc aaaccttctt ctgttcttga gtcgcttgcg tttttatgca
    79981 agtctttttc gactgtattg cgtaatgttt cgctgtcgcc gaagatttca aagatcgtat
    80041 catcggaacc aaatcctaac gcacgaacta atacggttaa aggaatctta cgtgtacggt
    80101 cgatacgtac ataagagatg tcttttgcat cagtttccat ttctagccaa gctccacggt
    80161 tagggataac agtagaaccg aatccttctt ttccgttttt gtcgactttt ccatggaaat
    80221 agacacctgg tgaacggact aactgagaaa cgattactcg ctctgccccg ttgatgatga
    80281 atgttccttg ttctgtcatt aatgggaaat caccgaagaa tacttcttgt gctttgattt
    80341 cgccagtctc gcggtttgtc aaacgcaatg ttacatgtaa tggtgcagag tagtttgcat
    80401 catgcgcacg agcttctgct actgtatact ttggttcttt caattcataa tctacaaatt
    80461 ccaaagatag attgccattg aagtcatcga ttggcaaaat gtcttcaaac atttctctaa
    80521 gtccctcatc taagaaccat tggtaagagt ctgtttgaat ttcgatcaaa tttggtaatt
    80581 ccaacacttc actgattctt gcgaaacttc tacgttcgcg atgttttccg tattttacta
    80641 cgtgtccagc caagctcttc acccctctaa aatgtcattc aaaaagacta cccgatcaat
    80701 tgttacaata atatttcaaa tattattttt aggtaacaac agacattttt tgcggctttt
    80761 aggcaaaaaa aaaccaaaaa tagaacattc tcttgaaacc ttacttcgtg agcttctact
    80821 tttgtttcct tatattaaag ccgaaacgga caatatttcg tttctgcctt ttcttcatca
    80881 gatagttttt gcaacttcat atactacact tattttctat aaaagtcaac acttcctggc
    80941 gtttcttctg ctttttcgca acattttctt aatgttttca attttatgtt ttcaattatc
    81001 tgacaattct taattgacag acctttttat ctcggttata ctttagaaaa ttcattttgt
    81061 ggaggaactt ctatgcgaac caacatcaac caaatcgcac caacacaact gaataacttt
    81121 tactttagct actttagata ggtttgtatt catcatgatg gatacaaacg ttaaacgaca
    81181 gtttgtatct atgatggcta aagaactttg tattgcagca aaaagccacg tagacaaaat
    81241 gctaagtggc tgagcagtga aaatacaaag taaaagtatc aagcattcta ctttttcaat
    81301 ttattttccg acttttcaat ccatttggac attttgtctg aatggatttt ttgtttccca
    81361 aaattaagga ggaaaaagaa atgaaaaaaa atataatcat cggattaggc gctgccctgc
    81421 tactagcttt aggaggttgc gcacaaaaag acaattccgc agaggcatca gatggacaaa
    81481 aaacaattgg cgtattgcaa cttgtacaac ataactcgtt agatgctgcc tataaaggat
    81541 tcaaagaagg attagcagaa gaagggtata aagaaggcga taatctaaca atcgattatc
    81601 aaaatgccca aaacaatcaa gacaacctga aaagtatgag tgagaaactc gtcaaagaag
    81661 atcctgattt gctacttgga atcgccactc cagcagcaca atctttatta aatgaaacaa
    81721 ccactatccc gatgactgtc acagcggtca cagacttgga acaagcccat ttagtcacat
    81781 ccaatgaaaa acctggcggc aatgtgactg gcacgacaga tatggtgcca atcgaaaaac
    81841 aaatcggctt actgttaaat atcgtgccag acgccaaaac aatcggcatc atgtataaca
    81901 acggtgaagc aaactctaag atccaagctg atttggcaga aaaagaattg aaaaaagcgg
    81961 gcgtcaaagt caaagtactg acagcaaatt ccacaaatga tgtccaacaa gtgacgaaaa
    82021 gtctagctaa agatgtagat ggaatctata ttcctactga taacacgttc gcaagtgcgg
    82081 caagtgttgt cggtgaagtc gcaaaagaaa caaaaacacc tgtcgttgct ggcgcagttg
    82141 atcaagtcaa agacggcggt ctagcaacag taggaatcga ctacgaaagc ttgggcaaac
    82201 aaacagggat catggcagca aaaatcttag acggcaagaa tccaagtgaa cttcctgtcg
    82261 aaacagcgaa tgatttggaa ctgtatgtca ataaagacat ggccaaagca ttaggcatca
    82321 atccagacag catcaaagaa gctgaataaa acacaggagg attctcatga caaatttgct
    82381 ctctcttttc ttatcatctg catcgcaagg ggtcttatgg gccctacttg cgattggtgt
    82441 atacgtcact ttccgtatct tggacattgc cgacttgact gctgaaggaa gctttccttt
    82501 aggtgcaggg atcgcggcag taagtattac aaatggctat catccattga cagcttgtct
    82561 tctaggcttt ttagggggtg cggcagcagg gcttgtttcc ggactgcttc acacaaaatt
    82621 gaaaattccc gcccttcttg cagggatcat caccatgact ggtttatatt ctgtcacatc
    82681 ccgtgtgatg ggtgcgccga acatctcttt attgggtcag ccaacgatct ttcattgggt
    82741 cgagtcattc ggcataacaa aagacaacgc tgtactgatc gtcggtctgc tttttgcttt
    82801 gatcgttgta tgtttacttg ttttgttctt acgtacagaa acaggacttg ctattcgtgc
    82861 aactggcgat aatctggcaa tgagcgaagc aaacgggatc aacacagata atatgaagat
    82921 catcggttat atgatttcta atggatgcat tgctctttct ggctccttac ttgcgcaaaa
    82981 caacggcttt gctgatttaa attctggtat tggaacgatc gtaattggac ttgcttctat
    83041 tatcatcgca gaagttttgt tacgtaacca gccactattt ctccgtctct tgactgtcgt
    83101 tttaggtgcg gtcatttatc gttttatttt agcgttagtc ttcgaactga atgttgaacc
    83161 aagtgattcg aaacttgctt ctgctttcgt gctagtgatc tgtctttctt tcccgcagat
    83221 ccagcaaaaa ttccatttac ctcaaaaaaa gaaaggcggt agtgtcaaat gaatgacgtc
    83281 ttaacattgg aaaatctcca tcataccttt gaaaaaggaa cgatcaacga aaatcatgtc
    83341 ctgaaaggca ttaatctttc cttagatccc ggcgacttcg tgacgatcat cggtggaaat
    83401 ggggctggta aatctacttt gctgaacagc atcgccggta cattttctgt cgatcagggt
    83461 caaattttat tgaatggaaa aaatatcacg aaaaaatctg ttgtcgaacg ttcgaaatcc
    83521 atcagtcgcg tattccaaga tcctaaacta gggacagccg ttcgtttaac ggtagaagaa
    83581 aatcttgctc ttgctatgaa acgaggaaaa aaacgcggct tcttccgtgg tgtcaaacca
    83641 caagaccgaa catttttcaa agaccagctg gttcggctaa atttggggtt ggaaaatcgt
    83701 ttatcctcag aaatcggttt gctgtctgga ggacaacgtc aagctattac gttattgatg
    83761 gccacattac agcgtccaga actgatctta ttagatgaac acactgcagc gcttgaccct
    83821 gctacttcca aaacggtgat ggaattgaca gaaaagctga tcactgagca gaatctcact
    83881 gcttttatgg tcactcatga catggaagac gcgatccgct atgggagtcg actgatcatg
    83941 ctgcatcaag gaaggatcgt cgtagatatc cagcaagagg aaaaacagca gctcacagtg
    84001 ccccaattat tagcgttgtt caaacaaaac agcggcacgg cattaaaaga cgatcaagta
    84061 cttttatctt cataatcaga aagaggatgg gacaaaaaat gaacgcccac cctcttcttt
    84121 tttctctttc cttctttcgt ttttgcttta tgtatcaacc gttgtttctt cgaaaactat
    84181 tttgttctct ccttcttcct gatagaatgg atgggaaagg agcttgatgc catgacaacg
    84241 aaagacaagg tacttcaatt attgaaaaag acaccagatt ttctttccgg agaaaagttg
    84301 gcacagcaac tggaagtttc ccggacaagt atttggaaag ccatcaaaga attggaaaag
    84361 gcaggctatc gttttgagca cgggcctaca gggtatcgtt acctgccctc tgacgtacta
    84421 gatgcaaaag aaatccagca agagctacgg tcgtttattc ctgatttgaa agtacaaacg
    84481 atgttgactt ctgaatctac gatgaaagat gccaaactgg cagcagctca aggagattct
    84541 gtttcgaagt tatttgttgc tgatacacaa gaacaagctc gtggacgttt tggacggcct
    84601 tttttcgctg aacctggacg aggaatctac atgagtctct tgctccatcc agacaaacgg
    84661 tttgatgaat tgcctcaata tacgatcatc gcagccagtg cctgtgtgaa agccattgaa
    84721 tctgtaaccg gtcgttctgc ttcgatcaaa tgggtcaatg atatctacat ggatggaaaa
    84781 aaagtctgtg ggattttatc tgaagcagtc agtgatatgg aaagcggcag gatcagtcat
    84841 atcatcattg ggatcgggct taatttttct gttcctcaaa atcattttcc agctgatctc
    84901 caagaaaaag ccatctctgt ctttcccgac ggacaagcta gtgtcacaag gaatcagcta
    84961 atcagcaaaa tctggcaaga attgttcact tatctttctc acccagaaaa agcgttggac
    85021 ttctataaag aaaaatcatt cgtattggga aaaaccgtgt cgttcaatca aaaaggaacg
    85081 acttatgtcg gtcttgcaaa agaaatcggt gatcatggcg aactgatcgt ccaaacaaat
    85141 gaacagaaga tgagtttgtc ttctggcgaa atcagtctca catctatccg tacgcaataa
    85201 ttatcagatt tcacaaaagg acacctgatc tcatacagtg tccttttttc tgaattctct
    85261 tcaaaagact ctccttattc tatcagctga cagtttctct atcctctaga aaaaggtatt
    85321 ctaaaaatat ctataaagca tggtacactt tctttaaatg aatcaatgca aaaaacaaga
    85381 gagtcatcag tttacacgat caaaagagat agcaggccgc ttcctttttc aatcttatag
    85441 atagaccatg ggtaacgata aaaacaaaaa agaacttgcg acttattttg ccgtaagttc
    85501 ttttttagct agtgccttaa tctcttaatc ccaacaaacg tctcgcatag atcacctgac
    85561 cagagtgcat agcagcatca tcaataatag aaacgagacg cattcctcgt gtgactggtg
    85621 gtgtccagtt ctcgtcaatt acttcatcta gctcggaagg ttccagcctt cttaagtaag
    85681 aaatagcaaa atcagcagct cctcgcaagt atcctagcag atcttctatt tgattagctt
    85741 ggatctgctt tgcttgttcc agactatgct tccaatcttg ttcgttatct gctatcgtca
    85801 tcggaaaccg gctttcccag tcttgactat gccaaattgg agaagttcct gctaaatcag
    85861 caatctggaa atctaattct cgagcggtat gccaagccag ccaagtcatt gatttgatct
    85921 gcggggctct atcttccact ggaaaacgat tggcctcctc aatagagacg ccttcaaaca
    85981 aacgttcaaa ccgatcgtat gcccgatcca cactctcgca tagcatatct aaataatcca
    86041 tttattttcc tcctttttat ttatcctact tactttttcc taattctagg atacctactt
    86101 atatgttact acacaccctt attttttaca ctttaacagt caccatcatc aatagtttgg
    86161 agattgaaag aaaaagatag tgtcgaacta tcaattgaac aagaagcaac aatatgaacg
    86221 tttcattaat attctttaaa taaacaatga tttttcaaac gaacagttta agactaggag
    86281 aaaaagagta taataggaaa atgtttgaaa ggaaaggaag gggaaaaatg aaaaaaaggg
    86341 caagtttact agtcctagtt gctttgttgt tcaatatctt ttcgtatggt gtggccgttt
    86401 cagcggaaac atacattcct aaagaccctg ggaatattta taatgatcta actggtaact
    86461 atggcttgtt aggaattgct agtcaattcc acgtatttgc taaaaataag acaactgtga
    86521 atgcacatac agacggaaat atagcaacac atgaacttga tgcaaaaaat aattttggta
    86581 cagagcttca tgaaggttta ttgaaccaag aaataaatta tatacaaaaa actgattctt
    86641 tcgctaattc ttcaggcata cctacaggta gcacaagaat gaataaattt gtcgttggca
    86701 gtaacgtgga tgtagcactt caagatggtc atcctacagt caatggatcc aggcttgatc
    86761 acttaactcc agatgatttt tataaagatc gtgctgggca tgaatatatt gatttcgagc
    86821 aggaatttgc taaattgaat gtagcagcaa atgatcttgc aacgatcact ccagctaaaa
    86881 catatactgc tgcagatttt ccagacatga acaatcggac aatcgattta actgatttat
    86941 cagataccgg gtttttattg gtaaatatcg atgcagaagt gttaacgatg aatacgccac
    87001 ttcaaatcat taatccaaat gatcaagtag ttgtatttaa tgtcatcaac agttcttctg
    87061 cattgaacgt acagtcacca atcaaataca atgatcgttc aaatcatgaa acagaagatt
    87121 tttcggatgc gaatatctct tggaattttg gaaatgagat gactgatttg acaatcagtg
    87181 ctccttttca aggaacaatc cttgcgccta atgctactat ccgcattact caaaaccaag
    87241 acggaacgat tataggaaca aatgtgattt tagatgcagc taccaatcgt tgggatccta
    87301 acgaaatatt tatcagcgac aatggtacag atacgacaga cacaagcgac agtacagata
    87361 catctaccac aagtgatagc tcagattcat ca
//
LOCUS       DAYNVV010000004        77109 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.004, whole genome shotgun sequence.
ACCESSION   DAYNVV010000004 DAYNVV010000000
VERSION     DAYNVV010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 77109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77109
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.004"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            182..1309
                     /locus_tag="ACGXWR_000388"
                     /pseudo
     CDS             182..1309
                     /locus_tag="ACGXWR_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetM/TetW/TetO/TetS family tetracycline
                     resistance ribosomal protection protein"
     gene            1407..1595
                     /locus_tag="ACGXWR_000389"
     CDS             1407..1595
                     /locus_tag="ACGXWR_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HFK0802006.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(1653..2006)
                     /locus_tag="ACGXWR_000390"
     CDS             complement(1653..2006)
                     /locus_tag="ACGXWR_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0802007.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            2537..2959
                     /locus_tag="ACGXWR_000391"
     CDS             2537..2959
                     /locus_tag="ACGXWR_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFK0802008.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            2956..3186
                     /locus_tag="ACGXWR_000392"
     CDS             2956..3186
                     /locus_tag="ACGXWR_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0802009.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            3684..3884
                     /locus_tag="ACGXWR_000393"
     CDS             3684..3884
                     /locus_tag="ACGXWR_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HFK0802010.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            3911..5104
                     /locus_tag="ACGXWR_000394"
     CDS             3911..5104
                     /locus_tag="ACGXWR_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFK0802011.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(5172..6737)
                     /gene="guaA"
                     /locus_tag="ACGXWR_000395"
     CDS             complement(5172..6737)
                     /gene="guaA"
                     /locus_tag="ACGXWR_000395"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFK0802012.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(6796..7719)
                     /gene="coaA"
                     /locus_tag="ACGXWR_000396"
     CDS             complement(6796..7719)
                     /gene="coaA"
                     /locus_tag="ACGXWR_000396"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HFK0802013.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            7915..8520
                     /locus_tag="ACGXWR_000397"
     CDS             7915..8520
                     /locus_tag="ACGXWR_000397"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFK0802014.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            8828..9844
                     /locus_tag="ACGXWR_000398"
     CDS             8828..9844
                     /locus_tag="ACGXWR_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFK0802015.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            9985..11286
                     /locus_tag="ACGXWR_000399"
     CDS             9985..11286
                     /locus_tag="ACGXWR_000399"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HFK0802016.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            11332..11994
                     /gene="deoC"
                     /locus_tag="ACGXWR_000400"
     CDS             11332..11994
                     /gene="deoC"
                     /locus_tag="ACGXWR_000400"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HFK0802017.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            12015..12413
                     /locus_tag="ACGXWR_000401"
     CDS             12015..12413
                     /locus_tag="ACGXWR_000401"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HFK0802018.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            12479..13561
                     /locus_tag="ACGXWR_000402"
     CDS             12479..13561
                     /locus_tag="ACGXWR_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFK0802019.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            13773..15335
                     /locus_tag="ACGXWR_000403"
     CDS             13773..15335
                     /locus_tag="ACGXWR_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802020.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            15328..16461
                     /locus_tag="ACGXWR_000404"
     CDS             15328..16461
                     /locus_tag="ACGXWR_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0802021.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            16461..17417
                     /locus_tag="ACGXWR_000405"
     CDS             16461..17417
                     /locus_tag="ACGXWR_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0802022.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            17516..18682
                     /gene="deoB"
                     /locus_tag="ACGXWR_000406"
     CDS             17516..18682
                     /gene="deoB"
                     /locus_tag="ACGXWR_000406"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HFK0802023.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            18706..19524
                     /locus_tag="ACGXWR_000407"
     CDS             18706..19524
                     /locus_tag="ACGXWR_000407"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFK0802024.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            19541..20248
                     /gene="deoD"
                     /locus_tag="ACGXWR_000408"
     CDS             19541..20248
                     /gene="deoD"
                     /locus_tag="ACGXWR_000408"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFK0802025.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(20546..21232)
                     /gene="gpmA"
                     /locus_tag="ACGXWR_000409"
     CDS             complement(20546..21232)
                     /gene="gpmA"
                     /locus_tag="ACGXWR_000409"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFK0802026.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(21404..21985)
                     /locus_tag="ACGXWR_000410"
     CDS             complement(21404..21985)
                     /locus_tag="ACGXWR_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFK0802027.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(22118..22801)
                     /gene="rpiA"
                     /locus_tag="ACGXWR_000411"
     CDS             complement(22118..22801)
                     /gene="rpiA"
                     /locus_tag="ACGXWR_000411"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HFK0802028.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            23120..23533
                     /gene="rpsL"
                     /locus_tag="ACGXWR_000412"
     CDS             23120..23533
                     /gene="rpsL"
                     /locus_tag="ACGXWR_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HFK0802029.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            23617..24087
                     /gene="rpsG"
                     /locus_tag="ACGXWR_000413"
     CDS             23617..24087
                     /gene="rpsG"
                     /locus_tag="ACGXWR_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HFK0802030.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            24181..26268
                     /gene="fusA"
                     /locus_tag="ACGXWR_000414"
     CDS             24181..26268
                     /gene="fusA"
                     /locus_tag="ACGXWR_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFK0802031.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            26440..27627
                     /gene="tuf"
                     /locus_tag="ACGXWR_000415"
     CDS             26440..27627
                     /gene="tuf"
                     /locus_tag="ACGXWR_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFK0802032.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            28034..28342
                     /gene="rpsJ"
                     /locus_tag="ACGXWR_000416"
     CDS             28034..28342
                     /gene="rpsJ"
                     /locus_tag="ACGXWR_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HFK0802033.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            28373..29002
                     /gene="rplC"
                     /locus_tag="ACGXWR_000417"
     CDS             28373..29002
                     /gene="rplC"
                     /locus_tag="ACGXWR_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HFK0802034.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            29030..29653
                     /gene="rplD"
                     /locus_tag="ACGXWR_000418"
     CDS             29030..29653
                     /gene="rplD"
                     /locus_tag="ACGXWR_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HFK0802035.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            29653..29943
                     /gene="rplW"
                     /locus_tag="ACGXWR_000419"
     CDS             29653..29943
                     /gene="rplW"
                     /locus_tag="ACGXWR_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HFK0802036.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            29982..30815
                     /gene="rplB"
                     /locus_tag="ACGXWR_000420"
     CDS             29982..30815
                     /gene="rplB"
                     /locus_tag="ACGXWR_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HFK0802037.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            30858..31136
                     /gene="rpsS"
                     /locus_tag="ACGXWR_000421"
     CDS             30858..31136
                     /gene="rpsS"
                     /locus_tag="ACGXWR_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HFK0802038.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            31159..31506
                     /gene="rplV"
                     /locus_tag="ACGXWR_000422"
     CDS             31159..31506
                     /gene="rplV"
                     /locus_tag="ACGXWR_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HFK0802039.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            31520..32176
                     /gene="rpsC"
                     /locus_tag="ACGXWR_000423"
     CDS             31520..32176
                     /gene="rpsC"
                     /locus_tag="ACGXWR_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HFK0802040.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            32179..32613
                     /gene="rplP"
                     /locus_tag="ACGXWR_000424"
     CDS             32179..32613
                     /gene="rplP"
                     /locus_tag="ACGXWR_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011375443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HFK0802041.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            32603..32791
                     /gene="rpmC"
                     /locus_tag="ACGXWR_000425"
     CDS             32603..32791
                     /gene="rpmC"
                     /locus_tag="ACGXWR_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HFK0802042.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            32816..33082
                     /gene="rpsQ"
                     /locus_tag="ACGXWR_000426"
     CDS             32816..33082
                     /gene="rpsQ"
                     /locus_tag="ACGXWR_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HFK0802043.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            33140..33508
                     /gene="rplN"
                     /locus_tag="ACGXWR_000427"
     CDS             33140..33508
                     /gene="rplN"
                     /locus_tag="ACGXWR_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HFK0802044.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            33545..33853
                     /gene="rplX"
                     /locus_tag="ACGXWR_000428"
     CDS             33545..33853
                     /gene="rplX"
                     /locus_tag="ACGXWR_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HFK0802045.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            33881..34420
                     /gene="rplE"
                     /locus_tag="ACGXWR_000429"
     CDS             33881..34420
                     /gene="rplE"
                     /locus_tag="ACGXWR_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HFK0802046.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            34439..34624
                     /locus_tag="ACGXWR_000430"
     CDS             34439..34624
                     /locus_tag="ACGXWR_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HFK0802047.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            34660..35058
                     /gene="rpsH"
                     /locus_tag="ACGXWR_000431"
     CDS             34660..35058
                     /gene="rpsH"
                     /locus_tag="ACGXWR_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HFK0802048.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            35090..35626
                     /gene="rplF"
                     /locus_tag="ACGXWR_000432"
     CDS             35090..35626
                     /gene="rplF"
                     /locus_tag="ACGXWR_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HFK0802049.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            35787..36143
                     /gene="rplR"
                     /locus_tag="ACGXWR_000433"
     CDS             35787..36143
                     /gene="rplR"
                     /locus_tag="ACGXWR_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HFK0802050.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            36164..36664
                     /gene="rpsE"
                     /locus_tag="ACGXWR_000434"
     CDS             36164..36664
                     /gene="rpsE"
                     /locus_tag="ACGXWR_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HFK0802051.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            36679..36858
                     /gene="rpmD"
                     /locus_tag="ACGXWR_000435"
     CDS             36679..36858
                     /gene="rpmD"
                     /locus_tag="ACGXWR_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HFK0802052.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            36902..37342
                     /gene="rplO"
                     /locus_tag="ACGXWR_000436"
     CDS             36902..37342
                     /gene="rplO"
                     /locus_tag="ACGXWR_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HFK0802053.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            37342..38637
                     /gene="secY"
                     /locus_tag="ACGXWR_000437"
     CDS             37342..38637
                     /gene="secY"
                     /locus_tag="ACGXWR_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HFK0802054.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            38699..39346
                     /locus_tag="ACGXWR_000438"
     CDS             38699..39346
                     /locus_tag="ACGXWR_000438"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HFK0802055.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            39537..39755
                     /gene="infA"
                     /locus_tag="ACGXWR_000439"
     CDS             39537..39755
                     /gene="infA"
                     /locus_tag="ACGXWR_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HFK0802056.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            39788..39904
                     /gene="rpmJ"
                     /locus_tag="ACGXWR_000440"
     CDS             39788..39904
                     /gene="rpmJ"
                     /locus_tag="ACGXWR_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HFK0802057.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            39922..40287
                     /gene="rpsM"
                     /locus_tag="ACGXWR_000441"
     CDS             39922..40287
                     /gene="rpsM"
                     /locus_tag="ACGXWR_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HFK0802058.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            40315..40704
                     /gene="rpsK"
                     /locus_tag="ACGXWR_000442"
     CDS             40315..40704
                     /gene="rpsK"
                     /locus_tag="ACGXWR_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HFK0802059.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            40784..41722
                     /locus_tag="ACGXWR_000443"
     CDS             40784..41722
                     /locus_tag="ACGXWR_000443"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HFK0802060.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            41750..42130
                     /gene="rplQ"
                     /locus_tag="ACGXWR_000444"
     CDS             41750..42130
                     /gene="rplQ"
                     /locus_tag="ACGXWR_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HFK0802061.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            42402..43241
                     /locus_tag="ACGXWR_000445"
     CDS             42402..43241
                     /locus_tag="ACGXWR_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFK0802062.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMIFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            43217..44086
                     /locus_tag="ACGXWR_000446"
     CDS             43217..44086
                     /locus_tag="ACGXWR_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFK0802063.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            44076..44873
                     /locus_tag="ACGXWR_000447"
     CDS             44076..44873
                     /locus_tag="ACGXWR_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFK0802064.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            45076..45822
                     /gene="truA"
                     /locus_tag="ACGXWR_000448"
     CDS             45076..45822
                     /gene="truA"
                     /locus_tag="ACGXWR_000448"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFK0802065.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(46155..48824)
                     /locus_tag="ACGXWR_000449"
     CDS             complement(46155..48824)
                     /locus_tag="ACGXWR_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFK0802066.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDGGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(49062..49250)
                     /gene="rpmB"
                     /locus_tag="ACGXWR_000450"
     CDS             complement(49062..49250)
                     /gene="rpmB"
                     /locus_tag="ACGXWR_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HFK0802067.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            49520..49882
                     /locus_tag="ACGXWR_000451"
     CDS             49520..49882
                     /locus_tag="ACGXWR_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFK0802068.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            49934..51616
                     /locus_tag="ACGXWR_000452"
     CDS             49934..51616
                     /locus_tag="ACGXWR_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HFK0802069.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            51733..53769
                     /gene="recG"
                     /locus_tag="ACGXWR_000453"
     CDS             51733..53769
                     /gene="recG"
                     /locus_tag="ACGXWR_000453"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HFK0802070.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            53818..54819
                     /gene="plsX"
                     /locus_tag="ACGXWR_000454"
     CDS             53818..54819
                     /gene="plsX"
                     /locus_tag="ACGXWR_000454"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HFK0802071.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            54941..55183
                     /gene="acpP"
                     /locus_tag="ACGXWR_000455"
     CDS             54941..55183
                     /gene="acpP"
                     /locus_tag="ACGXWR_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFK0802072.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            55451..56455
                     /locus_tag="ACGXWR_000456"
     CDS             55451..56455
                     /locus_tag="ACGXWR_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802073.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            56456..57400
                     /locus_tag="ACGXWR_000457"
     CDS             56456..57400
                     /locus_tag="ACGXWR_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802074.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            57400..58362
                     /gene="opp4B"
                     /locus_tag="ACGXWR_000458"
     CDS             57400..58362
                     /gene="opp4B"
                     /locus_tag="ACGXWR_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFK0802075.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            58389..59303
                     /locus_tag="ACGXWR_000459"
     CDS             58389..59303
                     /locus_tag="ACGXWR_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0802076.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            59329..61110
                     /locus_tag="ACGXWR_000460"
     CDS             59329..61110
                     /locus_tag="ACGXWR_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFK0802077.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            61458..62144
                     /gene="rnc"
                     /locus_tag="ACGXWR_000461"
     CDS             61458..62144
                     /gene="rnc"
                     /locus_tag="ACGXWR_000461"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HFK0802078.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            62164..65745
                     /gene="smc"
                     /locus_tag="ACGXWR_000462"
     CDS             62164..65745
                     /gene="smc"
                     /locus_tag="ACGXWR_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HFK0802079.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            65754..66563
                     /locus_tag="ACGXWR_000463"
     CDS             65754..66563
                     /locus_tag="ACGXWR_000463"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFK0802080.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            66574..67572
                     /gene="ftsY"
                     /locus_tag="ACGXWR_000464"
     CDS             66574..67572
                     /gene="ftsY"
                     /locus_tag="ACGXWR_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HFK0802081.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            67759..70026
                     /gene="gshAB"
                     /locus_tag="ACGXWR_000465"
     CDS             67759..70026
                     /gene="gshAB"
                     /locus_tag="ACGXWR_000465"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HFK0802082.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(70115..70567)
                     /locus_tag="ACGXWR_000466"
     CDS             complement(70115..70567)
                     /locus_tag="ACGXWR_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HFK0802083.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            70717..71667
                     /locus_tag="ACGXWR_000467"
     CDS             70717..71667
                     /locus_tag="ACGXWR_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFK0802084.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            71660..72619
                     /locus_tag="ACGXWR_000468"
     CDS             71660..72619
                     /locus_tag="ACGXWR_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFK0802085.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            72616..73371
                     /locus_tag="ACGXWR_000469"
     CDS             72616..73371
                     /locus_tag="ACGXWR_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802086.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            73394..74347
                     /locus_tag="ACGXWR_000470"
     CDS             73394..74347
                     /locus_tag="ACGXWR_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HFK0802087.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(74991..75287)
                     /locus_tag="ACGXWR_000471"
     CDS             complement(74991..75287)
                     /locus_tag="ACGXWR_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HFK0802088.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            75642..75998
                     /locus_tag="ACGXWR_000472"
     CDS             75642..75998
                     /locus_tag="ACGXWR_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFK0802089.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            76008..76907
                     /locus_tag="ACGXWR_000473"
     CDS             76008..76907
                     /locus_tag="ACGXWR_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFK0802090.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
BASE COUNT        25140 a        13913 c        16508 g        21548 t
ORIGIN      
        1 aattttttct ataagttata ttatcataat accacaaaat cacaaatttt cattcaatta
       61 tcattttcaa ttgcatttta taaatcattt tgtatgtaat ttggtatgta agttaaaatg
      121 aaaaaagtag tccattttga agtacatttt gtcattttgt actccaaaac tgaactactt
      181 acttgcatat atacgccttt atagtggagt actacattta cgagattcgg ttagagtatc
      241 agaaaaagaa aaaataaaag ttacagaaat gtatacttca ataaatggtg aattatgtaa
      301 gattgataga gcttattctg gagaaattgt tattttgcaa aatgagtttt tgaagttaaa
      361 tagtgttctt ggagatacaa aactattgcc acagagaaaa aagattgaaa atccgcaccc
      421 tctactacaa acaactgttg aaccgagtaa acctgaacag agagaaatgt tgcttgatgc
      481 ccttttggaa atctcagata gtgatccgct tctacgatat tacgtggatt ctacgacaca
      541 tgaaattata ctttctttct tagggaaagt acaaatggaa gtgattagtg cactgttgca
      601 agaaaagtat catgtggaga tagaactaaa agagcctaca gtcatttata tggagagacc
      661 gttaaaaaat gcagaatata ccattcacat cgaagtgccg ccaaatcctt tctgggcttc
      721 cattggttta tctgtatcac cgcttccgtt gggaagtgga atgcagtatg agagctcggt
      781 ttctcttgga tacttaaatc aatcatttca aaatgcagtt atggaaggga tacgctatgg
      841 ttgcgaacaa ggattatatg gttggaatgt gacggattgt aaaatctgtt ttaagtacgg
      901 tttatactat agccctgtta gtactccagc agattttcgg atgcttactc ctattgtact
      961 ggagcaagcc tttagaaaag ctggaacaga attgttagag ccatatctta gttttaaagt
     1021 ttatgcacca caggaatatc tttcacgggc atataacgat gctcccaaat attgtgcaaa
     1081 tatcgtaaat actcaactga aaaataatga ggtcattatt attggagaaa ttcctgctcg
     1141 atgtattcaa gattatcgca atgatttaac tttttttaca aatgggctta gtgtttgttt
     1201 agcagagcta aaaggatatc aggttaccac tggcgaacct gtttgccaga cccgtcgtct
     1261 aaatagtcgg atagataaag taagatatat gttcaataaa ataacttagt gcgttttatg
     1321 ttgttatata aatatggttt cttattaaat aagatgaaat attctttaat atagatttga
     1381 attaaagtgg aaaggaggag attgttatta taaactacaa gtggatattg tgtcctattt
     1441 gtggaaataa aacaagacta cgaatacgag tggatactat acttaaaaat ttccctttat
     1501 actgccccaa atgtaagaac gaaactttaa ttaatgttca aaaaatgaat ataataacaa
     1561 tcaaagagcc agacgccaag acgcagagcc gataatttga gaaatgaaac tctcatctta
     1621 tcggctcttt ttgtttatct gaattttact gactagcctt caatatttct tgcttcattg
     1681 ataccttttg ctagtgcttc cattaaggat agttctttgt ctgtaaagct atccatgtat
     1741 ttttctacct gtaaccttcg agtgctttta atcaaattat ctgtaggtaa gaaaaattca
     1801 tcaatagata catggagtaa tgatacaaga tcatacagca cttgtgtact tgggtgttgt
     1861 cctttgtttt ctatatttgt taaataacgt gggtcaattt caatcattgt tcccacttgt
     1921 tcacgagtga gaccccgttt cattcgagcc tctttaatcg ctaaaccaac ggctctaaaa
     1981 tcgtatttat cttctttttt acgcatacta aatcacctct atacatttta ctgttcctat
     2041 ataaccataa acaggtatag aaaaacatgt tatatagttt atgagttcct atagaacact
     2101 gtggaattta ttaatgcgat gaatccaatt tcaaatagaa aggtcgctga ttttatttac
     2161 ctatacaact ttataaaatt tagtcatact cctagaaagt agataaaatt ggcgacttaa
     2221 tggagggaaa agtcgccatg agaaagataa tctgtcatct agttctctta attaagttct
     2281 tatcaaaaaa acttatccac ctgtactgga tagatatgac catcaatgtg gttttgcaga
     2341 ttacatagat agaaaaatca aagcatatga acagagaaaa caatctgttt atgtgctttt
     2401 ttggtcactt aataaatatc ttttaggatt tctcttcatt tatgcaacaa atcccccgtt
     2461 cgtgtcgggg tttagtatga agggagataa agaagcacat gccactccct ttcacgacag
     2521 aaagggggtg aaaagcatga aaccatcttc ttttcaagaa accatagaaa atcagtttga
     2581 ctatatctgc aaacaagtta ttgaagatga acgaaaagat tacttcaaac atctagacag
     2641 actatcagca aaagaagtct cgttttctga tatagataac taccttgtca actctttttc
     2701 tactgttgat acgtacgtca ctgatttcca actatttaaa ttatttggat taagaatcaa
     2761 tgttgaaagt gatttattaa gtgaagccct gcgtcatctt tcagagaaaa aacggaacat
     2821 tattttactt cattacttta tggatatgag tgatgtggag attgcggagt tactaaattt
     2881 gaatcgttcg actgtttatc gtcatcgaat aagtggacta gccatgatta aagaattcat
     2941 gaaggagtgt aaagaatgaa aacagcttat ccaagggttc ccttccccct cattgtaaag
     3001 gcgacagatg gcgacgtgga agcaattaat cagattgtta aacattatcg agggtatacc
     3061 tcaaaacgtt cattacgtcg catgacagac gaatatggaa attctcatat ggttattgat
     3121 gaaaccctac gtggcagaat ggaaacgaaa ctcatctcta agattttatc gttcgaaatt
     3181 aaatagtccc attttttcgt ggaagcgtgt cgaatcgtat ccacgcttcc cgatttggga
     3241 ggtttgttat tccatcaaag catattgtgt gttcagtagg ttttgatagg ctaacaagcc
     3301 aaacgttctt tgacaaccaa ataaaggcaa tcgaatacgt ttcggtaaga aaagagctga
     3361 tgaactaaca cgccatgacc tacaaaatta gtgagcgatt catgttagta attcgaaagt
     3421 aatctttagc aggattgctg ccatgacttt cttatcgtga taatgatact cccgtatagc
     3481 catagtccga gcgttagaag cgtcacaggc aatgggtacg gctacatgag aaccatgcag
     3541 aagtgaaatt cctgtgagct ttgctagagc tgttcgattg ctaagatatt cttctcttgt
     3601 cagtgtatta ttataaaact atttgatata attataggtg aatattggag ttttcctagc
     3661 ctataattgg gaaaggagta ataatgataa cggtcacaaa aaaggattta gttgagctag
     3721 gatatggaac ttctttttca gcagacatca taaaaaaagc aaaagaattg atgattacaa
     3781 aagggcatat ctactatcaa tctcgaaagc tagatagagt ccctcgtgaa gctgttgaag
     3841 aaattctagg aattcggttt tcaaatgaaa acaggtctga gtagtttttg cacagtaagg
     3901 agtaaaaact atggttaaag acccaataaa aaaagcaaag aatggaacct attattttcg
     3961 tgcaaatcta ggttatgatt ctaaagggaa aaaaattcaa aaatatcgta gtggattcac
     4021 tactaaaaaa gaagcaagag aagaatattc gaaactgcta ttgatgaaac cagaagaatt
     4081 aagtgagaat aaggataaaa tgacgtttaa acattatatc tttgaaattt tccttccatg
     4141 gtataagaca caggtaaagc tcagaacata tgaaaatcgc ttaccaacta ttaagaagca
     4201 tttctcttat tttgataaaa tggctgtttc cgatattgag cctattgatg tgcaaaattg
     4261 gcaactaaaa ttatcaaaga agtgtaagtc ttcttatgta agagctgttc aaggactatt
     4321 ttcagttgct atggatcgag caattgtcct tgggataacc accacaaatc catctaagat
     4381 tattggcaat gtgaaaaagc aaaagtctaa aattgaattt tggacaaaag aagaatttga
     4441 aaaagtaatc tctctaattt acaaagaaga ttactatcaa cactttttat ttatctctct
     4501 gtggttttta tttatgactg gaatgcgaat tggtgaagct actgccattc aatgggaaga
     4561 tattgatttt gactcaggag tactaaccat caacaaaaca ctctattaca agaatcaatc
     4621 gaattataga tttgttgaac caaaaacaaa ggcgagcgtt cgtcatattg tattagataa
     4681 atgcacatta acttatttat ccgaatggaa ggaagtacaa caaaatctaa ttcagacaga
     4741 ctttgtaatg agctataacg gtattcctac ccaaaaacat acactatcat atgctattga
     4801 acgctatgct aagctggctg gtatccatcg aatcagaatc catgggttac ggcattctca
     4861 tgcttccttg ttaatcagta tgggagaaaa tccacttatc attaaagatc gtctaggaca
     4921 cgaagatatt gagacgactt taggaacgta tggacatctt tatcctaaca gtaatttcga
     4981 ggtagctaac aaattaaatg gagccatttc ctttaaagaa gcaaaacaaa attatgatac
     5041 ttcaccaaag aatcaattta ctgtagacta cttgcgaaac aaagaaatga aaaaagtgca
     5101 ataaaagtgc agtaaaaaga taagaagagc cagaaaccct tggtataaga ggatttctag
     5161 ctctcctaca actattccca ctccactgtt gctggtggtt tagaagtgat gtcatacacg
     5221 atacggttga cgtgggctac ttcgtttacg atacgtacag agattttttg caagacttcc
     5281 catgggatac gggcaaagtc agcggtcatt ccgtcgattg aagttacagc acggataccg
     5341 actgtgtagt cgtaagtacg tccgtcaccc ataacaccga cagagcggat ccctggaaga
     5401 acagtgaaat attgccagat atcacggtca agtccagcag ctgcgatttc ttcacgcaag
     5461 atagcatcag attcgcgtac gatttctagc ttgtcttcag tgatttcgcc aagaacacga
     5521 ataccaagac caggaccagg gaatggctga cgccaaacga ttgaatcagg catgcctaac
     5581 tgagtcccta attcacggac ttcgtctttg aataatgtgt ttaatggttc gatcaattca
     5641 aattgcatat cttctggcag tccacctaca ttatggtgag atttgatcgt ctgtgctgtt
     5701 tctgtaccag attcgataac gtcagtatac aacgttcctt gtgctaggaa agagacgcct
     5761 tcttcaccag caagttttgt tgcttcgtca tcaaaaacat atacgaattc attcccaatg
     5821 attttacgtt tttgttctgg gtcagataca cctttcaact tgtctaagaa gcgatctctt
     5881 gcatcgactt tgatgatgtt caagccgaat tttccgccta gactttccat tacttgttcc
     5941 gcttcgcctt tgcgtagcag accgtggtca acaaagatag atgtcaattg gtcaccgatc
     6001 gctttttgta aaagaacccc aacgacacta gaatcaacgc cacctgaaag accaagcaag
     6061 acttttttgt caccaacttg ttcacggatt ttttctactt gcatatcgat aaagttatcc
     6121 attgtccagt taccttcaca gtgacaaaca tcaaaggcaa agtggcgcag caattcgatt
     6181 ccgtattcgg aatgacgtac ttctgcatgg aattggatac cataaaaatt acgtgttgtg
     6241 tcttggatag aagcaatcgg acaatctttg cttgttccga ctgtttcaaa gccttcagga
     6301 actttagtta ccaagtcacc atggctcatc catactgttt gttgttttgg tgtttcttta
     6361 aacaagacag cttgatcgct tgttacttct aacaaggctt tcccatattc gcggttttta
     6421 gcaggctcta cggaaccgcc aagtttgtac gtgatcaatt gcataccata gcaaatccct
     6481 aatacaggaa tacctaaatt gaagatctca ggatcgatcc caaatgcatt ctcatcatat
     6541 acactgtttg gtccgccaga aagaatgatt ccctttggat tcatcgcttt tacttcttct
     6601 gcagtaatgc ggtggctcaa taattcggaa aagactccaa gatcacgaat acgtcttgtg
     6661 atcaattggt tatactgact accgtagtct aatacgataa tcttttcaac gttcgtcata
     6721 tcggcaacgt ttgtcaaatt tattacccct atccctttaa attttatctc aaaatagtca
     6781 aactatttta aaatgctaat attttcgcat gaaaatcgaa tcgatgatat gattttcagt
     6841 tttatggaga attatatcgg ctcttcctcg tgtaggcaag atatattcct gtaaattttt
     6901 caaattcaca tttttccata catcttttgc cattttaaag gcttcttcac gatctccgat
     6961 agcaaaacga taataataat tctctggatt ttggaaagcc gtatccagta acgcaccaaa
     7021 acgatccaaa taccattttt cgatcagcac gggatcggca tcgacataga cagaaaaatc
     7081 aaaaaagtcg ctgacgtaga tttgctgatt cgcaggtaat tgaagcgtat tgatcccctc
     7141 aacgatcaag atatcaggct gctggatcaa ttcgtacttg tctggaatga tatcatacac
     7201 atcatgtgag taaacaggta cttttatctc ttcctgacca gattttacac ggttcaagaa
     7261 atcgatcagc atctccatat cataactttc aggaaatcct ttacggtcca tgattccacg
     7321 ctcttttaat atacgatttg gataaagaaa tccgtcagtc gtgatcagct gaacgtttct
     7381 tcgtttgaag gtacgagaca aaatcgtctg cagcagtctg gctgttgtac tttttccaac
     7441 ggctacactt ccggcgatcc cgataataaa aggcggtact tctacgtatt tatgaagaaa
     7501 taaaccttta ctcaagaaca aagattcaaa ttctttcata taaagataaa tcagatgagc
     7561 aagaggtaca tagatatctc gaacatcctg catggaaatg cggtcattca aacttttgat
     7621 attatctagt tcatcttgtg tcaaaggtgc ttgcccatta cgataaaatt ctcgccattc
     7681 ttctcttgcc acacggtagt agttcattgg atcattcata ttagcctcct gcgttctccc
     7741 atcaatggaa ctattttaac acaaaataaa cgcaaacccc accacttaag agagattgcc
     7801 gatctttttg tataatcttt ataatagaaa gaaacggagt cttattcttg acttgcgcac
     7861 ggatacataa aaggatagac tgttgtcatg aaagaaatga gaaggatgga agacatgaca
     7921 aatcattact attctgaacg cccagatacg gcgcacgatt ttgaacaatg ggcttttgag
     7981 ttaaaaggca gaacctttca atttgtaaca gattctggtg tattttcacg tgaaacagtg
     8041 gattatggtt cacgtgtcct gattgatgct ttcgattggg aagagttacc tgatgaagga
     8101 aagatcttag atgtgggatg cgggtatgga ccgattgggt tagctttggc atttgcgaca
     8161 cagcggtttg ttgaaatggt cgacattaat gaacgagcgg taagtctagc gcaaggaaac
     8221 gcaaagcgta accaaatcga acatgttgat atccatcaat cgaatatcta tgaagcagtt
     8281 catgaagaaa cctatgcagc tatcgtaagc aatccgccga tccgtgctgg aaaaaaagtt
     8341 gtacatgaaa ttttgacagg cgcatatcct cggttgaaga agggcggtac actgacaatt
     8401 gtgatccaga agaaacaagg agcgccgagt gcgcaaaaga aaatggaaga aacatttggt
     8461 aatgcagaaa tcgtcacaaa agataaagga tattatatca tcaaaagtgt gaaagaataa
     8521 ctagctgaaa aatagtggag cgacgaaaga gtggaactgg gcgtgcatgt acgggtacgt
     8581 atcagttctt tttttgttga gaagttttta aaaacaaaga actatttttt cttcaaaaag
     8641 aaatagtagg aacagagtcg ttgtttttta cgataaaata aataagatac agaacttgta
     8701 tagaaggctg ccaagtcggt agataaagga ggtttttatc aaaaaacata ctttcctttt
     8761 ttctctattc ttttcttggg ggttttggta cactgatagg gaatttagat agaagggagc
     8821 caataggatg aagctgacca tcagagatat cgcagaaatg gcaggcgtat cagtaacaac
     8881 tgtctcacag attttgaata acaaaggaag cagatttagt gataagacaa gaaaaaaagt
     8941 gttgtcgatc gtgaatgaac atcattataa gcccgattat ttcgcttcaa atgtgatcaa
     9001 tcgacattca aagaccatcg gaatgatcgt ccctgatgtc actgatttct tcttctccaa
     9061 actgatcgaa ggtgtagaga gctatttgaa tcctttgggc tatgtgatca tgttatgcaa
     9121 ttctcgtcat agccaagaaa atgagatcaa gtatttacaa gagctttccc accgctcagt
     9181 ggacggaatc ttgctggcca caccaaatat tttacctgag aaatatgcat tagacagcgg
     9241 tttttatcaa aaaatgccaa tcattttaat cgatcgcgga ttgaatcgtc gggataacgg
     9301 acggcttatc gtaaaggaat atgagggcgc ctatcaagct gtttcgctgt ttattgaaaa
     9361 tggccatacg aagatcggca tgctgaagga aaccactgga tactatcaat tagaagaacg
     9421 tttcaacgga tatcgtcatg cgctgaaaga tcatggcctg ccttttaatg ggaaatttgt
     9481 tgaacatgga gagttgactg tccaaggtgg atatactgca tcaaaaaaat tactcaaaca
     9541 taaagatatc acggctattt tttgcgggaa tgatgccatg gcgatcggat gctatcaggc
     9601 gatcgatgaa ttgggcaaaa aaatcccaga agatatctca gtcataggat tcgatggatt
     9661 aaagctgtca gaatacatga ttccgcaatt gacgacagtg cagcagccaa gttttgatat
     9721 tggattttat gctgcacgtt tcctgatcga tacgatcgaa tttcctcaaa gaaaagttcc
     9781 gaacaaagtg ttcgaaacaa aattaattat tcgtgagagc gtaaaagtat tgacaaaggg
     9841 ctaactcggc ggtatattgc ttatgtaagc atttacaaag gctagttagt gcttttttta
     9901 tttttagtaa accagtttac taaagtggtt tacctttcct aaaaataatg tataataccg
     9961 aatgaagaca aggaggatca ggcaatgcga atggtggatc tgattgaaaa aaagagggat
    10021 ggaaacgagc tgtcgaaaga ggaaatcgag tacatcgtca cgaactatac gaatggaaag
    10081 attccagatt atcaagtcag tgcattattg atggcaattt tttatcaaga catgacaaat
    10141 gaagaaatca cgaacttaac attggcgatt gctaattctg gtgatgtcat cgatttgagt
    10201 tctcttgaag gaataaaggt agataagcat tcgacaggtg gcgttggtga cacgaccaca
    10261 ttgattttag cccccctagt agctagtgtc ggagtgacag tggctaaaat gtctggacgc
    10321 ggtctaggtt acacaggtgg tacactagac aagctagaag caattcccgg atttcagatc
    10381 gagctttcgg atgaagaatt tgtacgcatt gttaatgaaa gtaaagtagc ggtaattggt
    10441 caatcaggaa acttggcacc ggcggacaaa aaattgtatg ccttgcgtga cgtcacagcg
    10501 accgttgatt ctcttccgct gattgccagt tcgattatga gtaaaaaaat cgcggcagga
    10561 gcagatgcaa tcgttttgga tgtgaccact ggagacggtg ctttcatgaa gaacatcgaa
    10621 gatgcaagac gtctggcaaa gaccatgacg agcattggga aactggctaa ccgagaaaca
    10681 gtggcggtta tctcagatat gtcagaacct cttggcgaag ctatcggaaa tagtctagaa
    10741 gttgtcgagg caatcgaaac attacaagga aatggtccag aagatctagt agaaatgtgc
    10801 tacgccttag gaagccaaat ggttgttctt gctggcaaag ctaagacaac cgatgaagca
    10861 agaacgttgc ttcaagaagc tctggaatca ggtaaagcgt tagcaaaatt caaagaaatg
    10921 atccaaaatc aagggggaga cccagcgatc gtggaacatc cagaacgaat tttgactgca
    10981 cgctacacaa tggagcttcc tgctaaacaa agcggagttg tgtcaaaaat cgtggcaaat
    11041 gaattaggaa ttgctgcaat gatgctaggt gctgggcgta aaaccaaaga agaagatatt
    11101 gatcacgctg ttggattgaa actgcataaa aaaattggtg acactgtgac aaaaggtgag
    11161 tcactattga cgatctatag taacgacgaa gaaatcactt ctgtcattga attattatat
    11221 aaaaatattg aaattggtga atcggcaatg aagccaacgt tgattcatga catcatcaca
    11281 gaataaagga aaaaagcgga ctttaccgtt ttaaagaaaa ggggaaaaga aatggaacta
    11341 aaccgaatga tcgaccatac tattttgaaa gcagacgcat ctaaagaagc tgtgatgcaa
    11401 attatcgaag aagcaaaaaa ataccatttt tattctgtct gcatcaatcc agcatgggtt
    11461 gcgctagcga aagaacaatt acaaggtgag ccagtagccg tatgtacagt aatcgggttt
    11521 cctctaggag caaacacacc cgagacaaaa gcatttgaaa caacagatgc catcaataac
    11581 ggtgcagatg aagtcgatat ggtcatcaat atcggtgctt tgaaatcaaa ggatgatcaa
    11641 caagtccaaa aagatatcga agcagttgtt gaagcagcaa aagatcgtgc gcttgtcaaa
    11701 gttattattg aaacatcgtt attagataga gaagaaatca tccgagcttg cgaaatagca
    11761 aaagctgcag gcgctgattt tgtcaaaaca tcaactggtt tctcaacagg cggagcaaag
    11821 gtagaggatg tccgtttgat gcgtgaaact gtaggaccag aaatgggtgt caaagcttcc
    11881 ggcggtatcc ataacgaaga agaagcaatg gcaatgatcg aagctggtgc tacaagaatc
    11941 ggaacaagcg caggagtagc aatcgtatct ggttcaactg gtgaaggcta ttaatttttt
    12001 caaaggagaa gctcatggca gaactcaaac aagaatggat caacacagct attgaagcgt
    12061 tagataaagc ctatgttcct tattcccatt ttccggtagg cgcttgtctc gtaacggaat
    12121 caggcaagat ttatcaaggc atcaacattg agaatgcatc atttggatta acgaattgtg
    12181 ccgagcgcac agcttttttc aaagcagtat ctgaaggaga aaaaacattt acgcatctag
    12241 tcgtagcggg gcacaccccc gatcctatct ctccttgtgg tgcatgtcga caagtaatgg
    12301 cagaattctg ttcccctgat atgccggtta cgctagtagg agacaatggt gtgacgaagg
    12361 caacgaccgt tcgtgcactg ctgccttatg catttactga aaaagatcta taactcatgt
    12421 tcattcagtc agctgactgt tgaaaaataa aacaattatt ttaggaggct ttacagaaat
    12481 gaaaaaagca aaattatttg gtttaggtgc tgtcgcacta gcagcagggt tatttttagg
    12541 tgcatgcggc aacaacggct ctactgattc atccggtggc aaaagctcat cagacacaac
    12601 aactgcagca ttgatcacag acacaggtgg tgtagacgac cgttcattca accagtcagc
    12661 ttgggaagga ctagaaaaat gggggaaaga tcaaggactt tcacgaggaa atgatggctt
    12721 ccaatatttc caatcttcaa atgaatcaga ttacatccca aatattgacc aagcattgaa
    12781 tgctggattc aaaacgattt ttggtattgg ttataaacta aaaccagcga tccaagaaca
    12841 agcaacaaac aatacaggta cgaactttgt tattatcgat gatgtcatcg atggattaga
    12901 taacgttgta tctgcaactt tcaaagacaa cgaagcttct tatcttgcag gtgttgcagc
    12961 agcttatacg actgaaacaa acgtagtcgg ctttatcggc ggtgtaaaag gtgaagtaat
    13021 cgatcgtttt gatgctggat tcaaagccgg tgttgatgca ggtgcgaaag aattaggaaa
    13081 agaaatcaaa gtattgaatc aatatgctgg tgacttctct gctccagata aaggacgttc
    13141 aattgctcaa ggtatgtatg cacaaaacgc agatatcatc ttccatgctt caggcggtac
    13201 aggtaacggt gtattccaag aagcaaaatc attgaacgaa tcaggcgaca aaaaagtttg
    13261 ggttatcggt gttgaccgcg accaatcaga cgaaggcgaa tacacattaa acggcgaaaa
    13321 gaaaaacttc acattgacat ctacactgaa agcagttgga acagtagtag aagatttggc
    13381 acaaaaatca gcggacggta aattccctgg cggcgaacac actgtttatg gattgaaaga
    13441 agacggtgtt ggtctaacag aaggacaact ttctgacgaa gcgaaaaaag cagttgatga
    13501 agcaaaagaa aaaatcattt caggtgacgt aaaagttcca gaaactcctg aagaaaacta
    13561 aaaccatttc tatagccttg ttagacacat gtttgacaag gctatggttt gattagaaca
    13621 agaattgttc atttatccaa gctgccttgt gacagtttgg ataagggaac aactccctga
    13681 agtaatgttt gtttcaaaag aagaacgctc actaagcgtg aatcttagtc aatcgttgcc
    13741 ctagatagaa atcgttagga tgtgaaaaaa aggtggttca agaaaatatt gtcatagaaa
    13801 tgcagaatat taccaaagaa tttggaacat tcaaggcaaa tgacaacatc aatttacaag
    13861 taaaggcagg agaaattcat gcgttgcttg gagaaaacgg tgctggcaaa tctacattga
    13921 tgaacgtgct ttccggatta ttagagccga catcagggaa aattttgatg cgtgggaaag
    13981 aagtaaagat cacaagtccg accaaagcca accaattagg gattgggatg gtccatcagc
    14041 actttatgct tgttgatgcc tttactgtaa cagaaaacat cgtgttggga agcgagccta
    14101 gtcgcgcagg gatgcttgac cataaaaaag cacgaaaaga gatccaaaaa gtttctgaac
    14161 agtatggatt gtcagtcaac ccagatgctt acgttcgtga tatttcagtt ggaatggaac
    14221 aacgggtaga aattttaaaa acactttacc gaggagcaga tgtactgatt tttgatgagc
    14281 cgacagctgt attgacccct caagaaattg atgaattaat cgtgatcatg aaggaattag
    14341 tcaaagaagg caagtcgatc attttgatta cgcataagtt agatgaaatc aaagcagtag
    14401 ctgaccgctg tacagttatc cgccgtggaa aaggaatcgg tacagtcaac gttaaagacg
    14461 taacctcaca acaattagcc gatatgatgg ttggaagaac ggtttcattc aaaacgatga
    14521 aaaaagaagc gaagcctcaa gaagtcgttt tgtctattga aaatctagtg gtgaaagaaa
    14581 atcgtggatt agaagccgtg aaaaacttga acttagaggt tcgtgctggc gaagtacttg
    14641 gtatcgctgg aatcgatgga aacgggcagt cggagttgat ccaagctttg actggtttgc
    14701 gaaaggcaga aagcggacat atcaagctaa aaggggaaga catcactaat aaaaaacccc
    14761 gaaaaatcac tgaacatggt gtaggacacg tgccagaaga ccgtcataaa tacgggttag
    14821 tcctagatat gacattatct gaaaatatcg cactacaaac ctatcatcaa aaaccttaca
    14881 gtaaaaacgg catgctgaat tattcagtaa tgaatgaaca tgccagagaa ttgatcgaag
    14941 aatatgatgt tcgaacaacg aatgaacttg ttcccgcaaa agctttatca ggcggaaatc
    15001 agcaaaaagc aattatcgct cgtgaagtcg accgagatcc tgatctgttg attgttgcaa
    15061 atccaactcg tggactggat gtaggtgcga tcgaatttat tcataaacgt ctgatcgaac
    15121 aaagggacaa atacaaagca gtgttactga tcagtttcga attagaagaa attttaaatg
    15181 tttcggatcg tattgctgtt atccatgaag gagaaattgt cggtatcgtt gatccgaaag
    15241 aaacatctga aaatgaatta ggtctattga tggcgggcta taccttagaa gaagcacgaa
    15301 aagagttaga aaagggggct ggcgcacatg aatgatcgca gcgaaaaatt ccgtaattta
    15361 ttagtgcctg tactttcagt tgttttagga ttgatcttag gcgcgatatt gatggctgct
    15421 tttggttttc agcccatcca aggttattct tctatgctag atgcagccct tggttcgcaa
    15481 agagggatag gtgaaacgtt aaggcaagca acgccgttga tttttacagc attaggtttt
    15541 tctgtagcta actcagctgg gtttttcaat attgggcttt ctggacaagc actttgcggg
    15601 tggatcgtca gtgtctgggt ggcacttgcg tttccagatc tgccaaaagt tgttttgctt
    15661 ccgttatgcg tgatcttagg tgccttagct ggtgcgatgg cagcggctgt tccaggttta
    15721 cttcgagcat tttttggaac aagtgaagtg atcgtaacaa tcatgatgaa ctatatctta
    15781 ttatacgtaa gcacatttgc tttacatgaa gtgatgcctg aaagctatcg ctcaagtttg
    15841 gactcttcca atatgatcag tcaaaatgcc tcactgcggt taccatggtt aacacaagct
    15901 tttggcggct ctcgcgtaaa ctcaggatta tttttagcaa tcatcgcgct tattttcgtt
    15961 tggctgctga tgaagaaaac gactttagga tttgaaatcc gttctgttgg attgaatcct
    16021 tttgcttctg agtatgcagg aatgagtagt aaacgtacga tcgttttgtc gatggtcatt
    16081 tctggcgctt tggcagggct tggcggtgtg gttgaaggat taggaacgta tcaaaacttc
    16141 tttgttcaaa cgacttcgct atctattgga tttgacggaa tggctgtttc cttgcttggt
    16201 tctggatcag caatcggtat tcttttatca gcgatcttgt tcagtatttt gaagatcggt
    16261 ggacttggca tgcagacagg agcaggtgtt ccgtttgaga tcgtcaatgt atcgattgct
    16321 ttgattatct tctttgtcgg gatcaacttc ctgattcgtt tcgtcatggc taaagtcttc
    16381 caagggaaaa aacaagaaga gatcgttgcg acaatagaat cgaaaccaac gaatcaaaac
    16441 catgaagggg gcgaactata atgtcgacta tcgaattaat tgccttgatc cttacttcta
    16501 cactggttta ttcaacaccg ctaattctaa cgtcactagg cggaactttt tctgaacgaa
    16561 gcgggatcgt aaacgtaggg ctagagggaa tcatggtcat gggtgctttt agttccatcg
    16621 ttttcaactt gacgatgagt ccatcacttg gttctatgac accatggatc gctattttag
    16681 tgggtggcgt cgtaggtatc ctattttctc tgattcacgc agtagcaaca gtcagtttgc
    16741 gtgctgacca tattatcagc gggacagtaa ttaatctgat ggcacctgct ttaggtgttt
    16801 tcttgatcaa agcatggtat ggtaaaggtc aaactgataa catcacgcag aatctggggt
    16861 atttttcttt cccaggatta gcagatattc cggtcattgg accaattttc tttaaaaata
    16921 cattcttacc tgcttattgt gctattttga ttgctgtcct agcttgggtg atcatcttca
    16981 agacgaaatt cggcttgcgc ctccgttcag ttggtgaaaa tcctcaagct gccgacacat
    17041 taggtatcaa tgtatatgct atgcgttatt caggcgtact gatttctggc ttgttaggcg
    17101 gtatgggcgg tgctgttttt gctcagtcga tttccggtaa cttttcagct ggtacgatcg
    17161 ttggacaagg gttcatctcc atggctgcta tgatctttgg taagtggaat cctttagggg
    17221 caatgggtgc ctcattgttc tttggttttg ctcaaagctt gagtatcatt ggcgcacaat
    17281 taccagttat ttcttcgatt ccgccagtat tgctgcaaat tgctccatat ttgctgacaa
    17341 tcattgtgct ggttgttttc ttagggaaag cttctggtcc aaaagcaaac gggaagaact
    17401 atatcaaatc aaaataatct tttagcgaat aaaaagggtg ggttacggga agtgtttttc
    17461 gtctcgccct ttttgtttta aaggcaataa aaataaaaag aaagaaggaa taatcatgtt
    17521 taaacgcgta catctgatcg tcatggattc agtaggaatt ggagaagcac cagatgccga
    17581 taagttcggt gatgttggtt ctgatacatt aggacacatt gcgaaagaag caggattgaa
    17641 cgttccacat ttagagcagc ttggtttagg aacgatccgt cctcttgaag gtgtggaatc
    17701 agtgaaagat catcaaggct atgcgacgaa attagaagaa gtttctgtag ggaaagatac
    17761 gatgacaggc cactgggaaa tcatgggatt gaatatcaaa actccatttc gtgtgtttcc
    17821 taatggattc cctgatgatc tgatcaaaca aatcgaagaa ttttctggcc gtaaagtcgt
    17881 atgtaacaaa ccttatagcg gaacagctgt tattgacgat tacggtgaac accaaatgaa
    17941 aacaggcgat ttaattgtat atacttctgc cgatcctgtc cttcagatcg cggcacatga
    18001 agaaatcatt cctttagaag aattatatcg gatttgccaa ttcgttcgtg atataacaaa
    18061 agatgatccg tatatgattg gccgaatcat tgcacgtccg tacgtgggtg aaccaggaga
    18121 cttcacacga acaagcaatc gccatgatta tgcgttgaat ccattcggac acacagtcct
    18181 tgattctttg aaagaagcag gaaaggacgt gattgctgtt ggaaagatca acgatatttt
    18241 caacggacaa ggaatcactg aatctgtccg cacgaaaagc aatatggatg gcgttgacca
    18301 gctgctgaaa gttatgaaaa acgatttttc aggaatcagc tttaccaatt tagtagattt
    18361 tgatgcatta tacggtcatc gtcgggatgt agtcggctat gcgcatgcga ttgaagaatt
    18421 tgacttacga attccagaat tgcttgaagc gatggaagaa gacgacttgc taatgattac
    18481 agccgatcac ggaaacgatc cgacgtttac tggtaccgat catacgcgag aatatgtacc
    18541 gttattggtt tacagtaaaa aaatgaaaga acaaggggca ttgcctcaag gatattattc
    18601 agatatttca gcaacgattg ctgagaactt tagtgtttct tcgactgaaa atggcgaaag
    18661 cttcttgaaa ttattaaaat aatcttttta aataggagaa agcaaatgac caagttaagc
    18721 gagatgttac aagaaacgac ccagtttatc cttgataaag gagtaaaaga aattgatttt
    18781 ggtttgattc taggttcagg attaggtgaa ttagcagatg aaatcgaaga tgctgtaatg
    18841 atttcttatg atgagatccc gttctttcct gtttcgacag tagttgggca tgcaggaaag
    18901 ctagtttatg ggtctctggc aggcaagaaa gtgttagcca tgcaagggag attccactac
    18961 tatgaaggtc attccatgca aacagtgacc tatccagtac gtgtgatggc cggactaggg
    19021 gcccattcag tcattgtgac taatgcatgt ggtggtgtca acgaatcatt tgtaccagga
    19081 gatttgatgc tgattaccga tcatatcaat tttactggtg aaaatccttt gatcggtccg
    19141 aatgaagatg caatgggccc tagatttcca gatatgagtc aagcttatac gcctgactat
    19201 caagcaacag caaaagcagc agcagaaaaa ctaggtttgg atcttaaaga aggcgtatat
    19261 atgggctatt ctggaccaac ttatgaaacg cctgcggaga tccgaatgtc tcggacaata
    19321 ggagccgatg cagtagggat gtcgactgtt ccagaagtca tcgtagcagc tcacagcgga
    19381 ttaaaagtgt taggaatctc ttgtattacc aacttagcag caggtatgca agcgaatctg
    19441 agccatgaag aagttgtaga aacaactcag agagtcaaac aatcttttaa agcattggtt
    19501 aaagaaacat tgacattatt gtaataggag gaacaataaa atgagtgtgc atattgaagc
    19561 gaaagaaggc gagatcgccg ataagatttt acttccggga gatcctttgc gagctaaata
    19621 tattgcggag acttttttgg aagatccagt ttgttacaat caggtacgcg gtatgttagg
    19681 ctttaccggc aaatataaag gagaacgtat ttctgttcaa ggaacaggaa tgggaatgcc
    19741 atcagccacc atctatgccc atgaattgat ccagtcgtat ggtgtaaaga aattgattcg
    19801 agtaggtaca tgcggtgcat tgtcaaaaga cgtccatgtt cgtgatttag tactagcaca
    19861 aggtgcagcg accagttctt cgatgatcga aaaaaatttc caagcctttc attttcctcc
    19921 aatcagtgat ttcaatctat tactgaaagc atatgagata gctaaagaaa agggctatac
    19981 ggttcatgta ggaaatgttc tttcggaaga ttctttctac aaagatgatt tgacagagac
    20041 gttccaatta gctgaacttg gcgttttagg agtggaaatg gaagcagcgg ctctttatta
    20101 cttaggcgcg aaataccatg tgcagacatt aagtttgatg accgttagcg accatttgat
    20161 caccggtgaa gaaacaacag ctgcagaacg tcaatctacg ttcaatgaaa tgatcgaagt
    20221 aggattggaa acagcgatag cagaataaga aggaaatgaa aaagctgccc tgcattaagt
    20281 aataagaaca tccaagcaaa aatagctcct catgtttttg acttggctgg acttattatt
    20341 gcaaatgtaa gcttttgaac accgtttacc aagaggttgt gaatctgccg tttaactctg
    20401 agtcacaagg aacaatttca aaaaacagct tttcatgttt gatgaatatt gtgacttgtg
    20461 accgagaagt tggcaggaga aaaccgttta tacgaaaaaa gggactgtga caaatcgtgt
    20521 cacagtccct tttttatagt gttttttata ggtagtattt tttagcaact gttaagtcat
    20581 catttaattc ataaacaagt ggttgacctg ttggaatttc aagatccatg atgtcttcgt
    20641 cagagatacc ttcgatatgt ttagctaggg cgcgtaatga gttaccatgt gcagctacta
    20701 aaacagtttt gttgtctagt aatgctggag caatttcatc ttgccagaat ggcaaagcgc
    20761 gttctaatgt cactttcaag ttttctccac caggaatatc gcgtttgtct aacattgcgt
    20821 aacgacggtc atttgctgca gaaccttcgt cagtttcttc cattaatgga ggaagagtat
    20881 cgtaagaacg acgccagatg tgcacttgtt cgtcgccgta tttttcagct gtttcttttt
    20941 tgttcaaacc ttgtaattta ccatagtgac gttcgtttaa gcgccatgat ttgatttgtg
    21001 gtacccaaag ttgatctgaa tattctaaga tcaagttaca tgttttgatt gcacgagtta
    21061 aaacagaagt gtaagcaaca tcaaattcga ttccagcttc tttgattttg cgtccgcctt
    21121 cttttgcttc ttcgattcct tctggtgcta gatttacatc agcccaacca gtaaattggt
    21181 tcaatgcatt ccattcacta agaccgtgac gagaaaaaac taattttggc atgtttagct
    21241 ctccttttaa gataggttta tatttctgaa attttcagtt ctgttttatt gtacaatttt
    21301 ttggaagaga tttccatcga aaaattagat aagattctat gagaaaacaa gtagagaata
    21361 taaaaaaacg aacagtgccc acgcaactgt tcgtttttag gtattagatg cataattgct
    21421 cgatttcttt ttcaggtaaa ttgatatatt tataacatgt tccaactgaa acaccgcatt
    21481 ttgaagaaat aaattggatc gtttcttttt tttcataata gagacgtcgg atttttttga
    21541 tcgtttttgc atcgattttt ggtcttccgc cgatttttcc ttttttacga gcttcatcta
    21601 atccaactaa tgtacgttct ttgatcaatg cgcactccat gtttgctagg ttttccatta
    21661 attggaaata gatttttccc atttcgcgcg tatcgattcc ttcatcaaga ctaatcaagt
    21721 gcagcccgcg atctttgaat aattgcgtga gttctgttaa ttgccgcgta gatttgccta
    21781 atcgatgaag ttggcaaatg actagtgcat cgccttgttg catgtcagcg atcactgact
    21841 ccaaatgaac agcagtagaa tcattttgtt ccacttcata tgtctcatgg aaaatttctt
    21901 gacaaccaaa gtcagataat tgatcaacct gagttgttaa atcaacgtca tttatggttg
    21961 tgcgtgcata accaataatt ttcatggtga ttcctttcta gcagtgattt tctaactgga
    22021 tataacagta aaaatgtagc ataaagtacg tcaaaaagat agttttttcg caaattttcc
    22081 gctgtctttt tttattggat gatcaagcag tttttcttta tttacgacgg attgcgtcaa
    22141 gaatctcaac gcctttttct gagccgacaa ctactttaga aaccatgttt aggaaaagcc
    22201 catgttctac taccccaaca agttcatcta aataggtagc taagctttct ggctgttcga
    22261 tgacttctag atgcagatca atgatgtaat gaccaccatc tgtggttaag acttctccgt
    22321 tttcgtctgt acgcaagacg ggttggaatc ttttttcttc aaaaatatga agtagctgtt
    22381 gggagccata agggatcact tcaactggga gtgggaactt cccaagttta tcgactaatt
    22441 tagaagaatc aacgatccaa atcgtttctt ttgagtacgt agcgactatt ttctcgaaaa
    22501 gcaaagcagc gccgccgcct ttgatccctt gaaaatcagc actgatttca tcagcaccgt
    22561 ctattgtcaa atcgactacg gggacttcat caatactctt taacggtatt cctaattttt
    22621 ccgcttgttc ttttgtcgca tttgaagtag taactcctgt gatacgtaaa ccttcttcac
    22681 gcatacggcg accaatctct tctaccatat aataggcggt tgaaccggtc ccgagaccta
    22741 cgatcatccc gtcctttacg aatttcgcgg cttcaatgcc agctaattgt tttaaattca
    22801 tctttgcgtc cacctttttt tagtttgagc atcgtgcttt cctcactatt ttagcgtgat
    22861 ttacggtaaa aagataccat tcttttttat tccaataaag ctttttcaaa aaaaattgca
    22921 tctcttgttg acatgttttt tcattcgtga tattctaaca aaggtgcttt atctacaggt
    22981 ttctgtgaag aaacgtgctg actgtttatc aaagcatatt tgataaggat gcagacattg
    23041 catttatttt ttatcacaaa aaaagaacca cctggatgtg tggaactaga cgcaaatcgt
    23101 gggaaggagg aaacaaggaa tgcctacaat taaccaatta gtacgtaaac ctcgtaaatc
    23161 aaaggtggaa aaatctaatt cacctgcttt gaacaaagga tataacagct ttaagaaaac
    23221 tcaaactaac gtaaactcac ctcaaaaacg tggggtagca actcgtgtgg gtacaatgac
    23281 acctaaaaaa ccgaactcag ctttacgtaa atatgcacgt gttcgtttgt caaacttaat
    23341 tgaagttact gcttatatcc cagggattgg tcataactta caagaacaca gtgttgtatt
    23401 attacgcggt ggtcgtgtaa aagacttacc aggggtacgt taccatatcg ttcgcggtgc
    23461 tttagatact gctggtgtta acgaccgtaa acaaagccgt tctaaatacg gaactaaaaa
    23521 acctaaagct taattttaat tattaaacaa atgaaacttg cttctactat atagaagtaa
    23581 ttactatgaa caatatttcg gaaggaggag ttacggatgc cacgtaaagg tcctgttgca
    23641 aaacgtgatg ttttaccaga tcctatttat aactcaaaat tagtaactcg cttgatcaac
    23701 cgtgtaatgg ttgacggaaa acgcgggatt gcagctaaca ttatctataa tgcctttgac
    23761 ttgatcaaag aatctacagg taacgatcca ttagaagtgt ttgaacaagc aatgaaaaac
    23821 gttcaacctg ttcttgaagt taaagcacgt cgtgttgggg gttcaaacta ccaagtacca
    23881 gttgaagttc gccctgaacg ccgcgttact ctaggtcttc gttgggtagt aaactacgct
    23941 cgcttgcgcg gtgaacacac aatggaagaa cgcttagcaa aagaaatcat ggatgctgca
    24001 aacaacacag gtgcttctgt taaaaaacgt gaagacactc ataaaatggc tgatgccaac
    24061 cgtgcgtttg ctcactatcg ctggtaagat tctctctgtt tggtcggctt ttataagtcg
    24121 acctcagata gtgtccttat ttttagcaac tagatagtaa agagaggaga aacaaggaga
    24181 atgaccagag aattttcttt acaaaacact cgtaatatcg gtatcatggc ccacatcgat
    24241 gctggtaaaa cgactgctac tgaacgtatc ttgtactata ctggtaaaat ccataaaatt
    24301 ggtgaaactc atgaaggagc ttcacaaatg gactggatgg aacaagaaca agaacgtggt
    24361 attacgatca cttctgctgc tactacagca caatggaagg gtcaccgaat caacatcatc
    24421 gacacaccag gacacgtaga cttcacagtt gaagttgaac gttcattgcg tgtacttgat
    24481 ggtgctgtaa ctgttcttga tgcacaatca ggtgttgaac ctcaaactga aacagtttgg
    24541 cgtcaagcaa caacttatgg tgtacctcgt atcgtatttg caaacaaaat ggacaagatc
    24601 ggtgctgact tcttatattc agtatcaact ttacatgacc gtttgcaagc aaacgctcac
    24661 ccaatccaat taccaattgg tgcggaagac gacttcacag gaattatcga ccttgtaaca
    24721 atgaaggctg aaatgtatac aaacgatctt ggaacagaga tcgaagaaac agaaattcct
    24781 gaagaatacc gcgaattagc tgaagaatgg cgcgaaaaat tggttgaagc tgtagctgaa
    24841 actgatgaag aacttacttt gaaatactta gaaggtgaag aaatcactga agctgagtta
    24901 aaagaaggta tccgccgcgc aacagttaac gtagaattct acccagtact atgtggttca
    24961 gcatttaaga acaaaggggt tcaattacta ttggacgctg ttcttgatta cttgccatca
    25021 ccgttagata tcccagctat caaagggatt gaccctaaaa ctgatgaaga agtagaacgt
    25081 cctgcagacg acagcgctcc tttctcagct ttagcattta aagttatgac tgacccattc
    25141 gtaggtcgtt taactttctt ccgtgtgtac tctggtgttt tacaatcagg ttcatacgta
    25201 caaaacgcaa caaaaggcaa acgtgaacgt gttggtcgta tcctacagat gcatgccaac
    25261 tctcgttcag aaatctctga agtttacgct ggagatatcg ctgctgctgt tggtttgaaa
    25321 gacacaacta ctggggacac actatgtgat gaaaagagtc tagttattct tgaatccatg
    25381 gaattcccag aaccagttat ccaagtcgct attgaaccta aatcaaaagc tgaccaagat
    25441 aaaatgggtg tggctttaca aaaactatct gaagaagatc ctactttccg tgctgaaaca
    25501 aacgtggaaa caggcgaaac aatcatcgct ggtatgggtg aacttcactt agatatcatc
    25561 gttgaccgta tgcgtcgtga attcaaagtt gaagctaacg taggtgcgcc tcaagtatct
    25621 taccgtgaaa ctttccgtgc tggcactcaa gccgaaggta agtttgtacg tcagtctggt
    25681 ggtaaaggtc aatacggtca cgtatggatt gaatttacac caaatgaaga aggtgctggt
    25741 ttcgaatttg aaaatgcgat cgtcggtggg gttgttcctc gtgaatacat tccagctgtt
    25801 gaaactggtt tgaaagatgc tatggaaaat ggtgtcttag ctggctatcc attagtagat
    25861 atcaaagcta aactttacga tggttcatac catgatgtcg attcaaatga aactgccttc
    25921 cgtgttgctg cttctatggc attacgtgca gcagctaaga aagctaatcc agtaatcctt
    25981 gaaccaatca tggctgtaga agttgttatc cctgaagatt atttaggtga tgttatgggt
    26041 cacgtaactg ctcgtcgtgg acgtgttgaa ggtatggaag ctcgcgctgg cggccaacaa
    26101 gttgttcgtg cgatggttcc acttgctgaa atgtttggtt atgctacaac tcttcgttct
    26161 gctactcaag gtcgtggtac atttacaatg acatttgacc actacgaaga tgtaccaaaa
    26221 tcagtacaag aagaaatcat taagaaaaac ggcggaaaag ctgaataatt tcttaaaacc
    26281 ggatagtcct gcaaagagat tatccaaaga gactatattt ttaatatagt ttcgtgtaaa
    26341 ataattatcg atgatatggg catgtggtgt accttgtgta catcatatac ctatcagaca
    26401 aataaaaaat atattgtatt tttaggagga cattttaaaa tggcaaaaga aaaatttgac
    26461 cgttctaaac cacacgttaa cattggtact atcggacacg ttgaccatgg taaaactaca
    26521 ttaacagctg caatcacaac tgtactatct aagaaaaacg gcggccaagc tatggcttac
    26581 gatcaaatcg atggtgctcc agaagaacgc gaacgcggaa tcacaatctc aacagctcac
    26641 gttgagtatg aaacagatac acgccactac gctcacgttg actgcccagg acacgcggat
    26701 tacgttaaaa acatgatcac tggtgctgct caaatggacg gagctatctt ggtagtttct
    26761 gctgctgacg gcccaatgcc tcaaactcgt gaacacatcc tattgtctcg tcaagttggt
    26821 gttccttaca tcgttgtatt cttgaacaaa gtagacatgg ttgatgacga agaattacta
    26881 gaattagttg aaatggaagt tcgtgaccta ttaacagaat acgaattccc tggtgacgat
    26941 gttcctgtag ttgctggatc agctttgaaa gctctagaag gcgacgcttc atacgaagaa
    27001 aaaattcttg aattaatggc tgcagttgac gaatacatcc caactccaga acgtgacaac
    27061 gacaaaccat tcatgatgcc agttgaagac gtgttctcaa ttactggacg tggtactgtt
    27121 gctacaggtc gtgttgaacg tggacaagtt cgcgttggtg acgaagttga agttgttggt
    27181 attgctgaag aaacttcaaa aacaacagtt actggtgttg aaatgttccg taaattgtta
    27241 gactacgctg aagctggaga caacattggt gctttactac gtggtgttgc acgtgaagac
    27301 atccaacgtg gacaagtttt agctaaacca ggtacaatca cacctcatac aaaattctct
    27361 gcagaagtat acgtgttgac aaaagaagaa ggtggacgtc atactccatt cttcactaac
    27421 taccgtccac aattctactt ccgtacaact gacgtaacag gtgttgttga attaccagaa
    27481 ggaactgaaa tggttatgcc tggcgacaac gtaacaatgg aagttgaatt aatccaccca
    27541 atcgctatcg aaaacggtac taaattctca atccgtgaag gcggacgtac agttggtgcc
    27601 ggtgtcgtta cagaaatcaa agcttaattc acttaagttt taaagtaaag caacatttat
    27661 tcggacgtaa tcgctcggaa cgaaggtctt aggatctttg ttccgagctt ttttatttat
    27721 tgcaggatca ggaaaaaaga caggagtatt ataaatagaa gaaacacgaa ataaaagagt
    27781 cagtattttc taaatgaaac tttatgaaaa caaaatgttt tttacaagaa aaagccttgc
    27841 tttgtgagtt tatatatatt ataatgacaa aggtgcgttt actttagtga attgcacaga
    27901 cgtaatcaga atgatttcgt cggctaagaa acgagaggtt gcgacacgcc cggacgcttt
    27961 gccacgaacg agcgtgacgg aaattttcgt ggagctatgt ctacttttca aaataggcga
    28021 aggagggaac aagatggcaa aacaaaaaat tcgtatccgt ttaaaagcgt atgaacaccg
    28081 tattttagat caatcagcgg ataaaatcgt ggaaactgca aaaagaactg gagctagcgt
    28141 gtctggtcca attccattac caactgaacg cagtctttac acaatcatcc gtgcgactca
    28201 taaatacaaa gattcacgcg aacaattcga aatgcgtaca cacaaacgtc ttatcgacat
    28261 tgtgaaccca acaccaaaaa ctgttgatgc tttgatgaag ctagacttac catctggtgt
    28321 aaacatcgaa atcaaattat aaaactaaaa caaaaataat ggaggtgtac tcatgaccaa
    28381 aggaatctta gggaaaaaag tgggaatgac acaaatcttc actgaatctg gtgaattaat
    28441 tccagtaact gttgtagaag ctactccaaa cgtagtacta caagtgaaaa caatggaaac
    28501 ggatggctac gaagctattc aagttggtta ccaagatatg cgtgaagttt tatcaaacaa
    28561 acctgcgaaa ggtcatgttg caaaagcaaa cacggctcct aagcgcttca ttcgtgaatt
    28621 caaaaatgtt gagctaggag aatatgaagt aggaaaagaa attacagtag atgttttcca
    28681 agcaggagac attattgatg taacaggtac tacgaaaggt aaaggattcc aaggggttat
    28741 caaacgccac ggacaaagcc gcggaccaat ggctcacggt tctcgttacc atcgtcgtcc
    28801 tgggtcaatg ggtccagttg cacctaaccg tgtatttaaa aacaaacgtc ttgctggccg
    28861 tatgggtggc aaccgcgtaa ctatccaaaa cttggaagtt gtacgtgtcg atgcagaaag
    28921 aaatgttatc ttgatcaaag gtaatgttcc tggagctaaa aaatctttaa ttactatcaa
    28981 atcagctgtg aaagctaaat aattgtagga agaaaggagg aactaaggaa tgccgaatgt
    29041 agcattattc aaacaagatg gaagccaaaa cggtgaaatc acacttaacg aagaaatctt
    29101 cggaattgaa cctaatgaaa gtgttgttta cgatgcaatc gtaatgcaac gtgcgtcatt
    29161 aagacaagga acacacgcgg ttaaaaaccg tagcgctgtt cgcggcggcg gacgtaaacc
    29221 atggcgtcaa aaaggaacag gtcgtgcacg tcaaggatct atccgctcac cacaatggcg
    29281 tggaggtggc gtagtctttg gaccaacacc acgttcttac agctacaaac ttcctaaaaa
    29341 agttcgtcgt ttagcaatga aatctgtatt gtcagaaaaa gttgctgaaa acaacttggt
    29401 agcaatcgaa ggcttgaact tcgacgcacc aaaaacaaaa gaattcaaac aagttcttgc
    29461 taacttatct atcgactcta aagtattggt tgttctagaa aaaggtaacg actttgctgc
    29521 tttatcagca cgtaacttac caaacgtttc tgtagtaact tctgataatg tgagtgtgct
    29581 agacgttgta tcaaatacaa aagtgttagc aacacaaact gctcttactc aaattgagga
    29641 ggtgcttgca taatgaactt actagacgta atcaaacgcc cagtgatcac tgaaaaatca
    29701 atgcttgcca tggatgacaa gaaatacact tttgaagtgg acactcgcgc aaacaaaact
    29761 ttagtaaaac aagcggtaga agctgctttt gacgttaaag tcaaaaacgt gaacatcgtg
    29821 aacgtacgtg cgaaattcaa acgtatgggc aaatatgcag gatatacaaa aaaacgtcgc
    29881 aaagcgatcg ttacattgac tgaagattca aaagaaatcc aattattcga agctgctgaa
    29941 taagcactaa tagataactc attaaattag gagggaaaaa cgtggcgatt aaaaagtaca
    30001 aacctacctc aaatggtcgt cgtaacatga caggttctga ttttgctgaa atcacaacat
    30061 caacacctga aaaatcattg ttacaaccat tgaaaaacca tgctggacgt aacaacaacg
    30121 gccgcatcac tgtacgtcat caaggtggcg gacacaaacg ccaatatcgc gtgatcgact
    30181 tcaaacgtaa caaagataac gttgttgcaa ctgttcaaac gatcgaatat gatccaaacc
    30241 gttcagctaa catcgcgtta gtacactatg aagatggagt gaaagcttac atcttagcac
    30301 ctaaaggact agaagtgggt atgaaacttg tttcaggtcc agaagcagat atcaaagtcg
    30361 gaaatgctct tccattagaa aacattccag ttggtactgt tatccacaac attgaaatga
    30421 aacctggtaa aggtggacaa ttgatccgtt ctgctggtac aagtgctcaa gtacttggta
    30481 aagaaggcaa atacgtattg atccgcttga actctggtga agttcgtatg atcttagctg
    30541 catgccgtgc tacaatcggt tctgtaggta acgaacaaca cgaattaatc aacatcggta
    30601 aagctggacg ctctcgttgg atgcgtaaac gcccaactgt acgtggtagc gtaatgaacc
    30661 ctaatgatca cccacacggt ggtggtgaag gtaaagctcc tatcggacgt aaagcaccag
    30721 tttctccttg gggtcaacca gctcttggtt acaaaactcg taacaaaaaa gctaaatcag
    30781 acaaacttat tgttcgtcgt cgcaaaaata aataattact ttgaccatgt gtcgcacatt
    30841 ttgagaggag gttcaccatg ggtcgtagtt taaagaaagg accttttgtc gatgagcatt
    30901 taatgaaaaa agttgaagct caagcagggg ttgaaaagaa aaaagttatc aaaacttggt
    30961 cacgccgttc aacagttttc ccaagttttg ttggatatac catcgcagtt tatgatggac
    31021 gtaaacatgt accagtttac atccaagaag acatggtagg acacaaatta ggtgaatttg
    31081 cacctacaag aacttatcgt ggacatgctg ctgacgataa gaaaacgaaa cgctaatttg
    31141 aggggaggat aaatccaaat ggcagaacaa atcacatcag ctaaagcaac tgcaaaaaca
    31201 gttcgcactt cacctcgaaa agcccgttta gtaattgacc ttatcagagg taaaagtgtc
    31261 gcagatgcaa tttcaatctt gaaattcaca ccaaacaaat ctgctggaat cattgaaaaa
    31321 gtattgatgt cagcagttgc gaatgcagaa aataactttg acttagatgt tgaaaacttg
    31381 gtagtaagcg aagcttttgt taacgaagga cctacaatga aacgtttccg tcctcgtgca
    31441 aaaggatcag cttctccaat caacaaacgt acaagtcata tcacggtagt cgtatcagaa
    31501 aaataaggag ggataatcag tgggtcaaaa agtacatcca attggaatgc gtgtaggcat
    31561 catccgcgac tgggatgcta aatggtatgc tgaaaaagag tatgctgagt tcttacacga
    31621 agatttaaga atccgtaaat ttatttcaac taaacttgct gatgctgctg tatcaacagt
    31681 tgaaatcgaa cgcgcaacag gtcgcgtaaa catttcaatt cacacagcta aaccaggtat
    31741 ggttattggt aaaggcggtt ctgaagtcga aagcctaaga aaagaattaa acaaattaac
    31801 tggtaaaaga atccatatca atatcgtgga aatcaaaaaa ccagatctag atgcaaaatt
    31861 agtaggtgaa ggaatcgcac gtcaattaga aaaccgtgtt gctttccgtc gcgctcaaaa
    31921 acaagccatc caacgctcaa tgcgtgctgg cgctcaaggg atcaaaactc aagtatctgg
    31981 tcgtctaaac ggagcagata tcgctcgttc agaaggatac tcagaaggaa ctgttcctct
    32041 tcatacttta cgtgcggaca ttgattacgc atgggaagaa gcagatacaa catacggaaa
    32101 actaggagtt aaagtgtgga tctatcgtgg agaaattctt ccaactaaaa aaaacactga
    32161 gaaaggaggg aaataatcat gttagtacct aaacgtgtaa aacaccgtcg tgaattccgc
    32221 ggaaaaatgc gcggggaagc taaaggcgga aaagaagtag cattcggtga atacggtttg
    32281 caagctgttg attcacattg gatcacaaac cgccaaatcg aagctgctcg tatcgcaatg
    32341 actcgttaca tgaaacgtgg tgggaaagta tggattaaaa ttttccctca caaatcttat
    32401 actgccaaag caattggggt acgtatgggt tctggtaaag gggcacctga aggatgggtt
    32461 gcaccagtaa aacgtggtaa aatcatgttt gaaatcgcag gcgttcctga agaagtagct
    32521 cgtgaagcgt tacgtctagc ttctcacaaa ttaccaatga aaactaagat cgtaaaacgt
    32581 gaggaaatgg gtggtgaatc gaatgaaggt taaagaaatc agagaattaa ccactgccga
    32641 aatgcttgat caagaaaaac aattaaaaga agaattgttt aatcttagat tccaattagc
    32701 aacaggtcaa ttagaaaaca ctgcacgtat taaagaagta cgtaaatcga ttgcacgcat
    32761 caaaactgtg ttgcgtgaac aagctaagta attatggaag gaggccatta agcgtatgac
    32821 tgaaggaaga aatcaacgca aagtttatca aggtcgcgtg gtttcagaca aaatggataa
    32881 aacaattacc gttgctgtcg aaacaaagaa aaaccaccct atctatggca aacgcatgaa
    32941 ctattctaag aaatacaaag tgcatgatga aaacaacaca gcaaaagttg gcgacatcgt
    33001 gagaattatg gaaactcgtc cattatcagc tacaaaacgt ttccgtttgt tggaagtagt
    33061 cgaagaagca gttattatct aataacacga gattttccta tatagattga atgcaaaatc
    33121 tgaaaggagg atacacaacg tgatccaagc agaaagtcgt ttaaaagtcg ctgataactc
    33181 aggcgcacgt gaaattttga cgatcaaagt ccttggtgga tctggtcgta aaactgctaa
    33241 catcggtgat gtgatcgttg ctacggttaa acaagcaacg ccaggtgggg ttgtcaaaaa
    33301 aggtgacgtc gttaaagccg ttatcgttcg aacaaaatca ggagctcgtc gtacagacgg
    33361 ttcatatatt aaatttgatg aaaatgctgc agtgattatt cgtgatgata aaagccctcg
    33421 tggaacacgt atctttgggc cagttgcacg tgaactacgt gaaaacaact tcatgaagat
    33481 cgtttcacta gcaccagaag ttttataatc ttgagacact tatcaaagga ggtgcgaaac
    33541 agttatgttt gttaaaaaag gcgataaagt taaagttatc actggaaaag acaaaaacaa
    33601 agaaggcgtt gtactagcag cgttcccgaa aaaagataaa gttattgtcg aaggtgtaaa
    33661 tgtcgttaaa aaacaccaaa aaccttctca agctgctcct caaggtggaa ttgttgagat
    33721 ggaagcgcca attcatgttt ctaacgtgat ggtggttgac tctactggtg tagctggccg
    33781 agttggctac aaagaagtag acggcaaaaa agtccgtgtt tctaaaaaaa ccggtgaagt
    33841 tttagataaa taaaagttta aggaaggagg gtcttactga atgaaccgcc taaaagaaaa
    33901 atatcttaaa gaagtaactc catcattgat ggaaaaattt aactatagct ctgttatgca
    33961 aacacctaaa gttgaaaaaa tcgtcatcaa catgggtgtt ggtgatgcgg tatcaaacgc
    34021 taaaaactta gataaagcag ttgaagaatt aactttgatc actggtcaaa aaccaatgat
    34081 tacaaaagct aaaaaatcaa tcgctggatt ccgtttacgt gaaggaatgc caattggtgc
    34141 aaaagttaca ttgcgcggag aaagaatgta cgaattctta gacaaattgg tttctgtttc
    34201 actaccacgt gtacgtgact tccatggtgt aagtaaaaaa gcctttgacg gtcgtggaaa
    34261 ctatacttta ggtattaaag aacaattgat cttcccagaa gtagattatg atttagtaga
    34321 taaagtacgt ggtatggaca tcgttattgt aacaacagca aactctgatg aagaatctcg
    34381 tgagttgttg acacaattag gcatgccatt ccaaaaataa ttaaaggagg cgaactacgt
    34441 ggctaaaaaa tcaatgattg ctaaaaacaa acgtcctgca aaattttcaa cacaagctta
    34501 tactcgttgc gaacgttgcg gacgtccaca ttcagtttat cgtaagttcc atctttgccg
    34561 tatttgcttc cgcgaacttg cctataaagg tcaaattccc ggcgtgaaga aagctagctg
    34621 gtaaaaagta aattcgcata agaaggaggt aaaagatcaa tggtcatgac agatccaatt
    34681 gcagattttc taactcgtat ccgtaacgca aacatggtta aacatgagtc tttagaagta
    34741 cctgcatcaa aaattaaacg tgacatcgct gaaatcttga aacgtgaagg tttcgttcgt
    34801 gatgttgaat acatcgaaga tgacaaacaa ggcgtgatcc gtgttttcct aaaatttggt
    34861 aaaaacggcg aacgtgttat cacaaactta aaacgtatct ctaaaccagg tttgcgtgct
    34921 tatgtcaaag ctgacgaagt accaaaagta ttgaacggtt taggtatcgc aatcatttcg
    34981 acttctgaag gtgttgtcac tgataaagaa gctcgtgaaa aaaatatcgg cggcgaagtt
    35041 atcgcttacg tatggtaatc aagtagaatc tacaaggagg tgtctttaag tgagccgtat
    35101 cggaaataaa gtcgttgtta tccctgaagg agtaacagtt actcaagacg gaaacaacgt
    35161 tacagttaaa ggaccaaaag gtgaattgac tcgtactttt tcagcagata tcaaaatgaa
    35221 tatcgaagga aacgaagtaa ctttcactcg tccaaacgac agtaaagaaa tgaaaacaat
    35281 tcatggaaca actcgtgcga acttcaacaa catggttgta ggtgtcagcg aaggtttcca
    35341 aaaagcgtta gaactaatcg gggttgggta ccgtgcacaa ttacaaggat caaaacttgt
    35401 attgaacgtt ggttactcac atccagtaga aatcacacca ccagctggag taactgttga
    35461 agtaccagct aacacacaag taattgttaa aggtgcgaac aaagaagaag ttggcgaatt
    35521 agctgcaaac attcgtggaa ctcgtcctcc agaaccttat aaaggtaaag gtattcgtta
    35581 tgttggcgaa tatgtacgcc gtaaagaagg taaaactggt aaataatcgt ttagaaaaat
    35641 tgcatagaag ccagcagcag gaaaaaggca tttggctgaa gtttaccttc aaaaaaatac
    35701 atttttactt gtgccgcagc ttctattttt cgaaacgtat ttactgcttg aaatagtagt
    35761 acaataaaaa taaagaggtg acaattgtga ttacaaaacc agataagaac aaaacacgtc
    35821 aaaagagaca tcgtcgtgta cgtaacaata tctctggtac tgctgagcgc ccacgcttga
    35881 acgtttttcg ttctaacaaa aacatctacg ctcaaattat tgatgacgta gcgggtgtaa
    35941 cgctagcaag tgcctctacc ttggataaag aaatttcagg tggaacaaaa acagaagcag
    36001 cacaagctgt cggtaaacta gttgctgaac gtgcagctga aaaaggcatt aaagtagtag
    36061 tctttgaccg tggtggatac ctttaccatg gccgtgtgca agctttagct gaagctgctc
    36121 gcgaaaatgg actagaattt tagaagaagg aggaatacca ttcatggttt atatcgatcc
    36181 aaaacatttg gaattagaag accgcgttgt tgcaattaac cgtgtaacaa aagttgttaa
    36241 aggtggacgt cgtctacgtt ttgctgcttt agttgttgtc ggtgacaaaa acggacacgt
    36301 agggtttggt acaggtaaag ctcaagaagt tcctgaagca atccgtaaag caattgaaga
    36361 tgcgaagaaa aacttagttg aagtacctat ggttggttca acaatcccac acgaagtaat
    36421 cggtgctttt agtggtggta gaatcctaat gaaacctgct gtagaaggtt ctggggttgc
    36481 tgctggtgga ccagttcgtg ccgtattaga attagctggg gtagcagata tcacttctaa
    36541 atctttaggc tcaaatacac caatcaacgt tgttcgcgca acagttgaag gtttgaaaca
    36601 attgaaacgt gcagaagaag ttgcagaact tcgcggcaaa tcagttgaag aattaatcgg
    36661 ataaggagga caacaataat ggctgaatta aaagttactt taaaacgcag tattatcgga
    36721 cgtcctcaaa accaacgcga tacagttaaa gcgttaggtc ttacaaagat taacagttca
    36781 gtggttaagc cttctaatga agcaattaaa ggcatgatca atactgtttc tcacctagtg
    36841 gacgttgaag aaatttaatt tagaaaaatc ataactagaa cattaaggag gtgccaaacc
    36901 tatgaaactt catgaattaa aacctgctga aggttcacgc caagtacgta accgtgttgg
    36961 tcgtggtact tcatctggta acggaaaaac tgccggacgc ggacaaaaag gacaaaaagc
    37021 tcgttcaggc ggcggtgtgc gtttaggatt tgaaggggga caaacaccat tgttccgtcg
    37081 tttaccaaaa cgaggattca caaacgtgaa ccgtaaagac tatgcagtca ttaatcttga
    37141 tgtattgaac cgctttgaag acggagctga agtaactcct gttgctttag ttgaagctgg
    37201 aatcgtgaaa aacgaaaaag ctggaatcaa agtattagct aatggggaac taaacaagaa
    37261 attaactgtg aaagcagcaa aattctctaa agcagctcaa gaagcaattg aagcggctgg
    37321 tggatcaatc gaggtgatct aatgtttaga ctattaaaag atgcttttaa agtaaaagac
    37381 attagatcga aaatcctatt tactgtattt gtgttgtttg tatttcgcct aggtgcacat
    37441 attactgtac caggcgtaaa tgctgcttca ttgcaaaacc tttcttcttt gccatttttc
    37501 aacatgttga acttggtaag tggtagtgcg atgcaaaact tttccatttt ctcaatgggg
    37561 gtttcaccat acattactgc ttctatcgtc attcagcttc ttcaaatgga catcgtgcct
    37621 cgatttgttg aatggtcgaa acaaggggaa gttggtcgta aaaaactgaa tcaagcgact
    37681 cgatatctga cattagtatt ggcatttatc caatctgtcg gtatcactgc tggattcaat
    37741 caatacgctc aattaggttt cgtgaataat cctaacgtag caacttacgt aacgatcggt
    37801 ttgattctaa cagccggtac gatgtttgtt acttggctag gagaacagat cacagaaaaa
    37861 ggtatcggaa atggcgtatc aatgatcatt tttgcaggta tcatttctag attgcctgaa
    37921 agtatcagag aaatttatga agattacttt ataaatattg atccttcaga catatggaaa
    37981 tctgctattt ttgtggccat tttactagta gcggtcttgt tgatcgtgac attcgtaaca
    38041 tttttccaac aagctgaacg caagatcccg atccaatata cgaaacgcgt agctggcgcg
    38101 cctacaagca gctatctgcc gttgaaagta aatgcagctg gagttattcc agttatcttt
    38161 gctagttcgt ttattgctac gccaaatgct gttttacaag cattgagcgg tagattcggt
    38221 tctgaaaact ggtacaaagt gatgatggag atctttaact ataatacagc acctggtgct
    38281 acgatttata cgattctgat cgttgccttc actttcttct acgcctttgt tcaagtaaac
    38341 cctgagaaat tagcggaaaa cttgcaaaag caaggaagtt atataccaag cgtacgccct
    38401 ggtaagggga ctgaagagta tgtctcaaga ttactgatgc gtttaagtac agttggtgca
    38461 gtcttccttg gtttagtggc attgcttcca atcattgctc aaatggtttg ggatcttcca
    38521 caatcaatcg gattaggcgg tacaagctta ctgatcgtta tcggtgtagc tttagaaact
    38581 gcgaaacagt tagaaggctt aatgctgaaa cgtaaatatg ttggattcat tgagtaagaa
    38641 agcgtgttga ggtttcccct caacacacgt tctcacacat ttattaggag ggaaaacaat
    38701 gaacctcatt ttaatggggc tgccaggcgc aggtaaagga acacaagctg aaaaaatcat
    38761 tgatgcttat ggtattccgc acatctcaac aggagatatg ttccgcgcag cgatgcaaaa
    38821 cgaaacagct cttggcctgg aagcaaagtc ttatatggat aaaggtgcat tagttcctga
    38881 tgaagtaaca aatggaatcg tgaaagagcg actagctgaa ccagatacag agaaaggctt
    38941 cttattagat ggctttccac gtacgctaga tcaagcaaaa gctctggacg caatgctaaa
    39001 agatttgaat aaaaaaattg atgctgtcat cgatatccat gttggtgaag aaatcttggt
    39061 cgaacgtcta gccggccgat ttatctgcag caattgtgga gcaacttacc ataaaatttt
    39121 caaccctaca aaagttgaag acacatgtga tcgttgcggt gggcatgaat tctatcaaag
    39181 agaagatgat aaacctgaga cggttaaaaa tcgtctggct atcaacatca aaaatagtga
    39241 accaatcttg gcttattata aagaacaagg tttgctaaac actattgatg gtgctcgtga
    39301 aatcgatgct gtatttgcag atgtacaaaa aatcattgaa aaatagcacg attgcccgta
    39361 gccgacttgc attatgcagt tactcttgtc aagttcaata aattatgata gaatatgtca
    39421 gtccgacttc tagagaatcc tctagatgat ccattttgag aattttgagg tgggaactgc
    39481 agtttccgcc attttatcgt gtgaaaatgc gaaacaagta caaggaggta ctgtgcgtgg
    39541 caaaagaaga tatgattgaa gtcgaaggta cagtcgtcga aactttgccg aatgcaatgt
    39601 ttaaagttga actagaaaac ggacaccaag ttcttgctac tgtttcaggt aaaattcgta
    39661 tgcattacat ccgtatctta cctggtgaca aagtaacggt tgaattgtct ccatacgatc
    39721 ttaaccgtgg ccgtattact tatcgcttta aataattgta ctccgtaaaa ctacaggagg
    39781 tattatcatg aaagtaagac catcagtaaa accaatgtgc gaacattgta aagtaattcg
    39841 tcgtaaagga cgcgttatgg tgatttgccc agcaaatcca aaacataaac aacgtcaagg
    39901 ataattggag gtgctataaa tatggctcgt attgcaggag tagatattcc tcgtgataaa
    39961 cgtgtagtag tttcacttac ttatatctat ggtattggta acactactgc taaaaagatc
    40021 ttagctgatg ctggtgtatc tgaagatgtt cgcgttcgtg aattaacgaa tgaacaaaca
    40081 gatgctatcc gtgcagaagt agataaatta aaagttgaag gggatcttcg tcgtgaagtg
    40141 aacttgaaca tcaaacgttt gatggaaatc ggttcttacc gtggaatccg tcatcgccgt
    40201 ggattgcctg ttcgtggaca aaacacgaaa aacaatgcac gtactcgtaa aggcccagct
    40261 cgcgctatcg ctggcaagaa aaaataattc ttaagtgaag gaggttaaaa cttcatggca
    40321 gcaaaaaaag tgaatcgtaa acgccgtgtg aagaagaata tagaagcagg tattgcacat
    40381 atccattcta cattcaataa cactatcatc atgatcactg atactcacgg aaatgcatta
    40441 gcgtggtcat cagctggttc attaggtttc aaaggaagca aaaaatcaac tccttttgcc
    40501 gctcaaatgg cagcagaaac tgctacaaaa gcagcaatgg aacacggatt aaagactgtt
    40561 gaagtaacag ttaaaggacc tggttctgga cgtgaagcag caattcgttc attacaagct
    40621 acaggtttag aagtgactgc aattcgtgac gtgactccag ttcctcataa tggtgcccgc
    40681 cctccaaaac gccgtcgtgt ttaatgagtg ccgctcattt tgagttttat cagtaacgtc
    40741 attgaacaag acacttttcg ttttgaaagg ggtaaagata agaatgattg agttcgaaaa
    40801 accaagaatc gcaaaaattg atgaagaaaa agattatggc aagttcatcg ttgaacctct
    40861 tgaaagaggg tatgggacta ctttagggaa ttccctacgt cgtattttat tatcttcttt
    40921 gccaggtgct gccatcacta atattcaaat cgatggtgta ctgcatgaat tctctaccat
    40981 caaaggtgtt agagaagacg tcactcaaat catcttgaac attaaaggct tagcgctgaa
    41041 aatgtatggc caagaagaaa aaacccttga aatcgatatt accggacctg ctacagtaac
    41101 tgctggcgat attatcgttg atagtgatgt agaaattctt aacaaagata tgtacatctg
    41161 tagtgtctct gaaggagcta cgttccatgc tcgcttaaca gtgaaacctg gacgtggtta
    41221 tgttcaagca gatgaaaata aaaaagaaga tatgccaatt ggcgttcttc cagtcgattc
    41281 aatctacaca cctgttcgtc gtgtgaacta tcaagttgag aacacacgtg ttggacaccg
    41341 tgaagatttt gataaattga cgatggagat ttggacagat ggttcaattg aaccgttgga
    41401 agcaatgagt ttgtctgcga aaatcatgac tgaacatttg gatatttttg tgaacttaac
    41461 tgatgaagca aaaaatgctg aaatcatggt cgaaaaagaa gaaacacaaa aagaaaaaat
    41521 gttggaaatg acgatcgaag agttagactt gtctgttcgc tcttacaatt gtttgaaacg
    41581 tgcaggaatc aatactgtac aagaacttac aaataaatct gagcctgaaa tgatcaaagt
    41641 ccgtaactta ggacgtaaat cattagaaga agttaaagca aaattgcacg acttaggttt
    41701 aggtttacgt aaagaagatt aaaacctttt acgaaggagg gaaaccaacg tgagttatcg
    41761 taaactagga cgcacatcta gccaacgtaa agcgatgttg cgtgatttaa caactgattt
    41821 attaatcaac gaacgtattg tgactactga agctcgtgcg aaagaagttc gctcaactgc
    41881 agaaaaaatg atcactttag gtaaacgcgg agatttgcat gcacgtcgtc aagctgcggc
    41941 tttcgtacgt aatgaagttg ccagcgtgcg tgaagaaaat gaggacatcg tcattgaatc
    42001 agctttacaa aaactgttca acgatattgc acctcgttac gcagaacgtc aaggcggata
    42061 cacacgcatt ttgaagacag aaccaagacg cggtgatggt gcaccaatgg ttgtcttaga
    42121 acttgtctaa aatcacacta ataacatcac tttatagatg attcttttag agtgttatga
    42181 tgttggaaga tatttttccg agtctagctc agcgctgctc ctcaagcgaa tatcgcttgg
    42241 ggagtaagca ctcatcataa agtgtttttt tataccttca attacctgtc atgacagata
    42301 tgtttgaagg cataaaaaaa cattttaagc gagaaataat tgaaaatttt gtcttttttt
    42361 gatagtgtta gtaggaactt taggatgaag aaggagtaat catggagcca attattgaat
    42421 tagaaaagat aaattataaa taccagccag atgatcttcg ccccgcattg aaagatgtct
    42481 cctttacaat tgataaaggt gagtggatcg ctattattgg acacaatggt tcaggaaaat
    42541 cgacacttgc caaaacgatc aatggattgc ttctgccaga atcagggatc gtgaaagtgg
    42601 gaaatcaaat attggatgaa gaaaatattt ggacgatccg acagatggtt ggaatgattt
    42661 ttcaaaatcc agacaatcag tttgttggtt cgacagtaga agatgacgtt gcttttggtc
    42721 ttgaaaatca agggattccc agagaagaaa tgctagtgcg tgtgaaagat gcacttgaga
    42781 aagttagaat ggctgagttt gcttcacgcg agcctgctcg tttatcagga gggcaaaaac
    42841 aacgtgttgc cattgccggc gtggttgcct tacgacctga tatcattatt ttagatgaag
    42901 caaccagtat gctagatcca gaaggtcgtg aagaagtgat ctctacgatc aagaagatca
    42961 aagaagaaag tcaattgacc gttatatcta tcactcatga tattgatgaa gcagctaatg
    43021 ccaatcggat actagtgatg agacaaggcg aacttgtccg tgaaggtaca ccaaaagaaa
    43081 ttttttctgc tggtcctgaa ctgatcgact taggtctaga tctaccattt cctgaaaaac
    43141 tgaagagcgc actgaaagaa cgtggggttg atgtgcccag tgaatatatg acagaagaaa
    43201 ggatggtgga ttggttatgg acatccgttt tgaacaagta gacttcactt atcagccgaa
    43261 tacaccattt gaacaaagag ccttatttga catcaatatg acgatcaaag aaaacagtta
    43321 tactgcatta gtagggcata ccggaagcgg gaaatcaacc ttacttcagc atttgaatgc
    43381 gcttgttaag ccaacaagcg gtacagtcca tattggagaa cgagatattc agccggatac
    43441 ggataataag aatttaaagc ccatccgaaa aaaagttggc atcgtctttc agtttccaga
    43501 agcacagcta ttcgaagaaa cggtagcaaa agacattgct ttcggtccta aaaactttgg
    43561 tgtcagcgaa gaagaagcac tagtcctagc aaaagaaaca ttagaacaag ttgggctgga
    43621 tgaaagctat ttggaacgtt cgccatttga actttcagga gggcaaatgc gtagagtagc
    43681 aatcgctggt gtgcttgcca tgaggccgga agtacttgta ttggatgaac caacggcagg
    43741 acttgatccc cagggcagaa aagaaatgat ggagatgttt tggcgtcttc ataaggaaca
    43801 gcagatcact attgtattag ttacgcattt aatggatgat gtagccaatt ttgcagatta
    43861 tgtctatgtg ttggaaaagg gacgaatcgt taatagcggg gagccgcaag aggtctttca
    43921 aaacattgaa tggctaaaag aaaaacaact aggcgtacct actgccaccg agtttgcaga
    43981 agaattaatg gctaaaggga tgaactttgc taccttgcct ttgacagctg aagaattagc
    44041 agacgctatc gtccattatg ctggaggaaa tgcccatgat gaataaattg atatttggtc
    44101 gttatatgcc tggagattcc ttgatccatc gattggatcc ccgagctaaa ttattagcca
    44161 gtttttattt tatcggaatc atttttttag caaataattg ggaaacgtac cttttgttgg
    44221 catttttcac attactttct gtcttcttgt caaaagtaga tttgaaattt tttatccgag
    44281 gcattcgccc attgatctgg ctaatcctct tcactgtagc tttgcaggtc ttgtttacaa
    44341 gtggcggaga aacttattgg agttggggtg ttttccatat cactgaattt ggtgtgatga
    44401 acggcctctt tattttctgt cgattcgtgt tgatcatttt tatgtcgact ctactcacgc
    44461 ttactacacc gcctttggaa ttatcggatg cgattgagta cttgcttcgt ccattgaaag
    44521 ccgtacggtt cccagtccac gaaatttcat tgatgctgtc gattgctctt cgttttgtgc
    44581 ctacattgat ggacgaaaca gaaaagatca tgaacgctca gcgcgctcgc ggtgttgatt
    44641 ttggtgaagg aaacctagtt cagaaaatga aagcagtcat tcctttgctg attcctttat
    44701 ttgtcagcag cttcaaccgt gcggaagatc ttgcgactgc tatggaagca agaggctaca
    44761 aaggtgggga aggaagaacg aaatatcgtg tattgcattg gcataataga gacacgatgg
    44821 ttatcattgc ttttgtatta ttaactgtgc tactgatctt tttaagagga taaacgttca
    44881 gtgggccgct atctattctt ttcttgctga tctgtttgca agaaaggatg caagcagtgt
    44941 atgacaagaa atattagggt ctgtggcaga ctaaggtcac aggcctcttt cttttatctg
    45001 aaaagaaaga acgaaaaaat tttatagaaa aatcattatt ccagataacc ttttaggaac
    45061 aaaggagaga aaaacatggt acgttacaaa gcaatcattg cgtacgacgg aacaaatttt
    45121 aatggattcc aaaaacagcc aaatgggcgt actgttcaag aagaagtaga aaaaacatta
    45181 caaaaaatgg caaatggaaa agaaatcacg gtctttggtt cgggaaggac agatgccgga
    45241 gtacatgcga tcgggcaagt aatccatttt gattatccag aggagcgtcc gttagaacga
    45301 atgcgtttcg cgctagatac ccagtcacca gaggatattg ctgtaagaca agtagaaatt
    45361 gtttcagaag acttccacgc aagatatttg gtcaaagaaa agacgtatca atttcgagtg
    45421 gatataggga aaccacgcag tccttttcga cgccattatg caagttattt tccttaccca
    45481 cttgatttgg aaaaaattca gcgggcgctt cctgatttat tagggactca cgatttcacc
    45541 tctttttgtg catcaggaag ctcgatagag gataaaatac gtacgatcta cgaggctaag
    45601 atggaggtaa atgaaacaaa agacgaattg ttgtttacat ttaggggaaa tggcttcttg
    45661 tataagatga tacggatctt agtaggaacg cttttgaaaa ttggcaatgg ccgattgcct
    45721 gaagatagta tcccagatat tattgcgaaa aaagatcgta atgcagcagg acctacagca
    45781 caccctgaag gactttattt gtatgaagtg aaatatgaat aagaggttat gatagaagtg
    45841 gtcagcttca agaaataaga aggtatttac gaaaattact tctcaaaatt ttgcaaaatt
    45901 tcggcttatt ttcgaagaag ctacttctgg aacaccgttt aagaaagagg tcgtgagcct
    45961 gtcatttaac tctgagtcac aaagagcaat ttcaaaaaac agcttctcat ctttgatgaa
    46021 tatcgtgact tgtggacgag gcgttgataa gtgaatcatc tttttgttac ctattttttc
    46081 tgtaaccaaa aaacgatgga acgttgtttt gattgccctt ggtgcggaca gtctgaacag
    46141 gttccatcgt ttctttattt tctacgtctt cttctgtgtg tgtttcgtgg ttgttcttct
    46201 attgctggat caatcgtgcc ataaaagggg cgattgcggt caaggtacca gacataaaga
    46261 ataaacaatg caatacatag gacaaaaagg attgcaccta tcgtaaatcc ttcaggcaag
    46321 taactgaaag tgacagtatg tttacctgct ggaactttta tcatcaagaa tgcgtctttg
    46381 aaattgctga ccttgactgg tttcccatca attttagctt tccatccttt gtcataagga
    46441 atagttgtca ccaacatgga atcttcagcg gtatttacag tcccagaagc ttttctgcca
    46501 gtggcttcca tttcgacacc tttttctttg atctgattca ttgcggcttg ataggctaca
    46561 acatctagac caacgacttt aggctccatg aaacttattt ctttcgtccc ataaaaactt
    46621 gcagtaaatg tcactgttgt ctcttgagga taatagccaa gatcatagta ttgaccagaa
    46681 atgttgattt gcgtttttcg cgatgtacca ttgacagtga tcgtcgcact agaactttct
    46741 aattgcgcaa aattggttgg gaacaaactt aagtaagctt gtgtatttgc aggcacatgg
    46801 acttcccaag tgagctcttt tggctggtta tctgctgttt ctgagtaagt gacgccagtc
    46861 gttgtctttg tgatcgtcgt attcaactga ttcttcaaag taggtgtata gaatgtaaaa
    46921 tactgttcat ttagaccaga caatgtattg atcaagtttg tctgactggt caaattatct
    46981 gtcactggct gctcaacatc attaacggac aacggtgcag taaatgctag tggcaatgca
    47041 ttgacattct gatacagtgt atagtcgccg ctttgaccag cttggcggaa gccatattta
    47101 ctgaacgtgc tttcgttttt agaaatgtta tatttgattc ctgtaaaccc atccatcagc
    47161 aaagtattat tgttataacg gatattcaaa tttgtccctc ttgaacggaa acctaattta
    47221 tccaggtaag aggaagaatt acgatttctt atagaagaaa acaaactgat accactgtaa
    47281 ccatagttga tcgaatcgtt tgcagatact ggatccagat tttccaagcg gtaaaacgag
    47341 tcggaatctt tttttgtttc atttacaaga gctttcaagt caggataagg atcagtatat
    47401 aaactgcggg aagcataatt ccaatcatca agaatgccat ggatcatact gttcgtattg
    47461 accagtgctt cagcagacat gatcaataat aacaatatac tcagatgatt gaatgaaagt
    47521 tttttatgct gataaaatcc cacagcaaaa gcataaatcc ctaagaaaac cactgtcaat
    47581 acaaaggaag tcatcgtcac ataggtgtag cttccttcag gtttgatgcc ccatgccacc
    47641 gcaaagagag cagctacgac caaaatgatt cctaacaaca gcccaccatc gtcttgttct
    47701 atcttttccc atccttttcc tgcaagcagg agcactaaga aagagaacag ataggcataa
    47761 cggaataaaa acatattcgg tgcatgcata ccatgccaga acaaattcaa tggaacaaga
    47821 taaaaacttg cgataagtat ggcgaaaaga ctgccgtaca aaaatttatt tttcaacggt
    47881 actttccgac tggcaaaata aaacagacag aggactaatg gtagcagacc tgcgtaaacg
    47941 aacggaatcg atccgtattt tgtcgtgtca taaacaccaa tcatattttt catgattaga
    48001 tccagataag aagtcgcttc tgttttcaac gtagtgatct gactcagtgc ctcgccattt
    48061 gaccgaagat ccagcactgc tggcaataca atgatcattg aagcgccgcc tgccagtaaa
    48121 gaagtgatac cataaggaac aatcgttttt ttatattctg accagtttgt caatagacgg
    48181 gcgataaaat ataagaaaga aaatacgcca atcataaaac ccatataaaa actggataaa
    48241 aacaagagta aataactgat aaataaaagt ttcggccgtt taagatccat aacacgatga
    48301 atccccaaaa tcactaatgg aagataaaca aatgcatcca gccacatgat gatctccgaa
    48361 tgtgcagtga taaatgagat caatgcgtaa ctgacgctaa gtgcaacatg cccccagcga
    48421 ggaatcttga acgtacgtgc aagaaaccaa aaagccaatc cggcacagcc gaccttaagc
    48481 aaagtcagaa catacagtgc atctggcatc atctggtttg gaaaaaagaa caccagtggc
    48541 gtgaagatcc cgcctagata gtaagaaatt aaagataaat aattcaatcc tagagaagca
    48601 ttccatgtat aaaaaatact ttgctttcca agaagaacat ttcggaagct ggcatgaaaa
    48661 ttagaaaact gtgaaaaggc atcacttgcc aaaatacttc tgctgcttcc aggatagatt
    48721 ccgatactta gataaacaag tgctaaaatc aaaaacggaa tcaggaaact agctgctgcg
    48781 tagcgtccgt tttctctaaa gaatgacttt aaattttttt tcatatttat tttccaccaa
    48841 atttctatga agttgtattc agtttatcat atccttgttt ttctctgctt aaaaagagtc
    48901 tagttttcac aaaaaaataa aatttagaat aaataacttc ataatttgtt cgtataacaa
    48961 aaataaacgc aaaaaaaggg taggaatcaa aagtcccacc cttaaaaatt tttattaaat
    49021 aaaaaaccgt tcactatctg aacggtccaa gtatcattca attaaacgcg ttcaactttt
    49081 cctgatttca aagcacgagt tgacacccaa acttttttag gttttccgtc gaccataacg
    49141 cgaacttttt gtaagttagg tttaacagta cgttttgttg agttcatagc gtgtgaacgg
    49201 ttgtttccac tttttgtctt gcgacctgta aagtaacaaa cttttgccat ggtaatttcc
    49261 tcctttgcct tgatttggag caatagaata attcagctca taccagacta acatatcata
    49321 tagaatggga atttgcaagt acattttcat agatacaatt gacaattgag aagaataatt
    49381 gtaaattaaa caaggttata cctgaaattt tgcaaggttt ttgagtactt tgggtaactg
    49441 ccttttattt caagttgcgc tatgataaaa tatgatagaa gaaaaatggg agttttttac
    49501 ccgttaagga ggctcattca tggctgtaaa aattcaaacg tcagctggaa ccattgaaat
    49561 taccaatgat gtaattgcaa cagttgttgg tggcgccgcg acagatgtgt tcggtgttgt
    49621 aggaatggcc agcaaaaatc aaattaaaga taatattact gagattttgc gtaaagaaaa
    49681 ttactcaaga ggagtagttg tccgccaaga agataatggt attgctgtag atgtttatac
    49741 gattatcagc tatggtacga aaatctctga agtttcccgc aacgtccaag aaaaagtgaa
    49801 atacaatcta gaggcattat taggcgtaac tgccaattca gttaatgtct ttgtacaagg
    49861 tgttcgtgta ctgccagact aggcaggaga ctggctggta actcagcagt cgatctgaag
    49921 gaggattatc taggtgagtg taacagaaat aagtgcaagc cagttccagg aaatggtcca
    49981 ggcaggtgcg aatcgtctgc aagtaaatgc agaatacgtc aattcattaa atgtattccc
    50041 tgtgccagat ggcgatacgg gaacaaatat gaatctatct atgactagtg gagctaaggc
    50101 agtagtagat tcaacctcag aaaaagtagg agaattagca gcaatgcttt caaaaggatt
    50161 gctgatgggt gcgcgcggaa attccggcgt tattttgtct caattgtttc gtggattttc
    50221 taagcaaatt ccagatgttg tctcattaaa tgcttctgat cttgctgcag ccttcactca
    50281 tggagttgaa actgcgtata aagcagtaat gaaaccagta gaaggaacga ttttgacagt
    50341 agctagagaa gcagcgaaag ctggagaaaa gaaagcaaaa agtactgatg atgtcgttga
    50401 agtaatgaca gctgttgtaa aaggagcaaa gcgtgcttta gctaaaactc cagacttgct
    50461 tccagtccta aaagaagtcg gtgtcgtaga cagtggaggg caaggactgc tgtttgttta
    50521 tgagggcttt ttaagtgcat tgaatggaga attccaagcg gatgaaacat atgaaccttc
    50581 tccagcagaa atggatgata tggtcaatgc agaacatcat cgcagtgtcc aaggtcaaat
    50641 ggcgacagaa gatatccatt ttggttactg tacagaaatc atggtaaaaa tcggagaagg
    50701 acctacagtc gatagtacat tcgattacga agaattccgt aactatttag atggtatagg
    50761 agattcttta cttgtggtca atgatgacga gatcatcaaa gtccacgtgc atacagaaaa
    50821 cccaggagaa gtcttgaatt atggacaaaa attcggttca ttagtcaaaa tcaaagtcga
    50881 caacatgcgc ttgcagcatg agacgatttt ggaacacgat gaagaagtga acgagtttgc
    50941 gaaaaaagaa ataccacgta tcccgtatgg tatcgtagcg atcgctgctg gtaaaggcgt
    51001 ccaagagctg tttgaaagtt taggcgctaa ttatgttatc agtggtggac aaacaatgaa
    51061 tccaagtacg gaagacattg ttaaagcgat tcaagaagta aacgcagata aagtgattgt
    51121 cttgccaaac aataagaaca tcttcatggc agctgatcaa gcagcagaag tagcagatat
    51181 cccagtagca gttgttcctt caagaacgat ttcccaagga ttgacagcta tgctttcatt
    51241 caatgatcaa gcttctttag aagaaaacaa agaaacgatg acagaaatgt tgtctagcgt
    51301 tgtgagcggt caagtcactc acgcgatcag agatacctca attgacggtg tagagatcaa
    51361 agaaggagac tttttgggca tgatcgatgg aaaaatcctg atctctaacc cagatatcac
    51421 agcaacagcg ttaagtacac tagaacaaat gatcaatgag gacacagaga tcgtaacgat
    51481 cttggcaggt gatgaaggaa cagttgaaca agcaaatgaa tttgctgaga aactaacaga
    51541 aaaacatcct gatttggaaa tcgagatcca ccaaggagat cagcctgtct atccttatct
    51601 attttctgct gaataatttc tgtgtcagaa tatctttcta acacagtatt cattcataaa
    51661 aggccttcgg ttagtgatca ggtatgatcg ctgaccaagt cctttttttg ttaaaggagg
    51721 gaggaaaaat ttatgcgttc tttagatgat ccaatcacta tgctggcagg agtcggagaa
    51781 aaaagagcag ctagtcttgc cagcttgggc atccaaacga ttgaagactt actgacttat
    51841 tatccttttc gctacgaaga tattcaggaa agaaatctaa acgagatcca ggatcaagaa
    51901 aaggttactt tgaaaggaat cgtagtctcg cctcctgtga tgaatcgatt tggttataaa
    51961 aaaagccgat tgcaatttcg tatgatgcaa gaacatgatg tgttcaacgt ttcttttttt
    52021 aatcaacctt atctaaaaga aaaagtcatt ttatcggagg aaatcgccgt atacggtaaa
    52081 tgggatgcaa agcgtaaagc cttgaacggg atgaagattt taggttctca aacaatggat
    52141 gacttttcgc cgatatatca cgtcaacaaa tcaattcgtc aaacgacatt agttgatcta
    52201 atcaaaaaag ggtttcaaga atacggcaca ttgattgaag aaaatctgcc aaacaacctt
    52261 gtggagaaat atcgactgct tgaccgagct tctgctgtaa gaagtatgca ttttccaaaa
    52321 gaccacgaag aaaaccatca agccaaacga cgtgtcgttt ttgaagagtt ctttttattt
    52381 caaatgcgtc ttcaaggatt gaaaaaagca gaaaaagcag aaacgaatgg tttggagatc
    52441 ctttatgatg tccaaaaatt gaaacaattt actcaaaagc taccttttga actgacaaat
    52501 gcacaaaaac gtgtaacgaa tgaaatctgt cgggatcttc gcagtccgca gcatatgcag
    52561 cgacttttgc agggagatgt aggtagcgga aaaacagtgg ttgccgcgat tgcgttatac
    52621 gctaccgtta cagcaggttt ccaaggtgcg ttgatggtgc ctacagaaat cttggcacaa
    52681 caacatatgg aaagcttgca acagctgttt gatcccaatg aagtaaccat cgcattgatt
    52741 acggggtcaa cgaaagcaaa agaacgacgt gagctccttg aaaaactaga gcaaggggaa
    52801 attaacgtcg tgatcggcac acatgcattg atccaagatg gagtcgaatt tcagaattta
    52861 ggtctagtta ttacggatga gcagcaccgt tttggcgtga accagcggaa agtacttcgt
    52921 gaaaaaggct ggcgaccaga tgtcttattt atgacagcga ctccgattcc tagaacatta
    52981 gctattacag catatggtga gatggatgta tctatcattg atgaacttcc agctggacgt
    53041 atcccgatcg aaacacgctg ggtaagaaca cctcaattgg acagtgtact ggattggacg
    53101 aaaaaagaac tggcaagagg acatcaaatg tatgtcatct gtccgctgat tgaagaatca
    53161 gaagcattag atgtaaaaaa tgcagtggaa atctatgaaa aacttcgtga actatttgca
    53221 ccaaaatatg aagttggctt gttacatggt aaaatgaaga atcaggaaaa agaagtaatc
    53281 atggaagcct tcaaagacaa ccagatgcag atattagttt cgactactgt aattgaagta
    53341 ggggtaaacg tgccgaacgc gaccgtcatg ctgatcatgg atgcggatcg atttggattg
    53401 gcacagctgc accaacttcg tggacgtgtt ggacgcggaa gtgatgcttc ctactgtatc
    53461 ttagttgcta atcctaaaaa tgaactaggt gtggaacgga tgaaaatcat gacagagacc
    53521 accaatggtt ttgtactaag cgaaaaagat ctggaattac gtggtcctgg tgaagtattt
    53581 ggcttccgtc aatctggtct gcctcaattt gcgattgctg acttggtgac ggatggaaat
    53641 gttttggagg tagccagaga agaggctgca gccctttggc aaataaagga ttggcagatg
    53701 cttcctgagt atcagccttt agcgcaaagc ctccaaatag aaaatcagga taatcgttat
    53761 ttcgattagc agactgtgct atactttata ctgatgacgg aaaaaggagt ggaaacaatg
    53821 aaaattgccg tagatgcaat gggcggagat cacgcacctc aagcaattgt agaaggcgtg
    53881 gctttagcgc agcaagattt tccagaagta gaattcttac tttacggaaa agaagcagaa
    53941 atcaagaaat acttaacaaa tgaaaaaaac atcacgatta tccatacaga cgaaaaaatc
    54001 aatagtgatg atgagccagt aaaagcaatt cgacgaaaaa agactgcatc aatggtcctt
    54061 gctgcacaag cagtgaaaaa cggtgaagca gatgctgtat tttcagcagg gaatacaggc
    54121 gcgctactag cagcagggtt gttcatcgta ggacgtatca aaaatatcga acgccctggc
    54181 ttgatgtcta ccttgccagt agtagggaaa gaaggtgccg gtttcgatat gctggatctt
    54241 ggcgctaacg cagaaaacaa accagaacat ttgttgcaat acggtatttt aggttctttt
    54301 tatgcacgta aagtccgagg tatcggacgt cctcgtgtcg cactcttaaa caacggaaca
    54361 gaagcaacaa aaggtagtga agtgacgaaa aaagcctatg aactccttca gaatgaaaca
    54421 agcttgaatt ttattggaaa cgtagaagct cgtgagctac tcaatggtgt ggctgatgta
    54481 gtggtcacag atggatttac aggcaacgct gttttgaaat ctattgaagg aacagcaatg
    54541 aatatgatga atctattaaa atctgctatt ctaaatgaag ggatcaaagg aaaaatgggc
    54601 gctatgcttt taaaagacgg cttacgttct ttgaaagcag aaatggatta ttccaaacat
    54661 ggcggtgccg ttttgtttgg cttgaaagca ccagtcatta aaactcatgg agcaacaggc
    54721 cccgatgctg ttcgctatac gatccgccaa atccacacaa tgcttgagac agatgtagtt
    54781 ggacaattag tcgaacaatt tgaaaaaagc gaagaatagt atttggatat ctgaagcgat
    54841 ccgttccatt gaaaaaaagg tggacattcc tgaaaaatgc cagtaaaatt agccatggtg
    54901 taggtaattg acaagtgtat gattcttgga ggtgaaaaag ttgactcgcg aagaagtatt
    54961 taacaaagta gcgaaaatta tttcaaatca ttttgagata gataccgata aagtgacgga
    55021 tgaattgaac atcaaagatg atttaaaagc tgattcaatt agtattatgg aattcgtttt
    55081 agagcttgaa gatgaattcg gtacggaaat ttcagatgaa gacgctgaac aaattgaaac
    55141 agtcggtggc gcagtagatt atatcagcag ccatcttaaa taatttcaaa taaaagcaaa
    55201 gaaggataaa aagctgcatg cagcttttta tccttctttt tttaatcttt ttgacacgta
    55261 aaagtcattt ttctgataat tctggcgata aacagaaatt atgttgcaaa gtaaagcggt
    55321 tttctatata attattaata attcattaca caaagataag aataaccttt gttataaaac
    55381 gatttattct gtgtaatgtc cttttttatt aagaaaaact tccatttagg aagcagagag
    55441 gggtattcga ttgtccgata accaattatt agaagttcag aacctacata caggattccg
    55501 actcaaagat gactattacg atgcagtaga tgacgtttca tttactttag acaaaaacga
    55561 gattttagca atcgttgggg aatctgggtg cgggaaaagt accttggcta ctacgattat
    55621 gggattactt gatcctaata acacaaaaat tacaggtgag attttatata acgatctgaa
    55681 tttaatcgac ctgaacgaaa cgctctataa taaaatccgc ggaaatgata tcggaatgat
    55741 tttccaagat ccgttgtctg cattaaatcc tctcatgaga atcgaagacc agatcaaaga
    55801 aggactttcc tatcacacaa agatgaatgc agaacagcgt caagctcgtg cactagaatt
    55861 gctagaacaa gtagggattc ctaatcctgc gagagttgga cgccaatatc cccatgaact
    55921 atcaggcggt atgagacaac gtgtcatcat cgcaatcgca atcgcctgca aacctccaat
    55981 cgtcattgca gatgaaccga cgacagccct agatgtaacc atccaagcac agattcttga
    56041 tttactgaaa gaccttcagg aagaaacaaa aacagggatc atcttgatca ctcatgactt
    56101 aggagtcgta gcagaaatgg ctgatcgagt ggcagtgatg tatggcggac agttcgttga
    56161 agtagcaggt gtaaaagaac tgtttgatca tcctaagcat ccttatacac gctctttact
    56221 gaactctata ccacaagaag gaaatcatga tgcagaactc catgtgatcg aaggtgtcgt
    56281 tccttctctg aaaaacatgc ctcgtaaagg ttgtcggttt gcaccacgta ttccatggat
    56341 accagcaagc gatcatgaag aagagcctat ccttcatgaa gtcgcaccga accacttggt
    56401 acgttgctcc tgctataagc atttccactt tagagacgaa aaaggagagg tgtagatgac
    56461 agaattaatc acaatcaaag acctgaaagt tcattaccct attcgcagtg gattcttcaa
    56521 tcgagtaacg gatcatgtat atgctgtaga tggtgtggat tttattatcg aaaaaggaaa
    56581 gacatatggt ttagtgggag agtctggctc tggaaaatct actacgggaa aagccgttgt
    56641 gggattagaa aaggtaacag ccggacaaat catgtatgaa ggaaaagatg taacgaagcg
    56701 aagcaaccgc aaaaaaatgg gttataacaa ggatgtgcag atgatcttcc aagattcaat
    56761 gtccagtttg aatcctaaaa agcgagtgtt ggatatcatt gctgaaccca tccgaaattt
    56821 tgaacggtta agcgatcaag aagaaaagaa aaaggtaaaa ggactgctag atatcgttgg
    56881 gatgccggaa gatgcgctat ataaatatcc tcatgaattt tcaggcggac aacgtcaacg
    56941 tctaggagta gcccgtgctg ttgctaccaa tccaaaactg atcgtagccg atgaacctgt
    57001 atctgctctg gatctatctg ttcaagcgca agtattgaat ttcatgaaac gaatccagca
    57061 agaatacggc ctcagctatt tattcatttc acatgattta ggtgtagtaa aacacatgtg
    57121 cgacaatatc gcaattatgt acaaaggtcg atttgtagaa atcggtacaa gagaagacat
    57181 ttataatgac ccgcgacata tctatacgaa acgtctgctt tcagctattc cgcaaatcga
    57241 tgtagaaaat agggaaagcc acaaagaaaa tcgacgaaga gtagaacaag agtatatcca
    57301 aaaccaaaaa gaatactatg atgcgactgg tcgagtctac gatttgcgta cgatcacaac
    57361 tacacacaaa gtggcgttga aagatggagg tgcaagctaa tgtggaaaac gattctgcga
    57421 cgtgttttat tgatgatccc gcaagttatt attttaagtg ttctgatctt cttattagcc
    57481 caagcgatgc cgggggatcc atttaccggt ttgatcaatc caaatcagga tccggcagtg
    57541 atcgaacaga tgcgacaagc agctggcttg aatgacccat ggtatgtcca gtacttccgt
    57601 tggatcggaa atgctttgca aggcgatttt ggtcaaagtt tcttatacaa acgctctgtt
    57661 gctgacttga tcggcgaacg gatcatcaac actttatatc tatcgatctt gacagttgtc
    57721 cttacttatt tgattgctgt gcctctgggg atgcttgctg gccggtatca aaattcaatc
    57781 ttggataaga ttgtcgtaat ctacaacttc tttagttttg ctgttccttt atttatcttc
    57841 ggcttgatca tgctatttgt ttttggttat cgtttaggct ggttcccaac aagtggatca
    57901 caaacactag gtttgcaagg tggatttatc actcaatgga tagaccgttt gaaatatatt
    57961 ctgttaccat caattaccca agcatttttg gcgactgccg tcacaatcca atatctgcga
    58021 agtgaagtaa tcgattcgaa atcgctcgat tttgtcagaa cagcccgttc caaaggggta
    58081 ccgacgaata aagtattcag tcgacatatt ttccgaaatg cagcgttgcc gatggcttct
    58141 caaatggggt atgaaatcac ttcgttgatt gctggttctg tagttatcga aaagattttt
    58201 ggttatccgg gagtcggaaa actatttatt gattccatcg gccaacggga ctataccgtg
    58261 atcacatcct tagtattgat tttaggaatc gcgacgctag tggggacatt actttcagat
    58321 atcatcatga gtatcgttga cccgcgtatt cggattcaat aaaaccaatc agaaaggaga
    58381 atggatcgat gagtgaaaaa aacaatacag cagttcaaga aagtattcct cctatgggga
    58441 tacgaatgat tgctcgagaa tttaaaaaag ataaaattgc tattttttca ttaggtttgc
    58501 tagtggtttt attattagtg atctttatcg gtgcgatgct gaccgatcaa gacaaagtga
    58561 tgtatgttag tatcttcgac aaatacgctg caccaggaac agtttcgaca caaggacaaa
    58621 agttcattct gggagcagat gaaggcggac gtgatgtatt aggacaattg atcataggtg
    58681 ctagaaactc tgttacgatc ggatttgcga tcacgatcct tacttcgatc atcggggttg
    58741 gattagggat catctctggc tactacggag ggatcattga caacatcttg atgcggatcg
    58801 ttgattttat catgattcta ccgatcatgc tgatcattat cgtcttcgta tcgattattt
    58861 ccagatacaa tgtctggtcc tttatattca tcatgagtgc attttattgg gtagctaaag
    58921 cccgattatt ccgaagcaag acattatctg aagcaagaag agattatgtc agtgcctcaa
    58981 aaacaatggg aaccaatgat tttaaaatca tgttccgcga aatcatgccg aatctaagtt
    59041 cattaatcat tactaatttg acgatgaact ttgcggcaaa catcggtatc gagacaactt
    59101 tgactttctt aggtttcggc ttgccggcaa atgtacctag tttaggtaca ttgatcggtt
    59161 atgcaagtaa cggagaagtc ttagtgaatc ggcaatggat ctggttaccc gcatcaatcc
    59221 ttattttagt tttgatgttg agtatcaatt atgttggaca agcattcaag cgttctgcag
    59281 atgcgcgcca acggttaggc tagtatagaa gcgaaggggg aaataggaat gaagaaaacg
    59341 atttttggat ttgcagcgct gatgtctgct gtcgttcttg cagcatgcgg gggcggaggt
    59401 acagatacct ctggaaacaa ctctggaggc aacggcaata acaaagagga attaactttt
    59461 ccaattgcaa caaaaaataa tgatgatgca atcgaagacg gcgaattaga agctgcggtc
    59521 gcaacggaca gtcagtttaa aggattgttc cagtgggagt tttaccaaga ttcatatgat
    59581 gcagctttta tggctccttc tcatgaaccg ctatttgcaa acgatgacga tttcagaatc
    59641 acagacgacg gagctgcaac gcttgatcta gatgaagata cgaaaaaagc gacaatcaaa
    59701 gtaaaagaca acgtcaaatg gtcagatggt gaagatgtaa cggcggacga tgtgattttc
    59761 ccttacgaaa tcattgggaa taaagattac actggtatcc gttatgacga cactttccgt
    59821 aacatcgtag gtatggaaga atatcatgat ggaagtgccg acacaatctc cggaatcaaa
    59881 aaaatagacg acaaaacagt tgaaatcgaa tataaagaag taaacccaag catgcttcaa
    59941 tcgggtggtg gtatctggtc atatgcagca ccaaaacata cgttagaagg tgtagcaatc
    60001 aaagatatgg aatcaagcga tcaagtacgt aaaaatccag tgacttttgg cccttattac
    60061 atgagtaata tcgttgcagg agaatcagta gaatacttgc caaacgagca ctactggaat
    60121 ggtacgccta aattgaaaaa gatcacgatg aaatctgtac cgatggcaag tgcaactgaa
    60181 gcattgaact ctaaattata tgatatgatt ttccaaatgc caacagatac ttacgatacc
    60241 tataaagaaa ttgctggcta tacaaactta ggccgtgaac aaacttctta tacttatcta
    60301 ggattcaagt taggtaaatg gaatgcagat acaaagagtg tggaatacaa tccagattca
    60361 aaaatggctg ataaatcatt acgtcaagca atgggctatg cattagataa taatgcagta
    60421 ggtgaacgtt tctatgcagg tttgagaagc aatgcgactt cattgattcc tccagtattc
    60481 cagtcatacc atgatgatga gatgaaagga ttcacacaag atctagacaa agcgaaaaaa
    60541 ctattagatg atgctggcta caaagatgtg gatgacgatg gtttaagaga agacaaagat
    60601 ggaaataaac taacaatcaa ctttgcttcg atgtccggtg gggaaacagc gcaaccattg
    60661 gcagattact atatccaaca atggaaagaa attggtttgg atgtccaata cacaacaggt
    60721 cgtctgatcg aattcaattc tttctatgat aaattagaaa acgatgatcc tgaaattgat
    60781 gtttaccaag ctgcttggaa tacaggaact gatccaaatc caagtggact atggggacca
    60841 aatgctgcgt tcaactacac tcgttatgaa tcagaagaaa atacaaaatt gatcaacgat
    60901 atcagttcaa gcaaagcatt tgatgaagag taccaaaaag aagcatatca aaaatggcaa
    60961 caatatgcat ttgaagaagc atttgcgatt ccaacgttgt tccgtaatga agtattgcca
    61021 gtcaacgacc gtgtcaaaga ctgggattgg tcttatgatg taccaaaccc atgggcaaat
    61081 gtttctgtta cagcagattc acgttcataa tcactaaaaa tgaccgaaaa agggcgatgt
    61141 cctttttcgg ttttttgata tttttctgtt tatttctcta atattcaggt caaggcgctg
    61201 atttcatgac ttctccaata aacggtgttc aaagtccagt ttctcggtat taagtcaaat
    61261 ttatgcaaaa atatggaaag ccattttcac aaaatttttt cttcatactc gaaactaaac
    61321 gaatttttca caacttctcg tcaatcacta ggattattaa agctttactt accttttgac
    61381 cgaaccattt caaatttgac aaaaaaccag tataataagg aagtatcgaa aaaatatcca
    61441 taaaaggaat gtggaaaatg gacaaccagc tgacaaaaga actaaaagaa aactataaca
    61501 tcgtttttca cgatctaaat ttgcttgaac aagcttttac ccattcatcc tatgtgaatg
    61561 agcatcgcaa tctgcaatta tcggataatg agcgacttga atttttagga gatgccgttt
    61621 tagaactgat ggtttctcag tatttattcc gtttatatcc tcatttgcca gaaggaaaat
    61681 tgacaaaaac acgagctgcg atcgttcgcg aagacagctt gtcgaaattt gccaaagaat
    61741 gtcactttga tcaatatgtt ttgttgggca agggagaaga gaattcagga ggacgtacgc
    61801 gaccagcatt gctttgcgac ctattcgaag cttttttagg cgcgttatat cttgaccagg
    61861 gattcgacac gacccatgca ttcatcgaaa aagtgatttt tcctaaagtc aaagcaggtg
    61921 ctttttcaca tgagatggat cataaaacaa aactacaaga agtcttgcaa aaatcaggtg
    61981 atgtatcaat cgaataccga ttgatcaatg aagaaggtcc agctcatgaa cgagtatttt
    62041 ggatcgaagt ttatgtagat gatcaattga ttggcactgg acaagggaaa tcgaaaaaat
    62101 tagcagaaca agctgcggcg gaaaatgcat tggcagcact gtaaaagtaa gtgagggaaa
    62161 gctttgtatt tgaaacgaat tgaaatagcc ggttttaaat catttgcaga caagacagtc
    62221 attgattttg aaaatagcgt cacagcagtg gttggaccaa atggcagcgg aaaaagcaat
    62281 attacagagg ctatccgctg ggtattagga gaacaatctg ctaaaagtct gcgaggcgga
    62341 aaaatgccgg atatcatctt tgccggttcc gatacccgta agcagctgaa tattgcagaa
    62401 gtcacagtga ttttagacaa tagtgatcat tatctgccat tggagtacaa tgagatcagt
    62461 gtaacccgcc gttatcgacg gactggggaa agcgagtttt tcatcaataa acaaagctgc
    62521 agattaaaag atatccaaga attgttctta gattctggat taggaaaaga atcgttctca
    62581 atcatttctc aaggaaaagt agaagcgatt ttcagtagta aaccggaaga ccgtcgtggg
    62641 atctttgaag aagcagctgg tgtcttgaaa tacaagcagc ggaaaaagaa agcagaacag
    62701 aagctttttg aaacagaaga caacctcagc cgcgtccaag acatcatcca cgaattggaa
    62761 gaacagttaa ctcctttggc cgcccagagt gaggcagcaa aggagttttt acggctaaaa
    62821 gaaacactga ctcaaaccga tgtctctttg atggttgctg aaatcaagac agcaaaaaaa
    62881 gattgggaca acaaacaagc acagcttgcg aaattcaatc tagaattagg caaactatct
    62941 gagtcgatcc aagaacaaga atccattttg gcgaagcagc gtaaagaaaa tgcgcaagcc
    63001 gatcgtctga tcgaaaaaaa tcagcaagta ttattagatc tttcggaaaa actgaagcag
    63061 acagaaggac aaaaagatgt tttgcaggag cggacaaagc atacacaaaa aagctcgcaa
    63121 gaatatcaaa cttcattagc agaagcacaa aaaaaggtta aacattttga aaagcttcaa
    63181 gaaagcttga tgaaagcagc agcagaaaaa gaaacagaga tccaaaaagc tgaagcaaat
    63241 ctcataaaaa cacagcaaga attagaaaaa taccaaaaat caacgaaaga attattggca
    63301 gaattaagag atcaatatgt tgatttgatg caagaacaag cagctgtagg aaacgaactg
    63361 aagtatctag aacgtcaata tatacaagaa acagcaaaaa gcaagcagac gttagccaag
    63421 caatcggaag tagaagcatc agtagaccga ttgatcttac aaaaagaaga attgacacaa
    63481 aagcaggcgc agctaaaatc atctttaact gaaacaaaag agaagttaga aatgatccaa
    63541 caaaacggga aaaagttcca agaagcatta gcaaaagaac agcctaaaat gtatcaatta
    63601 atgaatcaag tccagcagct acgtgctcgt aagaaaagcc ttcaagaaat ccaagaaaac
    63661 tattttggtt tttaccaagg ggttcgattg gtcttgcagc ataaacagca gctttcgggt
    63721 attgtcggag cagtggctga actgatcgat gttcctgcag atttcacgtt agctatcgaa
    63781 acagctttag gtggggcagc ccagcatgtc atcgttgaaa atgaaaaaga tgctcggcaa
    63841 gccatcacgt atttgaaaca gcaaagagga ggaagagcaa cattccttcc actgacgaca
    63901 atcaaaccaa gacaattacc ggctcatata ttgacacaag cagcagctgt agaagggttt
    63961 atagggattg ccagtgaaca agtcagttat cccgatcaaa tccaaactgt ggttcaaaac
    64021 ctgctaggaa cgatcctttt agccaaagac ttaactagtg ccaatgcaat cgcgcaaacg
    64081 atccgctatc aatatcgagt ggtttcctta gaaggtgatg tgatgaatgc cggaggatcc
    64141 atgacaggtg gagcgaataa acgaggaaac caaggcagtt tgtttgtaca aaatcaagaa
    64201 ttgaaacagt tgactagtga atttgaagaa gcagataaac aactccaagc acaagaaaaa
    64261 aaagttcagg agctgcaaca agaaacagct cgtttagccg aagaacaaga agttttgcgt
    64321 acacgaggcg aacaattacg ttttgaagaa caagaagcga caaatcagct acaaaacatc
    64381 ataaatgaac ttgaacgttt tgaaaaagaa aagcaaatct caacttttga gacacgtgaa
    64441 ctgcagcagt ttatcgaaga ttacgaaaag caaacgaacg aattgaaaga caaacaaaca
    64501 gatcttgaat cgcaacgaca aaaaatcgac gaagaaatca aatcgttaag tcaagaaagc
    64561 gaccagatgg aagccagaag agcacaagta caaagtcaaa aagcacaaga acaagcagat
    64621 cttgctgtct tgaaagagca gtttaatcat ctgcagatcc agctccgcgg tgcccgagtc
    64681 caaaaagcag aggcaaccga acgtcaagaa gcgatagaaa agcagttggc gacattgaca
    64741 gcagactttt ctgatcatga agtcacagaa gaaagtttgg aaaaacaaat taacgaatta
    64801 tctgctcagc gagaaacatt aaaagccgag ttggcaaaag ccaaagagca gcgagataga
    64861 aggcaaaagg agatcgataa gcttgaagca gtcttggcag agcgtaatcg tgagcaaaaa
    64921 gcacgactgt cggaacaatc caaattagaa gtccaaaaag accgagctga aatgatttta
    64981 gataatcatt tgacctatct gcagtcagaa tatcagctga catttgagaa agcttcccaa
    65041 gactatcaag aaacaaccga tatcgaagac agtagaacaa aggtttcatc cttaaaagaa
    65101 cagattgaaa aactgggacc agtaaactta aattcaatcg aacaatacga acaagtcagt
    65161 gaaagacata cattcttagc aacacagcga gatgatctgt tagcagcgaa aaaccaattg
    65221 tttgaaacga tggatgagat ggatgatgaa gtgcggacaa gattcaaaga agtatttgaa
    65281 gctatccgtc aagaattcaa aattgtcttt ccaaatatgt ttggcggcgg taaagctgaa
    65341 ttagtactga cggaaccaac tgatttgctg aaaacaggta ttgagattga agtacaacct
    65401 cctggcaaaa aactgcaaag tctaagtttg ctttctggag gagaacgagc acttacagcc
    65461 atcgcgttgc tcttttccat tatccgtgtc tgtcctgttc cgttttgtat cttagatgag
    65521 gtagaagcag cgttagatga agccaacgtg aaacgttttg gtcgttactt gagcgatttc
    65581 caagatgaca cacaatttat cgtagtcaca caccgcaaag gaacgatggt cgcagcagat
    65641 gtactgtacg gagtgacgat gcaggaatcc ggtgtatcaa aaatcgtttc tgtacggatg
    65701 gaagatatca atgaagaggc gaaaatcaac gaaacgaaag tgtaggaacg aaaatgatca
    65761 aattagtagc aatcgatttg gacggtacat tattaaatga acaaaagctg atttcagatg
    65821 agaataaaca agcattagca caagcaaaac agcaaggggt caagatcgtt ctatgtacag
    65881 gacgcccctt agctgcgatg gcgcattatc tgcaagaatt aggactggta gatgaaggtg
    65941 actacagcat cactttcaac ggcggtttgg tacaaaaaaa tgatactggt gaaatcatgg
    66001 aaaagaaagt gatggaagta tcagatatcc aacgcttata caaactggct cagcaattgg
    66061 atctgccact agatgttttg tctgacaatg tggttttaca gctgcctagt gccccaagga
    66121 agcaatcctt gtacaatgtg ttgaataagc tgctgcaatt ccaaccagcg gatataagcg
    66181 atattacaga tgaatttgtg cttaataagg cagtaatcgc ttatgaccaa gaagaattag
    66241 atcctaaaat caaagaaata ccagcagaat tccatgaaat gtatgagatc atcaaaacaa
    66301 gaagtatgct tttggaattt atgccaaaag gtgttacaaa agcttatggt atttctttat
    66361 tggcaaaaga tcttggtttg aaacaagaag aaatcatggc gatcggtgat gaggaaaatg
    66421 atttaccgat gatccaatat gctggactag gcgtagcgat ggagaatgct gtgcctttcg
    66481 tcaaagaagc agcagatttc gtgacagcca gcaatgaaga aaatggcgta gccaaagtga
    66541 tccaaaaatt tgtattagag tagggggagt caaatgggat tttttgataa aatcaagcgt
    66601 gcttttactg gcgaagagaa aacagaagaa gttgaagtac aggagaagta cgacaagggt
    66661 ttagaaaaga cgcgtaaaac atttggtgaa cggatgaatg agttgtttgc caattttcga
    66721 acagtcgatg aagacttttt tgaagaatta gaagaaacac ttatcggtgc agatgtaggt
    66781 tttgaaacag cgatacgaat taccgaagca ttacgtcaag aagtgaaact cagaaatgcg
    66841 aaaaaatcgg cagaagtcca aaatgcgatc atcgagaaac ttgtggatct ctatgaagcg
    66901 gaaggaatca atgaagtaaa tgaactaaat atccaagaag acggactaac agttattttg
    66961 tttgtcggtg ttaatggtgt agggaaaaca acaagtattg gtaaacttgc ccatcagttc
    67021 aaaaacgaag gtaaaaaagt attgatggca gcagcagata ccttccgcgc tggagcaatc
    67081 gaccagttag ttgtctgggg cgaacgcgct ggtgttgaag ttgttcgtgg caatgcagga
    67141 ggcgatccag cagctgtcgt attcgatgct ttggaaagag caaagacaga gcaggcagat
    67201 gttttactag ttgatactgc aggccgactg caaaataaag tgaacttgat gaacgaatta
    67261 gaaaaaataa aacgagtaat ccagcgggaa ttaccagaag caccccaaga aacacttctt
    67321 gtattagatg caaccactgg tcaaaacgcg atggttcaag caaaacaatt caaagaaaca
    67381 acagatgtga ccggtcttgt tttgacaaaa ttagatggta cagcaaaggg cggtatcgta
    67441 cttgctatcc gtaatgaatt gcatttacca gtgaaattgg tcggtcttgg tgaaggaatc
    67501 gatgacttgg agccgtttga tccaaatgat tttgtcgttg gattgttcaa aggattacta
    67561 aaagaagaat aacccatgtc taaaaagcag gagctgtgac aaaagttgca gctccttgtt
    67621 tgaatgattg tttttaacat agctgtgttt ttgatgcctt catttttata cttatttgta
    67681 agcggttctc aaacaatttc gttctttttc ttagactttt tgattataat tagattcata
    67741 tgaattggag gtcacttaat gatgaatttt aagcaattat tattgcatgt caatgcgcgc
    67801 ccttttatcg accaagctcg atttggtata gaacgggaag gacagcgggt tgatcttgca
    67861 ggaaatctag caaaaaccga tcatccagca atctttggcg atcgatccta tcacccctat
    67921 atccaaacag attttagcga aacacaaaca gagatgatca cccctgttac cgattctatt
    67981 cccgaattat ttcagtatct cgctgctgtt tatgatgtga ctgctcgttc tataccgaaa
    68041 gaagagatga tctggccatt aagtatgcca cctgccttac cggaaaaaga cgaagagatc
    68101 attattgcaa aattaaaaaa tttcgaagat gtcttgtatc gacgttattt agcaaaagaa
    68161 tacgggaagc gaaaacagat ggtaagcggt attcatttca attttgaatt tggcgatgag
    68221 ttgctaagaa cattgttcag ccatcaggaa gaatttcaag atttttccga attcaaaaca
    68281 gaactttatt tgaaaacagc gagaaacttt atgcgctatc gctggatgat cacttattta
    68341 ttcggtgctt caccaatgag tgagaagaac tactttttag atgaatcaca tccgcaagaa
    68401 cctgttcgca gtattcgcaa cagtgcgctg ggctatacga atcatccaaa tgtgaaagtt
    68461 tcctatgctt ctatgaaaca gtatttagca gatatcgagc gaatgatcga agaagggaaa
    68521 ctttcggagg agaaagaatt ttatacaccg cttcgtttcc gaggcggaaa gaaagtcgca
    68581 gatttagcaa caacaggtgt tcgttatatt gaattgcgga atatcgattt gaatccttat
    68641 gcaagattgg gtatcaatcc agagcaagtt cggttcttac aattattcct gatgtacatg
    68701 ttatggacag aagaaaaaga agactgtgac caatgggtag cagaaggtac gactcgaaat
    68761 aacaaagtag cactagaaca accatcagat caaacagaat ttcatcaaga aggtagagaa
    68821 attcttgaag gaatgaagca aatgctggtt gaattggatt ggttggattc tctttattta
    68881 gtagaggaag cattgactca aatggatcat cctgaacaaa cgttagcagc gaaactctat
    68941 caagaagcac agctatcgag tcagcaagaa gttgctgtgg cattgggaca tcaatattat
    69001 aaagaaagcc atgaacgtcc ctatcagttg gccggttttc gcgaaatgga actttctact
    69061 cagatattta tgttcgatgc catccaaaaa ggtgtccaag tcaaagtatt agatgagtcg
    69121 gatcaatttt tgcgtctgca attccaagac catgtagaat atgtgaaaaa tgcaaacatg
    69181 acaagtaagg acagctatat cgtcccactt atcatggaaa acaaaacagt aacgaaaaaa
    69241 gtcttaaaag aagctgggtt ccgggtacca ggaggcgcag aattttcatc catggaagaa
    69301 gcggtaaaag cttatccgag atttgccgag caggcatttg tgatcaaacc taaatcaacc
    69361 aattacgggt taggtatcac gattttcaag gaaggagcta gtctggaaga ttatcaagca
    69421 ggtttagcca ttgcttttcg tgaagacagt tcggttttag tagaagaatt tatgccggga
    69481 acggaatatc gtttctttgt gatcgacgga gaagtccaag ccatcatgtt gcgagtccct
    69541 gctaatgtta ttggtgacag tatccgaaca gtgaaagaac ttgttgaaga aaaaaatagt
    69601 gaccctttgc gtggaacgaa tcatcgtgca cctttagaat tgatccaatt aggtgaatta
    69661 gaacaattga tgttgaaaga acaagggttg acgatcgaat cagttcccca agccaatcaa
    69721 attgtttatc taagggagaa ctcaaatatc agtacaggtg gtgattcgat cgatatgact
    69781 gatgaatttt ctgaagctta caaaaaaatc gccgtttctg cggtagaagc actaggagct
    69841 aagattagtg gtatcgattt gattatacca gataaagaaa tcgatcctac aactgataaa
    69901 aaagcatatg ggatcatcga agcaaatttc aatccagcca tgcatatgca tgtttatcct
    69961 tttgcaggaa aaggcagaag attgacgatg aatgtattga aattgttata tcctgaagta
    70021 ttttaaaaga aaaagctttt gacagattgt cctatttgat gtcaatctga tcaaaagctt
    70081 tttttgcatg taaaaattta tgtgtttttt cgttttaaaa taaacgatcc cagaagcttt
    70141 ttttcttttt tggtttttct ttttcagctg gcgaagagtt ttcttctggg tatttttttt
    70201 cgatatcaat cacaggttca tttactgctt cttttgctgt taagagcaat ccgaattcct
    70261 caggatttgc agtgacgtaa tcgttgacta cagtgaaacg gctattgttt ttcgttgcta
    70321 gctggatata ttggttttgg acagaaaggg gtagagcccc attcaagagt atggaagcat
    70381 ctggatgttt tttgagttct tttaaaaagt tttctttgtt ttttggttgg atcatttcag
    70441 caacagtcat actaagatag cagcgttccc tgaatgtccc taaatattta tgctgttctt
    70501 cagggttcac taaaggtgta ccataaagtc ccttatccaa atggcttttt acatcatctt
    70561 gtgccataaa aaataccctc cttcttctct ttgtctttct tacgattata gcatattccc
    70621 aataatacct aaaacatatg aaaaagcggt tgcttttgtt caacgattca cttaaaataa
    70681 gaatgaaaat cattctcaat tagaaaggtg gattggatgc gctacggacg actagtagca
    70741 ttattagtta ttttaagtag tatttcattg ttcatcggag tatcgaatgt acaattgtca
    70801 gaactgctcc agttagatgg gcaaagctta caaatcttgc tagtgactcg tttgccacga
    70861 acgatttgtt tgatccttgt gggagcgacc agtagtattt gtgggttgat catgcaacat
    70921 ttgacccaaa ataaatttgt ttcaccaacg actgcgggca cgatggatag tgcgcgttta
    70981 ggtattttag tggctatgat tttcctacct ggtgcatcct tgattgtccg atccttgaca
    71041 gcattttgct ttgcttttgc aggaacattg ctttttttat cccttacgcg attgttcctc
    71101 cagaaaaatc aattgatgct tccgttgatt ggagtcatgt tagggaatat cattggttca
    71161 gttgctactt tttttgctta tcaattccag ttggtacaaa atatgacttc atggcttcaa
    71221 gggaattttg cgactgtgat acgaggaaat tatgagttat tgtatgctgt tgttccattg
    71281 ttgctcttgg tttggctatt tgcttaccga tttacgatca ttggtctggg cgaatcgttt
    71341 gcagtaaatc tgggaataga ttaccagaag atgcagtttt taggcattgg cttagtatca
    71401 ttggctagtg cagtcatgtt gatcatggta ggaagcattc cttttatcgg agtgatcatt
    71461 ccgaatcttg tctctagaat atatggagat caagtgcaca aaacaattgg cgtaactgct
    71521 ttagcaggta gtttgttctt agtattttgc gatcttgtcg ctcgcgtgtt gatttttcct
    71581 tatgaaatac cagtcagtgt gatcgttgga atcatcggtg gggctatctt cctttatctt
    71641 ctgataaggg gacgacgata tgcttaaaaa aaagccatct atttttattg gtatgcttgt
    71701 tcttgtttta tttgttacag gaatgtactt gacgatccat acatatggaa actggcattt
    71761 tgcatgtgca ttgaggagta agaaaatttt tgcatttatc cttgtctcgc tagctgtcag
    71821 cagtgccaca atcagctttc agacaattac gcataaccag tttttgactc cttcagtatt
    71881 gggacttgag tcgttatatg tccttgtcca aacggtcctt ttcttcttta tcggaggagt
    71941 gacgatgctt cagcagacag gtacagtttt tttcttattg aacgttgggc tgatggtcgg
    72001 gctgagtcta ttgttatttt tctttctttt gaaaaaaatg agagcgaatc tttttttatt
    72061 actgatgtca gggatgattt taggtacgct ttttggtagt gtcagtacct ttttacaagt
    72121 catcatggat ccgaatgaat atgatttgct tcaaggcaga ttatttgcaa gctttggcaa
    72181 tatccagagt cagtatcttt tgcctgcttc tttgatcatt atcggctgct ggtacctgtt
    72241 atttcgatat cgacatgtgc tagacgtttt ccatctcgga aatgaacaag cagtaaacct
    72301 cgggatagac acagatcgtt ttgaattttt gattttatgt tgtgtcagtc ttttgacagg
    72361 gacatcaacg gctcttgtgg gtccagttac ttttttaggg tttattgtcg caaatatcag
    72421 ttatcgtgtc ttttctactt atcgtcatgg tcagctattt atcggaagct ttctggtagc
    72481 tatgctgttt ctgacaggag gacagctcgc agtagagcag attttcggct ggaatacaac
    72541 agtgagtgtc gtcgttgaat ttgtcggagg aatttatttt gtcacaaaat tgattcgcga
    72601 aaggaagagt atcctatgat tgatttacaa aaggtcaata aactgtacca tggaaaatca
    72661 gtggttaaag atgtacagtt aacgattcct gaaaagaaat tgactgcttt tatcggtcca
    72721 aatggtgctg gaaagtcaac ggtgttgtcg atgatcagtc gtttgatacc aaaagataca
    72781 ggtgaaatct atttagacca taacgaagta aaggcttgga aatccaatga attagccaaa
    72841 aaattatcga tcctacgaca atcgaatgaa ataaatgtcc aaatcaccgt gaaagaatta
    72901 gtagaatttg gacgatttcc ttatacgaaa ggaaaattga cgacaaaaga cgaggaaatc
    72961 gttcaggaat cactggaaca ccttgggtta gaagaaatag cggatcaatc gattgacact
    73021 ctttcaggcg gtcaactcca acgtgcgtat attgcaatgg tgctagcgca agacacggat
    73081 tatattttac tggatgaacc tttgaacaat ctagatatga attttgcggt tcaaatcatg
    73141 cagattttaa aaaatttagt acaagaaatc gggaaaacaa ttgttattgt tcttcatgat
    73201 atcaactttg ctgcaagtta tgcagacgaa attgttgcaa tgaaagatgg acagttattt
    73261 acgcaaggaa cgacccaaga aatgataaaa aaagatgtat tggatgaatt atacgaaatg
    73321 gacatacgga tttgtgagat tgaaggccgc agattctgtc tttatttcta aaactaacat
    73381 taggagagaa gagatgaaaa aattagtagt aggtatcttg attctagcat catttggttt
    73441 agcagcatgt ggaaatagca acaacaccag tcaggcagac acaaaaaaaa gcagcacaca
    73501 aactgaaact acattgacga taacagatag taatggagac caaatcgagg tgccaaataa
    73561 tccagaaaaa gtcgtcgtat tcgacaatgg ttctttagat acgatggatg ctcttggtgt
    73621 tggagataag gtagttggag cagctacaag cagccttcct gagtatcttt catcctataa
    73681 aaaagtagaa tcagcaggtg gaataaaaga accagactta gaaaaaatta atcagcttca
    73741 gccagatcta atcatcattt ctggccgaca aagagatttt caaaaagatc taagtcaaat
    73801 tgctccgacc attttccttt ctttagatgc gaaaaatcca tgggaatctt tccagcaaaa
    73861 tgtcactgct ttaggggaga tctttggtaa gcaagaagaa gctaaaactc aattagagga
    73921 attatctagt gcaatcgatc agacgaaaaa gaaagcagaa gctactgaca aaaaagcact
    73981 agtcacactt gtgaatgaag ggcaattatc agcctacgga tctggttcta gattcggttt
    74041 catccatgat ttatttggct ttgaacaagc agatgatcaa atcgaagcat ccactcacgg
    74101 tcaaagtgtt tcttatgaat atgtgctgga aaaaaatccg gatatcttat ttgtagtaga
    74161 cagaacaaaa gctattggtg gagacgacag caaagatgat atttctgcca atgaactggt
    74221 agcacaaacg aatgctggta aaaatcagca gatcatctcc cttgaaccag atgtctggta
    74281 tttaagcggg ggcggtttag aatcaatgaa actgatgatc gaagatgtga atcaagcatt
    74341 taaatagcat aaataacaga ggattaaact ctcatactat gtaacaataa tgtttcttac
    74401 attcttaaat agcaagagcc tatcctcaaa gaagttatca aaaaccatcc gtaaaatcgt
    74461 attgatgatt ttacggatgg tttttattta tttgagaaat cttttttcaa cgtgaattca
    74521 ttatctacat catacgggtt gattctagaa tggggagtgg caaaaaatag tgtgatccat
    74581 tttttcagca tcaagatcgc ctcctttgat ttgaatcaaa ggtacaaagc gaaacttaga
    74641 taaaacttaa atttagatat ttttattttg taccgatctc ttctttaaac gatgttccat
    74701 ctgctgcttc tcggcaataa gtccactaga ctagaaaata tgagaagcta ttttctgtcc
    74761 agcgttctta ttactcaaag caaatcgcag ttgtcacaat ctcttctaaa cgatgttcca
    74821 tctgctgctt ctcggcaata agcccactag actagaaaat atgagaagct attttctgtc
    74881 cagcgttctt attactcaaa gcaaatcgca gttgtcacaa tctcttctaa acaatgttca
    74941 atcagctgac cttcggtatt agctcaaagc actgatttca caacctctat ttaggcatgt
    75001 gtctcagcaa gcggttgata gttgatgatc tgcatttttc gataaaaatc ggcgggaagc
    75061 ttactccacc gttttaataa ttgatagaaa taactctctt ctgctttgat tttatactcg
    75121 cttaatatca atccaaaact attcgttttt tttgaagcta attttttata aatatccaat
    75181 gctttggttt tatcttcatt gacaaagagt gtttttactt caatataaga accctcgata
    75241 ttttgtgttt cttcgataaa atagatgttt tttatatatt ccttcatagt gattcctcca
    75301 aagaagtctt ttatttgata agtttactct accgaagagt tgttaataat ccgtgaacaa
    75361 aaagtaattc tttttccaat agttgttaaa ggttttttat tttttatagt attttttgtt
    75421 atttaagaaa ggaataaggt taaacaaata acaggttgct ttttgggtct ttttccgttc
    75481 aagaaactga acgaagaaaa gggaaagttg tctcttttgt gataagagaa atcataataa
    75541 acgaatgact tactttccaa taaattgaga acagtcagaa ccagacaaat tagttgcatc
    75601 tgatgaataa agtgattatt ctatgacatg aggtgataca gatgaaatta gaagtgacaa
    75661 aagaagcaca agaagtattg aagaataaat tagaagcaga cgatcaactt ttattagata
    75721 tcgaaaacgg tgacggtcca tttgcagaaa gccaagtcag ttgccaattg gatacggcat
    75781 ttcgattgat cattgtcaaa aaagatacac aaacagatct aagtctttat tctgtagtgg
    75841 ctgatacacc agttggacca atcaaaatca aagacagtgc aatactttac atggatgatc
    75901 catccacact tgctttagaa ccaacttata atagtttaca attaaaagga ccaagcggct
    75961 tgagaaaagg caacttgcaa gttgttcgaa aagactagag ggataaaatg ggaaaattgg
    76021 cgatcatcag cgacctacat gtggacatca ataaattcgg cgaatcagag ctgatgcagc
    76081 tttggcaagt tttgcaaaag cacaagatca ctcggcttca tctagccgga gatacggcta
    76141 ataaagtaga ccgttgccta gctgttgtcg aatttttcgt caataaagga ttatctacga
    76201 catttcattt cggcaatcac gagttggcag atgtgcccaa tgaacagatg atggaccatt
    76261 ttccagaccc acatttttta aatgaacggt atattgcttt aaatgagcag accgttcttt
    76321 tagggatgaa tggctggtac gactatcagt tttccgaatt gaaagattac gaggcaatcg
    76381 tacgaatgaa gcgtttgtat tggtatgatc ggttcatcca gcgtgggaaa acagatctcg
    76441 aggtcaatgc agaaatgctt gcagctgcaa aaaatttgct agaccagctg gaagcaaaaa
    76501 aacttgaggt gattttatcc actcatttcg ttcctaaacg ggcatttatc atgtatcaat
    76561 ctgctcctta tgagcgttgg aacaaattaa atgcattttt aggatcagaa tcattcggag
    76621 aattacttga ccgttattca aatatcaaac aagtagtttt tggccatacg catcgtcgct
    76681 ttgaagataa atccatcggt cacacgattt acagctgcag accttttggt tattattatg
    76741 aatggcagct gacccgagat tttgtcttga aagaacagtt gctagacagc tatgatccta
    76801 tgaaattacg tgtcctcttg cgtgcccatc acccagcttt tcaggcctat caaacacaac
    76861 atttgcaaga ggaatttgaa caagcgatga caatcgttcc gtattgagac agcattagta
    76921 atgtgtaaaa gaaaatacct tgtaaaacat aaggataagt aagagcagta gatccattta
    76981 tcgtggatat gctgcttttt ttgcggaaaa taatcagcga atgtttattt gatcggatga
    77041 tttgtaactc gcagagtact agatgcaagc gtgtattctt tttttgaacg ataatcacaa
    77101 aaaaaaata
//
LOCUS       DAYNVV010000005        75915 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.005, whole genome shotgun sequence.
ACCESSION   DAYNVV010000005 DAYNVV010000000
VERSION     DAYNVV010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 75915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75915
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.005"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(99..3377)
                     /locus_tag="ACGXWR_000474"
     CDS             complement(99..3377)
                     /locus_tag="ACGXWR_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HFK0802091.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(3648..4193)
                     /locus_tag="ACGXWR_000475"
     CDS             complement(3648..4193)
                     /locus_tag="ACGXWR_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFK0802092.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(4205..4897)
                     /locus_tag="ACGXWR_000476"
     CDS             complement(4205..4897)
                     /locus_tag="ACGXWR_000476"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HFK0802093.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(4916..5200)
                     /gene="macP"
                     /locus_tag="ACGXWR_000477"
     CDS             complement(4916..5200)
                     /gene="macP"
                     /locus_tag="ACGXWR_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HFK0802094.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(5213..5776)
                     /locus_tag="ACGXWR_000478"
     CDS             complement(5213..5776)
                     /locus_tag="ACGXWR_000478"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFK0802095.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            6004..6666
                     /locus_tag="ACGXWR_000479"
     CDS             6004..6666
                     /locus_tag="ACGXWR_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HFK0802096.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            6790..7986
                     /locus_tag="ACGXWR_000480"
     CDS             6790..7986
                     /locus_tag="ACGXWR_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HFK0802097.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(8087..9463)
                     /locus_tag="ACGXWR_000481"
     CDS             complement(8087..9463)
                     /locus_tag="ACGXWR_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFK0802098.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(9500..10366)
                     /locus_tag="ACGXWR_000482"
     CDS             complement(9500..10366)
                     /locus_tag="ACGXWR_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFK0802099.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(10455..11480)
                     /locus_tag="ACGXWR_000483"
     CDS             complement(10455..11480)
                     /locus_tag="ACGXWR_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFK0802100.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(11498..12172)
                     /locus_tag="ACGXWR_000484"
     CDS             complement(11498..12172)
                     /locus_tag="ACGXWR_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFK0802101.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(12356..13249)
                     /locus_tag="ACGXWR_000485"
     CDS             complement(12356..13249)
                     /locus_tag="ACGXWR_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFK0802102.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(13323..15020)
                     /locus_tag="ACGXWR_000486"
     CDS             complement(13323..15020)
                     /locus_tag="ACGXWR_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFK0802103.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(15013..16326)
                     /locus_tag="ACGXWR_000487"
     CDS             complement(15013..16326)
                     /locus_tag="ACGXWR_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFK0802104.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(16326..20595)
                     /locus_tag="ACGXWR_000488"
                     /pseudo
     CDS             complement(16326..20595)
                     /locus_tag="ACGXWR_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333417.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
     gene            complement(20893..21411)
                     /locus_tag="ACGXWR_000489"
     CDS             complement(20893..21411)
                     /locus_tag="ACGXWR_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFK0802105.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(21413..22030)
                     /locus_tag="ACGXWR_000490"
     CDS             complement(21413..22030)
                     /locus_tag="ACGXWR_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFK0802106.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(22027..22881)
                     /locus_tag="ACGXWR_000491"
     CDS             complement(22027..22881)
                     /locus_tag="ACGXWR_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0802107.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(22878..23789)
                     /locus_tag="ACGXWR_000492"
     CDS             complement(22878..23789)
                     /locus_tag="ACGXWR_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0802108.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(23830..25164)
                     /locus_tag="ACGXWR_000493"
     CDS             complement(23830..25164)
                     /locus_tag="ACGXWR_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFK0802109.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            25372..26202
                     /locus_tag="ACGXWR_000494"
     CDS             25372..26202
                     /locus_tag="ACGXWR_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFK0802110.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(26446..26695)
                     /locus_tag="ACGXWR_000495"
                     /pseudo
     CDS             complement(26446..26695)
                     /locus_tag="ACGXWR_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(26886..27080)
                     /locus_tag="ACGXWR_000496"
     CDS             complement(26886..27080)
                     /locus_tag="ACGXWR_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802111.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(27585..27770)
                     /locus_tag="ACGXWR_000497"
     CDS             complement(27585..27770)
                     /locus_tag="ACGXWR_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802112.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(28620..28961)
                     /locus_tag="ACGXWR_000498"
     CDS             complement(28620..28961)
                     /locus_tag="ACGXWR_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFK0802113.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(28961..29191)
                     /locus_tag="ACGXWR_000499"
     CDS             complement(28961..29191)
                     /locus_tag="ACGXWR_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFK0802114.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            29478..29816
                     /locus_tag="ACGXWR_000500"
     CDS             29478..29816
                     /locus_tag="ACGXWR_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802115.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(30021..30583)
                     /locus_tag="ACGXWR_000501"
                     /pseudo
     CDS             complement(30021..30583)
                     /locus_tag="ACGXWR_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
     gene            complement(31315..31896)
                     /locus_tag="ACGXWR_000502"
     CDS             complement(31315..31896)
                     /locus_tag="ACGXWR_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFK0802116.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(32079..32705)
                     /locus_tag="ACGXWR_000503"
     CDS             complement(32079..32705)
                     /locus_tag="ACGXWR_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFK0802117.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(32727..34058)
                     /locus_tag="ACGXWR_000504"
     CDS             complement(32727..34058)
                     /locus_tag="ACGXWR_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HFK0802118.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(34213..34614)
                     /locus_tag="ACGXWR_000505"
     CDS             complement(34213..34614)
                     /locus_tag="ACGXWR_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFK0802119.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(34700..34906)
                     /locus_tag="ACGXWR_000506"
     CDS             complement(34700..34906)
                     /locus_tag="ACGXWR_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802120.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(35001..36503)
                     /locus_tag="ACGXWR_000507"
     CDS             complement(35001..36503)
                     /locus_tag="ACGXWR_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HFK0802121.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(36521..36976)
                     /gene="argR"
                     /locus_tag="ACGXWR_000508"
     CDS             complement(36521..36976)
                     /gene="argR"
                     /locus_tag="ACGXWR_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFK0802122.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(37074..37691)
                     /locus_tag="ACGXWR_000509"
     CDS             complement(37074..37691)
                     /locus_tag="ACGXWR_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFK0802123.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            37912..39285
                     /locus_tag="ACGXWR_000510"
     CDS             37912..39285
                     /locus_tag="ACGXWR_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFK0802124.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            39360..40472
                     /locus_tag="ACGXWR_000511"
     CDS             39360..40472
                     /locus_tag="ACGXWR_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFK0802125.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(40544..42181)
                     /locus_tag="ACGXWR_000512"
     CDS             complement(40544..42181)
                     /locus_tag="ACGXWR_000512"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HFK0802126.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAVVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(42349..42957)
                     /locus_tag="ACGXWR_000513"
     CDS             complement(42349..42957)
                     /locus_tag="ACGXWR_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFK0802127.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(43341..44492)
                     /gene="queG"
                     /locus_tag="ACGXWR_000514"
     CDS             complement(43341..44492)
                     /gene="queG"
                     /locus_tag="ACGXWR_000514"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HFK0802128.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(44511..45263)
                     /locus_tag="ACGXWR_000515"
     CDS             complement(44511..45263)
                     /locus_tag="ACGXWR_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802129.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(45404..46354)
                     /locus_tag="ACGXWR_000516"
     CDS             complement(45404..46354)
                     /locus_tag="ACGXWR_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFK0802130.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(46355..47194)
                     /locus_tag="ACGXWR_000517"
     CDS             complement(46355..47194)
                     /locus_tag="ACGXWR_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFK0802131.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(47191..47937)
                     /locus_tag="ACGXWR_000518"
     CDS             complement(47191..47937)
                     /locus_tag="ACGXWR_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFK0802132.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            48175..49545
                     /locus_tag="ACGXWR_000519"
     CDS             48175..49545
                     /locus_tag="ACGXWR_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFK0802133.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(49600..50496)
                     /locus_tag="ACGXWR_000520"
     CDS             complement(49600..50496)
                     /locus_tag="ACGXWR_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFK0802134.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(50610..50780)
                     /locus_tag="ACGXWR_000521"
     CDS             complement(50610..50780)
                     /locus_tag="ACGXWR_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802135.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(50777..51454)
                     /locus_tag="ACGXWR_000522"
     CDS             complement(50777..51454)
                     /locus_tag="ACGXWR_000522"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFK0802136.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(51545..52450)
                     /locus_tag="ACGXWR_000523"
     CDS             complement(51545..52450)
                     /locus_tag="ACGXWR_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HFK0802137.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            52625..54079
                     /locus_tag="ACGXWR_000524"
     CDS             52625..54079
                     /locus_tag="ACGXWR_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015486 -
                     glycoside-pentoside-hexuronide:cation symporter activity
                     [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide (GPH):cation
                     symporter"
                     /protein_id="HFK0802138.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVVPSH"
     gene            54095..55126
                     /locus_tag="ACGXWR_000525"
     CDS             54095..55126
                     /locus_tag="ACGXWR_000525"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFK0802139.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGHFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            55133..56320
                     /locus_tag="ACGXWR_000526"
     CDS             55133..56320
                     /locus_tag="ACGXWR_000526"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HFK0802140.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            56476..57858
                     /locus_tag="ACGXWR_000527"
     CDS             56476..57858
                     /locus_tag="ACGXWR_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFK0802141.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            57830..58216
                     /locus_tag="ACGXWR_000528"
     CDS             57830..58216
                     /locus_tag="ACGXWR_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802142.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(58416..59084)
                     /locus_tag="ACGXWR_000529"
     CDS             complement(58416..59084)
                     /locus_tag="ACGXWR_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HFK0802143.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(59273..60070)
                     /locus_tag="ACGXWR_000530"
                     /pseudo
     CDS             complement(59273..60070)
                     /locus_tag="ACGXWR_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(60351..61730)
                     /locus_tag="ACGXWR_000531"
     CDS             complement(60351..61730)
                     /locus_tag="ACGXWR_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFK0802144.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            complement(61905..63074)
                     /locus_tag="ACGXWR_000532"
     CDS             complement(61905..63074)
                     /locus_tag="ACGXWR_000532"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFK0802145.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            complement(63049..64200)
                     /locus_tag="ACGXWR_000533"
     CDS             complement(63049..64200)
                     /locus_tag="ACGXWR_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFK0802146.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            complement(64160..65521)
                     /locus_tag="ACGXWR_000534"
     CDS             complement(64160..65521)
                     /locus_tag="ACGXWR_000534"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HFK0802147.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            complement(65518..66519)
                     /locus_tag="ACGXWR_000535"
     CDS             complement(65518..66519)
                     /locus_tag="ACGXWR_000535"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HFK0802148.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            complement(66535..67230)
                     /gene="dapD"
                     /locus_tag="ACGXWR_000536"
     CDS             complement(66535..67230)
                     /gene="dapD"
                     /locus_tag="ACGXWR_000536"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HFK0802149.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            complement(67236..67952)
                     /gene="dapB"
                     /locus_tag="ACGXWR_000537"
     CDS             complement(67236..67952)
                     /gene="dapB"
                     /locus_tag="ACGXWR_000537"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFK0802150.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            complement(67949..68830)
                     /gene="dapA"
                     /locus_tag="ACGXWR_000538"
     CDS             complement(67949..68830)
                     /gene="dapA"
                     /locus_tag="ACGXWR_000538"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFK0802151.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            complement(68833..69633)
                     /gene="dapF"
                     /locus_tag="ACGXWR_000539"
     CDS             complement(68833..69633)
                     /gene="dapF"
                     /locus_tag="ACGXWR_000539"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HFK0802152.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            complement(69620..70879)
                     /gene="lysA"
                     /locus_tag="ACGXWR_000540"
     CDS             complement(69620..70879)
                     /gene="lysA"
                     /locus_tag="ACGXWR_000540"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HFK0802153.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            complement(71094..71264)
                     /locus_tag="ACGXWR_000541"
     CDS             complement(71094..71264)
                     /locus_tag="ACGXWR_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802154.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            complement(71365..71928)
                     /gene="efp"
                     /locus_tag="ACGXWR_000542"
     CDS             complement(71365..71928)
                     /gene="efp"
                     /locus_tag="ACGXWR_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFK0802155.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            72356..73273
                     /locus_tag="ACGXWR_000543"
     CDS             72356..73273
                     /locus_tag="ACGXWR_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HFK0802156.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            73286..74431
                     /locus_tag="ACGXWR_000544"
     CDS             73286..74431
                     /locus_tag="ACGXWR_000544"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HFK0802157.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            74602..75060
                     /locus_tag="ACGXWR_000545"
     CDS             74602..75060
                     /locus_tag="ACGXWR_000545"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0043768 - S-ribosylhomocysteine lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HFK0802158.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            75219..75689
                     /locus_tag="ACGXWR_000546"
     CDS             75219..75689
                     /locus_tag="ACGXWR_000546"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HFK0802159.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(75742..75857)
                     /gene="rrf"
                     /locus_tag="ACGXWR_000547"
     rRNA            complement(75742..75857)
                     /gene="rrf"
                     /locus_tag="ACGXWR_000547"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT        21681 a        15944 c        13428 g        24862 t
ORIGIN      
        1 aaaaagatag aaggaagtga gacatctatt ggtctcattt ccttctattt ttactttcct
       61 cagtcaattg ttttacatca taaaaggaga aattccactt atttttttcg ctgtttcatg
      121 acataaacaa ctacaccgat taacaaaatt cctccagcta atgctagcaa cgggttatta
      181 aattctcccg tttttgggag tccttgagtg ccattttttt cactttcttt tgctgtccta
      241 tccggatgag aaggttttcc atttggtttt ccatttggtg attcatttcc tggattttct
      301 ctttctggtt tgtcatttcc cgggggcaca tcggcagttt ctcgcacagt gatcgctttt
      361 tgctgggtaa cagattctgt atgagcagac catttttccc catcaaatat ttccgaacga
      421 taagtgactt ctagcgtata ttctcctttt gaaggtgctg aaaaaatagc ggtatgatta
      481 gaaaattgag cacttgactg tgtttcaacg atttggatct tttctgggaa ataacgcata
      541 tcttcaaaga caggcgttcc ttgatttggt gtgaaagttg acacaaaaac tgtaaaaggc
      601 ttcagttcaa tgatatttcc ttctgcattc tccgccacac catttgcttc ttgtataata
      661 atcggattat tttgttcatt tggttttgtc tgatttggtt cttgtacgat tgcatactct
      721 ggatattccg aagacggtga ggtttctccg tcaaaaatag cacctacaga taatggaaga
      781 ccatccactc tttccttttc tgtttgacga ttccccggtt taatctgcat cagtccatga
      841 acatggatac ttccattttc atagcgcgta acaggctgct gaccttcttt cgaacatgta
      901 tttagagact cgatccaatc ttttgatatg gtatgtccaa gagtattttc tgattgtttc
      961 tctcgttcat tccaatagta gttcaacgag tggtagattt gatcttcgtt ttgattcaat
     1021 gggcggatct gctctctcat ctcaagattc tctgttcgga aagataagat accagaagca
     1081 tggtagtctg tgtttcctgc tgaagaggta taaagagcca cattatatga accgttatta
     1141 aaacttgtac tgctattgac gataatatct gttccgctat tggaatcgat tcctttcgca
     1201 agattttcga aagacaaact attgatcaat tcatgagggc ccgttaaaga agaaccgccc
     1261 attttgaatc cattaccgtt accttctccc tcaattcctg gtacccagcc gtttcgataa
     1321 gcaactgagt ttttgatgat tacttttccg atcgaacctg tttcattttt agcaaaaagg
     1381 tcccaaccgt catctgcatt atgatacgcg atacaaccgt caaatacatt tccttctcct
     1441 attgtcagtt tggccgcaaa tccatcggca tcttcaaatc ctggatcggc attttcaaaa
     1501 gatgtacagt tcttgactaa gttatgcgcg ggccatgctt cgaaaggatc atttgagcta
     1561 ccgctgattt ggattcctgt atttccattc cgataagcat gaatctcttc gatcaaatta
     1621 tgatttccag aaatctgtaa tcctttttgc atagctgcac tatttgtaat gtcaaaccct
     1681 cgtaaacccc agtagtgact gaacagtgtc atcccatttc cagttccttt aaaatcaagt
     1741 acaggacgct tgttttctgg atttttctct gcaatcaact gaatcgggtt ttctcttgtc
     1801 ccgttaacgc cttttggaat cgtcaatcct ctttcgaagg aataagttcc aggcgccatg
     1861 acgattgtct gcccagcata tgcgtatctc aatgcttgtg tcagagataa tggattttgt
     1921 ctgcttccgt ttcctgcatc tgacccttct ggtgttacat aaactgtcga atatttaggt
     1981 ttacggtagt ccactgtatg aagaatctct tttgtttcat aactagtcat ctctacgtat
     2041 tcttctggcg gatagttttt atctggcgta aaactgaaag taaattcgtt cgttccttcc
     2101 atcagttttg tctgataatc aaattcccga ttcgcagtga tagccaagtt ttttgcgttc
     2161 ttaagcacct ctcctgttgc tttattttta attgtcaata atccgtcagc atttgctcta
     2221 aaggacatag tatgatcttg gtttcctgaa tgattactag aggtcacagt gtaaatcgga
     2281 tcaatcaagc gagtaggtct ttcttgccca ggaggatctg tcgcaggatc tgagtaagca
     2341 acttcgattc cttctacctt gatcgtcata ttccttgctg cagcaaatcc tgcataaata
     2401 accgattcat ctgaagcgta taatttttcc cagtcataca tgatgtcaga agccatttct
     2461 tctcctgttt caggatcgta ataatatgcc tctaaaccag tattcgtttt tttcatctct
     2521 acgtccagtt tagtaatcga gttcgtggcc ggaaacagat tcccatgacc gtttccgaat
     2581 atattataag aacctgtttc tttttccaag aaccctgctg aagtctctaa aggtgttgtt
     2641 tccactgaga cactcccagg agctggcgca gcttgcggat cttcagatga tattcctgtg
     2701 attgcccgtg tccccaatcc aagtcgcatc gtatatttgc tgccgctcgt gttgaccact
     2761 tcttgtctat ccgagtccca gacatattcg atccgactgc ctagtatggc aaatgaattt
     2821 gaataaaatg cctgcccaaa caaatgattt tttggtactg cgtctcttac cattaaagca
     2881 aatccttctt gggcattcgt ataggtccaa gattctattt cgatcgtcgc ccgcatccta
     2941 aagttgatgt ctttggggat tgcttgataa taataggtca ttccatctga tccgcttgac
     3001 tggaattttc cgccgttatt cgtggaagag agccgcacgc cgtcttctaa tggttcaatg
     3061 gcatacctac tagcacttgt gctttctccg aaaacaaccc ctttccactc ttcatttgct
     3121 tcttcagatt gcttttttgt cttttcattt tctgattctt tcatcatagg atcatttcct
     3181 tcttccgtat ccatatcttc actagttctt ggtatttcct ccattgttga catcccttca
     3241 atgttcacgt gtgcattttc ttcgttcaca gactgttgtt cgttagcagc aacttcaacg
     3301 acagaaatta aaaccggggt actgagcata aggagattca tcattagcgc actgtatttt
     3361 atacgttttt ttaacaagtg tattcctccc gtaacaaatt agaaagcgtt tacttaaagt
     3421 attacctaat ttatttttac tgtcaataaa aaacaaaatt ataataagtg tattttataa
     3481 aaagaaaaaa tataacttaa gttgttgata ataaagagat ttattaacgt aaaaagaata
     3541 agttttttta aaataacgta taaaaaagag cataaaacaa agtcgtttgt tttatgctct
     3601 tcttttatta ttttgtgctt tttattttat caaatcactt tgttttttta taaaatttct
     3661 gcgcctagtg tggactcaaa atgtctcaat gcccattcat gtccaacggg atcgaaactt
     3721 gccacggcat ctttgaaaat atggagtttg tatcctagat tatacgcatc gactgctgta
     3781 tgcaacacac agatatctgt acatacgccg gtcaaataaa tatctgtgat ctggcgttct
     3841 cgcaaacgga tgtctagatc tgttccacta aaagcggaat aatgccgttt gtctatccaa
     3901 taaacatttt cctcttgctc atagtcttgg tataaacttt ttaaagagcc gtacaattcc
     3961 cgtccacccg ttcctatcac attatgcgga ggaaataagc ggttctccgg atgaaaggaa
     4021 tcttttggat catgcgcatc aatggcaaaa acgacaaaat ccttttgatc aataaacttc
     4081 tttgtatgag cagtcagctt tttttcaatt acttgtcctg ctgtcccagt agtcagcttt
     4141 ccatcctctg caacaaaatc atatgtgtag tcaatcgaga tcaatgcgtt catcttagtc
     4201 ctccttatac gagatgtttg acaaattcga tcaccatttc tgctgatcgt ttgcctgcgt
     4261 cttcgataaa ttcgtcaaag ctttgtgtcg ccgagtgatc tgctgtgtcg ctcattgcac
     4321 gtacgatcaa aaatgggata ttgaactgac gagctgtttg tccaacagcg gctccttcca
     4381 tttcgcaagc taatgcttca gggaaattcg ttaagatttc tttgatttta tctggcgagt
     4441 cgacaaatgt atcacctgta acgatcaatc cttcttttgc gttcaaattc gttgcttttg
     4501 ctgctttaac catttcactg cgcaaatatg tgcttgcttc ataatataga ggcattcctg
     4561 gtaattgtcc tgggttgtag ccaaatcctg ttgcatctgc atcaaaataa gctactttgt
     4621 ctgatataac gatgtcacct acttgtaagc cttcaccgat tccgccagct gaacctgtat
     4681 tgatcaccat gttcacgccg tattgttgga tcaacagact tgtggtaata gatgctaaga
     4741 cttttcctat accggaacgt acgacgatca cttcgtggtt acctaatgaa cctgaaataa
     4801 ataaagcgcc tgcgcgttcc catgataatg gttcgcttag gttctctctc aaaattttta
     4861 cttcttcttc cattgcgccg ataataccga ttttcatctt tttaattcct tctttctata
     4921 taaatgcgat tgctaaaaaa accacacata acattaggat aacaataata agagatttca
     4981 tcaaaaaaga gttccatttg gtcgtctttt cccgttcgct gatccttgtt ttcgtgattg
     5041 gtttattctt tttgctttct ttacgataaa agctggcaat ctttttttct tcttgctgat
     5101 aagctgtttc tgcttttcgc tgttttttta atgactcgct tgcttgtgct tgttgtcgct
     5161 tgcgaagttc gcttcgcgta ataagcggtc ctttggccat aagccgatcc ctctactttc
     5221 ctttggtcaa tagttcccag tattgaatcg cataaatcgt ctttgcatca caaatcaact
     5281 gatctttcat cgcttgttgc gcctcttcaa gagttagatg atacaactcc agtacttcgt
     5341 cttcatcttg tgctaaagga ttctcgacct tctctacccc ttgtgcatga taaatatgaa
     5401 ggacttcatt tgcaaaacct ggtgaaagat acatcgaagt aagatggctc agcgacttcg
     5461 cacgatagcc agtttcttct tctaattctc tagctgctgt catttcggga ttttgtcctt
     5521 ctcctggatc gatttttcca gctggaatct ccaaaatcac tttttctaaa ggttttcgaa
     5581 attgtttgac aagaagcaga cgatcttgtt cgtcaaaagc aatgatcccg acaccgccag
     5641 gatgaaatac cagttctctc ttcgaagttc ctccatctgg caaacgaact tcgtctacag
     5701 caacatcaat aatttttccg ctatagattt ctttgcgact gattgttttt tcttcaaatt
     5761 gctcattgtt cagcatatct tctcctgctt tctttgtaat cataactgct tttttttcat
     5821 ttttcaattt ttctcaaaaa ctccttatta gtttaccata gataaacctt agattttctc
     5881 taaatataga aaatccttct ttagtccgat actctttata gtagtccgta tgctaaaata
     5941 agtatgtaat cgaataacga aaagaattca atactcaacg ataaatgaca tggagggttt
     6001 attatgataa aacgaaattg gccgtggctt ctagcattgg tcttgctatt tctctttgtc
     6061 cgaaacaata gtttttcttt tgttctagga cttttattga taggtgtagt tttagttttg
     6121 tggggactct ttggttcgcg caggaaaaag ggaaaacaag aagaaattcc tgcactgact
     6181 gacgaacttg aaactcacta tgaaaaaagc ggtatgacag cgaatgaaat ttcatttttt
     6241 cgacaaacaa tgaatcaaac aaaaaatgag atcaatcaat tgcaaatgaa tatgcagcag
     6301 acagccaaac ttaaagcaat cgatctccgc catgatccag tcaaagcagc gaaagcttta
     6361 ttcaaagaat tggtgaaaga accaaaccga ctgcatgaag caagtcagtt tctttatacg
     6421 catctgccga atctagttga tttgacaaat aagtataatg agatcaatga ccatgagatc
     6481 aaaaacaaac agacctatga aaaactagaa gaaagcgcgc agatcatcga ccagctgtca
     6541 gctttaatcg cacaagatta tcaaaaattc gttgctgagg atctagatga tatcgacgta
     6601 gagatatctg ttgcgaaaca gagcttaaag cgtgataata aatatgaacc agaacaaaag
     6661 gattaactct tttgttcata aaagaagact cggaacattc agatgatgtc tggctgtttc
     6721 gagtactttt tctaaagtag agacattcat gtaagaatcg agaacagatt caacaaggag
     6781 gaatttttta tggatcataa accgactgaa acaaaagatg ttacaccagt taacgataca
     6841 cttgaagatt tattgaacaa cccgttttca actccaacag atacgctgac cacttcacaa
     6901 caagcggaga ttgatcagct ccaagagcaa cagacagctg ctcgtttaat tgacaaacta
     6961 ccggcggaac gccaagaaca agctaaacag ctagcagcaa aaatcgatgc taatgatgca
     7021 cagtctgtca tcagctacgg atcggctgcc caagcaaaat taagtgaatt ctcacaatcg
     7081 atgttgaatc atgtgcaagc acaagatatt ggtcctgtag gagattcctt aactgaactg
     7141 atgtatcgtc tccaagaagc caatcctgac gaactgcgtg ccggagaagg gaacatcttc
     7201 cagcgtgtct tcgggaaggt caaacaatcg atctatgaag tgacagcaaa atatcaaaag
     7261 attggtgcac aaattgacaa gatttcagtg aaattagata aagaaaaaga cggtctgcta
     7321 aaagataatc tgatgttaga acagctttac cagaaaaaca aagactactt tgatgcactg
     7381 aatatttata tcgctgctgg agaattgaaa atggaagaac ttcaaacaac gatcattcca
     7441 gaagcgatga aaagagcaga agaaactggc gatcagatgg atgttcagat tgccaatgat
     7501 tacacgcaat tcctagatcg tctggataaa cgtacgcatg atcttcgctt agctagacag
     7561 atcacgatcc agcaagcacc acaaatccgt ttgatccaaa acacaaatca ggccttggct
     7621 gaaaagatcc aagcatctat cgctacagcc attccgctgt ggaaaaacca agtcgtgatc
     7681 gcattgacct tgcttcgtca aaaagatgca gtaactgctc aacgccaagt ctctgaaaca
     7741 acaaacgact tattgaagaa aaattcagaa atgctgaaaa tctcagccat cgaaacagcg
     7801 aaagaaaatg aacgtggaat cgtggatatc gagacccttc aaaccactca aaatgatttg
     7861 atcgaaacaa tccaagagac attgcgtatc caaaaagaag gaaaagaaaa acgtcgtcat
     7921 gcagaagtag agcttggaca catggaagaa gatctgaaac aaaaactgtt ggatttaacc
     7981 caatagatca cctttcgctt gttactaaaa caaacgccca acaacagttt attacaactg
     8041 ttgatgggcg tttttcttat ctttcttcta acttctccat tggagtctat ttctcattca
     8101 tcttgctgtg tccatagcca tagccaaaat aaatgatcag tccaataacc attacgatac
     8161 cgaacacgat ccatgtcaca gtttgcagac gaagcatcaa tacaatacaa gtcaagatgg
     8221 agacgattgg caatagcgga acgaatggca ctttgaattc tccagctttt ggtttgccaa
     8281 acatttttct caacttcagt aagcctagac taacaagcat caaataggcg agcgccatga
     8341 tattcgttag ttccgctaat acattcaatg ggaaaaatcc ggcaaagaat acagctgcca
     8401 caccagcggc ataagtcgct tttttcggtg tacgatgctt ttgatcgatt tctgtcataa
     8461 acttaggaag taagccatcc ttgctgacag caaacagtaa acgagcaagt gaatacatca
     8521 tcgagatcgt taccgtcagt agcgttaaaa ttgcccctac agcgatcacc gcgcccactg
     8581 ttccatgtcc tacatacctc attgcaaaag ccactgggtc attgactcct agttcagtat
     8641 acggaacgat tcctgtcaag atcagcgtca cgatgatgta aaggacagta gcaatcagta
     8701 tcgaaccaat gattcctctt ggcacatctt tttgcgggtt tttgacttcc tcggctgcca
     8761 ttgcaacggc atcaaatccc aagaaagcaa aaaacacaag agctgcacca tctagcacac
     8821 cggaaaaacc aaaaggcatg aatggctgcc agttatcagg tttaacgaaa aatattccta
     8881 caatgataaa caacgcgatg ataccaaatt tgacatatac catggcatta ttcaaacgta
     8941 atgctttctt ggcttcaagc gacacgatgt aagtgacgaa tatcactacg agcaccgcaa
     9001 tcaagtcaat gtatgtacca ttttccggat tgtacccgcc agttaatgct tgtggaagtt
     9061 cggcccctaa acttttcaaa aaaccttgca tatagccaga ccatccggaa gcaacagagg
     9121 aaaccgctag taaaaattcc ccgatcaaca accaccctgt cagccaggca gcaaattcac
     9181 caaatacaac atacagatag gcatatggcc caccaatcac tggcactcgc gaagcaaatt
     9241 ctgcgaaact tagtccagac aaaatgacaa cgattgcagc taagacaaat gaaagtgaca
     9301 gtgctggacc agcattttga ttggccgcaa cccctgtcac cacaaatatt cccgtaccga
     9361 tgatcgcacc aattccaagc atgatcaaat cagacgtttt tagttctttt ttcatctcac
     9421 tcgtatgatt gagattgatc tctttcttac gaaacaaatc cattgaagtt cctccccatt
     9481 ttaggttgga aaacagcgat taaactgttt tcatataccc taaaaggata ccacctaaaa
     9541 tgactaaaag gcaaccaaca ataacataaa tgagctcttt tttcgttttt ctttcgccaa
     9601 ggatgaaaat cccacctaaa gtagagataa tgatccccat ttgtgaaagt gagaagccaa
     9661 cagctaaacc aagtgatttg actgttagaa gcatgcagat gtttcctaag ccccataata
     9721 atccacagat catgtttttc cacacaaact gatcgacttt aactttacgg aaagcaaaga
     9781 agcttgcgcc taagatcatt ccgatacttt gaggtaagat aattgacatc gcatccaaat
     9841 tcgcccagtt gacgatgatg gtatatacac cataaccaat cgtagagaag atcaatgctc
     9901 taaaaccctt accaaaatca agcattttat tatctgtatc tatttttcct tcgtcatctt
     9961 gtcgggcagt caaatacgca ccgcttacaa gaagagctaa agcaataata ccgtatacat
    10021 aatctttcgt ttgtgtccat tcatggaaga aaacggctcc cgcaatcgta ttcaaaatta
    10081 attgaaaacc agtagacaat ggtagcccta cagaaacacc catgtacttc attccatgga
    10141 actgtccatt ttgtccaaca ctccaagcta agccggataa aaatccgatc aagaaaatcc
    10201 aaggggtgat tacaggacta acaacgaaaa agacaactaa agaaaacaga aatgcaccga
    10261 tcgtcattcc tagtgtttgt tgattggcat cgccaccaat tttaccactt actaaaccaa
    10321 tactacccca tgccaacata gggactaatg ctattaaaat ttccataacc aatctccttt
    10381 tatttcacat gataagaaac ttatcagcga aaacgttaac aacacaagca ctttttttcg
    10441 tttctaacga ttttctaacg tttttcatta taaaaattta agattgggaa aaataaagtc
    10501 attgttgtcc cttttccttc agttgattca gccgtcaaat ggatacctaa tttttcggcc
    10561 agattttttg ctaaataaag tcctaatcct gttgaatgtg ttttgctaag tcgaccattt
    10621 ctcccagtaa atcccttatc aaagatccgt ttcaagtctt ccgctgggat accgatccct
    10681 gaatctttaa ctgaaaggct gactccttgc gcttcctttt ctatgctcac aatgatgttt
    10741 ccgtgatccg gcgtatattt gatggcatta ctaagcaatt ggttgaagat aaaagcgatc
    10801 catttagcat cggtcaaaac agtatgatcc tcaccaacga tctcgtagcg aatatttttt
    10861 tggataaaat aatttgcctg actgcgtatc acaggctgaa tgattccttt tagtccatat
    10921 tcttggatga ggtagtcccg cgagaaactg tcgagtcttg cataatacaa aacttgttct
    10981 acgtattcat cgatttttga taattcattt tctagtaatg tatacttttg atcgtcaata
    11041 tcgaactcga tcgaacgaac tagcaattta gaagcggaaa gtggcacttt gatttcatgg
    11101 acccatgagt caatataatc tttttggtct tgttgattac tgattgctga ttgcattact
    11161 tcttggtgtt cacggatcag ctgattgata tattcttcta ccagtttttc ttcttctgtc
    11221 ctcccaccac tcaaataatt ttgcaaaggg gaagtttttt gtatgtcggc taattttccc
    11281 caccatcttc tcttgctcaa gtaaccaccc agcagataaa aaatcagaaa gacgccctca
    11341 atcaaagcta aataagcaat tgtgctcaaa tcaactttga tgtttggcgc cagccacatc
    11401 acaaagatcg tcaatgcaat aaaaaacagc catcccaaga tcaatgtcca ctgatctttc
    11461 aaatatttaa aaaaattcat cttaaccgct catcctttca gggaacgata tatccctgtc
    11521 ctacttttgt ttcgatatat ccttggatac ctgcctgttc gatttttcgg cgtaaccgat
    11581 tgatgttgac tgtcaatgta ttgtcatcta caaatcgttc gtcatcccac agtgctcgca
    11641 gcaatttttc ccgacttaag atctttccat tgtgcttcat caaaataaat aatagacgat
    11701 attcattttt gctcaaatca atgatctctc cgttgatttc catacttccg ttgtcaacat
    11761 tcaacgtaat gccattgtgg ctcatcattt cactagataa ttctgtgtag ttgtaagaac
    11821 ggcgaagtaa tgcattgatt tttgcaatca gtacatcgat ttggaaatgt tttgtcacaa
    11881 aatcatctgc ccccatgttc atagccatga tcatatccat attcgtattc ctgctggaga
    11941 taaaaatgat cggtactttc gatacttcac gtattttttg acaccaataa tagccatcca
    12001 aaacgggaag attaatatct agtaatacaa gctgtggttc ttctctttca aagtctgaga
    12061 acacttgatt gaaatcggtc gttccaaagg tttcaaattg ccatttctca agttcctcca
    12121 tgatcaattg tcgaatgatc tcttcgtctt cgactaccat gatttttgcc ataaaaaatc
    12181 cctccatctt tcttcttgct actacaatat caaagaagcc cttgtgaaac aagttggctt
    12241 acctggaaaa tgtcatttta gcaaacgtta aaaaaaactg gaaatatgcg atttaatcgc
    12301 gtttgtctct tccaagcagc ttaaatttat tatgttattc ttaataattg gtctattatc
    12361 tgttattttt ctttcgttgt ttttgtcttt taaattttcg ataacaccaa taaccgaaaa
    12421 gcgttagcac tagcaatata cctagaagga gtataagtaa tcgataaaga tggtattttt
    12481 ttgtctgttc tatctttgaa gagacttctt ctgtaaaggg aactcgtctt cctgtcacta
    12541 gtaatcggtg agtgttcacg gtgtaaggtg tacaagtgat aagtgtgact agatcctgct
    12601 tttctctaat tgctaatgta tttgtttttg ttggaaggac aacaattttc tcaacgactt
    12661 cataagcgag catccgacca tacacttcaa gatagaatcg gtcatcttgc tccatttctt
    12721 caagatccgt aaagagtttt ttctcagcaa taccgctatg ggcggtaatc acggaatgtg
    12781 tactctctcc tccagttgga aaagaggtgc cttgcaggac tgtcgctcct ctatctaaca
    12841 aaagatcatt cgtttcatca aataaaggca agctaacatt gattttcgga atatagatgg
    12901 ctccgatcat atgttgttcg taatattctt ttcctggatt ttggacattt ctaaccgctt
    12961 gctcaaaagg atctttgact tgtcccattc ctgggattac tgatgtatga gcaagcgtct
    13021 gatttttctt ttcatgcact gctaattgtt gctcatgttt ttcttcttta tcgcgttcaa
    13081 gctgcttttg ataattctcg atccttcttt gatccaaata attgctgaga gcatctgcta
    13141 aaaatggata tgtaaaaact gcagctccgg caagaaacat cactgccata aataattgta
    13201 ataaaagact gatttgggtt tgaggtctat tacctatttt ctttttcatt ttcttcacct
    13261 tcttatttaa aaaaactgca gcaaccttta taaaaccgat tgctgcagct tatttttgtt
    13321 gcttatactt cagacttcat tttagattta cggtaccagc tgtacgctcc aatcatcaaa
    13381 cttattccga ttagtaagaa tgccaagagc ccgttcccac cagtagcagg aagtgacccg
    13441 cgtttcatat tcggtactct ttctggccct ggattttcta ctcctacgat ctgaatttct
    13501 tcattatagc ttccataaga gatgataaat tcagtaaagg ctgcctcacc tgttggaagt
    13561 acataacctt ctggcgccat ggtctctttc atttgatagg ttccataatc taacccttga
    13621 acctcaaagt atccatttcc atctgcgaca aattctgttg cttgtccgct tgttgcccac
    13681 tcaattctat ctgctcctga ttcataaaca gctaaaggcg actccccttt ataaaatatt
    13741 gcgtattcag aacggtcttc attccacaat tcgaatcttg catctttaag caattcactg
    13801 cttgatgcat catatttttc aaactttctt ccacctgttg tgactttctc tggcggctct
    13861 actccttctt cataatcaaa ttcatcattt cgtccgattt caataaccgc tgtgttgtta
    13921 tggaaatcat ccgcttctag ttctgtggaa accttcaaat tatacgtgat cgttaaatct
    13981 cctccacgtg catctgctaa tctacctaaa gtatctactt tggctactcc attttcttct
    14041 gtcaaaatcg tcacgacaaa cccgttgctt actacttcta ctatataatc ttgtcctttt
    14101 gttaaaatcg tctcgccggc tcgcacttct atttcctgat cataataagt tagaccaact
    14161 gtaggcgtat ctgtgatttt gtaatttttg ataacagcgc ttccgttttc aaggacagaa
    14221 tcgatgaaat aaggaatagg tgctgtgatc gtgtaagaag ccgtttttcc tctttctaga
    14281 tcaatataag aaatcgtttc ttgttctcca gcttcattaa taatcgttac ttgtctaagg
    14341 tcgctttcct ctacattcat ctgtttatct gcttctctga tttcgttttt cggatacaaa
    14401 tgcacatctg tattgtatgt gtctttccat gtagaaccat cccacacgcc atccaccata
    14461 tcaggcatca tcactggcat cataacaacc attggagacg cgattctgga aatatgagct
    14521 ggcgaataag tttctaagaa aagatagact ttatctctag aagaaggtgc ttcttccgtc
    14581 acttggacgg tagagaatac cgcttctcca gcttcattcg ttgtttgttt gtcaatactt
    14641 gtcagtcgat attttaaaaa ccaactttct gtgtgccgtt tttgaatcca ttcaatcgct
    14701 tcggcagaat taagaccgtc ttctcgttcc ggtgttaaag gattatctcg aatcaaatcg
    14761 taatatactt ccgttacgtc aaacaaatca aaatcgactc ctggaatatt ttcttcacca
    14821 aaatccgtag aaaccaatcc gctattcggt cgttcttccg gaacagatga gaaacctttt
    14881 ttgtgtaatg taatcgtcac ttcacttggt ttttgtgcga cttcttcggc tttgactagt
    14941 tttccgttcc cgaaaatccc tattcccgca gtaacgagta acagtacact cattcccgtg
    15001 acaatcattt ttttattcat ttttttctcc ccgttctttt tttattaata aaacagcacc
    15061 taacaataaa agaattccta gtaaagaaat caacgttctt gcttcattcg tttgcgggaa
    15121 tacggaccat tttcctgatt gacctggatt gcttggacca ctcggctctt tcggtttgtc
    15181 cgttgtttct tttacggtct cgttataaac acgtggtgtt gcggattcat aggcagagac
    15241 tggaactttc ccggattcta attcagccat ctcctgtccg ttaactacta catattgtgg
    15301 ttggcctttt gcatccaccc aaaattcagg gatgatgacc tcgattctct tacttgcttc
    15361 atccatctcg taaccttcca caccttttaa ttcttcaaaa taataggtgc cagaaggcaa
    15421 gaaacgttgt cctgtcgtaa caaggccctc tttatccgaa atgaatttgc ttacattttt
    15481 gtcattcaaa ggatcattgt ctgctggttt gatccattga tttttcaagt cattagcagg
    15541 agccatatct aaataatatt tccccccttc tatcatctga tatagagcaa aaacagcacc
    15601 ttctaatggt tttccttttt cagttgttcc tctttgacgt ccatacttga agaagtatgg
    15661 atctcttaga taaccgacat ttttaggata gatatgaatc tcttgcagtt cctcggttga
    15721 ttctgtcggg tgataaattg gcaaaatagc agcaattggg atagctgtct gatcgatatc
    15781 aacatccaat ccaacttctg gatcaatcga ttcttcgaaa atcaaataaa ctgcatcccg
    15841 atcttggttt ttcttaggtg ctttgatacg tgcaatcccg tctcctaatc cgccaaccgt
    15901 atctttccca gttgttaccg aagtccctat ttggacaagc ctttcttctg tgattagctg
    15961 acggatattg tttctgttcg tttcagcgat ttgctggacg aattctttag gagtcatgtt
    16021 ttcagcagct tttttttcat gataataatc ggtcatgtcg taaatggcaa atgtcgctcc
    16081 atttagtggc accgtctgtg aaatgatatc tgctgtttcc cctgcttcct cagagatagc
    16141 caagccatca ttttcatggt attcaaattg atcgttataa tcgatatctc gaatcatccg
    16201 tttatgcaac acgaattcca cgacatcttc ccctgattct tctgccgaca tcgcatgtgg
    16261 aagaaggact gctgcaagcg gtagtaaaac aagtaattga agcatcaaac acaacagctt
    16321 tttcattacc ttgctccctc ctttttagat tgtctgacaa acaaaccata ggctgctcct
    16381 gcaagcgcca tgaagaatgc agcaagcagg atatagaata atcgtccgga tcctcctgta
    16441 gcaggcaacg gattttcagg atcgttcccg acactaagct gtaatctgat tcgatttgtc
    16501 tccaaaagtt catattctaa ctcttgctgt agatcaggcg tctctgcttc ttcgtttgga
    16561 taatacgaaa tctcaacttt tagtgtaccc gcttcttttc ctggaactac ccgatcattt
    16621 tctatgtcag gttcttctcg ataactaatt tctaaaataa agtaacctgg aagttttcta
    16681 tagctgtcag gtgacttcac ttccttgatc cgatagaccc cttccaacaa gtctgaagca
    16741 ttgaataggg aagaatcgtt tggatctggt gccaagcctc cctcgatgat ttcatactct
    16801 cctgcactat tttgtttctc aattgaaaat tctgcgcctt caagacgtcg gctattcata
    16861 ctgtcaattt tcaaaagttc caaatcgatt ggcgctagtt catcttctaa ggttacttgt
    16921 agtacaccat cgatgatttc atagccttcc ggcaagggag cagtttcgtc ttcgatgacc
    16981 gtatcttcaa tgataaactt accttcttca ttcagtgcaa actggaacac ttgatcagat
    17041 agccgatacc catttggtgc gacagattcc gagacctcat attcaccaat agacagatgc
    17101 agaggttggt cgtaatttaa atcgacatac ttttctactc ctacggcacg agaatagaag
    17161 tatccgatcc caggcaaacg tttcgattct tctggttcta acggattacc agtgtatgct
    17221 cgatacagcg ggaaggaaga atcccccact ttcctgatat cgaaacctgc accatctaat
    17281 gtatggcctt catggtctaa ttttctaact cggatctccc gataatcaaa cgtattgtaa
    17341 gcagtgaatg ctacccataa acgatcctct tcatctgttg tatacgtgag atattgccaa
    17401 ttttcttcac ctgtttgctt gagttggata gtccctatag cattatcgta aagtcgcaag
    17461 atccatgtgt cattttcatc aggttctttg aaaccttctg ggttctggct ctcaatgatt
    17521 ttgtattctg catagttggt agtttcttca ctatccttat aaacaaatga atctggctct
    17581 ccgattggat gaataacttt ctcaccatcc acgattacat atttcccgtc ttcatctact
    17641 gaatagaacg tgagtctccc tttctcttcc tctacttcgt tcacaccaga aagccctttc
    17701 gctactggat atccgatttc cagtccgtta ccatctgttt cataaagttc aaactctgcg
    17761 ccattgattg gcatattact gccttcaatt agtttattga tattcatgtg gattggcttg
    17821 aattcatttc gcatttccag tttgacatac aactcatcat actctgtgcc ttctatgtta
    17881 ggctcttgta caacagaaag cttgtgatat tctccttcat aataggaatt cggatcttta
    17941 ccttccggtc cgccgactct cgaaccagat gtatattcat ctacaagctc gtagtgacct
    18001 aacatctcat cttcgttggc tgcatatttt ttgatttgga attgatacgt ctcatctact
    18061 aactgataac gtggtggtcc agcgatctct ctgatccaaa atatgtcgct gactgctcca
    18121 gtttcatctc ctaaaatcgg catcttcgtt tcaaagatcg ctattccgtc cgtggtagtt
    18181 ttacttgttt cgattggttc ggcttcccca ctctctggat tttggtcata taatgcaaat
    18241 tcgactccag ccaacggctc gccattttga cccttcttgc tgacttggaa attacggcct
    18301 ttatgttcgt aacgaatgga agaagatggg aaatacatcc gtccagtagt gatatcattc
    18361 tcataatcct ccaggttctg aatataggcc atattgttca ctgtgcaaaa atttccgtct
    18421 tgagctcccg catcaagttt tacttggtac ttgatcctga ccatttcccc ttcacctaaa
    18481 gaaatcggag aaaatttata agcttggttt tcccgtccga catacgttgt cggagtcgcc
    18541 actacttctg gtggggcttg tccatgacgt tcttcatccc atatttctgg ctcttggtac
    18601 ttcatgccgt tttctcctgg atctagatgg taaaactgaa tatctgccga tctgccagct
    18661 ccaaatggtg agacattaaa accagtttca tcataaagtg tggcttgctg gatcgttctc
    18721 ttgaaggtag aagagatatc ctccaaggct gtaacaatgt cattcttgtt gttcgcattg
    18781 taatatcgcg gtgttacgcc atcttcttct aaatcagcaa tatttttcaa tacatttcgt
    18841 ccaatagcat ctagtcgttg tctcccgcta acgtttccat cgattcctaa accaatggag
    18901 aagatacttg gcgggttctc ttgatacttg tttttcagcc aatgatgata agcaactgtg
    18961 ttgatcgcag atgacttttc ttgcgaagta ggactgccat tcgtattgtt attagaagaa
    19021 ccatcaccaa cccagtgagt cgctttatta tctccttctt ttacctctcc ataacgatag
    19081 tgtacattta cttcatcttc tggacggtta aagtcagatg cataggtaac tggatgagta
    19141 aaccctgcat tagaagtatt cccagaaaac tcctcaaaat ttctgaacaa aacgtcatta
    19201 tcttcagcaa tcttatcttc catcacagtc cagttgctcc aagctccatt agtgctcgta
    19261 cgataacttg actgaatcgg tgcataactg aaggtcggtg tcccatctcc cacaacgatt
    19321 aggatttttt ctggatttct attttctccg ccattgtctt tatacaatgt ttcatagcca
    19381 tttttaagcc ctagtgtaag cggagttcct ccgattggtg tacgatttaa tgctgtattc
    19441 tcacttcccg tcaaacgatt gatatcattt gtcaatggaa agatgtccga actgatttgc
    19501 tcatggttat tgatagctgt actattatgg taaaaattca ccataccgat tcgaatatcc
    19561 agactcgggt cagagagcag atctttactc atttcgttta ctgcctcaat caacgcagca
    19621 tttttagttt gactattggt cccagcggtt aattcactca tactcgctga cttatctaga
    19681 acaaaaacga tatcgattgg actgatttcc tttttctcgc ccccgatgac atctagatag
    19741 acattgtaaa gggttgttgc atcttcagga tgtagatcag atgctgtgct gcttggcaga
    19801 acaggttcta cccatttttt gatgtacgcc ccgttataat ccaagtaact gttttcaaaa
    19861 ttccgttcat ttccccaaag ctgaacggtt tgagctggaa cgtttctatc ttcttcgcct
    19921 gcagttgatc cattattagt agcatagtcg taatttcgcc agttcgctcc cccgtttgta
    19981 taatcactat catcgatcaa gttctctccg tcatatggcg agcctttgtc tccttgatag
    20041 cgttcattgc tttgtgtcca atttcctaac acttttgtat agtcattcgt tgtaaacttc
    20101 atctattctt tcatcaacca ccacttgaag aggtagttac ccttcgttca catcggggat
    20161 cttttctgtt tcaaaaatca atgtgccggt ttctgcttct tttgaataaa cttttccgac
    20221 ataccattct tgaccatcga tcgtctcgac ttttaggtct tctccatctt catcatagga
    20281 ggatagacct gttccacgaa cgttttttac ggtaccaatc ccggcggctg ccgcatcgat
    20341 tgctaaacgt attctacctt cattggcact ttcctttttt tcaaaagcca gatgccattc
    20401 aagggtttct tctttttcaa tatacttccc ttcaattttt gcatagtcct catctaagaa
    20461 tacctcatcc tcctttgttt ctgttgactc agcagctaca tccagggtcg tcatatgata
    20521 gactgactgg aaatatggtc caaatagcaa actgacagtt actaactgca aaagcttcaa
    20581 ttttaaccct ttcacatcct tatactcctt tcaaaaatat ttgtcttctt tcacaacaat
    20641 caacaaaaca atgcccatct aattataatt taatttaatt ttaattttaa atcaaatgat
    20701 atccttttta gttaaaaaac accaattata caacatttat tattaaaatt aaattataaa
    20761 attttataac gttctcattt aacaaaactt aagttattaa gacaaatgaa taaacaacta
    20821 cgctttcctc gaaacaaaaa aataaagcac aaatgcgcat ttacgcactc atgctttatt
    20881 cgtacaatta attcagataa cggcagcgca taggatgcca ataacacttc ctaaaatagc
    20941 tcctcctaaa atgtcagtag gataatgtaa aagtaaaaaa atcctcgaat aagcgatcaa
    21001 acaagcaaat aaaaaggcta atattcctgc aactggactt aattcgaaca acgcagctac
    21061 tgataaaaag gctagcgctg tatgtcctga aggaaaagaa gaagtcttcg gtttacttgt
    21121 gtaaaggaca agccgacgat ttttttcata aggtcttttc cgtcttgtcg tttttttgat
    21181 aaaaagcaaa ccaacaaaaa aatagatcaa actgccgata agaatggcta gaccatattc
    21241 tctagtatca ggtatcaaga ctaaaacagc agcaaggagc aaccaaataa aaccaccatt
    21301 agagatatta ctgataaatt tcaaaaaatt gatttttcga ctatccgttt tccgttgctt
    21361 ggcgaacttg ttgataatac tatcatcgat tttagcaatc aaacgcaaca tgttattcct
    21421 cctttttaag aaccttttct tgcgtacgat ggataaaaag caggacttga aaataaaaca
    21481 agaaactgaa acctaataaa gcaaaataga ttggtcctgc aaaccagaat gcgacaagaa
    21541 ggatcaacgt gcctgccaaa tagaaaagcg cgcttttgaa atcattaaaa aacaagaaaa
    21601 atgcagtaat ccaagaagct tctttttgtt ccagttgaag caagattttg taactaaaga
    21661 gaagcgcgct taatagaagc aaaaacaacg tagtatacat caatgtatag ccaattcccc
    21721 caccccaata gcggaaaatc tgataatcga tcaatagaag aagaaaataa acacttgcta
    21781 aactatcttg ctttccataa agagagaagt tctcacgaaa ctttttccag aatagtgaac
    21841 cgagcttttt ctcttcattt tttttgtaat gataaatcat atacagaact gttcgacttg
    21901 cagttcctaa tgtgaaaaca ggcaagacgc acaggaacca tagtagctgt aaatggataa
    21961 gacgtggaat ccattcaatg atttctaaga aataatcatt ggctttttta ccaatcgatc
    22021 gattcatcat ccttttgaac ctcctgtcaa atccatccct tcaatgaaat aacgttgtgc
    22081 aaaaaagaac agcaaaatcg tcgggatcaa gacaagtgtt gctcctgcca tcagataatt
    22141 ccattgtgtc gttgcttggt tctgaaaaac ttgcaagcca atctgtaacg tgtatttttc
    22201 ttgatcttgg atatataaca gaggacctaa gaaatcattc caagctgcgt tgaaggaatt
    22261 gatcgcaatg gtaatcaagg caggtttcgt caatggaagc atcaaatgac tccaaatata
    22321 caaatgattc gctccgtcga tttcagcagc ttcgatcaat tcattattga tcgataagta
    22381 aaattgacgc atcagaaata tattgaacgc attgccgaag aacgatggaa cgatcagggg
    22441 caaataagta cctacccagc cgatcttgga gaataataca tattgaggga tcatcgttac
    22501 aaaccccggg atcatcatcg tagaaagaac caaagcaaac atcagctttt tcccaggaaa
    22561 atcaagcttc gcaaatccat aagcaataaa agaatttgaa aggacattac cgatcactac
    22621 tagcacagtg atgaataatg tatttcttgc atagcgccaa aaaggaaagg cggcaatcgt
    22681 atccagatag ttttcccata cgattttttc tgggaaaaag gtcggaggat aacgaacgat
    22741 ttcttccatt ggtttcaatg aagtaaacac catccaaagc aatggaatga tcaaaatgat
    22801 tcctattact gtcatgagga cataacttag tatttttttt gtttgccgat tcacactggt
    22861 ctttttgaaa taatccatca tttgccgtca cctccagaat aatagaccca cttaggtgca
    22921 agcttcaaat tgacaaacgt cagaaccaac acgatcagaa acaggatcat tgacatagcc
    22981 atcgcataac ccatatcaaa agctacgaac gccttgttcc acatatgcag attataaaaa
    23041 agcaaagaat ttgcaggtcc gcctgttcca tttttcgtca tgacataagc ttcttgaaaa
    23101 atttggaaag aaccgatcgt agaggtgatc acatcgtaaa aaataatagg agtgattaat
    23161 ggcaaagtaa tacttttgaa ctttccccaa acgcctgctc catcgatttc tgctgattca
    23221 tataaagatc taggaacatt ttgtaatgta gctaagtaaa gtagcattgc tcctccagaa
    23281 ctccatattt tcatcaaaat caacgcaggt ttcgtccatt gtggatcaaa cagccaagct
    23341 ggtccaggga tatggaacca gcccagaaat gtgttgatca atcctgcaga tggagaaagc
    23401 agctgcatcc ataagatgta gactgctact cctgataaga ctgccggtaa atagaaagct
    23461 gtacggaata cactgattcc tttgattttt tgattgagta ctgtggctaa aaacacactg
    23521 aaaatcgtcg tcagcggtac attgaagatg acgaaataaa cggtgttgta taacgatttc
    23581 caaaataaat catcgtgaac gaacattctt ttgaaatttg ctagaccaat gaaattcatc
    23641 ttggatgtca aattataatc ggtgaaacta ccaataactg aaaaaagcat aggccctagc
    23701 ataaatacca agaacccgat aataaaaggc gagataaata aataggccca tcttgcttct
    23761 tttttctttc ggatagataa acgcttcaaa ttttcttgcc tcctctgtac ctagacagtc
    23821 aaaaatggat tattgatttt gcttgactaa gttttctact gctttttgtg catctgccaa
    23881 tccttctttt ggtgattttg ttcctaaaag aatctggtca atctgttcat tcactaatgt
    23941 cgtgtaatcc ggagcatcta aaggaactgg tgtgatcacc gtatttttaa agttttcgtc
    24001 cgccatttga tagatcattt ttcctttatc cgttaggttg tcattattca ctaaattctc
    24061 attggctgtc ttgctcgcca tgatatcaaa acttttttcg ccgaattttt cttgtacttc
    24121 tggagaagaa agatatttga tgaattcata agaggcctca ggatcttttg ctccgtatgg
    24181 tacttccaag acgaatccgc caccccacga ccaatggcct gaaccttctt ctttttctgg
    24241 gagctgcatc acgccaaaat caaaatcatc cggtgcattt tccatcaaac tagagtaata
    24301 attgatattt tgggcacgca tggctactaa tccggaaata aatggatcag atacaccaga
    24361 cccaaattcg gcttctaatt tattgatcgt atttttccca taataatctt gccagtcttg
    24421 gatccactcc aaggcttcca ctttattttt agtatcaatc ttgacttttt catctttgtc
    24481 aaaccaacta gtcccgttat ctgcgtttag cgcccataca tcagccccta aattccataa
    24541 tggataaaaa ccgatgcgtg taaattcttt tccttctttt ttatctagtt tacgtgctgt
    24601 ttcttctaat tcatcccaag ttgtcggtag atcttgttca ctgattccag cttctttaaa
    24661 taacttttta ttataaaaaa tgacttgtgt atctgtattg aatgggatcg cataaggatc
    24721 accttcatat tctactgtat cccaaagctg cggataaaaa tccttagaag tgtctttttc
    24781 tacatatttg gagagattag ttgcttgctg tgcttctgct ctttgggcaa cggaatttat
    24841 gtcctgtaca ataacatcgg gtgcatttcc agctgttatt gcagataaag atttagtcca
    24901 gatgtcaccc catggctgat acttataatt tacatggatc tcgttttgtg attgattgaa
    24961 atcctcaatg atttcttcga tagcttcttt tcgtgcaccg gatccccaaa aggaccagaa
    25021 atcaatattt tttcttccat cacttgtttt ttcagaagaa tttgctgcac ttgaactggc
    25081 atcgcttgca ttacttgatc cgcatcctcc taataaaaac aatgctgaac ttgccagcaa
    25141 ccctgtaaac aataattttt tcatatttta cctccaaatt ttaatgtaac cgatgccggt
    25201 tttaatataa cgatatcatt ttgttctgaa aataacaatt tataaggtat gattctaaaa
    25261 aaattattaa tgataccaat actttatata attcgcgagc gctttctttg aattttttaa
    25321 tctttcgtag cagaatgaga atgtattaaa aatagattag gaggaatttt gatgtttaga
    25381 caccagaaag aattgcagtt tgaagcaaaa ccagatcgtc cgaatccatt aatcgcgaaa
    25441 tatctgcagg agctgatcgg cggccaatat ggcgagatga gtgtagctat gcagtacctg
    25501 ttccaaggct ggagctgccg aggagaagaa aaatataaag atatgctgat ggacattgca
    25561 acagaagaaa tcggccacgt ggaaatgttg gcgacaatgg ttgctcgttt attagagggt
    25621 gcgcctgttg aagatcaaga agcagcgatg caaaaagatc caacaatcgg tgccattatc
    25681 tctggaatga atccacagca cgcgatcgta gctggcttag gacctcgtcc tgctgacagc
    25741 gtgggcaatc catggagcgg tgcctatatc attgcgagtg gcaacttgtt agcagacttt
    25801 agagctaatt taaatgccga atcacaagga agacttcaag tagcacgtat ttacgaaatg
    25861 atcgatgatc gtggcgtaaa agatatgctg tctgttctcc ttgcaagaga tagctatcat
    25921 caaaatctat gggaatgtgc agtgaaagaa ttagaagaaa aagaaggttc aatcttagtc
    25981 ccaagtactt tcccgcgtga caaagaacga aaagacattg cttatgactt ctataacttc
    26041 tcagagggag accaaagtag tgaaggttct tgggctagtg gcaaagcact ggatggcgaa
    26101 ggcgaatatc aatggttgaa agaacctaag atcgaaggcg ctgcaccaaa attagaacca
    26161 gtaacaccaa aaatgtatgg gacacctcca ttcaagaaat aaatatctac ccgtagaaac
    26221 acccgttttt tgttccacac gctttgtgag caaaactgac taaagtcatt aatcataacc
    26281 acccttcaaa agggtggttt tctctagagc tataagctca aatcaccggc cagcgcctaa
    26341 agacgctggc tttcatattt tatgttcaag ccatattgcc tttgccagtt ttgcccacct
    26401 cttaaaaggt ttatgtacta ctccttagcc cttaaaagga tcgtcttact ctcgtacact
    26461 cagcttatct aacgcactat catgtttttc ttgttcttga atgtactttt tgatggtcgc
    26521 ttcattttgt cctacttttg tcacatagta tccttccacc caaaagtgtc gatacccaaa
    26581 tttatatttt agatttgcac aatctcttga tgatctcctg aatattggct cgatattgat
    26641 tataaattat ttttcttcta tactttggtg tgaatacaat gtggtattta cacatctact
    26701 ttgtacgggc taaactattt ccctttattg ctccacccgc atagcaagtg gttttgtatt
    26761 tcaatcgctc ggcgcgctca attaggtcta aagacaataa atctaaaaac ccgctgcttc
    26821 actgacagaa acaacgggtt ttcagaaaaa aatgaaatga aaaagatctc ttacggcaat
    26881 ctattttatt tttttgattt tttataaatg gaaaatgctt caagaagtcc aagaaataaa
    26941 gccgtataaa aacaagaacc tatgaaatct ttatttatta gatattcaac agaaatcccg
    27001 ataacactag ccaacaatat atttatcaga agtgtaaaat aaggatgctt tttatagaat
    27061 agaactagtg ttgttttcat agactctcct ttcttcatat ttccaattaa tcacaaattc
    27121 acggcattac tagaaaaatt aaaggggcgc agaagtggaa aaatactctt cgactttccc
    27181 tacaaaccag gccatcttgt gtttaataac tataccaaat ctaaggtacc tctaaatcta
    27241 aattccattt gtggcggtga cctccaattt ttaactcttc tatctcccat ccagtataca
    27301 taaccttgat acttcgacca cttatatatc gaacacacaa atacctatcc attgcaggag
    27361 tactacctaa cttagttgct acttgcatct aaataacagc tgaaaagata ggacttactc
    27421 ttagtaaagt atctgaacta ttaattttta aactatcatt tttatcctca actacatgca
    27481 catctgttgc aacttcactt tctgtctcat ccagataaat gattaaggaa tcgggaattg
    27541 caatatcttc agctgacgct ggaatagttg agctaaatta gtcatcatat ctttattata
    27601 aaataaccaa cagcaaaaaa tacaatgaaa aacaaacttg gaactaatgt atcattaata
    27661 aatgttgaaa aattcagcaa ctcattactg tatgatttta gcagcccaac caacatatac
    27721 cctataaaag ctaataagat ggttaggaat cctttagaat ttttactcat tcatagacac
    27781 ttccttaaat aacttttatt atagaaggta ttgtaaataa taatattgac aaaaagtgac
    27841 tcaaaataaa aaaaaactta cattatactg gaatgaactg tattgatagt gtacctaaaa
    27901 gctctactga cataagatcg tgtaatcggt aaagtaattt tattaattat acgggatgta
    27961 atcaattaga gaataaacta atcataaaag gtacttttac attcataatt gtcgctttga
    28021 gattctactt tggttcacta tctgacccaa ttgcacattt tcgatcatta caagtattgg
    28081 tgtcgttaga acaactaaat aaaaactagc ggtagatttt tcagaatcta tgctaatttc
    28141 tgtatggatg ttccagtgat ggcaaatttc tcttttcatt gtttttcttg tcgcatgata
    28201 tgcctttttg tgttattcag ttaaactata gaaattcttt cctagacaga tcttgatccc
    28261 aaattttacg tttttgagca tcgatatagt ttaaaatgac attactcata tctaaagagt
    28321 ttagattttt taggactaaa actgtcagtt gttctttttc ttctttctgt taaagtattg
    28381 tcgcgacttt tcgtatacgt taagatatgt cgtgaaaaaa caagttttgt gacacaaaaa
    28441 aacgaatgac ttgaggaaat cacctcaatc attcgtttaa aatgctatat attctttagt
    28501 ttaagatacg gaaattaatg ccatcgacca cactagtaga atgaacgaca tttacttggc
    28561 ctttttttaa tttcgttatg tttagcatat aaaaatatta tagagtttac ttacaatgct
    28621 taaaacatat actgtataat ctgatcaatt ttagccatgt cttgcaatgg taagttttct
    28681 atttttttga gttttcgttc cttaaaatca agagatttta attgtgtaat aattacttgt
    28741 ccttttatat ctagctcttc aggtaatgag taacgtgtcg gtaaattctt tatagtggaa
    28801 gtaattggac atatgaccga aaacattgtt ttacggttaa attcataacg agagacgact
    28861 agtcctggtc gtcttttttg aatttctttt cctacggagg gatcaaaatc aatccataca
    28921 atatcacctt ttttaggaat ataaattctt tcttctgaca ctataaaatt tctctccctt
    28981 caggagttaa atcttcccat tcgtctttct cataatactc ggcctcttcc ccaccactaa
    29041 atggatcttc aatttttgga actaacgtaa ttgttccatc atcagaatac acaacgatat
    29101 attcttggtt ttctgaaggt ttctttccgt tatcagaagg taaagttacc actacagaac
    29161 ttccttgtaa tctagatttt gtaacaagca ttatcatcac tcccttaata aaagtatact
    29221 atataacact aagtaacgca aaattcccct ttgtaaacta tctagaaaat tgttttgttt
    29281 aaagtatatc ttattggata taaatagaaa taaattgtag ccagttcatt ttttctttaa
    29341 ctaaaaaaat aatccaagaa acattgaacc tatggatcca aaagctaccc aaatactata
    29401 gctaaccccc cgctaccttc aattttgcag ataaaacgct ttgggagaaa atttcaaaga
    29461 caacaggcca tcctatcatg cccgattata aacaaaaagc tggctattcc ttttgctctg
    29521 acaaatttca attgggaaag ttcacgaaac tagcaggtga agaagtttca actgttcgga
    29581 tcaaagaatg cccgcttcaa atagaaacat tggttcaacg aatttcaact agacaagact
    29641 ttgctattgt agaacgtgag atcgtagcta tttttgtaga agaagggatt ttacatgatc
    29701 caactcatat caatgtggat aaatggcaac ctcttatcta taaattcaga gaatatacaa
    29761 ctgccaacca gtcgttaact ttgaatttta gattccaaga attcaaagag tcataatgat
    29821 aaacatcgtt aggtataaat aaaaaagact cgcagcacga gtaaaaaaca aatagaagct
    29881 atacattaga aaggtcgact gtgaccctat agatgcagta tatgcagctt atgagtattt
    29941 cttctgttct ctttgttttt gggatctgtg ctgaagtctt tttcgttttt tgccgctctt
    30001 tctttgaaaa atcgattatg ttataccttc tccattacta attcaggcat ctgctgagta
    30061 atgatttttc gcgcaaaaga aatatctgtt acccaaggtt cgatttgttc ttcagtcaag
    30121 acaagcggca ttcggtcatg gattggtgcg actgtgcggt taggttcagt agtcattatg
    30181 attgattctg ccattttttc atcctgatgg ctacgataaa aaccgccaat atacactatt
    30241 ttttccttat ttgaaaacat aaatttgtct ttttcttcat tccactcatt gggaaaacac
    30301 aacgattttg caaaaatggt tgatgaaagg tctttttttc ttctactgtc tctgcacggg
    30361 cattaatcat caattgtcct tttttaaatc cggtaaatcc ccacttcatg atttccggag
    30421 tgaggatgtt ttcttcctct tttcttaacg tcacaacaag atttgacgga aaaacttctc
    30481 cagctgctaa ttctgctgcc tgcttcggtt gtttcgtctg ggcttctcga taataattct
    30541 gaaggagctc tgactctaga tcaaaaaaat aacgaccaca catcctaatc cctcccaatc
    30601 tttttttcta tcatacactg caacaagaag ttcgcaccaa caaaacgctt tcaatttttg
    30661 tagaactaaa aaagttgtga caagtgacaa actctccagt gaatggtatt ctcctgccaa
    30721 ctcctcggtc acaagtcaca atattcaaca aacatgagaa gctgcttttt gaaattgttc
    30781 cttgtgactc ggagtgaaac ggcaggctta cgacctctgg gtaaacggtg ttcaaaagcc
    30841 agtttctcgg tattaagcca aatttatgca aaaatgtaga aagctatttt cacaaaattt
    30901 ttcttaatac tcgaaactaa gcgacttttt cacaacctct tccttaaacg gtgttcaaaa
    30961 gcttgcatct gcggtaataa gcccaaccaa acgaaaaata tgagcagcta tttttatttg
    31021 gctgttctta ttacttgatg cagggcagct ttttcacaac ctctccacta aacgatgttc
    31081 aatcagctaa ccttcggtat tagctcaaaa aacggcaaaa tatgaggaac tattttgccg
    31141 tttgtttctc taatactcag gtcaaagcgc tgatttcaca acctctaata cacggtgttc
    31201 cagaagtagc ttcttcgaaa aataagccga aatttcacaa aaatttgaga agcaattttc
    31261 gtaaattcct tcttatttct tgaagctgac cacttctgtc acaacctcta attattaaag
    31321 aaccttttgc gaagttaaca atctttcttt gatcaattga aaattctgcc taagtagtga
    31381 tagatcctgt gtgactttca acaataagat acttccctgg atttcagcaa tcaacgcttt
    31441 ggcttgacgg tctgcttctt catcggacag tttttcttca gaaagtgcca ggatattttg
    31501 tttcgtatac ttgacccatt gattgactaa ttctagtagc aacagacggt attcttcatc
    31561 cactgtactc aactcaataa tcaaattacc tacaggacag ccatgataag tgatctgtgt
    31621 ctcatgatca gcgaaaatcc agtccaacat ttcttctaat gcttcttctg gctgttttcc
    31681 agcatttaag atgtcttcga acaattctgt ctgccatacg tccatatgcg catggatcac
    31741 cgctagacaa acttcttttt ttgaagaaaa gtaataataa aattgacctt ttcctgtatc
    31801 agaagctgct agaatatctc ggattgacgt ttcatgatag ccttttttat aaataagatc
    31861 tttggtcgct tccaagatct tttcctttgt tttcaatgat attctccttt ttcatttctc
    31921 atagtcctat attatacagt aaattcatca ttttttcttc ttaatcgttt aaaaaagact
    31981 gtgccaaatt atctgacaca gccctcacta taaaactgtt ctcatatagc tagatgttca
    32041 ttgattcaag aactgcgagg acaaaagcaa ttcctatctt atgatagttg ctctaatact
    32101 tcctctgttg tcatcacttg atctgcaata aagccaaagt tcgtcaacgc tgcatccatt
    32161 gcttcttggc caggagcacc aattgcatct gtcgctacca caacattgaa tccactctct
    32221 accaattcac gcatatggga atcgctacac aagtttccgt tcattccacc aagaattact
    32281 gtgtcgattc cattttttct caattggagc gccaaatcat tgctttctgg tccaaagatt
    32341 ttatgaggag agctgatgat cgtattttca tccaaataag gtttcaattc ttcgataaaa
    32401 tcggctcctg aaccttcttc cactgattca tattgacttt ttctagcaaa catctgctgc
    32461 tcaagcatca tatgttctcc tgcaccgcca aattgccatt tatggtcatg tgggtaaaaa
    32521 taatgaggag aaataaagag tttgtatcct ttttcttttg cttgttttac catttcaatc
    32581 atattttcga tcgtattgta tttttctaag atatcttttg tcaaaccaaa gccaccgcct
    32641 gctggtttca agaactcgac ttgcgggtca gtgagaacta ctgctgtatt tttattattg
    32701 aacatggtgg attctccatt cgttatttat tttaatacat catttagagc ttcactcatt
    32761 gtcggatgag aatagatttg atctctcaat aacgtataag gaagttttcc attcatagct
    32821 agcgaaatca agttgatgac ttcatgagaa tcttccgcat agatacttgc ccctagaatc
    32881 aagtcagttt cagggtcgac taaaactttg aatacacctt taggatcttc taatacttgt
    32941 gctttaggga caccgcttgt catatacttg aataatttgt aattgacgcc ttgtgctttg
    33001 gcttgttttt ctgttaaacc tacattggat aaagtcggag tgataaatac actgtaaggc
    33061 acagctttcc ggttattcgt tgttcgttta ttctcgccct tcaactgatc cataatgatt
    33121 cgataatcat ctagagagat ataagtgaac tgcaatccgc ctttgacgtc tccaatcgcc
    33181 caaatgttgt ctgcatctgt acgaaggtat tcatccacag cgattgctcc gcgatctgtt
    33241 agtttaacat ctgtattttc taatccaagt gatgctgtac ttggttttct tccagttgca
    33301 gccaaaactt ttgacgcttg gattgttact tcttggccat cttctgtaaa ggtgacggca
    33361 gctgttgatt cttggtctgc tacttgatct acagatacac ctagatggaa ttcgattccc
    33421 gcatttgtca tgtcttctaa aatcatttgc gcgatatctt catcttcacg tggaagaaat
    33481 tcagaatggg catcaagaac gacaacttta gatccgtatt cattgaacat tgatgcaaat
    33541 tccaagccaa tatatccagc cccgatgatc actaattttt ccggtaattg ttcctgatcc
    33601 atcgcttgcg tagaatcaat caagtagcga cttgtattca atcctttgat tggtaaaatg
    33661 attggttcag aaccagtatt gatgaaaatc cgttcgcctt caacaatcac tttttcacca
    33721 ttattcgtca cttcgatttg atggttagaa agaaaacgtg ctgtaccgtc catcactgtc
    33781 ccagttgcct catcgctgat catatgataa tttttggcgc gaagcatgcc cgtcaatttt
    33841 tctttccgag caacagcctc tgtaaagtcg attcctcttt ctccattgaa aatcaatgat
    33901 ttagaaggaa tacagccgat gttgatacat gttccgccat acatacgtgt tgacttttca
    33961 acgactaaaa ccgattcacc ttttgaagct aacgccttcg ctaaagtctt accgcccttt
    34021 ccaaaaccga tcacaatatt ttgatatttt tccatcattt ttccctcgct tcttttttac
    34081 ctaccgattg gtacaaaaat atgataaccg ataattgtct attctccaaa tcatctgctt
    34141 tatttgtcaa aaaaaaccag acaaaaagcg gtcctttcac gtttttagtc tggttcgatt
    34201 tcctttattc ttctaaacaa tcgttacttc tacatcgata tttcctctag ttgctttgga
    34261 gtaagggcag aattcatgcg catcttctgc aattttttgg gcttcttctt cgctgatgcc
    34321 atcgatatgc acttctaata ctacaccgat ctgatagccg ccatcatcta aattataaag
    34381 agagacacgt gcttttactg tggactctgc tgtcattcct gcttctttga tcatatgttg
    34441 taccgcccca ttgaaacaag aagcataacc tgctgcaaat aattgttctg gatttgttcc
    34501 ttctgcatgg attcctggag gagtgatttt catatgcatc gagccatttg gtgcctcgac
    34561 ttctccattg cgcccgccat ggttgatcat tgctgtttcg tatgcttttt tcattgtact
    34621 gctcctttcg attgaccatt tgctacttgg ctataattat agtgtatgac aagtaaggcg
    34681 ctttctacaa aaattctgct tattcgaata ccagaatgcc gtcttctact atttttccaa
    34741 aaaacaaaaa aatactactc gtgaacaaca gcgtcatatt tgttccaaaa taaatagcaa
    34801 tcttttctac ataatctttt atatgattga ttttaagata catatatacc agaaagttga
    34861 ccccataaac caatactgtt aaaaaaataa ccatattcgt taccattttt tcctcctttt
    34921 gctggtctcc ctaccagcac tcgatttaac cataccactt tttttgccgt ccaagcaact
    34981 agcctttcaa aaagactggt ttattctgct gttaatgatt caagatcaga aaaatgtccg
    35041 aataattttg ctaattttac taacgccaac ttgttctttc cgaattcatc attttctatc
    35101 tgtaatacta gtaacggctc atgtaagctt aaacggatca aaaaccagcc gtttccgtat
    35161 ggctcttcta gatcatatcg aataccttct tcattttccg ggtcgaagtt catccctttt
    35221 tcttcttcca acagtcgctt catttcttct aatatcttgt ttccttgttc gcgtggttca
    35281 tcgctgaaca attttaatcg gatttcttgt acttctacgg gctgtttcaa ctctttgatt
    35341 tgttcatcta atgtgatacc ttttcttttt aattctggca aaagcatcag gatctttgcg
    35401 atgacatatg caccatcatc cagaaaatag ttttccttga atgcagcgtg tccgcttgtt
    35461 tcgatggcta gctgtgtatc tttcccaaga cggttaagtt ctaatgcttt attgattaca
    35521 tttcgatagc cggaaatata acgaacttgg atgcctcctt tttcttcaat gaatctttgt
    35581 agatgagaag aagtagggga attcgtcacg attcttgttc ctggatgctc ttttaatacg
    35641 attgtactta atactgcgat caaattattt cgattgatca ctgttccaga agcactgaca
    35701 actgcagaac gatccacatc tgtatcgaaa atgatcccaa gatctgcttc atttgctaaa
    35761 acagcctgct tgatactttc catcgcttct ttattatcag gatttgggat atgattagga
    35821 aatcggccat ctggttccaa aaattgggaa cctgttgaat ccgcacctaa gctattcaat
    35881 actttttcag caaagaatcc accagcacca tttccggcat caacaatgat tttccaacca
    35941 tttagtggtt tgctttctag tgttccaatc ccctttttaa tttttgtgac taaatcttgc
    36001 gcataaggtg tcaaaaggtc tgctttttct acgcttccag tttgttcgct ttttattttt
    36061 tgctgctgtg ataggataaa agcaatatct tctttttctg ctcctccttc tgaggtaaag
    36121 aattttattc cattataata atagggaaga tggctagcag tcagcataac cgcagcatcg
    36181 cacgagaact gttcaaattg agtggacata aacatagcag gcgtagtagc taattcgaaa
    36241 tcgatgacat gtatcccttg ttctttcaga ctttggatca acgcctcttt cagtgctggt
    36301 ccgcttatcc tactgtcatg accaatccca atcgtccatt ttttatttgg atcggttgat
    36361 ttcttctttt tctttatcca gtttgctagt ccccagccga tcttttttac catgtctgtc
    36421 gtcaagttta cttcatatcc ttcaactggt aatgcgattc ctcgaatatc cgatccattt
    36481 tgcagcgctt tcatatcttt catataaaag tcctcctcat ttattccctc attttttcca
    36541 gcttttctgc aaatcgctgt gcttcttctt ctgagcggca aataataatg aatgtatcta
    36601 caccggccat cgttccgaca acttcagggt aagccacttc atctagccaa ttcgttacca
    36661 catcggcacc atttcgttca gtcaatacga taaccatgaa ctgaacagac tggatacgca
    36721 aaacctcgcg tctaattgct gtacgcaaac gttcttcatt taaagaaaca gatggctggt
    36781 taaataatgt atagcgtact attttgtttt cattttgact ttttactaac ttcatttctc
    36841 gaatgtctcg agaaatcgtt gcttgagtca catcggcgcc tgcttcatgc agccgcgcaa
    36901 gcagctcttc ctgtgtccca ataggttgtt ctgtaatgat ctggcggatc agtgcttgtc
    36961 gctgtttctt tttcatatta gacacctctc aatgttgatt atagcaaaag ataagtaata
    37021 tttcttcata ttttggtatt ttttactttt attttttgtt ttcattcagg ttgctaacct
    37081 ttttctattt taacacgcaa aatcgtcttc attttttcag gtgctgattt tcttggatcg
    37141 ctgatgtaaa tctctttgtg ttctttagaa gctctttcat agccttcttt tgcgatgaat
    37201 gcttctaatt tctcaaacgt tgctggttct tcggcatagg gcccgacgtg taagatttgg
    37261 gcacaaagac cttcttccat ctttttgaat actacttgtt ctttcaagtc ttccggaagt
    37321 ttgctagaac gctgaatggc ttcttgtgct atcgcttctg taacaaagtc aggctgtcgg
    37381 atcatcaatt gataagaaaa atgttctttt ttcatcactg gttcatgcaa atacttttct
    37441 tgcagtcccc attgtccttc cagtggatag acagtataca tctgataatc aggaatcagc
    37501 caattttttt taggcgacat gcgtattgca tagctgactg catatagaca ggctactctt
    37561 cgtttaaagt cttcctgatt cgggtcgccg atccctctga tgctaaagaa tgatttttta
    37621 ggaacctcta gtatttgcgg gctttttttc atactatagc tcttgtcttt acgccattca
    37681 attttttcca tttttcttcc tccgcgaaat tccatttagt tatttattat catacctctt
    37741 tttgagtgac ttggctaatc gtgttgacac tatttttcag tttgtgctag aataagtgaa
    37801 gtaaataaat cgtacagata acacgtttcg gcgtgtcgag agagaggcgg tttctatttt
    37861 tataatagaa atcactctct ttttttacga aattttttag aggtgatgta aatgacaaaa
    37921 caaaaacagc tgcttttagt acctgcagta attgcaacag ggatgatgtc ttttgcgggc
    37981 gtattgatcg agacggccat gaatgtaact ttcccaactc ttatcagaca gtttgattta
    38041 acgactgcac aagtccaatg ggtaacaacg atttatcttt tgatgatttc gatcattgtt
    38101 ccgctgtcta cttatttgaa tcgcaatttt agtctcaaaa aactcttttt agcttcaaat
    38161 ctgcttttct tggcaggtat aatgatcgat ttcttctctc ctaccttcat ggtcctattg
    38221 tttggtcgat tgctccaagg tgcagcgaca ggtatcgctc ttccgttgat gttccatatt
    38281 atcttgacat ttgcccccct caatcgacga ggcgcgatga tgggtgtcgg tactttgaca
    38341 acggccattg ctccagcaat tggccccact tatggaggca ttatgacttc acattttaca
    38401 tggaatcata tcttcctgtt tcttgtgccc gttttgattc tttctttgat tatcggctgg
    38461 tttgctattc ccgagatggc agtacaaaaa agtggttatt tggattggat aagcgtttta
    38521 ggaatttgtc ttttgtttag tggaagtcta acatttttga gtacgttggg aacagtttcc
    38581 agctggattg ctttaatcat cggcggtatt ggctggttcc ttttttacta tcgaagtaaa
    38641 aaagtggagc atccactgat ccgactgtct attctttcaa ataaaacatt ccgcttgttt
    38701 ttgattggct tcttagttta tcagttttta ttacttggtg tatcttttgt cttgccgaat
    38761 ttccttcaga tcgttcaagg aagtagtcct tttgtcgctg gattagcgat gcttcccggc
    38821 gcagcggttg gtgctttgct ttctcctttt tccgggaaaa tgctggatca atatggtccg
    38881 aagaagccaa tttttgctgg gctgattctt tctttgattg gttggctagc attattccta
    38941 ctcataggac acgcttcagt gggtgtattg attgcttgtc atgtgtttta tatgatcggt
    39001 atcggattat cttacagcaa tatgatgacc accggaatga atgcactgaa tgaagaacta
    39061 caaggagacg ggaacgcaat gttcaatacc ttgcagcagt tttctggcgc tgtggctact
    39121 tcattagtag cggtcattat caattacgtc cagcatcata cttcccataa ctatgaagtg
    39181 tctactacat taggatcaaa agcagcatta ggcgtcttgt tgctgttgct tctcgtaagc
    39241 tttgctcgat tcgcctatta tctgttcttt gctaaaaaag cgtagattcc atatacggca
    39301 ggtgttgcat ctgccgtttt tttgtgtgaa aatggttgtt tgtaaaagga ggctttttta
    39361 tggaaaaaat tgccattatc ggtggcggga tcattggtat gaccctagcc agttacttag
    39421 atacatcaaa attcaatgtt gctttatttg atgaagggac aggacaggca actaaagcta
    39481 gcgctgggat tatctcccct tggttgtcga aacgcagaaa caaacaatgg tatcgtctgg
    39541 ctaaagacgg cgctgctttt ttccctaaac ttataaaaga tttccaactt gatcaaacga
    39601 tttacgcaca atcagggaca cttttgcttc gacctgaaaa agatttagct gaattggctg
    39661 ttcttgccga gaaacgaaaa gaagaagcgc cagaaattgg aaacatcgaa tggctttcac
    39721 ctgaacagac atctcaagca cttccgttat tgaaaccagc agtttcactg cgtatcagtg
    39781 gtggtggtcg tctggatgga aaagcatatt tagaacatct tggtcagcgt ttagcacaaa
    39841 aacaaatgga gcagatccag gcaaaagtca ctttgcataa gaagagcgat tcttggctca
    39901 tcaagggacc gtttggagaa tacacagctg atcgtgtaat tttgacacct ggcccggcac
    39961 ttaagccttt attacaagaa ttaggctatg ctgcagatat acgtccgcaa aaagggcagc
    40021 tcttagcatt tcagacatct tataagatga gtcaagactg gcctgttgct atgcttgacg
    40081 gagaagctga tttcattcct ttcatggatg gaaagatcct tttaggtgct acccatgaaa
    40141 acgatcaagg ctgggatttg gctcctacta gcgaagctta taagggattg actaagagta
    40201 cagaacagtt cttgactgat ccagatcaga taaaaaactg gccatacgag ttccgtgtag
    40261 gtacccgtgc ttatacgtca gatttttccc catttttcgg cgtactgcca gatgatccaa
    40321 gcttactggc tgctagcggt ctaggctctt ctggcttgac cacaggtcct tatatcggct
    40381 atctattagc caacttctta aatactggtc attggcctac ggaagattat caaaaggaca
    40441 tctccaccta tattacgaaa aatccatcat agaaaaacag ctttttcaag taaggatccc
    40501 gagcgatatt gcgcatggat tacttcttga aaaagctgtt attttagttc aatttctgaa
    40561 tcaaattctc caaactttct tttgcttcat ctggcaagag atcttttcct atctgagctt
    40621 caatgaatcg taaacgaata tcaagtcgtt gtttcaccag atttttatag gacgtatcct
    40681 caaaagaaac aggaaaatct ggtataggta aatagtggat gtcttcaaat ggaccaaacg
    40741 acttgaattc tgccgtttgt tgcacgattc tttcaacgat tgacaatgtc gtttcaggtt
    40801 tgattttttt atcatcgaaa tatccagtat tcaggacata gcaggctgtt tgctgtttca
    40861 aaaacaactc tcgaaaagct tgatagtctt ccctaagagg atagacacgg aaaggattag
    40921 caaatggttc aatgactagc tcatctagct gtctttttgt agtgatattt tccgcgtctg
    40981 atcgttttgt tgctaatgtt gcaccaaaag acgctgctaa aactgggtca ttgatcttga
    41041 taattggcgg aagcgaatca tctttcatga tccaaaaaac agcatcgatc ttttcgctaa
    41101 gatgatcgac tcggtcgggt gtcgcataac gtgatttgac tgtccgccca tttccgtttc
    41161 gtatatctcc tgttactagg actttttctc ctttacttgt acatgtcacg cccacattct
    41221 gacaagtaag gaaagaagaa atggccggat catcagacgg atagtcttgt gttttatcaa
    41281 agtaagaagg ttccaaggca gtagcaaaac cattttttcg agaaataacg aaagcatcgt
    41341 catgcaagat cgaaacagag tgaccttccg tatgttttgc taaggtaatc gttgattttc
    41401 cagaaccgga caacccaaat acagccatcg tataggtctg gtcattacta gcatattgtt
    41461 tcatcccacc gtggcaggca ataaagccat tgcgatttcc caatgcccaa gcaagcgtca
    41521 aagtcgcttt ttttaattct ccaaagtaac gtaatcctag cacaaccgct gtattatgga
    41581 gagcatcaaa caaaatgagt ccatttggaa atgtttcatg tgtccattcg ggatcacaaa
    41641 agatataaag atctccctca tcaaaggaaa cagacttttg ataagtctct aagatcttcg
    41701 aattcgctgg ctgaaaattc agcaaataag aatacaaatt gttctcaaat ccttctggaa
    41761 tcagcaaatg actttgcaca gaaaattctt cagataggcc aacgattact tttgtatggt
    41821 aaaactggcg cttgcgactt tgatacacag cttctcttaa aattttctcg tatttgcttt
    41881 gttccttgtc taagtcctca aagatccgcc gagcacttgc tgttcttccc acaatgcttc
    41941 catcattgaa tactagtgtc ctaacatcag ctggtaaatc tagttcttca gcatgtgaga
    42001 ttgttaaatc tgtgatgatc gttcctggac tcccttttgc tagttgataa gctgtcttcc
    42061 tatcaaaaac ttcatgaaca ttattaccgt aaaatgtcgt ttctacaatc gatcgaatac
    42121 tggataacag tggatttcca cttgtgattt cgtttaattc gagactctct tttgtactca
    42181 tggctcctcc tcattcccta aacaaaaaaa cgttttcttt attatacatt attcgagttt
    42241 ttatttgtac tgctgcgctg tgggaagcaa acgagttatt tttcacacaa aaaaaccgag
    42301 aacttgaata aacaagtttc tcggtttcat cattttcctt ttatcggctt agtaccagcc
    42361 gtttgctaac cagaatgttt tagcagcatc ccatgaacca taacgagatg ttacatattg
    42421 ttctgctaca cgttcttgat tggcagctga atagtcgccg tttaagtatg aagcatctaa
    42481 ttgataacgg ccgatgtaac gtccgttagt agctgtgtat gaaccgcctg attctttttg
    42541 tgcgatccat tcttttgcag agcttgaagt tggcgctgtt gcagcagctg gggcagcagg
    42601 agctacttca actgtttcaa caggtgcaac gtatgtatgt tcttgcgttg ctgtttcagt
    42661 tgtagatgct gtattttctg ttgttttgtt ttctgttgtt gctgaagaat catttgaagt
    42721 tgggattgtt aattgttcac caacataaat gcggttgatg tttgcgatcg aatttttttc
    42781 agcaattgca tcgatcattg agttgtctcc tgcaaatttt tgtgagatct tagataatga
    42841 atcacctgat tttactgtat aaacttcatc agcgtgagca tttgtagttc ctacaaacat
    42901 tgcagtagca ccagcagcaa aagttgtacc taaaacaatt ttcttaaatg aattcatatt
    42961 aaactccttt ttttctccgt tttttattct ttcgacgcta ttaactttat catttagaaa
    43021 tatttcatag gtaaaagaaa catgacattt aatgacaaaa taacgaatta tttaatattt
    43081 gtaacattta aacaaatatt tttttgatac aaaaccataa aagccttgtt gtataagcaa
    43141 agtaatcgtt tttctatgtt tttttatttt tgaatgaaaa acgcagattc tgtaacattc
    43201 actgcaataa tccataaaaa aaagcaaaaa aatttttgat ttttatcaaa ttctcttaaa
    43261 aaaatgtaaa aaatacaaaa aaaccagtaa ttgttacaac aattactgga caaaaacttt
    43321 gaataatgtt aactattttt ttattttaac tttctccgca ataatttctg ggcatgttcc
    43381 aattcgttta taacgacttc ttctgtttct ttagctaata tttcatctaa tacatcaagc
    43441 catttttccg gttcttttgt tcctagacgt ccaatagccc aagctgctgt tcctctgatg
    43501 acagggcgga catctgttaa acattctgaa atctcaggca atgccgttcg atcacctaga
    43561 ttagctaaag caatcaatgc gtttctctgc aaaggtttct tcccacgcca tgaaccagct
    43621 aaatgcccaa attgctgttt gaagtcttta ttagacatcg aaagcattgg ctttaatttt
    43681 ggatatattt cgtctacttt tggttccatc tcttcatgaa aatgaaaatc ttttccttga
    43741 ttgtaagggc agactaactg gcagatatca catccataaa tgacatttcg cattttttta
    43801 cgatattctt ccggcatcat cccttttgtc tgagtttgat aagacaaaca tcgctgggca
    43861 ttcattcttc cgtcaccaag caatgctttt gtcggacaag cagtcacgca gcgcatacag
    43921 tcaccgcaac caaattctcc tggtttatca ggctcaaata caatattagt aacgatctca
    43981 ccaagataga caaatgaacc gaactcttca gtgatcaaca atccgtttcg tccaataaat
    44041 cctaaaccag ctcgctgtgc tacagcgaca tcgatcagtt ctccagtatc tacttgcgga
    44101 gctagacgcc attcctcttc tttttgccat ttttctgctc ttgtttggat gaattcgatc
    44161 aatcggttca aacggtctct gagtatatca tggtaatcga tcccccaaga agcacgagca
    44221 aactgcccgc gtttttcatc cctaggcact tcttcatgga tcctagtagg atacgcaagt
    44281 gcaatggaaa tgatcgattt cggctgatca aatgtcattt ctggataaag acgctcatcg
    44341 atatttggat gttcaaagcc agaagtatgg ccagctgctt tttgttcttc caacgattct
    44401 tttaatgaat caaaaggttc cgccgtggtg aacccgattt tgtcaattcc taatcgtttg
    44461 ctttcttgta tgatttcttc ttttaatgtc atggtcttcc tcgcttgctg ttaacggctg
    44521 tataacccat aatatagttt ttcttttttc agctggacaa actggatctg ctgatcggca
    44581 atcttctttt cttccatcca tttttttctt gcagcaaata cttcccaata atttgttgaa
    44641 attaattttc ttttgttatc taatgcatta aaaaaattca atgaaactgg ttttgtactt
    44701 aacagttcat ggagccttac ctcttcccat ggcgaaaact cagacagatc gcgggaatac
    44761 aatacttctt catagagatt tttttgctgt gtgtacgtga atgtttgcgg gattttccca
    44821 ggcctagcaa tttctactag acgattataa aacatattca ttaatttgct gttggcaata
    44881 aattgacttt tataataggc cgactggatc tttttgatta ctccttctgc tttgatgact
    44941 gaaaataatg caggccatgc tttgacggtt atttcgtcgt tttgtttaac taatacgcca
    45001 ggtgtgaagc cgactggaga aaggaacaca aaataaccga taccggtatt ttcatctaaa
    45061 ggctgaaatt catcaaacaa ccatttgcct atgtacagct cttcatctgg ttctgttgtc
    45121 tcattttgat ttgctatgaa taatttagct aattctgctt caagaaattg aaggtcttga
    45181 tccttgtcgg tattttcctg ctggctgatc aatcgaaaga cttcttcttt aatcgtatat
    45241 ttatctttac gtgtaaaatt catagccaca ccttccttcc ttactctaac tataacggaa
    45301 tttcttcaaa aaaggtatct gtacgacgaa aaacagcata attttttttc atatctctta
    45361 taaaaaatgc aaggtctgct cctcaagcta gaccttgcac ttttcagctt tcttttgttt
    45421 gtgacaaacc ttcatggatc gtttcaatat tccatttcat catctgatag taagaatctc
    45481 cttgttctcc ttcttttgct atggaatcag tgaacagttt atcatagatt ttcaaacccg
    45541 tttcttttgc tacccgttcc atgcttcttg agtctacact ggtttccacg aataaaaccg
    45601 gtacttcttt tgctcttatc tgatcaatga tcgctttcat ttgatcaggc gtaccttgac
    45661 tttctgtatt gatctcccat atataagctg ctggcaaatc atatgctcgt gaaaaatact
    45721 tgaatgcccc ttcacttgtt actaataatt ttttgttctc ttcgatagaa gcaaaacttt
    45781 ccttcgcttg tgtatctaat tcttttagtt tttccacata tgcttctgca ttttttttat
    45841 agagtgtcgc attttctgca tctttttcag agaatatacg tgcgatttcc tccacatatt
    45901 ttattccgtt agataggtct agccaagcat ggggatctgc ttttgtatgt tcttcaccgc
    45961 tagttaaata aagaggttct acatttttgc taactgcaaa ataatctttt ccttcttctt
    46021 ttttagccgt ttccatcaag ttatcgaacc agctgttacc tgtttcaaga ttcaaaccgt
    46081 tgtataaaat aacatctgca tcgcttgcct ttttgatgtc ttctggtagt acttcatatt
    46141 catgcggatc tgttccgact ggtacgatac tgtggatatc tatttgatct gttccgacct
    46201 cttttgccat gtccgccaag atcgaattgg tagccacgac tgacaacttt tctttacttc
    46261 cttcatccgc ttggtcagaa gcctgctttc cgcaaccggc taataccaag aaactaactg
    46321 ccaagattaa aaagagtgat ttttttgttt tcatctatct gcttcctttc tgaaataaaa
    46381 ttccttttgt tggagaaaat aaaaaagcaa ggataaaaaa tgcggtacat gctaacacga
    46441 tcgtagctcc tgatggccaa ttgtaactat aactgaaaaa cacaccgaca actgcactta
    46501 gcataccgat tcctgcagct gtaatgatca ttttcagtaa atggttcgtt agcaagtaag
    46561 ccgtggcggc tggtgtgatc aacatggcaa tcaccaagat tgttcctact gtctgtaaac
    46621 tgactacagc cactaatgtc aaaaagaaca tcaaaagata atggatcagc gatgtgttca
    46681 gcccataagc ttttgccatt gtcggatcga atgatgtgat cttcaattct ttataaaaga
    46741 aaaagacaaa tatcaagacg attccactaa cgagtgctgt cagcaacaaa tcgctttccc
    46801 taacagctaa gacattccca aataaaatat gatacaaatc tgtcgcactc tgggcatatg
    46861 aaatcaagat aatccctaat gcaaaaaagg agctaaagac aattccaatc gctgtatcat
    46921 ttttcaatcg gctccgctga gtcacgaaac caatcactgc tgctgttagc atcccaaaag
    46981 cagtggctcc aaagatgtaa ctaaaaccaa acatataaga aatggctaca cctggaagaa
    47041 ctgcgtgaga gatagcgtct cccatcaaag acatccctcg taaaataata aaagaaccga
    47101 tgactccaga agcaagtcct acaagcatgg aagtgaccaa agcgtattgc aggaattgat
    47161 aattcattaa tccatcaata aaggattgga tcattttttc tctcctcctt ttactaaatg
    47221 tctgatgatc tcaccatagg ccaattgaag gttcttcgat gtaaagactt cttgtactgg
    47281 accggaagcg atcagctgtt tatttaaaag aataacctca tcgaaatatt cttctacttt
    47341 atgaagatca tgatggacga tcaaaatcgt ttttcctgaa ttcttcaatt cctgcaagat
    47401 gtcaaagatc tttcgttcac ttaacgcatc aatccctacg aatggttcat ctaaaaagat
    47461 ccattctgct ccttgggcta gagctcttgc aataaaaact ctctgaagct gtccacccga
    47521 tagttcgctg atctgtcttt tggcatattc ttccatccct acttttttca aagcttgtct
    47581 tgcacgttct ttttcttttt tcccaggtct ttgtccaatt cgtaaagatg gatatgttcc
    47641 taaaagtaca acgcctaata catcaattgg aaaggaaaga tccaattcac ttcgctgttc
    47701 cacgtaggct atttttttac ggactgagtt taccgactgt ccagaaaagg tgactttacc
    47761 agtagtagct ggtatcaact ctagcaaaga tttcataaat gttgattttc ctgcaccgtt
    47821 tggtccgata ataccggtaa ttttttgtgg atttatcgtc aagttgatag ttttcaaaac
    47881 agttttccct tgataagcgg ctgaaaggtc ttgaattaca atggccgtac gttccaaatc
    47941 ttacactcct ttttaggttt acctaacttt ttatttaaat atagtttaac taaaatggaa
    48001 agcattttca agtagaatga tgaaaaagtt tttttcgaat tttcctcgca ttttatgaaa
    48061 attttctgta gaatcacatc aagagttcaa taaggctaac ctaataatga aaaacatgtg
    48121 ttgaaacgtt tgattatttt ttcttgttga ctcaacaacg aaaggagttt ttgtatggaa
    48181 gaagaaaagt taactcgaag tcttagtgcc cgtcatatcc aaatgatcgc actaggtgga
    48241 acgatcggtg tcggtctgtt tatgggtgcc tcctcaacca tacgttggac agggccctca
    48301 gtgatgggag cctatgcgat tgcaggattc tttttgtatt tgattatgcg tgctttaggc
    48361 gaaatgcttt acgttgatcc ttcgactggt tcttttgcaa attacgcgag cgagtacatc
    48421 catcctgtgg ctggctactt gaccgcttgg agtaatattt ttcaatatat tgtcgtagga
    48481 ataagtgaag tgattgctgt aggatcttat atgaattatt ggtggcctga tttgccggca
    48541 attattcccg gaatcattgt cgtcttgttt cttatgctgg caaatcttat ttctgtcaag
    48601 gcgtttggcg aattagaatt ttggttttcg atcatcaaag tcataacgat cattttgatg
    48661 atcattgcag gtcttggggt aatcttattt ggatttggta atcatggtca ggcagtaggg
    48721 atttcaaatc tttggaaaaa tggtggattc ttcactggag gcgtcaaagg atttttcttt
    48781 gcattatcga tcgttgttgc ttcctatcaa ggaatcgaac tgatcggaat gactgctggt
    48841 gaagcagaga atcctaaaaa gacgatcatt gaagctgtcc agtccactat cggtcgaatc
    48901 ttgatttttt atattggtgc tatttttatc attgtgagta tctatccgtg gaatcaattg
    48961 agtgagattg gttcaccttt tgtacaaact ttttctaaag tcggcattac atttgctgca
    49021 ggactgatta attttgtcgt gattacagcg gcattatcag gttgcaattc agggattttc
    49081 agcgcaagtc gtatggtcta tacacttgcc ataaatggaa agatgtctaa aaaatttctg
    49141 aaactatctc gtcacggtgc gcctttttat cctgtcgtag caatctcagg tggaatctta
    49201 attggtctga tcttaaatta tcttctacca atgttcatca accagtcaga aaatattttc
    49261 gttttcgtat acagctcaag tattttgcct ggtatggttc cttgggtagt gattttgatc
    49321 agcgagattc gcttcaaaaa gaagcacgca gataaaatgc atgatcatcc ttttaaaatg
    49381 ccactatctc cttatacgaa ttatgtgaca cttgcttttt tagctatcgt attgattttc
    49441 atgtttatca atcctgaaac gagaatctca ttgattattg gactcgtttt cttgctttac
    49501 atgacgatcc attactttgt acgcgaaaaa agaaccggaa aataaaaaaa gaacgaagct
    49561 tcaccttagt ggaagcttcg ttctttttta ttgcttttat caattcaatt ttagcgtctc
    49621 accgggagtc aggaaataat tctccatgct catcccattc agcgacaaga tcgtttctac
    49681 tggtacgcca gttcgttcgg ctatttgatt tggaccttct ccttccaaaa ctacggttgt
    49741 cgcagcctgt gaagtcgcgc tgttggtatt agtttcagag gaatctgttg tgtcttgtgt
    49801 tgttcgagct tgcatttcag aagcttctac cgactctgct gtctcagaat cagaagatgt
    49861 tgtgtcttgt gtgcttgttg actctgcttg aagagaggcg ctagtctgca aataaatatc
    49921 ggaaatctta gcgacatgat tcgtataatt agccgataat tgattgatca aagtatctaa
    49981 gtctacaccg tctttatttt ctgctgcctg atacgctgca cgtaattttc tgatcccttc
    50041 gtcggagatt gcttgaagct cacgtgcttt ttggttagca actgctgata aaccagctat
    50101 tccctcttga tttccctgaa tttctgtctg gtattcttca atcaatgcag gcgtcttttc
    50161 ttcgatcttt ttcgaataat catttacgat tgcttgaagt tgctctggca aaccatttgc
    50221 tgttttttct tcagaagttt gtgtctcttt tgttttagtt gatgactcac ttgtttgttt
    50281 cgtctctgtt ttctttgtcg ttgtttccgt tatggtcgta cttttcgctt ctgacgaatt
    50341 ttttccatga aaatatagac ccgcaactcc tcctgctatg atcaaaaaca cggcaactgc
    50401 tgccccaatc atgatcatcc gcttacgagc tgcttgtttt tgctgtcttc ttcgggtcat
    50461 ccgaacattt tctccccact cattttcatc atacattttt ttcaccacca atttttatgt
    50521 ataatagcgt tatcaaacgc ttcatattct tattgtagca aataattgtc gctgtgcaca
    50581 tttttatctt tgttatttat aagaaaattt caccagttga gatgattcca agattgtccg
    50641 tcgatttctc cttgcagctg cattgttcgt tcgtctatct cagccatcag tttctttatt
    50701 tcatataaga gcgcacggtc ttgatattct gatttttcgc ttaattcatc taattgttgg
    50761 atcagccaat catttgtcat aatgaagttc ctttcatttc ttgcagtgta aaggtcaagt
    50821 cttcgatctg ctcttttgcc tcagtcagtg cttctacgat atatgcttgt ttttcagatt
    50881 cttcttcctg cattttctga ttttcctgta ctctttgaat aaaccagtca atccgctgag
    50941 tcagcgatgg tttgccttcc aatgagagat actgctgata agcaattagc ttctcccaac
    51001 gtttttcctg ggataaatac ataaattgtg ctaaaacgaa tggcggaaga taggtcatat
    51061 ggaatttatt tgcgattcgc tgatacggcc tcaaaaattc ggaaatcgta tattcttctt
    51121 ttcctccagc ttggtattct ttttccgcca cacctgttgt caatacgatt cctagttctt
    51181 tcccttttaa tacatgtgct gctcgttcca agacattatc ttgccaaatt tttaaatgag
    51241 caggagaact ataccagtaa aacggaaact ggaaaatgat ccgatcatgc tgggccaaga
    51301 gctgtagttc agtctctata tctatttttc cgtctggata acttgattcc aaatgatgcc
    51361 aagtagctgg taaaccagca gaagcttctt tgaaaaattg ctgatttaaa gattcttcga
    51421 tcgttggatg gctaatgatg ataagtgtac gcatcccttt tcctcctttt tagtcttcgc
    51481 tttacagtgt agcataaccg ccacaagttt cttttgccga tgcttgtcat tttaaccaga
    51541 ctaatcaggt tgtccaagaa actgcggttt gtttttccaa ctgttttttc aaggtatcca
    51601 aagcaatatt cttaaaattt tcgtttttca tacgtttacg atagttcgta gccgtttctc
    51661 cggtactctt tttgaacatt cggctaaata cgactagact attgaaccct acttgatagg
    51721 caatactttc cacggattca tccgtcagag aaagaagaaa cgcccctcga ttgatccgta
    51781 ccccgatcaa atattccttg atactggtac ccatatgatt tttgaatact cgcgacaaat
    51841 ggctccgatt gaccgctaaa tgctgggcga tttcctcaac agacaatttt tcagcataat
    51901 gtgcctcgat gtatttgact gtttcaacag ctaaagagga atgaaccttt tgtacaccac
    51961 cgctgacctt tccgccatct tttaaaagga ctgataaaaa acggtaggtt aatgctgtta
    52021 actgtaattc attttccaag gtttcttccg tatctttcat gcattctaaa ataatgtcga
    52081 tatatttttg tatgtcagaa gagaccatcg tgtattggtc ttctctgaaa agcgactgcc
    52141 gaatgatttc ttctgcagca ctcccaccaa atgaaagcca gcaatacatc cacggatctt
    52201 ctccatctga taagtaaaac gtcgagtctc ctggacgaat caagaacaga tcaccttttt
    52261 tcaattggaa ttgttgattt ttcacatgat aagatccttt gccttccatc acgacatgca
    52321 ggatgtaatc attgcgaata gcaggaccaa aagaatgaaa cggcatcgtt ttagagaaac
    52381 cacaaaaatc aaaatacaat tctttttcta cttgttgatg ttcctttttt aaaaaaatcg
    52441 attgctccac gtctatccct ccttactcct ttagtataat gcaacaaaaa gttaaataaa
    52501 agtcacagaa atatattaaa aaggaagcga tttcttgtta agtttaagtc attaaaagat
    52561 ctttgttatt cgttgtaacc ggtttactta gtattatata ttgaacagga gaggaataca
    52621 gattatgaaa agcaaaatga tccaacgtgt gtcctacgct ttaggcgctt ttggacacga
    52681 cacattctat gttacattaa gcacttattt tatggtattc gtgacaagcc agatgttcgc
    52741 aggaacagat aaggcaacga atgcaaaaat gattgctaca gttacaagct tagttgtagg
    52801 tatccgctta gttgaaatta tttttgatcc tttgattggt ggcatcatcg ataatactcg
    52861 tacaaaatac ggtaaattca aaccatggtt agttatcggc ggcgttgtta gttccgtact
    52921 cttggtagca atctttacca atttctttgg cttagctact cataatacga ctttatttat
    52981 catattattt gcaatcgttt tcatcttatt ggatagtttt tattcattta aggatatcgc
    53041 tttttggtca atgattccag ctttgagtac ggaaacaaag gaacgtgaaa aatttgctac
    53101 gtttgctcgt ttcggctctt ctctaggtgc aaatggtact actctagtcg ttgtccctat
    53161 cgttactttc tttacctatc ttgttactca taaacatatt gaaggcgctt caggctggtt
    53221 ctggttcggt gtgattgctg ctgttatttc aggcggtact gcgattatca ctgccttggg
    53281 cacaaaagaa gtcgatactg cgatccgtca gcaaaatgaa aaagctggga tcaaagatgt
    53341 gttcaaagca gttgctcaaa atgatcagtt gatgtggctt gcccttgctt atatcgctta
    53401 tgcgattgcc aatgtagcaa caactgccgt attattctac ttcttcaaat atgtacttgg
    53461 ccaaccaact gaattttgga tcgttggtct agttgctgcc ttacttggtt tagtagctgt
    53521 tccactattc ccaatgctta cacgcgtcat ctctcgtcgc tacgtttacc ttggagggat
    53581 cgcaatgatg atttcttctt actttttctt tacgatcgca ggttcaagtt tgccaatcgt
    53641 tatcatcggg ctagtattgt tctacttccc tcaacaattg attttcttat ccgctttgat
    53701 gacgatcaca gactctgttg aatatggtca atggaaaaat ggtatccgta acgaagctgt
    53761 tactctatca attcgccctt tactagataa aatcgctggt gctttgtcta acgggatcgt
    53821 agggtttgtc gctatcgctt ctgggatgac tggtaatgct actgctgctg atatcactgc
    53881 tcatggcgta acgactttca aagcttatgc attctatgct cctgctgctt tgatgatttt
    53941 ctccgctatt atttttgctt ggaagattac attgacagag aaaaaacatg cacaaatcgt
    54001 tgagaaattg gaaaacaaat tggctccagc tgatacaatg gaagatgaac ttcacgatgc
    54061 agtagttcct tcccattaag aaaggatctt gaaaatgaag attacagaaa aagattttgg
    54121 ccaaggttat cacttgataa ccttggagaa caaaaacaag ctagcacttt ctatctctga
    54181 tttaggtgct agaatcgtca gtttaaaatc aaatgatcga gaattagttt tgggatttga
    54241 caccgctgaa gaatatatcg aaaaagatcc gtatatcggt gcttctatcg gtcgcaccgc
    54301 agggagaatc gaaaatggcc acttttctct caatggaaaa acttaccaat tagccacaga
    54361 tccaaaaact ggacataatc tgcatggtgg tgctcctgga tttgaattaa aaaaatggtc
    54421 ttatgtcatt ttgaatggcg aaaatgaagc ttctgtcatt tttactacta caagtcccga
    54481 cggagaacat ggttttccag gtacaatgga tgtggaaatc cgctatactt tgacaaaaga
    54541 taatatctgg cgagtgacct ctcgcggcac cagtgaccaa gatactttat tcaatccgac
    54601 aaatcatgtt tacttcaact tgacgggaga tgcttctcag tcaatcgatc aacatgagct
    54661 ttggctcaat agcgaagctt atgctccttt gcgaacagat agtattccta taggggtaaa
    54721 agaaaatgct gcaggaagtg ctttcgattt tcaaatacct aaaaaattag cgtccgtttt
    54781 tgctagtgat ttggatcaaa aaaatcttgt tgacggaatc gatcatccat ttttcttaaa
    54841 agaaaccggc ttgggtaaag aagccgctcg cttgactagc cccgataaaa gaatccaagt
    54901 agatattgct acagatgctt ctagtgtggt tattttcact gcaaatttcg gcacagaaac
    54961 accagaaatg cgcaaccgaa aactggcaca tcacggtggc atcacatttg agactcaaac
    55021 agctccaggt gcagagcgct tctcagcatt tggttcgatt catttaaaag ccggatcagt
    55081 atttgaaaca gtgacagaat tcaaaatcaa aacaagaaag gaataactca tcatggaaat
    55141 caaaagaagc ttaaacacaa aatttgccga aacattcgga cctaaaaaaa ctacacaata
    55201 cttctcacca ggacgcatca atttgattgg tgaacacaca gattacaatg gaggccatgt
    55261 cttccccgct tccatcactt atggaacgca aggtgtagca gcacctcgag acgataataa
    55321 aatattagtt tattccacaa actttgacga tatcggtgtc attagtttta ctttagatga
    55381 gctagaatat gataaaaaag caaactgggc aaattacgta aaaggaatgg tccttaaatt
    55441 aaaagaagct ggacactcaa tcgatcatgg gtttgagtta ttagtggaag gaacaatccc
    55501 taatggtgca ggactttcca gtagcgcttc attagaatta ttagtaggtg ttgtattaga
    55561 agatctgttt gatttaaaaa cagatcgctt ggaactagtc caaacaggta aaaaagtaga
    55621 aaatgaattc atcggtgtca attcaggtat catggatcag tttgccatcg gcttcggtga
    55681 gctagatcat gcaatcttat tagatacaaa tacgctgaaa tacgaaatgg ttccagtgaa
    55741 actagatggt tatgcaatcg tcatcatgaa tacgaataag cggcgggaat tggcagattc
    55801 aaaatacaat gaacgccgta gcgaatgcga agaagccttg gcacgtttgc aaaaaacttt
    55861 gcctatctct tctttaggag acttagatga agaagaattt gaatcaacta ttgaccaaat
    55921 cggcgatgat acattgatac gcagagctcg ccatgccgtt tctgaaaatc agcggacttt
    55981 gaaggcaaaa gctgaattag aagctgggaa cttagaagca tttggtcaac tgttaaatga
    56041 ttctcaccac tctcttcgct atgattatga agtaactggg atcgaattag atacactagt
    56101 agatgctgct caaaaacaag aaggtgtctt aggtgcacga atgacaggag ctggatttgg
    56161 tggctgtgcg attgctcttg tcaaagaaga aaatatacct gccttcaaaa acaatgtcta
    56221 tgatgaatac atgaaagttg tcggctatgc tccggaattt tatgttgcac acattggaaa
    56281 tgggacaaca aagatcgatc cagaagctgt tcatgtttga taaaaaaatc aacgatctca
    56341 gctaaaaaca aatagataaa aataacctct cagcaatttc caaatgtgag ccttttgctc
    56401 gtatttgaaa attgctgttt tttattgaca cggaaagaga acgtgtgttc taattgtgtt
    56461 gaagaggtga ttgttatgtg ggcgaatcaa aatccggtat ttgtttatga aaaagaacct
    56521 tcaagagata ttttatgtat tgactgcaaa tctttttacg cctccgtaga gtgcgttgaa
    56581 aaggatcttg atccccttac aactaaatta gtagtcatgt cctatccgtc cgattcgaca
    56641 gaaacacggg gtagcggatt aatcttggct tccagtcctg cagcaaaaaa agcttacggc
    56701 atcaccaata tcagccgtgc cagagatctt cccttcccct atccaagtga tttatatatt
    56761 gttgccccaa ggatggccta ttatatggaa aagaacagag aaatcaattc tatctataaa
    56821 aaatatgcag acgaagcgaa ccatcatgtc tattccgtcg atgaaagctt ccttgatgta
    56881 acaaatagca tggcactctt tggtaaaaca aatgcgtacg acatggctaa actgatccat
    56941 aaagatgtgt ttgagcagac cggaatctac acgactatag gaattggcga taacccgcta
    57001 cttgctaaac tagccttaga caatggctca aaagacggaa agcaaatgtt tgctgaatgg
    57061 cgttatgaag atgtaccaga aaagttatgg aaaatctcag atatcactga cttttgggga
    57121 atcggcaaac gaacagcaaa acgtctgaaa caaatgggta tacattctgt ttatgattta
    57181 gctcacgcgg attattatca cttgaaaagc aagctagggg tcatcggtac tcagctttat
    57241 gcccatgctt ggggcatcga tcgaagtttt ttgggacaag aatatacacc aaaatcaaaa
    57301 agtatcggaa atagtcaaat cctagataga gattatacaa gacgagaaga aatcgagatc
    57361 gttatcaaag aaatggccga ccaagtcggc actcgcttga gacgatctgc agcaaaaaca
    57421 caagtagtca gcttatgggt aggatactct ttaggctatc ttgatccaaa tggcaagacc
    57481 gggtttcacc agcaaatgaa aatcgaagcg acaaatgcta gcagagatct agcagatgct
    57541 ttattgacca ttttccacca gcattaccac taccaggata ttcggcgtgt aggcgtgaac
    57601 tgttccgacc tcgtatacgc gacaggttta cagcttaacc tttttgaaga tcctgaaaag
    57661 cagataaatg aagcgaaagt tgattttgtt gtcgatacga ttagaaaaaa atacggcttt
    57721 caatcaatca tccatgcgca tagtctcttg caaggaggac gcgccatcgc acgtagttct
    57781 ctcgttggcg ggcatgcagg tggtatgagt ggattagaag gtggaaaaga tgagacggac
    57841 agcaaaaaaa ttcattgact ataacgagta tcgagatcgg ccatttggat taaaatgggg
    57901 gactgctttt gcgatggaag aactagtcaa cggtatcaaa aaaaatgaag aagaagcacg
    57961 caaacagcct cttcctaaac aacaaatgac attgcaagaa atcgatagta tactgacaga
    58021 agccttttta tctcgtaaag cagtaatcat tcagctcaat ttaaaagatg aatttggaag
    58081 actcttggat gaggtcgaag ggcacttcat tggtgaagcc tatgaagatt actttatgat
    58141 tgaccatcag ccgatattgt gggaagacgt acggtatatt gagttaaagg aaacaaaaaa
    58201 atggtttgtg acatgagagg ttgtgacaga agtgatcaac ttcaaaaaat aagaaaggat
    58261 ttttcgaaaa ttgcttctta aatttttgtg gaattttggc ttatttttcg aagaagcaac
    58321 ttctggaaca acgtatatta gatatcagag gttgtgaaaa agtcgcttag ttttgagtaa
    58381 caagccaagg cgctgatttc acaacctctg tctatctatc catctattcg gtaagattca
    58441 tgcatgacgt cttctttatt tagtatgtag agcccttttt cttctgacca ttcaacataa
    58501 atcagctgtt ttacatctgc atagccttct ttcttcaagt tctccataag ccatgcttca
    58561 gtcaattgat tggactgaag cactttatgc tgaatttgcc cttcatctac aagcaggatc
    58621 gataaagctt tgtcttcatc tgattttttc aatacactca tttgaccggc attctctagg
    58681 ataacatgtt tggcattttc aagaaaaaag cattcttgct gtcttaagat tgctcgcaac
    58741 tgctccatct cgatatggtt atttgtcaac tctgtcatgt tgatgacgcc gtctttgatt
    58801 agaacagatg gctcgccttt gacccaacga ttgacctttt catttttttg gacgatacgt
    58861 tcgataccat aaatcattac tgcccaaagc gcaatggcaa ataggacatg ccctacatgg
    58921 acattgtcat cataggttga ttcttctaag atcccaccta aaacaagcgt atagactaaa
    58981 tcaaacggtg tgatttctga catggatttc ttcccaagca aacgtaccac taataataaa
    59041 ccgatcaacc cgaacaccag tttcattgta attgaaaaaa tcattttttc tccccctaac
    59101 tatctgttaa ttaaattata tatgctttct cacgaacacg catggaatat acaaggaaga
    59161 aatgtatcct tttactaaaa aaaggactgt gacactgtag tgacccccaa aagttagact
    59221 tttttggagt ggagaaatcc actccttttt tttatgctct aaaatgatat ttttacacaa
    59281 ccgttacggt tgttttacga aattggacga gactttgcca gtttaatttc tgttttatcc
    59341 gttcattatt gtagtaatag atatagctat cgatggctga ttttaattcc tcgaaacagt
    59401 tataaacttt cccgtgaaaa atctcttgtt ttaataagcc aaaaaaattc tccataagtg
    59461 aattatctaa gcagttccct ttccgagaca tgctttgaaa gattttgtac tccttcaatt
    59521 tgtttctata agctttcatt tgatacgccc aaccttgatc tgagtgaaac gtacgacgat
    59581 agggacaatc gttagtggtc tggatagctt cctccaaacc ttccattacc gctaatgcat
    59641 tgggcttttc agagatacga taggataaaa tctcactatt gaacatatcc ataaaaggat
    59701 ctagatacaa tttcttttga cggataatgc ctttggcatc cacttcatgg tatttaaatt
    59761 cagttgtatc cgtcgtgatt ttctgatggc agatactggt gtagaaacga cgatggatcc
    59821 gatttttggc tactgctcca acttttcctc gataagaatt gtagcgacgt gatttacgcg
    59881 tgtatgccgt tacttttatt cctagcttct tgatcaagcg ctgaactttc tttttattga
    59941 tagagaaacc gcggtttctt agttcattgg tcatccgtaa acagccataa tccttgtgct
    60001 tctcccgaat tttaagcatt tccgcttcaa tctcttgatc tggattttta cggtccaatc
    60061 gcctttgcca tccaaataat catgaacgat ctttaattta agttcaaaag tatatttaac
    60121 cataaaaaat accgacctcc aaaagttaga ttttttggtc taacttttgg gggtcggtac
    60181 acaaatcgtg tcacagtccc ttttttgaaa ataaacggtg ttcaaaagct tgcatctgcg
    60241 gtaataagtc cagccaagtt aaaaacataa gaagctgttt ttacttggct gttcttatta
    60301 cttgatgcaa ggcagctttt tcacaacctc ttttcaaata tttcgttttc ttattctaca
    60361 aatggttctt ctcctaacgc ttgttgagcg gctagattca acatgctcca ttgtcggtca
    60421 aagcctggct ggaagaagaa gtcagcttct gctagttctt ctaaagtcag tttgttttgg
    60481 atcgctagtg ccaatacatt tccttgacct gtaacatcat aggtagataa tactgctcct
    60541 cctagcaatt gatgggtcat tggatccgag aataattgga tggacacttt tggatttcct
    60601 tgttcttctg gtacatattt tggtcgtaac gtatcttcat aataagacac tcgtacatct
    60661 actcctgctt ttgctgctgt aaagctattc aatccgcttg ctgcaaaatg atagtcaaag
    60721 acacttaatg cagaggaacc tacgactccg ccgaacggtt tgtttggtac ttcttcaaaa
    60781 agatgtttta ctacataacg tgcttctcta cgtgcaacag tcgctaaagc gatcggcatt
    60841 tttttgcgtg ctgggataga ataagcaagt gtagcatctc ctactgcata cacatctgga
    60901 agattcgttt gcaagtattc atttgtttgg atccagccac gttcatctaa gtcgacgatc
    60961 ccttttaacc attctgtatt tgccttcaca ccggcagctt gaatgactag atctgctggg
    61021 atttcttttt cacttgtttt gattgcctca acttttccgt taccagtaaa agcttcgatt
    61081 tttgcatttg tcaaaacttc aataccgttt tcatttaggt gttgttctaa aatatctgtc
    61141 atctcagcat ctaaataagt gcctaaaggt ctatcgatca catcaagcaa tacgacttct
    61201 ttcccagctt ttcggcttgc ttctgctgct tcgatcccaa tgtaacccgc acctacgaca
    61261 gcgatttttt taatagccgg atcatttaat ttttctttga ttttggttgc ccaattgtat
    61321 ccacgcatca agtagacatt ttctagatct gctcctggta ctggcagatt gtttggtttg
    61381 acaccagaac tcaaaatcaa tttgtcataa ggatattctt ttgtttcgtt atctgatgcg
    61441 ctagtaaccg ttactgtttt tttatcggca tcgatcgttt ttacttcgtg attatttaaa
    61501 atatgaacat tggattgcgg aaagttttct ggtctgaaat tacgtacatc atttacatct
    61561 gttaccttgt cttctaaata cagctccata ccacatgaca tgaaggaaat atagtctcct
    61621 gcttcaaata gcgtgatatc tacattttca ccgtatcgtg tcaatagttc caagatcgat
    61681 tgatgccctc catgagatgc acctacaatg acaactttga ttttttccat tgatgaaacc
    61741 tccttgaata ttcttttaaa atcattctaa acaatttaaa cttaacatta cattagttat
    61801 gaatcaaaag aaacgcgttc atttgaacta aatttaaaaa acaatcgtct ccttgcagaa
    61861 tataccgcaa aattaacgat tgtttttttg ataaaatcta tgaatcactg ttctgttaaa
    61921 aagtctttga tccgtttgca ggcctcatgt aatttttcca tgctgctagc ataagaaatc
    61981 cggatataac cttctccttc tgggccaaat gcaattcctg ggatacacgc aacttttgcc
    62041 tgttccgcta attctacaca aaactgccaa gagtcagttt gaatggcagc tgggagtttg
    62101 caaaacaagt aaaatgcacc gtttggctgg gtcacttcaa atcctaaagg cgccaattgc
    62161 tggaccagat agtctcttcg tgtttgatat tgctctttca tattctcgct atctttcacc
    62221 ccatttatta gcgcttcagc cgcagctttt tgcgacatcg ttgtagcggc agtcaccaga
    62281 tattgatgga ctttaattag ttcgtcaata agggcttttt gagcaaaaat aaagcccact
    62341 cgccaaccag tcatcgcatg tgacttggat aacccgctta tcacgattgt ttgttctgga
    62401 agataagtag ctatggacat atgcgttcca ctataagtca attcagcata tacttcatca
    62461 cttataacaa ataccggata tttttttaaa acctcagcga ttgctttcaa ttgttttgca
    62521 gacaatgtcg tcccagtagg attgttagga tagtttaaaa tgactgcttt gacagctgat
    62581 ccatattgtt caaatgctcg ttcaaattgt tccggctgac agacaaaccc tgtgtcagaa
    62641 gtatctatcg ggatcaattc agcaccagct agttccacta atggctgata tcctgaataa
    62701 gcaggcgctg gaataagaac cttgtctcct tcttccaaaa cagataacaa cgcagaggca
    62761 atcgcttccg ttgcaccaac tgtcgtcaaa acttccgttt gcggatcata agttaatcca
    62821 taacgctgtt gctgaaatat acaagccgct tcccgcagtt cctctaatcc tctcattccg
    62881 gtatagtgag aaaagtcttc ttcaatcgct gctattcctg cttgcttgac atgttcagga
    62941 gttggaaaat ccggttctcc cagggtgagt ttgatcacat ctggtatcga cgatatttgc
    63001 tgatcgaatt gtcgtatttt tgatacttct attctagaaa gcctaggact aaatcgattg
    63061 gataaattca tcattattta ctcgctcctc ttttgaactg ctatcgattt ttacaagaag
    63121 attttctgta aaaagaatcg ttttgtacca ttctacacca ttttctaaaa catccatatc
    63181 aaaatcgaac gtcggatcat gtaaagcagg ggtatcaccg acacctaaaa agaaaaatac
    63241 acatggatat tgttgcgtat atatgccaaa atcttcggct tgaagaactg gagcatctaa
    63301 ttcatgtagt ttgtttgaat ctaacagtgc tgcatataag cctctatggt tgattacagc
    63361 tggatagccg tcattatagc gaaaagaaat agtagctgta gagtgaaact gttctgctaa
    63421 atggtctaat cccctcttca aataattttg catatctgaa ctgtaagaac ggatacttcc
    63481 ggatacaata acttctccag ctaaaacatt tcggatcgtt ccaccttgga tttggccaaa
    63541 tttcattaga tgattccact ctgccggtaa ttgccggtca aaatcataaa cattcttcaa
    63601 aaatcgtaca gctgcctcca gactatcgat tcctttttca ctagaagcaa tatgtgcaga
    63661 ctggccttta atgataatgt ctgtttcact gctttgtgcc atcaaaggtc ctggtcgaga
    63721 gaaaacttct cccttagcta gtccaggcca tagatgaaag ccaaatattg cttgtacttc
    63781 atatttatcc aacaatcctg actgaataac gctttgtgcg ccaccggaaa tttcttctga
    63841 tggctgatag atcagtacta cattataaat aagatcctca atgtgtttag ttataaagtc
    63901 agtcaaccct aaaagcatcg ccatatgtcc gtcatgacca catgcatgca tataaccttc
    63961 atgcttagaa gcaaaagaga gattcgtttc ttctttgact ggcagtgcat cgatatctgt
    64021 tcgaaaagca atcgtttctt cttgctgatt atcaaaataa aggagtagtc ctgtttcgcc
    64081 gatttcatgg ataacggcct cgctgttttt tacttgttca tataaatatt tttttgtctt
    64141 gaattcatga aacccgattt caggaatttg atggagtgcc attcgatatt ctttcagcat
    64201 ccgtattcac catcccttca tagataccct tcactactgt ttcatattga ttattcggta
    64261 caccgatgat cagattcaac tcctgtgctc cttgtgataa gatcgatgtg cgaatttcta
    64321 atttgttcaa tatcgataac actttcccag ataatccaat caattcttta tgcggacccc
    64381 caacgacaga gatcaaagct aagtcttcga tcacgacgat ttcttccacg ccaagtgttt
    64441 cttttaattc tttcgtgatg agaaataact tatcggcaat cgcttctgct gagacgatca
    64501 ctccgatatt gtcgatccct gaaggaatat gttcgattga tatctcatgt ttagcaaaaa
    64561 tgctcattgc tttccagata aacccgattt catcggacat atgacgtttg aataaagtga
    64621 tggaaagaaa atccttgcgt ccagctattc ctgtcagtcc attttccttt tctatttcgt
    64681 gattcgatat ttttgtccct tgagcgaaag gatcattggt attttttatt tggatgggga
    64741 tatcagcctc ttgaactggg aaaacagctg cttcatgaag aacgttagcc cccatataag
    64801 ccatctctct cagttctcta aaagagattt cctcgatgat tttaggatga tcgatgattc
    64861 gcggatcagc catcatgatt cctgaaacat ccgtccaatt ctcataactt tccgcttgca
    64921 acatcttcgc cagtatcgcg ccggtaatgt cgcttccccc acggcccaat aatttttctt
    64981 ttcctgcagg gttcgccccg taaaaccctg gaacaaccat tttcggatat cttttaaatg
    65041 cttttgtgat ttcctgtgct gttttttcct gatcgatttt cccatcatag tcaaagaaaa
    65101 tcaggtcttt tgcgtcaata aactggtaac caagatactc agccatcagt tgagcagtca
    65161 gatattcacc tctacttact aaataatctt cagttatctt ttcgtcttcc agttgtttct
    65221 gtatgcgtgc tagttcatct tcaataggta actgcagggc aagaacatct cttacttgaa
    65281 tgaaacgatc acaaatcctt ttccaaaggg gtgtccaatc aacatgatgc tgaaggtaag
    65341 cataaatcaa ataaagtaag tctgttactt tgtcatcatc tgacgtacgt ttgcctaaag
    65401 cagaaacaac gatcacttgg cgattgggat ctgaaagaac aattgtacgg acttttttga
    65461 attgctcttc atgagacatc gatgttccgc cgaatttcgc tactttcagc gtattactca
    65521 tcttgccacc tccgctattt tctgcattaa agctgcagca atctgtacgg cattcgcagc
    65581 ggctcctttg cgtatgttat cggcagtcgt atagaacaac aatccgttct ctaaagaagt
    65641 gtcttttctg atcctcccaa cataaaccat atctgttcct ctagcaagaa tgctcgtcgg
    65701 atatttatgt gctgctagat catcttctaa ttgaatccct ggaaactggc tgagacactc
    65761 tctaatttct tccgtcgtaa actctttttg cagttgaact gccacagaga ctccatgtcc
    65821 attttcgatt ggcacacgta cgcaggttgc tgatactggc aaagcaggct gatgcagaat
    65881 cttacgggtc tcatttatca ttttctgttc ttcttttgta tacccatttt ccaaaggctg
    65941 atcgatttcc ggaatcaccg tttggctaat attataagga tacaaaactg gttcctcgtc
    66001 attttgcgta cgatgaagat cttcaatgcc tttttgcccg gaaccagaaa ctgcttgata
    66061 ggtcgaataa ttgactcgct ggataccaaa ggcttcttgt aaagctttaa gcggaagtac
    66121 cgcttgaatg gttgaacaat ttggatttgc aatcagccga ttcaatgtat agtcttccag
    66181 attgacctct ggaacgatta atggaatatc cgaatcttcc cgccatgctg aggaattatc
    66241 tatgacaaat agtccctgac ttcgtgcgat tggcgcaaac tctttggata cagaagcacc
    66301 tgcagaaaat agcgctaaat catatccttc aaatgaagtt tctgtcaatt cctgtacagt
    66361 gtgtttcttt ttcttgaata cacaaacttt accggctgaa cgttttgaag ctaataattt
    66421 caatcgtcct actggaaaat catattcttc taacactttg agcatcgttt ggccgactaa
    66481 tccggttgcc cccacaatac aggtatctat ttcgcgcatt tttctccatc tcctctataa
    66541 ttcgcgtaac gcagcaatca atgctgtatt ttcttttgtc tgatcatcac ttatttttaa
    66601 tacacgtgca ggtattccac cgacaacagt ttctgctgcc acatcttcta aaaccactgc
    66661 tcctgctgcc acgactgcat cttttccgat atggacacct tcaacaatca ctgcattcgc
    66721 acctaccagt acgccgtctt ctacgataac cggtttggcc gatgctggtt cgatcacacc
    66781 tgctaagaca gctcctgcac caatatggca gtttttgccc actgtcgctc gtccacctaa
    66841 gacagcaccc atatcaatca tcgtgttttc accgattact gcaccaatat tgataatcgc
    66901 tcccatcatg atcacggcat tgttgccgat tgacacttga tctctgataa tagcacctgg
    66961 ttcgatacga gcattaattt ttttaatatc tagcaaagga actgcgctgt atcttgcagc
    67021 agtttcgatt tcgatttcaa tgattttttc tgattcagct tctaaaaccg gagcaatcgt
    67081 ctcatagtca ccaaaaacaa cgaagctgct tccttcacca aaaactttac tttctttaaa
    67141 ttcgattggc tcggttacat tcagatagac tttcacaggc gtctttttag atgccgtttg
    67201 aatgtagcgg atgatttctt gagcttccac gttttttaca cccctttgtc cattaataaa
    67261 tcttctaatt tgtaataacc tggtgactga tctttcaacc agtccgctgc ttctactgcg
    67321 cctgcagcaa agattcgatt agaaaaagat tcatgtttga tcgtaaatat ttcatcagta
    67381 gcagcaaaca atacatcatg ttcaccaggt aaagaacctg cacgaatact gtgtacacca
    67441 atttggtttt cttctctttt tttcccttgc cagttgtata cgggctgcag cttttgcact
    67501 tcttggattg tttgaagcag catatttgca gtaccagatg gtgcatcttt tttacgacta
    67561 tgatgttttt caatcagttc gatctgccag ccttgcaaca ttgcagctgc ttgcttgatt
    67621 agttgattca tcaccatgat gccgaacgaa aaattagcac tatacatcac aggtacatgt
    67681 ttggcatgtt cttttatttc ttggaactgt gattgtgtat aacctgtcgt gccaatgact
    67741 aacggaagtt gatatgataa gctatacgaa aggattttct ctaaattatc tggatgagaa
    67801 aaatcaataa gcagttctgg cagttccgta aaagcaagcg tagttgcttc tttaggtgcc
    67861 gtccgtaaaa gaaggaccgt atctcctctt tcttgtgcaa cttcttcgac tctatttccc
    67921 atctgtccac tgccaatcag tccgattttc atttttcaac cgtcctttct tttaacaaaa
    67981 gctgagctaa ttgtttcttt ttctcttttg aaagagaaac taaaggcagg cgtagaggtc
    68041 cggaaggtaa gtctaataat gacatggctg ctttgacagg aataggattg gtctcactga
    68101 acaaggcatg gatcagttca agtgcattta attgcttttc ttttgcttgc tgccatcttc
    68161 cgtcctgcgt atcttttact aattcatgga ctattttagg ttggatattc gcccatacac
    68221 ttattacacc gcttcctcct acactcatta ctggtaggat caaatcatca tttccactgt
    68281 aaaggaagaa ttcttctcca atcaaccgag cggcatccat cacataagcc atatctcctg
    68341 aggcttcttt caaaccaatg atattaggat gttctgctaa atttactaat acatggattg
    68401 gaatcgacat gcctgttcta gaaggaacat tatacaaaat aagcggaatc ggtgaggctt
    68461 ctgcaattgc tgtaaaatga gcagctagtc ctgcatcact tgttttgttg tagtaagggg
    68521 tgatgaccaa aagtgcgtct gcccccaaag aagcaaaatg cttcgctttt tcaatcgttt
    68581 ctttcgtatt attcgttcca gctcctgcaa tcaccggcac acggccagcc actttcttta
    68641 ctgtcagttg aaggatctgc tcctcctcag attgtgtgag cgtagaagat tctcctgttg
    68701 tacctaaaac taataatcca tctgtttgtt catctaaatg gaattggatc aatttttcca
    68761 aaccagcata atctactgat ccctcttcat tcatcggcgt gatcagcgcc acgatcgaac
    68821 cttttatcat cttcattcct ccaatattct tgtccattca tgaactgctg ggccagccat
    68881 ttgtatcgca tcctcaccag agatcatcaa gtctccttgt tccaagtgaa caactacctg
    68941 atctgctgaa attttcccag tttccttagc aaccacataa gaggcacagc aacctgtacc
    69001 gcaagcaagt gtccaaccta ctcctctttc ataggtacgg acgatcaatt cttgttcatt
    69061 gactacttct acaaagttga cattggtttt ttctttgaac aaaggatgat gacagatcag
    69121 ttcacctctt tttctccaga cttcctcacg cgcattttca acaaaaacaa cggtatgaat
    69181 cgttcctaaa aataaactag tgatcgttac tttttcacca ttgatctcta tttcctggtt
    69241 ttttattgga taagtttgat tagctttgat tttttccgga gaatcatctg gcactcccat
    69301 atctacgctg caataaaaag gtgagggatc caacaccgta atttttcttg tgcctgctaa
    69361 tgtctctacg ttgaattcct gttcattcat catgttctga tcatttacgt atcgagcaaa
    69421 acagcgaatg ccatttccgc acatcggcgc gcggctgcca tctttgttgt aatagatcat
    69481 ttccaacgga tcgattttta cggcgatcaa tccgtctata tcatattttt cttttgtgca
    69541 taaagaagcg gctaattgac tataatctgt gtcttctgcg taatctaata agataaaatc
    69601 atttccgcag ccattatatt tatgaaggat cataggaaac ttcccccctt agtagatcag
    69661 aaaatgcttg tctgcgaaca atcagtcttg attggccatt attgacaaaa acaactgctg
    69721 gtcgtgtcgc tcgattgtag ttgctgctca tcgagtatcc ataagctccc gtggaataaa
    69781 cagctaaaag atcacccgat tctgctttcg gcaaataagc ttctttaatt accacatcgc
    69841 ctgattcaca catttttcct gcaatcgtca ctttctctgt tttttcttcc gacagttttg
    69901 ctgctaaatc acaatcgtat tctgcctgat acagagctgg acggatatta tctgtcatcc
    69961 cgccatctac aaagtaatat tttttatgtg gtgtcttttt gatgaaacca atcgtgtata
    70021 gtgttgtacc agcttctcca acaatacttc tacccggttc gatcagtaat tgacgaatgg
    70081 tcagttttcg tttttccaaa gcttcttccg tatattcaat cagttttttt agtgcctctt
    70141 cgactgggat cggctgatca ttttgtgtat aacgaatccc aaaccctccg ccaagattca
    70201 aggaaagagg ttggtcaaaa tcggttaagt aattcgtcaa tttgtcgatt tcagctaacc
    70261 aagcagtaac atcaaaaatt tgtgacccga tatgagcatg aaatccttct aactctagat
    70321 agctgctttc ttttatcaac tgaagggctt gttggcactc tttactttca tagctcatgc
    70381 cgaattttga atcaatatgc gcagtgacga tatattcatg agtatgtgct tctactccga
    70441 cattcaaccg aagcatgata caaatttttt ttaaatagcg ttggcttaat tctgctaata
    70501 attcaacttc catcaaatta tcggcaacaa tatgcaacaa atcattttca agtgcataga
    70561 tcagttcctc tggcgtcttg ttgttaccat ggaagtagat agtatctcta ggaaaatcag
    70621 cttgcaaagc ggtatagatt tccccaccac tgacaacatc tagcccgaat ccatattcac
    70681 gaactaaatg cagcatctca atcgtttgga atgctttaga ggcgtaaagc acttttgtat
    70741 caaaacgttt cgatacaaag cctcgcttga atgacagcat cgtttgtctc atcttttctt
    70801 catcatacac atacagaggt gtcttatact tttctgccaa tgtgcttgct gtgactccgc
    70861 caattatcaa ttctgtcatt ttttcattcc tcttttcact ttttttccgt ttttattgga
    70921 atttcatttg ataaagattt gaattttatt ggaataatat taaacaaaat tttctgaatt
    70981 gtctagtata tttcgaaata tttttttaaa aataagaata aaaatggtta taaaaacaaa
    71041 atacccgaac tattagaagc tatttataca taaaaacata aattcaacac tatttagtga
    71101 tgaaaaaata ttttcgcttc aatatagttc ggaatagttc ggatattttc aattttatga
    71161 atcatttcaa tttcttcata aataagtgca gttttttctt tctctagctt ttgccattca
    71221 tctttcaaaa tataaataaa atcaaatact tttttatttt tcaatttgct gattccacaa
    71281 aaaacctctt gaaaggcaga tccgatgatc tgcctttcaa gaggtcaagc tctgttttca
    71341 aattcttatc aatccgttag cgaattattt tgacgcacgt tttacataag aaccttctgc
    71401 tgtattgatt tccaacaatt catctgtttc gatgaagtca ggaacattga ctactaagcc
    71461 agtttccatt gtcgctggct tacctgaacc agtgactgtt gcacctttga tggaaggttg
    71521 tgtttccaca acacgtaata cgacagttgt tggtaattga acgccgatga cttcgctacc
    71581 gaaaaattgg atttttactt ccatgttttc taggatatat ttcatttctt cttctactgt
    71641 ttctacagga atttcatatt gctcatatgt ttccaaatcc atgaagaaag ctgtatcatc
    71701 catcgtgtac aaatattgta caggttttgt gtcgatatgt gctttttcaa atttttcttc
    71761 tggtctgaac gttgtgtcgt atgttgcacc tgaacggaca tctttcagtt tcatacgcat
    71821 aactgtattt cctttaccag gtttatggtg gcttgcatcc agaactttaa tcagtttgcc
    71881 gtcttgtacg aaagtcatac cggctcttaa atcacttgct gagatcatta tttttgctcc
    71941 ttcttttctt tatcataatc aactttattg tatcagacaa ccggccagaa aactagagta
    72001 ttctctatct tttaaggtct catgcctatt tgtcagaaaa ataaacacgg gtaaacgatg
    72061 ctatcgaaat atttttttct ttcaagcctt tgacttttat tttttttcat gctatcgtta
    72121 ataaaaattt tacttggagg gatacacatg acagtcagca accaaaaaca attgaatcgt
    72181 tgctgttgta tggtgcataa aagcagcata ctatttgtca tgtctattaa ttgcccttca
    72241 tagaatgagt accaggtaac ttatcttttt atctactcaa tttttctcta tgtctttcaa
    72301 ggagctgatt taatagtcag ctcctttttt tattatcttt ttttaggagg cccacatgat
    72361 tatctcgaca attacagaag ctattggttc cacaccgctt tatcgctttg acaatcagca
    72421 ctattctatg cctaaaggtt ctgctattta tgcaaaacta gaatatttaa atcctggagg
    72481 aagtatcaaa gatagattgg gcagttattt gatcaaagaa ggatttgccc aaggaaaaat
    72541 caatgaaaaa acgacgatca tcgaaccaac tgccggaaat acaggaattg ggatcgctct
    72601 ggccgcactc acatacaaat taagaacggt ttttgttgtt ccagagaagt ttagcttaga
    72661 aaaacaacaa ttgatgaaag cattgggagc aaagatcatc cattctccta gtgagcaagg
    72721 aatcatcggt gccatcagca aaagtaaaaa acttgcagag gagatatcaa acagctatct
    72781 gcctcttcaa tttgaaaata aagataatcc tgctgcttac tatcatacgt tagggccaga
    72841 aatctttcat gaaatcaaag aaaatatcca tagttttgta gcaggaattg ggagtggtgg
    72901 aacctttgct ggaacttcta cctttttgaa agaaaaatat cccgacattc gaataatcgg
    72961 tgtagaacca gagggctctg tgttaaatgg tggtgatcca gcccctcacg aaattgaggg
    73021 tatcggtgta gaattcattc cgccgtttct ttctcccctt tcaatcaatc agatcgagac
    73081 aatctctgat gtagaagggt ttaactatac taggcagtta gcacgagaac aaggactatt
    73141 agttggaagt tcgagtggtg cggcttttgc agcagcatta agagaaattc gtcgtttacc
    73201 acctggtcat cgtgtcgtta cgatttttcc agacgcagca gaccgctatt tatcaaaaaa
    73261 catttactta taggaggaaa gaaacatgca cattcaaaca aaattgatcc acggaggcat
    73321 cagtgaagat cccacaacag gagctgtcag tgtacctatt tatcaaacat ccacttatcg
    73381 gcaagatggc gtcggccagc ctaaacaata tgaatattca agatctggta atcctactcg
    73441 ttttgcattg gaagaactga ttgctgattt ggaaggcggt gttcgaggat tcgctttttc
    73501 ttctggtctt tctgggattc atgccgtttt ttctcttttt caagctggcg atcatatctt
    73561 attaggagat gatgtctatg gaggaacatt ccgtctattt gacaaagttc ttactaaaaa
    73621 tggtctcgag tacacgatca tagatacgag taatcttgat aaaatagaac aatccatcaa
    73681 acccaataca aaagcacttt atcttgaaac acctagcaat ccgcttctaa agattactga
    73741 tttagaaaaa agtgccactc tggctcatca acatggattg atagttattg ctgacaatac
    73801 atttgctact ccttattttc aaagaccttt agatctcggt tctgatatcg ttgtccatag
    73861 cggtaccaaa tatctaggcg gacacagcga tgtagtagct ggtttagtga cttctaacca
    73921 taaagatcta gccgatcaga tcggatttta ccaaaatgct atcggagccg tacttggtcc
    73981 ccaagatagc tggttacttc agcgcggaat caagacacta agtgttcgta tggaggaaca
    74041 tcaaaaaaat gcttttgtgg tagctgattt tctattttct catccagcag tagaaaaggt
    74101 ctactatcca ggattacccg atcatgaact ccatggagtt gctaagcagc agatgagcgg
    74161 ctttagcgga atgatttctt ttactttaaa aaatgaagaa tctgctattc catttgttga
    74221 atcactccaa ctatttactt tagcagaaag tttaggtggc gtagaaagtt tagtggaaat
    74281 tccttctgtc atgactcatg cgtctattcc aaaagaaaaa cgagaagagg ctggcataaa
    74341 ggacggcttg atccgtcttt ctgtaggaat tgagtatggt caggatctca taaacgattt
    74401 agctcaggca tttgacagaa tcaagaacta gaagtcccaa taaacgactt agcagaaaaa
    74461 tctaaaaaat atttcagatt gctacacctt ggaaacgata agtgttagaa tcaagtagaa
    74521 agacgttttt gtaaatttca ctaaataatt ctttagtgaa aagcatcaaa acgaatgaac
    74581 aaacagatag gagtcttaca aatgagaatg aatgtcgaaa gttttaatct tgaccataca
    74641 aaagtcaaag caccttatgt acgtgtagct gatcgaaaaa cgggtgcgca tggcgatgtc
    74701 atcattaaat acgacgtccg ctttaaacaa ccaaataaag aacacatgga catgccaagt
    74761 ctacattcac ttgagcactt gactgccgaa ctaatccgca atcacgcaga ttacatcgta
    74821 gactggtctc caatgggatg ccaaacaggc ttttacttga ctgtattgaa tcatgaaagc
    74881 tacgaagaca ttttagatgt tcttgaagca acaatgaaag atgttcttga agctactgaa
    74941 gtacctgcaa gcaatgaaac acaatgtggc tgggctgcca gccatacact agaaggtgca
    75001 caagctttgg ctcgtgaatt tttagcaaaa cgcgatgaat ggtctgaagt agaagcatag
    75061 tttctaaaag aacgtaaaga tgagaagcaa tatagctatc ttatcttcgt attttattaa
    75121 atatttattg tctgaaaaga gttctaaacg ggaaaacaaa tagctagttt tcagtttagc
    75181 gctcttttta ttatataaaa tagaaaggag aaaactttat gtctatttat aattttgaaa
    75241 ctactttaga agacggcact gtctattcat tgaaaaaata tgcaggcaaa ccgataatca
    75301 ttgttaacac tgcaacaaaa tgcggtctag cacctcaatt taaacaatta gaagaacttt
    75361 accaagctta tcagacacaa ggtctggtta tcttaggctt tccttccaat caatttaaac
    75421 aagagctaga ttcagcgact gaagcagcag aagcttgtaa aaccacttat ggcgttacct
    75481 tccctatgca tcaattgatt gacgtaaatg gagaaaatac agatcctctt tttacttatc
    75541 ttaaaaatga agctcctggt actgtcacta aagcaataaa atggaatttt actaaatttt
    75601 tgattgatag aaatggcaaa gtaatcgaac gatttgcacc acaaacttct ccattgaaaa
    75661 tgaccgctgc aattgaatcc gttctttaac ttaataaaaa taaaaaaaga tgaactattt
    75721 ctagttcatc tttttgcctt tgcgtggcga cgtcctactc tcacaagggg caacccctca
    75781 ctacaatcgg cgctaagaag cttaacttct gtgttcggca tggttacagg tgtatccttc
    75841 tcgctatcgc caccacactg tggtgttatc ttttattgag taaattttgt tcactcaaaa
    75901 ctggatttga agtca
//
LOCUS       DAYNVV010000006        63387 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.006, whole genome shotgun sequence.
ACCESSION   DAYNVV010000006 DAYNVV010000000
VERSION     DAYNVV010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 63387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.006"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            163..2697
                     /gene="secA"
                     /locus_tag="ACGXWR_000548"
     CDS             163..2697
                     /gene="secA"
                     /locus_tag="ACGXWR_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFK0802160.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDIQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGDE
                     DAVIQSKMLTKQVEAAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIVDFAGSTLVHEDSISLTDIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKDAN"
     gene            2824..3925
                     /gene="prfB"
                     /locus_tag="ACGXWR_000549"
     CDS             join(2824..2895,2897..3925)
                     /gene="prfB"
                     /locus_tag="ACGXWR_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HFK0802161.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAVMQEEAEARI
                     NALDEKMNTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            4030..4716
                     /gene="ftsE"
                     /locus_tag="ACGXWR_000550"
     CDS             4030..4716
                     /gene="ftsE"
                     /locus_tag="ACGXWR_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HFK0802162.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            4709..5593
                     /gene="ftsX"
                     /locus_tag="ACGXWR_000551"
     CDS             4709..5593
                     /gene="ftsX"
                     /locus_tag="ACGXWR_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HFK0802163.1"
                     /translation="MIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFMAVI
                     MNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELKKIQ
                     NEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEKAADLKNVSRSDYGGASSDRIF
                     QIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFF
                     LEGGWIGLIGAILPILIITFGYAWFYQLINPSLLRSHYSLIHPENIVWKINLLMVGIG
                     VIIGSLGSIISMRRFLKF"
     gene            5745..7193
                     /gene="cls"
                     /locus_tag="ACGXWR_000552"
     CDS             5745..7193
                     /gene="cls"
                     /locus_tag="ACGXWR_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFK0802164.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDTLGE
                     EVREALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPEFFPTIHSTGDMAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEVYENRGMMIKMKEGLARLISPLL"
     gene            7530..8387
                     /locus_tag="ACGXWR_000553"
     CDS             7530..8387
                     /locus_tag="ACGXWR_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HFK0802165.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQAENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            8502..9422
                     /gene="pstC"
                     /locus_tag="ACGXWR_000554"
     CDS             8502..9422
                     /gene="pstC"
                     /locus_tag="ACGXWR_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HFK0802166.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            9422..10306
                     /gene="pstA"
                     /locus_tag="ACGXWR_000555"
     CDS             9422..10306
                     /gene="pstA"
                     /locus_tag="ACGXWR_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HFK0802167.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            10321..11127
                     /gene="pstB"
                     /locus_tag="ACGXWR_000556"
     CDS             10321..11127
                     /gene="pstB"
                     /locus_tag="ACGXWR_000556"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFK0802168.1"
                     /translation="MKKYNWNETNVITMPKDKEVALYTNDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYKDVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            11143..11901
                     /gene="pstB"
                     /locus_tag="ACGXWR_000557"
     CDS             11143..11901
                     /gene="pstB"
                     /locus_tag="ACGXWR_000557"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFK0802169.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWEDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            11914..12591
                     /gene="phoU"
                     /locus_tag="ACGXWR_000558"
     CDS             11914..12591
                     /gene="phoU"
                     /locus_tag="ACGXWR_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HFK0802170.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            13155..13847
                     /locus_tag="ACGXWR_000559"
     CDS             13155..13847
                     /locus_tag="ACGXWR_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFK0802171.1"
                     /translation="MLLIGGKQGVFALGSLIINIVLLLLLLLLFTKTEGISLLNIAIL
                     FVVIGIIVSILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYL
                     TRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKQQPKISAKQLWLSGRQVGRDVI
                     GSMANILLFVYISGAIPSLLLYLGNQWSFKETVERHLSLELLRVIAGSLGIVLSIPIA
                     VLFFLAVRRLKK"
     gene            13844..14611
                     /locus_tag="ACGXWR_000560"
     CDS             13844..14611
                     /locus_tag="ACGXWR_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFK0802172.1"
                     /translation="MNVLIILVGIFAISVLFVGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILVLSIIGFLLIAVVILFFINGYNLKMRAAFASILIFLFCFLLLIPITDFLAI
                     QGFTSIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     MSFNQLRHASFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDISFQQIINEKSFVL
                     EYTMAILTTLAALLVLPLTCVTTAYLFTKKKEHLKME"
     gene            14711..16279
                     /gene="liaX"
                     /locus_tag="ACGXWR_000561"
     CDS             14711..16279
                     /gene="liaX"
                     /locus_tag="ACGXWR_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HFK0802173.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDELENSEEKISEPVDPKEKERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEATGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSDDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVNQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATPENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDSIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDDEIAQVQL
                     STTTGSIYLKDTDK"
     gene            16455..16763
                     /locus_tag="ACGXWR_000562"
     CDS             16455..16763
                     /locus_tag="ACGXWR_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0080135 - regulation of cellular response
                     to stress [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HFK0802174.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTKKRKEAEKIDDDEWSDF
                     "
     gene            16763..17113
                     /locus_tag="ACGXWR_000563"
     CDS             16763..17113
                     /locus_tag="ACGXWR_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFK0802175.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALFVAILM
                     SLVNVIVSEHNSRK"
     gene            17279..18217
                     /gene="hprK"
                     /locus_tag="ACGXWR_000564"
     CDS             17279..18217
                     /gene="hprK"
                     /locus_tag="ACGXWR_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HFK0802176.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            18232..19062
                     /gene="lgt"
                     /locus_tag="ACGXWR_000565"
     CDS             18232..19062
                     /gene="lgt"
                     /locus_tag="ACGXWR_000565"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFK0802177.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLVLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGSLPDYDRSLGKNQQII
                     "
     gene            19106..20131
                     /locus_tag="ACGXWR_000566"
     CDS             19106..20131
                     /locus_tag="ACGXWR_000566"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFK0802178.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHHLPDSIRAFTDMEDAVKDADAVLFVIPTKAIRSVAKELVAKLNTKPVI
                     IHASKGLEQGTHKRISEILLEEIPTEKRKAVAVLSGPSHAEEVAKHDITTITAASTNV
                     KAAKYVQELFMNHYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            20146..21084
                     /gene="galU"
                     /locus_tag="ACGXWR_000567"
     CDS             20146..21084
                     /gene="galU"
                     /locus_tag="ACGXWR_000567"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFK0802179.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYIMSLGKTLEAEGSKINHNPKGITEIKEEKKK"
     gene            21209..21658
                     /locus_tag="ACGXWR_000568"
     CDS             21209..21658
                     /locus_tag="ACGXWR_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HFK0802180.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTQDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIVTKVGGIGKTTAKATVAGKVGGTAMKFLKTKNILKRQEENKNG"
     gene            21651..22253
                     /locus_tag="ACGXWR_000569"
     CDS             21651..22253
                     /locus_tag="ACGXWR_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFK0802181.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSSELTGIAKEKAQDLSQQAGDLAGNVKQKVSESAEEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDLKKPADELGSIAKDTSEDIMIDVKDAADKAGETVNEG
                     MSEAKPVADDTKEMLKMAKEDAKEAKKEMKDTMTDSTTNH"
     gene            complement(22316..23419)
                     /locus_tag="ACGXWR_000570"
     CDS             complement(22316..23419)
                     /locus_tag="ACGXWR_000570"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HFK0802182.1"
                     /translation="MNNVKINELRQWMAQHQLELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVDRFDAISDILTGTDSYTDLTSIIQRLQLIKTVEEKDKLIEAGKWADVAF
                     EIGFKTVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGSTKVSP
                     NELVLFDLGVIWNGYCSDATRTVAYQKPTEFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLE"
     gene            23629..24630
                     /gene="ccpA"
                     /locus_tag="ACGXWR_000571"
     CDS             23629..24630
                     /gene="ccpA"
                     /locus_tag="ACGXWR_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HFK0802183.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            24984..25379
                     /locus_tag="ACGXWR_000572"
     CDS             24984..25379
                     /locus_tag="ACGXWR_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802184.1"
                     /translation="MPKKRRKTIVIILTILTIGIGGKFYMDKREAQKQQDLLAVEKQS
                     VKVLKNTFADIKEVKIEQFEKNDMTGIYEALITMTNTEGKAVYFDYSFTKESNEIDGY
                     GVENEEVQKEGITVDEIIVIYTDGSEEKV"
     gene            25376..26632
                     /locus_tag="ACGXWR_000573"
     CDS             25376..26632
                     /locus_tag="ACGXWR_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HFK0802185.1"
                     /translation="MTITDKQYKGISNKVYWLDPKHPQYSKSYKEGAIKNFGETKFQI
                     LKIKNSFDGMQAMAVAPIKNGKVDISQVVIAFAGTNLSDWKDLETDARSVMNLYGNRP
                     GASFSEKATTNKILSVSGLKTAGQINSAIAFANEVKKEYGEAAISTTGHSLGGFLALY
                     VAAEKQWKNVGFNGPDPYDLLSPEAKKWVEENPGMLTNYRNHADFIGNFGGNGTGAEV
                     RISMETAYLNLLASHSLTSWKFDENGKLIIPENENNVKARKQQKENQATQLFSYQLQE
                     LNNIRKKLRLSGGRLTVNEQIYLDDTQARLVVEKLSVKMKSAMEEVIRINQRGIFELE
                     KKWQEGLRQARVVAPSLTEQEIIEALASVGATKENLVDSAKEVYLLRINKARRMGEAF
                     DTLAKEIQDKINEIVARDRELAQQFN"
     gene            26644..26967
                     /locus_tag="ACGXWR_000574"
     CDS             26644..26967
                     /locus_tag="ACGXWR_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802186.1"
                     /translation="MKLEELERDYRSERRQLEAQEDELIHFKNQGLRLMEQEEQRLHH
                     VLKNLALDNEPLFQARRSYSNYQEHYQQALQVERRKLYQQQDELERSYRQKIRQITME
                     KSSYE"
     gene            26960..27226
                     /locus_tag="ACGXWR_000575"
     CDS             26960..27226
                     /locus_tag="ACGXWR_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802187.1"
                     /translation="MNEFLMQLLKELEKNLHRSNVRSVGMGISQQTWAEKRLTDQNHQ
                     MTAEEATQEFSNRHAHLKESVKGQFAEKLTELFQRQEKKLKQFR"
     gene            complement(27389..29734)
                     /locus_tag="ACGXWR_000576"
     CDS             complement(27389..29734)
                     /locus_tag="ACGXWR_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HFK0802188.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLLFAA
                     LGIGIGAGYFAYLVEDTQLPTKKELQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIVLSAQVEKHFSKDEIITTYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSEAYYQKAQQTIQNKGYTIHSTIDKDIYAALQTGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLVGSES
                     RVSDYATTWQEGKNAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINEKITTPFKDVISSLNGNLGNA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSQARIRSANYLANLINQAY
                     QANPEIFGTDEKFDLSSDVMKKKVSGFTGQTAGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANPETKESDDKDD"
     gene            30013..30915
                     /locus_tag="ACGXWR_000577"
     CDS             30013..30915
                     /locus_tag="ACGXWR_000577"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HFK0802189.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAFMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGAEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKVIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     ISMFKAQAFDPEVFPELLAEEVTL"
     gene            31126..32901
                     /locus_tag="ACGXWR_000578"
     CDS             31126..32901
                     /locus_tag="ACGXWR_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HFK0802190.1"
                     /translation="MLNILNPLIDQLKKKHTYFILGIAVLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIHYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     ILASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPTVEIIIA
                     CLLAIYYRKYNSSKKLLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYGIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFDFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVIGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIAVTSMLVFSKLNLKKALSSK"
     gene            complement(33210..34796)
                     /locus_tag="ACGXWR_000579"
     CDS             complement(33210..34796)
                     /locus_tag="ACGXWR_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HFK0802191.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            35047..35271
                     /locus_tag="ACGXWR_000580"
     CDS             35047..35271
                     /locus_tag="ACGXWR_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HFK0802192.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            35413..37164
                     /locus_tag="ACGXWR_000581"
     CDS             35413..37164
                     /locus_tag="ACGXWR_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HFK0802193.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQQLEAKIEGGEA"
     gene            37164..38948
                     /locus_tag="ACGXWR_000582"
     CDS             37164..38948
                     /locus_tag="ACGXWR_000582"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802194.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGVYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFVAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            39283..40134
                     /gene="licT"
                     /locus_tag="ACGXWR_000583"
     CDS             39283..40134
                     /gene="licT"
                     /locus_tag="ACGXWR_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFK0802195.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQNNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            40231..42117
                     /locus_tag="ACGXWR_000584"
     CDS             40231..42117
                     /locus_tag="ACGXWR_000584"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFK0802196.1"
                     /translation="MGKYQELARKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTAFLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLKAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYMDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(42158..43060)
                     /locus_tag="ACGXWR_000585"
     CDS             complement(42158..43060)
                     /locus_tag="ACGXWR_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFK0802197.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            43290..44693
                     /locus_tag="ACGXWR_000586"
     CDS             43290..44693
                     /locus_tag="ACGXWR_000586"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFK0802198.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMATMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     DLIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            44693..46126
                     /locus_tag="ACGXWR_000587"
     CDS             44693..46126
                     /locus_tag="ACGXWR_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFK0802199.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFPV
                     ITGKKKMFEFDKDHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     NEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDTVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            46271..47197
                     /gene="trxB"
                     /locus_tag="ACGXWR_000588"
     CDS             46271..47197
                     /gene="trxB"
                     /locus_tag="ACGXWR_000588"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFK0802200.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            47411..49138
                     /locus_tag="ACGXWR_000589"
     CDS             47411..49138
                     /locus_tag="ACGXWR_000589"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFK0802201.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLIDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDDEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAMRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     AIIKKMTEE"
     gene            49154..49504
                     /locus_tag="ACGXWR_000590"
     CDS             49154..49504
                     /locus_tag="ACGXWR_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFK0802202.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(49598..50458)
                     /locus_tag="ACGXWR_000591"
     CDS             complement(49598..50458)
                     /locus_tag="ACGXWR_000591"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HFK0802203.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLMQALQDALKEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            50550..50978
                     /locus_tag="ACGXWR_000592"
     CDS             50550..50978
                     /locus_tag="ACGXWR_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFK0802204.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            51140..51316
                     /gene="rpsU"
                     /locus_tag="ACGXWR_000593"
     CDS             51140..51316
                     /gene="rpsU"
                     /locus_tag="ACGXWR_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HFK0802205.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            51343..51789
                     /locus_tag="ACGXWR_000594"
     CDS             51343..51789
                     /locus_tag="ACGXWR_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HFK0802206.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(51945..53324)
                     /gene="brnQ"
                     /locus_tag="ACGXWR_000595"
     CDS             complement(51945..53324)
                     /gene="brnQ"
                     /locus_tag="ACGXWR_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFK0802207.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            54030..55001
                     /locus_tag="ACGXWR_000596"
     CDS             54030..55001
                     /locus_tag="ACGXWR_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HFK0802208.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            55025..57217
                     /locus_tag="ACGXWR_000597"
     CDS             55025..57217
                     /locus_tag="ACGXWR_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HFK0802209.1"
                     /translation="MLNKTLQKLQKKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSVV
                     LMKFFQLFQTEQAAYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTVILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIIYQGMSFGD
                     ATTWLTLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYVKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKSEVEKIKEEQEE"
     gene            57234..57710
                     /gene="ybeY"
                     /locus_tag="ACGXWR_000598"
     CDS             57234..57710
                     /gene="ybeY"
                     /locus_tag="ACGXWR_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HFK0802210.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLELPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISTER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            57694..58089
                     /locus_tag="ACGXWR_000599"
     CDS             57694..58089
                     /locus_tag="ACGXWR_000599"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFK0802211.1"
                     /translation="MDLKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFSVIVGLILFVPKIYHLLFN"
     gene            58104..59003
                     /gene="era"
                     /locus_tag="ACGXWR_000600"
     CDS             58104..59003
                     /gene="era"
                     /locus_tag="ACGXWR_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HFK0802212.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            59146..59958
                     /gene="recO"
                     /locus_tag="ACGXWR_000601"
     CDS             59146..59958
                     /gene="recO"
                     /locus_tag="ACGXWR_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HFK0802213.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRHIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQLMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICERHWSMDDHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRELIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTSEKDMSEKDLPKKEE"
     gene            60344..61261
                     /gene="glyQ"
                     /locus_tag="ACGXWR_000602"
     CDS             60344..61261
                     /gene="glyQ"
                     /locus_tag="ACGXWR_000602"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HFK0802214.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            61263..63338
                     /gene="glyS"
                     /locus_tag="ACGXWR_000603"
     CDS             61263..63338
                     /gene="glyS"
                     /locus_tag="ACGXWR_000603"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFK0802215.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKESKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIDAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
BASE COUNT        20731 a        11302 c        13644 g        17710 t
ORIGIN      
        1 tttttgagtt tcctcctctt ttagatgaaa tatgaataaa ttatgaagtt cttactttaa
       61 tacgcttaag atatttcaat tatctataac taatgataaa atgaaaagta aagtctacat
      121 agtctggata atacacagaa ggaaaaggag attacacaac gcatggccaa tttgattcgt
      181 tcacttatcg aaaacgataa gaaagaacta aaacgtttag atagcattgc aaaaaaagtt
      241 gaagcatacg ctgaccaaat ggcagcatta actgatgaac aattacaggc aaaaactgct
      301 gaattcaagg gcagatacca aaaaggagaa acattagatc aattacttcc ggaagctttt
      361 gcagtcgtcc gagaagcagc aaaacgtgta ttggggttat atccatacca cgtacaatta
      421 atgggtggga tcgtgcttca cgatgggaat atccctgaaa tgcgtactgg tgaaggtaaa
      481 accttgactg caacgatgcc ggtgtatctg aatgcgttga ctggcgaagg ggtccacgta
      541 gttaccgtca atgaatattt agcaacccgt gactcgacgg aaatgggcga gctttataat
      601 ttcttaggat tgacagttgg gttgaatatc aactcaaaat cttcggatga aaaacgcgag
      661 gcttataatt gcgatatcac ttatagcacg aataatgaat taggatttga ctatttgaga
      721 gacaacatgg tcgtttaccg tcatcaaatg gtacaacgtc cgctgaatta tgccattgtc
      781 gatgaagttg actcgatctt gattgatgaa gcgagaacgc cgctgatcat ttcagggcaa
      841 gcagaaaaat caacagcttt atatacaaga gcagacaact tcgtgaaacg tttgaaagaa
      901 gaagaagatt ataaaatcga tatacaatca aaaacaatca gtttaactga agcagggatc
      961 gaaaaagctg aagaaacatt cggtttggac aacttatatg acattgaaaa tactgcattg
     1021 acccatcact tggatcaagc attgagagcc aactacatca tgcttttaga catcgattat
     1081 gttgttcaag atggaaaagt attgattgtt gaccaattta cgggtcggat catggatgga
     1141 cgccgttatt cagatggtct tcatcaagcg atcgaagcta aagaaggcgt agagatcgaa
     1201 gacgaaacga aaacgatggc gacgatcact ttccagaact atttccgtat gtacaagaaa
     1261 cttgcgggga tgactggtac agctaagaca gaagaagaag agttcagaga gatttataat
     1321 attcaagtat accagattcc gacaaaccgt ccggtcatcc gtgacgatcg accagatttg
     1381 ctttacccaa cattacaaag caagttccat gctgtcgtac aagatatcaa agatcgctac
     1441 cgcaaaggac agcctgtctt agtcggaact gttgcagttg aaacatctga gttattatca
     1501 gatatgctga atcaagaacg tattcctcat gaagtactga atgcgaaaaa tcactttaaa
     1561 gaagcagaaa tcatcatgaa tgcgggtcaa aaaggtgcag tgacgattgc taccaacatg
     1621 gctggtcggg gaacagatat caagctaggg cttggcgtaa gagaacttgg tggcctagca
     1681 gttatcggga cagaacgaca tgaatctcgt cgtatcgata accagcttcg aggacgtgca
     1741 ggacgtcaag gagaccctgg tatgtcacaa ttctacttgt ctttagaaga tgatttgatg
     1801 aaacgattcg gttcagaacg aatcaaagct ttcttagatc gaatgaagat cggtgacgaa
     1861 gatgctgtga tccaaagcaa gatgctgacg aaacaagtag aagctgcaca aaaacgcgta
     1921 gaaggaaaca actacgacac acgtaagaac gtcttgcaat acgatgacgt gatgcgtgag
     1981 caacgtgaag taatctataa acagcgtcaa gaagtgatca tggaagaaaa aagcttatct
     2041 aaaccactga tgaatatggt caaacggaca atcagtcgtg tggtagatgc gcatacgcaa
     2101 ttagaaaaag aaaattggaa tttggaaagt atcgtcgatt ttgctggcag cacgcttgtc
     2161 catgaagaca gtatttccct tacagatatc gaaggaaaaa cctctcaaga aatcaaagaa
     2221 tatctaaacg aacgagcaca agaagtattc aataccaaag cagctcaatt gaacggacca
     2281 gagcaactgc ttgaatttga aaaagtcgtg atcttacgtg tcgtggactc taaatggaca
     2341 gatcatattg atgcaatgga ccaattacgt cagtcaatcg gcttgcgtgc ctatggtcaa
     2401 aacaatccat tagtcgaata ccaaacagaa ggttataaga tgttcgaaga tatggtaggt
     2461 gccattgaat atgaagtcac tcgtatcttc atgaaagctg agatccgtca aaacgtacaa
     2521 cgtgagcaag tttctcaagg aacagcttct cactcagaag atggagatgc caaagaaaac
     2581 agtaatacta gcgcgaaaaa acaaccaatc catgtgaaca aggttggtag aaatgatcct
     2641 tgtccttgtg gaagcgggaa aaaatataag aactgtcacg gaaaagatgc aaactaattt
     2701 ctgacagcag gattggtgag acaaattctt ttttaaagaa tttgtctcac cttctttctg
     2761 ttatttgacg attctgttag actagatata ataaaaaaag tatagtgaaa gaaggaaaaa
     2821 aacatggaaa tatccgaaat tcgaaatctc ctgacagaaa tgcaggaaaa ggtcacaagc
     2881 ttcaggaggt ctctttgact tagaccagct ggaagaagac attgcggaag cagaagcaaa
     2941 aatggctgaa cctggttttt gggatgatag cgaagctgct caaaaagtga tcagtgaaaa
     3001 caatgcaaat aaagaaactt atgatcaatt ccattctctt gctgaagaac tggaagaaat
     3061 cgaattgatg gtggagatgt tgcaggaaga acctgatgca gtaatgcaag aagaagcaga
     3121 agcacgtatc aatgcgctag atgaaaaaat gaatacgtat gaattatcta tgttgttaga
     3181 tggtccttat gatcgaaaca acgccatcgt cgaattgcat ccaggggctg gcggaacgga
     3241 gtcccaagac tggggcagca tgcttttacg catgtataca cgctgggcag agcagcatgg
     3301 gtatcaagta gagacactag attatcaagc aggcgatgaa gcaggaatca agagtgtgac
     3361 cctactgatc aaaggacaca acgcatttgg ctatctgaaa tcagaaaaag gtgttcatcg
     3421 ccttgtacgt atctcgcctt ttgactcagc aaaacgtcgt catacttctt tttgttcggt
     3481 agatgtgatg ccagagcttg atgaaacgat cgatatagaa atcaatccag atgatttgaa
     3541 gatcgacaca tatcgggcga gtggtgcagg tggtcagcac atcaataaga cagaatccgc
     3601 tgtacgaatc actcacttgc ctacaggaac agtagtagcg agtcaggcac aacgttcaca
     3661 attgaaaaac cgggaacaag cgatggggat gctgaaagct aagctttacc aattagaagt
     3721 ggaaaagaaa gaacaagaag cagctgcact gagaggagaa caaaaagaaa tcggctgggg
     3781 atcacagatc cgttcttatg ttttccatcc atattctatg gtaaaagacc atcggacaaa
     3841 cgtagagaca ggaaatgtcc aagctgttat ggacggagat cttgatttat ttattgacgg
     3901 ctatttgaaa atgcatctgc aataagagcc ctttgttaaa ttgaaataaa attgtaagat
     3961 tttgcaagca agttgaaaca ttgccatgct ataatagcta aagactgaaa aagatatgga
     4021 gagaacgcca tgattgaaat gaaggatgta atgaagaagt actcaaacgg taccactgct
     4081 atccgcaatc tctcgattgt catcgaacaa ggagagtttg tgtatgttgt tggtccgtct
     4141 ggagctggta aatctacatt catcaaattg atgtatcgag aagaaaaagc ttcaaaagga
     4201 actttgaacg tcgcaggtca tgatctaata gccatcaaaa accgcgaagt tccttatcta
     4261 cgcagagaaa tcggcgtggt gttccaagac tataaattat taccaagaaa aacagtatat
     4321 gaaaatgttg cgtacgccat gcaagttatc ggcagaaaac ctcgggatat caaaaaacga
     4381 gtaatggaag tgctggatct tgttggtttg aaacacaaag tccgagtctt tcctagcgaa
     4441 ttatctggtg gggaacaaca acgtgtttct attgcccgag caatcgtaaa tacacctaaa
     4501 gtacttatcg cggatgaacc gacagggaat ctagatccgg aaaactcatg ggaaatcatg
     4561 aaactattag atcggatcaa tgcacaagga acaactgtcg tgatggctac acataacagt
     4621 acgatcgtaa atacgattcg acaccgagta attgctatcg aaaacggccg cattattcga
     4681 gaccaagcgg aaggggaata tggatacgat gattagaacc tttttccgcc atttattaga
     4741 aagtatcaag agtttgaaac gtaacggctg gatgacagta gcttcggtca gtgcggtaac
     4801 gatcacgttg actttagttg gtgtgttcat ggcggtcatc atgaacgcaa ccaaactagc
     4861 acaagatata gaaggaaacg tggatgtatc tgtgttcgta gacattggta caaaagacga
     4921 agagatgaaa aaattagaaa aagaattaaa tgacttagat catgtcaaaa aagtcgaatt
     4981 ttcaagcaaa gaacaggaat tgaagaaaat ccaaaacgaa atgggcgatt cttggaaatt
     5041 gtttgaaggg gataataacc cgttatatga tgtatacgta gtaagtgcta ccgatccttc
     5101 ttatacaaaa caagtagcag aaaaagcggc agatttgaag aatgtttccc gttctgatta
     5161 cggtggggct tcctcagatc ggattttcca aattgctggt gcagttcgaa catggggatt
     5221 agttgcggcg gcattgctgc tgtttgtagc aatgtttctc atttctaaca cgattcggat
     5281 cacgatttta tctagacagc gtgaaattca aatcatgcgt ttagtagggg caaaaaatgg
     5341 atatatccgc tggccatttt tccttgaagg tggttggatc ggcttaatcg gtgccattct
     5401 tccgatactg atcattacat ttggttacgc atggttttac caattgatca atccgtcatt
     5461 attacgatct cattattcat tgatccatcc agaaaatatc gtttggaaaa tcaatctttt
     5521 gatggtcggt attggtgtga tcattggttc actcggctcg atcatctcta tgagacgttt
     5581 cttgaaattc tagtgtcaca agataaatat aatcagaaag ttggacgatt tcgttccagc
     5641 tttctttttt tatcagctag gtggagtaaa tggggcggct tttttctctt tactttaaaa
     5701 aacaacttgg gtattcttaa gttggtagaa aaagaggtga agccgtgaag attatcgttg
     5761 acaatttttt tacgatcctt ttgattatga atattttgct ttcctttatt atcgtttttc
     5821 gagaaagaaa ggaaactgcg caaacatggg catggctgct cgttttgatg ttcattccag
     5881 ttgtaggatt tattttatat atttttttag gaagagggat ttccaaagag aaaatctttg
     5941 atttgaagat ccaagggaaa atcggtaaga atctagaaat cgaagaagat aaacaagcat
     6001 tgatgcgagg gctttatcct catccgccta ctggacaagt agatgtgaaa caattgatct
     6061 atatgcttac tgtatttgaa agtacgcttt atacgactaa aaatgaaatc actttattta
     6121 cagatggtcg tgaaaaattc gatgcgctga tcgaggatat caaacaggca gaagaccata
     6181 tccatttcca atattatatt taccgcagtg atacattagg tgaagaagtt cgagaggcat
     6241 tgacagaggc agcaagacgc ggagtaaaag tcagagtcct tcttgatgca tggggttcca
     6301 cacaagtttc ttctagtttt tttcagaatt tgaaaaaagc aggtggagaa gtcgcatttt
     6361 tctttcctct attcgttccg tatatcaatc ctcgaatcaa ttatcgcaat catcgtaaaa
     6421 tcgtagtgat tgatgggaaa atcggatata caggtgggtt caatgttgga aacgaatatc
     6481 taggattggt aaagaaattt ggttattggc gagacaatca tctgcgtatc tatggagaag
     6541 cggtttacac cttgcaaaac cgttttttga tggactggaa ttctcagcat acaaaagaag
     6601 taggatattc accggaattt ttcccgacca ttcattctac aggtgatatg gctgttcaaa
     6661 tcgtgacaag cggaccagat accgaacatg agcaaatcaa aatgacatat ttgaaaatga
     6721 tttcgttagc caaacgggag atattgatcc aaacgccgta ttacataccg gatggatcga
     6781 ttcatgaggc attgaagttg gctcttctct caggcgtaaa agtccatatc caaataccta
     6841 acaaaccaga tcatcttctc gtttactggg caacgtattc tttcgctgca gagctgatcg
     6901 agtatggggc aagaatcgaa acatatgaaa atggatttat ccatgcaaag acgatgatta
     6961 tcgatggcgg catcgtttcc gttggttcag ctaatatcga cgttcgctca tttagattgg
     7021 attttgaagt caatacactg atctatgatg aacgaatggc ttctcgcgta agaaaagcat
     7081 tctttgaaga ttcaaagatt tcgacgcatc tcacaaaaga agtgtatgaa aaccgaggga
     7141 tgatgatcaa gatgaaagaa ggattagcaa gactgatttc gccgctcctt taaaatacaa
     7201 aaaggacagg agagccatca atagatggaa atctcgcgtc cttttttctc ggggccattt
     7261 ctgagagtac gtcagaaatg gagaaagcgt ctcgcatgag cgaaattaac tttggggtat
     7321 ctcttgtttt ttggggaaag caagaaataa gctaatatat gctattaaaa gagacacatt
     7381 tcaaagccag tatagcatag aaacttttaa tgagatagct ttttttgcaa ttatgagaat
     7441 ttattttgtt atttaatgat tttgattcgt tttcatcaag taatgaaaat gatagaataa
     7501 acatacttta ggattaaagg agatttctaa tgaaaaaact aaaattattc ttaccaataa
     7561 taggattagc tattctttta tcaggctgtt caaagtggat tgatcgagga gaatccatta
     7621 ctgcagttgg ctcttctgcc ttacagcctt tagtagaaac ggttgctgaa acctaccagg
     7681 cagaaaatcc tggaaaattc atcaatgtac aagggggcgg aagcggaact gggttgtctc
     7741 aagtacagtc aggagcagtc gatatcggaa attctgattt gttcgcggaa gaaaaatcag
     7801 ggattgatgc ttcggcatta gtcgatcatc gagtagcagt tgttggaatc actcctattg
     7861 tgaacaagga tattggcgta aaagatatca gtatggaaaa cctgaaaaaa ttatttacgg
     7921 gcgagatcaa aaactggagt gaagtcggtg ggaaagatca gccagtagtt atattgaacc
     7981 gtgcatcagg aagcgggacc cgtagtacgt ttgaaaaatg ggtattggac ggagaaacag
     8041 ctgttcaggc acaagaacaa gattcaagcg gaatggtgcg ccaaatcgtt gcggacacac
     8101 ccggagcaat cagctatgtt gctttttctt acgtttccga tgatgtggat acgttgaacg
     8161 ttaacggtgt ggaaccaaca gatgaaaatg tgacaacgaa caaatggacg atttgggcat
     8221 atgagcatat gtacacaaga gaccatccaa aaaaactgac aaaagaattt ttagactata
     8281 tcttatctga tgaagtacaa gataatattg tcggagagct aggctatatc cctgtttcac
     8341 atatgaaagt tgaacgtgat tggcaaggaa acattgttaa agagtaatct ttacacaaaa
     8401 tttacaaact tagctaaact tttacatgtt attaaaacca aattgatgtt caatttgtac
     8461 actgagtgag tatgttaaac ctgattaagg gggagtcatc tgtggaagat gtgaaaaaag
     8521 tattattaac aaaatcaaaa cgttcaaaaa tggaacagcg cggaaaattc attagttttt
     8581 tgtgtatcgc gctgatcgtg ttggttgtat tatctatttt ttattttgtc gctagtaaag
     8641 gattggccac cttttttact gataagatca atgtatttga ttttctgttt ggtacagatt
     8701 ggaatccaag ccaaatagga gcaaatggga aacccatggt aggggcattg cctatgatca
     8761 caggttcatt tattgtgacc tttttatctg ctattgttgc cacaccattt gctattggag
     8821 cagcagtgtt catgacggag atttctccta aaaacggaac gaagatcttg caaccggtca
     8881 tcgagctact tgtaggtatt ccgtctgtcg tttacggatt tatcggttta tctgttatcg
     8941 tgccttttgt cagaagtatc tttggcggga cagggttcgg tatcttagct ggtacatttg
     9001 tgttattcgt tatgatctta ccgactgtca caacgatgac tgtggatgca ttaaaggcag
     9061 tgccgcgaca ctatcgggaa gcttcattag cgctaggtgc cacaagatgg caaacaatct
     9121 acaaagtggt gctgcgagca gcagtgcccg gaattttaac agcagtcgtt tttggtatgg
     9181 ctcgtgcgtt tggcgaagcc ttagctatcc aaatggttat tggtaatgcg gcattaatgc
     9241 caacaggact tactactcct gcttctacat tgacgtccat cttgacaatg ggaatcggaa
     9301 atacaatcat gggaacagtt gaaaataatg tgttatggtc attagcgctg atcttgctat
     9361 tgatgtcatt attctttaat atcgtgatcc gtatgattgg gaagaaagga gagctgaaat
     9421 aatgaacgca aaacgctcag ataaaattgc tacaggtgtt ctatatgtgg tttcagggat
     9481 catcgtattg atcttagcag ctttattact ttatatctta gttcgaggaa taccgcacat
     9541 ttcatggtca ttcttgactg aaccttccaa agcctaccaa gaaggcggtg ggatcgggat
     9601 tcaattattt aactcgattt atttgctttt gattaccatg atcatcagtt ttcctatctc
     9661 tttaggtgcg ggtatctacc tttcggaata tgccggaaaa aactggctga cagacgtgat
     9721 ccgtacgtct atcgaaatct tgagctcttt gccttctgtt gttgtcggtt tattcggttt
     9781 cttggttttc gttattcaat tccagtatgg tttctcaatc atttctggtg cattagcttt
     9841 gaccgtattc aacttgcctc ttttgactcg aacggtcgag gaatctttac aagcggtcca
     9901 ttacacacaa cgagaagctg gattggcgtt aggtttgtca cgctgggaaa cagtgataaa
     9961 agtggttgtt ccagaagcga caccaggaat tttgactggt gtgatcctaa gttcaggaag
    10021 aatttttggt gaagctgccg cattgattta tacagctggt caaagcgcgc cagcattaga
    10081 ttttacgaac tggaatccat taagtgtttc tagtccgatc agcattttcc gccaagctga
    10141 aacactggct gtccatattt ggaaaatcaa cacagaaggt acgatgcctg atggtgtttc
    10201 tgtttcggct ggcgcttctg ccgtgttgat cattgctgtt ttactgttca acttcggcgc
    10261 tcgtgcgatt ggcaaacgat tataccgaaa aatgacttca gcctaaggag aagaagtaaa
    10321 atgaaaaaat ataattggaa tgaaacaaat gtcattacca tgccaaaaga taaggaagtt
    10381 gcattatata cgaatgatct gcatgtttgg tatggcgaca atgaagcaat caagggagtg
    10441 gatctagaat tcgaaaaaaa taagatcact gcattgattg gtccctctgg ctgcggaaaa
    10501 tccacgtatc ttcgttcttt gaatcgtatg aatgatggga ttgctaatac gaaaattact
    10561 ggaaagatta tgtataaaga cgtggatatc aatgcgcctc aagtggatgt ttatgaaatg
    10621 cgtaaacgga tcggcatggt gttccaacgc cccaaccctt ttagcaaatc gatttatgac
    10681 aatataactt ttgctttgaa acagcatggt gaaaaaaaca aaaagaaatt agatgaaatc
    10741 gttgaaacaa gcttgaaaca agcagctttg tgggatcaag taaaagatag cttggataaa
    10801 agtgccttgg ctttatctgg cggacaacag caacgtttgt gtatcgctcg tgcaatcgcg
    10861 atgaaacccg atatcttgct gttagacgag ccggcaagtg ccttggatcc tatttcgaca
    10921 ggaacggttg aagaaacact tgtaaacttg aaagaagact acacgatcat tatcgtgacg
    10981 cataatatgc aacaagcagc tcgtatcagc gactatactg cctttttcta tctaggaaaa
    11041 gtaatggaat atgacaaaac aaacaagata tttaccagac caaaaattca ggcaaccgaa
    11101 gattatgtgt ccggtcattt tggttaagac ggaggcctca acatgacaaa agaaattatc
    11161 tcatccaaag atcttcatct gtattatgga aagaaagaag cactaaaggg aattgatcta
    11221 agtttcaatc aaggtgaaat cacagcgatg atcggtcctt ctggttgcgg gaaatctacc
    11281 tatctacgtt cgttgaatcg aatgaacgat ctgattccaa atgtaacgat caccggaagt
    11341 gttttatata aagacaaaga catctatggt ccgaaaacag atgttgttga actaagaaaa
    11401 gaaatcggca tggtgttcca acagccaaat ccatttcctt tttctattta tgaaaatgtc
    11461 atctatggat tgaagttaaa aggtgaaaaa gataaaaaag tccttgatca agtagtggaa
    11521 gaaagtctga aggcagcgtc cgtttgggag gatgtgaaag ataaactgca taaaagtgcc
    11581 ttgtctttat ccggtgggca gcagcagcgt gtatgtatcg cacgtgtttt ggcagtgaat
    11641 cccgaaatca tcttattgga cgaaccaaca agtgcacttg accctgtttc tactgggaaa
    11701 atcgaaagta tgctgttaga attaagagag cggtatacga tgatcatcgt gacccataat
    11761 atgtctcaag cttcacgtat ttcagataag acggcattct ttttagatgg tcacttgatc
    11821 gaatacaacg atacgaagaa gatattcatg aatccagaaa aacaagagac agaagattat
    11881 atttcaggtc gatttggata aggaggaaac ggaatgctac gtacacaatt tgaagaagaa
    11941 ttgctgaatc tccataatca gttctacgaa atggggatga tggtgagcag cgctgtgcac
    12001 aagtcagttc gtgcatacat caaacacgat aaaatcttag ctcaagaagt tatcgaaaac
    12061 gatataaata tcaataatat ggaaacgcgt ttggagaaga aaagttttga aatgattgca
    12121 ttacaacagc cagttacaac tgacttgcgt atgattatca cggtcatgaa agctagctct
    12181 gatttagaac gtatggccga tcatgcggtg tccgttgcta aatccacaat ccgcgtaaaa
    12241 ggacagacga gaataccgga aatcgaaaaa gagatctccg atatgtccga ttacgtgaaa
    12301 aaaatggtgg acaacgtcct agttgcgtat gtcaaaacag acgaaaaaga tgcgcgtaca
    12361 atcgccaata tggatcaaag agtcaatgac tatttcaatc gaatctataa tgcaaccatc
    12421 aaaaacatgc aagaaaatcc tgaaacagtc atcagtggca cagactattt gaatgttgcc
    12481 agctatctag aacgaatcgg agactatgtg acaaacatct gtgaatggat cgtctacttg
    12541 gctacaggga aaatcactga attaaatacg aaccacaatg agattttcta aactgaagtt
    12601 gtgattctgc tgtttattta ggaaaagagg ttgtgaaatc agcgttttgt cctgagtatt
    12661 agagaaacaa acggtaaaat agttcctcat attttgccgt tttttgagct aataccgaag
    12721 gtcagctgat tgaacaccgt ttattctgga aaagggtttg tgacaaaaca tgtcacaaac
    12781 ccttttcatt attccaatag aaaggataaa gaatgcaaaa aaagattagc atcatcatca
    12841 ctctattttt tatttgtata cttgcttcat ggtttattca gcgtcaagct gctctatatg
    12901 acgtacctgt catcgagatc gaaagagtga gaatagaaga ggatcaacaa ttgattacag
    12961 gaagattgat gaatacggac caaaaaggag aagtgatttc tttaacggct ccttatcaaa
    13021 aaaatcaaat cgaaacagca aatataacaa caagacaaat ctatcttgtc caaatgcatg
    13081 gagatgaatg gcaactagta gcaaaaaaaa atgatggctg gctttttttc tttacaagtg
    13141 tcttcattgg caccatgttg cttattggtg gaaaacaggg cgtatttgct ttaggaagtc
    13201 tcatcatcaa catcgtttta cttttacttt tgttgctcct ctttaccaaa acagaaggta
    13261 tttctctctt aaatatagca atcttatttg tcgttatagg gataatcgtt agtatattgg
    13321 cgttagacgg atggaataga agcagtataa tcaaaatttc ggctgcagtt acaagtgttt
    13381 ttttagcatt ttttatttgt cttttgacaa tgaatcattg gaaagatcaa ggactgcgct
    13441 atgaagaact gaattatctg acacgaccgt atcgttctgt ttttctttcc agcgtgctga
    13501 ttgggacagc tggagggaca ctcgataccg tgatcacagt cattgcgaca ttagaagaat
    13561 tgaccaagca acaaccgaaa atatcagcga aacagttatg gctttcagga aggcaagtgg
    13621 gccgagatgt gattggttcg atggctaata tccttttatt cgtctatatc agcggagcga
    13681 ttccatcgct tctgttatat ttaggaaatc aatggtcttt caaagaaacg gtagaacgac
    13741 atttatcatt agaactttta cgcgtcattg ctggcagctt aggaatagta ttatcaatcc
    13801 ccatcgcggt cctctttttt ctcgctgtaa ggaggttaaa aaaatgaatg tacttattat
    13861 acttgttggg atttttgcaa tcagtgtgct atttgtcggt ggtacgcaag gtatgtatat
    13921 tcttttagga ttattcatta atttaggaat ctttttccta ttattattcg gctatcatca
    13981 gaagtggccg atattggtat tgtcgattat agggttccta ttgatcgctg tggttatctt
    14041 attttttatc aatggttata atctgaaaat gcgagccgct tttgccagta tactgatctt
    14101 tttgttttgt ttcctactat tgattcctat cactgatttt ttagcgatcc aaggctttac
    14161 ttcgatagaa ctagaagaac tatctggctt agataagacg ttagcaattg attttagact
    14221 acttacgagg tcgttgcttc tgatcagtct tagcggagct gttttagatg cgagtgtagc
    14281 gatttctagt ggaacattcg aagtatatca ggcaaatccg caaatgtctt ttaaccaatt
    14341 gcgccatgct agctttgcca ttgctaaaaa aatattggca tcaacagtga tgacgcttct
    14401 ttttgcgttt atggggagtt ctttagcgtt gattctttgg tttattgact tagacatttc
    14461 ttttcagcaa ataatcaatg aaaaatcatt tgtcttggaa tatacgatgg ctattcttac
    14521 cacactggcc gcactacttg tcctgccctt aacttgcgtg actacagcat atctctttac
    14581 aaaaaagaaa gaacatctca agatggagta aaagttacaa cttaagtcct atgacatttt
    14641 tactgaatca gtgcataata tggatgtaag gaaaagcttg caaacaattt tgcttaagga
    14701 ggcaatttcc atgaaagaaa gagaacgtat tttagactta gtgaaaaaag gaatcctttc
    14761 gactgaagaa ggcttagatt tattagaaag catggcaact gaaaaagacg aaaaacaaat
    14821 caaaaaagaa gcagacaagg taactgctag tcataaagaa aaagatcagg caagtcaatt
    14881 gatcgatgaa cttgaaaaca gtgaagaaaa aatttctgag ccagttgatc caaaagaaaa
    14941 agaaagacaa gatcaagaaa acttagaaaa gatcttagat gaactagcaa ctgaagcgaa
    15001 taaaacttcg gcgcgtctag acgaagtaaa tgctcaattc gctgacaata aggcagcacg
    15061 taatgagaaa caggaagcat tgatgcagct gaatacaaaa gaagaattag gcgagttgac
    15121 agaagaagaa ttagcacagc gtcaaacgtt agaagcagaa atcaaagagt tagaagcaac
    15181 cggcgataca ctattagaag aacaattgaa gctggaagca gaattaaaag atatccgcaa
    15241 gaatcaatgg tctgagaaaa aagaaacatt tacggataag tttgaattgc cagatgattg
    15301 gaaagatcaa gcgacagata cgctgaatca agtaggcgaa aaaatgtcag aagctggatc
    15361 acagttaggc aaattcttga agaaaacatt ccaaactgtt tcagaaacag taaatgataa
    15421 catggaatgg aaagatgtca gcttacgcgt ccctggaatt gcgacaacga aatttgaaca
    15481 cgaattttat tatgaagctc ctgcagcaag tatccttgat atcaaggcag caaacggaaa
    15541 cgtgacgtta aaaacgtggg acagtgatga tgtgaaagtg gaagccaaga tcaaacttta
    15601 cggaaaaatg ggtgctgaac catttgaagc attctctgaa cggagccaga tcgaggtcaa
    15661 tgaagatcat atctccttcc aaattccaaa taagcgtgtg cgtgcagacc ttgttttcta
    15721 cttgcctaaa cgagtatacg accatgcagc tatcaaactt ctaaatggca acatcatgat
    15781 tgagacattg gaagctaaag atatttatac aaaatctacg aatgggaaca tcatcgtgaa
    15841 ccaattaact gcaacgatgc tggaagtaga aggtgtaaac ggcaatatcg atattcgaaa
    15901 cgggaacatc ttagattcta ttatagaaac agtaaacggt acagtgacat ttggtgccac
    15961 accagaaaac ctttctgtgt ctttagtaaa tggtgatgta cgtcttacga ttaaagaaga
    16021 taatttgaaa aaagtagaag caagttcagt gaacgggaat gtcaaagttg ctttaccaga
    16081 tagcatcggt ttggaaggac acgctaaaac aagtcttgga agcattaaca gccgtctgtc
    16141 caattacgaa gtagttcgtg agaaaaaaga acggacaaac caaatgttgc aattccgtcg
    16201 tgtttcagat gatgagatcg cacaagtgca gctttcaacg acaacaggaa gtatctattt
    16261 aaaagataca gataaataaa gaggttgtga aagagatgtt cagccttgag caataagaag
    16321 cgatttttta aaatagcttc ccctatttta aaaaaatgtg ccttattgcc gataggctat
    16381 ctcttgaaca ccgattaaga agaaggttgt cacaacgatt ttcttcattt aaaatagtag
    16441 aacagaggtg agacatgatg aaaaaaaagt tgacaaaatc caataaaaat gttgttttga
    16501 caggtacttt agcagggatt ggggaatata tcgggattga tcccactgtt atccgtgtgc
    16561 tttatgtatt cttaagctta gttgcttttg gaagtccaat cattttatac attttattag
    16621 ctttgattat cccatctgcg cgttctgcac gaacaaacta tggacataac aatgcatatt
    16681 atgaaaaaaa caattatcgt gaacaaacaa aaaaacgcaa agaagcggaa aaaatcgatg
    16741 atgacgaatg gagtgacttt taatgtcgta ctttcagcgt attttggtta atacgttaac
    16801 attcatatcg ttggctgttc tttttcctgc gatggtccat gtgagcagta tttggacggc
    16861 cgtccttgcc agcttcgtat tatctgtgtt gaacatgttt gtcaaaccga ttttgacgat
    16921 cctgtccctg ccctttacat tagtcacatt gggattgttt acgtttgtta tcaatgcagc
    16981 gattcttaaa atgacttcct tttttgtagg agcagaacat tttagttttt cttcatttgg
    17041 tgcagcgtta ttcgtagcta tcttgatgtc acttgtcaat gtaattgtta gtgaacataa
    17101 cagcagaaaa taaaaaaagc tgtgccgaga tctcggcgca gcttttttgt ttagaataaa
    17161 gaatgcgttt tctattacat tggtaattaa ataaaaacgt tttttttaat tggtagtact
    17221 tttggctaga caatgataaa atgatagaga acactctaat agaaatgagg tagcatgaat
    17281 gtcagaagtt gtaaaagtta gccaattagt aaaaaaatta tctttggaaa tcgtcacagg
    17341 cgacgagaaa agtttagacc gcgtcatcgt gactggggac atctcacgcc caggactaga
    17401 gttgaccggt tattttaatt attattccca taatcgttta cagctatttg gcagtaaaga
    17461 aatcagtttt gcggaacgga tgatcccaga agagcgtttg atcattatga gaagattatg
    17521 tagtgaagat atgcccgcat ttattatttc aagaggattg ccggctccgg aagaaatgat
    17581 ccaagcagcc aatgaaaatg ggatagctgt gctgcgttcg cctatctcaa cgtcccggct
    17641 gctaggtgaa ttatctagtt atttagatgg acgcttagcc cctcgaacaa gtgtccacgg
    17701 tgtgttagtc gatgtctacg gattaggtgt actaattcaa ggggacagtg ggatagggaa
    17761 aagtgaaacg gcgttggaac tgattaagcg cggacatcga ttgatcgcag acgatcgagt
    17821 agatgtctat cagcaagatg aactgacggt aatcggagaa cctcctaaaa tcctggaaca
    17881 tctgattgag attcgaggga tcggtatcat agatgtaatg aatcttttcg gtgcgagtgc
    17941 ggtacgaggc tctatgcaag tccagttagc tgtttatcta gaagcatggg cgaaagataa
    18001 gaaatacgac cgtctgggct ctgaagacac gaccgttgaa atcgcggaag tgggcattcc
    18061 acaaataaaa atccctgtca aaacaggacg aaacgttgca atcatcattg aagtagccgc
    18121 aatgaatttc cgcgcacgta caatgggctt tgacgcaacg aaaacatttg aagaaagatt
    18181 aagtcgcttg attgaagaaa actcaggcaa tgactagcaa ggagtgacaa tatgttagca
    18241 caaatcaatc gagttgcttt tgagcttgta ggaattccta tctactggta tgcattgatt
    18301 atcgtatcag gaatcattat tgccatgtgg ctcagcagca gagaagctgt tcgggtagga
    18361 ttaaaagcag atgacgtgac agattttatg ttgtggggat tgccgatttc cattattggt
    18421 gcccgcttgt attatgtttt attcgatctt ccccaatata tagctgatcc aatccagata
    18481 ttcaatatcc gttcaggagg attagcgatt tacgggggat tgattgcagg tgcaatcaca
    18541 ctgtactttt ttaccaaata tcattttatt tctttgtgga cctttttaga tatcgctgca
    18601 ccaagcgtat tattggcgca ggcaatcgga cgatggggaa atttcatgaa ccacgaagcg
    18661 tatggtccag acacgacacg aagtttctta gaaagtctgc atttaccgca attcatcatt
    18721 gataacatgt atatcgaagg aatctatcga caaccaacct ttctttatga atcactttgg
    18781 agtttgattg gatttattct gcttttggtt ttgcggaaga aaccacatct tttgaaaaaa
    18841 ggagaagtcc ttttatgtta tctaatgtgg tatagtttcg gacgtttctt tatcgaaggg
    18901 ttacgcacag acagccttta ctttttaggt gtgatccgca tttctcaatt attgtctgct
    18961 gttttatttg tcggcacatt gattctgttt atttggcgta gaaaaaaagg aagtttaccg
    19021 gattatgacc gctcattagg aaaaaatcaa caaattattt gattttcaga gcgttaaaaa
    19081 tgaaaaaaat ttcaggagtg gtaaaatgaa ttatagagta gcggttttag gaccaggctc
    19141 ttgggggact gctttagcac aagtcctcgc tgaaaacgga catgacgttc ggatttgggg
    19201 acatcgtgct tcacaagtag aagaaatcaa cacccaacac accaatcaac gttatttacc
    19261 agatcatcat ctacccgatt ccatccgagc attcaccgat atggaagatg cagtaaaaga
    19321 tgcagatgcg gtactattcg ttatcccgac gaaagcgata cgttctgttg caaaagaact
    19381 agttgccaaa ttgaatacga agccagtgat catccacgca agtaagggat tagaacaggg
    19441 aacgcataaa agaatctctg aaatcttgtt agaggaaatc ccgacagaaa aaagaaaagc
    19501 tgttgctgtt ctttctgggc caagccatgc ggaagaagta gcaaagcatg acattacgac
    19561 gatcacagcg gcaagcacaa atgtaaaagc agcaaaatat gtacaagagc tgttcatgaa
    19621 ccattatttt cgaatctata ccaaccctga tgtgattggt gtagagatgg gagcagcttt
    19681 gaaaaatatt attgccattg gagctggtgc tattcacggc ttagggtttg gcgataatgc
    19741 aaaagcggca atcatgacgc gcggattagc tgagatcagc cgtttaggtg tagcaatggg
    19801 tgccaacccg ctgaccttta ttggcttaag cggagtaggt gatctagtcg ttacttgcac
    19861 aagtgttcat tccagaaact ggcgcgcagg caacttgtta ggacaaggtc agcctctaga
    19921 agaggtgcta gccaatatgg gaatggttgt tgaaggtgtg aatactactc aagcagcgat
    19981 ggaactagcc caaatgatgg aaatcgaaat gcccatcact caaacaatct atgaagtgct
    20041 gtatgaacaa aaagaaatca aaacagccgc aaaagaaatc atgttacgtg atgggaaaaa
    20101 agaaaatgaa ttctcattaa caattttttg aaggagcgaa tgtatatgaa agtaaaaaaa
    20161 gcagttattc cagcagcagg attaggaaca agatttttac cagcaacaaa ggcgatggca
    20221 aaggaaatgt tgccaatcgt ggacaaacca acgatccaat tcatcgttga agaagcgttg
    20281 aaatcaggaa tcgaagacat cttgatcgtt acaggaaaag ctaaacgacc aatcgaagat
    20341 cactttgatt caaatatcga attagaaaca aacctaagtg aaaaaggaaa aaccgaatta
    20401 ttgaaattag tagaagaaac gacagatgtc aatttgcatt tcatccgtca atctcatcca
    20461 aaggggttag gacacgccgt tcttcaagca agagccttta ttggaaatga accgtttgtc
    20521 gttatgctag gcgatgatat catggaagac gaagtaccat tgacacagca attgatcgat
    20581 gactatgagc gtacacacgc ttctacgatt gccgttatgc aagttcctca cgatgaaact
    20641 tcaaaatacg gaatcatcaa cccaggggaa gtactggaag atgggttata caatgtcaaa
    20701 aactttgttg aaaaaccaga tccaagcaaa gcaccaagtg atttagctat tattgggcgt
    20761 tacttattga ctccagaaat ctttgatgta ttatcagaac aacaaccagg cgctggaaat
    20821 gagatccaac taactgacgc aatcgatacg ttgaataaaa cacaacgcgt atttgcccgt
    20881 aaattcacag gtaaacgtta tgacgttggt gacaaatttg gttttatgaa aacaagtatt
    20941 gaatatggtc tgacacatcc agaagtaggg gcacctttgc gtgaatacat catgtcttta
    21001 ggtaaaacat tagaagcaga aggaagcaag atcaatcata atccaaaagg aataacagaa
    21061 atcaaagaag aaaagaaaaa ataatctttt tttctaacga gcttcagctg ctaattgaat
    21121 aaaaagtagt tgaagctcgt ttttatttgt ttaaaaaaca cgaaaatgct atccttatag
    21181 aaaagagaga caagaaggga gtttgatcat gtcaggagga gaaattgcag gattgatcgc
    21241 agcaatcgcc tttgcgatac ttgtcgtttt catcgttcgc gtattgttgc aagtttccaa
    21301 aactttagaa aaagtagacc agactgtcgc agaagcaaat acgacaattg agatcgtcac
    21361 acaagacgta gatcttttat ctagacaagt agaaggcttg ctagtcaaaa gtaatgagct
    21421 gctcttggat atcaatggaa aagtcgcaac gatcgatcca ttgttcacag cagttgctga
    21481 tttaagtgaa agtgtatcgg aacttaatca ttctagtaaa aacatcgtga cgaaagtcgg
    21541 cggaatcgga aaaacgacag ctaaagcgac tgttgccgga aaagtcggtg gaacagcgat
    21601 gaaattttta aaaacaaaaa acatactgaa acgacaggag gaaaataaga atggctaaaa
    21661 aaggtggatt tttattaggt gcagtagttg gaggtacagc cgcagcaatc gccgcattat
    21721 tgttagcacc caaatctggt aaagaacttc gggatgaatt ggctgctcaa gcagatgatt
    21781 tgatggacat ggcttcagat tacacagata tggcaaaaga aaaatcatct gagttaacag
    21841 gtattgcaaa agaaaaagcg caagatcttt ctcaacaagc aggggatcta gcaggcaatg
    21901 ttaagcagaa ggtaagtgaa tcagcagagg aagcaggaag cgaatcagat gatatcttgt
    21961 taaacctcaa agaacaatca gctgatttat ctaatcgttt caaaaaaaca gcagaagatc
    22021 tgaaaaagcc agcagacgaa ttaggtagta ttgctaaaga tacttcagaa gatatcatga
    22081 tcgatgtaaa agatgctgca gataaagcag gagagacggt caatgaagga atgtcagaag
    22141 caaaaccagt tgcagatgac acaaaagaaa tgttgaaaat ggcaaaagaa gatgcaaaag
    22201 aagctaaaaa agaaatgaaa gatacaatga cagattcgac taccaatcac taagattact
    22261 catttctaga ataaaaaagg tgagagcgga ccagctctca ccttttttat tttcattact
    22321 ctaaaacaag taattctttt ggtgtagtcg tgaatggcac acaaccatca cttgtcacat
    22381 acacacaatc ttcgatacgt acccctactt tttcaggaat atagattcct ggttcaagag
    22441 agaagcacat cccttcttca atcactaagt cgtttccttc tacaagagaa gggaattcgt
    22501 ggacggttgt tccgattccg tgacctaaac ggtgattgaa atattcgccg tagccatagc
    22561 tgttgatcac gtttcgtgcg atttgatcaa gttcacctgc tgtcacacct gggcgaactg
    22621 cctcttgtgc ggcaagctgt gcttcaagag tgatgttata gattttttct tggaattcag
    22681 ttggtttttg ataagcaact gtacgagtag catcactgca atagccattc caaataacgc
    22741 caagatcgaa taacactagt tcatttggtg aaaccttcgt gcttcctggt gtaccatgag
    22801 ggcttgcagc atttgctcct gcaaggacta atgtgtcgaa agacatttgt gaaacacctt
    22861 gtttttttaa ttggtattcg atttctgcga taattgcttg ttcagttacg ccttctttta
    22921 ctgttttgaa gccaatttca aaggcaacat cggcccattt accagcttcg atcagtttgt
    22981 ctttttcttc taccgttttg atcagttgca gacgctggat aatagaagtt agatcggtgt
    23041 aagaatctgt acctgtcaag atatcagaga tagcatcgaa gcgatcgaca gtcagagcat
    23101 tcttttcaat acctacatta ccaggttgcc catagcgtgc gcgaagctct tttccgatga
    23161 tctcccaagg attttcgctg tctaagtagc cacgtacatc gtacgcccag ctgctgtttt
    23221 gagcatcttc aacttccaga gcaggagtga aaaggaaagg atcttgttcc agagggataa
    23281 aaagagctag tacacgctcg tgaggatcac tttcatatcc ggaaaagtaa gcgatgtggc
    23341 cagggtcgct gatataagcc aattctaatt ggtgttgtgc catccattga cgtagttcat
    23401 tgatttttac gttattcatt tggcaaccta ctttctaaat taattttgta ttcaataatt
    23461 gtaccactga ttgattaaaa gaccaacgtt cttaaaactg aaaaaagtaa aaattttcat
    23521 gaaaacagag ataaaacggt tgcaattgtt gagattattt gatatcctat tttagaaatg
    23581 taagacgtat tttcagaaaa catataaaat atgaatagga gaacacaaat ggaaaagcaa
    23641 acaatcacta tctatgatgt agcgagagag gcaaatgttt cgatggctac tgtttcacgt
    23701 gtcgtaaatg gcaatccaaa cgtcaaacca gcaacaagaa aaaaagtctt ggaagttatc
    23761 gatcgcttgg attatcgtcc aaatgcagtc gcacgtggct tggcaagtaa gaaaacaaca
    23821 acagttgggg taatcattcc tgatgtcagc aatatgttct ttgcctcttt agcacgtggt
    23881 atcgacgatg tggcaacaat gtacaaatac aatatcatct tagcaaactc agatggcaac
    23941 gatcaaaaag aagtcaatgt attgaataat ttattggcta agcaagtgga cggcgtgatc
    24001 tttatgggtc accatatcac agacgaaatc cgtggagaat tttcacgttc aaaaacgcct
    24061 gttgtactag ctggttccat tgatccagat gaacaagtag gtagcgtaaa cattgattat
    24121 gtatcagcaa caaaagatgc agtaaataaa ttagcaaaaa gcggcaataa aaaaatcgct
    24181 tttgtcagcg gtgcgctgat tgatcctatc aatggtcaaa accgtctaaa aggctataaa
    24241 gaagcattaa gcgaaaacaa tctaccatat agcgaaggat tgatttttga ggcacaatac
    24301 aactttaaag atggtctgtc tctagttgac cggatccata atagcggtgc aacagctgtc
    24361 tatgtttcag acgatgaatt agccattggt atcttggatg gtttattaga ccgcggcgta
    24421 aaagtaccag aagaattcga aatcatcaca agcaacaatt ctttactgac agaagtagct
    24481 cgtcctcgtt tgacaagtat cacacaacca ttatacgatt taggagcggt atccatgcgc
    24541 ctattgacga aaatgatgaa taaagaagaa gtcgaagaaa aaacgattat cttgccttat
    24601 ggaatcgaag aaaaaggatc aactaaataa taaaagatca atcatttaaa ggttgttccc
    24661 aaagtggtca acttctggaa caacctttat acgagaaaag gggttatgac aaaattttgt
    24721 cataacccct ttttttgtga ctttaaaaaa aagagagaat ggcggaaaca aaccttacgt
    24781 ccatcgtata cgacacaatc tgtgcgtaga tgctacattt tgttcactac tatcaaaatt
    24841 actttaaaat gaaaacgtga taaaaaagaa agtagaaaag tagaaaagta actctaaaaa
    24901 atccaaaaaa atccaggctc gattgcgtac ttatcttaaa ggagaaacaa tccatcatac
    24961 ataacccgaa aggagacttc tatttgccta agaaaagacg aaagaccata gtcatcattt
    25021 tgaccattct tactatagga atcggaggaa aattttacat ggacaaaaga gaagcgcaaa
    25081 aacagcaaga tttactcgca gtagaaaaac agtccgtcaa agttctgaaa aatacctttg
    25141 cggatatcaa agaagtgaaa atcgaacaat ttgagaaaaa cgacatgaca ggaatctatg
    25201 aagcattgat aacgatgacc aatacagaag gaaaagccgt ttattttgat tatagcttta
    25261 caaaagaaag caatgagata gatggctatg gtgttgaaaa tgaagaagta caaaaagaag
    25321 ggattacggt tgatgagatt atagttatct atacagatgg gagtgaggaa aaagtatgac
    25381 aattactgat aagcagtata aaggaataag taataaagta tattggctag atccaaaaca
    25441 tcctcaatat agtaaaagtt acaaagaagg cgccattaaa aactttggag aaacaaaatt
    25501 ccaaatccta aaaatcaaaa actccttcga cggcatgcag gcgatggctg tagcgccaat
    25561 caagaacggt aaagtggata tttctcaagt agtgattgct tttgcaggaa cgaacttaag
    25621 cgattggaaa gatttggaaa cggatgcaag aagtgttatg aatctctatg ggaatagacc
    25681 aggagcaagt ttttctgaaa aagcaacaac aaacaagatt ttatccgtta gtggattgaa
    25741 aacagcgggg caaatcaatt cagcgattgc atttgctaat gaagtaaaaa aggaatatgg
    25801 agaagctgct atttctacta ccggccattc attaggtgga ttcttagcat tatatgtagc
    25861 agcagagaaa caatggaaaa atgtcggctt caacgggccg gacccgtatg atctcttatc
    25921 accagaagca aaaaaatggg tggaagaaaa tcccggtatg ctcaccaatt accgaaatca
    25981 cgccgatttt atcggtaatt ttggtggtaa tggcacaggt gctgaagttc ggatcagtat
    26041 ggaaacagca tacttgaatc tgcttgcttc ccacagttta acctcttgga agtttgatga
    26101 aaatggaaag ctgattattc ctgaaaatga aaacaatgtt aaagctcgaa aacaacagaa
    26161 agaaaaccaa gcgacccagt tgttttccta tcagttgcaa gaactgaaca acatacgtaa
    26221 aaaactacga ttaagtggcg gccggctgac agttaatgaa caaatttact tagatgacac
    26281 acaagctagg ttagtggtgg aaaagttatc ggtaaaaatg aaaagcgcta tggaagaagt
    26341 tatccgcatc aaccaaagag gaatttttga gctagagaaa aaatggcaag aaggcttgcg
    26401 gcaagcacgt gttgtcgccc cttcgttgac tgaacaggaa atcatagaag cattagctag
    26461 tgtgggcgcc acaaaagaga acttagtcga ttctgcgaaa gaagtctatc tgctacgaat
    26521 caataaggca agacgtatgg gggaggcctt tgatacattg gcgaaggaga tccaagacaa
    26581 aatcaatgaa atcgtggcac gagatcgaga attagcacag caattcaatt aaaggagaag
    26641 tagatgaaac tagaagaatt ggaaagagat tatcgaagtg aacgaagaca attagaagct
    26701 caagaagatg aattgatcca ctttaagaat caaggattac gattgatgga gcaagaggag
    26761 cagcgactgc atcatgtatt aaagaactta gctttagata atgagcctct gtttcaagca
    26821 agacgaagtt attcgaatta tcaggagcat tatcaacaag ccctacaagt agaacgacga
    26881 aaactctatc agcagcaaga cgaactagaa cgttcctatc gtcaaaaaat cagacaaata
    26941 actatggaga aatcatctta tgaatgaatt tttaatgcaa ttactaaaag aattagagaa
    27001 aaatctacat cgatcaaatg tacgttcagt tggtatgggg atatctcagc aaacttgggc
    27061 agaaaaacga ttgacagatc aaaaccacca aatgactgca gaagaagcta ctcaagaatt
    27121 ttctaaccga catgcacact taaaagaatc agtaaaaggg caatttgcag aaaaactaac
    27181 cgaattattc caaagacaag aaaagaaatt aaaacagttt cgttagtaaa gttatataga
    27241 aaaattttgt gaaaatggtt tttcacattt ttacataaat ttgtcttaat atcgtagatg
    27301 taagcttttg aacaccattt attcggaaaa agggagctgt gacaagattt ttgtcgcagc
    27361 tccctttaat tctgattaat ctattagatc aatcatcttt atcgtctgat tctttggtct
    27421 ctggattcgc tctagcataa gctgaagcgg tgttccagta atctgtatag ttttcatcag
    27481 taccgccaac gccgaattta aaggcgcttt tcttcggacc attttttgcc caaagtgatt
    27541 ccactgtttt tcctggcgtt tggatagatt ttttattgac agtaactttt ccagctgttt
    27601 gtcctgtgaa cccagatact tttttcttca tcacatcgga tgataagtca aatttctcat
    27661 cagtgccgaa aatctcaggg tttgcttggt aagcttgatt gattagattg gcaagataat
    27721 tagccgaacg tattcttgct tggctgtcca ttccagtatt gtcatcgtgt cctgcccaac
    27781 tactgatagt gatagatgga gttgagacga tcagccatga atctcggtat tcattggtag
    27841 aaccagtttt tccgacccaa tctgcatttc ctagatttcc gtttaagctt gagatgacat
    27901 ctttgaatgg tgtagtgatt ttttcattga tcacactacg catcatgtca ttcatgatcg
    27961 atgccgttgc ttcggaataa atacggacag aattactttc atgtttataa atcacattac
    28021 ctgcattatc tgtgatggaa tcaatgatat agccttcttc gtagactcca ccatttgcta
    28081 aggcctggaa tccatttgtc tgttgaagcg tcgttacatc tactgtccct aaaggagccg
    28141 attcaacgcc ccaattatca tttgctgggt agttcatctt cgccaagtag tgctcgtaag
    28201 cgtattgttt cgatccaccg gaattcaaca catcttgata taagtgataa gctgggatat
    28261 tgttggacca ttccagtgac tcacggacgg tttggaaggt gttcgaccct tcattggtcg
    28321 cattgacgat tttctcacca gcattttttc cttcttgcca agtcgttgca taatctgata
    28381 cacgggattc tgatccgaca agtcccatat cgattgcagg accgtaaaca agaaccggtt
    28441 tgatggatga accagcttga cgttctgtat caaaggcgtg gttattttga ttctggctgt
    28501 aattccgacc acccacgaag ccatagatac gtccggttct gttatccatc aatacatttc
    28561 cagtctccac ttggctacca gcaccatcat ctaacatgta gccataattt tctacgccgg
    28621 tttgcaatgc agcatagata tctttatcaa tcgtcgaatg gatcgtatat cctttgtttt
    28681 ggatcgtttg ctgtgctttt tgataataag cttcactgac cgatgaatct gacatatcag
    28741 cattatcttt ttctgccaat tgttgtgcaa taatccttgt tgcttcgttc atcacggtat
    28801 aatacaagaa ttctctgtca gtctgttccg cgatttgttg tgggagaaag tcttttgtaa
    28861 gatcataggc tttcgcttct tcgtattgtt ctttcgtaat ttgtccttca cggtacatac
    28921 tgaataaaac aaaatctttt ctggcaagac cggcagaaag atcttctttt agcgcgcctg
    28981 tattcgtgta tggactatac gtgatagggc tttgaggcaa accagcgata taagcagctt
    29041 gcggcagagt cacatccttt gcatctacac caaagattcc tctagcagct tcctggactc
    29101 cagcaatatt ttgcccctta ttattccgac caaatggtga gacattcaaa tacgtagtaa
    29161 tgatctcatc ttttgaaaag tgtttttcta cttgtgcaga aagaacgatc tcgtttgctt
    29221 tacgtttgaa tgttgtttca tcggttagga tctgttgttt gactaattgc tgtgtcaaag
    29281 tggatcctcc agacgagccg atgccagtcg cttctgaaac tagtgctcgt aaaacagctt
    29341 tagggacata accttggtgt ttatcgaagt attcatcttc tgtactgata atcgcggttt
    29401 tcaataaagg cgaaatctta tcagatgaaa tagtcgtccg catcagatct gtctggattt
    29461 ttgatatctc tgtattatct gcataaacaa tctttgacgt ttccgtaatg tttcctagtt
    29521 ctgtctgcag ttctttttta gtcggcaatt gtgtgtcttc gacaagatag gcaaagtagc
    29581 cagcacctat tccgatacct agagctgcga acaacaaaag aagaacagta ataaaaacag
    29641 tcaatgattg aaacactcta aaaataatct taggaacaaa ccatttttct ttttttcttc
    29701 tattctgttt ttttcgagta tttttgcgtg gcaaaagggt cacctcaact aatggtttta
    29761 tttcgctaat tatagcaaat aataggacaa aaaaacagac aaggctgttt ttgacaggaa
    29821 tttctttttc gaatgagata aaacgtgagg aaatgatctt ttttatgaaa gagttcttaa
    29881 gcttttcttt agggaaagtt tcagttacta tggagaacag ggcaaagaaa aacaaactat
    29941 tttctttgta catcatctta tcaatataca ggaattgttc gaaacaattg cctttcaagg
    30001 aggaatccat ccatgttatt aggctcacac gtcagcatga gcggaaagaa aatgctgtta
    30061 ggcgcggcag aagaagcagc cagttacgga tcttcgacct ttatgatcta tacaggcgct
    30121 cctcaaaata ctagaagaaa agctatcgaa gagatgaata ttgatgccgg aaaagcattt
    30181 atggcagaaa acggactaac aaatatcgtc gttcatgcgc cttatatcat taatttggga
    30241 aatacgatca aaccagaaat gtttccattt gctgtacaat ttctgagaga agagattgtc
    30301 cgtgcggaag ctttaggtgc tactcaaatc acccttcacc caggcgctca tgtaggagca
    30361 ggggcagaag ctgggattgc tagaattatt gaggggttga atgaagtttt gacaaaagaa
    30421 cagacggcac agatcgcttt ggagacgatg gcagggaaag gtacggaaat cggtcgaaca
    30481 tttgaggaat tagcgcaaat catcgatgga gtaaaattga atgaaaaatt atccgttact
    30541 tttgatacat gtcatacgaa tgatgccgga tataatataa aagaagattt ttcaggtgta
    30601 atggaagagt ttgataaggt catcggatta gatcggctta aagtactgca tatcaatgat
    30661 tctaaaaatc ctcaaggttc tcataaagat cggcatgcca atatcggttt tggaacaatt
    30721 ggatttgaca cattgaacaa aatcgtccat gatccaatgt ttgacaacat ttcgaaaata
    30781 ttagaaaccc catatgtcgg taaagataaa aagaaagctt acgcaccata tggaaaagaa
    30841 atttccatgt tcaaagcgca agcattcgat cccgaagtgt tccctgagtt attagcagaa
    30901 gaagtcacac tttaagtttt ctacctgaca gcaacaaaaa aggattgggc agtctgcctt
    30961 gtcctttttt gtttaagaaa caaaggagtg ctttttgcat tcgttttcgc catgctcctt
    31021 ttgccccctc tttttaaatt cagacaaaca gggtatactg atagaaaagt aaaaaacgaa
    31081 aagtttcaca aacaagtagc aaaacgtgat tgaaaggacg aaaagatgct gaacatttta
    31141 aaccccttga tcgaccaact aaaaaagaaa catacatact ttattcttgg catagccgta
    31201 ttatttacaa ttattcggtt gtatttatat agtaaagcaa tctatggaac agatatgtcg
    31261 gcgacctatg atgatcagct gctgattcac tatgctcaaa atattttgga tggtaaatgg
    31321 ctaggggagt acacgactac gacactttca aaagggattt cctacagctt gtttttagta
    31381 cttgcacata aactgcatct ttcttatgca gttttattcg gcatgttcag tattcttgcc
    31441 agtatattgg ttgcactagc gtttaaacca atcgtgaaga acaagtatct tcttttaagt
    31501 atctattttt attttttgtt ttctccgatt agttttacac atgaatattc cactcgaaca
    31561 tatcgtaatg ctctcgtgat cccgactgtt gagatcatta tcgcttgttt actagctatt
    31621 tattaccgca aatataattc cagcaaaaaa ttgctgccgt ggtttttagg gctagctgtt
    31681 tcttttcctt tcttttggtt cattcgcgaa gattccatct ggcttcttcc ttttactgta
    31741 gtcgcgttag gcatcagttt cgttcagatc ttgctaggac aagacttttc tttcaaagaa
    31801 gcaaagaagt taaaagaacg accatttctc ctttcgaaac aagaatggct gaaactttca
    31861 ttgtttttac tccctctagt cggtttctcc atcgtctatc agtggatcga atataaaaac
    31921 gagacaacat atggtattgc agccatcaat gaccgttcga gtggcgaatt tggacgtttg
    31981 atgaaacagc tgatccgaat agatgacgaa acaaacttaa ataaagaaaa cagtgagata
    32041 tgggtctcgc atgctgcatt aaataaagct ttagacgcat ctcctacatt tcatactgtt
    32101 tctactcgta ttgacgaatt gtatacgact catgcgtgga cccaaggcgg aaaagtaaaa
    32161 gaattaccag gagatatcat tttttgggca ttgcgagatg tggtaagcga atctggttat
    32221 taccaaaaca atgcaaaaga aaccaatgat ttttggaaaa aagtcaatca agaattagaa
    32281 gaagcctatc aaaagggaac tatcaaaaag aaaaaagaat tctatctgat gggatcaggg
    32341 gatggaaaga cgatgaatga tctgccaatc gtatttgatt ttctgaaatc aggatatgct
    32401 tatgcatggc gatacaaaga tttccatcaa ggggggaatt atagttttgg gacgcaagaa
    32461 caagtcgaac aggcacaaga attattgaat cttccactaa tggataattg gatcgatagc
    32521 agtgatccga gaacacctga tttccagttg acaaaaacag caaaagtcgc gaatgtcatg
    32581 ataaaaattt accaagttct ggccattccc gtgctgattg cttcaatagc agggatatta
    32641 cttatgatac taggaaccgt atttgcaaaa gctgatcgtg cctattatag ttcctctttg
    32701 attgtagtca tcggattaat actgacacaa ttggtttttc ttttcggtgt ctcgtggttt
    32761 tgttcttatg cgccagaaaa aaaggattat tttttaagtg tctacactgg cgcaggcgtg
    32821 ccattaacgc aattcatcgc agtaacaagc atgctagttt ttagtaaatt gaatctgaaa
    32881 aaagctttat cttccaaata aaaagggaac tgtgacaaaa gtcttgtcgc agttcctttt
    32941 tccgaataaa cggtgctcaa aagcttgcat ctgcggtaat aagctcaacc aaacgtaaaa
    33001 tatgaggaac tatttttgtt tggctgttct tattacttga tgcagggcag ctttttcaca
    33061 acctctgata cacggtgttc cagaagtaac ttcttcggaa ataagccgaa atttcacaaa
    33121 aatttgaaaa gcaattttct taaattcctt cttatttctt gaagctgccc acttctgtca
    33181 caacctcctt tgtgtaaaag aatcagtttc tattcgattt cttctatcgt ttcttgcaaa
    33241 cgctgttcat attttttgtt tcctttatat aaatcaccaa tcgtccatgc caacaggaga
    33301 aggacaagaa caatgattac ataggcgatt tgatcagcca atgctagttg agctgaggtg
    33361 gcttgctcgc cgaagaaact ttcgatttga cctggtaatc ctcgtaagtt caagtaagtc
    33421 agactaatca cagagaacca gccaagaagt tttacaacaa atgaattttt gaatcggctc
    33481 cccatctccg cttggctatt ggtcatcatc agtaaaggaa tcatcgagaa tggcaatgca
    33541 aaagccagaa aaacttggga ttcattcatc aagttattca aagcggtatg ttcttcgatc
    33601 gttccttttg tacttgtaaa caaaacacaa atcaatacag gaatcacaga aagcaatcgt
    33661 gtgactagtc ttcttagcca aatcgggata cgcatatgga tgaatccttc catgatgact
    33721 tgaccggtca acgtaccagt aatagtagag ttctggccag aagcaagaag tgctacagca
    33781 aataaagtag acaagatacc agattttgct acagcaatca agataccatt gctcatagct
    33841 gatggatcag ataaagcttc atacagacca aaaaaggaag gatcttggac agaaccggtt
    33901 ttgaatacag cgacacccat gatcaatagc agtgcattga ctaaaaaagc cattgacaac
    33961 tggatattag agtcccaagt agaaaagcgt accgcttgtg ctacatcttc ttcgtcttgg
    34021 tgatcgatct tccgagtttg agaaactgct gaatgaagat ataagttatg cggcatgact
    34081 gttgcaccaa taatccctaa cgctccagtc agcggagttt caccacctat gacaggtgag
    34141 tctgagaatg tatgactgtt agggataaag ccagcaaata aactgtgcca atcagggtta
    34201 gacaagccaa cttgatagac gaaaacgaat aaaatgacga aaatcaagca gacaaccaaa
    34261 gcttcgattt tacgaaaccc gacttttgtc agcaataaaa ggacgaaaac atctaacaca
    34321 gtgataaata cggcaattac caatggaata tcaaaaagta agtagagggc gattgctgca
    34381 ccaatgactt ctgcgatgtc tgttgccata atggctaatt cagtcaagat ccataaaatg
    34441 acacccaatg tcttacttgt ccgtgctcgg attgcttggg ccaaatccat ttgggtcacg
    34501 attcctaatt ttgctgccat atactgtaaa agcatagcaa ttagactaga catcaaaata
    34561 actgacatca ataaatattg gaaattttgt ccaccagtga tcgaagtgga ccagttacct
    34621 ggatccatat aaccaactgc tactaatgca cctggtccag agtaagcaag aagtgtttta
    34681 aaaaaacttt ttccctttgg tacatccact gttccattta cttcagctaa agataaacca
    34741 tttgtatgtt caataagtcg atgcttatga aattgtttgt tggattgatt attcaagaaa
    34801 aaaccacctt tcctatttat ctacgattac attctacacc tcagaaagaa aaaattaaag
    34861 aaaaagattc ggtatgccta attttttttc gtggcgtgtc ttgctggtta atgaaagaaa
    34921 ttttgttctt ctctaaaaaa accactattt tttgcatgaa actaaagaat acgcctttct
    34981 tttttcaata aactttagta aaataaatca ttgagagcaa ttcggaaata gaaaggagag
    35041 atttatatgg tatcaacagg tattgtcgta cttattgcta ttattgcttt gctaatcggc
    35101 gcagtaggtg gctttttcct agcgcgtaaa tatatgaaag actatttaga aaaaaatcct
    35161 cccgttaatg aggacatgtt gcgatcaatg atgatgtcaa tggggcaaaa accatctgag
    35221 aagaaaattc gccagatgat gcagcaaatg aagaaccaag ggaaaaaata ggttctgacc
    35281 caaagacttt ttgcgggctg attttttcag tccgtttttt atttcgtaat ttgttagact
    35341 attcagacta ttcagcaaaa aagacaagga cagacaatcc tatgctcttg ataaagacaa
    35401 aggaggagta aaatgtcgat ttttagaaaa ttaggttggt tttttcgtca ggaaaagaaa
    35461 cattatttaa ttgggatttt ctccctattc gcagtggcct tggtacagtt agttcctcca
    35521 aaagtgattg ggatcatcat tgatgagatc gccgataaga atttatcaat aaagatcatt
    35581 tcttggtgga tcttactatt gatccttgca gctttcttac aatatctttt tcgttatatc
    35641 tggcggacga atatttgggg aagtgcagct cggttggaga aagaacttcg gcagcagcta
    35701 ttcaaacatt ttacagaaat ggacaatctc ttttaccaaa aatatcggac tggagatttg
    35761 atggctcatg caacgaatga tttgaatgca atccagaatg tagcaggagc tggaatcttg
    35821 acctttgcag attcagtgat tacgggcgga acaacgatca ttgcgatgat tttgtttatt
    35881 gattggcgct taacactgat tgcgctgatt cctctgcctt tgctagccgt tacttcacga
    35941 gtgctggggt caaaactcca cgatgctttt cgtgattcgc aagaagcttt ttctagtatc
    36001 aatgataaga cacaagaaag tatcactggg atcaaagtca ttaaaacatt tggacaagaa
    36061 aaagaagatc tcgcggattt tgaagaaaag attgaagatg caattattaa aaacaaacga
    36121 gtcaattttt tagactcctt atttgatcca ttcattacct tgattatcgg tctgtcttat
    36181 gttgcaacaa ttattttagg tggaaagtat gtcttggaag gcacgatctc gattgggcag
    36241 atggtctcat ttattagtta tatcggtatg cttgtttggc cgatgtttgc gattggccga
    36301 ttgttcaacg tattggaaag aggaaatgct tcttatgatc gcgttaatga acttttgcat
    36361 gaaaagacgc atatcgtgga acaactgggt gcagtgcaga ccccggcaaa aggcgagctg
    36421 aatgtagcta tttcctcttt taactatccg aaagaagaat caccagcatt agaacaaatc
    36481 aaatttgcga tccaagaagg agaaacatta ggtattgttg ggaaaactgg tgcgggaaaa
    36541 acgacaatca tcaaattact gatgcgtgaa tacgatgatt atcaagggaa aatccaattt
    36601 ggcggacgtt cgatcaaaga atattcattg aatgctttat taggatcaat cggttatgtg
    36661 cctcaggatc acttcctgtt ttcgatgacc attcgagata atatccgttt ttctaatcca
    36721 aaactttcag aagaagaagt agagcatgcg gcttctttag catttatcaa caatgaaatc
    36781 aaggaattgc caaaaggtta tgatacctta gttggagaac gtggagtctc tttatctggc
    36841 ggacagaaac aaaggatttc gattgctcga gcattgatca aaaatcctga attgctgatc
    36901 ttagatgatg cactttctgc agtagatgcc aaaacagaag aagctatctt gcataattta
    36961 aaagaaataa gaaaagagaa aacaaccatc attgcagctc accgtttaag cagcgtgatg
    37021 catgcaaaag aaatcattgt tgtcgatcaa gggaaaatca ttgaacgagg aacccaccac
    37081 gagctgcttg cattaggtgg ctggtatgaa cgaatgtggg aaaaacagca attagaagcg
    37141 aagatagaag gaggcgaggc ctgatggatg aaaattatca atcggaatgg acaaaatcga
    37201 ttccacttaa agaacagaag aagatcatca aacgactgat gaagttcgcc aaacctttta
    37261 gaagaacgtt catcgttgct atcttatttg cgtttgccct gtctgtgatc aatgtcctat
    37321 tgccaaggat catccaaact tttatggatg atcatctggc taaacagtca gctacgacac
    37381 aagttatttt gttttttgct ggtgtgtact tgtttggagt catagtcaaa agtatcattt
    37441 ggtttttcca atggtatttg tattccatgg cttcattgaa gacctatcag tatgttcggg
    37501 taagattatt tgaaaagctg catacactag gtatgcgtta ttttgaccag acaccggcag
    37561 gatcgaccgt ttctcgagtg acgaatgaca cagaaacgct atttgaattt tggtatgtct
    37621 ttttgatggt attgactggg atctttgcag tcgtttcttc tttcgttgcc atgtttcaaa
    37681 tcaatggaga aattgccttg tggactttgg tgttcttgcc gattttagga atcgtcatct
    37741 ggtattacca gaaattcagt tctcgtattt accgaaatat gcgggaaaaa ttaagtcagc
    37801 tgaacacgaa attgaatgaa tcgatttccg gcatgcgtat tatccagcag tttcgccaag
    37861 aagctcgttt agctaaagaa tttgaacaag tgaacaacga gtatttagac acgcgctatg
    37921 cgatgatcaa aacgaattcg attctgttaa gtccgatcat caattttctc tatgcattgg
    37981 cgattgcgtt ggcgttgact ttgtttggga tcgatgcgtt gcattctccc gtagaagttg
    38041 gactgatcta tgcatttacg acctatgtcc agggattttt taatccaatg tctcaaatga
    38101 tggacttttt gagcaccttt acagatggga tggttgccgg tagtcgtatt ttgaaaatca
    38161 tggatacaga agaatatgca ccgcaacaaa atcctggagc agatcaagcg attacttcag
    38221 gtaagatcga gtttcgcaat gtaagctttt cttatgatgg agagcacaat gtattgaaca
    38281 atatctcttt tgtcgctaat ccgggtgaga ccgttgcatt agtggggcac accggaagcg
    38341 gaaaaagctc gatcatcaac gtattgatgc ggttttacga attttatgaa ggccaaatct
    38401 tgattgatga tcatgacatt cgagaatatc caatggaaga gttacgtaag aaaatgggat
    38461 tggtcttgca agatgccttc ttgttttatg gagatattgc aggaaatatc cggatgatga
    38521 atccagctat cacagacgaa cagattcgcc atgcagctga gtttgttcaa gcaaacaagt
    38581 tcatcgatga attaccaaaa ggatatcact caaaagtgat cgaacacggt gccagctatt
    38641 ctagtggaca acgacagctg atcacttttg cgcgaacaat cgtgacagat cctaaaatac
    38701 tagtattgga tgaagcaaca gcaaatatcg atactgaaac cgaaggattg atccaagaag
    38761 gattggcaaa aatgcgacaa ggacggacaa cgattgcgat tgcccatcgg ctgtccacga
    38821 ttcgggatgc agaattgatt ttagttttag acaaaggtca tatagtagag cgtgggaatc
    38881 atgaaacact tctagcgcaa aatggtttgt atgcagatat gtacaaactg caaagcagtg
    38941 gtgtgtaaaa agaggttgtg acagtagcat agtagcattt tgtcctaagc gctagagtga
    39001 aaataaaaca gagcttccca gattcttcat ctgtgagcgt tagtggcgta gtcacccgat
    39061 ttaaaaaaga cgacgacagc tagtcaaaag tgcctaatag ccactaagaa agcgttgaca
    39121 aaagcgtttg ctttcgataa tataaagaaa acgatacaac ttggatagtg attgcctgat
    39181 gcaagctaaa cctgatgagt ctcccatggt tccatggacg gctttttggg tttttctttt
    39241 tgttttgaat acagccctat atatcatgga aaggagcaaa acatgctgat tgagaaagta
    39301 ctgaataaca acgtcgtaat aaccagggat gaaagaaatc aggaaatgat cgtgatggga
    39361 aaaggtttgg cattcaaaaa gaaagtgggt gacccgattt ttgactcatg catcgacaaa
    39421 aaatttcagt tgacaaatga cgggctttca caacagttcc aagaattggc acaagcgatt
    39481 cctcttgagt acttagaaat ttcttgtgaa atcattgaat atacaaaaga ggctctacaa
    39541 gtccagttga atgattctgt gtatattgca ttgacggatc atttgtatac ggctatcgaa
    39601 cgtcacaaaa tgggaatatt tgtaccaaat gtattgctgt atgatatcaa acaactattt
    39661 cctaaagagt atgccatcgg gaaaaaaaca gtgaagaaaa tctcggataa ataccacatc
    39721 aagttatcag aagatgaagc cggatttatc gcattgcatt tagtcaatgc acaaggcatt
    39781 caaagccaac aaaacaatac ctacctgttt actataacaa tacaggatat tctaaatatc
    39841 gtccgctatt actataagat tacatttgat gaagattcag tccatttttt tcgattcgtc
    39901 acacacttac gtttttttct gacacgcgtc ctagatggag aaaaatcaga agtgggagaa
    39961 gtttctgagg aattgtttca ggttattcaa aaaaaatata aggatacgtt tggttgcgtt
    40021 gagaaaatag cagacttttt agccgagacg ttcaactacc agatgtccac ggacgaaaaa
    40081 atgtatttaa cgatccatac tgcgcgttta gtgcatgaga atcgttgtaa ataaataaaa
    40141 aaaggaggat aaattaacaa gaacgtatga aataagggta gtgacattca gttggctaaa
    40201 ccttccacta atatattgga gggaatagaa atgggaaaat accaagaatt agcgagaaaa
    40261 atcgtagaaa atgtcggtgg gaaggaaaat atcaatggtt tgacacattg tatcacaagg
    40321 cttcgtttca aattaaaaaa cgaagaaaaa gcaaatgatg agatcttgaa aaatatggac
    40381 ggtattgtaa cggtaatgcg agcgggaggg cagtatcaag ttgtcatcgg gaatcatgtg
    40441 ccagtcgtgt ttgaagaggt tataaaagca ggaaacctta cttttgatga ggctgtttca
    40501 acagaaaaaa tgagaccgtt tgatatgctt attgatggaa tatcgggctg tttccaacca
    40561 ttccttgcta tcttagctgc tggcgggatg attcgtggac tgacagcatt ccttgtcttc
    40621 ttaggcgcgt ttgaccgcgg ttctggcaca tttgttatgt ttgataatat cggtgattct
    40681 gtattccaat ttatgcctgt tattatcggt ttaacagctg cccgtaaatt taaagtaaat
    40741 gaattcgtag ggatgttgct tggcgcagca ttaatgaatc ctagcttgtc gctggaagct
    40801 ttgagtggtg cagcagaagc accactaacg accatatttt ctggcactat ttttgaagca
    40861 cctatttatc aaacagtatt cggcattccc tggattgcgc gtaactacgc ttcttctgtc
    40921 attcccatta tctttattgt gttgttagct agccaaattc agaaaccaat taaaaagtta
    40981 gtacctgaga tgatcgcgaa tttcttcgtt ccattcttca ccgttcttat tacaatgcct
    41041 ttaggttttt tactcgttgg accagtattc acattcgcaa ctgatatttt aatggctgga
    41101 tttgaaacac ttttagcact ttcgccagtt atttatggag caatcgtagg cttcttctgg
    41161 caaattctgg tgatgtttgg tctccattgg gcaatcgtac caatgggatt gatgcaattt
    41221 tctgtgaatg gttggcaaaa tattatgaca cctgttgcag tagtgtcttt tggacaaact
    41281 gcagcactta ccgcactcta ctttaagctt agaaatccaa aagacaaagc aattgcaata
    41341 ccagccattg tttctggtat tgtggggatt acagagccag ctatttatgg gtttacatta
    41401 ccacgtaaaa aaatatttat ttttacttgt gtcggtggtg cgttaggggg cgcgtatagt
    41461 gggttaatga atttaacttc ttggaatcaa ggtggactag gcatctttac aattcccaac
    41521 tatattagac cagatggtga tttaacagat gtgattaatg tattgattgg gatcgccatt
    41581 gcgatggtgg tatcctttgc gctgactttt ttcttttgga aggaggaagc aggtgaaaca
    41641 gatgacagac agaaaagatc aggtaaagaa attgtaaaaa caccgataca aggacaaatc
    41701 gctccactga aagcagcaaa ggatgcagct tttgcacaag gaacactagg tcgaggaatc
    41761 ttgatctacc ctgaaaaagg agaagtacgt gccccttttg acggaacagt catgaccctg
    41821 ttccccacga aacatgcaat cggaatggtt tctgaaacag gtctggaatt gctgattcat
    41881 gtcggattgg atactgttca gttggaaggg aaatattttg aaagcttggt gcagcaagga
    41941 gaaagagtga aacaaggcga tctgttgctc cgcttcgaca aaaagaaaat cgaaaaggaa
    42001 ggatacagtt tagaaacacc tgtaatcgtc accaattaca tggattattt ggatattttg
    42061 gaaaatcaag gggagacggt cgggccagac gatgcactta tcaccgcact gacctgaacg
    42121 gttaggtgaa agaatggaat agacttaact attcttttta gtccacttct ttattttcaa
    42181 aattgaaagg ctctttcatg atggctgagc tgatagggcg tttatcaaat ttttgtccta
    42241 cagaaattag atggactaaa ttctgttgat aattttctgc aaaaacacaa ctatataaca
    42301 cgtctagaag ataacaaatc gatgtattga tcgtaaaatt accaattttt gaatacagtc
    42361 gttcgcgtgt cgtaagtcgc aaagcggctg tactcattga ggatagcgtt gaatcaccga
    42421 tactggtcaa cgctaaaatt ggaacatgat tttgtttcaa tatttctgcg gtacgaagga
    42481 tcacattgtt ttcacccgta taagaaatca gaatcccgca catatcactc gtgcaattgt
    42541 acgcttcata gaacgattca ccaaaagtgg tgacaatcgt gacatccatt ttgatgcgct
    42601 tcattttcag catgaaatct tgagaaatca aagtattcga gttactggcg aaaatcacga
    42661 ttttttttgc ttgaagcatt agttgtttgg ctttttgcag ttggtcatga tgaatgagag
    42721 aaagtgtatc ttgaatcgtc atctgttcta aagaagccat tttatttgcg atcgtcataa
    42781 taccgtctgt ggtggaaaaa ggaagattcg catctacgtc ttgaaaattc ccttcaagat
    42841 aggctgtttc agctaaaaaa gcattacgaa aactgaccca gccatcaaaa cccatttttt
    42901 ttgctacacg gatgagtgtg gacgggtgga cataacatcg ctcagcaatc tcttggatgg
    42961 tcatttcgcc aagtgctgga gaatcgctta agagaaactg aatcacttca ttttctgaag
    43021 gagaaaagga gatttctttg attttttcac gtaataacat gtagatacct tcttctagtt
    43081 tttttacgta aattataact tttttgaaaa tgatttgtaa acggatttat gttatatagc
    43141 ttaataaagt cattttttga caagatattt acaaaaatcc agtagaaaac actaactttt
    43201 gtaaatgtta ctggaaagaa acgaatttct attgtttgtt ttgtttacaa aaaagataat
    43261 aaaagtgtaa aaagcaaagg agtgagaaca tggcaaaagg aatcaaaatc gctacgattg
    43321 gtggaggcag cagttacacc cccgagttga tggaaggatt tatcaaaaga tatgaggaat
    43381 taccgatacg agaaatctgg ctcgtagatg tagaagaagg aaaagaaaag cttgagatcg
    43441 tcagtcagat gtctcagcgt atgtgggatg cttctccgta tgaagtcaag atctatgcaa
    43501 ctttggatcg ggaagaagca ttgaaagatg cggattttgt tacgactcag tttcgtgtcg
    43561 gtcaattaga tgcacgaatc aaagacgagc ggatccctag ttattatggg atgattgggc
    43621 aagaaacaaa tggtgctggc gggatattca aagcttttcg taccgttcca gtggttttgg
    43681 caatcgttga agacatgaag cgtttatgtc caaatgcttg gctgatcaat ttcgcgaacc
    43741 caagcgggat ggtgacagaa gcagttatca gatatggcaa atgggataaa gtgatcggat
    43801 tatgcaatgt gccagtaatg gcgacgatga cagaaccagc aatgcttggc aagaaaaaag
    43861 aagagctgat ctacaagttt gccggtctaa atcacttcca ttggcacaaa gtagcagata
    43921 ataaaggaaa tgaccgcaca gcagatttga ttgatcgttt atacgatgaa gacaatggat
    43981 tgccgaaaaa tatctttgac atcccgtttt tcaaagaaca attaaaacaa atgaacatga
    44041 tcccttgtgg ctaccaccgc tattactacc gtgaagaaga aatgttggaa catgctttag
    44101 aagaatatca aacgattggt acaagagcgc aacaagtgaa agaaacagaa gcagagctgt
    44161 ttgaattata caaagatcca gaattggatc ataaacctga acaattgcaa aaacgaggtg
    44221 gtgcttatta ttcagatgct gcctgtgaaa cgattgcttc gatctatgga aataaagaaa
    44281 cacagatcgt ggtgtctaca aagaatgatg gagctgttcc tgatctgccg gcagattgtg
    44341 tagtagaagt cactgcctat gttggcgcac aaggcgcacg aaatgtagcg tttggttccc
    44401 ttcctgctgc tgaaagaggc tggttgcaag taatgaagaa tatggaattg ctgacgatcg
    44461 aagcagccgt gactggtgat tatggaacag ctttacaagc gtttacgatc aatccgctta
    44521 tacgatcagg aaagacagca aaacggatca tggatgagtt gtttattgca catcagcagt
    44581 atttaccgca attcaaggaa acaatcagcc ggttaaaagc agaaggaatc gaagtccaag
    44641 atgaactggc aagagaattg tcaagcaata cacatgtaat ggaggaagta tgatgggatt
    44701 cagaaaagat tttttatggg gcggtgctac agcagccaat caatgcgagg gtggttatga
    44761 tgaaggcgga cgtgggttag cgaacgtaga tgttgtgcca atcggagaag accgttttcc
    44821 tgtcattact ggaaaaaaga aaatgtttga atttgataaa gatcattttt atccagcaaa
    44881 aattgcgatc gatatgtatc atcattataa ggaagatatt gctttgtttg cagaaatggg
    44941 gttcaagact tatcggatgt ccattgcttg gagtcgtatt tttccaatgg gcgatgaaaa
    45001 tgagccaaat gaatctggtt tgaaatttta tgaggatgtc tttaaagaat gtcaaaagta
    45061 cgggatcgag ccgcttgtga cgattacaca ttttgattgt ccgatgcatt tgatcaaaga
    45121 atatggtgcg tggcgttcta gagaactcgt tggtttttat gaaaatctgt gccgagtcat
    45181 cttcaatcgc tataaaggac ttgtcaaata ttggttgaca ttcaatgaga tcaatatgat
    45241 ccttcatgca ccattcatgg gcgcagggct gtattttgaa gaaggagaaa atgaagaaca
    45301 aatcaaatat caagcggcac atcatgagtt ggttgcaagt gccatcgcaa cgaagattgc
    45361 tcatgaagta gatccggaga acaaagtagg ctgtatgctg gcagcaggag catattatcc
    45421 atacacttgc aatcctgaag atgtttgggc ttctagaaaa tcagatcgag aaaattattt
    45481 cttcattgat gtccagtcac gaggagaata tcccgcttat gcattgaaag aaatggaacg
    45541 aaatggcatt cagatcaaaa tggaacctgg ggatgccgca ttgctgaaag aacatactgt
    45601 tgattttatc tccttttctt attattcttc tcgagtttcg actactgaca acgaactctt
    45661 ggaacagact gcaggaaata tctttgcttc tgtcaaaaat ccatatctgg aagcaagtga
    45721 atggggttgg caaattgatc cattaggctt gagaataacg atgaatgata tttatgatcg
    45781 ttatcaaaaa ccactattta ttgtagaaaa cggcttaggt gcagtcgata cgcccgatga
    45841 gaatggttat gtggaagatg actatcgaat cgactatctg gcagcacata tccaggcaat
    45901 gaaagataca gtagaattag atggagtcga tctattaggc tatacgactt ggggatgtat
    45961 tgatttagta tcagctggta caggtgagat gaagaaaagg tacggattca tttatgtcga
    46021 tcgtgacaac gaaggaaatg gcacattagc ccgttcgaag aagaaatcat tcaactggta
    46081 taaaaaagta attgattcaa atggagaaaa tctttcgaat gattgatcaa tgatttgtaa
    46141 aagtctattg tttttcagcg gatttttcga gtataataaa gctattcgag aaacgcaagc
    46201 agaacaatag actttttttc gcattggctg taaagtatgc ttacttgatt aagtaaagga
    46261 gaatctacat atgtatgatg taatcgttat tggcgcaggt cctgctggga tgactgctgc
    46321 tttatatgct tcacgttcaa acttatccgt attgatgatc gaacaaggcg cccctggcgg
    46381 ccaaatgaac aatacggcag aaatcgaaaa ctatcctggt ttcgattcaa tcatgggtcc
    46441 tgatctagct tataagatgt atgaaggtgt ttcaagattt gggacagaaa atgcttatgg
    46501 aatcgtgcaa gatatcaagg atcacggcag ccacaaagaa gttatttgtg aagataaaac
    46561 ttacgaagga aaaacagtca ttatcgcaac aggctgtatc caccgtaaat taggcgtacc
    46621 tggcgaggaa gaatttgctg gacgtggcgt ttcttactgt gcagtttgtg atggtgcgtt
    46681 tttccgtaac aaacgtctag tagtgatcgg aggaggagac tcagcagtag aagaagccat
    46741 ctatttgaca caatttgctt ctgaagtagt catcgtccac cgtagagatg aattacgtgc
    46801 acaaaagatc atccaagacc gtgcatttgc gaatgaaaaa atttccttta tgtgggatac
    46861 agtcgttgac gaaatcgttg ggaatgaaat ggtagtgaca ggtgtgaaag cacgtaatgt
    46921 caaaaccggc aatgagtttg atttggcagc agacggagta ttcatctatg ttggactgga
    46981 tccattaact gcaccattta gagaagcagg gttgacgaac gaagctggct ggattccaac
    47041 agacaacgaa atgaagacga atataccagg cgtttttgcc atcggagatg ttcgtgaaaa
    47101 agatttgcga caaatcacta ctgctgttgg tgatggtggg atcgctggac aacaagtgta
    47161 taaatacttg gaatctttag aagaaacaac tgcataagtt taaaaagagt ggaagaacgg
    47221 tttcaattgt tcttttactc ttttttttcg cgtgaaatct actgaatccg atttatgcga
    47281 atacttgcaa ccgtgcttga taaaagaatc ctttcttgat ttaagcgttt tttagacctc
    47341 gtactttcat atctaataag tgaatgctat acttattaag aaccatattt cagaaagagg
    47401 tgttattttc atgtcttggg aacaagtgta tgaacaatgg gtacatgaag aaaatttaga
    47461 agaaaactta aaaaaacaat taattgatct gggtgaagat cctgaaaaac ttgaagatgc
    47521 tttttatgca ccgttggaat tcggtactgc aggcatgcgg ggaatcttag gacctgggat
    47581 caatcgaatg aacatctata cggtaagaca agcaacagaa ggacttgcac gtttcatgga
    47641 tacacaaggt gaagaaacaa aacgccgagg tgtcgctatc gcttatgact cacgccatca
    47701 atcaccagaa tttgccatgg aagcagccaa aacattagca catcacaata tcccttctta
    47761 tgtattcgaa agtttacgtc caacaccaga gctttctttt gcagtccgtc atttgaagac
    47821 gtttgcggga atcatggtaa ctgcatccca caatccagca gcttacaacg gatataaagt
    47881 ctacggagaa gatgggggac aaatgcctcc tgcagacgca gatgcattga cgaaatatgt
    47941 ccgtgaagtc agcaatccgt taaaagttga agtattatct gacgacgaag ctgaacatag
    48001 cggattgatc acgatcatcg gagaagaagt ggatgccgct tatctagaag aaatcaaagc
    48061 agtaacgatt gatcatgaat tggtggaaac aatgggtaaa gatttgaaac ttgtgtacac
    48121 accacttcac ggaacaggaa aaatgttggg cgaacgtgcg ttgaaacaag ctggattcga
    48181 acaattcgta ctagttccag aacaagctgt cgcagacccg gatttcacta cagtcaaatc
    48241 accgaatcca gaagaacact ctgctttcga gtatgcgatg cgacttggcg agaaagaagg
    48301 cgctgactta ctgattgcaa cagatcctga tgcagaccgt ttaggcgcag ccgttcgttt
    48361 gccaaatggc tcctatgaag tattgacagg gaaccaaatc ggagccctgt ttgctcaata
    48421 tattttggaa gcacaccaat cgcgaggcac tttacctgaa aatgcagcgg tattgaaatc
    48481 aatcgtttct agcgaattgc ctacagcaat tgcggaacac tatggggcta ccatgttcaa
    48541 tgtattgaca ggattcaaat tcatcgctga aaaaattcaa caatttgaag aagatcattc
    48601 ccatactttt atgttcggat tcgaagaaag ttacggttat ttagttaaac ctttcgttcg
    48661 cgacaaagac gcgattcaag cattgctctt attagcagaa gtagcagctt actataaaaa
    48721 acaaggcaaa acgttgtatg acggcttgca aacgattttt gaaacatatg gctactacgc
    48781 agaaaaaacg atttctgtga caatgagcgg acaagaaggt tctgcaaaaa tctctgcttt
    48841 gatggaaaaa ttccgtgaag aagcaccgac agaatttgcc ggagcaaaag tcatccaaac
    48901 agaagacttc aaagagttga cgagaacaga ccgtgaagga aacgtagaaa aactaacgac
    48961 accgccatct gacgtattga agtatacgct ggaagaaaat ggctggatcg ctatccgtcc
    49021 ttcaggaact gagccgaaaa tcaaatttta tatcggtgta aaaggaaact cttcagaaga
    49081 cgcagctgaa aaagtagccg cttatgaagc gattatcaaa aaaatgacag aagaataaaa
    49141 aaacttgaga ctgatggaaa aagtggtaaa ctttagaagt cagtcttttt tcaagttgga
    49201 ggtgaatgga ttgccagaca cgcaaaaaac aaaagtagag aaagtcagcc aactattcaa
    49261 aatgttgagt gaccccactc gtctcaaaat tctgctgtat ctgaaagacg gggaacaaaa
    49321 tgtgacagca atcacccaag cagtagaaat ggaacaatct gctgtatcgc atcaactgcg
    49381 tttattaaga gaaaaccatg tcgtcaagtc ccatcgtgag ggaaaagcga ttttgtatag
    49441 tcttgatgat tctcacgtac tggatatttt gaaccagacg ctcaaacatg tggaacatca
    49501 ataacgatag gtgcaaatag agacaaactg gactgtatca acgaatcttc ttcgctgaca
    49561 cagtccagtt tttttaagaa aaagacaaga aaaactgtta gtctgtttct tcggtggttt
    49621 cagttccata ataactatga tcttctaggt ctaaagcatt caaaataagt gaagctgttt
    49681 cttcgataga taaagaagcg acattgatta ctacgcagcc caatttttca taaagatcat
    49741 tcgcaaaatc gagttcagct cgtatttttt cgatatcgga ataagcagta tcaggattta
    49801 atccgtaaga gcgcatccgt tctttacgga tattgtttaa aatatctggg ttattcgtca
    49861 gtcccacgat ttttttagga tcgatctccc aaagctgttt gggaatatgt gcttgtggga
    49921 tcaaaggtag attggcaacc tttaaatttt tgttagctaa aaacaagctc aaaggcgttt
    49981 tggaagttct ggatacgcct agcaaaacga catctgcttc tagaaaccca cgaggatctt
    50041 tcccgtcatc gtattttaca gcaaattcca ttgctttgat ccgtttgaaa tagttctcat
    50101 tcaataaatg aagggcgcca ggttgccgaa tgggcttgat accagttaag cgctcgattt
    50161 ctgatatcgg cggagtcatc acatcaaaac taaataattg atgttcttca caaaaagaac
    50221 gcgtcatctc gatcaattct tgattgatca atgtgtgcag gacaagggct ttttctttta
    50281 gtgcatcttg cagtgcctgc atcaatgttt tctcatctgt cacaaatgtt ctgcggaata
    50341 aattgaactc aacggtagga tattgggcca tagtggcttg cgctaatttt gtcgcagttt
    50401 ctccagcaga gtcagagatg acaaaaaaag taacgatttc tgtagaatcg gaagacatgg
    50461 ataaaacctc acttgcattt tttttatgtt tattatacca tactctagaa tgtgtacttc
    50521 gtaatcattt tgatttggag gaataagtca tgaaaaaaca gacattgatt gaacaatcac
    50581 tagaaacatt gaaaaataac ggttttaaat atactaaaaa aagagaagca ttgttaactt
    50641 atttagtgaa gcgcaatcgc tacgtatccg ctaaagaagt ttttgactat atgaatcagg
    50701 aattcaaagg agtaagttac gatacgattt atcgaaatct ccatgatttt gcagaaatcg
    50761 atttactgga agaaaccgat ttaaatggag agatgaagtt tcgttttcat tgctgtcaag
    50821 gggaaatcgg ccatcaccat cactttatct gtacggtgtg cggaacaacg aaagaaatcc
    50881 atatgtgtcc aatgaattat ttcgaagaac agctcggtgg atgtacgatc gaagggcata
    50941 gattcgagat tttcggaaga tgtgaaaatt gtcaataagg atttaaataa aataacattt
    51001 gataatttta aaaaaaagca agatttcctt gacggtcaaa acagcattag atataatatt
    51061 tacaggacag tcttgttttt tgagatatat ttcaataaca attacggtta ctttttaagc
    51121 tcggagggag ggaattaaca tgtcaaaaac agtcgttcgc aaaaacgaat cacttgacga
    51181 tgctcttcgt cgcttcaaac gttccgtgtc aaaagcgggt actttacaag aatctcgtaa
    51241 acgtgaattc tacgaaaaac caagtgtaag acgcaagaaa aaatctgaag cagctagaaa
    51301 acgcaaaaaa ttctagttct gtgatgaatt ggagttggta gtgtgtcact actaagtaga
    51361 ttaaacgatg acatgaaaac agcgatgaaa gcgaaagata aggaatcttt acaagtcatc
    51421 cgaatgatca agtcatctat acaaaacgag cagattaaag aaggtcacga cttgacagaa
    51481 gaagaagaat taacggtgtt gtctcgcgaa atgaaacagc gacgtgattc tttgcatgag
    51541 tttgaagaag caggacgtga cgatttagct gaaaaagtaa aaagtgaaat tgtgatagtc
    51601 gaaaaataca tgccggaaca actttccgac gaagaaattc gacaacttgt tcaagaagca
    51661 atcacacaaa ctggtgcttc atcaatgaaa gaatttggca aagtcatggg tgcgatcatg
    51721 cctaaagtca aaggaaaagc agatggaaac caagtaaatg ccattgtgaa agaactatta
    51781 caatcttaat tttatcattt aaactgcgga caatcattgt ccgcagtttt tttgtgcgcg
    51841 taaaaaagag aacaaaaaaa tagctagacg aaagaatagg attctttcat ctagctggtt
    51901 ttttcctgtt taatatttct tatgttaaat tgtgtttgat ttggttattc ttctggtagt
    51961 tcatttgctt cttgtttata ccctgatagg cgataggcgt aataaaacag taggctgcca
    52021 gcgtaaccaa gtaacgttgg gaccatccag ccaagtccta atgcagcaaa aggaacgtga
    52081 tgatgataaa attcgagcat gcttgctaca actctttgtt gactcactaa agcaggcgaa
    52141 tttgccagca tatccaatac ggcaggaaca gcagcaaaca acatcgttac ttgatagaca
    52201 aatggtgtct tttggaaaaa ttttgctgtt aaggaaagca agatcaacgc aagcgacaat
    52261 ggatacaaaa gcatcaatac tggtaaagac cattggatga tattgtctaa accagcattt
    52321 gcaacgacaa aagagacgaa agtcgttaac cgcagccatg tcatataact gactttaggg
    52381 aacagtttat ggaaatcttg cgcaaaagaa acaacgagtc ccatagcggt agtgaagaca
    52441 cctaatgtga ccatcactcc taagaagcta gcgccgaagt tacctaaata aaaattagtg
    52501 atctgagaaa gtgcagttcc gccattttct gataaagaca tcttattcaa actcatcgca
    52561 ccgagaagaa caagaccaaa atagatcatg acttctagcg caacgctcag gctaccagct
    52621 tttgctgtta attctgtgac ttttttatct ttgaaaccaa ggtcacggac tgcatggaca
    52681 aaagtgacac ttaaggcaag caaggctact gcatcaaccg tgttataacc ttctaggaca
    52741 ccatttgtta aagcgtttgt ttggtaagta tctgcagcag attgatttag atttcccatt
    52801 gggtggaata aagaaacgac aaaaatgatt gctaacaatg caagaaacaa ggagtttaga
    52861 tactttccga cgtatttgac caaccgtgtg ggatggacag taaggaaata agcaagtaaa
    52921 aagaaaagag cagagaataa aaacatacct aatgaattat atttttcagg caaaaatggt
    52981 ttagcagcca tttcaaaagc agtagcagct gtccgtggtg taccgaaaaa tggtccgatc
    53041 gtcaaatgaa caaggattaa gaacaaggca gcataccatt ttccgacagg tttagctaag
    53101 tcatacagac catcactttt tgtcactact acagctaaga tagctagtaa tgggaaaaga
    53161 gcgcccgaga tggcaaatcc tacgccagca ctgacccagt ttgcgccagc catttgacct
    53221 aagtggacag gaaagattag attacctgac ccgaagaaca tcccgaagat aagtgaactg
    53281 accatcaata gttgtttcca tgaataagtt tttgtttctt ccataaattt ttcctccaat
    53341 aattatcatt ttgattgacg atataaacgt tgcagcaatt agtaatgcca ctaatatcag
    53401 attccatgaa aaccaccacc ttaaaatata aaaaaagccc ttttccactt gggaaaaggg
    53461 ctctagattc tagaacggta ccaccttttt tcgcttaaaa aagcttcttc attcacggac
    53521 gctttttgat aaagttatcc gctagcctga taatggaggc agccacaatg atctacgttt
    53581 tcgacattga ctcggaaatg atgttcgtct attcgattta ttgtcatttc tcacttacat
    53641 gactcactgg gaataaatcg ttgaatagcc tactgttttc ctcgacgctt tgctgtatgt
    53701 ttatttgttg acgtaataat acacctgttt tttttgaaat gcaagaatat tttaactatt
    53761 ttgttttctt tttttgaaac aagaaaaata cctagagaat acctgctgaa tgaaacggaa
    53821 tattttgttc tccactttca tataacttac attctcagct tctttttatc aaaacgagac
    53881 ctttagcgaa tggaaacggc tattttttaa cgtttcttgg tacgtatggt taaacgactc
    53941 ttttacaacc ttttcttatt tgctatatag tttcttctga gtatggtaaa ataggaaaga
    54001 atgaatcgaa aaaaagggga tgtctatttt tgacggaaga gtctagttct ttagagatta
    54061 gattgacagc tgctgatgat gtcagcatgc ttttaggtgc acacgacaag catataaaac
    54121 tgatcgagga aacaacggaa acaaccatcc atacacgtgg agaaatcatt cagatcattg
    54181 gtgagcaatc ccagatttcc ttggctgcct cagtcattcg gacattacag gaattgatca
    54241 aacgaggaat ccacgtaagt acgccagatg ttgtgacggc attgaagatg gggcaaaaag
    54301 gtacattaga ttattttgtt gagatgtatg aggaagagat cgtcaaagac cgtaatggaa
    54361 aacctatacg ggtaaaaaac agcggtcaaa agaaatacgt tgaatcggta gccaaacatg
    54421 acatcgtatt tggtgtaggg ccagccggaa cagggaaaac gtttcttgcc gtagtattag
    54481 caattgctgc cctaaaaaaa ggcgaagtgc aaaaaatcat tttgacgcgg cccgctgtgg
    54541 aggcagggga aaacctaggc tttctacccg gggatctgaa agaaaaagtg gatccttatc
    54601 tgcggcctgt ttatgatgct ttataccaaa tttttggatt ggatcatacg aaccgattga
    54661 tggaacgagg cgtgatcgaa atcgcacctt tagcttacat gcgggggcgg acattggatg
    54721 atgcattcgt tatcttggac gaagcacaaa acacgacagt cgctcagatg aaaatgttct
    54781 tgacccgtct cggttatcaa tcaaaaatga ttgtcaatgg ggatacaagt cagatagact
    54841 tgcctcgtgg gacgacaagt ggtcttgttc atgcagaacg aacattaaag caaatcaaaa
    54901 aaatcgattt tgttaatttt gaagcaagtg acgttgttcg gcaccctgta gttgccgaaa
    54961 tcatcaaagc ttatgaaaag gcggatcttc atcaagaata agctttgctt aggaggataa
    55021 gcacatgttg aataaaacac tgcagaaact acaaaaaaaa ctcggaaagg cagcattgcc
    55081 tttccttctg ttcttgtttt ttatcattgt ctgcggcgtt acatttagta gtgtcaaaca
    55141 aaaggccaat gatttcagag aaggccaagt agcagaagag agtatccgtg cgaataaaac
    55201 gattgagaac acggaagaaa ccgaacaaag aagaaaactg gcagcagaag cagtgactcc
    55261 agaatatact tatcaaaaag atctggcaga tgaccagaac aatcggatca agcaattatt
    55321 cgaattgatc gataagacga atgataccat caacaaatct tataatgaca aggtagataa
    55381 ggcgaaggaa gatgaaaata tcccgaaacc tactacagaa gagcggattg ctacactgaa
    55441 gaaaaatttt gaaaacgtga atgcagaaaa cgttgcgttt taccaaaaac tgccgaacaa
    55501 tttttattcg acgatatttg aaatgactga aacggaaatt cacacggtta gggatgaaag
    55561 tttgaagctc attgacgaac agatgagtaa acaagttcgt gaaagcgaat tggaagcttt
    55621 taaacaagaa gcagaagatc agattcaata tttgaatgtc acaacagagc agcaacaaat
    55681 gattcgctac ttagtggatc aaggcattgt agttaatgat gtattgaatg agaaaaagac
    55741 agaagaatta aaacaatctg cacgagaagc tgtacaacca gtgatgatct tccaaggaga
    55801 aattattgtt cgcgaaggaa atcaaattga tgcttcagcg atgaaaaaat tggaattact
    55861 aggattgacg aatcaaacga cttctatttt cccactcatt gccatggttt tagctgtttt
    55921 gcttcaaatc ggtgtactga tttataattc acttcaattc caaaatgcag gagaaagaac
    55981 aaaatacgta cttttctacg tgacggcaat gtcagtaagc gtcgtactaa tgaaattttt
    56041 ccaactcttc caaacagaac aagctgctta tattccgctg ttttaccccg cggcttttgc
    56101 tccacttgtt ttaagctttt tcttgaatcg aagagcaggg atcatggctg gtatttttca
    56161 agcagtatcc gcacttttca ttttttatga ttcgattggc acgaactttc tgacagttat
    56221 tttgatgtcc tatgtatttt ctggtctcat ggcaacgatc gtcagacgca aacggatctc
    56281 agaacaaggg ttatccgctg ctatgtgggt cattattttt cctgtgatga tggatgtcat
    56341 tttgattatc taccaaggaa tgagctttgg ggatgcaacg acttggttaa cgctagtatg
    56401 cggattcaca ggtgcactgt tctcattctt gctgacgata ggtctgcacc cctatattga
    56461 attgatggtc aatgatgata gtgtgatcgt attaaatgaa ctcagcaatc ctaatcatcc
    56521 tttattgaaa cagttgctgg aagaagcacc aggcacgtat caccatagca tgatggtagc
    56581 caatctaagt gctaatgctg tagcagaaat cggtggacgt tctttactaa ctcgagtagc
    56641 ttgctattat catgatatcg gcaagatcaa acacgccagc tttttcgttg agaacttgcc
    56701 ttcaggagcg gaaaatccgc acaatttctt attgccagaa gacagtaaac atattatctt
    56761 tggacatgtg acagatggtg ccaaaatatt ggaagattat aatatgccgc aaatggtgat
    56821 cgatatttgc agacagcatc atggaaccac gctgatgcgt tatttctacg ttaaggcaaa
    56881 ggaacgcaac ccggaagtca cggaagagca attccgttat cctggaccaa aacctcaaag
    56941 ccgtgaagca ggaatcgtca atatagctga cagttgtgaa gcggcagtac gagcaatgga
    57001 ccatccaacg agcgaaaaaa tcgaaagttt tgtccataat cttattgaag agcgtatttc
    57061 cgatggacaa ttggacgaca gtggattgac gttaaaagaa atccgtaaag tagaaaaatc
    57121 attgatcagc ggtttaagca gtaccttcca ttctcggatc aaatatccta aaatgaaatc
    57181 ggaagttgag aagataaaag aagaacaaga agaatagaaa gaagcgatgt ataatggata
    57241 ttactttcat ggatgaaaca aaccaagtct cagaagagaa aatgaaagaa atcgacgact
    57301 tgctgcaatt tgcagcatca tatttagagt tgccagaaga aacagaaatg tctgttactt
    57361 tcatggacaa tgcagcgatc caagtaatca atcgtgatta ccgtggaaaa gatgcaccga
    57421 cagacgtcat cagttttgcc ttggaagaag agggcgaaga cgaaatccca gtgatttttg
    57481 aagatggaga gaatccattg cctcgtgtac tgggagacat catgatctct actgaacgtg
    57541 ctgcagagca agcagaagct tacggccatt cgtatgatcg ggaacttggc tttttagcgg
    57601 ttcatggatt cttgcatatc aacgggtatg accatatgac accagaggat gagaaagaaa
    57661 tgtttggttt acagaaagag atcttagatg cctatggact taaaagataa aaacgtagag
    57721 aaaaacaaac atttcctgat gtccgtggaa tttgccgtcc aaggagtcaa aaccgttttt
    57781 gaggaagaac gcaacatgag gaaacatgtt gcgttcggaa tcctcgcttt gtttatgggc
    57841 gtgattttcc agcttgatcg gatagaatgg ttatggctgc ttttagctgt ttttctcgta
    57901 tggatagtag agatcatcaa tactgttttt gaaaatgtcg tggacatgtt tacggatttt
    57961 cattttcatc cgattgggaa aaaaatcaaa gatatggcag ctggagcagt tttagtgacc
    58021 gcttgttttt ccgtcatcgt tgggttgatt ttatttgtcc ctaaaatata tcatttgttg
    58081 tttaattaaa aaggagaacg tatatgccag aacataaatc agggtttgtc gcaatcgtcg
    58141 gccgcccgaa tgtaggaaaa tccacattat tgaatcgaat cgtgggtcaa aaaattgcca
    58201 tcatgagtga taaggcgcag acaactagaa ataaaatcca aggagtatat actacaccag
    58261 aagctcagtt gatttttatt gacacaccag gaatccataa accaaagcat cgtttaggag
    58321 attttatggt agaagcagct tacagtgcgt tgaaagaagt ggacgcggtc ttatttatga
    58381 tcagcgctga tcaaaaacgc ggtcggggag acgattttat tattgaacgt ctaaaaaacg
    58441 tgcattctcc tgtttatctg attatcaata aaatcgataa aatccatcca gacgagttgt
    58501 tgggaatcat cgaagattat tcaacgcaga tgccgtttgc acaagtgatt ccaatttctg
    58561 ctacagaagg aaacaacgtc gaacgtttga tggatgtatt agtcagtgaa atgccagagg
    58621 gcccacaata ttttccagat gatcaagtga ctgatcatcc tgaatacttc atcgtttctg
    58681 aattgatccg tgagaaagtc ttgtttttaa cacgagacga agtgcctcat tctgtcgcag
    58741 tcgttgttga ttcgatgaag cgaaacgaga atgataaaat ccatatccag gctacgatta
    58801 ttgtcgaaag agatagccaa aaagggatca ttatcggcaa aggcggaaaa atgctgaagc
    58861 aagtaggaac gaaagcgaga aaagatatcg aaaatctttt aggagacaaa gtctttctag
    58921 aactttgggt caaagttcaa aaagactggc gagacaaaaa agtctatctg caagacttcg
    58981 gctaccgaaa agacgaatat tgatattctg agcttcttgt aagttaggta tagaaataaa
    59041 ctggataaaa atccgcgtgt tgagaaaagc tgcggaagat cgcaacataa atgatctgga
    59101 tcggcagaat ctgcttttcc agatttattt tttaggaggg agaatatgag ccagcttgca
    59161 gaatcaaaag gcttgatttt atctagccgt aattacaaag aaaaagataa attagtcaaa
    59221 atctttacgg aatcttctgg caaaatgatg ttttatatca aagggatcca tcggcaaaat
    59281 cagcccttag ctccggcttt gctccctttt actgaagcag tttatatcgg gaattttcga
    59341 agtgaaggtt tgtcattttt aagcagtgtc aaagatgtcc acgcgtttcg acacatccaa
    59401 gaagacatct ttttgagcgg ctatggcaca tatttattga atctagtaga tgcggcaatc
    59461 gaagatcatc agtacgaccc gcatttgttc cagtttacgc aacaagcact gcaactgatg
    59521 gaccaaggag atgatgcaga aatcatcacg aatatttttg aagtccaaat actgcaacgc
    59581 ttcggaattg caccaatctg gacacactgc gtcgtatgtg gggaaacaaa aggaaaattt
    59641 gactattctt ccaaatatgg tggtgtgata tgcgaaagac actggtcgat ggatgatcac
    59701 cgttatcatg cagatcctcg agctgtttat ttcgttcgga tgttttcagc tatttcttat
    59761 gataaaatca gtggaatcca tctgaaagaa gaaaccaaac aagcaatccg tgaactcatc
    59821 gaccagctgt atgatgaata tgtcggtatc catttgaaaa gcaaaaagtt cattgatcaa
    59881 atgaagtctt gggcacacgt attaaagacg tcagagaaag acatgtctga aaaagatcta
    59941 cctaaaaaag aagaatagta aatgaaacat acaacaaaaa atcaaaacca tttgacaaac
    60001 acagggagtt ccgtctatta ttaaccgtag atcaaataga tcgttcactg agaggatcta
    60061 ttatagaaac aagaaaactg caaaatgaat acgtacattg accaagatca gtaaaaaaca
    60121 cgtggtttag cgagttcggg agagtgggag ccggacccaa acgatttttg aagaggcact
    60181 tgcgagtacg ataaatgaag ctgccgaatc tttattcgga agtagggtgg aaccgcgaat
    60241 tattcgtccc tatgtctgta atcagacata gggatttttt gtcgttttct ttcctgtatt
    60301 cttatttgac agcaacgctt taaaattgaa aggggcaaaa cagatgagta aaaaattgac
    60361 cgtccaagat atgattttaa cattacaaaa attttggtca tcaaacggct gcatgctgat
    60421 gcaagcgtat gacacagaaa aaggagcagg tacgatgagc ccatatacct ttttacgggc
    60481 aatcggacca gaaccatgga atgctgctta cgtagagcca tctcgccgac cagctgatgg
    60541 acgttatggc gaaaacccaa accgtttgta tcagcatcat caattccaag tcgtgatgaa
    60601 accttcacct gagaatatcc aagagcttta tttagaaagc ttgcgccttt taggaatcga
    60661 tccactagaa cacgacatcc gttttgttga agacaactgg gagaacccat ccatgggctg
    60721 tgccggtgtg ggttgggaag tatggcttga cggaatggaa atcacacaat tcacgtactt
    60781 ccaacaagtt ggtggactgc cttgtaaacc agtaacttct gagatcactt atggattaga
    60841 acgtcttgct tcttatatcc aagaagttga aagtgtctat gatttagaat gggctgatgg
    60901 cgtgaaatat ggcgagatct tcaaacaacc agaatatgaa cattctaaat attcttttga
    60961 agtaagcgac caagacttgc tactaagcaa ctttgatcgt tttgaaaaag aagctaaacg
    61021 ctgtatcgat gaaaatcttg ttcatccggc gtatgattat atcttgaaat gtagccatac
    61081 attcaactta ttagacgccc gcggtgcagt atccgtaaca gagcgtgccg gttatctttc
    61141 tcgcatccgc aacatggctc gtgctgtagc caaaatcttt gtggcagaac gcgaaaaatt
    61201 aggattccct ttgttgaata aaaacacagc aaatccagaa aacgtgaagg aggctgaata
    61261 agatggcaaa agacttatta cttgaaatcg ggctggaaga aatgcctgct catgttgtca
    61321 caccaagcat gaaacaatta gaagaaaaaa cagcaaaatt tttagatgaa aaccaattga
    61381 cttatgatac gatcgaaaca ttttccacac cgcgccgttt agcaatcaaa gtaacaaaca
    61441 ttccagaacg acaagcggac agtgaagaag aagtcaaagg accagccaaa aaaattgctt
    61501 tggacgcaga tggaaactgg acgaaagcag cggaaggatt tgtccgcgga caaggtctga
    61561 cgacagacgc tatcactttt agagaattaa aaggtgtgga atatgtctat gtaacgaaat
    61621 acactcatgg taaggaatcc aaagaagtat tgacaggttt agcagatgtc attaaaagcc
    61681 tgactttccc tgtaacgatg cattgggcag aatacgattt tgaatatatc cgccctattc
    61741 actggatcgt ggcattgtta gatgacgaag taatcccatt cgaaatcttg gatgtcaaaa
    61801 caggcagagc ctctcgaggt catcgtttct taggcgaaga tgtgacattt gcgcatgcaa
    61861 aagaatatga agaaaaattg aatgaacaat tcgtcattgc gtctccgcaa aaaagacaag
    61921 aaatgatcgt tacacaagcc aatgaattag ccgaaaaaaa tcattgggtt attgatctag
    61981 acgaagattt actagaagaa gtcaacaatt tagtcgaata tccaactgtc ttttctggcg
    62041 acttcgaaga aaaatatctt tctgttcctg aagaagtact agtcacttct atgaaagaac
    62101 atcaacgtta tttcgaggta cggaatgatc aaggtatgct gcttcctcat tttatttctg
    62161 ctcgtaatgg tgatcgggta aaattggaaa atgtggttcg aggcaatcaa aaagtattga
    62221 cggctcgttt agaagatgcg gaattctttt ataatgaaga caagaaagct tcaatcgacc
    62281 aatacgttga aaaactaaaa actgttactt tccatgaaaa aatcggtagt atctatgaga
    62341 aaatgcaacg ggtacaagtc attgcccgta tcattggcga acaagtagga ctatctgagg
    62401 aagaattgat ggatctgcaa cgagctgctg aaatctataa atttgatcta gtaaccaaca
    62461 tggtagggga atttcctgaa ctgcaaggga tcatgggcga aaaatatgct ctgctgaaag
    62521 gcgagaaacc tgctgtagcg acagcgattc gtgagcatta catgcctata tccagtgaag
    62581 gagagctacc tcagtctaca gtaggttctg ttttagcgat tgcagataaa ttagatagca
    62641 tcttttcttt ctttgctgtt gggatgatcc caagcggttc aaacgatcct tatgccttac
    62701 gtcgccaagc atacggtgtc gttcggatca tcgaatcgaa aaaatgggcc tttcctttgt
    62761 ctgttctgca agaaacgatt agcgatgtta tcagtaaaga tacggatcgt ttcggcattg
    62821 gtttatcaga agggcaacaa caagtgatcg actttatcaa aggccgtctg cgccaattat
    62881 tgacaacgaa gaatattcgt catgatgtca tcgatgctgt tttgaatgcg gaacaaaaag
    62941 atctgacaaa agtatttgca gcagcacaat tgttcaaaca acatcttgca gatgaagact
    63001 tcaaaccttc aatggaagct ttgacacgtg tcgtgaactt agcgaaaaaa gcgcagcttg
    63061 aaaaacaatc agaagtagat cctgagctgt tcgaaaacga cgcagagaaa gaattacaca
    63121 aagcagtaga agcaatgaaa gcaagttttg ctgaccaaac gatccacgaa aactacgacc
    63181 agcttgtcgc tcttcgtcca ctgatcgaaa attattttga tcaaacgatg gtcatggctg
    63241 atgaaccagc agtacgtaag aaccgactaa cacaacttag tcaaatagct gccatggctt
    63301 tgtcattagc aagcttggat caaatcatca caaaatagtc ttttgtttga aaaacagaga
    63361 gcatgcacga aacgtgctgt gtctctg
//
LOCUS       DAYNVV010000007        63156 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.007, whole genome shotgun sequence.
ACCESSION   DAYNVV010000007 DAYNVV010000000
VERSION     DAYNVV010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 63156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.007"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..96)
                     /locus_tag="ACGXWR_000604"
     rRNA            complement(<1..96)
                     /locus_tag="ACGXWR_000604"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            837..1526
                     /locus_tag="ACGXWR_000605"
     CDS             837..1526
                     /locus_tag="ACGXWR_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFK0802216.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1513..2721
                     /locus_tag="ACGXWR_000606"
     CDS             1513..2721
                     /locus_tag="ACGXWR_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFK0802217.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            3015..4286
                     /gene="serS"
                     /locus_tag="ACGXWR_000607"
     CDS             3015..4286
                     /gene="serS"
                     /locus_tag="ACGXWR_000607"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFK0802218.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4835..6319)
                     /gene="guaB"
                     /locus_tag="ACGXWR_000608"
     CDS             complement(4835..6319)
                     /gene="guaB"
                     /locus_tag="ACGXWR_000608"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HFK0802219.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6824..7519)
                     /locus_tag="ACGXWR_000609"
     CDS             complement(6824..7519)
                     /locus_tag="ACGXWR_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HFK0802220.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7609..8709)
                     /gene="ychF"
                     /locus_tag="ACGXWR_000610"
     CDS             complement(7609..8709)
                     /gene="ychF"
                     /locus_tag="ACGXWR_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HFK0802221.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8718..8909)
                     /locus_tag="ACGXWR_000611"
     CDS             complement(8718..8909)
                     /locus_tag="ACGXWR_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HFK0802222.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8930..9820)
                     /locus_tag="ACGXWR_000612"
     CDS             complement(8930..9820)
                     /locus_tag="ACGXWR_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HFK0802223.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9807..10574)
                     /locus_tag="ACGXWR_000613"
     CDS             complement(9807..10574)
                     /locus_tag="ACGXWR_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFK0802224.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10586..11299)
                     /gene="rsmG"
                     /locus_tag="ACGXWR_000614"
     CDS             complement(10586..11299)
                     /gene="rsmG"
                     /locus_tag="ACGXWR_000614"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HFK0802225.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11531..13432)
                     /gene="mnmG"
                     /locus_tag="ACGXWR_000615"
     CDS             complement(11531..13432)
                     /gene="mnmG"
                     /locus_tag="ACGXWR_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HFK0802226.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13449..14846)
                     /gene="mnmE"
                     /locus_tag="ACGXWR_000616"
     CDS             complement(13449..14846)
                     /gene="mnmE"
                     /locus_tag="ACGXWR_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HFK0802227.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            15145..15528
                     /locus_tag="ACGXWR_000617"
     CDS             15145..15528
                     /locus_tag="ACGXWR_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802228.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15696..16454)
                     /gene="jag"
                     /locus_tag="ACGXWR_000618"
     CDS             complement(15696..16454)
                     /gene="jag"
                     /locus_tag="ACGXWR_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HFK0802229.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16472..17290)
                     /locus_tag="ACGXWR_000619"
     CDS             complement(16472..17290)
                     /locus_tag="ACGXWR_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HFK0802230.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17287..17643)
                     /gene="rnpA"
                     /locus_tag="ACGXWR_000620"
     CDS             complement(17287..17643)
                     /gene="rnpA"
                     /locus_tag="ACGXWR_000620"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFK0802231.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17761..17895)
                     /gene="rpmH"
                     /locus_tag="ACGXWR_000621"
     CDS             complement(17761..17895)
                     /gene="rpmH"
                     /locus_tag="ACGXWR_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HFK0802232.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18418..19752
                     /gene="dnaA"
                     /locus_tag="ACGXWR_000622"
     CDS             18418..19752
                     /gene="dnaA"
                     /locus_tag="ACGXWR_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HFK0802233.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19950..21080
                     /gene="dnaN"
                     /locus_tag="ACGXWR_000623"
     CDS             19950..21080
                     /gene="dnaN"
                     /locus_tag="ACGXWR_000623"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HFK0802234.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21309..21551
                     /gene="yaaA"
                     /locus_tag="ACGXWR_000624"
     CDS             21309..21551
                     /gene="yaaA"
                     /locus_tag="ACGXWR_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HFK0802235.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21538..22662
                     /gene="recF"
                     /locus_tag="ACGXWR_000625"
     CDS             21538..22662
                     /gene="recF"
                     /locus_tag="ACGXWR_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HFK0802236.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22659..24605
                     /gene="gyrB"
                     /locus_tag="ACGXWR_000626"
     CDS             22659..24605
                     /gene="gyrB"
                     /locus_tag="ACGXWR_000626"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HFK0802237.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24625..27096
                     /gene="gyrA"
                     /locus_tag="ACGXWR_000627"
     CDS             24625..27096
                     /gene="gyrA"
                     /locus_tag="ACGXWR_000627"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HFK0802238.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27332..27631
                     /gene="rpsF"
                     /locus_tag="ACGXWR_000628"
     CDS             27332..27631
                     /gene="rpsF"
                     /locus_tag="ACGXWR_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HFK0802239.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27681..28193
                     /gene="ssb"
                     /locus_tag="ACGXWR_000629"
     CDS             27681..28193
                     /gene="ssb"
                     /locus_tag="ACGXWR_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFK0802240.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            28219..28455
                     /gene="rpsR"
                     /locus_tag="ACGXWR_000630"
     CDS             28219..28455
                     /gene="rpsR"
                     /locus_tag="ACGXWR_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HFK0802241.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28598..30571
                     /locus_tag="ACGXWR_000631"
     CDS             28598..30571
                     /locus_tag="ACGXWR_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HFK0802242.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30577..31029
                     /gene="rplI"
                     /locus_tag="ACGXWR_000632"
     CDS             30577..31029
                     /gene="rplI"
                     /locus_tag="ACGXWR_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HFK0802243.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31303..32670
                     /gene="dnaB"
                     /locus_tag="ACGXWR_000633"
     CDS             31303..32670
                     /gene="dnaB"
                     /locus_tag="ACGXWR_000633"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFK0802244.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33450..34742
                     /locus_tag="ACGXWR_000634"
     CDS             33450..34742
                     /locus_tag="ACGXWR_000634"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HFK0802245.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35478..36341
                     /locus_tag="ACGXWR_000635"
     CDS             35478..36341
                     /locus_tag="ACGXWR_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFK0802246.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36470..38092)
                     /locus_tag="ACGXWR_000636"
     CDS             complement(36470..38092)
                     /locus_tag="ACGXWR_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFK0802247.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            38341..38862
                     /locus_tag="ACGXWR_000637"
     CDS             38341..38862
                     /locus_tag="ACGXWR_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFK0802248.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(39048..40778)
                     /gene="spxB"
                     /locus_tag="ACGXWR_000638"
     CDS             complement(39048..40778)
                     /gene="spxB"
                     /locus_tag="ACGXWR_000638"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HFK0802249.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            40943..41761
                     /locus_tag="ACGXWR_000639"
     CDS             40943..41761
                     /locus_tag="ACGXWR_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HFK0802250.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41864..42061)
                     /locus_tag="ACGXWR_000640"
     CDS             complement(41864..42061)
                     /locus_tag="ACGXWR_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802251.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            42230..42808
                     /locus_tag="ACGXWR_000641"
     CDS             42230..42808
                     /locus_tag="ACGXWR_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFK0802252.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            42903..43040
                     /locus_tag="ACGXWR_000642"
     CDS             42903..43040
                     /locus_tag="ACGXWR_000642"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802253.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(43853..44356)
                     /locus_tag="ACGXWR_000643"
     CDS             complement(43853..44356)
                     /locus_tag="ACGXWR_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFK0802254.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            44715..45740
                     /locus_tag="ACGXWR_000644"
     CDS             44715..45740
                     /locus_tag="ACGXWR_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFK0802255.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            46063..46941
                     /locus_tag="ACGXWR_000645"
     CDS             46063..46941
                     /locus_tag="ACGXWR_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase domain-containing protein"
                     /protein_id="HFK0802256.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            47417..47533
                     /locus_tag="ACGXWR_000646"
     CDS             47417..47533
                     /locus_tag="ACGXWR_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFK0802257.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            48461..48799
                     /locus_tag="ACGXWR_000647"
     CDS             48461..48799
                     /locus_tag="ACGXWR_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802258.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            48893..49123
                     /locus_tag="ACGXWR_000648"
     CDS             48893..49123
                     /locus_tag="ACGXWR_000648"
                     /inference="COORDINATES: protein motif:HMM:NF042636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6568 family protein"
                     /protein_id="HFK0802259.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            49523..49894
                     /locus_tag="ACGXWR_000649"
     CDS             49523..49894
                     /locus_tag="ACGXWR_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HFK0802260.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(50168..50860)
                     /locus_tag="ACGXWR_000650"
     CDS             complement(50168..50860)
                     /locus_tag="ACGXWR_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFK0802261.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(50863..51648)
                     /locus_tag="ACGXWR_000651"
     CDS             complement(50863..51648)
                     /locus_tag="ACGXWR_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFK0802262.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            51885..53285
                     /gene="lacG"
                     /locus_tag="ACGXWR_000652"
     CDS             51885..53285
                     /gene="lacG"
                     /locus_tag="ACGXWR_000652"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFK0802263.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            53310..53627
                     /locus_tag="ACGXWR_000653"
     CDS             53310..53627
                     /locus_tag="ACGXWR_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFK0802264.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            53640..55313
                     /locus_tag="ACGXWR_000654"
     CDS             53640..55313
                     /locus_tag="ACGXWR_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HFK0802265.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            55327..56958
                     /locus_tag="ACGXWR_000655"
     CDS             55327..56958
                     /locus_tag="ACGXWR_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-beta-1,4-galactanase"
                     /protein_id="HFK0802266.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            57830..59020
                     /locus_tag="ACGXWR_000656"
     CDS             57830..59020
                     /locus_tag="ACGXWR_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HFK0802267.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            59154..61343
                     /locus_tag="ACGXWR_000657"
     CDS             59154..61343
                     /locus_tag="ACGXWR_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFK0802268.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            61340..63133
                     /locus_tag="ACGXWR_000658"
     CDS             61340..63133
                     /locus_tag="ACGXWR_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HFK0802269.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLY
                     KFVTKHIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGI
                     TLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNL
                     FLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
BASE COUNT        19706 a        11437 c        12455 g        19558 t
ORIGIN      
        1 gtggagcaag ctccggtgga aaaagaagcg ttcgacttgc atgtattagg cacgccgcca
       61 gcgttcgtcc tgagccagga tcaaactctc ataaaaagtt cgaacaatct tgcgattgtt
      121 aagctcaatt tgtttgctag catattgctt gcttgttaaa aatgtttgtt gtcttgaatt
      181 gaatcaagac gccctacaca tttggtttgt cttactttgt tcagttttca aaggtctact
      241 tcatcaggag tgtttcccga ttcgtttttg gctgccgtag caacttttat atcatatcag
      301 agagacaagt aattgtcaac tcttttttaa aagttttttc gatttcgttt ttcgaaatct
      361 tccagcaact catttatcat aacttatcgt ttgttatttg tcaagaactt ttttgaagtt
      421 tttttcgata gaatcaagct tcgcaagtgg ttctttttta acgactcagt tatcttatca
      481 tgtcatttcc aacatgtcaa caacttattt tttattattt aataagttat tggtgttctt
      541 ttgaacaaat aataatatat caacatcaca tgtgaaagtc aataagaaaa tgcttattta
      601 tcaacatttc tagcttacat gatcattggt tagttctggt cctttttcgt tcgtctttat
      661 aactccgaga gacgtaaaat ccttttgttt tcagtttaat gttcatgttc ttgtcttatt
      721 cacaccaact agatgtctca ccttctaaaa ttttccttaa caaagtgctg cttttatcta
      781 tttctgcttt tttttgctag aataatagta acaatatgac tctggaggat ttatttatga
      841 aaattttgat tgctgacgat gataaagaaa tcgttgaatt attaagtatc tatgttcaca
      901 atgaggggta tgaagcagta aaggcttatg atgggaaaga agcattatct aaaatcagaa
      961 caatccctga tattgaatta cttattttag atatcatgat gcctgagatg gatgggatgc
     1021 aagtagtgaa agagctacga aaagaatccc aaataccaat cattatgctg acagcaaaaa
     1081 ctactgatat ggataagatc aaaggactgg tcgctggtgc agatgattat gtgaccaagc
     1141 catttaatcc gttagaagta atggctagag taaagtcttt attacggcgt acaaaaatgc
     1201 agattgcccc agatcagcct gatgtattag aagtaaatgc attaatcatc aataaagact
     1261 ctcatgaagt taaaacaatc gatgggaaag aaatccagtt aacagctttg gaattcggta
     1321 tcctctactt gcttgctagt catcctaatc gagtatttag cgcggatgaa atttttgagc
     1381 gtgtttggaa acaagaaagt attgtctctg ctaaaactgt catggttcac gttagtcatt
     1441 taagagataa gattgaagaa gcaactggtg gtgaaaaagt cattcaaacc gtttggggag
     1501 tgggctataa aattgacgca agatagtaaa cgagcaactg aaaaacgccg tcggatcaat
     1561 ttgacttcaa aagaaatcag cgaattgtta gcggaaggaa tcatcacgat tatccttttg
     1621 cttctattaa atgtttctat tctggttgtt atcagttcgg tgatcaacag ttcaccttct
     1681 ttgacgaatg cgatttggga ttcaaagaat atttttgcag aacgattgaa cactgatttg
     1741 ttctggaacg gccggaattt tattattccc tttttctttc tattagatat tggtgttttg
     1801 tattggcgct tgattcgaag atatcgccaa atgcaattgc ggcatatcat cagcgaactt
     1861 cactacatcg caaacggaaa ttatgatcat cgtatccctt ttgaactgag tggtgactta
     1921 agccgagtgg taacaagtat caatggattg gtggatagta ccgtagcagc gattgaagac
     1981 gaacgtaaaa tcgaaaaatc aaaagatgaa ttgatcacga atgtcagtca tgatatccgt
     2041 accccactca cgtccatcat tggataccta ggactgatag aagatggcca gtatcactca
     2101 gaagaagatc ttttaaagta tacgcatact gcttatatca aagcaaagca gatgaaatct
     2161 ttagtggacg acttatttga atacactaag gtacgccagc ctgctgtccc ggtgaatttt
     2221 tctgcctttg acatgatcca gttgatcgaa cagttagcag ctgattttga gttggaagct
     2281 tctaaaaaaa atatccaaat acttgttcaa tcaaaagtag actcccttat catggatggc
     2341 gataccgaaa aacttgtacg tgtcttcaat aatcttttga cgaatgcgtt gaaatacgga
     2401 aaaggagcaa cgaagatcgt aatcgaagta gaacgtatcg gttcagaagt tgttgcaaca
     2461 gtcaaaaata acggagcaat gatcccacaa caggcaatcg ataatctatt cgaccgtttt
     2521 tatcgtgtag aagaatctcg ttcacaagca actggaggaa ctggacttgg tttagcaatc
     2581 gctcaaagca ttgtggcttt gcacggcgga tacatttatg caaaatcaga taagcaatgg
     2641 acttctttca tcatgcacct tccaatcaag aaaaatgaaa aattacctat tgatacacag
     2701 gaagttattg acgaaagctg aaatattcgc tattcttatt acaattatta gaataaatga
     2761 aaaacacaga acccagtaca ctttattctt tttcagagag ctgatggcag gtgtaaatca
     2821 gcaaaggata atttggaagt tccagttcgt ttacgtgccc tttcgaaata agaaaggtcg
     2881 gttcaacagc cgttatgtgt tcaacaagtg cagctgacgc tgaacttggg tggtaccgcg
     2941 aatttcagac tgattcgtcc caagaataat gggatggatc agtctttttt tattttcaaa
     3001 aaggaggaaa tcatatgtta gatgtaaaaa tgatgcgaca aaatattgaa gaagtacaag
     3061 aaaaattgat gactcggggc gtaaaaaaag aaacattagc tgaattcatg gaactagatg
     3121 aaaatcgtcg taagctacta gtcaaaagtg aagaattaaa aaaatatcga aatgatgttt
     3181 ctgctgagat cgcccaattg aagcgtgcaa aagaagatgc ttctgctaaa atcgctgaaa
     3241 tgaaagaagt cggtggcaac atcaaagcat tggatactga aattgctgaa gtggatgaaa
     3301 aattgaaaca aattgcaact actttgccaa accttcccca tgattctgtg ccagttggaa
     3361 cagatgaaga ggacaatgta gaaatccgtc gttggagcga accacgtaca tttgcttttg
     3421 aaccaaaacc acactgggaa attgcagaaa atcttgatat tttagatttt gaacgtggcg
     3481 caaaagtagc cggtagccgt tttgtctatt acaaaggatt aggtgctcga ttagaacgtg
     3541 ctgtctacaa cttcatgctt gatcagcata tttacgaaca cggctatact gaaatgatca
     3601 ctccttatat cgtcaacagt aaagcgatgt ttggtacggg acaatttcca aaattcaaag
     3661 aagatgtttt ccaattggag aatactgatc taacattaat cccaacagct gaagtaccat
     3721 taactaacta ttataatgat gaaattttag atggtgcaga tttacctatt tatttcactg
     3781 cactaagccc tgcttttcgt tctgaagccg gaagtgctgg tcgggataca cgaggactga
     3841 ttcgtcttca ccaattcaat aaagtagaaa tggtcaaatt ttcggatgta gagcattctt
     3901 acgaagaatt ggaaaaaatg acagctgatg cagaagatat cttgaaaaaa ttgcatttgc
     3961 cttatcgtgt gatggcctta tcaactggag acatgggctt ttctgcagct aaaacttatg
     4021 acttagaagt atggatacct gcacaagata cttatcgtga aatcagttct tgttctaact
     4081 gtgaagattt ccaagcacgc cgcgcaatga tccgttatcg cgataatgat ggaaaaatcc
     4141 actatactca tactctgaat ggttcaggac ttgcagttgg ccgtacagta gctgccattt
     4201 tggaaaacta ccaaaatgaa gatggttctg tcacagttcc agaagcgctc gttccttata
     4261 tggggaatct gaaagttatt aaataaagag gctgtgaaaa agccgcttag tttcgagtat
     4321 taagaaaaat tttgtgaaaa tggctttcca catttttgca taaattggac ttaataccga
     4381 gaaactggct tttgaacacc atttatcgag aggttgtgaa atcagcgaat taacctgagt
     4441 attagagaaa aaaatggaaa aatagtccct catattttac cgtttgttga actaataccg
     4501 agggtcagct gattgaacac cgtttagtgg agaggtcgta agcctacccc ccagctccta
     4561 gttacaagga caaattcaaa aaacagctct tcatatttta tgaatgttgt acttgtgatt
     4621 cggaggtggc aagggaacac tgtttattca aaaagaggct gggacagaag cgtttaactc
     4681 caagaaataa gaagaaattc acgaaaattg cttttcaaat ttttgtgaat ttcttcttat
     4741 ttccgaagga gttgcttcta cttccgccgt ttatacgtgt ttagagcgtg agacaaaagt
     4801 gttctttact tttgtcccac gctctttaat gtttttaaga ttcaactgaa tagtttggtg
     4861 cttcttttgt gatttgtaca tcatgagggt gtgattcttt taatccactg ccgctcattt
     4921 ggataaattg cgcttcatca cgtaattgct gtagattggc tgccccaaca taacccattc
     4981 ctgaacgcaa accgccgatc atttggaaaa taatatctgc aacacttcct ttataagcaa
     5041 cccgaccttc gattccttct ggtactaatt tatttgcttc attgacacta ccttggaagt
     5101 aacggtcttt tgaacctttt tccatcgcgc ctaatgagcc catacctcgg tatgttttga
     5161 atcgacgtcc ttggaagatt tcgaattcac ctggtgattc atctgtccct gccaacatac
     5221 ttcctagcat cactgcatgt ccgccggcag ctaatgcttt gacgatgtca ccagaatatt
     5281 tgatccctcc gtctgcaata atcgctttgc catattgacg agcaactgat gctgcatcat
     5341 aaatagctgt gagctgaggt acacctacac cggctaccac acgtgtcgta caaatcgatc
     5401 ctggtccgat accaactttt acgacatcta cacctgcatc atataaagct tttgtcgctt
     5461 cagccgtcgc aacgtttcct gcaatcaatg ttgcatctgc aaaagttgaa cggatttctt
     5521 gaatttttcg gatcacacct gcactatgtc catgagctgt atcgatgatg attgcatctg
     5581 cccctgcttc taataaagca ttcgcacgct caaatgtatc gcttgttaca ccaacggctg
     5641 ctgctacaag caatcgacca tgttcatctt ttgctgcatt tggaaattcg atcactttct
     5701 cgatgtcttt gatcgtgatc aatccgctta aacgaccttc gttatctacg attggtaatt
     5761 tttcgatttt atgtttttgc aaaatctttt ctgcatcttt tagagaggta cctactgggg
     5821 cagtcactaa gttgtctttt gtcatcacat cagcaatcgg catgtgataa tctgttacaa
     5881 aacgcatgtc gcggtttgta attatcccta ccaattttct gttttcaagt gtttcaacga
     5941 ttggcacacc actgatacga tatttgctca tcaattcttc tgcgtctgct acaagatgct
     6001 gtggcgttaa gaagaacgga tcaatgatta cgccactttc agaacgtttg acttttctta
     6061 cttcatccgc ttgctggctg atcgtcatgt ttttatggat cacacctagt ccgccttgtc
     6121 ttgccatagc aatggccatc ttgctgtcgg taacagtatc catacttgca ctgatgattg
     6181 gaatattcaa cttaatattt ttagctaatt gtacgctcat atccacttcg tttggtaaca
     6241 cgtgactttc tgctggtatc aataagacat catcaaaagt aaatcctttt ttcgtgaact
     6301 ttgtttccca gttggacatt tttagtacca ctcctctaat ttagtttatc tattaaaata
     6361 attgattttt tcatttaagt caatgatcta cttggaatca agttagcttt ctcatagaat
     6421 accaatataa agcgtttaca tctgtgtata ttaaaagaga ttgtaaaaaa gctgtcctgc
     6481 atcaagtaat aagaacagcc aatcaaaaac agcttctcat gtttttgaat tggttgggtt
     6541 tattaccgca gatgcaaact tttgaacacc gtttagtgga gaggctgtga aaaagctgct
     6601 tagtttcgag tagtaagaaa aattttgtga aaatggcttt ccacattttt gcataaattg
     6661 gacttaatac cgagaaactg gcttttgaac accgtttatc gtaaaaaggg actgtgacaa
     6721 gacttttgtc acagtccctt actattattt aactatggat aaacaaaatg aggttcttta
     6781 ctacccctag atatctagca aaatagctga tctttttgct agtttatctt cttgggacgg
     6841 ataaacttcc aataatcccg tattttttct tcaagtagta acggattgct aaagcagttg
     6901 ccccgataat gataactact actggatcta atactggatt gataactggt ggcaatagtg
     6961 ttgtcgcaga aaacagtacg acccaaagaa gtgtcgttcc acctaggata agcaatgtct
     7021 tacccattcc tggtttcttg cttcgatctg ctccgggata ttcatattga tagatgtatt
     7081 tgtacatcat ataaaagacc cagccaccga ttgcagaacc tagaacgagt gtagaaaagc
     7141 cataagctgg cgttgttcca cgtgaaaaca atccggtaat cgcaatcatg atacttaata
     7201 gaccaagcaa cagcaacgta ttatctaacc acatcaataa aggggtggat gaatttttta
     7261 cttctgctgg cttattgatg attgcttccg ttctttcaga gactgtccca aacaattgac
     7321 gggctgttct tccgcctttt tgttctgcaa ctaaagtagg cagaatgtca tgaagggctt
     7381 ttactttttc ttcttcagac aaattcgctg cttctaaaga ttttttcaaa tcaaaaatgt
     7441 actgttgatt tcttttggtt aattttgttt ctaaactatt gttttctttt acgattgctc
     7501 gtaattgttc tggttccatt atctaatagt cctccttagc cgttcctttt ctcaacggtc
     7561 gtcacaaaag acattctacc atattctaca gctagtttga tagccctttt acacattaaa
     7621 gcggaataac attacgtcgc cgtcttgtac gacataatct tttccttcta atcgaacacg
     7681 tccagcttct tttgctgcat gcatgtttcc gtaatgatcc aagtcttcaa aagagacagt
     7741 ttctgcacgg ataaatccgc gttcgaaatc tgaatggatg attcctgctg cttgtggtgc
     7801 tttgattcct tttttgaatg tccaagcacg tacttcttgt tccccagcag taaagtaagt
     7861 agctaagcct aacaaatcat aagcagcacg gatcaactga tccaaacctg attcttcgat
     7921 tcctaaagct tctaaaaatt ccgctttgtc ttcttcatct aattctgcga tttcttcttc
     7981 tgcacgagca ctgaccacga tcacttctgc attttcttct gcagcaaagt tgcgcacttc
     8041 ttgtacataa tgattcgcgt ctgcatctgc tacgtcatct tctgagacat tggctacata
     8101 aagaattggt tttgtcgtca ataaaaatag tgatttaacg attttttgtt cttcttcagt
     8161 aaattcgatc gttcgggcag attttccttc ttccagtaca ggtttgattt tatccagtac
     8221 agctagttct gccactgcat ctttatcttt ggttttagca acttttgcta cacgagtata
     8281 gcgtttgttg atagattcta agtctgctaa cactagttcc aagttgatcg tatcaatatc
     8341 ttctagtgga tcaacacgtc cttctacgtg agtaatatta tcatcatcaa aacagcgaac
     8401 aacgtgacaa atagcgtcta cttggcggat atggcttaag aattgatttc ccaaaccttc
     8461 tcctttactt gcgcctttta cgattccagc aatatctgta aattcaaaag tcgtcggaac
     8521 agtttttttc ggatgtacaa gttctgttaa gcgttgcaaa cgccagtcag gtacttctac
     8581 catccctacg ttggggtcga tcgtcgcaaa gggatagttt gctgcttctg ctcctgcttt
     8641 tgtgatcgca ttaaacaaag ttgattttcc tacgttgggc aacccaacaa ttccagcagt
     8701 caatgccata aatttattca ctctttctct gcattttttt caattacttt ttttaatttc
     8761 ttttcaaaat ctcgacgggt catcatgacg atatgtccgc aattcataca tctgattttg
     8821 atatctgcgc ccattcgaat gacttcccag cgattcgtct ggcaagcgtg aggttttttc
     8881 atttcaacga tatcgtgcaa gtcgtacata aaaatagcct cctttttgtt tattcttcat
     8941 caaattgaat attcaagata tcaagaattc gagtcaaatc tttttgagaa agatattcaa
     9001 tctcgatctt acctttccca tttttttctt ggatagctac acttgtacca aatttatcca
     9061 tcaaacgatc ttcgctttct cggatataat atggtttttc ctttgctagc cttgggattt
     9121 ttttcttttc ttttccatca ttttgattta actcagaaac aagctgttcc agttggcgga
     9181 cagttaaatt ttcagttact gcacgattgg ctaatttcaa gatcaatgtt ttatttttta
     9241 aacctaacag cgtacgggct tgtcccatag ataaacgctg atcttgtacc atttccttga
     9301 caagatccgg taaagaaagc aagcgcaaat aattggcgat ataaggtctg ctctttccta
     9361 aacgactagc tacttctgct tgtgttagtt tcaggttttt catcagcatc tcatatgctt
     9421 ctgcttcttc taacggattc agatcttctc gctgcaagtt ttccagcact gctacttgca
     9481 tcatcgcttc ttcgtcaaag tctctaacga tagcagggat cgtttctttt tcagctagtt
     9541 tggacgctcg aaaacgtcgc tcccctgcaa taatctcata tccttttact gcggaacggc
     9601 gtacgatgat gggttgaaag acacctgatt gttcaataga attagctagt tcctgcaaag
     9661 atacttcttc aaatgtttta cggggctgat acggatttgg tcgcagctca ttcaatggta
     9721 gctggacaac ggtatcatct tttacatcca ccgtctctaa gttttctaaa tcttgaaaca
     9781 gtgcatcgat tcctcggcct aatcctttac ttttcttcac gacttaccac ttcctttgcc
     9841 aatgcttggt agacttcagc tcctcgagaa cgtggatcgt agtcgatgat cggttttcca
     9901 tgactaggtg cttctgataa acgaatattt cttggaatga tcgtttcgta aactttttcg
     9961 cggaagtatt tacgtacttc ttctacgact tcatttccca gatttgttcg tgcatcatac
    10021 attgtcagta agactccctc gatctctaat tctggattaa agtgtttttg gactaaacga
    10081 accgtattca gtaattggct taatccttcc aatgcgtaat actcacactg aacaggtatc
    10141 aaaatcgaat cacttgctgt aaatgaattg attgtcagat ggccaagaga aggcgggcaa
    10201 tcgatcaaaa tataatcata ctgactgctt acttctgcta aagatccttt taatcttgat
    10261 tctcttgcca tcattgacgt caattcgatc tctgctcctg ctaattggag agtcgcaggc
    10321 acaatactca aattttcgtg ttcagtgatc aaagttgcct catcaattgg caattcattg
    10381 actagaacat catagatgtc tcttgtcaca tcaggttttc tgatcccgac accactggta
    10441 gcatttcctt gtgcatccat atccactagc aatacttttt tgccaaggct agcaagacaa
    10501 gcacctagat tcaccgtcgt cgttgttttg ccgacgccac ctttttggtt cgcaacagat
    10561 attatttgtg ccatctcttc tcctcctatt tgattggctg cttattaggc agtccgggct
    10621 ttcttgggta tttctttggg gttggtttct ttttttgaat aacgatgata tgccgttgat
    10681 cagagacatt cggcaaggta accgcctctt ctttgaggaa tttaccacct aataaagcaa
    10741 tcgcttgttt tgcttctgtc aattcctctt cactttttgc tgctttcaat gcataaaaat
    10801 agccttcttg tttagccaag ggcaaacaca attccgctaa cacattcaaa cgagcaaccg
    10861 cacgagcagt gacaaggtca aatgatgcac gaaagtgagg attttgccca aatgtttctg
    10921 cccggtcatg atataaggaa gcatcgattc ctaataatcg ggttaactca gataagaagg
    10981 ttattcgttt attcagagaa tcaacgatcg ttatctgcag ttctggaaag gcaattttta
    11041 aaggtatgct aggaaaccct gcccccgaac caacatcgca taaagataaa ggttgcgtaa
    11101 agtctacttc aaatgctaat gtaagtgaat cgtaaaaatg cttcagatat acgtcttttt
    11161 catccgtaat agctgtaagg ttcatctttt cgttccattc gactaatgtc cgataataaa
    11221 tagcgaattg attcatttga tgatcggtaa gctctatccc tttttctgcc aaggattggc
    11281 gaaattcttc tggtatcata aatattcctt tcattgtgaa acagcaattg tttcacagat
    11341 tctctcccta ctttaacgca aaatctctag acatgcaatc cttccatatg gattcttaaa
    11401 aatttgaaaa gtaagaaaag ccgatagact ttttctttct agtatgactc ataaaatata
    11461 cacagaagag agaactagct ttgagcaatt tctgcaaaaa ctagttctct cttctattta
    11521 ttattacgta ttacgctggt tcactgactt tcgcaatctt cccttgttcg atatagacca
    11581 ttaggatact taggtctgca gggtttacgc cactgattcg gctagcttgg gcaattgttt
    11641 ctggttggat tttctgcaat ttttgttttg cttctgttgc taatccgttg attgctgcgt
    11701 agtcgatgtt ttctggaatc tttttcgctt ccatgcgttt taatttttct actttttcca
    11761 tggctttttt gatgtagcct tcatatttga tttggatttc tacttgttcg atttcttttc
    11821 gtgtcaattc ttcattttct ggaataaacc gtagaagttc tgcataagta atctcaggac
    11881 gtcttaaaaa gtcgcttgct agtacaccat cttttaatgg tgccgcatta atcgttgcta
    11941 aaaagtcttg gacttcttct gttggtttga ttcgtacatt catcaaacgt ttgatttctt
    12001 gttcaactgc ttcttttttc ttcaaataat tcttgtattg atcttctttt actaagccta
    12061 cacggtgacc catttctgtt aatcgcaaat ctgcattatc atgacgtaaa agcagacggt
    12121 attcagcacg tgaagtcagc aaacgataag gttcgttcgt tccttttgtt accaaatcat
    12181 cgatcatgac accgatgtaa ccgtcacttc gtttgatcac taaaggttct tttccctgaa
    12241 ctttcaaagc tgcattgata ccggcaatca gcccttgtcc agccgcttct tcataaccgc
    12301 ttgtaccatt tgtttgtcca gctgtataaa gattttcaac gactttagtt tctaatgtcg
    12361 gacggagctg gtgtggctct actacgtcat attcgatagc atatcctgta cgcatcattt
    12421 ctactttttc taatccagca atagaatgaa gcatgttgac ttgaacatcc tctggtaaag
    12481 aagtagataa accttgaaca tagacttctt ccgtatttaa gccttctggt tccaaaaata
    12541 attgatgacg tggtttgtct gcaaaacgca cgatcttatc ttcgatggat ggacaatagc
    12601 gagcgcctac cccttcaacg atccctgtaa acattggggc acgatgtaag ttgtctcgaa
    12661 taatttggtg agtcgtctca cctgtatagg tcagccagca agattcctga tctagtttat
    12721 aggcactatc tggtgtgctg aagctaaaat gattcggctc tttgtcacca ggctgctctt
    12781 ctgtaacaga atagtcgatc gtacttgatt ttactcgagg cggtgttcct gttttgaacc
    12841 gttcgatagc aaagccaagt tcttttagat gattcgctag tccaatagaa ggttgagagt
    12901 tattcggacc tgatgaatat ttcaattcac cgataatgat ttctccgcga agtgctgttc
    12961 cggctgtaat aacaactgct ttggcccggt agctcgctcc tgtggacgtc actactccat
    13021 gacaaacacc atcttcgacg atcagttctt cgacgattcc ttgtcttagc gtcaaatttg
    13081 gttctttttc gatcgtatgt ttcatttctg ttgaataagc atgtttgtct gcttgtgctc
    13141 gcaatgctcg gacagctggg ccttttcctg tgttcaacat acgcatttgg atataggttt
    13201 tatcgatatt cttacccatt tctccgccta acgcatcgat ttctcgaacg acaacgcctt
    13261 tagctggtcc gcctacagaa ggattacatg gcatgaatgc taccatgtcc aaatttattg
    13321 tcagtaataa tgtttttgat cccatacgtg cagcagcaag tgcagcttct gaaccggcgt
    13381 gtcctgcgcc aacaacgatc acgtcatacg catctgcttc ataatgttcc aatcgtttgt
    13441 tcctcctttt attttcctaa acaaaattga ctgaataatt gagtgattag ctcatcttgt
    13501 acactgtcgc cgacaacttc tcctagatag tcccagcaac gcgtcatatc tatttgaacg
    13561 agatccacag gcattcctga atcaatacct gcaatgactt cttcaagtga gagggaagct
    13621 ttttctaaca acgcgatatg gcgggtatta gaaacataag tagcgtctct ttctcctgtt
    13681 tctccgctga agaataaatc agaaatagct gattccaaac gatctagtcc gtcgttttta
    13741 gctacggaaa ttgaaaaaac tggttcattt tcgatcaatt tcttcaattt ttcttgttcc
    13801 agctgtgctg gcaaatctgt tttatttaga agaatgatcc gtttcaatcc acttgtcgct
    13861 tccaataatt gttcatcttc tgctgtcagt ggttcgcttt ggtttagaac aagtaagatc
    13921 aagtctgctt ctgctaatgc ttttcggctt ctttcgaccc cgatccgttc caccacatct
    13981 tctgtttccc gaattccagc tgtatcgatt agcttgagcg gtaccccccg aacattgaca
    14041 tactcttcga ttacatctcg agtcgttcct gcaatatccg taacgattgc tttttcttct
    14101 cttaacaaat ggtttaacaa acttgatttg ccgacatttg gccggccgat gattgccgta
    14161 cttaaccctt cccgcagaac cttcccttgc ttggatgtag caagtagcgc ttggattctt
    14221 tgttggatca tctgcgcttt ttcaagcaat aacttcgtag tcaattcttc gacatcatca
    14281 tattctggat aatcaatatt tacttctact tgtgctaatg tctctaaaat ctcttgtctc
    14341 aatgagcgga tcaaagcaga cagattgccg tctaactgat taagagctag tcccattgct
    14401 ttgtctgttt ttgcccgaat caaatccatc acagcttctg cctgtgaaag gtcaacacga
    14461 ccattcaaga atgctcgttt tgtgaattcg cctggctcag ctaatcttgc accttctctt
    14521 aacaatagct gcaaaatttg attgactaca acgatcccac cgtgacaatt gatttctact
    14581 acatcttccc gcgtaaatgt ctttggtgct ctcatcacgg agaccatgac ttcatcgaca
    14641 agctgattgc tcttgggatc aacgatatgt ccataatgga tcgtatgact tggtacttct
    14701 gataatcgtt tgtttccaga ttgataaact ttatctgcta gttgcacagc ttgatcgcca
    14761 cttaaacgaa cgatactgat tgcaccttct ccaggtgggg tagaaattgc cgcaatcgta
    14821 tcaaattcta aagtaatttc agccattttt tcacttcctt tttcattttg cgcacaaaaa
    14881 aagtgcccac tccacccttt atgcacaata aacggtgaac ttcgcacttt gactgcttgt
    14941 tcttgattaa attctggtca tagattatca cacttgctat aaggaatcaa gtgtttaaaa
    15001 caattagatg aagttgagcc tgttctgctt ccattacctt atatttaatt gtccttggat
    15061 gtctctttgc gttctttggt ttattcgaag agaagatact gtataaacaa ggctttatct
    15121 ttcttaaaaa aaacggtaca ctaaatggta gcgctatcta aactatacac ttttgaaagg
    15181 agaaaatatg tgagcccgtt cagatctgct gcattggaag aagaaagtga ccctcggatc
    15241 aacgatgtcg ttttatctac agggaatatc aaccagaaat atatcgtccg cgatatcgtt
    15301 tttgttgtgg aatgcttaga agctgatttg tttgacccat cttttcccaa agatgacctt
    15361 ttcttaacaa cgaagaggaa attaaagacg aaggtacttg aatatggtgc gaatgcagta
    15421 atcaactgtc attttgagta tcagcaaaaa aaacgcgacg gaaagtattt tctggaactt
    15481 tttgcttatg gaacagtgat ccaatttatc caaacaacga ttggttaaat gaaacagaca
    15541 aaaaaagcgg atcaaaactg aagacagttt cgatccgctt ttttctatca aagttagtga
    15601 ctacttcatc gtatactctg ataagaatga tttctagtaa aatatacttg gtttgaaaaa
    15661 ctttgtcaac gtgatttatt caaaaagtaa tggaatcaat aatatttttt agcaggttct
    15721 actactaaat aacgataagg ttcctcacct tccgaatgtg tttttacatg ttcatctttg
    15781 cttaatgcag catggatttg tttacgttca aatgcaggca ttggttctaa gaaaacaggc
    15841 tgccctgtcc gttttacttt ttcagccgtg cgatcagcta aacgctgaat gatctcttgg
    15901 cgcttttcac ggtaattgcc tacattgact actacagaca gcttatttct tgctaaacga
    15961 tggatgaaga cttgtgccag atattgcaat gcattcagtg tttttccatg tttcccaatc
    16021 agtatgcctt gcttttgtgt ttctaaatgg aaaacaacca tattatttga ttctctttcc
    16081 attttgacaa gagctggagc atcaagctgt tttgaaattt cagtaagata aactgccaat
    16141 tccgttaaag ctgcttcatc acctagctca cttacttctt ctgttttttc ttcaagaatc
    16201 gtttcgttga ctacctcgat ctcagctgtt ggttcttctt ccaaaatttc ttctacagtc
    16261 tgttctactg tttcagaaac tttttcgctg atacttggct ggatcgaaag ccgtgcattc
    16321 tttcgaccca ttcctaggaa accttttttt ccttcttcca gtatttcgat ttcgacttgg
    16381 tctttggcca aacccaaatc agccagacct agttggacag cttcgtctat tgttgcagct
    16441 tcataaatcg gcattagcat tacctcccct attatttccg ttttttctta ggattcattg
    16501 ctttcttaag agcacgttct ctttcgcgga ttctccgtgc ttcttcttca cgctcttttc
    16561 gaattttgaa agggttgttg atcagcagcg tttgtacaac ttggaaggca ttggaaacta
    16621 cccagtataa tgaaagaccg ctggctaaat tgacacccat cactaaaatc attacaggca
    16681 tcacgaaatt catgatcttc attgatgcat tcgattcaat ttgactcatg ctagataaat
    16741 acgtacttgc aaaagtaaag attgctgcta aaatcggcaa aataaatgtt ggatccgcgt
    16801 tccctaagtt caaccataag aaatgccctt gtttcaactc tggtacacgt gaaatagatt
    16861 gccataacgc catcaagatt ggcatttgta ctaataaagg aagacaacca gcatatggat
    16921 tgacgccatt ttctgcatat aaacgctgct gctcttctct taacttactt tgtgtttccg
    16981 gatctcttga actatattgt tgctgcagtg cttttaattt cggttgtaat tcttgcgttt
    17041 tacgcatgct ctttgtttgg aaatgcatca acggcaatag gatcacgcgg atgatcagtg
    17101 taaataaaat gatccctatc cctgcattac caaatgacaa cgccttgatc gcctcagcaa
    17161 agtaataaac aatataacga tcccaaattc ctgtactctg tgcgctgact tccccagttc
    17221 cgcaaccgga taagacgatg accaaactaa cgataccggc catcaaaagt aaacgtttgt
    17281 atttcttcac ttactctttt cctctctgtc gattattttt gcaagtttta agacgtggac
    17341 taaattggag cgaacctcat cataagtcaa ccccttcaca cttggtctag caatcacaat
    17401 aaaatccaac tccggatcaa tttcttcttt tatagaataa actgctgctc ggatttttcg
    17461 tttgacttca ttgcggttta ccgcgttgcc gacctttttt cctacagata aaccaactcg
    17521 aaaatgaggc tgtcccggtt tttccaaacg gtaaacgacg aatttgcggt tagcaaaaga
    17581 atctcccgta tggaacacgg cttgaaactc tcgttctttt tttactcgat acgcttttct
    17641 cattagtttt ctttcctttt ctatctctca cttacgctca taatcatacc ataattacga
    17701 ttgtcctttc atcatttccc taaaaaagag tataaaaaaa accactgaaa ccccagtggc
    17761 ctaagctgaa agaacttttc ttcctttgcg acgacggcta gctaacacac gacgtccatt
    17821 tttagtactc atacgtttac ggaatccgtg aactttttga cgtttacgtt tatttggttg
    17881 gtatgttctt ttcatatatt ccacctccaa aatgttctta tctattttat aaacacagac
    17941 atactttgat agtataacga caaagtagtg attttgtcaa tataaaatag aagatcgatt
    18001 gttaaaactt atccacaaga ttattttttt ctatgggaat cctatgtgga aaaagttatg
    18061 cacagggatt atccacagat aataaaaggc tggttttaca cagaaaacac acgtgtaaaa
    18121 aaagtaatcc acaatcaggc gatttcctgt gtattccgtc tcctaactat tggtatatct
    18181 gtatttttta tccacagacg caagaggaaa tctattggtt tttacgagtt ttccacctgt
    18241 gcattagtgg tgtggaaaac tttttttgac aactgtgttt ttctcttttt tctttttgtc
    18301 gattgtgtgg ataattgtaa ttaaaaaatt tttttcttcg gtttctgtgg aaaactattg
    18361 aaaaaaatgc taaattagta ctagttattc actttttaat gaaggaggag gccttatatg
    18421 gtatccctcg atgctttatg gaatgaatta aaagcaacat accaaaagga tttatcgcct
    18481 gctagctata atacatggat cgaaacagcg aaccctcgaa cccttgatca aaaccagctc
    18541 gttgttgagg ttcctagcaa gattcataaa gaatattggg aaaaaaacct ggcgacaaaa
    18601 atcgttgaag tcggttatat gttatcagga aatgagatta tccctcgctt tattactggc
    18661 gaagaagcag agcaagaaga agttatagaa gaaaaaaatc caaaagttgt ggcacctagt
    18721 ccgctaaaaa aagccatgct gaaccctaaa tatacctttg atacgtttgt cattggtaaa
    18781 ggaaaccaga tggctcatgc agcagcgctc gttgtagcag aagatccagg ttctatttat
    18841 aacccgctct tcttttatgg aggcgtggga cttggtaaga ctcacttgat gcatgcaatt
    18901 ggtcatcaaa tgctgcaaag tcagcctaat gccaaagtaa aatatgtaag cagtgaaact
    18961 tttgctaatg atttcatcaa ttcgatccaa aacaaaacag cagaagagtt ccgtcaagaa
    19021 tatcgaaatg ttgatttact gctagtggat gacattcaat tttttgcaga aaaagaagct
    19081 acgcaagaag agtttttcca tactttcaat gccttgtaca atgaagggaa acaaatcgta
    19141 ctaaccagtg atcggttgcc aaacgagatt ccgaaactgc aagaacgcct tgtttctcgc
    19201 tttgcatggg ggctgtctgt tgatattaca ccgccggatc ttgaaacaag aacagcgatt
    19261 ttacgtaaaa aagcggcggc tgaacgtcta gagatcccag atgacacact aagctacatc
    19321 gcaggacaaa ttgattctaa cattcgtgaa ttagaaggtg cgcttgttcg agtgcaagct
    19381 tttgctgcga tgaatagtga agatatttcg actagtctag ctgcagacgc actgaaaacg
    19441 ttaaaatcag gaaaaggaca tcctcaattg tcaatcctgc agatccaaga agaagtggca
    19501 aagtattatc acatccaatt gaaagatctc aaaggaaaga aacgcgtcaa atctattgtt
    19561 gttcctagac aaatcgctat gtatttggca cgtgagctca cagataattc tttaccgaaa
    19621 atcggagctg aattcggtgg caaggatcat acaacggtta tccatgctca tgaaaaaatc
    19681 cagcagctga tggattctag tgtcagtatg caaaatgaag tatcagaaat caaaaacttt
    19741 ttactaaatt aatttgtcga ttctatcaac tgaaaatagc atgtggataa aagaaaaaaa
    19801 cgttcaaaag ttatacacac tttttccaca gctgtttttt cgtttctctc ttacgttttt
    19861 tgagttttcc acagaatcaa catgccctat tacttttatt attcttttta actaataata
    19921 aataaacaaa cattcaaagg agatacatca tgaaagttac tttaaaccga gctagcttta
    19981 tgcaggaatt gcaaactgtt caacgagcta tttcaagcaa aaccacgatc cctattttga
    20041 caggtgtaaa aatcacactg acacaagaag gtttgacttt gacggggagc aacgctgata
    20101 tatcaattga aacttttttg tctgttgaaa acgaaaaagc aaatatgcaa atcgaatcta
    20161 ctggttccat tgttttacaa gcacgtttct ttagcgaaat cattcggaga cttcctgaag
    20221 aaacatttac tttagaagtt ttagaaaata aacaagtagc gatcacttct ggaaaagcga
    20281 attttatcgt aaatggatta gatgcagata actatcctca tcttcctgtt gtcgaaagcc
    20341 ataaccagat gaaattacct gtacacgtat tgactaaact aatcaacgaa acagtttttg
    20401 ctgtctcaca acatgagagt cgtccaatct tgacaggtgt gcatttcatt ttatctgata
    20461 attctttatt agctgtagct actgattctc accgtctaag tcaacgcgtg attccagtag
    20521 aacaagcggc tgatcatttt gatattgtta ttcctggaaa aagtttgatc gaattatctc
    20581 gctcattaac aaatgaagaa gaaatcgtcg aaatcagcat tatggaaaac caagtgttgt
    20641 tcaaaacaga aacgatgtat ttctattccc gtttgctaga aggaaactat ccagatacca
    20701 atcgtttgat tccttcaagt tttaatacag aggttgaatt ttctgttcct agctttttag
    20761 cggcgatcga acgggcttct ttactttctc atgaaggccg taacaacatc gttcgtttat
    20821 ctattcgtcc agatgcggtt gttttatacg gaaattcgcc agaaatcggg aaagtagaag
    20881 aaagcttgag ttatacagca agcagtggcg atccattaga tatttctttc aatccggatt
    20941 atatgaaagc agcgttgcgt gcatttggag atatgagcat caaagtgaaa tttatctctg
    21001 ctattcgtcc atttacattg gaaccaacgg aagatggcgt tcaatttatt cagctgatta
    21061 ctcctgtacg tacaaattaa caatgatttt caatgttctt gaaaatttaa ttgaaaagaa
    21121 atagaaaaaa taaaatttta aacagaaggc cctaaaatct cttttaaggc tttctgttta
    21181 tttttgttta aatcaccttt tttagattaa atcgtcttat atggaaaaat atatggataa
    21241 atttgtttta ttgcgaaaaa aaaggtataa tagagtatac ttttaataat gaaaatgagg
    21301 gatgggcatt gaaacaacaa gtcattctaa atacggaatt catgacgttg ggccaaatgt
    21361 tgaaagaagt cacagttatc ggtagtggcg gacaagcaaa atggtatttg gcagaaaaca
    21421 ctgtgttagt cgatggcgaa ccagaaaatc gtcgtggacg caaactttat cccggcatga
    21481 tggttgaagt tccagaagta ggaacttttt ttatggtaaa aaaaggaaac gacgataatg
    21541 aggctgaata agctgtattt aaaaaattat cgaaattacg aagagctgaa catcgaattt
    21601 tccaagaacc tcgtcatctt tttaggagaa aatgcgcaag gaaaaacgaa tcttttggaa
    21661 agtatctacg tattagctat gacgcgaagt catcggacaa gtagtgagca ggaattgatt
    21721 ggctggactg acgatcaggc gatgattcaa ggagagatca caaaaggttc atccactctt
    21781 ccattagaaa tcttattatc taaaaaaggc cgaaaaacca agatcaacca tatcgaacag
    21841 aaaaagttaa gtacttacgt gggacaaatg aatgtcattt tatttgcacc agaagatctt
    21901 tctttagtaa aaggcagccc gcagaccagg cggaagtttt tagatatgga attaggccag
    21961 atcaatccaa tctatcttta tgatcttgtc caataccaag caattttgaa acaaagaaac
    22021 cagtacttga agcaattgaa tgaaaaaaaa caaactgatt tgctttattt ggatattttg
    22081 tccgaacaac tagcagcgtt tggcagcaaa gtattgaaag caagagcaca gttcgtcaag
    22141 cgattggagt tttgggctaa ttctttgcat cagcaaatca cccatcaaaa agagcagctg
    22201 gaaatcgagt atctcaccgc agtcgattct ttagaaacac atacgcaaga gcaaatccaa
    22261 gaacaatttc tcgcactttt gaaccaaaat aaaaagaaag acctttttcg gggaacaacg
    22321 acagttggtc ctcatcgtga cgatctttcc ttttttatta atcagaaaaa tgtgcagact
    22381 tatggatcgc aaggacagca aagaacaact gcactaagtg tcaaattagc agaaatcgat
    22441 ttgattaaag aagagacagg ggaatatcca atccttttgt tagatgatgt gatgagcgag
    22501 ctggatgata atcgtcaact ccatctgcta gaaacaatcg aaggaaaagt tcaaacgttc
    22561 ttaacaacaa cgacacttga ccatgtaaaa aataaaatga ctgttgaacc tgagattttt
    22621 tatgttcaac aagggaaact aaaaggagaa gaaactgaat gacagaagaa agaagtttag
    22681 tagaacgcgc taaagagtat gatgccagtc agattcaagt acttgaagga cttgaagccg
    22741 ttcgtaaacg acctggcatg tatatcggtt cgactagttc tgagggtctg catcaccttg
    22801 tttgggaaat tgtcgataat tcgatcgatg aagtattagc aggttttgca acgaaaatcc
    22861 atgtgattat tgaaaaagac aacagtatca ccgttattga cgacggtcgg gggatacctg
    22921 tagatatcca ggcaaaaact ggacgtcctg cagttgaaac ggtctttact gttttacatg
    22981 ctggaggaaa attcggcggt ggtgggtaca aagtttctgg tggacttcac ggagtaggat
    23041 cttctgttgt taacgcgctt tctacacagc ttgatgtcaa agtatacaaa gaaggaaatg
    23101 tgtactatca agaatatcgt cgtggagctg tagtggacga cttaaagatt atcgaacaaa
    23161 cggatcgcca tggaacaacg gttcacttta cgccagaccc tgaaattttt acagagacaa
    23221 ctgagtttga tttttcaaaa ttggctaccc ggatccgtga acttgctttc ttgaaccgcg
    23281 ggatgcgtat atcgattgaa gacaaacgag aagaagaacc agtcatcaat gaataccatt
    23341 atgacggcgg gattaaaagt tatgtcgaat acttgaatgc aaacaaaacc gtgatttttc
    23401 cagaacctgt atatttggaa ggtgaacagc aagatatcgc agttgaagtc tctatgcaat
    23461 atacagacgg ctaccattcc aatatcatga gttttgccaa caatatccat acgtatgaag
    23521 gcggaacaca tgaatcagga ttcaagactg ctttaactcg tgtgataaat gattatgccc
    23581 gaaaacaaaa gctgatgaaa gaaaatgacg acaacttgac cggtgaagac gtgcgagaag
    23641 gattgacagc tgttatttct atcaagcatc ctgaccctca attcgaagga caaacaaaaa
    23701 caaaattggg caattccgaa gtacggacag tcactgatcg gttatttagc gaacatttca
    23761 tgaaattctt gctggaaaac ccaagtgtgg gccgtcaaat tgttgaaaaa ggattactag
    23821 cttccagagc tcgtctagca gcgaaacgtg cgcgtgaagt aacgagacgt aaaggtgctt
    23881 tagagattag taatctgcca ggaaaattag cggactgctc tagcaacgat cctgaaaaat
    23941 gcgaattgtt catcgtcgaa ggagattcgg ccggcggatc agctaagcaa ggtcgtaatc
    24001 gagagtttca agccatcttg cctattcgtg ggaaaatctt gaatgttgaa aaagcaagca
    24061 tggacaagat cttggcaaat gaagagatcc ggtctttatt tactgctatg ggtacagggt
    24121 ttggagaaga ttttgatgta tcgaaagctc gctaccacaa attagttatc atgactgatg
    24181 ccgatgtcga cggcgcgcat atccgtacat tgctgctgac tcttttttat cgttacatgc
    24241 gtcctattgt tgaagctgga tacgtctata ttgctcagcc acctttatac ggggtaaaac
    24301 aagggaagaa tattacgtat gtacaaccag gaaaaaatgc agaagaagag ttgaaacaag
    24361 tcgttgcttc acttcctgcc tcaccaaaac caagcgttca gcgttataaa ggacttggag
    24421 aaatggatga tcatcaacta tgggaaacaa ctatggaccc aagcaatcgg atgatggccc
    24481 gcgtcagtgt ggacgatgct attgcagcag atcagatatt tgaaatgttg atgggggatc
    24541 gagtagaacc ccgtcgtgca ttcatcgagg aaaatgcaca ctatgtgaag aacttagata
    24601 tttaatcatg aaggaggaaa aagaatgagt gaagaaatca gagaaaacat ccatgatgtc
    24661 aatctaacca gcgaaatgaa agactccttc atcgattatg cgatgagtgt tattgtcgca
    24721 cgtgcacttc ctgatgtcag agatggtctg aaacccgttc atcgccgtat tttatacggc
    24781 atgaacgaat taggtgtaac accggataaa gcccataaaa aatctgccag aatcgtcgga
    24841 gatgtcatgg gtaaatacca tcctcatgga gactatgcga tctatgagtc aatggtacgg
    24901 atggcacagc cattcagcta ccgttatatg ctagtggatg gtcatggaaa ctttggttct
    24961 gttgacggtg acggtgccgc cgctatgcgt tataccgaag cacggatgag caaaatcgct
    25021 acagaaatgc tgcgtgatat caataagaac actgttgatt tccaaagcaa ctatgatgat
    25081 acagaaaaag aaccagttgt actacctgct cgcttcccga atcttttagt gaacggaaca
    25141 acggggatcg ccgtaggtat ggccacgaat atcccacctc ataacttgtc tgaggtagta
    25201 gcggctatcg atttgctgat ggataatcct gatgtgacga ccaatgaatt gatggaagta
    25261 ttacctggac cagattttcc aacaggtggt ttggttatgg gaaaatcagg aatccgaaga
    25321 gcgtatgaaa caggtaaggg ttctattacc gtacgtgcaa aagttgagat tactgagatg
    25381 ccaaatggta aagaacggat catcgtgaca gaattgcctt atatggtcaa taaagcaaaa
    25441 ttgatcgaac ggatttctga actgcacaga gacaagcgta tcgaagggat cacagatttg
    25501 cgggacgaat cttcccgtga aggtatgcgg atcgtcattg acatccgtcg tgacgccagc
    25561 gcatctgtta tcttgaataa cttatataaa ttgacatcct tgcaaaattc atttggattc
    25621 aatatgttgg cgatcgaaaa aggtgtgccg aaagttttga gcttgaaaca aattcttgaa
    25681 aactatatcg aacatcagcg cgaagtcatc acaagacgga cagtctttga aaaagaaaaa
    25741 gcagaagcaa gggcacacat tttagaaggt ttgcgtattg ctttggatca tatcgatgaa
    25801 atcattgcga ttatccgcgg gtctaaatca gatgacgaag caaaagcgac gatgatcgaa
    25861 cggttcgatt tatccgatcg ccagtctcaa gctattttag atatgcgttt acgccgattg
    25921 accggtttgg aacgggaaaa aatcgaaaat gaataccaag aactcttaaa actgattgaa
    25981 gatttaactg acattctggc aagaccagaa cgtgttacag aaatcatcaa gaatgaatta
    26041 gcagacttga atcaacgatt tggtgataaa cgacgcacag aattactagt cggtgaggtc
    26101 ttaagtctgg aagatgaaga tttaatcgaa gaagaagaaa tcgttattac attgacaaac
    26161 aatggttaca tcaaacgttt ggcaaataat gaattcagag ctcaacgaag gggtggacgt
    26221 ggtgtccaag gaatgggtat ccacaatgac gacttcgtca aaaatctggt ttcttgttct
    26281 acccatgata cattgttatt ctttacgaat aacggaaaag tgtatcgggc aaaaggatac
    26341 gaaattccag aatacgggcg cacagccaaa ggaataccaa ttatcaattt actaggtatc
    26401 gattcgagtg aaagcatcca ggcaatcatt gcggtgacgg gagaagcaga agaaggccac
    26461 tatctcttct ttacgacgcg tcaaggtaca gtaaaacgta cttctgtcac tgcttttgct
    26521 aacatccgaa gtaatggtct gatcgcaatt ggtttgaaag aagacgatga gctcgtcaat
    26581 gtgctactga cagatggtca atctaatatc attattggaa cacataacgg ctactctgtc
    26641 actttcaaag aagaagcagt ccgcgatatg ggacgtacag cttccggggt tagaggaata
    26701 cgcctgcgtg aggaagatta tgtcgttggg gcagccttaa tgaaggaaga tcaagaagta
    26761 ttagtgatca cagaaaaagg ttacggaaaa cggacaaaag tatcggaata tccagtgaaa
    26821 ggccgcggag gtaaagggat caaaacggcg aacatcactg aaaaaaatgg tccactagct
    26881 ggattgacca ctgtttctgg agatgaagac atcatgctga ttacagataa aggtgtcatt
    26941 atccgtttca acgtatcgac tgtttctcaa actggacgtt caacattagg cgtacgtttg
    27001 atgaagatgg aagctgatac gaaagttgtc acgatggcag cagtcgaacc agaagctgca
    27061 gaacaaacag ttgaagaaca aggatcagaa gaatagccat caagactaat tgtgtaagct
    27121 agcaagaatg accgattaaa aaatctggtt attcctgctg gcttttttga ttagttgaat
    27181 ttctcttaaa atattcgaaa ctgttcattc tgtattgctt ttgaccaaaa tagagtgtat
    27241 aatcagagct tgtgagtagt ctaattaatt agataactct ccttgctctt aggaacctaa
    27301 gagccgaaag tccacaggga ggtgaatatc aatggaaaac acgaaatatg aaatcatgta
    27361 cattattcgt ccaaacattg atgaagaagc aaaaactgct ttaatcgaac gtttcgatgc
    27421 aatcttgaaa gataacggag cagaagttat cgaatcaaaa gattgggaaa aacgccgttt
    27481 cgcttatgaa atgaacggtt accgtgaagg tatctatcac atcgttaaag tatcttctcc
    27541 atcatcagca aatgctgtca atgaatttga ccgtcttgct aaaatcaacg acgatatcat
    27601 tcgtcacatg attgttaaag aagaagctta attgttgttt catgtgaaac aatagaaaac
    27661 gatgagagga gatgactatt ttgattaata atgttgtatt agttggacgt ctgacgaaag
    27721 atccagattt gcgttacaca gcaagtggta cggcagtcgc aacatttact ttggctgtga
    27781 atcgtaattt tacaaaccaa agcggcaatc gcgaggctga ttttatcaac tgtgtgattt
    27841 ggcgcaaatc agcagaaact ttagcaaact atgctcgtaa aggaacactt ttaggtgtta
    27901 ctggacgtat ccaaactcgt tcttatgata atcagcaagg acaacgtgta tacgtgacag
    27961 aagtagtagc tgacaacttc caattgctgg aaagtcgttc tgcatctgaa aatcgccaac
    28021 aaagcggcgg attccaaagt tctggtcaat cagctggcgg atttggcgga aacaataact
    28081 ctaatcaaac atctcaatca tccaacggta tgcctgattt cgaccgtgat acttctgacc
    28141 cattcggctc aagttcaacg atcgacattt cagacgatga tttaccattc taaacgaatt
    28201 tgataggagg gaaatagaat ggcacaacaa agaagaggcg gacgtaaacg tcgtaaagta
    28261 gactacattg ctgctaacca tattgaatat atcgattata aagatatcga attactaaaa
    28321 agatttattt cagaacgcgg taaaatcttg ccacgtcgtg taactggtac aggcgctaaa
    28381 aaccaacgta aaattactgt tgcaatcaaa cgcgctcgta tcatgggctt gctacctttc
    28441 gttagcgaag actaataaat cctaggaatt gaatgactga tccttttgat cagctattca
    28501 attccttttt ttctgtaaaa ataacctcta ttcgtttagt cgctcgaatg acgaaagtta
    28561 tggtaaaatc aaattagtca tatatgggag gaaaattatg gaaaataaaa acaatcattt
    28621 atccccgaaa cctctcttcc ttatcctgtt tatattaatc gaagtattgg tagtcttaat
    28681 tttaccattt cgttttgtta gcgcttcggt cattctattg atgaatttat ggggtgttcg
    28741 ctattggttg aaaatgaaac gttggcttat tttaaataaa cgtgaaaaaa tccagcaggc
    28801 ttcgactgta gctgaaacca atctagctta tgtctcagaa gtcatgcctg taggagtgat
    28861 tgcttatcag ccatcaagcc aaaaaatcga atggctcaat ccattagcat tgaaaatcaa
    28921 agatcaaagt ggattaacag aggaagaatt gctagatact ttttttactg caaaagaaaa
    28981 aaagaaaaac caagtctatc tagcagataa aacatttcag tttgatatgg atacagtaaa
    29041 gggtgttgtt tattttaatg atattaccca aaaccagttg ttaaaactcc atcagacgaa
    29101 cagtcagccg gtgattggta ttttatctat tgataactat gcagatgcca ttgataaatt
    29161 ggatgacaaa gagatttctt atttgaactc tttcgtcact acactagttt ctgactggat
    29221 gaatgaatac catgtctttt tcaaaagaat caacgcagaa cggtttttct tcgtagcaca
    29281 gatgattgat ctgaaaaaga tgatggataa aaaatttgat ttgctggatc gctttcgagc
    29341 agaagctgaa aaacagagct cgcctatcac ccttagtatg gggattgctt atggctcaag
    29401 aaccctcgat gaaatcggtg gagaagctca gaataattta gatgttgctt tagtccgtgg
    29461 aggcgaccaa gttgtcgtga aagaggtaaa agaaggagca aaacctgttt attatggggg
    29521 gaaatctgct aagaatgtca aacgcacgcg tgttcgttct cgagcgatga gtaccgcttt
    29581 gcgtcggatt tttgatgaaa caggcgatgt gtttatcatg gggcacaagt ttccggatat
    29641 ggatgcttta ggctctgctt ttggtgtcag ttgtctggca cgcttcaacc agaaaaaagc
    29701 ttacatcgtt atcaacgaga acgagatcat tccagatgta gaacggtgtc ttgaagaaat
    29761 ccataagcat cctgaattag aaatgcaact aatctctcca gaacgtgcca tagagctgaa
    29821 aaaagaagag gacctcctcg tgatggtgga ttaccataaa ccttctctat cgatctctca
    29881 gggcctatat gagcaatttg ataagattgt gatcattgat caccatcgtc gtggggaaga
    29941 gtttccaagt aaacctctgc tgacttatat cgaatcttca gcttcttcag cttcagagct
    30001 agtttctgag ctgatccaat accaaagcag caaaacaaat cgcttagatc gttttgaggc
    30061 cacattattg cttgcaggga tggttgtaga tacaaatagt ttcaatgtcc gtacaactgc
    30121 acgaactttt gacgttgcca gctatttaag gtcttgtgga gcagacgcat ccttagtaca
    30181 atatttattg agctcggatt tagcgacata cttggagatc agcaatttga ttgctggaag
    30241 cgactatgtg acttctgata ttgttgtggc ggcagggaca gacgaaaaag agtataatag
    30301 tgttatagca gcaaaaacag cagatacatt gctttcgatg atcaatatca atgcagcttt
    30361 cgtcattaca aagcggacag acggcttgat tgggatcagt gccagaagta ccggcacgat
    30421 caacgtccaa atcatcatgg aatccttagg tggcggagga cacttcacaa acgcagctac
    30481 tcaactggaa aatacgacag ttgaggaaac aaaacagaag ctatttgctg caatcaaaga
    30541 aaatatgaat caaatatatg ataaggagta atccaaatga aagtaatttt tttacaagat
    30601 gtaaaaggaa aaggtaaaaa aggggacatc aaagaagttc cagcaggtta tgcacaaaat
    30661 tatctaatca aaaataactt ggcaaaagaa gcaacgaaaa gcagtatcag tcagttagca
    30721 ggacaaaaga aagcacaaga aaaacacgaa gctgaaatct tggaagaagc taaaaagtta
    30781 aaagaattct tggaaaaaga agatactgta gtcgaattga aggcgaaagc aggggaagac
    30841 agccgtttgt ttggttcgat cccttcaaaa caaattgctg aagggttaaa caaacaatac
    30901 aaaatcaaat tagataaacg aaaaatcgaa ttagaaaatc cgatccgttc actaggctac
    30961 acaaacgtac ctgttaagct tcatcatgag gtgacggcta cgatcaaagt tcatgtcgta
    31021 caagaataac aaatcttgat agcgatgttc agctggtaag tataaccaga aggaaaaaag
    31081 acaaaccgaa atttatctga gaaaacagct gcagcaatga aagcaaaagc tgcaaatcga
    31141 tttcagattg atttcggttt cttttttggg aacagcaaaa tagcataaag aaaacgagta
    31201 taataaaaga gaactatttt tttattacac tttcggtacg aatgatgact tttctctcat
    31261 tttcttgtaa aatgaagcaa ttgaagacaa ggagcgatac gtatgaatga agtgtggcag
    31321 gatcgaatcc caccgcaaaa tattgaagct gaacaagcgg ttttaggctc tgtttttctt
    31381 gacgcagaaa cgatcattga tgccatggag tacatagagc caaaagactt ttatcgtcgt
    31441 ggccatcaaa ttatttttga gacaatgatc gagttaaatg atcgtaatga agcgattgac
    31501 gtggttactg tcaaagaccg gctggaacaa gccaatttgt tagaagatgc cggtggttta
    31561 agttatctct cagacttggc attagcagtt ccgacagcag caaatatcgt ctactatgcg
    31621 aaaatcgttg aagaaaaatc attgctgcgt acattgatcc agacagcaac aggaatcgtt
    31681 acgaaaggat tcgagcaagg agaagaagtt caaacaattt tagatgatgc cgaacgcagt
    31741 atcttggagg tttcggaaaa aagaaatcga agcggctttt tatctattgc tgaagtactg
    31801 aactccacga ttgaaaatat cgatcgacta gctcaaaaca atgaagaaat cacaggtcta
    31861 ccaactggct atcaaggtct ggataaaatg acagcaggtt tccagcccga agaactaatc
    31921 attcttgctg cacgtccagc ggtaggtaaa acagcgtttg cattgaatat tgctcaaaat
    31981 gtaggaacaa aaacagatcg ttctgttgcg atatttagtt tggaaatggg ggcagaatct
    32041 cttgtaaatc ggatgctttg tgcagaaggt tcgattgagg ccagccattt acgtacaggt
    32101 cagctttcgg aagaagaatg gtcgaatctg atcgttgcga tggggagtct ttctcgagca
    32161 aatattttta tcgatgatac accagggatc aaaatctctg aaatccgtgc gaaatgtcgg
    32221 aaactagcgc aagaaaaagg caatctaggc ttgatattga tcgattattt gcagttgatt
    32281 gaaggtaacg gtaaagagaa ccgtcaacaa gaagtatcag atatctctcg ccaactgaaa
    32341 aaactggcga aagagctgaa agtacctgtc attgctcttt cacagttatc tcgtggagta
    32401 gaacagcgac aagacaaacg accagtgcta agtgatattc gtgaatccgg atcaattgaa
    32461 caagatgcgg acatcgtagc cttcttgtat cgagatgatt attatgaaag agaaggcgga
    32521 gatgacgatg atggaaacga gccaaaaaat gacaacgtca tcgaagtcat catcgagaag
    32581 aaccgaagcg gtgcacgagg aacagttgaa ctactgttta tcaaagaata caataagttt
    32641 tcgtcgcttt cgccaagaga agaattttaa agaagaggtt gtgagccttg agcaatcccg
    32701 agagctctcg taagaagatg caaggagtaa ccgcaggaac gactagagta cttaatttaa
    32761 acagatctcc aaagggattg tgacaaaagt cttgtcacag tccctttttc cgaataaacg
    32821 gtgttcaatc agctgaccct tggtattagc tcagcaaacg tcaaaatatg aggaactatt
    32881 ttgacgtttg tttctctaat actcaggtca aaacgctgat cttacgacct cttttcctta
    32941 aacggtgttc tcctgccaac tcctcggtca caagtcacaa tatcatcaaa catgagaagc
    33001 agttttttga aattgctcct tgtgactcag agttaaacgg caggctcaca acctctttct
    33061 taaacggtgt tcaaaagctt gcatctgcgg taatacgccc aatcaaacga aaaatatgag
    33121 aagctatttt tgtttggctg ttcttattac ttgatgcagg acagcttttt cacaacctct
    33181 gattcacggt gttccaaaag tagcttcttc gaaaaataag tcgaaatttc acaaaaattt
    33241 gagaagcaat tttcgtacat tccttcttat ttcttgaagc tgaccacttc tgttacaacc
    33301 tcttttttaa taaccattct aaaaagataa agttcgtttt ttaagcgttt ttataaaata
    33361 aaaataaaaa tcattcgatt ttatttgaaa tatgtatcta ttattgatac aatggttcag
    33421 gattaaataa tatagaacga ggtgttcaca tgtcatctgt agtagtagta ggtacgcaat
    33481 ggggcgatga agggaaagga aaaatcacag actttctcag tgaaaatgct gaagtgattg
    33541 cacggtacca aggtggcgac aatgcagggc acacaattaa gtttaacggt gtgacttata
    33601 aactgcattt gattccttct gggatttttt ataaagacaa gatcagtgtg atcggaaacg
    33661 gcgttgtagt caatcctaaa tcattggtta aagaattagc ttatttacat gaaaaaggtg
    33721 tagaaacaag taatttgcgt atttctgacc gcgcgcacgt aatcttgcct tatcatatca
    33781 aattggacca attacaagaa gatgctaagg gcgaaaataa gattggtaca acgattaaag
    33841 gaatcggacc tgcctatatg gataaagcag ctcgtgtagg tatccgtatt gcagacttat
    33901 tagataaaga aatttttgaa gaacgtcttc gtttgaatct agatgacaaa aaccgtcaat
    33961 ttgtaaaaat gtttgattca gaaccacttg attttgacga tatttttgaa gaatattatg
    34021 aatacggaca acaaatcaaa caatacgtca cagatacttc cgttatcttg aatgatgctt
    34081 tggatgcagg caaacgcgtg ttgtttgaag gcgcacaagg tgtaatgctg gatatcgacc
    34141 agggaactta tccttttgtt acttcttcta acccagtagc cggtggggta acaatcggaa
    34201 gcggtgtagg gccttcaaaa atcaataaag ttgtcggcgt ctgcaaagcc tatacgtcac
    34261 gtgtcggtga tggaccattt ccaactgaat tatttgatga aacaggagaa caaatccgcg
    34321 aagtaggacg agaatacggt acgacaactg gtcgtccgcg tcgtgtaggc tggtttgatt
    34381 ctgtagttat gcgccattct aaacgagttt caggtattac caacctatct ttaaactcga
    34441 tcgatgtatt aagtggattg gaaacagtaa aaatttgtac ggcttatgaa ttagatggcg
    34501 aactaatcta ccactatcca gcaagcttga aagagttgaa ccgctgcaaa ccaatctatg
    34561 aagaattgcc aggctggtca gaagacatta caggatgcaa aacacttgca gaactgccag
    34621 aaaacgcacg taactatgta cgtcgtatct cagagcttgt tggtgtacgt atctcaacat
    34681 tttctgtcgg acctgataga acacaaacaa acatcttaga aagcgtctgg gcgcaaatct
    34741 aaggataaaa acgacgactg aatcaggacg ttcttaccag agcgagtcga agtgtttatc
    34801 tatacgataa taataacttg aacactgttt attcagaata agggactgtg acaaaaaccg
    34861 tgtcacagtc cctttttccg aacaaacggt gttcaaaagc ttgcatctac ggcactaagc
    34921 ccaatcagat gaaaaatatg gagtgctatt tttatctgat tgttcttact gcttgatgca
    34981 gagcagcttt ttcacaacct ctccactaaa cggtgttctc ctgccaactc ctcggtcaca
    35041 agtcacaata ttcaacaaac atgagaagct gttttttgaa attgttcctt gtgactcgga
    35101 gctaaacggc aggctcacaa cctcttggta aacggtgttc aatcagctga ccctcggtat
    35161 tagctcaaaa aacggcaaaa tatgaggaac tattttttcc gtttttttct ctaatactca
    35221 ggtcaaaacg ctgatttcac aacctctgat tcacggtgtt ccagaagtag cttctacgga
    35281 aataagccga aatttcacaa aaatttgaga agcaattttc gtaaattcct tcttatttct
    35341 tgaagctgac cacttctgtc acaacctctt attttgatta gaacttgcga aaataaaccg
    35401 gttaaagtgt gtctagcgca agagatttgc tataatagac gataagggta aaatgtaacg
    35461 agaaggggtt gaaaaatgtg tatcaaattg taacagattc ttgttgtgat ctgccatacc
    35521 atgtattagc aaaagaaaaa gttgattttt tatcaatgaa tctccaattg aatgatcaag
    35581 agttagtaga tgacctcgga aagacattca attatgaccg ctacatgaat cagctgaaaa
    35641 atggtgcgat gcctacgaca tcacaaatca atgttggccg atatttagaa tttttccgtt
    35701 cttatgcgga aaaacagatt cctgttttat atgtggcttt ttccagtgga ttaagcggct
    35761 cttacagtag tgcgcttcaa gcggttgaat tgctgaagga agaatatgaa gaccctgaga
    35821 tctatgtttt tgatacaaaa gctgcaagta ttggggaagg gcttttagta ttggaagctg
    35881 taagattgaa aaaagaaggt aaaagcatcg aagaaaccct agagtggctg gaaagtaatt
    35941 atttgaaagt ccattcatgg gtaacagtag acgatctgaa atatctagaa cgaggcggta
    36001 ggatttccaa agcaagtgct actcttggca gtctattgag tgtaaagcct attattacgg
    36061 tggataaaga aggaaggctg acgaatgttg acaaagttcg aggaagaaac aagtcgatcc
    36121 agacaatcgt caatgagacg gtaaaaacaa tcgttgcacc acttgatcaa atcgtttatg
    36181 tggcttacgc tggggatcta gagagcgcgg agaaggcaaa acggcttttg gaagagcaga
    36241 taaagatgaa agatgtgaag ctttatccct taggaccaac gatcgccagt cacacaggct
    36301 atggctgtat cgcgattttt tcgatgggaa tcagtcgata aaagcagtaa ctcattctgt
    36361 aaaaaagccc agaaattgat tgtaacaaaa acagcgactc ttaaaagata gatgagcatc
    36421 ctatctctta gaggtcgctg tttttttatt ttttaagcta aataggccat tatgcccata
    36481 actcgttcaa ttgtttttga atatctgcat tttccaaaaa ttcatcatat gtcgtatcag
    36541 ctcgatcgat cacaccttta tccgaaacgg caatgatgcg gtttgccaat gtttggataa
    36601 attgatggtc atgtgacgca aataagattg agccagtaaa tgccatcaag ccgtcattca
    36661 atgctgtgat tgattctaag tctaaatggt tcgttggatc atctaataca agtacgttag
    36721 ctttcgaaag catcattttt gaaagcatgc aacggacttt ctctccacca gataaaacat
    36781 tcactggttt caatacttct tcaccagaaa acaacattct tcctaagaag cttcttaaga
    36841 aggtgttatc atcttcttct ttacttgcat attgacgcaa ccagtctaaa atcgttagat
    36901 cagtatcgaa ttctttcgtt gtatcctttg gtaaataaga attacttgtt gtcacacccc
    36961 aacgtactgt tccagtatct ggcgtaattt cacccatgat aactttgaat agcgttgttg
    37021 ttgttatatc attttctgcg acgaaagcga ccttgtcttc tttgctcaaa ttaaaagata
    37081 tatcatctaa aattttcttt ccatcaatcg ttacacttac attttctacc tgcaataagt
    37141 cgtttccaat ctcacgttca ggtttgaatc caacgaatgg ataacgtcta gaagaaggtt
    37201 ggatatcgtc taaagtaatt ttttcaagca tttttttacg tgaagttgct tgttttgatt
    37261 ttgatgcatt cgcactaaag cgggcaataa attcttggag ttctttgatt tgttcttctt
    37321 ttttggcatt tgcgtttgct tgaagtttag ccgctagttg actagattcc aaccaaaaat
    37381 cataatttcc tacataaagt ttgattttac caaaatctag atccgccata tgtgtacata
    37441 ctttgttcaa aaagtgacgg tcatgggata caacgatcac agtattttca aaattgatca
    37501 aaaattcttc cagccaattg atcgattgga tatccagacc gtttgttggt tcgtctagca
    37561 aaagaacatc aggtttacca aatagtgttt gtgctaataa cacttttacc ttttgtccac
    37621 cagttaattc actcatttgc tgatggtgca attcttcagg gatgttcaga ccttgcagta
    37681 aaacagctgc ttctggttca gcttcccatc cattaagctc agcaaattct ccttctaatt
    37741 cagctgctcg aataccatct tcgtcagtga aatcctcttt catgtaaatc gcatcttttt
    37801 ctttcagcac ttcatacaga cgcttgtgtc ccatgatgac tgtttcaagt acagtatagt
    37861 cttcatagtc gtaatggttc tgtttcaata cggccatccg ttcatctggt cccatagtaa
    37921 cggaacctgt ggaaggctgc agatcccctg ataacacttt aaggaacgtt gatttacctg
    37981 caccatttgc accaatcaag ccatagcagt ttccgggggt aaatttaata ttcacatcat
    38041 caaatagttt gcggtctgaa aagtgcaaac tcacatcatt tacagtaatc aatttttttc
    38101 ctcactttta tcattattag ttttgacaag tcttatagaa ttatataggg gaaaggtaaa
    38161 agattcaagg caatcgaaca ttctttgtgt ttcacgtgaa acagaatgaa aaaaataaaa
    38221 ataaaagcgg agcgaaaata gctactatag gatttattag tttgcaacag cataattttt
    38281 gacgttattt ataagaggga gtactataaa actgtaaaag aaatgaaaga aggattgaaa
    38341 atggatgaaa aaagaaccat cgactggggc tcattgattt tgggaatttt atttgtactt
    38401 gtctcattgt tatcatttca agaccctgtc ggaaatttag ttgcaattgt agtagtcttt
    38461 gcgatttttg cctttattaa agggatattt gaactgtttg tacggaacag attaaaagag
    38521 ctaacaggat ataaaggaaa gatgccctta ataatcggga tcatcgatat tctagttggc
    38581 gtctttttct tattcaatat tggtgcagga gtcgcagcat tgccttttgt ttttgcagta
    38641 tggtttattg ctgattcagt tttagcgtta tttactgctg acttggcaag aggagtaagt
    38701 gaaggatatt attggtttac gatcatcgtc aatattttag gaattttatt aggaattttc
    38761 ttattgttta atccaatttc ttctgcgttg acattaagct ttttagttgg attctatttt
    38821 atgttatttg gtatcacaca tatcgtctat gcatttagat aagtaaaatc aaacaaataa
    38881 aaaagccggc ttccgattac agttttactg ttgtaattgg aagccggctt ttttatcatg
    38941 gacaaatatg cacgaggtga tttttaggtg tcgagacaaa tttatgcaaa aatgtgagaa
    39001 gctatataca caaattttat cttaatactc gaagcatagc gcagttgtca caacctcttt
    39061 tcatataatt cattcaatac tggcaaatca tggacttcat atttttcttt gaatgcttgg
    39121 atttcttctt cagaatattt tcttggatct aaatgcagat cttctactgg caatgggcgc
    39181 ttgttattga tcttcacatc gattactaca ggacgatctg attttgcagc tgcatcaaag
    39241 gcaaatcgaa gttgcgagta ttctgtgact gtaaagctat ttgccccgag cgcttctcca
    39301 actttaccga aatctgcatc ttctaaaaat acaccaaatt tcttttgttc cgtatcttct
    39361 tgttctgctt cgatgaaacc aaaagaatca ttcgaaaaga caacattaat aattggaagc
    39421 tgatatttga cttgtgtaat gatatcttgc atgaccatag caaacccgcc atcaccactt
    39481 aaggtaaata cttgtttttc tgggtagctt agttgtgcgg caattcctcc tggcacacca
    39541 ttacccatag ttgcgaacca tccagatgtc gtatgttttt gtttaccgtt catattcaat
    39601 aaacgaatag aatggatagt cgtgttaccg acatctgtga cgaaaatcgc atcgtcttca
    39661 gcaatacgat tgatttcttt atagacagcc tctggacgaa tcggttcttc ctctcgatct
    39721 tcaaaagatt tcaaccaatt tacccatttt tctttatttt cttgatttgc taggtaccag
    39781 ctatcagcag ggcgagcatc ccctaactcg acaagtcttt gcaaagctgt gtttgcatca
    39841 ccgaggatcg acaaagatgt ttcatggcgt cgtccaaatt ttgacgcatc gatatcgatt
    39901 tggataaatt cagcagttgg attaaaaaat gcacgtccaa atgggaagtc gctaccgaca
    39961 aataagatca gatcggcttc tgccaatgct tcatttccgg gtttagtagc gacacgtcca
    40021 gcaaaaccaa gaaagttttc ataatcatca ggaataattc cttttgctag aacggaagcg
    40081 acaacaggaa ctgaaaaatg ttctgagaat tctttgattt gcggaaatcc gtttcgcgtt
    40141 ccttgaccaa cataaagaac tggttttttt gctttttcaa gataaggcaa agcagctagc
    40201 aaatcttttt cttctggtaa tatcacactt gttttgtgag tgtgagcggt ggagaaaggt
    40261 tgttcgtcaa tttcttcaaa accaagatca acagggatag tcacgatagc cacgccttta
    40321 tgctcatagg cggctttaat ggcttcatct actacatgcg gaagactttg tggtgtcatg
    40381 actgtacgat tgtatacgct aacatctgcg aaaataggat tttcatttag ttcctggaaa
    40441 gagttatagt tcatggatgt agaagcaact tgtcctaaga acgctactag aggcacatgg
    40501 tccatctgtg catcatacaa accattgatc aaatgtgtcg caccaggtcc tgcagagccg
    40561 aagacagcgc cgactttccc cgttaatttt gcatctgcag cggctgcgag tgcgccgact
    40621 tcttcatgac gaacttgaat gtagttgatt tcggtttttt cttgatatag cgcatccata
    40681 attgaattga aagatcctcc gggaatgccg taaatatggt cgatacccca gctttcaaga
    40741 acttttacca ttgcgattcc tgcattgatt tttgacatgg tgtttcactc ctttagcaat
    40801 gatgatacat aaattttttg tatctagagt atagaacttt ttatcgaaaa tcccaactaa
    40861 ttcgtctttt cacaaaaatg tagtcatgtt tttgggaata tgctagagta gtacatagat
    40921 agattcaaga gaggggaatg gcatggttga atggctattg agacttgaac cttggcagca
    40981 agcacttgct gggacagctt ttacttattt tatgacagct cttggtgccg ggttggtttt
    41041 tttctttaaa gaaatcaaaa aagaagtgct aaacttgatg ttaggatttg cttctggtgt
    41101 catgattgct gcaagttttt ggtctttgtt agatccggct attacaaaag cagaagaaaa
    41161 tggagatatt gcttggctag ttgtaagtat tgggtttggt ttaggcggtg tgtttttata
    41221 tatggcagat aaaacactgc cccatatgca ttttggacca caacatgaag cagaaggatt
    41281 gcctacccat ttaaaacgga cgatcttgct tgttttttct attacattgc ataacattcc
    41341 tgaaggttta gccgtggggg tagcattcgg tgcagcagca actgcggata atccgacagc
    41401 cgctatatta gccgctgttt cggtggcgct aggtattggt atccaaaact tcccagaagg
    41461 agcagctgta tcaatcccgt tgcgacaaga aggtctgagt cgtaaaaagg cctttgttta
    41521 cggacaagct tctggaatcg ttgaaccaat tgctggagtg attggagcgc tactagtaac
    41581 gaaagtggag ctgctgcttc cttatgcact tgcttttgcc gcaggagcaa tgatttatgt
    41641 cgtggtggaa gaattgatcc ctgaagcaca gcagacattg tccagcaaac gtcattttgc
    41701 agtttttggc gtcatgagtg gatttatcat tatgatgatt ttggatgtgg cattaggata
    41761 aataaaaaaa atatatatga tatatcaaat agggccgcga acttatatcg cgaccctatt
    41821 tttttagtaa gttatatcat aatgaagtga atggtatcat acattaataa tagttttttc
    41881 tatgtgtatt tcctttgatc cagcgaacaa gccagatgat aagtgcgatt gggattagaa
    41941 ctttgaccgc aaaccataaa agcccgctta ggacactgac aaaaagactg atgacgaagc
    42001 tagctgcaat tagcactaaa agaaccatga agatatttaa gaacatattt ttttgacgca
    42061 tacaaaaccc tcctcttgtt cattctttac tatagaaaaa gtataacagg gattgtttaa
    42121 aaacacctcc aactgaagac tgatttttac ttcatctact taaatgatca aacaattgct
    42181 ttttctctgg tttatcatct aaaatagagc ggaaaaggag gagaatatca tgcctaaaaa
    42241 tcgtcttgaa gcatttacag atgctgtaat cgcgattatc atgactattt tagttttaga
    42301 acttcatgaa cctaacggag acacgtggga ggcgctcgct gcattaggtt accgattttt
    42361 tatctatatt gtcagtttta tcattttagc gatttattgg aacaatcatc atcatttatt
    42421 tcaagttgta cataagataa atggacgggt cttatgggcg aacagtttct ttgtttttgc
    42481 gctttcgctt tttccgtttg caacttcatg gatcagtgag tacatcaata gcctggctcc
    42541 agaaatgact tatggttttg ttaccttgac cgctaatatt gcgtattata tcttggcaaa
    42601 agaacttgtc aaagcaaata aaggccacga gaaagcattg aaggcgatgt tgaataatta
    42661 caagaaatcg tatctatcga ttggtttgaa tgtgttagga attgtcttag ggtatttagt
    42721 agcgccagta gccgtgctga tcgcaaacat cgtgattcta gctgcttgga tcatcccaag
    42781 tcgtaccatc gaatcacaat atcggtaaaa tgatccgtgt ttaaaattta agagaaaaat
    42841 atagaaaaaa taaataaacg atcaaatatc cgagtgatac tagtattcaa agagggatgc
    42901 agatggatca aaaaagaatt catgtaggac tgattactag ttttgtcacg atgcttattt
    42961 atttggatca aggtcatttg acttggacag tagttggtgt cgtaggattt ttgacattat
    43021 tcacagcaat aaaaaaataa acatctttat gtaatctgat gttctatcta tttaagaaaa
    43081 gcatgtttac agcagtatga ttctgttgta aacgtgtttt tatttgtgga aaatttaatt
    43141 tttagaaaag tgtatcgaaa aatagatagt tagtttttcc acagtggata acttcgtaag
    43201 agataaaaat aaaaaattag tcaaagaagg gcgtatagat ttcttttgat aggagatata
    43261 caacagaaat gaataaatat taacgtgttt tcaaacagta taaaacggtg tggtttttgg
    43321 aataaaaaaa taacatatct cattttacgc ttttgttatt ttatacttaa aaaataacga
    43381 cacagaaaat accgtgtctc agatttctct actacttcta aaaactactg tttttttcct
    43441 ttgaaatgcc ttcaaaaagt aggatcaggc agaatatact ggcagaatca aggagaaggg
    43501 agcctaaata aggagaaaaa ccatagaaaa tataaagtaa ttacttataa aacaagcttt
    43561 ttatagaaaa ataatatacc tgagtagggt ataaattaag acggaattcc tttctagatt
    43621 gagatattga ctaggaagaa tgttaagatt ttaagccttt aagctaaaaa aaaacccttt
    43681 ttgttaaata aggggaatat agcctgtcag tttcaaactg caagtcgtcc tgctgcaata
    43741 atatagtaga ttagagatga aaatagattt ttttaaacca atgactgaat aaaaagaccg
    43801 tcatagatac acattggaat gtgtctatta cggtcttttt ttacgaacga ttttattgaa
    43861 gacggacagt tcgggtcaaa aataaaaaag ctacgatcag aaataagaat aaaatgtatc
    43921 ccaaaataat ggctagacgg tctaacttat ttgtcgatag atgtttgttt agaagttgat
    43981 aggcccataa acctatcagt cctcctgttg tattagttat caaatcagtg atgtccgcta
    44041 cgccaatacc gaataggaat tgaatcaatt ctgccaagaa gcttacaagg aaaataatcc
    44101 ctaatttttt agaaaaagaa agtctcttga aattgacatt caaaagcacc ccaaaaggaa
    44161 aaaagacaat caagttataa gtggtctcac gtaataccgt cgtattttca aaagaaaaag
    44221 tagaaaaagg gacgagattg acattgctgt aagaataagt gagaaattgt ggaagattaa
    44281 atgatagctt gaataaaatc aaccataata gaaagaataa ataaatccct aataaaaatt
    44341 ttgatacata ccgcatagac atctcctcca tttaaaaagt ataccatcga aaaccgctga
    44401 aaaatcataa aaaagtatga agtttaagga ccaacgtagt tatcgtacga aaattagaag
    44461 cttttttttg ttgggaatcc ggtttcttta acaaagctaa gatagcgagt tgcttggaaa
    44521 agttgctatc ttttttctgt caaaacgact cggaatgttc gttttttgtt ctaatttctc
    44581 caagttgttt actttttgat actaagttta tgaaaaatca agaaatagtt gttatactag
    44641 gtaatgctga caaacgggat tggcatttca tcttggttca gctttttttc caattactag
    44701 gaaggaggga tagattgttc aagacttatt ttcgtttcaa taaaatacaa gataatcctt
    44761 ttcgtatcat gaatctgatg ctacttatct ttattgtatt atggttaggt tacataaatc
    44821 atgatttttt gatttcaagt ttttcatcat tagggatctt tacttttttc tattatcaaa
    44881 acataccgat gaaatatttg ctgaaacgta tgtttctgat cggttgcgga ctgttggttg
    44941 ctttcgtttt ggggatctta tcgacttatg ttttatggct tgaaccattt gccgtagctt
    45001 tggttgcttt ttccagcaga ttcgtgttgc gattattcca tatttctaaa ccaggtggct
    45061 tgttttttgc gatgctttct gccatgggaa cgagcatgca gctgccaatc gctcaattac
    45121 cgatcgtctc actttatttt tttatgggtg tcgtttttgc cctgattgcg gcagtgatta
    45181 caaaattact ggattcacgg cctgagcaga caattgaaaa agcaacttta aaagaaagat
    45241 ttcacgaaga gcctttagtg atcattgatt ctgttttcta cagcgctgcc ttatttcttt
    45301 ccgtttatgt cagtcacggc ttgaatctgc ataatcctta ttggttgacc ttgtcatgtg
    45361 catcgatttt gctagcagaa aacttggatg cgatgaagca tcgacaagtc caatatctga
    45421 ttggatcgat gggtgggtta tgtgtgtcgg cattcttgtc atttgtgccg tttacgcagt
    45481 tgcagaccat ttttctgatc acttttctat atggaatcgc acaatttcta gttgctagaa
    45541 attatgcagt tgctaatatt tttcttaatc cgatggcgtt gatgctatct acacttattc
    45601 gtggagcata cttgatttct ttgatcgaat atcgtttttt agggatcgtc ataggaagtt
    45661 tcatcggttt aggtgttgcg tgggtaatga cggttggttt gcaacattat ttaacggttg
    45721 ttcgtcaaaa attagaatag aaggacaaat atatgtgcca aaagaggtta tgacaagatt
    45781 tttgtcacaa cctctaattc aaggtgttca aaagccagat tctcagcatt aagtcaaatt
    45841 cacacaaaaa tgtggaaagg aactttcaaa aaaattttat atttattcta tcaaaaaatt
    45901 ttgtttatga tggtaactga ataaactttc ctgagatggt caatgctttc cttgaaagtc
    45961 ttacagatat tctttcttca tagaaagttt aagttttata gttagtgtac aataaaagta
    46021 tgtttatacc atatggtgtc cggataatca gtcatttaaa caatgaggtt caaagatatg
    46081 aaaaggggaa atttgatgaa gaaaataagc aatgaaatcc aaattctggc agaaacttta
    46141 actcttccca aagtcgttat agagcaaatg attgtacaag caaaaaacat ccttgatgag
    46201 gtgtttgagc aatatagtca tgaactaatg gatcctaata aagcaaaggc gactgcaaag
    46261 aaaatagaca aagtctatga agaggaacct tttgcagcat tagctattta tctatatgca
    46321 gcttctcaaa gttggaaaaa aatttatcaa ccattgaaga ttccaagaac tatctatttg
    46381 gcaacaatga atgcttttac tagatttatt catgaacatt tccaagtaac aggaagctat
    46441 cgctttgacc gtggtttttg gatttggcat tacactagtg gcttgatctt tcggattggt
    46501 gaattggagt acgaaatgac atattttccg aaagggtaca cggatctaag attagaagga
    46561 aagcagtgcc tttctcttca tattccttcc gatgcagatt tatctcagaa taagataaga
    46621 gatagttacg aaagtgccat tcgttttttt gaactttatt ttcctgatta ccattaccaa
    46681 gtgatgtaca cagatacttg gttactatca cccaatctta ctaaatggtt gaaaaaagag
    46741 tcaaaaatct gtctttttgc agccgattat cgattattat cagttgatga acaggacgat
    46801 agtggagtcc cttggatctt tggacgagta gatgcccaaa tacatgatta tccagaaagt
    46861 acgagtttac agcgacaagc aaaagagcaa ttgcttgcag gcgagcacat tggctctggc
    46921 ttaggtattc ttacttcata agtttagtac ttcgaaatag tttaaaagag cgtgagacaa
    46981 aagtaaagaa cacttttgtc tcacgctcta aacacgtata aacggcggaa gcagaagcaa
    47041 ctccttcgga aataagctga aattcacaaa aatttgaaaa gcaattttcg tgaatttctt
    47101 cttatttctt ggagttaaac gcttctgtcc cagcctcttt tttagtgttc tatcgaacac
    47161 acagtacgtt caataggtaa actagctata acaatagata ttaaagttaa cggacaagag
    47221 ggcctttttt aggtagctaa aacgtaataa tgaaaattta tttccagaga taggagtcaa
    47281 tcagctagtc tgatcgactg ttttaacaag ttgactttca ttttaacttt tgataccatt
    47341 taaaacacaa atcgtaattg tttcgatttg tgttttttag catgactaca atcaaagaag
    47401 aaagtgggtc gtccatatgg aaaaaacaga tatctcaagt gcataccgcc gcttgaaaag
    47461 cccaaatatc aaaacacgaa aacgtgcgct gaagatcatc aaagatgtga aacggaatag
    47521 tgggaaaagg taagaagaag gaaacttaat taaaaaaata gccgaaaaac gtttttcggc
    47581 tattttcaat aatcggtttt tgtgtaaggt ttccgaaaga actgctgttg attttccatt
    47641 tttaacatat gataaattgg tagaatcttt cttttcaaat tgataccatt ccctaattcc
    47701 agttatatag ttaactacag aaccacaaag cacgtacgtt tataaaagta ttatctgtag
    47761 ttatttttca attccctttc aacctcttat tttgaccagt agtattgatc actttacctt
    47821 ttaacacctt tgttcgtttt tgaaacattt ttagtcaaga atggaaacgt aactacataa
    47881 tcaaaggttt tgcgaaatat ttcatgaaat atttcatgta gaagcgagca atacggttgc
    47941 aaataaccat tatcgtttaa taagcagtta cgaaagctcc caatatctct aacgttcagc
    48001 tcactccatt tcttttcttc aaaaaaatca gtgattcgta tctctttcta tttgtcgaaa
    48061 aagttaactt taaaaagtaa cgccgaaaaa atatgcaaaa aaataaaaaa gcagttacta
    48121 ttgctagaat aacatcaagg aataataagt tttggttttc agataatagt cgataagttg
    48181 tgtattggaa ttttagatac agtaataaag tatttttcat gaaattttgt gagaatcact
    48241 attacaagta tctttaataa aattaatggt taaggaggaa cttaaagtag aatgtaaatg
    48301 aatagttgta gtcagtcgat tgtgatacta gactcaaagt tgcaggaata agtttttcaa
    48361 tttgtgattg gaagataaaa aatgaaaaag aagggctttt ttttatactt tgttgattgt
    48421 agtgtttatt ttccctctgt ttagccaagt aacattttct atgactcaac cagtttcaag
    48481 tgaggaacat gataaccttt ttcgtgctac agaagagttt aagaaatatc aggaaaatat
    48541 tgttccggag actccattag ctagtgagcc aattactgat attgatggaa accaaatagg
    48601 atggtatata cagtacgaag ttatggtggt aaataatgac tcaatagtaa aaaatacagt
    48661 aggcttagag ctaacaccga ttgaaaaggt gagttcattg ttaacgtata tttatactga
    48721 tgaaagtgac gagactgaga tcattttaac ggattactca aaaattgcta ctgataaaaa
    48781 gtatatattg tggatgtaga cactagtgaa atactttatg atatagaaat tgatgaaaat
    48841 ttactagatg tagcacaaga aatcgatcat caaaagcagg aagctattcg atatgctggt
    48901 agaaaaggga aaagaaaata tttattacgt gaatgtagca aaagttagag aagatgaaaa
    48961 tgagtggaaa gaattcaaga gtcgctactc aattaactcg actccgacat ttacagttta
    49021 cagagaagga tcgatagaaa aaactgtttt ttggactaaa gaaagtggaa tgtctttagc
    49081 tgaagtagaa gagtttttgg attatgttag tatgcaacag taagggagtt cttattatga
    49141 aaaattttga cacatattat gttattgttt tttcgatatc tttgctgtta atattactaa
    49201 ctttaatgca gtataaagag tatccagagt attttatttt aacttttgta tatttagtaa
    49261 gtagctacac acttctatat aaattcagaa gttcttctag agtttctaaa gtttgtttct
    49321 taattagctt attgattcta taatattttt gatttatata ggaaattaaa aatattatag
    49381 aatcaacact cagagaacgg gttggttttt aatagattta ataagtactg ataatgaaat
    49441 ttctcctggt tgggaaaacg aagttggtta ccctgtagaa gaattttttc aagattactt
    49501 tgcggagtat gccgatagga taatgagaga ttacgtaaca gataaaactc aagaagtcat
    49561 caatcaatcc cagtcattaa atgaattatc tgataaggcg aaagaagaag cagttgccat
    49621 tatttcttca gggattagtg actatattga tatgagtggt gaaatcaatt atggcgataa
    49681 agacaaaatt gtacgcatga taaaagcttt tatcaaaact tttgatgtga aggcagatct
    49741 taagtttaat gatacttacc tagtaggaaa attaattaat atccttggga cagagaaaga
    49801 tacggaaacg tttatttcct ctttgtctat gttgtttaca gataagcatt tttcaactca
    49861 gcttggtgga gaggaactag tggaaatctt ttaaccatta cgcccagcat taataaaagt
    49921 atatcaaaaa agtactcctg atgattttta agattggttt gagaaataat gtgaaaacac
    49981 tatttttaat gttaattata gatagagatg aacgcgtcat atggttaaaa gaatgaaaaa
    50041 gtcaaagata cactgctata tttcactaag gatatagcag tgtatctttc atgtcgtttc
    50101 actggcagtt ttttataaaa ggaggtgtgc atttcagttg cttttctttg gtagttagtt
    50161 gaatcgttta agaattaacg gatgtggcag acaggtgctc tgtccaaaaa ccagtaaaat
    50221 ctttgatggt tccatcttta tttagctgtg cctgttcaaa tactgttttg tttttaccga
    50281 atggatcaat tgcaataatt gttccgatcc ccgcacgttt ggcagcaagt aatcctgagt
    50341 aagcatcttc gataacaaga caatcagccg gagctaagct cagtttgtct gccgctttaa
    50401 gaaaaatatc cggttgcggt ttcccaggga aagagccgtc gtcatagaca atcttgtccc
    50461 agtcaaacca gcgggctaaa tcgaaaatat caaaataaaa agcaacattc tctttgacag
    50521 tagccgtggc aatcgttaat ggaatctgtt ggtcagtcag ctggtcaaga gtcgcttcaa
    50581 gcccttttgt caactgaagc tcgttttcat tttgcaagca aagcatacga taatagcttt
    50641 ctttttcttc tgacaatacg gcgatctcag aggcggtcaa atgctctgaa atgaaatgtt
    50701 tcaaaatctc cgtattcgtc cgaccatgaa tattttttaa aatatcctcg tctgataaac
    50761 catcttttgt atgatcatgt atcatatgca gccaagcagc ttcatgcaga tgagagtcca
    50821 aaaacattgt tccgttgaaa tcaaatataa tccctttcat agttacgctc ctatagtggt
    50881 attttcggtt gaatcagcaa tttgcagatc gacatattgt gcatagtgct cttgaacctc
    50941 ccgcgagatc tggcgatccg taatgagcag atcgaaatca tgcaaattat aaaacacata
    51001 aaaatcatct cgattgaatt ttttattatc aacgagtaga tatttcttac gggaattatt
    51061 tagagcgatc tgctgtgctt ctccttcttc ggtactgtaa gtagagatcg cttcgttgtg
    51121 aacgccattt gaactgataa atgcttttgt aaactttagt cttcttaaat tgtcgttggt
    51181 gatcggtccg acaaatgcgc cggtattttt ccggaaatca ccgccaatca gtagaatttc
    51241 tggtccatct gcttgagcaa gaatatcaaa aactggataa ttatttgtaa tgatccgaat
    51301 tttcttgttc agtaaatgcg tcgccaatag ttcgattgtt gtacctggtc ctaagaaaat
    51361 cgtttctccc tcgtgaatca aggaggctgc tgtggcagca atttcttttt tttcttgaat
    51421 ctgcagagtg gctttttcag tgtgagaaag ttcttgatct aaagtgtagg aaagactttg
    51481 agcccctcca tggacacgca gcagcttgcc cgatttttct aattcatcta aatctctgcg
    51541 aacggtcata tcagaaacat ctaattgatt gatgatttca ttaacggtaa ggattccttt
    51601 tttattgacc atttctacga tagtaagcaa tctttctttt ttcaacattg tcttcacctc
    51661 taatttaagg ataatctatc atataaacgg acaacagtca atctaattcg aacaaaagta
    51721 aacatttagg gtggttttta tgtttgttac aatagatttt attgctgttt tctggttttt
    51781 atgattattt gtgtttgttt ttgttgacaa atgttttgga tgcgtttaca atgcaatcag
    51841 ttagaaagag cgaaaactga ttatagattt gaggagagat gtacatgctt aaattaccag
    51901 aagattttat ttttggcgga gccacagcag cctatcaggt tgaaggagcc actaaggaag
    51961 gtggcaaagg cgctgttgct tgggatgact ttttagagga acaagggcga ttcagtcccg
    52021 atccggcaag tgatttttat catcaatatg caaaggacat tgaattgtgt gaacgttttg
    52081 gtgtaaatgg tctaagatta tccattgctt ggagccgcat ttttcctgat ggagctggga
    52141 aaccaaatcc agaaggaatc gctttttatc atcgtgtgtt cgaagaatgt aagaaaagaa
    52201 acgtaacgcc gtttgtgacg ttgcatcatt ttgatacccc taaacgtttg tttgaccatg
    52261 gagatttttt gaatcgagaa acaatagaag catttgtttc ctatgccatt ttttgttttc
    52321 atgaattcaa agaagtcaag gtgtggagta cctttaatga aatctatcca gttgcaacca
    52381 atcaatattt gttaggtgtt ttcccaccag gaatcaaata tgattttaca aagatcgtcg
    52441 cctgtcttca taatatgatg gttgctcatg cccgtgtagt gaactatttc aaagaaaacg
    52501 aacttccggg tgaaattggt gtagttcact cattagagac gaaatatgcg gcaacagacg
    52561 cgccggaaga taagcatgct gcctttttag acgatgcatt gtcgatccgt ttcttattag
    52621 atgctaccta tttaggctat tattcaactg aaaccttgac tgctcttgat gagatatgtg
    52681 aagcaaatca ggccagctat cattttcctg aagaagattt cgttgaattg aaaaaagcat
    52741 ccacgcgtaa tgactactta gggatcaatc actaccaatg ccattttgtc aaagcttacg
    52801 atggagaaaa tgcaatccat cataacggta cgggtgaaaa agggacctct gtttataaag
    52861 tgaagggaat cggagaacgt atttataaag aaggaattcc tcgaactgat tgggactggc
    52921 tgatttatcc agaaggtcta tatgacttgt tgctgcgaat taaaagcgat tacccacatt
    52981 acaacaaaat ctatatcact gagaacggga tggggtataa agatcagttt gaagatggca
    53041 ttattatgga tcagccgaga atcgactatt tgagagtcta tttggaatcc ttaagcaagg
    53101 cgataacagc cggggtaaat gtgaaggggt attttttgtg gtcgcttatg gatcttttct
    53161 catggacaaa tgggtataac aaaaggtatg gcttgtttta tgttgatttt gaaacccaga
    53221 agcgttaccc aaaagaatca gcttactggt acaagttggt cagtgaaacc aaaacgatta
    53281 tttaataagt gataatggag gaagaaaaga tgaataaaga ggaattacaa atgcttggtt
    53341 ttgagatcgt tgcatattca ggcgacgctc gcagtacatt attgaaatta ttgaaagaag
    53401 taagacaagg aaactttgaa catgttgatt cggcgttgaa agaagccgac gaaaatttaa
    53461 cccttgcaca taattcgcaa acaaaaattt tagcggaaga agcatctggg aaagagatgg
    53521 agatgggatt catttttatc catgggcagg atcatttaat gaccacttta ttgctgagag
    53581 atctgattca agactttatt gtactgtaca gacagaatca aggataggag aagaacgcta
    53641 tggatggaat cattaaacaa atcgaaaaag ggaaaccatt ttttgaaaaa atctcacgta
    53701 atagttattt aggagccgtt cgtgacggat ttttaacagc gatgccagct attttatttt
    53761 caagcatttt cattttgatt gctgcggttc ctgagatttt tggttaccaa tggcctgaat
    53821 ctgtctccac atggctatgg aaagtctata attattcgat gggtgttgta gggttactcg
    53881 tttcagcaac cactgctcgc tgcttggctg attcgatgaa tcgtcgctta ccgaaaaaca
    53941 aagtaatcaa caccacctct gtgatgctgg cctctgtggt aagtttcctg ttgttaagcg
    54001 tctctccgat tgaaggtgga ttttcaacgg aatatatggg gacaaaggga ctactggctt
    54061 cctttgtcgc tgcattttta acagttaatt tatataagtt ttgtgtgctg aaagatatta
    54121 ccattaaaat gcctaaagaa gttcctggaa cgatttcgca aaccttccga gatatttttc
    54181 ctttctcttt ttcagtattt gcggccgttt taattgattt aggcattcga caaatcttcc
    54241 aaatctcatt tgcagaagca atcattacgg tgctgcagcc gctatttaca gcagctgacg
    54301 ggtacttagg aatcgctatt atctggggag cgatggcgct gttttggttt gtcggtgttc
    54361 atggaccgtc gatcgtggag ccggcaattg cggcaattat ctatgccaat gtggaaacca
    54421 atctgcaatt gttcaattcc ggtgaacaag cttctaaagt actgacggtg ggtttaggga
    54481 attttgtagg aactatggga ggaactgggg caacattggt tgttcctttt atcttcctac
    54541 tctttgctaa gtctaagcag ttgaaggcag ttgggaaagc ttcctttatt ccagtaagtt
    54601 tcgctgtcaa cgaaccattg ctatttgcgg cacccatgat tttgaaccct tattttttta
    54661 ttccattttt gttaacacct gttgtaaacg tttgcctgtt caagtttttt gtcgatgtat
    54721 tgggcatgaa cagctttatg tacgttttgc cttgggcaac tccagcaccg atcggtttgg
    54781 ttctaggaac gggcatgggt atcttagctt ttgttctagc agcggttcta atcgtcgttg
    54841 acttcctgat ctatctacca ttttgcaaag catacgatgc tgtcttagta gagaaagaag
    54901 cacaaaaagc agaggtgatc gcaaccgagg aaggtgcttc tgccgatgta cgtgaggaag
    54961 tacctgtggc agcgagtcaa gttatcagcg atgcaaataa agaaatcaat gtgttggtac
    55021 tttgtgctgg cgcagggaca agtgcgatgt tagctaatgc tttaaaaaaa ggtgcatctg
    55081 aatcgaaagc accgatcagt gcaatggcgg gtgcttatgg ttctcattac gaaatgctgc
    55141 aggattttga tatggtggtc ttagcaccgc aagtcaattc ttactatgat gatatcaaag
    55201 aagacaccga tcgcttagga atcaagctgg ttgcgacaaa aggagcagaa tatatcggat
    55261 taacgagaga tcctgaaaaa gctgttcagt ttattctgaa ccaatttcaa taaaggagga
    55321 gccataatga aaatgggaat ttggttgcgt aaagctgttt tatttgcagc tgtgttaggg
    55381 gctttggggg ctgtttcaaa aactgttgaa gcatctgcca gcgaatttat tcgcggagca
    55441 gatatttcga tcctgtcaga tatggaaaaa tctggtgcaa aatattatga agacgatatt
    55501 tcaaaagatg ccttagagat tttaaaaaat aatggtgtca actatgttcg actgcgtttg
    55561 tggcaggatc cttataatag taatggagaa agttatggag cagggacaaa tgatctggaa
    55621 acgacgattg accttgcaaa acgagcaaaa aatctgggac ttaaggtgct gctggatttt
    55681 cactacagtg atttttgggt tgatcctggg aaacagaatc ttcctaaagc atggcaaggt
    55741 ctgacctttg aagaaatgaa tacggcattg tacgactata caaagaacgt tctgtcggaa
    55801 atgaagcagc tggacgttta tcctgatatg gttcagatcg gcaatgaact gaatagcgga
    55861 atgctctggc cttatggcaa gtcttgggga gaaggcgggg gagaatttga tcgattggct
    55921 gcttttttga agtctggtat ccaagctgtt cgagacactc aacctaaaac aactccagta
    55981 atgctccact tagctgatgg tggcgataca ggagcattta cttggtggtt tgatgaaatc
    56041 acgagtcgag gtgtgtcatt tgatttaatt ggagtgtcgt attatccgta ttggcacggt
    56101 tcaatgaatg aacttcaaac caatatgaat gcgatcagcc aacggtatgg taaagaagtg
    56161 atcgtagttg aaacagctta tgggcataca acagcgaatg ccgatactat gccaaatgct
    56221 tttggtgaag ccgaagcagc tgcgggggga tatgaaccaa caccgacagg acaagcagag
    56281 tatttgctgg atcttgccga tcggattcag gcagtaccga ataatcgcgg ggcgggcttc
    56341 ttctattggg aacctctttg gtacaacgga aatgtgagtt gggcaacaca agcaggtatg
    56401 aattatctca gtgttcaatc cactatggga aacgaatggg acaaccaagc gatgtttgat
    56461 tttgctggaa acgccttgcc aagcttgcgt gcgtttaaac aagcaggggc gcaaataaat
    56521 ctagttaaaa atgcaagttt cgaaagcgat ggaccaacga ccagtccttc caattggcaa
    56581 acctggtttc aacaaggaac cgctaagggt acgatcaaaa cggaagcggg cacttttttt
    56641 ggggactaca aactaacttt ttggcaggat caagcatacg aggcatcagc ttatcaaaat
    56701 gttagtggca taagcaaagg aacttacaca ttgagtgcct atgtaatgtc tgggggagag
    56761 tttgatacta atcagttata tatcaaaaat tatggtggag cggaactaaa tactgcggtt
    56821 gttaaaacaa gtgaatggac aaaaattaca atcaaagaca ttccaattac aacaggtgtt
    56881 tgtgaaattg gggtttatag caaggcttca ggaaatgctt ggacgaacgt tgattttgtt
    56941 tcattggtga aacaatagac tgcggatcgt ttcgattcaa gatcggaggt tcccttcagc
    57001 cacatcgtta gcgtagaagg caggaatcga acctgcacct cgcctttgcc aaaaataacc
    57061 agaaacgatt tccagtcatt tttaccaaaa cgagtaaagc accagacttc atctacactt
    57121 tgtattatgc taaagagagt tcaacgattt cgtaagaagc aatgaaaaaa ttgcaaaaag
    57181 ttgtgcagat aacataaagt ttgtttaaga aagggtaacc ttagaattcc gtcgtgaata
    57241 tgatttgagc acttagatgg atagaaaaaa gttctcggaa aacagttcgt ttttcgagaa
    57301 cttcttttta tgataagaat gaaacaaatt aacttatatt atagtctctt ttggtaggga
    57361 accatcttat ttttaatgaa aatcaagcat tttagctatt gaagaatgtt gatttatagg
    57421 gattccccct ccatattatg ttggctcttt attcccactc tgttttcaac gtaaagtgta
    57481 taaaacagaa tgcgatacta tcaagggagt taaaacaata tacagaacag taaaacacta
    57541 taaataaaaa taaaagtgca ataaaagtgc aatttttgca cctaatcata ctctgtttat
    57601 atatgaaaac tagattctga atccaatatt tggttaacga gaggcgttcg aatttgaacg
    57661 tcttttatat attactttca aataaatatg aggtagaata ctatctattt tctttttaac
    57721 ccaattgtta taatggagag tgtaaaatat tttgtgtaaa tagaaaaaag gaagtccctt
    57781 ctgtagaata gagttaccac aacacattca cagaagagag gacttcccta tgaacgattt
    57841 tactacagaa attctaaaga ctctagcgaa caaaggcgat ttgaatgaat tattccgtgt
    57901 ccatttggag aaagcagtca atacgcttct caaaacggag ttaacggctt tcctagatta
    57961 cgaaaagtat gatcgcattg gttttaacac gggtaattct cgtaacggct cctatgaccg
    58021 tacggtcaag accgagtatg gggaacttca tctccagatt ccgcgcgacc gcaatggtga
    58081 gttcaagcaa cagactgttc ctgcttatag acggacgaat gacacgttag aggagaccgt
    58141 cattcacctc ttccgaaaag gtattaccat gtcggaaatc gcagacttga ttgagaaaat
    58201 gtatgggcat tactacacgc cccaaaccat gtccaatata acaaaatcat ttacagaaga
    58261 ggtaacggcg tttaatgggc gggagcttca tgaccgttat gctgctattt atatggacgc
    58321 aacgtatatt ccgttaaagc ggaaaaccgt cgccaaggaa gctattcata tcgcagttgg
    58381 cattcgcccg gacggatcaa aggaagtatt gagctatgcg attgcaccga ctgaatccat
    58441 cacgatttgg gaggaaattt tattggacct tcaagagcgc ggtttgaaaa atgtcctcct
    58501 gttcatcacg gatggcttaa aggggatggt aggagcgatt agtcggttct atcccaaagc
    58561 tcgttttcaa cattgttgtg tacacgtttc ccgtaatatc agtcataaag tgcgtgtcga
    58621 tgatcgtaag gaagtctgtg atgattttaa aatggtgtat caagcctcat ctaaagaggt
    58681 ggcgttggaa gcacgtggta cttttgcgga aaaatggaaa accagctatc caaaagtggt
    58741 tgaatcgatt ctttcgaacg atcacttgct cactttctat gatttcccct tggccatacg
    58801 caagagtatt tattctacga acttgattga atcctttaat aaacaaatca agaaatacag
    58861 ccaccgcaag gaacagttcc aaaatgaaga gtcgatggaa cgtttcttag tctcgtcttt
    58921 tgatacttac aaccaaaaat tcctaggtcg cagtcataaa ggtttccaac aggccgaagg
    58981 cgagctcgaa caaatgctaa gccaactgat tgagaattag aaacaatctg cagtagggaa
    59041 gaatcattta cacaaaatta ttgacgctcc cttataatga gaacttttac taacataatt
    59101 tatgataaac ttactatata atcatattaa ttaaatagtt aggagatctg cttatgttta
    59161 tatctactct tcaaattcga aattttagaa attatgaatc cgaaatcttt cgattcgata
    59221 atgagacaaa tactattata ggtgagaatg attcagggaa aaccaatgct cttactgcat
    59281 tgagaatctt attagatgat agttattact atagtagtaa aacactaaaa gaatcagatt
    59341 tttttcatgg aattcaaaat gggtggcaag ggcattggat tattatctct gcgacatttg
    59401 aaggaatcag cgaagaagaa tttgacaatg agatttgtgc ttccatttct ttaaattctg
    59461 aaagtcaaac aatcttagaa gaattgattt caaatgcaga taaaggtgta ggtagtattt
    59521 ctctatttat tagacctaac aaagctatta gaaagcaatt atttgatatt tccactgaat
    59581 tagactctca tcaatttaac gaatttagaa attctattcg tctatccgac tatgaatttt
    59641 actacacatc taaatcaaat ctaaatttct gtatcaatga aaattatgat aaattggtag
    59701 gaagactcaa tgacaatata gctagtaatc ctgaagaaga cgatgaagct ctgttgggct
    59761 caagaattga catgtcagat attttcaagc atatttcggt tgtttatgtt gacgctcttc
    59821 gagatgttct tagagaaatg aaaaacaatc gaaacccagt caaaagaatc atggaaacaa
    59881 ttgaatcaaa aatatcatca gataatgttg agtcattaaa aacaattata cagcaattaa
    59941 atgagactat taccagtgtt cctgaaatta ggaaaattgg cgaaaatatt aatcggcaac
    60001 taaatagcat aattggttca gtgtattctc ctaatcttct tctttcctca actatgtcag
    60061 atgatatggg ttctttagca aaatttcttt caatgaagcc agaacaaaat atcgacttag
    60121 acttactagg gttaggacat ctaaatatga tttatttagc tttgaaaata gtcgaatttg
    60181 aagcgtgtcg ttcaagagaa ctacttaata ttatgttgat tgaagaacca gaagctcata
    60241 ttcatcatca tattcaaaaa actctgttcg aaggattaaa tcttcaaaaa aactatactc
    60301 agattctcat gaccacacat tctgtacatt tagctgaagt gtctgaaata tctcggatga
    60361 atgtattaaa atcgtttaat ggcaaatcta tcgttatgaa tccagcaaat aatctgaact
    60421 catttgctaa agaaaagtta aaaaagaaca atctaaatct aataaacgca gtagagagat
    60481 atttagatgt taaaagaaat ggattgcttt tttctaaagg tgttatctta gttgaaggag
    60541 atgctgaaga aatacttatt cctcaaatag taaaaaaatt atttggtata aacttagacg
    60601 aacttggaat aggtttgatt aatgttggta gtacttcgtt tgaatatatc gctagcttgt
    60661 ttgacgatga tagaatacag agaaagtgtg ctattgtaac tgatttagat gaacaggcaa
    60721 tcccatcaga acatcgattg tataaaagca ctgcacaaga gaaaggtcaa gcaagaaaag
    60781 aaaaattatc ctcccttttt aatgaaaaca attgggttaa ttgtttttat gctaatacaa
    60841 catttgaaat tgagttttta gatgtgaata aagaaaatat tctaacttat gtcagtccaa
    60901 ttatagatga cgcattcaaa gataaaaaaa caataactgc ttataaagaa gaaatacaaa
    60961 gtgaacaata tttagaaaga aatttagcga tgttaaaact agccaatcat gttggtaagg
    61021 ggtggtttgc aattgagtta ggtgaaaaaa ttgacttttt aatcaaaatt cctaagtata
    61081 ttcttaatgc tattgctttt gcatgtcagg aaatagtaga tctctcaatt tataaaaaaa
    61141 ttctactcca tacaatcgac ttgtacgagg aaactacaga attgtcagct ttatcagcta
    61201 gtttaaaaac aagtgataca gctgatttga atatagcaat aatttcttta ttagagtact
    61261 ttggtaaaga tgaggatgtt gtgtatctaa tcaatcagat agaaaattac acaaaaatac
    61321 tttatgctga ggtttcaaaa tgacaaatat cttcgaaaaa atcgtaaatg atttaaattt
    61381 agaacaaaaa gatgttgtgg aaagtgaaga taacctttat gtaaatgcat gtcctgggag
    61441 tgggaaaaca agggtactta caaggaaaat tgcttaccaa gcaattaaac acgatggatc
    61501 actaaaaaga ataattgcta tcacatacac taatagagct gctgaagaaa ttaaggaacg
    61561 cctaagttta cttagtatag atgatgatat taatatttgg gtggggacaa tacatcagtt
    61621 ttgtcttgaa tttattattt atccttttaa aatgaatctc tcaagagtat caaaaggatt
    61681 tacaattatt gatgattata ctcaaagagc ttacgtcagc caaattaata atatgctgaa
    61741 tttaaatctc aaaacgtatg aactgaacaa aattgatttg tcactttctc atgattttaa
    61801 aattaatgaa gttcagtata ctcaagtttc tgaaatgtat cacactatgt tggaaaaaaa
    61861 taaagaaatt gattttgata tgattttact agtagcgtat aaaattttaa ctgtaaacag
    61921 taacgttgca cgtaatattg ctagtaatat aagggcgatt tatgtggatg aatttcaaga
    61981 tactagagaa ttacaataca atgtaatagc taaattactt caaaacaacc ctcaaattca
    62041 gtcaatgttt gttggagata ttgaccaagc aatttatgga tcattagatg gtatagctaa
    62101 atcagttgaa gaactagaaa tgctaactag tcacactttt caatcaaaga cgctacatgg
    62161 ctgttacagg tctaatcaga gattagtaga cttctactct aattttcaga gttgtcctta
    62221 cgagattgaa agcagaggga ataataaaaa cgaccgtggt tttataagtt atgattgcaa
    62281 agttactaag gaggatttac ccaacataat aaaaaatata ataaaggaaa agattgaaag
    62341 cggcattcat gaaaaagata tttgtgtact tgctcctcaa cactatcctc tgttttcact
    62401 gggtgagtat ttaaagaaag aattaccgta ttgcaatttt gatgctataa atatatcacc
    62461 aattaaggta aataatcata gtttattttt caagttagca attttgtact ttactgaatc
    62521 aggtgaaaag gttcgaagaa gaaagctaat tgcaaacgat attttaatta tattaaaaaa
    62581 tgaatttgga atagaagtta aagattattt tattgactta gatttattac agctaataaa
    62641 cagtgtgaaa agaatgtata gtggagacga caacggtgtt gatttataca aatttgttac
    62701 caaacatata tttgttaatc ttaatattga cgagaaaaat tacccgtcta tttttaagca
    62761 ctatctattt tttattaacg aagtagaaga tcggataaaa aataattcat tatctagtag
    62821 tgtatctagt tttaagaaga tgtttaaatc tcgagatggt atcacactta ctacagcaca
    62881 taaagttaaa ggaaatgagt atgatactgt tatcgctatt aatcttctaa acgggaaaat
    62941 tcctcattgg aatgaaattt ttaatgtttc tgataaagga attagttcag cgagaaaact
    63001 actatacgta atttgttcaa gagcaaaaaa taatttattt cttttctcag aggtgggtta
    63061 ttttacgagt aaaggagact tgctttatcc cactcaatta ttagataaaa tagaatttga
    63121 ttataatatt taaaatacct aggtagtcgt tgtttt
//
LOCUS       DAYNVV010000008        60148 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.008, whole genome shotgun sequence.
ACCESSION   DAYNVV010000008 DAYNVV010000000
VERSION     DAYNVV010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 60148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.008"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..561)
                     /locus_tag="ACGXWR_000659"
     CDS             complement(<1..561)
                     /locus_tag="ACGXWR_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFK0802270.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(616..795)
                     /locus_tag="ACGXWR_000660"
     CDS             complement(616..795)
                     /locus_tag="ACGXWR_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802271.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(872..1381)
                     /locus_tag="ACGXWR_000661"
     CDS             complement(872..1381)
                     /locus_tag="ACGXWR_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802272.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(1477..1857)
                     /locus_tag="ACGXWR_000662"
     CDS             complement(1477..1857)
                     /locus_tag="ACGXWR_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFK0802273.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            2187..2936
                     /gene="pnuC"
                     /locus_tag="ACGXWR_000663"
     CDS             2187..2936
                     /gene="pnuC"
                     /locus_tag="ACGXWR_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HFK0802274.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(3120..4397)
                     /locus_tag="ACGXWR_000664"
     CDS             complement(3120..4397)
                     /locus_tag="ACGXWR_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802275.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(4476..5120)
                     /gene="pcp"
                     /locus_tag="ACGXWR_000665"
     CDS             complement(4476..5120)
                     /gene="pcp"
                     /locus_tag="ACGXWR_000665"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HFK0802276.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(5319..6263)
                     /locus_tag="ACGXWR_000666"
     CDS             complement(5319..6263)
                     /locus_tag="ACGXWR_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HFK0802277.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(6265..6951)
                     /locus_tag="ACGXWR_000667"
     CDS             complement(6265..6951)
                     /locus_tag="ACGXWR_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HFK0802278.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            7425..7745
                     /locus_tag="ACGXWR_000668"
     CDS             7425..7745
                     /locus_tag="ACGXWR_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HFK0802279.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            7899..8804
                     /locus_tag="ACGXWR_000669"
     CDS             7899..8804
                     /locus_tag="ACGXWR_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802280.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            8801..9574
                     /locus_tag="ACGXWR_000670"
     CDS             8801..9574
                     /locus_tag="ACGXWR_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFK0802281.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(9755..11179)
                     /locus_tag="ACGXWR_000671"
     CDS             complement(9755..11179)
                     /locus_tag="ACGXWR_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFK0802282.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            11390..11836
                     /gene="nrdI"
                     /locus_tag="ACGXWR_000672"
     CDS             11390..11836
                     /gene="nrdI"
                     /locus_tag="ACGXWR_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFK0802283.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(11901..13883)
                     /locus_tag="ACGXWR_000673"
     CDS             complement(11901..13883)
                     /locus_tag="ACGXWR_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFK0802284.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(13897..14793)
                     /gene="murQ"
                     /locus_tag="ACGXWR_000674"
     CDS             complement(13897..14793)
                     /gene="murQ"
                     /locus_tag="ACGXWR_000674"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFK0802285.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(14796..15857)
                     /locus_tag="ACGXWR_000675"
     CDS             complement(14796..15857)
                     /locus_tag="ACGXWR_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFK0802286.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(16068..16595)
                     /locus_tag="ACGXWR_000676"
     CDS             complement(16068..16595)
                     /locus_tag="ACGXWR_000676"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFK0802287.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLAEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(16662..18164)
                     /gene="eat(A)"
                     /locus_tag="ACGXWR_000677"
     CDS             complement(16662..18164)
                     /gene="eat(A)"
                     /locus_tag="ACGXWR_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFK0802288.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(18422..19543)
                     /locus_tag="ACGXWR_000678"
     CDS             complement(18422..19543)
                     /locus_tag="ACGXWR_000678"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFK0802289.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            19669..20610
                     /locus_tag="ACGXWR_000679"
     CDS             19669..20610
                     /locus_tag="ACGXWR_000679"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFK0802290.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(20760..21656)
                     /locus_tag="ACGXWR_000680"
     CDS             complement(20760..21656)
                     /locus_tag="ACGXWR_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFK0802291.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFNMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTSFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            21925..23265
                     /locus_tag="ACGXWR_000681"
     CDS             21925..23265
                     /locus_tag="ACGXWR_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFK0802292.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            23483..23926
                     /locus_tag="ACGXWR_000682"
     CDS             23483..23926
                     /locus_tag="ACGXWR_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HFK0802293.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(24191..25609)
                     /gene="nhaC"
                     /locus_tag="ACGXWR_000683"
     CDS             complement(24191..25609)
                     /gene="nhaC"
                     /locus_tag="ACGXWR_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFK0802294.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPKLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(26012..27235)
                     /locus_tag="ACGXWR_000684"
     CDS             complement(26012..27235)
                     /locus_tag="ACGXWR_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFK0802295.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKEGFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVEQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(27266..28105)
                     /locus_tag="ACGXWR_000685"
     CDS             complement(27266..28105)
                     /locus_tag="ACGXWR_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFK0802296.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETTVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNAALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDEKNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(28122..28802)
                     /locus_tag="ACGXWR_000686"
     CDS             complement(28122..28802)
                     /locus_tag="ACGXWR_000686"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFK0802297.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(28804..29877)
                     /locus_tag="ACGXWR_000687"
     CDS             complement(28804..29877)
                     /locus_tag="ACGXWR_000687"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFK0802298.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IIEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRQKALDYLIKS
                     GVKINILQKNELDSRIKVIEGGR"
     misc_binding    complement(29933..30171)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(30213..30446)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(30523..31194)
                     /locus_tag="ACGXWR_000688"
     CDS             complement(30523..31194)
                     /locus_tag="ACGXWR_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFK0802299.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYFDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLD
                     KKTEK"
     gene            complement(31281..33929)
                     /gene="mgtA"
                     /locus_tag="ACGXWR_000689"
     CDS             complement(31281..33929)
                     /gene="mgtA"
                     /locus_tag="ACGXWR_000689"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HFK0802300.1"
                     /translation="MEKKKDTQKIYAAFAGKTKQELFELFHASANGLTEEQIERSREN
                     YGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPGDKDLFGVAII
                     FTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEEIVCGDLVRLS
                     AGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSYENLVFMGSNV
                     ISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKFMSLMAPAVIV
                     INGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGTVIKNLNAIQN
                     FGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQTGLKNLLDVAI
                     IDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGAIEEMLNISKF
                     IDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFSVKDESDMVLI
                     GYLTFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLEINELVTGEKI
                     SEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGINDAPAMKVADI
                     GISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKATASSNFGNMFS
                     VLIASMFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKWNASSIGKFMV
                     YFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQQVIFIALFHAGWFVESLWTQT
                     LVLHALRTPKVPFIQSNVTFAMFVITTLGIIVGSVLPFTSFGAELGLMPLPGNYWLWL
                     FATVIAYLALVTAVKKIYIHRFQELL"
     regulatory      complement(34271..34445)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            34618..35055
                     /gene="ndk"
                     /locus_tag="ACGXWR_000690"
     CDS             34618..35055
                     /gene="ndk"
                     /locus_tag="ACGXWR_000690"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HFK0802301.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAVDAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(35077..35943)
                     /locus_tag="ACGXWR_000691"
     CDS             complement(35077..35943)
                     /locus_tag="ACGXWR_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFK0802302.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICSKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLSLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEKKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(36103..38196)
                     /locus_tag="ACGXWR_000692"
     CDS             complement(36103..38196)
                     /locus_tag="ACGXWR_000692"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFK0802303.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWMKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVLYWLDIATFIGILVWLTIKKIPIKSQPVSKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFSESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSAIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWNEFDN
                     AQMQRVPLMIHIPGYTKGSVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSPQHD
                     QVVAFRNGNFVTPKYTILGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKSALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNIAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKDNQ"
     gene            complement(38672..39295)
                     /locus_tag="ACGXWR_000693"
     CDS             complement(38672..39295)
                     /locus_tag="ACGXWR_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802304.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(39454..40851)
                     /locus_tag="ACGXWR_000694"
     CDS             complement(39454..40851)
                     /locus_tag="ACGXWR_000694"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFK0802305.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHPEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(40883..41854)
                     /locus_tag="ACGXWR_000695"
     CDS             complement(40883..41854)
                     /locus_tag="ACGXWR_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFK0802306.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKELLEKGVTAIFVSNYNMSIGAIECFNQEGIRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGEQAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            42228..42653
                     /locus_tag="ACGXWR_000696"
     CDS             42228..42653
                     /locus_tag="ACGXWR_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802307.1"
                     /translation="MKKLIVLFILSAGLLTLTGCNLFGGSDQSSDETTDSSVLKAEKA
                     DITNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQETDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKEATITFTKIGNYRLKDEDGNIYSL"
     gene            complement(43141..43842)
                     /locus_tag="ACGXWR_000697"
     CDS             complement(43141..43842)
                     /locus_tag="ACGXWR_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFK0802308.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIHQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(43858..44298)
                     /locus_tag="ACGXWR_000698"
     CDS             complement(43858..44298)
                     /locus_tag="ACGXWR_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFK0802309.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(44298..44873)
                     /locus_tag="ACGXWR_000699"
     CDS             complement(44298..44873)
                     /locus_tag="ACGXWR_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HFK0802310.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            45113..45322
                     /locus_tag="ACGXWR_000700"
     CDS             45113..45322
                     /locus_tag="ACGXWR_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit beta"
                     /protein_id="HFK0802311.1"
                     /translation="MYYFKQQILVSFINEKIILFSCYVSLINDVSLNKKADELNDQNL
                     IIFVHQLLLKIFLLTINSWICKNIT"
     gene            complement(45720..46232)
                     /locus_tag="ACGXWR_000701"
                     /pseudo
     CDS             complement(45720..46232)
                     /locus_tag="ACGXWR_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014566402.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(46358..47059)
                     /locus_tag="ACGXWR_000702"
     CDS             complement(46358..47059)
                     /locus_tag="ACGXWR_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFK0802312.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(47167..48610)
                     /locus_tag="ACGXWR_000703"
                     /pseudo
     CDS             complement(47167..48610)
                     /locus_tag="ACGXWR_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            complement(48624..50490)
                     /locus_tag="ACGXWR_000704"
                     /pseudo
     CDS             complement(48624..50490)
                     /locus_tag="ACGXWR_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
     gene            complement(50611..51462)
                     /gene="licT"
                     /locus_tag="ACGXWR_000705"
     CDS             complement(50611..51462)
                     /gene="licT"
                     /locus_tag="ACGXWR_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFK0802313.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            complement(51772..52485)
                     /locus_tag="ACGXWR_000706"
     CDS             complement(51772..52485)
                     /locus_tag="ACGXWR_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFK0802314.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(52553..52879)
                     /locus_tag="ACGXWR_000707"
     CDS             complement(52553..52879)
                     /locus_tag="ACGXWR_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFK0802315.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(53002..53229)
                     /locus_tag="ACGXWR_000708"
     CDS             complement(53002..53229)
                     /locus_tag="ACGXWR_000708"
                     /inference="COORDINATES: protein motif:HMM:NF013777.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFK0802316.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(53551..54804)
                     /locus_tag="ACGXWR_000709"
     CDS             complement(53551..54804)
                     /locus_tag="ACGXWR_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFK0802317.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            54865..55605
                     /locus_tag="ACGXWR_000710"
     CDS             54865..55605
                     /locus_tag="ACGXWR_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFK0802318.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(55691..56449)
                     /locus_tag="ACGXWR_000711"
     CDS             complement(55691..56449)
                     /locus_tag="ACGXWR_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFK0802319.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(56446..56910)
                     /locus_tag="ACGXWR_000712"
                     /pseudo
     CDS             complement(56446..56910)
                     /locus_tag="ACGXWR_000712"
                     /inference="COORDINATES: protein motif:HMM:NF023225.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
     gene            complement(56929..57426)
                     /locus_tag="ACGXWR_000713"
     CDS             complement(56929..57426)
                     /locus_tag="ACGXWR_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HFK0802320.1"
                     /translation="MILLLGFILWQTPVHASEFNFAVDFELPANQIDKNKTYINVRME
                     PGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESKSKFDETLSYDMKNLAK
                     TVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKENVSNKSTVGVVNQFSQV
                     KAILI"
     gene            complement(57494..>60148)
                     /locus_tag="ACGXWR_000714"
     CDS             complement(57494..>60148)
                     /locus_tag="ACGXWR_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HFK0802321.1"
                     /translation="GTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLD
                     LYDGSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQL
                     YGPYLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGN
                     VMFEVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRL
                     QGDSSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRS
                     SAVRFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSAD
                     FTVTGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLN
                     VDLESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEK
                     DPDYFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESL
                     RVPTNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQT
                     DENEGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKT
                     TVDVIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSI
                     PENQLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPA
                     TKIVVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIK
                     LSQPFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAF
                     KLVLTKENQIAGNYSAEITWTLADAPTE"
BASE COUNT        17250 a        12651 c        10341 g        19906 t
ORIGIN      
        1 gatattcttt tgcatatgat cataaagatg accactgatc atccgctgac cgacaacttt
       61 gaagtcatgg cgttcgtata attttttagc ctttggattt ttttcatcca cacttagacc
      121 gatgacggag cgattagctt tcttcgccaa tttaggtaat gcttctaata atcgcgaacc
      181 gatgccttgt cctctaaaat cttctgatac actgatagag tccaaatacc attcgttggg
      241 aaacgtttct ttatcaatga acaaacgtgt agacgcatct agctgatatt tctctaagat
      301 aggtaccagt ggctgatcga tgattgattc ttcttcatct gtataaccgt aagcaactcc
      361 tgcaacttta ccgtctattt cttctacgat acctcgtgaa taactgtaac gataatttgg
      421 atcagtgatt gcttcttcta aaatctctaa agtcttttgt tcccctgtct gcttcaaaaa
      481 tggcagttcc atatctttta gaatcactaa gatcaatggg gcgatttctg gagcatcttc
      541 ttttctcgca aaacgaatca tagtttcctc tccttttctc cattctaaca tgcagaaaaa
      601 gaaatcgcaa aatcgttatt ttaaaaaatc ttcaatcttt tcagtaatga aataaccatg
      661 agtaacgatt cttgccgctt cagttcggca ataagggcag acgactggca tttctttatc
      721 attatgttcg actacattat tgacttcttc gtatgcaaat ttttttccgc aattagggca
      781 tttcattttt tccatgttat ctcaacttcc tttcatcttt actctcttag cttactctta
      841 tattgtaaaa aagagaagca atatccttct tctatgcaga tatccatacc tgacggtcct
      901 gttctccatc tattaatcgg actttataat aaggacgttc atctttgact agaagtgtcc
      961 actctttcac ttttgctttt ttcccgtagt agctgactgc ttccttcatc gctgcttgcg
     1021 gttgtttgaa ctcttccgtt ttttctatat caaaaagatg ttctgcggcc ttttccgtgt
     1081 catttcgtac ggttgttttc ccagtggatg gattgactgc tatgacttgt ccttcacaaa
     1141 aaaactggta ttcatatgtt gcattcgtag gattctccaa atctttttca actgcaaaat
     1201 gaatagcaga tatgttatgt tcttttgttt cgttttttac gattgctgct gcttttttca
     1261 atgagatccg atattcctgg tcactaatat catccatgtg aaaagcggca ttgagcagtc
     1321 ccgtcatacc ggtaatccct attacgatga gggcagcaac accaaacatc atttttttca
     1381 ttcttcattc tcctgtttct tttttttaaa gaatatcaag aaatgaacga atgaaaaatc
     1441 gaatgaaacg aaaaaaaagt gacaattttg ttatctttat tcgtgcagtt ctaatggcaa
     1501 tccgtctgga tcaaagaaaa acgtcatttt ttttcctgta aaggtatctt ctctaatcgg
     1561 ttctgattcg atccctaagg actgcaattc tgcaattgtt tcttcaatat cgtctacttt
     1621 gaaagcaaga tgacgcaagc cacaagcttc tggatagttt ggtcgttgtg gcgcattagc
     1681 aattccaaaa atctccaatt cagcacttcc tagtttcaga tctaatttat agtcatctcg
     1741 ttctttgcgg taattttctc tgattacttc aaatcctaat ttattaacat aaaaatcacg
     1801 tgatttctga taatctgaaa caatgatggc tatatgatgg atcgttgtaa ggttcatatg
     1861 agcactccta ttcttcgttt aagctcggat ctatattaat ctccagttcc attgtaaatg
     1921 tgtcagattg aaaaaaatag ctgtttttcc tttttataag aaaaaaggca aaaaaaacag
     1981 aaagtaggtc ctccaagaca ctcttcctgt tcccaatata ataaatgaaa gtaagaaatt
     2041 atattttcaa gaaaacaaac agaaaattat cataacacaa attatttata attgaaagac
     2101 tagttttttt tcaagaaaag catacaatag attgtgttag taaatacaga acacactaca
     2161 tttagtgtct taaggagtcc tcatacatga agtcatattt tcagttttta gctcatcagc
     2221 taaaaggctg gccgcaacaa aattattatc ttttcttttt cagtcttggc tgccaggtca
     2281 tgactcttgt caatagtccc atcacttggc tgtccgttat tacatttatc ggtaccacgc
     2341 ttggtgtatt gtgtatttta tccatcaatg cggcaaaatc agtcaacggt attttaggta
     2401 ttttgtctgc gatttgtttt attatcgttg ggttttcagc aaagaactat ttaagtatcg
     2461 gtgaacagat tgcttatatg atcacattgg atatccccgt attgttaagt aaagaatgga
     2521 atcataatat ggcttcaaaa atccgaaaat tcactggaaa aagctggttt atcgcaatca
     2581 tcagtacttt ccttgtctat cttgtttcag gattcctgat tggtcgttat acagatgatc
     2641 ctcggccgtg ggtagatgcc attgcttttt ctattagctt gactgctggt atcatcagtt
     2701 tcttgcgtta caacaaccaa tattactggt ggttagcttc agggcttgct caaatggtcc
     2761 tttggtatat ttcatttacg catggatctg caagtttggc gatgttcgtg aacagctctg
     2821 tttacttgct gaatgatgtc cttgcattta ccgtttcacc ttggtataac caaaaagaac
     2881 gtgaacgtat gcaaaaaatg gaagaagaat actacaacgc acaacaacac gcataaaaaa
     2941 actgagcgtg ggacaaaagt aaagaacact tttgtctcac gctctaaaca cgtataaacg
     3001 gcggaatcag aagcaactcc ttcggaaata agctgaaatt cacaaaaatt tgaaaagcaa
     3061 ttttcgtgaa tttcttctta tttcttggag ttaaacgctt ctgtcccagc ctctattttt
     3121 tatagtaatt ccttcagata ctttcttgcc tcatcattga aacgcagtga ttcttctaac
     3181 ttctgataat attccaacgc ttgtttctga gcttcagtaa aacgataatg ttttcctttc
     3241 catttgtcga ttgtctcttg cacatttcca gattggatat ctttcactac tagttgccat
     3301 ttttcttttg agactgtacg gtctttctta tcagcagatt gtatagcttc tcgttcttta
     3361 cgcaatactt ttaaaaaacc atttctgact atccgaggaa tgctgtcgaa gaacccttct
     3421 gtaaaaccat agcgacaata ttgcttccaa ataaatagat agatttttgg ttggatgaat
     3481 cgttggtttt tcgcaaaata ttccatctga gcagtgactt ctggtgttcg ttgacgtttt
     3541 gtctttctca acacggaaat aaatgtttca aaataagcat taggatgtac tggcacttct
     3601 tcatatacga tggattgcca atctttacgt aaaaatgcgc gatagttgat caagaattct
     3661 tctacatcct ttactaattc ttctgcaaag tcgtcaaata gttctttttt tatctgtcgc
     3721 ttttttgact gcccattgat gtgttcactt attttcttga tttcattttc caatgcttga
     3781 taatccgcta tgtaaatcgg catttctact tggcgaaatt ctgcgagccg ctgagctaat
     3841 tttatatccg gtaaatatgg ctgtttcatc cgacgatttt ggtacaagac aaaacagtat
     3901 ttttgccata gtccttcagg aaaatcgata ttcttctgct taagccataa taattcgtct
     3961 aaggccagat caacttttgt cattccctga tggatcgaag ctgccactgt cggagagaca
     4021 tgcaggtgat cggcaaagtg gttgatgcct agttttagga tctttccggt ttttggcgat
     4081 ttaacgatgt attgcacttt taattctcta ccacactcac aatacaattt ttgctggctt
     4141 cgttttgttc gaaaaaacgg attgatcttg aagtcagaaa acacccaatc tgttgcagct
     4201 aaataatgtt cttccataaa acgagagctg attagatatc ggcggtgctt atcgactagt
     4261 tcccgctgtt ttttcgttaa ttttgcatag atctcccaac gttgactgct tgtgtattgt
     4321 ttagaaattt tgatgggata gcttttgctg atttcttttg gaaaccattc ttcaaagacg
     4381 gattgccatt cttccacggc tgtttctttc ctttctaatt acaaaaagct ggctactaac
     4441 ataacgttag caaccagcca gtgtttcttg ctaaattagt gagttgttcc ggcatttccg
     4501 gaaatatctt ctttattttc tactgctgct tcaactgcat aagtcaaaga agaagcaatg
     4561 tcttctaaag acatagaagg cgtacccact ggacgatcga tcacttgatc gggtgagaat
     4621 ggcacgtgga tgaacccacc tcgaattgcc gggaattgtg tttcgatcaa atgaagcaaa
     4681 cgatacatga tatcattgca gacaaatgtt cctgctgtat aagagatgta cgctggtaga
     4741 ccatgatctt gtacattttt tgtcattgct ttgattggca atgaggtaaa gtaagcggct
     4801 ggaccgtttt cttctaaagc cgtatcgaat ggctgatttc cttcattatc agggattctt
     4861 gcttctgcta gattgattgc gacacgttcg aacgagactg ctgaccgccc acctgcttgt
     4921 ccgacacaga tcacgacatc tggttggtgc tgttggatgg cttctttgac tacttgactg
     4981 cttttttcga atacggtcgg tacttccact ttgatgattt cagcaccgct gatttcatct
     5041 ggcatttttt ttactgcttc ataggctgga ttcactttgt ccccaccaaa tggatcaaaa
     5101 cctgttacta gtactttcat ctgttgttcc tccgtccgat tgatttaaca tatggttatc
     5161 ttttatcata ccattttcct tgaacagcgt aaataaagga aacaatagtt taaataacat
     5221 aacagatcaa acttaatata ttcttataaa aaaatagtgt tccactacaa tgttagaaga
     5281 ggttgcgaca attattctgt cacaacccct ctcttctatt atttaaatag aatcatataa
     5341 gcaatttgga aaactagcat aaataacgca ataaacaact ggtttttgat cactccgtat
     5401 ttgtctttca tctccagcat cgctacaggc acgatattga agttagcagc catcggtgtc
     5461 agcagggtcc cacaaaaacc gcaagtcaat gcaaccattc ctattaacgc tggattcgct
     5521 ccatgactaa atacgaatgg tgcaccgatc ccaaccgtca tcacggtgat ggccgcaaat
     5581 gcattcccca tgattaccgt aaatatcacc atgccaagag cgtaaatgat gatgccgatg
     5641 ttcacatttc cttctggaac gatcgtacct actgcattgg aaatcactgt cccaactcca
     5701 gcgcttgtaa ataccgcacc tagagaagct aaaagcattg gcaacatgct taacggccct
     5761 actgtgccca gcatatctgc tgcatcatct aaaaatgtac ttggtcgatt atctcgagaa
     5821 aagaacatca agattagcat ggctgcaaaa acaccgacgc ccacgccgac taaagcacct
     5881 aaattggtaa atagagcaaa caagatcgca aagacaccga tactcaaagc tggaataaaa
     5941 attttcattc ctagtttgtc tgacattttt tccatatatt cttttgatgg aagccggctt
     6001 tctcctttgc tgactttctt agcaattgct ggtatggtca tcgcaaagat caagccaccg
     6061 ttcacgattg ccggaagcca tcttcctcct gcaataacta cccctaagac cgtccagaaa
     6121 aaggctgacc cataacgatg aggattggtt ttatctgtta aatttcttac tccagtgtaa
     6181 atcaatacga gtcccatcac gatataaagg atctccagta atttatcgcc taataaaata
     6241 tcaggatttg taaaaaagtc catcttattg cccctttcct ggataatatt tcttcgctaa
     6301 tttcttttct ttaagataga agtagacact tgccacaact aaagccgtga tagccactgg
     6361 aacttccact aaagcaagct gtcccaatgt tacgtcatat cctagatctt tcagtgttga
     6421 ttggactagc aacgcccctg ctcctccgat gaatagtact tggccaaaga accagcagac
     6481 attttccata gctgaagcca taccttttag ttcttcttca tgcttaggat ggacttctaa
     6541 cccttttgat tcgatggtcc ccaatgccat cggtaaaatg attggacgaa caaatccagc
     6601 aactccacca aaactcacgt taaaagccgc aaagatcatt cgaaagatcc cataaatatc
     6661 tacaatcata ccagcagata ctttcttgaa tcgcttgatc aaggaagccg ctgattcttt
     6721 cagaccattt ctttcaagcg ttcctgttgc caacataatg atgataaaaa tcgccatccc
     6781 gcgattgttt acaaaacttg tacctaaaag ttctaacatt ccttgaatgc caagaccgcc
     6841 agtcaaagct gtaacaacta aagcaaccat tacgatcaat atcgagtcta atttaaatgc
     6901 aaacccgaga ataacaatca agacgcctaa aaggctaaga taattttcca tatattttcc
     6961 tccataaaat gacaatattt ttttaattat aaagcaaaac acataaaaaa tatagttgtt
     7021 ttctcacgaa atagacacta tttttaaata tttttcgtta tttttttatc acaaaaatta
     7081 tcttacttat tgtaaggtaa agcttttttt aatttattgc ccgataatat atagaaataa
     7141 ggtctagtta ctgttttttt taaatgatta ataaataaca acttctttct atgaaattgc
     7201 aaagcattca tcttcttttc cgctaacgat atatccgtca gtgcttggta cactttacta
     7261 aaaagtatga gattgccgat atctggatag gtgtgctata ctacagaaaa agatatacaa
     7321 tctgccaccg ggtaggataa agaggatgat cattccatta ggtctttgaa gggatgattt
     7381 tcctcttttt gtgtattttt ttatagttaa ggaggaatgt aagtatggca tggatggaat
     7441 taatcatagc aggaattttg gaagtattct ggtcaacgat gatgaaatgg agtgatggtt
     7501 tttctaaaat caattattct ttttacacag tgattggcat gattgctagt ttttactttt
     7561 tgtcaaaggc aatcaaaagt ttgccgatga gtctctctta tcctatctgg acagggattg
     7621 gcgcagttgg ttcggtcata attggtgtgg tcttgtttca tgataagctg aatctttcca
     7681 cttggttctt tgtggggatg ctactcatca gtatcattgg catcaagatt actagcggcc
     7741 actagacact tggaataagt actgatcaga aaaaataagc ctttttattt aatattcaat
     7801 ttttttatga aaaaataaga aataagtcca atgacctagc gacttctcca ctcatcaggt
     7861 gtatgcttgt actatctata gaaaaggagt gaatattttt gaaaagtctt tcggtccaag
     7921 aattatccaa gaactttggt cacaaacaag ccctcagcga tgtcagtttt agcttatccc
     7981 ctggcaaaat cgttggatta gtaggtccta atggcgctgg aaaaacaacg atcatgaaag
     8041 ctattttagg actgatccat tactcagatg gaacaatctg tattggtgaa aatgagattt
     8101 ctccctctag tcataaaggg ttggaacaag taggagcatt gatcgaatac ccgggtatct
     8161 atccattctt aacaggctat gatcatctga agttattctc tgaaaccaac gatgtatctg
     8221 ctatcgacac tatcgtgaat cagctcaaga tggaaaagta cattcacaaa aaagcgaaat
     8281 cctactcgtt gggaatgaaa caaaaattgg gaattgctct tgccttactg aaccatccgt
     8341 ctatcgttat tttagatgag ccgatgaacg gtttggatcc acaagcaaca agagatgtgc
     8401 gaaaaatcat taccgacttg gctactcagg gcacctcttt cttgatctcc agtcacttac
     8461 tcagcgagct tgaaaaaatg gtcgatgagc tgatcctgat caatcaagga aagatcatca
     8521 aacaatgtac aatggctgaa ttgaaccaaa cagcgcaaga tttcatcgtt atctctacaa
     8581 caaatgatct agctgctcga acgatcttga cagaagctgg atatactttg gaagatcctg
     8641 ataaaatcaa gcttttaaaa gaaaacgaag aattattagg aaccgtgatc cagctattgt
     8701 ctgcacaaaa tatccatgtg acagacgtcc agcatctgac gaatgatttg gaatcttctc
     8761 tattggaaat tctggattca gtaaaggggg aagaagaaaa atgacattgc ttgtaaaaca
     8821 agaattattt aaattgatca agaaaaagtc aactgctgtt ttatctgttc tattagttgt
     8881 tttgctcata ggaacagcac ttctagccaa aaaatacacg acgatcattg atccagttga
     8941 aatgactgct cagcttttta gtgccacatc ttggattgtc tttatcatga ttgcagctgc
     9001 aagcacgatc atttcgatgg aagcacaata tggtacattg aaaaatctcc tttatcgaaa
     9061 gtattctcga ggagaaatat tagtaagcaa atggatcaca ttagttattt attctgttta
     9121 tttatacctt ttagctatta ttgtcactgt gttgatgaaa ctgattcttt tcccttcgat
     9181 ttccttcacg gagaaggttt ctactggtca aacactgatc caaagcttgt tcacttatac
     9241 tttgggtagt tatatcggtt tatggctgat tttaagttta gtgttgatga ttgcttgctt
     9301 tatcaatagt tccggtgcat ccatctcagc aggaatcgtc ttttattttg cttcgtcaat
     9361 catatctggt atccttattg cactcatcca aaaatgggag tggatcaaat ggaatccgat
     9421 cagtatgttg aatctgcaaa accaaattgg aaacgaagag atcatgaagc aattgactca
     9481 tctttctact aatcaaatgc tattcggtaa tttagcttac atcgttttgt tcttagcatt
     9541 aggatatctc gtatttaagc gaaaaaatgt atgatgactc atcaaaaaag aggctgtgaa
     9601 agagacgttc agccttattg ccgattggct gtctcttaaa caccgtttat tctgaaaaag
     9661 gagctgtgac aacatttgtg tcacagctcc tttcctagta tgtttttgaa taaacgacag
     9721 gctcacaacc tctctttata cttcttttat acttctatac gtgaagcatc ccagtggcaa
     9781 ataaaaccat tgcaatcact ccgaccatcg tcacacctat aagtaaaatc ttatctaagt
     9841 ggatatgttg tacaggctcg ttttgctcct tacgtgcttt gaggtaaaaa taaatgcctg
     9901 gcaagaaaag aacaagaaca agcattactt cattaaaggc tacgactagc atagcccata
     9961 cttgaaaggc acttgctaaa agccctacta aaaattggac ccattctttc cgctgataag
    10021 aaagtttcat ttggtacaat cctaagaaaa gccacgtgaa gaaaatagct gctgtaccaa
    10081 gtgtgtaagc aaagttataa gcactgtcag tgaataataa tgaaagtaaa aagacattcg
    10141 tacataacgt cgtcaatacg atagcataag ttggtgcccc atttttgttg agttttcccc
    10201 atgctttagg caaaagtccg tcttcagcca tgtttcccat tgtttcaatc ggtaagatcg
    10261 tccatgagag ccaaacacca actaaagaaa tgatcaaacc gccgttgatc acgactgctc
    10321 cccatttacc aaccatcatt tcaaacacat agcccatagc aggctgcgcc ttgatcgttt
    10381 gcagctgatt catcgtcatt gtcccatatg gaagcatgga aaccaagacg taaataataa
    10441 tcaagccgaa tatccctaga atcgttgctt tcccaacatc tgattgtttt tttgctcgtg
    10501 aacctacgac agaggctcct tcaataccaa caaataccca aagcatcacc atgatgcaac
    10561 tcaatacttg actggaaaac gggatcggct gtccattcgc attcaatata atgtcgctag
    10621 aaaagttatc aatgaattgt tggatcgaaa acgtgctgat agctactaca ataaataaaa
    10681 ataatggcac taatttacag aatgtgacga tagcattgac gaaactagca ttttcgactc
    10741 cccgattcac tagccatgca tatccccata aaaagactgt actcatcacg atcgatgcca
    10801 gattttgccc accttcaaat actgggaaga aatatcctaa tgcgctcatc aacaatgttg
    10861 caaaagctac gttgcctaac cagcatgtga gccagtaacc ccaaccgctg ataaaaccag
    10921 cgaaacggcc aaaaccttct tctgcgtaac taaagatccc gccttttaaa tctggacgtt
    10981 ttttattgat attattgatc gacaaggaga gcatcaacat tgctgttcct acgagtaccc
    11041 aactgaaaat agctgggccg ccagccgatc cggagatgtc cgtcataata ccaaatacgc
    11101 cacctccaat cgctgaacca attactaagg cagcaagtgg aattaaacca attccttttt
    11161 tctgttgctc tgtatccatg taagcatcct ccaaaataaa accgctttta tcaaaaagta
    11221 taacaaacct tttttatttt tacttaatta ataaaaactt taatagaaat ataattctac
    11281 cggctttttt ctcattatac aagcaaagcg cctagtccct ttccaaatta caccaccaaa
    11341 aaacttaaaa aagatgctat actaaaagga aagaattgga ggatgatcca tgaacatttt
    11401 atatatatcg atttcaggaa atacgcgtgc ctttgccaaa catctagcag aatatgctga
    11461 aaaaatgcat gcagaagatc ctgtcaatcc tgaagttact ttaaaagaaa tccatgaaaa
    11521 tagtgatttt acgaaagaaa cagaaccatt ttttactttc gttcctactt atttagacgg
    11581 cggaaatggt ttagataacg gtgatacaga aatcttgacc gaaacgatgc gtgaatatct
    11641 ggaacatgaa gacaatcata aactttgtct tggtgtagtc ggtagcggaa ataaaaactt
    11701 caataatcag tattgtctaa cagccaaaca atatgcacaa acatttggct ttcctttctt
    11761 ggcagattat gaattacggg gaacaccatc tgatgtgaca cgaatttatc agattttagc
    11821 agaaaacaat aaataataaa aaagaagaag ctgaaaaata gatttcagtt tcttctttcg
    11881 tttctattgt ttctatcata ttaagctttg acatccatca caggtgcttt tgcttttgct
    11941 ttacctgttt tttccaagac aaagtttttt acacgatcca tattggttac caagacgatc
    12001 atggatgttt ctttgcctgc tgctttgatc gcttctaagt cagcttctgc tacaagcgta
    12061 tcaggtgtca cttgctgccc ttctgttact ttcacatcaa atggcgtacc gcctaagtca
    12121 actgtgttga ttcccatatg aagcaagatt tctaaaccat ttggcgttgt gatcccaata
    12181 gcgtgtttcg ttgggaagac agagctgact accccagtaa ctggagaata gatatgtccg
    12241 ttttctggtt ctacaaagta gccttcaccc atcatctttt gtgcaaaaac tggatcactt
    12301 gctttatcta aagaaacaac tgttccgtca gcaactgatg agaggatagt cacactttca
    12361 gctgaagttt gaggtactac tttttcaggc acttcattta ctgtggctgt ttcagtcgct
    12421 aattcttctt tttctaaacg gtctttagga ataccgaaga agaatgtagc aacgaagcca
    12481 ccagcataag ctgccaataa tccaaggatg tagcctaacc atttaccgtc agagatcaat
    12541 gggatcaaag cggctcctga aggtccaata gcgatagccc cgacatttcc gatcattccg
    12601 atcactgccc cgccgatacc tccaccgata caagcagtaa taaatgggcg tcctagaggt
    12661 aatgttactc cgtaaatcaa tggttcgccg attcctagga tcccgactgg taaagctcct
    12721 ttgatcattt ctgttaattc tttatctttt ttgcagcgaa tccataatgc caatgctgca
    12781 cccacttgtc ctgcaccagc catcgcaaga attggaagca atagcgtacg accagtttca
    12841 tcaatcattt gcacatggat tggagtcaaa atttgatgca gtccgaacat aaccatcggc
    12901 aagaataatg tgcctagaac gaagccggca aatgctccac caacgccaag tacccagttg
    12961 atcccaccga ccatgccatc agaaatgaaa cctgctaaag gcatgatgaa gaaaatttca
    13021 atcagaccga tggcaatcaa tgaaagagtt ggtgtaacga tgatatctac cgcatcaggt
    13081 actactttat gcagtttttt ctcaacgatt gacaatagcc aaacagcgaa gatgacacct
    13141 aggatcccac cttgtccagc tgcaagagct tcaccagtaa ataagttttt cagtggtgct
    13201 tccggattca tccctgtcag catcacaacg gccccgataa ctccaccaag agttggtgtt
    13261 gcaccaaaaa cttgtgcagc attgatacct gtatagataa ctaggtagct aaacatcccg
    13321 tttttcaaga tgttcatcac atcgatatat tgttgccatg ttgctgcatc aagtgttccg
    13381 gctgtgacta agtttgctaa aactgcggca atccctgcca cgatcccagt accgacaaat
    13441 gcaggaatca ttggcacaaa gatattagaa atgtctttta ataccgattt gattttagat
    13501 ggtttttgtt tcgatttttg tgccgctttc atttcttgtg cccgttcgtt tacacggtct
    13561 tttccagatg ctgatgaatt tgctgtagct gtacttacag aagaaagttt ttctcctaat
    13621 ttcacgcctg ccaaatcaac catttgctgt gctactttgt tcactttccc aggtccgatg
    13681 atgacttgaa gctgttcatc ttctactaca ccaagcactc ctggaatcgc ttttaattca
    13741 gagacattta caagatcatc attgatgatc ttcatacgca cacgagtcat gcagtggaca
    13801 atgctttcta cattgcccat gccgcctgcc cctttataaa tttgttttgc cagttcttcc
    13861 aaagtcagtt cgttttttgc catggtcttt tccccctcat aaggtccctt ttacaaatcc
    13921 gtttgcttca gctaattttg cttgagcttc ctctttatca ctatttgtca aaatcatgac
    13981 gatagccagc ttaacatttt gatctgcttc ttcaaagtac ttttcagctg tttcgtaatc
    14041 agcttctgtc gcttgcatga tgattcgttt tgagcgttcg attagttttt cgtttgttgg
    14101 tttgacatcg accatcaagt tattgaatac tttacctata ccaatcatac tgatagtaga
    14161 aatcatattc aagataagtt tttgtgctgt tcctgacttc aatcgagtag agcctgtcaa
    14221 aaattctgga cctgcatcga cttcgattgg gaaatccgcg tgtttactga tttcggcttg
    14281 tttattgcaa gaaatcgttc ctgtgacagc accgatcgat tttgcgtaat ctaatccacc
    14341 gatcacatat ggtgtacgac cgctagctgc gataccaata actatatcat tttttgtcaa
    14401 attcagcttg attagatctt cttgccctag ctcataagaa tcttcggccc cttcgacagc
    14461 tacagtcatt gcttcttctc caccagcaat tagacctatg accatttccg gttctacacc
    14521 gaatgtcggt acgcattcag cagcatctaa cacacctagt cttccacttg ttccggctcc
    14581 catataaatc agacgtccac cttttttaaa ggactcaatc gtgttagcaa tcactggttc
    14641 gatacttgtc agttcttttt caaccgcagc ggccactttc tgatcttctt tgttcattag
    14701 ttgaacggct tgagaaatac tcatctcatc taatccaaaa gtttcttggt ttctgcgttc
    14761 cgttgttagg ttctctaaat tgattttgct catttttatc ttccttcttt tcttataaat
    14821 tgatagttca taccagcttt gatttggttg atcaatggta gctcttcttt gataacttta
    14881 gctactacat tcactttttc atccgctggc aaatcatatt tggttaattg gatctcaccc
    14941 atatagcgca aatacttttc gttatctaaa gtaatagacc ctttcatacg cgtagctgta
    15001 tttcttgctg ggataggcgg aatctctcga aaacgtgcat ctacgcttcg tatgacatct
    15061 cttgcatcgt cttgccgatt cgtatgcttc cctaatatat attcgtaaaa ttcttcatct
    15121 acaggttccg tatggagcaa gactgtctgt tctttttgga aagaagcaaa ttgctcctga
    15181 acgttttctg acagacctgc atctccgatg taaacaatat ccgtgttact tgctaataga
    15241 tctagagcgc ctgcaagagg atggatccct cgatgttctt ccaaagttgg caatccttga
    15301 tatagtgggc ctctcaactc tgtatctcct ggtacaaaac cttggacaag gagaccttga
    15361 attttgagcc attgattttt tttctgatac cattctttgt ccagccctgt ttcgggacgt
    15421 ggataataat tatgccaagc ttcaatctgt gagaaatcag cttctgcttc tttcaattca
    15481 tcgatatctt taggcgtgat cgtgctagca ttcaaactga ttttcaattg atgtgaccag
    15541 tcggcaatct gctgattgga aatatgataa tccattctta aacctgttac accaattgct
    15601 ttcaaaggcg ttagatcttc taatgaaaaa cccgctcgtt ccaatgcctc tcctgaaata
    15661 tcgaccatca attctagttt attctttttc gcttcgcttc ctagttcgat caatcgcttt
    15721 tgatatgccg aaacatcatc ttctggtata tgcatggaag tgaaaatacc gacaaagcca
    15781 ttggatgcca tttggcggat atactgtttc ttctcttctg acaaagaatc gttcataaat
    15841 attgaaaagc caaacatatt atccctcttt ttctgtatcc gtcttcattt ctatgactag
    15901 agtatatatc taaagaaaca aaatttcaat acttttatta aaacaattaa atttcatttc
    15961 taaaggttga gtttatatta tcaaaagaat tgtcataacc taaaaaaggc actgctaagc
    16021 aaaagcagtg ccttgaaata ttttatttaa ataacacaaa aacataatta ctcataagaa
    16081 accaattctg tattatctac catgaatgta aagaacccct cattaggcat cggatgaaaa
    16141 taagcattga tcactcttat caaggcatta tggcaaacta acagatagac attttcttcg
    16201 tcttcgatgc attctttcaa taaaggaacg atccgtgcat acacatctaa gactgactcc
    16261 ccatttggga atcgtacagc gaacgctaaa cgtgcttttt gaaagttctc atctttgctt
    16321 ggcagtccat cataatcccc aaaatccatt tctaccaatc gttcatcaac ggtcagcggc
    16381 aagctgagac gatcagcaac tgcttgtgct gtatctcttg ctcgttgaag aggggaatgg
    16441 atgattttcg tgattggaac aggcaaatct actacctttt ctgctagttt ctgtgcctgc
    16501 atctgtcctt tttcagccag cggcacatct gcccgtccgc aaactaatcc ttgtgcgttc
    16561 caagttgttt ctccgtgtct cgttacataa agcatgtgat tctctccttc gttggcaaag
    16621 ttccccttaa ccataccttg ttgttcttga gattacaagg gttagattct ctcaagagaa
    16681 ataatctcag tagatacttt atccaggaag gtttgatcat gttccactag taacatggca
    16741 ggtttcacgt tcaagatcag ttgttctaat tgttcttgat tgaagacatc caaataattc
    16801 aatggttcat cccatgtata tagttcagct ggctgtgata aagatttagc caattccact
    16861 tttttccgtt ggcccatact catctgctcg atcttgttat gaaaaacatc tctttccatc
    16921 ccaagctttc ggaggttgtt caaaaatgct tggtagtcta cttggttttt ctctgcaaat
    16981 tccgccaacg ttcctcgatt gtcttcataa ttttggcttg cataactaat gctcagatgt
    17041 tttggctggt atttttctcc tataaccttg ccgttgaatg cccccagaag ataatggata
    17101 atggatgact ttcctgcacc gttaggacct gaaatcgcca cccgctgatg aggctcgatt
    17161 gtaaaatgaa ttggctcgaa taacagattt tcatacccta attgaagatc ttctacgctt
    17221 aaaagtcgct tatggtgaga cgcttggcta ttcatcgtca aagaatcgat atattcgata
    17281 tcttttaata gtttttcttt ctcgctgatc tgggtctcca tccgattcac gattgctttg
    17341 gatcgtttca tcgtccgtgc agcatcagca cccactgctc ctttattcac tcgtctagat
    17401 tcagtatcga tgaatccgac ttgtttcttt gttttatctc cttctcggga acgagaccat
    17461 tcggcttttt cagctgctgt tttctttagc ctactgactt cttttttcaa tttttcattt
    17521 tgagccattt caaattcatc acgaagtttt ttctgttctt catagataga gaaattccct
    17581 tgataaagtt ccagttgact tttttcgatt gctaaaacat ggtccactac ttcatcgata
    17641 aatccccggt catggctgac cacgatgaag ccttgttttt tctttttcaa ataagccgct
    17701 acttgttttc taccagagat atccaaatga ttcgttggtt catcgattaa cgggaaatga
    17761 gtgtcatcca caaataaaag tgccagtagg acttttgtct tctctccccc cgatagtgtg
    17821 ctgaattctc tccataagat ttcaggatct gtttgcatca attggagctc tctttcgatt
    17881 tcccatatct caaaatccgt aatatcattt aacacgtaat aggttaaacg ttctttatct
    17941 tttgtctgtt gcgggaaata ggcaaattct tgctgatgga ttacttgccc ttgataaggt
    18001 agtttgtttt gtagaatatt cagtaaagtt gtctttcctc gaccgtttcg tccgataagt
    18061 cctagtttcc attgtgtgtc aaaatttaga tttgcttgtt caaataataa tgtgccttgg
    18121 ctgtcgtagc cgaatgtcag attttttatt tcgattttag acattttcca tcacctcgta
    18181 aaaaaagacc agtcctattt tcagaactgg ctaaagagga tacaagggtt ggatacacac
    18241 aaaaagaccc atacatcgaa aaaaccaagc caatcccgaa aatctgcaca ctgcttcctt
    18301 gtctccacaa ggtacagtct gaatgcagct ttcatcaatc gacttaattt ttcaatgcac
    18361 ggatccctca ctttgtccta tatttgaaat tacgatagca taaagaaaat gattttgtca
    18421 actacttcgg gaggatggtg aaaaatctgc taagtgtctg tcctaagatt tttgtttttt
    18481 ctaatgtttg cctgtgttcc attgcttctt ctaaacctat tggacccaaa tgaatactta
    18541 agacaattgg gagaaaatca gaaagtcctt ctagctcttg gtctctactt ccgcaaatag
    18601 cgattattgg ttttcgatat ttttttgcaa gcactgctac accgtatgga acttttccgt
    18661 ggatcgtttg ctgatcgatc cgcccttctc ctgtaatgat gacatctgct tgttcgatct
    18721 ttttttccaa tccagtgatt tggctgacta aatcgaaacc agaaaccatc ttcgctccca
    18781 acaaaaaaag ggctccacca ataccgcctg ctgctccact tcctggaata tcatctaaat
    18841 ccacctccca gaaatctttt atttgctgag caatctttcc tgcttgttta tctaagaaag
    18901 ctagcgtcgt atctattcct cctttttgtc ttccaaattg ccaagcagct ccttgttgac
    18961 ctgtatatgg attggtaaca tctgcagcga taatcaattt tactttagaa acaagaacgt
    19021 ttcttcgatc aaaatgaagt tttttagtag ataataaagg atttccttct gtgtaccctt
    19081 ctaaagaagc acccaaggat tggagtaatc ctagaccacc atcgctacac ccgcttcctc
    19141 ctaaagtgac aataatttgt tctacttctt gaagcagtgc atctttaata agttctccta
    19201 aggcataact ggaagcaagt cggatagttt gatccgttgg tttatcaagt agatctaacc
    19261 ccaatgcttg tgcagattcg atgactgcgg tgttttttcc ttgccaagtt gtcaataaat
    19321 agctgatttt tcgctgacgg aataagagat ccatcccatc aatggtacgc catgttcccc
    19381 tgagcgcgta atagattgct tctgcagtat tttctccgcc atctgcaatc ggcacattga
    19441 tttttcttcc tttacgatct tcccagccat ttagaactgc ctgatttagt tcaaatgaag
    19501 aagcacttcc tttaaatgaa tcaattgccg ccaaaatatc catctgtatc cctcactttc
    19561 ttcttaagta agacactttt tttcattttt ttcaaacaaa acaatgctat tttcttccat
    19621 ttttctatat actaaaaggg aactcattga ataaaggaga gaaaaaacat gaaaatcgca
    19681 atagctgggg ccggagcaat gggcagccga atcggattga tgctacatca aagcggaaat
    19741 gaggtcctct tgatcgatcg ttggcctgct cacattgaag ccattcgtac aaatgggttg
    19801 attgctgact ttaacggtaa agaagtggtc gcaaaactgc caatctattc accagaagaa
    19861 atcatcgaaa gcaacgaaca cgtggacttg atcgtagcat taacaaaagc caatcaatta
    19921 gatgatatgt tttgttcgat ccaatccatt attactgaca atacttatgt tttgtgttta
    19981 ctaaatggat taggtcatga agatgtactg gaaaaatatg tgccaaagaa aaatatctta
    20041 tttgggatca cgatgtggac agctggtcta gctggtcccg gaaaagtcac attgttaggt
    20101 gatggagaaa tcgaactaga gaacttggaa ccagaaggcg aagcatttac aaaaaaagtt
    20161 gtagaagtct ttcaagaagc aaatttaaat ccgatctata gccataacgt tcgttattcc
    20221 atttggcgaa aagcttgtgt aaatggaaca ttgaatggtt tatgcacgat tttggattgt
    20281 aatattgctg aactaggcgc gcaaaaagcg gcagagagca tggttcgaac aatcgtatct
    20341 gaatttgctt ctatcgcagc aaaagaagga atcatactag atcaagaaga agtgtaccaa
    20401 catattgctt ctacttatga tcctgacaac atcgggttgc attacccatc tatgtaccaa
    20461 gacctgatca aaaaccatcg tttgactgaa atcgactaca tcaatggtgc catttggcga
    20521 aaaggacaaa aatatgatat tgctacacca tattgtgcct ttttgaccca attagtccat
    20581 gcaaaagaag gaatccttgg cgcagaataa aaggctctct gatgagaatc agctgaatca
    20641 gcagctggtt ctcttttttt aagcccaata aaagatcaaa aagaaaacac aactctcatg
    20701 atgccataag aattgtgctt gtttgtttca gtacataatc tcttcaaaat gtaggttttt
    20761 tatttgtttt caacagagga gaggtcatat tcgtattgct cataaatagt ggaatcgtta
    20821 gtgataaatc gttttgccca attttctgca tcataaaatt ccaatagctc tgataggatt
    20881 ggcttaaatg atgtatgcag aaattccggt aattcatcta aatcacgttc tcgaagcaaa
    20941 aaaatatttt caggacgata aaaatgataa tgagcaatcg cttgattatc cgtcactagt
    21001 ttcttttgaa aatacatgga ttcaaatgtc cgcaaagtca ctccttgctg accctcccgc
    21061 aacagttcca gaatcccgcg cgattcccct gtttttttca ggtactcttc ataagtaaga
    21121 tatccaggtt gttcattccc tcgatgtgga agaatgaaat agttggtcgt aacatctctt
    21181 tttataaatt cctgcttata gctttctgct cgttcttttc tcccattatt cgttgcacca
    21241 aaaaatagat ccgtctttgg ttcgctagaa gaaaaattca tatgtttcga ataaaatgaa
    21301 ctattatgtt tcagcccaag ttcttttgct tccaaaaaat caaaatgata aatctcatcg
    21361 attgccggtt catcttgtgc ctgcttcagc atcgcctcgt gttctgcttt gaagtgattc
    21421 caaaaaaata acacaatttt tgcattggta aatgggcgca cgcgtcgagc catctccata
    21481 ttaaatccat aatctaaaaa aacgatcagc tgataatttg ccaactgttg tctagctgat
    21541 ttaatgaatt ccgactgtag taaatctttt ccggaccaaa catctaaaga gcggatggaa
    21601 ggcaaaaaat aaagtgattt attttttgca actagcagta cgtcattttt gttcatcttt
    21661 tccgcctcac tttctctgtc actttttcct atgatagcct gtttaaatag taaaaagcca
    21721 gtaaaacgct tcctatattt gtatgaaaat ttaacatttg tatgaaaata tgatgaaata
    21781 aatcattctt ctattaaaat tcgcctaaaa gttttctgaa tagttgtaat tgtctgaaaa
    21841 tttgttatca ttagtcattg ttaaatattg ctatttattc ttaatataaa ttttgattgt
    21901 gaatttaaaa gaaagaggtc atttatggaa gataaaaaat tgaaaaaaca acttagctcc
    21961 agacatatca ccatgttagc tttaggtgga gcaatcggtg caggtctatt taaaggaagt
    22021 ggcgaagcga ttgggatcgc cggcccttct gtattgattg cttttttgat tggcgggctg
    22081 attttatata tcgtgatgaa aggtctggga aaaatcgttt taagcggtgg cgacacgcat
    22141 cacggattat ctggtttgat acgcccttat ctaggtgctc attctgctga ttttactgat
    22201 tgggtctact ggtctatgtg gattatcaat atcatcgctg aagctgttgc agctgcttcc
    22261 tttttgcagt tgtggttccc gcacattcca gcctgggtat ttgtttttat gttggctgtt
    22321 ttaactacga tcatcaatct ttattcggta cggttattcg cagaaacaga atattggctg
    22381 gcttttgcta aaatcagtgt cattatctta ctaatcattt ttgctactta tcttgtcggt
    22441 cagcaaatgt tgggcacagg cgttttccct acccttcagc aattgactga ccatggtggg
    22501 tttactcctc atggtatgaa gggaatcatc agttctttgc ttgtagttat ctattcttac
    22561 ggcggttctg aactgattgc tatcacggta agcgaagcag atgatcctaa acgtgcgatt
    22621 cctaaagcca tcaaaggtgt catgggaaga atcatttcct tttacatcat tcctttgttt
    22681 ttgcttttga ttctttttcc ttggaatact ttagcaggca cgaatgtcag tccttttgtg
    22741 atggtatttg aaaaaatgaa tatcccattt gcagcggata tcgtcaattt tgttattgtc
    22801 cttgctttgt tctcatctat caattcgggt gtgtatgcat cttcaagaat tttgttcttc
    22861 cgtttgaagg atcgaaaagg ttcctctaga aaactagctg ttttaaacaa gcatcaagta
    22921 ccgcaacgtg ctgttttatt ttgtaccagt gttctttatc ttggtgtagc tctttcttat
    22981 tttgtcggtg acaaattatt tggctatctg gcaggttccc tttcgtatac agtattattg
    23041 atctggatca ttatcagtgc ggcatccttt gtactggcac taagaaaagg aacattatgg
    23101 gataaaggaa tcagcttttt tgcattagct gtcttaggat tgattttcct tggtatcctg
    23161 ttcacgaact ccattggggt aactgtattg actggcctgc tttacctgtt catttatttc
    23221 agttatcaaa aaaagaatga tgcgttcgta ttgacgaatg aatgaaatcg atagaaaatt
    23281 ttattttatt tatgtggaat agatggaact attgaagaaa ggagttgtga caaaagtctt
    23341 gttgcaactc ctttttccga ataaacagtc tcatgacctc ttggtaaacg gtgttcaaaa
    23401 accctctgtg caaaataatt gattgttctc catgctcatg acatgataga agaaaggaat
    23461 gaaaaaaagg agtttgtttt aaatgaaaaa gtattggaag tttttgttga tgatcggtgt
    23521 ttcaacggta gttatgtttg gtatgatgta cttgaatgtc tatgcgctcg atcatatctt
    23581 cttcagtcgt acacgagtat tcatggcgtt gatgatgggt gcagtcatgg cagtcatcat
    23641 gctgttgttc atgtggaaaa tgtatgaaaa caaaaagata aatgttatga tcttagccgc
    23701 tagtcttctt gtttttgccg gttccttgtt tatggtacga agccaaacta ctgtcaacga
    23761 cacagcttgg atgaaggcca tgattcctca tcattctatc gctatcctga caagtaaacg
    23821 agctgattta aaagatcctg aagtaaaaaa attagcggaa gaaatcatcc aggcacaaga
    23881 agaagagatc gacaaaatga aaaaaatgat caaagaaatg gaatgaccat tatccgtcca
    23941 aataaaaaaa gaggatgttc cagaagtgat cagcttcaag aaataagaag aagctacttc
    24001 tggaacaccg tgaataaggg gttgtgaaaa agctgccctg catcaagtaa taagaacagc
    24061 caaacaaaaa tagcttctcc tatttttcgt ttggttaggc ttattaccgc agatgcaagc
    24121 ttttgaacac cgtttattcg taaaagggat tgtgacaaaa aaagtcttgt cacaatccct
    24181 ttttatgttt ttattgttct aattgcgctg tcttgcttac tgcttcttgc ggtttcacaa
    24241 atttttttga gattccccaa cctgtgaagg cactgaccat cgaaaacaca ggagaaagca
    24301 aactgaaaaa tacgaatggc aagtaagtga gtgtaggaat accaaatgta cttgctacga
    24361 aacttccggc aattccccaa ggcactaagt agttgattac tgttccacca tcttctagcg
    24421 ttctacctaa tacagttgga tcaaatcctg ctttttcata agtttcttta aatgcattac
    24481 caggcagaat aacagatagg aattgttcac caataaaaat atttactccg atacttgtca
    24541 tcaatgttgt aaaaatcaat tttggtgtgt tcgtcatctt tcttgatact cgttccatca
    24601 cggttgagat caagccaaat tcgatcaaca atccacctaa tgacaaagtt agaataatca
    24661 atgacacagt aggcatcata ctttcgattc ctccgcgact aagcagtgaa tcgatttgtt
    24721 ggtttccagt atttgaaaca aaccctgatt cgatgacccc agccaacttc gttaaggaag
    24781 tttgtgggtt ttgaataaaa atcattccta ctgctacagc gatattcaac aaaatcgtca
    24841 aaattgccgg cacctttttc catgcacaca gtaacattaa aaataaagga atcagtgacc
    24901 agattgaaat agtaaagttt gcttctagaa catcagtcac ttcacgaata gatgaaagac
    24961 ttgcggcttt acttgtgtgc cctaaaatca tgaataaaaa gaaagaaaca acaaatgccg
    25021 gaacagttga ccacatcata tgcttgatgt gtttgaacaa atcggcatca acaatagctg
    25081 ctgctagatt tgttgattcg gataatggag acatcttatc tccaaaaacg gcacctgaaa
    25141 caatagctcc aacaaccagc gctggattta ggcctagtgt tgtcccaata ccgaaaaatg
    25201 caatcccaat cgttgacata acagtaaagg cactccctac agcgctacct acgattgcac
    25261 acacaacaaa tacagaaggg acaaaccact ggacactgat caatttgaac ccaatgacca
    25321 ttagagttgg aatgatccct gcttgtatcc atacagcaat caatgaacct actaaaataa
    25381 aaataaagat tgggatgatt cctggtttga tgccattgat gattccttcg tgcagccaat
    25441 ctgtcgggta tctttttatc actgcataca acatgaccat tccgatcgct gctaagatcg
    25501 tgatattagg tgagaccttt aatccgacaa cgccaatcgc aatgcctaaa acaataacca
    25561 ttaatacaag tgttgcttct aaaaaacttg gtgttccttt ttttcccatg ataatctctc
    25621 cttttttagt tgttcttatg ttctaaaaaa gttaagatat cggattactc cgccgcaatt
    25681 catccgctat tcctccttta taaaaataaa aagacctgtt ttaaactaag gacgaatgac
    25741 tccgcggtac caccttaatt aaaaacagat ctgtttttca ctttcaaact tttattcaaa
    25801 tgtatggact ttccatgtaa ttcgtcaatt aggcttgatc ggttcacagc gaccaccgac
    25861 tttctgaaca aaacacctaa ccgctactgc gtgaaaagtt gacttgtatg aagtttacct
    25921 tccataagat catttgtcaa tgaaaaagaa aatatttttt catttttctg aaaattattt
    25981 ttataacttt cacacacaag tttatttttt actagaaagt agcaccctct tgtttttttc
    26041 ttgctactat ttcttgatgt tcttgcttga ttctttctaa tagctttggc tctttcaaca
    26101 gatcaagagc tgtattggcg agtagttctg ctgcaatcgc aatagaagca aggcctttgt
    26161 cacttttagc agcagctttg aattcttctg tgtgtccggc aatatatgtc tcagagattg
    26221 ctaccgtagg ctggattgtt ggtatgactt ggctgacatt tcctacatca gaagaaccga
    26281 gacttgttct ttgttccgtt tctatttctt catctggaac acctgcttct tttgcatgct
    26341 ggaagaataa gtcatcaaaa gaaggagtaa cgatgacatc atcaactgca ttttggaaca
    26401 atccaaactc aaaagtcgtg cccgtactta tcgcagcacc tcgtacgata ttttccactt
    26461 tttcatatac tttatctaat gtttgccgat ttcctgcacg taaatagaaa cgtccagcag
    26521 cgtaatctgg aatgacgttg gcagctactc ctccgtctgt aatgatccca tggatattga
    26581 catcttttgg caattgcaag cgtagagcgt tgattccatt aaacacttgg atcaatgctt
    26641 ccaaagcatt tactcctttt tcaggtgctg ctgctgcatg ggaagcgaca ccgtaaaatt
    26701 tgatgtcgac tggatcattc gctaaagatt ctgtcgtttt cccataacga aaagctggat
    26761 ggacgcataa cgctacatcg acatcctcaa aaaaaccttc tcgaacaaag ctgcctttag
    26821 ctgatccgtt ctcgccccct tcttcccctg gggtgccata tacacggatt tctccaccag
    26881 tttcatcaat aaattgctcc actatgctgg cggctaatac ggagtaagta ccaaacaaat
    26941 tatgcccgca tgcatgacca atacctggta aagcatcgaa ttctgccaaa aaggcaattg
    27001 tgggtccggg tttattggaa atataacgtg catcaaaggc tgttcggtgt ccagctactt
    27061 ctttttctac ccaaaaccct tctttttcta attgtttaat caacgctgct gaggaataaa
    27121 actcatagtt acttacttca ggatgttcgt ggatatctag agcaagtgct tgatattctg
    27181 gtaaacgata ttggattaga tccttcaatt ggtttgttga gattgttgtt gtcataaaaa
    27241 attcctccta tgctagtcat ttttcttatt ttctcccgaa tgtttcccat gcaggcacgc
    27301 ttgatccttt tgatgttttc tcgattactt tgactgtgtc ttctgtttga taagcgtcta
    27361 ctattttttg atacgtttta tttttttcat cttcttttct tgcaacgatg atattcacat
    27421 aaggacgtgc atggtcatcc actggttcta agaagatggc atcagaagca ggattaaatc
    27481 cagcatctac agctacaccg ctattgatca ctgaaatgtc tacatctgac aaagcacgtg
    27541 ctgtttggga agcatctaat tcagaaatgt ctagattttt tctattctcg gtaatatcag
    27601 aaacagtggg cgcttgtcct tttgccttat ccactttgat caatccagca gtttgcaata
    27661 acagaagagc tctgccgcca tttgtaacat cattagggat tgctactttt gctccgtctt
    27721 tgatatcagc tacatccttc aaagtgttag aataaattcc cagcggtgca ttgacagtat
    27781 ttccgatcga tactaaatca gttccgtgtt ctttattgta attgtctaaa aagaattgat
    27841 gttggaaaga attcaaatca atcgatccat ctgctaaagc cgcatttggt tgattgtaat
    27901 ctgtaaattt cacgtattcc aaattaatgt tctccttttt caaacggtct ttcacgttgt
    27961 cccatacatc tgtatcttct ccaataattc ctagttttac ggtagtttct tttttgtcag
    28021 ttgtatctgc ttttccttgg ctacaccctg ccaaccaaat aattgctaca aatgtaatga
    28081 ctacaaaacg aataattttt ttcatttttt ctcctccact ttcaatgtgt aattttttta
    28141 atcagttgat tactgataaa ttgacttaaa aaaactaaga ttagaatcaa taatgtagcc
    28201 acaatcgtta catctgtttg gaatcgatta taccctctcg atatagcaag attccctaat
    28261 ccgcctgcac ctactgctcc agccatggta gtcagtccga tcacgttgat gatagtcaac
    28321 gccgagaccc gaatgatacc aggcaaacct tctaacaaat acacacgtaa aataataccg
    28381 attggactgg ttcccatcgc ttctgccgct tcgatcaccc caggatcaac ttctagcagt
    28441 gcgttctcga tttgacgagc aaaaaacgga acaactccaa aaatcaatgg cactaaagct
    28501 gctttcgcac caatcgtcgt tccaactaag aaacgagtag tcaatgctaa aagagaaagc
    28561 aagataatga aagggatgga acgaatgata ttgatcagct tatcaagtat ttcaaatagc
    28621 agacggttag ctagtaatcc attagggcgt gtcactacta acgtcacacc taagatgatt
    28681 ccgatcatcc cgccaatgaa tgctgtccaa aaagacatat atagtgtttg cttcgtcgct
    28741 tcgacaaatt catccggaat caaataaaca ttgggcaaat atgttttaaa gaaatcagtc
    28801 attttatctt cctccttcga tcactttgat acgactatct aattcgtttt tttgtaaaat
    28861 atttattttt acaccagatt tgatcaaata atccaatgct ttttgccgct gtttggtttc
    28921 tccagctaaa gtaacgatca aactccctaa cggcgtttct tgtaataact ctacattgcc
    28981 atataaaata ttcgctgtta cttgatattt gctgtacaga tgagcgatta gaggttcgtt
    29041 cgtctgattt ccaatataac ttaattccac cagccattta ttggcgatct gatcggcaaa
    29101 agcagaatgg gcaatgatcg tttctaatgc ttggtcaaga tgagtagctg ttcgaataaa
    29161 atctttggtc aattcttctt caggattgct gaagatctgg atgctactac ctttttcaat
    29221 gattcttcca tcttccataa ccgctacctt gttgcagatt tctttgacaa cttgcatctc
    29281 atgagtgatc aggacgattg ttaaacctaa ctggcgattc aattttttta acaatgcaag
    29341 gatctgaagg gtcgttttcg gatcaagtgc actggttgct tcatcacata ataatacctt
    29401 aggttcattc gccaaagctc gtgcgattgc tactcgttgt ttttgtcccc ccgacagttg
    29461 tttaggataa gcagatgctt tttcttccaa accgacaagt tccagtagtt cattcacttt
    29521 ttgacgacgt tcctgtttcg attttccaga atactttaaa gaaaaatcaa cgttgtcaaa
    29581 aatagttcgg ctttccatta gattgaaatg ctgaaagatc ataccgatgg cctttctttc
    29641 ttttcgcaat tctttgggag agagctgact caaattcgtc tgattgacaa tgacttctcc
    29701 tgctgttggt ttctgcagca aattcatcac acgaactaac gtacttttcc ctgcacctga
    29761 gtaaccgacg attccataaa catcgccttt ttcaatcgtt aaatctacag aatctactgc
    29821 ctgtatctct ttttcttttt gtttgaaaca tacagaaaca tctcgcaatt caatcattaa
    29881 aattcctcct tatctaaaaa aagcgtcctc aagaaaatga aaatgtcatt ttcttgagga
    29941 cgcttttttg cgtgttacca cctcatgttc aagctgtgtt cacacacaac tcctcttcaa
    30001 gtacgatcat actctagcaa gatatcggtc gcagccgtca tcgccttaca tctatgctcg
    30061 ggatgaattg ctcgatggcc attttccaat agtcgttcct tgcttcttct cagctaccga
    30121 agctctctgt caaaggttct tctatcgtac ttaccatttc aatgcaaata atattcaaaa
    30181 aaaaatcctt ttactaacat aaactatgtc agtaaaagga cgacgtatcg cggtaccacc
    30241 ttttttcgga agtttccttc cctcaagccc aacatctcaa aaagagagat tggcgttcgt
    30301 tttaacggtc gaacagttcc gaatttgcct acttatcgac aaattattct ccaaggccat
    30361 tttcagcttt tcttacttga ctcttctcac cagccagagc ctctctgcaa agtttccaaa
    30421 cttactttcc ttttcaacga aatcgatatt ttgttgttgg gattaatcta catgaggaaa
    30481 actaaaaagt caagcacgaa attcaaatta ttttttctat atttattttt ctgttttttt
    30541 atctaacatt tcaataacag ttcgaagatc ttttccttca gcaagaagtt tcaatttttc
    30601 cttttcttcg acggtataat ttcggacaaa actggaatca ggtatcaaaa caacgcctaa
    30661 tcctgctcgt gaagcagctg ttgctcctac taaagaatct tccactgcaa aggctgaact
    30721 agcttctaat cctgttcgtt ccaaagctgt cagataagga atcggtgaag gcttgttctc
    30781 cgacacttcg tctccgaatg taaacgtgtc aaagtaatca gctaatttaa agtgatccaa
    30841 gatatctgtt gctcttttcg taacagtggt cgtagcaatg cctagtttca tatgacgttc
    30901 ttttaagtct gccaatattt cttttgcata tggttttaag tggatggctc cgcttgtcag
    30961 ctgttgataa aaatattctt cacgcttcgc tcggacttcc tgtacttttt cagggctacc
    31021 tgctgctttc actaaaatat caaaactttg tttccagttt tttccgcccc aagcgtcaac
    31081 gatttctttt gggatatgga tatcaaattg ctgaaatccc caaagccagc catcacgata
    31141 cgttttttct gtgtcaacta acaaaccatc taaatcaaat attgcacctt tcatctatac
    31201 attaatcctt tccaaaacaa tacacatagt ttagcacgac tggtccaaaa ataacagaag
    31261 caaagaacca gccttctcgt ttataagagt tcttggaatc gatggatata gattttcttc
    31321 acagctgtca caagcgccag ataagcgatg actgtagcaa ataaccataa ccagtaattg
    31381 ccaggaagtg gcatcaagcc taattcagca ccaaaacttg taaaaggaag gacagaaccg
    31441 acaataattc ctaatgtagt gataacaaac atggcaaatg ttacgttgct ttggataaat
    31501 ggtactttcg gtgtacgcag tgcatggagc actaaggttt gtgtccatag tgattcgaca
    31561 aaccatcctg catggaataa tgcgatgaaa atcacttgct gtgaactatc caatgtatgg
    31621 aaacttccgc caactacagc aggacaaata acaaaataca tcaacaagta agtagtaata
    31681 tcaaatatcg aacttgttgg gccaaagtaa accatgaatt tcccaatact agatgcattc
    31741 catttttttg gctcgtccaa atattcttta tccatccgat cccatggcaa ggaaatgcag
    31801 gaaacatcat agattagatt caaaaacaga agttgtaaag gcagcattgg taaaaatggc
    31861 aggaacatac ttgcaatcag cacggaaaac atattgccaa aattagaact tgctgtagcc
    31921 ttgatatatt tcatgatatt cccaaaagtt tctcgtccag aaagaaggcc tctttccaaa
    31981 atcgtcaaat ctttttctaa aaggatcacg tctgcagatt ctttcgcaat atccacagct
    32041 gtatctacag aaataccgat atcagccact ttcattgcag gagcgtcatt gataccatct
    32101 cctaaaaatc cgacagtatg accattttta cgtaaagctg tcgtcaaacg tgctttttgc
    32161 tgaggattca attttacgaa tacttcatgg tcttcagcta cttgtgctaa ttcatgatca
    32221 ctcatttccg agattttctc accggtaacc aattcattga tctctagacc tacttgacgg
    32281 cacactgaac gtgtaactaa ttcgttgtcc ccagtcagaa cttttacagc tacaccatgt
    32341 tctttcagag ctttcaacgc ttgtttcgtt gtttcttttg gtggatcaag gaaagtaaga
    32401 taaccaatca aaaccatgtc tgactcatct ttgactgaaa attctccaac gacgcttgga
    32461 ttggtctttt gtgcgacacc aatcactcgt aagccatctt cattaagtga ctgtactttt
    32521 gcaagtacgg cttcttttcg ttcttttgtt aatggtgtaa cagtaccgcc aagatcaata
    32581 aatttagaaa tgttcagcat ttcttcaatc gcgccttttg tgatcatttg tgttttacca
    32641 gctggatcag caaccacaac actcatacga cgacgttcaa aatcaaaagg aatttcatcc
    32701 actttttgat aattgatctt atctgtatct aaagtttctg ttgcttcatc aatgatagcc
    32761 acatctaaca aatttttcag ccctgtttga tagtagctat ttagatacgc atggcgcaaa
    32821 acacgatcat cttcatttcc ttcacaatcc atatgatatt caagaatgat tttatcttgt
    32881 gtcaatgtcc ccgttttatc cgtgcataac acatcgattg caccaaagtt ttggatggca
    32941 ttcaaatttt tgatcactgt tccttttttg gccatcacac ttgctccttt gaccaaattc
    33001 gtcgtaacga tcattggaag catttcaggt gttagaccaa ctgctacaga tagtccaaaa
    33061 agaaaagctt ctagccaatc cccttttgta agcccattga tgacgataac tgctggagcc
    33121 atcaatgaca taaatttgat cagtagcatg gatgttttat ggatgcctaa ttcaaagctt
    33181 gattgaattg gtttttcaga tagcgtttct gctacatgac caaatagtgt ttcatttcca
    33241 acagaaacaa tgattccttc cgcacttcca cttatgacat tacttcccat aaagacaaga
    33301 ttttcgtaac ttgtttcgct ttgctgatcg tcttcacata ctttcgcatg cttttctact
    33361 ggatagcttt cccctgtcaa tgctgcttgg gaaatgaata aatcctttgc ggacaataaa
    33421 cgcatatccg ctggtatcat atcccctgct gaaagccgaa caagatctcc acagacgatt
    33481 tcttccatag gaatctctgt gtactttcca ttacgtttta cagctgccgt tactttcaca
    33541 agtgatttca gtttttcagc cgcttgattg gaacgtacgg actgaatcaa cgtcattgtc
    33601 ccgctgacga tgaccatagt gaagataatg gctacaccga aaagatcttt atctccagga
    33661 gctgctaata catattccgt gatgaatgaa ataattccta atgcgatcaa cactaatgta
    33721 aatggcgtga tgtatgcttt caatatttct acgatgaatg gtgttttttt gccatatgaa
    33781 atcgcatttt caccgtaatt ttctcttgaa cgttcgattt gttcttctgt caatccattt
    33841 gctgatgcgt ggaatagttc aaataattct tgtttcgttt ttccagcaaa agctgcatag
    33901 attttttgtg tatctttctt tttttccatc tcaatctctc ctttgtgtcc aaaagacagc
    33961 tgttctcgct gcttttggtc tttagctatt catcggatcg atagagaaaa aactgaaagg
    34021 ggctgagaac agatagataa tagccttggc ctttcctcta gatccttgtt tttcgaatga
    34081 ctgtcatcca tttgttctca tctcctttac taagtaattt taattcatga cttccaatca
    34141 tttttcgaat agttattttc ccaattagac cacctccttt ttatttttca ccgatgggga
    34201 tttgcggcaa caaaaaaacc tctcgccaaa tactcagcga aaggtttgaa aaagcatatt
    34261 aaaaaaagct tctcagatct catcgttgag ttttgacact gtacaacgta aaaagcagat
    34321 acctgctttt agctacctta tgaaaagcct tatctcgaca attcctgttc tacccattgg
    34381 cgtctctcga cgtttttggg cagtagccta tgtttgtata ggagcctcac ctaacaaatc
    34441 ttattcggtt ttccttcgtt aatataacaa ctaaaaaaga ggatgtcaaa tcaattttcc
    34501 atgtttttca tacttttttt aaaatacaca cgttatattc ctgtctcacg cggttttatt
    34561 tgtctcattt tccacctccc gctataatag aaatatagta ggaaacgagg tgctgttatg
    34621 gaaagaacac ttgttattat caagccagac ggcgtgagac gccatttagt cggaagcatc
    34681 attcaacgtt ttgaagcaaa gggactggcc attgctgaaa tgaagtttga aactatgact
    34741 cctgaattag caaaagaaca ttatcagcac ttgactgagc gcagtttttt tgatgaactg
    34801 atcgattaca tgacttccgg tcctgtcgtt tatcttgtgc tggtcggcga ggaagtgatc
    34861 gatatcgtcc gtaagatggt tggggcaaca aaagctgtcg atgctgttcc aggtacgatc
    34921 cgaggagact acgcgctgcc ggggactgaa aacatcattc acgcttctga ttcccgtgat
    34981 gctgcggtaa aagagatcgc ccgctttttc ccgccattcg atataaacaa accgtctgaa
    35041 aaagcggcga agtgatacaa attctaaact gctggtctag ttgctgggtt cagcaatggc
    35101 cagcagtttt ttctctaagg acctccgttg attctttcct aacatatatt cgagcactgt
    35161 gaagaattct tggtagtctt tcgtcttttt ttcccctaaa gcagcagaaa tcaatctttg
    35221 ataataatct gccatcaatg tttcatagat cactgtactt ctttctttat gtgctaagct
    35281 ccgtttcata tcttcattca cactacgtgc ctttttcaac cgaccatttt ctatataaaa
    35341 cgaagtcagg ttcattaaaa aagtaaagag atactgctca tgattgttca actgtgctaa
    35401 tcgtcgcatt ctttttttga ttttcaaata attgttctca atgaaccgat cactgaatat
    35461 ccaaggaaaa tcagctagaa tagatagttc aaattgacca tagtctggta tctgcatcaa
    35521 gtattcttca atgattcggc attcataacg taaaaattca aattctgtct cagatacttc
    35581 tgttttttcg accatgtgaa gactcaaaac caaataatac agatcttctg ttttcttaaa
    35641 atgcctacgg ttattgctga tctctttata aggatcaaag ctgtcttctt gtacccgatc
    35701 tagcattcgt ctttttttct ttaactttat tggttcatcc agctggtttc gcatccattc
    35761 atattctgca agtgtcatgt tcattcgctc taaaaatgat ctcaatgtta caaatgacat
    35821 ttttttcact gaatttgtct caatcccgac tagagaagtc ttagaacaga ttccttccgc
    35881 taattgggac tgtgtcaact tcttgttgac tcgaagtttc ttgatcaatt caccatcata
    35941 cataatagtt ctccttttta atttaaattt ttccacattc aataaataga tacgttaaaa
    36001 aggaaaaata cacgaaaaaa ataaaaaaat gtttttttca taaaaaatac caaccttcaa
    36061 gcattagaat gttgtctaac tactgaaggt tggtttgatt gtttattgat tatctttttg
    36121 ctgttcaacg tctgttcttg ttactggata taagttggtt gttgttttat tgccattttt
    36181 tgaaaagaca cttgtcgaat gttcgccttt ttgcttttcg atggctatgt tacgttctgc
    36241 ttcattttta tagtcatatt ttttcggatc gatcgtttca aatccgtttg gcacataaaa
    36301 acgcaagaga ttttcttgat tcagcttatc tgaaagactt aaagcagatt tgactttttc
    36361 ctgatctttg gaaatttcct cgtcgattcc tgctgctttc gtatcgatga tttctcctgt
    36421 ttggttattg taagcttttc ctcctaagat ggtgtatttg ggtgtcacga agttcccatt
    36481 tcgaaaagcc actacttgat catgctgagg agataataaa tccgtaccaa aatggagata
    36541 gtctttatca tcgattccca agagatgaag taatgtcggc aaaacatcga tttctccacc
    36601 gtattcgtga ttgactgacc ctttagtata accaggtata tgaatcatta atggcacacg
    36661 ctgcatttgt gcgttgtcaa attcattcca tgtatctggg tcttttccaa gagcacttgc
    36721 taagtcttta ttatctgtat ttgagatgcc aaaatgatcc ccataaatca caaagatcga
    36781 attttggtaa atagcggatt ttttcaggta cgtaaaaaat tgttccaatg actgatccaa
    36841 ataatgtgcc gttcgaacat agttatctac tgtgctattt ccagtgttca aagatggaaa
    36901 atcgaaattc ttatcatccg tataataagg cgtgtgattg gttacggaaa ggaatttcgt
    36961 gtagaacggc tgttgtagat gttcaagata ttgggcagat tcactgaata aatctttatc
    37021 taatattcca taacctagcg tttcatctga ttcatcaaaa taagatcgat caaagaaatt
    37081 gtcataacct aagtttttat atacatgatc tctattccaa aaactagcta cattcccatg
    37141 gaaaacagcg cttgtatagc cttgcttttg tccaaggatc gctggtgcgg cttgaaagac
    37201 attatctgac ccaagttctg tgaataatga gccttgaggt aaaccaaatg tgccagtttc
    37261 caacatattt tcagcatcac ttgtctttcc ctgtcctact tcatgaaaaa aattatcaaa
    37321 gctgatcgtt gcttgattct ggaaaatact atttaaaaac ggtgtgactt cttgtccgtc
    37381 taccttcata ttaatcaaaa actgctggaa actttctaaa tggagaacga tcacattttt
    37441 ccctttagcg atcccaaatg tttcgggatt tggctctgca taatgtttct ttgtataatc
    37501 taaaacttca tcaatcccat tactgcttgc atgcgcgcga acactgctag tcattcctgt
    37561 tttgattcca tcataaatag tatacgcatc gattcctaga tatttgacaa tatatgaacg
    37621 gtcaaatgtt cgctgcagca attgtggacg gttggcttcg ctcagcgcta gatttcctga
    37681 aaaaataagc cctgaaagac aggtcacagc gatagccatc ggtttgctga caggttgact
    37741 tttgataggt attttcttga tcgtcaacca aaccagtatc ccaatgaacg tagcaatatc
    37801 cagccagtag aggacatcat ggggtttcat caaagaaaag gagcttcctg ataacccttg
    37861 cgacactttc gaaaatccca atacagattt gactgtaatg aaatctgtga attcccgata
    37921 aaaaataatg ttcaagtaca acaaaagcgt gtttaaaata tcaatgatca aaagaatggc
    37981 taatgctggc tttggctttt taatatacaa agaaaggcca aaaaacaata aggtagttgc
    38041 aatcgggttg atccacaaga taaagtactg gatcgtacct tccacaccta acgaaaaatc
    38101 tgcatagtaa gcaataatcg tcttcatcca gaaaaagaaa acagctgtca aaacgattgc
    38161 taaacgattt tggcacaatt ttttaagttg tgtcacgtat atcacttctc tctattcaca
    38221 tttttcctta ttttgctcct gaaaaatgaa aattccctaa aaaagttgtt atcttaagat
    38281 ttttttattc tttctaaaga ttattccgtg cacttttcac agcataaaac cgctgtgata
    38341 taagcgattg aaacagtaag gtgataaaag tcttgtcgca gctcctgttt agttgatgca
    38401 ggacagcttt ttcacaactt cttctttaaa cggtgttctc ctgccaactc ctcggccaca
    38461 agtcacaata tttataaaac atgagaagct gttttttgaa attgttcctt gtggctcaga
    38521 gttaaacggc aagctcaaga cctcttgata cacggtgttc aatcagctga ccttcggtat
    38581 tagctcaaaa aacggcaaaa tatgaggaac tattttgccg tttgtttctc taatactcag
    38641 gtcaaaacgc tgatttcaca acctctgttt ttcattgtcc ataggattga tattgtcctt
    38701 gtgatgactc attcgtaata attgaggctt gattttcttc acttcccgtt atcgtttgtc
    38761 cactgccaga atctgaagga cttgttcctg tcgactcgtt tttttgagaa gagacagttg
    38821 ttttcttgac ttgttcattt gtctttttcc attccgctaa acgatcggcg accacttttt
    38881 tgtctacttt ttcagaataa gcggtgatca cttttccatt tttcaaacgg gctactttgt
    38941 cgccatcatg agtcaaaagc aaaacggtca aatgcttgtc tttaaattga tattgtctga
    39001 gagaaatcgc actaagtacg tcatcgatat taataaattg attttcttct tttccttttg
    39061 gcaaatagat gtccaattcg cctttttcgt aattggcagt tattttatac tccgcccacc
    39121 aataagttga gaattctttt ttgaaattat ctactgattc tttgcttgct acgatttttt
    39181 ctgtttcttt ctgagcaaga tctgctgtca tttttcctga aaatgctgcg gataaaataa
    39241 gcagtaagaa aaaaccgaat aaccaaaaga gaagaaacgg tctttttttc ctcatgcttt
    39301 cctccactcc tatttaattt tgactattct attatataca aaaaatgaaa tagaaagaca
    39361 aaaaagttga aaaagatcgt aaataattga acttcttttt cacaaaatgg taagaatgga
    39421 gaatttcacg catttgctct caactattct ttcttaagcc tcaaatccgt ttttatctga
    39481 tacgtctttg aaccagtgac ccgatttttt gattgttctt tttccatctt gtgctaagtc
    39541 tactgaaata aagccatatc gattcttata tgcattggtc catgaccagt tatccataca
    39601 tgtccacata tgatagccta aacaattggc accttcttga attgcttgat ggacatattt
    39661 cagatgagat tggacaaatt cgatccgata atcatcgtgg atcatgccat cttctttgat
    39721 aaatcgtgct tcgttttcta cacccatacc gttttcagaa ataaagcagt cgatatttcc
    39781 ataatgatct cgtacattga tcaaaatatc atagattcct tgttcataga tctcccatcc
    39841 gcgataagga ttcattttac gaccaggcat ttcataattg tcgaaataat cctcaggcat
    39901 tggaccgttt ttagtatcga ttggtgtttc ttttgctttt acccggcgtg gctggtaata
    39961 attgatacct aaaagatcta ctgtattttc tttgatgacc gtcaaatcct ctggatggat
    40021 cacaggcatg agatcaagtt cttttactat ctcaatcaat tcacttggaa actcgccttt
    40081 tacagctgga tcaaggaatg aacgattgaa gaacgcatct gctatttgcg ctgctttaac
    40141 atcttcaggg tttgattcgt ctcttggata gcttggtgtc agattcaaga tgataccaat
    40201 aacaccacct tgctccattt catggtaaga tttgatggct aacgctgagg ccaacgcttc
    40261 atgatagcca acttggatcg cttttttcat atctgactct tctggataat gccatcgata
    40321 taaataacct gcttcgactg gaacgattgg ttcattatga gtaaaccatt tttttacttt
    40381 cgaaccgaac aattcaaaac aacttttggc atatttttca taggcttcaa ccgtttctcg
    40441 gttcaaccat ccgccttttt cttgcagata catcggcata tcgaaatgat acagattcac
    40501 aaagggttcg ataccgtttt caatcaactc atcaaaataa cgatgataga aacgaacggc
    40561 ttcttcgttg attgttccag attcatcagg tatcaagcgg ctccattgga tagatgttcg
    40621 aaatgaatta tgcccagtct gtttcatcaa ctgtacatcc tcttgatact tcgtataaac
    40681 ttgtgaagtt ttttcaggtc ctacttggtc aaagaacttt tgcggttctt ttttgtacca
    40741 ataatcaaaa atgttctctc cttttccatc acctgaaatc cttccttctg tttgtgggcc
    40801 acttgctgca gaaccccacc aaaaatttgc tggaaattga tattttttca tcaaagcacc
    40861 tctttttctt ttttagttcg ttttagttga ttccatgtat gatattttcc atcacaatta
    40921 ctttttcatt ttcttcctct tcttttttga ttcgtttcaa cagctgttct gcggcttgtt
    40981 ccccgatttt atctgttggt ggtgtaatcg tgattttcgg aaggatgctc aaatcgtttt
    41041 tatccaaata atcataatga ctaaacgcaa tatccttccc gattctgata ccttcttgat
    41101 tgaaacattc gatagcaccg atcgacatat tataattgct gacaaaaatc gctgttactc
    41161 ctttttctaa taattctttt gccccataat agccactttt tctagaatag tctcctgtaa
    41221 agacctctaa ttggatcgat ggatcatttt gtaccgcttc ttttgctcct gctaaacgtt
    41281 ctcttgctac gtagtctgtt tgagtggcag caataaatcc gattttttta tgtccttgtt
    41341 caccatgatg agcgatcact tttgctacac tttctcgatc attcactaat attgtatcaa
    41401 tacctgctgg tccttctggg caattcaatg cgataactgg aatactcatt tttgtgagca
    41461 tttcaaatcc agaccactct tcttcggata agaagacaat cagcccatcg atcacatgct
    41521 tcatcaggta ttcaattttt tgttcaattt tttctggctg atcggcaaac ccgcttaata
    41581 ataagctata cccattttct tcagctactc tttcgatccc tgagacaact tccgacccaa
    41641 aacggctgga aatcccgttt atcaaaagtc caatagagaa gcttcgatta ttcttcaacc
    41701 ctttagcaat gatgttttct ttatagtcca acgctgaaat cgcttctgct atttttttca
    41761 tgttcttttc cttcagttgc tgaccattca agtaacggga aactgttccc actgaaacac
    41821 cagccatctt agccacgtca cggatcgatg ccatacattc tcactcctgc cagttacatt
    41881 tgatttctct ttcttgttgt tcgattatga tgaccgcttt ctttgcatag tgttgcttgt
    41941 catcaatatc catataacta aagtcttcag tagagcaact tcctctcact attaattata
    42001 cttaaacaag tatttgaacc ggttcatttt taatatagca tttttttaaa agattgcaac
    42061 acttttttaa aacgctttcc taaaatggcg aattttttgc ctttttaaaa ttttattcta
    42121 aaatttactc tatttgtggg tgttttgtgc gtttttctct tccatccgtt tgaagtttta
    42181 ctttccaatg gtataatttc tttatcctat caaatggggg aagtattttg aagaaattaa
    42241 tcgtactatt tattttgtct gcgggacttt tgacattgac tggctgtaat ttgtttggcg
    42301 gctctgacca atcctcggat gaaacaaccg attcttctgt cttaaaagcg gaaaaagcag
    42361 atatcactaa cagtgtatat acgctaaaag tacgtaaaga tatggattta tccgcgggac
    42421 agttgacatt tacagataaa aaaatggaat ggacacgcac gtatcagaca caagaaactg
    42481 attcttctga atcatctgaa gaaaaaacag tgctgacaga catcaagatt actaccaaag
    42541 atgacgaata tattatttca ggaaaagaaa ataaaaaaga agcaaccatc acatttacca
    42601 aaatcggtaa ttaccgtttg aaggatgagg atggcaacat ctacagtcta tagtgccgtc
    42661 tgttggatct tcttttgttt ctccccttct tttctgctat agtaaagaag caagatgatt
    42721 gtaaaggaga cgaaatggat gatcgatagt cctgattatt gtacatgtaa taacaacaaa
    42781 aatatccata cagaatttaa tgaccaagga agcttgagca tatgcgacaa ctgtcacaaa
    42841 ctagtcaaag attcatttaa aacatttgaa tcttatcctg ttcaaaatta tgtaaaaagt
    42901 agaagaagat aaacaaatcc aagcaaaact cactatggct gatttttatg aacttcaaac
    42961 tcagcttctt cctttgatca agcttcatca gtaaaacaaa cagtggatca tttcagttta
    43021 caaatcaaag agtaaagatt tatttatttc aaatatttga atataaaata accaaacgat
    43081 agaaaggctt attctacatc acgtagtaat ttttctttcc cgtcgtttgg ttttttattt
    43141 ttagcctaat tcttgacctt ttgcatgctg gttatccgta aaatattttc cagcaggctt
    43201 tccttccaat tcagctagtt tttcttggat ctgatggatc accttttttg catcttctgg
    43261 attttctaca aaatcgaatt tatccccatc cacttgtatt ttaggacata catcaaaatc
    43321 ttcataccat tgattatagc gggtgttcaa cgtttcataa taggtatata acgtctcatc
    43381 gctttctagc tgttcatagt cacgcccacg ttttttgata cgttctagca tcgtgtccaa
    43441 agaaactttg atatggacca tcaaatcagg ccgttttttt ggagcaacat catctaactc
    43501 gtttagcatc gtatctaata agctatcgta ctgctgtact tcgatatccg ttacccgacc
    43561 taaatcagcg tttagatgga acaacaggct atcttcatag atggatcggt ctagcacatt
    43621 gtcatcgttc actaaagcat ttttcattgc taaaaatcgc ttgttcaaaa agaagatttg
    43681 caataaaaaa gcgtactgct caggatttga ataaaagagc ggcaatactt cgttatcttc
    43741 gacattttca taaaatggtt tagaatcaat ctcttttgca agcatatccg tcaaactgct
    43801 cttacctgca ccaatcgttc ctgaaatcaa aatcactgac atacaaccct tcctcttcta
    43861 taagtactcg cctacgtaag tttcaacagg caatgtttca aaatcatatt cacgtacagc
    43921 ttggtctgat tttaaatacg tatggagact ttgtgtaatc atcaagttcg taggtaccgt
    43981 ctcttcttgt acaatgatca tcggtttttt caacatagtt gccacaccta attcgtaagc
    44041 cgttcctgga tcgattgttt gatgctcaaa gtcaaggata gcaacaacaa attctgcatt
    44101 tgtcagttct tccatatctt tttcgtatac ttcctgcgcc catccagcgc tgaatagttc
    44161 ataattgctt tcttggtgat gacgtggaga gtagaaactt gtgactgttt tgttttcctc
    44221 caacgctttt tcgatacgac ttactcgatc gatttgctcc tctgaaaaaa atggtcctgc
    44281 taaatatatt tgactcatta ttttgcctcc ttcaataata actgattttt aatagatact
    44341 gctcgtaatt cattgaccag ttccaatgga ttgttggaaa agattacttg atccaaccat
    44401 tttttatcca taaaatcctc ttttgcaaaa gtttctaata attgttgcaa gccgctgtaa
    44461 taaccgccaa tattcaatat tccgattggc ttgtcgggcg tcagaccgat tgctatccaa
    44521 gaaagaagtt gtgagaattc ctccaatgta cctagacctc cagggaaaac gaggacagca
    44581 tctccctttt caaataataa tacctttctt tcatcgatcg tttctgtagg aataaatgta
    44641 gtaacatctt ttccaggcaa ttcagtttca aaaagcccat tcggatagat acctgtgact
    44701 tttccgttat tttccagtac tgttttacta atcactccca taatcccgga gtatgaacca
    44761 ccgtaaacca gttcgatttc ttcttgtgcc atgtattttc ctaacgtttg cgcaataaat
    44821 ttgtaacttt ctttattacc aaaacgggaa ccgcaaaaaa cagtaagttt cataaaaaaa
    44881 cactccctaa ctcaaaagtc tatcttcatt ctacacgtgt ttttttaaaa taaaagacta
    44941 gattttgtag ttttttagtg gtatatagga tagacaccac tatatatagt atttagaaaa
    45001 aaacattttt cagctatttt atagataaaa caaaaataaa taacgtgttt tcatcgatgt
    45061 gaaatgactt acttatagaa gatactggga tttcgtccta tatgccaata acgtgtatta
    45121 ttttaaacaa caaatacttg tttcttttat taacgaaaaa atcattttgt tctcgtgtta
    45181 tgtttcactg ataaatgatg tttctctaaa taaaaaagcc gacgaactaa acgatcaaaa
    45241 tttgatcatt tttgttcatc agcttctcct aaaaatcttt ttgttaacga taaatagctg
    45301 gatttgtaaa aatatcactt gaatcgtcac tgctggaaga aaattcagtg ataaccgcac
    45361 ctgttgcgcc tgcctggaac tagtgtttga tattgggctc gaacgtgtac tgatctctag
    45421 catgaagaat aatttctttt tttactgtat aataactttc tttccttttt ggaatagtac
    45481 aggaaagttt ttttgtttcc tttccttcga cataaggtat accagaccct ttcgacaacg
    45541 aaaggttctc atttttcctt catcgtcatt tcaaggaggg tgccgatgct ctggacagtt
    45601 tcgatcgctc ctaaaccaaa atctgtatat tcgattcttt ctaactctga ttctttcata
    45661 ccattcctgc ctcaaggtac atctattgta cttttttctt gtaatccact ctgcctctcc
    45721 taactaattg tcaaatcatc ccaagatatg tcttcttcct ctttttcttc ttggatgatt
    45781 tctgcattcg gatctactgg ttttttcaat aataaaatgg ttattcctgt gacaaaagaa
    45841 ccagctaaca atgcaccaat gaatgcccat ggtctggtca tcgtagcgac tgcaaacatt
    45901 cccgatgccg gaatacggct atctgcgccc caaaacatgc ttaatccgcc acctactgtc
    45961 ccaccgactc ccgttgctat gacattgcgt gccaagtcgt tcaatacgat agggaaacat
    46021 ccctctgtga tctgacagat ccccatagga aaagcggtct tcaatgtatc gatttcttga
    46081 cgattgagta tatttttacg aatgattttc cctaagaaat aagcgatcgt caagccgaat
    46141 ggggttacca tcgaagctaa aatcaataca gtgattggtt catagattcc ttctgaaaat
    46201 cgtgccacac ccccttatcc agaataaatg gtaatccaga aacagccgtg tatctgcggt
    46261 aataagccta accaaacgaa aaatatgaga agctattttt gtttggctgt tcttattact
    46321 tgatgcaggg cagctttttc acaacctctt tttttattta tgtttcataa tcaatatggt
    46381 aaggatgcag ctccgtatgg tagaccgcct ccgaatattc aatcatttcc ccaatttgcg
    46441 tagacgattt ccgtatccgt ttgatgccga tctgtgcgtc tgttttcaga attccttgtt
    46501 cttcttctgt taaaaatact gccgagaaat catcagaaaa tgagtcaata gtatatcctt
    46561 ttttcgtcag caaacgatac aaagattctt tgccaaattc ttctctgctg aattgcatca
    46621 tttcttgtgg aagataatga acaaaataaa tataaggctg attgttcaaa taatataagc
    46681 gcttaaaaca aacagcttgc tcaccgaaaa aggaaaacaa aggatcttcc ttctttatat
    46741 ggaccaattg caaatccagc gtttctttcc ggacttcata tcgggagttc tccaagattt
    46801 gcgtaaagct tgccgctttg gataatcgat tgtaaggacg attgcttaga accgtcgtcc
    46861 cacgaccact tttctttgcg acatattcat ctgatgccag cagttcgatt gcctttcgga
    46921 cagtgatttt gctgacttga aacagttctt ctaattcact ttctgtcggc aacatcgaac
    46981 cgactggata ttttcctgag aaaatatctt ctttaatttt atctgcgact tccaagtata
    47041 gtacacgtgt ccttttcata acgtcaccct ttgctttact attactaaaa gaatagcaca
    47101 taaaaaataa aaaaagaaca caaatcacat gtgagaagtg tgttcttttt cattcagctg
    47161 ctttaattac aagtttacgc catttgaggc aattacttct ttataccaat caaaagattt
    47221 tttctttgat cgattcagtg tcccatttcc ttcatcgtct agatccacat agataaagcc
    47281 gtaacgttta ctcatttctc ctgttgatgc actgacaaga tcgatacatc cccaaggcgt
    47341 atagcccatc aaatctacac cgtctgctac tgcattagcc atcgcttcga tatgacgacg
    47401 taaataatcg atccgataat catcaataat cgtgccatcc tcttccatat gatcaatggc
    47461 tccaagaccg ttttcaacaa tgaataatgg tttctggtaa cgattgtata attcattcaa
    47521 tgcgattctc agcccttctg gatcgatctg ccagccccat tcacttgcct caagaaacgg
    47581 attttttact cctcccagca agttcccttc tgaagttgct gcttgtggat cagtctcatt
    47641 gattgccgta gacatataat aactaaatcc gatgtagtcc actggatatt cttttagcaa
    47701 ctggaagtct ttttccgttt gctctaattt ttccggatcg actccatatt ttttatgggt
    47761 acgcgctgtg tatgcagggt attctccacg tacttggaca tccgtgcaga aaaaattgaa
    47821 ttcttggttt tggatcattg ttgctgcctg attgactgga ttggcatcga tgctgtaagt
    47881 tgttgcatag ataatcatgc agccgatttg gatatccgaa cgcaattcgt ggccgatttt
    47941 tacggctttg ctacttgcaa cgaattgatt atgccatgct tggaaaatat tttggtactc
    48001 tcctgctcca ttgcttttta ctaatccttg acttaaagct ggaaagtgaa aggccgaatt
    48061 gatttcattg aaagtcatcc aatatttgac tttactgctg tatctctcta atactgtctg
    48121 agcaaatcgt tcatagaagt cgatcagttt tcgatttttc cagccaccgt attcttttgc
    48181 caaatgaaga ggcatttcgt aatgagaaat cgtgatcaca ggttcaatat catattttaa
    48241 gcactcatca atcagctgat cataaaattc taatcccgct tcgttaggag taccttcgtc
    48301 tccatttgga aaaattcgtg tccaggcaat cgaaaaacga taacatttga atcccatttc
    48361 cgcaaacaag gcaagatctt ctttgaaacg atcgtaatga tcgattcctc gatgattcgg
    48421 gtaaatatat ttttcttgat caatcgtcca gtcaaattct tcactgccga taatcgcaaa
    48481 gcgctgctta cctccaggca tagcatctgc aacggatagt ccttttccgt ctcgatcata
    48541 agccccttct aattgatttg gcagcagttg ctccacccca taaaaatttt tctgaaaaac
    48601 gtgattgcat cctgatttcc tccttatttt acaattgcca gaacatcttc gtttgcaata
    48661 atctcttttt ggtctaattc aagtatatcg gcaaatgcat cagtattcgt aatgacaact
    48721 ggagtgatta cgctatagcc agctgctcta attgcttcga tgtcaaaacg aatcaataaa
    48781 tctcctgctt tgacgagatc cccttgtttg actaagatct caaagccatt cccatttaat
    48841 tctactgtat ccatcccgat atgaatcaaa atctccgctc cgtcagtcgt tgtgatccct
    48901 acagcatgtc cagttggaaa aatagtcgtg atctctccgt ctgcaggtgc aactagttct
    48961 cctacttctg gatcaatagc gatacctttt cccatcacgc cagaagaaaa aacttggtct
    49021 ggtacttcac tcaatggcag tactttaccc gttaaaggac tttttaaggt atgccgtgct
    49081 gaagtaatcg gttctcctgc attcgcatgt ttgttttcta attgattgtc ttgtgtttgt
    49141 tcgtcaaatc ctaaaatcaa tgtacctacg aatgcaagaa caaaagcaat tcctgtagct
    49201 attactgcta ctgtcacatt tgactctaca ccatccaccg tattaatgaa agtcggaatc
    49261 gtcaataagc tgaccaaact gctggagaaa gcttttactc cggaaaatcc gataatagct
    49321 ccaccaatac ctccagaaat acaagcggca atgaatggtt tcttcaaagg taatgtcaca
    49381 ccatacacag ttggttcagt gattccaaat aacgaagtca ctgtagaaga aatccctaat
    49441 gctcgaagtt tcgtatcttt tgttcgcaat gctacagcta aagcagcccc accttgtgcc
    49501 aagatggctg gaagaagcat tggcatcaat acatcaaacc catattgttc gatattcaaa
    49561 aacatgatcg gtacgaatcc ccaatgcatg ccgaacatca cgaatacttg ccataaactt
    49621 cccatgatta gacctgctac gattggacta aatccataaa tcgagttgaa gagaccgcct
    49681 aaagcattac cggcaaccgt cccgattggt cctaaagcaa gaaatgttaa tggaaccatc
    49741 actactaaaa cgacaagcgg aactaaaatc atttgcagaa attgcggaat cacttttttt
    49801 tacgaatggc tctaatttac tttgaaccca tacggctaga atgattggta tgacagaaga
    49861 agtataacca gatggtgaaa gaatcactgg gatcccaaag aaactgatag cttctcccgc
    49921 accagcaact gctgtgatag ctggatacac aagtgccata gcaattgcta ctgctaaaaa
    49981 ctggttggct ttgaactttt tagctgctgt aaaagcaagc atgacaggta agaaggtaaa
    50041 gacaccatct gctgcagcaa acaatatttg ataagtaccg ctatcagctg tcagccagcc
    50101 catcaccgtt gccaatgata agaatccttt caataccccg gcggctgcca tcgcccctag
    50161 aaaaggtgta aatatactag agataatatc gatcagacga ttcaaaatat ttttggactc
    50221 ttcttttcca tcctccgaaa ctgcaagacc ttcctcatcc acgatcgatt gataaacatc
    50281 tgctacatta ctgccaatca ctacttgata ctgaccgcca ctttgtacga cttggatcac
    50341 gtccgggtct tcttttaact tttgcgtatc tgctaaagat tcatctttta atctgaatcg
    50401 caaccgcgta gcacaatgta ctaaactttt gacattcttt tgtcctccta ccgcttccca
    50461 tacacgacga ccaactgctt gattatccat tgttttttcc ttctttcttt tttatttaaa
    50521 aaataaaaac ccagattgaa aaaaacagtc acaaacattc gtgaacctat tttttcaatc
    50581 caggttttgc ctgccataca gtaacaatcc ttatgattgg atgctttttt tctcacttac
    50641 tactctttga atatgaatcg ttaaataaat ctgctctgcg atccccattt cctgtttttg
    50701 cgtttgtcga agatactcat tgatccgttc gacacaatga aacgcttttg gatactttcc
    50761 ttgaactaat gcgtagagaa attcatcttg ctcgtcagat ccttcccctt tgagataacg
    50821 ctgggcaaaa aactgcagat gagtaatgat acgctgataa ttcaaagatt cttcatcgaa
    50881 cacgatgccg aagaatttac tgatgatact cagtatatct cttaccattg tggtagcggt
    50941 catcgtcact tgcatgtctt cgtttccttg ttggctattc acaaaatgaa aggcaataaa
    51001 accggcttca tcctcagaaa gttccacacc cgtcttttgt ttcacgaaca aaagagcctc
    51061 tttcgctgct tgatattctt tcggataaaa tttttttgtt tcaaataata atggattagg
    51121 cagttggata ttttcttttg ctcgtgtgat cgcataatga agatgatcgg tcaatgtcag
    51181 ataaatatta ggcgaaaatt caacttttag tttatcttca gccagttcga ctacttgttt
    51241 gacccattcg atctcctctg ccggaatatc agccatcagc tgctggaatt ggtttttagc
    51301 aaaagaatct cttaaaacaa attctttttg gaccgcttct ggcgaaatct cgtccccaat
    51361 ctttttttga aaagctagtc cttttcccat acaaacgact tcttccccga atccattttt
    51421 cgaaatgacg acattgttat tcaaaatttt atcaattttc attttgcttc gccctctcaa
    51481 gaaaaataaa aaaacctaga attcgcctac tgtttcttag ctgaattctg gttttgcctg
    51541 ccgtacagta acaatccatt tcttattcaa aatcatcata ccatcgaatt tttatttatg
    51601 caagcctttt catataaaaa ataaaaaaac tggaacacaa gtctatctag aaaacaacca
    51661 aatcagagat gcacctcttt gcgtttctct ttttttcagc aaattggttt ttccttatcg
    51721 attcatatcc tttggctgtt tttaatctgt aacgacttat gtcccagtat cctaaaatgt
    51781 ttttgtctct agattgaaag cagatctcat atcatctgtc gcatctttta tcgatgtaac
    51841 actttccagt tctccttgta caactagtcg cgtgacggcg tccatgtcgc cacaagtaat
    51901 tagtgtgaca atttcttttc cctcgacttc attcagtaat tgggtatctg taggagcaac
    51961 tttttcttta aaaaatgttt tgtatgtata cacattttct aaatctgtca aatagatctt
    52021 ggcacccatc tctaaatttt ctagcggtgt aaacagcaat tcagggttcg ttgcacgatg
    52081 gcttgctaag gcataatttc cttttcccat ttcttgatct ggagataatg ttcctgctcc
    52141 gtaaagtagt gacgtattat ccaagccttt gaaaaccggt aaattgattg aaactgaagg
    52201 gactgcgata ctagcaatca ctggtagatc tgttcctctc atttgcgacc tcatgacccc
    52261 ttctgtcgtc attggttcta ccgcatcaaa gtcaaaactg acatctttat cgttattctt
    52321 tttcagatct tcttttgtta cattcgctat agcatattta tctcctgtct ctctgacaaa
    52381 ataatccttg atctgttcat tgaaaatcaa agctagtcct actaataaca agaggaacaa
    52441 gaggatattg actagccatc tttttgcttt tccttttttt ttcattttct ctccctccag
    52501 actcatttta ctgtttttct tttgctcttt ccaacagccg aatgacacat ttctacaact
    52561 ctgtgtattt ttttcgtaca cctgcgcttt tttctacagg atatttcaaa ttatttttga
    52621 tcaatttttc ttcaatgatc tcatctagat ccaggtgaag gttgtctgcc atcatgtatg
    52681 aatagatcaa tacatctgcc agttcttctt tgattcgttc taattgtgtt tcttttactt
    52741 cttccggcgt tttccattga aaaagttcta acaattcaga tgcttccaaa gaaatagaga
    52801 tagccaaatc tttttcgtta tgaaattgtc gccaattacg ttcatctcta aactggttga
    52861 ctttttccat actattcatt tgcttgcctt cttccaatca cttcttactt gattaatcat
    52921 accatttttt tacataaaaa atagatgatg cttttaaaaa aactcctgtt ttcttttatt
    52981 taaaataaat gtcatagaaa atcaataatt taggtagcca ccatgtgtat gcagtagcgt
    53041 gtcttcttcc cttgaggctt tttgtttttc gatacgttct tcttcccaaa cagacaacgc
    53101 tactagaatc tctcttaatg attttccttc ttcggtgagc gagtactcta ctttaggcgg
    53161 gacttggtta taggcttttc gatggatact ttcatcttgt tctaactctc ttaactgctg
    53221 ggtcagcatt ttttttgtga tcgtagggat ttgcttgctt ctccacgcct aaaataagcg
    53281 atattgctct tccctttatc tggtgtaagc aaagcagtta gcattttgac gatcgtgggt
    53341 tccgcttttc acttcttatc tacttagtat catgaagtat actttcgtac taatactaag
    53401 tagcggaagt gtcaactact ttgtttaact acatagcaaa agaaacagaa gggtgacaac
    53461 ggtcatcacg cttctgtttc ttttgaatat gctgtgttgt tgtctctatc tccgtgtaga
    53521 ctttcctcaa acttatcctt tgacagtaag tcagtaggct gatttgctct ttctagatgc
    53581 cagatacatt tctacaaaaa aatagtgatt ctgttttgaa aattcgattt ttagttctgc
    53641 attttcgtaa acatccaaca tttttttcgc actgtataga cctaacccgc catttttttt
    53701 agaggttttt cctcttttga ccatctccga tagcgtcaaa ttcgttggat ttgccttgtt
    53761 cgctatacta aaacgtgatc cctctttttc ttccagcaga ttgatcgtaa tcggactctg
    53821 atcggctaca cgatgatcga atgcgttaga aataaaaata gataaacagc gaataaaaac
    53881 aaccagatca atcgggattg ttttcacttc gacaggaata actacttgga tcgggatttt
    53941 ctccgattct gctttttcta gaaattttaa aaagacaccc ctgacagctg gggatacaat
    54001 atttgttagc tgttgtattt gcggtttttc aaaaatagct gcagaatgat cttctaatat
    54061 ttctaaaaat tccaacgttt cttttttatt ttcctgaaga gtaattttta atgaaaacag
    54121 tagactttta taatcatgtt tgaattcctc tagatgatgg taatattctt catttatttg
    54181 atacagttga agcgattcct gatgttgtct ttcttttact tggaaactga tcaacataat
    54241 ggaaaaaaac aaagaaaaaa aactgatgac tatcgacaaa agagatagaa gcagataatt
    54301 agatgagcgg aagtgaacac ttcccaatac caagtaaatc acgccccagc ttaataaaat
    54361 acaaatacct ccaaaatagt gttcagttgg ataagtaaaa agcaagttga gaaatctcgt
    54421 ctgtttgtct atacttttta ctaatagata gaaaataaat gcgataagta gtgcaaaaaa
    54481 acttgctgtt ccaagatgtc tctttcctaa ataatccatc agatcaaaaa ccagaaaaaa
    54541 gctgagtcca gtgatagcaa aaaaaagatt actgatcaaa cagctgataa acaggttttt
    54601 cgtagtaaaa taaaaaagaa acatcaataa taagccaact aggtaaggaa agctcacttt
    54661 agggatagga agtaaaagtg tcaccaccat caaagctata caaccaaagc tgttttttac
    54721 tagcagttgt ttcgaaaaga ataaatagat acctaaatct aaaatcaaag taaaggtcaa
    54781 ataaagtgtc actgttgcga ccatcttatt cctccattgt tttgtttcaa aatgtacaca
    54841 tattttttta ataggagcct gcatatgaaa aagtatttta tcatagaaga taaccagttt
    54901 cacagcgaat ggatcatcag agaattggtc aatcatcata tcgagaatat cgtgcagctc
    54961 acttctatct ctcaaatcaa tcagttgatc cagttgggca ctattgataa tcacgatgtt
    55021 ttctttatcg atatcgactt gaagcaatca ctcacaggta ttgatgtcgc cgaacaaata
    55081 cgtaaaaaaa atgcacatag taatattgtt tttttcaccg cttatacgaa ttttgcagta
    55141 gagatcatca atcggaaaat ccttccgatt ggatatatca gaaaagacag gaatttatct
    55201 gaacaaattc gtcaagtgct agaacagatc aattggaaag aacagcagat cgtaaatgtc
    55261 gataaaatct ttattgatca aaaaggtgga agtctcgtcc tgtatcctcg ggaaatttta
    55321 tatattgaaa gtatcaaagg tttgaaaaac caagttatgg tcaaaacaac tacagaagat
    55381 aaattagtga atacttcttt aaaacaattg aagacagagt tagaaaagta tgcttacttt
    55441 ttacttttaa aatcttactg tatcaactta tcgcaattgc agaaaattga ttctgctcat
    55501 tatgtgttag aatttttcaa cggtgactcc ttactcgttg gtcgaaagat ctttgaaaag
    55561 acaaaggaac gtttccatga cttccaaaaa actgcttcga gttgatgaat aagagctgag
    55621 acgtaagcat agcagatttc agggagtggg ccttgaatcg gctccactcc ctgaaatcgt
    55681 tgatatgatt ttacgcttcc tcttctgtag gagcatctgt taacgaccat gtgaatgttg
    55741 aaacgtagtt gtctacagca taattggata caggaacaaa taattccact gattgtctcc
    55801 cttgttccac attctctcct aatgaataaa tccatgtgcc aatcccttca tttgctcctg
    55861 cagttactag atctactgcc tgatctgctg ggatttcgat tccttcagcg ccagttccag
    55921 aaacggtaga tggcattcca ctgctattag ttgcgctatt tcgaatcacg gcgtttttga
    55981 atttcacctt tgaaccagtt agtttattcg tatcagatgt tgtaccaata aattctgttc
    56041 gtttgactga taatttccaa ccggcataat ttccgctttt atccgttact tgtacgaaat
    56101 tctgtacttg tgtttgtgct ccagtactgt ccgttccgct ttgtaatgca gcatatactg
    56161 tttttgctgt acctaacttg attgttccaa aatcaagatc tggagcttgg tcaatcgtca
    56221 gtaatccgga tgttccctga tttggttcgt caggtgtaaa aggagtatca ggatcatttg
    56281 gatcaacagg aggaactgga acaacgtctt caggatttgc agcatctggt ttggtcacag
    56341 aaatcgttcc ttctgtagtg gctgagctct tattctcagc aaaaacactt tgtgtacata
    56401 ataatagact tccagctaga acggtactta atgcaattgt ttttttcatt tctttttcct
    56461 tctttctttt aaaataaata atccagcaaa taagccaata agaatgactc caacaagtat
    56521 cagccatcgc cagtcaaatg tttctggctg attttttaaa tcaatatcct tttcattcaa
    56581 ttggtccgct gcatcatcag ttatttcaaa atcggtatgg agattccagc gtttttcttt
    56641 ccaagcaccc ttcacaaccg cttgataatg tcccggagct aatttttttc cttctaatgg
    56701 gacaagtaaa tcaaaatttg tattgggtgc tacatctatt ttttcttttt ttattgaaag
    56761 gtaaggctct tttgtttctt ttttgtagat ttcaaccgat gtagtcaagc cgaacatata
    56821 agaagcattt ggattttgaa gattcgcctt aatcacattt cttccatcgc tttgatccgc
    56881 ataagctttt tttaatttca aatctgggga agactctttt tcgctatttc aaatcaagat
    56941 tgctttcact tgagaaaact gattgacgac accaactgta cttttgttag aaacgttctc
    57001 ttttttttct tgaaacgtga tccctcctgc gaccacacca gccagctctt tttctggcgc
    57061 tttcagtgaa agtgtctcag tgaccgcact ttgaggagga acagttattt ctcccactgt
    57121 ttttgctaag tttttcatat cataacttaa tgtttcatca aatttacttt ttgattctcc
    57181 atattcgatc acaccgtttg aattcgtcgt agcggagtgg atcaatgtct caactgttac
    57241 tgatttatct gttcggttaa agaccgtgta ggggatttcc tgtgttttcc caggctccat
    57301 ccttacattt atatatgttt tgttcttatc aatctgatta gccggtaatt caaaatctac
    57361 cgcaaaattg aattcggagg catggacagg tgtctgccaa aggatgaatc caaggagaag
    57421 gatcataagt aaagagcagt tgtttcgatg acttttattc catattcgat tcatcaatca
    57481 tcctccttga tctttattct gtcggcgcat ctgctaatgt ccatgttatc tctgctgagt
    57541 aattaccagc tatctgattt tctttggtta agacaagttt aaacgcccga ccgttattta
    57601 aatattctga ataatctgct tgcacattcg ttgaattttg tcctctgaca atttccagtt
    57661 cttcttcatt cactaattga tactcctctc ctttcttgaa atataggaca tcctgcatag
    57721 aaaatcctgc atcatttgtg aaaggctgag ataattttat cgttaagatc cacggatttt
    57781 tcgtttctcg ctgatcataa atccataatt tttcctgtat atccatttgg ccaaatgctt
    57841 cttgtgtcaa accagttgct ttgatctgac caaaatcgag tttggaaggg gcaagaaatg
    57901 agagaccacc ttctactacg atcttcgtag caggtgcaaa aggcggggca tcatgataaa
    57961 caactggcgt atcacttgga ttgtgattcc caatttcatc gttggtactt ggcttgttct
    58021 gcacaccctt agcagtagct tctcctgctt ggtcgtttaa tacaatttct aatacatctc
    58081 ctgcaaaaag ttgattttct gggatagaaa gaacaaattc ccctgtatca tcaatagttg
    58141 tttctgacaa aacagcttga ttttttttca atgaaaccaa ggctcctgct tcacctgtac
    58201 ctgtgatcgt gcgagaagct gcattgatca atgtggtact taaattagca ggttcaggag
    58261 gaatcacatc gactgtcgtt ttggcagagt ccagttctgt cacttcttgg ccacctctta
    58321 cttttttagc agcaacaact tgcacttgat cctccgtttt taatctctca tcattgggta
    58381 cttgaacttc gaacaagccg ccttgttcgc cttctcccca tgggttatat cctgcccctt
    58441 cattttcatc tgtttgtcct tgcgtgagag cagtaatttc tacagatgat ttcgtcgtat
    58501 ctgcgtaagt aatacgtaaa gtcacttcta cttcgcctgt ccaagcatct cttggctttg
    58561 cctcgacacc ttcgggaaca acgacatgcc catagatttt tttatctgca ttcgttggca
    58621 ctcttaagga ttcaatcatc gggagctgat tattggcact gattcgatta taatttttca
    58681 ttccggcacc tgtctgagca aattcatttg ttaaacctgc actagggctt gatacgaaat
    58741 tgcctaagtc ggtcccattg atcgataagt ctgtcatatc agaaaaataa tccgggtctt
    58801 tttcaaagtt atcgaatgtt gcgcctgttt ttcgccataa agcgatttct gaatgggcga
    58861 tctttaaaga agaatctcca tttccttgga atacccagcc gcctatgcca ttggtctcgc
    58921 ttccaatccg tttgttttgg aaatcaaaat aggtaggaga ttctaagtcc acattcaaca
    58981 catccccact gatgatgccg gtcttatctt cccctgtttt cccgaccatg actaaataag
    59041 ttttttcacc tgccgtaaaa tttaaatcaa tatctccagt tgtatctaca gttgctccgg
    59101 aatctgcgcg tatatcgata tttgattttt ctccagtgac tgtaaaatca gctgaacctg
    59161 gactttctag aaaaccagaa gcgtcataaa attggatcgc ttgatttcct tgattgagtc
    59221 tgttcacgta agatttgcca tcacctgtat ttcttaccct caatgagcct ccattggtta
    59281 ctgtcagctt ttgcgtacca ttctcaaaac gaactgcgct ggaacgccca ctctgcttat
    59341 cgatgtcgat aactgatccg gctccttcta cgatcaaaga aaggcctttt cctacaaaac
    59401 gcatcccatt gttcccgggt tgatcgtcat ctccagccat tttgaccgag atttgtccac
    59461 cacttgatac atggatttga ctagaatctc cttgcaagcg aaatccgccc gtagttgctg
    59521 tattgatggt gattttccca ccattcgata cagtgacttt cgatcctgaa cctctcattt
    59581 ggatgattcc gcgattgttg tcattggtaa tattgatctt tgtatttacc gaaaattcgc
    59641 ttcccgaacc actgacttca aacatgacat taccaggtag cgtatcgact gcctctcctt
    59701 catcgctaac gccatctgcc cgatcataat caagagagac ctttgaaccg cttaagatat
    59761 ggattcctgg cgctgttttt ccactaccag tctcatctcc tgaatctaga aaaccgtaga
    59821 atttccctag atacggtcca taaagttgac taccattgat cacattcaat tgatagcttc
    59881 tacaaaaata ggctttaccc ggagcggcat tcagtccttc cttcactggt tggacatcca
    59941 acacaccgga aacaccatct aatgtgacag ttgcacgagg agcgtaaatc agtcctaatt
    60001 tggacccatc atacaaatca agtgtcccgg taaattttat ttctcccgta aaatgatatc
    60061 tgcttcccca aaaatcggtc atataagcaa tgataatggc atttccatcg atatttggtg
    60121 tcaatccacc tggatgtgca gctgttcc
//
LOCUS       DAYNVV010000009        59345 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.009, whole genome shotgun sequence.
ACCESSION   DAYNVV010000009 DAYNVV010000000
VERSION     DAYNVV010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59345
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.009"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(159..1469)
                     /locus_tag="ACGXWR_000715"
     CDS             complement(159..1469)
                     /locus_tag="ACGXWR_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004650 - polygalacturonase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28 protein"
                     /protein_id="HFK0802322.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1481..2899)
                     /locus_tag="ACGXWR_000716"
     CDS             complement(1481..2899)
                     /locus_tag="ACGXWR_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFK0802323.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3139..4707)
                     /locus_tag="ACGXWR_000717"
     CDS             complement(3139..4707)
                     /locus_tag="ACGXWR_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HFK0802324.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4711..5121)
                     /locus_tag="ACGXWR_000718"
     CDS             complement(4711..5121)
                     /locus_tag="ACGXWR_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HFK0802325.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5118..6041)
                     /locus_tag="ACGXWR_000719"
     CDS             complement(5118..6041)
                     /locus_tag="ACGXWR_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030599 - pectinesterase activity
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pectinesterase family protein"
                     /protein_id="HFK0802326.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6038..6916)
                     /locus_tag="ACGXWR_000720"
     CDS             complement(6038..6916)
                     /locus_tag="ACGXWR_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HFK0802327.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6903..8240)
                     /locus_tag="ACGXWR_000721"
     CDS             complement(6903..8240)
                     /locus_tag="ACGXWR_000721"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HFK0802328.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8243..9346)
                     /locus_tag="ACGXWR_000722"
     CDS             complement(8243..9346)
                     /locus_tag="ACGXWR_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFK0802329.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9420..10928)
                     /locus_tag="ACGXWR_000723"
     CDS             complement(9420..10928)
                     /locus_tag="ACGXWR_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFK0802330.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(10894..11586)
                     /locus_tag="ACGXWR_000724"
     CDS             complement(10894..11586)
                     /locus_tag="ACGXWR_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFK0802331.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11608..12582)
                     /locus_tag="ACGXWR_000725"
     CDS             complement(11608..12582)
                     /locus_tag="ACGXWR_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0802332.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIVAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            12882..13754
                     /locus_tag="ACGXWR_000726"
     CDS             12882..13754
                     /locus_tag="ACGXWR_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0802333.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14212..16410)
                     /locus_tag="ACGXWR_000727"
     CDS             complement(14212..16410)
                     /locus_tag="ACGXWR_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0802334.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16642..17634
                     /locus_tag="ACGXWR_000728"
     CDS             16642..17634
                     /locus_tag="ACGXWR_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFK0802335.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17694..19115
                     /locus_tag="ACGXWR_000729"
     CDS             17694..19115
                     /locus_tag="ACGXWR_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HFK0802336.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19108..20607
                     /locus_tag="ACGXWR_000730"
     CDS             19108..20607
                     /locus_tag="ACGXWR_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFK0802337.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20646..22040
                     /gene="uxaC"
                     /locus_tag="ACGXWR_000731"
     CDS             20646..22040
                     /gene="uxaC"
                     /locus_tag="ACGXWR_000731"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFK0802338.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22199..22882
                     /locus_tag="ACGXWR_000732"
     CDS             22199..22882
                     /locus_tag="ACGXWR_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HFK0802339.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            22884..23720
                     /locus_tag="ACGXWR_000733"
     CDS             22884..23720
                     /locus_tag="ACGXWR_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFK0802340.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            23731..25485
                     /locus_tag="ACGXWR_000734"
     CDS             23731..25485
                     /locus_tag="ACGXWR_000734"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802341.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(25761..26102)
                     /locus_tag="ACGXWR_000735"
     CDS             complement(25761..26102)
                     /locus_tag="ACGXWR_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFK0802342.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26170..28341)
                     /locus_tag="ACGXWR_000736"
     CDS             complement(26170..28341)
                     /locus_tag="ACGXWR_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFK0802343.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28552..29409
                     /locus_tag="ACGXWR_000737"
     CDS             28552..29409
                     /locus_tag="ACGXWR_000737"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFK0802344.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            complement(29480..30337)
                     /locus_tag="ACGXWR_000738"
     CDS             complement(29480..30337)
                     /locus_tag="ACGXWR_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFK0802345.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30322..33024)
                     /locus_tag="ACGXWR_000739"
     CDS             complement(30322..33024)
                     /locus_tag="ACGXWR_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFK0802346.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33037..34326)
                     /locus_tag="ACGXWR_000740"
     CDS             complement(33037..34326)
                     /locus_tag="ACGXWR_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HFK0802347.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34476..35522
                     /locus_tag="ACGXWR_000741"
     CDS             34476..35522
                     /locus_tag="ACGXWR_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFK0802348.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35524..37677
                     /locus_tag="ACGXWR_000742"
     CDS             35524..37677
                     /locus_tag="ACGXWR_000742"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HFK0802349.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38150..39601)
                     /locus_tag="ACGXWR_000743"
     CDS             complement(38150..39601)
                     /locus_tag="ACGXWR_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFK0802350.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39598..41322)
                     /locus_tag="ACGXWR_000744"
     CDS             complement(39598..41322)
                     /locus_tag="ACGXWR_000744"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFK0802351.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41315..41929)
                     /locus_tag="ACGXWR_000745"
     CDS             complement(41315..41929)
                     /locus_tag="ACGXWR_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFK0802352.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42274..43731)
                     /locus_tag="ACGXWR_000746"
     CDS             complement(42274..43731)
                     /locus_tag="ACGXWR_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFK0802353.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(43772..44692)
                     /locus_tag="ACGXWR_000747"
     CDS             complement(43772..44692)
                     /locus_tag="ACGXWR_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0802354.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44704..45651)
                     /locus_tag="ACGXWR_000748"
     CDS             complement(44704..45651)
                     /locus_tag="ACGXWR_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0802355.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46130..46849)
                     /locus_tag="ACGXWR_000749"
     CDS             complement(46130..46849)
                     /locus_tag="ACGXWR_000749"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFK0802356.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(46898..48544)
                     /locus_tag="ACGXWR_000750"
     CDS             complement(46898..48544)
                     /locus_tag="ACGXWR_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HFK0802357.1"
                     /translation="MDNQRKPSLDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            48723..49313
                     /locus_tag="ACGXWR_000751"
     CDS             48723..49313
                     /locus_tag="ACGXWR_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFK0802358.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49405..50910
                     /locus_tag="ACGXWR_000752"
     CDS             49405..50910
                     /locus_tag="ACGXWR_000752"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HFK0802359.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(50994..52346)
                     /gene="celB"
                     /locus_tag="ACGXWR_000753"
     CDS             complement(50994..52346)
                     /gene="celB"
                     /locus_tag="ACGXWR_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFK0802360.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52346..52864)
                     /locus_tag="ACGXWR_000754"
     CDS             complement(52346..52864)
                     /locus_tag="ACGXWR_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802361.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(52880..53206)
                     /locus_tag="ACGXWR_000755"
     CDS             complement(52880..53206)
                     /locus_tag="ACGXWR_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HFK0802362.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53219..55198)
                     /locus_tag="ACGXWR_000756"
     CDS             complement(53219..55198)
                     /locus_tag="ACGXWR_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFK0802363.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55219..55533)
                     /locus_tag="ACGXWR_000757"
     CDS             complement(55219..55533)
                     /locus_tag="ACGXWR_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HFK0802364.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55701..55994
                     /locus_tag="ACGXWR_000758"
     CDS             55701..55994
                     /locus_tag="ACGXWR_000758"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HFK0802365.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56072..57184)
                     /locus_tag="ACGXWR_000759"
     CDS             complement(56072..57184)
                     /locus_tag="ACGXWR_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFK0802366.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57337..58185
                     /locus_tag="ACGXWR_000760"
                     /pseudo
     CDS             57337..58185
                     /locus_tag="ACGXWR_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(58538..>59345)
                     /locus_tag="ACGXWR_000761"
     CDS             complement(58538..>59345)
                     /locus_tag="ACGXWR_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFK0802367.1"
                     /translation="GYELDATPIEFEIERSQTAVVELTKANRLTPGGVVLTKIDDQSG
                     EVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPI
                     EFEIERSQTAVVELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLT
                     TGADGKLAIDGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVAD
                     SSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT        17755 a        12139 c        10381 g        19070 t
ORIGIN      
        1 acgacttagt tatcttatca cgtctaaaaa catgtgtcaa ctcttttttg gaattttcat
       61 aaaatgtttc aatgaagcgc gacaacgttg tttaatatat cattaaaaaa aataaaggtc
      121 aagctaaaat attatttaag cttgacctta ttataatttc aacgattgtc aaaagtattg
      181 tttgcagctg tgttgccagt ttctatagat aaatcacagc ttttgaaaca taagttttgt
      241 actgcttcga ttcgcccgaa ttcttttgca gttatttggc aatgagaaaa gcagacatct
      301 tctataggct tttcaggaaa tgctactaaa tcaaaagctc gggaaggaag tgagtaacct
      361 ggagaaaggc atgcctgtac gtttttgatg tgtatgtctt tgactttcgt catttgcttt
      421 gattcaggta tttcttcagc cactgcttgc caactttctg gcatttgagc aaggtcattg
      481 ctattttttc tattgtattc attatgccag tccattatcc aagaaaaagg aaattgtaca
      541 tcaatcatat tcagattttc taccctgata ttttcgatca ctccccctct ttcttttgaa
      601 gatttcattc gaataccaca gtctgactga aaaaaatcga tatcgtgaat atatacgtca
      661 ctaactccag cactaacttc gctaccaata gttacaccgt atcctgaacg gattttacat
      721 ctagcaacct cgattcttga tgattttcga ttgactcttg caccattgcc atctctgcca
      781 gacttaatag caatacaatc atcaccacag gccaaatcac attcatagac acgcacattt
      841 gttgaagaat caatatcaat cccatctgta cttggtccat cattgttgcg gatgattact
      901 ttttctacta atacatcgtt agaataagtg atttgcaagt tccaaaaacc tgatttctga
      961 aaaatcaaat cacgaacaac aacatgttct gcatgataca gtaaacaagc gcgtggacgt
     1021 ttaatagcat aatccgcaat ccaacgaagt cccttttgat cgtattcagc tcttgtcccg
     1081 cttttttgat cttttcccca atacagctcc caccaatggt ctccttgacc gtcgattatt
     1141 ccttttcctt ctataagaat atctttcgcc gagagaacat tcaaaatcgc tgctggccat
     1201 ttcatttcta cgccggctac tcgtgtatcg atttctggaa atgcttcgat atctgttctc
     1261 cccttgagga ctgcaccttc ttcaaagata agatgactct tatcttttaa aaaaagggct
     1321 ccgactaaat aaatgccttt tggaataaat acaggtaagt gttctttcgc accttgatcg
     1381 attgcttttt gcagtattat tgtatcatct tgttgagtgt cgtttgtttt aaagttcaaa
     1441 gcattgataa tccctttttt tgtccgcaat acgtttctcc ctatctttca ttgatttttt
     1501 tcaattcttc accaataaat acagtttttg aacgattcag tgggtaacct actagcaaaa
     1561 tgattgcgga tacaaataag cagaatgctg gtaacaagtt tgccatcgta taaatccttt
     1621 cttgtactaa aactgattgg atggctccac ctgttgtaga cgattggtaa ccaatgagtg
     1681 ccagcataaa tccgcctacc gctcctgcac atgcttgtcc tacttttctc gcaaaagaat
     1741 ttactccata tactgttcca tcttctctta agcctgtctt atattgatga taatcaatca
     1801 cgtcagtaat gaatgcccag accatcaaat tgaataaacc agatcctaaa gtagcgataa
     1861 ataaaagaat cagatatacc catgcatttg ttatatgaag gaaatacatc agcaagtaca
     1921 tacatgaaga agcaagtaac gcaaatacgc ttgcttcctt tttaccaaat aattttgtca
     1981 gctttgtagc aaatggtgct aaaactacta ctgttccgta agtaaataaa agagcaacag
     2041 acattgcttg tttattatgg aagtaatcat tgaataaata agtcatattc gtcccagcta
     2101 aaatctgatt gatcacaatg aaaatgtcaa caatgactaa aataatcagt gctcgattag
     2161 ctaacaaacc ttttaccaac tgagaagcag atactttttc gtttttgaca actcttactc
     2221 tttcagtagt caatttacaa gttaacatat atgcgacaaa tgctattgca gcacatccga
     2281 ttgaaatcca aaagaaatga ttccctgaaa cgacttgttg tccactcttg ttatgggtat
     2341 acattaaaat cggaatgaag aatcctgtag ttgatccgcc aatcgcagaa ccaatgcttc
     2401 ggaacgtgga caacgaggtg cggtcattag gatttgagct aattgctgct gccattgctc
     2461 catacgggat attgattgtt gagagaaaaa tcccataaac aatgtatgaa acaaaaatat
     2521 aagcaatctt caccgtcatt ggaagatgtt ggacgaatgg caaaaacaaa atgacagtca
     2581 ctaagcaaaa tggatacttc atttttctga tccaaggaat aaatcggcca gtttctgtta
     2641 actctgagac atcacataat cttccaacca tcacatcagc aaacgcatcc aaaattctcg
     2701 aaatcaagaa taacgtacct acgattgccc ctgaaacgcc aagaacattc gtataataaa
     2761 tcatcaagaa actattgact aaacctaaaa taaaacagtt acctagatca ccgaacatgt
     2821 agcctatctt atcggaaatc ccaaattcct ttttttcttt ttttattgta tttgctgtaa
     2881 cagcattttg tgaaagcatt tgaattcctc ctacctcttc tagtaaacgt tttcaaaatt
     2941 ataactcttt ttttcttgtt tttatattca caatgttggc tttttattgc attatcttga
     3001 cagataaaaa acaaaaaata atctaaaaac attgatgcat aagattgata acttttttta
     3061 cataacaata tatacaaaca aaaaaattca ctaactagtg aaaataagtt agtgaacctc
     3121 atttattaaa gaattaaatt acagatgatc ttttccatca tacttgaaaa actcaaaatc
     3181 agcataactt cctctttttt tatttagatc atgcactgct atcccgataa aatttccagt
     3241 aaaccctcct gagagtatac acatgttttt ttgcggacct actttcttcc attcttcagt
     3301 tgatacgtct ttcaaatgaa actgtgctgt ctctttcttt acagtgactt tcaaaaaagt
     3361 cttcttttct gtgagtggaa tcgtccaatc ttctatttgt gctactccgt tttctgattc
     3421 tatcatacgt aggcattttc ccttgtcctc attccaagta acataacaat aaatataatt
     3481 ggattcattt aagtacagta ccagtccagc catctgatta aaattattag gcatgtattc
     3541 aaatgctgtc tccgcatcaa aagtaaaatc cgtttgccga atagctaaca aatgatgttc
     3601 gaaggtagat tgaagagatt caccggaaat cagacgtaaa aaacctggtc tacattttgt
     3661 atcacaccaa tcagcatttg gcaaaatgcg tctggcattc cagttcttct ttagctctcc
     3721 ttcaaatgta tccataaact gatgatcttt ttcttgttgt acctcttcat ttgtctcaat
     3781 cattatttct tccatcggag ttgtctggct atctttaagt cttaaccaat cgtcggacgt
     3841 ccaatacact tcttgaatag cggtttctct tcccaaaata gccgcaccgt ttaatggtct
     3901 ggtacaaaga tatgtcatgt accatcttcc tgacggggtt tgtactaagc tcccatgtcc
     3961 tgtacattgc aatgtagaag caggtttgtc actagctgtc agcataggaa aaccaggatc
     4021 aagctcgtaa ggaccagtaa tattctttgc tcggcaaact gtaactgaat gtcctcttcc
     4081 tgtaccgcct tctgccgtca tcaaataata atacccgtta cgaaaataca aatgtggtgc
     4141 ctccgttttc gctaattctg tacctgcaaa tattttatag atgggaccat caagcttctt
     4201 cttctctgca tcatattctt gtaatacgat accgctggat ttattcggtg tgtccagacg
     4261 ataatcccat agttcattga caagccattt ttttcccgtt tcaagatcat ggaacaaaga
     4321 aggatcaaag ccgttactat ttaaataaat tggttcggac caaggacctg tgatctcaga
     4381 tgcagtgatc aaataattgt ggacatcttt aaacggacgg cctgcacttt tgacatctgt
     4441 gtaaacaaga taaaacaatc catcagcata actgatctgt ggcgcccata tacttccatt
     4501 tgtaggattt ccttgcaaag atacttgagt ggtcaaaata tccgttgtat gtgaccagtt
     4561 gactaaattt ttcgactcat atactcggat tcctggaagc cattcaaaag aggagacaat
     4621 aatgtaatac cgctctttca ctcttaatat attaggatct ggattgaatc ctcttaaaat
     4681 aggatttttc actttgatag tctgcatgat tcaggctcct tttctcattc ttactcgata
     4741 taaactgaat gccccagctg cgaaataaaa aaatgcaaaa ggaaacgcaa taaactgagt
     4801 gccaatcaac aatatgaatc ctgttataaa atacaaacca gtggcagttg ttaagtattt
     4861 tcctttagca gtcaaaaaca atgctactgc taaaaaagca agtgaaataa acaacacaac
     4921 ggcaaacaga ccagtcatgt cctgtaataa tccaaatgta ttttctaaag acaaagttga
     4981 atgatctaca gcaagcgact gataactttt tttaaactct gacgcagaca tattacttaa
     5041 agtaactgct aacccgccaa agaaaatcaa agatagactg ccaccgacca ttcctagcaa
     5101 tagttcccat tttcttttca tttctgaacc ccctgctttt ctaaatgtat ccattcaggt
     5161 cttttgatcg atgtttcata attgttatta cgttcagaga atttgacagt ctgttcattt
     5221 ttcttgtcat cccaattatc ccaaccagtt gggtgaacat gcccacctat cttacacgct
     5281 tcaaataaga catttgcata cggacgccac ggtcttccta aatagacgtt tctagtatca
     5341 ggttctgcag tcaaggtaca gctttcaaaa cgataccctg ttttttgatt tttcggcgta
     5401 gatgctgctg tgatgtatcc aggattttta ctggctaagc tatggatatg acactgatga
     5461 aaaacggcat ctgccccacc aaatatgaaa tccaccgttc cttcaatcca gcaatattca
     5521 taggtctgac gacaatactc aggattggca gaagccggtg tacaaaaagg agtaccatct
     5581 ttttgcaaat caggcaacgg acccgtgcat aaggtatcct gataaccaga tagtcgacag
     5641 ttttttaaag atacgcgatc tcctgaattg aataaagcaa cagcctgtcc taccttttct
     5701 cctggacctg ctgtattttc gatgtgaaga ttttctaata cgacattcga tccttctaag
     5761 aaaaaagtag cacttcggaa agtccctaac tggctaccgt caagatactc ctgttttgca
     5821 aaacgattac cggagataac tactgttcct gctcccacaa gtttaaaatt ggataatctg
     5881 ctttctatat attcatcata tcttccttct tttactatca agacctttgg atggctatcc
     5941 ggcaggcctg ccaaataatc gattccttct tggatagttt caaaatccgt cggggtatct
     6001 atagcattct ttccaattat cagtttgtct ttcatcctca taaatgctcc cttatgaatt
     6061 gtttccaaat atttctcatt tcttgtgttt ccatatgacc gcctgttaaa gaaaaagaag
     6121 aaaagttttc tggactaccc attgattgat actttttgtc cagccctttt ctcagcttca
     6181 gtacgccttc gtccaagcac atcgtatcgt tttttccaac taagctaaga cgagggcgcg
     6241 gagcgatttt ttcttggatt gctaacgttg tataagctgt caatagattt ggcacatagt
     6301 aataaaaccc atgatgatct aggcggcgat gtagcaaaag tatttcgatg tccacctgtg
     6361 ccgctagatc aatacaaact ttgacacgag aatccaatgc tgtcacccac cagcttaata
     6421 agcctcccat agaaagacca atcgttgcga gccgttgagt atctgtgtct tcccttgtct
     6481 ccaaataatc gatcaagctg atcacatcat aaatacgcat tccccataac gtttttcctg
     6541 ttaataaaaa ttgtttgaac aactcgcttt cagaaatacc tccgcgttct tcaaatcccc
     6601 aagcatcaat cgaccaaaca gcatatccca ttcctgtcag tacttctgca aaagatggag
     6661 aagctaagta aggagcacca tggatcaatt cacttttccc gactgaaaaa tctccgccgt
     6721 gagaatgcag gtaaaggacc ggcggaaacg gtccttcttt ttctggataa gcatagaggg
     6781 ctggtactgt ttccaattca tttaagtaca attgatagta ttcaagcata aaaccgtttt
     6841 gtttttctcg gtataatcgt tttccactag gggtatgtct gctagatgga gcacctaaaa
     6901 aatcattcaa ctgcataagc aaagttttta cgaacaacca gttcatccat attttctgat
     6961 tgatttgatt ggaatttctc aatactgatt tctttagtat tttctaatag aaatgctggt
     7021 ccctcgtgat tttcaatcga catctggtta aaggaaacct tacccgcaaa gccaatataa
     7081 aatccttgtc tgctcatttc ctctattcct gtcatcatag caggaacacc gggaactgca
     7141 tcttgggcca tcgagacatc gatattgtca aatgtgattt cttgtatgaa ttgttccgct
     7201 aatccataaa taaaacctgc agaagcatgg acattccttg ccgtgatatt cgaaaaatgg
     7261 atccttctga atgctggtgt ccgttcatct atcggataag cctttttttc ccatacatac
     7321 ggttctttcc ctcgcggacc acagaaataa taaagattca gtataaatgg acacatcaca
     7381 ttatccatga ctatattgga tactcgaata tcttcaacga tcccgcctcg acctcgtcta
     7441 gatttcaatc gtattcctcg atcagtttct tggaagatac aatttgaaat ggtaatatta
     7501 cgaatactac cactcatttc acttcctaat acgacaccgc catgtccatg gaccatcgtg
     7561 caatttgtga tcgtgatatt ttcgcaagcg atcctttcgt acgtatcttc agtccctgcc
     7621 ttgattgcaa tacagtcatc tcccacgtca atatggcaat tactaatacg cacatttttg
     7681 catgattctg gatcaattcc gtctgtattt ggtgaatccg ctgggttcaa gatcgtcaag
     7741 ttatcaaacg ttgcattact gcaaagaatc gggttgatcg tccaacttgg tgactggatc
     7801 aatttaatat ctttcacagt aattcgatga cagttatgga aactcatcaa tttaggacga
     7861 ggataagcga gattatctgg ttcatttcta aaagtatgcc accatttttt tccatttcca
     7921 tctaatgtac cgaaaccagt gacagagatg ttctctacat tttgagcata gatacaggaa
     7981 gcataaactt ttcgatggac tccttcccaa cgtgaatgaa caacaggata atcttttgga
     8041 tcgtcagaga atttcagaac cgctcctgcg cttaaatgaa gttcgacatt gctttttaaa
     8101 aataaagctc ctgttagaaa ttcacctgct ggaacaacta cggtcccgcc tccgtcactt
     8161 gctgcagcat caatggcttg ttgtattgct tcagtattca attcatcaat tgatgcgcca
     8221 aatgtcaaaa tatcatacat atttataatg cctccacttc aatcaatgct tgcaagaatg
     8281 caccaacgcc tttttgatca ttacaaataa ttggttcact gatgtagtaa gcatatgaac
     8341 catctcgctg atctgctccg cctaaccctg ctacttgaca gtttttattc aagttcagcc
     8401 agccttcttt tgtttccaga acaaattcat caagtaatcc ttgatgtgat ttcttcactt
     8461 gtggaagcca ttcttctttg ttcagcagtc ccaaacgtat tcctttagcc attgcgtaaa
     8521 caaacatact actgccggaa gcttccagat aatttccttt ccgttttgtt tctgttgtta
     8581 cttgatacca tgtcccgctg ttttcttctt gatatggaag taatgcagcc agtgtctttt
     8641 ctagaatttc tttcagcaaa gaacaatctg tttcttcatg aagtaattca taggtatctg
     8701 ctgcagccat caaataccag ccaatcgatc ggctccaaaa atgatgggat agacctgttt
     8761 ttggatcagc ccatggttgg accttctttt catcccatgc atgaatcagc aaatttgttt
     8821 ttggatcgaa tagatgttta taactgattt caaactgtct caaaacatct tggtaatctt
     8881 tttcttcact aaaattctgg ataaattcag cataaaaagg agaacccata tataagccat
     8941 ccaaccaaat ttgataagga taaatttctt tatgccaaaa agctccttcg gatgtgcgtg
     9001 gatggtttgc caactgctgg gaaaggagtt ctgctgcttt tttatatttt tcttcgcctg
     9061 tttctttgta caataaaaag aaaagctttc ctgtatttac atggtcgata ttgtattctt
     9121 caacgctgta gccacggatc gttccatctt cttgcacgaa atagtcgata ttgtctttta
     9181 tgaaatcaaa ataaattttt tcttgggttc gttcccaaag taattggaac cctttaagta
     9241 cgacgccata gtcataagac cattttcctt tataccactt ttcttcatat aagcgaggtg
     9301 ttctttccat gatacttttt gctaatttct ttgaccagtt ttccattatt tgctctcctt
     9361 taaaaattaa aataggattt gggacaaata ccaagaagta tttgtcccaa tcgtctatat
     9421 tactgtgccg ctgctttgta tgcttcctcg tactcttgtg tgattcgatc gcctccttgt
     9481 gctttccagt cttctacagc ttttttgaat ccatcttcgt caagctgtcc catgatgtat
     9541 tgcaccgtag catcaatgac gattttttca atttctgatc ctacttcatt gttcgtcggt
     9601 gaatccaatg gcacagaagg atccattaca gcaaattctt cattttcttt gatcaattga
     9661 ttagagaatt ctttttcagg gtctgtatct ttgaaagaga acgtcacttc actaggacga
     9721 gagcttgata acggttgcac ctcttgttgc caaagatcca tatcgataaa ttcgatagaa
     9781 ccatcatcat tcaattcata atgcgttcct tcgataccgc cagtcatcaa tttatacaca
     9841 tcttcttcta aaagatcatc aacaaattga agtaatttct tcaattgtgc ttcgtctttt
     9901 acttgagatt tgggaaatgc tagcaagccg ccaataccat ttccttctga ccaaacatga
     9961 taaccgccgc cttcaccatc tgagatcttg tttacaggca ctaattccat atcatcttga
    10021 ataccttgac ccatcgtctt cagattcttg atatccacca ttccagtgta gattccagtt
    10081 cttccttgtg caaattgttc ttgctgatca gtcttttggg taactgcaaa gtcttgtgcc
    10141 aaatagccat tctcaaatag atctcttgaa aaattcaaag ctttcatata ctcttctgta
    10201 tcaaattctg gagtgaattt gccattatcg tctacagccc agccatttgg tgctccaaaa
    10261 taagaagtga aaagtttaaa gctggtataa cgaatatcac taggcgcacg atcgccaaaa
    10321 ccaactgtgt cgtccacacc atttccatca ggatcgtttt ctgtaaattg tttagctact
    10381 tcataaagct catccatggt agttggaaca tctagtccta gattatccaa ccagtctttt
    10441 cgaatgacta agccagcacg agcgtagtct ttttgtatcg gtacgccgta caaggcaccg
    10501 tcgatactcg cagcttcgat tctatcttca gaaatttgac ttaaattttt atagtctttt
    10561 aaatattctg atacatccca gaatacgcct gattttaacg cattgcggac agaagagttt
    10621 ttcaacatcg caatttgaag tgtaacgata tctcctagtt catcagaagc caatgcagtt
    10681 gttaatcttt cttcttttga agcatcagga atccagttga atgtcagttc cgtatcggtt
    10741 ttttcttcga tcaagttcac aatcgtgtct gtaggcggtg aagcatgatg caaaatattt
    10801 aaccaagtga ttttagcttt tccatcttct gtctctgaag aactgttact tgaactgctg
    10861 ccgcatgcgg caagtgctag aattcctgca aaactaagac ctaattttac gagcgttgct
    10921 tttttcataa attttctcct tcactgtttt aataatattt ttgttttctt ctgttttttc
    10981 tgtatatgag ttcttccatt ccaaatggca aaatatagaa tttgctgtcc acgtgactgc
    11041 ggaaaagaag agactgccac cgataaaggt taaaacacct ggcattgttt ggatgatcat
    11101 cagataaatc cctaccatac ttaatatcaa cactaatgag taatgaagat gtgagaatcc
    11161 gaataaaaat gccattttca ttttgaaaaa atatcctttc caatcataat gagccatgat
    11221 tgggaaaata tagagtgctg agagcacata tatgaacgca gcaatataca aagcgatcct
    11281 aagataccaa ttgtgtatga aagaaagatc cacaagtaaa acaatcccga tggcgccata
    11341 tatccagctc atcagcaagg tttcacgata gttttcttta aaatatgtga agtacgtttt
    11401 cgtcaaagga aacgtttctt ttgagcgcag ccattttcta atcactgcaa ccatcgcata
    11461 cgatgcagga ccgaaagtaa aaactcccaa acctgcgatg actaaaccgc cccacagaaa
    11521 attcaaataa accaactgta aaatacgatt tagccttccg tttattttat ctaatgactg
    11581 cagcatatct ttccctctct ttctatctta gtaaacgccg tcttctccta gctttttggc
    11641 aatcttatta gctaaaatta ccataaacaa tcctacgacc cctttaaaca atcccattgc
    11701 tgtactgaaa cttaactgtc cattcttcaa tccagctgta taaatatagg tgtcgaaaat
    11761 ttctgcaacg cttcgattca atgaattcaa taacaagtac atatgctcga accctaagtc
    11821 taatgtctga ccgattttta gaatcagcaa ggtaatgatt actggacgaa ttgccggcaa
    11881 tgtaacatgc catgttttgc gtaagcgtcc tgctccatcc atttctgcag cttcatacaa
    11941 ctgtgtatcg actgcagtta tcgctgaaag gtagatgatc gtagaccagc ccaactcttt
    12001 ccagatcact tgtccgatat atactgtgcg tgtccattca ggggatgtta gaaaactgat
    12061 tttttcaaat cccattgttg caaggaattc attcaatacc cctccgtcaa cattcaaaaa
    12121 tacataagta atcgaaacaa tgattaccca agacatgaag tgagggatgt aaatgatcgt
    12181 ttgaatcccg tttttcaatc gtttgttcgt tacttcattt aatagtaaag acaaaatgat
    12241 tggcatcgga aaaaacacga agatatttaa tccgaacaag atcaacgtat ttcttaataa
    12301 tgtaaagaat gtcggttctg taaacaaacg aatgaaatgt ttgaaaccga cccaaggact
    12361 tcccattatt cctaaaaatg gttgataatc ttgaaaagca ataacgagtc cccccatagg
    12421 aagataccta aaaatcaaga aataaaggac tcccggcaga atcatcacat ataaaaattt
    12481 attcgttttg attcctgcaa ctattttttt tcgtcttctg agcttttctt cttttttcga
    12541 tagcgtcagt tgaaatggtt cttgtttctt tacactttcc ataagcccct ccttagtttt
    12601 gtgaatgttt gctgcttatg acttcatgat agataactat ctgaattacg tatataatca
    12661 tttttaccgt aagtaaaaac gcttacatag caatgatttt tgtgctatac aaaacgataa
    12721 agtgtatttt ttcacaaata aactacgcat agcaaacctt ctattttttt ctatctgaca
    12781 cttagcatag gaaatgatta tatacgtaat ctttcaccga tgataaattg aacatataga
    12841 aacagaaaca tttaatttat tttgaggagg agcctatcta tatgaaaaag aaagtctcta
    12901 taggagaaag aagttttaca cttttcaaca atacgtttct aattttgcta gctttgatct
    12961 gtatcgttcc ttttttaaat atcatcgcta catcttttgc ttctacacaa gaagtcgtcg
    13021 cgaaaaagtt tatccttttt cctactacct tttctttaga cgcgtatcgc tacattcttt
    13081 ctacgccgac catttttaga gcacttgctg tttcgattgg tgttacaggt gtcggaacga
    13141 tcgtcagtat gtgtgcaact tcactgatgg cctacggtct ttccagaaag tatttgtttg
    13201 gtcgaggttt cgtcaacttt cttgttgtat tttctatgtt gttcagcggg gggatgattc
    13261 caacgttctt agttgttcgt tctctagggc tggtcaattc ttactgggcc atgatcctgc
    13321 ctgtggctgt taatgcaatg aatatgatca ttatgagaaa ctttttccaa gccttgccgg
    13381 atagtttgga agaatcagca aaaatggatg gttgcacaga ttttggtgta tttttcaaaa
    13441 ttatgctgcc attagcgtta ccgtctattg ctactatctc gcttttttat gctgttactt
    13501 actggaacac ttatatgact gctattttgt atatcaacga ttcatctaaa tggccgatac
    13561 agattctttt acgccaaatc gtcattgtat caagtgggat gcaagcagaa agtagtgccg
    13621 ttgatgtgat tccaccagca caaacagtta aaatggctgt tatcgttatt gcaacagtgc
    13681 ctatgctgat tgtttatcct tttgttcaga aatattttgt caaaggagca ctcgtaggtt
    13741 ctgtcaaagg gtgattatgt actgaacgca aaatggtagt tgtgtcagaa gtggtcagct
    13801 tcaagaaata agaaggcatt tacgaaaatt gcttcttaaa tttttgtgaa atttcggctt
    13861 atttttcgaa gaatctactc ctggaacacc gtgtatcaga ggttgtgaaa gagacgttca
    13921 gccttgagcg atgataaaaa ctctcacaaa cattgcgacg agtaacccac aggagcaata
    13981 agaagcgatt ttgaaaaata gcttcccata tttcacaaaa ttatgcctta ttgtcgatag
    14041 cctgtctctt gaacgccatt tattcgtaaa aaagaactgt gacaagactt ttgtcacagt
    14101 tctttttgcg tgcttagcct tgaaatttaa ctatccataa atacaaatac tagggttatt
    14161 ctaacttctt ttattgcttg aatcagtcca caagaaaaac agcctcttga ttcacaaata
    14221 tttttttcga tattctcccg gcgtaatcga ttccttcttt ttaaagaaac gaataaaatt
    14281 ttgcggattt cgatattgca atctttctgc aatctctttt acggagaggt tagtctcttt
    14341 caaccatttt tttgctacct ctaaacgatg attttgaaca aaatcaccaa atttttctcc
    14401 tgtttccttt ttaaatacat tacttaaata gttagggtta taatgcaacc tatcagcgat
    14461 cacatctaaa gacagatcac gatcatattc tgtgtagacg atatgcataa tattctccga
    14521 caaattttta aattcatgat cagtgattgc ttgagagcat tctgtgattg gcagaactaa
    14581 ttgttctaaa acaagttttt ctagttcttt gggatgataa ttgttcagtg cttttacata
    14641 aatttgtttc atgttatcaa agttttttga atctactccc aataactgtc ctaattgaac
    14701 gagttcattg atcaagcgga ccgaaactac ttcccgactc aaaggatttt tattttgtgc
    14761 aaacaatgca tcaatcaatt catgtactaa attcttcact tcctgatttc cagaacgaat
    14821 ggcttcaaac aatcgatttt gttcttctat cggatatcta ataagtgttt tttcatgagc
    14881 agcaggaacg atttcctgat aaaaaataat tgaacttgga ccagtattta cacgataata
    14941 cagggcttct tttgcccgat caaccgattg cttgctttca ttcagcgttt cgaaccggtt
    15001 actgatgcct atactgatag ttaaattcaa gtattctttt acacgttttt gaatgagtcg
    15061 gcaatactcc atgacttttt tgcttgcttc tgcatcatct ttatccattc gataaatagt
    15121 ggcttgcatt tcttcattca aaacgatcgg cagcattcga ttttcctttg gcacaatttc
    15181 cgtgatcatg ttgttgatcg ctaaaagtag caaatcacgc tccccaccgt gactatcttc
    15241 taacagatcg atttgaacca aagctgtata atagcagtca ttttgagaac tataaccaaa
    15301 ttgctgcaac cgctgatcta gttctcgcct ttctactcga tttctaaata aactaagtac
    15361 aaatagcgtt tccagctgtg gcttttgggt aactaagtgt gcacttaacg cttctttttc
    15421 tcctatgatc cgactgactg attgagcgac caaatctagt tctttcccac tgaatccttt
    15481 tgatttaaga ttcagacgtt cctgtatttg agaaatcgga cgggcaaatc tgtccgaaaa
    15541 taagtaggaa agaagaccaa tgagtcctac cagtgttaaa gacactgcaa ctagcccgat
    15601 tctcagattg cggatcattg cgccaattgc actagagtca acttctaatc tgtaaatcca
    15661 attattataa tctgatttca gtactatata cgttttatct ttttctctta tcactttcag
    15721 ctgattgtaa tctagatcca cgtccgttaa tacagttggt tgctctttat tttttactgt
    15781 ctgagtagta aaaaggttgc caacttcgtt ttcaatagaa agtatgtctt ctccactttc
    15841 accaacaact tgttctattg tatgtttctc tatcgtagca attcccaatg catatttttc
    15901 tttttcaaac attggcaaag aaatcaccat ttcgattcct ttgtttttct tttgccaaaa
    15961 taaattattt ttgttattta tgtacttctg ttgatacttt tcaatttcct cttcggtcag
    16021 ttgactcaac gatccattga ttactcccca tttaccagcc aaactgacta aatcataatt
    16081 attatcatcc ataacaatcg tttctataaa atttagttct ttcctgattt cagaataagt
    16141 ggagtaatct gtatatgtca gcggatgctt gaatatgtcc gagaaatttt tggtcgaacc
    16201 atacgtagaa aacgaatatt caatcgttct aattttccat tcaacgttag ttttaacttg
    16261 cctgagcaaa ttctttttgt ctgttaaata actcgattcg atcgattcat aggtattctg
    16321 gtaaatgaat aaactaaatc ctatgacaag tacggctcct aataaaaaca tcggtaaaaa
    16381 tattttataa aatactgtac ttttcttcat tttcttcctc tcctcctttt aaaataaaag
    16441 gctttcattt ttctgtaaaa ttgatactca tctaattaaa tgagcattcc ccgctttcaa
    16501 gaatagcata attaaaaata aaaatccaag taatttttaa cgtgtgcaat cttttcatat
    16561 caaagatcta ttgacttatc gtagttatcg taatatgatg aatgcgttaa caaaaagtga
    16621 aaaagtaagg aaaatgatgg aatggtaacg atcaaagatg tcgctaaagc agctggcgtt
    16681 tctcatacga cagtttctcg tgctttgaat aacagcagtt taataaaaaa tgaaacaaaa
    16741 caaaaaatac gacaactagc taaggaaatg aattattcgc caaactatag tgcaaaaggt
    16801 ttagtgaatc aaaaaaaata tctaatcgga ctatttttct caagtttgca taaaggaact
    16861 tcatcaaatt tcctagcaga ttccattgca ggcatccatt cagtattaga cacaaattac
    16921 agtttatctg ttgaaagtat cgatgttgtt gatttaacag aaatcaacct gcaacgctac
    16981 gatggactga tcgttatgag tcaaagtgat gatgatcagc ctttcatcga ctatctcaaa
    17041 gaaaaagaat ttcctttcgt tgttgtcaat cgtcacatca atgatccagc ggttatcaac
    17101 gtcactgccg atgatgcggc cggtgttatg caggcagtag attacggtat tggatgcgga
    17161 catacgaaga tcgcttatat tggcggaaag aaaaattttc gttcgacaaa agaacgggaa
    17221 aaaggggtat tgaaaagtct aaaaaaagcg agcatccctg tcaatccagc ctatttttta
    17281 acaggagatt acagcttaga aagcggcctc caaaacatgg aatacctatt atcactttct
    17341 gacctgccta ctctggtttt ttgcggcaac gacgacatag cgattggtgc attgagagct
    17401 gtacatttag ctggcctccg tgttccccag aacatttctc tgatcgggtt cgatgattct
    17461 ccagtcgtct cctatctcaa tccgccgctt accaccgtac gtaagccttt gaaagaaatg
    17521 tgtcaagaag gaacaaagct tttactagat ttgatcgaag gcaggacgat cgaacaatct
    17581 aaaattgagc tctccacctt gttgatcctt cgtgagtcga tcaattactt gtaaactaca
    17641 agtaatttta tataaaaatg ttaacgtgtg cataacacag aaaggaagtt tatatgaaaa
    17701 aactgacaaa agaattagtg aaaaaaaacg aagcacctgt aaaagttctt cagtttggtg
    17761 aaggcaattt tatgcgtgga tttattgatt ggcagattca gcagctgaat aaccaacaat
    17821 tgtttaaagg taatgttgca atcattcaac ctttagaaca aggtcttgga aatatgatga
    17881 accagcaaga taatttatat acggtcattt tacaaggact cagcaatggc gaaatcgttg
    17941 atacttccga gattatcacc gtagtagaac aaatgatcaa tccttatgat gaatgggatg
    18001 cttatctatc tctagcagaa aatgacgact tggcctatat cgtctccaat acaacagagg
    18061 caggaatcca attcgtggag actgataatt taacagatac tcccccacag agcctcccgg
    18121 gcaaactgac agccttttta taccgacgtt tcaaattaaa caaagctggc tttaccatca
    18181 ttccttgcga actgattgac agaaacggcg aacgtctaaa agaaatcatt ttacgctacg
    18241 cagaaaaatg ggatttagaa cctgcttttg ttgagtggtt agaaaaagaa aatgttttct
    18301 gttgtagttt agttgatcgc atcgtcccag gttatcctcg cgaagatgca ggtgttttca
    18361 atcaacggca taactatgaa gatcaattga tggtcaaagc agaaccattc atgctttggg
    18421 tgatcgaagg gcctaaagaa ttggagaatc aactaccatt caaacaggct ggcttgaatg
    18481 tcatcatcac agatgatatg actccttatc gtgaacgtaa ggtgcatttg cttaatggac
    18541 cgcatacagc gatggtccct cttgctttgt tggcggaatt ggaaactgta gaagaagtaa
    18601 tgaaagatcc tttattctcc gcatatgttg atcagttatt caatctagaa ttgattccta
    18661 tgctttcttt acctaaagat gaattagcca tttatgctga ccaaatcaaa gaacgtttct
    18721 tgaatccttt tgcccatcac aaattagaag cgatttcatt aaatagtgtt tcaaagttca
    18781 gcacccgtct gcttccagtg ttcaagaagt atatcgaaga acaaaatcag gtaccaccgt
    18841 taatcactgt ttcactagct gcgctacttc ttatgtatcg aggcgatcaa gtaaagccac
    18901 atgatgatga aaagacgata agcgaattta ctgatgcttg gtctgataat ggaacagcta
    18961 ttcctcgatt attgcaaaac gctgcgcttt ggggagaaga tttgtctcaa ataccgaatg
    19021 tgacagatac agttcaagaa atagctgcaa agatcgatca aaaaggtgtc cggtcagtat
    19081 tacaagaaat gaaaggaacg atggtccatg cttgaaaccc tgcaaccaac aatgaaatta
    19141 aatcgacgag acagtgtggt cgtcgcatta acccctattc caaaacaaac acaactgacg
    19201 attgatcagc aaacgatcac cactcttgaa gatatcccgc aaggtcataa gattgcattg
    19261 ggtgatttga aagctggaga caacgtgatc aaatatggct atccaatcgg tcatgtgacg
    19321 acagacgtaa ctgccggtca atggctgcac actcataatg taaaaaccaa tctttctggt
    19381 gaattggatt atcgatatga aaaagatgtc catccaagtc attacctttt tgagaaccga
    19441 acatttcaag gttacttgcg aaaaaatgga aaagtaggga ttcgtaatga tttgttttta
    19501 gtacctaccg ttgggtgtgt gaatggcatt gctgaactga tcgtcaaaca gttcaaggaa
    19561 aaacatccag atctgggaca gtttgaccat attacgattt taaagcatcc ttatggctgt
    19621 tcgcagcttg gaaaagatca tcaaaatact cgagaaattt tagcggacgc agtaaatcat
    19681 cccaatgccg gaggagtttt agtatttgga ttaggttgtg agaacaatac agttcctgaa
    19741 ttcaaaaaaa ttttaggtga atatgatgaa gaacgagtga aatttctagt ggctcaagat
    19801 gtttacgatg agatcgaaca aggtgtggct ctattagaag agcttttaac agcggcggaa
    19861 aatgaccagc gcatatcagt cccgctctct aagttgaatg tcggtttgaa atgcggcggt
    19921 tctgatggtc tatcgggaat aactgctaat cctttacttg gtgcattttc tgactacttg
    19981 attgctcaag gaggcagcac gatcttaaca gaagtgccag aaatgtttgg cgcagaacaa
    20041 gtattgatgg cacgagcgga aaatgaagaa gtttttgact caatcgttga cttgatcaat
    20101 gacttcaaac agtatttctt gtcttacggg gaaccagttt acgaaaaccc atctcctggt
    20161 aataaagcag gtgggatcac tacattagaa gataagtctt taggctgcac gcaaaaatca
    20221 ggaagctctc ctgtcgttga tgtgctacaa tatggcgaaa aaatcagaaa accagggctt
    20281 agtttattgc aagctcccgg gaatgatctt gtagctgcct ctgctcttgc ttcatccgat
    20341 tgccagttgg tcttgtttac cacaggaaga gggactccgt ttggctcata tgtcccaacg
    20401 gtcaaggtat ctacgaatac aactcttttt gaacgcaaag gtcattggat ggattttaat
    20461 gcaggcgtct tattagaaca accaatggaa gtaatcttag aatcgtttgt tcaaaaaatc
    20521 atcgctgtag ctagtggaga agaaacgaaa aatgaacaaa atgacgttcg agaaattgcc
    20581 atttttaaaa acggagtaac actttgattt tcataaaaca gtataaaaag aaagaaggaa
    20641 gatttatgtt tttatctgat gattttttat taaaagacga ttgggcgaaa aagctttacc
    20701 attcctacgc aaaaaacatg cccattattg attatcactg tcacttagat ccaaaagaaa
    20761 tttacgaaaa caacaatttc agcaatctga cagaagcttg gttaggaggc gatcattaca
    20821 aatggcgctt gatgcgagct tgcggcgtgc ctgaagaaaa aatcacagga aatgcttctg
    20881 attttgaaaa atttttagct tggtgtcaaa ccgtaccaaa aattatcgga aatccgcttt
    20941 acagttggtc acatcttgaa ttgaagcgtt tcttcggtat tgacttgttg ataaatgaag
    21001 aaaatgcaga gaaaatttgg acacaagcaa atgaaatttt ggcagctcct gattttcgcc
    21061 gtcgggaaat cgcaaaaaaa tcgaatgtag aagtgatttg tacaacagat gatcccgcag
    21121 acgacttgca ctatcatcag ttgcttgctc atgaagaacc agatttgaag gttctacctt
    21181 cattccgtcc agataaagca ctcaatattg aaaaagaagg atttaatgca tgggtcacac
    21241 tactggaaga agcagctgac caaacgatca ccacctatca agaactgata gaagtcttag
    21301 ggcagcggat agaatacttc catcaacatg gatgtcgtgt ttccgaccac gctttagaca
    21361 tcttacgcta taaagaagcg gatgaaacag tattagaaga gatttttcaa aaagcacgag
    21421 ctaacaaact attatcttca gatgaaatcg atgcttatcg tacagaaaca ctgatacatt
    21481 tgacccactt ctatcattct cataattgga cgatgcagct gcacatccat gcttatcgta
    21541 actgtaatac acaaatgttg gaaaaattag ggcccgatac cggctatgat ggaatgaatg
    21601 atctttcttt gactattcct ctgcaaaaat tattgaaccg tgcagaagaa acggatcagt
    21661 tgccaaagac gatcctttat tcattgaatc cgaatgacta tcctgcgatt ttagctttga
    21721 tgggctgttt ccaaaaagaa cagaatggaa aactgcagtt aggttctgga tggtggtaca
    21781 acgatactcg agctggtatg cgcgatcaat tgacacaatt tgctgatggt agtgctttgg
    21841 ggaattttgt cggcatgctg acagattcaa gaagtttcct gtcctacact agacatgaat
    21901 atttccgtcg tgttctttgt gaatttttag gcgaaatggt catgcgagga gaagcacctg
    21961 aagatgaaca acttttagga agtctagttc aagcgattag ttatacaaat gctaaaaatt
    22021 actttggctt ttttgcctaa ttgattaata gtaacagtaa cgaatcaaaa acaggatagt
    22081 gaaataacgg aatccgttta tccacgtttt agagaagaag acggaccaaa tttgctccgt
    22141 cttcttctct tgctgttctg cttcattgcc tataaacctt tatgaaagaa gagataacat
    22201 gcctactatc catattgccg gtgattctac tgcggcagaa aaagatgaaa acaagcgtcc
    22261 cgagacaggt tggggagaaa aaatctctgc ttatttttca cccgagatcc agatcaataa
    22321 ccaagcaaag aatggacgca gcaccaaatc atttatccag gaaggaaggt tagcccgtct
    22381 agcttcacag tttcagccga atgatttctt atttgtacaa tttggacata acgaccagaa
    22441 aatccaagaa gaaagaggta cgcttccctt cggtagctat ttaaaaaatc tgcagatatt
    22501 ttttgaatgc gcaaaaaaag cgaacgtcca aatggtctta ctgacatctg tgacgcgacg
    22561 agattactta gaaaacggaa cattgaatcc agatatactt ggagactatc caaaagcgat
    22621 gcgtgcattt gctgagaaac accatattcc tcttttagat gtgttctcaa gatcacaaga
    22681 attgttccag accttctcaa aagaagagac aaaaaaattc tacctgcatc ttatacctga
    22741 tacttgtaaa aattacccag aaggactaaa agacaatacc cactttagtc cagaaggcgc
    22801 tgataaagtt gcccgaataa ttgttgaatt gataaaagaa tcccgtctgc ctcttgctaa
    22861 ttatttacaa aaaggagttt gagatgtttc cattaaattt aggcatccgt gcccacgatt
    22921 tagatgttcg aaatcgtgaa gaaatcgttc aaaaagtatc acagcttcac ttgtcccata
    22981 tccaatttgc accacaaaaa gcatttcctg aacaacttaa attaactgac atgacacttg
    23041 ggagtgctgc ctattttggt gaatacttcc aaaaaaacaa tatcgaactt tccattttag
    23101 gatgctatat caacctatcc agcaaaaatc aagaagttcg tgcacaagca ttggcaactt
    23161 tcaaacagca aattgctctg tgctctgcct atcaagccaa gatgattgct acggaaaccg
    23221 gtagtgtctc tgtcggttac acaaaagaaa attttactga agaagcttat cagatcgcca
    23281 gaaattctat cattgaatta gtcgctcatg cagaaaattt tggcgtaact gttgctgttg
    23341 aagcagggat caatcatcca atctataact atcagttagc taaacgttta atcgatgaag
    23401 tagcttcacc aaatttaaaa atcattttag attgtgcgaa tttgatgcat aaagaaaatc
    23461 atgctgatca ggaaaaagtg atccgaggtg ccttggacaa tttacatggt tatattacag
    23521 cgcttcatct caaagactat atcatggaaa atggaaagat ccgcatggta cctgttggca
    23581 agggctgttt agatttccgc ccggtactgc attatatcaa atatgagcgt cctctaatgt
    23641 acgccactct tgaagctact cctgagattt atgttcctga agcaatagaa cacttgcagt
    23701 ttatttacca agattgttaa ggagaagatt atggaggaac gaatacagaa aagttatcaa
    23761 aaatatcatg caaatgcttt tcagacattg ctgcatcttt atcagggaaa ttattggcgt
    23821 tttgccatgt caggactctt ttttattatc aaacatcttc catcttggtt aatgccgatc
    23881 gctattgcca atgtaatcaa tgcagcttca tcgaaagatt cttctcagtt gcaggccatt
    23941 tatttcaacg cttttttgat ggcttgtctg attggtcaaa atatattgac gaattatttt
    24001 catgtaaaat accatagcac ttcgatccgt caagtagaag ctggactaag agcgaccctt
    24061 atcaagaaaa tccaagaact atctattcct tatcaaaaag aattgcaatc tggacgaatc
    24121 cagtcaaaga tcatccgtga tgtagaagct atccaaacgt tgtcctctca agtatttgtc
    24181 agcggattaa atatcgctgt caatttattc gtagctttag gtatcacgct ttataaaagt
    24241 cctgttgttt tcatgttttt cttattgact gttcctctcg ccgcattcgt tactctcttt
    24301 ttccgtaaaa ggatcagaca gtccaactca gacttcaggc aagaaatgga agagacttct
    24361 gcaaaagtga tcgaagtgat cgaattagca ccgattgctc gagctcatgg gttagaaaaa
    24421 cacgaaacaa ctcgcttaaa taagcatttt actcaaatct atgaaaaagg attccactta
    24481 gatatcctgc aatctgtttt cggatcagtc agctgggcta gttttcagat atttcagctg
    24541 atttgtttga ttttcactgg gatattagct ttacaagggc gcatccaacc cggcgatgtc
    24601 gtgatgtatc agacgtattt cacgacgatc gtcaattccg tttctggaat gatcacgctg
    24661 attcctacga tttcaaaagg catggaatct atcacttcta ttggcgaact gttgattgct
    24721 ggcgatgtag aaacttatca cggtaagaaa aaaatccaac atttggatgg aaattttcgt
    24781 tttgaggatg tttcttttct ttatccggac tcactcaaac cgattatcga tcatttttct
    24841 ctagaggtga aagctggaga aacaattgct tttgttgggc catctggctc tggaaaatct
    24901 acactcctta acttattgat tggatttatc cagccgactt caggaaaaat ttttctagat
    24961 gatcagcctt tggatgaact ggatatgcga agtgtgcgaa attatttagc cgttgttcct
    25021 caaaccactt tgttgttctc cgcttcgatc aaagagaaca tcacttatgg cttgaaaaac
    25081 gtatcaaaag aacgtttaga tgaagtcatc gaagctgcgc aactttcttc actgattgac
    25141 cagcttcctg atggtctgga taccttagta ggcgaacatg gcaacaagct gtctggtggc
    25201 caaaagcaac gtatctccat tgcacgagcg ttgatacgtc agccaaaaat cattttgcta
    25261 gatgaagcaa cctcagcttt agataaccag tcagagaaaa aaatccagca agccctgaat
    25321 tacctgacag aaacacccac tacttttatt gtggctcatc ggctttcaac gatcaaagag
    25381 gcagataaaa tcgttgtgat cgatgaagga aaaatcgttg aaataggtac ttacgaaaaa
    25441 ctgttagctc aaaaaggcta tttctaccgc ttgaaaaatg aatgacaaaa aataggagct
    25501 atgacaagac ttttgtcgta gctcctattt ctgaataaac ggtgttctcc tgccaactcc
    25561 tcggtcacaa gtcacaatag tcatcaaaca tgagaagctg ttttttgaaa ttgttccttg
    25621 taactcagag ttaaacggta ggctcacgac ctcttggtaa atggtgttca agagacagcc
    25681 tatcggcaat aagaagcaat tttgtcatcg ctcaaggccg aacgtctctt tcacaccctc
    25741 tgttgtttca taaaatagtt ttattcgctg taaaggtcgc gaactggtgt catgatgata
    25801 cggttcaagt cattgatgat tgtactgaag ccttgctctt tttgcatcaa gtcattgatt
    25861 acttcttctg attggatttt cacagccatt tcttgtgctt tcattgcatc ttcgtcgctg
    25921 aactcttgtc cactcatttg tttttcttgt aattcgattt gcatcgcttg gaagtctttg
    25981 aacagtttgt gtgcttcttc gtttgcttgt actttctcgt acgcttcttt caacgctttg
    26041 aattctggta attcacggat ctcacgttcg atttgattcg cgctatcgta gatgtttgac
    26101 atgttatgcc ctcttttctt ttagtagtta ctctctattg taacatgggg ttattcgttt
    26161 tcaaaggggc tactctcctt gatatttccg ccagaggtct ttagccgctt caccaattcc
    26221 ctgaacgcct tctttcacca tatcgccgaa gtttttcagc ccttcttttg cttgttcacc
    26281 atattgattc aagttatctt gccaatttcc agactctcca ttagaatttc ctgtgtttcc
    26341 aacttgatct gcagctacca cttgtcctcc tgtggcatag gcatctgcta cactaaatcc
    26401 tgtttttgaa gtatacggaa ggatgccttc tgccgctgat ttgaagactt tcccgacaac
    26461 atttccactt gtcccttcca aatagtgcag cttgctggat tcttcgtaac ccatccatgt
    26521 cgaaatcact acgtctggcg tgtaaccgat catccattgg tcatttgctt ttgtggcatc
    26581 gaaattagtt tctgtggttc ctgttttccc tgctatcgta taacctgcag gattcgcagc
    26641 agccgctgtt ccatttgaaa atgtaccaag aagcatgctg gtcatttcat cggctgtttc
    26701 ctttgatatg acctgttttg gttttttgtt tgtgttatcg acgatcaccg ctccagtcga
    26761 atcaacgatt ttcgtgataa gatgcggcgt atacatctga ccatcattgg caaatgcact
    26821 gtaagcaccc gccatgatca atggagatac tcctttttcc agtccaccaa gggctaagcc
    26881 ataatactta tcagattttg ctaaaggcag gccgaattct tctgctttat catatccttt
    26941 ttgtaaaccg atctcatgca aaagccatac agtaggcaaa ttcaaacttt gtgcaacagc
    27001 ttgatacatc ggtacttctc cttggtatgt cccgtcaaaa ttatgcgcat cgtaataact
    27061 ttgcggttcg tctttcaaga tactggaagg cttgtatcca gcttccagtg ctggtgtata
    27121 tacgcttaat ggtttgatcg ttgatcctgg tgaacgacgc atctgtgtag caaagctgaa
    27181 tcctctaaag acatgatctc ctcttcgtcc tactagtgct tgtacaccac ctgtattcgg
    27241 atctaaagct actgaagcag attggaccat ggcaccatct gaagcatttg ctgggaataa
    27301 tgcactgttt tgataagtag cttctaattg cttttgataa tcctgatcta aagctgtata
    27361 gattttatag cctttattca tgacatcttc ttcatcaaga ccatactcgt taactgcttc
    27421 atcgatcact gcatcaaaat aataaggata acgataacca gaatctgaat tatcgtatgt
    27481 gtcattaaga tacgcgctga tatctgtctg gctttctgct tgttcttgtt cttttgtgat
    27541 ttttccgttt tcttccatta cacttagtac tgtgtttttc cgatcattcg cattttttgg
    27601 gtgatcgatc ggattataaa taccaggacc tttcagcatt cctgccaaag tagcagcctc
    27661 agacagcgta acattcgttg catctactcc aaaatacttt ctggaagcgt cttggacacc
    27721 ccataccccg ttgccaaaat aggcattgtt aagatacatg gtcaagattt cttctttgct
    27781 gtacttcttt tcgatctcga ttgccaaaaa taattccttc gcttttcgat caaacgtttg
    27841 gtctaatgtc agatacgcat ttttggcaag ctgctgagtg atcgtacttc ctccgccccc
    27901 tgatgttccg ccagacaaga ccattcggac tgctgcacgg gcaatccctt tgatatcaaa
    27961 cccgtgatgc tcgtaaaaat tcctatcttc tgtcgagatt actgcatctt ggatataggg
    28021 agaaatcgcg tttaattcta catatgttcc tttttgggcg tacagtgtgc cagcttcttc
    28081 gtttttctta tcataaatga ctgtcgattg gcttaatcct gattttaacg tttcgacatt
    28141 tgcttgtttt gctaaaataa agaggtagat acttgtcact aagacacaga tcaaaccaat
    28201 cagcaaaatc aatttgttca catgatattt tttccagatg cgctttcgcc atcgatggaa
    28261 ttgtccgaga tatggtctga tccaacgcca aaaactgatc aaagcagctt ttatcttttc
    28321 taaaatgctt tgaaaatcca tttgcttctt ctcctgtcta tttgattcaa tcgtcttatt
    28381 ttaccatagt gaaagagtgt tttcttcctg cttaagttgt agttcaatat gtttttttac
    28441 gttagtgcaa gtagagtaac ataagaatga acagaaaaat gtaagttttt tcttaaatat
    28501 gttttaaaaa tggtacaatt agtctgcgat tgcactgaaa ggagtacact tgtgaaaatc
    28561 acgatcactt tacctatgaa ccatcctgaa acaacaattc gcgacttgct tgaaaaggaa
    28621 tggttagttc ctagaaaggt tcgacacttt ttgcgtatac gtaaaaacgt ttggatcaat
    28681 caacaacctg ctttgttcca tcatgaagta aagggcaatg accagatcac attgttattc
    28741 gaagaaacag attataatta tcaagaagtt caattaggag atgcgaagca catccgtgtt
    28801 ttatatgaag atgagcattt gattatagtg gataagcctg caggaatgaa gactcatcca
    28861 aatgaaccga cagaaaacag taccttactc aatcatttag ctgcttatct cgacactaaa
    28921 cagcaacgac cttacgttgt ccaccgcttg gacaaagaaa caagcggtgc cgttttattt
    28981 gcaaaaaatc catttgtctt gccgatactt ggaagaatgt tggaacaaaa aatgatctat
    29041 cggagatatc aagccatcgt atggggagaa attgccaaag atatgaccat caccaataaa
    29101 attggacgag atcgccatga tcggagaaaa agggtcgtag atgataaaaa tggtcagagc
    29161 gccttgacac atgtcactgt caacaaagta ctttctgaac aaacacaagt ctattgtgtt
    29221 ttggaaaccg gacgtacaca ccagatcaga gttcatttag ctcataaggg acatccgatc
    29281 gttggagacc ctctctacca aaatagaaca gctgaacgac tgatgctcca tgcattagaa
    29341 ctgcacatga tccatccatt tactcaagaa aaaatagtcg gtaaagcttt acctggatta
    29401 tgggaataga aataaaaaag aacagagtct tatcagcaga taatgataag actctgttct
    29461 ttttgtgtaa tttgtctgct tacttttgat gttcgtgttc tgctaacagc aaactaccga
    29521 taatcccact ttcattcggc agtccccaac gaacgatata ttcacttact tgaggtgttt
    29581 ccatataacc acccatcaat tcaacaaatt gctgacggat tttttgaagg agatgatcct
    29641 gattcattac cccaccgcct aaaataatct tttcaggtgc taacgtcaac gtatagttga
    29701 tcagtgcttg agcaatataa taagcctgaa tagcccaaac aggatgatct tgcggcagat
    29761 cttgcccttt gatccctgtg cgtgcctcaa tagacggtcc tgctgctaat ccttctaaac
    29821 aatctttatg ataaggacaa gtaccttcat aatggtcatc tggatggcgt ttcacccaaa
    29881 tatgtcccat ttcaggatgt gcgatccctg aaaaaatttc ttcattgatc acgacacctg
    29941 caccgattcc tgttcccacg gtaaggtaaa tacaactatt ttttccttgt gctgctcctt
    30001 gcttcaattc cccatatgca gcagcattga catccgttgt ccaagcagca ggaatattgt
    30061 agcgttcctt gattgtgcca agaaaatcga attgtgccca cccttttttg ggagttgcca
    30121 aaacgtatcc gtaattatct tttgttttgt cgataccaat cgggccgaat gagccaatcc
    30181 cgattccctt caattcataa cgatcaaaaa attcaaatac ctgatccaat gtttcttctg
    30241 gtgttgtggt agggatactt aatttttcta aaatttctcc accatctgaa accgcacaca
    30301 caaattttgt tccgcctgct tctattccgc catacattcg ttttcctcct cgaatccgat
    30361 tgtccgaatc tcataaggtt ggattattgg gacaaccgct tgcttcgttg gttcttcaag
    30421 cagattcaat atgacagttt ttccattgtc tttagttatt tccaattttt ctaaatgact
    30481 agacatattg aaacctctta ctactacttt atcactaaac ttgctgcgtt tcaaagctgt
    30541 aattgcaaac gtttcacttt ttatcgttaa atattgttgt tttgaaatca atgttccttc
    30601 atgatgtttg atttgttgag tggaaaaagg aatctgtgct gcgtatgcat gcaaataagt
    30661 agagaatttt tcttctggtc catgtagttc aatgctgtaa ttgaaccgat gctcacctag
    30721 acactgtgct tctggtgttg gaaaatatcc ccaatcgcct agttctccca cactgcgaag
    30781 tagcgtcact gcgatttgtc cgtcttctgt tacttcatat tcattcaaac caaagtttcc
    30841 gactgttaca ccgtactctt catcatgaat attgacaaat gcttgctgat gttgcggatt
    30901 cgtggggttt tcccaacttt tagacacatg gtttgggcgc ttcaccactt caaaaatact
    30961 atctgcttcg tgatgttcca catgtaactt tgtaggaaac aagacacgta agcgatgatc
    31021 tttcatctga ttgtcgagag tcgtttcaaa gtcgattttt ttactatctt ttctgattgt
    31081 catgattgtt tttatttgaa ggattcgttt ttctttggat cgttctgctt ttcgataacg
    31141 aaattccaca accatctgct gttctttttc taaacgctcg tctgcagaaa cagggatttc
    31201 catttcctgt agaatactta tttttgctat ttccggtgta tctactaata cttttacttc
    31261 agagttttct ttgttactgg ataggattgg ctgatcacag aaaggttgtt taaagatata
    31321 ctcatttcct atatcgccga tatcttcaaa aatatgcaga ttattcaact ttcgtttgtt
    31381 tttgcgatct tccattgtaa tggtaccatt tttttcaatc gtcaaatgta gagggccgtt
    31441 ttcgatgatt cgtccactct gatgaatcat tgtttccttt tcttctgctt tcgcttcccc
    31501 ttctacaagc gcgaatgttt cccaagaaaa tgctggcatg ttttctaatg gtaaagtcac
    31561 tttgatcatt cttgccatat atggcacacg gaaacggtct ttcggcaaat cataaccaaa
    31621 ttggacagtt tcttcagata aaatagctgg tatagtggcc ccactttttg tttctacatg
    31681 atacttacgt ttaggcaaat tttctaactc ttgatatagt tgttcaggta ttccttcagc
    31741 gaatcttttt ctttctaatt cgatggttat ttctgcttca ccagttttat ccattcctgc
    31801 agtatttaca atgacaaatg gaaagctgtc ttttgggaat ccggtcgtat cgattgctgc
    31861 ggtcagctgt tctaaggaat cttgtgcaag atactttcca acttcatctg ctttttcaaa
    31921 acgaggtatc atttcccgat ggacagaatc gactgaacaa ccgcaaatac tgtcgtgagg
    31981 atgattttgc attaatgtct tccaagcata atctaattga tcatggggat agtttccact
    32041 aacttcataa gccatcgtcg caagtggttc tgtaatattt tctagctgtc gctggacctt
    32101 ggtattccat tgttttaagt aaacccgagc agatgctgta ttggctaaag tataccagcc
    32161 atccgtttct tgacttgtca attctccttc tactgagcct aagtcttctg gcacatcttt
    32221 ttgaactgct tccagatagt cagtaaaatt agaatgaata aactcgtaat ctggaaacag
    32281 ttcatttgcg agatggattg cttttgatat atctttttgt accggttgat gatcaacacc
    32341 attcatcatc aataagtggt tcgtagaggc atattgttct gcatccgcta atttttgctt
    32401 ccaaaaggca agagctgctt ctttttctac tggaatctca ttcccgttgc tataccaatt
    32461 ggcaaatagc agaccaaaga ttgctgtttg atcaggtcct ttccaccaca tctctgagta
    32521 ttgggaagaa tagttttctg cttccaaaac ttgattatca aagccaattg gttttacacc
    32581 acggccaaac gctgctgctg aaataccagc ttgtttcatt aattgaggcg tctgtcccat
    32641 atttccaaat gtatcgggaa aatagcctaa catgacaggg gttccccatt tacggctttc
    32701 ttccatgcca atcagcatat ttctcacgtt cgattccgag ctgataagaa aatcatcttg
    32761 caagatataa aatggtccaa ttctcaattt tccttcattg attgcttgtt ggattgcctg
    32821 tcttttttct ggccttactt gaagatagtc atctaaaata atcgtttgcc catccaaatg
    32881 aaaactgttg aaggacggat caacttcaaa tagctctagt agatcgtcta tcaattcaat
    32941 cagtcgcatg tgatgctgtt cgtaagccat gtaccattca cgatcccagt ggctatgaga
    33001 aatgatatat actttctttt tcatttacga tacctcctac ttttctactc taatatcaaa
    33061 gtaatccatg actaattcgc aaaacatcat atttgcccaa gaaaaccatt ctctcgtata
    33121 attttcagga ttgttcacat cgaatccttc gtgcataagg tgtgttcctg cgtcagttgc
    33181 tacaagtaaa ttcaatatcc gctctttttc agatttgtct gacgttgtca ttccttccat
    33241 agctaatgca atcggccaaa cgtatttttc tggcgtatgg gaggatccaa ttccttttgc
    33301 gtactttcct tcatagaaat atggattttc tttactcaac aatgttcttc ttgtttgcag
    33361 ataatcttcc tcttgttcag aacaatatcc caagtaaggt gcggcgatca gattgggcac
    33421 attactgtca tccatgactg tggcgtttcc cattccatct acttcatatg cataaatcgt
    33481 ttgccctttt tgattaaccg ttcgtccgtg attctgaatc ccctcttgga tctctttctt
    33541 caatttctgt gtttgctgta caatttcttt atcatcgagt atcgtttgaa aaatttcttc
    33601 cacataacct aacacgacca ccgcaaacat attggatggt accagatatc cataacggca
    33661 agtatcatcg ctaggacgga aaccagacca tgtcattcct gtaaaagctg tttttgcacc
    33721 tcgcccgtca ttgatcagcg tatcttcttt tcttgtcgtg tctcgtacaa atgtataagg
    33781 agagtgttca tgatcttgct ctgttttgaa cacgtccaag atttttttga taccttcaat
    33841 aaaagattga ttgaattgat cagtttttcc tgtatttttg taaagaagat aggccaactg
    33901 tattgggtag cataaagaat caatttcata ttttctttcc cagatccaat cgttcatttt
    33961 tgtatgatct gtttggtggc cagcaccgtt agcttcttcg ttgaaggcat tcgcatatgg
    34021 atcgatattg atataaaaaa attgcttttt gactaacccg ctgatcatgt cagctaattc
    34081 ctcatcttct tttgcaatca ctaaataagg acgaacttgt gcagtagagt ctcttaacca
    34141 catcgctgga atgtctcccg tcaataaaaa ggtggttccg tcattttgct ttttgactgt
    34201 tgtcaacaga gtattggcaa atgctgctgt aaaattcttt gcccagtccg catggatatc
    34261 cccacatttt tgtgtgatat cttccataaa tttctgcacc gattttggta tatctttata
    34321 agccactaat aaaaccttct ttctatttga tatatcttta aagattatac ttcatacagc
    34381 caattatgtc tacgctttca aaaaatatct ttttatttac tttttcatcc attatggtat
    34441 tatttgaata tgatatatca ttaagaggtg tttatatgaa tcaaccattg taccagacaa
    34501 tatttaatga tttgcaaacg gctattttaa ctggtgaatt acctgtagac agccaactac
    34561 caactgaaaa agaactttca cgtacctata aagtaagcag aatcacttcc aaacgtgcat
    34621 tgactgaatt agagcaatta ggacttattt atcgcgttcg cgggaaaggc agtttcgtta
    34681 aatccgcttc tccggaacag attcttgctt ctcctacaaa aacacgacgg attctgtttc
    34741 ttcttccata tgtcgctgat ttgtctgttg gtgattttag caagggattg aaccctgtga
    34801 tgcaagataa acagattgat gtcatgatga cgacgcttga ctttctacaa aataaaacag
    34861 caaaagagct aatcaatgaa tttgacggat tgatttatta tgctcttgat acagaacaac
    34921 atcttgactt actttttgag ctttcattga aagaattccc tgtcgtcata ttagataaaa
    34981 aaatctatga gttacctttt cctaccgttc tttccgataa tttccaaggc ggtgcgcttg
    35041 ctgcctctta tttgatcgaa cagggacatt caaaaatcgc ttatttgttt ggtacgcaga
    35101 ctcatccaca atccgttcga cagcgttacc ttggttacct tgaagcattg gacaaagctg
    35161 gtttgacttt ccacacttca ctggatgaca aaagcgcgac attagatgaa ttgctttctt
    35221 atatcactaa gtatgaagta actgcttttg tttgtgaaaa cgatgttgtc gctatccaga
    35281 ccatgaatct cttgagacag catggttatc atatccctga agatttttca attatcggat
    35341 ttgatgatat ccaagcagca gctcttgttg acccgccact gacaaccatc gcacaagatt
    35401 ttgaacagtt aggtaagctt gcgggagatg ctttggtcac ttggttagag acaaaagatc
    35461 gaccatccga tagtaaattt ccagtttcat tcatcaaaag acaatcaaca aaggagaaat
    35521 aaaatgaata tcggtcaaat agatactaga catgcaacag cgaatcagcc aaatttctct
    35581 aatgggaact gccagcctta tactggcgtt ccttttggga tgaattattt tgcaccgcaa
    35641 actacggatc aaaacggcag ctggtggttt catcctgatg accgcgtttt tcaaggctac
    35701 cgtcttaccc atcaaccaag tccttggatg ggtgatttca gtcatatgct gtttacgccg
    35761 atcaatggaa aactacagga gaacaccctt ttccatgctc aaagttctta ccgcccagaa
    35821 gaaagtatat tttgcccgac tcatctgtcg atctgtcaat tacgttatgg catctgttct
    35881 acattgatac ctagcatgta tggcggaatc ttatctattg attacagcaa aaatgacagc
    35941 ggtttacttt tatcctttcc gggacgccat cagctctttg ttatagatcc ttacacagtg
    36001 gaaggaaaaa tcacacattt tgctggttca gaagatcctg atttttcttt ttattttata
    36061 ttgagatttg aatatccttt aacaattgat gagttagctg tttccaacaa aaatagcgac
    36121 tcgatcccgt tgtattttga acagacaaaa aaacaaacta tccgatttgg gacatctttt
    36181 atcagctcgg aacaagcagc ttataacctg gaactagaac aaaaccaaag caaagagact
    36241 taccttgctc acagtcaaga acaatggcag tcctattttg atcgtataca gctcacacac
    36301 catgatcaac aacaattgcg gacgttttat cataatttat atcgggtgtt tttatttcca
    36361 caaacatttt atgaaattga tcctagtggg caaaaaatcc actatgatac gactagtcga
    36421 tctataaaac ctggtgttct ctatacaaat aatgggtttt gggatacgta taaaacggtt
    36481 tatcctcttt attctttgat tgctgtagaa aaatacgaag aaatgctgga aggttttttg
    36541 aacagctata gagaaagtgg ctatttgcca aaatggctgt ctcctgatga acgtggactt
    36601 atgcctggga cattgatcga tgcggtcatt gcagatgctg ctgtaaaaga tatccgacga
    36661 gacttgatgc ctgaatttct aacggcaatg gaaaaaggtg ctacggttca aagcaaacat
    36721 ccaaattatg gacgccaagg aacagaagat tacttgacat atggctatgt tcctaatcac
    36781 taccacgaat cagtcaatca cacattagac tatgcttata gcgatttttg tattagccaa
    36841 gttgccaagg tactagaaga agaggaaatg acgaagaaat atcagcagca atcattgaac
    36901 tatcaaaata tctttgacta tgagtcagga tttatgcgtt caaaagataa agatggcaag
    36961 ttcagagaac cattttcagc taatcgttgg ggacaagatt atgcagaagg aagtgcttgg
    37021 caaagcagct ttgctgttta tcacgatttt tcaggactga tcggaaaata tggtggcagt
    37081 gagagatata aagaaaaact cattgagctg tgcaatcagc ccccaacgtt tgacccagga
    37141 ggatatggtt ttgagatcca cgaaatgagt gagatggccg cgatagaatt tggacaatta
    37201 gctatttcaa accagccaag ttttcactat ccttacttgt tcagttatat aggacaacct
    37261 gaaatggcac agccactgct taaacagttg atgactcaga ccttcgacga ttctccaatg
    37321 ggttaccctg gagatgagga caatggaagt atggccgctt ggtatatctt caatagtctg
    37381 ggattttatc ctgtcacgcc tggaaccggt gaatatgtta tcggtatgcc attaattgac
    37441 aaggctgttt tgcttttgtc aaatggaaag gaattgacga ttgaagcaac gcctaatcgg
    37501 ccgcagcaac aatttatcca taaaatcaaa cggatggaca aagaatatac gaaattatat
    37561 tttacccatc aagatttgct gaaaggcggc acgatctctt accaattagg gatcatccct
    37621 caccctaaga aatatcaagc aaaagatttg cctttttcct tatcaaacta taattaacaa
    37681 gaggttgtga aaaagctgtc ctgcatcaag taataagaac agccaagcaa aaatagatcc
    37741 tcatattttt cgtttggttg gtcttattac cgcagatgca agcttttgaa caccgtttat
    37801 tgagaggttg tgaaatcagc gttctgacct gagtattaga gagacaaatg gcaaaatagt
    37861 tcctcatatt ttgccatttt ttgagctaat accgagggtc agctgattga acaccgttta
    37921 gtggagaggt cgtgaaaaag ctgtttagtt tcgagtatta agaaaaattt tgtgaaaatg
    37981 gctttccaca tttttgcata aatttggctt aataccgaga aactggcttt tgaactccgt
    38041 ttatcgagag gtcatgaaaa agctgccttg cctcaagtaa taagaacagc ccaaaattag
    38101 atttctagac aattttttat aagttatttc attacattgg ctttttcttt tatgattctc
    38161 cactgttttc tcggtactct ttaggggatc tgccgacgat tttcttgaat aatttagaga
    38221 aatacgtggt gttgttgtag ccaatctcac ttgctatctc attgatgttt tgattactgt
    38281 gcaaaagcag ttgtttcgct ttttccatac gtaaatggtt caaataagct gaaaaacttt
    38341 ttttcgtttc ttttttgaac agctgtccta gatacatgac atttaaatgc aggttttctg
    38401 acacttcttt gagtgtaagt ggttcttgat aatgctggtg caggattacg attacttttt
    38461 ccacattgtc actgtacttt ttctgtctct gatgcttttt gatgaatgac agaagtagct
    38521 gctgaagttc ttgcaccgtt tttgcctgat ggattttttc gattccttgt aaatattcct
    38581 catcttccag atcaatcaat tcccgttgaa tctccataaa cagtaaaaaa ctggaatatc
    38641 gtatatcttc cggcatcatg gctgctaact gaaactgttc aaaaaaatca gtgatcattt
    38701 tttgagcgac ttccaattgt ttattttgca gcacgcgtct gaaacttgaa aaatcgatgg
    38761 tttgatcttt tgtttctgct tgtactgcgt aaaaaacatg ctcgtcttta tctccataaa
    38821 attgatgcaa ctgtagattg tctttcgctt gttggaatgt ttcagggatt ttgtccaaag
    38881 aatctgtctc ttccccgata ctgatcagcc attcctgatc aggaaagttt tcttgaacaa
    38941 aacaacagaa gccatcaact tcatctgcct ccaacaacaa cgtgatcaat acacggtctc
    39001 cgtaatttcg ttgatagtaa aagatttgtt gccgttcttg caaccatcta ttgataagag
    39061 tatcatgagt tcttgccagt tgaatcaata ctatcctatg ctgcttctca cttatttgtc
    39121 ctattatttc ttcttcactt atttcatcca attcttcatt caaccattga ctgaataaca
    39181 gttcttgata gatttcttgt tgattttttt gttcattttg ctgatctaac cgtgttttga
    39241 ttttcttgag gctttcaacc aattcgaact tattcacggg tttcatcaaa taattcacgg
    39301 cgcctaattg catacctcct ttcaaataat cgaattcttg gtatcctgat aaaatcataa
    39361 attcaaaatt atgacgttct ttttgagccg cttcaataaa ttccagtcca tttatttctg
    39421 gcattgtcac atccgttact actaaatcaa tctgtcgctg ttcaagtaca gctagtcctt
    39481 ctttggcatt ctctgctgtt gctactattt gaaagcctaa actttgccaa tcaattatct
    39541 tttttaaccc attcaaaatc atgtattcat catctaccaa taacacttga tacacgctca
    39601 tccctccttg aatgtaatag aaacggtcag tccacctgtc tcattattct caagcgacat
    39661 ataataactg ctgccgaagc tggcacgtaa acgttcattc acgttttgca gaccgataga
    39721 accgtgaagt tccactttag gatgagacag tttttcttca atctgtttta gccgtttttc
    39781 agtcatccct tttccattat ctttgatgat gatccttacc cgtttgcctt cctgcaagac
    39841 tttgacactt agcgcattat cgaatcgagt aaaatcaata ccgtgtttaa aataattttc
    39901 aactaatggc tggatcacaa atttaggtac ttcgatcttt tccaaatcag gatcgatcat
    39961 aaaatgatag gctactcgat taggataacg catttgatac aaatagacat atttttcgca
    40021 aaagtccagt tcttctttta aagtgatcgt tttctcttga ttcgtattgt ttcgaagcaa
    40081 agcggaaaac gcatacacaa catctgctaa ttcttcactt ccttcgctga ttgcatacat
    40141 tcggatatat tctaatgtat tatataaaaa gtgtggattg atctgtgctt gaagcgcccg
    40201 catatgtgcg tcttgctgtt tgatttctaa tttgtagatg tcttctacaa actgattgat
    40261 gctatccaac atttcgttga taccgattga aagttccttc agttcatatt ccgtgtttgt
    40321 tatgtcgatc cgcgtctcta aattccctgc tgctgtttga tccatggcct gcatgacgat
    40381 agatacttgc tgtgaatatc gtttgaatgt tttataaaga aagataagca gtatattgtc
    40441 taaaataatg ataccaatga tcagcggggc aagatttttt cccgtttcga tttttacact
    40501 ttttttatct agtacagcta atatacgata atcatcagac agttcttggt gttgaacaaa
    40561 attgtttttt tccagatcgt caatcggcaa ttgtgaattt ttcttcagac tctctgtgat
    40621 gatcatttct tgtctttcaa acgtttcttt agctatttta ttatcatgga atgtgtatag
    40681 tcgatttgtc gttccagaaa tcatgtataa agagagtcca ttgaatgacg ttagattttc
    40741 taaaatcata tctagttctt tcttttgaaa accaataaaa atacttcctg actcagctcc
    40801 tccttgtgtg ataggcaact tgatataaaa ggcgtctagt aattttggtg tccccttttt
    40861 tatttcccca cctttgtttt ctctagaaga ttcataatac tccggtagtt gattcaacac
    40921 gatatatatc gcacttagtt cttcataatt tgcgtagaga tctttgattt gatttgggaa
    40981 agaaactaat tcatcggtac tgttttgctg ttcgtataca tacatcagat actgatctat
    41041 gggttttgtt aagtaggtcg tcacattttc gatcttttcg gaattcccta caagctggtt
    41101 tttgatgatc ctactcaagg ttgttttatc attcagcatt ctgcttgtgc tttgaacggc
    41161 atcacttgtc atgttttctg cctgtttttg attttgttcc caagtatgga tactaaaaat
    41221 aacggtagca gtcatcgtta caccgatcat gataaccgcg tatttccgca acagacgatt
    41281 tagtaaggtt ccttttgaaa atagaatccg aaacttattc ataactttcc aactgtttat
    41341 ctaattcttc acgccaatgt gttgtcatcg taccattcca aaccgtcaaa agaccaatga
    41401 caccaaacag gatcaatcct ttgaattgcc aagtcacgcc taaaattata ccgctaccaa
    41461 taattatttt tagaaaagac gaaaagctgg aaaaaaccga aataaaactt agctttagca
    41521 gattaggaac agagatcgta tattcactat ctaaaatcat actgtattga taagtagcaa
    41581 ataggcagag caaggcaaaa agtaaaataa aatcaatagc taaaaaaatg agccctttga
    41641 tttgaacaga taaatataaa ttgtaactca ataaagcagt accagataaa aataaactaa
    41701 atagcagatt gcctcttaaa aaatttcttt tatatatatt ccagcctctt tttattgtga
    41761 tttctttata ctcgaatccg tacaaataaa atagttcatt gactgttttc catgccgcac
    41821 ctaatccaaa gatgatcccg ccggcaaatg tatatatcca gaaatacaag gttagtttta
    41881 taatgaccca gatccggata aataactctt ccaaaacctt ccctaacata tcttctcctc
    41941 caaacattaa gtttatactt tctcattata caaaaaaagg ttgggcaatc agcaccttga
    42001 cctgattatt agagaaacaa acggaaaaat agttcctcat attttgtcgt tttgtgagcg
    42061 aataccgagg gttagctgat tgaacaccgt ttaccaagag tttgtgaaat agccgcttag
    42121 tttcgagtag taagaaaaat tttgtgaata tggctttcca catttttaca tatatttagc
    42181 ttaataccga gaaactggct tttgaacacc gtttattcgg aacaagaggt tgtgacacgt
    42241 cttttgtcac aacccctttg tctttattca ttattattct tgtcggaact catcatattg
    42301 tttttgcatt tctttcaata ccttatcata gccagccttg tccaaagcgt ctttcaattt
    42361 cggtaatgtt tcatctggat caacagtccc tgtattcaat ccatctaaat attgattcat
    42421 gacattagaa atattactta attctgtttt gacactgtca gtgttgaagc tgaatcctaa
    42481 aatcggtgaa gtttctgcat cagcaatcga ttgatcacgt ttggcaatca tgtcatccgt
    42541 aatagactct tgtgtatata gaatcttgtt gtttcctgta ttccaagcag acatatgtgt
    42601 atttggctga taaccatcta gcaatttgat tttatcatct gaaccatcga ctttttccca
    42661 tgcttctccc tcgatccccc aaacaagccc attcaataat tctggatcac tgttaagcag
    42721 ccctagaagt tctactgatt tttctttatt ttttgaagta tttgatacga caaaatttgc
    42781 catttgtgct tgagctgtag attttagtgg aacagtaatt gcttttgaga caagttcttg
    42841 ttttgctgca tttgtcaaaa ttgtatcgcc ataatcatac ggtccttgtg tttctccacg
    42901 cattagccaa gtatttcctt ctagtggata atccttattg ctcgttgcag cgtcacttgg
    42961 aatgagtcct tgtttgtacc agctatgcat tgtacgtaac agtccgatat acgtttcatt
    43021 atcgtattgg ttgatgattt tcgaatcatc tccatccaga tcaatagcaa atggtaacgt
    43081 attccctaaa ggataatcaa agttcccttg gactttgaag ccttgtccaa tggcaaaagc
    43141 tgccgtgttt ggttcttttt catggaattc cttcaagact ttttctgcat cagcgtaaga
    43201 ttggattcca tcaattgaaa gatcgtattt atctagtaaa gctttgttaa aagtaagtac
    43261 ttgttgagca aagacatttc cattgactgg gaaagcatat aattttccat tgaccagatt
    43321 tcctttaata tatgcttcat ctaaatcatt ataagctttt tcagcgtact taggcgctaa
    43381 ttcagtcaaa tcagcaaagg ctcctttttg ggcattggaa acatagttgt tcgcaaaggc
    43441 gatatcataa ttttccccgg aagaaatgat gacgttcatt ttcttttcgt aatcgcccca
    43501 gccaatgtaa ttgatattga cttttacacc gatctctttt tcgattcgtt tgtttgctac
    43561 ttccatcaat tgatcgaaat tatctggttt atctccgatt tgatacatct gcaaagtgtc
    43621 cgaattgcta gcttctgcct ggtctttaga accagaacct ccgcatgctg ctaatgttcc
    43681 caacaacaac gctgaaacac ctgtaaaggc tagtttcttc cataacttca tttttcttcc
    43741 tcctaatttt atgatttata tttttgtttc tttattcttt tactccgccg attgttagac
    43801 ctttgacaaa atgcttctgg aaaaatggat agctgatcgc aataggcaac gtcgagatga
    43861 ctacgatcgc cattctggca gattctcctg gaactgaggc taatccgcct gtcaattggc
    43921 ttcctgctcc tgaattttgt gtcagatatt gaatattact ttggattttc atcaaaagat
    43981 actgtagtgg aactagctta tcatcttgga tgtatagtaa agcattgaac cagtcattcc
    44041 agtaacccaa tgcggcaaat aaactgattg tcgcaatacc tggaacagct aacggtaaaa
    44101 cgatctgaac aaatattcgc agttcgctag ctccatcgat ccgtgccgat tcaataatcg
    44161 aatcagagac cgaacgttta aagaatgtgc gcatcacaat aatattgaag ggactgacag
    44221 ccattggcaa gatcaatgcc caaatcgtat cttttaactg aagaagattt gtcataacaa
    44281 gataattggc caccatccct ggtgagaaca acatcgtaat caaacaaaaa acggtaaaaa
    44341 aacgacggaa tggaaagttt gaccgtgaaa tcgcataagc atataaagaa gtagccgtgc
    44401 tattgatcag tgtacctaaa acagtaacaa gtacagtgac gaaaagcgct tggaaaattt
    44461 tatcctgcat ctggtcgaac aagtacgtat aaccaaatat actgaacttt tctggccaaa
    44521 aactgtaccc gtgagtcgac aatatggact catcggtaaa agagatggcg ataacaaata
    44581 taaatggcaa aatacaggaa atagcaaaga gtgcaatcat tatattagag aaaaaattag
    44641 ccgtcttatt gaaagagcgg acttggactc tctccacttt cttttttttc atttttttcc
    44701 tccttagaat aatgcagaat cgctatcaaa acgtcgggcg atcgtatttg tgatcatcaa
    44761 caagacaaag ccgacaactg attggtaaag tcctgcagca gccgtcatac caaaatctcc
    44821 tgtggatgtc aggccattgt agatatacgt atccaaaact tgagtcacat catataatgc
    44881 accggaattc ctaggaatgt tataaaacag gccaaaatca gctcggaaaa tgtttcctac
    44941 ggctaaaatc gttaaaatcg tcattagtgg aataagttgt ggtatcgtca catgtttgat
    45001 ctgctgccat ttgctagctc catcaaccat agcagcttca taataagtcg gatcgattcc
    45061 cataacagat gcaaagtaaa taatgctgtt ataaccaatc cctttccatg taccaatgaa
    45121 caccaagata aacggccaat atttcggttc attataccaa ttgacagctt ctcctccatg
    45181 tccagtgatc cactgattga atattccttt gtcaggactt aaaaaagcgt aaacaaagta
    45241 actgataatg acccaagata gaaaataagg tagtaaggac atcgtttgat aaactttaac
    45301 gagtcgttta tttctcaact cgctcataat gattgcaaat acgactgaga tcagcagatt
    45361 caaaaggata aatgctacat tatataaaat tgtattttta gtgatgagaa atgcttgatc
    45421 cgaagaaaat aaaaatttga aattttccca acccacccaa ggactttccc tcaagctagc
    45481 caagaaccca tctgctgaaa tatgaaaatt tttgaatgct acgacattcg ccattacagg
    45541 tatgtaaaag aaaaaaatca tccaaagcat acccggtaca gccatcagga caagtgcttt
    45601 ataacgccat agattcataa aaaaatgatt gaaccccttt cgttttttca tctaaaaacc
    45661 cctttcgatt cattcgcaac gtaattatag cgctttcaat aatgagaata aataaacaaa
    45721 gtatagggaa aatgaaacaa agtataggag aggttgtgaa atcagcgttt tggcctgagt
    45781 attagagaaa aaaacgggaa aatagttcct catattttgc cgttttttga gctaataccg
    45841 agggtcagct gattgaacac cgtttatcag aggttgtgaa ttcagcgttt tggcctgagt
    45901 attagggaga tcgtgtcctt actatctaac tctgagtcac aaggaacaat ggggactgta
    45961 acaaaagtct tgtcacagtc ccttattccg aacaaacggt gttccagaag tagcttctac
    46021 ggaaataagc cgaaatttca caaaaaagcc atccgaaagt cagacggaca agtctgcttt
    46081 tcagatggcg ctacaactac tctgcttatt cttttagcta tccattcaat tatttttctc
    46141 tcacttgttc tagctcttct ttggtcatgg gtcgatattg ccctttattc aaatctttag
    46201 gcagccaaaa ttttcccata cggattcttt ttaaatataa gacttctttt cctactgctt
    46261 tgaccattcg cttaacttgg tgaaactttc cttcatgcaa aatcagacgg ataattgaag
    46321 tttctgtctc ttgatctact tgatcaattt ggagttttgc cggcaatgtc tgctcatcgc
    46381 catcaataat cagtccttct gcaaataaac ggatatcttc ttctgtcatt ataccgctaa
    46441 cctcagctag atattctttc tccacatgtt ttttaggtga tagtaactga tgggcaaaca
    46501 ccccgtcatt cgttaaaatc aagaggccct ctgtgtcttt atctaatcgg ccgactggaa
    46561 aaagatcttc ccgataatcc tggtcttcca ataaatcgat tacggtttga tcatgattat
    46621 cctgagtagc agaaatgact cctgcaggtt tatgcaaaat gtagtaaaaa tctttttgat
    46681 acgtaatgat ttctcctaaa taagtaaccg catcttcgaa ttcatttact tgcgctttat
    46741 cgcttttcac cacttgtcca ttgacttcga tcgttccttt tttgattaat cctttgactt
    46801 ctttgcggct gccaagtccc atatctgcta aaaacttatc taaacgcatg cgtttccccc
    46861 atttcaaaag agcatcaatc tagctcttct gattcactta ttttattttt aatttatgtc
    46921 gtaaacgcgc tattcctggt cctagtagtc tttctgccaa gcggattttc aaagctaaat
    46981 aaccatacac taaagcccct atacctgcta ctacaagaat caacaataga gactggaatt
    47041 tgctatcttc gtttaaaaaa gcaccaaaaa tcatctttgt gatccacgaa gccaaaagca
    47101 taatcaaggt aagaataaag atcagcaatg tcctgcgcca gacaaaactt ggtttaaagc
    47161 gggctacttc atggattctc tttaagatca aggtacaaga cacagcaaat ccgatcattg
    47221 tcgccaataa agggccgtat acttcaaata aacgaatggc tgggtattga agaaggagtt
    47281 tcactagaaa cccaataacc aaataattaa ttgccgcctt gttttcaaac attccttgca
    47341 gcatgttgga aactagcata tatagtccta ggaagagtcc tacaaaactt gcttggatca
    47401 gtacattact tcctagagaa tccggtgtat aaaataatgt atttagcgga taggcaagta
    47461 acataacacc aaatgtcgcc ggaaacataa aaaatgaaaa caactgtaaa tttccgcttg
    47521 tcaattttgc cagacctact cgatctttca acgtaacagc ttctgtaatc aacggtaacc
    47581 cagtagacgc gatcgatgtt gccaatgcaa taactaccat cgtcaactta tctggattgg
    47641 cactaaaaat cgaaaaaaga tccagtaact gtgcattgga atactcggtg gatgcagaca
    47701 tgatcttcat aaaagtgaac tgatcgacta atttgaagat cgttacccct gaacccacaa
    47761 taataaacgg aatcgcttct ttaacggtat ctaacaacaa ttccttcgtt gcaatattta
    47821 ttttgttttc gctgtagtga ataaacgccg atgtatacgc ttgatgtttc ttcaaaaaat
    47881 acaaaaggac aagaatactt gctagcatac cgataaatgc cgcgaaagtt gattgcgtga
    47941 ccgccgtcac atagtcacca tccatgactt tcatgatgat gaatgtagcc aatagcatat
    48001 aaaaaatacg tgccacctgt tctacaatct gcgacagcgc ataaggcatc atttcttgat
    48061 tgccttgcaa ataccctcgt atcacactca tacaaggaaa aaccaataca gcgatactca
    48121 aagaacgcat cgttggaatc agttcttctc cgccaccaga agcatgagct agccaaggag
    48181 aggcgatgta catgaacaaa gcaaacaaca ggcctaaccc gcccatcatc tgtaatgcac
    48241 ggataaataa tcgtcgtgaa gtgccatatt cattcaatga attatagcgt gcagtttgtt
    48301 ttgcaatcgc agcaggtatt cctgctgtag agatcagtag aaacaatgca tatatattgt
    48361 atcccatatt gaataatcca ttggcagcct tagcattttc gcccatccaa gcataccagg
    48421 gaatgatata gacagcgcct agcaatcttg aaatgatatt actggcggtc atccaagcag
    48481 agcctcgtgc cattttttct tgcggtgtta attgatctaa tgatggtttt ctttgattat
    48541 ccatcggtca gattccaact ttctacaaaa cattactatc attttaattg gtaaaacaga
    48601 aactggcaat cgattttata taacttttat aagaacaatt gtttttttga attcggtttc
    48661 gtttttttgg taaagtaaag aaatatacag ccttttatgg ctaacattta taggagatat
    48721 caatgacaca agaaataaaa aaactacccg ttatattttt aggtcttttc tttatcacag
    48781 ttggattgaa ttggttcttg ctccctcacg atatagcttc cgccggagtg ggcgccatcg
    48841 gacatttagt tgaaacggcc ttttctatcc aacgctcagt tactgtttgg agcatcaatc
    48901 ttatgatgct gcttctagcc gctgtcctat taggaaaatc agtatttttt aagactgtag
    48961 cgggaagtct gctttttcct gttgttttag agattgttcc aaaagtggaa atgatctcct
    49021 cacatttctt ttcactgatt tcaggaagtc ttttgttcag tcttggggtt tacacattgt
    49081 acacagtcgg ggcctcaaat ggcggtataa cgataccgcc gattattttc cacaaatttt
    49141 ttcggcttcc aatgccgcaa ggacttttac ttaccaatag tcttatcgtc tttttgaatt
    49201 attatgtttt tggattgttg gagacactat tcgttctcct atctattaca gtcagttcat
    49261 tgtttatgaa aatactcatc cgcttgtccc ctgtgtcaag aaaatttgaa taaagctgga
    49321 ttttgtcata gcggaaacaa acgatatatt aaaaagagtg tgctataata aaccaagaaa
    49381 ttgaataaag cgagggatca atcaatgagc ttctctttag aagacatccg tcatttacta
    49441 ttaaaagaaa atctattaaa agaatttgtt tcaacaagag gctggcatct tgatgtacca
    49501 gaaaaagctg aatttcttca gttaagttat gattcaagaa aagctgatgc ttctactttg
    49561 tttttctgta aaggaatgaa tttcaaagaa gaatatttgg attcagcaat cgaacagggt
    49621 attcaatatt atgtatcaga acaaccatac gaaaattcag cagtaggaat catcgtaacg
    49681 gatatccgta aagcaatggc gcttcttgct atggcttttt acgactatcc gcaaaataaa
    49741 ttgaaagtga tcggattcac tggaacaaaa ggtaaaacaa ctgctgcgta ctttacaaaa
    49801 gcaatcttgg atcacacaac aaataaaaaa acagcattgc tttctactat gaatacaacg
    49861 ttagatggca aaacatattt caaatcccat ttgacaacgc ctgagtcatt agatttatat
    49921 cgtatgatgt cagaagcagt tgaaaatggt atgactcatc tagtgatgga agtttcttca
    49981 caagcttaca aaacacaacg cgtatacggc ttgactttag atgtcggaat cttcttgaat
    50041 atctcgcctg accatatcag tccgatcgaa catccgacat ttgatgacta tttctattgc
    50101 aagcgacaat tgatcttgaa ttcaaaaaca gttgttttaa atcatgaaag tgactatttt
    50161 gatttactta gggaaacagc cgatctattc cagattccaa cgatcactta tggtcgttcg
    50221 gaagaaagca attatcaagt gatccgttca gataaaggta ctcacggttt tactttatct
    50281 tctcatgaag atcgcttagc tatctgcgat actgcttatg atattttgct ggctggagga
    50341 ttcaaccaag aaaatgcagc cagtgcgatc attgccgcag cactaacagg tgcctccagt
    50401 caagatgcac aagacggatt aaaagaagct cgtgtaccag gccgaatgga tcaattgatc
    50461 caatccaatg gagcgcatgt ctatgtggac tatgcacata attatctaag cttgaaaaca
    50521 ttgctgaaat ttgccaaaaa tgaacatcca gatggccgtg taattgttgt attaggcagc
    50581 ccaggaaaca aagcaatctc ccgtcgacat gattttggaa aagtgctatc agaaacagct
    50641 gacatcgcct ttttgacggc agatgaccca gcatttgaag atccgaaaaa aatcgcggaa
    50701 gaaatcaatg aagcaattac taatccagat ttgatcgttc attatgaaat ggatcgtcct
    50761 gaagcgattc gacgcgcttt agcagaaagc gctccgcaag attcagtcgt tattgcggga
    50821 aaaggcgtgg atccctatca aaaaatcaat ggtgtagatg aaccttatga aggggattat
    50881 gcaatcgtga agcggttgat tgaagaataa tggtatttat atactagtgg tttcccattt
    50941 ctaagaaaaa aagggactgt gattttttgt cacagttcct tttttcttag aaatcatttt
    51001 aacttttcac tagctaattc tgctgccttt tctctttctt catttaataa tttattatca
    51061 tagaatttga taaatgggaa ccagataatg aatgcgatga ttgcacaaat gactgctaac
    51121 acagcagctt tccaatcacc accactacca acaaatgctc cgatcccgac tggtgaaggc
    51181 cacggcatct gtgcaagcat cggtttgacg atttccagcc gaatggcaaa ataagcgagt
    51241 gtagcagaag ccatcggagc taagaaaaac ggaaccgcta aatagggatt gtagacgatt
    51301 ggcatcccga aaatgattgg ttcattgata ttgaataatc ctggtacaag tgaggctttt
    51361 cctaacactt tcagctgatc agatttcgcg aggaatgcaa taaagatgat caatcctaaa
    51421 gtcgcacctg atccaccaac ggttacataa gaattgttga attctcctgc caacggataa
    51481 tttgcgcctt gtgcgttagc tgccatatta gctaatacga tcggggtcaa gaaagaagtg
    51541 atgatattcg ctccatggat ccctacgatc cacaatgcat ggatcaagaa ataaatcacc
    51601 atgacaccaa gccatgtatt cgtcaactgc gtaacaaacc caaatgggat agcaatcatt
    51661 ttgaagatat ccgttcctag tgcaactaat aatccattga tgatcatcac cacaaacgca
    51721 atgacaaatg ttgggatcag agcagtgaaa gaacgagaaa ctcctggcgg aacaacatct
    51781 ggcattttta tgacccaatt tctcttgaca cacatacaat acaattcgac cgcaataatc
    51841 gacataataa tagctgtaaa gattcctgaa gttcctaaac gttcgacaaa agagcccatc
    51901 ctaataccat ttactacagt ttctgtctca ttgatagaag caatcaagct gattttacca
    51961 tcagtcatga tcaattcagg gatacacata aagaatgcaa aaacagatag taatgccccc
    52021 gtgagcggat taacatttaa tttttgttca tctcgttcaa ttgacgttaa ttcataagca
    52081 aacacaatgg caaagtaaat agataaaatc cccatcgtca ttgtattgac gatcatgtac
    52141 aagtcactaa ctttgaaaaa agttgcatta aaaaatcctt ctaaaaatgg gaacggtaat
    52201 ggcaaaatat ttaaaaccaa aaacatcgag cctacaatcg tgaaaggaat agaagccatc
    52261 cccgctgcca tgacagcccg aacgatttta agttgcgcaa ttttccccat aggtcccatc
    52321 aggtatttct gcaaaaaatc aaacattagt tattctcctt tcctaaatat aacgcttttt
    52381 catattgttt aatacggata tactgttggt cttggttgag tgaaattttc tttaaacgat
    52441 actgtataaa tgcactggca aaaataccgc ttacaacaag aatgaaaaca aataactgtc
    52501 ctccattgtt atttgccata aaaggataca agaatgtaaa tcctgaggta aacaacactg
    52561 gaatcactaa taaattaaag acactctgga acaaaaaata ccactttgtc catggaacgt
    52621 tcgtttggtg ttttcgataa agctttactt gttctcctac tgcaggcaaa atagctaaaa
    52681 tcagaatcat cggtaaacta cttcctaaac ttttagctga tagaagcaga atcatccatt
    52741 gcatgttcat gaaaaagaaa aaggcagtca ggtaacgtac gattagataa cgattgaaat
    52801 acatgttttt caaactaagt tgcttttttt ctaattcgat tttccttttt actgtatcct
    52861 gcacaatgat ccttcctttc tatttatttt tttgatacaa ataattcatt tcctgtgcaa
    52921 cttccaataa tgtcatcgtc gtcatcagat gatcttgtgc atggaccatg ataatttcca
    52981 tttctatttt tgtcccgctg gcatattctt tcagaagttg agtttgtgac tgatgcgcat
    53041 gaagaatctc ttcatttgct tgtcgcaact tctcttctac ttcttcaaac atctctttac
    53101 gcatcgagcg aaatgcttca tgtatcagtg tccgtgcatt tccgctatgg aaaatgatat
    53161 caaaagaagt cacttgtagt gtttcactgt ttattttttc agccatctgt tttcctcctt
    53221 attcgatcag tttgataaat ttactgctga aattctcaaa aataggttca gctaagattt
    53281 cctgctgtac ttttagctgg tcaactaacc taacgattgc tttagtcacg accgtaattc
    53341 cttcattttc gacataagaa ggcgaaacta aaaaaacaaa atgaatttct tgatattgat
    53401 cccactgcat cccagaagga atcaatgcaa cggctacctt tgtttcgatt ccaactggaa
    53461 cagcgggatg tgggactgcc actgtatcac tgaatatgat ttgtcccata ttttcacgtt
    53521 gctggatctg ctttcgcatt tctcttatat atccttcttc ttcatttatg ctcagctttt
    53581 gcagcaaatc atgaagaatt tcttcctttt tcggttcgta cgtataagtc ttgaaaaatt
    53641 tttcagacaa ctgttcggtg taaatctgct ttttttgctg tagagaaaat gctggtatcg
    53701 gtctatctga ggaatgatag ggtatagatt ctccaactac ctttcgtatt ttacgaacat
    53761 catcttcatt caaaaaaata ctgacatgta aaactggaat tttgaaaaac attgtcgaaa
    53821 gatcaataga agaaataatc aggtcgattc cttttaaagt tgtttcattg atctcataat
    53881 agccttttac acttaccact gtaatatttt taccgaattc actgactacg cgattcttta
    53941 atagttgggc actgccgtaa cccgttgcac agataatcaa tgcatgtagt ttatgcgcag
    54001 ctctttcttt ttccaatgcc gccatgagat gcaaagccaa ataggcccat tcatcttcat
    54061 tgatggtata gtttttcaaa gccggcatgt tgctgaaatg cctttttact gcgtcaaaga
    54121 ctttgggatt ttctttcttt atctcctcag tcaatgggtt ctcaatgcga atacctcggc
    54181 tcaatcgaat catcatcggt gacaaatgat cgagtagtcc attgaaaagc tggagatcct
    54241 ctactaatga aaaatgaaat tcctgagaca atcttttcag aactttcgct aattcctttg
    54301 atagttcctg atcattttga ttttctttgt gattcgactt agccatgaga tgtaatgtca
    54361 aataagcaat ttcttcttcg ggaaacgata cacctgcgat tacctcaata cgttgaacga
    54421 tccgctgcgc cacttgatac tctactcgct tagaaacttc ttgttcgatg cctaattcct
    54481 tgatttcaaa cccttctcgg agccgtttga tccccaaagc caagtgtaaa gtcagattct
    54541 gtatgataaa atccgaaact tttaacttag cttctcttgt ttcatcgaga atgataatga
    54601 ctagctcttc aaaactgatg tctgggaaaa aacggctttg ccctaaatat tctttcaatg
    54661 aatttccata atggtttcca aaaaaagtat ccatgataaa atgccgtcga tttctttctt
    54721 ccccttcgat ccatgtccct tgaccatgct tagaaacgat ttttagtgaa tatggaatca
    54781 atcgctcctt gatttcttgc atgtcctttg tcaaactgga acgactgata taaagctctt
    54841 ctgccaaatc atccataaaa agaatggcat cttccaaaag caattggttc aatatatact
    54901 tttgtcgatc ttcggactca taaaatcctt gcggttctct agcatatcca ggtactattt
    54961 cttgccgact caaaaacaag tcaaatgtca gtctttgtaa aatatgcagt tggtagccat
    55021 aacctggttt agcaatgatc ttacctccgt ttttttctac taactctttg atccgctgca
    55081 agtaattacg gattgtccga tcagataata acaattcaga agctaaacgt tgactggtga
    55141 catactcctt cttgtgatca atcaaatatc tcaacagcaa tttttccttc tgtttcatta
    55201 tcatccactc ctattccatc atatgttctc ttcgatcacc tctgctaact tctggatgcc
    55261 tgtagggatt gggacatacg cttggaaagg gatactaaca acaggctttc caacagattc
    55321 tcctaatttt ttgaatttat ccaaaaacat cgtcgtttgc gggctgatca gaaataaatc
    55381 aaaatcacta ttcttaatca tattatcgcc ttctgtagct gaaactgcat ctacgagtac
    55441 ctcttctctt ttttgcttaa agaaatccgt tgtctttgag gccatcatcg aggatgacat
    55501 tcctgccgca caaataatca atgctttttt cataaatcaa tcactccttt tatttttata
    55561 aaccaagcat atcttgtaag cgttttctat tcaaaatata tatttccgta gcattgcgga
    55621 aaaaatgtgt atcatatctt gaataataat ttctggcacc gtgatatact agtgatagaa
    55681 ttttttcagg aggggattta gtgagtatca cagtgaatat tttgtataca agtacaaatg
    55741 gacaagccag aaaatttgca gaagaaatgg tcgaaagaaa cattgtcaaa gcgattcgtg
    55801 cagaagaagg aaacgagaaa tatgactatt actttccact agaagatcca gaatctcttt
    55861 tactgatcga ccgttggaaa gatgaagaag caatcgaaaa gcatcacaaa tccgaaatga
    55921 tggctcaaat aaacgaactc cgtaaaaagt ataaattaaa aatgaaagtc gaacgtttca
    55981 ctgatttacc gtaaaaagat acacatggaa tgatagcaat ttatcatcca tgtgtatctt
    56041 cactttttcc ttatttttta ttcgatctca tctaatgatt caaaccgtgt ttttctctta
    56101 tttttcggat aagtatttca gtcaccccaa tatacatgat tcctaaacat accccaagga
    56161 tattctcaaa aatgcggatc gttactgctc ctggaacccc gaataaactg gcagtgattg
    56221 ccaaagcacc aaaagaatta aaaactgttt tatatctata ggtagaacaa acacctaaag
    56281 ctagaccacc taatataccg acccagttaa aaggaataaa ttggctgata ccaataaata
    56341 aaacacatcc aatcaatgag ccaatgattc ggtctactgc tcgttctttg aaaccaatcg
    56401 acatcaatcc atagctagat acaatagaag aaaatgcaaa ccctgcccac atcaatcgct
    56461 gaaaagggac atactctcct gcaacgatca aaagactaat gccaaatgca tagatgagca
    56521 tccaaatttt ttcctgcgaa tacatgcctt tcaaaaaaat ctctttaaac aagcttttgt
    56581 ctttgttctt ttctcgatgt tttctgtaaa ggagaactga aaaccaacaa aaaaacaaaa
    56641 ataataagct acttgtttgt gtaaagaaat tcttgttcaa cgaatcttta ggtaacgaat
    56701 aaacaataaa gagatatgaa aagccgtaca aagaagcatt ccccattttg ggatcactag
    56761 cggttgccat taatatgctg cttagtaaaa taaaatgaat caacatgccc ataactgacc
    56821 atttgatcag ctggacatac ggtgctacta atagtgagaa catgacgatt gctaaaccta
    56881 tgatcgaatg ggaaatctta taaccaaagt caacaaaacg aatactcatc aacatacaga
    56941 ataaaaccac agcgtatggt ttatgcttcg attcaaataa tgttgtaatt ataatgataa
    57001 aacaaatggc aaacaatacg atgaataatg atcgtaaaaa caatgaacaa atatacatgc
    57061 acttttcttt tttagaagct gcttctcgta ttttttgttt taaaataaac ggatctagtt
    57121 gtagagactg ataaaaatcc acctgttgtc gtcctttctt tttactttta ttttttacag
    57181 tcatctatga caggttgtaa atactatgga acatcatatg gcgttgtcat tttcttgtca
    57241 actatttttc ctattcatgt ttttataaaa aaacatatcg ttttcttgta tgattaaatc
    57301 accacaaaat aaacaactga gagaacgata tgctttatga atggttctat caaaaaaatt
    57361 ctgagatcaa tagacaaaaa tttgatgatt acagaggtct cttacgaaac cttacagaag
    57421 aaaaaaacat tgatcgttgc tgcagttctc ttccctgctc catgtgtctg tagaaattgt
    57481 ggttctgctg tggtagatgg aaataggaaa ttaatggtgg tgaaaaacaa gaagaaggaa
    57541 accattgtcc actttgaata atataatcat atgccaatgg ttatacgcct aaaaaagcag
    57601 cgctatacct gtaaaaactg tcgaagccat tggaacgctc aaagttattt tatccgtcca
    57661 aggcactcga tttcaaatca tgtcagacat aaaatcactt ctttactgac tgaaaaagtg
    57721 tcgttatttt ttatttcgaa aagttgttag gtatctttga caaccgttat tcgcacattg
    57781 aaagagttga gaagctattt accaaagtct tccaaaagaa ttctgtcttg agtgttgagg
    57841 gttgtgaatt tcgttctcac gtttccgttg aggataaact gagttttatt tccgcggatg
    57901 gcgagacaga aaaattaatc gagaaaattt acctacacaa aaaattcctc gattaacaaa
    57961 ctatttcctt agctgcacta atcctaaaga aatagaattc ttagttacag acatgaacgc
    58021 cacctacttt cagctcacca aacatgttct accaaatgcg aaattggtga ttgatcgatt
    58081 acttggtttt tccacgcctt tcaaggaggc gtaaccttta ttcacgagtt ggttgaagct
    58141 ttccgagaca aaagacccga cttgtttttc tccttattga caaagagcca ttaaaactag
    58201 agaaaaaatt acaactgatc gctgattatt tgtagaaaga aaatcaaagt attacccaat
    58261 aaacttgagt cattaggcaa aaaacactgc gaaactcaag aatgattttc gcagtgtttt
    58321 tgtatatttt ttattaacta gtattactac aaaggtttat ttttcacttc tcaacgcagc
    58381 acaaaattgt ctttacttat ttactggttg ggttcaacct tctctactcc gatactaata
    58441 tttgtttgta taccccttct aaaatcggta gtttccattc aattgatggg tactagttga
    58501 ttttaaaaac tatgcttatt caatttttta ttttagctca tatatttcgt ttctttctaa
    58561 attttatact gatgaaaaca agtagcacac ccaatattga caatataaac tggctaatga
    58621 tggtttctcc agtttttgga agatgcttat ttccactgct tgttggattg tttcctctta
    58681 tatctgagct atcagcaact tttctattct cttttgttaa aaagatcgcc acttcttgtt
    58741 ctttttcgat cttgaaagtt actggtgtcg catccaattc ataccccgtt ggcgcttgag
    58801 tttctaccag ctgatatgct cctggtgcta agccatctat cgccagtttt ccatctgctc
    58861 ctgtggttag acctgactgc agaacggttc cattggcatc ttgtaactca aaaacagctc
    58921 cttgcaggac ttctccgctt tggtcatcga tctttgtcaa cacgacaccg cctggtgtaa
    58981 gtcgattttc tttcgtcaat tctaccaccg ctgtctgact tctttcgatc tcaaactcga
    59041 ttggtgtcgc atccaattca taccccgttg gcgcttgggt ttctaccagc tgatacactc
    59101 ctggtgctaa gccgtcaatc gccagttttc catctgctcc tgtggttaga cctgactgca
    59161 gaacggttcc attggcatct tgtaactcaa aaacagctcc ttgcaggact tccccgcttt
    59221 ggtcatcgat ctttgtcaac acgacaccgc ctggtgtaag tcggtttgct ttcgtcaatt
    59281 ctaccaccgc tgtctgactt ctttcgatct caaactcgat cggtgtcgca tctaattcat
    59341 acccc
//
LOCUS       DAYNVV010000010        57777 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.010, whole genome shotgun sequence.
ACCESSION   DAYNVV010000010 DAYNVV010000000
VERSION     DAYNVV010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57777
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.010"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..298
                     /locus_tag="ACGXWR_000762"
     CDS             <1..298
                     /locus_tag="ACGXWR_000762"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802368.1"
                     /translation="YNTNIQQGHNNNMIVSIDDMSELLSKLDLLLENLNDSLPEEEVE
                     EAQEYIETIKDEAIKEKPKKTMLRFAVDSLKKLKWSTEFLASVATIAQLVAPLL"
     gene            complement(737..1882)
                     /locus_tag="ACGXWR_000763"
     CDS             complement(737..1882)
                     /locus_tag="ACGXWR_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFK0802369.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(1943..2590)
                     /locus_tag="ACGXWR_000764"
     CDS             complement(1943..2590)
                     /locus_tag="ACGXWR_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFK0802370.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            2784..3077
                     /locus_tag="ACGXWR_000765"
     CDS             2784..3077
                     /locus_tag="ACGXWR_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802371.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            3121..3432
                     /locus_tag="ACGXWR_000766"
     CDS             3121..3432
                     /locus_tag="ACGXWR_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802372.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            3429..4053
                     /locus_tag="ACGXWR_000767"
                     /pseudo
     CDS             3429..4053
                     /locus_tag="ACGXWR_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            4194..4352
                     /locus_tag="ACGXWR_000768"
     CDS             4194..4352
                     /locus_tag="ACGXWR_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802373.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            4353..4715
                     /locus_tag="ACGXWR_000769"
     CDS             4353..4715
                     /locus_tag="ACGXWR_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802374.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            4752..5600
                     /locus_tag="ACGXWR_000770"
     CDS             4752..5600
                     /locus_tag="ACGXWR_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HFK0802375.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            5590..7065
                     /locus_tag="ACGXWR_000771"
     CDS             5590..7065
                     /locus_tag="ACGXWR_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="HFK0802376.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            7331..7738
                     /locus_tag="ACGXWR_000772"
     CDS             7331..7738
                     /locus_tag="ACGXWR_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HFK0802377.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            7741..7956
                     /locus_tag="ACGXWR_000773"
     CDS             7741..7956
                     /locus_tag="ACGXWR_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802378.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            7960..8340
                     /locus_tag="ACGXWR_000774"
     CDS             7960..8340
                     /locus_tag="ACGXWR_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFK0802379.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            8474..8629
                     /locus_tag="ACGXWR_000775"
     CDS             8474..8629
                     /locus_tag="ACGXWR_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HFK0802380.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            8698..9171
                     /locus_tag="ACGXWR_000776"
     CDS             8698..9171
                     /locus_tag="ACGXWR_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HFK0802381.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            9168..10862
                     /locus_tag="ACGXWR_000777"
     CDS             9168..10862
                     /locus_tag="ACGXWR_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFK0802382.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            10828..11013
                     /locus_tag="ACGXWR_000778"
     CDS             10828..11013
                     /locus_tag="ACGXWR_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802383.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            11017..12192
                     /locus_tag="ACGXWR_000779"
     CDS             11017..12192
                     /locus_tag="ACGXWR_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFK0802384.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            12185..13708
                     /locus_tag="ACGXWR_000780"
     CDS             12185..13708
                     /locus_tag="ACGXWR_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFK0802385.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            13764..14048
                     /locus_tag="ACGXWR_000781"
     CDS             13764..14048
                     /locus_tag="ACGXWR_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HFK0802386.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            14035..14370
                     /locus_tag="ACGXWR_000782"
     CDS             14035..14370
                     /locus_tag="ACGXWR_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFK0802387.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            14665..15291
                     /locus_tag="ACGXWR_000783"
     CDS             14665..15291
                     /locus_tag="ACGXWR_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802388.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            16033..16869
                     /locus_tag="ACGXWR_000784"
     CDS             16033..16869
                     /locus_tag="ACGXWR_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFK0802389.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            16934..17368
                     /locus_tag="ACGXWR_000785"
     CDS             16934..17368
                     /locus_tag="ACGXWR_000785"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFK0802390.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(17436..18758)
                     /locus_tag="ACGXWR_000786"
     CDS             complement(17436..18758)
                     /locus_tag="ACGXWR_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HFK0802391.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFWDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(18912..20552)
                     /locus_tag="ACGXWR_000787"
     CDS             complement(18912..20552)
                     /locus_tag="ACGXWR_000787"
                     /EC_number="4.1.1.101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043883 - malolactic enzyme activity
                     [Evidence IEA];
                     GO_process: GO:0043464 - malolactic fermentation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malolactic enzyme"
                     /protein_id="HFK0802392.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            20882..21352
                     /locus_tag="ACGXWR_000788"
     CDS             20882..21352
                     /locus_tag="ACGXWR_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HFK0802393.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            21981..23084
                     /locus_tag="ACGXWR_000789"
     CDS             21981..23084
                     /locus_tag="ACGXWR_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HFK0802394.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            23368..24048
                     /locus_tag="ACGXWR_000790"
     CDS             23368..24048
                     /locus_tag="ACGXWR_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFK0802395.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            24138..25172
                     /locus_tag="ACGXWR_000791"
     CDS             24138..25172
                     /locus_tag="ACGXWR_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFK0802396.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            25186..25521
                     /locus_tag="ACGXWR_000792"
     CDS             25186..25521
                     /locus_tag="ACGXWR_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802397.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            25505..27985
                     /locus_tag="ACGXWR_000793"
     CDS             25505..27985
                     /locus_tag="ACGXWR_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802398.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLADIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISTSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSVQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYEAKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            28041..29600
                     /locus_tag="ACGXWR_000794"
     CDS             28041..29600
                     /locus_tag="ACGXWR_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0802399.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            29597..30961
                     /locus_tag="ACGXWR_000795"
     CDS             29597..30961
                     /locus_tag="ACGXWR_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HFK0802400.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            31132..32202
                     /locus_tag="ACGXWR_000796"
     CDS             31132..32202
                     /locus_tag="ACGXWR_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0802401.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            32217..32885
                     /locus_tag="ACGXWR_000797"
     CDS             32217..32885
                     /locus_tag="ACGXWR_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802402.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            32905..33483
                     /locus_tag="ACGXWR_000798"
     CDS             32905..33483
                     /locus_tag="ACGXWR_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFK0802403.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            33886..34797
                     /locus_tag="ACGXWR_000799"
     CDS             33886..34797
                     /locus_tag="ACGXWR_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFK0802404.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(35053..35970)
                     /gene="rnhC"
                     /locus_tag="ACGXWR_000800"
     CDS             complement(35053..35970)
                     /gene="rnhC"
                     /locus_tag="ACGXWR_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HFK0802405.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            36172..36609
                     /gene="zapA"
                     /locus_tag="ACGXWR_000801"
     CDS             36172..36609
                     /gene="zapA"
                     /locus_tag="ACGXWR_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFK0802406.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            36667..37214
                     /locus_tag="ACGXWR_000802"
                     /pseudo
     CDS             36667..37214
                     /locus_tag="ACGXWR_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
     gene            37329..39689
                     /locus_tag="ACGXWR_000803"
     CDS             37329..39689
                     /locus_tag="ACGXWR_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFK0802407.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            39776..40090
                     /gene="trxA"
                     /locus_tag="ACGXWR_000804"
     CDS             39776..40090
                     /gene="trxA"
                     /locus_tag="ACGXWR_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HFK0802408.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            40272..42050
                     /gene="uvrC"
                     /locus_tag="ACGXWR_000805"
     CDS             40272..42050
                     /gene="uvrC"
                     /locus_tag="ACGXWR_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HFK0802409.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            42195..43094
                     /locus_tag="ACGXWR_000806"
     CDS             42195..43094
                     /locus_tag="ACGXWR_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802410.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            43087..44349
                     /locus_tag="ACGXWR_000807"
     CDS             43087..44349
                     /locus_tag="ACGXWR_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0802411.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            44512..46410
                     /locus_tag="ACGXWR_000808"
     CDS             44512..46410
                     /locus_tag="ACGXWR_000808"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HFK0802412.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(46709..47428)
                     /locus_tag="ACGXWR_000809"
     CDS             complement(46709..47428)
                     /locus_tag="ACGXWR_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HFK0802413.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     misc_feature    47618..47665
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF03071"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="sodium ion sensor (DUF1646 type); this
                     cis-regulatory element may regulate processes involved in
                     with the transportation of sodium ions; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF03071"
     gene            47765..48097
                     /locus_tag="ACGXWR_000810"
     CDS             47765..48097
                     /locus_tag="ACGXWR_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802414.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            48084..50087
                     /locus_tag="ACGXWR_000811"
     CDS             48084..50087
                     /locus_tag="ACGXWR_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HFK0802415.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            50106..50576
                     /locus_tag="ACGXWR_000812"
     CDS             50106..50576
                     /locus_tag="ACGXWR_000812"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HFK0802416.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            50597..51181
                     /locus_tag="ACGXWR_000813"
     CDS             50597..51181
                     /locus_tag="ACGXWR_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HFK0802417.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            51196..52182
                     /locus_tag="ACGXWR_000814"
     CDS             51196..52182
                     /locus_tag="ACGXWR_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HFK0802418.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            52172..52483
                     /locus_tag="ACGXWR_000815"
     CDS             52172..52483
                     /locus_tag="ACGXWR_000815"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HFK0802419.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            52505..54286
                     /locus_tag="ACGXWR_000816"
     CDS             52505..54286
                     /locus_tag="ACGXWR_000816"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HFK0802420.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            54279..55655
                     /locus_tag="ACGXWR_000817"
     CDS             54279..55655
                     /locus_tag="ACGXWR_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HFK0802421.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            55662..56297
                     /locus_tag="ACGXWR_000818"
     CDS             55662..56297
                     /locus_tag="ACGXWR_000818"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HFK0802422.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            56327..57682
                     /locus_tag="ACGXWR_000819"
     CDS             56327..57682
                     /locus_tag="ACGXWR_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFK0802423.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
BASE COUNT        19274 a         9798 c        12160 g        16545 t
ORIGIN      
        1 ttacaacact aatatacagc aaggccacaa taataatatg attgtttcta ttgatgatat
       61 gtcggaatta ttatcaaagc ttgatttgct tttggagaat ttgaatgatt ccttacctga
      121 agaagaggta gaagaggctc aggagtatat cgaaaccatt aaagatgaag ctattaaaga
      181 aaagcctaaa aaaactatgc tgaggtttgc ggtagatagt ctaaaaaaac ttaaatggag
      241 tacagaattc ttagcttctg ttgcaacaat agctcaactt gttgctccac tgctataagt
      301 ggagaatgag gtgttcttca attaaccgac ttgccaagtt gtggtaatgg tttgagataa
      361 tgaaagcttt gtattctata gagattgatg tatctgaatg aatgcttgtt tttttggata
      421 tagctgatta atcagtggtg ttacattatt tataagtcgt ttgattaact agttcttacg
      481 atttcttatc aaaagcacgc cacgcaactt gaatacgttt ttgaatacga ctaaaaaacc
      541 acttaaggtg aattagactt aataaagtga ttagttctat tcaaaaatcg ttgaaatacc
      601 aactatcgtc aattatcttt aatgagctta acttcatggc ggaagaagaa gaatagacta
      661 taaagctagg agaaaccttg atatgatagg gtttctcctt tttttatttt ttactgtatg
      721 ccatattgta tgccatctag tcaatattta agtgttgtac taatttttca acagtctttt
      781 ctttcgtttc ttttgccaag tgaccgtaac aatcgatcgt ctgactaatt tttgtatgcc
      841 gtaatctagt ttgaacttct accatagtag ctccagcgtc caagagcatt gaagcatgag
      901 tgtgtcttgc tacatgcaca ccgagaaatg gaaccatagc tttttcacaa atagtaatca
      961 atcttgcata aatagcgtgg tgtgtgatta gttctttata gataccacaa aaaatcatag
     1021 tcggatcagt tacaccaagt gtcagcatat atttccgctg attaatctgc cattttttta
     1081 atatagaaat tgttctttca tctagtggaa gaaccccagc actacaatca gttttaggat
     1141 cactgatttt atagccattt ttggattggc ttagtgtttt attgatggtg accgtatttt
     1201 cttgaaaatc aatgtctgac caattcaatg caagggcttc actgatccta accccgctat
     1261 aaaagagaaa gcgtagtaac gttttatcaa agtcgtttcg ataagtttca ggtttgctgt
     1321 ttaggtaatc aaacaaggtg atcagttgtt ctttactgta aactttgacc ttttctttat
     1381 gcttagtggt ggttctttta ggcattaata cgttgtctag tggattagtc tcaataatcc
     1441 caagattgat agcgtagcta aaaatacgct tagaagttga atgaagtacc ttgtattggt
     1501 cagtagtttc agcccagcta tttacaattt gttgggcttt ttttaccgtg acttcattca
     1561 cacgaagatt tccatatttt ggaagaatcc actttctaaa cttgatttca gttttcatga
     1621 aggtggcttc tcggacagtg gttttatatg tttctagcca caagtcataa acttctttaa
     1681 acgtttcgtt gttcgctttt ttaataccgt ttttatcgta gtccacttgc aagcgtgaca
     1741 aggcaagctg ggcttctttt tttgttttgt aacctcgtct acgaacctta tcaggtttgc
     1801 cagtcatttt gttcattcca agataggctt catagagcca aaatttacct tttttagttt
     1861 catattgctt gaatgttgcc ataatagttt tccctccata gtgtagcaag ccgtgggggc
     1921 ggttggagga ggcagtttat tattattttg aatagtgttt atttagctca gtaacaagag
     1981 ctgtgaactc ttttagaaga tcattttcat aaaattcttg atactctttt ttctcatctg
     2041 tatttttttc tgaatcatta attaatgagt catatcgtaa aagcgtattt agaagagctg
     2101 cgagataagc aattggggta ctcccgtcag gaaattcaat tcgagatcct gttttaagat
     2161 attttattgc gtttgttaaa taaatcttct gtgagacagt caggttatct tcttcgatgt
     2221 tattgatagc attagaaaga ttagaatcaa ttatagagtt atttttttca atagtttttt
     2281 tcaattgctt ttcaagcaca tttcgcttaa tttcgggcat catatgcata tctcttaatg
     2341 tataagatcc gtttaataga taggtagtgg atacatctaa tacctttgaa agttgtttaa
     2401 gcctggtgtt attgggaaga ttatagccat tttcccaatt actaacggca cctttactgg
     2461 ccggtgggga taatttacct ccaagttgtt ccattgagag tcccttttca attctagcca
     2521 gtctaattct ttgtcctgtc tccactgctt cggggtattt ttttctagcc acattttcac
     2581 caccattcat atattttctc tactatatca cgatttaaat atgtgtgaaa cataaaagtt
     2641 caaaaaagta tgttaaaatt cttgcaaatg aaaaggtatg atggtatatt gagtttataa
     2701 gaggtataga aatgtattca agagcctctt gcattttttt aaaatctttg tatagaaatg
     2761 tatgctaacg aggggggata aatatggaat taaaaattga caaactcacg cttgatgatc
     2821 cagcttttaa aattattgac gatcgagttg ttcaacaagt agagcaaact caaggaacgt
     2881 tactttcatt attagaaaaa aagtaccagt ttccaaaata tatgaacaag gcacaagctg
     2941 ctaagtatat gaacgtttca tacaatacta tgatgcagaa atatgttcct aacggtttaa
     3001 agttgattat agttgatgga gtcgtaagaa tttcacaaga tgaatgtgat cgctttatgg
     3061 aagaatacca aaaataaacg caagccgtgg gggcaaaggg attaatagga ggaaataata
     3121 atggaatcga cacaaaataa agcaatcgaa aaagtattat caacaattct tacagaagac
     3181 acagcggcag aattagcaaa cttggaaggc aaagcgctag aagaaacgtt tgaatgtttg
     3241 tacgaacaaa tggactatca aaaattgcta ccacaagaac caacggtaag cggagtattg
     3301 cgtggcttga acgatttagt acaagcagag tttaaagaac gactttctat tgaagagtat
     3361 caagaaattt tgtatcagca agttgagttg ttagcgagct tgctagggct tgaactggag
     3421 gacgttgaat gaaaactgaa atttggaacg gacacattat aagatttgtc gatattaatg
     3481 atgaatggtg ggcagtggcg aaagatgttg cggaagcgtt aggtcttaaa caggttacta
     3541 gagccattca ctctttgcct aaagatgggg ttactactag taaggtcatc gattcattgg
     3601 gcagaacaca agatgtaaac atcatcaacg aaaaaaaata tttaccgcat ggcattcaaa
     3661 agccgtaaaa aagaagccga ggcatttcaa gactggattt tcgacatcat caaagaacta
     3721 cgccagtcca caggacttga aggctttcaa gtattccgca tgctagacaa agaacaccaa
     3781 aaagaagcaa tgactaaatt aagccacgct attactgaac caaaaccagt agactacatt
     3841 aaagcgaatg tgatagccaa taaagctgta tcaactattt atggtcattc caaaatggta
     3901 aaaaagaaag atatgactcc tgaaatgttg gttgatcgtg aacctatttt agatgagaca
     3961 gtagaattaa tgactgttaa agaaaaatat gggttgcagt tttcagtgag tgagaaaatt
     4021 tataatcgtt ctgctgaatt gcagacaact taggagcatt aacatgatcg agaacaaaga
     4081 aaaagcctta tccataacag tcttggcgga caggataaag gcaacttaat tgggataaaa
     4141 cccgatattc tttgttccga ttataccata ttaaaaaatc ggagggaacc attatgaaac
     4201 gaaacttaat tataggaagc attttaatcg gcggaatttt cggcttatta ccattaattg
     4261 caaaaatagc tatctttgca ggattagcgt tatatctctt cactgcttat gacgagtacg
     4321 actatcaatt aagaactgga gggcataagt agatgtacaa aacaaaacta ttaaaccaac
     4381 tcgatagcct tgaattagag gaaattaatc aagggatcgc tgaactagaa aataatatcg
     4441 ggaaaaccta ctttggaaat tcattcaatg aaaaactaac agttttgtat gtactcaaaa
     4501 aacatgcaga acacaaaata atttgtcgag aaatcaacga gctaaaaaat cagattttaa
     4561 ccgcatggtt aaacattact gatatgcaag aagcaagggt gaaaacattt aatacatggg
     4621 taaagtatca gaatcaatta aaaggtgctg aatttgttcg ggatgggttg aaatacgaac
     4681 ttgagcagtt gaagctcatg gaggtgtctg aatgatttat accagtattt tgaaaaagga
     4741 ggagaggttt attggcaaat aattatcaag cagcaacgga attacaaaag tcgggatggt
     4801 caatttatcc cttatctcct ggaactaaaa ttccaataaa aggctctagt ggttggaatg
     4861 atgcaactaa cgattctaat caaattaatg aatggtggac ggaagatgca actagaaata
     4921 ttgggttaat gcttgaagat catcaaatgg tggtagttga cctagatcaa cattctgaaa
     4981 cacgaaacgg cgttgagaat tataaaaaac ttgcttcaat gtatgatcca tttccttcta
     5041 cttatacgga aatcacacca ggtaaaggaa tccatttctt ctttaaaatt cctgatggtg
     5101 taattatcca acaagaaaca ggtgcatttg ctgatatctt cgggcgtgat gataaaggta
     5161 aaagtttaag cgggattgat attatcacta aaggagttcc aatagcgcca actatgatta
     5221 tttcaagaag tgttgggaga gcatatgaac ctattgaaaa cgtatctcta aataatattg
     5281 caccagctcc cgattggcta gtgaacctac tgctaaaaaa accgcaagaa ataaagactc
     5341 aataccgacc cgtagcaaaa acagggacag caaaaaaatt agatatgatt gttcaaggcg
     5401 ctggcgaagg tagtagaaac gatcatttaa ctaagttatg cggttggtta ctatggcacg
     5461 gtgtagataa tcaaacttta gcagaattga tttatacagc aaatgcgtac aatgaaccac
     5521 cgctaaaaga taaagaagtg aatcaaatta ttcgatcgat gattaaaaaa gatttgaggg
     5581 ggaaagctca tggctcataa gcataaatta gatagtattt tagactttcc cgaagccagc
     5641 gagcgtgaag acaatatcat tgaattgaaa acctggatgt cacgattaag atgcaataaa
     5701 gacgatcaga ttaaaagtaa cagtgttgtg aatgcagaat tgattttaac caatgatagc
     5761 aatttagctg gaacaattgc ttataacgaa tttagcggat acattcacct attaaaagat
     5821 tctccttgga tcaatcgtac cgctggagaa tgggaagaca gttttgagga tgccttaacg
     5881 gcatatattg aagaaaacta caatgtagtt tttgatgaca acaaaataca caaagcagta
     5941 gtaaatgtgg ctagaaagaa tgttttcaac ccagtaaaag aacgtatcga aaaagttaaa
     6001 tgggatcaac agcctagact ggaaacactg tttattgacc ttttaggggt agacgacaac
     6061 ctttacacac gagaagtaac aaaacgttgg atagtcggat cagtcgcacg tatctataaa
     6121 ccaggaataa agtttgagat cgttccagtt ttggatggac cgcaagggat tggtaagagt
     6181 accgttccag cattacttta cacggatgat tttttcaccg attcattaga ttcgctaggt
     6241 gaaaagaaag atgattatat gcagcttcaa ggcaatgtaa ttattgaact tggagaatta
     6301 tcttcaatga acaaaactaa aattgaacag ataaaaaact tcatcagtgc caagatcgat
     6361 aaaattagac ctccttatgg tcggaatgtc atagcttggg caaggcaatg tgtatttatt
     6421 ggaacgtcga atgatgggca gtatttgaaa gatgatacag gaaaccgccg tttttatcct
     6481 ttgccttgta agaataagcc aaagatgaat ccgtttaaaa caaaggatga atattttctt
     6541 caagtgttag ctgaagcaaa ggtgcttttt gataaaggac aacgaatcta ttttagtccc
     6601 gatgaagata aagaagtctt agaaattgca aaagactatc aagaggatgc caagatggag
     6661 aatccaatta aagaagcaat cactaaatat ttggaaatgg aaatcccgta taaatgggaa
     6721 gaagctccag cgtgggcgag acgttcttat tatcagaact atcctgacag taaatgtaat
     6781 gagaaaaatt tacagcattt ctataatgga gctactatgc aacaagagtt ttatttagtt
     6841 gatagcgtac tcaccgctga tattttggaa gctgtttttg ataaacaagc aaaggattta
     6901 ttgaatggtc gatcagatgc agaaactaaa aagattgcct tgattattag cagtattcct
     6961 ggttgggaac ggaagcaact gccaaaaaga aataaacgac gaggatttta caataagtca
     7021 aatgcctatg aaaataaaaa tcgagctgga aagtacaaaa agtaacgggt agtaacgggt
     7081 cagtaacacc tagcccgtta ctagtttacc cttactgccc caagggatac agcaatttgg
     7141 taacggggta acaccttatt tccttaaaac ttttgaaata gttagctaat atgctgggga
     7201 ataatgttac tggattttac ccgttacctg ttaccaaaac gctagaaccc ttgtccccgt
     7261 tgggattgag tggtaacggg tacctgttac gtaggtgtta ccacgtgtta cgaatcaagg
     7321 aggaaagtaa atgctcaata ttatttcaac aaacaaagca ccgaactttc aatatacaga
     7381 tgaaatggat cggtttctaa tgaacacgct ggcatttagt gtgggattgg taacagaaga
     7441 ttattccaca tttgatccag aagtattaaa gataatggaa gaagaacctg attggctgca
     7501 ggagtcagta gcgtggtgtc aatcgctagt agtgggatca ttggtagata gtggcaacta
     7561 tgatgataca ggtgagctaa tggatgaatt taattgtctg cttaacctat atgatcgagc
     7621 gagacaacga gagcttacat cgaatgagga taatttgttt ttaaacatcc atgataagtt
     7681 cttggctttg ctactaacag atgatgaatt gataactaat ttattggagg tagaataatt
     7741 atgcatatgg aaagtattag atacttcgat ggtgagaaac acattgagta ttcaaacact
     7801 caagaagatg tagactttat tagttttgag gaagataaaa tcactaaagt taattttaaa
     7861 gacggaacgt gcttgaagat agtttcgcct tatattgaat acaaatcaaa atgggaacaa
     7921 gatgattctg acgaacgaga tcgctttggt tggtaatcta tggcagttaa aaaacaatgt
     7981 aatcatgctg gatgtaaaac attgattgat tataggcaga agtattgtgg gaagcataaa
     8041 gcaaagcaaa cggcaattaa gcgtgaagaa agaaagcaaa gcgaaggtaa atattttcaa
     8101 ttctatcaaa gtagaacatg gcgaaaggct tcatacttgt atcggttaaa tcatccagta
     8161 tgtgaggatt gcctagaaga aggcttgata aggaaagctg atgttgtaga tcacaaaatt
     8221 gaactaaaag atgattggaa tagacggtta gatgaaacta attttcgttc tttatgccat
     8281 gcacaccata attccaagac agccaatgaa agacaaagac gagaaaagag taccctttga
     8341 gttaaggggg catagtgtga aacttactga caatcgatgc ctactcattt tggtacaaat
     8401 aaccgttgtg aaaaggcata agggtaatta caaataacga ttacacttgt aatcacaagt
     8461 gaaaaagtat ataatgaaag taggagattt attgaaaaat acaattgtta ttactgataa
     8521 aacagggaaa cagcgcacca ttgagttacc tcattttggt caagtgacca ttcaaatgca
     8581 gaacggaaaa atcatttata tagataaatt agataaagaa aaattctgat cgaaaaacga
     8641 aggaatgtga gcttaattgc ttacgttcct ttttcttttg tctgaaagga ggacaacatg
     8701 ggacacccta aaatattaca cgatacaaaa ggcaatatat caagtgaaga aaaagcaatc
     8761 cgtgtggacg ctagagaaga attgttcaag cagcaaccat taataaatat cacgccccct
     8821 gactggatgg cagcgagcgc tagaagtgaa tggaatcgta tcgtaccaac attaaaaaaa
     8881 gattatccat tgagtgaagc agattatggt tcattggtag cctattgttt agcctttgct
     8941 cgaatgaaaa cagccgaagc cgagataaga aaatcaggta cgtttatcac atgcgaaaac
     9001 ggagtaaaga aagccaatcc agcggttcgg gttcaatcac aagctatgag tgatttgaaa
     9061 aaacaagcca cctcactagg tatgacctta gaatcacgat caaaactagc tttgaacaag
     9121 gttaaaaatg atgaacccga agacccgttc aaagagttga tgaattcatg aatgattaca
     9181 ttgagaaagt cctatcaggt aagctgattg cacccaagaa aattatccaa gcgtgtgagc
     9241 gtcatataag cgatttggag cgttctaagt cagatagctt cccttatgtg ttcgatgaag
     9301 aacaagccac caaagcgatt aaattcattg agttgctacc atctacggac ggtaaagcaa
     9361 tcaagatgtt aggatttcaa aaattcattc taggcagtct ttatggctgg cgtactaaag
     9421 aagggaatta caggcgattc aatcgagcgt ttaccagtat gagccgtaag aatgggaaaa
     9481 cgtatatcgc aagtggcatg gctgccaatg cgttgattat ggaacaagaa ccagcagaag
     9541 caaggcaagt attgtttgta agtaacgctt tgaaacaagc taaattgggc tatgatatgc
     9601 tgtctaattc acttagaaac gtggtcaagt ctagtaagtt tttaagacca caactgaaaa
     9661 ttatgaactc taagattcag cacttgccct ctaattcgtt cgctatggca ctggctagtg
     9721 aaaccagcac gctagatggg tttgcaccaa caaccgcaat tcttgacgag tggcacgaag
     9781 caaaaactcg taaaacgtac aacgtcatta agtcaggaat gacccaacaa aagaacggct
     9841 tattgtgtgt tattagtacc gctgggcttg atttaaacgt tcctatgtac gaggaatact
     9901 tattgttaga tcgtgtgcta aaaggcgaag aacaagccga caggtacttt atagcgatat
     9961 gggaattgga cgatcccgaa gaaattcacg atcaagagaa atggatcaaa gccaatccga
    10021 tttttgaaag tgaagaaatc aaaaaagtaa tgattccaac cattcaagat gatgtgaacc
    10081 ttgctttgaa acaaaataac cttaattctg tattggtgaa aaacttcaat ttatggagac
    10141 aagcgagtga ggacagctat atgattgctg aagactggca ggcaaccgaa gtagaaccac
    10201 aagatattac aggcaagccc gtttatatcg gagtggattt atctaaaaca gatgatttaa
    10261 ctagcgtttc atggatcgta ccgctagata acggcgaact ttattgtgat tcacatagct
    10321 ttgtagccac caaatatggg cttcaagaca aagaaaagcg cgacggtttg ccttatcgag
    10381 aactagaaaa agctggtgag tgttccatta ctcaattaga aagtggaatc gtggactatg
    10441 accaagtatt tcagtttatt caagatttga ttcaagaaaa tgatttggaa tgtatgggga
    10501 tttgttatga cccgtataac gctaattcgc ttatcagtaa agctgaaaaa gccaactacc
    10561 caatgttaga agtaagacaa ggaacgatta ctctaaacgt tccgacccga acttttagag
    10621 aacaagttta tgaaggcaac gttattcaca ataaaaatac gattctcacc catgcagtga
    10681 acaacgctat tttaaaaacg gataacaacg gcattcagat taataaatca aagaacagta
    10741 acaaaattga tccaatagct gcattaatca atgcctatgt gtttgcaatg gattacttca
    10801 ccacaacgga aggagcgaaa gcagacaatg aattttatac aagtgaagaa ttttctttct
    10861 aattacattc ataccgttct tttacttctt ggattggtgt gtgtgttggt tgctatcacc
    10921 ttactaacaa atgtctacta tggcttgtta gcgctgggca tagtgcttat tggggtagcg
    10981 gtcatgctaa atacagaaca gaagggaggt taaaagatgg cattttttaa agcgagacaa
    11041 aatacaacgg gagatccttt cctacaacat gtggtatcaa tccaatcgga tgattacacc
    11101 accagcttta caagcgttcg tgcattaaga aatagtgatg tgtttgcagc cgttcgaatt
    11161 attgctagtg atattgcttc aagtccgatt caattggtca aaaacaatat gccacaagct
    11221 gataatgaac tggtgaagtt actaaacgag aaacctaatt cagaaatgga tggttggcat
    11281 ttaaagtttg ctttggcggt caatatgttg ctaaacggta atagctttgc agagattaaa
    11341 cgcaacggtg aaaaggtaga agaaattcac ttattaccta actcaagtgt aacggttact
    11401 caattagata atggtacgtt gtcttatcag attggtgata aaaaaagacg tgtgaagtct
    11461 agcgatattt tgcacttcaa atatttcacc caagatggtt taacaggatt accaccactt
    11521 tatgcgttac gtgatgaact gaaaattcaa caagctggca accgcacatt gcacaatttc
    11581 tttactcgtg gtgtcagtgg gtcaggtatt ttgaaggttc ataagtcaga tttagacgga
    11641 tcagcaaaga acgcaattcg tgaaaagttt gaagaagcca acggttcaag tagtggagat
    11701 aatgctctta gaacgatcat tcttgatgaa acaatggact acaaaacatt agaaataaac
    11761 accgatgttt tgaagcttat caattccaat gattggaaca caaaacaaat tgccaaggcg
    11821 tttggtgtac cgattgagcg tttaggcgtt gaaaatgaac attctagcac cgttcaaagt
    11881 aatctccagt atatccaaag tacgctgatt cattacttta atgtgtttgt gagtgaatta
    11941 gatacgaaac ttgaaaccaa tatccgcttt aattccgatc agttactaga gactgatcct
    12001 gaaacaaaag taaaaaatgt attggatcag gtcaaagggt cacttctcac gattaatgag
    12061 gggcggtcga aaatggggct accccccatg gatggtggcg atcgtttact agcaagtttg
    12121 aactttacgt atttagatac gttggagaaa tatcaattaa aagaacagga aggagttaca
    12181 ccagttgaat aatgaagaag aaaaggaaaa acggctgaca gaagaagctg agctaacagc
    12241 cgattctccc aaagtagaga aagaaaatga aaaacaacca acagacggca aaactatttc
    12301 aggctatgcg ttgaaattcg ggcaaccgtc aaaagattta ggcggctttg tagaagtgat
    12361 tacacccgaa gcattaaaag aggtggattt atcaaatgtg ttcttattat atggacacga
    12421 ttattcaaag ccactagcta gtgtcaaagc aggtacgttg aaattgaatg tcgatgatac
    12481 aggattacat tttgaagcag agctaaccga cacgacctat tcaaatgatg tgtatgagaa
    12541 tatctcaaaa ggggttgttg attctatgtc ctttgggttc gtgcttggat tagattcatt
    12601 cgacaaaaaa gaagatggca caattgaacg atcaatagat aaaatcaaag cacttaatga
    12661 aattagtgtc gtgaccgttc ccgcttatga ttcatcaaat gtccaagtaa ataagcgttc
    12721 ttacgaatcg tttatgagta acaaccaagc aaaacaaaca aacaatagct tagaatccac
    12781 ttctaaagca caaaaggaga gtaataacat ggaaaaaact ttaatcgata acgaaaaaac
    12841 agaattgcgt gggtatgaag aatatatccg ttcacaaggc gaagtgcgtg atggagtcac
    12901 tactgtaaat gcagcggcag ttgttcccga agaagtaatc ggtgaagtct ttgatttgaa
    12961 acgttcaaat tataacttag ctcaatatgc aacagtaaaa acagtatcaa atggacaagg
    13021 taaatatcca gtagcaacta accaacaagc agtgttagca acaaaagctg aacttgctga
    13081 aattggtgat attgacgctg aaatgtttac ttcagttgat tataaagtag aaactcgtgc
    13141 tggtaagatt gccttatcaa atgaggttgt ggaagattca gcagtgaata ttgtacaaga
    13201 ggtcaaagat cagttagcga aattggtaga aaacactgac aataagcata tcatggattt
    13261 attaaaaaca ttcactaaga aaacggctgc tacgttggac gatttgaaac aactatacaa
    13321 tgtggcatta gacccagcat taaataaaat ggtaattcta aaccaaagcg gatattacca
    13381 cctagataca ttgaaagatt cagatggacg ttacatttta caacccgatg tgacagcacc
    13441 tagtggtaaa tcattattcg gtatgccagt agtattgatt gcagatacat tgtttgccaa
    13501 tcctaaagct ggaacattcc ctatgattat gggggatatt gcacaatcta tctttgttgc
    13561 tcgtagaaat caagtaacga ctcaatggga aaaattcgat tactactcac aaggacttgc
    13621 agtgatcgtt cgcaacgatt ataagaaaat tgatcaaaat gcttcagtgt atattgagtt
    13681 tacgccagtt gtaacaccaa aagtatagaa aaatattggg cggcggttta tcccactgcc
    13741 tttttttcat taggagagat aaaatggtaa ttttggatag cataaaaaaa agtatgcgga
    13801 tcgatcacac tattgatgat gactttattc aacaattgat tgatacagca ggcgaatata
    13861 taaaaagtgc tattgatagt agcgcaacgg ataaagatat ggataattat cagcaatttg
    13921 atttggcggt gtcattactt actcaacatt ggtatttgaa ccgtcaagaa gccagcagcg
    13981 aacggatacc agtaacggta caagcattag tacaacaaat gagaggtgct tattatgcca
    14041 atcattaaga atgtaaatga attgactgag agagtcaagt ttaaaaagac aaaacgggta
    14101 aaagatgaag atgggcagat ggtggatagt gaagaaactg tatttgaatg ttgggctaat
    14161 gtgcgttcac aaatgctaaa agacgtgctt gctagtgtag gtaccattct tgaaggaacg
    14221 ttgacgttta ttattcgata cgatcaagat tatgaactaa caaacgatat gaaagtagct
    14281 tggaaaaaca agagttataa aattatttca atcaatgaag gaacggcgtt taaagattat
    14341 acaacgatca tagctaaaca gatttcttag aatgattaca cttgtaaacg ttgtgggtat
    14401 ttagtataat taaggtagta aatgaagggt tagctgcctg aattttgcaa gacttagcta
    14461 gtcgaaatct attgttggac tgaaaattgt aggtgtggtt gcaaacatgc tggactaaga
    14521 aagatgatag atgatgaacg ttcaatttta atacaggcat gctaggactg attggatggt
    14581 tttggcaagc tgattgtgta gaaatcaaag aacacgtctg ttgtggacgt gttttttttg
    14641 ttataattca aaagaggtga tttaatggac aaagcagagt ttacaaattt ttattggaag
    14701 tattatctac atttagaaaa tgagtttatt aataccacag attttgtgat gctcgatgag
    14761 aataatttca aaacattctc tattgaatat caaaaactac tactagcgat tggttcggag
    14821 tgtgagatta ttttcaaaga actttgcgga tttgatagca gtagcaataa aagcataact
    14881 gattttaaag ctgttattaa atctagcgaa ttaatgtgtt tggataatgg tgttagggtt
    14941 atgaattctt taacattgac ttcactaaaa ccttttggag atgggtggcc tgaagataca
    15001 ccagattggt ggaaaatata taacagagta aaacatggtc gttcttcaaa ttataaggaa
    15061 gcaaatttgg aaaatgtgtt gtatgcttta gcaagtctat atttattaga ggaatatttg
    15121 cataagaaag taatactaga aggtgaagta gactttataa gtccagagtc aaatctattt
    15181 acgttatctt gggaaagaaa acattcgtcg atgcaaaaag tgacgtttga aaaagtggat
    15241 tcaaattatg tagctccact cattgatttt aaagaacaag aagaaattta aaaaccccca
    15301 cggcttattg aagtttttgt atgccatatt gtatgccatt tggtttaaat cgcttgaaaa
    15361 atagtgatag ataactctaa ttcatttagt cataaacgct gttttgataa cctttatagt
    15421 tctttgatat gggtttctca ttcatggcgg aagaagaaga atagaacaaa agaatgaatt
    15481 aataagatat aaaaaaaggg attgtgacaa acgtcttgtc acaatccctt tttccaaata
    15541 aacgatgttc aatcagctgc ccctcggcat tcgctcgaaa aacggcgaaa tatgaagaac
    15601 tattttgcca tttgtttctc taataatcag gtcaaaacgt tgacttcaca gtctcttcct
    15661 taaacggtgt tctcctgcca actcctcggt cacaagtcac aatattcaac aaacatgaga
    15721 agctgttttt tgaaattgtt ccttgtgact cggagctgaa cggcaggctc acgacctctt
    15781 tcttaaacgg tgttcaaaag cttgcatctg cggtaataag ttcaaccaaa cgaaaattat
    15841 gaggagctat ttttgtttgg ctgttcttat tacttgatgc aggacagctt tttcacaacc
    15901 tcttttcgtt tagcactaaa tttccttaaa aagtagaaaa gctttcgaag cctcgtttgt
    15961 ttcttttact gtataataaa agaaaagagt aacaatcgct aaaagatata aacaagagaa
    16021 aggaaataca agatgattgg tctgatttat tttgtggtga tcgttctggc gaacacagtt
    16081 ggcgctattt ccgggatggg tggaggcgtg ttgatcaaac cgattcttga tcttatcggc
    16141 gcccattctg ttgcagggat ttctttttac tcaacagttg cggtattcac gatgtccatt
    16201 gtttcgactg tgcgacaagt atcaagcggg aaatcactga attggcagat tgtcggttgg
    16261 gtatctagtg gagctgttgt tggaggagta gtcggcaaca ttgtattcga agttttttta
    16321 cagttatttg aaaacgagaa gcatgtgcag ctgatccaaa tttttttgac ggtattgacc
    16381 ttggtttttg cgttcttcta caccaagcat catcagccaa aatttcattt gacgtcatgg
    16441 acttggtacc ttatatgtgg gggggttctg ggctttttag ctagtttttt aggtattggt
    16501 ggtggaccag tcaatgtttc tttgttgatg ctgatgtttg cattgccaat aaaagaagca
    16561 acactatatt ctctatctac gattttcttt tctcaactgg caaaattggt aacgattgct
    16621 ttaacaagta gctttatgcg ctttgattta tctatgttgt tttatgttat ccccgctgct
    16681 gttattggag gtttgtgggg agcaagattt agcagggttt tgtctccaaa aaaagtgacc
    16741 tttatttttc aagtaattgt cctcgtggtt cttttggtca attgttacaa tgcctttgtc
    16801 atcttacaaa cattaggaga atctagacta acgcaagtca aaatcactga aacatattgt
    16861 tctaaatgaa aaaaagagta tactatgata aaaaaattca ttttaaaaaa tcagaaattg
    16921 gctggtgatt tggatgttac gggaaatgcg tttagaagat gcagaagcac tacgtgaaat
    16981 caatgcggat caattagggt atgatatacc attaaccgtt acggtgagac aaatgaagaa
    17041 actgctgaag gagccagaga aaaatttttt cttggtttat gaagatccta cttctaaaaa
    17101 agcagctggc tatgtacaag cggagtccta tgaatcgatt tttagcgatc caatgttcaa
    17161 tattatggca cttgctgtgt ctaaatatgc tgaaaaaaga ggcatcggaa aggctttgat
    17221 gactggcgta gaagaagaag cgaaaaaacg aggaataacg acaataaggc ttaattctgc
    17281 agaatacaga gtagaagcac accaatttta tgaacacatc ggttatcatt ccgataaaat
    17341 gcaaaaaaga tttttgaaaa tcctgtaaat ctttatcaaa aaaatacccg atcaccaagc
    17401 cgatacttga tgatcaggta tttttgtttt tttgactaag aaagtaattg catcaagaaa
    17461 ccagagatga tcaaaacgat ggcaccacca agtcgattgc ccatttgagc aaaagcaata
    17521 agttccatcc gattagctgc agataagacg gctacatttc ctgttccgcc catcgagttg
    17581 ttgcataagc cagcagtaat agttgattca attggatata aaccaaacaa acgaccgaca
    17641 aatcctgaaa caactgaaat cgcgataaca cttgtcagac ataagacaac aaattgccat
    17701 gtcaaagcag aagctaatac attcagattc agcaacgcaa taccgatacc ggcaagaaca
    17761 gctgctgtca agtttttgac aatcaagtta ttgaacatga tagctgcatc ttcataatac
    17821 tctggtaata ggttggcgat tttacagatg acaacgataa taatcataaa tgcgtaagca
    17881 tggactttag gaacaaaata gttaccaatt tgtcctaaga tgaagaaagt caatgatacc
    17941 atcaaaccaa cacctaactg tggaatggaa ggtttcacag ttcgaggttt tccatcgcca
    18001 agatcgcctt tttccattaa tttaccattg ccgttgaatt ttggcattga ttgtccagca
    18061 cgagcaacta atgctgcacc gatgatagct aagacatttg tcattgctgt cgcaggaatc
    18121 aggcgggaaa tgatagaaga agcatccgta cctaaaacat ttgcataaat cgttgataaa
    18181 ggaacggctc cggctccaac accaccagcc atcgcaggta atgagatgta taaaacggaa
    18241 tttgcaaaac catttccgat aagcatgccc acgagtccta cggcaaaaaa ggagacgacc
    18301 attgaaataa gtgcaacggg aataaaacga acagaagctt tcatcaatag attacggttc
    18361 ataccaagga tgctaccagt aatcaaggca gcaatataaa agtcccaaaa gcccatattg
    18421 ctgacaaagt tttctgtgga tttcactaca tattcaggta agatcccaaa tgtagcaatc
    18481 gcagcagaag cgaagatcgc aaaaacggaa ccaccaccca aataactttt gacgataggg
    18541 atttttgtcc cgataaaatg aaataaatta ccgaaaataa ccaaaactgc gattggtcca
    18601 atcatattcg tcggtaattt ccctaaagcc attgcaatga tcaggacaag gaccatgatc
    18661 aaataaagtg gcaaacttac gccggtgatt tttgtggacc aaaaaccttc ttttttcttt
    18721 tcctcaactg cagttgcagt tgttgttttt tgtgccattt ttacagatcc tttcttattc
    18781 tgtatcatat gaaaaaagcc aaagaaaagc gacaaaagag caggagttgg ctggccgctg
    18841 ttttgccgca gtcgcttttt tctttttaga cgtcatacaa agtttctgta tgttctttta
    18901 ctataacgat cttaatcttc taaagattta tattcaggaa cccatttagc agattcaact
    18961 gcttctttga tatccgtgat ttcttcacga ttcaagtttt gtgcgacaac tgattttgcg
    19021 acagtttcag caatcgtttg agaaaattca gtgatttttg ctactggagg caagatagct
    19081 gctcctggtt ttgttacatc aacgattccg cctaatgctc gactagcttg agaaatgatt
    19141 tcagcattta ctcgtgtagc tgttgaagca atcaaaccaa gtcctaaacc tgggtacatc
    19201 aaagcattat ttgcttgacc gatttggtaa gttacaccat tatattcaac atcagcagca
    19261 gggatacctg ttccaactaa tgcttttccg tccgtccatt ctattaaatc ttttgctttt
    19321 gcttctgcca attttgttgg attagacaaa ggcatgatga tcggacgtgg tgtatgagca
    19381 gccatttctt tcacgatttc ttcagtgaat gctccaggtt gggtagaagt accaatcatg
    19441 attgtcggat ggatcgcttt tacaactgct tctaagtttg tcaattcatc agcattagtg
    19501 aaatctgagc gtttgcgagc gaatgggatt tgaccaggag tcaatccttc tgtatcttca
    19561 aacaataaac cttgtttatc tacttgatag aaatgttggc gtgcttcttc ttcaggtaca
    19621 ccttgacgga tcatctcatc taaaaggatg tttgcgatac ccacaccagc agtaccagca
    19681 ccaaatgtca aaattatttg atctttcaat tgttcaccgg atatattcaa tccgcctaat
    19741 acacctgcta ggacaacaat tcctgtacct tggatatcgt cgttgaaagt agtgatttga
    19801 tcttcgtatt tttctaagat cgctgcagca tttcctcgtc caaaatcttc ccaatgcaat
    19861 aacaattctg ggaataattc ggtagctgat tgaacgaatt gatcgatgaa ttcatagtaa
    19921 gtttcgcctt ctacacgagc atgacgattg cctaagtata agggattatt caataattct
    19981 tcattattag taccagcgtc gatcgataca ggcaaaactt gtgctggatt aataccagca
    20041 gcagcagtat agaccatcaa tttgccgata gcgatgtcaa caccgttcac accccagtcg
    20101 cccataccta agattccttc tgcatcagtc acaacaatca aacgaatgtc tcgtccatct
    20161 gccgcgttct tcaaacttgc tttgatgttt tctggttcgt cgattgaaag aaatgcagca
    20221 tcttgcggtt tcaagaaaat ttcgttgtat tgttcgattg aatccgcaac gacaggatca
    20281 taaacgacag gcatgaattc aactaaatgt tcgcccatca atttataaaa caatgtccga
    20341 ttcgtattga atagattcat taagaagata cgtttttcca aatctgtttg tttgcttaag
    20401 tattgaccat aagcttgaac agattgttgt tccagtgttt ggacagtact tggaagcata
    20461 ccagtgattc catattttgc ccgttcttct tttgtaaaag ctgttccttt atttagaaaa
    20521 ggattattta ataagtttaa ccctgtaagc atgaatgatt cctcctaagt tttaatacaa
    20581 acgaagtata gaagtcagat gatgatatag tcaaaaagag caggtatgat aaattttatt
    20641 tatatgtaat atagccaaaa gaaatcaaaa tagcagtatt tgttcttttt atatcgacaa
    20701 tccttgcttg aatactatgc gtatctctta tatgctagag aaagaaaagt agaagaataa
    20761 gggatagatg gaatggataa ataggatttc tgaggaaaaa agcacatgat agcgttgata
    20821 ggagtcacct atgtcaggtg ataaaaatac ataagtagaa aattaagagg aggaagagaa
    20881 aatgaaagaa gttcaattga ttagaaaaag cgaactatca gaaggcggtt gcaatgcatg
    20941 tggcgtagta gaagcgacaa gctatacatt aaaattagat tccaatcaag caataatctc
    21001 tgaactgaca gtaggcggtc ttgtggacag tctggcgctt gctgaaggtt ttactggaga
    21061 agatatttat gagatgtttt cagaagtccg tcagttaaaa aaaggagaaa aatgcataga
    21121 ggttcatcat gagagcccga atgtgaggtt caaacgtggt gataatgaga tgatcttcaa
    21181 gaatcatgtg tctgatcaca ctgaactata tgaaatcgtg aatcaaatac tgtctgggat
    21241 ttttgaatta ggaccttatg agttcaagga agaaaacggt aatccaaaat taaatgaaga
    21301 atggcaagaa acgattgaaa cacaaagaaa caatccacac ttatttcaat agtcttccac
    21361 agtatttcgt aaaaatgttg atgaaaaaga aacaccgtga atcagaggtc gtgaaaaacc
    21421 tgccctgcat caagtaataa gaacagccaa acaaaaatag ctcctcctat ttttcgtttg
    21481 gttgggctta ttaccgcaga tgcaagtttt tgaacaccgt ttaaggaaga gactgtgaag
    21541 tcaacgttct gacctgagta ttagagagac aaatggcaaa atagttcctc atattttgcc
    21601 attttttgag ctaataccga gggtcagctg attgaacacc gttttatcga gaggttgtga
    21661 aaaagtcgct tagtttcgag tagtaagaaa aattttgtga aaatggcttt ccacattttt
    21721 gcataaattt gacttaatac cgagaaaatg gcttttgaac accgtttatt caaaaaaagg
    21781 gactttgaca ctacttttgt caaagtccca tcggtttttt atctattttt attacaatca
    21841 tttcttccag agtagtgaca tctggaatgg ctgaaatgta aacagattat ttgcctgtat
    21901 caatgtcgaa gagtaatata aaaagtgtaa acgctatcat attgttcatc attcaaattt
    21961 tatagagaga aggcattgag atggaaaaaa catatcaagc aggtacaaat gaaggaatag
    22021 tagattttat caatatggaa gatttagaaa tcgcggcttc acaagtgatt ccagctggtg
    22081 gttatggtta catcagcagt ggtgctggcg acttatttac ttatcaagaa aatgaacggg
    22141 cattcaatca tcgtttgatt attcctcatg tattaagaga tgtagaatta cccgatacaa
    22201 ctacacattt tgacgaagaa atgctgactg caccaatcat catggcacca gttgctgctc
    22261 atggattagc tcatgtgaag gcggagaaag cttctgcaaa aggtgtagca gattttggga
    22321 cgatctatac agcaagttct tacgcttctt gtactttaga agagataaga gaagcaggcg
    22381 gggagaaagc accgcaatgg tttcaatttt atatgagcaa agataatgga atcaatttgg
    22441 atattcttga agtggccaag cgtaatggag caaaagcaat cgtattgaca gcggatgcaa
    22501 cagttggcgg aaaccgtgaa acagaccgca gaaacgggtt taccttcccg ctgccaatgc
    22561 cgatcgttca ggcttatcaa tcaggagtag gccaaacgat ggatgctgta tataaatctt
    22621 ccaaacaaaa acttagtcca aaagatgtag aatttatcgc tgctcattct gatttgccag
    22681 tctacgtgaa aggtgttcaa tcagaagaag atgtctatcg atcattagaa tctggtgctg
    22741 gtggaatttg ggtatctaac catggtggcc gtcaattaga tggggggcct gctgcgtttg
    22801 attcgttgca atatgtggca gaagcagtag ataaacgtgt accaatcgtg tttgacagcg
    22861 gtgtacgacg tggacaacat gttttcaaag caatcgcatc aggtgccgat cttgttgcta
    22921 ttggcagacc cgttatttat ggattgtctt taggaggaag tacaggagtc catcaagtgt
    22981 ttgatttctt taaaacagaa ttggaaatgg tcatgcaatt agctggaaca caaacagtag
    23041 aagatatcaa aaaaataaaa ttgcgtgaga atcgttttat ttaagaaata aatgacgaaa
    23101 aaaataggag tgcggcagat gatgccgtac tcctattttt atagttcaag gatgtcacta
    23161 atagaataat ttgaaacgaa aaaataaaat tgaaatattt tttcatactt aataaaaaag
    23221 gaagaatatt catgtaaacg attttattgt ttttttctct tttatacaaa aagggtcata
    23281 atttcaagta agcggatgaa ttcatgagga ttttttgcat actgtctcta ctatacttag
    23341 gtcactaaga aaaaggagtg atttattatg aaaaagaaca tgattgggac attattactt
    23401 tcaacacttc ttctaggcgg cttggcaaca ccagcttttg ctgagggtca agcgacttca
    23461 aaaggagata ttacctttac tgaaccaaca aataccgttg agcctcttaa ccctactgat
    23521 ccttcaaaac cagtagagcc agcagatccg gaaaatccag caactggcca gacaggttct
    23581 ttaacattgg atgtagttcc tgaattgcca tttggtacac acgagattga aagcggaaca
    23641 aaaacgtatc aagtagacgc ttcaaaaaac gatacacctt atctccaagt atcagatcgt
    23701 cgaggtgtag gtgcagatgg ccaagcacaa gggtggaacg tgacagtttc ggtttcagat
    23761 tttgtaaacg gttcacaagt tttgcaaggc gctgaattag attttggaac atccactgtt
    23821 aaaagtacgt cagataacga atccactgga ccaactagtc aaactgtaac tgggttgagt
    23881 aaagcaagtg cagcgacacc aatatttaca gcagcaaaag atcaaggtct gggaacatgg
    23941 ctttctgttt atgatccagc aaatatcaca ctgaaagtgc cgaaagcagc agctggaaca
    24001 ttcacggctg atttgacttg gaacctcgtg gctggcccag tagcatagag tatgaaataa
    24061 attcaacaaa ctgcggtgaa aatactatag gtgaaggatt ttttaccgca gttgttgttg
    24121 aaaggatgtg gtggacaatg aatcaaagta aacgactgtt tgtttcgttt ttttctattt
    24181 taagtctatt tttcattttt ccgtcaatca gccaagcaaa ggattcagca ggagactttg
    24241 gaatcaaacc ggtatttcca gagaaccaaa tagataaagc aatcggttat tttgatttat
    24301 tagtggcacc ggaacaaaat cagacactag aagtaattat cagcaattct tcagatgaag
    24361 aacgaacatt tgaggtctct gtcaatccgg cggtaacgag tgatggtgga acgatcgatt
    24421 atagtcaaaa aaacccaacg ttagatgaga cattgccgtt tgatgtccgt gacgttttgc
    24481 tcattgcgaa aaaggaaatc aatgtatcag cacatgcaga aacaactata cctatagaag
    24541 tgaaaatccc agcaaaaagc tttaagggac gtgtattagc gggtattcat gtttcaccta
    24601 aagaagaagc tgaaacagaa aatgctacag aaggagcaca aatcaaaaat cgtattgctt
    24661 ataatctcgc agtcgtttta caagaaagtc aagagacgat agaaccggat ctgaaacttt
    24721 tatcaggaga tttggacgag gtcaacgcaa agccaactgt tcagcttcgt ttccaaaatc
    24781 ctcagcctag gattatcagc aatttgatat ttacgagcaa gatcttttat gaaaatcagc
    24841 tttatattga aaatacgtct aatgaatttt tagttgcacc aaattcgaat tttcacttga
    24901 atcttgattt agctggtgat aaagcaaaag ccggcgatta ccgcgcagaa atcatagcaa
    24961 aatcaggcga cagtaatgaa tggcgattta cacaaaactt tacgatcaaa aaagaaaaag
    25021 cacaaaaagt aaatgaaaat tccgtttttg cagtacaaga acaatctttc ccatggcttt
    25081 atgcaggatt ggttgctgca gttctagtgt tatggttgat tttgctgttt ttgtgggtcc
    25141 acaagaaaaa gaaaaaagga gaaacaacat gatgaggtga tttcgttgaa aacatcgatc
    25201 ttattgggag ggattattgc aagtttgctg ttcttcagct ggcaagagcc agtccaagca
    25261 gataccaaaa gttcaggtac gattacattt tatgatctaa gtccagttcc gcatccaagt
    25321 ggttcagtca atggcgcatc aaaacagcag acacagctac cgatttataa agaatctaat
    25381 caacatggcg tattcccgga gacgaatgaa gaaaagatcc gttttcttta tttgatcatt
    25441 ggtatagaat tatggcttct tgcgtggttg ttgttatgga gaagaaagga aaaggaggat
    25501 gaacatgttg ctacaaaata aattttcatt ttttcgctcc ttctttttta cttcgctttt
    25561 tgttttaagt atatttatct tttcaccttc ggcagaagct gttggagcaa cgcctcctgc
    25621 catttcttat gatccataca cgtatgaaaa tatcgtacct ccaaatggtg gacgtagtgc
    25681 agtcaatggc gggaagcttg tccaactaac tggggctaac caattgccta aattgactgc
    25741 tacttatttg aacgatggtt caaatgatcc ttggaaaggt ggcacggtcc gttttcattg
    25801 ggaaagccat gtgaaactaa caaatgtact tgatttggtg aatatcactg cacaaggatt
    25861 tgcatttgtg gcgatcatca atttgccgga acatgtatca agcagtgatg tattaaaagc
    25921 aattgactgg aacaacgcct acttgtatat tgccggtgcc cccatcaagg ttactagcgg
    25981 tagtttatta tcagcaggaa gccatacctt gcgttttggg atggggtcgt gggatacaaa
    26041 tactctattg gcagatatta ttgctattat tacgcgaggc gaattcaacg tggacgatat
    26101 cccgcttcaa tttgatgtta cagctaatgt cgcgaagatg acagaaaacg gagataaata
    26161 tgatacgagt ccaaacaaaa ttttgaccaa gggtaaatta caaccttcta tgtctaaaaa
    26221 ggccgttttt tctgttgatt tttatgattc gaataatatt atccaagatc gtatgttcaa
    26281 ttcgatttta gctccagctg caggtagatt ttatcctaaa ttaactggcg gaaacttgaa
    26341 tccaggagca tatgcatttt ctgcaagtgc agagataaat acgtggaata gttacatctc
    26401 aacaagtgat tcaacaggaa aatataatac atttgctgat accacagaat acgtggatgg
    26461 aaataaccag aaccttccag gctctaccaa tagtcggaca ttgacgatgg ggctgactga
    26521 aggacgtttt gatcagttgc catttagtcg ctttgatcgc gtagtcaact attttacagg
    26581 aaaaaacgtt acacaaggag caatactgac tcatactcca gcaagcacaa gtggattgaa
    26641 tcagacagcc aatatcgtgt acagtgggaa agatgcgcaa ggcggattgc tttctcctgt
    26701 tgctttaaag gtattggagc agtacaagct agacggaacg gttttaccaa caaacttaac
    26761 agccgatagt cagtggggaa agctcctttc ttctgcatcg taccaagtca cggccaattg
    26821 gtcagcaact gaactaaaaa agggttcgat ccattacagg ctttattcga aaggaaccca
    26881 aaaattagcg acaggatgga cagatcaact tttccaaacg atccaatcaa ataacggggg
    26941 tgtaaataca gctacttcta cactacctgc attggcttca gggcaatatt attttgatta
    27001 tcgcttggtg gacgatgtac ttactaacat gtatccgtct tttgcgtaca aatggcagtc
    27061 tgaacaagct ggaatcacca ctcttcctca aataacagtg gctaattttc catctgtgag
    27121 tgcagatagt cagctaaaaa accttagcag acaacctgag acaggagatc ccctgtctgc
    27181 tctatcagga gatacgattc aagaaaatgt gacattcacg ttaacaaaat ctggggatgc
    27241 gataaccgac aaaaaaatca cgatctcact tcctgaaaat actacttata tcaatggttc
    27301 cttaaaatta aatggtacaa ctatcgcaga taccggcatt caacaaggag tttctgtccc
    27361 agcagatcta ttgagcaaaa taggagatac cattcatctt acttacaact atcaattaaa
    27421 tactgtagat acttctgtac aatccgtcag catactgaca aaggcagctg tactttccag
    27481 caatattaca ttagcagatg gtgctaagct tcctaaccca gttgtccaaa catctgctaa
    27541 aacaattctt gtccccaaac aagaattaac attagttaat gtaccagatg attttacatt
    27601 tggtaacgat ctccccaaac cgttgaagac aagttattat gaagcaaaag gcgatttttc
    27661 ttttgatgtg cgggatactc ggcttccaag cacgtctcct tggcaactga cagggacatt
    27721 gacttcttta tttaagaatg atcaaggtca agaattaagc ggaacaaaat tatacttcaa
    27781 tcattctgga tcaaaacaat tgattcagca aggtcaaaac acgttgattt atgagagtga
    27841 tggaacagct aaaggagagg ttctcgttga ctttcccgat accgatggtt tactcttaga
    27901 ggtaaatagc agtacgaatg ctcaacctgg cgcaacgtat caaggcatgg tcacatggga
    27961 actgacagct gggccaacca gctaagtgat tagaatttgt atggatctgt gataactgtc
    28021 acagatcctc tttttcaagg atgagaagga aacttctgct gttaaaatca gaaatgcttg
    28081 gaggagtgga cttggaactt ttcagtttgc ttgaaaaaaa tgaacaacgg caaatcaaac
    28141 ttttccaact tttattagag gaaaaaggag agatttccgt taataacgta cttacccgct
    28201 tatcagttga tcgggctacc ttgaaagaag atctgtttta tttacaagct aacttggaaa
    28261 atatcaaaca attggaaatt gttatccaag aagggaatat tttattaatc agacatggaa
    28321 atatagcagc agtcgatgtt tattatcatt gctacttgcg ctattctaca aaatatcaga
    28381 tacttcttta tctgttggaa aatggctcat ttgatcggca gaaacttgtc atggaactta
    28441 atatcagttc ggctactttg tctcgcagag tgaaggaatt aaatgattct ttaaatgagt
    28501 ttcatctgaa aataaaaagc gggcggctga ccggtccaga aagtcaaatt tgttattttt
    28561 atttccaatt attttggttt ggacgtcctt atcttgaaaa caaaaaagaa tacagtgatt
    28621 tatcaggaaa cactttttta gatctgctgc aaaaagagtt tagttttact attacagaag
    28681 aaggacgatt gaaatttgaa atatggcttt ccattatgaa gaagcgaatg cgctgtacga
    28741 aaaaatccaa accagattat agcaatcttc ctgttggatt gtttcaaacg acacaatttt
    28801 tattggacct ccatacattt ttgacccgtt acttctttca atatgccttt ccttggaatc
    28861 aaaatgaaac gttggttttt tatcttttca tgatcagtaa ctttacatta gatacacata
    28921 actcgcatgt ccaggagttt ttgataagcg aaaaatacaa agacgacgta gtagctcaat
    28981 tgaatcgaac gtttaaacaa tcgatagaag aatatttctc tttttatgtt tttccagaag
    29041 agatttcgca aaagattgcg ttgacagtga tgcaaaatca cgctcatttt gcctatttta
    29101 gaggatggat gaatattttt ggccaagaag gattaaaaca gcggttaact gaagtagaag
    29161 ataaacaatt cctggtttta tgtgaaagat tggtcagaca aacatttgct attgttgatt
    29221 ttactgaagt agacgaggaa aatgcccgct ttgaattatt tgctcgctat gcatctattt
    29281 tgcggacgct gatcaagcag ttagaattac gtctgcaaat tgcttatgat cttccttatg
    29341 aaaggctaat ggcggatatc gtgaaagaaa tcatccagga acaattgctg aatacgatca
    29401 aatatgattt agtcgaatac gagaaagaaa agcagtatga tatcattttg actagccaat
    29461 tgaaagagta cccgtcacag aagtccgcta aagtttttgt attcactagc aacgaatata
    29521 attatgattt cccctatttg aaccaatttt taaaagaatg ttatttagaa aaattgaatt
    29581 taaggatgaa taaaacatga aaatcgtgat cattggtgct tcccatgcag gcatcacagc
    29641 tgccctaaat ctaagaaaac ttcaaccgaa agcagaagtt ttactgatcg atgaagatca
    29701 taaagatgga ctaggctatg tttcaaatgg aatcaacctt tatttaaaag gaaagatacg
    29761 tagtttagct gaagttgccc ataacatgcg gactcttcaa gaaagtgggg caaaactgat
    29821 caccgaatgg agagtaactg aacttgatcc agacaaacat cagctcatcc tcgcatccaa
    29881 agaaggaaaa aacgagacca taacctatga taaattaatc gtagcaacag gttcctctcc
    29941 tgtcaccttg tataaacaaa ttgaagctga aaatgtctac acctataaaa atctagtgca
    30001 atctaagcaa gtacttgccg ctttaaaaga agcaaaagaa gtagtgatct tcggtgctgg
    30061 ttatattgga ttggaattag cagatgcttt gagaaataaa ggatacatta ttcatctagt
    30121 tgattatatg ccgaatgttt tatcaagata tttcgataag gatatgatca acagttttca
    30181 aaatcagctg caaactaagc aaatcaattt ttatccaaat gaattcttga tcgattggaa
    30241 aaaatcagaa gagaaagtag tatccgtaca acttctatct caagcaataa aggcagatat
    30301 ggtcattttt tctgcccaaa ctcgtcctaa tacgacattg ttaaaagaaa aagtggcttt
    30361 gtatgaggat gagactgtga tagtcaatga atatctgcag acaagtgatc cggacatcta
    30421 tgcgattgga gatatcgtcc cagtcagttt tgacaaaaat aaacggcatc tctttttacc
    30481 tttagttact cgagctgtac atatggcaag agcagtagcg ctaactttga gtggtcagcc
    30541 aaccgcttac gacctcagac aaaagataac agcagcagtc attatagact actttttagg
    30601 aactgtaggg ctgacagaag atgaagcgcc attcttggaa caaaataccg gttcgtgttc
    30661 aggagaattt gatctatttc cacaatacga tgaagaaaac aaaacagtaa atgcaaagct
    30721 gatctaccat ccggatacat tagaaataat tggcggacag ctgataagcc aagaattctt
    30781 attatcagat ttgaacctgc ttgcggatat cgtgaaacac aaaactacga ttccacagct
    30841 agcagttgag gattttggat ttctgtctga acacacctct cgttttcact acctcaatga
    30901 gttagctttt aaagtactag ctaagagagc aaatagcaat agagtagata aaagactgtg
    30961 agaaatatca cggtctttta ttgtgtgggg atataataaa tattaatcaa tcgagaataa
    31021 aaaattcata taatgaaata gcggaagaat tttttgagca taatattcgc caaaaattta
    31081 tcaagtgata aaattgttgt ataaaatgat tatttcagga ggaggagtta aatgttttta
    31141 gcattaaatg aaattatgca ttcaaagtta cgttatgcgt tagttgcagg ggtgatgttt
    31201 ttgatcgcct acctggtatt ttttttgact gggttagctt atggcttagc tcaagataat
    31261 cgaacagcag tcgacaagtg ggaggcagat tcgattgtgc tttcgaaaga tgcaaattca
    31321 aatctaggga tgtccatgat tactaagaag atagcagaag aagtcgaagg tgggaaagtg
    31381 gcgtatcttg cccagacacc tggagtcgtg actagtaaag acagtacaga agaaggaaaa
    31441 atcaatgtta gcttcttcgg tatcgataaa aatcaattca tcatgcccaa tcttgttgaa
    31501 ggaaaagctt ttgataacga tgatgaggca gtaggcgata ttagtttgaa agaagaatat
    31561 ggtctagccg taggagatac agttaagtta tctggtagtg acaagacgtt taaactaact
    31621 ggctttacgg atcatgccaa attcaatgtc tcaccagttc tctatacaac catcaatgct
    31681 taccaagaga tccgcttcga aaaagaagat acaagtgaaa atgcacggat taacgcaata
    31741 gttgtcagag gtaaaatcag taatttacct gaagatttag aacagatcaa aatttctaaa
    31801 ttcatcaatg aattacctgg atataatgcg caagtattga cttttggatt tatgatcgga
    31861 tttttgatcg ttattgcggc tattgtgatc gggattttca tttatgtact gacgatgcaa
    31921 aagattaata tctttggtgt aatgaaagca caagggatca caggaggatt tattgcgcgt
    31981 tctgtagtgg cacaaacatt cattttatca tttgttggta ttcttcttgg tctattagga
    32041 acagtgggaa catcccttgt tctacctgat gcggttccat tccaaagcaa ttggctgttt
    32101 tttggcgtca ttagcttgtt gatgctggta gtagctgtgt taggcgcact attttctgtt
    32161 cggacaatcg taaaaatcga tccgttgaag gcaattggat aagaaggagg aagagcatga
    32221 aagcaataga atttaaagaa gtagaaaaaa gtttccaaga tggcgaccaa gtagttaaag
    32281 cattgaaaga aacaaccatg agtatcgata aaggggaatt tgttgcaatc atcggtcctt
    32341 ctggttcagg taaaagtact tttttgactt tggcaggcgg attgcagacg cctagcagtg
    32401 gctctgtatt tatcaatgat caagaattca gtaatcaaaa agaaagtgaa cgcgttaaac
    32461 tacgttttaa agaaattggc tttattttgc aagcttccaa tctggttcct tttctgacag
    32521 taaaaaagca gttattatta gtagataaga tcaaacatga acatcgtcaa aaagaagcaa
    32581 aagaattatt tgagcagctt ggcgtggata agttgatcaa caagtatcca gaagaactat
    32641 ctggtggaga acggcaaagg gtcgcaatcg ctcgtgcatt gtacaatgat ccgtccatta
    32701 ttctagcaga tgaaccaact gctagtttgg attcagaaaa ggcacgagaa gtagtcgata
    32761 tcttggcaaa agaatcaaaa gacaaaaata aagcaacgat catggttact cacgatacac
    32821 ggctgattga caaatgcgat agaatattta tgatggaaga tggtgtattg aaagaaaaag
    32881 aataaccaaa aagcaggtgg aaaaatggtc catcgataca acaaagatac acagcaaaaa
    32941 attttgaaag aagcgactga cttgtttatg tccaagggat atctcggcac ttcaacaaga
    33001 gagatcgcac aaaaagttgg gatcacccaa cccaatctct atcattattt cggtgataaa
    33061 gaaaaactat atacggcagt tttagaaaac cacttaaaag atgttggaaa agctttgaga
    33121 gaaatcgttc aaacaagcga aacgggattt caagtaacct tgacaaaaat ggcgcagttt
    33181 ttgattgaga cacatctggt cgatttgttt ctgatgcttc acgatcttga aagcaatctt
    33241 tcaaaggaaa caagagatca tcttttcttt ctatggaaga aaaattatcg tgaacctttt
    33301 gaagaaatct tttcagcaaa ccaatctgtg ctaagaaatg ggatttcaaa agaaatcgca
    33361 gcaaggcatt ttttcttagt gttagcacct tacatcactc ggtcgaaaag acctgtggaa
    33421 gaaccgctaa atgtggcgca attgatcgat ttatatttga atggtgtatt aggagaagcg
    33481 taaagctgtt atatagggag aaaaatagtt aggtgaagaa gcaagatatg acgaagatcg
    33541 ttatatcttg ttttttttat ataggtagtt tttcataaat acaaatttgt tattctctca
    33601 tgattatcag ggtatatttt tatttattat gtcggtgttc caggaagtgt tttaatttaa
    33661 taacgaagaa attaattgtt tgtagaatga aggaaactat ttattgggta gatgaatcac
    33721 cacgaatagt caaaaggaga tttcaggata tgccaaaaat gaaaaaaatc attttagcag
    33781 taatgttatt ttctacggtt atatctttta cagccccttt tttgcgtact taagctgatt
    33841 ttaagttttg acccttagtc tggatctacg aggtgagagt caagaatgaa aaaaataatt
    33901 ggagcttttg tatttgcaat cattatcatt attatctgtt ttcaaataga tgtttttggt
    33961 caaaaaaaga tagttggaca aacggtcagc agtacgaaca gtacggttac aaagacaaag
    34021 gaatcatttg atgatacaga acaagagaca ttaatcaaaa tcggaaaaaa tgaccgtaca
    34081 ctatatacag atgactcgct aactacccca cttgcaacta taaacggcgg agagctggcg
    34141 gagtttcttt ctgaaacaaa aaatgcttat cagatcaaga caaatgatgg ctatactgga
    34201 tatttagccc tcgaagatgg aaccaaagtc acaaagaata tacaaacaaa accggaagag
    34261 ctatctgatg cagtgattgt attagatcct gggcatggcg gaaatgatac tggggcatta
    34321 agcaatgatg aacaaacaga agaaaaagat ataacattaa gtacagccat aaaagtaaaa
    34381 aaggcgctag aggatgctgg agcaacggtt tatttgaccc atactacaga tgaattagta
    34441 cagcttggag atatatgcga ctacagtgaa gaaaaaaagg cagatgtctt tatcagttta
    34501 cacgcagact ctacggaata tgcgaatgaa gcaactggaa tcacgacata ttattactat
    34561 ggacaagagg aaacattagc acagacaatt gctgactcct tcactgatct gcctctggat
    34621 tcaagaggaa tctccactgg gaactatcaa gttcttcgag aaaatcttca accttctatt
    34681 ttaatcgaga tgggttatat gaataatgat agtgatttaa aggaattagt aacagacagt
    34741 tatcagcagc agattgctgc aagtttgaca caagcattga ccacttattt tcagtaataa
    34801 ataagcccag ccaaacaaaa atagctcctc atatttttcg tttggccggg cttattatcg
    34861 cagatgcaag cttttgaaca ccgtttaagg aagaggttgt gagcctgccg tttaactccg
    34921 cgtcacaagg agcaatttca aaaaacagct tctcatgttt gatgactatt gtgacttgtg
    34981 accgaggagt tggcatgaga acaccgttta ttcggaacaa gggactgtga catgactttt
    35041 gtcacagttc cattattttt ttagcagctt caaagctttt tctgtattgg caaaatgaag
    35101 tttggcatat ttttcaagca taggcatgcc gcctttctcc aatagttttg ccgctacttg
    35161 gtcagatttc gttccagctc ctgatggaag ggtgattcca gcttcagctg atgctttgtg
    35221 taactcttcc aaaaagctgg cacgactgat gatagaagca gcagcaacag ctaaatgata
    35281 ttgttctcct ttagtaacga agtacagttt ttcttgtaat tgattttttt ctaaacgcgc
    35341 atatttttta aaatttgctt ccggcgtaaa ctgatcgatc aaaatcgctt ctggtttttc
    35401 tggctcgatt ttttttagca gcaaatggat cgcttgattg tgcaaagcga ctttcatccg
    35461 aacggcattg tattttggtt ggatctcatt gtatttttct ggagataaga caagcagttt
    35521 ataggggatg gtttttttta agatgtcagc aagctggatg atttggctat cttttaactc
    35581 ttttgaatct ctaacaccaa gtttacgtaa ttctgcaagc tgatcacgtt tcacataagc
    35641 agcacatact gttagcggac caaaatagct gccatttccg acctcatcac tacctaaaac
    35701 ggataattga ctgatatttt ttggcaaaga agaggctgtt tttgctggct tggcttgttt
    35761 atcctgtgcc tccccccatt tatcagcttc tattgctgca ttcgtacctt gaaacatcac
    35821 ttttccggat gtataagcgg taatggtcgt cccgtctttt tttgcagcaa agctagtata
    35881 aggaatctgt ttatttaaca aataagagcg atagtatgct ttcatttgac taagttggtc
    35941 gtttgttgct ttgataatga cgttgctcat aaaattctcc tcgtttttat acataaaact
    36001 ataccgcaac tcacgacttt tcgttttcta agagattgcg agacatagca tttttttaaa
    36061 gtttatcata taatagttaa gtatgtgaaa aatatttgtg gagaacggtg aaagaaccaa
    36121 cttcatggta cactaaataa aactttcatc aaataggagg aaatgattcg tatggcgcac
    36181 gaaaaaacac gctacaaagc agtgattgcc aaccaaacat atactattat cggacgggaa
    36241 accaagcatc atatggatat cgtaacgaag ctgatcaatg aacagttagc agaattgaaa
    36301 caattatcac cacaaatgga taatgaacaa gcagcaatct tgatggctgt caatgcgctt
    36361 tcggatcaat tgaagaaaca agaaagaatc ttggagctgg aagaagaaac agcagaatta
    36421 aagaaaaaaa tgatcaaatt tacagagctt gaaaatcgtg tgaaacgcat tgaagcaatc
    36481 gagaacgaag ctcgggaagt attgaaagaa aatggtcaag cagatcatac cattaaaaat
    36541 catgtggaag cacaacagat tttaaacgag aaacgaaaag gacaaattaa acaaaaatct
    36601 tctaattaag atccttttat caaaataaga aaaatttaaa aaagttagaa gagaaaggaa
    36661 cgtagcatgc tgagtttgct gattttattt ttattgctaa ttgcgttttt ttctggagca
    36721 cgtcgcgggt ttgctttgca aatcatattc gcgattggat atgtattgtc atttattgct
    36781 gcccagcatt tttacaaacc attagcaagt catttggaat tatacattcc atacccagct
    36841 gtcaccccaa catcaaagtt agcatttttt gatcaggtat ttgcttttca cctagatgaa
    36901 gctttttatg caggaactgc ttttctgatt attttgctaa ttggctggct gcttacccga
    36961 tttgtggggg tttttgtcca tggattgacg tatgtgccga tcttgagaca ggtagactgg
    37021 attgcaggag gcatcctgtc actaatcatg gcttacgtta ctatattttt gattttgcag
    37081 ttacttgcct ttgttccatt agatgtggtc caaaatcaat tcggcgagca tagtttcgct
    37141 cgttttatcg ttgagagaac gccatttctt accaacaaga tgtatgagct ttggtaacga
    37201 atattttgaa ttaaggaaaa tagtgctgga aaatatttcg ttttttgtac agagtagttt
    37261 atttaagaag gctgcgtagc gtatgtccgg cacagctctt ttttcatagt gaaagataag
    37321 gtgataaaat gaataaccga atccttgaaa cattggaatt tgaaaaagtc aaacagatgg
    37381 tcagacaatt tgtagtgact gcacaaggaa aagaagaact ggcagaattg gtaccagtga
    37441 gtgagaaaca aacgatcaca aactggcttc aagaaactga ggatggattg aaagtgcaac
    37501 gtctgcgagg cgggatccct atacctaaac ttgaaaatat ccgtccccat atgaaacgga
    37561 tcgagatcgg agcagacttg aatggagtgg agcttgcaca agtttccaga gtattgtcta
    37621 cgacaagcga attgaatcgt ttcattgatg atctttctga cagtgaaatc gaatttgcac
    37681 gtttgtatat gtgggcagat cagttagtca cgatccctgt tttgagccgc cgtttaaagg
    37741 aagcaatcga tgaagacgga cgcgtgactg atgacgcttc tcctgagtta aagagcataa
    37801 gacagaacat tcggcgaagt gaacaagctg ttcgtgaaca gttagatggg atcgtccgtg
    37861 ggaaaaatgc aaagtattta agtgatgcga tcatcaccat gcgaaatgac cgctacgtta
    37921 tcccagtcaa acaagaatac cgcggtgtat ttggcggtgt agtccacgat caaagtgctt
    37981 caggacagac tttatttatt gaaccaaaac aagtggtgga tttgaataat cgtttgcgtc
    38041 aataccaaat cgctgaacga aatgagattc aacgtatttt aagtgaactt tctgctgaac
    38101 ttgttcccca tcgtcaagaa atcatccaca atgcttatgt gattggtaaa atggatctga
    38161 tgaatgcaaa agcacgattt ggtaaagaag taaaagccat cgtgccggga atcagtgaag
    38221 acaatcatgt cgtcttgaaa caagcaagac atccactgat cgatcaggaa aaagtagttt
    38281 ctaatgacat cacaatcgga aaagactatc aagccatcgt cattacagga cctaacacag
    38341 gtgggaaaac gatcacgttg aagactttag gtctgttaca actgatgggg caagcaggat
    38401 taccgattcc tgcaggtgaa gaaagtcaaa tcggtatttt tgaggaagta tttgcggata
    38461 taggagacga acagtcgatt gagcaaagtc tatcgacctt ttcttctcat atgacgaaca
    38521 ctgtagatat tttatcaaaa gtcaatgaaa aaagtctggt attatttgac gagctcggtg
    38581 caggaacaga tccgcaagaa ggtgctgctc tagcaatcgc aatcttagat gatcttggta
    38641 aaaagtctgc ttatgtgatg gcaacaacgc attatcctga attgaaagtt tatggataca
    38701 atcgggcaaa tacgattaat gccagcatgg agttcgatgt ggatacacta agtccaacgt
    38761 atcgtttgct gattggcgtt cctggacgaa gcaatgcgtt tgaaatctct agccgattag
    38821 gtcttgatac agaagttatt gatgaagcga agcagttgat gaatgatgag agccaagatt
    38881 taaacgaaat gatcacagat ttagagaatc gccggaaaat ggcagagacc gaatatctgg
    38941 aaatgcgtca ttttgtttct gaggcacaag aacttcacga tgatttgaaa gaagcttaca
    39001 gctatttctt tgaagaacgt gaaaaagaaa tggaaaaagc aaagaaaaaa gcaaacgaag
    39061 tcgtgtcaga ggcggaagaa aaagcagaaa aaatcattgc tgatattcgt aaaatgcaac
    39121 agcagattgg gcaaggaaat gtgaaagagc atcagttgat cgatgcaaag acccaattag
    39181 caaatctaca tcaagaagaa actttgaaga aaaataaagt attgaagaag gcgaaagaac
    39241 aaaaaacgtt gaaaccggga gacgaagtgt tggttacgac ttacggccaa agagggacgc
    39301 ttttacgtaa aaacgggaat cagtggcaag tagaaatcgg tatattaaaa atgaatgtgt
    39361 ccgaagacga gctgacgcct gttgctcctc aaaaagagcc gacacaacga gttatccatg
    39421 ctgtacgatc tgaatctagt agtcacgtgc cgaatcaatt ggaccttcga ggaaaacgat
    39481 acgaagaagc gctaagtgag gtagatcaat atttggattc tgccattcta gctggttatc
    39541 ctcaagtgac tattgtccac ggaaaaggaa caggcgcact tcgcaaggga attactgatt
    39601 atcttaaaaa ccatcggagc gtcaaaagct ttgagtttgc accggcaaac caaggcggaa
    39661 atggtgcgac aattgttaaa tttaagtaaa gcttactaaa ggtaagcaga tggttcgcta
    39721 tccaagtata gaaatgctat actaatcata gattttaaaa atggaggtct ttgatatgtc
    39781 acaagtaatt acagataaga catttaatga agaaacagat aaaggacttg tattgattga
    39841 tttttgggca acttggtgtg gtccatgtcg tatgcaagca ccgattttgg atcagttgga
    39901 acaagaatat gatgaagaag aattcagaat tgctaaaatg gatgtggatg aaaatccaga
    39961 aactcctcaa caattcggta tcatgagcat tccaacatta atgttgaaaa aagatggtca
    40021 agtagtagaa aaagctgttg gtgttcattc aaaagaacaa ctacgtcaaa tgatcgatca
    40081 atatttataa aaacttacag caaaaataag ctgagggtgg gactgaatcc agttccgtcc
    40141 tcggtttttt tgcggttgag ttaaggttat tcaaattaat attttttgag tataattacg
    40201 ttgtcaggct ggattgtttt tttgacagac atgctataat aactttaatt gaatatgaag
    40261 gggagtacca gatgaacgaa cgaatcaaaa acaaattagc tttacttcct gatcagcccg
    40321 gctgttactt gatgaaagat aaaaatggaa cgatcattta tgtcggcaaa gccaaaatat
    40381 taaaaaatcg tgtccgctca tattttactg gcagccataa tacgaaaacg gaacggcttg
    40441 ttagtgaaat cgaagacttt gaatacatcg ttacagaatc gaatatcgaa gcattgctct
    40501 tagagatcaa tctgataaag aaaaatgatc ctaaatacaa cattatgtta aaggatgata
    40561 aaacctatcc tttccttaag ataacgaatg aaaaatatcc ccgtttggtg attactcgta
    40621 aagtactaaa agacaaagca ctgtattttg gaccatatcc cgatgtcggt gcggcgaatg
    40681 agacaaagaa gatcctcgat cgattatttc ctctgagaaa atgcaaacct agtcagacga
    40741 aggagccttg tctttactat catttgggac aatgtctgtg tccttattat ttcgacgtag
    40801 atccgaaagt ctatacgaaa atcgttgatg aagtgaaaaa gtttttaaac ggaggacacg
    40861 aaaaaatcga gtcagagatc catcagaaaa tggaaaaagc tgctgaaaac atggagtttg
    40921 aaaaagctgc agaataccga gaccagatcc gtgccattga gacaatcatg actcgccaaa
    40981 aaatgacaaa tactgattta ctggatcgag atgtatttgg ttatgcgatt gacaaaggat
    41041 ggatgtgtgt ccaagtgttt ttcgtaagac aaggaaagct aattgaacga gatgtttcaa
    41101 tgtttccttt ctataacgaa gcagaagaag atttcttgac ttacctcggt cagttttatc
    41161 aggaaaatga gcatttcatt cctaaagaag tcttgattcc tgatacgatc gacaagccca
    41221 gtgtagaagc tttgttagct acgaaagtgc tgcaaccaaa acgaggagaa aagaaaaaat
    41281 tagttgaatt ggcgaataag aatgcctcag ttgctttgaa tgaacggttt gatctgattg
    41341 ccagaaaaca ggaacggacg atcggagcag ttgaacgttt aggaaacgcg atgaatatcc
    41401 cgaccccaat acgtatcgag tcttttgata actctaatat catggggacg aatcctgtgg
    41461 ctgcgatggt cgtattcatt gatggaaaac cggcaagaaa agaatatcgg aaatataaaa
    41521 taaaaacagt caacggaccg gatgattatg catcaatgag agaagtcatc tatcgcagat
    41581 attcacgagt gattcgcgaa gggttgcctt tacctgattt gatcttgatc gatggaggaa
    41641 aaggacaagt agatgtggca aaagatgtct tagaaaatca attaggaatc gatattccta
    41701 ttgctggcat ggcaaaaaac gataaacata aaacaaatga gttgctattc ggtatagatt
    41761 tggctgtagt accgcttgag cgaaattcac cagagttttt cttactccag cgaatccaag
    41821 atgaagtcca tcgattcgca atcactttcc atcggcagct acgcagtaaa aacagttttg
    41881 cttcccgatt agatgaaatt gaagggttag gaccaaaacg aaaaaaaatg ctgcttaaag
    41941 agttcaaatc gttgaaaaat atcacagcag ccacgacaga agaattacaa gaaatcggac
    42001 tgccgaaaaa tgtcgcacaa aacgtatttg ataaattaca tcaggaatga ggaaagggca
    42061 ctttacaaag aaagtaaagt gtcctatcat tttatgtaca acaaaaagag cgtttacgtt
    42121 ttgttggtaa ataataaatc gcttacgtct ggtgtctaag gatatatgtg atttcttgaa
    42181 gaaggagtga agaaatgtta gaagtcaagg atcttgttaa aacttttggg aactacacag
    42241 ctgtcgatca tgtctctttc caaatccccg atggaaaaat catggggcta attggccaaa
    42301 acggggctgg gaagacaacg acttttcgtt tgatcttgga ttttttgaca caagaccaag
    42361 gagaagtgtt atggaatggc catcatcttg gggagaaaga ttatgatgtc atcggttatc
    42421 ttccggagga acggggactt tatccgaaag taacgattca agaccaactg ctttattttg
    42481 cagaacttag agggaaatca agaaaagaga ttgaaccaaa aatcgatttt tggatggaaa
    42541 aatttcaggt aaaagggaaa aagacggata aagtaaaatc tttgtctaaa ggaaatcagc
    42601 aaaaagtcca gctgatcgcc acgttaatcc atgaacctaa attgatcatt ttggatgagc
    42661 cattcagcgg gttagatccg gtaaatgctg aattgctaaa agatggaata ttggaattga
    42721 aaaaacatgg ttcatgtgtc attttttcta gccacaatat ggataatgta gaaaaaatct
    42781 gcgatcattt gatcatgttg cgaaacggaa aaatggtttt gaatggaaaa gtacatgaga
    42841 ttcgtgaatc atttggccgt acgaagttat tcttggaatc tggtttaagc caacaggaag
    42901 tagaagaaat cgaaggcgtg aaaaaagtga tccttcatga agacaatacg ttagagatta
    42961 ccttagaaga tcctgaagct gggaaagaaa tctttactcg tgcgactcag ttcggctaca
    43021 ttcctatgtt taaccagcaa ccgccaactt tggaagagat tttcaaattg aaagcaggtg
    43081 aaatcgatgc gtaagttttg gattattacc aaagatgtct atttaaaaaa tgttaagtcg
    43141 atttctttct tgatcatgat attagtccct tttatcatgc tgggtatcat ttatgtagca
    43201 ggaaactttg ctcaacaaaa tagtgatgtc aataaaatcg gcgtattggc tgataatgag
    43261 caaatcagtc agcaaatgag ccaagtcaaa acagatgatt ttgagttcaa agcagttgat
    43321 tctgaagaaa aagcacaaaa agagctttcg gaagaaaaaa tcgatgcgta tttagtagtc
    43381 tcaactgaga atgataagat aaatgggatg ctttatagcg aaaattcatt aggacaaagt
    43441 acacaactac tgatacaaca acaactgact ggcttgcaat cgatgcttcg agcaagtcaa
    43501 ttaggcattt caccagaaga agtagctagc ttgagccaac aagcaagttt gactcgacaa
    43561 aaagtcaatt ttgattcaaa aggaaaaatg acagttggag aagataactc gacagtccaa
    43621 tatgtcgtaa gttatgtagc aacgattgtc ttgttcatta ttattttgac gtatgcgcag
    43681 atcattgcac aagagatcgc ttctgaaaaa ggcacgcgga tcatggaagt gatcctgtcc
    43741 agtacgactg cacaaaagca tttttacgga aaactaacag gtgttttact tgttgcatta
    43801 acgcaaatgg cattatacgg tattattttt ggtataggat acagtcaatt caaagatatg
    43861 gaaatggtca aaaatatatt agacggtatc tcattggata acttgattgg accattcttg
    43921 tggtattctc ttctattcat gatctttggc attttgattt tttctgtttt agcagcttta
    43981 tgtggctctt tggtcaacaa agcagaagat acagcaaaag caattttgcc agtgacttat
    44041 ctatctctag gcggatatat gcttggattg atactaggag cttcagatcc aaacaatatc
    44101 gttattcgga tcacttcgta tattccattc ttatcttcat atattatgcc ggttcgctta
    44161 gcaaatgaga cagtcggtat gggtggagca ttgatttcct tgttggtact tgtagccgta
    44221 acattcttat tgatgatctt gtctgcaaac atgtacaaat cgaatgtact cgtgtatagc
    44281 gaaggcggat tatggagttc attgaaacaa tcgatttcaa ttatgagaaa tgaacgaaaa
    44341 aaagcataaa atatagaaaa atatagaagg aagctggaca tttattgttc ccagcttctt
    44401 ttttgtatag acctatttct atttttttat tatattggat atatatattc attgaaaata
    44461 gagcataaca actttataat gttgagtata ccaatttttg gaggcgtttt aatggaccgc
    44521 tatttagatt tactttcaga gaagttccct acaacggaag atgtcatcac ggaaatcatc
    44581 aatctcgaag caattttgca gcttccaaaa ggaacagagt tatttttgag cgatatacat
    44641 ggcgaatttc ctgcttttga tcatattctg cgtatcggtt caggaaatct taaagaaaag
    44701 atcaaagacc ttttctctga acaaatgacg gaaacggaga tcagccaatt cactattttt
    44761 acggcttatc cagaatatgt gttgacgact gattggtaca aaaaacaaga taaatcccag
    44821 ctgatccatc gtttgatcga tcttttacgg tttacgacag tcaaatacac tcgatcaaaa
    44881 gttcgaaaag gattgccgaa agaatatagc tatatcattg aggaactctt gtatatcgat
    44941 gatcgtatca acgggaaaaa agactatgta aaaaaaatca ttgaacaact tgtcttgatg
    45001 aaggaagaag aaaaattttt aacaaaactt gcgcagacga tccaaaaatc tgtcatcgat
    45061 catttgcata tcgtgggtga tatttttgat cgaggaactc aagcagccaa agtaatggat
    45121 cgaatcatgg atttttcctc tgtagatatc cagtggggga atcatgatat tttgtggatt
    45181 ggtgcgtatt gcggctctga ggcatgttta ttgacgcttt tacggattgc cgcacgctac
    45241 aactatttat ttgaattaga gaaagaatat ggattaaatt tacgtccatt attttctttt
    45301 gcccatcaaa cctatcagaa gaatccagta tttaccccta aaaacaggaa agatctatct
    45361 gaaagagagc aagaagaatt agaaaagatc catcaagcac tttctatcct ccaattcaaa
    45421 tcagaacatc agttgttgaa tcgacgacct gaatttaaaa tggacgatcg taaattgttg
    45481 gaaaaaatca actatgagga atcaacgatc gttttagaag gtcagctcta tgagttgaaa
    45541 gggacttgtt ttcaaacgat ccagccagat gatcctaaaa aattcttgga agaggaacaa
    45601 aaagtgatcg atagtttgat gtattcattc cagcactcgt taagaatgca aaaacacatg
    45661 acgtttttga tcgaaaaagg gggaatgtat ctcacgaaca atcagcatgt actgttccat
    45721 ggctgtatac ctgtagatga aaaggggcag ctcttagcat ttgaattaga ccaatcttat
    45781 cgcggaaaag aactgctggg attttttgaa aaacagataa ctgaaagcgc aaaagatttg
    45841 actgcaaatg aagatttggc gaccgatttg atttggtatg cgtggagcgg gccattttcg
    45901 cctttattcg gcaagagtaa aatggcaact tttgagcgct attttctcac agagcctcat
    45961 acgcacgtcg aaaaaagcaa tccctattat cacttgcgag atgaagagtg gttcagtgaa
    46021 aaaattttgg cagaattcga tgcaaaagaa gaaggttcag caatcatcaa tggacacacg
    46081 ccagtaaaag taaaaaaagg agagtcaccg atcaaagcaa acggaaaagc atttgttatt
    46141 gacggaggtc tatccaaagc ttatcaaaaa acaaccggga ttgctggcta ctcattacta
    46201 tgcaattctt acggtttcca aatcgtgaca cattatccgt tcttgcctat tgaacaacaa
    46261 tttgcaaaaa aatctgatca aacgaatgta aaaaaagtga tcgagcagca gctcccacgc
    46321 aaacttaatc ggaatacgac aaaaggaatg gaattacagc aacagattac tcaactccaa
    46381 aggctgttgg attatcgaaa ggacgattga gaaaaatgct agccaacatt gctcaataga
    46441 ctaaaaagcg actgcaacaa aaggcgtgtc gcagtctcct tcggaattag ctcaaaaaac
    46501 ggtaaaatat tagaagctat ttttctgttt atttctctaa tactcaggtc agggcgctga
    46561 tttcacgacc tcttccttaa acggtgttct cctgccaact cctcggtcac aagtcacaat
    46621 atccaacaaa catgagaagc tgttttttga aattgctcct tgtgactcag agttgaacgg
    46681 caggctcacg acctaatcag aaaaacgatt aaaattcatt cacaaagaaa tcgaataaac
    46741 gctgttcaga tgaatctaca cgatgagaaa gttccggatg ccattggaca ccaaggattt
    46801 tgtgcatatt atctttactt tggactgctt caatgagtcc atcgttggaa aaggcgatgg
    46861 cttttaacaa aggagaaaga tctttgactg cctgatgatg ataggaattc acaaagtatg
    46921 aatcagggag aaggtcactt aataaactgt ccgaaacgat tttgacttcg tgagttgcaa
    46981 actgcggggc agtgggctgt tgttcgtgtt ttacggacca ttttggatat aatgaaagat
    47041 cttgataaag tgttccctcc aacacgacat tcaatagttg aagtcctcgg cagactgcaa
    47101 aaatcggttt tctttgtttc aatgcttcca agatcaatgc ctgttcgaat tggtctcgtt
    47161 gaatatttgt ttccgtcagt tttggatgag ggtcttccat gtaaagttgc ggactaacat
    47221 cctgaccgcc tgcaagaatg agtttgtcga ttttctcaat tagttgaggc gctgaatctg
    47281 gagacatgac tggcagaata agaggtaatc cttgagcatc taaaactgca tccacaaatc
    47341 cctgcggtgt atagcttact tgatttcctt ggaaagtatc tgtcgctcga atcagttgat
    47401 tcccggcaat gccgatgatt ggtttcattt ttattccccc taaagtagac taattgtaac
    47461 aaggatttaa aaaaatttaa actatgtaag acttgcccct atacttatct gttcttgctg
    47521 tgttactatc tgtaaagaga attttcgtgt gaaattcatg acgatagttg aaaatattgc
    47581 ttaatttgtt ataataaaaa gtaagcagaa ataaaaaggt tgggcgtaag cttcaaggat
    47641 ctagttcttc aaggggtgag aaggacattt tattgaaggg gcctgcctat actaagttat
    47701 ctttagaggt acatactttc aatgaaaaaa gaaagcatgt acctcttttt taaatcgaaa
    47761 ggaagtgaag caagtgttag aagctttgga acaaatccga aaagcagaag aagaaaatga
    47821 gaagcgtgct cgaaccctac ggcagcagtt gaagacctat gcagaagaaa aagagcaaga
    47881 attggagata atccaaacga acagtcggca acagctgaaa cagttggtag aagaaaaaga
    47941 acaattcgaa aagcaagaat tagaaaaaga aaaaatgaaa ttgaaagcag aagcagacaa
    48001 ggtgcaagca actttgaaag accaatatca aaagcatcag agtcaagcaa tcggtgcaat
    48061 cattgaaagg gtgaaagaaa cttatggccg tcactaagat ggaaaaagtg accctcattt
    48121 cagataaaag aaatcaggag aggattttac aagcagtaca aggaatccaa aatgttgaaa
    48181 tccgggatct gtatcaaaat agaacaaaca accagtgggt agaaaaatat tttccagata
    48241 ccacgattat tgataaagaa gcaaaattaa gcgctttagg caatcggctg aaagacatcc
    48301 aagaagctat ccaattcata caacaccacg gcgatagccg tcaaaagaaa ctccatttga
    48361 aacgtcaaga actttcctta caagacttgg aagcaaatta ttccgaagaa aatttcatga
    48421 ataaattaga agaagtcctt gatttaaaag aaaagtggga acagctaact gaaaaacgtg
    48481 atcgtttaga agaagaggaa gaatggcttc ttcattggca acagctggat attgctccaa
    48541 gtatgtatgc aagtaagacg accatttttg agatggggac tgtgagtgca gcaaattttg
    48601 aaagtttcaa ggaagaacta agtaagcttg atgacgttta tatggaagaa atagattata
    48661 cgccaaaaca agtttatctt tcgtatgttg ctttaaaaaa atcagttgct gctatagaag
    48721 aaattgctgg gaaatacggg ttcaataaag aaacgtatcc ttatgaacaa aatcctaaag
    48781 aaaaattgca agaaaccaaa cagcaattat ccattgttca cgagcagcaa aaaaagataa
    48841 cgacagcgtt aggtcagtgc agcggctata tccaagaatt tgaatgggta gaagaagtca
    48901 cacttgccgt tgcagaacgg gaaaaagtaa aagaacggtt tatccatgcc acttatctga
    48961 tcgttttgca aggttgggta gatgcagaag aaaaacagaa tttgatgcat gtgttaaacg
    49021 aaactgtatc agaagaagat atatacgtta gtttcgaaac accaaactca gaagagattc
    49081 agcaggaagt ccctactaaa ttgaaaaacc atccgcttat cgaacctttt gaattgctga
    49141 ctgaaatgta cagtctgcca aaatatgaag aagtagatcc aacgccttgg atgacaccat
    49201 tttatcttgt cttcttcggg atgatggtcg cagatgttgg ttacggattg ctgatgctca
    49261 ttgggacaat actagctcaa aaactatttg ttttaccccg cgggatgaaa cgtttcgtaa
    49321 aattctttga gattctctcg gtaccatcga tcatctgggg attgatctac agttcatttt
    49381 tcggacaggc attaccaaaa gaactatttg gtatccgctt gcctttccca atcctatcta
    49441 cgacggatga cgtcaatacg attttgattt tatccgtgat tttcggtctg atacagatct
    49501 tggttggatt attcgtggca gcaaaggaaa atatcaggag gaaagattac ttgagtgctg
    49561 tcagtgatgg ttttgcctgg caagggatcc tgattgggat cgttattgca ttgattggtg
    49621 tcatgttgat aaaaaataca gcatttgttt atcttggcgc ggggctatcg atcattgctg
    49681 ctttatgtat cttaatcgtg ccgattatcc aatcgccgtc taaagtcaag ggtgctgcca
    49741 aaggagcgta taatctttac ggattgactg gttatatcgg tgatttagtc agttatacac
    49801 gtttgatggc actaggtatt tcaggcggaa gtattggcgc ggcattcaat atgctagttg
    49861 ctttcatgcc gccagccgct cgattcagtg tagggatcct tttgatcatc gctttacacg
    49921 cactgaatat gtttttgaca ctgttaagtg cctatgtcca tggtgcacga ttgcagtatg
    49981 tcgaattttt tggaaaattt tatacaggag gcggacgtgc ctttgacccg ctgaaaacgg
    50041 cggaaaaata cgtcaacatc aatcataaga aaaaaaacaa taaataattg gaggattttt
    50101 atacaatgat ggattactta attagtcaaa atggtggaat ggtatttgca gtattagcga
    50161 tggcaacagc gacgattttt tcagggattg gttcagctaa aggtgttgga atgacaggtg
    50221 aggcagcagc agcgttaaca acaagtcaac ccgaaaaatt cggacaggct ttgattctgc
    50281 aattgcttcc aggtacgcaa gggttgtatg gattcgttat cgcctttttg atttttatca
    50341 acttaggaaa tgatatgtca gttgtacaag gattgaactt tctaggcgct tctctgccga
    50401 ttgcttttac aggtttgttt tcaggtatcg cccaagggaa agttgcagca gcaggtatcc
    50461 aaattttagc gaaaaaacct gaacatgcta caaaaggaat catttttgct gcgatggttg
    50521 aaacatatgc gattttaggt ttcgttattt ccttcctatt agtattgaat gcctaagcat
    50581 aaaggaggaa aagcagatga acgccattga aaaaatcatc tctcagatga atgaagcagc
    50641 agagcaagaa agagcggcgt tagagcaaga agagcgaatg aagatcgatc aaaactttga
    50701 acaaaaacgt acgcaaatcg aaacagaaca tcaaaaacaa aaagaaaaac aaatcgaatt
    50761 acttgaaaaa aaataccgtc agcttaggaa tcgccaacaa gtagaagtac gacaagaaaa
    50821 tttgaatgcg aagcaggaat ttttacgacg attgtttgca gatgcaatag ctgaaatgga
    50881 gaattgggat gaatctgaac aaatccagtt tatcaaaaat tcattgtatt cattaccttt
    50941 gacaggcaaa gtaacattca ttgctggaga aaaatcagca gcttatcttt ctcagacatt
    51001 gctggatgaa tggaacaatg aacttccctt tatgatggtt ttaagtgatg aaactgttgc
    51061 tgatcaagcg ggttttctga taaacgatca aggagttcag tataattttc ttttcagcag
    51121 ccttgtacaa gatatccaag gaacgatgag ttttgagatt gccaatcaat tattcgaata
    51181 aggagggatc agtgtatgga ataccacgaa ctaaatccct tgattcgcgg aagagagctt
    51241 gaacttttgt ccaatgagac atttgaacgg atgattcaaa caaattctgt cgaagcactt
    51301 ggtgaaatat tgaaatccac gatttacagt ccatatattt atgacggata tgaatatgac
    51361 ttcgaacaga atcttttaaa ggagcagagc cgtctatttc gctggttaaa ggaatcagca
    51421 ccggagcctg aaatcgtttg gatctatacg atgcgctata ctttccataa tctgaaggtt
    51481 ttgacaaaag ccgagatgac aaatcaaaat ctggaccatt tgtatatcga cgatggattt
    51541 tattcattag aaaccttgaa ggatgccatt catacgcaag tttcaaatga actccctgaa
    51601 agcattatgg acagtatacg agaagtacgt gattattttg aagagtctac cattcttcag
    51661 ggaattgacg tgatttatga tcgacagttt ttgacagagc agcgacggct tgccgataag
    51721 ctaggatatc aagaattgct gacagaagtc attgctttta ttgacttgac caatatcaca
    51781 acgatggctc gaggaatatt gcagaaaaga acatatgggt tcatgacgac ggtactttcc
    51841 agctcgggaa gtatcgaaaa agaagtattt ttgaactttg tagataaaga tatggaagat
    51901 tacacgaatt ttctattaga gacagattat gctgattttc tgcgccctgt catccgtgag
    51961 ggaaatcttg atctcgtaaa gcttgaacag ttgaaagatg attatctaag ttcattgtat
    52021 caagaagcac aaacccaggc tttcggacca ctgccactac tagccttttt gaacgcaaaa
    52081 gaggtagaaa gcaaaaacct tcgtttactg gttatcggca aaagaagcca tttcgaacca
    52141 gaaacaatca gaaagcgggt gagacaagtc tatgacgcat aagatcggtg tagttggcga
    52201 caaagattct gttttgccat tcaaattgtt tggctttgat gttcgttatg gtacaaccaa
    52261 gcaaaccgtt cgtcaggcaa ttgaagaaat ggcaaagaat gagtatggcg tgatttatgt
    52321 cacagagcaa tgtgcagcat tgagcccaga aacgatcgaa cgttacaagg aacaaatgat
    52381 acctgctatc gtattgattc ccaatcatca aggatcatta gggatagggc tggaagaaat
    52441 tcaaaaaaac gtagaaaaag cagtaggtca aaatatctta tagtatgaaa aggagataga
    52501 aattttgcaa attggaaaaa tcataaaagt ctccggacct cttgtaatgg ctgagaacat
    52561 gtctgatgcc agtatccaag acatgtgtct agtgggagat ctaggagtta tcggagaaat
    52621 tatcgagatg cgtggcgatg tggcgtctat tcaagtatat gaagagactt ctggaattgg
    52681 tccaggcgaa ccggttcgct ctactggtga agctttatct gttgaattag gaccagggat
    52741 catttcacaa atgtttgacg gaatccaacg gccattagat acctttatgg aaatcacaca
    52801 aagtaatttc ttagggcgcg gagttcaatt gcccgcattg gaccatgaga aaaaatggtg
    52861 gttcgaacca acagtagaag ccggagaaac ggtgagtgct ggagatgtta tcgggatcgt
    52921 agaagaaaca aaagttataa aacataaaat catggtgcca aatgggataa aaggaacgat
    52981 caaaacaatc gaaaaaggtt cattcactat tgatgaaaca gtatgtgtca ttgaaaccga
    53041 aaatggtgac aaaaatttga cgatgcttca aaaatggcca gtaagacgta gtcggccaat
    53101 caaagaaaaa ttaaacccgg atgcacccat gatcactgga cagcgagtga ttgatacatt
    53161 cttcccagtg acaaaaggag gagcagcagc tgtacctggt ccttttggtg cagggaaaac
    53221 agtcgttcag catcaaattg caaaatgggc cgatgtggac atggttgtct atgtgggatg
    53281 tggcgagcgt ggaaatgaga tgacggatgt tttaaatgaa ttccctgaat tgattgaccc
    53341 taatacagga gaatcgttga tggaacgtac ggtattgatt gctaatacat caaacatgcc
    53401 agtagcagct cgagaagctt ctatctatac gggaatcaca attgcggaat atttccgtga
    53461 catgggttat gacgttgcta tcatggcaga ctccacttca cgatgggcag aagcacttcg
    53521 tgagatgagc ggacgtttgg aagaaatgcc tggtgatgaa ggttatccag cttatcttgg
    53581 ttcacggctt gcggaatact atgaacgatc tggaagagtc attgcattag gatcagaagg
    53641 tcgcgaagga agtataaccg caatcagtgc tgtatccccg tctggagggg atatttcgga
    53701 accagtcaca caaaatacat tgcgggtcgt aaaagtattc tggggtcttg attccagttt
    53761 agcccaaaaa agacattttc cttcgatcga ttggatacaa agctattctc tttattcaac
    53821 agaagtaggg aagtatatgg atcatatcct tcaagctgac tgggcatcca tggtcaccga
    53881 gggcatgcgt attttgcagg aagaacagca gctgaatgaa atcgtgcgtt tggtagggat
    53941 tgattccctt tcagataatg accgtctgac attagaagtg gcaaaatcca ttcgtgaaga
    54001 ttatttgcag caaaatgctt ttgatgatgt cgatacattc acttcaagag agaaacaatt
    54061 caaaatgttg aagatgatct tgacctttgg tgaagaagga cgccgtgcgt tgtcgttagg
    54121 tgcttattta agtgagatca tggacggtac cgtatcgatt cgtgaaagga tcggacgaag
    54181 caaatatatc ccggaaacag aattagaaaa actagatcaa attattggtg aaatcaagca
    54241 aacgatgcaa acgatcgttt cagaaggagg catgagcaat gattaaagaa tatcgtacga
    54301 tcggtgaagt cgtcggtcca ttgatggcgg ttgaaaaagt tgctggtgtc aaatatgaag
    54361 aattaatcga agtccgtatg caaaatggcg agattcgtcg tggacaagta ttggaagtcc
    54421 aagaagataa agcaatggtc caaatattcg aaggaacaag tggtatcaat ttacgtgact
    54481 cttctgtacg atttttaggc catcctttag aactaggtgt atcggaagac atgatcggtc
    54541 gagtattcga tggtttggga cgaccgaaag ataacggacc agagatcctg cctgaaaagc
    54601 atttggatat taacggagaa gtaatcaatc cagtagctcg ggattatcca gatgagttta
    54661 tccaaacagg tatctctgca atcgatcatt tgaatacatt agttcgtggg caaaaattac
    54721 cagtattttc tggctctggt cttcctcata aagaattagc tgctcagatc gcgcgacaag
    54781 caacggtact cgattcatca gatgatttcg ccgtagtctt tgctgctatt ggaatcactt
    54841 ttgaagaagc tgaatttttc atggaagatt ttcgtcaaac gggcgcaatc gaccgttctg
    54901 tcatgtttat gaatttagca aacgaccctg caatcgaacg tatcgctact cctcgtatgg
    54961 ctttgactgc tgcagaatat cttgcttatg aaaagggaat gcatgttttg gttatcatga
    55021 cagacatgac caactatgca gaggcattgc gagagatttc tgcagcacgg cgagaagttc
    55081 caggaagaag aggatatcct gggtatcttt acacgaactt agctacttta ttcgaacgag
    55141 caggaagaat ccgcggacta aaaggatcgg ttactcaaat tccgattcta acaatgccag
    55201 aagacgataa aactcatcca atccctgact tgactggtta tattacagaa ggacagatca
    55261 tcttgactag agagctttac aagagtggga ttcagccacc aattgatgta ctcccgtctc
    55321 tttcgcggtt aaaagataag ggaactggac ccggaaagac aagagaagac catgcagcta
    55381 cgatgaatca gctttttgca gcctatgcac aaggaaaaca ggcaaaagaa ttagccgtag
    55441 ttttaggtga atctgcttta tctgatgtag acaagatcta tgcgaagttt gctgagcggt
    55501 ttgaaaaaga atatgtcaat caaggattct acacgaaccg ttcgattact gaaacacttg
    55561 atctagggtg ggaactgcta tcgatgttgc caagaaccga attaaaacga atcaaagacg
    55621 acatgctgga caaatatctg ccagaaggga agtgagttct gatggcacga ttgaatgtga
    55681 atccgacccg catggaattg actcgattga aaaaacagtt gacaactgcc acaagagggc
    55741 ataaattatt aaaagataag caagatgaac tgatgcgtca attcatcctg ttgattcgaa
    55801 agaacaacca gctgcgtcaa gaaatggaag agtctatgac agaagcaatg tctgattttg
    55861 tattggcaaa tgcttcgatc acggaacctt tcatcgaaga attatttgtt ttgccggcgg
    55921 aaaacgttga tttgtctatc gtagacaaaa atatcatgag tgtaaaagta cctgtgatga
    55981 attttgaata tgatgaacag ctgacagaca cacctttgga atacgggtat ttgaattcca
    56041 gtgccgaact ggatcggtca atcgatcggt ttactaccct gcttccaaaa cttttggaac
    56101 tgacagaaat cgaaaaaact tgtcaactga tggcgagtga aatcgaaaag acacgtcggc
    56161 gagtcaatgc attagaatat atgacgatcc ctcaattaga agaaacgatc tattatattc
    56221 gtatgaagct ggaagaaaac gagcgcgcag aagtaacaag gttgatcaaa gtaaaaaata
    56281 tgggtaccac tgactaagtg gtatcttttt ttaaaagagg aaaacgatga ttaaacaaag
    56341 caaacaaata aagaaacgtt tgccggctgt tcagcttctc gcattaggat tttttctcct
    56401 gattttagtt ggcggcggcc tacttaccct accatttttt agtaatagtg ggcatgggac
    56461 aaattttatc gatgcgcttt tcactgcaac ttctgctgtc tgtgtaacgg gattgacaac
    56521 attgaataca gcagagcatt ggaacagtgc tggtcaattt ttgatcatgc ttttgattga
    56581 gatcggcggt cttggtttta tgatggttcc gattctatgc tttgcattga taaagaagaa
    56641 agtcagtctc agcacacgta ttatattaaa agaagcgctg aatctagaag aagtatcagg
    56701 tgtgatgaag ctcatgcttt acatcctaaa attggccttt gttatccaat tgattggtac
    56761 ggttgcttta tcttttgtat ttgtgcctga atttggctgg ttgaaaggta tctggtacag
    56821 tttgttccat gcaatctcta gtttttgtaa tgcagggttt gatttgttag gagacagttt
    56881 agccaatcac cagcaaaatg tttatttgat catggtggta tctgctttga tcatttctgg
    56941 tgggttaggc ttcatcgtat ggcgtgattt actggaatat catcagaaaa agaagatgac
    57001 gattcattca aaaatcgcat taaccgttac aggtaccctt ttattaggcg gattcgttgt
    57061 gttctttttc acagagcgca atggggcaac gctagtggaa gggaatatgt ttcaacgatt
    57121 ggcaaacacc ttttttatga gtgtgacacc tagaacggct ggatattatt cagttgatta
    57181 cctccatatg agccatgcag gtctgatttt aacgatgttt ttgatgtaca tcggcggaac
    57241 atctgggtcg acggccggcg gattgaaaac aactacgtta ggtgtgttgc tgatccagat
    57301 gcgttcgatg ttgaaaggac gtacgagagc ggaagcattt ggccgtacca tccgacaagg
    57361 cgcagtgttg cgggcactta ctttattttt tgttacgttg acgttgtgtg tagtcgccat
    57421 catgatttta tcggtgactg aaacgatacc taaaacttct ggcatcgaat atattgcttt
    57481 tgaggtcttc tctgcgtttg gtacagtagg tcttacgatg ggattgacgc cagacttgac
    57541 tgcaataggg aaattgatca ttatagcgct tatgtacatt ggacgagttg gtgtattgac
    57601 tgtggtcttc tctctgatga caaaagcaca aagaacacaa tcaaaataca aatatccaga
    57661 agaaagtgtc atgattggat aatttcatct tctgacagaa acctagtgat ttagtaaaat
    57721 aagaaaataa aataattttt cttgcttctt ggatacttta agtgcaaaat gttcgtt
//
LOCUS       DAYNVV010000011        56316 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.011, whole genome shotgun sequence.
ACCESSION   DAYNVV010000011 DAYNVV010000000
VERSION     DAYNVV010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56316
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.011"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            266..1111
                     /locus_tag="ACGXWR_000820"
     CDS             266..1111
                     /locus_tag="ACGXWR_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFK0802424.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLLEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1392..2612
                     /locus_tag="ACGXWR_000821"
     CDS             1392..2612
                     /locus_tag="ACGXWR_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFK0802425.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2609..5329
                     /locus_tag="ACGXWR_000822"
     CDS             2609..5329
                     /locus_tag="ACGXWR_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFK0802426.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5313..6257
                     /locus_tag="ACGXWR_000823"
     CDS             5313..6257
                     /locus_tag="ACGXWR_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFK0802427.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6326..7336)
                     /locus_tag="ACGXWR_000824"
     CDS             complement(6326..7336)
                     /locus_tag="ACGXWR_000824"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFK0802428.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7516..7860)
                     /locus_tag="ACGXWR_000825"
     CDS             complement(7516..7860)
                     /locus_tag="ACGXWR_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFK0802429.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7853..8287)
                     /locus_tag="ACGXWR_000826"
     CDS             complement(7853..8287)
                     /locus_tag="ACGXWR_000826"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HFK0802430.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8425..9162
                     /locus_tag="ACGXWR_000827"
     CDS             8425..9162
                     /locus_tag="ACGXWR_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802431.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9155..10366
                     /locus_tag="ACGXWR_000828"
     CDS             9155..10366
                     /locus_tag="ACGXWR_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0802432.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10570..11352
                     /locus_tag="ACGXWR_000829"
     CDS             10570..11352
                     /locus_tag="ACGXWR_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HFK0802433.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11422..12084
                     /gene="trmB"
                     /locus_tag="ACGXWR_000830"
     CDS             11422..12084
                     /gene="trmB"
                     /locus_tag="ACGXWR_000830"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HFK0802434.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12182..13936)
                     /gene="ade"
                     /locus_tag="ACGXWR_000831"
     CDS             complement(12182..13936)
                     /gene="ade"
                     /locus_tag="ACGXWR_000831"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HFK0802435.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14068..14997
                     /gene="comGA"
                     /locus_tag="ACGXWR_000832"
     CDS             14068..14997
                     /gene="comGA"
                     /locus_tag="ACGXWR_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HFK0802436.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            14954..16003
                     /gene="comGB"
                     /locus_tag="ACGXWR_000833"
     CDS             14954..16003
                     /gene="comGB"
                     /locus_tag="ACGXWR_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HFK0802437.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16000..16278
                     /gene="comGC"
                     /locus_tag="ACGXWR_000834"
     CDS             16000..16278
                     /gene="comGC"
                     /locus_tag="ACGXWR_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HFK0802438.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16253..16723
                     /gene="comGD"
                     /locus_tag="ACGXWR_000835"
     CDS             16253..16723
                     /gene="comGD"
                     /locus_tag="ACGXWR_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HFK0802439.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16695..17042
                     /locus_tag="ACGXWR_000836"
     CDS             16695..17042
                     /locus_tag="ACGXWR_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802440.1"
                     /translation="MVAIQKELNKTGFVLLESLTALMIASVCVYLVSFGQLFLLQAEK
                     KSGEELLFIRMIYEDIKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAI
                     SIEKTSNSSIYAD"
     gene            17005..17430
                     /gene="comGF"
                     /locus_tag="ACGXWR_000837"
     CDS             17005..17430
                     /gene="comGF"
                     /locus_tag="ACGXWR_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HFK0802441.1"
                     /translation="MKKQVIPAFTLIECLIGLMILSSLLLTFNLLIQQTIQVSEFLQR
                     KDQKEWLIFLAQLEEELKSSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQ
                     PMLTSITELQLLEKEHTISFYVHFENGEDGYAIWTKNDQ"
     gene            17402..17761
                     /gene="comGG"
                     /locus_tag="ACGXWR_000838"
     CDS             17402..17761
                     /gene="comGG"
                     /locus_tag="ACGXWR_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HFK0802442.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17933..18940
                     /locus_tag="ACGXWR_000839"
     CDS             17933..18940
                     /locus_tag="ACGXWR_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFK0802443.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            18965..20149
                     /locus_tag="ACGXWR_000840"
     CDS             18965..20149
                     /locus_tag="ACGXWR_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HFK0802444.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20586..22169)
                     /gene="abc-f"
                     /locus_tag="ACGXWR_000841"
     CDS             complement(20586..22169)
                     /gene="abc-f"
                     /locus_tag="ACGXWR_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="HFK0802445.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22274..22402)
                     /locus_tag="ACGXWR_000842"
     CDS             complement(22274..22402)
                     /locus_tag="ACGXWR_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802446.1"
                     /translation="MMRMTKITSNENYQRYHIAFSHAIGFTVAVDGTSLSKTVEFT"
     gene            complement(22747..22890)
                     /locus_tag="ACGXWR_000843"
     CDS             complement(22747..22890)
                     /locus_tag="ACGXWR_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HFK0802447.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23113..23592)
                     /locus_tag="ACGXWR_000844"
     CDS             complement(23113..23592)
                     /locus_tag="ACGXWR_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFK0802448.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23665..23949)
                     /locus_tag="ACGXWR_000845"
     CDS             complement(23665..23949)
                     /locus_tag="ACGXWR_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802449.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24027..24221)
                     /gene="ssrS"
                     /locus_tag="ACGXWR_000846"
     ncRNA           complement(24027..24221)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACGXWR_000846"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24293..25579)
                     /locus_tag="ACGXWR_000847"
     CDS             complement(24293..25579)
                     /locus_tag="ACGXWR_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HFK0802450.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25717..26388
                     /locus_tag="ACGXWR_000848"
     CDS             25717..26388
                     /locus_tag="ACGXWR_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HFK0802451.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26354..26842
                     /locus_tag="ACGXWR_000849"
     CDS             26354..26842
                     /locus_tag="ACGXWR_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HFK0802452.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26855..27802
                     /gene="prmA"
                     /locus_tag="ACGXWR_000850"
     CDS             26855..27802
                     /gene="prmA"
                     /locus_tag="ACGXWR_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HFK0802453.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27803..28567
                     /locus_tag="ACGXWR_000851"
     CDS             27803..28567
                     /locus_tag="ACGXWR_000851"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HFK0802454.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28800..31013
                     /locus_tag="ACGXWR_000852"
     CDS             28800..31013
                     /locus_tag="ACGXWR_000852"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFK0802455.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31024..31470
                     /gene="dtd"
                     /locus_tag="ACGXWR_000853"
     CDS             31024..31470
                     /gene="dtd"
                     /locus_tag="ACGXWR_000853"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFK0802456.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31641..32900
                     /locus_tag="ACGXWR_000854"
     CDS             31641..32900
                     /locus_tag="ACGXWR_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HFK0802457.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(32989..33936)
                     /locus_tag="ACGXWR_000855"
     CDS             complement(32989..33936)
                     /locus_tag="ACGXWR_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFK0802458.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHIPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34330..35622
                     /gene="hisS"
                     /locus_tag="ACGXWR_000856"
     CDS             34330..35622
                     /gene="hisS"
                     /locus_tag="ACGXWR_000856"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HFK0802459.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35637..37406
                     /gene="aspS"
                     /locus_tag="ACGXWR_000857"
     CDS             35637..37406
                     /gene="aspS"
                     /locus_tag="ACGXWR_000857"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HFK0802460.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37515..38390
                     /locus_tag="ACGXWR_000858"
     CDS             37515..38390
                     /locus_tag="ACGXWR_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFK0802461.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38656..40539
                     /locus_tag="ACGXWR_000859"
     CDS             38656..40539
                     /locus_tag="ACGXWR_000859"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFK0802462.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40614..40898)
                     /locus_tag="ACGXWR_000860"
     CDS             complement(40614..40898)
                     /locus_tag="ACGXWR_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFK0802463.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40888..41622)
                     /locus_tag="ACGXWR_000861"
     CDS             complement(40888..41622)
                     /locus_tag="ACGXWR_000861"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HFK0802464.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41751..42374
                     /locus_tag="ACGXWR_000862"
     CDS             41751..42374
                     /locus_tag="ACGXWR_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFK0802465.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42566..43687
                     /locus_tag="ACGXWR_000863"
     CDS             42566..43687
                     /locus_tag="ACGXWR_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFK0802466.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43694..46822
                     /locus_tag="ACGXWR_000864"
     CDS             43694..46822
                     /locus_tag="ACGXWR_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFK0802467.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46841..50035
                     /locus_tag="ACGXWR_000865"
     CDS             46841..50035
                     /locus_tag="ACGXWR_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HFK0802468.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50181..50888)
                     /locus_tag="ACGXWR_000866"
     CDS             complement(50181..50888)
                     /locus_tag="ACGXWR_000866"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFK0802469.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51653..52051
                     /gene="spxA"
                     /locus_tag="ACGXWR_000867"
     CDS             51653..52051
                     /gene="spxA"
                     /locus_tag="ACGXWR_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SpxA"
                     /protein_id="HFK0802470.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            52383..53036
                     /locus_tag="ACGXWR_000868"
     CDS             52383..53036
                     /locus_tag="ACGXWR_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HFK0802471.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            53262..54260
                     /locus_tag="ACGXWR_000869"
     CDS             53262..54260
                     /locus_tag="ACGXWR_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA family protein"
                     /protein_id="HFK0802472.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            54436..56244
                     /gene="pepF"
                     /locus_tag="ACGXWR_000870"
     CDS             54436..56244
                     /gene="pepF"
                     /locus_tag="ACGXWR_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFK0802473.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        18529 a         9719 c        11677 g        16391 t
ORIGIN      
        1 taatagagtc ttttatgaat atcgaagtta gtttttcacc taacttcgtt ttttatagtt
       61 ggttattata aaatagtaat atagctgatt tggattcaat tcatatttat ttataaatca
      121 aaaatacaga gaatagtata taaatgtcct ttcctattct taaaatgatg tttgtactta
      181 cttaaattag gtataattag tatatgtttt gtgagaaatt tagacttaca ataagcagtg
      241 aatttataat caacgtatag gagacatgga tgaaatgaaa ctaattggta tagatttaga
      301 cggtactctt ttgaattctg accagagcat tagtcaaaaa aatgcaagaa caatgaaaca
      361 tttactggaa gactgttttc cattcatttg ttctggaaga gaagtagaag acattaataa
      421 tattctcaaa aaatctggtt taaggatacc agcagtaggg ttaaatggtt ctgttggatt
      481 tgatggagaa aaaaagatat ttgagtcttc cttcgataaa aatgatgtaa aaaaaattga
      541 ttctgtccta tcgaaatttc caaccaaaat atatacaaat ctcggaagtt atgaatctca
      601 gaattataaa aataaaatga aaaaaatttt tcacgaggta gggagtgaat tttctatcaa
      661 agagctaaac tatgagcttg agtatgaaaa atctatttgt tcaatccctt ataataatat
      721 tgaggaaatt atagaaaagg atgctatcag catttacaaa ttttttattt ttattcctaa
      781 tcgtcaattg aaagctaata tatttaacca tttgaaaaag atgctaaatg tgtctgttac
      841 tgaatcggca cctgtaaata ttgaaatcgt acctcaaaat gtatctaaag gtgtggtgtt
      901 tgatcgtttg gaatcaatct acaatttaaa gaaacctttg agaatcgcga tcggagatag
      961 tttaaatgac ttatctatgt ttgaaagtgc agatattagt tttgcaatgg gaaatagtca
     1021 tcaagaaatc atgaaaaaag ctgattatgt cactgtttca aatgataaag acggagtatc
     1081 tcaagcattt gaaagaattc ttaccatata aactaattaa ggtagtatag aacatagaat
     1141 tctaaatacg gaaaaatgga gcataaattc cagtacaaat agtacttctt cagtgtcaaa
     1201 cgaagcgaat ataacataga tatttaggat tgtgacaaaa atcatgtcac aatctttttt
     1261 tcgaataaac ttattttttg aagtcggcca tttatcgtaa tttctttgca taatacgaac
     1321 aaattttcgg ttattgatga aaaaaaacat tgaaaatggt atgataaaag aaaaaaagga
     1381 ggaaattttt aatggtgaaa tttatccatg cggcagattt acatatggat cggtcatttg
     1441 aaggactgac aactcttgat aaaactgtac aggaaaaact attgaagacg aatctgaccg
     1501 ttttatcaaa tatcattgaa caggcaataa taaataacgt tgattttgtt ttacttgcag
     1561 gagataattt tcatcaaaat cgtccttcat taaaaataca gaaacatttt tcagaacaga
     1621 tgaaacggtt agaaaagaac catatacctg tatttataat attcggaaat catgatttct
     1681 atcaaaaaga gcggtattgg ttctcctttc ctaaaaatgt ccatttattt acatccgaaa
     1741 cggtagagac aaaaaaaata acgataaaaa gtggagaaac tgtctctctc agtggattta
     1801 gttatcgtca accgtggatt caaaaagaca aagtgatgga atttccttct agagaactca
     1861 cagattacca tattgggttg taccacgggg aacctggcgt ctctcaaaaa ggaaactatg
     1921 ctcctttcca accctcaaag atgcaagaaa agggatacga ttattgggct ttagggcata
     1981 tccatgtgcc aacggtctta aatgaaaagc aaacaattgt ttatccaggt gcgcctcaag
     2041 gtcatactaa aaaggaacaa gcttctacat ctattctact agttgaatta agtaaaggaa
     2101 gttgccaaat acatccgatt aaagtagcag aggtctattg gaagacaaag gaaatatcat
     2161 tgaggaaagc aagaacgaca aaagaggtca ttgttcacat tcgtcagcag ctttcaaaag
     2221 tagaggatgg atttagttta attgagataa aattaaaaga ttatgaccat ctcaatacag
     2281 atgttttgga acggatacaa tcaggagagc tattagacta tttgttagag gaattctcag
     2341 ataggataaa tgatttcttt atttggcgta tttctctcat agagaatact ttttatacga
     2401 agaccccact tgctgcttct gctaaattga tggaacagtt atttcaatac tatcagacac
     2461 ctcaagattt ccaacaaatt ttaaatgaag tatatagtca tcaagaagcg gctagaatat
     2521 tgagcgaact gccggaatat caagaagaaa cacttgaaaa agccaagcag ctgcttaatc
     2581 aagatttttt atttgaggag gatcaggaat gaagatttta aggatcgaga ttgctgcttt
     2641 tggaaaatgg cgtcaaaaaa gttttgactt ttattcaggc aatcagctga tctatggggg
     2701 aaacgaagca ggaaaatcaa cgatttatca atttattcaa gcaatattat ttggtttccc
     2761 ttcaaaaggc cgtaaaaaaa aggattatac accaaaagac ggctcagcct atggcggcaa
     2821 aatatggctt aaacatcctg tatatggtga atttgctgtc gagcgctaca agcagcaaaa
     2881 tcgcggaaaa tcgaaggtgt ggctggggga tcaagtggga agtgatgagt tactagaaaa
     2941 actgatcgca cctttgacga aagagttatt ccagcaggta tttactttcc agcaagagca
     3001 gttgatggaa ctagatcatt tgagagaaaa agagctacat gatgcgctga tttctttagg
     3061 catcacgggc agttctcaag tattccaaaa gcggcaagaa tattatcaga aagcacaaca
     3121 attattcaag aaaaaaggcc aaaaattact aatcaatcaa aaattaaatg aatggaaaga
     3181 gctgcaagaa aaaattcatc aaaaacaaga acaggaagct tattttggca agttgatcca
     3241 acaagaacag gaatacgagt cgcaacagca gcagttattg gcacaattaa aagaggcgaa
     3301 caaacaattt tcattagcca gacagcaaga acttaatttt tctttatatg aagaatggca
     3361 atctctcaaa aaaaacagca ctacaggtct tcctgatgag caacttcttt tagatctgga
     3421 gtctttctcc aaacggtatc agcaaacaaa tgagcgtttg gaagaattag aagcaacact
     3481 ggaaaagcat agcgggatgg atcagcagtc agccagatat tatttttatt tagagcagga
     3541 gcaggaacta aaagatctcc agcaacttca atttacagcg gaacaattaa acgaagaatg
     3601 gcaaagatta caaattgaga ctagagaaac aaattcagaa ttgaagattt tggaacaaag
     3661 gtggcattgg cagaaaaatc cgttaccgga agaattttta tatgaagaag aatggaagca
     3721 tcttctggct gaagaaagaa ggattgctga tctagaaagc cagatttctg tgcgtctcca
     3781 aatagctaaa gaacagcaag agatgattga agcagaagtg aatgacttgg aagagaccta
     3841 tccagcatta ttacaaaatc agtcagagat agcaccagtc tcttcatcta aaccgtatat
     3901 gctgatggct ggcggagcaa taatcattgc aggtatattt gtaccaatgc ccttgaaagt
     3961 gatcctttta ctaattggtg caggcatgat tggctatttc ttctacaaaa ggcaaccaaa
     4021 aattaaaact aaaaatgatt tctctgagat aaaaggaatg tggcaagaaa aactaggaca
     4081 acttgatcta gccttagctc aattagctga agcagaagaa aaacaaaaga gaactggaga
     4141 agaaaaacag attcttcagc aagaagtata tcgttttgcg gatcatcggc acttaggaaa
     4201 gatggatacg ctcaaactca tgaaagaata tggacaggaa gtcatagatt atcagaaatt
     4261 atatggcgta tttgagcgga aacataaaag agaacaggaa atacaagaaa aactacgaca
     4321 aatcgaccaa aaatttgagt ttgttaaaga atggttaccg atacaagata agacaatttc
     4381 agaaaaaatg gtattgcttt cccgttttat acaagagatg gaacagatga aatttgccag
     4441 aagctatcag caaaatactt tattgaagca agaaatcaat caattgaaaa agaaacaaaa
     4501 agtatggata caagaataca gcgaacaatt gactcaagca ggcttatctt atccttcgga
     4561 agtacctgtc tttttacaaa aagccaaaca agccgaacag cagatgaaaa gatacaatga
     4621 attatcggaa atgcttactc cactatttcc tgaagagctg acaaaagaga aattatctgt
     4681 aagactgcgc caactgaaag aaaagcaatc ccaactccag caagaagaaa aagaagcaag
     4741 tgaaaatcgg caacgactcc aacttcaagt agaagagttg caaagagacg gcacattgga
     4801 cgaactttat caacaagcta gccggcaaaa agcaaaatta caggaattac tggaggaatg
     4861 gggagcactt gaaatcgccg ggacattctt aggtgatctt tcaacagaga tgagtgaaag
     4921 acaattaccc cagttgttaa gagcagcagg tgattattta ggtattttaa caaaaggaaa
     4981 ttatcagaag atattactga aaaatgatac actgacttta acagacggat atacagaatt
     5041 tcccatctat gagttatcta caggtacgaa agatcagctg attatggcga tgagatttgc
     5101 ttacctctca ttagaagcta accgttcgat atgcccgatc atcattgatg atggctggct
     5161 tcattatgat catcagcgaa agtatcaatt agctgaactt ttagctaaat ttggagaaaa
     5221 gtatcaaata atttgttttt cttctgataa agaaatggta agctattacc atgagatgaa
     5281 ccaaatcgta aaacaattag aaggagcaaa taatgaaaaa aattcgtgat ttagtaatcg
     5341 atgagcagtt tgaacaattt gtcctgatca aaagtgcaga tgtaagaatc gctaaaaacg
     5401 gaaaaaaatt tattgctttt actttccaag atacttcagg tactatcgat ggtaaatact
     5461 gggatgcttc ggaggaggaa atcaataaat ttacagccgg cacagtcgtt tttctaaacg
     5521 gtaaaagaga ggtttatcaa ggaaaccctc aagtaaagat tcttcatatg cgcttaacaa
     5581 gggtagatga gccaggagag cctagtttat acatggaaag agcccctttg aagaaagaag
     5641 aaatggaaga agaaatcaat caattgttgt ttgagatcac caatgcgcat tggaatcgta
     5701 ttgttcgcta tctacttaat aaatatcaaa aacaattttt tgagtttccg gcagcaaaaa
     5761 gaaaccatca tgcatttgcc agtggattag cttatcatac tttgacaatg cttcacttag
     5821 ggaaatcaat cgccgatgaa tatcctgagc tgaatcgagc attgttgtat gctggtatca
     5881 ttttgcatga tttaggaaag gtgattgaac tttccggtcc tatgtcgaca gaatatacgc
     5941 ttgcaggaaa tttgatcggt catctggtat tgattgacga agaaataact aaagcctgtc
     6001 ttgcgttgaa aatcagcgaa gctgacgaag atgttctcgt attacgtcat atggttttag
     6061 cacaccatgg cttattagaa tatggctcac ctgtacgtcc aagaataatg gaagcagaaa
     6121 tattacatca aatcgacaat atcgatgctt cgatgcagat gatgttgact tcgattcgtc
     6181 aaacagaacc aggaaaatac accgatcgga ttttcggtat ggacaaccga agtttctatg
     6241 taccaaaaga tttatagcaa aaatttattt ttttcattca aaacaaaaaa agcgagacat
     6301 aagtcttcgc tttttttgtt ttcttttatt ttgatgaatc agttgtttct tcagttgaag
     6361 attcttttgt tgaatcagtt gattttgtgt cagaactctt tgttgaagct gtagtttcac
     6421 ttgagtcttt cgtacttgat gaagttgttg tgaatgcact caacacattt tcaaaggcat
     6481 catctttgat ttttacattt gcatctttta attcttcacc gattacttta gttgtgaatg
     6541 cattgtcact tagtttagtt tcagtagcga tatcttttag ttgatctttg tatttatcca
     6601 tgtcattgcc tttattttgg tttttcacca ttttgacaac gtagtattct gtcgcataag
     6661 aagtaggatt tgttgtagta ataacatcgg agatctcacc gtctttcaat ttgaaagctg
     6721 cttcttttac ttctgcagga atagttgttg tcgttgagtc gaatttaact ttaccgccat
     6781 cttcttttgt ctctgtatca gttgatttgt ctttggctaa tttagagaaa tcatctccat
     6841 catccgctga ttttttcaca tcttttgctt catcttcact tgataatttg atgatttgtg
     6901 cttctacttc tggatggaaa gatttccaag cagttttcaa atcgtcatct gtaatatcta
     6961 cgtgagcttt caagccagct tcaaaagcta aattgttacg aatatattct ttataagtat
     7021 ctttcgtata tccagcagct tctaattgtg attcaaaagt atcacctaat gatttcgctt
     7081 gtttgtcgta ttctgcatcc acttgcttat cggttacttt atcgccatat ttgttattga
     7141 atactttata aatgatcatc cgttgtacta aggattggtt cgatgattca agttttgctt
     7201 catcatagaa atcagataca gtgatcgttc cgcctttcat cgttgcgata tctttattag
     7261 tatcgcctga acaagctgct agagttaaaa cagccaacgc actagtagct gccaaaataa
     7321 ttgatttttt tttcattaaa atttgcactc ctgtaattag ttattatttt tatatattaa
     7381 ctataccata tcccatttcc tttaaaaacg ttgtcgtggt agtttcaaac aaaattcaaa
     7441 atttcatcac attcctagga aatacgcaaa cttttctcac ttatatagtt aaatctgttg
     7501 agaaaataat cattattata tttgttcagg atactctggc agatcagctt ttagtttttc
     7561 tacttgttca ttgatttgtg tgatacgtgg ttcggcttgg aatttaaaat cttcgatatc
     7621 ttttttgatt gcttcttgga aagcaggaat cacagattca gctgtttctt ttgtttcgat
     7681 caatgcgctt ttaaaatgat tcaggctgtt atttaaatca tttgtcagag ttgttgcttc
     7741 ttccaattct tcgatcagtt tctttcttgt ttcattcccg ctcctgggcg ccaataacag
     7801 acctccgaca gtgccagcag cagctccaaa taacagtcct ttgaaaaagt ttttaatcat
     7861 cgcaggacac ctgctttacg attgtttctt gaatagcttt tagttcttcc gatccataac
     7921 tatcttgatg attgacaaag tgaatagaaa aatcatcctc tttgctgtag cgagggacta
     7981 aatggatatg tgaatgaaaa acagattgat aggctagttc acggttgtta ttcaagatat
     8041 taagaccttt catttctgga aaagcttttt ccaatgcttg agcaatctta ggcacacgcg
     8101 aaaaaacctc tcctgcaagt tcgggatcat attcaaaaat atctgctaca tgacgtttag
     8161 gcacaactaa tgtgtgtcct ttcgttgctt gagagatgtc taaaaaagca tagaccttgt
     8221 cgtcttcata tattttatag cttgggattt cttgattgat gattttgcaa aaaatacagt
     8281 tttccatata aaacatcctt tctataaaga ataaatactt cagcttaact ttaccataag
     8341 ttaaagctat tgtaaggaaa aaaacaaaat accgtcattt tcttcgtggt ataataaata
     8401 aaaataaatg gcggaggaaa aagaatgagt ttaattatcg atcatgtcac aggggggtac
     8461 ggacatctcc ctgtgttaaa agatatcagt ttcgatgtac agcctggaga gatagtaggg
     8521 ttgattggac tgaacggagc agggaaaagt acgaccatca agcacattat cggtctgctg
     8581 gaagcttcaa aaggaacgat agaaatcaat catctatcct taaagaaaaa tacggaagaa
     8641 tatcgcaaac aaattgggta tattccagag actccttctt tatatgaaga attgacattg
     8701 agagaacata tcgaagtcac tgcgatggcc tacgatatac ctatggatat agcaatgaaa
     8761 agagcagaaa agttgttgga gacttttcgg ttatctaatc gtcttgactg gttcccagct
     8821 aatttttcaa agggaatgaa acagaaagtg atgatcttat gcgccttttt gatcgagcct
     8881 tctttatata tcatcgacga accattttta ggcttggatc cactagctat caatgcattg
     8941 cttgaattga tggtagaaat gaaaaaagaa ggagccggta ttttgatgtc tacgcatatt
     9001 ttagctactg cagaaaaata ttgtgatcgt tttgtggtct tacataacgg agagatacga
     9061 gcagacggtt ctcttgagat gttgagaaaa gaatttcagc tgccggattc ttctttggac
     9121 gaaatctata ttgctttaac aaaggagcag gcacatgagt agtttttttc aaaaacgttt
     9181 agcaagacat caaaagaaaa tgatgaaata tatgcgttat gtattgaacg atcattttgt
     9241 tttagtttgt cttttcttga ttggcggtgt gggattatat tattctaatt ggttgaaaac
     9301 cctgcagcca ccgtttgcaa ttggagggct cataatctct gtattttgga tgctctgttt
     9361 attcgtgggt aagatggcta cttttgcaga ggcagcagat attgtttttt tacttcctaa
     9421 agaaaaagaa atgcaaacct atttggaacg agcttttcgc tattcttgca tttttccgtt
     9481 gatctttttg atattggcat gcggattggc catgccatta gtggtggtta gtacggagca
     9541 atccttttcg atgtttttcg tctatctgat catattatgg agtttgaaat tcagtcatct
     9601 gcaaatcaag agagcagaat tgtttcgact agatcaacaa gttattcgtt attggaaatt
     9661 aggctggttt ttttcttctc tgatcttttt gtttctatca ttttattggc taatatgggc
     9721 aggaatagca ggtgcattag tacaggcaag tctatattac tggtttttgt ggaagcaaca
     9781 agaaaaagga ttggattggg agaaaatggt gcatgtagaa gaacataggt tgcatcagat
     9841 ctatcaattt atcaatttat tcacagatgt tcctgaaatt acggcaaaga tcaaaagaag
     9901 acgctatttg gatcctatat tgactcatat taaaagagaa tcaaaaaaca cttatcttta
     9961 cttgtttgca agaagattgg caagaggttc tgattttagt ggtctttatt tccgattagt
    10021 aattataggt gggttattga ttgccggagt agtcgacttt tattttagtc tgattatcgg
    10081 tttcttattt ttatatttga tcggtttcca actgttacct ttagcgaacc agttccgcta
    10141 tatggttctc gttcagcttt atccaatcca taagaatcag aagaagcagg cgattcagta
    10201 tctactcaca tgggtattaa ttatcgcgtc ggttattttt ggtttgattg ctgcagtcgt
    10261 attagatggg cagcagcgat gggttccgct agcggcttat ttgattgtta ctatgctctt
    10321 tgttaaacta tatgtaccaa ctcgtttgaa gaagatgtca gactgaaaac aaagctgtgt
    10381 agggtaaaaa tgagaatgaa aaatagagcg ttgacagtaa gaatgctgtt cgttctattt
    10441 tttttgagaa aagctggttt tttgaatggc aattaaatga aaaagaacgt atatgtgctt
    10501 gacgtgtagt gttcaggcga ctagaataat aagtactgca aaacaaagag taagaggacg
    10561 ggagaatgca tgatggagtt tcagttagac caagagtggc ggttacgtcc catcaaaggc
    10621 gacacaggaa aaacatacat aggcatgcgt gatgaggaca aagtctttat taaacgaaac
    10681 acgactccga tgttggctgc tctttcaagg gaaggaatta caccaaaact tgtttggaca
    10741 aaacgaacgg ggaatggcga tactttgaca gcacaagagt ggctggaagg tcgcttgctg
    10801 actcctaatg agattggtca aagaaacgac gtgattgatg ttttgtacca tttacatcat
    10861 tcaaattctc ttaaaaccat gctgacccgt atcggtggtc gtgtcatgac gccggagaag
    10921 atgctgcaaa aatatgaaaa agaattaccg gaagaactcc agaaaaatca atttctgcaa
    10981 attgtccatc gttttcttcg tgagcagatc ccgtcaatag ataaggaaaa cttatcagta
    11041 gtacacggag atgtaaacca tcgtaattgg ttagtatgta aaaattattt atatctagtc
    11101 gattgggatt caatcatgtt tgcagaccct gcggtggata ttgcaacgat tttaggaaat
    11161 tatgtgccac tgtctagctg gaatcagtgg ctgatcagtt atggcatacg cccgactgac
    11221 gaaatgcttg aaaaatttca ttggtatgcg gccatgaatt tgctccaaga aatcaccaga
    11281 tattgcaaac gtgaagatca tcgacggatg aacgaagaaa ttttacaatt aaaacgaatt
    11341 ttcagtggct gaggtttggc ccaaactctg cggagatttg gccagacctt tttaattaga
    11401 ggaaaggaat ggagataaat aatgcgtgtc cgaaatcgtc cgggagcagc ggaaatgtta
    11461 gcggctcacc cgaattttgt aattagtgat ccaacattgt ggaagggaaa atggaatgaa
    11521 ttgtttgaaa acgatcatcc aatccacatt gagattggta tggggaaagg ccagttcatc
    11581 actggaatgg caaaagccca tcctgaaatc aattatattg gagtagaaat gcaggtcagt
    11641 gttgtttcga ttgcactaga caagttgatc gaacaaccgc ttcctaacct gaaacttcta
    11701 catgtggatg gatcagcgtt gacagagtat ttcgctgaca gcgaagtaga tcaaatctat
    11761 ctgaattttt ccgatccatg gccaaaaaaa cgtcatgaaa aacggcgatt gacatataag
    11821 acttttcttg ctgtagatga acagattctt cgtccaaatg gagaaatcca tttcaaaaca
    11881 gataatcaag gattgtttga gtattctctg gcaagttttt ctcaatatgg catgatcctc
    11941 aaacaggtat ggttagattt acatcaaagt caatttgaag gcaatattat gacggagtat
    12001 gaagaaaaat tttcttcaaa aggtcaacgt atttatcgag tagaagctca atttcaagat
    12061 aagaccaaaa agaaaagtct gtgaaactaa ctttctgctt tcataaaaac attaatatcc
    12121 ataaataaat cccagaaaat gaacattaca gatgtaatgt attttctggg atttatttga
    12181 tttaaaatgt atttatttca tcggtttttc cacaaggtgg aatcaattgg aagcgagaaa
    12241 atgaaaataa tcctttgtcg gtgatcttca attcgggtat gacagataat gttaagaaag
    12301 aaagtgtcaa aaaaggatca aaggttttag ctgctcctag ttgatgtgct ttagttatta
    12361 attcattcaa ctgttcatag acgatcgaaa aaggttcctg tgtcatgatt ccgcctatag
    12421 gaagagaaac acaagctatt tcctgctgtt tgttgacaac ggtcatcccg ccaccttttt
    12481 gaatcaaaag attagcagca tacagcatat cctcgtcgtt tgtcccaacg acaactagat
    12541 tatgcgagtc atgggcaatc gttgtcgcta tcgctccttg tttcagctga aatcctttca
    12601 ctatgcctaa tccaatgttt cccgtttgat ggtgacgctc gatcaccgca atctttaatt
    12661 ggtctttttc gattgaagga atgaatcgtt cgccttgtcg gtccactttt tctaccaaat
    12721 ctttagtcac tagactattc gggataattt cgatcacatg ggcttgtgaa gaagaaagaa
    12781 gcagctctaa cgaatgtgga tttaatggtt gagcgtttag ttttggcaga caacacgtat
    12841 atgaatttga atgatcagca aataaatggt cttggagttg cccagattga acaactaatg
    12901 ttcccttata gaaaacttca tgaattggca gcttggtaag atcgtctgtt aagaagaaat
    12961 cagcttgata cccaggggca atcgcaccta gtgttttcaa atcaaaacat tctgctgcat
    13021 tcaatgttgc catctgaatg gcttgtaatg gatcgattcc aagtgcaata gcttgacgga
    13081 cgatatgatc gattgatcct tcttttacta aatcattgat cagtttatca tcggtgacaa
    13141 agaagcatct tcttgaattt tcaggtgtga tcgccggtag tagcgatgcc agatcttttg
    13201 caacggtccc ttctcgaacc attaaataca taccaagatc caaacgttct ttagcttctt
    13261 ttgcagttgt agcttcatga tccgtccgaa tacctgctgc aggataaaca tttaactctt
    13321 ccatgccgat accagctgca tgcccgtcaa tttttttctt atgctggtgc atcaattgga
    13381 tcttttctag gatgtctgtt tcattatttg ctactgcttg atagttcatg acttcagcta
    13441 agcctaaaac ttcgggtttt tgtaaaaaag gggctaattt ttttgcattt aaatttgcac
    13501 cattggtctc aaaaggggtt acaggtacac aagaaggtag cataaaaaag atattcatga
    13561 gtgtttgtct tgcatcttct atcataaact caagacctgt actcccagca atgtttccta
    13621 tttcatgggg atctgtcact acagtagtaa ctccatgaag caaggatact tttgaaaatt
    13681 cgcttggtga taaaagtgag ctttcgatat gcacatggcc atcgatgaat cctggcacta
    13741 gatattgccc attagcatta tgtacgcttt ttccttcgta ttcaccgatt cctacgatca
    13801 ttccttcgca gattgctaca tctttttcca tgatttcttt cgtaaagacg ttgacgatct
    13861 tagcatgctt gatcactagg tcagcaggct tttttttact tgctacttcg atatatttcc
    13921 ttaatgttgt ttccaatgga gtgcctccca agataaattt ttataagtat aacataaatt
    13981 cggtttttgc caatattttt ttgtaaattc attttatttg aaacaaaaag atcaaaaaga
    14041 cgtatgtttt ttgtggaggg gagaataatg gaaataaaac gattatcgga tcaaatgata
    14101 agtgaaagtt ttgccaaaca tgcccaagac gtatatatat tgccagcttc agaagtattt
    14161 tacatctatt ttcgctatgg aaaaaaacga acattctgga agaaagtctc ttcggcagat
    14221 ggacagcaac tgatctcaag atttaagtat ttgggacaga tggatatcgg agaaaaaaga
    14281 aaagctcagt taggtgcatt tacttattct ttagaaaaac aggaagttcg tctgcggttg
    14341 tcttctgtag gagattacct tcaacgagag agtttagtga ttcggctatt atacggtact
    14401 tttgaaacac cccatcgttg ctttagttct cgagattttg caactatttt acagaaaacc
    14461 gtcagacgtg gattatacct tttcagcgga ccagtcggat caggcaagac ttctctaatg
    14521 tatcggttgg ctttggaaga aaaattgcaa gtgattacta tcgaagatcc tgtagagata
    14581 gaagaaccgt tttttctgca gctacagatc aatccgaaaa tagcacagac ttatgataca
    14641 cttttgagac tcgcattacg gcatcgtcca gacttgctaa tcattggcga gataagagat
    14701 gaatcaactg cacatgctgc ggtaagagca gcactaacag ggcaccgggt ttttgcaacc
    14761 gtacatgcac gcaatcttga aggtacattg gtcagaatcc atgaactgac aaagaaaaaa
    14821 gaagagctat ctgaatgttt agctggtgtc atttatcaag aacttttgga agatgccaat
    14881 caccatcctt ctgttttatg gagttatcaa tttatggagg aagaatcagt aaaaaaatca
    14941 tgggaggaaa gttatgaaga agctcaggaa aatatttggc agtcagaact attctaaagg
    15001 attaacaaga agccagcaaa accagtttgc acaaaccatg ggagaactgc ttttatctgg
    15061 ttttagtctg caagaatccc tttatttatt actcacgatc cgttcgtttc cacctgttat
    15121 tttggcaaat atccaacatc agctaaagga agggcaagcg tttagtgagg tactttcgca
    15181 aataggatat ggagcagagc aactggtaca gatcgagtta gctgaacgtc atgggaatct
    15241 gccgacaact ttgttggaaa ttgccaaaca gtttcggctt gttgaaggat ttcgcaatga
    15301 tttgaaaaag ctgcttgcat atccgatgct attgctcacc tttttgctag gtatcttgtt
    15361 tagtatgcgg ttgttcgttt tgcctcagct tattggttca ggaatggtca tgcaagagca
    15421 ttggggtatt cagctgatac aagtctttca ttggtatgtt ctactattca tcctagcggt
    15481 tactctattg gctttactag taaggtatcg tctgatgaag ttgtctcctg ttgatcagag
    15541 tgaatggata agcagacaat tattgattgg accgatatat tccttgtatc aatcggctta
    15601 tttgtcacta gagattggaa agctttttca tgaaggtttc gaattaaggc aaatcatagt
    15661 ctgcttaaag gaaacgaaac aagaaagtct gattcagcat cttgcctcta agttgattca
    15721 aggattggag gcaggtatgt cattggctga gcagttccag aattatcgtt ttctatcaga
    15781 agaattcagt aaaattgttt tacagggaga ggcaaaggga agtttaggta aagaactgat
    15841 tttttacagc gaatggacaa gaaaacagct tttcaaacgt cttcatcact ggatgcattt
    15901 tattcagcca atcatttttt tgggcgtagc ggctttgatt ttattagttt atgccgctgt
    15961 tttattacct gtttacggaa gcatagagga ggttttgcca tgaaaaagag aaaaatatct
    16021 tattatagcg gttttacatt gatcgaaatg ctaatcgtct tactgatcat cagtgtatta
    16081 gtgttgttgt tcgtccctaa tttgtcgcgt tataggaatc atgtagacca agaaagtcgt
    16141 gaagcgatca tccagttggt agacacacaa aaagagctct atgcgcttca aaataatgga
    16201 agagttccta ctgtggagga attgttgaat gaaggctata tcaaacgaga acatgcagaa
    16261 atctatcagc ggccttgaag gtaaggtttt agcatcagga tatacgttgt ttgaatcact
    16321 cttactgatt ttattactta caacgatcct ttcttttcca gttctcgcat tttctgcatg
    16381 gaagaatgaa ttggcagtct atcaattttt cggccaattt gaaaaacgaa tctattctac
    16441 gcaaaaaatc gctattgtga atcagatcca aacaggcttt tattggaata gtgaagagaa
    16501 tcaaatcatt tttcatgttc cgaatccaga taaaataaat tgggaagtat tagatattcc
    16561 tgatgagatt accttgaaac gccatgcttc tattactttt gctgctagaa ccgggaatga
    16621 aagttcacta aaagcttatc aattttattg ggaagaaaaa gagcggacga ttacgtatca
    16681 attccagata gggagtggtc gctatacaaa aagaattgaa taaaacagga tttgttttgt
    16741 tggagtccct tacagcgctt atgatcgctt ctgtctgtgt ctacttagtg agctttggcc
    16801 agctgttttt gcttcaggca gaaaagaaaa gtggggagga actgctattt attcgaatga
    16861 tttatgaaga tatcaagacg cagcggatgt atcacaaaag accagagcga agggaagaaa
    16921 tgatcccata cgatatccaa attgtcgata ataatggagt aatcgaaaaa gtgtttgtca
    16981 atatggagaa agaagcgatc agtattgaaa aaacaagtaa ttccagcatt tacgctgatt
    17041 gaatgtctaa ttggactgat gatattgagc agtctattgc tcacattcaa tcttttgatt
    17101 cagcaaacca tccaagtaag tgaatttttg cagcgtaaag atcaaaaaga gtggctaata
    17161 tttttagcac aattagaaga agaactcaag agcagtcaca atgtctctgt gaaaaatcag
    17221 caactgcact acacgatcga ggataaacag tatatcatcg aaagatatca ggcaatgata
    17281 cgtaaaagaa gaacttccgg cggacatcaa cctatgttaa caagtatcac tgagcttcaa
    17341 ttattggaaa aagaacacac aatttctttt tatgtacact ttgaaaatgg agaagatgga
    17401 tatgccatat ggacaaaaaa cgatcagtag aaaatgttat aagggctcta ttttattttc
    17461 tgtcttgctt ttatttcttt tatgtacgtt tttattgatg gcagcattag aaagctaccg
    17521 tttgtcaatg gatcttaata tacgaatcaa aaattattat atagcaaaaa taatgaagca
    17581 gatggcttta tcggaacagt ctacgcttgc cgaaagttcg gaaggagttt tttactacac
    17641 aactggatct gtaacatatc agtgggtaca acagtcccta ttcttagagg tggaagtctc
    17701 accgtttatc tttcggttca cagaagaagt aaaaaatgat acagatacta gtacagaatg
    17761 atggaatgtt cgtgaaaacg ccctcttttc tgttataaca ctgtttttaa taaaaaaatg
    17821 tttgccgttt cacaaataaa aaacagtgaa aacgattgaa attttgtcaa ttgttcgata
    17881 gaattaaaca ggtgaaaaaa ttgttataat atatctagaa atgaggtgca ccatgttacc
    17941 agaaaaaatg gaacaagggt ttaatcaaaa cctggaagct attcagcttt tacagaatgc
    18001 attgggaact tcctttttag aagcctatgt cgaaaatgca gaaaatttaa tagatgatta
    18061 tcaagtacgt gtggtggatg gagtgccgac aaaagagaca acgcaacgga tcacagctct
    18121 ttatgaagag ttgaagaaac tttctttcga gccagaagaa tggcgcagac tgtctcaatt
    18181 acttttattg aagggcagcc agacagaaca tttgcaggcg aaccatcaac tcactcctga
    18241 tagtatcggt tttttatttg tttttcttat tgaacaacta tacacaaata aaaaagcacc
    18301 ggttaagatt ctggatattg cggcaggaat gggcaacttg ttattaacag ttcttttaaa
    18361 cctatcgaat gcggggtacc aaacagaagg aattggtgtg gatattgatg atacattgtt
    18421 ggctgtcgca gcttctacaa gtgatttgac acaagcaaat gttcaatact ttcatcaaga
    18481 cgggttgcag gaattattaa tagatcctgt cgattttgca atcagcgatt tgccaatcgg
    18541 ttattatccg aatgacgaaa aagcaaaaga gtttttaaca agtaccgaag aaggccatag
    18601 ttatgcacat catttattgc tagagcaatc aatgaaatat gtgaagccgg atggttttgg
    18661 tttgtttttg atgccgagtg gatttttaga aacggatcaa agtgaagaaa tcaaaaaatg
    18721 gtttaaagaa gaaggttatc ttcaaggaat gattcaattg ccagatgaat tgttccgtaa
    18781 taaacaatcg caaaaaagta ttttgatctt acagaaaaaa ggaccacaag cacaacaagt
    18841 aaaagaagtc ttgcttgtga aacttgcttc attaaaagaa ccagagaagg tgacggaatt
    18901 tttcaacgag tttaaaaact ggaaatcatc tgctctgtaa tcattcaacg agaaggagag
    18961 tcatatgtct aaaacaattg caatcaatgc tgggagttca agtttgaaat ggcaattata
    19021 tcaaatgcca gaagaaaccg tagttgcgaa agggatcgtc gaacgtatcg gtttacaaga
    19081 ttctattttt accatcaagt acggcgataa tcaaaaattc gaacaaatca tggatatcga
    19141 aaaccacgaa gtagcagtaa aaatgctgtt agatcagttg attgaactgc aaattttaag
    19201 ctcttatgat gaaatcaccg gagtagggca ccgtgttgtt cacggaggag aaacttatgg
    19261 ggattcagta gtgatcgatg agaaagtaat ggaccgcatt gctgaattag cagaatttgc
    19321 tcctttgcat aatcctgcaa acttaatggg gatcaaagcg tttaaaaaga ttttacctga
    19381 cattttgagt gtggctgtat tcgatacatc tttccactca acaatgccaa agcaaaatta
    19441 tttatatagc ttaccggtgt cttattatga agatttcaaa gtaagaaaat atggcttcca
    19501 tggcacaagt catcgttatg tgtcggaacg tgcggcaaaa ttattgaaca aaccgatcga
    19561 agaactaaaa atcatcactt gccacttagg aaatggtgta tcgatcacag cagtcgatgg
    19621 aggtaaatcc atggatactt ctatgggatt cacaccatta gctggggtga caatgggtac
    19681 acgttcaggt gatatcgatc cagctgttct cccatattta atggaaaaat tagagattga
    19741 tattgatgaa atgatcaatg ttttgaacaa gaaatctggt ctgctaggcc taacaggatt
    19801 gtctagtgat atgcgtgatc ttgaaaagaa ctatgaaaaa gaacatattc gtttagctta
    19861 tgacattttc gtggaccgca tccgaaaata catcggcggt tatgtgacaa cgatgaatgg
    19921 tgttgatgca attgtcttta ctgctggtat cggcgagaat gacggacatg tacgtagtga
    19981 aatcatcaaa ggtatgtctt ggtttggttg tgaaatcgat ccagcgttga atgaattgcg
    20041 tggtgaagaa gtagatatct ctacaaaaga atcaaaagta agagtattag tgatcccaac
    20101 agatgaggaa ctaatgattg cccgtgatgt ggagcgtctg cgcggctaag ccaaagcatt
    20161 cgttaggata aaagatgaaa cgcatgcaag agggaattct tgcatgtgtt ttttttgcgg
    20221 agaagaccgc aaaatggtaa tttaacttca atttcccttc ttttttacag gatcttctta
    20281 gggaattttg cttggaaaag tggtcaaaag ggaaaagact ggcattttat ttattgattt
    20341 tcaggaaaat cccaatattt tattttcatt catctttata agggacatta catatgtaaa
    20401 aagaaaaaac atttttagat cagcctcgtg ggctgtcgac tttattcttc gctttatgtt
    20461 tagctagaaa accgatccga aacattcatt gatcgaataa taaaaacttg attttccacc
    20521 tgtactttgc ctgaatcgtg aaagcacagg tatgaaaatc aagttttttg ttgcgaaaaa
    20581 acgtcctagt caatcagttg gccgagcggc tggcggctga tctgctcctg atcaataacg
    20641 agtgcttctt ggaagtgttg ctgcaaaaag tagcggtcat ggctgactgc taggagcgtt
    20701 ccttgatagt cttgcagcat ttcttcaatt tcttctcgag catagctgtc gaggtgattg
    20761 gttggttcat ccaaaatcag gacgttgatt ttttctaaaa agagtttcag caacgccaaa
    20821 cggatttttt caccgccgga taaatctttg atccgtttac ccacatcgct ttgataaaag
    20881 ccacttttgg ctaattgccg tcgagcgact tcttcgtttc cagtcaatgt gatggcgtaa
    20941 gccagcaaac ggctatcggg atcggcaaac tgcagctgct gcggcaaata accgatttgc
    21001 aagctactac ctaatttgat ggtgccaccg taaggctttt cctcaccgag taataatttg
    21061 agtaaggttg attttcctgc accattgtcg ccgatgatgg ctaaatgatc tccacgatag
    21121 actgcaaaac tgctgtcttt gaatagtact tgatcagcgt actgctggtg caagttttga
    21181 atgatgaaaa cttctttgcc agattttcca ccattagaca agctttgcag ccgatttttc
    21241 gggggaggtg gcggtttgac gagtgtcagt ttcgccaggc ggcgttccag ttctttggct
    21301 tttttgaaga aggactcatt gtctccttca tgtgcccact gacgaaaacg acgaatcatg
    21361 actttcaacc gctggacttc tttttgctgc agttcgtaat tttttgtcag ctcagccaag
    21421 cgagcttctt tcaagactcg aaaacggctg tagtttccgg gatactcaat caatgcacct
    21481 tcttccagtt cccatgtttt tgtggtgact tgatcgagaa attgccgatc atgagaaacg
    21541 accagaaccg atttttttgt attctgtaaa tagttttcca accagcgaat actgttaaga
    21601 tctaaatgat tggtcggttc atcgagtaaa agtaaatcgg catcggctgc taaaattttg
    21661 gctaaagcga ctttaactcg ttcgcctccg ctaagttctg ttaaccgtgc ttcctgacgg
    21721 tgtggaatcc ctaagccttg caagatcgct gcaatccggt cttctaatac gtaaccgcct
    21781 agttcttcaa agcgatgctg cagctcaccg taacgggcca gacacttctc taagtttgta
    21841 tctggttctg tcatcaatgc ttcgtagcga ctcatttgct gtttgaggtc ctgtatctca
    21901 gcggcagaat ggagcaagta gtggttgacg gtcgcttcgg aaactgtaag ttcttgttcg
    21961 accgtcccga tctttaagcc ttttttgcga ctgataacac cgctgtcgac accttctctg
    22021 ccggtcaaga tttgtaaaaa ggttgatttg ccagttccgt tgataccgac taaggcaatt
    22081 ttttcaccag cttcaatttg acaggataaa tcctcaaata atggattccc gccgattgtt
    22141 tttttaatag aaattgcttg tatgatcatg atctctctcc ttgagaccac tcaaaaaggc
    22201 catggttatc catggcctgt gttatttaaa ctcagattat catgagaaaa ataccttgag
    22261 atggccattg attttacgtg aattcaactg ttttggacaa acttgtcccg tcaacagcaa
    22321 ctgtaaaacc aattgcatgg ctaaatgcga tatggtatcg ttggtaattt tcattacttg
    22381 ttattttagt catgcgcatc atagtatttt ccctccttcg tgtagttgtc ttttccagtg
    22441 tacctgaaag tgtcagaaag ttcaactagc gctgacattt acttaatatt tatcgatgtg
    22501 taattctgtc agagagcttt ttttatctga ctgagggtaa tgtctcgtgg accacatcat
    22561 tgtattctga gctaaaccag cgttcaggcg aaatcatatg gtgtttgata aaaaactttg
    22621 tctacatgac ttccttttgc catttgctta ataccgttgc attaaacagc tcttctcttt
    22681 ggaaatctca ccaacatcgc gttcaggagt atcgttgtgg ttgcaatggc aagcggtagc
    22741 ctttcatcaa ttcttgaatg atttaccgaa tgtagcactt gccttctcgc ggtacccgaa
    22801 cccgaaataa aattttagtt tggcgataaa atcggtatcc gccatcgata cttcatattt
    22861 tttcgtatca gattcatcgg aaacttccac attgacgaac caataagctt tggcatgctt
    22921 aggtcgtttt aaaccacacc agggcgacta atcgccctgg tgttcacttt tttttatttt
    22981 acttgaactc attgactgtt ttccctttat tttaaacatt ataaagaccg atgagtgctt
    23041 gccgcgtctt ttgtttttat cacggttttt tgtgcaaaaa aacctgccga tagttggcag
    23101 gtcgtctacg tgttaagctt tggtgtggtc tttagctggc aattggtttt ctaaatcagt
    23161 tcggacaaca agcacatcgc aagctgcgtt tctaataaca tattcagaaa cagaaccaat
    23221 aaataaacgt tctacagcat tcaatcctgt ggctcctaac ataatcaaat ctacttgatt
    23281 atcttctggg atttctctgg caataatttg ttttggtgag ccatattcta cgacagaggt
    23341 tacattattc aagccagctt tcttcgcatt gctttcataa tctgccaatg tttgctttgc
    23401 catttcagta gcttgttctg caagcattcc atcaaaggat gaaacggttt ggaaagaacg
    23461 tgtgtcaatg acatgtgcta atagaagttc tccgttattt cggatagcta cattgaccgc
    23521 ctttttaaaa gctaattcag cttcatcaga accatctacg gcaaccatga tttttttgta
    23581 ttgttgtaac ataagcattc actcctcaag tcaatcgtat tgtactcttt tattgtagaa
    23641 cactttaggg aaaaagagaa ttatttactg ctttggttca gcaatttttt ttgcaaatcg
    23701 gatactgaag gtggcagaaa caataattac gatcagtaaa aagaccaagg caataaagcg
    23761 ttgattgaaa aaagctgtta aaatacccat tacgcctaaa acagcatatg cagctccgta
    23821 aaattgtagg aatccttgat ttttatcatt tttgttgatc aatacaaaaa agatatcctg
    23881 tttattaaat aaataatagc taacgaataa taatactaaa gtggcgataa tcattaaaat
    23941 cctaatcatg aacaaatcct ccaaaataag caacaaatag aaaaagcaat ttgccaagag
    24001 caaattgctt tattctttaa aagatggtaa tctccgttaa tgccgttgtt tgtcctgtag
    24061 tattgatccc gcgaattcaa gcaggtgggt cccatggtcg tagcttcgaa ctaccaaatg
    24121 ataaggcatg ttaccagcag tgacacaaga cgggtcccaa gatatcaata aaaatgttcg
    24181 gtcaacacac aaagaggaca attcgaacat cacagatttc ccacctctat agtagcatat
    24241 gaatttaaaa agagcaatga gagagctcgc agaaacagaa ccgttttctt gtctagtttt
    24301 ttggaggatg ctttttccac tcttttatac ggtaatactg ttgacccaga gcctgttcat
    24361 atttccctgt atcttttggc tgataatact gagcattctt cagtttatct ggtaaatatt
    24421 gctgattgac ccaagcctga tcaaaatgat gaggatactg ataacccacg ccacggttga
    24481 gtgatttcgc acctttgtaa tggctatctc tcaaatgatc aggaacatct ccagctttgc
    24541 cctctcgaat atcagcaagt gctgcatcta atgccatgta ggcagaattg gattttggcg
    24601 acaagcaaag atcgacgacg acgtctgcta gtgggatacg tgcctcaggc aatcccaatt
    24661 tttcagcagc taatacagcg ttcactgtac gagccgcagc agcaggatta cctaaaccta
    24721 tatcttcata accgataacc atcagacgcc ggcaaatact tgccagatca cctgcctcaa
    24781 ctaaacgggc gagataatga agtgcagcat ccacatcact tccacgaatc gatttttgaa
    24841 aagccgaaat aacgtcataa tgagcatctc catttttgtc atgggtaaga gcttttcttt
    24901 ggacacattc ttcaatgatc gacagtgtaa gatgaatcct tccttcttta tctgaaggag
    24961 tcgatagtgt agccagttcc agcccattca atgcactccg caaatcgccg ttcgttgcac
    25021 gcgaaaggtg aagaagagca tcttcgtcta actggattgc ttgttgtcca aggccgcgtt
    25081 ctttatccct taaagcatgt tcgactgcca actggatgtc ttgttctgtt aatggtttga
    25141 cttcaaagat ctgtgtacgg ctgcggatcg ctggattgat ggtaatataa ggattctcag
    25201 tagtcgctcc gatcaagatg attcggccac tttctaaatg aggaagcaga aaatcctgtt
    25261 ttgttttatc taatcggtgt acttcatcca ataagaggat cactgtacca ctcatttttg
    25321 cttcttccgc tacaacttgt agatcctttt ttgaatctgt agcggcgttt agcatgcgaa
    25381 atgcataatt agtagagccg gcgatcgcac ttgcgatact cgtttttcca gtaccaggag
    25441 gtccatatag aatcatggaa gagagcatgc gagcatcgac catgcggcgt atgatttttc
    25501 cttccccgac tagatgctgc tgaccaacga cttcatcgat cgttcgaggt ctcatgcgat
    25561 aagccaatgg ctgttgcata ggattttcct ccttcttgtt tttacgtccc ttaattatat
    25621 catatttagc aagatgccta gaaagaacag ccttctgttg ttttgttttc atagcttatc
    25681 caactaatat tgtgtatgat aaagtaggtg agaaaaatga cggataaaca aaagatagat
    25741 gaattttttt ggaataaaac gacgccagaa gtggcacggg atttattggg gatgtatttg
    25801 gagcatgaca caccagaagg aagattagct ggatatattg tagacgcgga agcataccta
    25861 ggtccagaag acgaggccgc ccatagctat ggtttaagaa gaacaccgcg tgtgcgggca
    25921 atgtatgaaa aaccaggtac gatctacctt tacacgatgc atactcatcg gattttgaac
    25981 atcattactc agccagaagg gattcctcaa ggagtaatga tacgtgcaat cgaacccgcc
    26041 gcaatgattg atcaaatgag taaaaatcgt ggcggaaaaa ctggtccaga tatcagcaac
    26101 ggtccgggaa aattagtgga agcattagca attcctcaag aactttatgg tcagtctata
    26161 gcagatagtt cgttacgctt agtttttgag aaaaaaaaga caccaaaaaa gatcaatgct
    26221 ttgcctagaa tcggtatccc aaacaaaggt gtatggacag aaaagccgtt gcgttttgtt
    26281 gtgtcgggaa atccttatat ctctttacaa agaaaaaacc aaatcgagaa agattggggt
    26341 tggaggaaag aaaatgaaaa agaaggatct attaacatat ttagatgaaa taattgaaaa
    26401 acaagtgaca gactatgatg tagctttaga ttgggataca aaaaatcata cgatcgagat
    26461 cgttgttcgc ttgtttgcag aaaataaagc acaatttgag attgatgatg cagaagggat
    26521 cgtttcgcaa gaaccaatta tcgaatttga agacggcgta cttcttttta atcctcagaa
    26581 atctgttttt gatgaacgca attatctagc agtaatccct tatgaaggaa aaaaagggtt
    26641 ggcaaaatca gtagctgatt ctttagtgga atatctaaat gaagtattag ctcaagggca
    26701 aagcgatttg cttgattttt tggatgaaga cgatgacgaa gctgtattcg agcttcactg
    26761 ggataatcag caactagcag aattagtaga agtaaaacag caaaatgaag cagatactta
    26821 tttaccgtac ccaagttatt aaggagtgac agatatgaaa tggaatgaag taaaagtaga
    26881 aactgaaagt gaagcagtcg aagcagttgc taatattttg atggaggcag gggcgagtgg
    26941 tgtcgcgatt gaagattctt tagatgttga acattttcag tcggatcaat atggtgagat
    27001 tttagataaa aatgatttta catcgctgaa agaaggcgca ctagtcatgg cttattttcc
    27061 ggaaacgact ttcttaccgg aaatcttgcc ttttatcaaa gatcgtatca cacaattacc
    27121 tgagtttggt ctagctattg gaaaaaataa agtaacagtt agtgaagtag aggaaagcaa
    27181 ctgggcaaca gcctggaaga aatactatca tccggtgcgt attacgcgaa tgctgacggt
    27241 tgcgccaagc tgggaaaact accagacaga agatcctcta gaaaaaatta tcacactaga
    27301 tcctggtatg gcatttggca caggcactca tcccacgact tccttgacat tgacagcact
    27361 agaaacagtc ttgcgtggtg gtgaaacatt gctagatgtg ggaactgggt cgggcgtgct
    27421 aagtattgca gcaaaatatc ttggtgcaaa agatgtctat gcctttgatt tagacgaagt
    27481 agccgttcgt tcggcgaaag aaaatatgga tatgaatgaa atagccaaag atgtccatgt
    27541 atcagctaac gatcttttga caggaatcga gattgaaagt gatgtaatcg ttgcgaacat
    27601 tttagcagat atcatcttat tgatgatccc agatgcttgg cgtttactga agcaaacagg
    27661 cacgctgatc gtttcaggaa tcattgaaga gaagaagcaa atggttctgg atgccatgtt
    27721 agaacaaggg tttatcgtgg atcaaatttt ccagcaaaaa gactggtatg caattatttt
    27781 gaaaaaacca gaggtggaat agatgcagcg gtatttttta aaagaatcat atgaatcaaa
    27841 agactatttt gttttagaag gggaaaacta tcaccacatt gtacgggtta tgaggatgga
    27901 acccgaggat gaagtttttt tggcattcaa tgatcaaata gccattgttg cagaaatcac
    27961 ggagattact gaagaggctg tttatctgaa agaaattaaa aaagaagaaa atcaaaagga
    28021 actgccaagt tcgattacca tagcgagtgg ctatcctaaa ggggaaaagc tggattggat
    28081 cgttcagaaa tccactgaat taggagcgca agcttttctt ggtttcccgg catcagcctc
    28141 tgtcgttaaa tgggatgcaa aaaaacgtat gaaacgacaa caacggcttg aaaagattgc
    28201 tcaagaggca gcggaacaat cccatcggca gatcgtgcca tcagtagagt tattggaaac
    28261 gaaacaagat ttatttgagc ggctagatga ttatgacgtg gtcttggttg cttatgagga
    28321 atcagcaaag caaggcgaaa aatcaaatgc agccaaaatt cttagtgaaa caaaaccaga
    28381 tagtcgaatc ttagctgtct ttggaccaga aggtggatta tcccgcgatg aagtcgatta
    28441 ttttgtagaa cacaaaggga tactttgtgg attaggacca agaatccttc gtacagaaac
    28501 agcacctctt tatttattaa gtgctgctag ctatcaatgg gaattaatga atccttcttt
    28561 cagctaacgt tcttcattaa taaaagagta tcgacagaaa gaattgaaaa aatagtcaac
    28621 aatttgtata atagaaacaa ttatttatac aatggatacg aaaaatcgtt tgaaaaagct
    28681 tttaaaaagc gaacatttcc gtaaaaaaac gtataactgc acggattttg ggacaattat
    28741 caaacagata tttgtcccga ttcccgtttt accgaaaaaa gaaaggggga tcgattcctg
    28801 tgacaaaaga agaaatttta acgggacccg gtgtcataaa gctcgttagt caatacatgg
    28861 gtcccgaaca tgtagcattt gttgagaaag catgcgaata cgcgactgct gcacatgacg
    28921 gacagtttag aaaatcaggc gaaccctaca ttattcatcc tatccaagtc gcaggtatat
    28981 tagcagattt aaaaatggat ccccatacag tggctacagg cttcttacat gatgttgttg
    29041 aagatacaga aatcacttta gaagatctga gagaagaatt tggcgatgac gttgctatgt
    29101 tagtggacgg cgtaaccaaa ttagggaaaa taaaatataa atcccacgaa gagcagctag
    29161 cagaaaacca ccgaaagatg ctgctagcaa tggctcaaga tttacgagtt atcatggtca
    29221 aattagctga tagactacat aacatgcgta cgttgaagca cctgcgagaa gataagcaaa
    29281 gaaggatcgc tcaggaaact ttagaaatct atgcgcctct tgcacatcgt ctagggatca
    29341 gccggatcaa atgggaatta gaagatacag cacttcgtta tctaaatcca aaacagtatt
    29401 accgtatcgt ccacttgatg cagacgaaga gagaagaacg tgaaaaatac gtaagtggta
    29461 ctgttgaaga tattcgaata gcgacagaag agctggggat ttttgcagaa atctatggac
    29521 ggccaaaaca catttattca atctatcgta aaatgaaaga tcagaaaaag cagttcaacg
    29581 aaatttatga cttgctagct attcgagtga tcgtagattc aatcaaggat tgttatgctg
    29641 tattaggagc aatccacaca aaatggaaac caatgcccgg cagatttaag gattatattg
    29701 ccatgccaaa agctaatatg taccaatctt tgcatactac cgtgatcggt ccggcaggaa
    29761 atccggtaga aattcaaatc cgaacacagg aaatgcatga aatcgctgaa ttcggggttg
    29821 ctgcacactg ggcctataaa gaaggaaaaa atgaaaaagt agaaccagat ggtatgacga
    29881 aacaattaag ctggttccat gagatactcg aacttcaaga cgaaagctat gatgcttctg
    29941 aatttatgga aggcgtaaaa ggagatatct ttagtgataa agtctacgtc ttcacaccaa
    30001 aaggagacgt tactgagtta ccaaaaggat ccggaccatt ggactttgca tacagtatcc
    30061 atacagatat cggtaacaaa accactggtg caaaagtaaa tggcaaaatg gtgcagcttg
    30121 attacaaatt gaaaaacgga gatatcattg agatcatgac ttctccaaat tcatttggcc
    30181 caagtcgcga ctggttgaaa ttagttgcta ctagcaaagc aagaaataag atcaaacgtt
    30241 tcttcaaagc ccaagatcga gaagaaaatg tgatcaaagg ccacgaatcc gtggtcaaat
    30301 gtattacaga tctaggattt acgcctaaag atattttgac gaagaacaaa ctgcaagaag
    30361 cactcgatcg ttttaattat caaacagaag atgatctcta tgcagctgta gggtatggag
    30421 aagttagccc cttgacgatg gccaatcgtc tgactgaaaa agaacgtaaa gaacaaaaaa
    30481 tcgagcagca aaagcaagaa gcagaagaaa tcatgaatca gccgaaaaaa gaacctgaca
    30541 aaatgaaagt acgtcatgaa ggtggcgttg tcattcaagg ggtagaaaac ttactaattc
    30601 gtatcagtcg ctgctgtaat ccgattcctg gtgatgatat cgttggttat atcactaaag
    30661 gcagagggat atccattcat cgtcgagatt gtccgaatgt tcagcctgac aaaccaaatg
    30721 tagcagaacg tttgattgaa gtcgaatggg aagatacatc gaatacacga aaagagtatg
    30781 atgcagattt ggaaatttac ggctataatc gttcaggctt attgaatgat gtacttcaaa
    30841 cagtcaatgc gctaacgaaa aatctcaaca gcgttgaagc acggacgaat aaagataaaa
    30901 tggcgacgat ccatttgacg gttggtatcc agaatttatc ccacctaaag agtatcgtgg
    30961 ataaaatcaa agcagtacct gatgtctaca gtgtacgccg gacgaatgga taggaggaca
    31021 gatatgagag cagttgttca acgggtaagt aaagctgctg tgtcagtcga tcagcaagaa
    31081 attggaaaaa ttggctacgg cctacttgtt ttattaggca ttcatgaaac cgatacgcaa
    31141 aaagatgtgg actatctggt aaaaaaaatt gcacaaatgc gtatttttga agatgaacaa
    31201 ggaaaaatga atattagtgt agaagatgtg ggaggacaaa ttttaagtat ctctcaattc
    31261 acactgtttg cggatacgaa aaaaggaaat cgaccaagct ttgtggaagc cgcacgacca
    31321 gaaacagcta ttcctttata cgaatcattc aatgaaggaa tcagaagtcg cggcatcaca
    31381 gtcgctaccg gacaattcgg agcagatatg tcggtttctc tcgtcaatga tggacctgta
    31441 acgatcatta ttgattctaa aaacaaataa agtaatctgg ttttcactag taaaaactat
    31501 gaaacacgtc gcttaagtta gactgataaa ctctaactta agtggctttt ttgtctgcaa
    31561 aaagcgcttc ttttgtcagc agtcggaaaa aaagttaagc ttaaattata caagttattt
    31621 tttataggag gttgctgaag atgaaagaag taccagtagt agatatcaaa atcacagatt
    31681 taaaaaaatt gtatcaaaaa ggatacaaca tgttggagga gttacgccat gaagcggacg
    31741 ctcccgtcgt caaagcaaag attttcaata aagaagctat cacgatctac ggatcatcag
    31801 cagcaaaagt attttatgat ccaaggaatt tcaaacgaaa aggtgctatg ccaaaattag
    31861 tattgaagac actttttggt caaggtggag tacagacttt ggatggagct gctcatcacc
    31921 atcggaaaaa tatttttatg gatctaatga caccggaaag aatggaagat tatcatcgta
    31981 tcttagataa gaatctgaca caagcacttg aagcacagca tggtcaattt gaactatttg
    32041 atttaagtaa gatggttttc tttacatcta tttgcgagtg ggcaggtatc aatttatcag
    32101 cgatttctaa agatgaggtc gaaaaattag cagaatatca aatctctatg atcagcggaa
    32161 cgtttacttc tccgattgat cacataaaag gtgtcgaaaa tcgcaaaaaa tcagaaaaat
    32221 gggcgcaagg cttgattgaa gaagctcgac aaaatcctgt ggctggaaaa gaaaatgtgg
    32281 cattatatgc ttttgccaat gccacagatt tagatggtca gcttttacct ctggaagtgg
    32341 cagctgttga attattgaac atcatccgtc caacggttgc tctaactgtg tgggcggcat
    32401 tgatgggaca tgcacttttc agtagaccag atttgtatca gcaattaaaa aatgactttt
    32461 cgacgttaca agatccgttt attcaagaaa tgagacgcta ttatcctttc ttcccaatgc
    32521 tacctgcgat ttcgctgaaa gaagtagaag tagatggtta tcgtatacca gaaggcagtt
    32581 gggttatttt agatttatat ggaacagacc atgatgaacg aacagttgaa gcgccagatt
    32641 cctttatgat caaacggtat gtagggaaag caaaagatat ttcctataaa gaagaatatg
    32701 agatgattgc acaaggcggg ggaaattttc gacaaatgca tcgctgtgca ggagaatgga
    32761 tcactcttca tagtctacgt gtgttttccg atcagctagt aaataagttt gagttctctg
    32821 tacctgaaca agattggacg attccattca atcagtttcc gacttatccg aatagccgag
    32881 cgctacttta caagaattag attagcataa acttatcgaa aaaaaggaag atcaaacagt
    32941 gctgatcttc cttttttcat attactataa attgataagg tcaattgatc aaaatccacg
    33001 aaatgcttca tcaatggttt gataatcttc attggataaa tgcaaatcta aagcttggac
    33061 attgtcagat acttgctctg gacgcttagc tccaggtata actacagaca ctcgtggatt
    33121 cttcatgtac caagctaaaa caagttgcgc aggagtggct tggtatcttt tagcaatggg
    33181 gcgaagtaca tcgacagcgg ttaaaatttc tctgaaacgt tctccttgga aatctggatt
    33241 tctttttcga ggatctcctt caccaaattg tttttcctca ccaagttcat attttcctgt
    33301 cagcaaaccg gaagcaagag gaaaataggg aacaaaactg attttgtttt tttcaagata
    33361 agggaataat tctttttcag cctgccgatg gatcaaactg tatttatctt ctactacatc
    33421 gacatatcca tctgcattcg cttctttcaa ttgttctaac gtgaagtttg acacaccgac
    33481 tgctcggatt tttcctgctt cttttaattc gtgcaatgta gcaactgatt cattttttgg
    33541 tgtgctttca tccggaaagt ggatataaaa aatgtcgatg taatcagttt gcagacgttt
    33601 tagtgcatct tccaccgatt gtttgagaaa ctcaggagaa ttatcaaatg ttcgcccttt
    33661 atttggtata tgagcagctt ttgtagcgat gacgacacgt gagcgatcat attctttttc
    33721 cttcagtacc tcgccaatca gttcttcgga acggccgttt ccgtaagcat aagcggtatc
    33781 gatcaaattg atcccgctat tcaaagctgt acgaactact tgttttcctg tctcatcttc
    33841 caaaccgtca aaaagattat gtcctccaac ggcatttgct cctaatccaa gctgttctgc
    33901 gtagacttgt gaatgtccga ttcttatttc tgccatagct gattcctcct ttttgtctag
    33961 tctaaaacaa aataccaaaa agctgaacta aaacgttttt gtgaggggaa atagtcagat
    34021 atctcttgac tttgagactg gtttttagta ggttataagt aatatcgaat gtcaatgaaa
    34081 gagcgagtaa gtttttgaaa ctttacaaga gaggatcatc gaggctgaaa atgatctaaa
    34141 gtttcattag cctaaagaca ctctggagat ggacgagtga aaagccgtcc cgcgtacgag
    34201 cgttattcgt aagaggaaag agaaatcttt caaaattagg tggtaccgtg tatgaatttc
    34261 attcaccctt gttcatgatg aacaagggtg atttttttat ttacatagct aagaaaggga
    34321 gagaaaacta tgagtttcca aagaccaaaa ggaacaaatg atattttgcc aggcgaatca
    34381 gaaaaatggc agtttgtcga agaaacagca cgtttattat tcagagatta tcagtataat
    34441 gaaatgcgta caccgatttt tgaacactat gaagtgatat cccgaagtgt aggggataca
    34501 acggatatcg tttcaaaaga gatgtatgat ttttatgaca aaggggaacg ccatgtgacg
    34561 cttcgaccag aaggtacagc accaatcgtt cgttcttttg ttgagcataa attgttcggc
    34621 ccagagtatg cgaaaccgtt caaaactttt tatatgggac caatgtttcg ctacgaacgc
    34681 cctcaaaaag gacggttacg tcaattccat caaatcggag tagaagcatt tggatcagaa
    34741 aaccctgcaa ctgatgtgga gagcatggtg atggcacttg atttcttcaa acagttgggg
    34801 atcacgcaaa tccggctagt catcaattca ttaggtgata aagaaacgcg tcaagcctat
    34861 cgtcaagcat tgatcgacta tcttttacct tttgaatcag agctgagtga agactctaaa
    34921 cgccgccttc atgaaaatcc attacgcgta ttggacagta aagacaaacg agatcaaaaa
    34981 tttgtggcag aagctccatc tatcttagat tatctaagcg agcctgctca aaaacatttt
    35041 gataccgttg tttccatgct ggatgcattg gctgttcctt atgaaatcga cagtaatatg
    35101 gttcgcggac tagattatta cacacatacg atttttgaaa tcatgagtga cgcaccaaaa
    35161 atgggggcac aagcaacgat ttgcgcaggc ggacgttatg acaatctagt ggaagaacta
    35221 ggtggtcctt caacacctgg cttcggattt gcaatgggta tcgagcgatt actcttgact
    35281 atggaggcag aggaagtagt tatccctgca tttaatgagt tggatgctta cgtggtcgca
    35341 ctcggagacg aaacaaatat cgaagcattg aaagtggtcc aagcgattcg aaactttggt
    35401 ttttcagctg accgcgactt catgaaccgt aaagcaaaag cgcaatttaa gacagcagat
    35461 aaagcgaatg ccaaattagt attggtgatc ggtgaagatg agcttgctag tcaaacgatt
    35521 aatgtcaaag caatggcaag ccgaaaagaa aaaagttttc cattagaaga gatatatgaa
    35581 cattttgatg aagtctatga tgaaatgact ttattcgagt aggaggaaaa aaataaatgg
    35641 cacaaagaac gatctattgc ggattagttt ccgaacaaca attagaacaa acagttacat
    35701 taaaaggatg ggtacaaaaa agacgagacc ttgggggagt aatctttatc gacctacgtg
    35761 atcgtgaagg aatcgttcaa atcgtcttta atcctgaaat caacaaagaa gcatgggaaa
    35821 tcgcggataa atgtcgcagt gaatacgtga tcgaagtgac tggggaagtt agaagacgcg
    35881 gagaaaatgc agtaaatcct aaaatggcca ctggtgaatt cgaagtgatt gcaagtgaaa
    35941 tcgtgatttt gaatcaagca aaaaccccgc catttcaaat tgaagatgat caagcaatca
    36001 gtgacgaaat acgtttgaaa tatcgttatt tggatctgcg tcgtccaaaa atgactaaaa
    36061 acatcaaatt aagaaatgcg acaacaaaag cgattcgtca ttatttagat gataatgact
    36121 ttctcgatat cgaaacacct tacctaggga aatctacacc agaaggcgca agagactacc
    36181 tagttccttc acgtgtccat gctggacatt tctatgcgtt gccgcaatct cctcaattgt
    36241 ttaaacaatt gctgatgaat gctggattcg accgttatta tcaaatcgtt cgttgtttcc
    36301 gcgatgaaga tttacgtgga gaccgtcagc ctgaatttac gcaagtagat attgaaacaa
    36361 cgttcttaac agcagaagaa atccaaactt acacagaggg attgattgcg aaggtaatga
    36421 aagaagttcg cggtatcgaa gtcacattgc catttcctcg tatgacctat gatgaagcaa
    36481 tggctcgcta cggcagcgac aaaccggata cacgttttga tatggaattg atcgatctaa
    36541 gcgatacagt caaagaagta gaattcaaag tcttccaaat ggctcttgaa aacggcggtg
    36601 tcgtgaaagc attgaatgct aaaggcgctg cagatcgcta ctcacgaaaa gacatggatc
    36661 agttaggtca atatgtagga caattcggag ctaaggggct tgcatggctg aaagtagaag
    36721 aagacggatt gaaaggtcca attgctaaat tcatgggaga agcaacagaa gcaatcatta
    36781 aagcaacaga tgcaaaacca ggtgacttgc tgatgtttgg cgcagataaa agtgaaatcg
    36841 tcgctgctgc attaggtgct atccggacac gtttaggaaa agaattagga ctaattgatg
    36901 aatcgaaatt caatttctta tgggtaactg attggccaca atttgaattt tcagaagaag
    36961 aaggtcgata tgtctctgct caccatccat tcacgatgcc aaaagaagaa gatatcccgt
    37021 tattggctga agaccctgca aaagtctatg cagaagctta tgatatcgtc ttgaacggtt
    37081 atgaactagg cggaggttct atccgtattc atactcgtga gcttcaagaa aaagtactag
    37141 aaactctagg ctttacaaaa gaacaaatgg aagaacaatt tggtttcttg ttaacagctt
    37201 tagattacgg attccctcca catggcggta ttgcattagg attggaccgt tttgcaatgt
    37261 tattagccgg agaagataat attcgtgaag tcattgcctt tcctaaaaac ggaaaagcag
    37321 cagatgtgat gagtgatgca ccaagtatgg tttcgccttt acaattgttc gaattgaata
    37381 ttgatgtaac gaatatagaa gaatagccga taaaaaggta aaaaggattt gtcgaatacg
    37441 cttcttttga caaccttgat ttaattgaaa aacactttat aatgaagcca taacatataa
    37501 agcggggctt ttccatgaaa aaaacattcg aaaattgggc ttatcatgat tacacgacca
    37561 agctttcggt atctatcgtt tatgcgttga tcgcatcagt cgcattgaat ttcttttatc
    37621 agccaggaca tatttattca agtggtatta ctggtctagc tcagattttg acgactttgt
    37681 caaaatcact gataggattc gaagtaccgg tatcaacaac tttgtattta ctgaatatac
    37741 ctttgtttgt attggcgtgg ttaaaaatcg ggaagaagtt tacaattttc acttttatca
    37801 cagtcacttt gacctccctt tgtatccata ttttaccgga aacagtccta tctaccgatc
    37861 caatcatctg tgcgttgttt gggggggctg tgatgggact aggtattggg ctagcgttga
    37921 gaaacggcct atcatcgggc ggtctagata tcgtgagtat cacgattcgt aaaaaaacag
    37981 gaaagtcgat tggttctatt tcgatctact tcaatgcatt gatcgttttt gttgccggaa
    38041 ttctatttgg ctggcaatat atgttttaca gtacgttgtc tattttcgtc agtggaaaag
    38101 taactgatgt cgtttatact aaacaaaaga agatgcaggt aatgatcgta acgaaacatc
    38161 cagaaaaagt agtaaatgaa atccaaaact gtatgcgtag agggatcacg atcatcaatg
    38221 aagcagaagg tgcttataag catgataagc agacagtatt gatgacgatc gttacacgat
    38281 acgaactgcc tctacttaga gaagcaatga aagcttctga tccacaagct tttgtaagta
    38341 ttgcagaaaa cgtccagata cttggtcgtt tctatgagga tggcatttag atcgagtttg
    38401 acaaaaattc atgaaatact gctgtagaca gacgttcgtt tgtctgcagt ttttttctac
    38461 catagtagaa tcagcaaaga aaaactgctt ttttatttga aattttctta aagttgaaaa
    38521 aaagcatgtt tattttttta aatttatggg atgatagaaa aaaatagtag agaaaggaca
    38581 cgattctact tgctattttc acttaatacc cgtatattac gaatgaaaaa agtttatgaa
    38641 aagttggaat attgaatgga aaaacaaaaa aggttaaaaa acagccgcta catcactggg
    38701 tttgatgggc tccgttcatt agctgtggtg ggtgttatct tctatcacct tctgccaact
    38761 agtatgaaag gcggctattt gggcgttccg atttttttcg tcgtatctgg ttatttgatc
    38821 acggatctgc tgcggcagga atgggaacaa aatggaaaaa tcaatatttg gcaattttat
    38881 gtcagaagaa tgaagagact ctatccggca cttgttttta tgcttgtgac agcttcggct
    38941 tatatcactt tgtttcagcg agggctgtta aacaatcttc gaggagttgt ggtcagcagc
    39001 ttactgtatg tcaacaactg gtggcaaatc aataacggtt tatcttattt cgatcgattt
    39061 gctaatgagt caccgtttac gcatatctgg tctttagcag tagaaggtca aaactatttg
    39121 gtttggccga tcttgtttgt attgttgatg gtatttgttc gtaaaagaaa atggatcttt
    39181 tatactgtgt taggtacatc cttcctctcc gccatcttga tgatgatctt gtatacacca
    39241 ggaggcgatc caacccgtgt ttattacggt accgacactc gtctgttttc tatatggttg
    39301 ggaagtgcgc ttgcgtttgt ttggccaagt acgcgtttaa agaaaaacat cccgaaacaa
    39361 gcgaaaaata ttctgaatat cgctggagga atctcgcttt tggcactgat tctttgcttc
    39421 ttctttttag atgatcatta caatttcatc tattacggag gaatgctcct agtgagtctg
    39481 ttatgcgtag tgctagttgc agtgacagca caccccggag caagtttgaa tcgatggctg
    39541 acaaatccag tatttacttg gattggcaaa cgaagctatg gcatttatct gtatcagttt
    39601 ccagttatga ttttttatga agcaaaggtg actgatattg ccgatcatgt tttgttgcat
    39661 actttagtgg aaatcacatt gattctaatc atcagtgaac tttcttatcg atatgtggag
    39721 cgtccgctag cacgttttga ttatggtcgt acattccaag tgatgaaagg atggttcagc
    39781 aaaccgatca tcagtaagag caaaccatgg gttgttccag gcacattact tgtagcaatt
    39841 gcactcgttg gtttcgttac ggcaccgaaa aacgctgtaa cagccgatca aaaacaactg
    39901 caggcaaaaa tcgctgaaag taaaaaatta gcagaagaaa ccagaaacaa ttcagaaaac
    39961 accactagtt cggttgacca agcgatcctt gataagtacg agttgtccaa ggcacaaggg
    40021 aataaggcac aaaaattaga actaacggca tttggtgatt cagttatgtt ggatgctgca
    40081 acggatctac aagaacttta tccaaaagta gtggtagatg gagatgtcgg acgacaatta
    40141 tatgccagtg taccgtacat tgaaaaatta aaggaacaag atttgttgaa agacactgtt
    40201 ctgatcggac taggaacgaa tggctcattc tcggaagctc agtttgatag tgtgatggat
    40261 gcaatcggtg atcgaaaagt atactgggtc aatgtccgag taccgacgaa gcgctggcaa
    40321 aatgacgtga atgcgatgct tgaacagatg acgaaaaaat acgacaatat gacgctgatt
    40381 gattggtaca gctacagtaa tgaccatagt gactggtttt atgatgatca agtccatcca
    40441 aatcctgaag ggatgacaca ttacattcac ttagtcagcg aagccttgct aggaggaagt
    40501 tcaagtacga acagcagtga gacaaacgtg acagaatgat agctacaaaa aacttcaggc
    40561 aaaaacattt gtttttgcct gaagtttttt tatatttacc gtgtttttaa cattcatata
    40621 gattcaggaa gcaaaacggt tgagtgtgtc tgtaaataac gttctttttg ttttcgggtg
    40681 agttttttga atgcagcttc tgcttttgtt gcttcgcttc ttgaagaaaa tacttctgca
    40741 tggatcatct taacaggtct tcttttttga agacgagtat atttagcacc agtaccattg
    40801 ttatgttcct ctaatcgtct agaaagatcg gttgtatatc caccataaaa tgtctgatct
    40861 ttacagaata atacgtaaaa ataatgttca tttgccatag agcatctcac gaatctctgc
    40921 agtgtattct ccatccatat tgtaagtgat caatggtgga gcgactttga atccgtctaa
    40981 tttgccttct ttgattcctt caactaacaa aatatttgcc tcttttccag gttttgggta
    41041 aacaaattgg atccttttag gtgcaattcg atagtcttcc atgacctgaa tgatttctaa
    41101 gaaccgatca ggacgatgga ccatagtaaa gcgtccattt gtttttagta gcttacttga
    41161 aatatcgatc acttcttcta acgtcgtatg aatctcatga cgggcgattg ccaggtgttt
    41221 attagggttc gttttatttg ttggcagccc tttgaaataa ggtggattac agacgactaa
    41281 gtcacaagaa ttatgtcgaa cgacagataa gctgtctttc agatcgatgg tgtggacagt
    41341 catttgttca tttaaatggt taagcgcgat actacgtctt gccatgtctg ctagacgagg
    41401 ttgaagttcg atagcgtcga tagccgcctg ggttcgttta cttaaaaaaa gtccaactgc
    41461 gccatttcct gcacaaaggt caacaatctt ccctttttta ggtacacggg aaaagtgagc
    41521 aagcagcaca gcatctaaag aaaaagaaaa cactttggaa ctttggataa tcttgatatc
    41581 ttctgcgtat aattggtcga ttcgttcgtc ttcgtgaagc atggattccc tccaaaatga
    41641 aaaaaatagt cgtctgtatt atactatttt tattaaaaag aaccaaggtg gcttgtcaaa
    41701 cctctatttt ttatgcatac tatgaccata agaagggaaa ggaagagact atgttttatc
    41761 gatttatgcg cggggtagtt cgagtactat tagccttagt taatggaaat gcccgctatg
    41821 agaataaaga agttttaccg caagatgaga attacatact agttgctccc catcgtactt
    41881 ggtgggaccc attatatctg gcggtagctg cagcacccaa ggaattcagc tttatggcaa
    41941 aagaagaact gttcaaaaat ccagttctgc gatttatatt aactcgatcc aatgcttttc
    42001 cagttaaaag agaaaatcca ggaccaagcg tcattaaaac acctgtaaag attttgaaat
    42061 cgacaaattt gagtttgatc atgtttccca gtgggacaag acatgctaca gaacttaaag
    42121 gcggaatggc attgatttcc agaatgtcta aagcgaaaat cgtgccagct gtatatcaag
    42181 gtccgttgac acttggggat ctgttcaagc gtcagagagt gacagtgcgt ttcggcgaac
    42241 caatcgactt atcagatatc aagaaaacgg ataaagaagg tatggcggag atcgaacgac
    42301 gaacacaagc agcttttgac aaattggaca aagaagtgaa ccctgatttc aaatatgaag
    42361 tcaaaaaaaa ataaaatgat aagtttatgc gtgggcggtc ttttgaatct actgtcctgt
    42421 tcagttcaga ctttttcaat gaaaacgagg gagagacgtc aagtctgccc tctttttgcg
    42481 ttccaatatg taaaatagaa gacaggtgtc atgtaatgga tcaaagtgtt ataataatta
    42541 gaaggacatt ttttgaggtg attgaatgcg ttttttacat acagccgatt ggcatatcgg
    42601 aaaaaaacta caaggttatg acttgattga agaccagcgt catgtactat cttctatact
    42661 agatatcgcg aaagaagaaa aagtagaggc aatcgtgatt gccggagact tatatgatag
    42721 gagtgtccca gctgttgatg ccgtagaatt atacaatgaa ttgatggtcg attggaattt
    42781 aaaggaaaag atcccgattt ttgctatatc aggaaatcac gatagcagta cgagactttc
    42841 agcgggtacg ccatggttca gttattcgaa ctattttttg cgaacacagc tagcagaagc
    42901 atttgaacca gtcgagttta aaaacgtaca atttttcttt cttccttact ttgaaccaat
    42961 tgcagcgaga ttatattttg aagatgacaa tatccgaacg atcaagcaag cggtagccaa
    43021 ggtgatagat aaaatgcagg agctatttga ttcagaaaaa aaacaagtat tgattagcca
    43081 tttttttgta atgggaagtg taaaatctga ttcggaaacg aaaatcgaag taggcgggtt
    43141 ggattcgatc cctggtgaac tacttacacc gtttgattat gtagcactag gacatttgca
    43201 taatcaagct gctttgagac aggataatgc tcgctatagc ggttccccat tgaaattctc
    43261 tttatctgag atcaaccaaa aaaaaggcgt atggatcgtt gacctgacaa caggcctgga
    43321 gttgaatttt agggagatcg aacccctgca tgatattgaa gaaataacag cgagtttcaa
    43381 agaattgctg gatcctgcct tttatcagtc cgtcaatcgg gagaattaca tctatatcta
    43441 tctcactgat agaacgatca tcccgaatat gatgaaccag cttcggcaaa tatatcctcg
    43501 tattttgggg attgaacggg caaacggtcg agcagaacaa acaaagcgca aacgaaaagt
    43561 actagaaatg aaagatcctc aaaaattagc agaagcattt tttagtgaaa tgacggaaga
    43621 gcagctaact gcaaaccaag aaaaatggct cggagaaacg ttgcaagaaa tcatggaaat
    43681 ggaatgatca agaatgaaac cgaaaaaatt acaacttaaa aattttggtc cttttatcaa
    43741 tgagaccgta gatttttcac gtttgacaga agcaccgctt tttttgatca gcgggaagac
    43801 aggagctggc aaaacgacga tttttgatgg gatcaccttc gcactttttg gtgaaacttc
    43861 cggaagactt cgctctggaa aagagatgcg ttctttgttt gctacaccag acgaagaaac
    43921 aagcgtgact ttttcttttg aacatcagca gatgagctat gaaatcgaac gaaaaccaga
    43981 acaagtttta gcaaaacgaa aaggaaacgg aacaaaaaaa caggcagcca aagtaacgtt
    44041 gaccattttt gatgggaaag gaaaagaaat aaaacaaatc acaaaacgta cagaagcaga
    44101 tcagttgatc agagaactga tgaatctcga tgcgaaacag ttttctcaaa tcgttttact
    44161 accccaagga gaattccgta attttttggt ttcatcaagc agtgataaag agactgtttt
    44221 acgtcattta ttcggtactc aatttttcca acagttcaat gagcgattaa aagaaaaagc
    44281 aaaacaacag caacaaaaat tggatcattt agagcaagag ctgcatcttc tgcaaaaaag
    44341 gtttgtttta gtcaaagaag aggaaccagc agcagggttt gaagccgttt tagcccaatg
    44401 gacaaaccat caggcaatac tcgaaaaaca aatcacggaa gaaaaagaag ctctaacgga
    44461 acttcaggaa aaacaaaagc aactagaaaa ttcctactat cgttttgaaa gcttgaaaaa
    44521 aagttatgaa gaaaaaacga tattaataaa caagcaaaag gaattagctg ctcaaaaaga
    44581 cgaaatagag gaaaagaaac gatggattgg gtattatgaa tttacgcaac gattagtcga
    44641 accaatccag cgcctacaag aaataaaagt tgaaaaaata gaactgtcac aaaaaagtag
    44701 tgagcaaaca aagaaactag cgatgactac gcagaattat gaagagtggc aaaaaaatga
    44761 agcaaaccgc gtacgccgac aaacaaaaat caaagaagct gctcaaaaac tgcaaaacaa
    44821 acagatgatg gtgccaattg tcgaatcctt acgtagtaaa aaacaagacg cagaacaatt
    44881 aacaatttca ttggataaag aagaattgaa tgccgagaag ctgtatcaaa atctcgctat
    44941 ctatcaggaa agaactcgaa ttcttcaaga aaatttactg gatcaggaaa aactgcaaga
    45001 agatcgtctt gcttttggac agttaaaata tctagatgaa aagcagcaag aaatagaaaa
    45061 acaaaaagca aaagacactg ggtcgctcgc acagataaga gaagaactca aaaaagcaac
    45121 tgaagaaata acaaaaaata gtcagctatt gaaagaacag acagaacaag cagaacagct
    45181 gaaaagccaa tgggcaaagc agcaaattgc tcgtcttcag ctttttttgc gtccagggga
    45241 gccatgtctt gtttgtggat caacggaaca ccccatacaa caattaaaac acgaacagcc
    45301 aaataaggaa gatatcttaa aagtagaaca acaactggca gaagctgagt ctgctgtaga
    45361 aagaactcag caaatcattg ccaaaagtga agcacatgaa aataatcttc aacaacaatt
    45421 atcagattta gaacaaaaaa tcatggcaac gaatatacaa ttggctgaac aagaagaaca
    45481 cttgcaacag gctttgaaaa aggcatttcc tgagataaca gaacaaaaaa caaaaacaac
    45541 tcttgtagta atcgaacaat ctttagatag acgaaaaagc aagatggcca atgcaagaat
    45601 agagctggaa gaaataagac aacaagcaga aaagctcgaa caacaattag ctgtctacaa
    45661 acagcagcag acagaaaaaa ataatcagct ccagcaactg caaggagaaa tcaaaagttt
    45721 agaacaacaa ttgcaagata cggatagtaa ctgtttagaa gaggagatac gacgacttga
    45781 aaaacagtta gaagaagact cgaatcaact agctgttgag cagaaagcag gagtgcaatt
    45841 gttgcaagat cttcatacgc ttcggacaca gcttgatctt caacatgaac aaatagaaaa
    45901 aatagatgaa aaaatagaaa aggaacaaga aagaatagct aaaaagttag aaagccagtc
    45961 gtatttttca acaattgaag aaatctgtgc atttgcacaa cagcaagcac aatataaaga
    46021 aaaccaacgt acagttactt cttatcatga agagcaatta gtgacagctg accggctgcg
    46081 tcaattagaa aatatccagc taactgagac attcccagat acagaagaga tcagccaaca
    46141 gttagaagaa ataagacgta tgatcgaaat aaagcaagaa aagatatacg gtttacaaga
    46201 acaaaaaatt agtaatcaaa aaatctacga tgaatgtctt tcgatttatc acacaagcca
    46261 gacgaaatta gatgagctta cgcaattaca gcagctttcg caaacattca acggagaaaa
    46321 tcctaagaag actagtttgg aacggtatgt gcttcaggtt tatcttcaag aagtgttaca
    46381 agtagcaaat gatcatctcc aacgtttaac gaaaaatcgt tatcaatttg agctagcgga
    46441 taccattggc agttatcgag ggaaaaccgg attagaaatc aatatctatg atgatcaggc
    46501 aggtatgtct cgaagtgcgc ataccctgtc tggcggtgag agttttattg cagcactttc
    46561 tttagcatta gctcttgccg atgtgatcca gacacaagct ggtggtgtag caatcgatgc
    46621 attgtttatt gatgaaggat ttgggtcatt agatgaagaa gctttggaaa tggcaatgga
    46681 agctttagaa acgatcgaaa gtgaaggaag aatgatcggc atcattagtc atgtaagaga
    46741 attgaaagaa cgagtattac aacaaataag aattgataca gaaggtagcg gacaaagcaa
    46801 aatacgctat caacttggat aaaaagggag attggtaact atgaaatgga gtattccaga
    46861 aaaagtcatt gcacgtggac gtcaatactt gcaagaaggc cgagtgttat cggttgtccc
    46921 tgaccaagaa gaaaacgtgt ggcatgcaga agtcttgggc agtgaattgt atatggttga
    46981 tttggatggt acagcaaaag agatagatta ctgccaatgt ccctattggg aggaacataa
    47041 atattgtaag catacagttg ctgtggaact ttatttacgg tcgaaaaatc tatctcgtat
    47101 catgaaaaaa gaccagccaa tgctagaacc ggtaaaagca acaagtgagg gagaaatcat
    47161 tgcaaaaggt ttttctcgtc taaaaacaca aaacaatcct caagcggtgc aacctttgat
    47221 tattgaatac caagtagaaa cgattgagac taatcagtat cacccagagc tttctatttt
    47281 ggcactttac ttgcgtatcg gttcattggc atcaccgaaa aaaacatata tcgtaaaaaa
    47341 catctatgat tttttacaag cttacacaga aaaagaaact tacactgtta ataaacagta
    47401 ccagtttcgt ctagataaac gggcgtttca aaaagaagat caaaaaatac tcacgcatct
    47461 tgcaggaagt gctcagacgc atcaattatt aggtacgaac ggcttacaag tcaaaggaaa
    47521 actagataaa agatatctgc ttctcccagt agaacaagcc cgcttcctgt tagagcagat
    47581 gaatcagact acacgtttgc atctgcagat aaatgaacaa aacgatcaag gaatacaatt
    47641 ttccgatcaa aacaaacctt tatcattcaa agtggaaaaa tttggagaag attatttgct
    47701 gcaagcattg aatgattttg attttttctt tatgcattat cagtggggag ttatccaagg
    47761 gacattttat tctctgacga aatatcaaca aacggtttat caaacttgga aacaattgat
    47821 tcgccgattg gagaaaccag aagtagtgtt caagaaaaaa gaattaccgt ctttgtttaa
    47881 agagattatc cctctgctgt cagagatcgg cgacgtagct attgcccctg cagtagaaga
    47941 ggaagtagca gatatccccg tcgaatttat tttctttttc cgaaaagcaa aaggaaaaat
    48001 ccaagctcga gtcgatttcg tctatggcga agtcatctat tcgactgacc cgaagcatga
    48061 ggtctcgaca gaacaggctt ttcaggtgtt acgtgacaca gtagaagaga aacgagtact
    48121 tgatctattc agaatgtatc gctaccagaa aaatgaaact ggttatgaac gtccattgcc
    48181 aagcggggaa gaactatatg cctttttccg cacagaacta tctgtcttcc gtcagtttgg
    48241 tgaagtcaga cttggaagaa aattgcgaga gttgtattta gatgcgcata aacatcaacc
    48301 gaaaatcgaa gtaaccgaga ccggttcatg gctcgatatt cgattcgatg tgacagggat
    48361 agaggagcaa gaaatcgatc atgtcctgca aagcttgctg agaaatgatg ctttttatac
    48421 attagaaaat ggtcaggttc tttcttttga ttcagaagaa tttcaacaaa caagccaagt
    48481 gttgcaacaa ttacgggaat cgatacgtac agaagaagga acgatccatg tacctaaaaa
    48541 tcaaggattg atcattcaaa atcaattgga aaaaagcaat gctactttta gtgaatcgtt
    48601 ccaaacgatg gtacaagatc tcattcatcc agaaagatac caggcacagc ttcccaaagg
    48661 attgaatgca acgatgagag attatcaaaa gcaaggtttt cgatggttga agatgttagg
    48721 tcattatcag tttggcggta ttttagccga tgaaatggga cttgggaaaa cactacagac
    48781 aattgccttt ttactttcgg aaaaagaaga acggaaaagc ttctctgctt tgatcgtagc
    48841 gcctgcgagc ttaatttaca actggcaggc agaggtgaga aaattcgccc cttctttaag
    48901 tatccaagta atcaatggga ataaaaaaga acgtgaagaa ttactggcta aagacacaga
    48961 tatccgagtg acttcttatg ccagcttaag acaggatcta gctaattatc agtcgcaaaa
    49021 aattgattat ttgattcttg atgaggcaca aatggtcaaa aatagcagta cgaaaactgc
    49081 acaagcattg agagaattag ctgtacctca gcggtttgca ctgagtggga caccaatcga
    49141 gaataattta gaagaattgt ggtcattgtt tgcaacgatt atgccaggat ttttcccgac
    49201 taaaacaaaa ttcagggaac ttgccgcaga agaaattgcg caaatgattc gaccgtttat
    49261 tttacggcga gataaacaaa ctgtgttgaa agacttgccg gaaaaaacag agatgaatct
    49321 atattctgca cttacagaag aacaaaaaac tgtttattta gcttacttgc gtcaaatgcg
    49381 tgaagaaatc acatcaatgg attctgaagc attcaagaaa aaccggatcg ggatacttgc
    49441 tggtctgaca agactgcgac aaatttgctg cgatcctcgt ctgtttattg aagattacca
    49501 aggcggttcc ggcaagctcg aacaagtaaa agatctactg gtagctgcca aagagaacaa
    49561 acgaagagtt ttgctgtttt ctcaatttac agggatgctg actatcttgc aagaagagtt
    49621 agccgagcta gggatctcga cattttattt aagaggcagt acgaaaccac aagatcggtt
    49681 aagtatggta gacgcattta atgctggcga aaaagatgtt tttctgattt ccttaaaggc
    49741 tgggggaact ggattgaatc tcacgggagc agatacggtc atcttgtatg acctttggtg
    49801 gaatcctgcc attgaagaac aagctgctgg acgtgcacat cggatcggac aaaaaaatgt
    49861 ggtagaagtg tggcgtatga tctctgaagg aacgattgag gaacgcatgg attcactcca
    49921 gcaagaaaaa cgcgaactgt tccaaaaagt gatccaaggt aatgaagaac agttgacgaa
    49981 actgactgaa gaagacatcc gcatgatttt aagtgtagga gaaatcgagg agtaagagac
    50041 tcgaaaaagc gttcagtaat gggtaagaaa gcctttctaa agaagcgatt gtttatttga
    50101 tttaaaaaat agcaaggagg ctgggattcc attttatccc agcttccttg ctatcatttt
    50161 tttatttcta tttttaaagg ttatacaaag attgtcttca ttgtctctaa cagctgatca
    50221 aaagaagaaa tctcgatatc gcaaattgga gtctgttcaa ttttgcgttc tcgatggttg
    50281 aaccaaagcg cttgccagtt agcacttttt gcacctagaa catcattgtc gtaattatcg
    50341 ccaacgtata aggtctcttc tggaagcata tgaaattctt tctcagctag ctgaaaaatc
    50401 tctttttctg gtttttggaa acctgttgct tgagaaatga gcatattgcg ggaaggaatc
    50461 caattgttca attgaagttg cttcagtttt tttgtctgat ggtcagtcgg cccatttgtg
    50521 ataattccta atgggacatt cttttccttc aagaaatcga gggttttttt gacctcctca
    50581 tgcaagcaga tattatcaag ttcttcctcg taaatttttt gaaataagag gccatcttct
    50641 tccgtaatat gagggtagtc taaatctttt agtgattggc tgatccgatg tgctcgcata
    50701 tattctagtg tccaatctcc tgccattact tttgggaagt tttcatcact atgatggcgg
    50761 aaccggatat atagtggatg catatctgca tctgaaacaa gcggaacgac tcttttgacc
    50821 gcgtttcgaa atggctgctg ctgatcatac atcgtatcat caacatcaaa cacaactgat
    50881 ttaatcaaaa ttttacacgc ctttcggttt tcattgattt tttcacaaat ccttgactat
    50941 tgtaacagaa aaaattgtct aaaaaagctg ataaataaag gtttttctta ctatatttct
    51001 atttccttga cagaataagg tttttatatt tcagtttttt tcactaaaaa tcgtgaaaca
    51061 cgtcaataag tttgatgaac aaattaatca ttatggtaga agtcgattga tttattttaa
    51121 tgcaatctct gtggaatttt cgaaagattt atttttttaa tacagtctca atataactat
    51181 tcaaacataa aataacgtta tttgatttat ttgtttatag taaattttat ttagtaatca
    51241 ttgctttaaa atactacgct tatataacag agaaaataag cgttataata aagaacagta
    51301 ttatttaaaa tgacagaaaa cattactatt aaagaaataa aaaacataaa aaatcttaag
    51361 aaatcggttt catttagctt ttgagataaa ataatagtac agttttatac gctgtttcat
    51421 atgtttagaa aatttgaatt agatttgaaa actctaattt ttaaatgata aaaaaagcga
    51481 gaatgctggt tttactgtat attaacctta gataactttc atttttttaa aaaaattatg
    51541 aaaaaaaggt agctatttaa aagttgatta tgtataatag aaacagatgg gagattatta
    51601 tgatcttctg ttacaaaaaa gtgattctta tcacgaaaag gagtggtgca cgttgttaac
    51661 attatatact tccccaagtt gtacttcctg cagaaaggct cgtgcgtggt tgcaagaaca
    51721 tcagattcca tttgttgaac gtaatatttt ttcagaacca ttgaacagtt ctgaattaaa
    51781 agcgatttta caaatgacag aagacggaac agaagaaatc atctcgacac gttccaaagt
    51841 attccaaaaa ctgaacatgg atttagatga tctgccgtta caagaattat tggaacttgt
    51901 gcaaaacaat cctggattgc ttcgccgtcc aatcatgatt gatgataaac gtctgcaagt
    51961 tggttttaat gaagatgaaa ttcgtcggtt cctaccgcgc gatgtacgac aattagaatt
    52021 acgtcaagca caattgatgg ctggattata gaaggataat acgaaacttg gaaaagacta
    52081 ttacaaagat agtttttcca agtttttttg tttttacaaa aagtattctt gattagatgt
    52141 ataaaaaggt agtagaagat gatgattgca cgaaaaatag agagggaaaa ttagctgaaa
    52201 agtcggctat atagtattcg tctgccaaaa atgttatagt taaataagat agcttgaaag
    52261 gttgaaaaat ccgctggttt tattaaattc gcttaacagc gagatttttt ttctttacat
    52321 ttaagctgat ttcgctacaa tgaatctata ttaaacattg tggcaaagtg aggtgtagca
    52381 aaatggaaat ggaacatatt aatgaaaata cgatccgtgt actaattggt catgaagatt
    52441 tagaggaacg gggcgtttca tttttggatt tacttggcaa tcacaaagaa atcgaaaatt
    52501 tcttttatag tattttggaa gaagttgata tcgaagagga gttccgagga agcgaagctg
    52561 tcactttcca agttttgcca aaaggagacg gattagaact gtttatcagt aaaaatcttc
    52621 cggatgaaga aatttctcaa tcagaagatt ctactgttga ttcagaagat gtgagtgact
    52681 ttcttcgtca gcagattatt ggcagcgatc cggaggaaga attatctgga agcgccctag
    52741 aagaacagga aagacaagca acttttgctt ttgaagattt tgaacaagtg atccaacttg
    52801 caacagatgt cgaactagag tctgcttgga ctgatttgta tttattcgaa gagcgctatt
    52861 acctagtcgt tcacttctgg atggaaaatc tcaaccaagc ggatgtagag aatcagattg
    52921 ctcgaatttt ggagtttgct gaaaagagcg atcgtacacc agaaacattg aatgaatatg
    52981 gacaatgtct gatggcgcgt aatgctatcg agcgaacgaa attttatttt gtataaatca
    53041 gcattatagt aagagactgt gacaaaaatt gtgtcgcagt ctttttttcg tataaatgtg
    53101 ttcaaaagct tgcatctgcg gtaacaagcc caaccaaacg aaaaatattg ggaactattt
    53161 ttgtttagct gttcttatta cttgatgcag aatagctttt tcacgccctc ttttttcgtg
    53221 taaataaatt cttagacgta aataagttca gagggagaaa aatgctgctt gcaatgaatg
    53281 aatataataa gtgctgtttt gctaaacatg cagaaaaagg aaagaaatat tattgtcgtg
    53341 gctgtcgaaa aagagtgatt ttgaaaaagg gaaagaaaaa atgtgctcat tttgcccatc
    53401 aaaaatcaga taactgttcg gtctttagtg aaagagaatc aaaagagcac ttacagttaa
    53461 aggaatgctt catggattgg ctgggacagt cagtagaacc agtatttttg gaagcctatt
    53521 tgccgaggtt gcggcaaagg ccggatattt tgttggcgaa tctagcaata gaaatccaat
    53581 gttctagact gtctcaccag agatttattg aaagaaccca aaattatttg aataacagtt
    53641 accaagtatg gtggatactt ggtaattctt ttcttggaca atcgcaattc tcattgatag
    53701 aaaaaagttg ctgctactat aatagaaaaa gaggagtgca ttgctggaaa gctgatctca
    53761 agaaacaaaa gctttatttg tatcatcata ttacagagac tgtatcaggg catatttcct
    53821 tttgcagtag ctgctggact ttttctagta gggaccttaa agaaatattc actagtaacg
    53881 aaattaaaat gaaccaaatg aaaaaaatag aaaaagtgag tgaagatggg aagaaatggc
    53941 tgacacgcca acttattcac aagcaaaaga atacagtatc catacaagaa caatgctact
    54001 tgcgtcataa acatcttttg catctatcat cgtggatcta tcaaaaaagt cggtttttct
    54061 tttatttaca agaacaggtt tttctttatc gaatgttgta cgaagaagcc ttggaaaacc
    54121 agaaagttcc tgatttcaac tcatggcttt gccaaataaa agaacataaa agggaatggc
    54181 tttttcctat gattgatgaa gagatggtct atcagcagtt ttttaacgaa tgcatacact
    54241 tgtcttcttt gaaaaaatag taagtataaa aataggctag gaatcggttt tctatgtaaa
    54301 acaagattta gttatgctaa aattgatgga agcagacaca tgaatgagta gaaaagttag
    54361 atgctgtgac atgtggatgt tagactatga tctattttga tagatagagc taagggaaga
    54421 aaaggagtgg atttcatgga agtaaagcag ttgccaaaac gagaagaatt gcctgaaaat
    54481 ttaacttggg acttgaccaa gatcttttca agcgaccaag agtttgatga gaaatatttg
    54541 gaattatcag aagagttaaa acaatctgaa aaacacaaag gaacacttga tcaaggcgct
    54601 tctcaatttt taaatgcgat tgaattcgta ttgagggttt atcgccaaac tgaagtcatt
    54661 tatgtatatg cgcaccttaa aaacgatcaa gacactggaa atacagatta ccaagcgctt
    54721 tatgcaagag caagcagtct gttttcgaaa gttagtgaag ccgtttcctg gtttgaacca
    54781 gaaatattgc aattgtcaga tgaccagatt tggcaatatt tcaaagaaga accaaaattg
    54841 gaagtctatc gccattatat ccagcaaata gtagataatc gagcccatgt cttatctgct
    54901 gagcaggaat ctcttcttgc tggagcaggt gaaatctttg atgcttcaag tgatacattt
    54961 gctgttttga ataatgcaga tctagttttt ccaacgattg aaggagaaaa tggtgaaata
    55021 gtccaattat ctcatggcgt gtatggtcag ttgctagaaa gcacggatcg aagggtgcgc
    55081 gaagcagcat ttaaggggtt gtacagtgtt tacgaacaat ttagaaatac atttgcttct
    55141 actttaggca cacatataaa aggacataat tttaaagcga aagtccgtaa ttacagctct
    55201 gccagagaag cgtctttgag caataatcat attcctgaaa gtgtatacga tactttggta
    55261 gacgtggtaa acaagcattt gcctttgtta catcgataca tggaattacg gaaacgttta
    55321 ttagaagtgg aaaaactgca catgtatgat ctttatacac cggtcttagg ggaagctcca
    55381 attaccttta cgtacgaaga agcaaaagaa aaagctttag aagcactgaa accaatgggt
    55441 gaagaataca tggccatcgt agaaaaagca ttctctgaac gttggatcga tgttgtcgaa
    55501 aataaaggga aacgaagcgg tgcttattct tcgggaagct atgacacaaa tccatatatt
    55561 ttattgaatt ggcatgatac gctggatcag ctatttacgc ttgtccacga aatgggacat
    55621 agtgttcata gttatttcac tcgttcgaac cagccttatg tgtacggcga ctactccatc
    55681 tttttagcag aaattgcttc gacaacgaat gaaaatatcc taacggagta tttattggaa
    55741 acagaaaaag accctcgtgt acgggcttat gtactcaacc attacttgga tgggtttaaa
    55801 ggaacagttt tccgccagac acaattcgct gaattcgagc atttcatgca tacggaagat
    55861 gaaaaaggtg tgccattgac tagtgaatac ctaagtgata gttatggtaa attgaatgca
    55921 aaatattatg gtccagcagt cgaagaagac ccagaaatta aattcgaatg gtcacggata
    55981 ccgcattttt attataatta ctatgttttc caatactcga ctggcttttc tgctgcttca
    56041 gcactggcga agaaaatact aaaccaggaa ccagaggcac tagagaacta cttggcttac
    56101 ctaaaagcag gtaacagcga ttatcctgtg gaagtaatga aaaaagcagg agttgatatg
    56161 acacaggctg catatattga agatgcaatg tcgatgtttg aacaacgtct aaatgaatta
    56221 gaagaattga tcgatcgttt ataaggcttt ctatttttga ttttctcgaa tagaaacgaa
    56281 aaaaatacgt cggctctctt gtaagggagt cgacgt
//
LOCUS       DAYNVV010000012        50351 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.012, whole genome shotgun sequence.
ACCESSION   DAYNVV010000012 DAYNVV010000000
VERSION     DAYNVV010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 50351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50351
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.012"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(59..187)
                     /locus_tag="ACGXWR_000871"
     CDS             complement(59..187)
                     /locus_tag="ACGXWR_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFK0802474.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="ACGXWR_000872"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="ACGXWR_000872"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFK0802475.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="ACGXWR_000873"
     CDS             complement(1674..2729)
                     /locus_tag="ACGXWR_000873"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFK0802476.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="ACGXWR_000874"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="ACGXWR_000874"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HFK0802477.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="ACGXWR_000875"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="ACGXWR_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HFK0802478.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="ACGXWR_000876"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="ACGXWR_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HFK0802479.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="ACGXWR_000877"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="ACGXWR_000877"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HFK0802480.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="ACGXWR_000878"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="ACGXWR_000878"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HFK0802481.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="ACGXWR_000879"
     CDS             10491..12050
                     /locus_tag="ACGXWR_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HFK0802482.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="ACGXWR_000880"
     CDS             complement(12161..14092)
                     /locus_tag="ACGXWR_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFK0802483.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="ACGXWR_000881"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="ACGXWR_000881"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFK0802484.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="ACGXWR_000882"
     CDS             complement(15021..15773)
                     /locus_tag="ACGXWR_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFK0802485.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="ACGXWR_000883"
     CDS             complement(15932..16141)
                     /locus_tag="ACGXWR_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802486.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="ACGXWR_000884"
     CDS             complement(16152..17480)
                     /locus_tag="ACGXWR_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802487.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            17616..17771
                     /locus_tag="ACGXWR_000885"
     CDS             17616..17771
                     /locus_tag="ACGXWR_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HFK0802488.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(17845..18432)
                     /gene="yihA"
                     /locus_tag="ACGXWR_000886"
     CDS             complement(17845..18432)
                     /gene="yihA"
                     /locus_tag="ACGXWR_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HFK0802489.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="ACGXWR_000887"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="ACGXWR_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HFK0802490.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /gene="tig"
                     /locus_tag="ACGXWR_000888"
     CDS             complement(20012..21301)
                     /gene="tig"
                     /locus_tag="ACGXWR_000888"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HFK0802491.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="ACGXWR_000889"
     CDS             complement(21455..22387)
                     /locus_tag="ACGXWR_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802492.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="ACGXWR_000890"
     CDS             complement(22544..23203)
                     /locus_tag="ACGXWR_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFK0802493.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="ACGXWR_000891"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="ACGXWR_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFK0802494.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="ACGXWR_000892"
     CDS             complement(24244..24534)
                     /locus_tag="ACGXWR_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802495.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="ACGXWR_000893"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="ACGXWR_000893"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HFK0802496.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /gene="glmM"
                     /locus_tag="ACGXWR_000894"
     CDS             complement(26821..28176)
                     /gene="glmM"
                     /locus_tag="ACGXWR_000894"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HFK0802497.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="ACGXWR_000895"
     CDS             complement(28200..29369)
                     /locus_tag="ACGXWR_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HFK0802498.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /gene="cdaA"
                     /locus_tag="ACGXWR_000896"
     CDS             complement(29366..30253)
                     /gene="cdaA"
                     /locus_tag="ACGXWR_000896"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HFK0802499.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="ACGXWR_000897"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="ACGXWR_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HFK0802500.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="ACGXWR_000898"
     CDS             34320..34841
                     /locus_tag="ACGXWR_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HFK0802501.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="ACGXWR_000899"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="ACGXWR_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="ACGXWR_000900"
     CDS             complement(36284..36940)
                     /locus_tag="ACGXWR_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802502.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="ACGXWR_000901"
     CDS             complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="ACGXWR_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HFK0802503.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38477..39475)
                     /gene="yvcK"
                     /locus_tag="ACGXWR_000902"
     CDS             complement(38477..39475)
                     /gene="yvcK"
                     /locus_tag="ACGXWR_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HFK0802504.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="ACGXWR_000903"
     CDS             complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="ACGXWR_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HFK0802505.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40491..41222)
                     /locus_tag="ACGXWR_000904"
     CDS             complement(40491..41222)
                     /locus_tag="ACGXWR_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HFK0802506.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41226..42491)
                     /locus_tag="ACGXWR_000905"
     CDS             complement(41226..42491)
                     /locus_tag="ACGXWR_000905"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HFK0802507.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="ACGXWR_000906"
     CDS             complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="ACGXWR_000906"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFK0802508.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="ACGXWR_000907"
     CDS             complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="ACGXWR_000907"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HFK0802509.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47833..49335
                     /locus_tag="ACGXWR_000908"
     CDS             47833..49335
                     /locus_tag="ACGXWR_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HFK0802510.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49337..50074
                     /locus_tag="ACGXWR_000909"
     CDS             49337..50074
                     /locus_tag="ACGXWR_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFK0802511.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
BASE COUNT        13905 a        10928 c         8860 g        16658 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagac cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagccat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
    37021 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
    37081 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
    37141 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
    37201 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cagttataga
    37261 taaatacttg atcttatcta tatcaggact tctatattaa gcaaaaattt atgtacaaaa
    37321 ctaaaatctt cattcagttg tctccccgct ttttatacga ttgtattaaa aacaatagaa
    37381 gcctttccaa attatgttac tccagtaaag atggaattat agtttgacgg aagaaaagca
    37441 agtataactt ttaaaaaaaa ctgatacatt cgcatctcct gcttcatgta tcagtttttt
    37501 ctttggatta aactgcttct tcacgcagtt tttccgcaaa ttcatttatt ttgcgaattc
    37561 ggtgattaat tcccgatttt gatatcgcac ctgagggaat catttcccct aattctttca
    37621 agctgacctc tggatgttga agccgaagtt ctgcgatttc ctgaagtttt tcaggaaggg
    37681 catgtagacc gacctttgct tcgatcaatt cgatgttttc gatttgttta gaagccgcat
    37741 caatcgtctt gttcagattt gctgtctcac aattgactag acgattgacc gaatttctca
    37801 tatcccgtac gattcgaaca tcttcaaatc ggagcattga gttggttgca ccaatcaatg
    37861 ttaagaaatc agcaattttt tctgctcctt ttaaataaga aatatagcca ttgcgccgtt
    37921 caagcgttcg agcatgtaga ccgtaataat ttaacatatc gcaaatgtct tggttatgct
    37981 gttcataaat agaaaatatt tccaaatgat aacggctcgt ttccggatta ttgactgaac
    38041 ctgaggccat aaaagcacca cgtaagtaag aacgcatttt ttgcgaattt cccataatct
    38101 cgtccgaaac gtgtccattg aacatcatac catccatgat atcaagatcc atcaacacat
    38161 cttttgtgcc ttgcttcaac cggacgatat agacattgtt cttttttaat ttcatttttt
    38221 tacgaacgag tagctcactt cgtacctgat aatgatcttt caaaagagaa tagatacgtc
    38281 tggcaattgc agcattttct gtttggacgt tcaaaataaa ctgctggttc acaataccta
    38341 aagagccgtt cattcgcagc aaagcagcta attccgcttt cgcatgttct cgatgaactt
    38401 ccaaaccagt tagttctttc ttcacatctg cagcaaatga catcctattc tcctcctttc
    38461 tccaacaata aattgcttaa tattttgaac cgaaaactaa acggaacaat tcttctacta
    38521 ctttgtctcc atcgtggaag acaccaccat ctttcaattc caaaaagtcg gtggaaatca
    38581 ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc gacttgtact agatactcat
    38641 catagatctc tgggtccata taatcttcag gcactttttc cgtattgacc aatactgtat
    38701 cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat atgatcggca tctgtgaaat
    38761 gttccgtttc ccctttttgg gtcatgatat tacagatata gacggtttca gcagttgtct
    38821 tgagcattgc ttcgccgatt tctggtatca ctaaatttgg aaggatactg gtgaataaac
    38881 ttccgggtcc caaaacgacc atgtcggcgt ccataattgc tgaaacgact tttcgagccg
    38941 ctttggcttc acttttatca tttgtgttgc agacatacac acggtcaatg gttttacggt
    39001 cgatcgcgat tttagattct cctactgcag tcgttccgtc tttaaagaca gcatgcaagg
    39061 tcaaaggagt ttctgaagaa ggataaacat gtccatctac atgcatcatt tttgctaata
    39121 attgaatcgc ctcataagtg cttccccgca tctcggaaac tgcggcaatg atcagattac
    39181 cgatcgtatg attggctaaa aactgatctt cctttttgaa acggtattgg aaaatatctt
    39241 catagaattg tggcatatcc gataacgcca ctaagacatt tctcaagtca ccaggaggag
    39301 ccatagcgat cgattctctg attgcaccgc tgcttccccc atcatctgca acagtcacta
    39361 ctgctgtgat atctgctcct tgatttcgca aacttttcag gataactggc agaccagtgc
    39421 caccgccgac cactacgatc tttggttttc ttatccggta ggttttcatt ttcacgaccg
    39481 gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc acattgactt tatagttttt
    39541 ccctaaagca tttgccaaac gttcagtcaa tgccacagaa cggtgttgac cgcctgtaca
    39601 gccgattgca actgtcaagc tgctttttcc ttctttaatg tatccaggca atacagtttc
    39661 cagaagatcc aaaaatttat ggtagaatga ttgcgtttca tcaaaggaca tcacataatc
    39721 atagactggc tgatcttttc cggtcaatgg tcttagttcc gggatataat gagggttggg
    39781 caaaaaacgc acatccatca caatatccga atcgatcggc aacccgtatt taaaaccaaa
    39841 tgatacaaat tcgatccgaa atccttggtc tccctttgat ttgaatgact cattgatttt
    39901 ttcacgtaat tgtcgtggtg tcaatgtcgt cgtatcaatg atcacggaag cttgggcttt
    39961 caagtcgtct agtatcgccc gttctttacg tatcccttca gtgatcaaac cgtccatcgc
    40021 cattggatgt gctcgtcttg tttctttgta gcgagccact agttcttcgt ctgaagcatc
    40081 taaaaataag atagaagtgt cgatgaagtt cgtattttcg atttcgatca gcatgttttg
    40141 gatttcttca aagaaggaac gagaacgtaa atccactcct aaagccattt ttgtgacttt
    40201 gcctgattct ttgattaatt cccagaattt tggaatcaat cgaggcggca tattatcgat
    40261 acaaaaatag cccatatctt caaaactttg gatagctact gttttccctg caccgctcat
    40321 acctgttatg atgactaatt gcaaattatc tgtcataatt acgaactcct ctcacattgt
    40381 gcatagtaaa attatatcat tccgggcgta tcattaccag ttttcttttt cttttacaaa
    40441 aagatttgga ccaaatatct tttaggatat ttgccccaaa tccaattttt ttacttttcc
    40501 gatgctgtat ccaatgcctt gcttctttca gctagcgctc gttcaatcgt ccgatctgct
    40561 aaaatagatt gggcatcgat cactggataa tggttatctt cagcaaattc atgcatcaat
    40621 gacaattctg tgcaacctaa gataactttt tcacagttta ggcgctctac cgcttcttct
    40681 aagatttcgt aatatagctc ttgattcaaa taatccgatt ccttgatctc atgatagatc
    40741 agataattga ttttttcttg aagaacagta tcaggaatca ctgtttcgaa tccaagattt
    40801 ttgacttcgc gttcatagat tccagctttc atacttcctt ctgttcctag aatcgctact
    40861 ctccctgtcg tatgctgacg gacaagttca tttgctgctt ctcttggcat atgaaggata
    40921 ggaatatccg ttgccgcttg taattcttca aaaaagtagt gtgcggtgtt acaagtcaac
    40981 acaatgaagt tcggctgcaa taaattttgt ttctcaatat catccagcag aaacggcatt
    41041 ggattttctt ctgatcgatc taaaatataa gctgtacgat caggaactgt tgcatgattg
    41101 aataagacat aattcaaata ttcttgatct tttgtagctt tcgttcggtg gttgatcaag
    41161 cgaacaaaac tttctgtcgc catcgtgccc attccgccta aaatactgaa aaaattctcc
    41221 atgaactagc cttctttcac atgaaaatac tttttgaatc ttggaatata gttatggaac
    41281 atatatttca tcaacaacca gcgcttgatt gaccggtctt tttcataaaa cacagtagta
    41341 ccgtaacgat tttctttgat catttgctca gctagttttt tgtcttcatt ttcccgagca
    41401 tattctaaaa agattttttt gggcacaccc atccataatc ttgctttatc tgattgattc
    41461 gttccatagg tcgtttcaac aaagggtttg ttaaacactc gatcttctgt gacgaaacga
    41521 gccagattca agccgttcaa tgtcacaaag aaactgctac gaccttgtct caaattgatt
    41581 tcaaataatt tatattctcc atctctagga tcatacttca tatcgaaatt ggcaaagcct
    41641 gtatattcga ttttttccaa aaatgcctta atggtttgat agattttttc gttataatct
    41701 ggcatgatca caacgtaatt accaatcgat gctggtgtag gatcttctaa cagtggatga
    41761 ccaagacaca tcatccgaac ttgatgatct tcatctacat acgcatttag cacacgcata
    41821 ttactatcat cacccgggat aaaatcttgt acaatcattt cacttttata accggcttcg
    41881 tatatccggc ctaaaattaa atcgaactct tctctagtct ctaaaataaa agcttttttt
    41941 cttccttcaa attggacaga aagatactcc acactgtttg caggtttcaa agcaactggg
    42001 aattcaaaag gcaattcctg ttccaaatgt ccatttacta acatttcttc tctgacgatc
    42061 aatgttttag gatacggaag atcatattct tcacaaactt cataaaagct tactttattg
    42121 atcagtcttt caaataaaga ataatcaata tatggacaga taaaatattc tgacagctct
    42181 tgtttatgtt gggagatcaa ttctgcatat ccatcaccac aagcaatcaa aagatatttt
    42241 ttactcttat cagaatatct ttcttttgcc aaacgaagca tcgtctcgat aaacacaggg
    42301 tctttatcaa atcctggaat aacttctaca ttgacaattt tactgtagcg ggtaggggct
    42361 aactgatccg aagcatatgc ttggcagatt ttgccgtatg cttcattaaa agaacgtgcc
    42421 ataccataaa cgttcatgtc gcttcctaat aatataggga taaattcttc attttcaata
    42481 ctgttcatca ttatctctca cttactcata atctcttgtt tttcttttcc aactacacaa
    42541 ggaatatcat accataaaga aaaaagcaat caaaggaaac tcctccgatt gctcaattct
    42601 tttttgaacg gattgaactt ataggaagtt tttgtctata ccaatcagtg tagaaagaac
    42661 taccatgtaa tgattctaga acactgatat taataaaaca agcaaaaatt cattttttta
    42721 tgttttttta actatctcag ctatctatcc tctttatacc attatttttt tcaaatagtg
    42781 acctgtataa ctttctttta cgttaatgat ttcttctggt gttccagtcg caaggatcgt
    42841 tcctccacct tctccacctt ctggtcctaa atcaatgata taatctgctg ttttgattac
    42901 atctagattg tgttcaatca ctaaaactgt gttaccagca tctactaatc tttgtaatac
    42961 atgcaacaag cgggcgatgt catcgctatg aagtcctgtc gttggttcat ctagtatata
    43021 gaaattcttt ccattagaga ttttgtgcaa ttcactggca agtttcatcc gttgtgcctc
    43081 accaccggac aatgtcgttg ctggttgccc catcgtcaca taacctaagc caacatcaac
    43141 aatcgtttgc agtttgcgat gaatctttgg aatgtgcttg aagaattcta cagcatcttc
    43201 tactgtcatt tccaaaatat cagcaatgct ttttcctttg taatgcactt ctaatgtttc
    43261 agagttatat cgtttgccat gacatacttc acaaggaaca tagacatcag gcaaaaagtg
    43321 catttcgatc ttaataattc catccccgcg acaagcttca caacgaccgc cttttacgtt
    43381 gaaactaaaa cgccctttct tataaccccg catttttgcc tcgttcgttt gagcaaataa
    43441 cccacggata tcatcaaata cacttgtata agtcgctgga ttacttctcg gcgtccggcc
    43501 gattgggctt tgatcgatat cgatgatctt ttcgatactt tcgtagccgg aaattgtctt
    43561 gaatttacct ggcttagcag aattcttatt taatttttgc gctaacgatt tctttaagat
    43621 actattgacc aatgtactct ttccagaacc agacacacct gtgactgcta caaattctcc
    43681 taatggaaat tcaacactaa tatttttcag attgttttct gaagcaccag tgatcttgat
    43741 tgctttccca ttacctttac ggcgttcttt tggtacaggg attgattttt tccctgaaag
    43801 atatttccct gtcaaagaat tttcatcatt agctacttct tcaggagtgc ctgcagccac
    43861 gatttgtccg ccttgttctc cggccccagg tccgacgtca atcagataat ctgctgccca
    43921 catcgtatct tcatcatgtt cgactacaac gagggtgttg ccaagatcac gcattttctt
    43981 taatgagcca atcagtcgat cgttgtcgcg ttgatgcaat ccgatcgatg gttcatctaa
    44041 aatatacaaa actccagaaa gattcgatcc aatttgtgta gccaatctga ttcgctgcgc
    44101 ttctccccca gataatgttc cggaagcgcg actcaaagtt agatagtcta gtcccacatt
    44161 ttccaagaat gaaagtctgt catttacttc ttttaaaatc ggtttggcaa ttactttctc
    44221 ttgttcagat aacgttaagt ttgagaagaa atctactgct ttttgaatag acaactcatt
    44281 tgtttgcccg atattcgttc cattgatttg aacagataga gcttggggat tcaatcgata
    44341 acctttacat gtctgacaag ttaattctgt catataaaga cgcatttgct cacgcgtgaa
    44401 atcactgttc gtatcatgat aacgacgctc gatattcttc aatacccctt cgaaagtcgt
    44461 ttctacatcg cgaacgccac caaaatcatt ttcataatgg aaatggaaaa gatcatctgt
    44521 cccattcaag atgatatcct gatgctcttc cggtaattct tcgaatggtg tatctaaatc
    44581 gataccgaaa ctttcacaag cctgcgctaa catttgagga taatactgag agctgattgg
    44641 attccatgga acgatagcac cttgactaag tgtcttcgtt ctatctggaa tcactaaatc
    44701 ttgatcgact tctaatttga cacctaaacc atcacagtct ggacaagctc caaaaggcgc
    44761 attgaatgag aacagtcttg gttctagttc gccaacagta aatccgcaat aaggacaggc
    44821 atagtgttcg ctaaacaaca tttcttcttc accgatcacg tcaaccagag catagccgtc
    44881 tgccaatcgc agagccgcct ctaaagaatc aaatagacga gaacgaatcc cttctttcac
    44941 aatgatccgg tcgatgacga tcgcgatatc atgttttttg tttttctcca gctcaggcac
    45001 ttcacttaaa tcatagatct caccatcgac tcgaacgcgg acgtatccct ctttttggat
    45061 tcgttcgaat atttttttat gttgtccttt tttctttacc acgatcggtg ccaacacttg
    45121 gatctttgtg cgctcaggca aagccattac ttgatctgcc atttgatcta ctgattgact
    45181 ggtaatctcg atatgatcgt tgggacaaat cggatgtcct acacgtgcaa acaacaagcg
    45241 taaatagtca ttgatttccg tcacagtacc tactgtcgac cgaggatttt tacttgttgt
    45301 tttctgatca atagaaatcg ccggactcaa tccgtcgatg ctatctacgt ccggcttatc
    45361 catttgtcct aaaaactgac gagcataagc agaaaggctc tctacgtatc tccgctgccc
    45421 ttcagcgtac agcgtatcaa atgctaggga actttttcca gaaccggaca aacctgtaac
    45481 gaccacgaat ttatctcgtg gaatcgttac atctatattt ttcaagttat gggcacgtgc
    45541 accgtgaatc gtaattttat cgttagccat gttgtcctcc tactttgaag cttttaattc
    45601 taaaatcata tctcgcacat tagcggctgt ttcaaaatcc aatgctttcg ccgcattttt
    45661 catttctttt tctaatttca tcaataacgt atctttttct tctttcgtca tttcttcata
    45721 cgagacttgt accgcttctt ttgtatcatc ttccgattct ttcgtaatag aaatcaaatc
    45781 tcggatttct ttaatgatcg tttttggaac gatcccatgt tcttcattgt acttctgctg
    45841 aatcgtacgg cgtcttgatg tttcatccat cgctagacgc atagaatctg ttactttgtc
    45901 tgcgtacatg attactttac cttcttcatt ccgagcagct cgtccaatcg tttggactaa
    45961 ggaacgttca ctacgtaaaa agccttcttt atccgcatcc aagatagcaa caagggaaac
    46021 ttcaggtacg tctaatcctt cacgaagcaa attgattcca actaacacat caaattcacc
    46081 taatcgaaga tctcgaatga tttctgttcg ttccagcgtt ttgatatcac tatgcaaata
    46141 tttgactttg atccctaatt ctttgaaata atctgtgagg tcttctgcca tttttttcgt
    46201 caatgtcgtt acaaacaccc gctggtcttt ttcgactcgt tcatttattt cgcctactag
    46261 atcatcgatt tgtcccatga ttggacgaac ttcgatcact gggtcaagca gccctgtcgg
    46321 acggatgatt tgttggataa cggtatctgt ttgttcatgt tcatatggtc ctggcgtcgc
    46381 agagacataa atgatctgat tgacatgttt ttcaaactct tctaaccgaa gtggccgatt
    46441 gtctaaagca gatggcaaac ggaaaccgta atctactagc atctgttttc tcgctcggtc
    46501 accattatac attcctctga cttgaggcat ggttacgtgc gattcgtccg ccacgatcaa
    46561 aaaatcttca ggaaagaaat ccaatagcgt ataaggcggt tcaccttctt tacgtccgtc
    46621 catatgccga gaataatttt caattcccga cgtgtagccc atttctaaca tcatttcaat
    46681 atcgtaattg gttcgctgtt ctaaacgttg agcttccaga agtttgtttt catttcgcaa
    46741 gacagttaaa cgctgttcta attccgcttt gatattcgct acggcatgct ccatatgttc
    46801 atcattcgtc acaaagtgag tcgccgggaa gattgccacg tgttccgttt ctcctaaaac
    46861 ttcacctgtc agtgcattga cttctcggat acgttcgacc tcatctccaa aaaactccac
    46921 acgtaaggca cgttcatctc ttgaagccgg aaaaatctcc acgacatcac cgcgcactcg
    46981 aaaacgaccg cgctgaaaat ctatatcatt tctttcgaat tggatactga ctaagtcacg
    47041 aatcaactga ttgcgatcta gttctgctcc ctgtcgaatc gaaactactt gtttttggta
    47101 ctcaaaaggc gaacctaatc caaaaataca tgaaacggat gcaatgacga tcacatcatt
    47161 tctttctaat aatgaactag tagccgaatg tcgtaatttg tcgatctcat catttacact
    47221 tgaatctttt tcgatatacg tatcgcttga aggcacataa gcttcaggct gataataatc
    47281 ataataagaa acaaaatatt caacagcatt gttagggaaa aattccttga attccccgta
    47341 cagctgacca gccaatgttt tgttatgggc aataattagt gttggtttat tcactttctc
    47401 aataagattg gaaatcgtat atgttttccc tgttccagtc gcacctaata agatttgtgc
    47461 ttttttcccg ccgactacgc catccactaa ttggttaatc gcttcaggct gatcaccagc
    47521 cggttggtat ttcgagacaa gctcaaagtg tcgggaggta tctctctcaa tcattcttcg
    47581 tcctcctttt cattcattcc ttttcatttt acgaccaata aaaagaaaag gaaagcaaag
    47641 gcattcctta ctaaaaaatt ataccacacc gaacatactt tcgccacttt tttatcttat
    47701 tatgcatgtt acgttttata acataaaatg ttagaaactc gcattttttt cattttttcg
    47761 agcttacagt cttgtctgat tcagcacttt tcgcctataa taataaaata ttggaaattt
    47821 aggaggttga ttatgaaaag aaagcattta tttcactcat ttgttttctt aatgacagga
    47881 cttgtgacac ttgcgtttgg acatgttgca caagctgaca acactacaac ggcagagtca
    47941 agcacaagcg agacaatgca aaaaatagag cccaaaaaag acgtatacgt aattgccagt
    48001 gactctgctt ttgctccatt tgaatttcaa aacgcaaagg gcgagtacga aggcatcgat
    48061 gtaaaattga tggaaaacat cgccaaactg caaggattta acatccgaat ggactaccgt
    48121 ggtttctctg ctgctttgca agctttggaa tcaggacaag cagacggaat gattgccgga
    48181 atgactgtaa cagatgaacg aaagaaaagc tatgattttt ctgattctta ctttgatagc
    48241 gggatccaat tagctgtcaa aaaaggagat acttcgatca agtcttatga agatttgaaa
    48301 ggaaaaacag tcggagcaaa agttggtacc gaaagtgctg aatttttaag cgaccatgaa
    48361 tctgaatatg gctattctat caaatatttt gatgctgctg atcaattgta cgacgggtta
    48421 aaagttggcg caatcgatgc aatgatggat gattatccgg taatcggtta tgcgatcaaa
    48481 caaggacaag aattggaaac accgatcaaa aaagaatctg gcggaaaata tgcatttgcc
    48541 gttaaaaaag gacaaaatcc tgagcttctt aatatgttca atgaaggatt gaaagaatta
    48601 aaaagaacag gcgaatacga taagattatt aaagaatatg tagcggatgg ttcagaaact
    48661 tccagtgagt cttccactgc tgatgaatca acatttcttg gacttatcca aaacaactat
    48721 caagcattgt tgaaaggact ttggagaaca attctcctaa ctttgatctc ctttgctttg
    48781 gctatagtaa tcggtgtgat ttttggatta ttcagtgtag caccaatacg cgctcttcgc
    48841 acaattgcta gtatttatgt cgatatcatc cgaggaattc caatgatggt tcttgcgttc
    48901 tttattttct ttgggttgcc tggtatcgtt ggatttacga ttcctgactt ccttgctggt
    48961 gttatcacct tgactcttaa cgcaagtgct tatatcgcag agattgttcg aggcgggatc
    49021 aacgccgttc ctgtcggaca aatggaagct tccagaagtt taggtctttc ttataatcgg
    49081 acaatgcaaa aaatcatttt gccgcaagcg atacgcatca tgatcccatc attcgtcaat
    49141 cagttcgtta tctcattaaa agacacaacg atcatttccg caatcggtgt agtcgaattg
    49201 ctgcaaactg gtaagatcat tgttgcacgt acaacacaaa gtacgtatgt ttacttgatc
    49261 attgcgatca tgtacttgat tttgatcaca gcattgacaa aattagcaaa agttttagaa
    49321 aagaaggtga agtaagatgg cagaaaaaat cttagttgag catttagtca aaaaatacgg
    49381 cgataacaca gtattaaacg acatcaatgt gtccatcaac gaaggagatg tcgtctgtat
    49441 cattggccct tcaggttcag gaaaaagtac atttttgcgt tgcttgaatc gtttagaaga
    49501 accttctgac ggtgaaatta ttattgacgg cgcccacttg atggataaaa gcacagatat
    49561 caacttggtg agacaacata tcggaatggt attccagcac tttaacctat tccctcatct
    49621 ttctattttg gaaaacatca ttttagcacc gatggacctg aagaaagaat ctagagaaga
    49681 agcagagaaa aaagcaatca aattgctgca gacagttggt ctagaagata aaaaagatat
    49741 gtatcctgaa atgctttccg gtggacaaaa gcagcgtgtg gctattgctc gtgctctagc
    49801 gatgaaccct gacatcatgc tttttgatga gcctacatct gcactcgacc ccgaaatggt
    49861 cggtgatgtc ttgaacgtca tgaaaaagtt agcagaacaa ggtatgacga tggttatcgt
    49921 tacgcacgaa atgggcttcg ctaaagaagt ggccaatcgt gtcatgttca ttgacgacgg
    49981 aaacttttta gaagacggaa cgcctcaaca aatctttgaa aatccgcaaa atgaacggac
    50041 aaaagatttc ttgaataaag tattaaatat ttaataaaaa ccaaaaatgc ccggtcgctt
    50101 catgacgacc gggcattttt agtttcttgt tttttcactt aactgtacca gccgcatcgc
    50161 ttgttctcct gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat
    50221 cggttcattg acgatatcaa gtacatagtc gataccacct tcagaaacta tgatgattat
    50281 cttattctaa agctggcttt tttgttggta caaacatgac aactacaaaa aaaccaggcg
    50341 aacgtatgat t
//
LOCUS       DAYNVV010000013        47813 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.013, whole genome shotgun sequence.
ACCESSION   DAYNVV010000013 DAYNVV010000000
VERSION     DAYNVV010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.013"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(70..690)
                     /locus_tag="ACGXWR_000910"
     CDS             complement(70..690)
                     /locus_tag="ACGXWR_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFK0802512.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(882..1178)
                     /locus_tag="ACGXWR_000911"
     CDS             complement(882..1178)
                     /locus_tag="ACGXWR_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFK0802513.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            1382..2032
                     /locus_tag="ACGXWR_000912"
     CDS             1382..2032
                     /locus_tag="ACGXWR_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HFK0802514.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            2048..3775
                     /locus_tag="ACGXWR_000913"
     CDS             2048..3775
                     /locus_tag="ACGXWR_000913"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802515.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            3772..5664
                     /locus_tag="ACGXWR_000914"
     CDS             3772..5664
                     /locus_tag="ACGXWR_000914"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802516.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            6368..7237
                     /locus_tag="ACGXWR_000915"
     CDS             6368..7237
                     /locus_tag="ACGXWR_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFK0802517.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            7446..8471
                     /locus_tag="ACGXWR_000916"
     CDS             7446..8471
                     /locus_tag="ACGXWR_000916"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFK0802518.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            8510..9460
                     /gene="manA"
                     /locus_tag="ACGXWR_000917"
     CDS             8510..9460
                     /gene="manA"
                     /locus_tag="ACGXWR_000917"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HFK0802519.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            9554..11257
                     /locus_tag="ACGXWR_000918"
     CDS             9554..11257
                     /locus_tag="ACGXWR_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFK0802520.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            11259..13292
                     /locus_tag="ACGXWR_000919"
     CDS             11259..13292
                     /locus_tag="ACGXWR_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HFK0802521.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            13303..13743
                     /locus_tag="ACGXWR_000920"
     CDS             13303..13743
                     /locus_tag="ACGXWR_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFK0802522.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(13943..15070)
                     /locus_tag="ACGXWR_000921"
     CDS             complement(13943..15070)
                     /locus_tag="ACGXWR_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0802523.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(15073..15750)
                     /locus_tag="ACGXWR_000922"
     CDS             complement(15073..15750)
                     /locus_tag="ACGXWR_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFK0802524.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            16014..17780
                     /locus_tag="ACGXWR_000923"
     CDS             16014..17780
                     /locus_tag="ACGXWR_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HFK0802525.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            17795..18232
                     /locus_tag="ACGXWR_000924"
     CDS             17795..18232
                     /locus_tag="ACGXWR_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFK0802526.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            18245..19396
                     /locus_tag="ACGXWR_000925"
     CDS             18245..19396
                     /locus_tag="ACGXWR_000925"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFK0802527.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(19458..20156)
                     /locus_tag="ACGXWR_000926"
     CDS             complement(19458..20156)
                     /locus_tag="ACGXWR_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HFK0802528.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(20149..21501)
                     /locus_tag="ACGXWR_000927"
     CDS             complement(20149..21501)
                     /locus_tag="ACGXWR_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurT ligase domain-containing protein"
                     /protein_id="HFK0802529.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(21724..23124)
                     /locus_tag="ACGXWR_000928"
     CDS             complement(21724..23124)
                     /locus_tag="ACGXWR_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFK0802530.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            23285..24022
                     /locus_tag="ACGXWR_000929"
     CDS             23285..24022
                     /locus_tag="ACGXWR_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HFK0802531.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            24147..24626
                     /locus_tag="ACGXWR_000930"
     CDS             24147..24626
                     /locus_tag="ACGXWR_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HFK0802532.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            24623..25390
                     /locus_tag="ACGXWR_000931"
     CDS             24623..25390
                     /locus_tag="ACGXWR_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6681 family protein"
                     /protein_id="HFK0802533.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            25620..26189
                     /gene="lepB"
                     /locus_tag="ACGXWR_000932"
     CDS             25620..26189
                     /gene="lepB"
                     /locus_tag="ACGXWR_000932"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFK0802534.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(26293..26895)
                     /locus_tag="ACGXWR_000933"
     CDS             complement(26293..26895)
                     /locus_tag="ACGXWR_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFK0802535.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            27001..27231
                     /locus_tag="ACGXWR_000934"
     CDS             27001..27231
                     /locus_tag="ACGXWR_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802536.1"
                     /translation="MPISFVKDREEKGKCVREILLDLPEWFGLPESTEKYIEESSKLP
                     LWCEKRKEEYLGFITLSQTSEDTAEIYSIVWE"
     gene            27222..27470
                     /locus_tag="ACGXWR_000935"
     CDS             27222..27470
                     /locus_tag="ACGXWR_000935"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFK0802537.1"
                     /translation="MGIKKDYHHQGLGTKLFKEAEGYAAKHYKYLQVKTVDEGHYSIY
                     DQTICFYESLGFSRLEVFPNLWDEWNPCLVLVKKLEQK"
     gene            27576..28160
                     /locus_tag="ACGXWR_000936"
     CDS             27576..28160
                     /locus_tag="ACGXWR_000936"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HFK0802538.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            28163..29236
                     /gene="prfA"
                     /locus_tag="ACGXWR_000937"
     CDS             28163..29236
                     /gene="prfA"
                     /locus_tag="ACGXWR_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HFK0802539.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            29229..30068
                     /gene="prmC"
                     /locus_tag="ACGXWR_000938"
     CDS             29229..30068
                     /gene="prmC"
                     /locus_tag="ACGXWR_000938"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFK0802540.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            30061..30240
                     /locus_tag="ACGXWR_000939"
     CDS             30061..30240
                     /locus_tag="ACGXWR_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802541.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            30262..31287
                     /locus_tag="ACGXWR_000940"
     CDS             30262..31287
                     /locus_tag="ACGXWR_000940"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFK0802542.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            31462..32706
                     /gene="glyA"
                     /locus_tag="ACGXWR_000941"
     CDS             31462..32706
                     /gene="glyA"
                     /locus_tag="ACGXWR_000941"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFK0802543.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            32859..33806
                     /locus_tag="ACGXWR_000942"
     CDS             32859..33806
                     /locus_tag="ACGXWR_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase fold domain-containing
                     protein"
                     /protein_id="HFK0802544.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            33940..34569
                     /gene="upp"
                     /locus_tag="ACGXWR_000943"
     CDS             33940..34569
                     /gene="upp"
                     /locus_tag="ACGXWR_000943"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HFK0802545.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(34708..34950)
                     /locus_tag="ACGXWR_000944"
     CDS             complement(34708..34950)
                     /locus_tag="ACGXWR_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802546.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            35071..35143
                     /locus_tag="ACGXWR_000945"
     tRNA            35071..35143
                     /locus_tag="ACGXWR_000945"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35104..35106,aa:Thr,seq:cgt)
     gene            complement(35262..35900)
                     /locus_tag="ACGXWR_000946"
     CDS             complement(35262..35900)
                     /locus_tag="ACGXWR_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HFK0802547.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(36023..36655)
                     /locus_tag="ACGXWR_000947"
     CDS             complement(36023..36655)
                     /locus_tag="ACGXWR_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFK0802548.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            37006..37305
                     /locus_tag="ACGXWR_000948"
     CDS             37006..37305
                     /locus_tag="ACGXWR_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFK0802549.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            37800..39965
                     /gene="acm"
                     /locus_tag="ACGXWR_000949"
     CDS             37800..39965
                     /gene="acm"
                     /locus_tag="ACGXWR_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HFK0802550.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(40237..40722)
                     /locus_tag="ACGXWR_000950"
     CDS             complement(40237..40722)
                     /locus_tag="ACGXWR_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HFK0802551.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    40812..41157
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            41202..41843
                     /locus_tag="ACGXWR_000951"
     CDS             41202..41843
                     /locus_tag="ACGXWR_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFK0802552.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            41862..42497
                     /locus_tag="ACGXWR_000952"
     CDS             41862..42497
                     /locus_tag="ACGXWR_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFK0802553.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            42515..43330
                     /locus_tag="ACGXWR_000953"
     CDS             42515..43330
                     /locus_tag="ACGXWR_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFK0802554.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            43649..45085
                     /locus_tag="ACGXWR_000954"
     CDS             43649..45085
                     /locus_tag="ACGXWR_000954"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFK0802555.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            45274..47721
                     /locus_tag="ACGXWR_000955"
     CDS             45274..47721
                     /locus_tag="ACGXWR_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFK0802556.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
BASE COUNT        16266 a         8278 c         9772 g        13497 t
ORIGIN      
        1 tatccaaggc acaaatgctg ctttgaagat tttttcctct gtctcttttg tatgcattta
       61 tctcaatttt taaaatgatt tacctaaagc agcagcttta tctaatgcat tttgcatcaa
      121 ctcatctgca cggtcagggt cataatcgat tccttcgatg aatagctgat ctacttgatc
      181 gatgcctaca aagtttaaaa taccttttac atattgagag gcaaagtctt gtccgttgta
      241 tacaccgcca ttagattgga tgtgcagtgc ttttttacct gtcactaatc cttctggccc
      301 gttttctgta tagcggaacg tttttccagc tacattgacg gtatcgaacc aagcttttaa
      361 ttttgttggg atatttagat tccataaggc gtttgcgata acgattttat cagcagcaag
      421 gaactgatca gtcaattcat tgaaacgagc aattttttgt tgttgacttt ctgataagga
      481 agtgaattct gcaccagcac gtaatgcttc ccaacctgat aataattctt catcgatttc
      541 cggaatatca tcgcgataaa gttccaaaac agtcacttca tcatctggat gattttcttt
      601 ataacttgtt aaaaaagacg tcaatgcctt aactgtgcgc gattcttctg cagttagggg
      661 atgacctttg actactaaaa cagatgccat atgcttacct tctcctttta ttgctatgat
      721 tgttataact atgactaaca aaatcagttt actcgaaaaa gaaaaggcta tcaagtcata
      781 ttgataaggt tgaagaataa ataactaaaa aaagacaggg tataaaagag gctgtgacac
      841 gattttttgt cacagcctct tttgaatcta acaagcaata ttcaagcaac actcgactga
      901 agagcttcca tcccaccaat gatataaaca gcacgaaaac cattagcagt aagttgatcg
      961 gctaatgctt ctgatcgcct gcctgtatag cttagaatat aataaagttt ctttggatct
     1021 agatttttta attgtcttgg caagatagca gcggggatag aaagcgagtg gcttaagtgg
     1081 ttttttgtgt aatctaaggt atttcttgta tctaaaacga tgctgtcagc atcgagaggc
     1141 aatttattga agtcttggac actaattgat tgggccattt atctcatcct ttgtttagta
     1201 tgtggctatt ttaatgggca actctcatta attcaaatgg aaggattcct cttatcactt
     1261 ttttaatgta tcggatgata atgaaaaaaa ctatgcaaat gtcttgcaaa acaggtagga
     1321 ggtgttataa tgacatagcg tcatatgaca atgtgtcatc ttgaaagaaa ggagaatcca
     1381 tatgccgaca cagacatttt tccatttgcc taaagaaaaa caaaaaagac taatcgaggc
     1441 tgcgagaatc gagttttcta gagtaccctt aaaagaagct tcgattgcta atatcgtcaa
     1501 attagcggat atccctagag gcagtttcta tcagtatttt gaagataaag aggatcttta
     1561 tttttattac tttgagacaa tgagacgtga cagctctaaa gatatgttac aactaatgaa
     1621 agaatccgat ggtgatctat tcaaaggatt cgaatcctat ttttctaaaa tgatttatga
     1681 gattttggaa ggcgagaatg cttcttttta tcgtaacttg tttatgaaca tggattaccg
     1741 tgcctcaaga aaagtcgctc ctcatacgag tcgccaaaaa acgcctcacg atccacataa
     1801 agaacacaaa caagatgcaa aagagttgct tgaattgatc gatcggacga agctgaaagt
     1861 aaaaaatgat catgaattgg aattactgat ccaattagtg atgaatactg tatttacaac
     1921 aattgcgcat tcgtatcgct tattttcaac atctgaagat tactcagtag agcaagcaat
     1981 cagtgaattc aatttgaaac tttcttggct gaaaaacgga gtatataaat agaaagaagg
     2041 gaactagatg ctaaaaatcg taaaacggat ctccttgact tcagcaattg cagctgcagt
     2101 tttcatggtg atccaagtac tggcagattt atatttgccg acacttacct ccaatattat
     2161 tgataaaggg gtagcgcaag gagatgtcga ttatatttgg catacaggtt ttgtgatgat
     2221 cggcttttct ttgatcagta tcttagctgc tatcgcaaat acattttttg ctactcgtga
     2281 atcacagaaa ctgggtaagc aattgcgtac ggatgtctat aaaaaatcag agagtctgac
     2341 aaaagatgcg tttgataaat atggaacggc ctctttgatc acaagaacga ccaatgatgt
     2401 gactcaaatc caaatggtta cacaaatgtt tttacgtatg atgatcaatg caccaatcac
     2461 gttgattggc gcgagcatac ttgcttatca aaaagatcat cagttgacaa aaatcttctt
     2521 agttgtcatc ccagtaatga ttattttgat cggcggaatc atgtactttg ctgttccatt
     2581 attcaaaagt atgcaaaaga aaactgaccg tttaaacctg gtatttcgag aaggattgac
     2641 aggggtcaga gtgattcgag cattcgataa gacacgcttt gaagaaaatc gttttgattt
     2701 agcgaataaa gattatacaa atacggcaat caaagttaat acgatcgtcg cattgatgat
     2761 gccaatgatg acattgatca tgagcggtac aaacgtagca atcacttggt ttggtggaca
     2821 ctacatagca gatatgactt tggaagtcgg taatctgatt gcatttatga cttatgcgat
     2881 gcagatcttg atcagcttta tgatgctttc cgctattttt atcatggtgc ctcgtgcaca
     2941 agcttcagct gaccgtatta atgaagtgtt ggatgaaaaa atcggtatcc atgaccctga
     3001 aaatcctaaa acagtttctt ttgctggaaa aaacgcaaca ttggccttca atcatgtcaa
     3061 ttatcgatat catggagcag aaaaacttgc attggaagat attgatttcc aagccaagtc
     3121 gggcgagatc gtcgcaatca taggggggac tggttcaggt aaaacgacct tagtcaattt
     3181 gatccctcga ttatatgaca tcgaatctgg ttcgatccaa ataaatggaa cggacattag
     3241 tgacatgact caatataatt tgcgagaatt aatgggcttt gttcctcaaa aagcagttct
     3301 gttctctgga acgatccgag acaatatgca gtatggtaag ccggatgcaa cagatgaaat
     3361 gatttggaaa gcattagaaa tcgcacaagc taaagatttt gtttcagaga tggaagatgg
     3421 cttagatagc catgtggaac aaggaggagg aaacttctct ggtggacaaa gacagcgtct
     3481 ggcaattgca cgggcattag tcaaaacagc agatatctat gtgtttgatg attccttctc
     3541 agcgttggat ttcaaaacgg atgccaatct tcgccaagca ttgaaaacga atatgaaaga
     3601 aagtatcacc gttttagttg ctcaacgagt aagtacagta atggatgcag atatgatcct
     3661 tgtgctagat gaaggaaaac tggttggcaa aggaacacat gaagaactat tagcaacaaa
     3721 cgaaacttat caagaaatcg ttcattcaca actaagagag gaggacttag catgagtaaa
     3781 acaaacacac gtccctctca tggaccagca ggcggtccag gacatggtgg acctggcaga
     3841 aatctcggtg taaaaggtga aaagcctaaa aatttctggg gaacggtacg ccgattgttt
     3901 ggctatatgt ctaaacgtat ggttgcgatc atcgctgtat ttgtactagc aatagcagcc
     3961 gtgatcttcc aaatccaaac accaaaggtc ttggggaaag caaccacaga aatattcaaa
     4021 ggtgtaatgg ctggcgctca acagatgcaa caaggccaac aagtaacaaa atttccgata
     4081 gactttgata aaatcgcgca gatcattgcg acagtaatcg tgatgtattt gatttctgct
     4141 gtattcaact ttttacagca atttattatg acacgtgttt cccaacgaac agtttatgaa
     4201 ttacgtcatg atttggaagc caaaatgaat cgtgtaccga tttcctatta tgatacacat
     4261 acaaatgggg atatcatgtc tcgagcaatc aatgatatgg ataacatcgc aagcacgctg
     4321 cagcaaaatt tgactcaatt tgtaactagt gcagtcacat tgattggggt catcgtgatg
     4381 atgctttcaa tcagctggca attgacgtta gtcgcgttat tgatgatccc tttaagcttg
     4441 atcatcgtga tgatcgtagc gccgaaatca caagtgtttt tcgcagatca gcaaaaaagt
     4501 ttaggtttat tgaataacca agtagaagaa acatatggtg gtcataccat tgttaaaaca
     4561 ttcaatcata ctgaaaaaga ccaggaagta tttgaaaaag aaaatcagaa tctgtatgcc
     4621 gctggttgga aagctcaatt tatttcggca atcatcatgc cgttgatgaa tttcgttaaa
     4681 aatctaggct atgtgttcgt cgctgtacta ggcggagtaa aagttgcaaa tgggaacatg
     4741 acattagggg atgttcaagc gttcttgcaa tatacaacac agttctctca accaatcact
     4801 caacttgcaa gtttgatgaa cactatccaa tcaacagttg cttcagccga acgggtattt
     4861 gaagtgttgg atgaagaaga gatgtccaat gaaaaatctg gccttccaga agaaaaagat
     4921 acaccataca aagttcgttt tgaaaatgtt caattcggct acacaccaga taacttgcta
     4981 atgactgatt ttaacttgga tgtcaaacct ggtgagatgg tcgctattgt aggtccgact
     5041 ggtgcaggga agacgacact gatcaacctt cttgaacggt tctacgatgt ttctggaggt
     5101 agtattcgtt acgatggtgt agatacccgt gatctttcac gtgatgaatt gcgcgcacag
     5161 ttttcaatgg tactgcaaga tacttggctg tttacaggaa gtatctatga caatatcaaa
     5221 tatgggaacg acgatgcaac agacgaacaa atcattgagg ctgctaaagc tgctcacgta
     5281 gacgattttg ttcgtaaatt gccagaagga tataacactg tattaaacga ggatgcaagc
     5341 aatatttcgc aagggcagcg tcagctaatc acaattgcgc gggcattctt agcaaatcca
     5401 gatgtcctga tccttgatga agcaacatct agtgtagata cacgaacaga aatactgatt
     5461 caaaaagcga tgaaccgcct attggaaaac cggacaagtt tcgttgttgc tcaccgcttg
     5521 tctacaatac gcgatgcaga caacattatt gtgatgaatc atggttcgat cgtagaaaca
     5581 ggaaaccacg atacattgat ggaaaaagac ggattctatg cagatcttta taacagtcag
     5641 ttttctgaag aagaagcttc atagaatagt acaaatttat tatttttttt aggggctgtg
     5701 acaaaagtcg tgtcacagtc cctttttccg aataaacggt gttcaatcag ctgtccttcg
     5761 gtattagctc aaaaaacggc aaaatatgag aagctatttt tccgttttgt atctctaata
     5821 ctcaggtcaa accgctgatt ttacaacctc ttccttaaac ggtgttctcc tgccaactcc
     5881 tcggtcacaa gtcacaatag tcaacaaacc tgagaagctg ttttttgaaa ttgctccttg
     5941 tgactcggag ttaaacggca ggctcacaac ctcttggtaa acggtgttca aaagccagtt
     6001 tctcggtatt aagccaaatt tatgcaaaaa tgtagaaagc cattttcaca aaatttttct
     6061 tactactcga aactaagcga ctttttcaca acctcttcct taaacggtgt tcaaaagctt
     6121 gcatctgcgg taataagccc aaccaaacga aaaataggag gagctatttt tgtttggctg
     6181 ttcttattac ttgatgcaga acagcttttt cacaacctct ttttataaga gtttttactc
     6241 attaatttac aaaaaacaag caaaatgcga attttctcac atttttttta acaaaatcaa
     6301 agttattgct tgaaagaaga agaatccatc gttaaaataa agcttgacgt agaggggagc
     6361 aagaaatatg aaagattttc aattgggggc tgccacctat ttaaaaagtg tagccattcg
     6421 ggtgaaagac cgagataaaa tgattgattt ttacaagaac gttgttggct ttgatttgaa
     6481 aagagaagaa aacgaattag ccattttagg aacagaagaa gctggaagtg aaatgttgct
     6541 gctggaagaa agtcctagag cgaatgatca catgggggtg atcaaaaagc tgaaccgttt
     6601 ttcattgatt atccctagca cagaagaaat ggcagatatc ctttgtcgta tccgtaaaat
     6661 gaattatcca atcaaagaag ctttagaaga tcatggacgt atggggattt tgctcgtaga
     6721 cccagaagag aatgaattgg aaatttacca tgaagagaat aagaacgacc aaagagaaat
     6781 tccagaaaca atggatcaag aagcattatt aagaaaatct gaagaaaaat tcagtaaact
     6841 atcaacaggt tcttattttg aaaaaatcca tttaaatgtt actaacttaa caaaagaacg
     6901 ccaatttctt aatcatgtac ttggtttgaa ggtacataat gaagaagagg gcatccatgt
     6961 attgaatgaa ggagatttcc atgttggttt gacagaagct agcggaggcg caattgattt
     7021 gcctacagat gaagtgattg gacttgattt tctgaaattc atgatcgata ctgaaagcat
     7081 ggaaggactg attgctcact tgcagcaact atcagttgat ttcttcttag acaaaaagca
     7141 cacagtactc acaatctatg atgctatagg aatcgaatgg tggttcgtca gtgagccaaa
     7201 agaaaagaat aaaactgaca ttcgatgcga cgcttaactt tttctttctt aacgattgtc
     7261 gcatgtctcg tcattttatg aacggtcata ctatcgctta ttctagagat agaaagagaa
     7321 aatagtatac cgggggaaac tgcgcggttt ttcgcgcagt ttttttgtgt aaaaaaggtt
     7381 gattcctcat agattaagct ttaagcttgg actgtaagaa tctgatagaa aagcaggaga
     7441 aaaagatgta tccacacacg aaacagctta ttttgaaaaa gatggaagaa ggattttatc
     7501 caggtgtagc agtcgccttc ataaaagaaa atcaagtaga aacatttaca gccggctttg
     7561 cccaagtcgt tcctgaaaag cagctgatga cagaagatct gttgtttgat gcagcctcac
     7621 tgacgaaagt cgttgcaacc acttcattag ttttacgtct attagaagat ggaaagatag
     7681 aactcgatca accgcttcat aaatatcttc ctgaatttga aaatcagaca atcactttgc
     7741 gtcatttact gacacatact tctgatatca aaacatggat accaaacaga gataagctat
     7801 ctcaggaaga attgatcgcc gcttatttga agctagaacc aggtgagcaa ctaggaaaag
     7861 aagtaaaata tacagatgcc ggtacgattc ttcttgggtt gatgctagag gaaatttacc
     7921 aagaaactgc agtggaaatc tttcaagaac aagtattgga accattagga atgatgaaca
     7981 gcttatttct tccttttcct tccaaaaaaa tcgttcccac agaacaactg ccttcgggtg
     8041 aggttttgcg tggacaaact catgatccga aagcaagagt tttggctgaa catgcaggta
     8101 acgcgggtct ctttattgat ttgaaagaca gcattacttt tgtccaaatg tatttgaaca
     8161 agggaaaaat ccgtaatggt cgttttttag aagaagagac gattgattct ttactgcaag
     8221 atcaaacacc gaaaaaaaat ggctatcgtt ctttaggatg ggacttaaaa aaggatgtag
     8281 aagacggtca tgcgattctt tttcatactg gttatacagg tacgtttttc ttgattgata
     8341 taaaaacaca agaagcgttg atatttttgt caaatcgcgt acatcctgtc gatcatcgtg
     8401 cggagtatct catatgtcga gatgaaattg ttgaaaactt tttgaaagag aaagcggtat
     8461 taccgaaata atgctataat agctatgaaa aatgagagga gtttgaatta tgcaggaacc
     8521 tatgttttta aaaccagttt ttcaagaaaa aatttgggga ggaagtcgtt tacgttcagt
     8581 ctttggtttt gatatcccta acgataaaat cggagaagat tgggcgatca gtgcgcatcc
     8641 tcatggtgtc agtgtagtag aaaatggcga attcaaaggg aaaagattag atgaactatg
     8701 gtcagaacac aaggaattgt ttggccatcc ttcagaacca gtgtttccat tattgatcaa
     8761 gatcttagac gcagaagatg atctatctgt acaagtacat ccagatgatg cctatgggat
     8821 gaaacatgaa ggtgaattag gaaaaactga atgctggtat atcatcgatg ctgaacctgg
     8881 tgcagaaatc atctatggtc atcatgcaaa gacaagagaa gaactagctg agatgatcaa
     8941 agatgggcgc tgggatgacc ttttgaagaa agtaccagtt aaaaaaggtg atttctttta
     9001 tgtaccaagc ggaacgatcc atgctattgg taaaggaatc atgattttag aaacacagca
     9061 aagttctgac acgacttacc gcgtgtatga ctacgacaga aaagatgcgc aaggacaaac
     9121 aagagagctg catatccaac aatcgatcga tgtaacaact gtccctgcga aaacaccaga
     9181 attacaaatc aaagaagtcc gaaaagggaa ttcatcgatc gtcacttatt tagaaactga
     9241 gtttttcaat gtatatgagt gggatattaa aggaatcaca tctttcaaaa aacaagcccc
     9301 ttatacattg atgacggtaa tcgaaggagc aggagacctt gtcgttgacg gaaaaacata
     9361 tccattagaa aaaggaacaa gctgtattat tccaaatggc gtttctgagt gggcggtcca
     9421 aggtgaacta gcaatcattg cgtctgaacc aggcaaatag ttcccagata gctgaaagca
     9481 gcagacggtt tttcgtttgc tgctttttct acataaaatc cgtccatcaa taaatagaag
     9541 tctggtgaaa aagatggaat acaaatggaa agcaaacaac agcagtcgcg tgtctatgaa
     9601 acaactgaga aaagctggac atcacttaaa tgaaatgatc atgccaaatc taagtctgtt
     9661 tatcgcttgg ggaatcttgt cattagcaac aaaaggtgtg tctggcgatt tgcacaccac
     9721 attagaagag gtatgccatt ggatgatcca gctgctttta cccatcttga tcagttattc
     9781 aggcgggaaa tcggtagggg gacaaaaagg ggcagtcgcc ggtgcaattg cttctttagg
     9841 gttgatcgct cgttccaatg ctccacaaat cgtaggagcg atgattatcg ggccgcttgc
     9901 cggcatcgta tatgaacaat ttgtttctag attccatgtg aaattcaagg ctggatatga
     9961 aatgcttgtc agcaacctac tagtaggact gactggtagc gttatttgta taattggaat
    10021 cgtttttatt gaaccagttt taaatagtgt tcacttgttg ctcgcctccg ttgtgtcttg
    10081 gctagtcaca atgaatctgt taccacttgt cagtctgatc ttagaacctc taaaagtact
    10141 atttttcaat aatgcaatca atcatggtgt attgacacct ttaggaatcg aattctcaca
    10201 aacagtcggg tactcttcct tatttttgat ggaggcaaat cctggacctg gtttagggat
    10261 cttactttct atcctttgtt ttgcagaaaa acaggaaaaa gtaaatgcga gtggagcatt
    10321 gatgatccat gcgattggcg ggattcacga aatctatttt ccatttgtct tgctgcgacc
    10381 gtatctattt ttagctgtaa tggctggtgg ggcaagcggc acgttgatat ttcaatggtt
    10441 agatacggga ttagctgcac ctgtatcgcc tgggtcacta ctcgtgattt ttgccaatgc
    10501 gccttatcca caactagctg gggtaagtat agggatagca atcagtacat ttgtgacctt
    10561 catttgtgca gcgatactat tgaaattacc aaataaagaa aaagagaaca aaacggtcaa
    10621 agaaagggga gaaatcttgg aaccatctat cattcattcc gtcatttttg cttgcgactc
    10681 aggtatggga tcaagtgcta tgggagccgc cctgctgaaa aagaaattag cagcagaaaa
    10741 aatcgatctt tctgtcggat acagctctat ctatgaattg aataaccaag taaatcagct
    10801 ggttatcgtg caacatgaac tagcgggtct tgcaagagaa aaagtacctc aaagtcaaat
    10861 ctatgtactg gatcactttt tggaaacaga tatcttgctg tcacgaataa aagaagcgat
    10921 ccaatttcca aagcgggaag aaaaaaaaga gatagcagat atcacagaac aaaaaacgtc
    10981 gcctgctaat attgtatttt tgtataaaaa caacagacgc ggctcacaaa ctatgggcat
    11041 gacgatttta agtcaattag caaaaaaagc gaaaaaacag tttgttatct caaaagaatc
    11101 aatagaaaaa atcaaaatcc aagaagaaac gatttatatc gcacaaagag aactagctgt
    11161 aactgaacag ctagaagaaa agatccctcg gctagttcta gttgaacatt gggtagctac
    11221 gaatgaatac gaaaaactcg tgaagggaga aatataagat gtatttatcg cccagagaaa
    11281 aacaattatt agcagaattt ctcagtagcc cgtcacctgt atctatccaa aaaatgatga
    11341 atttattgaa ggtcagtaaa cggactattt accgcgaatt agataatctt gaagtctcat
    11401 tgaaatcggt aaatgcttct ttgaaaaaag cagctagagg ctcatttgtc attgaggcat
    11461 cagaagaagt attagagcaa ttaaaagaaa atacagatgg gaaaagtaat gacttatcca
    11521 ctgctaaacg acaacacgcg attttagccg agttgttact gacgacagag ccgttgagtc
    11581 ttgctcattt catggaatca tatcgcatca gtaataccac tttttatgca gatatcaaac
    11641 agttggaaga aagtattcgc caactgcctt tggaaatcat tcggaaccag ggatacgaga
    11701 tcgaaggacc ggaaaaatac cgccggcttc tgacagcgaa tgtattagaa ttagaaatca
    11761 atgaatatga actttttcat agtatttctt tcgatgcatc actgaattat ttttttcgat
    11821 tcgttgatcc gcaacatcta tctcttgcac gcaaagtaat cggggaagaa ttgatccaaa
    11881 aaaagaccaa tctaagtgat agaaagcttg aacatttggt tttgatgctg acattgacga
    11941 tggagcgtgt gacgaaaaat catttactga caaatgagac atataatagt ctggcaaaca
    12001 aagaattact acagacagct aaacgattgt tttcacggat cgcttctgag acaaaacaac
    12061 tttatccagt aaatgagatc gtcttttttg caggattatt aaatgacttc acgaactcat
    12121 ttgatcagaa tttctttgaa gagacgttcg atacacagct tgcttattta gtaaaacaac
    12181 tgattcaaga agtaagtgaa gagacgaatg tccattttta tgaagatgaa actttgtaca
    12241 aaatgctgtt gactcattta tctggtgtgt tttcaagagc cgttttacaa gaagagacac
    12301 tgaccaatcc gattttagaa aaaatcatgg ttcaatacga ggaagttgcg aatgcaatcc
    12361 gtaaagcagt agagcggatt tttcaagaaa aaaaattatc cgaagaagag atcgcttata
    12421 tggtccttca ttttgcgaat tcattggaac gaagtccgaa agaaagcaat atcagtattg
    12481 caggattttc gccaagtgga ttagcttcta ctagcatgtt ggaactacga ttgaaaaggt
    12541 attttccctt catccaacaa attcatttct atcggattgc tgatttaaaa aaaatcgatt
    12601 tacaagaaga atatgatgtt gttatttcta catctatttt accaggatac ggtggaaaat
    12661 atattttagt ctccccgcta ctgctagaag atgaagtcaa gcagctaaaa gaagcttttt
    12721 cgcatattga gaagaaaaaa aggcaaaaaa ttacgtataa cagcaataac gagtggatga
    12781 tagaagatac ttatgaggaa acaatgcatt tcatggatca aatcaatcaa ttactcggtc
    12841 gtttttttat ccaagaactg gataatcctg agacgatttc cgaaacgatt cgcagcttat
    12901 ttccttattt tcctgaagga ctagtaacgg atgaagaggt ggttcatcgc cggctgctta
    12961 agcgatatga acaagcacct atcggtattc ctcatacaaa tatggggtta ttccatacat
    13021 ccagctcatt gatttctaaa ccgatctttt gtattttcaa tttgaaacat ccgttgacca
    13081 ttgaagggat ggatagacag ccagtcgatt tgtcccgtat gttagttatg ctggcgcctt
    13141 cgccaatcca agaaaaagac gggattcttt taggaaagat cagtggagca atcatcatga
    13201 atgacttgaa caccgagatc ttccgctcag gaaataaaga aatcgtttat cagttgttag
    13261 cgaaaatcct gattgaagaa ataaagaaat gaaggtgaaa agatgataca gctaccagca
    13321 gaaaaaatat tgctcgatca atcctatcaa aattggaaag aagcgttgac cgagatcggc
    13381 cagtggatga cccaacaagg gggaatcaaa ccggcatata tccaatcaat gatcgaaaga
    13441 caagaaaaag cgagtgtcta tatcgggaat ttcgtagcct tgccacatgg gactgacaaa
    13501 gatgaagaag tagtagaaga aggaatctat ttagtccaag tgcctgatgg tgtggacttt
    13561 ggaacaaaag aggaaccaaa aatcgcgaca ctcttatttg tagtggcttt aaaaaaagaa
    13621 catcagttag cggtgctcca agatttagcc tttttctgtt cagacatcga ccaagtaatg
    13681 gcgctcagtg atgcggaaac cattgaagaa gtccaaatga tttttgaaca tggacatata
    13741 taaccaatgt tcacagtaaa aaaagctgcc ttgcatcaag taataacttc aaccaagata
    13801 aaaataagag gagctatttt tgttgggagg ttcttattac tgcggatgca agcttttgaa
    13861 aactatttat tctagaaaac cgtttatttg aaatagggga cggtgacaag gtttttgtca
    13921 ccgcccctat tatttttgtg ttttaatagc tcttttttat atagatagtg cccataccta
    13981 tgaataataa aacgatactc catataccaa gtgtcaagat accattcatg aaagtaacct
    14041 gttctgaagc tagtggcgag aaaatatctc ctcctatgat cacattttga aaatcaacat
    14101 aagaagttgg caagtaatga ctgattgatt ctatccatcc aatcgaagaa aacaagcgat
    14161 actctgctaa gaaaagacaa agaagtgtac ctaaaagatt gactagagaa tgttcaaata
    14221 aagcagatag aagaaaactg attgtactta aaaagagcac ccacaacaac aggaacagaa
    14281 agctctggaa aagatactca tacatcggca ggattcgtat ctcctgacca atgatcgttc
    14341 ctacaggata acggaagtct cccaaaccat ttttgattat tactagtata gagacgatca
    14401 aaaatggcat cacgagactt agcatagctg caccataata aatggtaaaa cggatgctat
    14461 gtttctttac catactatcc ggtaatagat tgactagaga gattacctgc tttctttttt
    14521 cataagagat gatggaagaa agaaacaagg cggttataca taaaatcaaa aaactagaaa
    14581 tcattcctga aaaaatattt tcgtagtaat ttgctaaaga gagatgcgct ggcaagtcaa
    14641 aaatagaata tctttggatc tgatgttctt tcatataacg gagcaactcg acacgttttt
    14701 gttgttcaat gattggaatt ccttgtcttt gaccagaaat cagtcgatcc agtatatctt
    14761 tttcataatg ataagttgct tcgaccattt gctggacatt ccctgtgttt tttgcatgta
    14821 agattgcttc gatcagtttg ttgcttttct ctaaactttc cacaaattct ttctcattct
    14881 catcttcttt caacgtttca atcaaacgtt gcatctcttc atagttatga ttcagttcat
    14941 cgaattctgt ataagcaagt ttatgatcaa aaaaaagtgg gaatgcaaag agcacgacca
    15001 acaatagagg aaataaaaag tttactttgt tttttagtaa gagattgcgt tcaaatgtaa
    15061 gtaaagacat agttacacct catataattt acgataaata gctaaaatct cttccatatt
    15121 tgaggattct gtgacgattt ctccattttt tagaaaacat gctttagaac aaatcgattg
    15181 gatattcgcg atagcgtggg aagaaagaag aatcgtcttc ccctctttct gccattgtct
    15241 gatgaggcta ttcaagatat caatacttcc tgggtctaat ccgttcaacg gttcatcgaa
    15301 taacatgaca gatgaatcac tgatcaagta agcagcaagc aagacatgtt gtttcattcc
    15361 tagagacatt tttccaatcg gcaaagtaag gtactcagtc atcttcaatc gttggaaaac
    15421 agtttggcat tctactttgc tctgccaata gtatttgatc aaagtcaaat aatcaacagc
    15481 cgatagatag tcggataact gattcgttga ttctagaaaa aagaaagacc ggcgataatc
    15541 tgtataagca gtaggagaga tgttgtgaag ggacaattga tcataagttg ttggcagcag
    15601 ttgggcaatg ccattcagca aagttgtttt gccaaatccg ttcggggcaa tcaaagcagc
    15661 tacttctcct gattctacta aaagattcaa ttgtcgaatc acacgttttt taccacgttt
    15721 catgttcatg tttttgatca gtaatgtcat agataggcct ccaatataaa atttaataac
    15781 ataatagaat ggaaaacatc taaattaaat gctaacaaaa gttattgttt gcatattata
    15841 aaaaaattaa aataacagtt ttatttaaaa ttgaagtttt ctgataccga aatcttttta
    15901 ttttgctgac atactcaaac ctttggcaca aagtttcgtg ccaaagtacg actatttctc
    15961 tttttagtaa gcggatacaa ttagagtatc aaaaggagag agggagagac aaaatggaac
    16021 ggacgattcc caaaaacaac atttcgctaa aagcgagggt acaaaaatta ggcagtactt
    16081 tatcaagcat ggtcatgcca aatattggag cactgattgc ctggggtgta ttaacggctc
    16141 tatttatccc agatggttat ttaccaaatg aggctttcgc taccatggta agcccaatgc
    16201 taacttatct gattccttta ttgatcggtt atactggcgg aaaagtaatt gctggtgacc
    16261 gcggatcagt tgttggggca attgcaacga tgggtgtgat tgtcggaaca gatattccaa
    16321 tgatgctagg cgcgatgatc atgggacctc ttggtggata tgccatcaag aaatttgatc
    16381 agctattcca aaaacggatc aaatccggtt ttgaaatgct agtcaataat ttttcagcag
    16441 gtcttatcgg ttttggatta gcgttattag gtttttctgc gattggtcca gttgtcgatg
    16501 cattgactca agcaatggca aaaggtgtag agatcatttt atctgcccat ttgattccat
    16561 tgacaagtat ttttattgaa ccagcaaaaa tcttattttt gaataatgca atcaatcatg
    16621 ggattttgac accattggga actgaacaag tagcagaggc tggaaaatct attctattct
    16681 tgcttgaagc aaatcctggt ccaggacttg gcgtattact tgcttttact ttgtttggca
    16741 aaggagcagc aaaatcttca gcaccaggag ccatgatcat tcacttttta ggcgggatcc
    16801 atgaaatcta ttttccttac gttatgatga aaccgttatt attcttatca gttataggcg
    16861 gaggaatgtc aggaagtttc attttccaat tgatggatgc tggactaaga gcgccagctt
    16921 ctccagggtc gatcattgcg attctagcga tgacaccgtt caattcttac cttcctgtta
    16981 ttttgggcgt gattgttgcc gcagctgttt cgtttggtat ttctgcagta attttgaaag
    17041 cggatgcgaa agatacaaat gaagacttcg aaaaatctgt tcaagagaca aaggcagcta
    17101 agcaagcttc caaaggtgcc caaggtattc ctcaaggagc tacattctct ggcgtacaaa
    17161 aaatcatttt tgcttgtgat gcaggaatgg gatcaagtgc gatgggcgct tcgatcttga
    17221 gaaaaaaagt acaggaagca gacttgcctc aaacggtgac caatcaagca atcagccaac
    17281 tgacagatga ctcgaataca ttgatcgtta ctcaggtcga actacaagaa agagcaaaac
    17341 aaaaagcacc gagcgcgcgt tttgtctcag tagaaaactt tttgaattca cctcgatatg
    17401 atgaaatcat tcaagaatta agcagcaagc agaaaacatc agtttctgaa attgagaatg
    17461 agccagcaga agagtttctt tcagcaaaca tcaaacaaat caaagagatt ctacttgtcc
    17521 acgatgatcg ttccggatca gcaacaatgg ggatgaccgt gctcaaagat atattagaca
    17581 agaaccattt aactatcccg ttaagaaaag tcaatatcca agatttaaaa gatgaacctg
    17641 attcactgat cgtagccaaa gaaagtttag cggaaaaagt acagatggct gcacctcaat
    17701 ccattcattt atcagtcaac agcatggtca atccgcaaaa atacgaatcg attgcacaat
    17761 atttgaaaca gacagcttaa gggaggaaaa cagcatgcaa agtttgccat tcgacatgat
    17821 cgagctcaat cgatctttta aaaccaaaga agaagcgatc cgctattgcg gtcagatgct
    17881 tgtagaagca gggtgcgttg atgaggaata tatcgatgcc atggtagata gagacaaaat
    17941 gttatctgtt tatatgggga attttatcgc gattcctcat ggaacagatg aagcaaaaaa
    18001 atatgtgaaa aaatccggca tctgtgtcgt tcaagtacca gatggtgtag attttggtac
    18061 cgaagaagaa gaaaagattg cgactgtttt gttcggtatt gcaggagtcg gagatgagca
    18121 tttgcaactt gtacagcaaa tcgcacttta ttgcagtgat atggacaatg ttgtccagct
    18181 agcagacgcg ctcagcaaag aagaagtaac ggaaaatcta gcaattgctt aaggagagag
    18241 aaaaatgaga gcagtacatt ttggtgcagg aaatatcggt cgaggattta ttggagaggt
    18301 tttggcagct aatggatttg agattacttt cgtagatgtg aatcacacga tcattgatgc
    18361 tttaaatgaa agaaaagaat acgaaatcga attagcagat gaatcaaaag aaaaaatcac
    18421 tgtaaaaaat gtcaaaggaa tcaacaatca aacaaatcca gaaaaagtaa tccaagaaat
    18481 cgctgaagca gatttagtta ctaccgccat tggcccgaat atcttacctt ttattgctga
    18541 gttgattgca aaaggtatcc aagaaagaga aaaggaagga agcacaacat ctttagatat
    18601 cattgcctgt gaaaatatga ttggcggttc agcatttcta gaaaaagaag tgtataaata
    18661 tcttccggaa acatcattta ctgacaaata tatcggcttt ccaaatgcag cagtcgatcg
    18721 aatcgtccca ttacaacacc atgaagatcc tttattcgtc caagtggaac ctttcaaaga
    18781 atgggtcatt gacgatagcc aaagaaaaaa taaaaaaatc caattaaaag gggttttata
    18841 tgtagatgat ctagaaccat atatcgaacg caaactattt agtgtcaata ctggtcatgc
    18901 gactgtcgct tatacaggtg ccttgttagg ttaccagacc attgatgaag caatgcaaga
    18961 tgcgttagtt gtggcacaat taaaatcagt tttgcaggaa acaggaagtt tgctgattgc
    19021 caaatggggg tttgatgcag agcagcatca tgcgtatatt gaaaaaatca ttcatcgctt
    19081 ccaaaacaaa aatatctctg atgcgatcac acgtgtcgct cggacaccat tacgtaagtt
    19141 aggttatcaa gaaagattta cacgtccagt gagagaacta caagaacata acttgacttg
    19201 cccacatttg acggcaacaa tggggattat ttttaattac tatgatcctg aagatgaaca
    19261 aagccgtcaa ttgcatgaaa tgaagatcca tgaaaacttg gaacaattga ttcaagaagt
    19321 cacaggaatc aatgatccga aaacaatcgg gaatatcaag caaaacgtga accgttatgc
    19381 caagcaagtc gcttaaaata ggatacgaaa aaggggaatg tgacgaaatt tttgtcacat
    19441 tccccttttt cgaataacta ggctgtttgt ccttcaagat agggcagatc caattcttta
    19501 ccgtaacgtt gttctaaagc taggcggatc aaacgagctg ccaggttctc atttcttgca
    19561 aggataggtc catggaaata agaaccgaag acatttcggt aaatgacacc ttcagattgg
    19621 tcttcaccat tatttccttg accttgtacc actttcccca aaggtcgttc accttcacct
    19681 aagaaagtcc gaccattgtg gttttcaaat ccataataag tttcattgaa ttcttcgtta
    19741 tggataacga tatcaccgat aaaccggtta ttttcctgac ttaacgtgta gtgatccagt
    19801 gcactgattc cttggatctt ttctccatta gctcccatgt agtagtgacc tagcaattgg
    19861 tagccaccac aaatggctaa catgacgcca tcattttcga tatagttgat caaagaatct
    19921 ttctttttct ggatgtcttt tgaaatgatt aattgctcaa agtcttgacc accgccaaag
    19981 aaaaccaagt catatttatc agcatcaaaa ggttcatgta tactaacgat ctccgtatgg
    20041 caagaaaccc ccattttttc tgctatatat ttcaacatca aaaggtttcc gttatcacca
    20101 tatgtgttca tcaaatttcc ataaaggtgg gcgatattga gttcataatt agccacggtt
    20161 cattcctcct ttgataaatc cttgagcagc tagttcttta cgaagctgca atacagcagt
    20221 gtaagtagct aaaatataga catgctcagt tggcaattct ttgatttttt cgattacttc
    20281 tggtaattct tttgtttctg tcaatttatt ttctggaatc ccggcaactt ttagacgtaa
    20341 agtcatatct gtatgacggt ctcctccaga aataacagct gggatatcca tatcggcaaa
    20401 gttttcaaaa ttaccatccc aaatccagct gacatcgatt ccgtctgcgt aattggcatt
    20461 taataaagcc actaaagaaa atggataagg agctagacca atcatatcga ttacttgatt
    20521 gatacctaca ggatttttga caagtactaa tgtacatttt ttcccattga tattgatgac
    20581 ttcttgtcgg ccgaatactt tctcgtcata tcctaaacct tgtttgattt tatcaggatc
    20641 gacattgaag tactctgcca ctgcagtagc tgctaaagca ttgtagacat tatacatacc
    20701 gccaacttcg attccgtatt catgaccatc gatcacgaaa tctgctgaca cattgtccat
    20761 ccgtaccata tcagttaatc gataatccaa ttcaggacgt ttgaagtcac aatttggaca
    20821 gtaatatttc cctaagtttg cataagtgat cattttataa tgcaagatgt gatgacaatt
    20881 tggacataag acaccgtctg tattgtaatg agccatttgt tcacgatctt cttcatggtc
    20941 aaagccataa tattttctag gattgactgt ttcgatagaa ttgaagattg gtgaatcacc
    21001 gttactgata atcgttgcat ttggtgactt tgcggcaccg tctacaatca ttttataggt
    21061 cgtatagatt tctccatacc gatccatttg atcacggaaa atatttgtaa ataagaacag
    21121 ttctggtttc atatattctg tgactttgct caaacttgct tcatctattt ctaggacagc
    21181 aaactttttc tgtccttttt ttggttttgc ctgcaagaaa gtcgatacaa ttccctgtac
    21241 catattcgca ccagtagggt tggttagaac ttcatcgaat tgctggcgca aaatattgac
    21301 tgttaaagcg gtagtcaatg ttttaccgtt tgttccggtg acaacgacga cttggtagtc
    21361 ttttgccaaa ctatctagta tatgtggatc gactttcagc gctagtttac ctggtaaact
    21421 tgatccgcct ttaaaaaaag tttttaatgc ccattgcgac gtttttccaa ctgcaatcgc
    21481 aaaatgactg cgtattccca ttatgtaacc tccaaaaacg atttgctgac gaataaattc
    21541 aactaatcat accatatgtt gaaaaaaagg ttaaattgct tttcttattc ttaagaaaag
    21601 gttacggctg aaagtgcatg aaatcggaca aaatcgcatg atttaacaaa aaaacagctt
    21661 gaaacaaaat gattgtttca agctgctgtg attttattat tccctcttac ctatattccc
    21721 attttaaccg ataataattt tctcgcttgg atattcatag cctagatctc gtgtttcttt
    21781 tggcacgaat aacatcaatg tatatagcat tccgatccgc ccaataaaca tcagtgtagc
    21841 aatcgtgatt ttgcccacaa cagacaagtc tccggtaatc cctaaagata aaccagttgt
    21901 tccaaacgca gaagttactt cgatgatgat cgagatcagc gtttgttctt ctgtagcaga
    21961 taaaaaaacg atacaaaaga aacacatacc aagagaaagc ataaagacaa cgactgattt
    22021 tcgcacatca tcttgatcga ttctccgtcc aaaaatattg atgttatctt cacttttgag
    22081 gaaggaatat agatacaaac cgatgattgc tacagtagtt gttcgaatcc cgccgcctac
    22141 agaactagga ctgcatccga taaacatcag taaagaaaaa atgatcagtg ttgtgatttg
    22201 aaaatcaccc aaatcgtgaa tctgcagacc agcattacga gtcgtaatcg aataaaacat
    22261 cgaattgatc catttgacac tcatattgga atcttggaat aaatggtcct tttccaatag
    22321 ataaatcaag acagttcccg aaacaaacaa gataacaaaa gctaacacag ctaatttggt
    22381 aaacaaggaa aaacgaaacg gaagcttcgc attggaacgt ttgtataata gccattcccg
    22441 gcactccatc aatacaggaa aaccaattcc tccgacaaaa atcaaaaaca tgatcaggat
    22501 caagaaaaaa tagtcatgtg caaagggctt gatggaatcc ccagtgacgt caaacccaga
    22561 gttcgtgaca gccgatatcg cctgataaaa accgtaaaaa acggcatcac gccaacgatc
    22621 aaaatagcct ctgtaataaa aataaataga aaagaatgtc ccaaaaagta attgaaacca
    22681 gattaaaata gcaaaagtga tccgaatcag tcggacgata ccagacaaac gcggttgatt
    22741 catatccgtc atgatcagct gtcgctgttt cagtgtgatc cgtcgtttag aaaaaatgac
    22801 aaaagcagta gaaatcatca tgatccccaa accaccaact tgaaataata tttccagcag
    22861 tataataccg ttatcattga acacagaatt gatatcaaaa gtcgatagtc cagtcacact
    22921 cactgtactg attgccatga acagcatgtc cacaaaagaa acatggctat ctggttcgcg
    22981 aaaaatcggc atataaaata gaacgagtga taagaccgtc atcaatatat aataaaaaac
    23041 gatgatttgg atcgatgaga aatgattggc agcaaacttc tgtcctcgcc gctgcagcct
    23101 tcgaaagaat aaatcaacat gcacagtact atcctcctga caatagtcgt ttctaccagt
    23161 atacaagggg aattaggaat actcaaagaa attatcaaac agataacaat acagctttcg
    23221 attaaaatag aaatggctta taataaggaa aatcctagaa aaaagaagga ggaggaataa
    23281 caaattgatt aatgctcaac aaatcgtaga aaaaatgaaa aatcaaaaaa taaattatga
    23341 tacagttctg aaaaaaatga tcatgcaatg ggagaaagaa gaagtaaagc ctaagatatt
    23401 aatacataca tgctgtgctc cttgcagtac gcacacattg gaattcatgt ctcaatatgc
    23461 agagatcacg ttattttttt caaattcgaa tattcatcct aaaagtgagt atttgcgaag
    23521 attacatgaa caaaaacgat ttgtagacca atttaatgag aaaactgacc atcatgttgc
    23581 gctaatcgtt gatgaatacc gtccaaatga attcaccaaa atggttttaa caaaccatct
    23641 tgaaaacgaa aaagaaggtg gtgctcgctg cagtgcatgc ttcaatatgc gattagatct
    23701 tgttgcgcaa aaagcgcaag aactaggata cgattacttt ggaagtgccc tgaccatctc
    23761 gccaaagaaa aatgcagctt tgatcaatca gatcggaatg gatatccaaa agatttacgg
    23821 gacacaatac ttgccaagtg atttcaagaa aaacaaaggc tatgaacgct ctttgcaaat
    23881 gtgcaaagag tatgatattt atcgccaatg ttattgtggt tgcgtgttcg ctgccaagca
    23941 gcaaggatgc gatctgaaag aaatcaatcg ggaagcaaaa gcttacttaa aaacatcaac
    24001 cgtagttttt gaggaaaatt aaagaaatct ttcggaaaaa cgtaagaaaa aaataaagaa
    24061 tttatggtag aaataaggta gactgtataa tttgtccgta gtaaagtaag gaaacaagaa
    24121 taaatttcaa tgaaggaaga gataagatgc gaaaagtagc acctattttg aagccaatcg
    24181 ctgtattaac aatctcgacg attgtcgcga ctactacagg tattgtgaat agttccagct
    24241 accgtgcacc aagttcaagt tctagtactg tagaagaaac aacaccaact acttcagtct
    24301 cgacatctga accaacaaca acggaaagtt tgaatgaaac cactacgaca agtacatggg
    24361 acgatacaac aactagttcg tcgtatgatg agacatatac aactgacagc tcaagcgaaa
    24421 caagtaatac ggtaccagat ggcactccat cggattcaac caatccaagt acaagtccgg
    24481 atacaagtgc tagctccgaa acgataccaa gcagtacgac tgtagatgat aacacgcaaa
    24541 atgatgatgc agcacgtaca gcacagcaaa accaagattc aggaaatacc caaacgtata
    24601 accagcaagc aggtgattct caatgacatt tttactagac cttatcaacg gggtgcataa
    24661 attccttggc tatttagaca tcagtcctaa atatcttaac cgtggatata cgattttaag
    24721 tgtgattccc acgctttatt tattgagaat tgtttatgga ctttggcaaa accaaaacta
    24781 tcttcaattt ttcttatatg gacttgcatt tctagtgctt gtttatttta ctgttttaaa
    24841 tgtattttat tactttttag ataaaaacac gaaagccgat gtcactcagc tttttgtgaa
    24901 gtatttacct gatgaagcgt tcaacatcca gacagaagaa tcgatagata atggaaattc
    24961 gatcgataaa gtgaatacac aagaggtcat ggtttcttat gacgaagatt atcaattgaa
    25021 attagccgag aatatgcggt atttgattgg aaatggtgag atcaaaacaa atgaactcgg
    25081 tcgcatggat ggatttctgg tcgatagaaa tacattgtat ccttattact atgtcaagaa
    25141 aacaggagag aaagagtatg ttctaaatat tggacgaagc tactcggaca tggaaaaagt
    25201 agggaccatt cgacttgact caacagaaga cacattggaa cctgtcggat tgttcatcgt
    25261 cggcggtgat tttgtcaaag acgggttacg ctatcatgag ccttatcgtc tgaaattgat
    25321 tgcaaaaaag gcacagtcgc aggaagaacc agtggtttat agtcgtagcc aaagaagaag
    25381 acattcataa tgtgatgaaa cgccgtgtat cagtggttgc gataaaaacg tttattcgga
    25441 ataaggggga tgtgacacgt cttttgtcac gttccttttt tatataacga gaaagataag
    25501 acgaacacat cacttattct ttcctttcat ttataaacat tgtagaataa agaaagtaca
    25561 acgaagtatt gtgaaaaaac gtaataaata acgaggaaaa tacaagtagg aggtaagctg
    25621 tgaaagaatt tttgaaaaat tgggggattt tgatccttgt attagcggct attttattag
    25681 ctagagtgta cgtgtttaca ccagttactg taaacgggca ttcgatggac cctacattaa
    25741 gtgatggaca acgattgatt tcatctaaga tctcaaacta tgaacgaatg gatattatta
    25801 ctacaaagga accgggggat gaagaacgga tgattgttaa acggatcatc ggtatgcctg
    25861 gagatacagt caagatggaa aatgaccagt tgaccattaa tggcaaaaag tatgatgaac
    25921 cttatctgga tgagttcaaa aaagaatttt cagaagataa gttacaagga gaatatgctt
    25981 atagctcagg attccaagca caagcagaaa gttcatccac ctttacgagt gactttgaat
    26041 atactgtgcc aaaaggaaag tatcttgttc taggcgataa ccgcttgatt tcaaaagaca
    26101 gccgaatgtt tgggttagtc gacaaagata tgatccaagg aaaagttgtt ttccgttatt
    26161 ggcctctttc agaaattaaa atcatgtgat gaaaaaataa aaagaagctg tgacatgttt
    26221 tttgtcacag cttctttttc cgaaaattcc ttcttatttc ttggagttgc tcactttttt
    26281 tgcaatctca ttttaagctt tttggctgat ggataagaaa agcgaagcgt ttttgttcat
    26341 aaatagcttt tccccacgat ggaaggtatg actagtagca gagacaaagc ccgttttttc
    26401 caatcgatta ttcaattctt cttggctaaa gccattatgg actttcggat gactaatttg
    26461 ttcattcttg tcaaagtcta cgatgatcaa ttgaccgcca ggagctaaaa tttcataaag
    26521 ttttgtaaga atattctccg tatcaggaat gtgtaaaagt acaagtgata gaaggatgag
    26581 attagcttgg acagcaggaa attcgacaga agcatcagcg tggatcgttc ggacattttt
    26641 cagatctgct gcttggatct tttcttctgc cattttcagc atagtttctg aagcatcggc
    26701 aatgatcagt tctttgaatc tttccgcaag cggtaaacta acaagcccag ttccgcctcc
    26761 gtaatccagc aggacttttt ggtggctgtc gcgcggtaga taagtagtta gttcttcgcg
    26821 aataatcttg gctaatgctt gacggtcagg ggaatcataa tggttagcga tggaatcaaa
    26881 aatatttttt gtcatcaaat agctccttac gtaaaacttt gaaattttaa cttattatag
    26941 cacgtgaaaa gaaagaaagc atgctatact caattcaaaa agggagaatc tagaaagaat
    27001 atgccgatat cgtttgtaaa agatagagag gaaaaaggaa agtgtgtccg agaaatatta
    27061 ctagacttgc ctgagtggtt tgggcttcct gaatcaacgg aaaaatatat cgaggaatca
    27121 agtaaactac ctttatggtg tgaaaaaaga aaagaagaat atttaggctt tatcactctt
    27181 tcacagacaa gtgaagatac tgccgaaatc tattctattg tatgggaata aaaaaagact
    27241 atcatcacca aggattagga acaaaacttt ttaaagaagc agaaggttac gcagcaaaac
    27301 attacaaata tttgcaagtg aagactgtag acgaggggca ctactctata tatgatcaaa
    27361 ctatttgttt ctacgaatca ttaggatttt caaggttgga agtttttcca aatttatggg
    27421 atgaatggaa cccatgttta gttcttgtca aaaaattgga acaaaagtga gcaatagatt
    27481 taatactaat ctgtgcttga tgaaaattct cactgtaaaa aatgctgaaa atcaagtata
    27541 ataccatagg aacaaactgg aaggtgaaaa agagcatggc acaactattt tttaagtatg
    27601 gcgcaatgaa tagcggcaag acgatcgaga tcctaaaagt cgcacataat tatgaagaac
    27661 aaaataagcc agttgtctta atgacaagcg gtattgatac aagagatggt ttaggcgttg
    27721 tttcaagccg aatcggactg aaacgtaatg cgatgccgat atttgaagaa acagacgtat
    27781 ttgacgtaat tcagaaaatg gaaagcaaac cctattgtgt gctgatcgat gaagcgcaat
    27841 tcttaaaaaa gaaacatgtc attgctttta cgagaattgt ggacgaattg gatattccgg
    27901 ttatggcatt tggtttgaaa aatgattttc gaaacgagtt atttgaagga tcaaaatatt
    27961 tattgcttta tgcagacaaa atcgaagaaa tgaaaacaat ctgttggttc tgccacaaaa
    28021 aagcaatcat gaatttacat tatattgatg gaaaccctgt ttatgaaggc gatcaagtgc
    28081 aaattggcgg aaatgaagct tattaccccg tttgtcgaaa acattacttt cacccatcaa
    28141 tgattacaga aggagaataa gcatgtacga tcaattacaa gcaattgaag accgttatga
    28201 agagcttgga gaacttttaa gtgacccaga agtgatttct gatacaaagc gttttatgca
    28261 gctttcaaaa gaagaagcaa acacgcgcga aacagtcgaa gtttatcgtc gttataaaga
    28321 agtagtacaa ggaatcaccg atacagaaga actgcttggt gaaaaactgg atgatgaaat
    28381 ggctgaacta gcaaaagaag aattatctga attaaaaaaa gaaaaagaag tcttagaaga
    28441 aaaaatcaag atcttgcttt taccaaaaga tccaaatgac gataaaaata tcatcatgga
    28501 aatccgtgga gcagcaggcg gagacgaagc agcattattc gctggcgatc ttttcaatat
    28561 gtaccaaaag tatgctgaag cacaaggctg gaaaacagaa gtgatggaag ctaacgttac
    28621 cggaatcggt ggatataaag aagtgatcat gatgatcacc ggagacaacg tatattcgaa
    28681 attaaaatat gaaagtggtg cgcaccgcgt ccagcgtgtt ccttcaactg aatcgcaagg
    28741 gcgtatccat acttccaccg caacagttgt cgtgatgcca gaagctgaag aagtagagat
    28801 cgatattgaa gacaaagata tccgtacaga tatctatcat gcttcaggtg ctggcggaca
    28861 gcacgtcaat aaaacagcat ctgctgtacg tttgactcac ttaccaacag ggatcgttgt
    28921 tgctatgcaa gatgaacgtt ctcaaatcaa gaaccgtgaa aaagcaatga aaatcttgcg
    28981 tgctcgtgtg tacgataaga tccagcaaga agcacaaagc gagtatgatg ccaatcgaaa
    29041 atcagcagtc ggaactgggg atcgttcaga acggatccgg acgtataatt tcccgcaaaa
    29101 tcgtgtgact gatcatcgta tcggattaac tatccaaaaa ttagatcaga ttttagcagg
    29161 gaaattagat gagatcgttg atgcattgat catgtatgat caaacatcaa aactggaagc
    29221 tatgcaaaat gggtaaaatg acctatcgag aagtcctgtc acgggcttct tcttttttag
    29281 aggatcatgg gaaagaagca tatagtatcc aatttttatt tttggaacga aaacaatgga
    29341 aaaaacttga ttggctcctt catatgaacg aagagatttc agaagaagaa cagcggttga
    29401 tcgaaaccga tctgcgactt ctgcttgcag atcatccacc tcagtatttg ctaggatatg
    29461 cagattttta tgatcatcgg ttaaaggtaa ctgaagcaac actgatccct cgaccagaaa
    29521 cagaggagtt agtcgaatgg tgtttagacg agacgcctgg tgtaccgtta gaagtgatag
    29581 atattgggac agggactgga gcaattgcta ttagtttgaa agcagcaaga aaaaattggc
    29641 atatatctgc tgtggatctt tcagaagaag cattagaagt agcgaaagaa aatgctcaga
    29701 aagaaggaac gaaaatcagt ttttatcatg gagatacatt aggaccagta atggatcagc
    29761 aatttgatgt gattatttct aatccgccgt acatcagtcg gaatgaatgg gaactgatgg
    29821 atgaaagtgt ccggtcattc gaacctaaaa tggccctttt tgctgagaac gatggattag
    29881 ctatttatga aaaaatagca gttgaagcac caagcgtact aaaatcaaat ggaaagattt
    29941 ttttagaaat cggatttcgc caaggtgaag cagtaaaaaa aatatttcag caagcatttc
    30001 cagataaaaa agtggcgata aaaaaggatc tttttggcaa tgaacgaatg atccaagttt
    30061 atggttgaag ttgtggatga aaaatttttt atttgttttt ttattataaa aaaacactta
    30121 tttgacaagg atgtaaacga ctttttggtt tatcaacaag tttatccact attgacaaat
    30181 agattatcca caaacagtgg aaaacttgag gataaactca gacaaaataa gaatgtatga
    30241 aaaaggggtt gtggataaac tgtggaaacg aaacgatatg atgaaacaga attgcaagag
    30301 gcagccgaag cactgaaaga aggagaactt gttgcttttc ctaccgaaac agtatacgga
    30361 ttgggcgcca acgctctttt accaaacgct gtcaagaaag tgttttctgt aaaagggaga
    30421 ccgcaagata atccattaat cgtccatgtc gcctcttttg aacaagtaaa agagtatgtg
    30481 gacaactttc atccggcagc agagaagatt gtgaagaact tctggcctgg accattaact
    30541 ttgatattta agatcaaaaa agacactttg ccctcagttg tgacgggagg attatccaca
    30601 gctgcatttc gtataccgga taacaaaaaa acactagaag taatcgaact ttccggtgtt
    30661 ccgcttgtcg gtccaagtgc aaatacgtcg ggaaaaccaa gtccaacgac tgcagatcat
    30721 gtatatcatg atctacaagg aaaaattacc gggattattg atgatggagc tacgcgaatt
    30781 ggtgtagaat ccactgttct tgatttaagt gatccaacag ccatgcctat gattttacga
    30841 ccaggtgcag taacgaaaga acaaatcgaa gcagtcatcg aatctcctgt tgctattgat
    30901 cagcatcttg taaaagaaaa tgaaacacca aaagcccctg ggatgaaata caaacactac
    30961 tcacccgata cacgtgttct gatggtcaga gatggcgatt ggtcaactgc agttcaatgg
    31021 gcaaaaaata agaagatccg tgcaggtgtc atagcaagcc ccgaaattgc ggatcaagtg
    31081 cggacagata ctgcagctgt ttatatgtat aacgacaact cagtagaagc ggcggctaaa
    31141 ggattgtttg caggtctaag aggattagat gaaccaacac ttggattaga tttgattttt
    31201 gtacaagtgt atccagaaac tggattgggg aatgcttaca tgaatcgctt gaaaaaagca
    31261 gcaggacaaa attattttga aaaatgatca attggttatt gtcgcattct tttagtatga
    31321 tacaatgcta tcaagtaaat cttctatcag tgaacgaaaa actaagcgta actaatcgta
    31381 atagaagaga tacgaatatt tggcaatttg tttttgatgg gaaaaataaa attgtaggaa
    31441 aataaaaagg agctgttgtt tgtggtagat tacaaaacgt ttgaccctga tctttgggct
    31501 gcgatcgcca aagaagaaga aagacaagaa cataatttgg agctgattgc ctctgaaaac
    31561 tttgtctccg aagcagtgat ggctgcacaa ggaagtatct tgacaaataa atacgcagaa
    31621 ggttatccag ggcatcgcta ttatggtggg tgtgaatttg tcgatatcgt tgaaaattta
    31681 gcgattgacc gtgcaaaaga attattcgga gcgaaatttg cgaacgtcca gcctcactcc
    31741 ggctctcaag ccaacacggc tgcttatctc gctttggtag aaccagggga cacgatctta
    31801 ggaatggatc tttccgcagg cggacatcta acacatggat caccagtcaa cttcagtggc
    31861 aaaacctatc actttgttgc ttacggtgtt gatccgacaa cagaagttat tgattataat
    31921 gtggtacgta ttttagctag aaaacatcaa ccaaaattga tcgtagcagg tgccagtgct
    31981 tacggacgaa cgatcgactt tgcgaaattc agagaaatcg cagatgaagt aggcgcaaaa
    32041 ctgatggtag atatggcaca tatcgcagga ttagtagcag caggacttca tcctaatcca
    32101 gttccttatg cagatatcac aacgactacc actcataaaa cattgcgtgg ccctcgaggc
    32161 ggcatgattt tgacaaacga tgaagcatta gcaaaaaaaa taaatagtgc ggtatttcct
    32221 ggtattcaag gcggccctct agagcatgtg attgcgggta aagcagtagc attcaaagaa
    32281 gcattagatc ctgcatttaa agaatatagt gaacaaatca tcgccaatgc aaaagcaatg
    32341 gtcaaagttt tcaatcaagc aattggaacc agagtcattt caggggcgac agataatcat
    32401 ctgatgttga tcgatgttcg cgagttaggt ataaatggaa aagaagcaga gagcattttg
    32461 gacagtgtga atatcactgt aaataaaaac tcgattcctt ttgaaacact aagtccattc
    32521 aaaacaagcg gtattcgaat cggcacgcca gcaatcacta ctcgcgggtt caaagaagaa
    32581 gatgctgtaa aagtggctga actagttgtc aaagcattac aagcaaaaga tgataacgct
    32641 caactagacg aagtcaaaac aggtgtacgc gaattaactg aaaaatttcc gttgcataaa
    32701 aaataaaaat ttaaattcca ttagtaaaca gaaaagttca atgttgggct tttctgttta
    32761 ttttttggga aaacggattc tttgacaata tcggtgatgc tctctagtat atgaggtgta
    32821 attttagtct tcacactaaa tctcagggag gaaaagtcat gactgatcgt atctcgttag
    32881 aaaaggaagc agtagcattc agtgatgcaa atgcgcctca tccgcgtatc tatgaactag
    32941 caccggaaga aggaagagtt ttactagaag aagtacaaga atcacctgtg aacaaatatt
    33001 ccgtcgatat tgaagacttg atggtggata ctggcgaatg gggaaaactc aatattcgtc
    33061 tcgtacgacc agaagggaat atggataaat taccagttat tttttatatt catggagcag
    33121 gctgggtttt tggcagtgct caaacccatg ataaattgat cagagaactt gcggttcgta
    33181 cgaattccgt cgttgtcttt ccagaatata gtcgatcacc agaagcaaaa tatccaacag
    33241 caattgaaca aaattatgct gtgttgcaac agctgaataa attagccaag tcaaaaaatc
    33301 tggatctcga gaatctaatc gttgcaggag attcagtagg tggtaacatg gctacagtca
    33361 tgacgatctt aacaaaagaa cgaaagggcc tcccaatatc caagcaattg ctgtattatc
    33421 cagtcacaaa cgctgatttt gatacagatt cctatcatga attcggagaa aactattttt
    33481 tgacaagaga aggaatgatg tggttttggg accaatatac gacgaatgaa gaagagcgtg
    33541 ctgaaatcac agcttcgcct ttgagagcaa atataaatga actaaatgat cttccttcag
    33601 caatgatttt aacgggagaa gcggatgtat taagagatga aggtgaggct tatgcgcgca
    33661 aacttcgtga tgcaggggtt cctgttacac aagtacgctt ccaaggaatc atccatgatt
    33721 ttgtcatggt aaatgctatg gatcagacaa aggcaacgcg tgcagcaatg gcattatcta
    33781 cttcttggat caagaaaaaa gaataagctt tgcttgtccg caggaaaact tcttttcaaa
    33841 aacggatttt cttaggaaaa atggcgagtt tgactagtca atcacttgat tttgttttac
    33901 aattaaaaag aaacgacaga acaaaggaga gcttaaaaaa tgggcaaatt tcaagtgatc
    33961 gatcatccat tgattcaaca caaactaact attattcggg acaaaaactg cggaacaaag
    34021 gtttttcgtg aagtagtcga tgaaatcgct atgttgatgg catatgaagt atcacgggat
    34081 atgccattgg aagacatcgt gatcgaaaca ccgatcactg aaacaacaca aaaaacgttg
    34141 tctggtaaaa aagtagcgat tattccaatc ttgcgcgcag gtattggaat ggttgacggt
    34201 atcttggaat tgattccagc tgctaaagtg ggacatatcg gtctttatcg agatgaagaa
    34261 acattggaac cacatgaata tttcgtcaaa cttccagaag acattgatgc acgtcagttg
    34321 tttgtagtag atccaatgtt ggcaacaggc ggatcagcaa tcatggcaat cgatgcattg
    34381 aaagaacgtg gcgcgtcgaa cattaaattt gtttgtttgg tagcagcacc tgagggagta
    34441 aaagctttgc aagaagcgca tcctgatatt gacatctata cagcttctct agatgaaaaa
    34501 ttgaatgaac atggttatat cgttcctgga ctaggggatg cgggtgaccg tttgtttggt
    34561 acaaaataag taaatacgaa aaagggtgtg acacaacttt tgtcacatcc ttttttggtc
    34621 atttttaacg tttgatgcag aacagctttt tcacagcttt cgtttgcata taaaaaaacc
    34681 atcccaaaaa tgcagagatg gtcaaattca aatctttttt agttctttgt agttaacgat
    34741 tactacaccc ttactttgcg tcatcaagtt cgcattttct gcagtttcat caatctcaac
    34801 aacagcggaa tttttcaatt gctttgaaat cgttccagtt tgcgacttgc cgtgaattgt
    34861 gaacattacg tgagtattga tcttgaattt ttcaccaatt tccgatggta cgatagttgt
    34921 atcaaatttt ccaaaagttg ccattttcat aaaacctgcc tttcacatca attataccac
    34981 gttttatgaa aaatatcatg aaattaaact aattttccat cggactcttt acaatcagcc
    35041 aaatagagta tataatttct tttggataag gccagcttag ctcagttggt agagcaacgc
    35101 actcgtaacg cgtaggtcgt aggttcgatc cctatagctg gcattaaaag agaagacaga
    35161 tatatcaagg atttttaatc cattgataca tctgtctttt tgtttaaagg aaataaagta
    35221 tgctttctta gcaatagagc atgtattatt tctataaaaa tttaggagaa taaaacgact
    35281 agcaatatag ctgtgaaatc aaatatcaca tgaactgccc aacttgtaat gatcgagttg
    35341 cttttaatgg cagcttggtt gaataacaat cttgccaccc cttgtatcaa aaggatgtgt
    35401 gctacagtgt gtaaaatatt tccattatca taagtactgt aatggataaa tccaaagatg
    35461 attgctgaca agaaactagc gacaggaatg ctgaacttac tagaaaaaat agcgagaaaa
    35521 tacactgaga acaattcttc tccaagtatc atgataggca aaataataaa taataacggg
    35581 ctgaaagcct catttattgg attgcctgtt aaaccccatt tcaaaatttg ttgcaaaaat
    35641 accgagactg cggcactgat tactacattg ataaaaaaat atttggctat atttttgaca
    35701 ggagcgacag gtttcgagaa catttttttc gtatcttttt taccaaaaac aagtgtaaat
    35761 gctataaatc cagtgatagt taaagaaaaa atgctaataa tggatggcgc aaatagcaac
    35821 cctaacaaac cgagtacaac gacaatagtg cccaatatcc cttttttaag ttctattttt
    35881 tttcctaaaa tgttattcat gataataact cctactattc agtttttgaa gatagagtca
    35941 gtatacatga agagttaaaa taggcaatgt ttttttatgg atatttgtat tgctaaaaat
    36001 ttatcttata tattcatttt gattatacta cttttatttg taaaaatttt ctagcaaaac
    36061 caagtgcttg caactgatta agcgtacaat tttttagatg ttccgagcgt acttcaatca
    36121 tttcaaagga gttgctactt aaatcgatat tttttaaatc agtatcaaaa aagctagcat
    36181 tttctaaatc attagtagaa aacattattt tagtgaggga acagtctaca aaatctgcgc
    36241 ttgataagac agagtgctca aaggtacttt cttttatgtt tgaaccagat aaatttacat
    36301 agtccatttt acaattctcg aataacgtgt tcccaatata actttccatc aatttagtac
    36361 ctgttaattt acaattgaca aatttcacgc gatgcaacat gctttttgtc aatatacagc
    36421 ctgaaaaatc acagttttcg aatatacagt cggtaatctc cattctttga aaatcattgg
    36481 aagcaaaaaa tgcatacttg aaaatagatt tgtaaataat tggatggcag attatttggt
    36541 tttcgatgac ctctttttgt gaaaggatat tatacagttc aaaatcttcg ttttcataga
    36601 tatgaaaaaa ggatccttta ttcaagcttg cttcattaac tttaggaaaa atcatattta
    36661 attacctcca ttttcataaa gtcatattaa caaaagctaa accaacttac attagcagaa
    36721 aatgagatag gttttcgcct ttttcgataa cgatagtgtc gctatctctt gaaacgttct
    36781 tagaattgcc ctgagagaca caaattaggc gtaattctaa taaaaatctt agaataaaaa
    36841 tttttactga tttaatttag aatgttttta aaataaaaat cgttgccata acagtgtatt
    36901 gaaaggtttt aacaatccag taatgattta aaaaaatcta gatgtagcgt atactttgtt
    36961 tatagaatgt agtgggaaga aatatatttt tgggaggaaa tcgtgatgtc taaaagtgaa
    37021 gaaatagaaa acatggtact aaaattatat gatctcgttt taaatccaga gatcaaagaa
    37081 aaggaacgta tacttttgat agacgcaaag acaggcttag aaaaaggtca gtattatcct
    37141 aaagtcataa ataatttgga acgtagttta cgtccgttag caatcagggg agaattgtct
    37201 aaaccagtat caccgtttta tatggagata tcaacaatag gaaaatttga aaaagaatta
    37261 ggtcgaggaa tggcttcggc accgattact tttgggcatt tataaaaacg agttattcat
    37321 ctcaatgaat taaaaagtat agtcaatctc ataatgcagg ctaggttcat ttatttgaac
    37381 agagtctgta tttttttatt ctaaataaag aaacagatgt ttctttatat tgtattttat
    37441 cctttaatta acacaaaaac agctagtata aactaataat gttaattaaa agtgtatttt
    37501 atgaaactat cgttatttat taatgttgca tttttgtaag ttaaaaattg gaaatataga
    37561 ttgaaaaaat gaaagcaata agtaaaataa aatgaatata tgcgaaaaaa taatttacat
    37621 taggaaaaac cttgtaaaaa cagttttttg gcatatttat tttttataaa tatttgtaaa
    37681 ataactatca attttttagt taaaagattg gaaatgagtg ggggaggaat tgaagaaagg
    37741 atttttgaga gatgatatag taggttttat ttttagttaa aataggggag atagaaaaaa
    37801 tgaaaaagtg tagaaatatt attttatcaa tgttatttat tattactaat ataacatcac
    37861 tgattcctgt tcatgtctat gcggatgcag gcagagatat cagcagtaat gtcacttcgt
    37921 tgaccgtgga cccaacgaat attacagatg gaggaaacat aaaagtaaaa ttctcgtttg
    37981 acgaaaaaaa acaaaatatc caaccaggtg attatctttg gatcaattgg ccaagtgaag
    38041 gaaatattcg cggtgaagga ttccaaaaag aaatcccatt aatgattgaa aataaaaatg
    38101 ttggaacttt aacggtcaga aaagattctg cgcaggttgt gtttaatgaa aatattaaaa
    38161 acctagactc agtagaaggt tgggggcaat ttgagataca ggccagaaac gtaaccgata
    38221 ccggtgaaga aaatacggga ccattcaccg tgacgagcgg tgataaaaca gctactgtaa
    38281 atgtgacaaa gccagcttct ggttcttctt ctagcgtttt ttattataaa acaggagaca
    38341 tgctacctga agatactaag cacattcgat ggtttttgaa tattaacaat aacggcactt
    38401 atgttgaaca accagttaaa atcagtgatg aaatccaaag tggacaaaga ttagatccaa
    38461 gtacgtttga aattaatcaa atacacttag gtgaacagaa ggtttataga ggagaagagg
    38521 gaatccaaca atttttacaa gatttcccca gcgctacatt taatttttca gtaactgata
    38581 attacattga aataactata ccaaaaaact ttgtcaatct taggaaaata atggtgagtt
    38641 ataagacgat catagaaaac ccagaacaaa taaattttga gaatcattcg gaagcttggt
    38701 ttaaagaatt taataaacct gctgttgatg gagaaagttt caatcataca gttaaaaata
    38761 tttcagcttc tggtggagtc aacggtacag ttagaggcga attgaagatt ttcaaatata
    38821 tcaatgacac agagattggt atcccaaatg tgactttcga attaagacga gcagatgaac
    38881 agcctattca aggacagtct agtatcctgt tgacttcgaa tgaacaggga gaagctagta
    38941 tcaaaggcct gcaagtagga gactatgttg taaaagaaaa agaagcaccc aattggattg
    39001 attttgatcc actaagttca aatgaactca aattctccat aaacgaaaat gatacagagg
    39061 gagtcagttt acctatttat aacaagaaaa aggttacgaa catcacagca actaaaattt
    39121 ggaacggtgg aaccactcca agaccgagta tttattttaa attattcaga gcaagtacaa
    39181 acaattggga accagttcct gatgcagaaa caaaacgatt agacaatgga ataacttcag
    39241 tgacttggga agatatccaa cagtatgatg atagtggaaa cgaatatacg tttaaagtgc
    39301 aagaagtaga tcaaaacgga aatgattatg tcccttcagg ttatcaaaaa attgaaaacg
    39361 ggctagtcgt tacaaatgag aataaagaag tcatttcagt ctcaggacaa aaaacatggg
    39421 aagacaatga gaaccaagac ggcaaacgac cgacgacgat cacagtaaat ctattagccg
    39481 acggtcaacc gatccaacac aaagaagtaa gtgaaaaaga tgattggcgc tatcgtttca
    39541 caaatctgcc aaaatacaga gacgggcaag aaatcatcta tactgtaacg gaagacaacg
    39601 tgcccgaata cagtacgacg attgacgggt ataacatcaa aaacagttat acaccggaaa
    39661 aaacaaatat atctatacca ggtagccata taacaccgtg gaaaaatttt ccagagaaga
    39721 cagagagaga gaaaattaga aatctattct ctcaaaaatt gcaaatattt gctcatacag
    39781 gagaatccag cgaacaaaga agcaattata ttagtaagag agctgtacct aaacagataa
    39841 caaataaatc aaaaagcatt cttcctaaaa caagtagtaa aaaatctagt tttgctgtaa
    39901 tcattggttt attgatagta actatctgtg ctgggatatt cttacaaaaa tataaaaaag
    39961 tttagttaga atataatatt ttttgttaaa tatgactgaa atcaaaagaa taaaattccg
    40021 atttataatc gaaaaaagaa gcatttttat atatgcttct tttttcgtag aatcaataaa
    40081 tatggatttg gctaactatg gaagaatact cgtattagtt ttcagcgttc atactagttg
    40141 ttacattgtt tgattggcca aaagaatttc tgatatattt tgtgctaaat aaagaaaaag
    40201 acgcttgaat tgggaaataa gaaaactact ctatcattac aaattttcat aaactggcag
    40261 atgttctaag taaacaagta tcttttcaaa gtcggaaaaa tccataatca acgtagtggt
    40321 attgatattt ggatgaaagc ctacggtatc ttgacgatca atagcagcat cgatcacgac
    40381 ttggattttt ttctctttgt cgtgcatcaa tgctaatgga gtcactgtac ctgctggaac
    40441 gcctaggagg tcaggaagct gttcttcaga aacaaaagat aagcgctttt cttttaattg
    40501 ttcagctagt tgttttaaat cggcgtgctt ttcatcaggc aagatgacaa gatagatttg
    40561 ttttcctttt cttgatttca ataatagatt ttttacttgc ggaccaggta gggaaaaagg
    40621 gacatttttg actgacgtaa tcgcaggatg atcgactttt tgaaaagaga tacccagttt
    40681 ttttagtagt tcataagctt cttgttcggt tgcacgactc atcgcgcatc accctccttt
    40741 ttttattagt gtatcataaa aaagagttga caaatgaaaa ataatcatgt aaattacacg
    40801 taaagttaaa acaaatgaca tcgaaaagaa gagtagccgt taggtgtttt tagagagtct
    40861 ctggttggtg gaaagaggca gcagttaacc gtgaaacaca tcttggagtc gattttctga
    40921 agcgtatagt aggaaaatcc ggggagcccg ttacagctgc ggtcgttgct agatgaccag
    40981 ataaggctgg cttttccgtg aggagtcggt aaaaaaaggt ggaaccacgt gattaacgtc
    41041 ctttgatctt cggatcaaag gactttttgt tttcatctga acggcaacga ctgtgtgagg
    41101 ttttttctgc aaggaaaaaa taaacagagg tggaaccacg tataatacgt cctcttggca
    41161 tttgccaaga ggattttttt attttaaagg aggaaaagaa gatggagtat ttgattgaag
    41221 ttatgccgca attattagta ggagcactca caacattgaa attattttta tttaccttga
    41281 ttggctcatt accattaggg attgttttag cattaggatt gtctttgcat tttaagccgc
    41341 tacgctactt gcttcaaaca tatgtatggg ttatgcgggg aacaccgctg ttgttgcaac
    41401 tgatttttat tttttatggg ttgccgacga ttgggatcgt ttttgatcgt ttcgaagcag
    41461 cactcattgc ctttatctta aactatgcag cttattttgc agagatcttt cgtggaggga
    41521 tacaatcgat tcctcaaggt caatatgaag cagcgcaagt tttgcaatta agtccctttc
    41581 aaacggtgac gaaaatcgtc atcccacaag tgacaaagat tgttttacct tctgtaggga
    41641 atgaagttat caacttggtc aaagattctt ccttgatcta tatattaggt ttaggtgacg
    41701 taatgcgtgc tgggaaaatc gcgatggaac gcgacgcgac tttactgcct ttgctaggcg
    41761 tggcaatcat ctatcttaca ttgactggta ttctaacaat cgtaatgaaa caagttgaag
    41821 gaaaattaaa ttattaccgc taactgatag gaggaagaaa tatgattgaa ttgaagaaag
    41881 tgaacaaagc atttggtgaa aaaaaaataa tcaaagattt gaatctaatc attccagatg
    41941 ggaaaacatt agctatcgta ggtccttccg gtggcggtaa aaccacgctt ttacgtatct
    42001 tggctggctt agaaagttct gacagcggag aattttattt agacggtgta ccgttcaacc
    42061 cattcgagct taaaatgaaa gaacaagttg taggagtcgt attccaagac ttccagctat
    42121 ttccacatct gaatattttt gaaaacatta ccttagcacc aaaaatggta ttgaaacaga
    42181 caaaagaaga atacaccaaa aaagcagaag aattagcggc ttcattaggg attagtgatt
    42241 tattgaatat ctatccttat cagctttctg gcggacaaaa acagcgggta gcgattgcca
    42301 gagcattggc tatgaatcca cgggtattgg cttatgatga accaacaagt gctttagatc
    42361 ctgaattacg ccagcaagtc gagcgtttga tcctatcatt gaaagaagat ggggtaaccc
    42421 aaattattgt cacccatgat ttagtatttg cagaaaatgt cggtgatcaa ttactaaaag
    42481 tttccccaat tcattaagaa aggagaagat agagatgaaa aaaaccagtt ttctattcgc
    42541 tttgatcgca ggtcttcttc tttttgcagg ctgttcgaac aaaaaaactt cagcagataa
    42601 ttgggcgact atcaacgaag agaaaaaaat cgttataggt ttagacgata catttgttcc
    42661 tatgggattt agagataaag acgggaagct cacaggattt gatattgatt tagccaaagc
    42721 agtctttgaa caatatggga ttacggtaga ctttcagccc attgactggt caatgaagga
    42781 atttgaactg aacaatggaa cgatcgattt gatatggaac ggctattcca aaacgccggc
    42841 aagagaaaag aaagtgcaat ttacaaaacc ttatatggaa aacgatcaag tgctgatcac
    42901 acctaaagaa tcaggaatca caaactttgg acaaatgaat aataagagat taggtgcgca
    42961 aaatgggtca tctggttatg atgtatttac gaaacaacca gaagtattaa aagagatagt
    43021 caaaaaccaa gatgctgttt tgtatgatag ttttaatgaa gcattgatcg atctgaaaag
    43081 cagacgggtc gatggtctgc tgatggataa agtatacgca gactattatt tgaaacaaag
    43141 aaacgaacta gaagacttca acataacaaa aggttcttat gagagtgagg attttgcagt
    43201 tggtgcacgc aagtcagata gtacattagt gaaaaaaatc aatgaagccc tagatcaact
    43261 agagaaaaca ggtgaattcc aaaaaatatc cgataaatgg tttggcgaag atgttacgcc
    43321 gagaaattaa caaatagggg actgtgacaa aagacgtgtc acagtccctt tttccgaata
    43381 aacagtgttc tcctgccaac tccttgtgac tcggagctga atggcaggct cacaacctct
    43441 tggtaaacgg tgttcaaaag ccagtttttc ggtattaagc caaatttatg caaaaatgta
    43501 gaaagccatt ttcacaaaat ttttcttact actcgaaact aagcgacttt ttcacaacct
    43561 cctttacata tttttatttt gttgtggaag gggtttcgtg ttattctaaa agaggaacga
    43621 ttgaaggtta taggaaagga agagatgaat ggaacacaaa gaacttacct catttccaaa
    43681 agattttctg tggggctctg cttctgcagc gtatcaagta gaaggagctt ggcaagaaga
    43741 tgggaaagga gaatcagtct gggatcgatt tgtacggata cctggaaaga catttaaagg
    43801 aacgaacggt gatttggcag tagaccacta tcatcgttat aaagaagata ttgctttaat
    43861 gaaagaacaa ggtctgaaag cttaccgctt ctctgtagct tggacacgga tttttcctaa
    43921 tggacgagga gaagtcaatc aagctgggct cgctttttat gagagattga tcgacgaatt
    43981 gattgaaaac gatattgaac ctatgttgac tttatatcat tgggatcttc cacaagcatt
    44041 gcaagatgaa tataatggtt gggaatcacg tcagatcatt gaagatttca ctcattatgc
    44101 agaaacatta tttgaggcat tccgcgggaa agtccattac tggattagtt tgaatgaaca
    44161 aaatatcttc acttcattag gttatttgtt agcagcacat ccgccaggtg tgacagaccc
    44221 gaaacgaatg tatgaagtta accatattgc taatttagca aatgcatctg tcatcaataa
    44281 atttcacgag ttagaaatgc ctggaaaaat cggaccaagc tttgcgtata cgccaaatta
    44341 tccaattgac agtaatcctg aaaatgttct ggctgctgaa aatgcagaag acctgatggc
    44401 caattattgg atggatgtct atatgtgggg aaaatatccg attgctgcca tgaggttctt
    44461 agaagaaaaa ggatgggcac caacgattga agctggcgat gcagaattgc tagaatctgc
    44521 taaaccagat tttcttggga tcaattacta tcaaacggcg acgaatgcat tcaatccatt
    44581 aaacggagtt ggtgctggaa aaatgaatac gacaggaaaa aaaggttcat cagaagaaac
    44641 tggagttcct ggaatgtata aaaaagttga gaatccattt gtcgaacgaa caaattggga
    44701 ctgggagatt gacccagaag gattaaggat cggactgcgt cgtatcacaa gccgttaccg
    44761 catgccggta ctgattacgg aaaatggctt aggagagtat gacaagttga cagaagataa
    44821 acaaatccat gacgactatc gaatcaatta cttacaaagc cacgtcaaag ccatcaaaga
    44881 agcaatttcg gatggagcag aagtcctagg ctattgcacc tggtcttata cagatttgct
    44941 tagctggctg aacggttatc aaaagcgata tggatttgta tatgttgatc aagacgaaac
    45001 acaagaagga tctttggaac gatataagaa agacagttat tactggtacc aaaaactgat
    45061 tgaagaaaat ggagagaacc tttagttcac atacttaaaa caagaaggta cggctggata
    45121 tggccgtgcc ttttcttgat aaaatcattt agaaattaag aaaaactgta aaataagctg
    45181 aaaaatgaaa gaaagcgtca gttctttcaa acaaaacttt agttccctta cttttttttg
    45241 tataatgaaa cttgatgaaa tgagggataa taaatggcac aaaagaaacg gcctactaaa
    45301 aaaaggaaaa agacgaaaaa aacgaaaaag caaaaacagc agcaggaaca aatgctgacg
    45361 attggtgttg ggtttgcctt gattttattt gctgtcttcg gctttttaaa attaggtttt
    45421 ttaggaatat tgattgcaaa cggctttcgg atcattgcag gaaatactta ccaaatcctc
    45481 tgtcttttat tagccgtatt aggattttgg attgtcatta agaatacaga gttttcaatt
    45541 ggtaaaaacc gacgctggtt tggcggcata ctcttttatt tcggtatctt attattgtta
    45601 catgcccatt tatttggcaa actccatact ggggaaccaa atatcatggg gacgacatgg
    45661 gatttgttag ccagtgatat aaaacaaagt caagtagaca ataacgttgg tggtgggatg
    45721 attggagcaa tcctttatca ttttacttac ttcttgattg cacagcctgg aagttattta
    45781 gcagcagtgc tattactggc aggaggagca ttcctgttca gtaatctgga aggctatcag
    45841 ctgttaaatg gtatccaatc aattggagaa cgagtacagg aattattgga aggtgatcct
    45901 gccaagcaag ctcgaaagca agcggcaaag gaagagagaa tgaaacagcg cgcagaagcg
    45961 aaagaagcaa ggcgcttagc tgcaaaagaa gctgcagaaa aagaagctgc agaatatgag
    46021 aagaaaaaag cggtgagcca gcaaagggaa aatactgctg atgaatggca ggaaccagaa
    46081 aatacagagc cggagcagct aagttttgtt ccaatcgaca gttttcaaga aaatatccat
    46141 cctgcgaatc tagagaaacc agtaccagat acaccaaaac agaccaatac agcagaaggt
    46201 ttttcagatg agttgccaga ggatgacggt acctcattag aatttgagat tgaagcagaa
    46261 caggaaaatc aagactatga attaccgaca gttgatttgc ttgattctat accaactgtg
    46321 gatcaaagtg atgagtataa aaaaattgaa aaaaatatcg gcgtattaga acaaactttc
    46381 caaagtttcg gtgtcgatgc caaggtcgtc aaagccagct taggaccatc cgtcacaaaa
    46441 ttcgaagtcc agccggctgt aggggtaaaa gtaagtaaaa ttgtgaactt aacagatgat
    46501 atcgcgcttg ctttagcggc gaaagatgtc cggatggaag caccgattcc aggtaaatca
    46561 ctgattggta ttgaagtacc aaatggaaag atcagtatgg tttcctttag agaaatcatc
    46621 gaagcacaac caaaccaccc agataaatta ctagaagtac ctttaggacg tgatgtttct
    46681 ggacgggtac aaacggctga tctttcgaag atgcctcact tactcgtggc tggttcgact
    46741 ggtagtggga agtcagtagc aattaatggg attatcacaa gtatattaat gcgtgctaag
    46801 ccccatgaag taaaactgat gatgatcgat ccgaaaatgg ttgaattgaa tatgtacaac
    46861 ggcatacctc atctgttgac gccggtcgtg acgaacccta gaaaagcagc gcaagcctta
    46921 caaaaagtag tacaagaaat ggaagaacga tatgaaaaat tcgcggcaac cggagtaaga
    46981 aatatttctg gttacaatga atttgttcaa cagaaaaact tggaaaacgg aacgaaacat
    47041 ccaaccttac cattcatcgt agtgatcgta gatgaattag ctgatttgat gatggtagcc
    47101 agcaatgaag ttgaagatgc gattattcgt ttagcgcaaa tggctcgggc agcggggatt
    47161 catatgatcc tagctactca acgtccaagt gtggatgtta tcacaggaat catcaaagca
    47221 aatgtacctt ccagaatggc atttgcggta tcaagcggta cagattctcg gacgatcatt
    47281 gattctaatg gggcagaaaa gctcttaggg cgaggagata tgctattctt gccaatgggt
    47341 gagaataaac cgatccgtgt gcaaggagca ttcatttctg accacgaagt agaacgggtc
    47401 gttcaatttg ttacagatca gcaagaagct cattatgaag agaaaatgat gccgacagat
    47461 gaagttgaaa cgacaggtgc tccagaacag ccacaagatg agctgtttga agaagcaaaa
    47521 gcacttgtcg ttgaaatgca aacggcaagt atttcccttc tccaaagaag atttcggatc
    47581 ggttacaacc gagcagcacg tttagtagat gaactggaag ctcatggagt tgttggcccg
    47641 tcagaaggaa gcaagcctcg gaaagtattc attgagcagg aagaaacatc agaaacgttg
    47701 ccggacgata atgacatgta aaacttgtgt gatgaagggt tgaaaaacga ataaccaata
    47761 aaaagacaag gcatgatgat accaaaagaa aaaatggttt ttttccatct ttt
//
LOCUS       DAYNVV010000014        47700 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.014, whole genome shotgun sequence.
ACCESSION   DAYNVV010000014 DAYNVV010000000
VERSION     DAYNVV010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47700
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.014"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            101..544
                     /locus_tag="ACGXWR_000956"
     CDS             101..544
                     /locus_tag="ACGXWR_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFK0802557.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(550..1734)
                     /locus_tag="ACGXWR_000957"
     CDS             complement(550..1734)
                     /locus_tag="ACGXWR_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HFK0802558.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            2002..2700
                     /locus_tag="ACGXWR_000958"
     CDS             2002..2700
                     /locus_tag="ACGXWR_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFK0802559.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2707..3384
                     /gene="nth"
                     /locus_tag="ACGXWR_000959"
     CDS             2707..3384
                     /gene="nth"
                     /locus_tag="ACGXWR_000959"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HFK0802560.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3510..4043)
                     /locus_tag="ACGXWR_000960"
     CDS             complement(3510..4043)
                     /locus_tag="ACGXWR_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802561.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4340..6721)
                     /locus_tag="ACGXWR_000961"
     CDS             complement(4340..6721)
                     /locus_tag="ACGXWR_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFK0802562.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6711..7358)
                     /gene="recU"
                     /locus_tag="ACGXWR_000962"
     CDS             complement(6711..7358)
                     /gene="recU"
                     /locus_tag="ACGXWR_000962"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HFK0802563.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7422..7961
                     /locus_tag="ACGXWR_000963"
     CDS             7422..7961
                     /locus_tag="ACGXWR_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HFK0802564.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8051..8470
                     /gene="gpsB"
                     /locus_tag="ACGXWR_000964"
     CDS             8051..8470
                     /gene="gpsB"
                     /locus_tag="ACGXWR_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HFK0802565.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8492..8859
                     /gene="rnpB"
                     /locus_tag="ACGXWR_000965"
     ncRNA           8492..8859
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACGXWR_000965"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9068..10234
                     /locus_tag="ACGXWR_000966"
     CDS             9068..10234
                     /locus_tag="ACGXWR_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HFK0802566.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10280..11776
                     /locus_tag="ACGXWR_000967"
     CDS             10280..11776
                     /locus_tag="ACGXWR_000967"
                     /EC_number="3.4.17.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HFK0802567.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     LLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11857..12540
                     /locus_tag="ACGXWR_000968"
     CDS             11857..12540
                     /locus_tag="ACGXWR_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFK0802568.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            13185..14375
                     /locus_tag="ACGXWR_000969"
     CDS             13185..14375
                     /locus_tag="ACGXWR_000969"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HFK0802569.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            14477..15430
                     /locus_tag="ACGXWR_000970"
     CDS             14477..15430
                     /locus_tag="ACGXWR_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HFK0802570.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            15499..16848
                     /locus_tag="ACGXWR_000971"
     CDS             15499..16848
                     /locus_tag="ACGXWR_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFK0802571.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(17031..17354)
                     /locus_tag="ACGXWR_000972"
     CDS             complement(17031..17354)
                     /locus_tag="ACGXWR_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802572.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            17483..18646
                     /locus_tag="ACGXWR_000973"
     CDS             17483..18646
                     /locus_tag="ACGXWR_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFK0802573.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            18716..20065
                     /locus_tag="ACGXWR_000974"
     CDS             18716..20065
                     /locus_tag="ACGXWR_000974"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFK0802574.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(20110..20541)
                     /locus_tag="ACGXWR_000975"
     CDS             complement(20110..20541)
                     /locus_tag="ACGXWR_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFK0802575.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            20929..23571
                     /gene="alaS"
                     /locus_tag="ACGXWR_000976"
     CDS             20929..23571
                     /gene="alaS"
                     /locus_tag="ACGXWR_000976"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HFK0802576.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            23771..24367
                     /locus_tag="ACGXWR_000977"
     CDS             23771..24367
                     /locus_tag="ACGXWR_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFK0802577.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIVTIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            24489..25637
                     /locus_tag="ACGXWR_000978"
     CDS             24489..25637
                     /locus_tag="ACGXWR_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFK0802578.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(25675..26088)
                     /locus_tag="ACGXWR_000979"
     CDS             complement(25675..26088)
                     /locus_tag="ACGXWR_000979"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HFK0802579.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            26167..26598
                     /locus_tag="ACGXWR_000980"
     CDS             26167..26598
                     /locus_tag="ACGXWR_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HFK0802580.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(26697..26930)
                     /locus_tag="ACGXWR_000981"
     CDS             complement(26697..26930)
                     /locus_tag="ACGXWR_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFK0802581.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            27113..28783
                     /locus_tag="ACGXWR_000982"
     CDS             27113..28783
                     /locus_tag="ACGXWR_000982"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HFK0802582.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            28930..29316
                     /locus_tag="ACGXWR_000983"
     CDS             28930..29316
                     /locus_tag="ACGXWR_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802583.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            29303..30001
                     /locus_tag="ACGXWR_000984"
     CDS             29303..30001
                     /locus_tag="ACGXWR_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFK0802584.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            30006..30470
                     /gene="lspA"
                     /locus_tag="ACGXWR_000985"
     CDS             30006..30470
                     /gene="lspA"
                     /locus_tag="ACGXWR_000985"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFK0802585.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            30467..31378
                     /locus_tag="ACGXWR_000986"
     CDS             30467..31378
                     /locus_tag="ACGXWR_000986"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFK0802586.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            31613..32152
                     /gene="pyrR"
                     /locus_tag="ACGXWR_000987"
     CDS             31613..32152
                     /gene="pyrR"
                     /locus_tag="ACGXWR_000987"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HFK0802587.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            32166..33449
                     /locus_tag="ACGXWR_000988"
     CDS             32166..33449
                     /locus_tag="ACGXWR_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFK0802588.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            33462..34388
                     /locus_tag="ACGXWR_000989"
     CDS             33462..34388
                     /locus_tag="ACGXWR_000989"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HFK0802589.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            34407..35687
                     /locus_tag="ACGXWR_000990"
     CDS             34407..35687
                     /locus_tag="ACGXWR_000990"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HFK0802590.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            35692..36768
                     /locus_tag="ACGXWR_000991"
     CDS             35692..36768
                     /locus_tag="ACGXWR_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HFK0802591.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            36773..39958
                     /gene="carB"
                     /locus_tag="ACGXWR_000992"
     CDS             36773..39958
                     /gene="carB"
                     /locus_tag="ACGXWR_000992"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFK0802592.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            40012..40788
                     /locus_tag="ACGXWR_000993"
     CDS             40012..40788
                     /locus_tag="ACGXWR_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HFK0802593.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            40785..41717
                     /locus_tag="ACGXWR_000994"
     CDS             40785..41717
                     /locus_tag="ACGXWR_000994"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HFK0802594.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            41714..42430
                     /gene="pyrF"
                     /locus_tag="ACGXWR_000995"
     CDS             41714..42430
                     /gene="pyrF"
                     /locus_tag="ACGXWR_000995"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HFK0802595.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            42437..43066
                     /gene="pyrE"
                     /locus_tag="ACGXWR_000996"
     CDS             42437..43066
                     /gene="pyrE"
                     /locus_tag="ACGXWR_000996"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HFK0802596.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            43054..43368
                     /locus_tag="ACGXWR_000997"
     CDS             43054..43368
                     /locus_tag="ACGXWR_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802597.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            43406..44047
                     /locus_tag="ACGXWR_000998"
     CDS             43406..44047
                     /locus_tag="ACGXWR_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbR-like 5'-deoxynucleotidase"
                     /protein_id="HFK0802598.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            44090..44782
                     /locus_tag="ACGXWR_000999"
     CDS             44090..44782
                     /locus_tag="ACGXWR_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HFK0802599.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            44779..45681
                     /locus_tag="ACGXWR_001000"
     CDS             44779..45681
                     /locus_tag="ACGXWR_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFK0802600.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(45839..47545)
                     /gene="efbA"
                     /locus_tag="ACGXWR_001001"
     CDS             complement(45839..47545)
                     /gene="efbA"
                     /locus_tag="ACGXWR_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HFK0802601.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
BASE COUNT        15522 a         8347 c        10270 g        13561 t
ORIGIN      
        1 tttttcttgg tttcagattg ggttttccta caaaatattt ttatctttgt tgaataggaa
       61 acaaaaaaac aatataatga aagaaaaaga aggtgtagaa atggataaaa gacaactgct
      121 aatagaagaa tatctggatt tagctaatga gattattcat cgtaataaac cagaaatgga
      181 aaaagaattt gcaggattta ctctaaatga actagaagtg attgaacata tcgggaaaat
      241 ccctgatcct aacgtgacaa aattagcgaa tgctagttac atgactagag gagccatcag
      301 taagctaaca aaaaaactga tagctagagg gatcataaac acttatcaaa gcgaagagaa
      361 taaaaaagaa atctattttc aattgacgcc aatcggacaa aaaataagga atagacacga
      421 gcaactccat caaaaatggg tacagcgaga tgctactgta tttgaaaata tgtcaaaaga
      481 agaatttgac acagtatttc gttttatcgg tcgatacaga gaatttatac gaagtagcaa
      541 atgaagctac tattttttat tgtagtgata ataggcaaaa atcataagca aaaatccgaa
      601 taccgtcgga agaaatggtg ctgcagcata aagctgtcct gcgattagcg ggccgatgac
      661 gcgcgataga gattgtatac tttgggtacc gcccattaca agaccttgct ggttatctga
      721 gacagaattg gatagttggc cattgaatac aggagtaaaa atagaatcac cgaaaccata
      781 acagataatc ccaaataaaa acaaaatcgg cagtagaaga attccagata atgtgatgaa
      841 tagataggcg aggatttcac tgaacatccc tattcttgtg atctgctgtt ctgaaaattt
      901 tttgagcaat cgaggcataa tgaacaattg cgagacagta tccaagattc caatcaaaga
      961 gaagcttaaa ccaaccaacc cagccttcca ctgaaaggcg tcaatcgaaa attgagaaaa
     1021 gatagattga agagagccag ctgccaacca aacagcaaaa cctgctgtca ataaaggaat
     1081 aacggatgaa atcttgaata attgttgtaa ttggtgaaaa ggtcttacat gggagaaact
     1141 taaatctact gaacgttttt ttattggaag gctttctagc ataaatgtgt agccataaac
     1201 ggcatttaag aaagtaaaga gtgctccaat aaatatagga acagaattcc ccaactcagc
     1261 taatagaccc cctataatag gacccagcgt tgttcctata ccgactaaag cacccatcca
     1321 tccaaaaact ttggttcttt cattaggttc cgtgatgtcg gcaaagtaag catataaggt
     1381 ggagatttct cctgccgtca atccttcaat gatacgacca aggaacaaca tccatatcga
     1441 atttcctaaa ccaaaaagca aatatccgat acttgatcct aataaactga taataaggat
     1501 cggatgacgc ccaaaatgat cacttaagct accgagaatg ggggcagata agaaggcagc
     1561 tagagcataa acagacatga gcaaagtgat atagaaagct tgctgatgta tggagtgaga
     1621 ataaggcagc gttaaaaacg gaagtacagg actgacgata gtaaatccta atccagtgaa
     1681 taagacagag acgtatccaa aaactttaga atgtttattt gtgaaactgt acatgtaaaa
     1741 actcctttat gcaataatgt taacttggaa acaaaaatag tgtatagtaa ttttgtttcc
     1801 ttgtcaacat tctaaggaac agcgaaatct acttaattta tttattccga aaagtgaaga
     1861 tacgcatcaa aaacatgaac aaacaaaaat caagtagacg acattgtaaa tctgaccgat
     1921 cagtgaagta aatagaaaag aaacctgttc ttgcttccca tgtttttttt acgtatactg
     1981 tgattgagcg gaggagaaat catgttgaat ttagaaaatt acttaagcgc tggacaaaca
     2041 gtcatatcta atcttttact taaaaattat cataggatcg gtctacaatc tgaagaattt
     2101 ttatttgttc tacagttgca tatggcacag cttgaaggag atactttccc tgatttgcag
     2161 atgattgcta tggatatggg aatcaaacaa gatcagattt ttcaaatact ggatcgtctc
     2221 gtaacaaatg gatttatcaa gatagaaacg acgattgtca acggtaaaaa agcagatcga
     2281 tataatcttt accccatcta tgatctatta ggtgagtatt taaaaacaca agaaaaaaaa
     2341 tacgaagaaa aaacacaaga aaaagaaatc cagtcagtgt atcaattatt tgaacaagaa
     2401 tttggacgcc cgctttcttc gatcgagttc cagcggatcg gacaatggct agaagaagac
     2461 cattatcagc cggaaatttt gaagctagca ctgcgggaag ccgtattaaa tcaggcttat
     2521 agttttaatt acgttgaccg cattttgcta tcgtgggaaa gaaaaaatct acgtacaaaa
     2581 caacaagtgg aagaagacca aaaacgaaga aaacagcagc ttcttcaaag agaagtagaa
     2641 cagtcagctc aacaagaaga attgccgaaa gtctcactga aaaattggtt ggaggagtag
     2701 cggaatatgt taagcaaaca aaaaacaatg gaagctctag aaacgatgta tggaatgttt
     2761 cccgaagcac atggagaact caagcacaat aatccatttg agttattgat tgcagtgatc
     2821 ttaagtgccc aggcgacaga tgtatcagtg aataaagcaa cgccagattt gtttgcctct
     2881 tttccgacac ccgatgcgtt agcagaagct tcaatcgatg aaatcattct taaaataaaa
     2941 acgattggtt tgtatcgaaa taaagcaaaa aacatcaaag cgtgtgcaca gcagctgatt
     3001 gaacgtttcg atgggcaagt gccaacgtca agagaagaat tgatgtctct tcctggtgta
     3061 ggcagaaaga cagcaaatgt cgtattgggg gatgcattcg ggataccagc aatcgcagta
     3121 gatacccacg tggaacgtgt ctcaaaacgc ctgaggatct gcaaactaga tgctacggtc
     3181 atggaagtag aagaaacact gatgcggaaa gtaccacaag aattatgggt aaagacacat
     3241 catacactga ttttttttgg tagatatcat tgcacggcaa gaaatcccaa gtgcgaggta
     3301 tgtcctttgc tatcaatatg tcaagatggg aaaaatcgga tgcgtctaaa agaaaaggcg
     3361 ctaaaaaaga aaccacgcct gtagacgtgg tttctttaat tgcaaataaa tgtatgaatt
     3421 atcttgttat tatggagaaa agctgtttcg tttatctttt ttgcatgaaa aagtaaatgt
     3481 acatactcag tagctaggat ggtaacttat tacaatttat tgcgataaaa ataaaagttg
     3541 ttatttttat tgggaaaata cccgatgtag aaaataatgc cttccaatat acctataaaa
     3601 taagtccagt attccaaagg attatataaa taagtgacgt atctatctaa aggtgtaata
     3661 aaaatgataa gtgataataa aaaaatacca tttataacta aacataaact aatggatttg
     3721 ggcggtttca ggctcatcag aaaaatatag attctggtga acaacaacca taaaaaagtg
     3781 agaatcattg catgagagct tctttccata aattttcctt taagagtagt gcttaaaagt
     3841 acagaaaaaa taataaatgc aaggatagga gcaattaaag taaatttatt taataataaa
     3901 caaaattttt cagctttttt attcttggaa taacgaggta ttgttttcga taaaaaaaga
     3961 tggtgcagac aaattatgat aattaagcat actatcagat aactcaaaat gaagccttct
     4021 ttcaaaaaat tattcaaaac catatattgt attttttatt tgataataac aatgggatta
     4081 ttaagaagtg gcactaaata aaagactagt gtgtatttag ccgatttaat tataaacaag
     4141 taaatggata aagtatatgt aatgataaaa gaaaaatgga ttttctaatt tttaagctaa
     4201 atgttagatc acacatgtat atgctggata gtcttataaa aaatcatgta atacagcttg
     4261 gtacatgatt tttatttgta gctgtttttt acatagacac aaaaaagaaa ccacgcttgt
     4321 agacgtggtt tcttttttac tatctgtttc cagaagctga ggtgctgctg gatggtgtat
     4381 ggtcatttgc agcatccgct ccgctagttg ctggctcact ggaagaagca ggaggagcag
     4441 atgaagacgg tgtcgagctt tcttcggatg aagaagaagg aaccgttgtt gaagacgctg
     4501 gctcgcttgt ttctgctgtc gtgctttctt ttgaggactc agcagttgat tcgctttgac
     4561 tagtagagct agagctttga gtcgttgtct ctgttgttga gcttccagga gtctggacat
     4621 agctggaaga tggaatagtt gttgatggtg taattgcatt cgatctagct gtatattgat
     4681 ctttgtagta cagttcaccg cccacacgaa ttaatccgct tggcatctcc cagtctgtat
     4741 ttgtcacgtt agctgaaaca tactgcataa gctcgcgata aacatcagag gctacgtgtg
     4801 acgattctga agtgacaggt gtcatttttt tattgtaacc tgtccacacg gaaatcgaat
     4861 aatttggcgt atagcccgca aataggatat ctggatacac cccagaagaa ataccaagtt
     4921 ttgcatactc gtcatctgtg taattggatg ttccggtctt accggcttga tataacccag
     4981 cgatttgcgc attcgtacca gttccttcag tgatcgtatc ttttaaaatg tctgtgatca
     5041 tataagctgt ttctggagac atggctgttt ttccatctgg ctcataagtt tcttctgttc
     5101 cgtcttggaa gacgatttta ttaacatatt gaggtttgta ataagtccct ccattggcga
     5161 aagccgcata ggctgctgcc atttttaagg aagaagctcc gtattttgtc ccatcttgtt
     5221 cttccgtatt actagagatc gcattcgatt gatggatcgt actgtattcg atcccaagat
     5281 tttttaagaa agaagccact ttatctgaac cgacttcatt gaataatttg actgctggaa
     5341 cattacggga taagtaaagt gcttggcgta aagtaatggt gcccatatat tgattatccc
     5401 agtttcctac aggagtcgaa gtcccttcat agttatacgg tgcgtcagta atagtttttc
     5461 cagtagaata tttcaaatat tcaaaagctg gtccgtaatc tgtgacaggt ttcatcgtag
     5521 aaccaaaatc acgggaagta ttcactgcta agttgttgcc taaagttacg tcttctgcga
     5581 tgtgacgtcc gccaatctgg gcttttactt tcccggtatt ggtgtcgata agggtggagg
     5641 caacttgcat ctcgtcgtct gggtaagaga catactgatc cgtgttgacg atatcatata
     5701 gtttcttttg ggcgtccaga tccaaattcg tataaatctc taaaccgtct gtgtagacat
     5761 tcttatctgt tttttcttgt acttcattga tgacttcttt gacataatta tcgacgatct
     5821 tagtattgtc atcggattga gttagttctt gcagaccatc cgttaccggt acattaacag
     5881 cttgatcata ttctgtttga gagatttttt cgttttgaag catcgtatac aaaacagtat
     5941 ctcgtctttt cttcgcctga tctggataaa cataaggatc ataggcggaa ggggcttgag
     6001 gcatcccagc aagcaatgct gtttgcggta aagaaagttc tgataatttc ttaccaaagt
     6061 acatctcaga agctgtctcc atcccgtaca agccgtttga catatacact ttatttacgt
     6121 agtaggtcaa gatctcttgt ttcgattttt tttgttccaa tcttacagcc atccacgctt
     6181 cttgggcctt gcgtttcaga gtctgatcct cggcactggt ggagaagaag gaaagtttga
     6241 tcaattgctg tgtcaaagta cttccgcctt gcagtccgcc agaggtaaag ttagagaggg
     6301 cagaaccgat gatccgaata gggtcaaccc cgatgtgttt ataaaaacgg cgatcttcta
     6361 ccgacacgat cgcatcttct aatgttttcg gtaattcatt cgcagaaatt ttttcacgct
     6421 tttctgcgcc taaatcttcg aatagttcgc catcttgtgt atatagtttg gaagatacgg
     6481 tagcgtctaa ttttttatcc gtcaattcgg gcgcatcttt tgcgtaatac cagaaaagtc
     6541 ctacacctgc taaaaagagg atacagaaaa atgagagtat tcctaaaagg atcttgataa
     6601 ataatccttt tttatgtgtt ccagaggact ttccagaacc tttgccagaa ttcttcttca
     6661 cactcttttt aggagtaggc tgtttctgtc gtctagagct tctagtttgt tcatttgcca
     6721 ttcttgcttt ctccttcaat agataatgtt gataaataga agtcaaccgc gtccaaataa
     6781 ggaatccgcg gagaaatacc agttttgatc tctattccta gttcttcgat caaagataaa
     6841 ggtagtgatt tgcgtccttt ttccttttgg gcgtcccagt aagcaatcaa atgaacacta
     6901 ttcaaataaa aacagcgctt caaagacgaa aaccataaca agacaaagca gaccccattt
     6961 tgttcgaggc atgctttcat atgttcgatt tgatgggcat ggaagttttt aaagggaaaa
     7021 gatgttttgt tcttggtttc ttttgcttca aagtccaagt aaaagcctcg atagacgcca
     7081 ttatagtctg tagttgaggc ttgggtaaag taggcttcct tgatcacagc agcacttctc
     7141 ttaggatagt ctactttcac gatttggata ggggtaggct ttttatggat aaccgccaac
     7201 ccgcgggaaa gataatattt attactttca ttgattgctt cttcaaagcg catcccccga
     7261 ttgccgaatt cagtgatctg atttcttttt tcttgaattt tttcgacggg agaggcattc
     7321 ttataataag gttggccatt tggatagcgc aataccatct ttaatcacac tcctaggcca
     7381 cattatagca aaaaagcgga tagaaagaaa aggaatctga gatggataag tcaaaagtaa
     7441 tctatgtgtc tgggtatcga agtttcgaac tcggtgtttt taaagaaaat gatcctaaaa
     7501 tccaagttgt taaaaatgtt ttaaaaaaag aactccatca gttagcagaa gaagggctgg
     7561 aatgggtact tgtcagtggg aatttgggcg tcgaactatg ggctgtgcaa atagtagcgg
     7621 aattgaaaga agaatatccg gaactatctc ttggtatttt gtatcctttt tctgattttg
     7681 gtaataactg gaatgaaggg aaccaagaaa aaaaacaatt agcagaacaa ttagcagatt
     7741 atgtcgaagc tgttagccat caaccctacc aatcacctag tcagctaaag aatcacactc
     7801 gttttatact tgagcataca gtgggctgtc tgctgatcta tgatgaagaa ttccctggaa
     7861 aaacgaagta tttttttgaa gatgcacaga attaccaagc agatcatccc tacgaaattc
     7921 ggctgatcag tatggacgat cttcaaaatt ttagtgaata atcgatattg tgtttgattt
     7981 atcaactttt ttcctataca atgaaaaagg tagaaatgtt attacgtaaa tgaaaactag
     8041 aggtgtaaat atggcgaatt tggtttatag tcctaaagac attttacaac aagaattcaa
     8101 aacaaaaatg cgcggctatg atcccgttga agttgatgaa ttcttagaca atatcatcaa
     8161 agattatgaa acttacagca aagaactcct tgctttacaa gaagaaaacg atcgattgag
     8221 tgcaaaagta gctcaattat ctaaaactca aggagcagct caaacacgcg tgcaacaaac
     8281 agaggcacca aagagcgcag cagtgaccaa ttttgatatc ttaaaacgct tgtcaaatct
     8341 tgaacgtgaa gtatttggta aaaagcttga tcaacaagca agtgcagtca aaccagcaca
     8401 acctaatcca aataactaca caaatgcaga cacaagctta gatgataatg aaaaaacacg
     8461 tcaattttaa tttttgatta atgaatttgc ggttttcggg taatcgcggt ctgacttgat
     8521 caggctgagg aaagtccatg ctcgcacagg ctgtgatgcc tgtagtgttc gtgcttagcg
     8581 aaaccataag ctaaggtact ctttggagta acggcaggaa aacaagctaa ggcttcggct
     8641 atgcttaagt atccttgaaa gtgccacagt gacgaagcgg ctggggaaac ccatccggtg
     8701 gaacgcggta aacccctcga gcgagcaacc caaacaatgg taggggcgct ttttgtctgg
     8761 aagaagaaca ggacaaaaag gcagtataac tgcagataga tggttaccgc tttgtttttt
     8821 ctccctggaa aagcaaagta cagaacatgg cttatagaaa accgcaaaca tcagggaatt
     8881 aggtcgtgac aaaagtaatg cgttataaga aacaagaaaa acatttgaaa gctatttttc
     8941 aatacttcag atgaatcgtt cttattacaa aacaaacttt tgtatcaccg gttattcgga
     9001 atttgagtaa aagtgtgggg taggactgat gtcccacctc ctttttttat aaataaggag
     9061 attgtgtatg gaaaaaaaca ggaagttcaa cctcgtcgca actgcggcaa gcgggctaga
     9121 agcactggtt ggtaaagaat taagagatct tggaatcgaa tgccaagttg agaacggacg
     9181 tgcacgtttt gaaggaacaa tggaaacgat cgctacagct aatttatggt tacgtacagc
     9241 agatcgagta aaaatcgtgg ttggggaatt cgatgcgtat acgtttgatg aattgtttga
     9301 aaacgtaaaa gcattgcctt gggaagattt tcttccacta gatgcagctt ttcctgtagc
     9361 tggaaaatcg atcaagtcga aactatatag cacacctgat tgccaagcga tcacaaaaaa
     9421 agcaatcgtt gaacgtctcc gtacctatta tcaccgtcca gcttctgtac cactgacgga
     9481 aactggcgca cattttcagt tggaagtagc tttgctgaaa gaccatgtga tggtaactct
     9541 ggatacgaca ggaccaagtt tattcaaacg tggttatcgc ttagaaaaag gtggagcacc
     9601 attgaaagaa aacatggcag cagcacttat tatgttgaca aattggcgaa aagaccgtcc
     9661 attttatgat cctgtatgtg gttcaggtac gctttgtatt gaagcagcct taataggcca
     9721 taatatcgca ccaggattca atcgtgagtt tgcttgcgaa tcttgggatt ggttcagtca
     9781 agaaatcatg gaaaatgttc gatcagcagc cgaagaaaaa gcagattatg atattgaatt
     9841 agatattact ggttcagata tcaatggacg gatgattgaa attgccaaag ccaatgcaga
     9901 agaaatcgga ttaggctctt cgattacctt taagcaacaa gcagtcaaag acttcaaaac
     9961 ggataaagaa tacggggtca tcgtggctaa tccgccttac ggagaacgtc taggagaaga
    10021 agaaactgtt cggaaattat ataaagaaat gggcgatgta ttccgtccat taaaaacatg
    10081 gagtaaatat atcttgacta gcgacttagc gtttgaggaa ttttacggac aaaaagcaac
    10141 caaaaaaaga aaattgtaca atggtgcatt gcgtacggat ctattccagt attggggaac
    10201 tcgtccgcct agaaaaaaag agaaagacga ataatcttac taattgattc attcaattgg
    10261 atgtttggag gaatagggaa tgaaagaaaa agagttttta caagaagtaa aagaaatcaa
    10321 tcttctacaa caagctttag gaatcctcga ttgggataca caaacaggta tgcctgaaaa
    10381 agctagtgca taccgaagtg aagtagacag ctatctttac agcatttatt tttcaaaaaa
    10441 aatcggtcca aaaatcaaag aagccattcg ctatttttct gaacatccgg aagaattgtc
    10501 ggaagttgga actgccgttt ttgccaaagt aaaagaagag tatgatttgg aacatcgcgt
    10561 accggaagat cttatgagaa aatatacagc tgccgtttct tcagcacacg gacaatggca
    10621 aaaagctaga gaaacacaac aattttctga ttttcaacac gcattgaatc aaaatattga
    10681 attaacaaaa cagttgatac cttactggag aaaagatgaa aagacgaatt atgatgtttt
    10741 gctgaatcaa tacgaacccg ggatgactgt cgaaatcctt gataaggtat ttgatcagct
    10801 taaagaagga attctttcga tccgccgtac gctccaagaa aaagggactg aacctgaaac
    10861 agacttttta aatcggagaa tgacgaaaaa acaacagaag agatttgtag tgaaagtaat
    10921 cgaacaactt ggttatgatt ttagtcgtgg tcgtttagat gacactgtcc acccatttat
    10981 gactggaatt aatccgaatg atgcacgaat cacgacacga tggaacgaaa cagatttcaa
    11041 aatggctgtt tttggagtga tccacgaggc tggtcatggt atgtatgaac aagacatcga
    11101 tgataaatat gcgtatacac cggtttatga aggtacatca atgggtatcc atgaatcaca
    11161 atcgttgttt aacgagatca ttattggaag tagtcgcagc ttctggaaaa agcaatatcc
    11221 tttctttcaa gaatgtgcag aaggaacatt cgatgatatt ccttttgaca aattttatcg
    11281 tttattgaac catacaaaat caagtttggt tcgtatcgag gcagacagtt tgacttaccc
    11341 tctccatatc atcattcgtt atgaaatcga aaaaatgatt ttcaatgaag gggtagatgt
    11401 tgctgaacta cctgaaatat ggaatcaaaa atatgaagag tatctgggaa tacgaccaac
    11461 aaatgatgtg gaaggcatcc tacaagacgt tcattggtca ggtgcaagct ttggttattt
    11521 tccctcttat gcattagggt acatgtatgc ggcacaatta cttcattctt tgcagcaaga
    11581 aatagatgtg gaaaatgttc tagcgtcaga cgattattct ccaatcaaaa actggatgtc
    11641 agagcatatc catcaatatg gtgcatctag aaaaccaaat caattaatca tggatgcaac
    11701 acatgaaccg cttaatccgc aatacctgat cgactatatg aaagacctgt attttaatgt
    11761 atatcaggta aaataaaata caatttacaa agatagctga aattcatcta atctatagat
    11821 gttttcagct atttacttaa gaaagaagtg gaacgaatgg ataaattaca agtgatcgct
    11881 gattatagta tggaccaatt agcgcatgat caaacaggac atgggagcga tcataccaaa
    11941 agagttgtca agttagctga aaaaattttg gagacggaac cgcaggcaga ccgctttgtg
    12001 acgcttgcag cagcttacct acatgatacg attgatgata aagtcgttaa aaatgagaac
    12061 gaggcaaagc aacagcttcg tgtattcctt cgctctttgc caatagtaga ggaacagatc
    12121 tcgatgattt tttccattat cgaaaatatg tccttttcta aaaatctctc tgaagcggcc
    12181 gaactatctc tggaaggtaa gatcgttcaa gacgctgatc gtatcgaagc attaggagca
    12241 atcggcattt tgcgtactgc ttatttcggc ggtggacatg ggcacccgat ttttgatcct
    12301 gaactgtatc cgcaaacatt caaggacaaa gaaaattacc gaaaaggcac gacagtgatc
    12361 aatcattttt atgaaaaact gttcttgctg tctgataaaa tgaatactga ttacggatat
    12421 gaagaagcca aacgaagaga aaccttcatg cgtgaattct tagaagaatt ttttctggaa
    12481 tggtctattg acgatgaaaa ttttactcca gacaattgga tcaaaaataa caaaaaatga
    12541 tggaggttgt gacagaagtg gtcagctcca agatatttcg gatcattttc cgtaaaagtt
    12601 acttctggaa cactgtttac caagaggtcg tgagcctgcc gttcagctcc gagtcacaag
    12661 gaacaatttc aaaaaatagc ttctcgtgtt tgatgaatat tgtaacttgt gattcggaat
    12721 tggcaggaga acaccgttta ttcggaagaa taggactgtg acaagacttt tgtcacagtc
    12781 cttttttcga attcaacaag taaaactttt aagaaatatt cagagagtaa aattaaaaat
    12841 tgctgataaa cgaagatgga aattttatgt atttttattg gtctatgcaa taaataaatt
    12901 aaatattcag aatacaattg attttaacga aagggcttct atcaatggtt gtgttgtatt
    12961 tatctgccca ggtagagtaa aatagatcat tatctaaaag gtaattgttc atactatata
    13021 agtcatttga aagtaaaaag atactgtaaa taaaaaatgt ggttaaataa ttctcataat
    13081 cagtgtaagc gttatcaaaa atatagcata cttgctttgt agatgaatga cacgatatat
    13141 gtttggtatg ttctgcaaga cagatgaata tggaggtgga gacaatgtct tccaaagaac
    13201 taacaatgta tttagagaaa gaattggatc aactgaaaga aaaggggtta tacaatacga
    13261 tcgacatact agaaagtgaa aatggtgctt gtatcatcgt agacggaaaa aagatgatca
    13321 atctagcatc caacaattat cttggatttg ccaatcgcga agaattgaaa aaagcatgta
    13381 ttgaagcaac cgaaacttat ggtgtaggag caggagcagt ccgaacgatc aatggttcgc
    13441 tgaaaatcca tcagcaatta gaagaaaaaa tcgcagaatt caaagggaca gaagcagcaa
    13501 tcgcctttca atctggattc aactgcaata tgggcgctat ctctgcagta atgacaaaag
    13561 aagatgctat cttatcggat gaattaaacc atgcatctat tattgacggt tgccgcttat
    13621 ccggagcaaa aatcatccga attaaacatc aagatatgaa agaccttgag aaaaaagcaa
    13681 aggaagcgat agaaagtaag aaatataaaa aaatcatgta tatcacagat ggtgttttct
    13741 ccatggatgg agacattgca cgattgccgg aaattattcc gattgttgaa aaatatggac
    13801 tgatcaccta cgtcgatgat gcgcacggct caggcgtaac tggaaaaggt gcaggaaccg
    13861 tcaagcattt tggattaagc gacaaaatcg atatgcaaat gggcacgtta tcgaaagcta
    13921 taggtgttgt tgggggttat gtagctggat cgaaaacact aatcgactgg ttgaaagcta
    13981 gaagtcggcc attcctattt tctacttcgc taactccagg tgcagctgca gctgcattgg
    14041 cttcgattac tttgatgcaa gaacatccgg aacttgtcga aaaagtttgg gaaaatgcta
    14101 attattttaa agaagaattg aaaaaagtag gctataacat cggtatgtct gaaacaccta
    14161 ttactccagt cattttggga gacgaaaaag tgactcagac tttctctaag aagctgatcg
    14221 aacatgggat ttatgctaaa ccaatcgttt atccaactgt gcctcttggg acaggcagga
    14281 tcagaaatat gccgactgcg gaacatacga gggaaatgct tgatgaagca gtagcagttt
    14341 atcaaaaaat aggaaaagaa atggaaatta tttaactaaa tttagttttt tcgtctattt
    14401 aaaattagag aacatgttca cgcatatatt gttaatcatc tgaagatagt agtaaaaaag
    14461 atcagggagg atcatcatga aaaaagtatt ggtgacagga tgtttaggac aaattggttc
    14521 agagttgatc acacggctac gtcaagaact aggcagtgaa aatgtcattg cgacagatat
    14581 acgcatgcct gaagtcattg agaaaaacga tatctttgag atcctagatg taatggatta
    14641 cgaaaaaatg cgcagcatag cagaacaata tcaagtggac acattgattc atttggctgc
    14701 tcttttgtca gctgttgcag aagcaaaacc acaattagcc tggaatttga acgtgactgg
    14761 gctggtcaat gcattggaag tcgctagaga attccagctg aaatttttta cgccaagttc
    14821 aatcggcgcg tttggtccaa atactccaaa agatcatacc ccacaagata ctcttcagcg
    14881 tcctacaacc atgtatgggg taacgaaggt agctggagaa ctactatgtg attattatta
    14941 tgtgaaatat ggcgtagata ctcgtggtgt ccgtttccct ggattgattt cttatgcaac
    15001 cttgccagga ggcggtacga cagactacgc agtcgatatt tattattcag caatcaaaga
    15061 aggaaagtac actagtttca ttgatcaagg tacatcaatg gatatgatgt atatgccaga
    15121 tgcgatcgat gccattataa aactcatgaa tgcagatcct gatcgattgg ttcatcgaaa
    15181 tgccttcaat atatcggcga tgtcttttga cccggaagag atcaaagcat ctattcaaaa
    15241 aatcatacca gattttgaaa tggattatga tgtggatcct gtacgtcagt caatagcaga
    15301 atcttggcca aattcactag atgtttcttg tgcgcaagag gaatggggct tttcgccgaa
    15361 atacgactta gatgtgatga caaaggatat gttggaaaaa ctgaaagaaa aattggtaga
    15421 gacggtataa aacaagaacc acatccaaaa agttttttat acttttggga ttggctatgg
    15481 tatgaaaggg gacaagggat ggaagaatat caagccacgc cagtaaaaga agtaaaaata
    15541 gaaaatgaat taaaacgtac gatgggattt tttactgctt tatcgactgt tatgggcaca
    15601 gtgatcggtg caggggtatt ttttaaagcc gcaagcgtag cagaagttac aggatccgcc
    15661 agtttgcata tgttttcttg gtttctcggt ggtatgattt ctgtctgtgc aggactaaca
    15721 ggagctgaac tggcagctgc tattccagaa acaggaggga tgattaaata tatcgaacgg
    15781 atttacggaa atacagcagc ttttttattg ggctgggcgc aagtcgtgat ttattttcca
    15841 gcaaatgtag cagccttgtc gatcattttc ggtacacagt tcgtcaatct atttggtctt
    15901 tcccagtcaa tgattgttcc cgtagctgtt acagctgctg tatcgatcct gttgatcaat
    15961 tttttaggtt ctaaagctgg aggggctttt cagtcgatta cgcttgtctg caagcttatt
    16021 cctttgtttg tgatcgtcat tttcggtttg ttccgacaag aaggagtaga cttccaactg
    16081 tttccgatcc aagcaggaga aaatctttca tttttctcag ccttgggagc gggcttgcta
    16141 gcaacgatgt tcgcatacga cggttggata cacgtaggaa atatttcggg agaattgaaa
    16201 aagccggcga aagatttgcc aaaagcaatt tctttaggaa tcatcggaat catgatcgtt
    16261 tatttattag taaatgcggt gttcttaaga accgcatcta tcgacggagt cgcaggaaac
    16321 agcaatgcgg caagtgacgt tgcaaaaatg atttttggcg gcttcggtgg aagactggtc
    16381 acagttggta tcttgatttc tgtttatgga accatcaatg gctataccct tactggaatg
    16441 cgtctccctt atgttatggc aaaagaaaac aacctgcctt ttagcaagct ctttgctaaa
    16501 cttcatgata aaactaaagt tcctgtagcc gcaggtatct tagagctagt catcgctatt
    16561 ggcatgatga tgatcggtgg ttttgataca ctaacggata tgctgatctt tgtcatttgg
    16621 attttttata cgatggtctt tgttggtgtc attcttcttc gtaaaaaaga acctgatttg
    16681 tttcgaccat acaaagttcc aatgtatccg tttattccac tagtagcaat cattggaggg
    16741 acttttatcg tatcaagcac gcttatcact cagacctttt tagcttcgat ggggatagta
    16801 ttgacacttg ctggtatccc gatttatctc tatttaaaac gtagatagct aaaacattcg
    16861 aattttatta gaactgcact tctctgccaa acaaaatatt ttatttaaat gaggagtacg
    16921 tggaagaaat gtcaaaagta ctcgttaatt ttgatcacgt aaatgtcgtt ttgtctacga
    16981 tgaaatagca aagtaaaaga cagaaatcgg gctcaaccga tttctgtctt ttactttgat
    17041 ttgcgtaact gaactattcg gcgtacgccg cgataaatat ttaataaaac caagcaacca
    17101 gaaatgaaaa tgggaagcca aatcagatag acagggtagc caagcacttt agacaaagca
    17161 tgtggagtca ttttatccat ttcaagaagt gcttgctgcc aagtctgaag attgaagact
    17221 agcatgaaac ccgaaataat caggagaata aatcctaaat aatgaattgt agttcttttt
    17281 cttacataag cgatcgtagc ataaaggaac agtaaaaaaa taggtacgcc aaaaacaaag
    17341 tacatattca gcatctcgac accccctttg tgtttatctt actttacttt gaaagaaatg
    17401 agaaataata gcctcgttac ttgcttgaaa cagcaaagga ctgctaagat aagagagata
    17461 caaagaatca aggaggagtc atatggcaag ttatatcgaa ccgattcgtt ttgcgctgat
    17521 tgtttttcca tttttagcct tagcgatctc atctgttttt tttatttatg aatatcgaaa
    17581 gtatggaaca tttctagtaa caagggcagt tattttgtat tctttcgttt tttatttatt
    17641 gtgtgcgtat tttttggtga tcttaccact tccggcaaag gagacggttg cccaaatgac
    17701 agggccaaag atggagctgc atttatttgc ttcatggcaa catttcagag acaacacggt
    17761 attggtcttg tctgaaccta gtacctacct gccggcaatg aagcagagtg tatttttgga
    17821 accagctttt aatgttttat tactcatacc atttggcatt tatttaagat attatttccg
    17881 gctttctttt atgaaaacga tgattgctag tttctgcctt tctctatttt ttgaattgac
    17941 gcagctaagt ggactttatt ttatctaccc aagaccatac cgcttatttg atgtgaatga
    18001 tttagtgaca aatacattgg gtggaatcat tggttttgtc gttacgccgt tatttacatt
    18061 tatgcttcct acaagaagac gaatggatga actttcttat gaaaaaggaa agactgtctc
    18121 attgactcga cgcttggtcg cttatttgat cgactggaca tttttatctc ttattaattt
    18181 ggtagcggcg attttcttta aaattgcgtt cgattcaggg gcagttactt ctcatatctg
    18241 gtggctttta ttagaagtag gggtatactt tatgattgta ccgtttataa ccaatggatg
    18301 gacacttggc aaaaaaattg tgcgtatccg tttggtggaa gaagaccgcg aacgaatttc
    18361 tttaaaagca ttgatgatcc gctacgggta tctgtacttt cttttttatg gtttaagctg
    18421 gttggggcag ttgcttcagc aaatcatgaa ttcgacaacg aatacggtgt tgcagatgag
    18481 tgcagtattc atttctctcg gtgtcttgtt actacaaggt atttttattt taaatatctt
    18541 gctatcattt ttgagaaaaa aacggattct gttttatgaa aaagctagtc acacatatac
    18601 tgttagcacg attggccaaa caaaggatga tgattctcga aattagctga gcaaaaacgc
    18661 tttgtctgtg ttataatgcc aaagtcgtga taatttaaag agaagaggtg cacgaatgaa
    18721 taattttgat atattccgct tcaaaccgtt tatcaatgaa gcgttaaccg caaagggctt
    18781 caaacagccc acagaggtcc aggaacgttt gattccttta attgcaaaag gaaaaaatat
    18841 cattgggcaa tctcaaactg gtacaggaaa aacacatacg tttttgttgc ctttgtttga
    18901 aaaaatcaat gcagaaaaag aggaagtaca agttgttatt acagctccaa gtagggaact
    18961 agctgcacag atctatgaag cagctacaca aatcgctaaa ttttctacac cggagatccg
    19021 tgtctcgaat tttgtcggcg gtacagacaa acagcgtcaa ttaaatcgtc tgcatcacca
    19081 acagccacag gttgtagtag gcacgcctgg tagaatatta gacatgatga atgaacaagc
    19141 gctgaagatt cacaccgcat ttgcatttgt tgtcgatgaa gcggatatga cattggatat
    19201 gggtttttta aatgaagtag accaaattgc aagtcgatta ccagaaaagc tgcagttttt
    19261 agttttttct gccactattc cagaaaaact tcgtccattc ttacgaaaat acatggaaaa
    19321 tccaatcatt gaagaaatca aaccaaaagc agttatttct gaagacattg aaaattggct
    19381 gatttcaaca aaaggtaaag atgagaatca aatgatttat caactgctga caattggtca
    19441 tccttattta gcaatcgtat ttgccaatac aaaacagcat gtggatgaaa ttgccgatta
    19501 cttgaaaaac caaggcttga aagtagcaaa gattcatgga gacatcaccc caagagagag
    19561 aaaacgagtg atgcgacaag tacagaatct ggagtatcaa tatgttgtag cgactgattt
    19621 agctgctaga gggatcgata tcgaaggtgt ctctcatgtt attaatgcag aaattccaga
    19681 agatctagac ttctttatcc atcgtgtcgg acgtactgga cgtaatggct taaaaggaac
    19741 ggccattacg ttatattcgc caaatgatga gcaagccatt gatgcgatag aaaaattggg
    19801 cgtctcattt gaaccaaaag aaatcaaaaa cggggaaatc gtcaaaacat acgatcgtaa
    19861 tagacgtgcc aaacgagaaa aatcaaaaga tgtattagat cccacgctga ttggtcttgt
    19921 gaagaagaaa aagaaaaaga tcaagcctgg ttataagaaa aaaatcgatt gggcaattgc
    19981 agaaaaaaat aaaaaagaac gcaaaatcga acgcagacag caaagccgta ctgctcgtaa
    20041 aaataagaaa aattcacata aataaaaaac aagaggttgt gacaaaaggc gtgtcacaat
    20101 ctcttgtttt taagctagac tttttttcat tccgatacaa agtacttcat cttcaataaa
    20161 aggttctgtg caagtatgat acccttgttt ttcataaaaa tctacagccg tcatttcagc
    20221 tactacataa ctagtctgac aaccttctga aaccgcccgt ttttcagcag cttcaagcaa
    20281 ctgaccgcct aacccttttc ctcggtattc ttttgctacg caaaatcgtt ccggcttgaa
    20341 gcaagtaggt gttttctttt cataacgcaa agtagctact ggtctttttt gatcaagaaa
    20401 tagataatag gtttgttgcg ggatatcttt tccgtcgaat tctagttctg caggaatccc
    20461 ttgttctaat acaaaaactt gatatctcaa aaagcagcta gctgcgcgta tccattcatc
    20521 cgctccaact atttttttca tcatattcct ccttgtcatg aatagcagag atgtattgat
    20581 tcctttattc ttatcgtacc aaaaatcgtg gagtatgacc aaaaggaaat gaaaataaaa
    20641 attgagatat tgacagtgat caatagaatg cgtatactaa ttaagtacga aaaggatatg
    20701 atttgttttt taagactcac agaaaattct ttcttggctg aaaaaagaat agtcactaat
    20761 caaattgctc cctttttcta ttttggtaga aataccgacg cagctcagcg ttatcgagtt
    20821 taagaggtaa tgattacaca tcattgcaat caaggtggta ccgcgagttt tcgtccttgg
    20881 ctgtgatggt gtttttttgt atttaattta tagaaagcag gtaatgacat gaaacaatta
    20941 agtagtgcac aagttcgaca aatgtttctt gatttcttcc aatctaaagg acatacgatt
    21001 gaacctagtg cgtctttgat ccccgtgaac gatccaacct tattgtggat caactctggt
    21061 gttgcaacat tgaaaaaata ttttgatggt tcagttgtgc cagaaaatcc aagaatcaca
    21121 aatgcccaaa aatctattcg aacaaatgat atcgaaaatg tcggtaaaac agcacggcac
    21181 catacgatgt ttgagatgct gggtaatttt tcgattggtg actatttcaa aaatgaagcc
    21241 atccactggg catgggaatt tttgactgat ccaaaatgga tggcattcga tccagaaaaa
    21301 ctttatgtaa cagtttatcc aaaagataca gaagcaaaac gcatctggca tgaagaagtt
    21361 ggcctgccac tagatcacat tattgatgta gaagacaact tctgggatat cggtgcaggc
    21421 ccatgtggtc cggatacgga aattttctat gaccgtggag aagcttataa cgatttagca
    21481 gaagacgatc ctgaaaacta tccaggagga gaaaatgaac gttatttaga aatctggaac
    21541 ttagtatttt cagaattcaa ccataagcct gataacacat ttgaaccact tcctcataaa
    21601 aacattgata cggggatggg attggaacgc atggtctcaa tcgttcaaga tgcgtcaacg
    21661 aactttgaga cagacttgtt tatgcctatt atccacgccg tagaaaagct aagcaaacaa
    21721 gtaaaatatg gtgaaaaccc agtaacagat atttcttaca aagtaatcgc agatcatatt
    21781 cgcgcccttt catttgctat tggcgacggt gcattgccat caaatgaagg gagagggtat
    21841 gtcttacgcc gtttgcttcg tcgtgctgtc atgcatggga aaaaattagg tattgaacaa
    21901 gcattcttat atcgtttagt ccctgttgtt ggggaaatca tggtaagtta ttatcctgaa
    21961 gtacttcaac aaaaagaatt tattgaaaaa gttatccgta cagaagaaga acgtttcaat
    22021 gaaacaatca atgaaggttt ggaaatctta aatcaagtga tccaagaagt aaaaaacgaa
    22081 aacgggacga ctctagcagg aaaagacatc ttcaaactat acgacacata tggcttcccg
    22141 gtagaattaa cggaagaggt ggcagaagat gaaggactga aagttgatca tgctggtttt
    22201 gaaaaagaaa tggatgcaca acgcgaacgt gctcgctctg cccgcagtac tgaaaaatca
    22261 atgggggtac aatctgcttt attgacagat atcaaagtag aaagtaaatt cattggatac
    22321 acagaacaag aatcagatag tcaattattg gtcatcgtta aaggtgagtc tcttttgaat
    22381 gaagtcgcag aaggtgaagc tcaaatgatc tttgatcaaa cacctttcta tgcagaaatg
    22441 ggtgggcaag tagcggatca aggatggatc atgaatgaag taggcgaaat cgtagcagtt
    22501 gttacagatg ttcaaaaagc gcctaatggt caatttatgc acaccgtaga agtaaaagca
    22561 ccaatgagtg aaggacaaac ctatcatcta ttgatcgatc aatcgatgcg caatcggatc
    22621 atcaaaaacc atacagcaac ccatctactg cacaaggcat tgaaagaagt acttggcgag
    22681 catgcaaatc aagctggttc tttagtcgct cctggacatt tacgattcga ctttacccac
    22741 tttggtcaaa tcacttcaga tgaattagct gaaatggaaa gaatcgtcaa cgaaaaaatc
    22801 tgggaagcta tcccagttga aacaattgaa acagatatcg atacagccaa aaacatgggt
    22861 gcaatggctt tgtttggtga aaaatacgga catgacgttc gagtagtaaa tattggcggc
    22921 tggtcaatcg aactgtgcgg aggcacacat gtagcaaata cagaaaacat cggaatcttc
    22981 aaaatcgttt ctgaatcagg aattggtgca ggcgtgcgac gaatcgaggc tgtaacaagt
    23041 aaagaagcgt acgaactact tgaagaagaa gaaaaacaac taaaacaagt agcaacaatt
    23101 gttaaatcac ctcaattgaa agaagttgtt tcaaaagcgg aacaattgca acagcaagta
    23161 agagagctac aaaaggaaaa tgaacaatta gctagcaagt tagcgaatca acaagctggt
    23221 gatgtattca aagatccaga aacgatcaat ggaaaaacaa tcattgcagc acaagtaaaa
    23281 gtgaaagata tgaatcagct gcgtcaatta gctgaccaat ggaaacaaaa aaatatttca
    23341 gatattcttg ttttagcaaa cgaacaagaa ggaaaagtca gtctgctagc ggcaatgacg
    23401 aaagaatcaa atgaagctgg actaaaagct ggcgacttga ttaaagcaat cgcaccgaaa
    23461 gtaggcggtg gcggtggtgg acgtccagac atggcacaag ctggcgggaa aaatcctgct
    23521 ggtattccag atgcacttaa agctgcgaaa gaatgggttg cgcaacaata gggcgtttac
    23581 gtttgacaga aaaacaaaag ttcaaacatt gaacgaaaca tgattatggg ggcgaagaca
    23641 aacaagtctt gccctcatac ttttttcaat tggatggcgc atctaatcaa atggtcggat
    23701 tcggatggtc tttagttgac gaaagtgaca gaaattttta cgattagtat aaataaaaag
    23761 gggtgaaaaa atgaatagta gaaataagac ctttcgacta gtcttacgtg cgatcttgtt
    23821 agcaatcatc atcgtacaag cgatggttcc ttggctgggg tttattccat taggattcat
    23881 tagtttaaca attatccata tcacagtaat tattgctgca gtagtattag gcccaaaaga
    23941 tggcatggtg attggcttgt tttggggaat cgttacaatt gttcgtgcct atgccatgcc
    24001 aacaacgcca tttgatacat tagtgttcac gaatccgatt atctcggtag ttcccagagt
    24061 acttgttggc ttagtagcag gcttggtttt ccactggatt tatcaaaaaa ataaatcaat
    24121 aacgatcagc tcagcctttg caggggtact gggttcattg gtcaatacag tcttagtgtt
    24181 aggattcatg ggattatttt atacaggtgc aacggcagat gcctatggtg tagactctgc
    24241 tcttttattt aaaaccttag caggggttgc agcaatcaat gggataccag aagcaatagg
    24301 tgcgggaatc ataacaccat tactagcaaa agcgttattt gcagcaacac cgttgaaacc
    24361 agaataatga ccatctttta atagtaatag gacgcacgat agatagaaaa aggaagagag
    24421 gagaggaaaa caatcgtcct ctccatcttt ttacctgagc aacaagcaaa ctagaagggg
    24481 taaaaaactt ggctaagaaa caagaagaaa aaaagaaaca aataccgcaa cagcggacaa
    24541 aaaaaggagt actagcgggt atcttaggat tggttacgaa tctgatcttg tttgtctcta
    24601 agctaatgat cgggcttttt tcaggaagtg tctccattat ggctgatgca gtgaacagtc
    24661 tatcagatac tgcttcatcc atattgactt tgatcggatt taaaattgct gcaaagccag
    24721 cagatcagga acatccttat ggacacgaac gcttcgaata tatcagtggg ttatttgttt
    24781 cgatcatcat tacttatgta ggatttcaat ttttagagtc ttctgctgaa aaaatcatcc
    24841 atccagaaaa tgtctcttta acacccatcg tcttttttgt cctaatcatt tccatctttt
    24901 tgaaatttgc acaaggcaaa atgtatcagg ttattgcgca atccattgat tctgaaacat
    24961 tgagagctac agcaacagat agttataatg atgtctttac tacactggct gtattgcttt
    25021 cagcagcaat cgaatgggta actggatggc gtattgatgg atatataggt tttgctttag
    25081 cattatatat cctttatagt ggattgacga tgcttcgaaa ttttgtatac gaactattag
    25141 gaagtcgccc aacgccagca gagattgaag aaatggaaga gcatttaaat gcttgcgatg
    25201 atatacttgg ctatcatgat ttattggtgc ataactatgg acccaataaa cgctttgcat
    25261 cagtccacat cgaagtagat gaatcaatga atttgaatgt ggctcataag attattgatc
    25321 tgatagaaaa agactttaaa aagtctttgg atgtggaact tgtctgtcac ttggatccaa
    25381 tgcctgttga taacgaaaaa tactataata tcttgcggca gttaaagcaa attcttcttg
    25441 aaacaggtac agggcttaat attcatgatt ttagagtaat tcatcaagga aaaacgctgc
    25501 aatttgatgt agtggtccct gagaaattcc agtttgttga tacagaacta gaaagaatct
    25561 tacgtagtca aatagaagaa aaaatcggag attaccaatt ggaaattacg tttgatcaca
    25621 attatctttt atattaaatg agaaactata aaaagactcc ttaaagtttt taatttaaag
    25681 agtctttttt tcttttaatt gtttatggag agcctgacgt gcaagattat ctgctccttt
    25741 atttttgttt tcgggcaacc attgcaggat caataaagaa aattcggata gaagttcttg
    25801 gattctttga aggtagggaa ggaagagctc gttcttcgtt gcgtttttgt cgaccgtaga
    25861 aactagtgtt ttgctgtctg aaaaacagaa aatcgtttca ttctgtaagt cgtttttctt
    25921 tagaaattct aaagttttta aaaagacttc gaactctgct tgatggtttg tccctataga
    25981 aagcgggata gatagctgtt cttgtttacc ttgatagaca atcaagattc cacctccact
    26041 aggaccaggg ttgccttttg tagaggcatc aatgtatact tttaacataa aaagagattc
    26101 tcctttttgt tcaaactaat gttatggtaa gattatatca ttactgaatc ggtgagaggt
    26161 tagagaatga aaaaaaatat tcgatggcag cctgaactgg cacatacgat catctattgg
    26221 tcattgacct tgatcattct gttttttagt ctgattcttt ctttagaaaa cacaggtcct
    26281 tattggaaaa gcaattttgt tttaggtatt tttcttgttt ttctatttct aggtttgcgg
    26341 cgttctttta ttttaaaatc aaactctgtg attatacgtt atgctgcttt ttggaaagac
    26401 cgagaaatat ctgtcggaca gattcgatct ttgacgccaa ctaatactgg ggtgcaaatg
    26461 atgttgcaag atgagaaagc cccatctgtt ttcatgatgc gaaaaaaaga tcaagtagtc
    26521 ctttttgatc attttgaaaa aaacggaccc aaatcagaat caattcctta tccttatacg
    26581 aaaaaaagaa aaagctaatt ttaaaaatca gaacctaaaa aaacgaattt ttacaggaaa
    26641 agaaaagagt gagacgtacg gttcatcccg tttagcgtct cactctattt gtttatctat
    26701 tcatgcatac tagtatcggt agtctgaacg ttgcctttct tgacatgggc agcttgtgtt
    26761 cctcgattcc cttcgatgat ctcaaattcg accacttgat tttcttccaa agttttgaat
    26821 ccctcttctt caatcgcagt aaaatgtaca aaaatttctt ctgtgtcatc ataactgata
    26881 aagccgtatc cttttttgtt gtcaaaccat tttacaattc ctgtggtcaa agcactcacg
    26941 acctttctaa agtctgatca tagccttcat tataaagagt atttataagt acgtcaaata
    27001 aattaaaaac ctgtaatttt atgttttttt tctgaataaa aaaaggtata attggcatat
    27061 cttaacaaag aagatatttt gttgaataaa gttcgtgaaa aggggtaatc aaatgaagaa
    27121 tgatctgcaa atttcacaag aaacagagct agaaccgatt gttgaagtgg ctagtaaatt
    27181 agatcttaag gaagacgatt tggaactgta tgggaaatat aaggcgaaaa tcaatttttc
    27241 tggaatcaat cgatcaaagg ataacgctga ggggcatttg atcttagtta cttccatcaa
    27301 tccaacacca gctggcgaag gaaagtcaac gatcactgta gggttaggag acgcgctcaa
    27361 taaaatcaat aaaaaatctg ttattgcatt gcgagaaccc tcacttggtc ctgtgatggg
    27421 aatcaaaggt ggtgctgcag gcggaggata tgcacaggta ttgcctatgg aagatatcaa
    27481 cttgcatttt actggtgaca tgcatgctat cacaacagct aataatgcat tatctgctct
    27541 tttagataat catattcatc aaggaaatga attgaacatc gatgcccgcc gagtgatttg
    27601 gaaacgggta gtcgatctca atgatcgtga actgcgtaaa gtaattgttg gcttgggtgg
    27661 gccaatccaa ggtgttccaa gagaagatgg gtttgatatc acagttgcca gcgaaatcat
    27721 ggctatcttg tgtcttgcgg cagaccttga agatttaaag gctcgtcttg caaggatcgt
    27781 tgtcggctat acatttgacc gtcagcctgt gactgctgga gacttgaaag cagaaggcgc
    27841 tctggcatta ctgctgaaag atgcaatcaa gccgaatctt gtacaaacaa tttacggaac
    27901 accagctttt gtccacgggg gaccgtttgc caatatcgct catggctgca atagtatttt
    27961 agctaccaag acagcattga gattagcaga ttacgttgtc acagaggcag gatttggtgc
    28021 agatcttggc ggagagaaat ttttagatat caaagtacct aacttgaaaa aagcgccgga
    28081 tgctgtggtg attgtcgcca ctgtccgtgc attgaaaatg catggcggaa tgaaaaaaga
    28141 tgaacttaaa aatgagaatc ttgatgcttt gaaagtaggt tttgcaaatt taaagcgcca
    28201 tatacgtaat atggaacaat atcagctacc tgtgatcgtc gcaatcaatg aattcgtaac
    28261 agatacagac aatgaactca cactgttgga gcacttgtgt gaaaatcagg ggattcttgc
    28321 caagagagcg agtgtatggg cagatggagc agaaggcggc gttgatttag caaaagctgt
    28381 agtacgattg attgatagaa aagaagctaa ttacaagcca ttataccgcc tagaagaaac
    28441 gatacaagaa aagacagaaa caatcgtcaa gaaaatttac ggaggaaatg gtgttgtttt
    28501 cagcaaaaaa gcgcaaaaac aaatagaaga gtttacgaag aatggatggg acaaactgcc
    28561 gatttgtatg gcaaaaacac agtattcatt ttctgatgat ccttcactgc taggtgcacc
    28621 ggaagatttc accatcacga tccgcgaaat catcccaaaa ttaggggcag gatttttagt
    28681 agccttgact ggagatgtta tgacgatgcc tggtttgcct aaaaaacctg ctgcattgaa
    28741 tatggacgtg acaaatgacg gagaagtgtt gggattgttt taagcttgat tataatctac
    28801 catcgaagga gctgtatttt gactacagct tcttttttta gacgataggg aattaatttt
    28861 gtttacacta ggatcattct ttttctttat tgtattttga gctatactaa agcataatag
    28921 gagggtatga tgaaaacgac atttataaga aaaaccggtt tttacggtat gggtagctcg
    28981 attcagctaa gaatcaacaa tgaaaaacgc agtgttctca gtcatgaaca aaagataacg
    29041 cttgatctgg aagtgccctt tacgatgcag gtcacctttt attggctaaa aagccccgtt
    29101 tatacagtga aagaagcaaa gcctgcttat gtgatcacaa tgaattactt gattcttcaa
    29161 atctatccgt ttttatttct agcaactggg ttgggggccg ttttcctaca aaatttattt
    29221 ttcagttttt ttgcagttat tgtgttgatt gcgttctttt tctatataaa aaaccgggca
    29281 tatttgatca aggaggaaaa ttatggcaaa ctctgatctt tttttaatca gtttcaatcg
    29341 aatcgaaaaa tggatgagag acgagatggg aaatgcacga aatatgggat ttaccgaact
    29401 tgtcagacgc ctagctcaaa gaaaacaatt aatgatcaga aaatacgaag atgatctttt
    29461 acagcttgct cagttaagga atgcgatcgt ccatgatcgg atcgcagtcg attttgtcat
    29521 tgcagagcca aatgattgga cagtcaagcg aatccagctg atcgaacaag aactgattca
    29581 gcctgaaacc gtgctgcctc gatttgcaaa acgtgtaaca ggttttgaac aagatcttcc
    29641 gttacttgaa ctgttaaaga tagtagcaga aaaaaggtat tcacaatttc cgttatacaa
    29701 taaaggaaaa tttgtagcat tgattacttt acgtaatatc gggttttggc tagcaaaaga
    29761 aagccaaaaa ggtccggttg atttaacaaa taaacgagcg ttggatttga tcatccaaaa
    29821 cggaaagtac acaaattatc attttgttcc agctaaaaca catatttacg aggttgaagc
    29881 gatgtttcgt gagcaaggga ctttggaagc cgtacttatc actaaagatg ggaatcccga
    29941 tggtaatctg ctcgggatcg tacgacctcg tgatatttat aaacaaatag aaaaggattg
    30001 attttttgtt aattatttat tggatattca gcgctttgct agtaggagtg gatcagttgg
    30061 tcaaatggtg gatcactgat aatctagcgc ttggagagac gaaaaatctt ataccaggta
    30121 ttttgtcact gaatcatatt cgaaacactg gagccgcatg gagtatgcta gaagggaaga
    30181 tgtggttctt tactatagtg acactcattg cagtcgttgt gattctcaca ttgatgatta
    30241 aaaatcgtga aaaaggtaat cgctggttca tgattggatt gagtttgatt ctagctggtg
    30301 cgattggcaa ttttatcgac cgtattcgtc ttggctatgt agtagatatg ttccagacag
    30361 attttatgag ctttccgatt tttaacgtag cagatgtgac acttgtatgt ggagtgattt
    30421 gtatgttaat ttatattatt ttagatgaaa aggatcaaag aaaaaaatga cagaacttaa
    30481 aacgacgatt caccatgaat ctggtaggat cgataaagta ttgactaatt tattcaccga
    30541 ttacagtcgt tcgcaaattc agctgtggct gaaaaatgga gcggtttctg tcaatggaca
    30601 gccagtcaaa gcaaattaca aagtaaaaca aggagacgag attactgtct tgatccccga
    30661 accagaaaca ttagatgtgg tcccagaaaa tatcccgttg acgatcgttt acgaagatga
    30721 agatgtagcg gtgataaaca aacctcaagg aatggtcgtt catccttcag caggtcatac
    30781 gcatggcaca atggtcaatg cgctgatgta ccatatcaag gatctttcta cgatcaacgg
    30841 cgttattcgt ccaggtattg ttcaccgaat cgacaaagat acttccggac tgctaatggt
    30901 tgccaaaaat gaccaggcac acgaatcatt agctcagcaa ttaaaagata agacctcttt
    30961 gcgcaaatat gttgctttag tccatggaga gattcctcac gaaaaaggaa ccatcaatgc
    31021 gccaatcggc cgttcgaagg aaaaccggaa aatgcaggcg ataagagaag atgggaagtc
    31081 ggctgtcaca cattttactg tattggaacg tttcgaagga tttactctgg ttgaattaaa
    31141 actagaaacc ggaagaacac accagatccg tgtgcatatg aagtatatcg gttatccgtt
    31201 agctggagat ccagtatacg gaccgaagaa aactttgaaa ggcaatggtc agtttctcca
    31261 tgcgcaaatg ttaggtttta cgcacccgac tacaaacgaa aagatgatct ttgaagcacc
    31321 tcttccagaa gtttttgaaa aaactttaga aaaattaaga aaaaacattg cattttaatt
    31381 tagataacgg tatagtaatt aacaacgaaa gcataaaact taatagaatt cctttaagtt
    31441 tagtcccgtg aggctaagaa gggtgggagc aaggatacgt atggtgcgcc ataagtagat
    31501 tgctcattga catagtatag ctatcagtgt atcagtatac gctcagtcta aacattcctc
    31561 ctgtcctctt agggcaggag tttttttatg caaaaaagta gggggaatga aaatgcaagc
    31621 aaaagaagta gtagatcagg taaccatgaa gcgagcattg actcgaatta cttatgagat
    31681 tatcgagaga aaccatagta tccaagatat cgtattggta ggtatcaaaa cacgaggaat
    31741 ctacattgca tcaagaattg ccgaacgcct gaagcagcta gaagatatcg atattcctgt
    31801 aggagaactg gatatcactt tataccgaga tgacaaaaaa gaaaatccag aagaaccgga
    31861 acttcattct tctgacatcc cagtttcctt agaaggaaaa gaagttattt tgattgatga
    31921 tgttttgtat acaggacgaa cgattcgagc agcaatggac gcagtaatgg attttggcag
    31981 accaagaaaa atttcattag cagtcctggt cgatcgtggg catcgagaat tgccaatccg
    32041 tgcagattat gttgggaaga acattccaac atctcgggcg gaagagattt tagtagagat
    32101 gcaagagctt gatggacaag atcgcatcat gattttgaaa gaggaagatt agaggagaga
    32161 gaaacatgtc ggagaaaaaa ggatttcata atgatgacgt ggtgttagat atccacgatc
    32221 gcccaacccc aggacattgg gtaggattaa gtttacaaca cttgttcacg atgttcggag
    32281 caaccgtgtt agtccccatc ttagtaggta tcgatccagg tattgcgcta gtcagttcag
    32341 gactaggtac attggtgtac ttatttacta ctaaaggaaa gatacctgcg tacttaggaa
    32401 gcagcttcgc tttcattgca gcgatgcagc ttttgatgaa aacagatggt tatccagcga
    32461 ttgcacaagg agcagtcaca actggattag tctatttgat tgttgcgctg atcatcaaaa
    32521 agatcggttc agcatggctg gataaaatct tgcctccaat cgtcgtcggt ccagtcatca
    32581 tggttatcgg gttgggactt gcggcaaatg cagcaacaaa tgctatgtat aatcagggca
    32641 cgtatgattt caagtatatt gctgtagcgc tgatcacatt aggattaaca attttcttca
    32701 acatgtggct aagaggtttt ctcggattga ttccgatttt actaggtatt attagcggat
    32761 acatcgtagc cttgctgttt ggaatcgtgg atactaagcc aatcgtagac gctgcctggt
    32821 ttgctgttcc taactttgag attccctttg tacaatatga accaaagcta tatcttggag
    32881 caatcacaac aatggcaccc atcgcttttg tgacgatgac agagcatatc ggccatctta
    32941 tggtattgaa taaactaact aaacgtaatt tctttgaaga accgggtctt cataagacgt
    33001 tgacaggtga tggattagca caaatcgtgg cagcctttgt cggaggtcct cctgtaacaa
    33061 gttacggtga aaacattggt gttctggcta tcacacgtgt ccatagcgtg tttgtgatcg
    33121 gtggagctgc agtatttgca gtcattttag gattcgtagg aaaattaagc gctttgattt
    33181 taagtatccc tggaccagtc atctcaggaa tcagttttat cttatttgga gtaattgccg
    33241 caagtggaat gaagatttta atcgagaaca aaatcgattt tgataaaaag aaaaatctgt
    33301 tgattgcttc agttatctta gtagtaggaa ttggcggact cgtctttgaa gtaggcacat
    33361 ttacattgtc ggcaatggca ttagcaactg tacttggcat cattttaaat cttatcttac
    33421 cagaaacttc acgaagcgaa gaaaactaag gaggaaacat tatgatcatc aaatcagaac
    33481 gtatcagctt aaagcattta ttgaccgttg aggcacttac tgatcaagaa gttatgggct
    33541 tgatccgcag agggcaggaa ttcaagcaag gtgctaattg gactccgcaa aagcgccagt
    33601 actttgctac aaacctcttt ttcgaaaata gtactcgcac acataaaagc ttcgatgtag
    33661 cggagaaaaa actagggcta gaagtgattg aatttgaagc aagcacaagc tctgtccaaa
    33721 aaggggaaac actatacgat acagtactga cgatgtcagc attaggcgta gacgtagcgg
    33781 ttatccgtca tggtgatgag aactattatg acgaactgat acaaagtaaa acaatccagt
    33841 gttcgattat caatggagga gacggaagcg gacagcatcc aacccaatgc ttgcttgatt
    33901 tgatgaccat ttatgaagaa tttggtcatt ttgaaggtct gaaagttgcc atcgtaggtg
    33961 atatcactca ctctcgcgta gctaaatcca atatgcagat gttaaaacgt ctaggcgcac
    34021 aagtattctt ctcaggtcct agagaatggt acgacgatga attcgaagtg tacggacatt
    34081 atatgccatt ggatgaacta ctagatcaag ttgatgtcat gatgatgctt cgggtgcaac
    34141 acgaacgcca tgatggaaaa gaaagtttct caaaagaagg ctaccatcag gaacatgggt
    34201 taacagttga gcgtgcgaag aagttgcaaa aacatgcaat cattatgcac ccagcaccag
    34261 ttaaccgtga tgtagaatta gctgattcat tagtggaagg attacagtcg cggatcgttc
    34321 agcaaatgag caatggagta ttcgtcagaa tggcaatctt agaagcagtg ctaaatggaa
    34381 aagcgtaatt ataggaggat gaaaaaatga aaacactcat taaaaacggt cagatcaata
    34441 cacgaaaaaa tatgacgaca ccagcagaaa tttggataga agatgggcga atcaaagcaa
    34501 tcggtacagg attctcagaa gccgaatttg atgaagtgtt tgatgcaaag ggacaattga
    34561 tcacacctgg tttagtggac gtccatgttc atttgagaga gccaggattt acatacaagg
    34621 agacgatcga agctgggact cgctcagctg ctcgtggcgg tttcactact gtatgcgcga
    34681 tgccgaattt aaatcctgta cctgatacgg cagaaaagct gagacaagta tatgacatca
    34741 ttagaaaaga tgcagttgtg aaggtattgc agtatgcgcc aatcacagaa aatctgcgaa
    34801 gtgagaaatt agttgatcaa gaagcactga ttgaagaagg tgcttttgct ttcacaaatg
    34861 acggtgtagg tgtccaaaca gctgggacga tgtatctggc tatgaaagaa gctgcaaaaa
    34921 acaataaagc cctagtagcc catacagaag atgaatcttt attatttggc ggcgttatgc
    34981 acgctggcaa gaaggcagaa gaacttggtc ttcccgggat cttaagcgta accgagtctt
    35041 ctcaaattgc tagagatctg ttgctagctg aagcaactgg tgttcattac catgtttgcc
    35101 atgtttctac taaagaaagt gtccgtgtaa tcagagacgc aaaaaaagca ggaatccacg
    35161 taacagcaga agtttcaccc catcatctta ttttgatcga cgaagatatt cccgaagatt
    35221 tcggcttttg gaaaatgaac ccgccgctaa gaggacggga ggacagagaa gctttgatcg
    35281 aaggcttgct tgacggtacg atcgattgca tcgctacaga ccatgccccc catggattag
    35341 aagaaaaaag ccaaagtttc atgaaatcac catttggtat cgtaggaagc gaaacagcgt
    35401 ttcaactgat ctatactcat tttgtagaaa ctggtcgatt cacgttggaa caagtgatca
    35461 attggttggc agttaaaccg gctgagattt ttggtttgaa tgcaggaacg ctaacggttg
    35521 gtgcccccgc tgatgtagca gtttttgata ttacacaaac ttgcacgatc gataaagaag
    35581 actttttatc aaaaggggag aatacacctt ttatcggctg gaaagtaaaa ggcgaaacac
    35641 aaatgacttt tgtcaacgga aaacttgtgt ggcagaaggg agaataaaag tatggaacgt
    35701 ttgcttatat tagaagatgg aacagttttc gaaggaaagg cttttggtgc agatgctagt
    35761 gtcttcggag aaatcgtttt tacaacaagt atgactggtt atcaagaaac tatcactgat
    35821 caaagtttta acggtcaaat cattacattt acctatccta tggtgggtaa ttatggggta
    35881 aatagagatg attatgaatc gatttctcca acatgcaaag gagtagtagt aaaagaacat
    35941 gcacgtgtag cttcaaactg gcgaaaccaa atgacgctag attcattttt gaaacaaaaa
    36001 ggaattcctg gaatatcagg tatcgatacg cgcgccctta ctcgcaaaat ccgtgaagtc
    36061 ggaacgatga aagctagtat agttgatgct ggagattcct tcgaacatgc atttgatcag
    36121 ctgaaagcaa ccgttctagc aaccaatcaa gtgcagcaag tctcaactaa caaaccttat
    36181 ccaagtccag gaacaggtcg gaaagtcatt gtcattgact tcggcttgaa acatagtatt
    36241 ttacgagaat tgagtaaaag aaactgtaac ctcacagtac ttccctataa cacagatgcc
    36301 gagacgattt tagcgctatc accagacgga gtcatgctga cgaatggacc tggtgatcca
    36361 aaagatgtgc cagaagcaat cgaaatgatc aaaaaaatcc aaggaaaagt accgattttt
    36421 ggtatttgtc tcggtcacca gttatttgct ttagccaacg gtgcagatac ctataaaatg
    36481 aaattcggac atcgaggatt aaatcacccg gtacgagaag tagcgaccgg aagaattgat
    36541 tttacttctc aaaatcatgg ctatgcagtc gatgaagcca cgattgatcc agaaaaactc
    36601 atcgtaactc atgtagaagt aaatgacgga acagtagaag gagtcaaaca cagagattat
    36661 cccgctttca gtgtgcagtt tcatccagat gctgcccctg gtccgcatga tgcactacat
    36721 ttatttgatg aatttatgga aatgatggac gcaggaaagg agcagtaaac agatgccgaa
    36781 acgtacagat atcaagaaaa ttatggtgat tggatctggt ccgatcatca ttggtcaagc
    36841 cgcagaattt gactacgcag gaacacaagc ctgccttgcc ttaaaagaag aaggatatga
    36901 agtggtttta gtaaattcta atcctgcgac gatcatgacg gataaagaag tggcagatca
    36961 agtatatatc gaaccgatca cacttgaatt tgtatcaagg attcttcgaa aagagcgtcc
    37021 agatgctctc cttccaactt taggcggaca gacaggcctc aatatggcaa tggagctggc
    37081 agcatcaggt attttagaag aattgaacat agaacttcta ggaacaaagc tttctgcgat
    37141 cgatcaagca gaagatcgtg atctattcaa acagttgatg aaagaattga atcagccaat
    37201 ccccgagtct gaaatcgtca atacagtaga agaagctgta gattttgcaa ataaaatcgg
    37261 ctatcctgtc atcgttcgtc cagcctttac tttaggcgga actggtggag gtatgtgtga
    37321 aaatgaagaa gaattacgta tcgtatcaga aaatggatta agtctttccc ccgctaccca
    37381 atgtttgatt gaacgaagta ttgcaggttt taaagaaatt gaatatgaag tgatgagaga
    37441 ttcggctgat aatgcaatcg ttgtctgcaa tatggaaaat tttgacccgg tgggtatcca
    37501 tacaggtgat tctatcgtat ttgcccctag tcaaacattg tctgaccatg aatatcaaat
    37561 gcttcgtgat gcttctcttt cgattattcg agcacttaag atcgagggag gctgtaatgt
    37621 ccaactcgct cttgatccac atagttttaa ttattatgtg attgaagtca atccgcgtgt
    37681 ttctcgttca tctgcgttag caagtaaggc gactggctat ccgatcgcta agctagctgc
    37741 taaaatagcg cttggattaa cattagacga aatgaaaaat cctgttacag gaacgacttt
    37801 tgcagaattt gaacctgcat tagattatgt tgtagctaaa attcctcgct ggccgtttga
    37861 taagtttgaa aacggagaac ggcttttagg cacgcagatg aaagcaactg gtgaagtgat
    37921 ggctatcggt cggaatatcg aagagtcttt attgaaagct gtgcgttctt tagaaatcgg
    37981 tacacaccat atcgaacttc ctgagttggc agacatcacg gacgatgacc taatccaaaa
    38041 agtggttcga gcacaagatg atcgcctgtt ttatgtagct gaagctatta gaagagggta
    38101 caccatagaa gaattagcgg atttgacaaa aatcgattta ttctttttag ataaactgtt
    38161 gcatatcgta gaaatcgaac agcagttgaa acagcagccg ttggatgaca agatattgaa
    38221 aacagcgaaa caaaacggtt ttacagacaa aaaagtggcg gagctgtggg aaataaacga
    38281 agaagccgtt cgccagatga gaaaagaaaa tgatttgatt cctgtatata agatggttga
    38341 cacttgtgca gcggaattcg aatcaaaaac accttatttt tatagttcct atgaatatga
    38401 aaatgaaagt tcacgatcag aaaagccctc aattctagta ctgggatctg gtcctatccg
    38461 tatcggacaa ggggttgaat ttgactatgc gactgtgcat tctgtcaaag caatccagca
    38521 ggcaggatac gaagcaatca tcatgaacag caatcctgaa acagtttcga ctgacttttc
    38581 tatttcggat aaattatatt ttgagccatt gaccttcgaa gatgtgatga atgtgatcga
    38641 gctagaacag ccgataggag taatcgttca atttggtggt cagacagcaa tcaacttagc
    38701 cgaacctttg actgctgctg gtgtaaaaat cttagggaca acgatcgaag acttggatcg
    38761 tgcggaaaat cgtgatttat tcgagcaagc gctgaaagag ttggatattc ctcaaccttt
    38821 aggggatact gctacaagta aagaagaagc cgtggttatc gcttcgagaa ttggttatcc
    38881 agttcttgtt cgtccaagct atgtattagg cggacgtgcg atggaaatcg ttgaaaacca
    38941 gcgagattta gaagattaca tggaacatgc tgtgaaagca tctccagaac atccagtact
    39001 agtggaccgt tacttgcttg gtggtgaatg cgaagtggat gcgatttgtg acggtgaaac
    39061 agtactcatc ccagggatca tggagcatat tgagcgtgct ggtgtccatt caggggattc
    39121 aatggctgtg tatccacctc aaacattatc tgaatcgatc aagaaaacga tcgaagatta
    39181 cacgatccgc ttagcattag gtttgaattg tgtcgggatg atgaatatcc agtttgtcat
    39241 ccatgaaaat gaggtttatg tgatcgaagt caatcctcga gcaagtcgga ctgttccatt
    39301 cttaagtaag gtgacaggaa ttccaatggc acaaattgcg acgaaagcta ttttgggaga
    39361 gaaactaaag acacttggtt atgaaaacgg actttatcca gaaacaaaag aagttcatgt
    39421 taaagcacct gtcttttctt ttacgaaatt gcagaaagtt gatacttact tagggcctga
    39481 aatgaaatcg actggagaag taatgggatc tgacagacaa ttagacaaag ctttgtacaa
    39541 ggcattcgaa gcttctggat tacacttgcc tgaatatgga gccgtattat ttacgattgc
    39601 ggacgaaaca aaagaagaag cactagaatt agctaaacgt tttacagaaa ttggctatag
    39661 tctgatagga acgaaacata cagctgctta tttcgaaaaa aatggtctgg tcgttgaaac
    39721 agtagcgaaa atttctgagg aagcagcaga aaaaaatgta gtcgacttaa taagagatgg
    39781 taaaacacaa gtggttgtca atacgattga taaagatcgg ggaaatgctt ctaaagacgg
    39841 tttcatcatc cgaagagaag cagttgaaca tggtattcca ttgtttactt ctttagacac
    39901 agcagatgcg atcgttcgag tgatggaatc ccgtgctttt tcaactaacc ctatttaacg
    39961 gcgagcacat gttaagacaa aaagacgaaa aaccgttgca ggaggggaca gatgaaacaa
    40021 gaaatgatgg aaatcgttca gcaaaaacag ctggcaccaa agatttttga aatgacattg
    40081 aaaggtgatc tagtaaaaga aatgcagcaa ccaggacagt tcttgcatat tctcgtgccg
    40141 cgtgcagact tgctattacg ccgaccgatt agcttgaatc atatcgacca cgaaacaaat
    40201 acttgccgta tcatttatcg ggtggaaggt gaggggacta gagtcttctc tactctttct
    40261 gccggagacc atttagatgt catgggtcct ttaggcaatg gttttgattt gtccaatctt
    40321 catacaggag acgaagtatt tataatcggt ggaggaatcg gtgtccctcc tctatatgag
    40381 ttatcaaaac agttagtcga aaaaggaatt aagccaacgc attttttagg ttttgccaca
    40441 catgaagtcg tttattatga aaaagaattt aatcgtctag gagaaacaag aatcgctact
    40501 gacgatggaa catacggtat gcacggaaat gtcggtaatt tattgttagg aacgaagacg
    40561 gaacctacag ctgtttttgc atgtggttca aacgggttat tgaagacagt ggaacagctg
    40621 ttttcttcgc atcaaaatgt ccagttatca ttagaatccc gcatggcatg tgggataggg
    40681 gcttgctatg cttgcgtttg tcatacgccg gaagatgaaa caggaacaaa aagtgtgaaa
    40741 gtttgtgacg aaggaccgat ttttaaaata ggagaggtaa ttatatgaat gagaatcctt
    40801 tagcggtcaa acttcctggc ctagaattaa aaaatcctat catgccggca agcggctgtt
    40861 tcggttttgg caaagaatac ggaaaatact atgatttgaa tcagcttgga tcgatcatgg
    40921 tcaaggcaac gactccaaat gcccgctttg gcaatcccac gccaagagtg gcggaaacac
    40981 catctggcat gttgaatgca attggtttgc aaaatcctgg tctagacgtt gttatgcata
    41041 aacttcttcc agaattagag gagtacaatg agttacccat catcgcaaat gttgctggtg
    41101 cttgtgaaga agactatgta gaagtttgta gcaaaattgg cgaagcacca aatgtgaaag
    41161 caatcgagct gaacatttct tgcccaaatg tcaaacatgg cggaattgct tttggaacag
    41221 attctgatgt tgcttttcaa ttaacacaag cagtaaagaa agtttcttct gttcctgtct
    41281 atgtcaaatt gtccccaaat gtaacagaca tcgttccaat cgctcaggca atcgaagctg
    41341 gaggggcaga tgggtttacg atgatcaata ctcttcttgg tatgcggatt gaccttaaga
    41401 caagaaaacc gattttagcc aatcaaacag gtggactctc cggaccagca atcaagcctg
    41461 tcgctattcg tttgattcac caagtagcaa gtatatccag ccttccaatc attgggatgg
    41521 gcggcgtgca gacagtggat gatgttcttg agatgtttat ggctggagca agtgctgtag
    41581 ctatagggac cgcgaatttc accgatccgt atatctgtcc taaactaatt aaagagctcc
    41641 ctgtgcgaat gagcgaacta ggcatcgaat cgctggaaag attaatcaaa gaagtgagag
    41701 aggaacgtga acgatgaatc aactagacca acgaccaatt attgcattag atttttcaac
    41761 taggcaagag gtagaagact ttcttcgatt tttcccgaaa gaagaaaaat tgtttgtgaa
    41821 aatcggaatg gaattgttct accaagaagg acctgaaatc gtacgttatc taaaagaggc
    41881 tggtcataat gtatttttag atctgaaact tcacgatatt ccgaatacgg tcgaaaaagc
    41941 aatgcgggga ttggcaaagc ttggtgttga tctcacctgt gttcatgccg ctggcggtat
    42001 tcgtatgatg gaggcggcaa tgcgaggatt agaagagggg actccagaag gtggaaaacg
    42061 tccgctactt ctagctatca ctcagcttac ttctacaagt gaagaagaaa tgcatgccga
    42121 tcaactaatc gaagtttctt tagaaaaaag tgtgatccat tatgctagct gtgccaaaaa
    42181 agcaggatta gatggtgtgg tttcttctgc ttgggaagta gaagcgatca aagaaatggc
    42241 aggagacgaa tttgtttgct taactccggg tataagacca gaaggaacag tcgcaggaga
    42301 tcagacaaga gtagtcacac cttctcaggc aaaaaagatc ggctcaactt ttatcgttat
    42361 aggtcgacca atcactcagt caactaatcc ttataaagca tatcaaacga ttcaaacaga
    42421 atggagctaa cctaaaatga atgttgaaca aagtatcgca aaagacttat tagaaattga
    42481 agcagtattt ttaaatccaa gtaatccttt tacatgggca agtggaatca aaagcccaat
    42541 ttactgtgat aaccgaatca cgatgagcta tccaaaagtc cgaaaagaga tcgcaaaagg
    42601 attagcaagc aaaatcaaag aagcttaccc tgaagtacaa gtgattgctg gaactgcaac
    42661 agcaggaatc cctcatgccg catgggtagc ggaaatactg gatttgccaa tggtctatat
    42721 tcgaagtaag gcgaaagatc atgggaaagg taaccaaatc gaaggacgta tatttgaagg
    42781 tcagaagatg gttgtgatcg aggatttgat ttctacaggc ggaagtgtct tggaagcagc
    42841 tgaagcagca aaaagagaag gtgcggatat ccttggtgtt gcggctatct ttacgtatga
    42901 gttgccaaaa ggaaaagcaa atttcgaaaa agccgaaatc cctcttatga cgttgaccaa
    42961 ttattctgta ttgattgaag cagctttaga agatcgttat atcgatgagc aagaattaac
    43021 tctgctaaaa gaatggaaaa aagatcctga aaattggcag atttaagcgc gcttgatgaa
    43081 gatagagaaa tccgatttgt gtctccagaa tcatcaattg gaatagcaaa aatccaaaaa
    43141 ctgattgcga gaagcatctt ttcatcaggt atgaaaagaa acttctatcg tgatcagttt
    43201 ttgatttttt taaaattcat ttttctaaga ctggttagca gaaagaagag aataatctct
    43261 tctctttttt ctattatata tagattttct ctattttttg gtaagggagc tgtttcaaaa
    43321 atggtaaaga gcggaaatgt tgcgaatatc agttatttaa tgatatgata ttcggaaaaa
    43381 gaaatctcaa agggaggtaa cttttatggg gttgaatgaa tttattttag gattgaacaa
    43441 tttagagacg atcacaaggg cacctggatt ttttaaatat acagagcata cagttgcagc
    43501 acattcgtat cgtgtagcat ctattgcgca agttctagga gacattgaag aagcgaatgg
    43561 acaaccgatc gattggaaac tgctctatga aaaatcattg aatcatgact acacagagcg
    43621 ttttattggt gatatcaaaa cgccggtgaa atacgcaagc aaagagttaa gagggatgct
    43681 gcaaacagtt gaagaaaaga tgacggacga attcatcaac caagagattc cagctgagtt
    43741 ccaagaagtt tatcgccgtc ggttgttcga aggaaaagat gaaaccgtag aaggagaact
    43801 attagccatt tcagataagg ttgaccttct ttatgaatct tttgatgaaa tcatcaaaaa
    43861 taacccggaa aaagtttata aggagatgtt cattgaggca gtgactacga ttaaaagctt
    43921 tgaacatcgg ccttctgttc agtatttctt taaagagata tttccggaac tattgaacca
    43981 ggaattttat ggaaaagagg cgtttttaga aaccgtctca acgattgtaa agaaagaaga
    44041 aaaataaaaa tgatatgaga tgcaggggga agtatagttg aaaaagaata tggatgtcga
    44101 atggggctat tctggagaca aaggtccgga aaattgggcg agtttatgtg attggtttgc
    44161 gagaggtgcg gaatttccat tgcagtcgcc tattcatttg accaaggggg aagaaaccaa
    44221 aatagaagga gacacgcttt cctttcatta tcaaaagcaa cggtttactg acaaggaatt
    44281 caaaaacacg attcatttag taccttttga ccaactcagt tatgtagagt tcaagaaaga
    44341 acgctattat ttgacagata ttcatttcca cttgccttct gaacatatca tcaacggaaa
    44401 acaggaagat attgaatttc attttgttca tatgaacagc aaaaaagaga atctagttgt
    44461 gggtgtcatg taccagctaa tggtacagga aggttggctg tataatcaag aaaatgggga
    44521 aagttggaac ttagaaaaac atgagcattg ggtaaatccg gatgtgttct ttccggagca
    44581 aaaaagccat ttccattata ttggctcatt gacaactccg cctaccagcg ggccaatcca
    44641 atggtttgta atggatcatg taggaaaact gaaccaagag tttcttctcc ccttcgatgg
    44701 tcagtatgct cgaccgaaca accgaccaat ccagcccttg aatggaagag aaatttatta
    44761 tttcgaggag tttgagcaat gaatattcag cagatgaaat acgtggtcgc tgtagcaaac
    44821 aatggtagtt tcagagaagc ggcaaagaaa atgtttgtct cccagccaag tctttcagct
    44881 ggtatcaaag aattagaaac cgagttaggg atcacgctgt ttactcgaac gaatcgaggg
    44941 gcatatttaa cagaagaagg gcaagacttc ttaaatcgtg ccgagaaaat attggtccag
    45001 cttgatacat tagaaactca ctatctaacg agtgaaaaga gagacaattt ttcgatcgct
    45061 gcccagcatt atgatttctt aggtcctttg accgcacagc tactcgagga attcaaagac
    45121 gagatcaaac aatttcggat catggagacg acaacagcga gagtgatcga agaagtcaaa
    45181 gagcagcaca gtgagatcgg cattatttat atgaatgagc ataatcaagc tggtatcaga
    45241 agatatttac aacaaggaga gctaagtggc cgcagcattg gaaaattcaa aacgcatatt
    45301 tttttaaggc aaggacatcc attagctgaa cacgcagaga tcaccaaaga agaattgtta
    45361 tcttatcctc aagttcgttt tacacaggat ggaaataatt tcccgtattt ttatgaagac
    45421 cttatcgaga tccctgatca agaaacagtg atttatacga gtgatcgagg tactttgatg
    45481 aatatcgttc ttgaaactga tgcttacgct tcaggatctg gtattgtgat tggagggatt
    45541 cgcgagcact tgcggttaat ccctttggca gaaggcgaac taaatgaatt ttatatcatt
    45601 tattcggcga aacgtccgct cagtgaaatc gctcaaagat ttatcaaaga gcttactcgg
    45661 ttactggacc agcagagcta agaaaagcag atgagaacgc tgtttattga acaccgttga
    45721 tcaaaaaaga ggggttgtga cagaattttg tcacaactcc tctttttgta gcaaacaatt
    45781 tataactaat tgctgttgtg ggaaagtacg caaatatgat tctagaaaca ctcattgatt
    45841 acctgttttg tttcatagct gtaatttttt cttcttctgg tgtcacgata atcgtctttt
    45901 ggttttcata aataacataa ccaggcttgg cgccatttgg ttttcggata tgctttacct
    45961 gtacaagatc aaccggcact tgggcagagt atcggtattt tgaaaaatag gcagctaact
    46021 cggcagcttc tgtaattgtt tcatctgagg gcttgtcact tttaatgatg acgtgcgaac
    46081 cgggtatatt ttttgcatga agccaatagt cggttttttt agctgtcttc attgtcagct
    46141 ggtcattttg aagattgttt ttaccaacaa gaatgagcgt tccgtcagaa gaaaagtatt
    46201 gatcaggctg agatggtttc ttacgttttt gtttttttaa gttcttcttt ttcaggtatc
    46261 cttctgaagt caattcttct ttaattgctt cgatatccat tgggccggca atttccagtt
    46321 gagataagac agattcaaga tattggattt catctttggc ttcttggatt tgttcgccaa
    46381 tcagcttaac agcgttcttc agcttttggt atcgatggaa atatttctgt gcattttgat
    46441 ttggtgtcaa tgccggatct agtgctattt tgattggccg atcttcttca taataattag
    46501 gtaaaacaac ttcttttgcg ccgcgtggta cttgtgtcag aaaagtagta agtagttcgc
    46561 catttctacg gtaattctca gcgttttcgg attctttgag tgtttgttca cgttttttca
    46621 atttattttt atttcgtttt agttcatttt cgatttttcg aatcagttct ccgccttgtt
    46681 gttttgcccg atctttctct gctttttcgt gataatagct atctaataat tgactgagtg
    46741 ttggataagc tgttacagca gatgcctgtt cggacaatac ctgataagca atcggtgtga
    46801 aaaaatcttt attttccgtt tcgtaaaaag taggaatagg ctgatggctg atggctgaga
    46861 aaaattcgtc ccatacaacc atcttttcat taggacgttc cagtaatctt ttggtcagct
    46921 cttgagcgat atcgaaaccg attccctgaa actgacgttg gattgctttt ggatctagtt
    46981 cagtttggga aagccgctga aagatttttt ctttctcgga gctaaatggg ttcaagacct
    47041 cttgttttgg cggagcaaca tattctacac caggaagcaa agaacgataa gtgttttgag
    47101 agcttccaat gtgtttgatc gcatccagta tttttccagt ttctcgatta actaagacga
    47161 tcgtactatg acgtcccatt aattcaacga tcaatatgat attttgtaga tcacccaact
    47221 cgtttcgttt agcaaagtgg aaatggatca ctcgatcatt ttcgatttgt tcgatgtctt
    47281 ctaaaatagc gccatccaaa tattttcgaa gcatcatcac gaagttaggc ggattatcag
    47341 gattctgata atcgatttgg gtaatctgta cacgagcata acttgggtgc gcagataata
    47401 ataatcgatg gtttttgccg cgtgaacgaa tcaccagcac gatttcattt tcataaggct
    47461 gatggatttt cgagatccgg ccagatagta acgtttcacg caattcgttg accatcgcgt
    47521 gggtaaatac accatcaaag gacatggttc attcctcatt tcttttcata agtatattca
    47581 ttataacgaa aaaaagaaga aaaaccaatt tggccgaata gtaaagcaaa agtctagaaa
    47641 aatcttggac taattacata aaaaacagtg tttctatcgt tgaaatccaa atttttaggt
//
LOCUS       DAYNVV010000015        43451 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.015, whole genome shotgun sequence.
ACCESSION   DAYNVV010000015 DAYNVV010000000
VERSION     DAYNVV010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43451
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.015"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(98..1228)
                     /locus_tag="ACGXWR_001002"
     CDS             complement(98..1228)
                     /locus_tag="ACGXWR_001002"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HFK0802602.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKE
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1288..1515)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1877..3079)
                     /locus_tag="ACGXWR_001003"
     CDS             complement(1877..3079)
                     /locus_tag="ACGXWR_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFK0802603.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3139..3342)
                     /locus_tag="ACGXWR_001004"
     CDS             complement(3139..3342)
                     /locus_tag="ACGXWR_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFK0802604.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3484..4551)
                     /locus_tag="ACGXWR_001005"
     CDS             complement(3484..4551)
                     /locus_tag="ACGXWR_001005"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFK0802605.1"
                     /translation="MLDSLQEEVVPVNRVLIDYLTIHFFSNQHLKLIEEIIEMPIERF
                     EELDYAPKGYIGQYVWNQVITIRYSIDDAVKGTVMEFSGQGCKHLARWLKTRKTNWQQ
                     FFRKVLDYQGNFTRIDFTLDDFVGSLSIPELKHKVILGHVWTTFQVSESHGGTDIINN
                     ESNGETLYLGSKKSQCRFCFYQKDHEQRKRRGIPLEEAKVKNRFELRYRKEKAQSLAK
                     IISKTHDLTKLFFELLNGAICFYDRDPNDLGAKVDAKWAAFISNYGAITISLDTIPQS
                     FEKTMSWLIHGVSPSLVFIAQVDQTFHSSLLPLIIEQGEMNPRQIKLLQNMKADPEYY
                     QEEVEYYERKLQSISNEKTSY"
     gene            complement(4609..4716)
                     /locus_tag="ACGXWR_001006"
     CDS             complement(4609..4716)
                     /locus_tag="ACGXWR_001006"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0802606.1"
                     /translation="MNQVNQHDLGEAIRVSREERGWTQRYLAEKVGISR"
     gene            4879..5691
                     /locus_tag="ACGXWR_001007"
     CDS             4879..5691
                     /locus_tag="ACGXWR_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0802607.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6065..6256)
                     /locus_tag="ACGXWR_001008"
     CDS             complement(6065..6256)
                     /locus_tag="ACGXWR_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802608.1"
                     /translation="MKQKFFIAIIATKKFHRGKRFGQKWKFPPKVTAPQLKSIKELEF
                     ENALVICMTCTDEVFRKHF"
     gene            complement(6501..6730)
                     /locus_tag="ACGXWR_001009"
                     /pseudo
     CDS             complement(6501..6730)
                     /locus_tag="ACGXWR_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6714..6911)
                     /locus_tag="ACGXWR_001010"
     CDS             complement(6714..6911)
                     /locus_tag="ACGXWR_001010"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFK0802609.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            complement(7057..7935)
                     /locus_tag="ACGXWR_001011"
     CDS             complement(7057..7935)
                     /locus_tag="ACGXWR_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFK0802610.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMLSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7974..9092)
                     /locus_tag="ACGXWR_001012"
     CDS             complement(7974..9092)
                     /locus_tag="ACGXWR_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HFK0802611.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9089..11188)
                     /locus_tag="ACGXWR_001013"
     CDS             complement(9089..11188)
                     /locus_tag="ACGXWR_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HFK0802612.1"
                     /translation="MTINEVIYSPKHPLFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLGNLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPLYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETMNYFAQLFGQLSMSDDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACSGLAEIFEALEQLSLSERYKDIACKLKESICKQMTIDGTF
                     GEQFLEGIGDEEKTTYSVKNYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDPLYQNTMTFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSDMHNH
                     QAFVTRLEELICLADLDGSWWWWPYRLEAKQGEVVRDFGCGKCGWASGLFVSIMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIYIQRRKR"
     gene            complement(11239..12060)
                     /locus_tag="ACGXWR_001014"
     CDS             complement(11239..12060)
                     /locus_tag="ACGXWR_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFK0802613.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLGCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12057..12866)
                     /locus_tag="ACGXWR_001015"
     CDS             complement(12057..12866)
                     /locus_tag="ACGXWR_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFK0802614.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFVMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12887..13381)
                     /locus_tag="ACGXWR_001016"
     CDS             complement(12887..13381)
                     /locus_tag="ACGXWR_001016"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFK0802615.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13393..13893)
                     /locus_tag="ACGXWR_001017"
     CDS             complement(13393..13893)
                     /locus_tag="ACGXWR_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFK0802616.1"
                     /translation="MIKPMFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLS
                     SIQLLTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITK
                     TFLEKEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVN
                     EEEDFF"
     gene            complement(13958..16654)
                     /locus_tag="ACGXWR_001018"
     CDS             complement(13958..16654)
                     /locus_tag="ACGXWR_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFK0802617.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17082..18155)
                     /locus_tag="ACGXWR_001019"
     CDS             complement(17082..18155)
                     /locus_tag="ACGXWR_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFK0802618.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18152..18979)
                     /locus_tag="ACGXWR_001020"
     CDS             complement(18152..18979)
                     /locus_tag="ACGXWR_001020"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0802619.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18980..19786)
                     /locus_tag="ACGXWR_001021"
     CDS             complement(18980..19786)
                     /locus_tag="ACGXWR_001021"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0802620.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19798..20883)
                     /locus_tag="ACGXWR_001022"
     CDS             complement(19798..20883)
                     /locus_tag="ACGXWR_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802621.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20900..21442)
                     /locus_tag="ACGXWR_001023"
     CDS             complement(20900..21442)
                     /locus_tag="ACGXWR_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFK0802622.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21700..22689
                     /locus_tag="ACGXWR_001024"
     CDS             21700..22689
                     /locus_tag="ACGXWR_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HFK0802623.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22686..23423
                     /locus_tag="ACGXWR_001025"
     CDS             22686..23423
                     /locus_tag="ACGXWR_001025"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HFK0802624.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23420..23971
                     /gene="coaC"
                     /locus_tag="ACGXWR_001026"
     CDS             23420..23971
                     /gene="coaC"
                     /locus_tag="ACGXWR_001026"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HFK0802625.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23987..24619
                     /locus_tag="ACGXWR_001027"
     CDS             23987..24619
                     /locus_tag="ACGXWR_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFK0802626.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24704..25351
                     /locus_tag="ACGXWR_001028"
     CDS             24704..25351
                     /locus_tag="ACGXWR_001028"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding oxidoreductase"
                     /protein_id="HFK0802627.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25356..26339
                     /locus_tag="ACGXWR_001029"
     CDS             25356..26339
                     /locus_tag="ACGXWR_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HFK0802628.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(26742..28256)
                     /locus_tag="ACGXWR_001030"
     CDS             complement(26742..28256)
                     /locus_tag="ACGXWR_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HFK0802629.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28394..29200
                     /locus_tag="ACGXWR_001031"
     CDS             28394..29200
                     /locus_tag="ACGXWR_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802630.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29375..29944)
                     /locus_tag="ACGXWR_001032"
     CDS             complement(29375..29944)
                     /locus_tag="ACGXWR_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFK0802631.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30027..32087)
                     /locus_tag="ACGXWR_001033"
     CDS             complement(30027..32087)
                     /locus_tag="ACGXWR_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HFK0802632.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(32364..33842)
                     /locus_tag="ACGXWR_001034"
     CDS             complement(32364..33842)
                     /locus_tag="ACGXWR_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0802633.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(34140..35075)
                     /gene="murB"
                     /locus_tag="ACGXWR_001035"
     CDS             complement(34140..35075)
                     /gene="murB"
                     /locus_tag="ACGXWR_001035"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HFK0802634.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(35148..36068)
                     /locus_tag="ACGXWR_001036"
     CDS             complement(35148..36068)
                     /locus_tag="ACGXWR_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFK0802635.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            36181..36933
                     /locus_tag="ACGXWR_001037"
     CDS             36181..36933
                     /locus_tag="ACGXWR_001037"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFK0802636.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            37919..38452
                     /locus_tag="ACGXWR_001038"
     CDS             37919..38452
                     /locus_tag="ACGXWR_001038"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HFK0802637.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(38942..39466)
                     /locus_tag="ACGXWR_001039"
     CDS             complement(38942..39466)
                     /locus_tag="ACGXWR_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFK0802638.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(39459..39932)
                     /gene="tsaE"
                     /locus_tag="ACGXWR_001040"
     CDS             complement(39459..39932)
                     /gene="tsaE"
                     /locus_tag="ACGXWR_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HFK0802639.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(40055..41035)
                     /gene="pta"
                     /locus_tag="ACGXWR_001041"
     CDS             complement(40055..41035)
                     /gene="pta"
                     /locus_tag="ACGXWR_001041"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HFK0802640.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(41188..41868)
                     /locus_tag="ACGXWR_001042"
     CDS             complement(41188..41868)
                     /locus_tag="ACGXWR_001042"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFK0802641.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            41994..42863
                     /locus_tag="ACGXWR_001043"
     CDS             41994..42863
                     /locus_tag="ACGXWR_001043"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFK0802642.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            42889..43404
                     /locus_tag="ACGXWR_001044"
     CDS             42889..43404
                     /locus_tag="ACGXWR_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HFK0802643.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
BASE COUNT        12954 a         8990 c         7439 g        14068 t
ORIGIN      
        1 aataaataat ataaaaggta aataaaaaag agtggatttc tccactccat gaaaagccga
       61 ctttttggga cgcttttttt tgccaagcct cacattttta tagccaaact tcttttgcga
      121 cttgctgcaa taattggatt ttcttccatt gttcttcttc tgttaaatgg tttccttctt
      181 ctgttgaagc aaacccacat tgaggactga tacttagatt ttccaatggt acaaattgtt
      241 gtgcttcttt tattcgttct tttattttct ccgtatcttc caaatctgga aacttagaag
      301 taactaatcc taaaacaact ttactttctt tgttactcca atgtcttaaa ggagtaaaat
      361 ctcctgctcg gtcagaatcg tattccaaaa agaaaccatc ataatttgtt gaaaacaact
      421 cttctgcaat gggttcatat ccaccggaaa acagccaaga agaagcgtga ttcccgcggc
      481 agatatgtgt tgtgatcgtc aaatcttctg gtttgtcttc cagtgcgtta ttgataatct
      541 ctgtacaaat atgggccatt tctttcggat caatttcttt ttgaagaagt gcttctcttt
      601 tagtttgatc agctagaaac gcccaatttg tatcatcgaa ttgcaggtaa cggcaacctt
      661 tttcataaaa agcatgaatc gctgctttgt aagtagagga caagtcctca taaaaatcag
      721 atagatcagg ataaatctcc ttgatttttg aagaaccatc attagatagg atctcttgtc
      781 gtaaaatcat cgtgggacta gggatcgttg cttttgcaac aaaagtatca tctgtttcca
      841 ctacttcttt cagaaaagca aaatctttta aaaatgggtg atttggattg aaagataatt
      901 tatctactac ccgaatatta taagctggtg ctgcttttcc gtggaatgtt tgattatatc
      961 cagtttctgg aacatagcct tcgataccat ttagttcttc taaaaaatca agatgccaaa
     1021 atccacgccg aaattcacca tctgtaattc ctttgatgcc gactgctttt tggtcttcca
     1081 ctaatttttt tatttcctgg tcttcgattg cacgaagttc ttcttttgaa agtaagcctt
     1141 cttgaacttt ttttcttgct tctttgatcg attgcgggcg taagaaactt ccgacatgat
     1201 ctactgtaaa tggtctattt ttgctcattt cattcactct tttctttgtt ttttgtaaaa
     1261 aaaaatcctt ttactagcaa atactagtaa aaggacgatt atactcgtgg taccaccttt
     1321 tttcagaaaa aacattcttt ctctcagcct gacaataaaa tcagtggtct tggtaacgaa
     1381 agactgttcg tttttgccta cctttcgaca aaaaatcctc taaggccatt ttcgacagtc
     1441 aacttctagc tttttacacc aaccaaagcc tctcttgaac cattttctgt ctactttcct
     1501 tctcatcgga tactattaga ataaaattag aatagcatgt ttgaaagaaa agtcaatagg
     1561 gaataagaac aaacaaaaac taatttgtta ttcttagtaa tttgtttgtg gaatacaata
     1621 aagcttttct aatatgataa ttgttcagtc gtcctttcat cttagatcac ttccttaaaa
     1681 tgatcatacc cgtttcaacc acataaaaaa ggacttaatt ttgaaaaatt tcccatcaaa
     1741 actaagtcct ttttattata gttatgcaaa tttgcttatt ttctcgctat ttccgataca
     1801 tcttgaacag gtgcaattcg actgaaaaca ctggtgcaaa agcatttatt tgtcttatgg
     1861 tagaaccgtg gaaaactcag actggtaata aattgtcatt ttttgaaaga atagcgccct
     1921 cttgaacatt atcaatcgca cttaccactt gttgatctga ctttgcatat aagtgaccgt
     1981 aagttcctaa agtgatttga atattcgcat ggcccaatcg ttcttgaata gatagcggtt
     2041 gaatattctg ctcaattaga aatgcaacat gagaatgtcg tagcgcgtga agcttaatcg
     2101 gtttgacacc cgctttttta gcagcttctt ttaaccagtt cgcaaaagaa taaggtggcg
     2161 taaatgttcc gtccaactga gcaacatatt caaaatttcc aatacgtttt tgcaagtcat
     2221 accactgtct gagttttaag gaaagcttct tccccaaccc aatcgttcga taagcacatt
     2281 tagttttggg agtcgaaaag taccaatcat cttttgtatt ataaatcaat gtcttctcaa
     2341 tcgttatcgt gtttttctca aaatctacat tcgaccaaga caaagcttca agttctccaa
     2401 tccgaatgcc agtataaaag agcatttcat acacaatctt ccgatggtgg gtttgaatct
     2461 tatcatcctt caattcattc atcacttttt gaaactcact gtgttcccaa aactcaactt
     2521 tcttattctc agaaggaagc gaagaaacat cttcaacggg atttttagca atcaccccct
     2581 ctttaacagc ccgatccaat acaattttta ggtgccctcg aatccgattg atataagatt
     2641 ttgataacgt ttcgccatta acttttttcc gtgaattacg tgactctgtc tggcttagtt
     2701 caaataacca atcctcaata tcgtgacttg taatatctcg aacacgaaaa tgatagaaaa
     2761 actgcatacg cttttcgaaa atgaattgcg cattctcata tgtttgactt ttgacctgtc
     2821 tctcgtacca ttttacaaac ctatccttgt aaaactcttc gaaagtcatt tgattggtag
     2881 aacacagttg attaggaatt gtcttgttaa aatcatgtgt ttccatgtac ttgtcataag
     2941 caattttggc atctttttgt gaagcataac ctcgtttagt cttctgaacc tttcttccat
     3001 tttcatctat acctagatac gctcggaaga accatttttt tgtcttttta tcttggtaaa
     3061 tatttttaat ttttggcatc gttccattcc tccctgtact tgagaaaagc tactttaata
     3121 gtaccgcgct tgtactgttt attccgcaac ttgaatgtga aaaagatgtt caattactcg
     3181 ggatggcacc acaccaactt ggcgattatt ataaaaatca ataccttcaa tccttgcaag
     3241 atatgccttg ctctctttaa tcattcgtgc agcttgacta ggtttaaagc ccatctctat
     3301 caaaattgca cgatttacca tgaaatcaca ttttgtttcc attctctcac ctcctgattc
     3361 tttactcctt ttaaaataat cctctttata atctattgtt tctcattcga tggttgtgtt
     3421 atactcgtct tgtcgaggcg gagtacgttg cacaacttgt tgtgtaagca gtactttgct
     3481 tttttagtag cttgttttct catttgatat actttgtaat tttcgttcat aatactcaac
     3541 ctcctcctga taatactccg ggtctgcctt catattttgg agaagtttga tctgtcttgg
     3601 attcatttct ccttgttcaa taatcaaagg caacaaggaa gaatgaaacg tttgatcgac
     3661 ctgtgcaata aaaactaatg atggtgaaac accatgaatt aaccaactca tagttttctc
     3721 aaaactttga ggaattgtat ctaaagaaat ggtgattgcg ccataattgc taataaaggc
     3781 tgcccatttg gcatcaactt ttgcacctag atcatttgga tcacggtcat aaaaacaaat
     3841 tgctccatta agtaactcaa agaacagttt ggttaaatca tgggtttttg aaataatctt
     3901 tgccaagctt tgcgctttct cttttcgata ccgtagttca aagcgattct ttacttttgc
     3961 ctcttctaaa ggaattcctc gtcgcttccg ttgttcatgg tccttctgat aaaagcaaaa
     4021 acgacactga ctcttctttg agcctaaata caaggtctca ccatttgatt cattgtttat
     4081 gatatccgta ccgccatgag attcactcac ttgaaaagtg gtccacacat ggcctagtat
     4141 taccttatgc ttaagttctg gaatgctgag actccccaca aaatcatcta aagtaaaatc
     4201 aatccgtgta aagttcccct gataatctaa taccttacga aaaaactgtt gccaatttgt
     4261 ttttcgtgtt tttagccatc ttgctaagtg tttacagcct tgacctgaaa actccatcac
     4321 agttccttta accgcatcgt caatggaata ccgaatcgtg attacttgat tccacacgta
     4381 ttggccaata tagccctttg gcgcataatc cagttcctca aaacgttcaa tgggcatttc
     4441 aataatctct tcaattagct ttaaatgttg attcgagaaa aagtgaatgg ttagataatc
     4501 aatcaaaaca cggttaactg gaacgacctc ttcttgcaaa ctatccaaca caagattcaa
     4561 tttttcttca cttaattgtc tcgttccttt ttctactttc gataataact atctcgaaat
     4621 ccccactttt tctgctaaat atcgttgtgt ccaccccctt tcttctcgag aaactcgaat
     4681 ggcttcaccg agatcatgtt gattaacttg gttcatagac aaacctcctt ctgctattta
     4741 cttgtcaaag aacctattga acttatttta agtacatttt tattgtacgc ctgtatttat
     4801 tttaagtcaa tatgttttga ctttttttaa gtacacacgt atactaaatt taagaactta
     4861 tcctgaggag gagttttcat ggagatagac aagcaagcag tcggcaatcg aattcggcag
     4921 attcgccaag aattaaagtt gagtatggag aaatttggca aactaattgg tgatttaccg
     4981 cgaagtacag tcaataactg ggaacgtggg atcaaccttc caaaaaccga aacccttcac
     5041 caaatcgcag agataggtca tgtcaccaat gaatatcttt tgtatggtga tcaagagaat
     5101 caatacattt tagaaatgct ccaaaaaaag gcaggtaagc ttgatcctaa gattgaaggt
     5161 ctcatagtag acgaaatcaa acacgctgac cttgttagtg aaaaagaaat ggatcgaatg
     5221 attgaatttt ttattacaaa tctcattcca ccaactgaac aagaccagtt tactttccaa
     5281 tgtatcgatg aaaaaaagca gctttatctt ggttcaacta attttggtaa ggaagcccag
     5341 ctctatttgc aacatgataa tcaaaatcat attctgcaca tgatgccctt taccttctcc
     5401 aactttagtg tggatcgcat actcgtctat ttagcaaatc aaaaatccta ttcctatttt
     5461 gggaaacatt tacccaagga actaggtgag aaagccatcc ttctatactc aattaatcaa
     5521 ttgaccagcg atgtgcgaat tgccccgttg gtctattcag aagaaaccgc ttcttatcag
     5581 tacacagagg acaatcaata tctactagaa cagcaatatc tttatctacc attcgtgatg
     5641 gaagtcgaga aagaacgcct gttaaatgca gcgtatccat catcaaaatg aggtgacaaa
     5701 attgataagc acgtgacaaa gaaaatactg ctaggacact ccccaatggg tagttgtcac
     5761 agtttcctgt tctttgttag ccccctgtta gaaccggggg ctttattcct gcagtccggc
     5821 tacgccttcc tgcaatagac aaaactccag atcgggtaat tcgcttgtgg cgaaacccga
     5881 cctggagttt gtctctgtat tttgaaccct aaaaattaat caaacagact gatattctca
     5941 taatcagcgc gaaataagcc attaagtaca gttttcctac ctatttttga taacccgctg
     6001 gttagttaat attccttttc cgagagagat aaatgattgg ttaaatctat atacatctca
     6061 acctttaaaa atgttttcga aatacttcat cagtacatgt catacaaatt accagtgcat
     6121 tctcaaattc tagttcttta attgatttca gttgaggagc agttactttt ggcggaaatt
     6181 tccatttttg tccaaacctc ttcccccgat gaaatttctt tgttgcaatt attgcaatga
     6241 aaaatttttg tttcaaaaat atacataatt acttcctcca ataaaaacta tctacctctc
     6301 aaattatttt tctctaataa gaaaaacaga aaaggtaata agatacaaca gtgatgattc
     6361 ctaataaaga aaagactaca ataatatttt tctaacttat cgccttcaaa gaaatagttt
     6421 cttatttttc actaaaataa aaaatttatt gcaaaaaaaa tagaagtgac aaaattatca
     6481 atcatttcaa ggtaatataa ctacctgagt ttattatcga ttaaaatgct aactacattt
     6541 gcaagagaag cgagagttaa aggtaaatat agaatttcta cttttttagc aatagaaata
     6601 ggaataaaat atttaaaatg tatagaaact ttcttttttt tcttgctatc tttttataat
     6661 cacaactctc tataatagaa ttacgattta ttttatacgg ctgaaaaaat ctatcaccaa
     6721 aaaaattcaa acattaagcc aaggattatg aagtcaacat ttcgaaaaat gaacatacat
     6781 tggtaagcaa ctataactat taccacagac ataaagtaac acaatatatt actatttaag
     6841 tgtacgccac cagtgaatat cctcaaggta tacagcgcac aacaaaaaga aaaaaggaaa
     6901 cgcagaagca tttcctttca gtgatttaat gaaaacaaca cgatttgact tagagccttt
     6961 ttatttgaat tcattttcgc tttatccaac ttcatttgat catttgatta ctcggttaaa
     7021 tacttttgac atgagtatca atgaaacatt cattaattat ggttgcttat ttcttaccgc
     7081 ttttctggcc aatgctaatc cgccgattat tccggcatta tcacctaatt cgggcgtaat
     7141 aatgtagcta tcaattggtg gtatttcaac atatccattt ataagctcaa caaatttatc
     7201 ctgaactttt ttcttcatgt gttcttgttt cattacacca ccgccaaaaa taattctatc
     7261 tggcgaaagc atcagtgttg tattgtatgc acattgggca aggtaaaagg cttcaatctg
     7321 ccaaaacgaa tcgtcagcca ataaattctg gccttttaca cccaatcgtt tttcaatcgc
     7381 tggtcctgct gccatcccct ctaaacaatc ttggtggaag ggacagtttc ctgaaaaatt
     7441 gtcctttgga tgtcgcttga tcaacatatg ccccatttcc ggatgactga acccttccac
     7501 gaaagtccca ttgaacaagg caccacctcc gatacctgtt cccacagtga agtatgcaac
     7561 acctgctaac cctttgccag aaccagcaac atattcacca tagcaagccg cattgacatc
     7621 tgttgtccat tcaatcggaa tattgaaata ttgctttagc gttcctacaa aattgaaatt
     7681 ttgccaagca agttttggtg ttgatgtgat atgaccgaaa ctcgttgatt tgcattgaat
     7741 atcaattgga ccaaagcagc cgaccccgat gcctgccaat tgttccttaa aaggtttaaa
     7801 aaaatcaatg acctgcttca ttgtttcaac tggagttgtt gtgggaaaac tgactctttc
     7861 caaaatcgtt aattcctcag taccgactgc acagacaaat ttagtccctc cagcttcaat
     7921 tgccccatat atcatcatag gttcctccct tcgaatatgt gaaaaacact tcattaacgc
     7981 ggcaagcgtt ctcgatcagt gaaatgacgt ttagtatttc ctgaagcttc tgttgaatac
     8041 caataggcga cactagcaac atcgtcttgc cgctcaaata agcgaacatc atcgttgccg
     8101 atttgttgta aagtgaccga taaatcttcg gtaaaacaga tggggtcttg aagatgccaa
     8161 cgataaagac catgtcgtgg cattgcgtcg tcaccaaagg catgaacggc attcaatttt
     8221 cccgtttcaa aacgatctct tgtggcatct ctatttgatt ggtaaggata ccctaaaaag
     8281 gctgttgaat agtttttcgc atgtggacgt ccgaactcat cgtactcatg aaaggcccac
     8341 gccccgccaa aataatcttc tgaacctgtt gaggttacgg tcggatactc actatcccca
     8401 tcaatgtaga atttaaactc gccttcgccc caccaataac gttctaggca ggtaagcgca
     8461 aggtaagtac ccacgtaata gccttgaccc tttaatcgat caattaactt ataatcctcc
     8521 tgtaatttgg taatgcgttc ccgatgccaa tttgcgtgaa aatataggct attttcttcc
     8581 aattcgtcca ccaaagcgta atttatcgta taaaaaaatg aggacatatc cttcggatgt
     8641 aaattctcga tcgtaatttt agcggatgtt tggaaaggca tttcgaaata ggaattaaag
     8701 ccccccgtag gattaaccac tataggcaac gagttcacct cgcaacgctc tccaaaccca
     8761 ttacaaaaga aatcccctaa aggactttca acagccgggc tatccgaccc atcccaataa
     8821 attcttaaga ttaaatcacg taaaacaaaa ctgccaaatt ctgttcgatc acgaatcgtc
     8881 atccacatat gacgaattat tcccgttcca gtaatatccg caatcacagt ttcttcacca
     8941 gaagtcagcg gaattgcgcc acgacctttg cggcttggtc ctagctcgct tggcaacatc
     9001 gcagctttac ctttctcgcc tgttggattt tcgggagtga ttgctcgact ctggattttt
     9061 ttaaattggg taatattttt tagtatactc atctttttct cctttgaatg taaatcgttt
     9121 ttcccttttc tacgtgaaga atttttttcg tatcacttat tttcaatggc ttttctgaca
     9181 aatttgaaat actcaactcg gattgcgtac attcaatcga aatgaaggct tgaccgaact
     9241 tcaaattttt ccaagaaaac gttaaattat caacaggatc aatttgcaat actccttttt
     9301 tgaatttcaa tccgaaatat tgactgatca ttatactgac aaaaaggccc gatgcccagc
     9361 cgcatttgcc gcagccaaag tctcgcacaa cttctccttg tttagcctct aaacgatacg
     9421 gccaccacca ccatgaaccg tctaaatctg ccaaacaaat cagctcctct aatcgggtta
     9481 cgaaggcttg atggttgtgc atgtcactca ttaaaacagt gataaagcca ggaaaagtgg
     9541 cgccggattc taatccccaa gtgatgcctt tgatttcctc gctataagtt ggattgaaag
     9601 aactagcaga aaaggtcatg gtgttctgat ataaaggatc tttattatct aaaaattgat
     9661 aaaaaggcat caacgtagtg tctgattctt ctccatcatg catcaataaa ttgattttcc
     9721 catccacaat cacatcactt aaaaagatta acccttgctc aagaatcggt ttttgatagt
     9781 tcttcactga ataggttgtt ttctcctcat caccgatccc ctccaaaaat tgctccccaa
     9841 aagtaccatc tatggtcatt tgtttacaaa ttgattcctt tagtttacag gcgatgtctt
     9901 tgtatcgctc gctaagactc agttgttcta gggcttcaaa aatttctgca agtccactac
     9961 aggccttcca aagacaaaga ttgctgccgg tatgatactt tccaagtgca aaggcgtctg
    10021 ataaccaaac agatggaaaa agcattggtt cccctgaccg acgttgagct aatatgtcct
    10081 caataattct tgaagcattc agtagaacct gcggacaccg ctcaaagaat tttgtatccc
    10141 cagtatgttc aaaataaaga ctagccagta acgcactgga taacgaatta ctcagagaat
    10201 gattgatacc tcctgtaaat tttgaaccag gaaacttaac gccatattga tcaaaccata
    10261 gaaccgtttt ttgacataac tccggttcaa acatggtgaa tggcaatgat gcgtaataca
    10321 tatccttatt ccaaattcga ttagtagcag gatagctgcc ccaattgctg ccgacgacct
    10381 gtccctgtcg attcataccg aaactagaaa agctttgata aagtgcacga cgatagagat
    10441 ggacaactct atcgtctgac attgacagct gcccaaatag ctgagcaaaa tagttcattg
    10501 tttccttcag ccatttttcg atatcagatt cctgaaaagt cattacttct tcaaaagcat
    10561 ttgggtccac aaaagcaatg gcgaagcttg ccacttcctg ttgtgcgatc gtgtccttat
    10621 ttcctttttg agaaatcaac acattttgct gatccgaata cttctcttgg tacaaaggca
    10681 catctttcac tgaaacttga aggctttcgt gtgtttcatt cacaatgtaa acctgttgaa
    10741 caagcatact taaacgctta ttagccagta ttggagcaaa ggatactaca atgaccttaa
    10801 acgtcgaata atgatgaata tatctaggca aacagtcttg aatcacatcg acttcaatac
    10861 gatgatccga ttctgacaaa tggtagacaa tcccgtttac ttcaaccttt aaggataacg
    10921 aattggtttg agaaagctgt ttattgaccc aaacacctgg tttttcctca gttagtaaat
    10981 tttctcgata aaaggtcaac gtttgaatcg tcccgcaaac atcaaggttt cctaatgtct
    11041 tttgattact tacatcaaag gtcaatccct ttacatcagg aatattccga tagtagctgt
    11101 attcgtttga agtagtcaca tttccgtcgt ttaactcagc attaaataat gggtgtttgg
    11161 gtgaataaat tacttcatta atagtcatct tttccctcct tgctaaaaaa actgcagcct
    11221 agtagctgca gcttcctact atgcgattcc aagtaatgac aataaaattc ccaagacgac
    11281 cattccaaaa ataattttga tgacgccgac ttttttatct agtaatttga aacagcccaa
    11341 tgttaccaat aacggtacaa ttcctttaaa aatactatcg aggatttctt ggacattcat
    11401 tagttcttcg cccttcattg aaaagctcaa aacggtattg aatttgacca tactgatcgt
    11461 cattgcgcct accatgatca gacccaagat actagcagct tttgtcagaa tttcaattaa
    11521 cccgttcgca tacagctttt caatatattt agagcctaat gaatagccta aaacgccgcc
    11581 atagtatcgc atcaaataat taggtatatt gaacataact aaaaagataa ttggtgccaa
    11641 aatatttccg gcattggcta agttgatcgc tagtcccgcg gtaacgacac gccaaactcc
    11701 ccagaacaat gaatcgccaa ttccagccaa tggtcccatc aaactcgttt tgatcgcgtt
    11761 gatactttcc acgtcaaaac cagctttttc agaattttcc ttctccatcg atgccgcaat
    11821 ccccatgaca aaggacgcgc aaggaatggt cgtcgaaaaa tactgtgtat gacgttccag
    11881 cgccgcagct cgatcttctt cacttttgta gaaatgatta atgaagggca tcatagaata
    11941 ggcgaaacca ccgccgccca tcgtcaccgg attcaccgaa gcatacatgg tcatcgagcg
    12001 ccaaaacatc ttccgaacca attttttctc atctttagaa attccatcag ctaatttcat
    12061 tgaaagaaat cctcctcttc ttggtcaagc gttgcattta cagcagcatc gctttgaact
    12121 gcatgaacag atatattttt tagttgtaga tctctttggg ctataacaat tgcaataatc
    12181 gttccaactg cggcaattgc aatcaatggt aactcgagat acgccataac aacggcccca
    12241 aagaaaaacc acacagcaat atttttactc caaagcatcc gtaacagcat cgccatccca
    12301 actgccggca gcagatttcc agcgactgtt aatccgttca tgatgacctc tggaatatta
    12361 tccaagacgc ttttgacaac atctgctcca aataaaacgg caaagaatgg aataagagca
    12421 taaagcgcat agtggacaaa ccacataacg aagtgcagat tgatgattcc tttttgatca
    12481 ccagattttg caaatttgaa aaatttagca gccatcggtc cacatacaaa agaaaaaatc
    12541 atattcatta actgtaatcc taatactgct agtggaaaga caatgggaat aatcgcatcc
    12601 acgtttcctc ccattttgat tgcgaacgct gtagccaacc cagcagccaa agaaggctcc
    12661 gccgtactag agattccgat attgacgaca cccataaaaa tggcttctag tgacgccccg
    12721 acaatcaacc ccgtctgcaa atcccccatc aacgctcctg ctaacggagc aacaacaatc
    12781 ggacgactca gcatggacat cccgaacatt tcatgtccag caactccaat aaaaacggcc
    12841 aaagcgacta caaatgcatc atacataatt tttctccttc ctttttctaa aaatcactca
    12901 aaatagagat agctgaacgt ttttccatcg ccggtgtagg ctgaaaaacg gtatctggat
    12961 aaagttcaac taattctttt aagtcttgaa tttctgacgt cgttaacatc acttcctttg
    13021 ataaggtttt cttatcttcc gatggcggtg tcattttccc agcattcccc acgttcatta
    13081 attcgatttc cgttgggaaa gctttcgcaa cttttaccgc atctttgaca ttagggacta
    13141 aaaccatcaa gcgcatgtcc ttcgcccgcg gatcttttaa caaatgaatc gcgtcatcaa
    13201 ctgttttaat aatgactttg acattcgatg gtgcagccat cttcaatgtc atcttttgaa
    13261 tatcgttggt agccgcctca tcgcttgcta ctactaaccc ggttaaattt agactctttg
    13321 tccaagtcat cgctacttgt ccatgaatta atcgttcatc aattcgcact gctttaatca
    13381 tttttcttcc tcctaaaaaa aatcttcctc ttcatttact acatgtacct catcaagaat
    13441 ggtcatcttt aattcctgtt ggcatttatt taccagttcc tgaatatcct cctttgttaa
    13501 ttccttggtt gccaatacta tttcgagcag aattggcaga ttaaagccag acaaaatagt
    13561 tacagcaatc tctttctcca aaaaggtttt ggtaatcttc tgattgacac ttccgccaaa
    13621 taaatcggta aaaacaaaaa tctgatcctg ctcgttcacc tggtttacaa atacattcaa
    13681 ctcctgttca aaatcacact catccacata agcattaatc accgtaatct cttgaacctt
    13741 ccccgtcagt aattgaatac tgctaagaaa gcctgaagct aagtgaccgt gagtcgctat
    13801 tagaattttc ttcatatggt taattccttt ctttctgttc acttttatat aagcaattcc
    13861 tgtgccaact tttaaaaaca ttggtttaat cacgttaatt cacattaaaa aaagtgtcta
    13921 acctaaaaaa aacagattag acactttttt agacacttta tttttgaata tacggtccta
    13981 ataattcata gagcagcgaa agctcataag cattgacttt aaaattatat ttcatctcca
    14041 ttgattgaaa aatacttcta gaaacataat aaaattcatc ttcatctggt ttcaaatcat
    14101 aattcggttc ttcagatttt tctgtccgag ccaagaataa acgttccatc atcaatgccg
    14161 tatgcatata gagatttagt tttacacggc catttaaagt gaaatgatag taattttcat
    14221 atttagaaat gactgtttcc acttcactca tcacgatcgt tgggttcaga aagttcaaac
    14281 ggtccgcaat tccttccaac gaaaagaatt ttactagctc ctgaatcaag cggttaaatt
    14341 ctgccggctt catttcagga ctcaaaatat gctccaaatt ggctgctcca tcaccgtcta
    14401 agatgtcata aacattaata ttaggaattg aaaaggaacg tggaagatcc gaagtcgtga
    14461 tgaccaattt tgtcttgtca aaataagttt catcattttg gtcgattaat tcacgtagtt
    14521 ctctgtagtc cttcgtgaaa acttcgatgg attcatccga taaatgatga cgaaaaacat
    14581 ctttcaattt gtccgaaatc cccaaacccg acatacagga aatgataatg ttgctacttt
    14641 gagaaaagcc ttcaaagtat tgaacattga ttgaatactt gtctgctgca tcctccgcaa
    14701 tctgtttaaa tggcgcattc atcgtcatct tcaagccaat atcaagtgca atggaagtcg
    14761 tcaaattatt cagaagaagt aactcccctt ttaaatcgtt cttgatctgt gtgtaaattt
    14821 gatttaaaga gcccatatct acgatcagca ctagactatc tgtattcact tgccgtttca
    14881 cgaaattcct tgtcgattcg acaatctctg acacattact ctctactggc atatccaacg
    14941 cttcaaaaac ataattgccg cataattgat tcactactgc ttgaatgctg ctagccgtac
    15001 tatctccgtg agcaagcaac aggcccttca gctcgatgga ttcatctaca taatcagata
    15061 aagtcacgac aataagcagt cttagaaagt tctcgtcctt ttctgagagc ggtggtaaat
    15121 gctccaagaa ctgattacat aagtaagtcg tccgaggtag atttgcagct aatgtacgat
    15181 ttatcccggt taagtctgtc ttatagcttg gggaaatgac ataggatctg ctaataattt
    15241 ctgcaacagg tccactcgtc gtcaatccgt acgtttttcc taaaacggat acccagacct
    15301 ttctaaacat ctgaatcatc aattttctac tcattgataa aaaagaatcc ttatcaatgt
    15361 gatgcaccaa atgctgtact tcattcttta tcgaagaaaa attttcattg aaattacctt
    15421 catttatcag ctgagtaatt ttttccaaaa tcgaatcata atcaaacggt ttgattcgat
    15481 ccgtttttat cttttgattt ttctttatca ataaactagc aatcggcaag ctttctactt
    15541 cggattccag catatttaac tgaatcaaga tctcattttt cccaatcgtt aatggttctt
    15601 cttgtgttcg actatacaca tccgcacaac tgattttaat gatattcttc agcttaccaa
    15661 tattcccact aaagggatga gataacatta aagacaaggc ttctcttgaa acaataatat
    15721 ctttttgtaa aacatccgct tcattttgaa aaaataattg aatcagctct aatcgttctc
    15781 gaatggggcg atcttcaaaa gttggcaaca taacactaat ttgaatacgc cgatcaaagg
    15841 tgtctaataa ataattttca cctttttccg tcgtggcgaa aataaaacga accttagcag
    15901 aatgccaatt tacattttca ccgactggac gatagtttcc agtatcaata aatagaaaga
    15961 gcttttcttg attttctttc gataggcgat ggacctcatc gagaaaaaga tagccgttgt
    16021 tggccgttgc caataaacca tcggtatcct tttcagcccc cgtaaaggcc cccttcttgt
    16081 atccaaacag tgttgccgaa agcagttcgg gattgtccgc ataatcggca cagtttaaga
    16141 tagcaaatgg tgcatctttt tcaataattt gctcatggat agcgtattca aaaatttttg
    16201 tggctaaaaa actttttcca acacccgtgg ctccatttat taatacactg agtccgttag
    16261 gcggatattt gacagcggct atacattttt gaatgacctc tctcagactt ccgtcatgac
    16321 caactacaga atgaaaggct tcgtttattt gctccgtatt atctacaacc gcatattcat
    16381 ctaaaggctt ccacaaaaca ggctttcccg gtaatttctc gaccttttta tcttccacta
    16441 atctcgtcaa ataatggctg gcattctgac gagagatacc tagattcttc gaaattttct
    16501 cggcagtgac agaagacata ttccctgtta gtcgtatcag ctcatcaaaa actcgatctt
    16561 tagcgctctt tttcattttt tcctccagtt taatgtgtct aaaagcataa taaactatcg
    16621 gctgcaatat gtctattcta tatttgtatt ccaattttta ctttgaaaca caaatagtcg
    16681 aatatttgcc tcagatatct gacaaaataa tttatctacc aatttagttt ttatctaata
    16741 tgatttttat gttttttcat agctacaaat attgaactgg attcatatat tagttttatt
    16801 aatagattac agaagggtta agtatatttg catagtttcc aattacttta tccttctgta
    16861 actttttcaa tcttagattt actagcccgt ctcgggccct attttacaat ggttttgtcc
    16921 acttttctct ggtagaaaaa cgtggtagaa aaaataaaat aacacaaaaa aagcggcgtt
    16981 tcatccgctt ttggtagaag attggaaaac tcagatagaa aaaggacgat ttttagctct
    17041 ttagaacgtt gataagtccc cattcttact gagttttgcc attatctcct atacatcttg
    17101 aattctaaga ataggtcatt atagatgcct aggtatttcg atcctagatc tttgtagact
    17161 tcaagatggg agatcgtgtc atcagatgga tagaattgtt cgtccgacga aatgtctttt
    17221 ggcaataacg cttttgcttc ttcatttggt gtagaataac caatatactc tgcattttgt
    17281 gccgcatttt ccggttctag cataaagttg atgaaatcat aggcaccttc tttatttttc
    17341 acggtttttg gcataacgat attatcaaac caaagattgg atccttctgg tgggatcaca
    17401 taatgtaaat gttcattttc ccacatcata tcggcagctt cgccagaaaa tgtcactgcc
    17461 acggaggctt cttcattgat catatacatt ttgatctcat ctgccacgat tgctttgaca
    17521 tttggtgtta aatgattcaa tttatttgct gcttctgtca gctgtgccat attcttacta
    17581 ttcaaagaat agcctaaact attcaaagaa agccccataa cttctcgtgc accgtcaatc
    17641 agcatcaaac tgtcttttaa ttccggcttc cacaaatcat cccaatgctt aatttgattt
    17701 gcatcaaaga atttatcgtt atatacgatc cctaaagttc cccaaaaata tggaatcgaa
    17761 tactgattat ctggatcaaa atccaagtct aaaaatcgtg gatcaatatt atttaatcct
    17821 ttgatcttcg aatgatctaa tggaagtact agtttttctt tgatcatttt ttggatcata
    17881 tattcacttg gtatagcgat gtcgtagttt gtcccacctt gctggatttt tgtgaacatc
    17941 gcttcattag aatcaaatgt ttcataattc actttgtatc catattcttt ttcaaatttc
    18001 gtgatcaaac taggatcgat ataatctccc cagttataga tggtaagtac ctttgctcca
    18061 ctcatgccac ttgttttttc aagttgacga acaccaagca gcagcaccgc aataatgatg
    18121 agaataccta aaaacagaga ttgtaatttt ttcatcgcag ccgtgccacc ccctcgcgta
    18181 ctcttctgtt tttcttcagc cgttttggac ggttttcttt actaataaag tagtatccaa
    18241 tgaccaatat catggagaac aagaaaacta acgcacttag cgcattgatt tctaaactga
    18301 ttccttgtct tgcacgagaa tagatctcta ctgagagcgt cgtaaagcca tttcctgtga
    18361 cgaaaaatgt aaccgcaaaa tcatcaagag aataggtaaa tgccataaaa tatccagcta
    18421 tgattcctgg agaaagataa ggcaaaatga tatttttgac tacttggaaa ttattagcac
    18481 caaggtctct agccgcatcg accattgaat cgttcatttc ctgcaatttt ggcaagacca
    18541 tcaagacgac gattggaatg ctgaaagcaa tatgggaaag caatacactc tgaaaaccta
    18601 atccgaatcc tagtagtgta aagaaaatca agaaactagc accgataata acatcaggag
    18661 agactaataa gatgttattc atgctcaaca acgctgtccg tgcacgtcgt tttttcgtgt
    18721 aatagattcc catagcccca aatgtcccga tgatcgtggc gatcaatgca gataagaaag
    18781 ccagcatgaa cgtattcaat acgataatga tcaaacgtgt atcttcaaaa acagcttcat
    18841 aattttccca agtaaatcct gtaaagctgt tcatcgttcc tccttcattg aaggaataaa
    18901 aaatcagata gaagatcggt gcatataaga ataaaaagac gatccctaaa taaagatacg
    18961 accatttaaa ttttttcatt tatgagcgac ctcctttttt cttctcgcct gtcaggagca
    19021 tcacgatgaa catagcaatg attaaaatca caccgattgt agaacccatc ccccagtttt
    19081 gtgtaaccaa gaaatgctgt tcgatagccg ttcctaaagt gatcacccga tttccgccaa
    19141 tcagacgagt cagcatgaat aaagaaagag aaggaataaa tactgcttgg acaccacttt
    19201 tcacaccatt taatgataac ggaaaaatca ctcgtcggaa ggtctcaaag ctattcgcgc
    19261 ctaaatctct actagcactg atcaaagaag gattcatctc ttccaatgca ttgaaaattg
    19321 gcataatcat aaatggaatc tcgatatacg ttgccacgaa cagaaaactg aagtctgtga
    19381 ataatatctg tttcggcccg atcccgataa aatcaaagaa atgattcacg ctgccgtgca
    19441 cactgaaaat cccaataaat gcgtaagctt taagcagcag attcacccat gtaggcaaaa
    19501 taatcagcat cagccataat tgcttgtgct tcagttttgt taaaaaataa gcagtcgggt
    19561 aactgatgat cagcgtgaaa aacgtgatca aaaatgcata ccatacagaa ttgatcgtca
    19621 tagaaagcga tgtccccgac gtaaaataag atagataatt attcagcgtg aattgcccat
    19681 tcatatcaaa aaaagattga taaatgatca ttaatacagg cgcgatcacg aataaaccga
    19741 gccacaaaat ataagggacg gaatagatcc tgcgcattgt tttcattctt gtccccccta
    19801 ttcttcgtag ctgtcaagac gtgcatcgaa ttcttcttca gactcgttga aacgcatgac
    19861 atggatatct tctggctcaa aggccaatcc tactttgctt ccttctttag cttttttcgt
    19921 tgaatggacc atccattcat tttgctgttc atcataacag atgatttcat aatggacacc
    19981 acgaaacagc tgagtatcga ccgttacgac tagttttcct ttatctggtg tcgtgatcgt
    20041 caaatcctct gggcgtaaaa caacttcaac tggttcattt agacgcatcc cgccatcgac
    20101 acattcaaat tgcttaccaa caaactcaac tagattatct tcgatcatta caccgtccac
    20161 gatattgctc tccccaacaa aatcagcaac gaaatgattg attggctcat cataaatatc
    20221 tacgggtgta ccactttgga cgattttccc tttattcatg acaaaaatct catcactcat
    20281 tgccaacgct tcttcttggt catgagtaac aaaaataaac gtgattccta atcgttgttg
    20341 cagatcccgc agttcatact gcatatctgt acgtagtttc aaatcaagcg ccgataacgg
    20401 ttcatctaat agcaatactt tcggttcatt tacaattgct cgtgcaatcg ctacacgctg
    20461 tctttgacca ccagacattt cactaatctc ccgtttttcg tatccaggaa gctggaccat
    20521 acgcaaagca tcttttacct tcttttcgat atctgatttg gacattttct tgatcttcaa
    20581 tccaaaagca acgttatcaa aaacattcat atgaggaaaa agtgcataat cttggaagac
    20641 tgtatttact tgtcgcttat tagctggcaa atcattcaac cgtttccctt caaaatagat
    20701 gtccccttct gtagcttcgg tgaatccagc tataatacgt aggatcgttg ttttaccaca
    20761 gccggaagga ccaagcagtg tataaaattt tccttgttcg atctcaaaac ttactttttt
    20821 taatactgtt tcatcatcat agcgtttcac tacttgatca aatgaaatga ttggtttccc
    20881 cacgttttta ccccctatat tacaaatatg attgcgttgc aacaatcaat acttttgttc
    20941 gttttttgag atgattcctt aattgatgtt gttttgtcgc ttgataatag atcgactgtc
    21001 ctgcttttgc cacatagacc gtctctccta agcttaactc taattcccct tctaatacaa
    21061 aaataaacgt ttcagataat gaaggttcaa acgtcttata ttctcctgca ccttcaaaag
    21121 tcagcaagac aggctccatt tctttttcat tcgaatcagc cacgagccat tccaattcat
    21181 acccgttttc ttcatcgaaa taaaccgtat gatcttcttt tgaataaacc acttgcagat
    21241 tcgctgcttc ttgatgaaaa aattcttctg gagtcacacc taagacttca agaatagaaa
    21301 agaatgtttc cattgatggt gaacttaaat ctcgttccaa ctgggaaata tacccttttg
    21361 acaaatctgt gcgttcgcct agttcttctt gtgtcaaatt cttttggatg cgcaaatttc
    21421 ttaacttctc accaatttcc ataatttcct ccgaatcgaa gttttctaat agtaaacttc
    21481 ctgtttacta ccactcgtat tagtatacga aatttattga aaaaggcaac cctttgtaaa
    21541 attttttttg ctgaatattt ctttatcttt tggaataaat tctagttgtt tgattcttta
    21601 tttttcacct aatttttgtc taaatttacg gaagaacaag aataaaagag taggctttat
    21661 ggtatgataa aagaaaattt taaaaggagt gtctcacgaa tgaacgcttt tcgatctttt
    21721 caggtaataa aggaacctgt tttccataca gcaatcagtg atctgccatt tactgagttg
    21781 gctgaaaatg aagtcttggt aaaaattgcc tattctgatg tcaattataa agatgcattg
    21841 gcaatgagcg agtctggtca ggtgatacga acatatccga tgactccagg gattgattta
    21901 tccggaactg tcgtccaaag taacaatcca cgtttttcaa aagaagatct tgtacttgct
    21961 actggttttg ggcttggcgt cacccatcca ggcggttata gccaatatca aaaagtacca
    22021 ggagactggt tagttcctct accaaaaaat atgacgctgc gtcaagcgat gatccttggt
    22081 acagcagggt ttactgctat gttgtgtgtg aacgctttaa tccgtcaagg tatgacctcc
    22141 gataaaaaag ttgtcgttac tggtgcttct ggcggtgtag gcagtacagc gatagccctg
    22201 ttacataaac taggattcca gtcaatcatt gccttttcca gaaaagaaga gtctgtcaca
    22261 tggctaaaaa gtctaggtgc tttgcaagtc gtacgacctg atgaatttct gccagagaca
    22321 acaaaagctt taggaaaaca gcaaatcgac tatgtcatcg acacagtagg tggcgagcag
    22381 ctaagcagtc ttcttccatt gatctcttat aacggtgcag tagctttatg tggcaatgct
    22441 gggggaatca aactaaacgc gactgtcttg ccttttattc tgcgaaacat ccagttgatt
    22501 ggaattgatt ctgtcaatgt accaatagat caacgtcttt ctttatggca acagatggcg
    22561 gatttgcaga ttgcagatga actggtcgtc caagagatta ctctggatca attgcctgaa
    22621 acagcatcta aactacttgc tggaacacac caaggaagaa cactagtaaa tgtaggtgac
    22681 cataaatgaa gattctaatc acagctggag gaacgactga aaaaatcgat caagtacgtg
    22741 ctattacaaa tcattcgaca ggacgattag ggcaagcatt agctgattat ttagctgcca
    22801 atccggatac cacaatcgat tacgtgacta cgaaacaagc actgaaaccg aaaagacact
    22861 ccaatataac gatttatacg atcgaatctg cactggactt atttttacaa ttagaagaac
    22921 taacgaaaaa agaacactac gatgcgatta tccacagtat ggcagtcagt gattttactc
    22981 ctgcttttag tttttcagaa gaacagctgg caaaaaacct acccacttct tcaacgcaag
    23041 aagaactgga caattggttt gcggaaaatg aacagacaga taccactgtt tcaaagatct
    23101 cttctaacac cgagcatctt gtgctcgttt tgaagaaaac accaaaaatc atttcttatc
    23161 tacgtgaatg gcagccaaaa gcaaaaatca ttggtttcaa actattagta gatgtaccaa
    23221 aggaatctct tctggcagtc gcaaaaaata gtctgataaa taacaaaact gattttattt
    23281 tcgcaaatga tttgacggaa atccatggcg agacacacca cggctatctc ttatctaaag
    23341 atggaacagt ggaagaagct caaagtaaat ctgagattgc tgcattgatt actgagaaaa
    23401 ttagactgga ggaatcaaaa tgaaaaagat cttactaggc gttactggaa gtatttctgc
    23461 ttacaaaagc gctgatctta caagtcaatt cgtcaaatta ggtgcccagg tagatgtgat
    23521 tatgtctaaa agcagcacac attttatcac gccattaacc ttgcaatctc tgtcgaagcg
    23581 cgcagtccat acagacgtca tgcaagaatc aaatccgcag gtaatcaatc atatcgaact
    23641 agcaaaacaa gctgacttgt ttctcatcgc gcctgctaca gcaaacatta tcggcaagct
    23701 agcaaacggc attgcagacg atcttctttc aacagtcgca atggcgcttc cagtgggaac
    23761 accaaaattg attgcccctg ccatgaacac gaatatgtat caaaacccga tcactcagcg
    23821 taatctggaa acattgagat ctgtcggcta tcaggaaatt gaaccaagag aatctctttt
    23881 agcttgtgga gattttggaa aaggtgcctt agctgatatt cagacgatca tcgaacaggt
    23941 catgctgact cttaatgaaa gaaatgctta gaaaaaagga gtacttatga aaaatacaaa
    24001 aaactttaca ttaactgcga tgtttttagc tattttgatt ttattagctg ttacgccttt
    24061 aggttttatc cctatcggtc caatcaatgc aacaaccatg catattcctg taatcattgc
    24121 ttcgatcgtt ttaggaccaa gactaggtgc ttttcttggc ggtacatttg gactgatcag
    24181 catgatccgt agcacagtta tccaaacacc tttgtctttt gtcttttctc cgtttatccc
    24241 agtcatcgga acagaacatg gaagctggaa agccttgctg atcgcgttta ttcctcgcat
    24301 cttgattggg gtggttcctt atttcgttta taaaggtctg cgcaaactaa tgaaacaaaa
    24361 agcagattcc gtttctttat tcttagctgg actttccggt tcattgacca atacgatttt
    24421 agtgatgaat atgatctact ttttattcca gcaagattat gccaaagtca tcggaacaaa
    24481 tttaaatgct gtttattcag ctattctagc ggttattttt acaagtggta tacctgaagg
    24541 aatcgtcgca ggtcttgcga ctgcagcagt atgcaatgtc ttgttaagat acttcaagca
    24601 cccttctctt actaactgat agtcatcgta gccgatctct gatttttttc tcttttggtg
    24661 ttactattga atggaaagat ttgacgtcga aaggatgatc caaatgaaaa tttttgttgt
    24721 aggtgcaaac ggacaaattg gccgacacct gataaaagat ttagctccaa gttcccatga
    24781 aatttttgca ggggtgagag atgttgcttc ccaaacatta gtaaaaaaag agaatgtttc
    24841 gtatgtctct tttgatttaa cttggtccgt ggaaaaaatg accgaagcat tcaaaggcat
    24901 cgatgtattg atttttgctg ccggctctca aggaaagaat cttctgcaag tagacttgga
    24961 tggcgcaatc aaaacagtga tcgcagctga aaatgcgcat gtctctcgct atctgatggt
    25021 cagtgctgtt tatgcagatg aaccagcaaa atggcctgag tccatgacag attattatat
    25081 tactaaacat tatgcagatg aatggctgaa acgaactaac ttagattttg tcattcttca
    25141 accagtcaca ttgactaacg atgaagaagt tacttccatt caattaacta agcctaatga
    25201 gaaggcatca aaaacgatca ctcgctctac agttgctgct gtacttgccg ctctagtgga
    25261 agaaacggat atttctcgta cgactctagt actttctgaa ggtagcaaag agttgaatac
    25321 agcattccaa gaatgggcaa aggaggaata gatccatgcg tgccatttca atcaagcatc
    25381 ctggttctgt agatgtatta gaacaaattg aagtgcctgt tcctaaacca aaacaaggcg
    25441 aattactgat caaagtccat acagcagctg tcaatcgaac agatattatg aaaagagaat
    25501 cagtctcttt gaaacctccc taccctattt tgggagtcga agtagctgga gaggtagttg
    25561 agaataaaag tgatatctcc acttttactc ctgggacaaa agtatacgga ttagtcaatc
    25621 taggtggtta tgccgaatat gctgtgatgc ctgccgatcg tgcaatcctt ctccctgata
    25681 cgctagacta tgtttctgct gctggaatct cagaagtttt tttgactgct tatcaaacac
    25741 tttactggct tggaaaatta caagaaggcg aaactgtctt gatccatgca ggagcaagtg
    25801 gtgtgggaac agcagcgatc caattagcta gacagctttc tcacgcgaaa atcatcgtta
    25861 ctgcaggatc agaagaaaaa ctcgcctttt gtaaagaact tggtgcagat gaattgatca
    25921 actataaaaa acaagacttt caagaagagg tacgaaaaat cactgaaggt cggggagtcg
    25981 atgttatttt ggatttcatc ggcgcttctt actgggaaaa gaatttagct tctatagccg
    26041 ttgatggacg ttgggtcttg attggtatgc taggtgggac catcgtgcct gagatagacc
    26101 ttggtgtatt gattgggaaa cgtgtccaac tgcttggtac attattgaca cctagaagtg
    26161 atcagtataa agcagagctc gcacaaactt ttatgcaaaa agctgggcct tttctagaaa
    26221 atggcaagat tcggccaatc attgaccgta cattccaatt cagcgcagtc aaacaagcgc
    26281 atgaatatat ggaagcaaac aaaaacatcg gaaaaatcat tttgaagata actgaataaa
    26341 atcatgctga tcaaaaaaga ggctgggaca gaagcgttta actccaagaa ataagaagaa
    26401 attcacgaaa attgcttttc aaatttttgt gaatttcagc ttatttccga aggaatttct
    26461 tctgcttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt tacttttgtc
    26521 ccacgctctt tttccgaata aacggtgttc aaaagcttgc atctgcggta ataagtccaa
    26581 ccaagttaaa aacataagaa gctgttttta cttggctgtt cttattactt gatgcagggc
    26641 agctttttca caacctcttc actaaacagt gttcaatcag ctgaccctcg gtattagctc
    26701 aaaacgctgg tttcacaacc tctttttatt tacgttctat ttcattcatt ttccgaagca
    26761 aatcgagctg cttgtatgcc cgcttgtcgc ccaaaaataa tgatctccgc aactgaattt
    26821 ccaccgatcc ggttgtttcc atgtaagcca cctgtgactt caccagcagc atataacccc
    26881 ctaattggct ggttttcttt atctaatact tcagtgttcg tattgatttt cacaccgccc
    26941 atcgtgtaat ggattcctgg tgcgattttg atcgcataat aattcggaga cgataagtca
    27001 tgttccatgg ctgtggcacg gttgaattga gcatcttttt tctccgcaac atccgtattc
    27061 catccatcaa ctgtttttgc tagtgtttct tttggtaaat cgattttttc tgctaattct
    27121 tccattgtct ttccagttgt gacatatcct ttttggtcat aaaattcaat agctgtggca
    27181 cgatcacgca cgccttggtc aaaaatcaaa taagctgatt tttcaggcaa tgctgtaatt
    27241 gctgcagata ctttatccct tgtatccatt tcattgacaa atcttttccc ctcttgatcg
    27301 accaagattg ctccttctcc gcgaacaacc tcaccaatca agaccccctc atcctgctgc
    27361 acagttggat gaatttgtat tttatccata tcaacggttt gtccacctaa tttttcaatc
    27421 atggtgatac catctccagt tgatccttct tgatttgtcg taatataatc agctaaatcg
    27481 ggacgatatt tttcaataaa ttctttgctg gcaccaaaac cgcctgtggt aactacgatt
    27541 gcttttccgg tgacctcttt tggttcttct ccttgaacat gtacagtcac ttcattgacc
    27601 gtttccccat ttttcttaat gtctgtcaca tctgcgttga caaaaatagg gatttcccgc
    27661 tcatggacgt tattcaataa cccctccact aagtatccac caatagccga gccatcagac
    27721 ggacgatgtg tcctcttttc actcatccct ccagtgatcg ttaagttgtc cagtttgata
    27781 ccgttttgat ctagccaatc gaccgcatca gcagagtgat cgacaaagta tcgaagcatt
    27841 tctttatcat tcgttcctcc accacctttt agcgtttctt catagaaggc atcattcgag
    27901 tctttgattc cttcttcttt ttgaaatttt gtttctgaag cattcatacc gcttgatgat
    27961 ttagatgtgt ttcctccggc aacaggcatc ttttccaaaa ttactggatt caacccagca
    28021 tcttttgctt cgatagctgc tgccatccct gcaccaccag ctccaataat cacgacatca
    28081 taagattctt tcatttcttt tggatctgta tatacttgtt cagaagcgcc tgatgatact
    28141 tcggcagatt ccttcgtact agaacttgtc tgtgctgtat ttttctgatc tgcgccgcat
    28201 gcgctcatag caagaagtgc aacggctgtt aataaaccag caactaattt tttcatttgt
    28261 atcccccttt tctccttata ctatattaag tgattttttt cacaatatca actctgtttt
    28321 tctttaagtc atatagcttt ggtaaacaca cgcttcttag tataattaag gatatacatg
    28381 aaggagttat tttatgaatc atttgaaaac cttttttacg aacagtacaa aaactgcagg
    28441 tagaatcaca aacggaatct atattttatt acgtatcatc gtcgttatta tgctagtgga
    28501 tcaggtctgg aaccaacact ggggaaatac aatgctttta ttactgacat taattttatt
    28561 tgaaatccct tattttctgg aaaagatatt aaagatacag attccaaata tgctagaaat
    28621 cattttgtta tcttttattt ttagttcaac agttttagga gagttaagtg atttttatgg
    28681 ctatttttca atgtgggata cttttctaca tgcattcagc ggatttttag ctgggggtgt
    28741 cggcttttcc cttgtttatt tgctcaataa aaatacaaaa accatgaact tgactccttt
    28801 attactagca gttgtttcct tctgtttttc gatgacagtt ggtgttatgt gggagtttgt
    28861 ggaattttca gcagataaat tactgcaatt cgatatgcaa aaagatacga tcatccagca
    28921 aatcaatagt gtggagttaa gtaaagacgg aaacactgtc tatcatgttc cagatatcac
    28981 tcggacaatc attgaaagtc aaaatgcaga tggtaaaaca gataaaacaa tcatccaaaa
    29041 tggttactta gacgtgggaa tcatggatac tatgaaggat ttatttgtta attttattgg
    29101 agcagttgtt ttcagtgtat ttggttacct ctatagtcga aacgattacc aaaaatttac
    29161 gttcatcaag aattttattc ctaaaaaaat caaacgataa aacatgctaa aaaacaagag
    29221 aaggggcagt gacaatactt ttgtcactgc cccttctttt ttgaatgtat ggcatgccat
    29281 tagttatccg atagtattaa ctcaaaaaag taagatatga ggaatgacta tttcgttttt
    29341 tatcccaata ctgaggactt atttcaccat ttcgttattt atctaattta cttaaaacct
    29401 gcataacttt ttcataatct ggattaggtg tgccgtctag attttcagca ataaaagtaa
    29461 aacccatttt tttataaaga gcaatcgcct gatggctcca tgtctgtgtg tgaagataga
    29521 ttggtccgtc cgtatggagg gtaggaaatt cttgcaagac tctggcagtc aatgcttttg
    29581 cgagcccttt tccttggtaa tctggtttca ctgctaacca atgaaaaacc ggatacactt
    29641 gctctcttga tttttttcgc caagcggtac aggttgctac tttttctcct ttttttgtct
    29701 ctacaaaaaa catccttctt tcaagttctt caggataagg agcaaagttt tgttgaaaat
    29761 actcaagtgc ttcatctgtc gtttgaaatt ccccaacgga agtctcaatc tccgcccaag
    29821 cagattcatc ttctttttga taaaatcgaa attcaaaacc ttccgctaaa ggcgtgattg
    29881 gaacattttg ttgaagtggt cttgtcatcc agatttctgc gtaaggtaac gttttatcta
    29941 acatttttct atccctcctc gtctccatta tgccaaataa catatgactc agctacttat
    30001 ttgactataa cagatagaga tataaatcag aaccagtcat ctgcgtcaaa ttcatttcga
    30061 ttagcgtata cccatgttcc tgccatacct cgcatgaaat ctcctaaagc agaagaagga
    30121 atacctccac caggtgcggg tgttcccgga ctaggaagtg gtacttgcgg ctgcagatgc
    30181 tcatcggtgg aatcaatagt tgacaagcgt tttttcttcg tttccttctg gtcatctgat
    30241 tccttctgat cttccgactg tttagcaaca aattcttttt ctgattgttg ttttatttta
    30301 ggctctaaaa tttcattttc caatccagaa acttgtgggg ccaaatgagc ttcttgcctt
    30361 atcgttttat tagattctga gatttttcta gatattcttg ctaactctag gcttcttgtt
    30421 tgttttactt tccctgttgg agaaactgca tgagccattt gttgtttttt ttctgacaag
    30481 ctttcttctt gtcttttttg ttctttttga tctatctgtt tgtttaatgg taaaacatgt
    30541 aatagtgact gagcatggag ttcttggagt gaatacgggt catgataact atacataatc
    30601 gtaaaatcac ctgtttgttt ggtcaaataa ccatcctcca atggtacttc attgattgta
    30661 accgatacat cctttaacgg tacgggttta cctaaggaat ttgttgctga ttggatcaac
    30721 tcttctttgt ttattttttc gtttggatga acaataagat catgaccttc taatgaacga
    30781 ttgtctggta tataaacata agtaaaggta atttcccctc ctgattgctt cctattattc
    30841 atcagttctg agtgaagtac ttcaaggatc tccgaccagt gactttttct gtctaatccg
    30901 tttgcttgca tccaatcaga aatagaagtg actttcccat tttgttcata agtcgataaa
    30961 tctatatttg gcactcgatc agaaaattca gcaggtaggc gcaaatcagg aatacgattt
    31021 acactactca tatgtgtttc tgcttgaagt tctttatttg tttgactatc tataaaatga
    31081 gtgatgacag tcgatgaagc agcagatgct tctacataaa ctacagctgt tgtttctgcc
    31141 acatttgatg ttttcgagtc tatataagtt aatacaacgg gatattctcc cggagttgta
    31201 gtatctactg tcccgttcat tttgatttct tctttatttc ctgaagttcc atcgcttttt
    31261 gttacatatt caacaagatc tttaggggcg taactctctc ctgttcttaa gtgaagatct
    31321 tttcctttga tagctgtttg atcagcacga acatggatca cagcagatgc agtcattgtt
    31381 tttaaagcaa ttggatcaaa ataggacaag gaaatagtag atgttcctgt attagtcgta
    31441 tccacgatat tcccattgtt tgaaattact ttggacatat ctccttgtgt tccatctgcg
    31501 ttcttcagcc tttctaccag atcagatatc gaaacttttg tccctgccag aacatcgatt
    31561 ttctttcttt caaactgtga ataatctttt tcatatacat aagaaacttg tgcgcttcca
    31621 ccgtccttta tatctgtcaa agcatgattc aaaatatcag tgatctgttt taactgatca
    31681 ccttttgtag gatcagtcat atcggaaaag atagaaagcg gcacactgct tccggtttcc
    31741 gatgtccata atgttttgtt aggaattaac cagtagtggt ttatcgttgg aggataactg
    31801 actttattat aggaagtcaa tgcaggaagt agctgttttc catttgcatc agtgaaagta
    31861 tgagtaatag tgatagggga atcagtggtc tcagaaacag aggtacgtac gaccttgatg
    31921 gtttgtgtcg ttgcctgaac gggtacatgc atatagacac ctacagataa actgatcagc
    31981 atcgtgcgca tcataaactt aacgtagtgt ttttcagaac acgaccgttc cttatctaaa
    32041 cgacaagcgt gtttatttag ttgttttgaa cgtctttttg aacacattta ttcttagtcc
    32101 tccctactct tgtctaaaca tgaagtagta attttcataa gatgatttca ttatataaat
    32161 aaaatcaaaa gaagatggac tattaggaga gtattttttt tgatttttta ttgtttcaag
    32221 aaaatcggaa taataactta tgtacttttt aattttgtta agtaatatat ctagttatat
    32281 ctagttatat ctagttacct tttctttgaa aaaaacataa atcagctaat aaatatgtga
    32341 gacaaagctg ccatccataa atactagctg attttttcag ttaaatgtct atttttttct
    32401 ctgatgatgg tatttccaaa atattcccag tcatctggag tcggtggatt tttccaaatt
    32461 atctgttctt tattaaattt ttcaagtaaa caatcagata aataaatatt cgtacgagaa
    32521 gtgattcgac tctcaatcac aatattgtaa tttttaaatc ctttcacttg agaaataatg
    32581 taatcggtat aagcagatcc ttgcgaaaaa tcaatacaga catgaatcgg tgcttcaaaa
    32641 tatgataccg gacaaatacc gaccaataaa aagagataat cataaaataa gcgaatcatg
    32701 aaacgttcat cttttcccaa gaaatagcgt ttattctctt gtatgacctt ttggattgct
    32761 gtactgaata ttggatacgt ctcgaagaaa aactgtagct gctttttaga cgtaaagcta
    32821 gtcatctcaa agtcgaatat ccaatttttt cgattgacat gcatcatacc catacgaagt
    32881 tcttttcgta tatatagtct ttcttcttca gagatttcaa tcgaaaatgg taattgatca
    32941 atcaattcca ctgacatttt ttgactaatc atgtggatat catgaaaatg agcttccgca
    33001 agtccaaatg cgccatctaa ttcaaattct tcttccgtga tcaaaaacaa catgatataa
    33061 gaaatctcat caatgatctg ctctttaggg atatgaagaa aagaaatatg tgataaatcc
    33121 ttgatgatct tcattccttc tgagctctta aagtattcat ctgaaaagaa acgttttccg
    33181 attggttgat tcccataggc cctcaacaaa ctaatagtgg ttagcaaatt gaatttgatt
    33241 cgttttgttg cagacagttt taaattgaac agatattcaa aatattgcac gatactcttt
    33301 gcttcattca tgacgctttc tctaaatggc atagaaaaac cattaaagac cccgaaatat
    33361 accccaaata atacgttccg tatgtttatt tcttccccaa ctaatatgtt tttctttaac
    33421 tttatttgat gctgttcaag aaaagagact aattctcttc tttttacata ggctcttgat
    33481 atgcttaaaa aatgattctc tgcaaatttt tcgatcgtta cttttgaatc cacgatctcc
    33541 gttaacagtc gagcaatttt tgatcgttga aagtagattc ttcttaaatt tttgatatcc
    33601 gtcaaattca gacgttcgac atggatctct gcttcttctg aaatttggat ctctggcttt
    33661 gttttgaatt cagtaaattc tttatttaat tctatgatat aatttcttgt tttaaattta
    33721 gacaaaccta atgtttcata taacttaggc agcactacat aattcttttt ctcaaattct
    33781 aaatatctag ctagcagcag tttttctcta tcttcctctt ctataaggta atccaacttc
    33841 atatcctaca cctcaaaaaa tgcctcatac caattacttg atatgcagat gaaagttcat
    33901 cttttcacct atactgattt tatgatggat tatgcttgtt ttttcatcag ttattctcat
    33961 tttttatctt ttttttgaga atattgcaaa aaatggaaaa atttatgagg aaatattcta
    34021 tattttttgt tttattgtgt taaaatgtac aagatttgcg ccatttgcgt aaacaaccac
    34081 aaaaaagagc aggacggcca ccgtcctgct cttttactta ttttaagttc cattacttat
    34141 taattggcta aacttctgct tgtttctgat attgcttgtt tttctccaat gatccgcact
    34201 tctgtttcta aagacacatc aaatttttct ttgattactt cttggatgtg cgcaatcaat
    34261 tcaatataat ctgtcgctgt cgcatgatcg atattgacga tgaatccagc atgtttttca
    34321 gagacttgtg caccgcccca tttcaggcct tgcaatcctg cttgttggat cagctgacct
    34381 gtatagtgtc ctactgggcg cttaaagaca cttccgcatg aagggtattc taatggctgt
    34441 tttgattgac gcaattcggt caactcatcc attcttgctt tgattgcttc ataatcccct
    34501 gtttgcaaac tgaatcgagc ttccaatacg atagcacgta attcttggac tttactgtga
    34561 cgataagaaa ataccatttc gtcttttgtc aaagttttca atgttccatc ttcaagcaaa
    34621 agatccactt cagcaaaaac atctttgatc tctccgccat acgcacctgc attcatataa
    34681 accgctccac cgacacttcc cgggatgccg caagcaaatt caaatccagt caatgattct
    34741 gccaaagctg cataagtcgt atcaatcagt gaggcacctg cttccgcaat gaccatcgtt
    34801 cctttgacat gaatctgttt catttcagtc agcatgatga ctacaccgcg aatcccgcca
    34861 tcttgaacga tcagattgct tgcatttcct aataccatcc aaggtatatc atggattcgg
    34921 caataatcga tgatttgctt tacttcttct tgttttttcg ggaatgcaag gacatcagct
    34981 ggtccacctg ttttcgtaaa cgtatagttc atcaatggtt catcaaacaa tatagtaatc
    35041 gtggctaagc tttcaactat ttcttcttta ttcactgagg attttccttt cttttctcaa
    35101 acgtcctcat tattctatca cgcttaatac aatcttgcca gtcttgttca aagttgatga
    35161 cggtagtgat ctttaagcac ttcctcacat aattcatgac ttcttacaac ttctttttgt
    35221 ttaagcaatt ctgtttccga tttacctaaa cggatctgag aaaagaaggc ctctaccatt
    35281 ggctcaaacc cgcgtttgac tagcgtgttt gtccagtcgc caaattcttt cacttttttt
    35341 ccatcagcat cttgaatgac aagctgggtc agatcgttta cttcataagt accattttta
    35401 cttgttactt gatatttttc tatattagcg ccacttgcta aatccatcgt taaaatagcc
    35461 gtttgatttt gtgtttctaa ttgtaaaatg gcatattcca aaaattcctt tgtttctctt
    35521 atctggtatt ttgttctcaa aatgggttca tctaataaat acacagctgt atcaataaga
    35581 tgtaaaaaca aatcataaag gacgaactct gtcgtttctt ttgccgctat tcgatttttt
    35641 tgcaggtgga tcaaccgctt atctgggata cgtttcaatt cttctaccat aggagcaaag
    35701 cgccggttga aaccgatcat caaaattatt tggttcttat cagctaattc ttgcaattca
    35761 cgaacttcat ttagatggac actcagtggt ttgtcaatat aaacatggat accattttct
    35821 agacattttt tggctaattc ataatgtact tttgttgctg cgtggatcat acatgcttcg
    35881 attttttctt ctaaaagctc atcgatcgtt tcatatagat gttggaaccc gtactctttt
    35941 tgaattcttt cttttgtttc tttatttctt gttgcaaaat aaaaatcaag tgttccttgt
    36001 tttttcgcat aagttggtaa atatgctttt tctgcgatat tccctacacc gattacacca
    36061 atcttcatct actttcctcc tggatcattt agttactttc atcttacacc attttttact
    36121 aaaatgaggt acaatagtat cgcaaaggta aggaaattaa ttcgaaggag tgtgctttta
    36181 ttgaaattta tctcttggaa cgtaaacggg cttcgtgcca tcgtaaataa aaatttttta
    36241 gaagtttttc atgagttaga cgccgatttt ttctgtctgc aggaaacgaa actccaagca
    36301 ggacaaattg atttagatct tccaggttat tatcaatatt ggaattacgc ggaacgaaaa
    36361 ggctattccg gcacagcgat ttttgctaaa aaaccagcat tgaatgccac ttacggaatg
    36421 ggtatcgata tccatgatac agaaggccgt ctgattactt tggaatattc cgatttcttt
    36481 cttgtaacct gttacacgcc aaattctcaa agcgaattaa aacgtttaga ttaccgatta
    36541 gaatgggaag aagcctttta taattatttg gaaaatctaa aaaaacaaaa accagtcatc
    36601 gtgtgtgggg atctaaatgt cgctcatcaa aagattgatt tgaaaaactg gaaaacgaat
    36661 caaaaaaatg ctggattcac tccagaagaa agagcggctc tttctcgact gttggataac
    36721 gggtttatcg atacattccg ttatttttac ccaacccagg aaggtgtcta ctcttggtgg
    36781 aactaccgat tcaattcaag gaaaaacaat gctggttggc ggatcgatta ctttttgacg
    36841 agcaaagatt tagagccagg actagctgat gcaaagatcc atacggacat tatgggcagt
    36901 gatcattgtc cagtagaatt agatttgaaa taaagaggtt gtgaaaaagt cgtttagttt
    36961 cgagtattaa gaaaaatttt gtgaaaatgg ctttccacat tttgcataaa tttggcataa
    37021 taccgagaaa ctggcttttg aacactgttt atcgagagat tgtgaaaaag ctgtcctgca
    37081 tcaagtaata agaacagcca aacaaaaata gttcctcata tttttcgttt ggttgggctt
    37141 attaccgcag atacaagctt ttgaacaccg tttattaaga ggttgtgaaa aagctgcact
    37201 gcatcaagta ataagaacag ccaaacaaaa atagttcctc atatttttcg tttggttggg
    37261 cttattaccg cagatgcaag cttttgaaca ccgtttatta agaggttgtg aaaaagctgc
    37321 actgcatcaa gtaataagaa cagccaaaca aaaatagttc ctcatatttt tcgtttggtt
    37381 ggacttatta ccgcagatgc aagcttttga acaccgttta ttgagaagtt gtgaaatcag
    37441 cgtcctgacc tgagtattag agaaacaaat ggcaaaatag ttcctcatat tttgctattt
    37501 tttgagctaa taccgagggt cagctgattg aacactgttt agtggagagg ttgtgaaatc
    37561 agcgtcctga cctgagtatt agagaaacaa atggcaaaat agttcctcat attttgctat
    37621 tttttgagct aataccgagg gtcagctgat tgaacaccgt ttagtggaga agttgtgaaa
    37681 aagtcgccta ctttcgagtc gtaagaaatt tttttgaaaa tggttcctca caactttgca
    37741 taaatttgac ttaataccga gaagtcatga tccccatcta actccaaatc acaaggaatg
    37801 agttcaaaaa ctagcttttc tcaacaaata ttacataaaa aattctatgt tttttgttaa
    37861 atttatttgc ttttttcaaa agtatgttac agtaatttcc caaggaggtt ttacagaaat
    37921 gaattttgtt gccatggatt ttgaaactgc caatcatcag ccttatagtg cttgttctct
    37981 tgcgctagtc atggtaaaaa atagccagat cgttgatgaa ttctatacat tgatacagcc
    38041 tgagactcct tttttctggc gaaatgtcca aattcacgga atccatcaag aagacgtacg
    38101 caatgcgccg aaattcccag aagtctggca aactatccaa ccatattttc aaaaaaatcg
    38161 tttagtcgtt gcacataatg ctgcttttga tacaaaggtc ttagcgggat gcttagatta
    38221 ttatcatctt gaacagccta attatctttc tttatgtaca gtgaaaagta gccgtcgcct
    38281 gtttcctgaa tttccaaatc atcgattgaa cactgtgtgc gaaaatttga acatccaatt
    38341 agatcatcac catgatgcat tggaagatag tcgtgcatgt gcggaaatcc tgctttatca
    38401 agaaaaaaaa ttcgggacag atccattgaa aaaacttgtg actataaagt aaaagaatac
    38461 ttatgaaaca cacaaagagg tcgtgagcct gccgtttcac tccgagtcac aaggagcaat
    38521 ttcaaaaaat agcttctcat gtttattaaa tattgtgact ggtgaccgag gagctggcag
    38581 gagaacaccg tttattggag aggttgtgaa aaagctgttc tgcatcaagt aataagaaca
    38641 gccaaacaaa aatagcttct catatttttc atttggttgg acttattacc gcagatgcaa
    38701 gcttttggac accgtttacc aagaggttgt gaaatcagcg ttttgacctg agtattagag
    38761 aaacaaacgg caaaatagtt cctcatattt tgccgttttt tgagctaata ccgaaggtca
    38821 gctgattgaa caccgtttat tcaaaaaaaa tggactgcga cacgactttt gtcacagtcc
    38881 cttcgtgtgt ttttctgcct tctcaaaagg atgacagttt ctcactcttt tcctatttct
    38941 tctattcaat caaataactc attttatata catctaaaaa ttcacctaga tctgttcttg
    39001 cccctctagg catgaccgct tcgatttgga agcccatttt tcggtaaagg tgtacggctc
    39061 tttcattacg aacttgaacg tcaagctcca atcgaaaaag tacacccatt tccttcgccc
    39121 aactgatgat ttcttctagc ataagagtgc ctagtcccat tccccaatat tcctgcagaa
    39181 tactgatacc gacttctccc acgtgagaca aacgaaattg actgtctgcc ttgacagatg
    39241 ctgttccaat aatcgtccct tcatagattg caagcagcaa taaattatta ttgctttcgt
    39301 atatataatc caactcttct tctaaggttt ctggtggtaa caggagttct gcttcatcca
    39361 aaactaaaaa ttctgtctcc ttattaactt gtcccatcat caaaagaatg tcttttgcat
    39421 ctcctggcac tgcttcccgc aagatgatcc caacttcttc actcatgatt ttcagcccat
    39481 ttttctagaa ttcgctgttt gaaggtttca ctttgctccc cgtatgagat tagtttcaca
    39541 taccgctttt ctaaatctgt atcacttttt tctaaaatca gttccaaata atcctccggc
    39601 agtgcttctt ctaatagatt tccccattca acaacggaaa gcccatcacc ttcaaaatat
    39661 tcatctaacc ctaaatctgc tccgctagct gctacccgat aaatatccat atgatacaac
    39721 ggaatccgac cttgactata ttctctaata atcgtgtatg tcggactttt gatcatttgc
    39781 gttatcccta atccttgggc aattcctttc gtcaacgttg ttttacccgc acctagatca
    39841 ccagtcaata tcagattgtc acctggcatt gcggaatgac caattgcctc tgcgaattgt
    39901 tctgtcattg ttaatcctga tagttcgatc atttttcatc ttctcccgct cttctttctt
    39961 tttgccagta tatcgcgtaa tgaagttttt ttaaagaaaa aatgaactag tcaagaacag
    40021 cagctgctgt ttttggctag ttcgcgtgta tttgttaatc aatcaatgtt tgtgctgctg
    40081 tgataatcga taatttatat acatcttctt catttgctcc acgagacaaa tcagaaaccg
    40141 gtttgttcaa gccttgtaga attggtccga ttgcttcaaa gttaccgaaa cgctgagcaa
    40201 ttttatagcc gatatttcct gactgcaatt ctggaaatac aaagactgtt gcttgaccag
    40261 ctacttctga atctggcgct ttcagttgtg caactgaagg aacataagaa gcatcaaatt
    40321 gcaattcgcc gtcgatcatg tattgtggcg ctagtttttt agcgatttta gttgcttcaa
    40381 ctactttgtc tacttctggc gatttcgctg agccttttgt cgagaagctc atcattgcta
    40441 cttttggttc gatatcgaac aattctgctg tttttgcaga atctacggcg atttcagcca
    40501 attcttgcgc agttggattc acgttgatcg cacaatccga aaagacatat ttttcttgat
    40561 ctcttccacg taccatgatc atcgctccgc ttgtccgact gatgccaggc tttgttttga
    40621 tgatctgaag tgctgggcga acagtgtcgc cagtcgaatg gatcgctcca gagaccattc
    40681 cgtctgcaat ccccatatac gtaagcatcg taccaaagta attcacatct tttaaaatct
    40741 tttctgcttg ttctttggat gcctttccat ttctacgttc aacaaaagta tccaccattt
    40801 catcccactt atcgtaatta tcagggctga tgatcgtaaa gctagatgtt ttgattcctc
    40861 tggcatgcgc tgcatttctt atttcttctt cgttccctac taaaatgggt tccacaagtt
    40921 cttctgcttt caaccgggca gctgcgccta aaatacgagc atcagtagct tccgggaaaa
    40981 cgattttgat cccacggcga acaattttaa atcttaaact atcaaacaat tccacaagat
    41041 gacctccaga cgtttttata tgtattatca tacactattc cagaaaaaaa gaacagttta
    41101 ttttatctgt atcagtcaaa aatgctggaa aaattaagtt tttcacatac aaagcgaact
    41161 gcactataac aggaaagcgc tgttttatta cactgtttca ggcagttgcc aatcaatcgg
    41221 ttcttctcct aacgcaagga gcgcatcatt cgttttcgag aagggtttgg aaccaaaaaa
    41281 gccacgactt gcagataacg gactgggatg tggagatgtt atgatgatat ggcgactctt
    41341 atcgatcatt ttgatttttt cttgtgccgg ttttccccac aagataaaca cgattggttt
    41401 ttcccgttca tttaattttt caatgatcgt gtctgttaat ctttcccaac ctttcccgcg
    41461 atgagaatac gcttgccctt cccgaacggt aagaacggtg ttgagtaaaa ggactccctg
    41521 tttagcccat gacactagat ttccatgttg aacaggtgcg attccaagat catcataaag
    41581 ctctttatag atatttctta acgatggcgg gatctttacg ccaggttgca cagaaaaaga
    41641 taagccatga gcttgatttt ctccatgata aggatcttgt cctaaaatca ccactttaac
    41701 ttcttcataa ggagtcaatt ccaatgcttc atagatatga tacatatctg gatggatctt
    41761 ttgggacgca tattcttttt ttaaaaattc tcttagatgc agataataat cttttgaaaa
    41821 ttctgaggac aaaacttctt gccaactgtt atgaatgatt tctttcaaaa actccacctc
    41881 ctaataaaaa gaataactca cattttcttc aatcacaagg gacaatcttc accctcagca
    41941 cttgattaat atggtaaact aggaacaaga agcagaaagg aacgataatc attatgatca
    42001 aattaattgc atcagatatg gacggcacat tattagatgc ccatatgagt gtttctcctg
    42061 aaaatgccga ggcgatacgt tttgcaaatg atgccggtgt tgagttcatg gtcgctactg
    42121 gtcgaaacta tcaagaagct cgcgcagctt tagatgaggt aggaatcgat tgtgcgatga
    42181 tcactttgaa cggggcacag gtatttgata aagaaggaaa ttcattgttt accgtgtcga
    42241 ttccaaataa tcaagcaatc tctgttttag atattctaga tgctaacggt atttactatg
    42301 aagtagcaac caacgatggt ctttattctg aaaatcaagc gaaacgaatt gaaagttttg
    42361 cttccatggt ggctacccat ttacctcacc ttacgtataa aatggcgatt gccatggcct
    42421 cagctaagct ggagttattg cacatcacat acgtggacag tattcgtgct attttggaag
    42481 aaaagaatct ggaagtttta aaaattattt gttttcatac agaagggcca gctgtattag
    42541 gtccagttgg aaagcagatt tctcttttag gcgatctagc cgttacttcc tctggtcaaa
    42601 acaatatcga agtgaaccat aaaaacgctc aaaaaggaat tgctgttgcc catgtcgctc
    42661 acgagcgtgg gatttcttta gaagaagtca tgacgattgg cgataacttc aatgatgtca
    42721 gcatgctgca agtagcagga gtcagtttcg caatgggaaa tgcagaaatc gaagtaaaag
    42781 attatgccaa atatacaacg gacacaaacc ttgaatctgg cgtaggaaaa gccatattgc
    42841 gcgcgattgc agaagacttg tagttttatc tagaaaagag ggatatagat gtcagaattt
    42901 ttcattcagg aaaagcagct tggacgtgca actcggacaa ttgtcaaaaa cgaaaaagga
    42961 cattccctgt ttttgatggt tggtcgctgg ggaacaaagg gcgatgcatt gtctctttat
    43021 gccatgaatg gcgatctcgt tgctcacatc aagcagataa gcctgacatt cggtacgcgt
    43081 tttgagctgt ataaagagtt cgaaaaggtg ggaaccatgc agaaaatatt caattggccc
    43141 ggtgactttt attatattcg tagacttcac tggacagtcc aaggtgatat ctataatcat
    43201 caatatcaaa tccatcattt caatcagcaa atcatgaaaa tggataaagc aacacttttt
    43261 tcaggagatt actatgtatt ggatgtctca aatgatgaag atgctccagt ttgtatttgt
    43321 attgctgcgg ttttagatta ctggctctac cgtaaagaca aaagtcgcga taagcctgtt
    43381 tcttaccgac ttaacttaag ttaaaaagat gtacctgaaa tgcggaaata cgcatttcag
    43441 gtacatcttt t
//
LOCUS       DAYNVV010000016        42489 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.016, whole genome shotgun sequence.
ACCESSION   DAYNVV010000016 DAYNVV010000000
VERSION     DAYNVV010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42489
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.016"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            333..740
                     /locus_tag="ACGXWR_001045"
     CDS             333..740
                     /locus_tag="ACGXWR_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802644.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            754..1155
                     /locus_tag="ACGXWR_001046"
     CDS             754..1155
                     /locus_tag="ACGXWR_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802645.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1157..1528
                     /locus_tag="ACGXWR_001047"
     CDS             1157..1528
                     /locus_tag="ACGXWR_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802646.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1564..1866)
                     /locus_tag="ACGXWR_001048"
     CDS             complement(1564..1866)
                     /locus_tag="ACGXWR_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFK0802647.1"
                     /translation="MLMEGKTQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2124..2237)
                     /locus_tag="ACGXWR_001049"
                     /pseudo
     CDS             complement(2124..2237)
                     /locus_tag="ACGXWR_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(2620..3852)
                     /locus_tag="ACGXWR_001050"
     CDS             complement(2620..3852)
                     /locus_tag="ACGXWR_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HFK0802648.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            4106..4675
                     /locus_tag="ACGXWR_001051"
     CDS             4106..4675
                     /locus_tag="ACGXWR_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFK0802649.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(4853..5293)
                     /locus_tag="ACGXWR_001052"
     CDS             complement(4853..5293)
                     /locus_tag="ACGXWR_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HFK0802650.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            5451..6215
                     /gene="map"
                     /locus_tag="ACGXWR_001053"
     CDS             5451..6215
                     /gene="map"
                     /locus_tag="ACGXWR_001053"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFK0802651.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            6247..7170
                     /locus_tag="ACGXWR_001054"
     CDS             6247..7170
                     /locus_tag="ACGXWR_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HFK0802652.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            7246..8385
                     /locus_tag="ACGXWR_001055"
     CDS             7246..8385
                     /locus_tag="ACGXWR_001055"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HFK0802653.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            8378..9178
                     /locus_tag="ACGXWR_001056"
     CDS             8378..9178
                     /locus_tag="ACGXWR_001056"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFK0802654.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            9178..10005
                     /locus_tag="ACGXWR_001057"
     CDS             9178..10005
                     /locus_tag="ACGXWR_001057"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFK0802655.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            10010..10717
                     /locus_tag="ACGXWR_001058"
     CDS             10010..10717
                     /locus_tag="ACGXWR_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFK0802656.1"
                     /translation="MRSVCIATFNGGRYLREQLDSILSQLSAEDEVVISDDGSVDDTW
                     DILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWLETKVKKITD
                     YFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYIGAGMAFRSS
                     LKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIETHSKLRQKIS
                     WRVHLITALIKRKWFKR"
     gene            10817..11683
                     /gene="rfbA"
                     /locus_tag="ACGXWR_001059"
     CDS             10817..11683
                     /gene="rfbA"
                     /locus_tag="ACGXWR_001059"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFK0802657.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            11697..12269
                     /gene="rfbC"
                     /locus_tag="ACGXWR_001060"
     CDS             11697..12269
                     /gene="rfbC"
                     /locus_tag="ACGXWR_001060"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HFK0802658.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            12291..13319
                     /gene="rfbB"
                     /locus_tag="ACGXWR_001061"
     CDS             12291..13319
                     /gene="rfbB"
                     /locus_tag="ACGXWR_001061"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFK0802659.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            13417..14268
                     /gene="rfbD"
                     /locus_tag="ACGXWR_001062"
     CDS             13417..14268
                     /gene="rfbD"
                     /locus_tag="ACGXWR_001062"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFK0802660.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            14303..16336
                     /locus_tag="ACGXWR_001063"
     CDS             14303..16336
                     /locus_tag="ACGXWR_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802661.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMITFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            16380..17660
                     /locus_tag="ACGXWR_001064"
     CDS             16380..17660
                     /locus_tag="ACGXWR_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HFK0802662.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYRWVPIIYILLAMAVHRYDEPEVTEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            17870..18676
                     /locus_tag="ACGXWR_001065"
     CDS             17870..18676
                     /locus_tag="ACGXWR_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0802663.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            18688..19908
                     /locus_tag="ACGXWR_001066"
     CDS             18688..19908
                     /locus_tag="ACGXWR_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802664.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGKVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            19898..21484
                     /locus_tag="ACGXWR_001067"
     CDS             19898..21484
                     /locus_tag="ACGXWR_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFK0802665.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLYINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAQPQNSNYVKVLEVIQQTKQDEIIQQIPFNNFTGENETLSFHVSELA
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKDLPEFFLTDIAG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHYLIENNTRLD
                     QTLKTTINRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSLCIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVLREEVNQAKQLAEGAKAGFELRILCEK
                     ERSFLVEAVAQNGQSWIIEM"
     gene            21523..23661
                     /locus_tag="ACGXWR_001068"
     CDS             21523..23661
                     /locus_tag="ACGXWR_001068"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFK0802666.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEVQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALEMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPAEHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVHPGRISGFYEITYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(24029..25012)
                     /locus_tag="ACGXWR_001069"
     CDS             complement(24029..25012)
                     /locus_tag="ACGXWR_001069"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFK0802667.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            25390..26781
                     /locus_tag="ACGXWR_001070"
     CDS             25390..26781
                     /locus_tag="ACGXWR_001070"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFK0802668.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            26797..27837
                     /locus_tag="ACGXWR_001071"
     CDS             26797..27837
                     /locus_tag="ACGXWR_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFK0802669.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRKIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            27856..28941
                     /locus_tag="ACGXWR_001072"
     CDS             27856..28941
                     /locus_tag="ACGXWR_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HFK0802670.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            28974..29936
                     /locus_tag="ACGXWR_001073"
     CDS             28974..29936
                     /locus_tag="ACGXWR_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HFK0802671.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            29929..31356
                     /locus_tag="ACGXWR_001074"
     CDS             29929..31356
                     /locus_tag="ACGXWR_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HFK0802672.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            31358..32428
                     /locus_tag="ACGXWR_001075"
     CDS             31358..32428
                     /locus_tag="ACGXWR_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysialyltransferase family
                     glycosyltransferase"
                     /protein_id="HFK0802673.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            32415..33836
                     /locus_tag="ACGXWR_001076"
     CDS             32415..33836
                     /locus_tag="ACGXWR_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFK0802674.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            33849..34856
                     /locus_tag="ACGXWR_001077"
     CDS             33849..34856
                     /locus_tag="ACGXWR_001077"
                     /EC_number="4.2.1.115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050377 - UDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4,6-dehydratase family
                     protein"
                     /protein_id="HFK0802675.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            34868..35872
                     /gene="neuB"
                     /locus_tag="ACGXWR_001078"
     CDS             34868..35872
                     /gene="neuB"
                     /locus_tag="ACGXWR_001078"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0016051 - carbohydrate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HFK0802676.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            35869..37017
                     /gene="neuC"
                     /locus_tag="ACGXWR_001079"
     CDS             35869..37017
                     /gene="neuC"
                     /locus_tag="ACGXWR_001079"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0006047 - UDP-N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HFK0802677.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            36990..37667
                     /locus_tag="ACGXWR_001080"
     CDS             36990..37667
                     /locus_tag="ACGXWR_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HFK0802678.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            37618..38799
                     /locus_tag="ACGXWR_001081"
     CDS             37618..38799
                     /locus_tag="ACGXWR_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFK0802679.1"
                     /translation="MAIQLKLRKKELILNSRILLSSPHMGGTEEKYVAKAFKDNWIAP
                     LGENVDKFEESITKYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATV
                     NPILYQGAVPVFIDSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYER
                     ILAIANQFNVPVIEDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSD
                     KKYVEHSRFLATQARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIF
                     NRYKEAFSGIDRIEMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRA
                     LWKPLHLQPVFQGVKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIF
                     K"
     gene            38812..39789
                     /locus_tag="ACGXWR_001082"
     CDS             38812..39789
                     /locus_tag="ACGXWR_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFK0802680.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            39789..40697
                     /locus_tag="ACGXWR_001083"
     CDS             39789..40697
                     /locus_tag="ACGXWR_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HFK0802681.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            40698..41450
                     /locus_tag="ACGXWR_001084"
     CDS             40698..41450
                     /locus_tag="ACGXWR_001084"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HFK0802682.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            41455..42402
                     /locus_tag="ACGXWR_001085"
     CDS             41455..42402
                     /locus_tag="ACGXWR_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFK0802683.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT        14263 a         6436 c         8218 g        13572 t
ORIGIN      
        1 cttttaatta gatttctagt ctaacttttg gggtgcacat catttttgag gggaagtaca
       61 tatagttgtt gatatagttg ctaatattgt tagctaattt gttagtaaaa ctgtatacga
      121 atttagatag taaaaaaaca gtttgttcct tatatagagg cacttttact actgattaaa
      181 tgtcagatat gcttacaaat atacttataa atatgcttac aaaattagct aatatttccg
      241 ttgacaaagc tttgttacta ttgttaaact aaattgacta gcaaaagtga aacataaatt
      301 tattaaataa atgtaaaaat taggagaaat caatgtctta tagagtacaa ttaataattt
      361 cagaagatgt agaaagtcag caatttggca ctaatgttat taataaagta attaatccag
      421 ctctttctat taatgcgcct ttaattccta ctgctttatc attttctgta acagctgtgg
      481 tgtctgagat agaggataca gaaaagataa aaatagtaga aattgaagtt ttaaacaaga
      541 atgaaaaaca aattttttct acgggtgaag tatcggtaag cttgcctcct caagttaacg
      601 atataaactt taatataaac gccagaaatg tcttggttga agaagcagga gagcattatg
      661 ctgttgttaa atttaatgga actgagattg gaaggcaaat ctttgatatc aaggtcaaca
      721 aaccagtgga aaaaaattaa ggagacgata cggatgcttg atatagtacc atcaaataca
      781 catcggagtg gtagcttaat aaattttgct gcgatttttg cttgcgcatc ggtaattcta
      841 gcatctccag ttgttgtgga tgcaagttct actccgaaaa ctaaaaatga taatcaactt
      901 gtaattacta caaaaaatga gattaacaca atttcaagta atgatggcaa aatttttgat
      961 gtgataaata cggttttaaa aagaaaagct gaaatcaata taaaatatga tgaagattta
     1021 aacttgtatt tctttgttat caaaacaaca tctgaattgt tttcctcaga ttacgatgtt
     1081 ttggatactc tcgataatgt attatctgac tataaatata tggggaaatc tgtagtagca
     1141 actttggggg aataaaatgt ttgactttaa tgaatattta tctatttcca aacaaattga
     1201 atcagatgat aaatataatt ctaaagaatc ttatagaaga actgctgttt caagagcata
     1261 ctacagtgct tttaaaaaat ctgatgagta tttgaaagaa aattatgata ttatttataa
     1321 tggaagtagc ggaaaaggaa gccaccaaac cgtttggaat ttgttttcaa cagttaagga
     1381 attgaatacc ttaggaatac ataatagtgg gtatagaatg ttagagaaaa gaaaatgtgc
     1441 tgactatatt cctaatgaaa ccattacgaa aacagatatg gcgctgatga atcgagaagc
     1501 agaaaaaata ataaacaaac tcacctaatg aatttcaagc gagtttgttt gttatttttt
     1561 tatttaatct ttgtatcttt ctggatcaac gaaagtatac tttatatagt cataacgccg
     1621 atgatcgcta cgtgcgtccg gcacgtcagt cacgatatca aacaaaaagt atacaccctt
     1681 cttcattcta gttttcgcag caggaatttt gaaatagttc ttattagaat agtagagatt
     1741 gattaataag ctatcttcga ttgctaaaaa gaaaacttct gaattccata ctttataaaa
     1801 atctttgata aatctattcg aagggtcaaa tttaaaccat aattgtgttt ttccttccat
     1861 cagcataaaa gttcacctca aaaagagtat acgaacgaat gttctttttg tgaaggcgga
     1921 atttaatata ctgaataata gaaaacaagt acttgtgcca aattatgtgc caaaaaaatt
     1981 cgaattcaac aaaatgtaaa caaatagaaa accttctata ttaagatttc ctgcaataac
     2041 aaacacaaca gaagacgtgt aatagttagt caggaacgta caaataaccc ctgtatcctt
     2101 tgcggtacag ggggttattt tgtataagta gacattgtag tttctaaact gctatgtcct
     2161 aaacgtttcg atacgctaag tatatttact ccttgataaa gtaaaataga tgcatgcgta
     2221 tgtcttagtc catcaataaa cagtcgaaga gaaaataggg aaaaattgat tactaaagaa
     2281 aaacttacta ggtcgacggt gtagttgatt ttcatacttc aatagattcg aattaaacga
     2341 tttcgattgg cttataccag tcctatccaa cgaaagatat atcgttctta actctagcgg
     2401 tataacttga agctttacgt aaagccaatg ggaatgaact ggagatgact ttttattatt
     2461 tttagtaata gctgatgggt taatacttac aactttcctt ttcaaagtac catataaaaa
     2521 aacggtgggg ttgtttagcg aaataaagga tctaagccaa tagcttagat cctttattct
     2581 atgctttata ttattttttg catgtgtgcg aaagtatact caagcccaat cgccgtttcg
     2641 gaaaatcggt actgtagagc catcttcacg gattccgtcg atatccatct tgtcagatcc
     2701 taccatgaaa tctacgtggg tttgacttct attcaatcca gcttctgcta attcttcatc
     2761 ggacatttct gtaccgcctt tcacactgaa ggcataagca gaacctagtg ctaagtgatt
     2821 cgatgcgttt tcatcaaata atgtattgaa aaagatgatg ccagattgag aaataggtga
     2881 agggtcaggt acaagtgcga cttctcctaa acgacgcgca ccttcatctg tatcaagcag
     2941 ttttgctaag acatcttctc cttgttcggc agaaaaatca acaacttttc catctttaaa
     3001 agtaaatttc atacccgaga tgatggtgcc agcataactc agtggctttg tacttgaaat
     3061 gtaaccatct actcgatgac tgtcaggtgc tgtgaacact tcttccgtcg gcatatttgc
     3121 catgaatttt tctccacgag cattatagct tccagcgcct tcccaaagat ggtttttagg
     3181 caatccgata atgatatctg taccgggagc agtatagtga agggcagaaa attgttctcg
     3241 attcaattct tctgcttttt ttgctaattt ttcatcatgc ttcttccatg ctaagacagg
     3301 gtcttcttca tagacacgag tcgttttgaa aatctgatcc cataatgcct caacttgttt
     3361 ttcttctggc agttctggga agacttttgc tgcccattgt ttaccagccg cagccacgac
     3421 agtccaactg actttatttg cttgagttgc cttgcgtaaa ttcattagtg ctttgccatt
     3481 cgctgattga taagacgcta ctcgatggct atctacacca gcaaatgcat cgggatcggc
     3541 agaaacaacg ctgatcctgc ttgctccttt ttcaagccat tcatccgctt gatcgatttt
     3601 agattgtggt acattctcaa tacgatccgt tgcagcatgt aaaagaaatt ctctttggat
     3661 ctggtcgtca gtccattgaa cgataacctc agcggctcct agtttataag cttcttgtgt
     3721 gatcaatcga gcaaggggtg cctgttccac gctgatctgt aaaacaactg tgtgtccttt
     3781 ttctgtggct acgccagttt ctgcaattaa gcgtgcatat ttttttagaa gttcattaaa
     3841 atcagataac ataataaaaa ttcctcctca ccattttttc tggtaactat tagcatgata
     3901 ccatttaatt atgattcaaa caatgaggct ttaaataaaa aaaggaggtt atttttttaa
     3961 ggttaagttt catgatatat gttactactt gctatttcag cttgtgaaga aaatcaaaaa
     4021 ctaattttgc atatcaaaaa aacatgttac aatgaaatta atcaatggtg gaagcgttat
     4081 aaaaaaatta aggagattaa aaaatatggc aagaaaaaag acgattacta gagaacagat
     4141 tttggcagct gcttatgaag tagctgccac cgatggattt acacgattta ctgcgagaaa
     4201 catcgcgaac aaaatgaatt gttccacgca accgatttat cttgagttta aaaatatgga
     4261 tgacttgaga caagctcttt ttgagcagat ctatgatcat ttacaatatg aagtgttcac
     4321 tgttgagcat acagggaata cgattatcga tcttgctttt aattatatcc attttgcaag
     4381 aagagagaag aagttgtatc gttcactgta cttagaagaa tatggtggag gaaaagagat
     4441 gcagaatttc tcttatactt actttgtgaa tacagtgaaa cgcgatccag cttatgtgaa
     4501 tctttcagaa gagcagatcg aatctttgta taatgggaca tggatcatag ctactgggat
     4561 cgcagctttg atgtcttcaa gcatcatcca tccaactgat gaacagattg aaaagatgat
     4621 ccaagacagt atagatgcta tcttgaaatt caaagaacca atcgaaatcg attgaatata
     4681 ctcaaaagtt ccacaaatca gtaggtaaca agagatgtgt caaaataagg aaaagttcgt
     4741 ttttcttaca gcgtatgcat ttttaactcc cgaagaactc ttccatgaat gcaatgaata
     4801 aaagagccat acagattgaa taaatctgga tggctctttt attgcaagta tattaaattt
     4861 ttgcgactag ttctttagcg aaagcttcta aattttcgat atcttcttct tcagcattca
     4921 gatccacttt aacattttcg gctccttttg atgcgcctgt ttttgcaaaa gcagcatcga
     4981 aatcatccac cgatttgcag aattcatcgt aaaaagtatc accagatccg cagacaccgt
     5041 aaatttttcc caatagatcc aattcttgca agtcttcata aaagtctacg atctcatcag
     5101 gcagatcgcc atcatcgtat gtataagtag ctactacgca aatatctgcc tcctcgaatt
     5161 catctgcatc tacttgggta cattcgttga tttcgacttc gatatccaga ttttcaaatg
     5221 cttctgcaac aatatcggcg atttcttcag tgtttcctgt catgctagca tatacgattt
     5281 ttgctaaagc catgatgtgc ctcctcgttt ataattattt aacaattatg aattatacca
     5341 aaacatcatt gaaaagaaaa taaaacctaa agacacctgg ggaatgtcat ttggctaaat
     5401 gtatgccgct atgttaaaat gagagggatt tgtaaaaagg agacgaaaat atgattactt
     5461 taaaatcagc acgtgaaatt gaaatgatgg cagaatctgg agctttatta gcagatgtac
     5521 ataaaaatct gcgtgatttt ataaaaccag gaatcacaag ttgggatatt gaggtatttg
     5581 tcagaaacta tatcgagagt catggcggaa ttgctgcgca aattggcttt gaagggtatg
     5641 aatatgcgac ttgtatcagt ataaatgatg aaatttgtca tggattccct cgtaaaaagc
     5701 ctttgaaaaa cggtgatttg gtaaaagtcg atatgtgtat cgatttgaaa ggcggcattt
     5761 ctgattcttg ttgggcctat gtagttggag aatctacacc tgagatcgac cgattgatgg
     5821 aagtaacgaa gaaagctttg tacatcggta ttgagcaagc acaagtaggg aatcggattg
     5881 gtgacatcgg tcatgctatc caaacttatg tagaaggcga aaatctagcg atcgttcgtg
     5941 attttattgg tcatggcgtt ggtcctacga ttcatgaaga accagcagtt cctcattacg
     6001 gagaagctgg aaaagggttg cggttgaaag aaggcatggt tatcacgatc gaacctatgg
     6061 ttaataccgg aacttggaaa atgaaaatgg atcctaacgg ctggactgcg tatacaagag
     6121 acggcggact ttcttgccaa tatgaacata cattggctat tactaaagat ggtccaagaa
     6181 ttttgacatc acaaggagaa gaaggcactt attgatctat ccagtcaata ggtacgggag
     6241 aggtacatga aagtttggaa caaaataaaa caaaatgaaa atctgatgcg ctttattgag
     6301 acgactcaaa agcgcatcac tgattcagaa atgagtacga cctctgtcgt cgttgcttat
     6361 tatttactct tgtctttatt tccattgatt attgcttttg gtaatatttt accgtttctc
     6421 cacatcgatc aagagactgt actgacctat ttacgagaag tgattcctga gaccgtttac
     6481 cagtttatcg gtcctgcaat caaagacctt ttgacacaaa gttcaggagg cttgttatcc
     6541 gtttctgcat tagcggcttt atggtctgca agtcaaagta tcaatgcttt gcaaattgcg
     6601 atgaataaag cgtatggcgt agaaaataga aaaaattttt tgatcgtccg tttcttctca
     6661 ctaattgtca ttgtcttgtt catgattgct attagtgggg taactatcgt tcttgggttg
     6721 ggacagctga ttttggatgc tattcagcca atcgtacaaa tacccgtgaa ctttatcgat
     6781 cagttccaaa ctttgaagtg gccaatcaca ttggtagctt tatttgtcat catgttcttg
     6841 atttatttaa ttgtccctaa tgctcagttg aagttgaaga cgatcattcc gggcacgatc
     6901 ttcgctactg tcggctggat gctgttatca caagtgttta gtatctatgc taggtatttt
     6961 gcaacgagga tcagcggtta tcagatcata ggaagtttta ttgtactcat gctttggctt
     7021 aattttgctg ctacgatcat cattttgggc ggaatcatca atgcagttgt tcaagaatac
     7081 gtgacgggtc atcaaatcaa aaaacgtcga gatccaagcc gaaaatggtt caataaattg
     7141 aaaactaaat tttctcataa aaaaaagtag aaacaagagt tcttattgta aatttatatc
     7201 agtaatttat aataattatg actcttaatt aaagtaggtg cccatatgct tgtttctttt
     7261 agtatggtta taagattttt tctgacaatt ttattatcac tgatattaac acctgtattc
     7321 aaaatcattt cagtacaaac aggtatggtc gacaaaccaa atgaaagaag aataaataaa
     7381 gttccaatgc cttcagcggg cggactgcct atctttattt catttgttat atcgacttta
     7441 ttcttattcc gtaaaattat ccctcaatcg tatattgtac cgatcttgat tgcttcttta
     7501 gtaatcatag tcacaggagt gctcgatgat aaatatgagc tgacacctaa acaaaaaagt
     7561 atagggatct tgattgcttc tcttattatt tattttgtag cagatatacg tattgattcc
     7621 ttcacgcttc cttttattgg atatatccaa ctaggctggc ttagttttcc cgtaacgatt
     7681 ttttggatct tcggtatcac gaatgcggtc aatctgattg acggtttgga tgggctggcg
     7741 gcagggattt cattgatcgg tttaattacg ataggaatca ttggatattt tttcctccat
     7801 gcttctacag tgtatattcc agttgttatt ttctgtcttg tagcaagtat tatcggtttt
     7861 tttccttaca atttttatcc ggcaaagatt tatttaggcg atacaggagc tctattccta
     7921 gggtttatga tggccgtcct ttcactacaa gggctgaaga acgtgacttt tgtttcatcg
     7981 atttctttgc tgatcgtcat gggagtgccg gtaacagaca cgttttttgc tatcattagg
     8041 agaaaagcaa accgtgtttc tttttctaca gcagataaaa aacatcttca tcaccgacta
     8101 atcagtttag gctttactca taaaggtgct gtcctgacga tttatgcgat ggctttgatg
     8161 ttttctttca cagctatggt catgaattat actggaagaa tcggaacgat catattgatt
     8221 attgccatgt tgtttgctgc aattttatta tttgaattga ttggtctgat caatgagaaa
     8281 catcagttta ttttaaaaac attgcgattt ttagggaata aagagtaccg tacgcaagta
     8341 aaacagaaat atttgaagaa atggaaccgt catatagatg aataacaaat taaaccagcc
     8401 gatccttatt agtattgtga cggcaaacag tgataaaatt tttcggacac tagataattt
     8461 tatttcaact gtaaaagatg aaacagcagt aaaaatccga atttttgaca acaattcact
     8521 tcccgagtac aaaaaaagac taacagagta taggaaatat ccctacatcg atatctattt
     8581 tcatgatgaa aattccggat ttggttatgg acataatcac aatctgatag ctagcgattc
     8641 tcgctatggc attatttgta acccagatat tttagtggat gaagagacag ttacagcatt
     8701 ggtcttgtta ttgaaagaac atccggaatg tgcgatgtta gcacctaaga ttcttaatga
     8761 agatggaaca actcagcacc tcatccgtga gcagctggct gtttttgatt acgttttgcg
     8821 ctttgtgcct ttcaaatggg tcaaaaaaaa gtttgacaaa cgactggctg tgtttgaatg
     8881 ccgaggattg cctactgatg ctaatagtta tgtacggatg atctcaggta gttttatggt
     8941 agctgatatt gataaattta aagagataaa ggggtttgat gagcgtttct tcatgtactt
     9001 tgaagacaac gacttgtgtt tgagttttga aaaagcaggt tacaagttat tgtacacacc
     9061 cttttatgca gttatccatt tttacgggaa gggtgcgcat cgaaatgcaa aactgtttcg
     9121 cgtgtttttg acttctatga tgaaattttt caataagtgg gggtggcgtt ttttctgatg
     9181 aaaccagaaa tattagtagt cgttgtgctt tatcagcaac tattcagtca atctccagct
     9241 tatggaccat taagcaaagc acttagcgaa aagcaaattc agcttattat ttacgataat
     9301 agtcctcaaa ggcagcaaaa tgagctgttt gaaaaagaaa atatcgttta tcatcatgat
     9361 ccgcaaaatc ctggtttagc ggtggcttat aattttgcgt tgtctcaagc agatgaagga
     9421 acacgttgtc tcgtcactct ggatcaggat acgaggctag tcgacgatta ttttgaacta
     9481 ttgcgtaaag taacctttac agatgaatgt gttgctgcag ttccgatgat tttttctggg
     9541 agccgacaag tttctcccct atattcagat cgttatatca atcgtacagc tcaagcagta
     9601 gaagttgaag gcccaacagc tgaacgaatc atggcaatca attcaggtgt tgcctggtct
     9661 gtcaaatttc taaaaaagat tggcgggttt aatcctgctt tttctttaga ttttttggat
     9721 cattggctgt tttggaaagt ggatcagttg gaaaaaactg tggagatcct tcctgtacga
     9781 atggaacatg atctttcggt tttagactat gaaaaagttt caagtaatcg ataccgttct
     9841 attttacaag cagaaaatcg attttatcat gaatatgatc aaaggcattt atccagtcac
     9901 cgacgacaat tattgttaag aacagctaaa cagttcttga ccgtcaaaaa ccggcatatc
     9961 tggcggatga ctttgcgctc atatgttaag aattggaagg tgtgaattcg tgcgttcggt
    10021 ttgtatagct acctttaatg gaggcagata tttaagagag cagttagata gtattttatc
    10081 tcagctttca gcagaagatg aagtagtcat ttctgatgat gggtcagtag atgatacatg
    10141 ggatatatta actgaatacg cagaaaaaga taagcgaatc cagctttttt cggggcctcg
    10201 tcaaggattg atcgctaatt ttggttatgc gatccagcag acgaaaggag atctaatctt
    10261 tttggcagac caagatgatg tttggttgga gacaaaagtg aaaaagatca ctgactattt
    10321 tgagcagaat ccggatcagc tagtagtagt ttctgattta atcattgtgg acagcgagct
    10381 gcaagagatc catgattcgt atttttcgtt tcgaaattcc aaagaaggat ggcttaataa
    10441 tgtgataaga agtcactata ttggtgctgg tatggctttc cggtcttctt taaaacccga
    10501 tattttgccg atcccgtcag aagtgccgat gcatgatatg tggattggtt tgctgggagg
    10561 aaagaagact gggttcctaa gagaaccgtt aactctgtac cgaagacatg atttaaacgc
    10621 gagtgagatt gaaacacatt ctaaattacg gcaaaaaatt tcttggcgtg ttcatctgat
    10681 tacggcgttg atcaaacgaa aatggtttaa acgttgataa aagatgttta aatccttaat
    10741 atttccatga caaatataac aattgatgag ataataacaa agtgaaattt gaaatcaaaa
    10801 aggagagcag atatccatga agggaatcat tcttgctggg ggcagcggaa cacgtctgta
    10861 ccctttaaca aaggcaacat cgaaacaatt gatgccgatt tatgacaaac caatgattta
    10921 ttatccaatg tctactctga tgttggcggg aatcaaagaa attctgatta tttcaacgcc
    10981 acaagataca ccacgtttca aggaattatt tggaaacgga aatgatttag gactgcagat
    11041 cgaatatgca gtacaagaaa gtccagatgg attggcacaa gcgtttatca ttggagaaga
    11101 atttattgga gatgatagtg tctgcttggt attaggggac aatatttact atggtggcgg
    11161 tctgtctaaa atgttgcaac gagcagcttc aaaagataca ggcgcgacag tatttggcta
    11221 tcatgtcaat gatccagaac gctttggtgt agtagaattt gatgagaata tgcaagcttt
    11281 gtcgattgaa gaaaagcctg ctcagccaaa atcaaattac gctgtaactg gcctttattt
    11341 ttatgacaat gaggtaattt ctatcgctaa aggtatcaaa ccttcagaac gtggagaact
    11401 agagattacg gatgtcaata aagcatattt ggataaagga aaactatccg tagaacttat
    11461 gggacgcgga tttgcttggc ttgatacagg aacacatgaa tcattgcttg aagcatctac
    11521 ctttatcgaa acaattgaaa aacgtcagaa cttaaaagtg gcttgtttgg aagaaattgc
    11581 ttaccgtatg ggctacatcg ataaggaaca attgctggcc cttgcacagc cattgaaaaa
    11641 aaatcaatac ggtcaatatt tattgaattt ggccgctgaa taaggagtcc ttacagatga
    11701 aagtaacaga tacaaaatta acagatgtca aaatcgtaga aatggacgtc tttggcgatc
    11761 atcgcggttt cttcacagaa agttattcaa aagcaaaatt tgcagaacat ggattgaaat
    11821 atgactttgt tcaagacaac cattcactat cagctgaagc tggtgtcctt cgggggcttc
    11881 atttccaaaa aggagaagct gcacagacaa aattgattcg ggtagtcact ggagcagttt
    11941 tagatgtagt agtggatatc cgcaaaggta gcccgactta tggtcaatgg gacggattta
    12001 tcttatctga acataatcat cgacagttgc ttgtacctaa aggatatgcc catggattcg
    12061 ttactttgac accaaatgtg aacttccttt ataagtgtga taattactat aatgcagaag
    12121 cagatggggg catcgcattt gatgatccag atttagcgat tgattggcca attgatccat
    12181 caagagcgat tatgtcggaa aaagatcacc gtcatccgac attaaaagaa tttgaagcag
    12241 aaaatccatt tgtttacgga gaaatctaag aattaaggag aaattttctt atgaaaaaca
    12301 tcattgttac cggaggtgcc ggattcatcg gctctaattt cgttcattac gtggtaaaca
    12361 atcatccaga agtgcatgtc actgttttgg ataaactgac ttatgcagga aacaaagaga
    12421 acttggccgg acttcctagc gatcgcgtag aattggtcgt aggagatgtt gcagatgcag
    12481 aattagtgga ccgtctagta aaagaagcgg acgcagttgt tcattacgcg gcagaatccc
    12541 ataacgataa ttcattaaaa gatcctttcc catttgtaca aacgaatatc attggtacgt
    12601 atacactttt agaagcttgc cgcaagtatg atgtacgcta tcatcacgta tctactgacg
    12661 aggtttacgg cgatcttcca ttacgtgaag acctgccagg acatggggaa ggcgaaggag
    12721 aaaaattcac tgcggaaaca ccatataatc cttcaagtcc atattcttct acaaaagctg
    12781 gttcagatct gttagtaaaa gcatgggtgc gttcttttgg cttacgtgca accatttcaa
    12841 actgttcaaa caactatggt ccttatcagc atattgaaaa atttattcct cgccaagtaa
    12901 cgagtatctt aagcggtatt cgtccaaaat tatatggcga aggaaagaat gttcgtgact
    12961 ggatccatac gaatgatcat tcttcagcag tgtggctgat tttgacgaaa ggcagaattg
    13021 gcgaaaccta tctgatcggt gcagacggtg aagaagataa taagaccgtg atggaattga
    13081 tcttagaaat gatgggccaa ccaaaagacg catacgacca tgtaaacgac cgcgcagggc
    13141 acgatttgcg ttatgcaatc gattcgacaa aattgcgaga agagctaggt tggcagcctg
    13201 agtttacgaa cttccgtgat gggttggctg acacgatcaa atggtacgaa gaacatgaag
    13261 actggtggaa aaaagaaaaa gaggccgttg aagcagcata tgccaaaaat ggacaataat
    13321 acagaggaaa tttcactgta ttaatggaaa aacacatgtg aggcaggcgc tcgcctgtct
    13381 cttttttaaa ataaaaatca aggagcggat aaccatatgt ttttattaac tggaggaaat
    13441 ggacaattag gtacagaatt gcgccattta ttagatgaaa aaaatctgcc atatgtttca
    13501 acagatgcaa aagacttgga tatcacagat gctgagaaaa caatggctta tattacagaa
    13561 ttaaaacccg atgttatttt ccattgcgca gcttacacag cagtagataa agcagaagaa
    13621 gaagcaaaag aattagatga gaaaatcaat gtcgatggca caagaaatgt agcacttgca
    13681 gcaaaagctg tgaatgcaca attcgtctat atcagtacag actatgtttt cgatggaaaa
    13741 aacaaaaatg tagaatacga agtagacgac caaacgaatc cactaaatga atatggtcgt
    13801 acgaaattat taggcgaaaa agcagtagaa gagattttag aagactatta tatcatacga
    13861 acttcttggg ttttcgggat ctatggacac aatttcgtct tcacgatgca acgcctagcg
    13921 gaaacccgcg acaaactgac tgtagtaaat gaccagtttg ggcgaccaac ttggacacgt
    13981 actttggcag aatttatggt atatgtcatc gaagaaaaag caccatttgg tatttatcat
    14041 ttgtcgaacg aaaatagctg ttcttggtat gagttcgcaa aagaaatatt gaaagataca
    14101 gatgtagaag ttgcacctgt tacgtcagaa gaatttccgc aaaaagcaac acgtccgcag
    14161 tattcagtca tgagcctgaa aaagacagaa gcgttaggtt ttgtcatacc aacttggcaa
    14221 gaagcacttg cgcaaatgct ggaagctgcc aaaaaaatga ataagtaatt tcctttttat
    14281 caaatagaat ttggagcatg atatggaaaa acaaacaaga agtgcacgac gaaaagaaaa
    14341 gccaaaagcg aatcaggcag attcgaattt ggtgcttgac ctgtttctaa aactccgcta
    14401 tcttattggc gttttagtca tcgtggtcat cgttactttt aatttaaacg gaagttcact
    14461 tggtgtttgg gataaatatg tgtcgcaaag agacgatggg aaaaaaactg atgtgatttt
    14521 tggacagaat cgggaagtgc ggtcagacga atggctggtg cagacacctt tttacctctc
    14581 acaagctgaa gaggactttt cgttggtgaa cgaggattat tcattaaacg gacaaaacat
    14641 gatcattgcg tataattctc ctgtaaagga tattacggtt atcggaaaac cattcaactg
    14701 gggattcttt ttcctcggaa gagatcgagg actttccttt tattgggcga tgaaattagt
    14761 cgtcatggtc ttgcttggat tcgaagtact gatgatatta acgaagagga aaaaagctct
    14821 atcgctaatc ggtgcatttg cgctgacatt ttctccagca gtccagtggt ggttcatgca
    14881 acatgtgggc gatttgattt tctttacttt gggactgatg attacttttt atcattattt
    14941 ctacaatcat gataaaaaat ggctacgaac gttgatgatg cttttggtgg ttattttcgg
    15001 tattgggttt attttagtga tttacccagc ccatcaagtg atgctggcgt acttgctgat
    15061 tttttatttt gttggcctgc ttatttacta tagcaagaaa gtttcatggg atctgttgga
    15121 tgtagtgttg attggagggg cagttttatt tattggcgga gtcatggttc atttctggct
    15181 aacgtcaaaa gacgcattgt tagcttcttt gaatacctta tatccaggaa aacgggtaag
    15241 tactggagga aagtggacga ttggcgaatt tttttctttc cttacaaatt ggaaaattcc
    15301 ttttgaagat atcaactatt cgaataactc tgaagtggcc ctgttctatc acttttttcc
    15361 aactgtattc ctagcaagtc catttgtgtt atttggcaaa aaagatagcg aacaaaagtt
    15421 actgggacgt attttgatga ttttttgtct gttttctatc ttttggatta ccgttgggtt
    15481 gccaaaatgg ctagcagaaa tcactctgct gtcttatgtt cctccattaa gagccatcct
    15541 tacttttagt tttgcggctt gtttattatc gatctggttt atcgcttata tttggagaga
    15601 agatgttatt cctatttggt ataaattcat tttgttggca gtaaatgcat ggtcttattt
    15661 ctatgcgatt acgcattcga aaatggataa ttatttttcg gattttgaaa ccatcgcagt
    15721 tgctgtgttg ggaacagtga ttttagcttt tgcattattt ggctggagac gcttgtttta
    15781 cctcgctttt gtcgccttag ttatcgtatc tggctttttc gtcaatccag tcgtagaagg
    15841 tacaggagcg atttttgaaa aaacactggc aaaagaaatc caaaaaatcg atcaacaaga
    15901 tcctggtaaa gtttggttgt ctgaagatga attatataac ttcaccccaa cattgggagt
    15961 gaaatccttc aatacagtac gcttttatcc agatatagct gcatggaaga aaatcgatcc
    16021 gaaagaagaa tacgagaagt attataatcg gtatgctcat acaagagctt ttatcgctaa
    16081 ggaagataca aagttcattt tagatcgtcc agatatgttt tcggtcacgt tgaattttga
    16141 agacgcagaa aaattaggga tcgactatgt gatcagtaaa cgaccattaa ctgattacaa
    16201 ccaattatat gaagcgcagt tcacgcagct atatggaccg gataaagacg gttatatgat
    16261 ttttaaagta gaatatccgg attatccaga tgtaccacaa acacaaactc aggaaaatca
    16321 gctagtcgta cagtaatagg ctagctgaga ataatcctga aatattagta gaaaggagag
    16381 tgaagataat tcaagcaatc gtacaaaaat ttgtcaacaa aatgagtgtc ggtttcttgc
    16441 ttttgttgct gacgctagtc ttttttgttt ggacagcagg ggtaggtttt ccagcaactt
    16501 tgtttatata taacaatagt tcattactta tcgcttttag tgtggctatt ttgctcattt
    16561 taaatgttta taaagcaaaa ggcgtcgatt ttctttatct aggtgttgcg cttgcccttt
    16621 tcattttctt ttcttacttt cgggaattaa gaaatgagtc tttatttgga gacttactgt
    16681 ttcctttgat tattttattt tgtttagtaa ttaaatggat cgagtggaca aaatgggatc
    16741 gcggtattta tctgattgtc tttacggtct tcctcggaat cacgttatat cgtgtattta
    16801 cagagatcca agtaccagaa ggacaaagca tctgggctcc aggcaattcg ctttctgata
    16861 tttggatcaa tacgaataca atcggaagtt ctttgatgac tcttgcttta ttgatcagtg
    16921 gatttgccag ttcttttgaa cgatggtatg ttcgaatcat cggtgggata gcagtcgttg
    16981 cagccttttt aggtatttgg gtctgccaat ctagaggtgc attagtcgcg ttgattgttt
    17041 ttgcgatatt ggatctttta cctaaatcgt tgatgcgtgt cattcgtgcg ccatttattg
    17101 cctacacggt tacgattctt ttagctttgc cgatttctta tctggcggct gtctctgaaa
    17161 aagtcaattt gtttaccggt cgagaagata tttggcataa attctatcag acgctaggag
    17221 aaaaatctga acaagtttta ctaggaatga aaacatttat cttccagcga ggaaaccaat
    17281 ttttaggaaa ccacaatagt tataattcta ttttgaatat ctatggattg ataggatttg
    17341 ggattgctgc tttgctgctt atccttttta ttggtcgctt aacgttgaaa gcagatttat
    17401 ccaacgggca gatgactttt atctgggcct tttttgcggt gatgatgcag tcatttatgg
    17461 aggatacatt gacttcatac cgatgggttc cgattattta tatcctgttg gctatggccg
    17521 ttcatcgata tgatgaacca gaagttacgg aggaattcta tgttatggaa gaggcatatg
    17581 acgatatgac ttatgatgat acatcttatg aggaacaacc agatagcgct cattcttcca
    17641 ggatccaacg ctatcattga taggcacaaa atacgagaga ggctgtgaca accgtcgcag
    17701 ccttttttgg tttattgcaa ttgtctagca tcttctgtaa aatagaaacg ttagagaaaa
    17761 tcttgtatca tagaaaatta agaaagaaat aagaacgcag ctcggtacca aaaatatggt
    17821 aaaatggcac ttgactgtaa ttcactgaaa atcgcttgga ggaacacaaa tgtttaaaga
    17881 tttgtattta tttatgaagg acatttatca gaacagaaaa ttactgctac agttttcgat
    17941 caatgacttc aaatcaagat atgcaggatc gtttttagga atcttatggg cgtttatcaa
    18001 tccgctattt actgtattga tttattggct ggtatttggt gttggactga aagcacaaat
    18061 gatcgatgca aaatacccat ttatcgtata tttagttacc gggatgattc cctggttctt
    18121 cttctcagat gcatttgcat caactacggt tgtttttcgg gaatatactt atttagtaaa
    18181 gaaagtcgta ttcaatattc gtatcttgcc cacgacgaaa atcctatcca atctgtacac
    18241 ccatttattc ttcattctga ttggcatagc tgtcgcgctt ataaatggta tatatccttc
    18301 agcaatgtct ttacagctga tttattattt attttgcatg tgtgctttct tgacaggatt
    18361 gacttggctg acggcatcga tccaaccatt tttacctgat atcatgcaat taattacgat
    18421 cgtgctgcag ttgatcatgt ggacattacc gatattatgg agccctaatc agtttgattc
    18481 aggtcttgta agcatattga aattaaatcc gctgtactat gttgttcaag gttatcgtga
    18541 gtcattttta agtgaagctt ggttctggga gcatggaaca tatactttgt atttctgggt
    18601 tttcacgtta gtaatgttcg taatcggctc tgcagtgttc cgtagattga aaccacattt
    18661 ttcagatgtg ctgtaaggag aatagctatg acagaatatg caattagact aaaagatatc
    18721 acaaaatctt ataatatgta cgcaaaacct tcggatcgat ttcgtgaagc cctcaatcct
    18781 tttaagaaat cctatcatga tgtattttat gcgttgaaaa acgtgaatgt agaaataaaa
    18841 aaaggtgaga tgatcggttt cgtgggagaa aacggatcgg gaaaatctac aatgttgaaa
    18901 atcattacgg gagtactgac accaacatcc ggcacgatgg aaatcgaagg aaaaatctca
    18961 gctttgctag aactaggatc aggattcaat cctgagtatt ctggctatga aaatatctat
    19021 ttaaatggaa tggttctagg attttcaaga gaagaagtcg atgaaatggt cgatgatatc
    19081 attgaatttg ctgacatcgg cgaccatatt tatcaacctg taaaaaccta ttcaagtggg
    19141 atgttcgttc gtctagcttt tgctgtagcg atcaatgtga atcctgatat tttgattgtg
    19201 gatgaagcat tggcagtagg agatcttgaa tttcaactaa aatgtatgga aaaatttaca
    19261 gaaatcaaga actcgggaaa gacgatttta ttcgtttctc atgatattag ttcgattcgc
    19321 cgtttttgtg atcgttccta ttggttgaaa aatggaaaag ttgtcgaata tggtgatacg
    19381 atggaagtaa cgacgaatta cgaaaacttt ttgaagaaaa aatcagttaa aacagtagat
    19441 cgaaataaaa accaagtaga acgcttcgca gctccagata tcgtagacgt gacgaaagcc
    19501 gaattgttgg ataaagataa aaatccagtg gatatgctgg aacaaggaga aaaactatac
    19561 gttaaagtaa cctatgaagt aaaagacgat acaatcaaaa atccagtttt aggaattgct
    19621 ctgcgtacag tcgacaattt ttatgtgtgc ggactcaata ctctactaga tggtatcaag
    19681 atcccttgga aaaaaggtga gaatatcttt tatctggagt atgaaaagtt aggtttgtta
    19741 gctggtgaat attattttga cgttgcggtc tttgaagaaa atgcaacggt tcctttggta
    19801 tacaagacaa aatacatgaa cttgtttgtc agcggttctt atatcggaga aggcatcgtg
    19861 gtcttagacc ataaatggga agaagggact catagcaatg aaatatgatt ttgaaatgga
    19921 cctagatgaa caaagcagtg tgggaaaaat tgccgcacag atcaaaccag gaagtaaagt
    19981 tttagagttt ggtcctggaa acggccgatt aacgaaacat ttgatcggag caaaacaatg
    20041 tgaagtgagc attgtcgagc tagataagga attgttcgat tttgtcagcg agtttgccca
    20101 agatggattt tatggagata tcgaaagttt tgaatgggca aactattatg ctggacaaac
    20161 atttgattac gttttgtttg ccgatgtttt agaacatttg gtagatcctg gaaaaacgtt
    20221 gaagaaagtt agagaatttt tgaatgaaga aggagaaatt ctaattacat tccctaacct
    20281 tgcgcataat tctgtcatga ttgatttgtt caataatcaa ttgccatggg cttcttatgg
    20341 tttgctagat gaaacccata attcttttta tactcatgat ggcttccaaa aagtttttga
    20401 aaaagcagga ttatacatca atattgaaga ttatttgtac ttagctgtag gtgatacaga
    20461 attaaaatca acttatgaag aattgccgga agctgtacgt tatgatttca aaatgcgacc
    20521 atttggcgaa gtctaccaat acttcttctc attgatgaaa catccagtag cacaaagttc
    20581 cattgcgcag ccgcaaaatt ctaattatgt gaaagtatta gaagtaatcc agcaaacgaa
    20641 acaagatgaa ataattcaac aaataccatt caataatttc acaggggaaa atgagacact
    20701 aagtttccat gtatcagaat tagcagaacg aatggtgttt cgcttcgcgc agcaacctag
    20761 ctttatcgaa ttcagcgcag aagctgctgg agaaaaactc acatttatcg attcaaatgc
    20821 tgtagtcaaa acagtaaatg attgttattt gtttgatggt aaagatttac cagagttctt
    20881 tttaacggat attgcaggga aagaagtgac tatccattgt cactatcgtt ttatcggaga
    20941 attgacacca acaatgaaag aattgctgga aacaatccgt ccaatggctg aagttacaaa
    21001 gcagctttct gagaaaaatg atgaattaga aagagaaaat cattatctta ttgagaataa
    21061 tacaagatta gatcagacgt tgaaaacaac cataaatcgc tattgcacgt tgttggaaag
    21121 tgatgaatgg acaatcaaac atagattagg gcgacgtaag aaagaaacat cgaaaaaaat
    21181 ccaagaaaaa gagctttctc tatgtattga cgaaaaaatc tgggatgcag aaacaaagat
    21241 attgaaaatc atcgggtggg gaatcgctaa ttcggatcgc caaccattgt cctataagtt
    21301 atcagccgac caatcaccat tttttgaagc aattcctgtt ttacgagaag aagtcaatca
    21361 agcaaaacag ctagctgaag gagcaaaagc aggatttgaa ctgcggatcc tttgcgagaa
    21421 ggaacgttca ttcttagttg aagcagtggc tcaaaatggt caatcatgga tcattgaaat
    21481 gtaaataatg attaacttat aaagataagg agtaaacgaa tcgtgcaaaa aaaagaaatt
    21541 gccgtattta tcgatcaaat cactcgtgaa cgggccactg gcgatttgct tattgtgggc
    21601 tgggcaattg atgaagtgac caaagaaatc cctacgataa aggtagaaaa agaaaatgtg
    21661 attgctgaag caacacatgt cgtaagattg gatatcaatc atttatataa tcttgatgtt
    21721 aagacccaaa gcggttttaa ggtacgttta tcagggaaaa tgagaggaaa agcaatctta
    21781 gacttccaaa cagcaagaca tcaaaatggc atagctgtga aattaaacgg taaatatcct
    21841 tatgatgacg gcattgaatc ttcatgggaa agaaaaaaaa gattactgaa aaaagggata
    21901 aattatgcaa ggactcatgg cgtaaaaaaa gcaatccgcc gggtcaaact ggaattgaaa
    21961 ccaggatcga tcgactatgc agagtggatc agtcgtcatg agaaacctga tctgaaagag
    22021 caaaggaaag aagtacaagg atttgcctac cgcccattga tttccatact tatgcctgtc
    22081 tataacgttg aaatcaaatg gctcgaaaaa tgcattgatt cggtacttga tcaaacgtat
    22141 gatcactggg aactatgtat cagtgatgat gcttctactg atccagctat ccgaaagtgt
    22201 ctagaatcct atcaagcaaa agatgataga attaaagtcg ttttccgaca agaaaatgga
    22261 cacatcagcc tggcaactaa ttctgcattg gaaatggcag aaggagagtt tatagcgctc
    22321 ttagataatg atgacgaatt acctccattt gccttatatg aagtggcaaa agtgctaaac
    22381 gtacatccag aactggattt gatctacagt gacgaagata aaatcgatgc agatgggaat
    22441 cgctttgacc cgcacttcaa agcagactgg tctcccgata cattgatggg aaataattat
    22501 atctctcact taggcgtata tcggacaagc attgttaagg aacttggcgg tttccgtaaa
    22561 ggatatgaag gctctcaaga ttatgatttg gttcttcgtg tgacagaaca aattcctgca
    22621 gaacacattt accacattga ccgtgtcttg tatcattggc ggacgatccc gggatcaact
    22681 gcaagcaatg gagaagctaa aagctacatc tatgattctg gagtgaaagc attgacagat
    22741 gctctatcta gaagaaatat caagggaagc gtacatcctg gcagaatttc tggtttttat
    22801 gaaatcactt atgatgtttt gcaagaagac ttggtcagtg tgatcattcc aactaagaat
    22861 ggctatgaag atctaaaaac ttgtgtggat tcgatcatcg aaaaaacgtc ttatccaaat
    22921 tatgaaatca ttattgcaga taatggaagt acagatccta aaatgcaaga attatttgca
    22981 gaatacaagc atcagctgaa agaccgattt atcgtcgaat taattgacat tccattcaat
    23041 tattcacgta tcaacaatct ggcagcagaa aaagcaaacg gcaaatactt tttattcttg
    23101 aataacgata cagaagtgat tgaacctgac tggatgacag cgatggtttc ttatgcacag
    23161 tttgatcgaa tcggctgtgt aggagcaaaa ctgttttatc cagatgatac aacgcagcat
    23221 gcaggagtat tattaggaat cggtggtgtt gcagggcatg cattgaataa ctatgatcga
    23281 acacattgtg gttatttcgg ccgattggtc attgacgtca attacttagc agtcactgca
    23341 gcttgtatga tggtcaaggc agctgacttc aatgctgtta acgggtttga tgaaacatta
    23401 gaagtagcat tcaacgatgt tgacttgtgc ttgaaagttt atgaactggg tcgttacaat
    23461 gtctatgcac atcaagcaga attgtaccat ttcgaatcta aatcaagagg ttatgaagat
    23521 actccagaaa aacaaagacg ttttgctggt gaaatcaaaa aaatgcaaga taaatggcca
    23581 gcatatattg cgcatgatcc attttacaat gataatttaa caaaagaagg aatcggcgac
    23641 ttttcgttga gaccagatta aactataata aaaagctgtt atgttgtgat tcgctcgcac
    23701 ataacggctt tttatagttt tttgtcaaaa aaaggcagaa ggtgccgact caaaaaaata
    23761 agtcgaggtt gggacagaag tgtttaactc cgagaaataa gaagaaattc acgaaaattg
    23821 cttttcaaat ttttgtgaat ttcggcttat ttaagaagaa gttgcttctg ctcccaccgt
    23881 ttattcgttt ttaaagaatg agacaaaagt gtttcttact tttgtcccac gctcttattc
    23941 atgctcagag cgccaataga tacaaaatca tagccaaagt ttcacgaacc ctagctgtca
    24001 aagaatcgat attttatttt aatataggct attttaaaat aaatggttta aggtattcct
    24061 ctacaaaagc cactctatca attatcatgg gtttaaaata agaagtgatg gagataacca
    24121 gattgttctt agcgtcaata taaagaacat ttccactatt accaattgct gaatatattt
    24181 cgttctcaga atctaatacc caccataaat agccatatct catattttgt aagtcttcta
    24241 aagcactggt tctaggtttg aacatctcgt ttatccacat gggtggtacg atttgttttc
    24301 ctttatacat ccctttattt aggcataata caccaatttt tgccagatca cttgccgata
    24361 aacacaaacc atatcctgcc gtcccgatat ttagtggatc acaaaaccag acattggttt
    24421 taggagactt atccattgta aactgcttat gttcttcagc tgtttcagca taataattga
    24481 catggtttgg tatccctata ggatcaaata gatacttatt ggcaaaatca acagttgtta
    24541 gcttacttgt ctgatacaac aagccagtta atatgtgtaa acagacagtt tgatagttga
    24601 attcgccggt tatacctttt cttcctccca ataaatctag tgatgttttt gtccaatctt
    24661 cacttgaaca gacttttgtc catggatcgc ctttacattt gtagggtgct ttcattgtta
    24721 gcaagtgctt gattgtaata gcgtaaatag ttttctcccc gcgtttcact ttatactctg
    24781 gaaaataatc taatacttta tcatcgatac ttttgattaa tccttgctct aaagcaatgc
    24841 caatcagcaa agatacaata cttttcgttg ctgacatgat atgacaagta tcgtcttttt
    24901 tataaccatt ccattcatct gtataaactt ctaccccatc cttatatgcg acaatttgac
    24961 atatatttgg ttgtcgaaaa ccaataaaat catgcaactc ttgtttattc ataagatatt
    25021 acctcacttt cttctataag cataatgtca ttaaaaatcg atttcaattt tttcgattct
    25081 tcacgtaata caggtattct tatggactag acagcgcttt gggaagatgg attctctgaa
    25141 aaatataaag gttcacttta tgagtggata aaaaaagcag caaatacttc gacttcttta
    25201 atttaccaac attagtgaaa atcgattcat ctggagattt gtaatttaga gtccttgtct
    25261 tgattagagg tgtataaagc tttttattag acatttttaa attccattac aatttgctta
    25321 taaactaggt ttttaaaggt gactatggta agataataga gatattattt tgtgattagg
    25381 agtgtatata tgaataaaaa tggagaatgg agtgctgcac gacggatatt cattatatta
    25441 atggatgtta ttgtatacaa tgcagcaata tatagtagtt tcttactgaa gtttcgtgga
    25501 gagatcccat tacgaaattt agaaactttc caacactcag caattattat ttcagtgatt
    25561 tttattgcgt tgaacatttt gttgggtgca tatgtttttt ataatcgaat gatcagtgac
    25621 atcgtgtttg tcacagtcat cggtcaggta ttgatgacac tagggatcat ggtagtgact
    25681 tttgcgggcc gctggtttgc ttttccacgt cttgttatct tactttcatt tgttctcggt
    25741 acgcttttct taagtatcta tcgtattctc gtatataaac tttatttacg cgtaagtcga
    25801 gataaaaagg tcgtcattat tgggttagaa aaggatgtcg caccagcaat ccaaaatttt
    25861 ggttcaaaga aaaacaacaa acataaagtc gaagcagtca ttcttgataa ctattatgca
    25921 aacatcaaaa atatgattaa agacatcgat attgtctatc ttgcttctca tatcgaagaa
    25981 actgaaaaaa tcaaaatcta tcaattagtt actaaaaatg aaaaaaaatt gtttttgaat
    26041 acaacatttg aaaacttgac attgatcaat ccaaatatta tgaatttcga agatgaaagt
    26101 attattgaag catctggatt tagaatccaa cctgaatatg aactattcaa acgtttgttt
    26161 gatatcatcg tttcacttgt tttattagtt attgcttcac catttatgtt attcacagca
    26221 attttagtca aagtgacatc accgggacca atcatctata aacaagtgcg gatcacaaaa
    26281 aatcaaaagg aattttcaat ctataaattc cgctcgatga ccgccacagc cgaagcaaaa
    26341 tctggaccag ttttagctaa gagcaatgat gcacgagtaa cgcctgtagg taaatttatt
    26401 cgagctgtcc gctttgatga attaccacaa atcttcaatg tgctgaaagg cgatatgtcg
    26461 atcgtaggac cacgtcctga acgtcctttc ttcgtcgatc agttcaatgc agaaaaccct
    26521 tattactact tacggcataa tgttcgtgct ggtatcactg ggtatgcaca agtctatgga
    26581 aaatatgtct ctgattacaa cagtaaatta cgttttgatt tactttatat caaaaaatat
    26641 tcattgatgc ttgatttaaa gatcttgctg caaaccatca agatcctatt tgataaaatg
    26701 tcctctcaag gacttgaaga agacgaaaat gtgatctcat tggcagaaat tgcttttccg
    26761 aatgaaaaaa tctttcgcta gttgggaggc gtaaaaatga acaatccgaa attcagcata
    26821 atcgtaccag tatacaatgc agaagcaact attggtcgaa agattgatat tctaaaagaa
    26881 ttggattatg aagagtacga agtcgtttta gtaaatgatg gatcaacaga tcaaacacag
    26941 gaaatcattc aagaactgat tgaaaatgat gaacgttttg aattgattac tacgaccaat
    27001 caagggcccg gattagcaag aaacgaagga ataagacagt caaaaggaga atatctctta
    27061 ttcttcgatg cagatgacac gccagtaaaa acgatcttgt cagattatga tcatttgcta
    27121 gaaaagagtc caaaagcgga tcttgttgtt agttcgtttg tttttcgtac aatggacgag
    27181 ggaagaatcg tttccgaaaa agaaaactta gttacagaat gtcactatct aactcacgaa
    27241 gagtttataa aagacatgta tcagttaatg aatgaacagt tgatgtatgt tgtatggaac
    27301 aaatgctatc gtagcgatat tctgaaaaat aaccaaattc tatttaaaac ttataatagt
    27361 tgtgaggatc gaatatttaa cttacattat tatgaatact gtcatcaagt gatcatgaac
    27421 ccaaaagtag aatatattta tgaatttgaa ggtgggaagg ggatcactaa tcaataccga
    27481 cctaacaagt tcgaaacatt taaagaattc tattcattag caaatactgt aacagacgat
    27541 attaataaag acggtatggc ggcgcttctt ttaaaaggga caacttcagt tattttttct
    27601 atttatagta cctctgcaag aacttcaaaa gagaagaaag acgaagcaaa gcagatattg
    27661 agtgatccag tgatccgaga agccaagcaa attgctaaga cggattcttc agcaaaaaaa
    27721 ataacaaagt tgctttacaa tatgccagct ccactatttt tatctgctgt aaaagttgga
    27781 agcttcgttg aagtgaaaat gccagggtta atggctgctt tgaagcgagt atattagtta
    27841 atggaggaaa atataatgaa aagaattttg cattttcagg gacgaatggg tttaggtgga
    27901 gcagagtctt tcatgatgaa tttatatcgt aaaattgatc gtacaaacta tcaatttgat
    27961 tttttgattt atgaagatta tgcagatgtt caagactatc attcagagat tgaaagatta
    28021 ggaggccgta tttttgttgt acctaatcct aagaaaaata tttttaaata tttaatagaa
    28081 gtgaataagt tactaaaaaa agaatctttt tctatagttc acaatcaggt ttattttggc
    28141 gggggaatta atttatggtt agccaaaaag aatggaatca gacagagaat tgctcatagc
    28201 catgcaactg aagatggaaa atctcaaaat attgtaatga atgtattgcg taaattttta
    28261 accaaattgt tgttacaaaa tgcaacagac taccttgccg ttagtcaaga agctggtgaa
    28321 agtctgtttc aaaaccatcc ctttgagata gttcataatg gtattgattt agagctttat
    28381 agtaaaaatt cagaagctaa ggttaataag agaaaagaat tggatatctc aatgagtact
    28441 tttgttgtgg gaaacattgg acgattagag aaacaaaaaa atcaatctta tttgttagag
    28501 atttttttag aaatactaaa aatgaattct gattcttact tgattttagt aggtgaaggg
    28561 tcacttagaa ataaactgaa agccaaagca gtagaattgg atatagagaa aagagtaaaa
    28621 tttttaggag aaagaaacga tattcccgag ttattatctg tgatggatgt ttttgtaatg
    28681 ccttctcttt atgaaggtct gccaatggtt ggattagaag cacaagcagc aaaattaaaa
    28741 ttagtcttag cagatactat ttccaaagat acaaagttaa caaataatgt ggattttgta
    28801 tcattagatg aaacaccaca agaatgggca aaaaaagtaa taaaagagcc gtatgctaat
    28861 aaaataacac aagaactaaa gagttatgat gtttcgtaca ctactgaaca aatggagagt
    28921 atatatagta gagatcatta aaaatgttca agatatttta ggagtgatta tttttgaaaa
    28981 tatgttattt gatattggca tacaatgata ttggcaactt aaagagattg gtcaatcgat
    29041 tgaacgaaaa tgcagttttt attattcata tagataaaaa aactgatata gaaccattta
    29101 ttgaagcatt taaatcatat gataatgttg aatttttatg taataaaaac cgtgttaaaa
    29161 tttattgggg tggtttttcc attgtacaag cagaaatcaa tttagtaaag agagcattac
    29221 aaaatgagaa atatttaaaa tatgtattat tatctggtgc tgattatcca atcaaagata
    29281 atgagtatat ttataattat tttaaaaaga atagttcagt ggagtttatt cgtggaatag
    29341 atctagatca aattaaacat aaagaatttt attataaaca tatagatgta tatcaaaaac
    29401 atgattatcc tagaattaat aggaataaca caactgcatt taaaattttt agagctataa
    29461 ttaatcgttg tctgaggatg attaaacttc ccccaaaaat tagacaccat aaatttgatt
    29521 tgtatcatgg ttctcaatgg tgggctttgt cgaaagaatg cctaacagaa ttaatacaaa
    29581 tgtatgaaca aaatcaacaa gactacctga attttaaaat aggtatgttt gccccagatg
    29641 aaaaattttt tcatacactt ttttttaatt cctcgttcaa aaataaaaat gttattggag
    29701 gaccagattt accacttgaa ttgaaaaata ttgaagaaac tactttacaa acttcgaaat
    29761 tagcaaatat tcatattatt gatccttcca tgaacaaatg gtttgatgaa agggatatag
    29821 atcaaataaa agaaagtgaa aaattatttg taagaaaagt taaatcggat tactctgata
    29881 aactattaaa tagaattgat aaagaaattt tgaaagttgg aaatatagat gaatagaata
    29941 gtacctgttt tagagaagag tttattaagt cgagatgcgt ttcgagtaat aaatttaatc
    30001 atttgtctgc tttattttat gcctagtact tttaatgtaa ctaatatccc gatgaaaata
    30061 gcttttgctt ggggtggaat tatagttttg tatgaggttt ttataaagaa aaattttttt
    30121 aaaatgcgtt tttcttggct actgattgga gcaatgatta gttttatctt aactataatc
    30181 attaacagag aaaatttttt aattccatct atttataatt ttggatattt gctgattact
    30241 ttgatagtaa tttttcctgc agacttttca caaagtgaag aggaaaaaaa gaaaaaaatg
    30301 gtgtatttta ataatgtttt cattatcata atttttttag ctgcgctaat atctatctat
    30361 caatttattt ttttgatttc ttatcatgtc ccaacaggaa cgccaggatt acttgcaaga
    30421 caaggtttta ttgaacatcg gttatttggt gtctatacaa gtccaaatgt tggagctatg
    30481 tttggatata cttctattat tttaagttta attagtgtat taatttcaaa aataacaaaa
    30541 acgattcgtg ttttttatat gatgaatttt atcgtacaaa tattttatat tacactttct
    30601 tcgtctagag gtgcccaggt agtaatttgt tcttttttag tattatttct tttgttgttt
    30661 gccaattcaa aatttagaaa gagcattaga gaagtactac ctgtaaaaat caaatggatg
    30721 gtaagcatat tattagttct attggtatat ttttcttttg gtactaatta tgctaaggat
    30781 tttttagcaa caattcctgt atcgattgat agaaaagtag aagttataga gtcaaatgaa
    30841 tcagataaaa ctccacttcc agaaaaagaa gtaatattac agcattctag tgataactcc
    30901 gaaatttcag ctggtcgttt tacgatttgg aaagctgcgc ttaaagttat aagaccaact
    30961 ttgttatttg gttatggaga gaccgatttc tatgggaata gcgatgcaaa atttttgaaa
    31021 aaagtagatc ttgatactac agatgtgaat gaactaaaaa gagcacatgg aaacatgcat
    31081 aatggatttc ttcaagtact tgtatcaagt ggtataattg cttttatatg tatctatgct
    31141 ttctatgtgt taaatatctt tagtttactc aaaacatttt ttagaagtaa agtgaattat
    31201 gcgtttcttg gtattgtttt aatttttata ctatctattt ttatagatga aatggtggag
    31261 gctcatgtac ttttcaataa gcgcgatgtc atttcaattg ttttctggta ttatttggga
    31321 agcatttctt acttgtattt aaaaaaggag aattaatatg aagacagctt tcattgcttg
    31381 gactccttta catttgatta atatattaaa tgtttatcaa aatttttacc gagaatcaaa
    31441 aggagattta tttatttatt ctgaatttga aaacgctaga agatatagtg agcgtataaa
    31501 agaattaggg ctatttaatg atgttgtttt tgtgaatcac cggaaaatcg gttcttcctt
    31561 taaacgtaaa attaacttgt taactaacca taatcaattt ttctcggatg atttatccgt
    31621 ttatgatgaa atttttatac agggggaaaa ttatttcaca aaaatacttt tctccaatgt
    31681 ttacaaaaaa aatccagatg taaaactaaa ttatatagaa gatggtttgg gtacttattt
    31741 gaagaagagt atattttcaa caagtaaaaa cgttcaaaga gtttttaaaa tattaaataa
    31801 aaatagcatc ttcaaaaaaa aaattgacga ttattttgtc tattgtccgg aattgttact
    31861 ttatgatgta aaaaatataa aaaaaattcc caaaatagat gaaaacagta aattgatgaa
    31921 aaacatacaa tcaatctttg ggatagaaga agtttttgtc ggagataaat gtatcttttt
    31981 tgatcaacct ttattatctg atggttatgg catagatgaa acagatattt tcgctaaagt
    32041 aaatagtata ttttctggaa aaaaagaaac tttaattaag cttcatccta gagcaaggac
    32101 aaatcgttat ggtgaaaaaa acatattgaa ttccagttta ccgtttgaag tcttgctact
    32161 tgaaaatgac ttctcttcaa cacttttgat tagtcctata tctacaattt ctttttcacc
    32221 atctatgatg tttgaaaaga cgatcaactc tattatgttg gctaaattaa ttttaaatga
    32281 atatacagca ttatctgaag ataaaaaaga aacattgaca aatattgttc ttttctgtga
    32341 acattataac cgtctatcag aagaaaaaat tttactccca gaaaactggg cagaattaag
    32401 aaagttggta gagtatggga ttatttaaca cactttccaa gtcaaaatta gttaagtcca
    32461 gtttctggta tactataggg aattttttta ttaagggaat ttcattcata actattccta
    32521 tttttgtaaa tattactact caagcagaat atggtttgat taataatttc acttcatttg
    32581 tatcaatttt ttcgattctt gttgggctaa gcctaaattc ggcaattaat aatgcaagtt
    32641 ttgactataa agatgacata aatgaattta tgtcatcggt actttctcta gctacacttt
    32701 cgttaattgt gttcttatta atagggaaca tatatttttt gttttcaaat gctttttttg
    32761 atatgaacca acttgtattt aatttgatgt tattacaaag ttttgctagt tttgtaatta
    32821 gttatatcca gtcttatttt acgattaact ttaaccattt taaatatttg attttatctt
    32881 ttatatctac ttttttgaat attgcaatct ctgtagcttt gatgcagaca ttatattttg
    32941 atgataaata tgttggcaga gtagtcggcg gaacactgtc atttgtgttg ataggtttag
    33001 taatttattt aagaataatg ataaagggtg ctcatttttt tgataaaaaa cagtggagat
    33061 acgctttaaa aatctctttg ccgctaatcc cacattcctt agcaaatata gttttagcac
    33121 aattcgatag aattatgatt aattcttatt taggtcctgc tgcgggggga atatattcct
    33181 acattagtaa cataggtatt attctaagcg taatatggat gtctactaat aacgcctggg
    33241 ttccatggtt ctatggtgag atgagtaaaa ataatgaaaa aaaagtgaag aaagttagta
    33301 actattattt agtagtcttt actttgatta cgatgattgt aatggtagtt tcgattgatt
    33361 tagcaaaatt tatggctccg aaagactatt attctgggtt atctttagtg gttccgataa
    33421 ccttaggcta tttctttcag tttttatata gtttaccagt taatgctgaa ttttatgaga
    33481 aaaaaacatc gtttattgcg attggtacag tagcaagtgc tatagttaat atactattaa
    33541 acatgatttt catacctagg ttaggaataa ttgctgctgg atacacaacc gtatttacgt
    33601 attttttact ttttattttt cattataata tcgctaaaaa aattacgaat aaacaattat
    33661 ttgacacaaa aaaaatatgt atcataataa tttttgtatc aattttttct ttgatacttc
    33721 atattttaat caatcaaatg ttgattcgtt acgttttgac atcattattg ataattagtt
    33781 tagttatata ttttttaaag attaagaatc gaattataga tgactataat tcataggagg
    33841 agatataagt gtttaaagga aaaacaatat tagtaactgg cggaactggt tccattggaa
    33901 gtgaaattgt tcgtcagctt ttaaaatatg aaccaaaagc tatcagaatt tatagtagag
    33961 gtgaagaaaa acaattttat atgcaacaag agctctcaaa tcacactaat ttgagatttt
    34021 taattggtga tatcagagac tctcaaagga ttgattatgc atgtcgtgat gtggatatta
    34081 tttttcatgc tgccgcaatg aaacacgttc cagcaagtga atataatcct atggaagctg
    34141 taaaaacaaa tgtgatggga actcaaaatg taatagatgc agcgatcaaa aataatgtaa
    34201 aacattttgt aggtatcagt acagataaag tagtgagtcc tactaacacc atgggtgcga
    34261 caaagttatt gagtgaaaaa ttaataatag ctgccaatca gtataaagga aaaacagaaa
    34321 caatattttc ttgtgtaagg tttggaaatg tcatggggtc aagtggatct gttattcctc
    34381 tttttagtaa acaaataaaa aacaataaag atattacttt gacagatgtt gatatgacac
    34441 gatttatgat gtcaataccg gatgctgcaa gattagttct gtctgctgct atgaattcaa
    34501 aatttggaga aacatatgtc ttaaaaatgc cggcaatcaa tattttaact ttagctcaat
    34561 cattaataaa aatatataat gatacacatg atgaaaaata tagaggtgaa ataaaagttg
    34621 taggtatcag gccaggagaa aaattatatg aagagctaat gactacagac gaaattgaac
    34681 gctcatatga aaatgataaa atgtatatca ttccaccaca ctatcatgct actgacgaac
    34741 tgtacaaaga ttatgaaaaa attaaaatca ctgcatactc ttcagatgca acagaattaa
    34801 tgagtggaca ggaatttatt agaatcgcaa aagagaataa tgtcgtgact tggtaaggag
    34861 ttttatgatg aaatcagaag tatatgtaat tgcagaaatt ggtgtaaacc ataatggaag
    34921 tctagattta gctttagaaa gtattgataa agctaaagaa tgtggagcta acgcggttaa
    34981 atttcaaaca tttaaaacga ataagctagt ttccaaaaag gctccaatgg caaaatatca
    35041 gaaggataat cttaaagagg acagttctca atttgaaatg ctaaaaaaat tagaattatc
    35101 tcaatctgat tttattagaa taaaagatta ttgtatacaa aataaaattg attttttgtc
    35161 tactcctttt gatgaagaaa gtgcagactt tctaaaacaa attggtgtac aaggatttaa
    35221 aattggctca ggagatttaa caaatttacc ttttcttaga aaaatagata tgtatgggtt
    35281 gccagtttta ttatctacag gtatggctga tattcatgag gtcagtgagg ctgtagattg
    35341 tttcatagat agtccagtta ctattttaca ttgtacttca aattatccgg ctagttctga
    35401 agatattaat ttattggcga ttaacacatt aaaagaaatg ttcgggatac ccgttgggta
    35461 ctccgatcat tcattgggat atgatgttgg tatttgtgct gttgcgatgg gtgctaaggt
    35521 aattgagaaa cattttacct tggataagga actacctggt ccagatcata aagcttcttt
    35581 agatcctcag gaatttgcag attttgtaaa gcatattaga aacactgaaa tatttttagg
    35641 tgatggtgtt aagcgagcaa tgccttctga acttagtaca aaagaagtat caagaaaaag
    35701 cctagtggtc actgagaatt taaatgtggg agatattctt acagagaaat ctcttacaat
    35761 aaaacgtcct ggaaatggaa tagctcctaa gtttttatat caatatattg gcaaaaaagt
    35821 taaaagacca ataagtgcag atagtgttct gcttgaggaa gatgttgaat gaaaaaaata
    35881 cttatagtaa gtggaacacg agctgattat ggaatatata aacctgttgc tgagaattta
    35941 ctacaagata attgggatgt atcatttgtt gtttctggaa tgcatttatc ccataaatat
    36001 ggatttacta aagaattgat cttagctgac ggatttagaa ttagtggaga agttcaaagt
    36061 ttgtttttag agaacaataa gggaaacatg gctcggtctg tggcattaga gataaatggt
    36121 ttcacaaata tatttgaaca aactagccct gattttgtat tattactagg ggatagagga
    36181 gaaatgttgg cagctgcgat agcttgtttg tatcttggaa tcaaaacagc acatattcac
    36241 ggaggcgaag tgtctggtac tgtagatgaa tcaataagac atgccataac gaaaatagca
    36301 tctgttcatt ttgctgctac ggaaaaaagc aaagagcgtt taataaaaat gggggaagat
    36361 tcttggagag tttttcccgt cggagctcct agaatagata ctattttaaa taatagatta
    36421 cctagtttta gagatataaa agaaaaatat catctaaaat ttgaaaagaa aaaatacgtt
    36481 ttgcaagtat ttcatccagt tgtaaccgaa ctagaaaata tagaaaaaca aattttagct
    36541 ttgatcaatt caatggaaca acaatctcaa ccaattattt gcattttacc taatagtgat
    36601 gctggtagcg aaattatcag aaaaatgtac cagaaatatt taaaaacgga tattatttat
    36661 attacgaatt tagagccgga ggaatacctg actatattaa aagagtgcaa atttatgatc
    36721 ggaaattctt cttctgggat aattgaagct gcatcattca aaataccagt aataaattta
    36781 ggaaccagac aaaatggacg agaacaatct aaaaatatta taaatgcaaa tctaaatgaa
    36841 aatgaaattg aaactgcttt gaataaaata caagatcctc agtttataaa aagcttgaaa
    36901 aatgttaaga acatctacgg tgacggcaac agttctagaa gaataacaaa aacattgaat
    36961 caaatattga atgatgggga agatattaag tggattcaaa aacaaatagc ttattaaaat
    37021 atactagtga tccatacatt attattgggg ctggcggaca cgcaaaagtc attattgaaa
    37081 ccttaagatt agaaaataag ttaatatatg gattttttga tgataagcaa aataaaatgc
    37141 aagatctgaa atatcttggg aaaataaacg aattgaatag ctgggcggat agcaaaaaaa
    37201 aaatctataa atttattgta gctattggtg actgtgtagt aagaaaaaag attataaaaa
    37261 aattgaatat gccaagtgag caatatggaa tagctgttca tccaagtgct atagtggcaa
    37321 aagaaatttc aattggttat ggaactgtta tttttgcgaa tgctgtaatt aacccagatg
    37381 ctgtaattgg agagcatgct ataataaaca caggtagcat tgttgagcat gattgtagaa
    37441 ttaataacta tgttcattta tctccaggtg tatgcttagc gggtggagta catgtaggtg
    37501 taggaactca aataggaatt ggttctcaat gtatccagat gaagaaaatt ggatcttggt
    37561 gtatgatagg cgcagggagc actattgtta aggatattcc ctcacattcc ttagcttatg
    37621 gcaatccagc taaaattaag aaagaaggaa ttaattttga attctagaat tttattatca
    37681 agtcctcata tgggaggaac agaagaaaaa tatgttgcta aggcttttaa agataattgg
    37741 atagcgccat taggtgaaaa tgtggataaa tttgaagaaa gtattacaaa atatactggt
    37801 tctaagggcg gagcttctgc gttaagttca ggtacagctg ccatacatct tgccttaaga
    37861 ctgcttaatg ttggaaaaaa cgatattgtc tttgctcctt catttacttt tatagctaca
    37921 gtaaatccta ttttatatca aggggctgta ccagtgttca ttgactcaga acctaataca
    37981 tggaatatga gccctgttgc actagagagc gcattagaag aagctgaaag aaacaaccaa
    38041 ttacctaagg caatcatcgt agtgaattta tatggtcaaa tggctgatta tgaacgaatt
    38101 ttagctattg caaaccaatt taatgttcca gtgatagaag atgcagcgga atcgttaggt
    38161 tctacttata agggaatttc gtcaggctta tttgggacaa ttgggatcta ttcatttaac
    38221 ggtaataaga tcatcacaac ctcaggtgga ggagctctag tgtctagtga taaaaaatat
    38281 gttgagcatt caagattttt agcaacacaa gcaagagatc aagcaccgta ttatcaacat
    38341 agcgaaatag gttataatta ccgtctaagc aatatttctg ccggtatcgg acgtggacaa
    38401 atggaagtat tgaatgatag agtagctaaa cgaagagaaa ttttcaatcg atataaggaa
    38461 gctttttctg gaattgatag aattgaaatg atgccagaag tggatggcat ggtgccaaat
    38521 cgttggttgt ctactttaac gatcaatgat tataattcta ttgatcaagt agttaacgta
    38581 ataaataaac taaatgaaaa aaacattgaa acaagagctt tgtggaaacc actacatttg
    38641 caaccagtat ttcaaggggt aaaaatgtat taccatgata ataatcttag tgtgtcagaa
    38701 aagttattta atagcggctt atgcttacct tctggaagta atatgacaga tagtgaacaa
    38761 gaatttgtta ttgatgagtt taaaaaaata ttcaagtagg tgtgatattt tatgaacata
    38821 ggaattattg gtttaggttc catggggaaa agaagactta gactcattca agaacacttt
    38881 aatgatattt tactatgtgg tgttgatact aatgaggcga gacgaaagga agttgaaaag
    38941 gaatttggaa taccaactta taatagtcta acagaggcaa aaaatttgtt tgaaataaat
    39001 tcagtttttg tttgtacatc ccctataacc catgaattta ttataaaaga ggctttaaat
    39061 ttagattgta atatctttac ggaaatcaat ttattaaatg aatattatga tgaaataatc
    39121 gaagtagcta aaaagaaaga tagattactt tatctatctt ctacattttt gaagagaaaa
    39181 gaaattcaat atattaagtc taaagtgacg cataataaaa aaatttctta tcaataccat
    39241 gtaggacagt atttacccga ctggcatcct tgggaagatt atcgcaattt ttttgtttca
    39301 aacaaaaaaa ctaatgggtg tagagaaata ttcgctattg aattaccttg gattatagat
    39361 acatttggga aagttaaatc gtttactgta atgacccaga aattatccaa tcttgatatt
    39421 gattattcgg acagtttcac tcttattatt gagcatgaaa ctggtatagt tggaacttta
    39481 agtgtagatg ttgtttcaag agtagctaaa agaaatttaa ctataattgg tgaaaagatt
    39541 ttaatagaat gggaaggtaa cccggattct ctattttcat ggaatgaaga aacttctagt
    39601 atgacagata ttcaattgta cgatgaggtt atgcatgata ataattattc acatactatt
    39661 attgaagatg catatttaga ggagattaaa gaatttttca cgcttttgga aaagaaaatg
    39721 gaaccccaat atacttttga aaaagataag tatattatta acttaattaa cgacattgag
    39781 gtaaattaat gatgaaagta attttttttg ggttagggtc aattggaaag agacatctaa
    39841 aaaatctaat aagctatgga aaaaagaatt ctattaattt tgatataaca gcttatagta
    39901 gcagtggaaa aaaagagttt gaagaaataa cgtatattca aaatagagac gatttggata
    39961 cacattatga tatagctttt attacaaatc cgacttttaa gcatctggaa acactaaatg
    40021 taattgttga aaaagttgat tacatatttt tagaaaaacc tgctttttct gagagtattg
    40081 atcttactca atataattat gattacaaaa atatttatgt tgctgctcca ctgaggtata
    40141 aaaatatcat ggaagttgtt cgtaatagta ttcaaagtaa aaaagtatat tctgtaagag
    40201 ctatttgttc tacttatctt cctgattgga gaaaaggtac tgattataga aataattatt
    40261 ctgcctttaa atctatgggg ggaggagtag aattagactg tatacatgaa ttggattata
    40321 ttataaacct atttggtttc cctaaatcag taaaaaaaca gtttggtaaa tattcgaatc
    40381 ttgaaattaa cagtaatgat ttagcaacat atatattgag atacgatgat aaaattatag
    40441 aaattcattt agattatttt ggaagagttc ctacaagaaa atttcaattg tttactttag
    40501 atgaatgtat caatgttgac ttattaaata ataaaataag ttttgaagaa aacattgtta
    40561 aagaaatgcc tgaatctgct aatgatatgt atgagaagga gttgaaatat ttctttgaaa
    40621 acgtagtaac aggcaaagaa aactggaatg atttatatca tgcaaacgaa gtattgaaaa
    40681 tagctgagga gaaataaatg gaaattttat ttactatttg tggtagagct gggtctaagg
    40741 ggtttaaaaa taaaaatttg aaatatttgg caggaaagcc cctagtccat ttcgctttag
    40801 caatgataga tatctatcaa caaaaacatc ctgaacataa ttgcacgact tgtttgaata
    40861 cggacagtaa tgagttagta gaattgacga ctaagttaaa tccgtctgtg aaaattgtag
    40921 aacgtaaacc tgaattagct acagatactg tagggaaaat tgaagtgata cgtgattcat
    40981 tcttacaact agaaagagaa gataatatat ttgatttaat tatagattta gatttgactt
    41041 cacctttacg tgaagtttct aatcttgaag aattaataga tgaacatcta aaaaatttag
    41101 ataaagacgt ctacttttca gttgtttctg caagacgtaa tccctatttt aatatggtaa
    41161 aaagaattga aaatgaagtt actatagtta ataaatcaag atacacatct aggcaacaga
    41221 cacctgaagt ttttgaaatg aatgcctcaa tgtattcttt taaacctgaa tttctaaaaa
    41281 aaagtaatta tatttttgat gggcaatgtg ggataataaa aatgagagat tatctaattt
    41341 tagatattga tagtgaagaa gattttaaat ggttagaatt tttgtttcct aaatttttag
    41401 aagattcttc ggagcttcaa gatatctata attatttata tcggaggtaa aaggatgagc
    41461 tgttatctta tcaccggtgg ggctggcttc attggttcta ccttagccaa tcatttagga
    41521 gaagaacatg tggtaatcgt cgtcgatgac ttatcaatgg gaaaagtaga aaatcttgat
    41581 atgacgaaaa atatcacttt tattgaggga gatgtcgctg agaaatcctt gatggaagag
    41641 atcatgaaag ctaataaatt tgattatatc tttcatttag cagcagttgc tagtgtggca
    41701 gattcagttg cccgaccagt agaaacacat cgtgtgaatt ttgaaagtgt attaatgatt
    41761 ttagaattga tccgcaagta tcaacctgat ttaaaacgga tcgtgtttag ttcttcagcg
    41821 gctgtttatg gggatgaacc gactttacca aaaaaagaag agtccgtgat tcgcccattg
    41881 acgccttatg cggttgataa attcgctgca gaacaatatg tgctagatta ttgtcattta
    41941 tatgatgtac ccggtagcgc agttcgtttt ttcaatgtct atggtccaaa tcaaaatccg
    42001 aattctccat acagtggtgt gatttctatt ctcgtagatc gctataagaa acaaatcgta
    42061 ggagaagcaa cttcatttac attatttggt gatggaagcc agtctagaga ctttgtttat
    42121 atagatgatg taatccaagc attactttta gttgcgaatg aggaagctgc actggggaaa
    42181 caattcaatg ttggaacggg taaagcaacc acacttttgg aattgattca tgcaatcaat
    42241 gaaattctcg gtgtagaatt gacacttgaa tacaaagaag agcgttcggg tgatatccat
    42301 gactctctag cagatattac taagatccag tcaattggct atcaaccgaa atatggtatt
    42361 ttaagtggaa tgactaatta tttgaaaact gaaatcaatt aaaacatact aagataagat
    42421 tagagggtaa attcaggctc tttgtcaata aggactgatg agttttgtaa aatcaaatct
    42481 gggatagaa
//
LOCUS       DAYNVV010000017        40656 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.017, whole genome shotgun sequence.
ACCESSION   DAYNVV010000017 DAYNVV010000000
VERSION     DAYNVV010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.017"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(61..2424)
                     /locus_tag="ACGXWR_001086"
     CDS             complement(61..2424)
                     /locus_tag="ACGXWR_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase"
                     /protein_id="HFK0802684.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            2589..3093
                     /locus_tag="ACGXWR_001087"
                     /pseudo
     CDS             2589..3093
                     /locus_tag="ACGXWR_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035543.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="ACGXWR_001088"
     CDS             complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="ACGXWR_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HFK0802685.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(3575..5881)
                     /gene="infB"
                     /locus_tag="ACGXWR_001089"
     CDS             complement(3575..5881)
                     /gene="infB"
                     /locus_tag="ACGXWR_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HFK0802686.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(5894..6205)
                     /locus_tag="ACGXWR_001090"
     CDS             complement(5894..6205)
                     /locus_tag="ACGXWR_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HFK0802687.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(6202..6495)
                     /locus_tag="ACGXWR_001091"
     CDS             complement(6202..6495)
                     /locus_tag="ACGXWR_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HFK0802688.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="ACGXWR_001092"
     CDS             complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="ACGXWR_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HFK0802689.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="ACGXWR_001093"
     CDS             complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="ACGXWR_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HFK0802690.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(8333..12685)
                     /locus_tag="ACGXWR_001094"
     CDS             complement(8333..12685)
                     /locus_tag="ACGXWR_001094"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFK0802691.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            complement(12897..14606)
                     /locus_tag="ACGXWR_001095"
     CDS             complement(12897..14606)
                     /locus_tag="ACGXWR_001095"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFK0802692.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="ACGXWR_001096"
     CDS             complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="ACGXWR_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HFK0802693.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(16103..16903)
                     /locus_tag="ACGXWR_001097"
     CDS             complement(16103..16903)
                     /locus_tag="ACGXWR_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFK0802694.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(16900..17712)
                     /locus_tag="ACGXWR_001098"
     CDS             complement(16900..17712)
                     /locus_tag="ACGXWR_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HFK0802695.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(17907..18464)
                     /gene="frr"
                     /locus_tag="ACGXWR_001099"
     CDS             complement(17907..18464)
                     /gene="frr"
                     /locus_tag="ACGXWR_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HFK0802696.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(18467..19189)
                     /gene="pyrH"
                     /locus_tag="ACGXWR_001100"
     CDS             complement(18467..19189)
                     /gene="pyrH"
                     /locus_tag="ACGXWR_001100"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HFK0802697.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(19325..20206)
                     /gene="tsf"
                     /locus_tag="ACGXWR_001101"
     CDS             complement(19325..20206)
                     /gene="tsf"
                     /locus_tag="ACGXWR_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HFK0802698.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="ACGXWR_001102"
     CDS             complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="ACGXWR_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HFK0802699.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            21446..21925
                     /locus_tag="ACGXWR_001103"
     CDS             21446..21925
                     /locus_tag="ACGXWR_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFK0802700.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            22142..23233
                     /gene="phnW"
                     /locus_tag="ACGXWR_001104"
     CDS             22142..23233
                     /gene="phnW"
                     /locus_tag="ACGXWR_001104"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HFK0802701.1"
                     /translation="MYKLLTPGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSGSFGVESVLSSVIRPEDTVLICSNGAYGQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQEKDLL
                     FIVDAMSSFGGIPIRVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            23226..24011
                     /gene="phnX"
                     /locus_tag="ACGXWR_001105"
     CDS             23226..24011
                     /gene="phnX"
                     /locus_tag="ACGXWR_001105"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050194 - phosphonoacetaldehyde hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HFK0802702.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(24357..26048)
                     /gene="argS"
                     /locus_tag="ACGXWR_001106"
     CDS             complement(24357..26048)
                     /gene="argS"
                     /locus_tag="ACGXWR_001106"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HFK0802703.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="ACGXWR_001107"
     CDS             complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="ACGXWR_001107"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HFK0802704.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(27532..28551)
                     /gene="argF"
                     /locus_tag="ACGXWR_001108"
     CDS             complement(27532..28551)
                     /gene="argF"
                     /locus_tag="ACGXWR_001108"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HFK0802705.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="ACGXWR_001109"
     CDS             complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="ACGXWR_001109"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HFK0802706.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            30332..31033
                     /locus_tag="ACGXWR_001110"
     CDS             30332..31033
                     /locus_tag="ACGXWR_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFK0802707.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="ACGXWR_001111"
     CDS             complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="ACGXWR_001111"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HFK0802708.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIVAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="ACGXWR_001112"
     CDS             complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="ACGXWR_001112"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFK0802709.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLVEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="ACGXWR_001113"
     CDS             complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="ACGXWR_001113"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFK0802710.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTIEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(33615..34337)
                     /gene="tsaB"
                     /locus_tag="ACGXWR_001114"
     CDS             complement(33615..34337)
                     /gene="tsaB"
                     /locus_tag="ACGXWR_001114"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HFK0802711.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDKIIVPMFDARRKNVYAGAYRWKENRLEIVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFYEIKEILPSAMINTVPAWDIPSGVTVAQLGALAEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(34528..35508)
                     /locus_tag="ACGXWR_001115"
     CDS             complement(34528..35508)
                     /locus_tag="ACGXWR_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFK0802712.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPTDGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(35532..37016)
                     /gene="galT"
                     /locus_tag="ACGXWR_001116"
     CDS             complement(35532..37016)
                     /gene="galT"
                     /locus_tag="ACGXWR_001116"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HFK0802713.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLADYPQVIAGVVKWPMSVIRLQSTEKKLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(37028..38017)
                     /gene="galE"
                     /locus_tag="ACGXWR_001117"
     CDS             complement(37028..38017)
                     /gene="galE"
                     /locus_tag="ACGXWR_001117"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFK0802714.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREVLGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            38266..38433
                     /locus_tag="ACGXWR_001118"
     CDS             38266..38433
                     /locus_tag="ACGXWR_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HFK0802715.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(38495..40306)
                     /locus_tag="ACGXWR_001119"
     CDS             complement(38495..40306)
                     /locus_tag="ACGXWR_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HFK0802716.1"
                     /translation="MKIGIIGAGPRGLSIAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNDLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSREGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGSMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLEIPLTYQDESFAEASRAFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPVIRTKELAALIDAGIFHLFEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(40303..>40656)
                     /locus_tag="ACGXWR_001120"
     CDS             complement(40303..>40656)
                     /locus_tag="ACGXWR_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HFK0802717.1"
                     /translation="KRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIAPSNE
                     ARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKNEHQN
                     HAVLLKKFIEMEACK"
BASE COUNT        11050 a         8686 c         7200 g        13720 t
ORIGIN      
        1 cttaatttga caaataatac aatgtaaaaa attctgtttt gcgggatcga ttttatcatt
       61 ttattggtca agatttttcc atttccaatc caatacttct ggcagatcaa taccattttc
      121 acgaatatag ttttgatgtt cttgtaattt ctgatccatt ttttccgcaa aatcttctgc
      181 ttgacttcct ttgattttta aagctgcgtc ttttgccaaa tgataacgat caagttcatt
      241 tactacacgc atgtcaaatg gtgtcgtgat atctccattt tctttgtagc catgaatcat
      301 taaatgatgg ttatgacgat caaagaaaat cgtgcggacc aatgtttcat aaccgtggaa
      361 agcaaataag atcggtttgt cttttgtaaa atattgatca aattcttcat cgctcaaccc
      421 acgcggatct tgacttggat gacgtaattt caataaatct acgacattga tgaaccgaat
      481 ttttagtttt gggaattctt ccagcagcaa agttacagct gctaatgctt ctaagttaga
      541 ttccgttcct gcagcagcaa tgaccaattc aggttcctcc tcttttgctg tcgaagccca
      601 atcaatgatt ttcaagcctt cattcactaa gacggctgct tcttctgctg agtaaaattg
      661 agcacgcgga tgtttggaag agatgatcaa attgattttt tctgacgagc ggaatgcttt
      721 atccatgact gcgagcaatg tatttgcatc cgcaggcaga tattcacgga tgaactccgc
      781 cttcttttct gccaaatgtg tcaatattcc tggatcttgg tggctatatc cattgtgatc
      841 ttgctggaag actgttgagc ttgcaatgag attcagcgaa ggataatctt ttcgccaaga
      901 aaggtcatgt gatttccgta tccatttgaa gtgctgagtc aacatagagt caaccactcg
      961 caagaatgat tcgtaacttg caaaaaaacc atgccgtcca gtcagaacgt acccttctaa
     1021 gaacccttca tcttggtgtt ccgataattg actgtcgatg acgcgaccag atggcgaaag
     1081 ccattcatca ttttctggtt cgattttttc catccattgg cgatttgtcg ttttgaaaac
     1141 ttgattcaat cggtttgatt ttgtttcatc tggtccaaat atacggaaat tttctggatt
     1201 tttctcaatg atctcgcgaa cgaatttacc aagttcggtc atatcttctg ctttaacgga
     1261 gcctggtttt tcaaattgca aagtatattt tttccaatct ggcataataa gcggtcttgg
     1321 atcgattcca ccattggtga taggattttt tgccattctt tggtcaccag taggcgcaat
     1381 ttctctgatt tcttctaaaa tacgtccttg tgcatcaaat aatttttctg gttcatagga
     1441 tttcagccaa cggagtaaag catctgcatg atccatatgt tcttgatcta caggaatcgg
     1501 tacttggtgt gctcggaagg ttccttcaat tggttccccg tcccattctt ttggaccggt
     1561 ccatcctttt ggtgtgcgta cgatcaatac tggccatttt ggcatcacga catctgttgc
     1621 tgtcttcagg cgagcttctt tttggatgga tttgattttc tcgattgctt gatccatttt
     1681 ttcagccata acaggattta atttttctgg atcatttcct tcaataaaga aaggctccca
     1741 gccaagtccg ttaaagtaat ttgctaattc tccatctgat ttacgtgcca agatcgttgg
     1801 gttggctatt tttgcaccat ttaaatgaag gatcggtaaa acagctccat ctatcactgg
     1861 attgataaag acatttgaga accagcttcc agctaaagga ccggtttctg cttcaccatc
     1921 accaatcacg acagcagaga ttacttcagg attgtctaat acagctccga ctgcatgtga
     1981 aagagagtat ccaagctctc cgccttcatg gatagaacct ggtgtttctg gtgctgcatg
     2041 agaagcaatg cctccaggaa atgaaaatcg cttgaataat ttttgcattc ctgtctcatc
     2101 ttccgttact tctggataga tctctgtgta acttccatct aaataagcat tcgataccat
     2161 gacttgtccg ccgtgtcctg gcccttcgat ataaaacatg ttcaaatcat atttattgat
     2221 gactcggttc aaatggacat aaataaaatt ttggccagga atcgttcccc aatgaccgat
     2281 tggatgtttt ttgacatctt ctggtttcag tgtacgtctc agtaaggggt tatctttaag
     2341 ataaagttgc ccaacagaaa gataattagc agcacgccac caagccgtca ttttatcaaa
     2401 gtattcttta ctagaataat ccatacataa cactcctttt cattattact cttattctag
     2461 cgcagatact cccaattgaa acctaataag cacttctgtt catttgtttg gattttatat
     2521 ctagccaaat gaacaggtat aaaaaaccac gaaatttttc ctttcgctga cgttttttac
     2581 attgatccaa aaaacttgtc gttatcacaa tggctgttcc gcagttcatt tcgctcctca
     2641 tcatgcataa tttgctgaat gacgctaggc cagttaacac attgttggaa aactggggct
     2701 ggatcgagca attcctttcc tgattgatcc gttttatgta aaagtctctg ttatctttgt
     2761 caatatgtga attggtatcc cagctactat gctaatttct acagggatta tccaaaattt
     2821 ggatcgtgac caaatcgaag cggcgtaatc ggaaatatca ataacttcaa cgtgattttt
     2881 cttttaactg tcaacggacc gacaaactca aacttttatg gtgcaggttc cactgatctt
     2941 ctagttactt ggctatacct gactgtcact aaaatagatt acaatctagc ttccgttatc
     3001 ggtatcttga tctttatcta tatgcaaaaa tttatatact atagaaaaaa gaaagtcgaa
     3061 ttttttactt ttctttttct cttttttggt tagctgacac gctaccagac taaagtcatg
     3121 gaactcttag gtaatacgtc ttaatgaaaa caaaaaaatc ccgcaacccc tgatttcaca
     3181 ggatttgcgg gattttttga ttagtctttg ttcaagtcgc gaagcaattc atcgatatgg
     3241 ttcccataga caactgattc atcaagttca aagaacaatt caggtgtctt ataaatactt
     3301 agattgtgcc ctaactctcg acgaatcaat cctgatgctt tattcaatcc atcttgtgct
     3361 tttttcttat ctgatgctaa gtcagataaa atgctgtaat agatcgttgc ttgctgtaag
     3421 tcccccgtaa ctttcacatc tgtgatcgtt acgttctcca cacgagggtc acggaccttt
     3481 ttgcgcaaaa tatcattgac ttcttttaag atttcttgac cgactcggcg atcacggtag
     3541 ttagccataa tgattggcct ccttttatca gtttttagtc atttttgact tcttccatga
     3601 taaatccttc aattacgtca tctactttga tgtcattgaa tttttcaatc atcgcaccac
     3661 attcataacc cattttgact tctttcacgt catctttgaa tcgtttcaga cttgcaagtt
     3721 ggccttcata gattacgatt ccgtcacgga ttacacggac accgctatct ctacgaatat
     3781 atccttctgt tacataggca cctgcaatcg taccaacttt agaaactttg aaggtttcac
     3841 gaacgatcat ttgaccggtg attttttctt caaattcagg gtctagcatc cctttcatcg
     3901 cagtttcgat ttcttcgatg gctttataga tgatacggtg aagacgaata tcgacttctt
     3961 cagtatcagc ttgcactttt gcctgcggtg taggacgaac gttgaaaccg atgataatag
     4021 cgttgctggc tgctgctaag gttacatcac tttcattgat tgctccgaca gctgaatgga
     4081 cgatttttac acggacacct tccacatcaa tcttcttcaa tgatgcagcc agtgcttctg
     4141 ctgaaccttg tacatctgct ttgatgatta cgttaacttc tttcaattcg ccttctttca
     4201 ggctttcaaa taagttgtcc aaagtcacac ggcttgtggc agcacggttt tccaataatg
     4261 cacgttttgc gcgttcttca cccgctgcac gtgctgtctt ttcgtcttcg aagactacga
     4321 aacggtcacc tgcttgaggt acatcattca agccagtgat ttctactggc gttgcaggtc
     4381 ctgcttcttt atcgcgacgg ccaagatcgt ttgtcattac acggacacgt ccgtaagtat
     4441 taccgacaac gattgggtca ccaacgtgaa gtgttccttc ttggacaagt aaggttgaca
     4501 caggaccttt acctttatca agacgtgctt cgatcactgt tccgattgcg cgttgtgttg
     4561 gatctgcttt taaatcttct acttctgcga ctaacaggat catttccagc aattcttcga
     4621 tgttttggcc gaatttcgct gagatctcaa caaaaatcgt ttctccaccc catgcttcag
     4681 gaattaattc atactcactt aattcttgca taacatgctg aggatttgca cctggtttat
     4741 caattttatt tacagcgacg atgattggaa cgcctgcagc tttggcatgg ttgattgctt
     4801 caactgtttg tggcatgacg ccatcatctg cagcaacaac taagatcgtg atatctgtga
     4861 tacttgctcc acgtgcacgc atacttgtaa aggccgcatg tcctggtgta tccaagaaag
     4921 tgattggttt accatcaata tcgatctggt aggcaccgat atgctgtgtg attccgccgg
     4981 cttcgccgct tgttacacgt gaatggcgca atgtatccaa taaggttgtt ttcccgtggt
     5041 ctacgtgtcc cataatcgtt actactggcg gacgtgagac taatttatct ggatcgactt
     5101 cttctgcctc gaagaattta tcgatatcag caatgtcaac ttggactttt tcttgtggtt
     5161 ccatgccata gtccgtcgct aacagttcaa tcgtatcttt atccagtgct tggttttgat
     5221 tgaccatgac accaagcata aataattttt taatgatttc tgctggctca cgatgaattt
     5281 ttttcgcaat atctgctacg ttcatacctt cagtatactc taatacatct ggcaattcac
     5341 ggaatttgcg tggtggtaca gctggtttag ttgattgttg ctgtttgcct tttttacctt
     5401 ttttattata acgattacgg ttattattat taaatttgcc gcgattgtta ttgtttggtt
     5461 tgttgttatt gttagtacgg ttttgattgc cgccttggct cgttccttga cgattttggc
     5521 tgctggtatt tcccgtatta ttttggtttg ttgttggttt ttttccttga ttcacttgac
     5581 cgctcccttg accgcgatct tgataactgc ggttattttt atttttttgt tgattgttcg
     5641 ttgtttcttt tttacgttga tcgttcggct gttgattggc tggttttctg cttgcttgtt
     5701 gtgcagcttg ttgtttcgtg cttgggtttt tgaacgcttg ttgcaatttc ttctcatcac
     5761 tgctagtaat cgcacccata tggtttttca catcgatgcc aagttgttgt gctttttcca
     5821 cgacgtcttt actagatttt ttgagttctt ttgctaattc atagattctt ttgttgccca
     5881 tgcaatcacc ttcctaacct tcaattagct ccttggtctt cttcgcaaat ccggcatcca
     5941 ttattccgaa taccttgcga ggttttccga tcatctgcgt gatttctgct tcagaaaata
     6001 gctcaaagca aggaacttca taatatgaac tcttatcttt tatctttttt cttgtattct
     6061 cacttgcatc ggttgccaca aacaccaatt ttgctttttg tttgcggatt tcagcaatgg
     6121 tcagttcttc acccgtgatt agttttcccg cgcgcatcgc tagaccgatg agattcatgg
     6181 ctttttgccg attaactgta ttcattttcc aaataactct ttacgtgctt tttggtgagt
     6241 gacatagtca agaagttctt gataaaactc atctgttaat gttgtttcga gtactcgatc
     6301 gagaattttt ttatcccaag cttgttgtac ttcttccggc tcaagtgaga catacgctcc
     6361 tcgtccaggc atttttccag ttggatcgat cgatacttcc ccttcttttg aacgggtgat
     6421 tcggaccatc tcttttttag gtttcatttc acctgaaacc acggatttgc gtaaaggaat
     6481 tttcctttgt ttcatctctt tgcctcctta ctaaagttaa gcttctggtt tttcttcgac
     6541 cgtttcattg ttgaatgcaa ttgtttcata ttcatcgtct gttaaatctg actgaacgat
     6601 tgcttcatca tgcagttctt ctgtttcttt ttgttgttct tgattttcat aaaattccgt
     6661 catgtcagat tctgatttga tatcgatttt atggttagtc aatttagcag ctaaacgtgc
     6721 attttgtccg cgtttaccga ttgctagcga taattggtag tctggaacga caactgtgca
     6781 ggcctttgga tttgtctcat cgaagatcac atccatgact tgtgcaggat tcaatgcatt
     6841 tgcgatgaat acagctggat cttcattcca ttcgacgata tccatgtttt cgccttttaa
     6901 ttcattgacg attgcttgaa ctcgttgtcc ctttggcccg acacatgtac cgactgcatc
     6961 gatatttgga tcatttgagc gaactgccac ttttgaacga tcgccagctt cacgggcgat
     7021 gctgacaatt tcaacgattc catcatagac ttctggtact tcttgttcaa ataagcgacg
     7081 caataggtct ggatggctgc ggctaacaaa tacttgcgga cctttagacg tattttctac
     7141 tcgggaaaca taaactttga ttcgatcatg tggttgataa aattcatttg gcatttgatc
     7201 ttgtttagaa agaactgcct caattttacc aagattgaca taaatataac gtttatcctg
     7261 gcgttcgacg attccttgca tgatgtcttt ttcataagca ctgaattcgt tataaataat
     7321 cgttctttct gcttcacgta cacgctgtaa aataacttgt ttagccgttt gcgcagcgat
     7381 ccgtccaaaa tcttttggtg ttacttcaaa acggatcgta tcaccgatct catatgctgg
     7441 attgattaaa agtgcatctt tcaatgagac ttccaactgt gaatccatca cttcttccgt
     7501 tacttctttt accgcataga catggatctt tccttttttc tgatcaaatt ccacttcgac
     7561 gttttgtgct tggccatagt gacgtttgta tgcagaaacc aatgctgctt ctaaagcatc
     7621 gatcacgatt tcttttgaga tccctttttc agcttctaaa gcgtctaacg catttaacat
     7681 ttctttactc atttttttct gattcctctc cgtgattaaa attggatagc taagcgagct
     7741 tttgcaatat tttttcggtc aaaagtcaat tctttttctc gtgtttttat gcgtattttc
     7801 aatgtaagct gttcagcatc aaatgattga agaaatcctt catattgttt ttcgccatct
     7861 actggttggt ataaggagac atggacataa tcaccaagtg ccttttcata gtcgctttct
     7921 tttttcaatg gccgctctgc tcccggggag gatacctcca ggaaataagc ttgaggaatc
     7981 ggatctggat ctgctgcatc aagtttttca ctcagtttct cactgacaaa ggcgcattct
     8041 tcgatatcga taccgccttc tttgtcaata aatactcgta agaaccagct ttttccttct
     8101 tttacaaatt cgacttcgac aagttcaaaa ttttgttcat ctaaaatcgg tgtcaccatt
     8161 tctgtgactg tttcaacgac gctactcaaa agtttcgcct ccttaaaaat taagtgcgta
     8221 attccattaa aaagagtgag cgaaaaatcc gctcactcac agttagtatc attacctata
     8281 agaactatac catactctgc ttaaaattac aagcagacag gaaaacagat gcttatagca
     8341 tatcgaataa cgataattga ttttcatctg gtagatcttt caatacgcca ttgtcgttca
     8401 tatattcgat caatgttttt gaaactttac cgcgggtggc aagatcttct ttggataaaa
     8461 atggaccgtc ttttcttgct tcaacgattt gtttcgccac gttggttccc aaacttggga
     8521 cagctctaaa tggtgcgatc aacgtatcac cttcaataac aaagttaacg gcatccgatt
     8581 tatacaaatc aatcattcca aatttgaatc ctcgttccag catttcattg gctaactcca
     8641 gcactgtcag ttgattcttt tcttttacgg aagcatctaa tcccttgtcc gtgatttctt
     8701 tcattgcttg tttcacagca tcttttcctt tgcacatgga gactagatca aagtcgtctg
     8761 cacgtacaga aaagtatgca cagtaataca aaatagggaa ataaaccttg aaataagcga
     8821 cacgaagagc catcaatacg taagctgcag catgggcttt cggaaacata tatttgattt
     8881 ttgaacaaga atcgatatac cagtcgggca cattattttc tttcatcgcc gatagatagg
     8941 tttctcgcaa ttcatcaggg atcttgttcc attgtccttt acgaacagtt tccatgattt
     9001 taaatgccat cccgctatct aatccagcat ggatcaaata aaccataata tcatcacgac
     9061 agccgattac ttccgccagt gtcgcatctc ctcgtcgaat caattcttcc gcatttccta
     9121 accatacgtc tgtaccatga gatagtccgg aaatttgcag tagttctgca aaagttgtag
     9181 gatgcgtttc ttctaacatc cctcgaacaa aacgagtgcc gaattctgga atacctaatg
     9241 tccctgtttt ggaataaatt tgttcctgac ttactccaag tacttcagga ccggcaaata
     9301 tccgcatcac ttccgggtca tccgtaggga tcgtttgtgg gtcgatccct gataaatctt
     9361 gaagcatccg aataacagtt gggtcatcat gccctagaat atctaatttc aatacattat
     9421 cgtgaatcga gtggaaatca aaatgagtcg ttttccattc tgaattttga tcgtctgctg
     9481 gatattggat cggcgtaaaa tcatagacat ccatataatc gggaataacg atgatccccc
     9541 ctggatgctg gccggttgtc cgtttgactc cagtagcgcc ttttgctaat ctgtcgactt
     9601 ctgcacttcg aaactgcaga ttattgtccc tttcgtatcc ttttacatag ccatatgctg
     9661 ttttgtcggc gactgtacca atcgttccgg cacggtaaac atagtcttcg ccaaacaata
     9721 ctttcgtata gttatgggct tctgcttgat aatcacctga gaagttcaaa tcaatatcgg
     9781 gcactttgtc tccatggaat cctaaaaatg tctcaaatgg aatatcatga ccgtctttgt
     9841 ttaagcgtgc accacatttt ggacattgtt tttctggcat gtcaaatcca gaaccatacg
     9901 taccatcttc aaaaaactcg gaatattggc actctggaca ataataatga ggggctaatg
     9961 gattaacttc agtgattcct gtcatcgtcg caacaaagct agagccaaca gagccacgtg
    10021 aacctactag atagccatct tcattacttt tatgcactag tttttgggcg atcagataaa
    10081 taaccgagaa gccattacca ttaatagaat tcaactcttt ttctaatcgt ttttgaatga
    10141 tctcaggtaa cggatctccg tacatttgtt ttgcttttgt gtaactcaat tctgatattt
    10201 catcttctga acctggaatc ttcggtgtat aaagttcatc tttgactgga atcacttctt
    10261 cgcagatatc tgcgatttta ttcgtatttt ctactacgat ctctttcgct gtttcttccc
    10321 ctaaaaagtg aaatgcagtt agcatctcat cggttgttcg gaaatggaca tccggcaaac
    10381 tatgacgatt caacggattc gctccgccca tagaattgat caaaattttt cggtaaatgg
    10441 catcttcttc gttcagataa tgtacattac ctgttgcaac aacgatttta tccaaacttt
    10501 ttccgatttc taccaaattt tggataattt cttccaaatc atgttcattt tttaccaatt
    10561 cttgctcgat caaaggcgca tagaccgctt ttggcataac ttcaatataa tcatagaatt
    10621 ttgctcggtt tcttgcctct tctacccctt tttgcatcat ggcttcgaat atttctccct
    10681 tatcacaagc tgagccgatc aatagatttt cacgcatctt tttcaattgg gagcgtggta
    10741 ttcgtgggac gcgttcgaag tattcgacat tcgacattga aatcagtttg aacaaatctt
    10801 tcagtcctgc ctgatttttt gctaaaatcg ttacatggaa aggtcgagcc cttttgtaag
    10861 aatctccttc tccgatatgc tcatttagct gatcatgata aagcatgtta tgattgtcca
    10921 ttgcctcttt cacaaagatc catgctaagt gaccagttgc ttcagcatca tagattgctc
    10981 ggtgatgctg ttccaagcta acaccaaact ttttagataa cacacctaat ccgaaacgtt
    11041 tgaattgagg atacagatat ctagctaatt ccaacgtatc aatgactgga ttggccgctt
    11101 caggaatacc ataccttgcg tagctagtat tcaagaaccc catatcaaaa gccgcgttgt
    11161 gggctaccaa aattgtatct tttgaaaatt caaggaacat ccgcaatact tcttcttccg
    11221 actttgaccc tcgaaccatt tcatccgtga taccagtcag atctaccgtt gttcgtgaca
    11281 atggatgtcc tggatcgata aattcatcaa agctttcgat cacatttcct ttatacattt
    11341 tgactgcggc tagctcgatg atcgtgtcat atactgcaga caatcctgtc gtttccacgt
    11401 caaatacgac gtatgtggct tcactcaatg cttcatgtgc atcattataa gcaattggga
    11461 caccatcatc tacgacattc gcttccacgc cgtataagat tttcacacct gctttttttc
    11521 cagcactatg tgcttccgga aaggcttgcg caccaccatg gtctgtaatg gcgatagctc
    11581 ggtgtcccca ttttcctgct tgtgccacaa gatcagagat gctgtttgtt gcatccatcg
    11641 tactcatatt gctatgaaca tgaagctcta ctcgtttttc cccttcagga gcataatctt
    11701 tgcgaggtgt atgtttgact tctatgatat cttgcgcatt catgaccaaa tcacggacaa
    11761 acgtatcttc ttgaatactt cctcgtacct ttaaccagct accgacactg atcgcatcaa
    11821 atacttgttc atctttttcg ccgttcgaga attttttgac gataaatgat gaagtataat
    11881 ctgtgatttt caaagtcaag atcttgcgtt ttgaacgtag ttctctgact tctttgtcga
    11941 atacgtaccc ctcaagtgtg actcttcgtt cttcttcaac gatactgatc attggtgtcg
    12001 ttggttcatc ggctggaata tttcgtccta gctggatggg tccttcaaga gctggcgatt
    12061 gctcttttct ttcctttttc ttttgttcgt ggacaactag actttcagct gcttgcttca
    12121 taaaggcttc tgcctgttct tgtttgcgtt cttcaaaaag tttcaataca cgttccgctt
    12181 gctgctcatc cacttctggt tcgatacgaa attttgggaa tccgtaactg acgaacaact
    12241 cttctactaa tggcaagtat tgttgcttca aataagaaat agctcctgta ctgtcgattg
    12301 gcaagatgac tttacgatct tttatcacag gtacctgcgt tttcaatact tgctgtgcta
    12361 gtggtgtatc gcattgctga ttttccaaag cttgggccca gtaatcttgc aagagctgtt
    12421 catcgaatgt ctggtcatct gctaagatat tcagtttgac ttgtgcaata tctttaaaag
    12481 cgatagtcag atgctgagtc aatgaccgat atagcataat aggcaaaatt ttggaaaaat
    12541 gtagcgtaaa ttcccataaa cgcgatttac gatggaccac tacactatcc atttcaccag
    12601 cagtaagcag tggatgattt ttttctgctt cctctagttg gatttgttcc aacagttttt
    12661 caaataaatc tcgtttttct gacaaagata tacgcccttt ctgatgagaa acaatgcaat
    12721 tgatcgcatc ttatcctctt ctttttcagt accttttagt atactcgttt tttctgagtt
    12781 ttacattaaa aaattggaac tgcgattcaa atcgcagttc caattttaaa agcgaatcat
    12841 cagattgtca aaaacagctg attcagctat ttttattttc tgtgttttaa cgcttattat
    12901 tcgccttggt tcaagaggat tggtaaagta ttcgccaatt cttctttacg tacttcaacc
    12961 atttcgccag ttttcttgat tttcacttct acgattccat ccactgcttt tttaccgaca
    13021 gtgattctga ttggacagcc aatcaaatca gaatccgcga atttcactcc tgcgcgttca
    13081 tttctgtcat caaccagtac ttcatagcca gcttttgtca tcgcttcttc tagttcattc
    13141 gtcaggcttg tttggtattc gtcttttaga ttcatttgga cgatatgcag atcaaatggc
    13201 gcaattcctt ttggccaatt gattccttgt tcatctgaat gttgttctac gattgctgat
    13261 aataaacgac ttacaccgat accataacag cccataatca caaatttttc tcgtccattt
    13321 tcgtctagta cagttgctcc catagattca ctgtaacgag tgccgatttt gaatatatgt
    13381 ccgatttcga ttcctcgagt aaaggcaaga acaccgttgt tgtctggtga aggatctcct
    13441 tcttgtacaa aacgaagatc ttcataagaa agcacagtga aatcgcgttt tggattcaca
    13501 tttttatagt ggaatcctgt ttcgttcgct ccagtaatgg cattcgctaa atcttggaca
    13561 taacggtctg catatacttt tacgtcatct gaaacaccga ctggtccgac agaaccaaac
    13621 tcagcaccta gatatttttg tgcttcttct tctgttgctt cttctaaaaa gtcagcagat
    13681 aaaaagtttt tcagttttac gtcattgact tcatggtctc cacgtaccaa aacaaggaca
    13741 ggttgttcat ccgcaatgaa caatacagac ttgatgattt tttgaggttc aacagaaaag
    13801 aaatctgcta cttcgtcaat tgattttacg ttaggtgtag ctactttctc caattcaagc
    13861 tgtgtttcat gcgatttttt tgatacatag tagcttgtag ccatctccaa gtttgcagca
    13921 taatcacttt cagtcgaata acagatcgta tcctccccga tttctgagat cgccatgaat
    13981 tcctttgagt ctttcccgcc cattgcgccg ccgtctccga tgatcgagcg aaattctaag
    14041 ccacaacgct tgaatacttc ggtataggct ttttcgtaat ctttatatgt ctcgtccaaa
    14101 ctttcttccg ttgcatggaa agaatatgca tctttcatga taaactctct tccgcgaagc
    14161 aaaccgaagc gaggtcgttt ttcgtcacga tatttaggtt ggatttgata aagatttaaa
    14221 ggtaatttct tatatgaatt gatttcatta cgcatcaaat cagtaaaagt ttcttcgtga
    14281 gttggtccaa ggatcatttt tcgatcattg cggtctttga aacgatacaa gtttggtcca
    14341 tatgtttcgt aacgcccgga ttcttcccaa agttctgctg gcaagatggc aggcatcagc
    14401 atttctaccg ctccgatttt ttcaaattct tcccgcataa tgcgtttcag tttttccaat
    14461 acacgatttg ctaatggcag atatgaataa atacccgctg atacttggcg gatatatcca
    14521 gctcttagca agatttgatg gcttaatact tctgcatcat ttggaacttc gcgtaatgtt
    14581 ggaatcaaca tttttgattg tctcattcta tatactcctt tatttcctca aaatagttat
    14641 cgtttgttat tataccctat ttgtcaactt tttctagaaa aagaatcgtt gaatatcgtt
    14701 ccatgtaact agcaccatca acaacattaa aaatccaaag ccagctaatg tcaatattcc
    14761 ttctttttct tgacttaatg gtttcccgcg aatcccttca aaaatattca agactaattt
    14821 cccgccatct aaggcaggaa tcggaagcag attgacgatt ccgagattca ttgaaagaag
    14881 cgccatcaaa ctaataacag ttgttacacc ttgatttgct gcttctgaag acaattggta
    14941 catcatgaca ggtccgccta atttatctaa actgaaacct gtaaatagtg atcctaaggc
    15001 tttgaaaatt tccaatgaac cgctgaaagc ttgacgcgtc cctccaatga tcttatccat
    15061 aaaacctgta ttcattgggg cttttatacc aagttggcca actttttcgc catttgactc
    15121 tacagatttc ggtgtcacgt cgacagattg cacctgacct tctcgttcga tcttaaagtc
    15181 taatgtttta cctggatttt tcgtaatgac tgttgtcaga tcattccatg aatggatttc
    15241 ttttccgtcc acactgacta cctcatcatt ttcttttaag cctgcttctg ccgcagctcc
    15301 attaggcatg atctctccta cgcgattagt gttcgtcact tgaacaccac cttgcataaa
    15361 tgccagaatg atgaataaca cgattgccaa aataaagtta ttcatgggtc cagcaaagtt
    15421 ggtcagcata cgctgccaca atttagccga ttggaactgt acgtcttttg gcgcaattct
    15481 gatttctgtt ccgtcgtttt caataatcgt cgcatcgtga tcaacagggt aggttactac
    15541 ttctgtttcg tctccattca cataaccagt gatagtcagc tcatcttcta aatcataacg
    15601 gctcaattcc atcgggatag catttgtcaa ttggattttc ttacttaaat ttatcttctc
    15661 tacgatgccg tcagaattta gtaaaagaga aagaggcatt cctggtgcca tttctgtttc
    15721 atcatcccca ttgcctgcca ttcgaacata accgccaata ggtaataggc gaagcgtata
    15781 tgttgtcccg tcttttgctt gatgcccata aattttcgga cccataccga tagcaaattc
    15841 gcggacgagg attcctgatc gtttcgcaaa gaagaaatga ccaaactcat gaacaatcac
    15901 taatatacca aaaacgatga taaatgtcag aatcgttttc atagcttttt tctcctttac
    15961 ttgttttttg tgttttttat aaaacaacga taaaacacta taattttacc atagtatacc
    16021 aaagacacca atagtatcaa tataatgaaa aataaaaacc tgcgtctttt atgaaattca
    16081 caaagaaacg caggtatact tactaaataa tgccaaataa atgcatgata ggaaatacaa
    16141 acagcaaact gtcgaaacgg tctaagattc caccatggcc tggtaagata tttcccgagt
    16201 ctttcacatc ataatgacgt ttgattgcag attcgaccaa atcaccaaat tgtccgactg
    16261 ctgaaaaaat aatcgtcatc agaagcatga caaacatacc atgattgaat agttcttttg
    16321 ctgggtatag caataaataa agaaatgcga ctacaacagc actaccgata ccaccgagcg
    16381 caccttcaat cgttttgttg ggcgaaatat caggacttaa cttatgctga ccataacgtc
    16441 gaccaaccat atatgctccg atatcagttg cccaaacaat aaatagacca aatatcaaaa
    16501 cagccaagct ttctgttcgt gcattgacaa aattctggaa acctattccc acatacaagc
    16561 tgacaagcac aggaaaacct gcttcatcaa tcgtatacgt atttttagaa ataactgatg
    16621 ttcctaaaag aatcataact ataagataaa ataacataaa tgtacttaca ttctctggaa
    16681 gaaagaaaaa ccatctttct tttggcaaaa caagtaacac tgcaccaacg gcggataaaa
    16741 ctccttcaaa acttaagagt gtcaatcctt tcatccggaa cagctcgtaa actcctacta
    16801 ccgctaagat tgctgctgta agctcaaccg ctatgcctcc gatccatata atcggaataa
    16861 acaagactag cgccacagct gctgtgatca cacgttgttt catgactgat cccctttctc
    16921 atcttctgtt ttttttacac cgccgaatcg acggtctcga ttttgataag aggcgattgc
    16981 ttcttcaaga tgcgcaccat caaaatcagg ccaaagcgct tttgtaaaat acagctcact
    17041 atatgcgatc tgccataaca gaaaattact aattcgctct tctccacttg tacggatcat
    17101 cagctcagga tcttgtaact ctttaggcaa gaaacctgtc attaaatgct tagcaatcaa
    17161 ttcatcatcg atttcttctg cgtgtatttc tccttttgct acttcttcgg caatttcttg
    17221 gacagcagtc acgatctctg ctctacttcc ataattcaaa gcaaaattca ataccattcc
    17281 agtattgttt tttgtttgct caattgcacg tcttacagca tcttgcgtat gttctggcaa
    17341 tacgttttca taacccatga catgaacttt gacattttct ttaatcaatt ctggtacgaa
    17401 cgtatcaaag aagtcgacag gtagttgcat gagaaaactt acttcatctt ttggtcgctt
    17461 ccagttttca gtcgaaaagg cataaagcgt caacactttc actccaagcc ttgatgcttt
    17521 ttttgtgact ttctttactg tttccatgcc ttctttatgg ccagcaactc gtggcaaacg
    17581 acggttttgc gcccaacgac cattgccgtc catgatgatg gcaatgtgct gaggaattgg
    17641 tccatcggta ttaaattgaa attcgctttt ttcttgaata tatttgtttt tttgcggaaa
    17701 aaaacgtaac attctttttc ctcctatact taaaagattc ccactatctt aagtattata
    17761 gcaatatcta actgtttttc ctatgaaatc attgtttttt tatttaaaaa ctgaataatt
    17821 ttttcttttt ttaattttta aataaaagaa atataaataa aaacagagga agcggaatga
    17881 tccgcccctc tgtttttatg attttattaa acttccaata attctttttc tttatcagca
    17941 gcgatcttat ctacttcttt aatgctgtta tctgtcaatg tttgtacgtc tttttctaat
    18001 ccgcgcaaat catcttcggt aatatcacca tttttttgtt gttttttata ttcatcgatc
    18061 gcatcacgac ggatgttacg aatcgcgatt tttgcatttt ctgcttcttt tttcacatct
    18121 ttagctaatt cttttctgcg ttcttctgtc agttgcggga taactaagcg aatgacattt
    18181 ccatcattgg ttggactgat tccgatatca cttgccataa tagctttttc aacatcttga
    18241 agaatgctct tgtcaaaagg tgtgatcatt aaaacacgtg cttctggaat ttggattgat
    18301 gccatttggt tcaatggtgt tggcgcaccg tagtagttca cagtaatacg gtccaaaagg
    18361 ctagcgttcg cacggcctgc gcggatttgc ccaagttcac gttgaagatt ttgtgctgct
    18421 tttttcattt tttcttttgc ttctgtcata attgcatctg ccatttttat ttccccctta
    18481 cagttgttcc gatattttcg cctaagattg cacggcgaat atttccgtgt tcatttaaat
    18541 tgaagacaag cagtggaata tcattatcca tgcttagtga acttgcagtt gaatccatga
    18601 cttgtaatcc tttggcaata acttccagat gagtcagttc ttcaaatttt actgcatttg
    18661 catctacttt cggatcagca gaataaacac cgtctacatt gtttttagcc atcaggataa
    18721 catctgcgcc gatttctgcc gctcgtaatg ctgctgttgt gtctgtcgag aagtacgggt
    18781 tgccggtacc gcctgcaaag ataacgatcc gtcctttttc taaatgacgt tctgctttac
    18841 ggcgaatata tggctctgcg atttgacgca tttcaatcga agtttgcacg cgtgtcggta
    18901 cacccacgtt ttccaacgta tcctgtaaag ctaaggcatt cataactgta gctaacatac
    18961 ccatgtaatc agcttgagca cgttccatgc ccatttgtgc tccgatttgt ccgcgccaga
    19021 tatttccgcc acccacaacg attgccattt caacgcccag ctcgtgaact tctttgattt
    19081 cttggatgat ttctttgatt actggtggtt tgattccaaa tcctgcatcc ccagctaaag
    19141 cttctccact caattttaag actacacgct gatatttcgg tgtgaccatg ttcattcctc
    19201 caatattttc tattgccatt ttaccatact tagatgattt cgacactcta agactggttt
    19261 ttcttgtttt gcttaaaaaa agggagcgca caaaccgtgc gttcccgtct gttattcaac
    19321 agaattattt tttcacttgg ctcataactt cttctacaaa gttatcttcg cgtttttcga
    19381 taccttcgcc aacttcgaaa cgtacgaatg ttttaacagt tgcgcctttt gatgcaacgt
    19441 atttttcaac agtcatatca ggatctttaa cgaatggttg gtccaccaaa gcgatttctg
    19501 ctttgaattt cttcaagcgt ccttctacca ttttttcaac gatattcgct ggtttgcctt
    19561 cgttcaatgc ttgttctgta agaacagttt tttcatgttc taattcagct tctggaattt
    19621 gtgattcgtt tacataacga ggattgatag ctgctacgtg catagctacg tctcttgcaa
    19681 ctgtttcgtc agttgttcca tctagaacag tcaatacggc aatacgtccg cccatatgca
    19741 agtatccacc aaatgcagca ttgtcgtctt tttctacaac ttcaaagcga cggaagctga
    19801 ttttttctcc gataacttga gttgcttcga tcaagtcaga ttcaattgta cctttatctg
    19861 ttttgatttt cattgcagct tccatgtctg ctggtttgtt ttcagcaaca agttctgcaa
    19921 tttcttttac taaatcttgg aacatttcgt ttttagaaac aaagtctgtt tctgagttta
    19981 cttcaacgat tgctgcagtg ttacctttca cagcaactga agccaatcct tcagctgcaa
    20041 tgcggtcatt tttcttcgca gcctttgcca ttcctttttc acgtaaaaga tcaactgctt
    20101 tttccatgtc gccttctact tcaactaatg cttttttcgc atccatcatt cctacgccag
    20161 tcatttcgcg tagttctttt accattttag ctgtaacgtc tgccatgttt aactcctcct
    20221 gtgtgttttt ctttttaaaa aaagctgctt caaaggagag tgaggcttgt cgcccagcct
    20281 ttgaaacagc tccatcattc aaaattattc tgctgaagaa ttgtcgcctt caacaacatc
    20341 tacgatttct tcgattgatg ttgctgtgtt ttcttctgtg aaatcttctt caactacttg
    20401 atcttcacct tggtttcctt cgatgaaagc atcagccatt tttgaagtaa tcaatttaac
    20461 ggcacgaatt gcatcgtcgt ttgaagggat tactacgtcg atttcatctg gatcgcagtt
    20521 tgtatcaacc atagctacga ttgggatatt taatttgtgt gcttcttgaa cagcaatacg
    20581 ttctttacgt gggtcaacga tgtacattac atctgggatt cttggcatat cagcgatacc
    20641 gcctaagaat ttttcaagac gttcacgttc tttgttcaaa ccagcaactt cttttttagg
    20701 tagaacttca aaagttccat cttcttccat tgcattgatt tgtttcaaac ggctgatacg
    20761 tttttggata gtatcccagt ttgtcaatgt tccgcctaac caacgatggt taacgaagta
    20821 ttgtcctgca cgagttgctt cttctttgat tgcttcttgt gcttgttttt ttgtacctac
    20881 gaataatgct acgccgcctt cttcagcaac gctcttcatg taatcataag ctgcatctac
    20941 taatttaact gttttttgca agtcaatgat gtagattccg tttctttctg tgaagatata
    21001 tttcttcatt tttggattcc agcgacgagt ttggtgacca aagtgtacgc cggcttctag
    21061 taattgtttc atagaaatta ctgccatgtt tgtttcctcc gatttggttt tatttttcct
    21121 cttcttatct tctaccttgc cggcaaactt tttcaagcac ctaccgacaa tccaataaga
    21181 atgtggattt gctgatgcat aaagcaccct cagctattat acagacaaaa gatccgtatc
    21241 gcaagagcaa atatactttt ctgctcaaca ttcaatagtt tacctgaaag ataaaaagaa
    21301 ttcaagaaaa acagtagatt tctctttgtt tctttattat cctttttcca taaaataatt
    21361 ttaggtataa aagacgaata ttattgggca atccttcttt tttttgttat gatacatgtg
    21421 aaatctttcg taaaggagaa agaaaatgcg caaagctcaa agacatttgc tgattaaaca
    21481 agtcattgaa gaattcccga tccgtacgca agaagaacta ttaaacaaac ttgggcatta
    21541 tggcgttacc gccacgcagg caacgatttc tcgagatatc cgtgatctaa aaatcgtgaa
    21601 ggcacctgat gaaaatggcg tttcccgctt cgtattgttt cgcgaaaaag gaactcctga
    21661 gactaggact gaggaagagg atcggctggt tcaaatgatt gaagacattg tattgaaagt
    21721 cgaacgagtc cactttttga cgatcgtcaa taccttgcca gacaatgctc atttatttgc
    21781 atctgtttta gatgagatca aacctccctc tattgtcagt acaattgctg gattcgatac
    21841 gatcatggtc atctcggaaa atgaggagga cgcaaaacga gtagaagaat ttcttcacca
    21901 tccaactgaa gtatcacttt tttaatcaga gcacgtattc ctaatatgga atgcgtgttt
    21961 ttttattttc aatattttcc ttattaaata aacctttaca ctctttacaa aaatacatca
    22021 ttttttattc aattttttca acaccttgat tgaatcacaa taatcatcat ttatattgga
    22081 tgttaacaag agcagcttct tgctctttgt gtatttcaaa aaagaaatga aaggaaatca
    22141 tatgtataaa ttattaactc ctggaccatt gacgacttct gaaacagtga aaaatgctat
    22201 gctgatcgat cattgtactt gggatcaaga atacaaagaa attacacaat ggataagaaa
    22261 aaaattattg gatcttgctc aagtatcgga aggaatatac acaacggtct taatgcaagg
    22321 tagcggctcc tttggggtag aatcggtatt aagttctgtg atcaggccag aagatactgt
    22381 actgatttgt tcaaacggcg catatggaca acgaatgatc aacatgtgcg aatgtctgaa
    22441 actgaactat accgtttatg aggtatcgga acatcaaatc ctccaagctc atgtgattac
    22501 acagctgatt gaagagaatc cctctatctc cgcactagca atggtccata gcgagactac
    22561 ttccggtatt ttgaataatt tggaagagat tgctgctgtc acacaagaaa aagatctttt
    22621 gtttatagtg gacgcgatgt caagctttgg tgggataccg attcgtgtag ccgaactagg
    22681 gattgatttt ttgatttcca gctcaaacaa atgtattcaa ggtgttccag gcttttcttt
    22741 tgtacttgct aataaagcgg aactagaaaa gcgaaaaaat gtgagtcgaa gtttgtcact
    22801 tgatctatat gaccagtacc gcgtgatgga aaacgagaat ggcaaatggc gtttcacttc
    22861 ccctacccat acggttttgg cttttcaaca agcgctgaag gaactagagg cagaaggagg
    22921 aatcgaaact cgatattcac gttatctcgc caataatcat gtactacgac aaaaaatgac
    22981 agagatgggg ttccagcctt tcattcaaga atatcagggg ccattcatca cctcttttct
    23041 ttaccctaag gactggcgat ttgattttaa tcatttttat cagtatttaa agcaaaacgg
    23101 atttgtgatc tatcccggga aaatcagcga tcatgaatgt tttcgtatcg gaaatattgg
    23161 cgagatctat ccggaagata ttttggaact gacagcaatt atcaaagact ataaggagaa
    23221 cgttaatgat taaaactgta atttttgatt gggcaggaac aactgtggac tttggctgta
    23281 tggctcctgt ccacgctttt agaaatgctt ttctagaaaa aggaatccaa ctgactgaca
    23341 aagaaatccg cgaaccgatg ggaaaattaa aatgggatca tatccaacag cttctttccc
    23401 tcccttctgt caaaaaacaa tggatagcta tttatggaca actacctcag gaaaaagagg
    23461 tggaggaatt gtatcaacaa tttgaacatt atctgtttaa agatttggtc aagcattcta
    23521 ccttgaaacc cgacacattg gaaacgatcg aacggttgag aaacgctggg atcaatattg
    23581 gttccacgac tggatttact gctcctatga tgacaatcgt agcagaaacc gcaaaaaaag
    23641 aagggtattc accagacttc atggcaactt ctgaagacgt cgaagggtat ggtcgaccgt
    23701 ttccttatat gatccataaa aacatgcagt acttcaaaaa caagtcggtt gatgaagtaa
    23761 tcaaagtcgg agatacggtc tcagatatcc aggaagggaa aaatgccgga gtgttgacag
    23821 taggtgtaat tgaaggtagt tcgctaatgg ggatttctta tgatgagtac caaaaattag
    23881 agatggggaa aaaagatcgt ttaaaacagt ctgttgctct tagattccaa caagctggcg
    23941 ctgatatttg tgtaaacaat ttaaaagagt taacagaata cattttgtac gctgacaaga
    24001 atccagaatg acttttatac aaaatcagag gtcgtgaaaa agctgtactg catcaagtaa
    24061 taagaacagc caaacaaaaa tagctcctca tatttttcgt ttggttaggc ttattaccgc
    24121 agatgcaagc ttttgaacac cgtttattcg aaaaaaaaag ggagctgtga cacgactttt
    24181 gtcacagtcc ccttatttac aaacaaacag tgtttaagag acaacctctc cactaaacgg
    24241 tgttcattca gctgactctc ggtatttgct caaaaaacga taaaatttga aaagctattt
    24301 tctcttttgt ttctctaata ctcggatcag aacgctgatt tcacattctc tttttcttac
    24361 atcttatctg gtgcatgaag tcctagcaaa cgaaggtctt ctttcaataa tacagtcact
    24421 gcataaacta gagctaagcg tgcttctttt tgttcatcat cagctaaaat cttcgtatga
    24481 gcatagtatt tgttgaatgc ttgtgctaat ttgattgcat gtttcgcaat cactgacggt
    24541 tcgtattttt ccccagcaga caagaccgtt tcagggtatt tttgaactaa tttaaccact
    24601 tcccagctgg tatcgtcatt caatgcatag tctgctgttt ctgaagggac aaatcctgct
    24661 ttttccaaca ggctgactgc acgagcatgt gtatattgca cataaggtcc agtttctcct
    24721 tcaaatcgaa caacttcttc caggttaaag tcaaatgtat tcagtcgatc gtttttcaaa
    24781 tcgtggaaaa tgactgcccc aaccccaact tgtttagcta cagcatcttt gttttccaaa
    24841 tcagggtttt tctcgctgat ttgttcttta gcagattgga ttgcttcatt taatacttct
    24901 tctaataaga cgatctttcc tttacgagtt gataattttt taccaccttg cgtgatcaaa
    24961 ccaaatggaa tatggcgcat atcgtcagac cagtcaaagc ccatttcctt caagacagct
    25021 ttcaactgtt taaaatgata gctttgttca ttccctacta catatagaga ttgtttgaag
    25081 tcgtaagtac gtttacggta caatgcagca gctaagtcac gtgtaatgta tagtgtcgca
    25141 ccgtctgact tcttaatcaa cgctggattc aggtcataag cagataggtc aacgatctct
    25201 gcacctttat cctcgttcag caaatgtttt tcttctaaaa gtttgacgat ttcatccatc
    25261 ttgtcattgt agaaagcttc accgttcaac gaatcgaaac gtacttccag cagatcatag
    25321 attttattga attctttcat cgattcatca cggaaccatt gccataattg aatagcctct
    25381 tcatcgcctt cttccagacg tttgaaccaa gcacgagctt cttcatttaa ttctggttct
    25441 gtttcagcta cttcatggaa ttggacatat aaacgaagca attcattgat tggttctgct
    25501 ttaacagctt cttctgtacc ccattttttg taagcgacga tcagttttcc aaactgtgtt
    25561 ccccagtcac ctaaatggtt gatgcggatt ggctgataac cgattttttc cataatgaaa
    25621 ccgatcgaat taccgataac tgtcgaacgc aaatgtccca ttgagattgg tttggcaata
    25681 ttaggagaag acatgtcgat tggtactgtt ccttgattcc cgatattgct atccccataa
    25741 tgttcttttt ctttcactac tgtttgcaaa acttttttgc tgataagttc tttattcatg
    25801 aaaaagttca agtaaggtcc gacaacttcg attttttcaa agttggcaga atcgattttt
    25861 tctgctaaat ctgcagcgat ttgctgtggc gcttttcggt aaacttttgc taatgaaaag
    25921 gctggaaatg caacatctcc gtgttcagct gattttggat tttctagtaa ttgttcgact
    25981 tgttccagtg ttaaatcatc tttgacagcg tcatagacag cttttgcgac aagatcttta
    26041 ttattcatct ttattcctcc taaagtgctc ccttgattgt taaacaaaaa aaatctctag
    26101 cgacggcata cttagtatgc catcactaga gacgagattt cccgcggtac cactccaatt
    26161 gtcctaaaaa aggaccagct ccatctgata tcggtagacg accgtctgtt taaaacagaa
    26221 ttctccaagt gcgcttcgtt gtatcttctt cattcggctt ccaccacttc cgaattcgct
    26281 agccaagaat gatacaagta ctctcttgtt caacaaatct tagtcttatt aaactttctt
    26341 gaattatatc agaaaaaaaa acgaaaggct agtcgtttct gataaaaaaa caatccagat
    26401 ggcctaaagg agaagaaata ccacctggat agctataaat catttcgtaa atacgaaaga
    26461 cttaacaaat taatcagcta cgataatcgt tccttcttca gaagctaaaa gattctcgat
    26521 attttctaaa gaagtgatga ttgccttagc gtttggtttt gcttcaacaa atgcaatagc
    26581 tgcctctact ttcggaagca tgcttcctgg agcaaattgc ttttcatcaa tgtattgttt
    26641 catttctgaa acagtaacag tttctaattt cttttgatct ggtttttggt aattgacata
    26701 cacattgtct actcctgtca atacgatcag caaatccgca tcgatgattt cggctaattt
    26761 ttctgaagca aaatctttat cgattacggc ttctcgtcct tctaatccag tagctgtttc
    26821 tacaacagga atcccaccgc caccaacaga gactgtgata actccttgat cgaccagcgt
    26881 ttcgatgaca cgtgcttctt taatcgagat gggtttaggg gaagcgacta cttttctcca
    26941 tccacgtcca gcatcttctt tgaatgtcac agtggagtca gcattcattt gttctttggc
    27001 ttcttcttcc gtgtagaatg gaccgactgg tttacttgga tttttgaatg aaggatcatt
    27061 ttcatccaca ataacttgag tgactaaaga aaccacatct ttatcgatcc ctttttcctt
    27121 cagtacttcg cccatggcat tttgtaacca gtaaccgata gatccttctg tcattgcaac
    27181 acatgtatct aaaggcattg ccggtgtttt ctcagaatca gcagcttgct gctgaatcaa
    27241 taggttaccg acttgcggac catttccgtg ggagatgatc aattcatctc cttgttcgat
    27301 aaatttcact aaatactttg ctgtttccat taacgcttct tgttgggctt ttgcacttgc
    27361 atccgtagac aagattgcat taccccctaa agcgacaact acttttcgtt tggccatttc
    27421 attcgtcctt tcttcagttc taccgaattt tctagataac aaaacgagcc agcgttttgt
    27481 gattttccct caatgctgac tcgttttttc gtgagatgaa tgtggttatg cttaaacgcg
    27541 agggataaac aagttaccta atgttgctgc catgatcgct ttgattgagt gcatacgatt
    27601 ttctgcttgg tcaaattgac gagcatattt gctgcggaag acttcatctg ttacttccat
    27661 ttcagtgatg ccaaagcgtt ctttcatttg ttcaccgtaa acagtgtttg tatcatggaa
    27721 agctggcaag cagtgcaaga agatcaaacg atctgtgttg tgtgtttttt ctaccatttc
    27781 catattgatt tggtaaggtt tcaacaattt gatacgttct tcgaatttat cttcttcacc
    27841 cattgatacc catacatcag aataaaggac gtctgctccg tctacacctt tatcaacatc
    27901 gtcggtaatc atcaattgtg caccggattt ttcagcaaag ccttctgcca ttttgacgat
    27961 ttcttcttca ggttgtaatt cttttggtgc aacgatacgc atattcgctc ctaaaattgc
    28021 acctgtgact aataaagagt tagccatatt gtttcgacca tctccgcagt aagcaacagt
    28081 gataccttct actgttccaa agttttcttg gatagttaaa aagtcagcga tcatttgtgt
    28141 tggatgccat tcatcagtca agccattcca aactggaaca ccagagaatt ctgctagttc
    28201 ctctaccatt ttttgactga atccacggaa ttcgattcca tcaaacatac gacctagtac
    28261 tttagctgta tcttctgtgg attctttttt acctaattgg atatcatttg cacctagata
    28321 ttcaggatgt gcacctagat cgatcgctgc agtagtaaat gcagaacgag tacgtgtaga
    28381 tgttttttca aataaaagcg caatattttt tccttctaga tagtgatgtg ggataccacg
    28441 ttttttcaag tctttcaagt gttctgaaaa atcgatcaaa tattgtaatt cttcttttgt
    28501 aaagtctttt tctgctaata agcttcttcc ttggaatact gattctttca tattaaacat
    28561 tctcctttag attgttttta tttaagatta aagaggaaat cccgacggca gctgacagta
    28621 agaccgccgt caggaaacaa attacttcaa gtcttcacgg acaagtggtt ggctcatgca
    28681 gcgtggacca ccacggcctc gtgacaattc acttgaattg atttctaaca ctttgatgcc
    28741 atagctacga agcaattcgt tcgatacata atttcggtta taagtgacta caacacctgg
    28801 agcgattgcc aatgtgtttg atccatcatt ccattgttct cgaggtgcaa cgatctcatc
    28861 tccattacca gttgggatca gtacaagatc atctaatcca agagcagctt tcatcgtttc
    28921 gtgtaagtta tctgaatgag taatcttgat atcatcacca tctggttcga ttgtaaagac
    28981 atccatctta ccgtctttac tttgaattgc tggatggata gtgaatttat cgtgatctac
    29041 cattgtaaat acggtatcca aatgcatcat tgcacggttg tttggaattt tgattgctaa
    29101 cactttttca aatcctgaat tttttgcgaa taggtggcgt gctaattttt ctaaagcttt
    29161 cgcattagtt cgttgagaaa tcccaacagc tactacttta tcgcttaaga tcaattcgtc
    29221 tccgccttcg atatgatctg gattttcacg atccaaccat acttcgattc ctttatttgc
    29281 aaatcttgga tgatgtttca aaatatattc tgtaaacatc gattcacgac gacgtgcttc
    29341 aaaagtcatc ttattgactg tcatcccatt tcccattgat gcggaagggt cgcgtgtaaa
    29401 gtacaagttt ggcattgggt ccatgtaaaa tggatagtca tcgtctgctg acagatcgta
    29461 tagactgcta gaacgtactt caatatcttt tgtacgaacc ccagccatga ttttatctac
    29521 catttcttgc gtttccattg atagaaggaa ctcatgaaga ccctctctta cagcattcga
    29581 tgcaatatga gattcatcca acattttatt caagaattgt tctttgacat tgcctgcgtc
    29641 aatcgcttct gccgctaatt tttccaagta aagagtctcg acgccttcat tttgcaatgt
    29701 ctttgcaaag ttgtcatgtt cttcttgagc aatcggaaga tatggaatat catcgaacaa
    29761 cagacgatcc ataatatctg gtgtcaaatt ttccacttct tgtccaggcc ttttcagtaa
    29821 aactgtcttt aatttcccta tttcagagaa aacgtgaata ggtttatcca tgttgtgttg
    29881 cctccttctt tttgattaca tgtataggat atcctccttt tgtaatcact ttcataattt
    29941 tgtctcattc aaaatgagac attcctcaca ttaatattcg ataattaaat aattaaacgt
    30001 ttttctattt ttaagcgtaa tttattcatt ttttattctg tatacacttt caaaaaaata
    30061 tttattcatt gaaaaaaatt ttttgaataa attaaaaaaa taaattatat tagcgttgtt
    30121 agcgtttact atatgtatta ttgttgtttt ttatacacaa atcattcgct tcaaaacaaa
    30181 ttattcaata ccattgtata ttttttacat aataacaaat tatatttgta aagtattaaa
    30241 acttgtttct aatgttggta tgttaaaact ttacaaattc tttaaaaaaa gtgacaataa
    30301 atatagtgaa caataaggag aggacttttt aatgcgtgtt aataaaatcg attttcactt
    30361 ttcaaaactc agatatcaac ctgattttga acatttctcg gatgaagagt tccaacagat
    30421 caaggaacat actgttcttc gttcttataa aaaaggacag atccttttcg acgatggtga
    30481 tcccagacaa cggttgtata tcttgaccaa aggactcgtt cgtttagaac gttatgatga
    30541 aagtgcaact tattactact atgactatgt gaatacaaat aacctttttc ctatgtcagg
    30601 aatgtttgga gaagagacct acacttatac agctcaagcg atgactgata ttgaaacatt
    30661 ctaccttcct gtttcctact atgaaaaatt agcacgaaaa aatcccgaac agttgatcta
    30721 tatgatacaa aaaatttcta aagtagttga aatacatgaa ttgcgtatcc aaatcggatt
    30781 gacctctagc gcctttgacc gggtaaaaca aaatttattc attttgaaag aagaattggg
    30841 cgtaccaaca aaagatggtc atatcaccat tccttatccg atcaccttaa aagaattagc
    30901 agtgaatagc ggcacgacac gtgaaactgc tggacaagta atcaaacaac tacgtgattc
    30961 cggactgtta gattatgaca aaaagcgttt tactttctgt aagacagcta ctactccagc
    31021 tatgagagaa taacgcgaac aaaaataagc agtgaccctg atatttatca gggtcactgc
    31081 ttattttcct ccctaaaact tctgaaagat ccggcagttt tagatcactg ggcaagactc
    31141 aaagattttc tatgtgtgtt tcagttatgt aatattcact gtttgcaaaa aatactgata
    31201 gattaactag aggaagcgtc ttgtcctcat ccgacctaga ttattcgata ttcctcgaca
    31261 ataaacgatt aatcagtgag ggcaatcaga ggaacggata atgatgaata agctgtaaaa
    31321 aatagggctt tgacaaaagc gtgtcacagc ccttatttcg attaaacggt gtgtacctgt
    31381 caactcttcg gtcacaagtc ataatgttca taaacatgag gagctgtttt ttgaaattgt
    31441 tccttgtgaa tcagagttaa acgacaggct tacgaactct tgattaaacg gcgttcaaaa
    31501 gcttgcatac gcggtaataa gaacagccag gtcaaaaaca tgagaagccg tttttcctgg
    31561 gctgttctta ttacttgatg cagggcagat ttttcacaac ctctttattc agataaaacc
    31621 aagcttggat cagcattcaa ctgatagcta gcaaaatttc ttttttgcat ttccacatgt
    31681 gctgctgctc caatcattgc agcattatct ccacaaagtc gaagaggggg aatcactagt
    31741 tctacctcag ggagtttagt tgccaaagca tcctgcaatc cttcacgcaa cccttgattg
    31801 gccgctacac ctccagctac aatcagttgc ttgactggat aattttgaca agctcgaagt
    31861 gttttagtaa tcaatacatc gatcacactt gcttgaaagc tagctgctaa atcatttttg
    31921 tctagatctt ctccacgctg ttgtgcatta tgcaccaaat tgataaatgc actttttaat
    31981 ccgctaaaac tgaaatcata attatcttca tggatcatcg ctcgtggaaa atggtaatta
    32041 tcttttccct gatgagctag ctgatcgatt tcttttccgc ttgggtaaga aagacctaat
    32101 actcttccaa ctttgtcata agcttctcct gctgcgtcat ctcttgtctc cccaatgatt
    32161 tcatatgatc catcttcttg catatagact aattctgtat gtcctccgct aacaagaagt
    32221 gccatcaatg gaaactggaa tggtttaacc agacgggctg catagatatg ccctgccata
    32281 tggtttacag gaataagcgg caattggtgt gcccaagcaa aagccttagc tgcagaaata
    32341 ccaatcagca acgagccgac aagtcctggt ccataagtga cagcgactgc cgataaatct
    32401 tctgccgaca caccagcttc taccagtgca tcttccaagc ataaggtgat ttgttctacg
    32461 tgatggcggc tagctacttc aggaactacg ccaccaaaac gtttatgact gtttatttga
    32521 gaagcaacga tgttagataa gatctctgtt ccatttctaa cgaccgctac actcgtttca
    32581 tcacaacttg attcaatcgc cagaatcaat tcttcattca tttcatcgtc tccgttttta
    32641 actttctgct cataatgatc gcatcttccg tcggattgcg ataatatgat ttccgtttac
    32701 ctaatatacg aaacttttct gattcataaa gttttcttgc tgcttcatta gatagacgta
    32761 cttctaaaaa aacatgcagc gaatctttta tttgttccgt aatcagtaat tgtaacaaat
    32821 gccgtgcatg cccttttcct tgttctgaaa ctgcaacagc aatatttgtg atctcgactt
    32881 catctattac tttcgagtat ccaataaagc cacagatctg gttatcttca actaaaagca
    32941 gataatcaga gtgaggctgt tggatgtctg ccaaaaactg cattttcgtc caaggtgaac
    33001 catgtggata agcattttcg ctaatcatcc atacgcattc tgccaagtac gcttcatcaa
    33061 aatctttttt tctgcaaatc aactaatctc actcattttc taaaagtttt atcatatcca
    33121 acgcatcttc ttttgtttca gtgtaatatc tttttttgat cgttgttgct tgaaaaccta
    33181 acttccgata aagtctttgt gcatcttgat tactcatacg cacttctaat gacatcgtct
    33241 cacagcgatt cattatagca aagttctcga tttcgtcaat aagcagcgaa ccgattcgtt
    33301 tacgctgata tgccggtcga acggcaatat tcgtgatatg gcaatctaaa ccgaacgctc
    33361 ttgaaccgat aaaaccaatc attcttccat tatcaaagat acctagatat agatgaggaa
    33421 gcggtgactt caattctgat ataaaggcac tttttgtcca tggcaattcg ccattataga
    33481 cttctcgttc gacatccagc agctctttga tatcttctgt agtcaattct cttagtacgt
    33541 aacgacgatc gatttgttcg attgtttttt ctgtataaat cattttatct tgaaaaaagc
    33601 ttctggcata cgctctaaat tttttcaaca taactttcgt ctccaggtgt gtgcgtctcc
    33661 aaccattttt cttctgcttc tacccgtttt aaatagcgag gaagaaaagc ttgtttctct
    33721 gcaactggtt cagctaaagc acctaattga gccacagtta caccacttgg aatatcccat
    33781 gctggaactg tattaatcat cgcactaggc aatatttcct ttatttcata gaagaatttg
    33841 tgacaatcac tcccgacgaa ataaatagct tcattcagct tttgtagttg tgtgaacaaa
    33901 tcagaagcag aaatatgtac atcttcaagt acaatttcta atctattttc tttccagcgg
    33961 tatgccccag cgtatacatt ttttcttcga gcatcaaaca tgggcacaat aattttatcc
    34021 acaccgatgc aattagccgc gatggttttc agactagata ctcctactag ctctttatct
    34081 aatgtataag caatcgtttt tgctgtcgtt acacctatac gaagccctgt ataagaaccg
    34141 ggaccatcag aaaccgcgat tcggtcaatg tcttttggac ttatttgaag atctgcaaac
    34201 aattggtcga ttgcaggcat cagtgttaca ctgtggttgc gtttgatatt tgtttgtatt
    34261 tgtccaagaa tttgttcgtc ttctaccaca ccgatcgcca aagtttggtt tgcagtatct
    34321 attcctaatg taatcatata tttgatcctt tctgctatga cattctcgcc ttccattgta
    34381 gcatactttt ttattctgag gatgaaaata ccaaaggcaa aactagtaca atgatacatg
    34441 attatctgct ggcgggcaaa ttttgcccct tcctgaaaca caaaaaagct gcggtatcac
    34501 ttcatttccc cacagctttt ccatctttta tttcgttgat tctcgaataa tcaactctgt
    34561 ttccacaata atctttcttg aaaccggtgc tttggaatta cttaattgaa gaatcgtctc
    34621 cactgctagc tctcccatcc attcggtata aacttttaca gtagaaagag agggcgttac
    34681 atatttcgct acactgacat cattgaaacc catcacagaa atatcttctg gtaccactaa
    34741 acctttttct tgaatcgctt tcagtgcgcc aatcgctaat gcatcattag ctgcaaaaag
    34801 cgcatcagga acatgcggat tcgtttttaa atactgcttc actgcttgat atcctgactc
    34861 gacagaaaaa tctgcttcga taattggacc ttcgtcgtag cctttttctg ccaaaacttg
    34921 ttgaaatgcc ataattctgg gatcttttag ccgctgatgg tttttcttcg tatattctgt
    34981 tccagcaagc atagcgatat gttgcgcttt atgggagaca aaatgttcaa tgactttttg
    35041 aacacttgac ttaaagtcga caactagaga gtcgattcct tgagaagtgc cgtcagaatc
    35101 taccaaaagc aaggcatttt gggatccttt catttctaat aactgagctt cgtcgaattt
    35161 tcctagtgcg atcgttccat ctgtcggaag atcactaatg gaatcccacg tttctttcaa
    35221 taaagtaacg tttgcttctt ctgccttttt ttcgattcct agacgaatag ataaataata
    35281 aagatcttca agctcttccg tatcgtcgta ccactggatc aggcgaagcg tttgcttagt
    35341 atttgctgca tttttacgat gtttcgtata atttaagcgt tctgctgctt caaaaatttt
    35401 ttgctttgtg gctaagccaa cggaaagatc aggatcatag ttgagaactc ttgaaacagt
    35461 agcaggagaa actcctgcca actgcgcaat gtctttaatt gttgccattt gtctctcctc
    35521 cttttttacg tttataaaat tgcagtaaat cgttcaaacg ctgcctgtcc tttttcatct
    35581 cgcttgaata ctccagcgtc ttccagtaca cgtgcaaaaa cctgacctac agatttttgt
    35641 acgacatcgg tgaccgtatc tttcgtcaaa tcaggatgtt ctttttttaa ttgttctgcc
    35701 cacggacgat gatattcagc catctggttt tcttctccta ataagaaatg ctctacttct
    35761 actagttctg gtttcaaacg aggtggtaaa acagcaagcc ccattacttc gatcaaccca
    35821 atgttctcct ttttgatatg ttggacatct ttatgtggat gaaaaatccc atcaggatgt
    35881 tcttctgaaa cattgttgtc tcgaaggaca aggtccaact caaagtaatt gtcccttctt
    35941 cgtgcaattg gcgtaatcgt atggtgtggt gtaccatctg ctgaaaaagc tctgatagat
    36001 actgtttcat ccgaatatgc tttccacttt tccaatactg agttagctgc ttcaatcaac
    36061 aattttttct ctgttgattg caaacggatc acagacatcg gccatttcac gactcctgcg
    36121 atgacttgcg gataatctgc tagtttgata agtttttcta tcggtgcttt tgccatagga
    36181 aattcatgac gtcctgcctg ataatgatca tgagaaagaa tcgatcctcc aacaatcggc
    36241 aagtcagcat tcgaaccaac aaagtaatga ggcaagactt cagtaatccg aagcagtcta
    36301 gcaaatgttt cctttgtgat tttcatcggg cggtgttgtt ctgataaaat gatcgaatgt
    36361 tcattgtaat aagcataagg agaatattgg aatccccagc tttcaccgtc tagattcatt
    36421 cgaataatcc ggtgattggt gcgggctgga tagttcaagc gacctctata tccttcgttt
    36481 tccatgcaaa gcatgcaggt aggatagtct acttttaccg cctcgcgttc tgctgcgatt
    36541 tgttttggat ctttttctgg cttagataaa ttgattgtga tttccagttc accatactcc
    36601 gactctgccg gaaatttgat gttttttgcg atggctcttg ttttgatgta gtcatttttc
    36661 ttacttaaat taaagaaata ctcagttgct tcctctgggc ttttcgaata gtgctgtgca
    36721 aagaatgcat tgacgactga aggtggcggt gtgagaaaat ccattaattg cgcttcaaaa
    36781 atctcttgtt ctgctggcaa ttctgaaaga acaccatttt ctcttgcctt agcgacaagc
    36841 tgatccaata agtctacaga ttcttcctta actggtctta cttcaatgct ttctagagca
    36901 tcttctccta ccatccctaa aagacgattc tgtaaatata agcggtccat ttccatccat
    36961 ccgccagctt cgatcgcaag tgtggcaaaa tcacaaatcg tttgactgat tgacatatct
    37021 cattccccta ttcttcataa ccatttggat ggctgacatg ccaatcccat gctgttttga
    37081 taattgcttt gatatctgtg tattcaggtt tccaacccag aacctctctc gctttttcac
    37141 ttgaagcgac taatcggcta ggatctccag ctcttcttgg tgctatttct gctggaattt
    37201 cttttcctgt cacttctcta gctgcttcta gcatttcctt gactgagtat cctttgctgc
    37261 tgcctaaatt gaagaagttg ctttcatttc cttctttcaa gtattccaaa gctaaaatat
    37321 gtgcagcaat caaatcttct acttgaacat aatctctgat acatgttcca tctggtgtat
    37381 cataatcgtc tccataaaca gccaatgctt ttctttgacc aagagctact tgtaaaatga
    37441 ttgggacaag atgcgtttct ggtgtatgat cttctccgat agatgcatct gcttttgctc
    37501 cggctacatt gaagtagcgc aaagcgacat agcgcatgcc atatgcttgg tcacaccact
    37561 tcatcatttt ttccatcatc aatttacttt caccatacgg atttttagga ttagctggtg
    37621 tatcttctgt gattggagac tcttttggtt ctccgtaagt tgctgcagta gaagagaaca
    37681 cgattttatt cacattgaac tcgtgcatga cttcaagtaa gatttgcata ccgtatacgt
    37741 tgttgttgaa atacatcaat ggtttttcga cagattctcc tactaaagag cttgcagcaa
    37801 aatggattac tccttcaatc ggttcctttt caaatacgga acgtagaaat tctttatccc
    37861 ggatgtctcc ttcataaaaa tgagcatctg gatgtactgc ttgtttgtga cctgtgagca
    37921 aattatctac cacagctact tgatacccct tttgaactag ctggtctaca gcgtgcgaac
    37981 cgatataacc ggctccgcct agtactaaaa ttgtcataaa aaacactcct ttgattagta
    38041 aaattgtgtt tgttgattat atataattta aaaaaacgaa gtttactttt atggtgaaaa
    38101 caaacaaagt aaaatttcgt aaattcatat ggtaaattta taataaaaca tttagtaaac
    38161 attttcaagg attttttgca aaggtttaca aacaaacgta aaactagcct ttttttctct
    38221 tttgttccat aatagatata acaaataata aatgaggtgg attcaatgaa aaaatttgta
    38281 tctggaatat tagtaggaag tctggcaaca gccgctgccg ttgctggttt ggtcgcttct
    38341 gtgaaaaaaa cagtgatcga tccaattgac gaaaaagaag caatgatcga agaaaaccgt
    38401 aaaaaagcaa tgcgcaaacg cgtttctcgt taataattat ttaaaaacac gcatgaagac
    38461 ttgtgaaaga acagataagt catcatgcgt atttttattt gtcagtcaat ataagttgtg
    38521 ctattttatc tgcctgtctc agattccatg gatctgtata aggtctagct actgctgcag
    38581 ttagccaatc cacaccttca acaggtattc catagcaata aaagtcagac tggatttccc
    38641 ctgaagcatc aatcacgcga ttcgtacctc gctcaacatc tatagcttct gaatgataac
    38701 ttcctgtatt atctgaaaat gaaaaagggc gaacaagttt gttttccttc aaatttttta
    38761 tgacaggatt acttgaacga gaaaagcttg tttgtggcaa tcgagcttca atcaaatagc
    38821 gactgctgat ttctttatct tgtagagaaa taacatagcg gttgtgcttt tgctgaatat
    38881 caaatggcgg ttcgaacaaa tgaaaaatac ccgcatctat cagtgctgct aattctttcg
    38941 tccgaatgac tggcggaccg atcgttaaaa agctatttag atgagtaaac catccccata
    39001 gtatttcttt gtattccttt gcagaaaaaa cgtgccattc aatagcctgc cggattggat
    39061 cacgccagtc ttttaatgca tcaaatgttg aagcaaatgc tcctgtgcaa ttgccttttt
    39121 ccgcttcttt tatctgccct tcaataaatg ctcggctagc ttctgcaaag gactcatcct
    39181 gataggtaag aggaatttct aaatacgacc aatcccatct ataagggatt agtgctggat
    39241 gctttccgag acactcctct gaagagaggg agagaaaatc atgctcaaaa tttttctttg
    39301 gaatcggcaa atgatattct tcgatgattt tcttgtaata aaacaactca acgtcttttt
    39361 tcagatagtc aaaaaatgtt tcgccagtca aaaatcccga ctgatgccat tgctccaggt
    39421 tttcttttgt tagtaaccgt ggccatgcca ttgatccgcc ttgcttttgg tttcttcctc
    39481 gagggtaata agggagcccc cttcttgatc cactgtatac aatcggttcc ttgcctgatg
    39541 gatgatagac aagttttcct ttttcgttct cgaagcgccc ttctcttgat actgtaaaca
    39601 atccgacata atcaaaaaaa cttaagccta gacctcttaa aaagacattt tctttaggcg
    39661 gtatcttcga aagatcgaca tctgcaggat tagaaggaag ctgatacagt aaatcatttt
    39721 tctttgcgta gtctacccac actctttctt cttctgtctc atcattttcc cagtgaccgc
    39781 ttgctaaaac aagctgatcg atagaatagc tttgctgatc tgtctgtaaa agataaccat
    39841 cttttctttt gctgactttt tttactaaag aataaacaaa ctgaatagaa gctggaaatt
    39901 cttcttgcaa ctttgagaaa aaccagcgtt gatagagtcc gtataaacat cgagtagatt
    39961 gctgatcttt ttccagacga ttgatttctt ctataattag ttgcttattt ttggttaccg
    40021 tctgttcgat ataatctgta gcaggtcctt tactccattg aaacaagttg ggtccctgtg
    40081 ttaccaatcc tccactggac aatgtttcat ctgtaaaaag cgtcacttgt tgagaaacag
    40141 aattcattaa taactccggt ggctgattca accgccaaac tcgacctcca ggaccattgg
    40201 gatcgaaaag aaaaagttca agagaatgtc tgtcctgatt attatggaga atcctttctg
    40261 ctatacttaa tcctctaggt ccggcaccaa tgatccctat tttcatttgc atgcctccat
    40321 ttcgataaat tttttcaata aaacagcatg gttctgatgt tcattttttg caccataaac
    40381 aaaagtaatg actggatgtt ctttcataag ttgactgagt ttaaaaatag cttgcttctt
    40441 ttcttcttcg aaaatcaatt cttgctggta tttctttgca aatgaagcaa atcgttctgg
    40501 tacatggtca aaagttttgc gtgcttcatt actaggtgca atttctttca accacagatc
    40561 taactgcgct ttttcttttg aaattcctcg tggccagaac ctatccacga gtattctata
    40621 gccatcctct ttttcagcat caaggtaaac acgttt
//
LOCUS       DAYNVV010000018        39818 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.018, whole genome shotgun sequence.
ACCESSION   DAYNVV010000018 DAYNVV010000000
VERSION     DAYNVV010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39818
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.018"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(369..1487)
                     /locus_tag="ACGXWR_001121"
     CDS             complement(369..1487)
                     /locus_tag="ACGXWR_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802718.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1720..1842
                     /locus_tag="ACGXWR_001122"
     CDS             1720..1842
                     /locus_tag="ACGXWR_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802719.1"
                     /translation="MHLIMIFSLLSIISLFAFSASRLLDAETQPIPVKVRKNDR"
     gene            1958..3265
                     /locus_tag="ACGXWR_001123"
     CDS             1958..3265
                     /locus_tag="ACGXWR_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HFK0802720.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            3384..4583
                     /locus_tag="ACGXWR_001124"
     CDS             3384..4583
                     /locus_tag="ACGXWR_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFK0802721.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(4610..5878)
                     /locus_tag="ACGXWR_001125"
     CDS             complement(4610..5878)
                     /locus_tag="ACGXWR_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HFK0802722.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     regulatory      complement(5933..5999)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            complement(6041..6687)
                     /locus_tag="ACGXWR_001126"
                     /pseudo
     CDS             complement(6041..6687)
                     /locus_tag="ACGXWR_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FusB/FusC family EF-G-binding protein"
     gene            complement(7095..7598)
                     /locus_tag="ACGXWR_001127"
     CDS             complement(7095..7598)
                     /locus_tag="ACGXWR_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFK0802723.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(7721..8485)
                     /locus_tag="ACGXWR_001128"
     CDS             complement(7721..8485)
                     /locus_tag="ACGXWR_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HFK0802724.1"
                     /translation="MKEIQSVKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLAEVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSSTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            8592..8867
                     /locus_tag="ACGXWR_001129"
     CDS             8592..8867
                     /locus_tag="ACGXWR_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HFK0802725.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            9583..10536
                     /gene="yidC"
                     /locus_tag="ACGXWR_001130"
     CDS             9583..10536
                     /gene="yidC"
                     /locus_tag="ACGXWR_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0051205 - protein insertion into membrane
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HFK0802726.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGGAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVIMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAAKPADNKQATKQIKQPKNSTNNKGRNAGRQQKRK"
     gene            10658..11867
                     /locus_tag="ACGXWR_001131"
                     /pseudo
     CDS             10658..11867
                     /locus_tag="ACGXWR_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012008915.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(11912..12312)
                     /locus_tag="ACGXWR_001132"
                     /pseudo
     CDS             complement(11912..12312)
                     /locus_tag="ACGXWR_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723846.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(12559..12993)
                     /gene="tnpA"
                     /locus_tag="ACGXWR_001133"
                     /pseudo
     CDS             complement(12559..12993)
                     /gene="tnpA"
                     /locus_tag="ACGXWR_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005576373.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(13171..13537)
                     /locus_tag="ACGXWR_001134"
                     /pseudo
     CDS             complement(13171..13537)
                     /locus_tag="ACGXWR_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387104.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            complement(13551..13836)
                     /locus_tag="ACGXWR_001135"
                     /pseudo
     CDS             complement(13551..13836)
                     /locus_tag="ACGXWR_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
     gene            complement(13845..14036)
                     /locus_tag="ACGXWR_001136"
                     /pseudo
     CDS             complement(13845..14036)
                     /locus_tag="ACGXWR_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(14036..14512)
                     /locus_tag="ACGXWR_001137"
                     /pseudo
     CDS             complement(14036..14512)
                     /locus_tag="ACGXWR_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290865.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
     gene            complement(14980..15333)
                     /locus_tag="ACGXWR_001138"
     CDS             complement(14980..15333)
                     /locus_tag="ACGXWR_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802727.1"
                     /translation="MAMSEKAKKYLKEIKGAKTIPELKDVEIAIKRDGILAWAEFTKL
                     NEAVEEKKVALRKKKQETSLQEILFWAYKKESDKLLKMMDEGADKDAIQMQVQRYDSI
                     GQIIAEADLEDEYEV"
     gene            complement(15461..15871)
                     /locus_tag="ACGXWR_001139"
     CDS             complement(15461..15871)
                     /locus_tag="ACGXWR_001139"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802728.1"
                     /translation="MEEIMQMILGNAKFQLGQVVSTPAVLETFNPLQTANGIPEALSN
                     LWFRQEISIAEIEDAVLDAKNGKELANSLNRIKLFRKFTLDRELDGMVRLKGTDVWKN
                     ISYLKVYTATPPKKPTPPRFQSNGWSLFFSHKSA"
     gene            complement(15949..16074)
                     /locus_tag="ACGXWR_001140"
     CDS             complement(15949..16074)
                     /locus_tag="ACGXWR_001140"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802729.1"
                     /translation="MAGITGVNVIVTYNHHLPIQCLDFSCNYYYIELVIPQKSAS"
     gene            complement(16263..17129)
                     /locus_tag="ACGXWR_001141"
     CDS             complement(16263..17129)
                     /locus_tag="ACGXWR_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFK0802730.1"
                     /translation="MEELFSNALKSVKSNRVLYTASFFARSSLLYLQEIGQLTALKAH
                     TSRRTGLSSYLCFLVEVGSGTLEYKGQKYTLQVGDMVFIDCLKPYVHESSEDDLWTLR
                     WCHFNGIGMTEVYKKYLERGGQPVFKTSKTDKYADLLRSLHMVAEGQEYVRDMKINVL
                     LSELLMHLMEDSWNPDKVPNFSTKKMELQNIKQYLDDHYTEKITLDQLSAEFFINKQY
                     LAKIFRETYGTTVVGYLNQKRITQAKHLLRFTNLSMEEIATKIGITDANYFSRTFFKV
                     EGVRPSEFRKMW"
     gene            complement(17153..18805)
                     /locus_tag="ACGXWR_001142"
     CDS             complement(17153..18805)
                     /locus_tag="ACGXWR_001142"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFK0802731.1"
                     /translation="MNYKVEYERWLNHANADIIEELRSYSEKDIEDSFYKNLSFGTGG
                     LRGTIGAGTNRMNVHTVGKASQGLADYLNKNYEAASVVVGYDSRIKSDVFAKTAADIF
                     AANGIQVHLWPELLPVPTVSFATRYLKADAGVMITASHNPSKYNGYKVYGADGCQITT
                     EAATAILAEIEKLDIFADVKMDGDASKIASIQSEVLTAFIEEVKGQSVLFGEEVDKNV
                     AIVYSPLNGTGLVPVTRTLAEMGYSNVTVVEEQRLPDGNFPTCPYPNPEIKEAMSLGM
                     EYAKKYNADLLLATDPDCDRVGIAVKSAHGDYVLLSGNETGLLLLDYICSQRIKHGKM
                     PADPVMVKTIVTMDLGERIASNYGVRTIDVLTGFKFIGEQIGMLEKAGKVDSYIFGFE
                     ESYGYLSGSYVRDKDGVNAAYLICEMFSYYKTQGISLLDKLNEIYTKYGYCLNTLHSF
                     EFDGAAGFTKMQEIMVEFHKGLDIIGGKKVIETLDYSKGLNGLPKSDVLKFMLEDNCS
                     VVVRPSGTEPKLKTYISVSAENKEAAEAMEAIMAAELAEMFE"
     gene            complement(18810..19604)
                     /locus_tag="ACGXWR_001143"
     CDS             complement(18810..19604)
                     /locus_tag="ACGXWR_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I phosphomannose isomerase catalytic
                     subunit"
                     /protein_id="HFK0802732.1"
                     /translation="MTLTEVLQEHPEFLGTHPQTKGELPILIKFIDAKKDLSVQVHPT
                     DEYAIEKENGQLGKTEMWYVLDASLIYGLQKITEEAVIREAIAQGTVERYLQKVPVKK
                     NDVFFIEAGTIHAIGAGALIAEIQENSNLTYRLYDYDRVDKNGKKRELHVDKALEVAN
                     LKGLSEPKQPLRVLKYRAGVAAELLCRCKHFEVSRMIVNTERRQTVHYRADSISFRVL
                     LCVNGCGTVRFDNESLDIYKGDCLFVPADSTEISIHGSIQFLDVRG"
     gene            complement(19796..21109)
                     /locus_tag="ACGXWR_001144"
     CDS             complement(19796..21109)
                     /locus_tag="ACGXWR_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HFK0802733.1"
                     /translation="MNIVLLSGGSGKRLWPLSNDIRSKQFIKIFKTEDGYESMVQRVY
                     RQIKKVDNDATVTIATSKTQVSAIHNQLGEDVGVSVEPCRRDTFPAIALATAYLVDVM
                     GIDPEESVVVCPVDPYVEDDYFEALKSLSDQADKGEANLVLMGIEPTYPSEKYGYIIP
                     ESAEQTAFVNTFKEKPSEAVAKEYIAQGALWNGGVFVYKLKYVMERAHQLIDFVDYQD
                     LFNKYDTLTKISFDYAVVEHEDKIQVQRFAGMWKDLGTWNTLTEGMEESIIGKGVMNE
                     NCDGVHILNELDVPVLAMGLHDVVICASREGILVSDKEQSSYIKPFVDKFEQQIMFAE
                     KSWGSYKVMDVEAESMTIKVTLNASHSMNYHSHKNRDEVWVVLAGTGKTIVDGYEQVV
                     KAGDVITMSAGCRHTIMADTELKLIEVQLGKDINVKDKQKFELEY"
     gene            complement(21177..22121)
                     /locus_tag="ACGXWR_001145"
     CDS             complement(21177..22121)
                     /locus_tag="ACGXWR_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014424865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthase family protein"
                     /protein_id="HFK0802734.1"
                     /translation="MMEKDAKIYVAGHRGMAGSAIVRELNRQDYNNIITRTHKELDLC
                     RQDAVEAFFAQEKPDYVFLAAAKVGGIIANQNALADFMYENMILEMNVINSAWENGCK
                     KLQFLGSSCIYPRMAPQPMPESCLLTSELEKTNEAYALAKISGLKYCEFLNKQYGTDY
                     ISVMPTNLYGPNDNYHPTHSHVLPALIRRFHEAKEAGLPTVTCWGDGSPLREFLYVDD
                     LANLCVFLMNNYSGDETVNAGTGKELSIKELTEMVAKVIGYEGEILWDTSKPNGTPRK
                     LLDVSKATKLGWTYKTELEDGIRLSYEDFLNNPMRAER"
     gene            complement(22158..23243)
                     /locus_tag="ACGXWR_001146"
     CDS             complement(22158..23243)
                     /locus_tag="ACGXWR_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFK0802735.1"
                     /translation="MNKHICFYLSSHGFGHIARNLPIIMATLCRCEAKITLVCGANHL
                     DFAKRNLEQELPKELIDRVRYRPINTDIGLINREGTLLVDTGKLTEICEYFLAKVPSL
                     AKTEAEWLKREAVSAVLCDMPIWAMDACDMAGVPFLYVGNFTWTELYREFLPEHIWKE
                     YAKRYGKIQHTMLYALNNEEMLEFLQNSEKTPTSVVARPIHNDEVQRIKSQHEKPPVF
                     VALGMSARFKQPIDVSHAPYDFITTLGVPLVGENVTVISNSTPNTQDYIAAADYVITK
                     AGWGTVAECILAQRPMALFARDTVLEDRTTICKLQKLGLAISVTPENLHRVERVIEDL
                     KQLDTSNFDTFYDAASEIADKLISLMQ"
     gene            complement(23251..24297)
                     /gene="gmd"
                     /locus_tag="ACGXWR_001147"
     CDS             complement(23251..24297)
                     /gene="gmd"
                     /locus_tag="ACGXWR_001147"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008446 - GDP-mannose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0019673 - GDP-mannose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HFK0802736.1"
                     /translation="MKKALITGITGQDGSYLADFLLEKGYEVHGITRRASISNTARID
                     HLMGKITLHDGDLSDSSSLIRIISIVQPDEIYNLAAQSHVQVSFDVPEYSGDVDALGV
                     MRILEACRILGLTKKTKIYQASTSELYGKVEEVPQRETTPFHPYSPYAVAKQYGFWIT
                     KEYREAYGMFAVNGILFNHESERRGENFVTRKITLAAGRIAEGLQDHLELGNMDSLRD
                     WGYAKDYVECMWMILQHETPEDFVIATGEQHTVRDFTEKAFAANGMTIRWEGTGIDEK
                     GYDVETGKMLVCVNPQWFRPTDVDNLWGDPTKAKTVLGWNPQKTSYEELVNIMAKHDR
                     ELAKREAAMKNAVK"
     gene            complement(24569..24928)
                     /locus_tag="ACGXWR_001148"
                     /pseudo
     CDS             complement(24569..24928)
                     /locus_tag="ACGXWR_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612146.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(24935..26398)
                     /locus_tag="ACGXWR_001149"
     CDS             complement(24935..26398)
                     /locus_tag="ACGXWR_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
                     /protein_id="HFK0802737.1"
                     /translation="MQGVIAMMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFE
                     FIYPIVEATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYS
                     FEEKIPPFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNLYLDSTHIKANA
                     NKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPE
                     SGYYVKGEREKQFAYSVHTSCDDNGFILSTIITPRNIHDSQVAFQLVKQSKRLFPEIN
                     CVVADAGYKTPKFVHFLTHLNLRPCLPYSRPKGKKELLSKNEFLYDEYFDCYICPQDQ
                     MLAFSTVTREGYREYKSNPKECVNCPLLNQCTISKNHQRVITRHVWGDLMDEVEHLRL
                     TDLNKSIYKKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLVFAAMNLKKLATW
                     LWKGKEPLFFCSKIRNEVDKKLFQARVTSLEQLLSTV"
     gene            27032..28003
                     /locus_tag="ACGXWR_001150"
     CDS             27032..28003
                     /locus_tag="ACGXWR_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFK0802738.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
     gene            complement(27980..28069)
                     /locus_tag="ACGXWR_001151"
                     /pseudo
     CDS             complement(27980..28069)
                     /locus_tag="ACGXWR_001151"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
     gene            complement(28081..28317)
                     /locus_tag="ACGXWR_001152"
     CDS             complement(28081..28317)
                     /locus_tag="ACGXWR_001152"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFK0802739.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(28286..28417)
                     /locus_tag="ACGXWR_001153"
     CDS             complement(28286..28417)
                     /locus_tag="ACGXWR_001153"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFK0802740.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            complement(28493..28876)
                     /locus_tag="ACGXWR_001154"
     CDS             complement(28493..28876)
                     /locus_tag="ACGXWR_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFK0802741.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            complement(28909..29694)
                     /locus_tag="ACGXWR_001155"
     CDS             complement(28909..29694)
                     /locus_tag="ACGXWR_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFK0802742.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            29872..30972
                     /locus_tag="ACGXWR_001156"
     CDS             29872..30972
                     /locus_tag="ACGXWR_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFK0802743.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            30962..31786
                     /locus_tag="ACGXWR_001157"
     CDS             30962..31786
                     /locus_tag="ACGXWR_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HFK0802744.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            31783..32598
                     /locus_tag="ACGXWR_001158"
     CDS             31783..32598
                     /locus_tag="ACGXWR_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0802745.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            32595..33425
                     /locus_tag="ACGXWR_001159"
     CDS             32595..33425
                     /locus_tag="ACGXWR_001159"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0802746.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            33432..34463
                     /locus_tag="ACGXWR_001160"
     CDS             33432..34463
                     /locus_tag="ACGXWR_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802747.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(34570..35843)
                     /locus_tag="ACGXWR_001161"
                     /pseudo
     CDS             complement(34570..35843)
                     /locus_tag="ACGXWR_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            36070..36138
                     /locus_tag="ACGXWR_001162"
                     /pseudo
     CDS             36070..36138
                     /locus_tag="ACGXWR_001162"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
     gene            36120..36329
                     /locus_tag="ACGXWR_001163"
     CDS             36120..36329
                     /locus_tag="ACGXWR_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802748.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            36280..36999
                     /locus_tag="ACGXWR_001164"
                     /pseudo
     CDS             36280..36999
                     /locus_tag="ACGXWR_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010745868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
     gene            complement(36997..37517)
                     /locus_tag="ACGXWR_001165"
                     /pseudo
     CDS             complement(36997..37517)
                     /locus_tag="ACGXWR_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            37805..38458
                     /locus_tag="ACGXWR_001166"
     CDS             37805..38458
                     /locus_tag="ACGXWR_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFK0802749.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            38455..39774
                     /locus_tag="ACGXWR_001167"
     CDS             38455..39774
                     /locus_tag="ACGXWR_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFK0802750.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
BASE COUNT        11606 a         8263 c         7943 g        12006 t
ORIGIN      
        1 ttttttaaac ggtgttccag aagtagcttc ttcggaaata agccgaaatt tcacaaaaat
       61 ttgagaaata atttttgtca atctcttctt atttcttgaa gctgaccact tctgtcacaa
      121 cctcttcctt aaacggtgtt caaaagcttg catctgcggt aataagccca ccaaacaaaa
      181 aatatgaaga gctatttttg cttgctgttc ttattacttg atgcagaaca gctttttcac
      241 aacctctcat acacggtgtt taatcagctg accttcggta ttagctcaaa aaacggaaaa
      301 atatgtgaaa ctatttttcc gtttgtttct ctaatactca ggtcaaaaca ctgatttcac
      361 aacctctttt aataacgaag aatcgctgtc agactctttt catctggcgc atctttttga
      421 tccaaaataa acactttccc gccattaatg atcacatcat ctgctaatgc attcaacact
      481 tgacgccgat catattctgt ttcaggatct tcaccgaaac catcagctaa gtttgacgta
      541 gcgataaata aatgtgacac ttttccttct ttcgcagctg gaacgatatc aactaactga
      601 tcgatgaatt tcttatctaa gagtttattg tattcttttg attcttgagc tgcgagttca
      661 cttgacagct tcttcgcccc ttcttcgata tctctaaagg atagctgcgc aggagaagca
      721 gaaatcgcaa cgtctgcaca ataataggga tttttagcaa tttttttgaa catcgtctga
      781 ttttctggta atgcaaataa ataaatcggc cattgttcag gattttcgaa agaatccttc
      841 aagtacgtat caacagcttg gtaatagttg acccaatcga tctctacttc ttcatctttt
      901 ggatttacgc catggaaagt tactccatct cgggctccgc ctcctccatt agaagagaag
      961 ttcaaaccgc cacctgtcag ttcagatccc aatgcagtaa cgacatcaac cggtgcccct
     1021 tctggtagag atacttcttt tacttgtttg ttgctgacct catacaattt catggagtcg
     1081 cggttcaatc ccaataaata ataagaatag ttgaactgcc catttttgat aatagccagt
     1141 aaataaggaa gatcacttac atagtattga tcgtctaccg ggatactcaa acgatggata
     1201 taggtctggt cagcagttat aatgaccgct acactcgtag ttgcactacg ccaaaacgaa
     1261 ggatctccta acaaattttc aattttttct tggaacgggg accagtcatg ttcggaatat
     1321 tttttctcaa aacgtttctt tgcttctttc gcaaaatttt tgaatttgat ctgatctttt
     1381 tccacatctt gatgggcgac atgcgtattc agcatgatcg tgacgaatgg tcctttagcg
     1441 ccttctgaag tcaattgtgt caataattct ttatcctttt ttgccataaa cgtacccctc
     1501 ctaaaaaaat cattcctttg tttctatcta aagtctacca caacactatt tttccataca
     1561 ataaaacgta tctaaaaaaa taaaacggtt tctacggttt taaatttagc tattttttta
     1621 agttatcttc ataatttcct caattattta gccccagtct tcaactattc ttcatgaaat
     1681 gctgataaac taagaaaaag aataaaagag gtggatctta tgcatttgat tatgattttc
     1741 agtttattaa gtattatcag tttatttgct ttcagcgctt cccgcttatt agatgcggaa
     1801 acacagccta ttcctgtaaa agtacgtaaa aacgaccgct aaacttccat aacgcgcgtt
     1861 cttatcctaa agttttttca gaaacattga aactctctcc cctctctgat aaaattttaa
     1921 tttgtagcga aacaaattaa ttacaaggag atcggatatg tccataaaaa aaacacgtct
     1981 agtcctatta ttggctagtc tcattctttg ccttgcttct tttctaccag ctgttgctgt
     2041 gcaagctgaa gatacgttca aagtaaatgc aaaagcagct tttgctgtag atgcgcaaag
     2101 cggtaagatt ctttatgatc aagatggaga aaaaaccatg gggatcgctt caatcacaaa
     2161 aatcatcggt ctttacatcg tccttgatca agtaaaagaa ggaaaactgt catggggtga
     2221 taaagtttcg atttcagatt atgcagaaaa tttgagtatc accccagatt tatcgaatgt
     2281 tcctttgcat aaagaaaaca cctacactgt caaagaatta ttcgactctg caatcatcca
     2341 gtcagccaat gcttcaatgg tggccttggc agaaaaaatc tctggcagcg aagctaaatt
     2401 cactgaacga atgaaagaac aattgaaaga ttggggaatc aaagatgcaa caatcgttaa
     2461 tgcatcagga ttgaacaact cttatcttgg cgaaaaccga ccagaaggca ctggagaaaa
     2521 cgacgaaaat caaatgtctg ctcaagatgt ggccatcgtt gcccgccatt tgatcttgga
     2581 tttcccagaa atactggatg tatcaagtac tacgacccaa atgtttggcg aaaatacgca
     2641 atcaccagtg gaaatggtca actggaactg gatgctccca ggattcgtta attacaagga
     2701 aggcgtggac ggattaaaaa ctggtacgac tgagcttgca ggtgcttgtt tcgttggtac
     2761 gatcactaaa aacgatcaac ggatcatcac tgtcgtattg aatgcggacg gccatgcgga
     2821 aaacccgagt gcccgcttca atgaaacaga ccgtttgatg gactactgct atgacaattg
     2881 gtcagaaaaa gagctcggaa aagctaacgc aagtattcct agtctaaaaa ccattgatgt
     2941 aaaagacgga aaagaatcaa cagttcctgt tgtgcttaaa agccctgtaa aagtatgggt
     3001 acgaaacgat atggatactg gcaaattaac gatcacgcca acacttgaca agaagcaagt
     3061 cactgacaat gagatccaag cacctatgga taaaggtaca aaaatcggta ccgctacgat
     3121 caccttggca gacgataaat taggctattt agaagacaac aatgcaccat caacagagat
     3181 cattacggat aaaacagtgg aaaaagcgaa tatattcgtg attggctggc gacgcgtcgc
     3241 agaatttttc ggcaacttgt tttaattgaa caataagaaa aacatctttc catcggaaag
     3301 atgttttttt gctttttcta gtttaaataa cagctttttt catctatttt cgttatactg
     3361 tataagaaaa aggagttgaa tttatgaatc taaccagaga tctgatcttt ttagttctct
     3421 atcttattgg ggtattctct atcgtttatt ggcgaaaaca gaagaaggat ccttccttgt
     3481 tcttttacgg cagtacgtgg acatttacgg taatcttaac ttattttgtc gtgttggaaa
     3541 ttttttattc gaccttttat tttttgattc cattgttgtt ctttagtatc tttgcttttt
     3601 cttatttcac agaaaaacga aggctactga atggtctttt attcaatgtt ttactcatca
     3661 gtttcggcat ctacttgttt gtcttgctgt atgaaacgca aaatattttt cttggcggac
     3721 tgatcgcctt gatcacgatt ccattgctac ttgtcctttt atttggtatt tatggattga
     3781 ttgtttttct tttttggaac ggggtcacag ttttacgtag agaatcgcat tcattagcta
     3841 atcttttaac gttgatacta gccatttttc ttacactgtt tcttgttttt gactttttct
     3901 tgttaaaata tttgccgcaa tggataaatg ctttgttttt ctgcgttccc ctgatcttga
     3961 tctatctatt tatcgtattc tacaactttt tgactgtctc attcttgtat cagttcaacc
     4021 ggcctcgata caatcaagac ttcatcgttg tgttaggcgc tggattgatc aatggagaaa
     4081 cagtttctcc tcttctagcc aagcgaatca ataaggcaat tgctttttat cgggctcaaa
     4141 gccgtgctac attaaatccg cccatcttat tgatgtctgg cgggcaagga gcagacgaaa
     4201 aagtaccaga ggccattgcg atgaaacaat atgccatgga acaaggaatc cctgaaagag
     4261 acattcttgt cgaaaccaat tcgacaacca ctttggaaaa catgctctat tcaaaggaaa
     4321 tcatggatca gcaaatgaaa gggccatacc gcgcgatctt tagttccaac aattaccaca
     4381 tttttagagc cggtctttat gcgcggcaag ccaaattgaa agcaaatggt attggtgcaa
     4441 aaacagcttt ctactacttg cctaatgcgt ttttaagaga atacctcgcc atcttgatga
     4501 tgaacaaaaa aagacatatg atcatttgcg gattgctttt cgcaggctcc gcattcttat
     4561 cgctgattac tttacttttc taaaaaaaca aggtgtgaca aaacatatgt cacaccttgt
     4621 ttttttcttt cattctctta actattggca aaaagagtat cccttttttg accgctactt
     4681 gctgagcaga ataaataccg ctgttgcctg aacacataaa gctgatcaag cagatcataa
     4741 agaagtatac tgccgcttgt gaaccgaaca attcgatccc catcacaaag caggcaatcg
     4801 gtgtatttgt cgcaccagaa aatactccga taaagcccaa tcctgcaaga aaaggaacag
     4861 aaacatggag caaaggcgct agtgctgcac caagcgttgc accaatttca aacaatggtg
     4921 tcacttctcc cccttgatat cccgcgccta aagacaaaac tgtgaagaat aacttcccaa
     4981 taaaatcata gacatgtgcc tgtccattaa atgattcttg aagtaacgga agactcaatc
     5041 cgagataacg ttgtgtttgc aaaatcaatg ctgctgccac aactacagct ccacctatcg
     5101 tatttcgaca aacaggatga ggaatccatt gtgcatatcg cgcttttaaa aagacgatcg
     5161 aacggctgaa tacccaacca atcaaaccaa aagcaatccc agcaacaaaa actttgaaga
     5221 acagcaacat actccattca ggaatcacac ccatttggta atgtagatga gaaacaccat
     5281 agctttctgt catgaaattt gcaaacagtg cagcaaagaa gctagggaag atcgcttctg
     5341 ttcggacttt cccgattgcc aacacttcta atccaaataa tgttccagct aaaggtgtgc
     5401 caaatacaga actaaaaccc gcactgattc cactgataat caagatttcc cgttctgatt
     5461 tatccaatcg gaacaaacgt gccgtattat ctgctaacgc tccccccatt tggactgctg
     5521 ttccttcacg gccaacagat cccccaaata aatgggtagt tatggttcca aacagtgtaa
     5581 gtggaataag ccgcaacggg attttttctt ctccaccatt tccttgatcg atcactaagt
     5641 tgtttccacg actagaaagt ccgccgtgat acgcatagag ataagcaaaa agcgcaccac
     5701 taactggtag tagacaaagg agccaaggat gtgatagtcg gatatctgtc acaactgtca
     5761 ggctatttaa gaaaaaagca gacaagctcc ccatgaatat accgagaatc gctgtgatca
     5821 ccagccactt cagcatatac actaaaatgc gtactggact cggtaattgt ttttccataa
     5881 aaaattcctc ctcaataaaa aaacgcctac taaagaaagg ggctgtcccc agactttagt
     5941 aggcgtcatt agctatcttt cgttagcatt taaaggcgaa caccatcacc tattcacttc
     6001 cattaaaaga tagcatattt ttctgtaaaa aacaataaaa ttatcgttct ttctttacac
     6061 gttcagcaaa ttcatagaaa ggagccaatt tcgttaactg ttgattacat tggtcactat
     6121 catgacaaat ataattcccc tttttcgtat acgtgccatc agaacctgct ttcgttgtag
     6181 aaagaaaaag cgaaacattc gatgttttct gacagattgc acagattccc ttatttatcg
     6241 ttggtgataa agtaccgcta atccctttta atttttcatc ttcgtaatag accatgaatt
     6301 ttttctgcgt acctggatca ttccagccga tgtacgtatg ttcttgcaag tcgatttcat
     6361 tccaagctgg ttgtttgagt tttttcactt ttcggaataa tttctcgatt tgtggtttgc
     6421 taggctgcat aaacggctga acgatttgct tcagctcctc caatgctctt tctgcttgcg
     6481 cttttgtcag ttttacgtct aaaactgtcg ttaaaaatgt atcgattctg gcagttcgtg
     6541 atctaatatg tctcgaatct tttcagctgc tagtgcctga actgtttgta ccgtttttgg
     6601 atcattgaca gatgagtacg catttaataa ctgttctact tctcttatta taaaaaaata
     6661 ttggtatggt tttattgttt gttccatgat tttaaagtcc tttcttctaa ccaaagtgca
     6721 tactttgtag aaaaaagtga tcttctgcaa agtatgtgtt acctgaagat cctggactct
     6781 tttaaataag atacgttttg catcttatca tcaccccctt taatgcttat tattctatgt
     6841 acatgattca ttcgataaat aaaagtaaac cgtatcttga acagatagtc aactgcaaac
     6901 agaaaaaagg actgtgacaa aagtcgtgtc aaagtccctt gtttcgaatg aatggtgttc
     6961 aaaagcttgc atctgcggta ataagccgaa acttcacaaa aatttgagaa gtaattttcg
     7021 taaattcctt cttatttctt gaagctgacc acttctgtca caacctcaat atggtctatt
     7081 attggtttta cctgttaaat cgaggattct ttcccaaagt aacgttgcca tctcttacgc
     7141 atacttgcag acatgggctg agccgcttct ttgactgcgc agtatttgtc cacgaatgtc
     7201 acaatatatc cttctttata cttaggcggt gcgatcgttg caccccacat gtgcttcaaa
     7261 atgatatctc gctcaagatc cgacaaatcg gtgatttttt ctgcattctt tacagcaatt
     7321 cttggatgga tatacgcatg tgtcccctcg tcaaatttcg tcgtacgcca atcatagtag
     7381 aacagatcat gcaaaagtcc agcacgcgct gttgctttag cattgccacc ccattttttt
     7441 gcgagcagat aactatagta agaaacactg atggaatgct ccaaacgagt ggaatgaaca
     7501 tgctgtgtgt aattcgctaa ttttttcact gcttctgttt ctaaaagatc ttgtacataa
     7561 gacatatatt cttcgtcttc acgccatttt tctgtcataa ttatcgattt gccacctttt
     7621 tgaatttcat tttcttctga aattgatcta agtataccac cagtgttcgg attattctag
     7681 tcgctctaga taaaatagct aaagcttaat agttccttaa tcataaagaa aaatgataaa
     7741 gaacgatccc tgctgcgact ccgacattca atgattccgc atttcctttc attgggatat
     7801 atacgttctg atcagtcgaa gacaagattt cctgacttac tccctgacct tcgtttccca
     7861 tgattatagc gaaatcctct gttttttcta ctttgtctaa tgcatgtgct tcttcattta
     7921 attctgtacc gtacaccgta aaccctttgc ctttcattac agggatcact tctgccaaat
     7981 ctttttgtaa cacaggcaaa tgataattgc ttccctgcat gcttcgcagc acctttgtac
     8041 tataaatatc tgccgttcct ttacctaata aaacaccagc cataccaaac gcatctgccg
     8101 tacggatcat cgttcccaca tttccaggat cctgtacatt atctagtaaa agccagcctc
     8161 ctgaaaaatc tggcgtatct tcagatgtta acgtcatcac tgctaagatc ccttgcggtg
     8221 taggtagatc tgacatagcg gtcatgacct catctgaaac tagaaaagta gaaatctctt
     8281 tgtttacagc cagccagtct ccccattctt tcatacctct ctgtgtcaca aaaagttctt
     8341 ttatttctgc atcagacgac gcagcttctt cgatcagatg gaacccttcc aaaagatatt
     8401 ctgccttttc ttctctgtat ttctttttat gtagtttttt taattctttg attcttggat
     8461 tttttactga ttggatctct ttcacattcc tcacctcaac tgattatatc atggaatagg
     8521 tgcttgagct tgtttcatcc taaaaaaatc ggtatcattg atttataaaa caggaaagaa
     8581 aggtgacgaa catgcgcaaa gttaaaatga atgtccaagg acgtgtccag ggcgtgggat
     8641 ttcgctatat gaccaagatg gttgctgatc agttaggcgt gaccggaacg gtaaaaaacg
     8701 aagacgacgg ctcagtcaca atcgaagcaa tcggaaatga cgacatcatc caaaaattta
     8761 tcgaagaagt caagaagtct ccgagcccaa gtggacgagt gcagtatgtg gatgtccaag
     8821 aagatccgat gattgaggaa cgaaagaaat ttgatgtggt gggataaggt tgtttttgaa
     8881 gcgctttgcc tcgagtatta aggagaaaca ttttccaaat agcttctcat attttgaaat
     8941 gtaatgactt aataccgaga ggcagctgat aaaacaccgt caataaggtt gtgaaaaagc
     9001 tggtctgcat caagcattaa ggactggttg tgaaaaatag ctctccatat ttttcaacag
     9061 gctggactta atgccgtaga tgcaagcttt tgaacatcgt cgataaggtt gcgaaaaagc
     9121 tgatctgcat caagcattaa ggactggttg tgaaaaagtc gcttagtttt gagtattaag
     9181 gaaaattttg tgaaaatggc tttccacatt tttgcataaa tttgacttaa taccaagaaa
     9241 ctgacttttg aacatcgtcg ataaggttgt ttttgaggca ctttgcctca agtattaaag
     9301 acaggtagta aaaaagctga tctataactt gcaataaatt tgcttaaccc atattttcca
     9361 gacagaacaa aaaagttttt agttttttaa ataagaaaga aacacttgga atcactcttt
     9421 tctttctaag tatttctttc ttgatttttt gtcttttttc aaaatttttc gctacgaaaa
     9481 agaacgaata tttatatgaa atttctatga agttgattga attccatgcg cttttttagt
     9541 atagttaagt ttgtgtaaaa attatagaag aggaagtatt ctatgaataa atggaaaaac
     9601 tggttattgg gatccggact tgtcagtatc ctgctctttt tatctggctg tgtgcggatg
     9661 gattcaaacg gaaaccctga cacttcagga atcgtttatc gagtactcgt ccatcctatg
     9721 ggccaagcga ttacatatct agttgagaat ttcaattggt cttacggctg ggcagttatt
     9781 gcaatgactg tgatcgttcg tatcatcatc ttgccactag gtatcagtca atcgaaaaaa
     9841 acaatgatcc aatctgaaaa aatgcaagcg ttaaaaccac aagttgaagc agcacaacaa
     9901 aagctaaaag ctgcaacaac acgtgaagaa caaatggcag cacaagcaga aatgcagcaa
     9961 gtatatcgcg aaaatggatt gagtatgacc ggcggaatcg gctgtctgcc tctattgatc
    10021 caaatgccga tcttctctgc cttgtatttt acggctcgct acacagaagg tatccgtgaa
    10081 tcatcttttt acggcatcga tctaggctca ccaagtatgg tgcttgtggc catcgcaggg
    10141 ggcgcttatc tgcttcaagg atatatttca acaatcggta ttcctgaaga acagaaaaag
    10201 acgatgcgta cgatgctgat cgtctctcct gctatgatcg tcttcatgtc gatcagtgcg
    10261 ccagccggtg ttacacttta ctgggtagtc ggtggtgtgt tcagctgtct gcaaacattc
    10321 atcacaaacg ttataatgaa accgcgtttg aaagcacaag tggcagaaga gttgaaacaa
    10381 aacccgccaa aacaagtcgt tactccaaga aaagacgtga cagaatcagc agcaaagcca
    10441 gctgacaaca aacaagcaac aaaacaaatc aaacaaccaa aaaacagtac aaacaacaaa
    10501 ggccgcaacg caggaaggca gcagaagcgg aaataaaaat atatgacaaa aaactgtaga
    10561 caaataaaaa aatttctttg ttctacagtt tttttgttac aattaaagaa aacgttcgca
    10621 tttcgaggag gaatgtataa tgatgtccaa ataatcaatg tatagtcgaa tggaagaaga
    10681 caaaatttcg ctagatgcac ttgttcctaa aaatcattta gtccgtaaaa ttgacaaatt
    10741 attgtcattt gattttattt atctcattgt tgaatcaact tactcgacca ttggtcgccc
    10801 tagcgttgat cctgtcgtct tagtaaaatt agtattcatt caatatttat ttggaatttg
    10861 ttcgatgcgt cagaccatta aataagttga aacaaaccta gcttatcgtt ggtttcttgg
    10921 gcttagttta attgataaag ttcctcattt ttcaactttt ggtaaaaact atgcacggcg
    10981 tttcagagaa accgatttgt ttgaacagat atttatcatt attctcgaat aagcagttga
    11041 tgctagattt attcatgaag aaattttgta tatggattca actcatatta aagcgaatgc
    11101 gaacaaacgt atttttacaa gagatatggc acataaagaa gccattttat accaaaaaca
    11161 attagaagaa gaaatcaatg aggcaagaat tgccgaaggc aaacgtcctt ttggttcaat
    11221 cattcgtcag gaggtggtcg aaagaaaatt tagcatcgca gatccagaaa gtggttatta
    11281 tgtaaaaaca gaacgagaaa aacagtttgc ttattctgct cataccgttg gtgatgaaaa
    11341 tggttttgta ttagatgtca tgattacgcc tggaaatcta catgatagcc gaatgctcgt
    11401 gccacaaatc gaacgcgtta aatcacgtta tggtgtagct gctaatgctg cgtacaaaac
    11461 accttggaac gtcaagtatt taatcgaacg aaaactacga cccattctcc cttatatcag
    11521 tttcgcacaa ctactcgaga tggctataaa aaatatgtat ctaaatcttt tatttgtgaa
    11581 agttgtccat tattgaaaaa ttgtacagaa agccaaaaac accaaaaaga aatacatcga
    11641 catatttggg aagactactt agatgaagca gaacatttac gccatacggt gtacaatcgt
    11701 gaaaaatata aaaaaagaaa agaaacgatt gaacgcattt ttgcagacgc aaaggaaaaa
    11761 catggaatgc gctacaccaa gtatcgaggc ttggaaaaaa tcaggtgcat acaatgcttg
    11821 tttttgtcgc aatgaatctg aaaaaattag ctacttggca gtgggagcat atgtcgttat
    11881 atcttttatt atacaaaaat agacaaaagt atcagtctac actcttagta aagaggaaac
    11941 tgatgctttt gtctacagtc ttagagagtg ggacaatagt tttttcttct ttacgtcttt
    12001 tcctctccat gtattttcct aattttctta atttaacgcc atgagtgcca agccaatgtc
    12061 aatcttggct ccttgtttcc ttcataagtg gaaatccgtt tccgatagat cgaaccttct
    12121 ttttcctcta aaagtttttt tacattctgc tttgaaataa cgccatgtat tattcactaa
    12181 aatttgtcgg tttcgctcac tttttgcttt cgtacattga ctacgaacag gtcagcaccg
    12241 accactttca cattcgtaaa ttttgaagac acgtataaat ccacttttat cttttcttcg
    12301 actaaagcgt tgaccgcaaa agcgacatct gtttcagaaa tatattgttc catatctaat
    12361 ggtaaaattt tttggttgat ggtataattt ttaaacataa agcactcgct tcctttctga
    12421 ttgggtttgg tcactttaat cctacaggga tgagtgcttt ttgtgtacct taaaatcagt
    12481 aaatatccat ccgtgaaaac gggtggcttt ttaacagccc tagaagggct caccactcac
    12541 agccctatct ctctttaact atttaaatgg atctacatac tcttgtttac ttatactgtc
    12601 tctaattcga tcatctgctt cttgttctca aatatatatt tcaattgttt tttgatttaa
    12661 cccaaccgta ctcacgtagt atcctttggt ccaaaagctt ttattcccat acttatattt
    12721 caaatttgca tgtttttcat ggattaaggt tgcacttcgt ccttttaagt agcccataaa
    12781 actagaaata ctaatctttg gcggtattct tactaacata tgaatgtgat caggcattgc
    12841 atgagcttca atgatttcaa catctttcct ctcacacaat tttcttaata tctggccaat
    12901 acttactctt aactttccat aaatcacttt tcgtcgatac ttcggggtaa agactatgtg
    12961 atacttacaa tcccatctcg tatgtgctaa acttttatcg ctaaagctat ttcgtccacg
    13021 cgtagaaacg cgcgtttttt tgtttcgtac gctacgccaa cgaaactgac taaagtcaat
    13081 aaaaaaagtg gggcaataat cagatttttt tctgactatt gtcccactct ctttttatta
    13141 ctcttcatct tctactattc cactaattaa ttagttgaca gatacaatgc tttcacatcc
    13201 tgcacgaaca aactcgggct ctgaaccaat cacttgcgag ttgataaatt caatgaccat
    13261 aggaagatta atccgacata aagtttaatc tgttgtcctt ccattatcag tttagaaatg
    13321 atattagtag gtgtaccgcc taaaagatcg catagtacca caaaatcatt taacgaatct
    13381 atgacagtaa gagcttttgt ctgtatgttt cagtgccatc ttctggtaat aaaggtaacg
    13441 tgtagatatt ctcttgaggt cccataatca tttttgtact ttttttcaat tcctcacaaa
    13501 attttccgtg actaatcaat atcaattttc tactcatttt tggctctccc ttatttcgaa
    13561 atcacacaca atgcagataa agccacacac aagtaatacg ataaaaatcg ctcgagttgg
    13621 gtcatatttt tctttcctaa caaccaataa acacctcgac gatcccagcg agtaagattt
    13681 tagataatat catatcgata tagttttgca tattcaatgt cacatcgcca atcgttggta
    13741 ccataaaaat ttaatatcaa tcattgttgc aactaatgct cctaccatga acactcttaa
    13801 taaagtcgct acgtccgtta atacagttaa gcgagattac actagatgat ctgttcctgc
    13861 caaggcaaga gccagaagcg gttgcctgcc catttgcctt tggtgtgtcg gagctgtccg
    13921 ataaagttca ccgcccgatc cgctctggct ttgtcgtagt gacattccga aagcatgaat
    13981 cggcttggtg tgtattcctt taatttggga tagccctttg gtctggtttc tgccatcagc
    14041 taccacctcc caacagagcc tccatcgcat cttctgctcc gacaccaccg ccatcaccgg
    14101 caatgatacg gcttctggac gaaggcgtca gaccgaactg ctcggaaaat cggttcataa
    14161 ttttcagata ggtctgggca ataaacacct gtggtacctg ctgccaatag ccggataggg
    14221 ttttcacgat gataccgtgc tgggtaatga attcctcggc ttccttccag cgggcgtagg
    14281 cttggcacta accggcaaag gcagccatat ccacatctgt caagattccg atggcctcca
    14341 tctgctttgc cagacgcttc cattccttct ttgcctctgg ttccagccac ttcggacagg
    14401 tcggtgcctt cttttccggc gttgactctt ttgcattgag tgggcgattg cccggatttc
    14461 cctccagctt cttcatggct gtcggggttg attttcttcc tctggttgcc acagtcgtca
    14521 cctcccttca atgtatttct gccagtagac agagaacaga gccaagtcga aacctgactc
    14581 tcttctctat ctgctaactt gtatttcagt ccactcttct gatgaatcgc acccgcagga
    14641 ttttcaagat gccgcaggca aattccaaga agtttctgac cgcatcataa ccatcgtagc
    14701 cgtgtagcca catccttcca cctcgccgcc gtcctcgtcg ctgatataaa tgattctgta
    14761 ttcgctcatc tgttgttttc tccagtcttt tgtttttttg tagtacatat atcactctaa
    14821 aagtgattat tatcaagtcg tttgaaagcc ataatgtaca caatcattcg actggttttt
    14881 ggttcataat tgaccgccaa agtgagcaaa agaaagggac ctctgtctgt ttcagaagtc
    14941 cctttcggta tttggttctt agtggttcag gctgtattct caaacctcat actcatcttc
    15001 gaggtctgcc tctgcaatga tctggccgat gctgtcgtaa cgctggacct gcatctggat
    15061 ggcatccttg tctgctccct cgtccatcat cttcagcagc ttgtctgatt cctttttgta
    15121 ggcccagaaa aggatctcct gaaggctggt ctcctgcttt ttcttgcgaa gggcgacctt
    15181 cttctcttcc accgcctcgt tcaacttggt gaactctgcc caagcaagga taccgtctcg
    15241 cttgattgcg atctccacat ccttcagctc cgggatggtc tttgcaccct tgatctcctt
    15301 caaatatttc tttgcctttt cgctcattgc cattagcgtt tcctccttgt ttttgggatt
    15361 ttcccctttg gttgtgtgta tattgccata gtctctcgac tatatcaagt caatccacag
    15421 gcatatacta cacaatcatt tggagctgta tttgtataca ttatgccgat ttatgagaga
    15481 agaaaaggct ccagccgttc gactggaacc ttgggggggt cggtttctta ggcggcgtgg
    15541 cggtgtagac cttgaggtag ctgatgttct tccagacgtc cgtgcccttc agtctgacca
    15601 tgccgtccag ctctcggtcg agggtgaact tgcggaaaag cttgatgcgg ttgaggctgt
    15661 ttgctagctc cttgccgttc ttggcatcca gaactgcgtc ctcgatctcc gcaatactaa
    15721 tttcctgtct aaaccaaagg ttgctcaagg cttcgggaat gccgtttgcg gtctgcaggg
    15781 ggttgaaagt ttccaataca gcaggggtcg aaaccacctg tccgagctgg aattttgcgt
    15841 tccctaaaat catctgcata atttcttcca tgtgaatcat ccatttctgc cgttgtggta
    15901 ttccctttgg cagtacagta ctatatatca ctctgaatcg tacatttatc aagaagcgga
    15961 tttttgtgga atcaccaatt cgatataata gtaattgcat gaaaaatcta agcactggat
    16021 tggtaggtga tgattatacg tgacgatcac atttacacct gtgattcctg ccactacagc
    16081 ttccctgccg acgaacagcc agagcgttgt cctgactgcg aaaagacagc aactcggctg
    16141 gataccgaaa tcgaaactga agattactat cgtgttcgtg ctgaaatcaa agctgagatt
    16201 aaagctttga atgcgggtta acgacaggta ctgaccggcg gctcaacacc gccggctttt
    16261 tattaccaca tcttgcggaa ttcgctggga cgaacacctt ccaccttgaa aaaagttctg
    16321 gaaaaatagt ttgcatctgt tatgccaatt tttgttgcaa tctcttccat acttagattt
    16381 gtaaagcgta gcaagtgctt ggcctgtgtg attcgtttct gattcagata accgacaaca
    16441 gttgtaccgt aagtttcacg aaaaatctta gctaagtact gtttattgat aaaaaactct
    16501 gcactcaact gatccagcgt aatcttctcc gtgtaatggt catccagata ttgttttatg
    16561 ttctgcaatt ccattttttt tgtagagaaa ttcggcactt tgtcaggatt ccaagaatct
    16621 tccatcaaat gcatcagcaa ttcactgagt agaacattga ttttcatatc ccggacatac
    16681 tcctgtccct ctgccaccat atgaaggctc ctcagcaagt cagcatactt atctgttttt
    16741 gatgttttaa agaccggttg accacctcgt tcaaggtatt ttttgtagac ttccgtcata
    16801 ccaatgccat taaaatggca ccaccgcaaa gtccacaaat catcttctga tgactcatgg
    16861 acatacggct tcaaacagtc aataaacacc atatctccta cttgaagcgt atatttctgc
    16921 cccttatact ccaatgtgcc tgaaccaact tctaccagga aacaaaggta agatgacaat
    16981 cctgtacgcc tagatgtatg tgccttcaga gcagtcagct gtccaatttc ctgcaaatac
    17041 aaaagagagg atcttgcaaa gaacgatgcc gtgtacagca cacgatttga cttcaccgat
    17101 ttcaaagcgt tagaaaacag ttcctccatt acaagatttc tcctttcttt tcttactcga
    17161 acatttccgc cagttcagca gccataatag cttccatagc ttcggcggct tccttgttct
    17221 ctgcgctgac gctgatatag gtcttcagct tcggctcagt accagaagga cgaaccacaa
    17281 cagagcagtt atcttccagc ataaacttca aaacatcaga cttcggcaga ccattcaggc
    17341 ccttactgta gtctaaagtt tcaataacct tcttaccacc aattatatcg agacccttgt
    17401 ggaattcaac cataatttcc tgcatcttgg taaaacctgc cgcaccgtca aactcgaagg
    17461 aatgcagggt gttcaaacaa tagccatact ttgtataaat ctcgttcagc ttatccagca
    17521 ggctgatacc ctgagtcttg tagtaagaga acatttcaca gattagataa gcagcgttaa
    17581 caccgtcctt gtcacggaca tagctaccgg acagatagcc gtaagattcc tcaaagccga
    17641 agatatagct gtcaacctta ccagcctttt ccaacatacc aatctgctca ccgataaact
    17701 taaagccggt cagcacatcg atggtacgaa caccatagtt ggatgcgata cgttcaccca
    17761 aatccatggt gacgatggtc ttgaccatca cagggtcagc aggcattttt ccatgcttaa
    17821 ttctctgaga acagatgtag tccagaagta gcagaccagt ctcattacca gacaacagaa
    17881 catagtcacc atgtgcgctc ttaactgcga taccaacacg gtcgcagtca gggtcagtgg
    17941 ccaacagcag atccgcattg tacttcttgg catactccat acccagagac atagcttcct
    18001 taatttcagg gttcggataa ggacaagttg ggaaattacc gtccggcaga cgctgttctt
    18061 ccacaacggt cacattgctg tatcccatct ctgccagggt gcgggtaaca ggcaccagac
    18121 cggtaccatt cagaggagaa tacacgatag caacattctt gtccacttct tcgccaaaca
    18181 ggacggactg ccccttcact tcttcgatga aagcagtcag aacttccgac tgaatggatg
    18241 caatcttaga agcatcgcca tccatcttta catcagcaaa gatgtccagc ttttcgattt
    18301 ctgccagaat tgcagtagca gcctcggtag taatctgaca gccgtctgca ccgtatacct
    18361 tgtagccgtt atatttagaa gggttatgag atgccgtaat cataacaccg gcatctgcct
    18421 tcagataacg agtcgcaaaa gatactgtag gaacaggaag cagttctggc cacaagtgca
    18481 cctgaatacc atttgcagca aagatgtctg cggcagtctt tgcaaacaca tcagatttga
    18541 tacgggaatc atagccaacc accacggaag cggcttcata gttcttattc agatagtctg
    18601 ccagaccttg gcttgcctta cctacggtgt gtacgttcat gcgattagtg cctgcaccga
    18661 tggtaccacg cagaccacca gtaccgaaag acaaattttt atagaaagag tcctcaatgt
    18721 ccttctcaga ataggaacgc agttcttcta taatatctgc attggcatga ttcagccaac
    18781 gctcatattc tactttataa ttcatattat tatcctctca catccagaaa ctgaatcgac
    18841 ccgtgaatgc tgatttcagt agaatcggcc ggcacaaaaa ggcagtcccc cttatagatg
    18901 tccaacgatt cattatcaaa tcgaacggta ccacagccat tgacacacag caacacacgg
    18961 aagctgattg aatccgcacg atagtgtacc gtctgtcttc tctcagtgtt gacaatcata
    19021 cgagagacct cgaaatgctt gcatctgcaa agcaattccg cagctacacc agcacgatat
    19081 tttagaacac gaagcggctg tttcggttct gacaaccctt tcaagttcgc tacttccagc
    19141 gctttgtcta catgaagttc tctcttttta ccatttttgt caacacggtc ataatcgtag
    19201 agacgataag tcagattgga attttcctga atttctgcaa ttagtgcacc cgcaccaatc
    19261 gcatgaatcg ttcccgcctc aataaagaac acatcattct ttttgaccgg aaccttctga
    19321 agataacgct caacagttcc ctgagcaatc gcttcacgga tcacagcttc ttctgttatt
    19381 ttctgcagcc catagattaa gctggcatcc agtacatacc acatctctgt ctttccaagc
    19441 tgcccgtttt ctttttcaat tgcatattca tctgtgggat gtacctgaac agacaaatcc
    19501 tttttcgcat caatgaattt gatcaggatc ggcaattctc ctttggtctg cggatgcgtt
    19561 cccagaaact ctgggtgttc ttgcaacacc tccgtcaagg tcatcccctg atactctgac
    19621 cagacacaac aaagctcggt ccatccgggt gcgtagagca ttccaagttt ccgcaagagg
    19681 agacatctca attccttttg caaattcatc attcaggcgg ttccccccca cagataatcc
    19741 tttgcggaag gcttcaataa aaacggtttc tgtataacga gccctcctcc gttttttaat
    19801 actctaactc aaatttctgt ttatctttaa cattgatatc cttgccaagc tgtacttcaa
    19861 tcagcttcag ctcagtatct gccataatgg tatgccgaca gccagcactc atggtgatca
    19921 catcgccagc cttaacaacc tgctcatatc catccacgat ggtcttacca gtaccggcca
    19981 gaaccaccca cacctcgtca cggttcttgt ggctgtgata attcatggag tgactagcat
    20041 tcagagtaac cttaatggtc atgctctctg cttctacatc cataacctta taactacccc
    20101 aagacttctc tgcgaacatg atctgctgct cgaacttgtc aacgaaaggc ttaatatagc
    20161 tggactgttc cttatcggaa accagaatac cttcccgaga tgcacagatg accacatcat
    20221 gcagacccat agccaacaca ggaacatcca gttcgttcag gatgtgtacg ccatcgcaat
    20281 tctcattcat aacaccttta ccgataatgg attcctccat accttcggtc agagtattcc
    20341 aagtccccag atccttccac ataccagcaa aacgctgtac ctgaatcttg tcctcatgct
    20401 caacaacggc atagtcgaag gaaatcttag tcagagtatc gtatttgttg aacagatcct
    20461 gataatctac aaagtcaatc agctgatgtg cacgctccat gacatacttc agcttgtaga
    20521 caaacacacc accgttccac agtgcaccct gtgcgatata ttcctttgcc acagcctcag
    20581 aaggtttttc cttgaaggta tttacgaaag cagtctgctc tgcgctctca ggaatgatgt
    20641 agccgtactt ctcggaagga taagtcggtt caatacccat gagcaccaga ttagcttcgc
    20701 ctttgtcagc ctgatcggac agagatttca gggcctcaaa atagtcatct tctacgtaag
    20761 ggtcaaccgg gcaaacaact acggactctt ctggatcaat gcccatcaca tctaccagat
    20821 aagcggtagc caatgcgatt gccgggaagg tatcgcggcg acaaggctct acagatacac
    20881 ccacatcctc accaagttgg ttatggatag cagaaacctg tgtcttagag gttgcaatcg
    20941 taacagttgc gtcgttatct accttcttaa tctggcggta gacacgctga accatggatt
    21001 catatccatc ttcagttttg aaaatcttaa tgaactgctt ggaacggatg tcattagaca
    21061 gcggccaaag gcgcttacca gaaccgccag acagtaaaac aatattcata atgatctctc
    21121 ctttttataa gaaagaggct gctgcaatcc tcaaaaatca cagcaacctc ggtaaattag
    21181 cgttcagcac gcatcgggtt attcaggaag tcctcgtagg acagacggat gccatcttcc
    21241 aactcagtct tatatgtcca tcccagcttg gttgccttgg aaacatccag cagcttacga
    21301 ggtgtaccgt tcggcttgct ggtatcccac agaatctcgc cttcgtaacc aataaccttt
    21361 gctaccatct cggtcagttc cttgatagac agttccttgc cagtacctgc attaacagtc
    21421 tcgtcaccgc tatagttatt catcaggaac acacacaggt ttgccagatc gtcaacatat
    21481 aggaattcgc gcagaggaga accatcaccc cagcaggtaa cagtaggcag acctgcttcc
    21541 ttagcctcat ggaagcgacg aatcaaagcg gggagcacat gactgtgagt aggatgatag
    21601 ttgtcgttag gtccatacag gttagtaggc ataacagaga tatagtcagt accgtactgc
    21661 ttgtttagaa actcacagta cttcaggcca gaaatctttg ccagtgcata agcctcgttg
    21721 gtcttttcca gctcacttgt cagcagacag ctttccggca tcggctgcgg tgccatacgc
    21781 ggatagatac aggaagaacc gaggaactgt aacttcttac agccattctc ccatgcggag
    21841 ttgatgacgt tcatttccag aatcatgttt tcatacatga agtctgccag agcgttctgg
    21901 tttgcgataa taccgccaac ctttgcagca gcgagaaata cataatccgg cttttcctgt
    21961 gcgaaaaatg cttcaacagc gtcctgacgg cacaggtcaa gctccttatg ggtgcgggtg
    22021 ataatattgt tgtagtcctg acggttcagc tcgcgcacga ttgcggaacc agccatgcca
    22081 cgatgaccgg ctacgtagat ttttgcgtct ttttccatca taataatgct tgctcctttc
    22141 taaatttaga gcatctctca ttgcatgaga gaaatcaatt tgtctgcgat ttcgctcgca
    22201 gcatcataaa atgtatcaaa atttgaggtg tctagctgtt tgaggtcctc aatcacccgc
    22261 tctacgcggt ggaggttttc cggtgtgacg gaaattgcca gacccagttt ttgcaattta
    22321 caaatagttg ttctatcttc caaaactgta tcgcgggcga acagtgccat cggacgctgt
    22381 gcgagaatac actccgcaac agttccccat ccagcctttg taataacgta atctgccgcc
    22441 gctatatagt cctgtgtatt gggggtgctg ttagaaataa cggttacgtt ttctcccaca
    22501 agcggaacac ctagcgttgt aatgaaatca tacggcgcgt gactgacatc aatcggctgt
    22561 ttgaaccgcg cggacatacc gagtgcgaca aatacaggcg gtttttcatg ctgtgattta
    22621 atgcgttgca cttcgtcgtt atgaatcgga cgcgccacaa cggaagtcgg tgttttttcg
    22681 ctgttttgga gaaattccaa catttcttcg ttatttagcg cataaagcat ggtgtgctga
    22741 attttaccgt aacgcttggc atattctttc caaatatgtt cgggtaaaaa ttcgcgatac
    22801 agctctgtcc aagtgaagtt tcctacatac aggaaaggta ctcctgccat atcgcaggca
    22861 tccattgccc agattggcat atcgcaaagc actgcgctga cagcttctcg cttgagccat
    22921 tcggcttctg tctttgccaa agaaggaacc tttgccaaaa aatattcaca gatctcggtc
    22981 agcttacccg tgtccaccag tagggtgccc tcacggttaa tcagaccgat atctgtgttt
    23041 attggacgat agcgcacgcg gtctatcagc tctttgggca gttcctgctc caaattgcgc
    23101 tttgcaaaat ccagatgatt tgcgccgcaa accagtgtaa tcttcgcttc gcatcggcag
    23161 agtgttgcca taataatggg cagattccgc gcgatatgtc cgaagccgtg actggaaaga
    23221 tagaaacaga tatgtttatt caatgtcagc ttacttgact gcgttcttca ttgcagcttc
    23281 gcgctttgcc aattcacggt catgctttgc catgatgtta accagttcct cgtaagaggt
    23341 cttctgcgga ttccaaccga gaacggtctt tgccttagtc gggtcgcccc acaggttgtc
    23401 aacgtcagtc ggacggaacc actgtggatt tacacaaacg agcatcttgc cggtttcaac
    23461 atcgtagccc ttttcatcaa tgccagtgcc ttcccaacga atggtcatgc catttgctgc
    23521 gaatgccttc tcggtgaagt cacgaacagt gtgctgctcg ccggtagcga tcacgaagtc
    23581 ctcgggagtc tcatgctgga gaatcatcca catgcactca acatagtcct ttgcatagcc
    23641 ccagtcacgc agggagtcca tgttgcccag ttccagatgg tcctgcaggc cttctgcaat
    23701 gcggccggca gcgagggtga tcttacgggt gacgaaattc tcaccgcgac gttcggattc
    23761 atggttgaac agaataccgt tgacagcgaa catgccataa gcttcacgat attccttagt
    23821 gatccagaag ccatactgct ttgcaacagc ataagggctg taaggatgaa acggagtggt
    23881 ttcacgctga ggaacttctt caaccttgcc atacagctca gaagtagatg cctgataaat
    23941 cttagtcttc ttcgtcaggc ccagaatacg gcaagcttcc agaatacgca taacgcccaa
    24001 agcatcaaca tcgccggagt actcaggaac atcaaaagaa acctgaacat ggctctgtgc
    24061 agcgaggtta tagatttcat caggctgaac aatgctgatg atacgaatca gagaagatga
    24121 gtcggacagg tcaccgtcat gaagggtgat cttgcccatc aaatggtcaa tgcgagcggt
    24181 attggaaata gaagcacggc gagtgatacc gtgaacttcg tagcccttct ctagcaggaa
    24241 atctgccaga taggaaccgt cctgaccagt aataccagta atcagcgctt ttttcatgat
    24301 acattatcct ttcctatgta agtgataagg ccatataaat ggctcgtaat ttctaatact
    24361 tttcaagaat acacgataat tttcgatatt tcatagaaca atctacgcac gcattagcac
    24421 aatattagtt tttcgtgaat tggaatggca acagtttttt tgacaaattt tataaggtgc
    24481 agaacttctt tccgtatgct attccgattg tccttgacaa tgagcctcct cggatgtgac
    24541 gatcttcggc aggagctaac agttaaagtt agactgcctc gctagcgtta gcacatccga
    24601 gctcattatc aaggattcgc tgcgccaatc tctggttacg gtaaccaacc ggtgtctcgt
    24661 agccaagtgt accgtgcaac cgaaggcggt tccaccaatt gacatagtca aataactcca
    24721 aatccaattg ttgtaaggtt tcaaatgtgt attgatagac aaattctact ttcaacgact
    24781 tataagttga ttcagctacg gcattatcaa aaggacagcc tttatgactc aatgatcgat
    24841 tgatgtcaaa agttgttgat aattcatcaa tagcttggtt atcaaactct tttccacgat
    24901 cagtatgaaa aatctcaacc tctgtcagag gttgtcagac tgtagacaaa agctgttcca
    24961 aactcgtaac tcgagcttgg aacagctttt tatctacttc gtttcgaatt tttgaacaaa
    25021 aaaataaagg ctccttgcct ttccatagcc aggtggctaa tttctttaaa ttcattgcag
    25081 caaacactag catcgtatgc gtcgcgactt tttccaagcc tcgatacttg gtccaacgca
    25141 tcccatgctt ttcttttgca tccgcaaata ttcgttcaat cgtttgtttc cgttttttgt
    25201 aaattgattt attcagatct gttaggcgaa gatgttccac ttcatccatc agatctcccc
    25261 aaacatgtct cgtgatgact cgttgatgat ttttacttat ggtacattgg tttagcagag
    25321 gacagttcac acattctttt ggattggatt tgtattctcg gtacccttct cgagtaaccg
    25381 ttgaaaaagc gagcatttga tcttgcggac aaatataaca atcaaaatac tcgtcataga
    25441 gaaactcatt ttttgataat agctcctttt tccctttggg ccttgaataa ggcaaacaag
    25501 gtcgaaggtt caaatgagtc aaaaagtgaa caaacttagg tgtcttatac ccagcatcag
    25561 cgacaacaca attgatttca ggaaaaagtc tcttcgattg tttgacgagc tgaaaggcga
    25621 cttgactgtc atgaatattt ctaggagtga tgattgtgct aagaataaat ccattgtcgt
    25681 cgcatgaagt atggacagaa taagcaaatt gtttttctcg ttcgcctttg acgtagtagc
    25741 cgctttccgg atcagcttta cttatttttc tttctttcag cttcacttcc ttttctaagt
    25801 ccaaagtaaa agggcgtttt ccagcctcta ttcgttgacg attgatctca tcttctaatt
    25861 catcctgata ggctttcgct tcatcatggg tcatttcttt cgtaaactta tgtttattgg
    25921 cgttagcttt gatgtgggta gaatccagat acaaattatc ctctgttaca aaacctgctt
    25981 taactgcttg ttctaaaata taggcaaaaa tatcctcaaa caccgtcgtt tctctaaatc
    26041 ggcgaacata attctttcca aaagttgaga aaggggggat tttctcctcg aaggagtagc
    26101 ctaaaaacca gcggtaagcg acattggtat cgacttcctt aatggtttgt cgcatggaac
    26161 ggataccgaa taaatactga ataaacacca atttgatcag aatcactgga tcgatacttg
    26221 ggcgacctaa atcggagtaa gtggcttcga cgattggata aataaattca aaatcaagcg
    26281 cggcatcaat ctttcgaacg agatgatctt gaggaactag atcatcaatc gtaagcatcg
    26341 caaattgatt tctaccattc gtattgtttt tagacatcat agctatcact ccttgcattc
    26401 gttttcataa atctattata aaagaaaaga ctgtagacat catccataaa atggactttg
    26461 tctacagtct ggataacgtg attttttgct gtaatgacaa ggttttagct gtttcagata
    26521 ccatgtatcc aaaaatagtt tattgagaaa ataggagagt atttgatact aactagtagg
    26581 aaaaaatgag ataaaaagta aatggaatca tttaaggtaa tctgaaataa aaaatataca
    26641 gccctgtggt actttaccta caaggctgta tatatttttt actctcagcg tttttgactc
    26701 cgtgtctgac tccgttttat tgattttgaa tgttattcaa tgaccattta acaggtcaaa
    26761 tttgatgttt ttgattccgt atgacgccgt ttgatatcta gtgatatagt gatttgagtc
    26821 tacatcgaat aagggaataa accaataaaa aatgatttag aatattaaaa taacaaaaaa
    26881 gaggactacc tgtattagtc ctcttttttg accagatttt gaccagtcta ttttacatcc
    26941 tagtatattt atatgagcta attttatgat taaatggtaa gtttttcctt gtgtgtttta
    27001 gtttaaacta gtgtgtaatt caaaaatcta tatggaagga acagtattaa gaatagaaca
    27061 gggttctcta catgatggtg ctggtttacg gaccgttgtt tatttaaagg gctgcccatt
    27121 acgctgtgcc tggtgttcga ttcccgaatc acaaagcaag cagattgaaa aaggatttgg
    27181 ccagaccatg accgctgaag aggtaatgga tgagattgag aaggatgctg ttttttactt
    27241 tcactcggat ggcggagtga ccattagcgg aggcgaggca ctggttcagg cggattttgc
    27301 taaagaaatt ttgcaaaaat cgaaatacat tggaatcaat accgtactgg aaaccagctt
    27361 ttgtggtgct tataatgaaa tccaaaaggt agctccctat gtggatacat tgtttgtgga
    27421 tgtaaaaatg tttaccagca agctccacaa acaatggacc ggcttagata accaacaaat
    27481 tttgaagaat attcgtcgct ttttaattga gtatcctaac tgcgaagtgc gaattcgagt
    27541 tcctgtggtt ccaggtatca atatgaacct gaccgagctg ctgacgattg cttgttttgt
    27601 ggcagatctt gatcggttcg taccgttaga attactaccg taccactgct atggtatgca
    27661 cggttaccaa gcattgggac tggagtatcc gttggcagac acgccagcgc cttcacctaa
    27721 agaaatgttt gcattggcag atcaactggc tcgcacggtt cctcatttgc tggtcacagc
    27781 tttaaccaaa acatttattt atttattgaa tccaagcttt atcttatgga taaatgaaag
    27841 acactcacta gctgcagcca gctcaagaat agagcttttg ctgaagtcag tgagtgtctt
    27901 tttacgatgt tttttcgaag ttaatttgtc gaatgaacac tggctcaatc ggtacatctt
    27961 cactgtttgt cggctgagct gcgatcgctg ctacgatttc taacccttgg tatacctgtc
    28021 caaaaacagt ataacgacca tccagctccg gtagtcctcc aagctccaag tatgcttgct
    28081 ttacattagc aggtcagcct gcgcctttgt gttttgcaca ataaaaaact ggttgccgtt
    28141 ggtgtggggg ccgtggtccc ctaaggccaa ggcgccatta aaatgataaa gtccgcgatg
    28201 cacttcatca gcgaaaaagc cctcatagct ggaaacagct tcatcaccag aaccatccaa
    28261 agcgccacct tgaataacaa attccttaat gacacgagcc gaaaggtgtg ttgtcataaa
    28321 cgccttgctc agctagggag cgccagttgg ctacagccag gggagcttgg tcaggaaata
    28381 agcggagacg aatttcacca gcatcggtga ccagcacaca aacttcttcc tgctgcggtt
    28441 tttctaattg aaagagagga aggtttgcaa ctgaaacgcc ttgatcctgc catcaaatat
    28501 cgaaaatccg ccactcgacc ttcgcctgat caccaaggcg agccattccc aataaaacgg
    28561 tataggcggt ttcatccgct tgaaaggtca attgcagctg tcctcgtaaa tcgttgtagt
    28621 catctggggc ggctacttga taaaaaagat gaaactgcgc atgcaaatat tccaaaggct
    28681 gatctttaaa ggctgcaaaa taagcctgaa ctttttcccg ctgcaagctg tcagccacca
    28741 aaaaattttc cagttgttgt tttggaacgg ctgctaacaa ggatcggcaa accgcctcaa
    28801 ttttcaacgc atcccaatgt cgcgcaatta aataatggat gggtgcctct tgattgtagt
    28861 cccacaggtt gctcattttt ttcaccactt tcttctatta tataggaatc acaaaatcgg
    28921 cagcggcgtc aggcggcgtt cttttccttg aatgactagc aacttttcta cctgacagtc
    28981 tgccaacagc tgactcattt ttttaaagcc cagctgataa tcttcggcaa catgagcatc
    29041 cgagcctaag gtaaagagct ttccgccgac actttgatac aaaggaacgg cataacggta
    29101 aaggtcttcg ttgccgtatt tcaagaagct cttggcattt aactccatcg ccaattctcg
    29161 ttcaacaacc tttttgaaaa tcgttagcag ctgagcctca aaatgctccg cgaattcttc
    29221 cgctgtgaag gtgaagcggc gtaatccata atcaaagtga gtcaaaatat ctccttctgg
    29281 aaaatccgtc aagacctgca acatctgatc aaaatattcc ttggtagttt gaatgggatc
    29341 tttggttaaa accacatcgt ccatataatc aaagcggcca ttttgatgaa tacttaccag
    29401 ctttaaatca taaggatgct gagcgaggta atccacgatc cgctcttctt gtcctggaac
    29461 aacgccaatc tcgatacctc gcagaaattt ggtggaatag gtttctttta aagagtccag
    29521 tttgtttata taggctggat aatccggaat gtcatctttt ccggtagatg gattgtttaa
    29581 atcaaagtga tccgtagaaa cgaaaaactc cggctgatag gctaaatagt tttcaaattt
    29641 ttcctctgaa tcaaaggaaa aatacgtgtg gagatgctga tcataatact gcatagggag
    29701 cctccttttt tctactatca taccgcaaaa gctttagaag gttaacggga attcgtcgaa
    29761 atttacaaac catatacaac ctttacattg ttcatgaaac cttttcaaga aactgattct
    29821 ctcattacaa agctttgtta gaatggaatt atcgaaaggg gagaagaatg aatgaaaatg
    29881 aatgaaaaaa ttcgtaacat gactatcggt ttattttgtg cagcaacagt aagtatcctg
    29941 ctgacaggct gcggctcagg tgaagcaacg aagcaatcgg ctgcggcaga cgactcttta
    30001 gatacgatta tagaaaaagc caaggaagaa ggagagattg ccagcttggg aatgccggat
    30061 acttgggcaa attgggtagg cacttggaac gaccttgaaa aagaatacgg cttaagtcac
    30121 gtggatacgg atatgtccag tgcagaagaa ttggctaagt ttgaatcaga aggaaaaaat
    30181 ggaaccgccg atattggtga tgtcggtatc agcttcggtc cgttggctga aagcaaagag
    30241 ttaaccttac cttataagac caactattgg gaggaaattc cggattgggc aaaggatgat
    30301 gatggggatt ggttgttaag ctatacggga accatttcct ttatcaccga taaagagaat
    30361 gtgaagcaag caccgactag ctggaaggag ctgcaagagg gtgactatca agttagcgtg
    30421 ggggatgtga cgattgccaa ccaagcacaa tttgctgtat tggctgcggc gattgccaac
    30481 ggaggtgacg aaaaggatat tcagccaggt ctgaattact acaaaaaaat ggcagaaaaa
    30541 ggccgtttgt ccaccgttga tgccagcgta gcaaatcttg aaaaaggtga aatcgatgtg
    30601 gcagttgttt gggacttcaa tggactaaat tatcgtgacc aaattgactc cgagcgtttt
    30661 gaggtaactg tgccaacaga cggctccatc attagcgggt atacaacctt aatcaataaa
    30721 aatgcccctc atcccaatgc ggcaaagcta gcacgggaat atattttatc tgatgaaggg
    30781 caaatcaatt tggcaaaggg ctatgcgcga cctattcgca aggtagagct gcctaaagaa
    30841 gtagctgaaa aattactgcc ggaggatgct tatgaagcgg cggtgccagt tgaagacaat
    30901 gaagcttgga acaagacctc tgtagagctt ccagagcttt ggcaggcgga ggtactgacc
    30961 tatgcaaagt agacttgaca aactgattgt agttatacta gacggctgtc gctacgacac
    31021 agccgtcgcc cagcttgggt tcatgaatca tttagttgag caccagcaag caagcttatt
    31081 gaaggtaaaa agtgagctgc ccagcaattc acgtccgtta tacgaagtac tgatgaccgg
    31141 cgttccagcc tatgaaaatg gcatctatag taattaccat gctcagcgat ccaaagagtg
    31201 gtcgctgttt gaattagtta aggaagctgg cggaaaaaca ggagccgccg cttaccactg
    31261 gtacagcgag ttgtacaatc aagcccccta taatcgtttg gttgatcgca tccagcatca
    31321 ggaggagcga ctgattcagc atggcatctt ttatagtgag gacacttacc ctgattcgca
    31381 tttatttgcg gatgcccatt atttagtgaa tcagtatcag ccagactttt tggtcgtaca
    31441 ttcgatgaat attgatgatg tcggtcacaa atttaccgcc gattctcatg aatatgcagc
    31501 agcggttaat caggcggaca gattattggc tatttacctt cctgaatggc tgcaaaaagg
    31561 ttatcaagtc gtggtgactg cggatcacgg gatggatgcg cacggactgc atggcggcag
    31621 cttggctgca catcgtgaag ttccttttta tttgatttca aataaacgcc aaaagctgaa
    31681 ggaacaaact gtaccacagc tgctggcggc tccattgttt tgctggttat taggaattgc
    31741 accgtcagag aaaatgcagg acattcaaga attgatgagg ggatgaaaga gatgaaaaaa
    31801 cgcttggttc tggttcctgc ctcctttatc ttctgtgcat ttttactgct gccgctgctt
    31861 tttatggttc tgtgcagctt gcacagtgat ttaactaacc agtggacatt ggccaattac
    31921 agtgatattt tcagcaacaa atattacaca caggcctttg ttaacagcgt actgattgct
    31981 gtcagctcca gtgtgattgg gttaatcggg acgtttattt tatgtttatg cttaatgaat
    32041 ctatcgacta aattgcagga gaaaatcacc tttgtttcca atttggcagc taattttgct
    32101 gggattccgc tggcattctc ttttattatt ttgttgggga atgtaggtgt gctgaaaatg
    32161 attttgccat ttctagcgga cttcaatttg tattcttggt ggggattgac catcacgtat
    32221 acctatttcc aaattccgtt aggggtcttg tttttgtatc ccagcatgaa ggaagtgaaa
    32281 aaggaatggc tggagtccgc acaattgctg ggcgcttcat cagcgtatgc ttggttcaag
    32341 gtggctttgc cttttttgcg accatcgatt gccagcacct ttgtcatctt atttgctaat
    32401 ggcatgggga cctatgaaac agcgtatgcc ctgaccagca gtaatgtaaa tcttttaacg
    32461 attcgaattg cggctttagt gtcgggagat gtgttcgcca agcctaattt aggcagtgcg
    32521 ttggcagtcg ctttaggtgt cctgctggta acggcaatgt tgattattca aaagaaaggc
    32581 aaggtggtgc agacgtgaaa aagttaataa aaccgatttt gttctgcttt gtcctgtatt
    32641 acttgctgcc gattattgga acgattttgt atgccagctc cactaaatgg tcaaaatcgc
    32701 ttttacctag tgattttacc ttgcaatggt tccaacagct gctgacggac agggaattta
    32761 ttgctgcggt gggtcgctca cttttattag caggtgtggt cttggtgacg attctgttgt
    32821 tgatgattcc caccattatt tggattcatt tgtatttccc tcgtttgaat cgttggctgg
    32881 aaaagctgct cctgctgccg tatgctttac caggagtgat tttggtaacg gctttgcttc
    32941 gaacgtatgc tgaaactggt atcccaatgt ttgtagtgtt ggtaggtgca ttgtttatta
    33001 cggcgttgcc gattgtctat cttagtctta acaaccagat gcgcttaatt aatctgaagg
    33061 aattagtgga tgcagcagaa accttgggcg ccccgatgtc tacgattatt atccaggtgc
    33121 tgtttccaaa catccgtatc ggtgtgaccc tagtttctct gatgattttt tcttcggttt
    33181 ttggggagta catgctgacg aacctgttga ttggcggtcg atttcagacg gtacgcatct
    33241 atatgctgcg gcggatgaac gaaaacggcc atttggctag cgctgtgatg gttttgtatt
    33301 tgctgtttat ggtgggaatt gctttaacta cctttatgct gacttatcga caaaagcaac
    33361 agctgtccct taagcagacg agggaagaga agcagtcgaa aaagaagccc ttaaaggagt
    33421 tgtgacggaa aatgttttta gaaatacatg atctcaatct gttttttgat gaaaaacaga
    33481 ttttagctat tgatgaaatt cagattgaaa agggtgagct ggttacttta ctaggtccca
    33541 gcgggtgcgg aaagtctacg ttgctgcgct gtatcacggg attggaacaa ccaaagagcg
    33601 gtgagattgt gctggacaat gagaatattg ccgataagcc tacgaaggat cgcaatatcg
    33661 gctttgtttt tcaacagtat gcattgtttc caactatgac tgtttttgaa aatgtagcct
    33721 ttggtttgaa ggtaaagaag ctgagtcctg aggtgattca ggaaaaggtt tttgagatgc
    33781 tatcattggt ggatatgacg gagcaggcag ataaaaatgt ccagtttctt tctggcggtc
    33841 aacgacaacg ggtggcactg gctcgctcat tggtcactga accgaaagtc ctgctgctgg
    33901 atgagccatt aagtgctttg gatgcccgaa ttagaaaaca gctgcagcgg gatttgcgcg
    33961 ctatccagca atcgctaggg atgacgatga tttttgtgac tcatgaccaa gaagaggcga
    34021 tgcgaatcag tgatcggatt tttgtgatgg aagctgggcg ggtggctcag gtttccacct
    34081 cgaaggaatt gtatcagaat cctcagagcc gatttgttgc ggaatttatc ggcaactata
    34141 atcgtttcga atggtatgag ctgaatcagt atacccacga gttttccgct aagggcaatc
    34201 gctgcattta ttatttaaga ccggagctga ttcaatttga accggttcct cagggggtta
    34261 agattccggt tctatggaag gaatcattta ttttaggcaa cattcaacgg tatgtttttc
    34321 aaacgctgga gggcaaagaa attttagtgg atcggttgaa cgatcgggaa gagaaaatta
    34381 gcgatgcctt atacattcag ctgaaagata ttctagcaat ccctgtggaa attgatactc
    34441 agcattttgc acaacaaagc tagtgtatag tcggcaaaca tttctggctc tttgtcaaat
    34501 aggactgata gagtgatata agaacatcta aggtagaatt gattttctgc tttagatgtt
    34561 tttttatgtt taataagtga tcagatgatt gattaagaaa attctggttc tcatcctaac
    34621 ccgtaagcta ttcgtttcaa tgctttgatg tgggtatgca gattttctat tttgccattt
    34681 gagtaaggca actctaaggc taaacgaatg ccggattcat agtttataaa cgcttttttt
    34741 atatgatgca gttctcttgg aaccgacttg ggcattgttt ttacaagctg aaagaagatg
    34801 tccgcttctt tgtcataaaa agcttgaaga atttcttgat agtaagcata agctattcgt
    34861 agttcatcag aagtagaaag tagacgttct acgacttcac tttcggttaa ataggcccaa
    34921 ccaaaattac gccattttgt ccatttatca taaacaagcg tgtcctgtcg tttgatcaga
    34981 agtcgagata aagccttcac ttgtcgatag tgtttggctt gtattggatc gtttcggtcg
    35041 aagcttttca tgactcatag tcaaatatcc ttaaaactgc gaatgaggtg cttgacgatg
    35101 tgaaagcgat ccacaacgag tttggcatga ggaaagcact cttttatcag caaagcataa
    35161 gaggcgttca tatctgttac gagtattttt acgtttaaac gtgcacgtcg ttcaaattgc
    35221 ataaaataag aaatgagatc tttcttctta cgtgaaggaa gaatatccag taatttccca
    35281 gtatcgccat ccatacaaga aaaagaatag ggaccgactt gatttttcaa tgaacgaaat
    35341 tcatctacca atgaacagcg aggcaaccaa tttattttca cgtttgtcat ggggagcaga
    35401 gaagcgagtg ttcgcgaaac ggttgaccaa gaaacgccgc aatgtttaga aatcgtcgtc
    35461 attgcttgtt tttcagtcaa ttcctccaat attttataat gtacttgttt ggcgataaaa
    35521 cagttttttt caacaatgta ggtattcgcc gtaaaatagg tgtgacagcc acgacagagg
    35581 taccgttgct ttgccaaagc aagataagtc cgttgattcg cacacttatt gagaaggacc
    35641 agcgattttt tctttccgtt cttaacgatc agcccatgtt gattcacctg tttacactga
    35701 ggacagggct gaatcgtttt aatgagcgtg gcagaaacaa cgatactgtt gattgaatgt
    35761 atttttttct tctcgacatg agtgatttga atgtttccat ctttgattcc tagtaatagt
    35821 ttgataagat gaagatcagg catacagaac gctcctttga ttgtgttgtg gtgattcaat
    35881 tctaacggag cttctgtatg ttttgttttt ttatgctcaa aaggactgat agaatgattt
    35941 actatcagtc ctagaaatta tagcgccaca tttctttcac ctttgacttt tcagacggca
    36001 gtttttatgc tgatactgta gagagagcag gacacagctt ttgcttgttt tgggtaaggg
    36061 ggaaagaaga tgaccaaagc acttattttt gattttgatg ggacgatgat tgacagtgaa
    36121 tggatgtttt acgagagtat tcatcactat ttactgaagc ctatttactg gagcagttcg
    36181 gctataaaat tccttttgca gactatcaac aaggtgttgg gacggcagca gaactgtcct
    36241 tttatgaagg gataagtcaa gcggttggga gaccagtgga tgctgaacat tttgagcagc
    36301 ggatcagcag cactggaaaa tcggagtagt ctcaattctg aactgcggga gctagactat
    36361 ttttttgaag cacatccgat gattaaggaa aaaattgatt cctttgtgac gatcgatgat
    36421 cttcaggtcg gcaaaccaga tccagaaggt tatttgttgt gcttgaaacg gctgagggtt
    36481 gaacaggctg ttgtagttga ggatagtcca gtcggtgccc aagcagcacc gcatatgaca
    36541 gttgatgtac aagcgttgga tgcagatttt ttcgccttta gcgggcataa aatgtgcggg
    36601 ccgacaggaa tcggtgtatt atatggcaaa cgtcaattgt tagaacaaat ggagccagtc
    36661 gaattcggcg gtgaaatgat agattttgtc aatctttacg atagttcatg gaaagagctg
    36721 ccatggaaat ttgaagctgg tactccgaac attgcaggag caatcgatta cttgaatgag
    36781 attggtatgg agaatattca tcgttatgag caagaactgg ttgcctacgt tttacctaaa
    36841 ttacaagcga tcggcggtat caccatttac ggaccgcaag atcctgaaca tcatactggc
    36901 gtggttgctt ttaatttgga tggcatccat ccccgtgatg tggcgactgc tctggatatg
    36961 gaaggtgtcg ctgtacgttc aggacaccat tgtgcacaac ggttcatcga cgatttctgt
    37021 ttgactaatt ggtcgtttaa acagtcgatg ataatgccgt ttgagcggct ccaatgtcgt
    37081 ggaatctttg agtaagagtt tccaatatcg cttgagccga cggtacttct tctgattttc
    37141 agattacgtg attgattttc gtacagttct atgagaatcg cctgcttcag ttcctttgtt
    37201 agttgatgat gttcatcaac taagtccgtt ttcgcagaaa aggtctgccc acaatcatag
    37261 catagaaaac gggtacgttt taattctaaa atagtcaact tttctttgac tttcaacatc
    37321 tgagtacgtg tcgtatagga accgttgcgg ataatacgaa tcgatccaca gtgttcacaa
    37381 tgggaaggtg agtcatccaa tctcccttta ataaactgcg cttgaacgcc tttatattct
    37441 ttttcaatca gccattcttc atcaaaaaat aaatgtttat ctgttaatcc gagtaatttt
    37501 ctagtatgat tatccataga gcgactcctt tggtagggtg atgttttggt cgactaaatt
    37561 ttaccaaaag tgagtctctt tttgagttga aacgaagaaa aagtgttagt agaaaatcgc
    37621 cttcgatttt ccaacaacac aaaatattat agaagccttt tttctaaagg atttcaaggt
    37681 gtctgtttgc atttattaaa aaaaagaaaa agtattggca acagaaggcg tcaccaacac
    37741 tagatattat agagccataa tatgctgtat aatatctagt gtataggctt aagtggaggt
    37801 atatatgaaa atattaactg ttgaagatga taatatgata agagagggaa taagtgaata
    37861 tctttcagaa tttggatata ctgttattca agctaaagat ggaagagaag ccttgtcaaa
    37921 atttaatagc gatataaatt tggttatctt agacattcag atacctttta taaatggttt
    37981 agaagtgttg aaagaaatta gaaagaaaag caatttacca attctaatct tgactgcatt
    38041 tagtgatgaa gaatataaaa ttgatgcatt tactaattta gtagacggat atgtagaaaa
    38101 gccattttca ttgccggtct taaaagctag aatagattct ttaattaaga agaattatgg
    38161 acatttagag aagtttgaat ataaggatct atcggttaat tttaatagct atacagctaa
    38221 aataaatggt gaagaaatag atgtaaatgc aaaagaacta gaagtattaa aatgtttatt
    38281 ggataataat ggacaagtgt taacaagaat gcaaattatt gattatgtat ggaaagatag
    38341 cgaagaaact ccttatgatc gagtaataga tgtatatata aaagaactta gaaaaaaatt
    38401 acaattagac tgtataacta ctataagaaa tgtaggatat aaattggaga gaaaatgaaa
    38461 aaattaaaga tatttccaaa aatgttcata caaatatttt ctgttcttgg aataataatt
    38521 atattagttc attcattaat tttttttatc tttcctaaaa catatttgga gacgagaaaa
    38581 gaaaagattc ataatatggc aaatgaaatt tctagtaata tgaatggaaa agaaataaaa
    38641 tatatagaac aaactttgga gttttattcc aagagtagtg aaataaaagt attcataaaa
    38701 gaaaaaaata ataagaatga aatacaaatc aaagataata taaatgttaa tttagaaagt
    38761 gatagtaatt ctttgataat tgaagaaaga gaaataaagc ttaatgatgg taaaaaaaca
    38821 aatctacaat ttgtttctac agctgatatg caaaaagatg cgaaagattt aagccttaaa
    38881 tttttaccat attctttatt aatatcaatt ttattttctg ctattatttc tttaatttat
    38941 gcaaaatcaa taaaaaataa tatacaagaa ataaaaattg ttactgataa aatgatgaaa
    39001 cttgataaaa aaatgagttt aaaagttagc tctaatgatg aagttggaga attaaaacaa
    39061 caaattaatg atttgtattc tactttatta agaacaattg acgatttgga atttaaaaat
    39121 aaagaaattt taaaattaga aaagttaaaa tatgactttt ttaaaggtgc atcccatgaa
    39181 cttaaaaccc ctcttgctag tcttaaaata atactggaaa acatgaaata caatattgga
    39241 aaatataaag aaagagatat ttatattaat gaatgtattg aaatcgttga tagtttaaca
    39301 aaaaatattt ctcaaatatt atcagttcat tctatagaaa atttgaataa tgatgaagaa
    39361 tatttgaaaa taaatgatac attagaagac atattaaaaa agtatgaaat attagcaaat
    39421 caaaagaaaa taactgtcaa taattatata ttagacgaga atgtttatat aggaaaaaca
    39481 gctttaaaga ttattctatc taatttgatt agtaatgcgg taaaatatac tgatgtaaat
    39541 ggggtaatta atattgggat agttaatgat tggttatata tagagaattc atacggtaac
    39601 aataaaattt cgaatatgga taaaatattt gatgttaaat ttgatttaaa taaggaaaat
    39661 agtaatggat taggtttata tattgtaagt aatattctga ataattacaa tatagaatat
    39721 aaagtattgc aggatgaaga attttttatc tttaaaataa aaatattttc ttaattaaga
    39781 tataattttg caatagttat tgaaaaatag agacttat
//
LOCUS       DAYNVV010000019        39680 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.019, whole genome shotgun sequence.
ACCESSION   DAYNVV010000019 DAYNVV010000000
VERSION     DAYNVV010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.019"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(148..2301)
                     /locus_tag="ACGXWR_001168"
     CDS             complement(148..2301)
                     /locus_tag="ACGXWR_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HFK0802751.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(2595..3443)
                     /locus_tag="ACGXWR_001169"
     CDS             complement(2595..3443)
                     /locus_tag="ACGXWR_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFK0802752.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(3667..5607)
                     /gene="thrS"
                     /locus_tag="ACGXWR_001170"
     CDS             complement(3667..5607)
                     /gene="thrS"
                     /locus_tag="ACGXWR_001170"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HFK0802753.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(5944..6123)
                     /locus_tag="ACGXWR_001171"
     CDS             complement(5944..6123)
                     /locus_tag="ACGXWR_001171"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016862 - intramolecular oxidoreductase
                     activity, interconverting keto- and enol-groups [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxymuconate tautomerase"
                     /protein_id="HFK0802754.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(6170..7993)
                     /locus_tag="ACGXWR_001172"
     CDS             complement(6170..7993)
                     /locus_tag="ACGXWR_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFK0802755.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            8271..10550
                     /gene="helD"
                     /locus_tag="ACGXWR_001173"
     CDS             8271..10550
                     /gene="helD"
                     /locus_tag="ACGXWR_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase recycling motor HelD"
                     /protein_id="HFK0802756.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(10643..11290)
                     /locus_tag="ACGXWR_001174"
     CDS             complement(10643..11290)
                     /locus_tag="ACGXWR_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802757.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(11469..12188)
                     /locus_tag="ACGXWR_001175"
     CDS             complement(11469..12188)
                     /locus_tag="ACGXWR_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFK0802758.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(12319..13470)
                     /locus_tag="ACGXWR_001176"
     CDS             complement(12319..13470)
                     /locus_tag="ACGXWR_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HFK0802759.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(13687..14427)
                     /locus_tag="ACGXWR_001177"
     CDS             complement(13687..14427)
                     /locus_tag="ACGXWR_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFK0802760.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(14431..14754)
                     /gene="rsfS"
                     /locus_tag="ACGXWR_001178"
     CDS             complement(14431..14754)
                     /gene="rsfS"
                     /locus_tag="ACGXWR_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HFK0802761.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(14811..15404)
                     /gene="yqeK"
                     /locus_tag="ACGXWR_001179"
     CDS             complement(14811..15404)
                     /gene="yqeK"
                     /locus_tag="ACGXWR_001179"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HFK0802762.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(15388..16038)
                     /locus_tag="ACGXWR_001180"
     CDS             complement(15388..16038)
                     /locus_tag="ACGXWR_001180"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HFK0802763.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(16048..16359)
                     /gene="yhbY"
                     /locus_tag="ACGXWR_001181"
     CDS             complement(16048..16359)
                     /gene="yhbY"
                     /locus_tag="ACGXWR_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HFK0802764.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(16375..17484)
                     /gene="yqeH"
                     /locus_tag="ACGXWR_001182"
     CDS             complement(16375..17484)
                     /gene="yqeH"
                     /locus_tag="ACGXWR_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HFK0802765.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(17481..18008)
                     /locus_tag="ACGXWR_001183"
     CDS             complement(17481..18008)
                     /locus_tag="ACGXWR_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HFK0802766.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(18188..18973)
                     /locus_tag="ACGXWR_001184"
     CDS             complement(18188..18973)
                     /locus_tag="ACGXWR_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HFK0802767.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(18966..19835)
                     /gene="accD"
                     /locus_tag="ACGXWR_001185"
     CDS             complement(18966..19835)
                     /gene="accD"
                     /locus_tag="ACGXWR_001185"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HFK0802768.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(19836..21215)
                     /locus_tag="ACGXWR_001186"
     CDS             complement(19836..21215)
                     /locus_tag="ACGXWR_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HFK0802769.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(21223..21642)
                     /gene="fabZ"
                     /locus_tag="ACGXWR_001187"
     CDS             complement(21223..21642)
                     /gene="fabZ"
                     /locus_tag="ACGXWR_001187"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFK0802770.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(21667..22143)
                     /gene="accB"
                     /locus_tag="ACGXWR_001188"
     CDS             complement(21667..22143)
                     /gene="accB"
                     /locus_tag="ACGXWR_001188"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HFK0802771.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVISEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(22146..23381)
                     /gene="fabF"
                     /locus_tag="ACGXWR_001189"
     CDS             complement(22146..23381)
                     /gene="fabF"
                     /locus_tag="ACGXWR_001189"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HFK0802772.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGTKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(23400..24137)
                     /gene="fabG"
                     /locus_tag="ACGXWR_001190"
     CDS             complement(23400..24137)
                     /gene="fabG"
                     /locus_tag="ACGXWR_001190"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HFK0802773.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(24149..25066)
                     /gene="fabD"
                     /locus_tag="ACGXWR_001191"
     CDS             complement(24149..25066)
                     /gene="fabD"
                     /locus_tag="ACGXWR_001191"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFK0802774.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEATPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(25173..25397)
                     /locus_tag="ACGXWR_001192"
     CDS             complement(25173..25397)
                     /locus_tag="ACGXWR_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFK0802775.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(25450..26412)
                     /locus_tag="ACGXWR_001193"
     CDS             complement(25450..26412)
                     /locus_tag="ACGXWR_001193"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HFK0802776.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(26422..26862)
                     /locus_tag="ACGXWR_001194"
     CDS             complement(26422..26862)
                     /locus_tag="ACGXWR_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFK0802777.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            27168..28133
                     /locus_tag="ACGXWR_001195"
     CDS             27168..28133
                     /locus_tag="ACGXWR_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFK0802778.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(28190..28420)
                     /locus_tag="ACGXWR_001196"
     CDS             complement(28190..28420)
                     /locus_tag="ACGXWR_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HFK0802779.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(28506..29393)
                     /locus_tag="ACGXWR_001197"
     CDS             complement(28506..29393)
                     /locus_tag="ACGXWR_001197"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFK0802780.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(29482..30705)
                     /locus_tag="ACGXWR_001198"
     CDS             complement(29482..30705)
                     /locus_tag="ACGXWR_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFK0802781.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(30722..31768)
                     /locus_tag="ACGXWR_001199"
     CDS             complement(30722..31768)
                     /locus_tag="ACGXWR_001199"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFK0802782.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(31932..33659)
                     /gene="ptsP"
                     /locus_tag="ACGXWR_001200"
     CDS             complement(31932..33659)
                     /gene="ptsP"
                     /locus_tag="ACGXWR_001200"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFK0802783.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(33659..33925)
                     /locus_tag="ACGXWR_001201"
     CDS             complement(33659..33925)
                     /locus_tag="ACGXWR_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HFK0802784.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            34404..36638
                     /locus_tag="ACGXWR_001202"
     CDS             34404..36638
                     /locus_tag="ACGXWR_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFK0802785.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            36786..37106
                     /locus_tag="ACGXWR_001203"
     CDS             36786..37106
                     /locus_tag="ACGXWR_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFK0802786.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(37311..37535)
                     /locus_tag="ACGXWR_001204"
     CDS             complement(37311..37535)
                     /locus_tag="ACGXWR_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HFK0802787.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(37733..39313)
                     /locus_tag="ACGXWR_001205"
     CDS             complement(37733..39313)
                     /locus_tag="ACGXWR_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HFK0802788.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
BASE COUNT        11136 a         8568 c         6888 g        13088 t
ORIGIN      
        1 ttttgtcaca accttttttg ccgagtaaac ggtgttcaaa agccagtttc tcggtatgaa
       61 gtcaaattta agcaaaaatg tgagaagcta ttttcacaaa atttttcttc atactcgaaa
      121 ctaagcggct ttttcacgac ctctttttta ttttgccatg aacatatcat aatacgcgtc
      181 cattatttct ttagcaatcg tcaagtttat gtggtcttgt tcgtctaata agttcggcaa
      241 gacaacactg atggcaattt ccggattgtc tgttggtccg tatgccacga tattactatt
      301 gactgtcgca atatctggat gaccttccgc aaccgtttct gcagtccctg tttttgcgga
      361 aaggtccatt ttcgcactgg ctaatggttt ggctgttgtg taaggatcgg taccatggac
      421 aacttggtgg aatccttcac ggaggatcgc catattttct gcagaaatat tgaccgtatt
      481 ttctactgtt gtgccaattt ctttcttcac ttcacccaag tttccatttt cgtcattgcc
      541 atagatcgct ttgactaggt gcggctgtac tcgtttcccg ccattagcga ctgttgaagc
      601 atattgagct aattggattg gtgtatatgt gtcaaactgt ccaaatgcca aatcggtaaa
      661 gttacctgga gcataccatt ctttgccatt atccgcattg aacttcttca tataatcaac
      721 agaacgtgag atcccaggag attcattcgg caaatcgatc ccagtcgttg taccaagacc
      781 aaactctttg aaagagtctc tcaattgctg ataagcttta gcttcttcat ctaaactagg
      841 tagtcccatt ccaggtgtat agtctagtcc taacatcttt aacgccactt tgatcatata
      901 cgtattagaa gacaattccg atgctttgac tgcatcaaga gcaacttgtc cgcttcgatt
      961 aaagacagag cttttttctg aagcaccttg cagacgaatc ggctcatcaa tcaaaacttg
     1021 atttccgctg atcgcgttac ttgcccagcc tgctgtcaaa gtaccagcct tgactacaga
     1081 ccctggatca aaggcgctag taatcgtgcc taaagcattc tcggtgattt ctttggaacc
     1141 ttgttcatga ctgaaaccag tcattgctag cacttctcct gtctgaggat tcatagccac
     1201 tgcataagca ccaggcgaat actgtgcttt gccgttgttg atcaatgttt gataattcct
     1261 tttcaaaatt tcttctactt ttgattggaa ttctgcattc atagataaca ttaaattaga
     1321 acctttttcc ccagagaaga tttctttttg attcgaaaca tttccttcat tatcaaggga
     1381 aacttcatat tgggttttgg ttccttgcag gacatcttca tattgttttt ccaaataact
     1441 ttgtcctaca cggtcattcc gagaataacc ttttgctagg tatttctctg cttcatctgc
     1501 tggaagtcct tgcttttcag tcgtcacact gccaagaata cttttcagtg aacttgctgc
     1561 attatattct cgtgtccagt ctgtgccagt cgaaactcct ggaagttcag aagcgcgttc
     1621 tgccacaaca gctaactctt gatcagtaac accagagttt ttgatataga cagtgtttaa
     1681 ttcatatgca ctattcatcc gtttaaagat ggtagcaatt tttaattgct cctcgtttaa
     1741 attaatctca tcagctgtga ctttattgac catcgcacta tattgttcgc tgttccctaa
     1801 ttgcttttct tttgccgaaa gtctttttgt ggcttctttc aaatgtttgg gatcagccag
     1861 ccaaaaatct tttttatctc tatctgtcag attttcatct accggaacat cgatcagcga
     1921 gttcagcttc gttgcgattt caagcaaatc tttagccgta acttgtgttc ctctcgtata
     1981 tgtgatggcc tgattcgctt tattcgtaac taaagctttt cctgtggagt cgtagatcat
     2041 tccgcgagga gtactttctt ggaccgtaat cgtagaagta gacttcactc gcgcctccat
     2101 ctcttcgccg ttcacgatct gcaaataacc caatctagca atcaacgcaa caaataacgt
     2161 aaatataatg aaaaaaagaa aatttaagcg aaaaggaaca tgggaccggc gaaacgtttt
     2221 gttcttaggt tcttgtgcac cttttcttat tttttctaac caagaagtat ttaatatttt
     2281 tttcataaaa tctttcatca tttcctatcc ttccgcctat ttacattcat gcttcattgt
     2341 acccaaaaac ttcttaataa aaaagaaaaa atgggcggag caagaaattc tttacctaat
     2401 ttcaagataa aatcaacttt ttgtttcaca gcaatcactt aaagttacat atccaactat
     2461 ttttttcatt aaaaaataaa cttatttttg aaaattatgt tttcttaagt cgtgaaacac
     2521 tttgatggat catttatttg tggaaaacta cgttttgtta ttctaaaaaa cttatataaa
     2581 aaatagtaag gtttttattt cgaatccata aaatattctt ggattgcttc tcgtgttttt
     2641 ttcacttttt cgctaagctt ttcgttttta gccatataga aataaaaaat gatatcgatc
     2701 gtagcaaatt gggccaaaag tgaattagtt gccgcacttc gattcgtgat ttcttttggt
     2761 ctagatgttt gtacgagtac atcggctatc ttgctaagcg ggttatttcc aaattgcgtc
     2821 aacgcaatga tttcgatatt catgcttttc gccagctcgg ctaatgcgac tacatctgca
     2881 cttctacctg agtttgaaac aagccaaagc actttctttt tctcattgct gacaagttgc
     2941 gggagcaaga cgtggatatc tttttcaaaa atgattggct taccgacacg agaccatttt
     3001 tgcagaatat cttctactac taaagaagag gcgccaaccc catataaaaa aacagtctct
     3061 gccgattcca aacactctac gactttttgg atcgtttctt cttctagaat atctactgtt
     3121 tcttttatcg ctacttgtgc attgttacca agtttgtttt tgatagagta aaaggactca
     3181 tttgcttcta tatcactaaa accttcatcg attccagtct gtagttctgt tgaaatcgtg
     3241 attttgaagt ccgtcagact ttgaaaaccg atttttttgg aaaaacgtac aactgtcggc
     3301 gcactcaacc cggaagcttc tgctaattca ttagctgtca ttgtagggac cttctcaata
     3361 ttaccgataa tgtagttggc caactttttt tctgctgaag aataatcttc catcatactt
     3421 tcaatacgac taattacgct cataagttcc tccacccttt taatgatagt ctatgtaagt
     3481 ataccatatc agacccttat tcacggtcgt atactggata aaaaacaaaa aaacaatccg
     3541 cccaacagaa tatcttatcc catcaatccc acagattcta ttgagcatct gtgtctttga
     3601 ggaatacctg ttatctattg ttcggattgc tttctatcta ctactttttt acaggaaatt
     3661 tacctattag ttttctctgc tgtaattttt gacttctgct tccatagcat caataaagat
     3721 attcaaatct tctacagctg tttctttact tccataacga cgtacgttca ctgttgcatc
     3781 ttccaattcc ttgtctccaa caactaattg gtaagggatc ttttgtgttt gagaggcacg
     3841 tatcttatag cccatttttt cattacgatc atcaacttct acacgcaacc ccttcatttg
     3901 caaacgttct ttgatttcat aagcataatc gccatgtgca tcaacagaaa cagggatgat
     3961 tgttgcttgt ataggtgcca accatgttgg aaaagcgcct ttgtatactt ctgttaaata
     4021 agcgacaaaa cgttccattg tagaaacaat tccgcggtgg ataactactg gacgatgcgt
     4081 attttccccg tcttctccaa catatgtcaa atcaaagcgc tctggcaata agaagtctaa
     4141 ttgtatagtt gataatgttt cttctgtacc aagagctgtt ttgacttgaa catctagttt
     4201 tggtccgtaa aaggctgcct cgccttctgc ttcaaagtaa tctagttcta attcatccat
     4261 agcggctttc agcattgctt gggctttttc ccacattgcg tcatcatcaa aatatttatc
     4321 tgtattgttt ggatcgcgat agctcaagcg gaaacgataa tctgtaatat tgaagtcagc
     4381 atatactgcc accatcaatt caagcgtacg tttaaattca tctttgattt gatcaggacg
     4441 aacaaatgta tgaccatcat tcaacgtcat ttctcgtaca cgttgtaaac ctgacaaagc
     4501 acctgatttt tcatagcgat gcatcattcc taattcagcg atacgaattg gtaattcacg
     4561 ataagaatgg atcgtgtttt tgtagaccat catgtgatga gggcagttca ttgggcgaag
     4621 aacaagcatt tcgccatctc ccatatccat tggcgggaac atgtcttctt gataatgatc
     4681 ccagtgtcca gatgttttgt acaactcaac atctcccatt attggtgtat atacatgttg
     4741 gtaacctaga ctaacttctt tgtctacgat ataacgttcg atcgtgcgtc ggattgttgc
     4801 cccttttgga agccagaatg gcaaaccaga acctacttct ggggaaacca tgaacaagtc
     4861 aagttctttt cctagtttac gatggtctct ttcttttgct tcttcacgga gacggatata
     4921 ttctttcaaa gctttcttgt caaaaaaggc tgtcccgtat acacgttgca tcatttgatt
     4981 gtttgagttt ccacgccaat aagcacctgc cactgataat aatttaaata cttgtatacg
     5041 gccagtggat ggaacatgtg gtccacgaca caaatcgatg aattcgcctt gttgataagc
     5101 agtaatcact tcttcttctg gcaattcact aatcagttct actttgtacg gatcacttgc
     5161 aaaaatttct aatgcttcct gttttgaaag aacacggcgt tcgatcggca gattttcttt
     5221 gacgattttc atcatttctg cttcgattgc cggcaaatct tctgcagtta cttggttttg
     5281 tccattatct gtatcgtagt aaaaccctga atcgatagct ggtccaacgc caaagtggat
     5341 atttggatag aggcgacgca tggcttgggc catcaaatga gctgctgaat gacggactaa
     5401 gccaagtgca tcttcatggt ctggtgtgat gatctcaata cttgcatctt cctcgattgg
     5461 acgagtcaaa tcaacgagtt ttccgttcac tttaccagct aaagcttttt ttgctaagct
     5521 ttttgaaatg ctttcagcaa ttgccaatgt tgttgttcca gactcaaatt ctttgactgc
     5581 accatctgga aaagtaattt ttatcataat agtttcctcc ttgaaatgtt ttgattgatc
     5641 agatcatcaa gctgaaaaac aaaaaaatcc tagcatctct tgaaaagaga tactaggacg
     5701 aaaagttcgt ggttccacct aatgttcaaa cgcaaatgcg ttcctcaagc gttgtaacgg
     5761 tccgaccgcc cttgcttcaa caagggtttc gaaagtggtc atcctttggt tttctcctgg
     5821 aaaagtttca gcctagcttt tcctctctta tcgaagactc tcaaattcag ttggctttct
     5881 catcaatcaa ttatgtgttt atttaaccac taataaatag aaaaatcaag tgggaaacta
     5941 aacttatttt ttccattccc catttacacc gtatgttcct tttttcatct cattgatgat
     6001 gacatggatg tgttcttttg gtgcctgcgt gtttttatga acagcttccg tgatatcttt
     6061 catcatattt tctaattgtt ccggactgcg accttctact aattcgacat gtacgaatgg
     6121 cataatgctc tctcctcttt ctgatcgttc ttttttcaac tcgattctat catactatgt
     6181 ttgtcttggg tactgaatca ggaaaaatgg ctggatcttt ttttgctctc aaggcactca
     6241 aaatagagac cgtatccacg acttcttgca aaacagctcc gaataatgcg gggattagtc
     6301 ccgtacttgc aattaacatc aaaaaaatac aaataaagat gccaatcagt acagactgtt
     6361 tcgctattct catcgtatct cttgaaatca ctactgcttt tgctacacgc aagagatcat
     6421 ctttcaagat gaccgcatct gcactttcac tagcagctgt agaaccatga gcccccattg
     6481 caataccgat atctgcagca gcaagtgctg gtgcgtcatt cacgccgtct cctaccatcg
     6541 caacaggtct ttgatcttta gggatacttt ctaaaatggt cagtttatct tgaggcaagc
     6601 tacgggcatg tacagaatct aattggactt tttctgcaat cgtttgagca atggcagatc
     6661 catccccggt gatcatcatc aaatttttca catcaagttt tcttagctcc ttgattgtct
     6721 ttgctgcttc tgggcgaatc tgatccgaaa ataggatcgt tcctgcaaaa gatcgatcaa
     6781 ttgttacata gattgctgta ttggacgttt ctatttcttc agctgaaaca aaagaggcac
     6841 gtccaatctt tacttcatga ttattgacta ctgcttggat tccttgaccg gtcacttctt
     6901 tcagttgact aacaggatac agttggctgt ttttcacgtt gttcactaac gaacgagcta
     6961 agatatggct agattcctgt tctgcactag ctgcatacag aagtagctct tcttttttta
     7021 ttccattgac tggctgaatc gcctctactt ccaatatccc tttggtaagc gttcctgttt
     7081 tatcaaaagc aatcgttttt gtacgtgcga gcttttcaat cgttgttcca gtttttacaa
     7141 cgatcccgtt tttacttgaa cggctcattc ctgcaactaa agcaatgggc gcagctagaa
     7201 tcagtggaca aggtgatgcc actaccagta cctcagcaaa tcgtaaaggg tcttttgaga
     7261 accaccaaga aataccaccg atcaaataag caatcaacgt gaaagggact gcataacgat
     7321 cagctaaacg gacaaatcgg gcaggctttt cttttgattc ttcgactagt ttaataatca
     7381 tttgatactg gctgtctgcg gcacgttttt cagcgatcat ttggatcgat ccgtctccat
     7441 ttaaagaccc tgacataatc tgatctccag gtttcttggt ttccgggcgg gactcacctg
     7501 tcaaagaaga ttcatcgacc gaagattctc ctttggtcac tcgaccatct gcgggtacaa
     7561 gttcgccagg cttgactagt aactggtcat caatatttat ttcatcgatt actatatcct
     7621 gcaattttcc ttctttgaat cgatgggcaa ttcttggggt gttatctaac aaagactgca
     7681 gttctttacc cgctcgttta ttcgcgtaat cctctagact atctccgccc gtaagcatga
     7741 tcaatatcat caaactagcc cagtattctt tgacggctaa tgttgcaagg attgcggtaa
     7801 tcgctaatac atctacgcca tatcttcctg aacgtaacgt cttgatcatt tccaaaaaca
     7861 tcaagaaggc gagaatccct ccagtaaatg cgacaatcgc aaatgcaagg gccggctggt
     7921 gaaaaacaaa ttcacttaat aaagctatcc caccaataag caaagtaagt aaaaattttt
     7981 tgaaatgtgt cattgttttt tctcctcttt tatgtgactt agagaggtta gtaataaatt
     8041 tccagctgcc tctttcatct taagcatagt ccttgactag cactttttaa aacaataggc
     8101 cttaattgaa aacaactatc actatcagcg tttccaaaat tcatcagttc tacaaacaaa
     8161 aatattcagc aaggattact ttttcgattc atcagttaaa aagtaccttt tttcgaaaaa
     8221 ctatgctata cttttaattc gttatttacg gcggaaggag caaacatgcg atgaatgaga
     8281 aacaactaga acaaacgcac gtggatgaaa cgatcgaact aatccagatc gaacaaaata
     8341 tgctggatac aaaacaacaa gaattgactc aggaaatgaa tcattcgaca aaagacacag
     8401 ctaatcacaa gattcgagct ggttccaatg aagcttttta tgaatctgct gttgaatatc
     8461 gccaacatga gcaggaattg cttttgaaat accatactct tgaagcacag caaaaacgcc
     8521 tgcaaacgtt gtctgtcatg aaagatagtc cttattttgc ccgtatcgac tttaaagaag
     8581 accgtgaaac agaaacatta tatctaggta tcgcttcttt aagagatctg gcagaagaaa
     8641 caatcgttat tgactggcgc gcaccaattg ccaatcttta ttatgaaggt gagattggtc
     8701 ccgcatttta tgaaactgaa acagatagaa tagatgtcga tctgcagttg aaacgacaat
     8761 ttaaaatcca agaaggacgt attttatcta tggtagatac gtcggaagta atcaatgatg
     8821 actttttgct agagatattg gatgaatcat caagcaacca tatgaaaaac atcgtctcta
     8881 cgatacaaaa agcacaaaat gcaatcattc gggacacaac aagtaaagta atgctgattg
     8941 aaggaatcgc cggaagtgga aagacatccg ctttgcttca acgtattgct tttctgttgt
     9001 atcataatcg caagtggctc gaggctgaaa acgttcttct attttcaccc aaccatttgt
     9061 tttctgatta catctcgact gtattgcctt cattaggtga aagcggcgtg cctacacaga
     9121 cattcaaaaa ttatttggtg cagctgctgc cagagttttc tttactagat gaacagcaac
     9181 aagaaagtgg ttttttgcta ggggaaaaag atccgataca agtgatgaaa agcggattga
     9241 ccttagtcga tcagattgat cgctatatcc aaggcatcac aaactacggt cccttgttcc
     9301 gtgatatgaa aataaatggc cgtacgatcc tatcaaagga atcgattcgc caatggtata
     9361 aagaaacaaa tgaacaatta cctttacatc atagactttc tctattacaa acgaagctcc
     9421 tgaaaaaatt aggcggtctg caaaaagacg aaacacgtca gcaatgggtc aaagatctgg
     9481 cggaagaaca gctccaagaa ctatacgcaa cagatccaaa tcttgaatat acagaacaaa
     9541 aggagcgttc attacgtaaa aaactggcca accaaatcgt acgtaaaaga ttccgtcgaa
     9601 tccatcgagg gatcatgaat tatcaatttg tcaatataac gaaacaatat ctccactttc
     9661 tacaaactgt gccactttct cttctaacac gacataaaat cagcgagacc aggtggcagg
     9721 aacatttgac aactgttcgt acacacttgc gtcaaagaga attgcgtcaa gaggatgctg
     9781 tactattctt tttactgatg cgccgaacat atccagtgac ggttacacac aaagctcgct
     9841 atatctttat tgatgaaatg caggatttcg caccatcaca agtggcattg ctgcaagcct
     9901 tgttcccaaa agcaaatttg actttctgtg gagatctaaa tcaaaatgtc tttggaaatg
     9961 aaacgatcgt tggatcattg gaagaccttt tcgtggaccg tgaagtcact cgtttccaat
    10021 taacgacaag ctatcgctcc acaaaagaaa tcactgattt tgctaatcat tttattgtga
    10081 aagaacatca agtagaaaca acagcaagaa aaggagacct tcctttgctc atccaaggaa
    10141 caacagatga tatcaaattg aattggttag cagataccat tcgaacgact cagggaaaag
    10201 cccggtattg gcgtacagca atcatagcta aaacacaaga agaatgcgaa gctctttatg
    10261 ctcaactgcc agacgagttg aaacaacaag tccagctgat tttaaatgag agtgacttta
    10321 tgaagcgttc cattatttta cttccagcct ttttagcaaa aggtctggag tttgaccgag
    10381 ttttcttgtg ggatgtagat gcagaacatt tttcttctca gcaagacaaa ttgatccttt
    10441 acaccatgtg tacacgtgcg atgcatgaat tgaccctttt tacctccaat aatgaaagtc
    10501 ctttgttaaa caatatggat atttcatctt atgagaaaaa agtactgtaa gtaaaaagac
    10561 aactgctatc attaatgtta gcagttgtct ttttatttac aataataatt gcagaaaaag
    10621 taattcaatc atttaaggtc atttattcta tatataaatc caaatctgtt tcaggatatt
    10681 ttaatttgac aagcgaaata atcattttca gttcttccat gttttctgga tattctgggt
    10741 caaatacctt gctatgacgg ccaatcccgc cattgtcgat caatcggtaa attcgattcc
    10801 attcaatgaa ttggtcaatt gattggaaat tgctgattgg atagccgcca caatccaaaa
    10861 tctctgatac acgaaatgct aggtatgcac tatcgatcac tttatttttt ttcgtgtcta
    10921 tcttctcatt tctttcgata agaatttttt caggacgatg tttcaagctc cactctaata
    10981 gtagaaagaa agcctccatc cgatactctt cttcaaataa ccgaaaggct gaatcagaac
    11041 gacgaaaaag cagcggaatc agataatttt gtctataaat cagcattggt gcgcggtcca
    11101 ccatacactc taaataacgg ttcagatacc ctgtaccgac atagtttcct aatcgatagc
    11161 cttcaacgcc gaatcttgcg tatttttgcg ctaattttga acaatcagtt acgttcacag
    11221 ctaactcttc tactttgcgg taaccgctta agatacgttc aaaaggttct aaagtgattt
    11281 ttgcttccat attcttcccc gtccatcttc cacatacttc atatcatttc acatgatact
    11341 tatgctctca tcataccaca ggttgaatta gaaaagaaaa taaatcacac aaaaaagcaa
    11401 gacaatctgt tagtgagatt gtcttgcttt tcgaaaaaga ctgaatactt ttcgttaaaa
    11461 ctggttgctt agtcttctaa tgccacatta tggaacacat gctgtacatc ttctagatct
    11521 tccagtgcat caatcatttt ttcaaatgtt tcttgatctt ctggagatag tgttacctcg
    11581 ttttgaggga tcatttggat ctcagcgatt gaaaaatcag tgattccttt ttcttttaat
    11641 gcttcttgta tactatggaa atccgctact tcaccgtaaa cgatgatttg tccttcttct
    11701 tccattacat cgcgaacatc gatgtctttt tccattaggt attcaaggat ctcgtcagcg
    11761 tcttctcctg caaaagcaaa gattgctgta ttgtcaaaca tgtaagaaac cgctccggaa
    11821 acacccatgt tcccgccatt tttcccaaat gctgcccgta cgtctgctgc tgttcgattc
    11881 acattgttcg tcaatgtatc aacaatcacc attgagccgc ttggtccaaa tccttcatag
    11941 cgcaattcag agtatgtttc atctcctgca ccttttgctt tttcgattgc tcggtcaata
    12001 atatgttttg gtacattata agttttagcg cgatcaatga cgaaacgtag tttttggttt
    12061 gcatgcggat caggatcacc tgattttgct gccgcgtaga tttcaatccc aaattttgca
    12121 taaatccggc tattattagc atctttagca gttttctttg ctacgatatt tgcccattta
    12181 cgtcccatat tttcacttcg ctttctgatt tgatagtttc ataacgcaaa aacgtcctgt
    12241 tccattatac ttgtgaatca cgattctgtg aagctttttt tctttcttcc ttcattcttc
    12301 tcatttttag tcaattatct atactcggat tgggatttgc ccgaaattct gttccggaat
    12361 attgcctccc aattgataga tttgatcact tctaactaac agttccgctt cttgtgcctc
    12421 tttttttccg attcgggaat aaatagaaat ctcttttttt tcttttaaga atcttcttcc
    12481 agcatcggta aatccaagta gtcgaagata atttttattt tgttggacag gaatctcttg
    12541 ctttttgata ttcagcaaga cataacaaga taatcgttgg atccgtgtcc atgtatatct
    12601 ttttgttttt acctttgaca caaaatcctc aaaactatca gcagttgcag ctgctgtttt
    12661 catgcgcgat tctattcctt cggtcatctg atagatatct gtcagttcca gcaaagtaga
    12721 agataacaac cgataacgca aatacggcca ataagattcc caagtctgca gcgaacaagt
    12781 tgaaagatct tcttctgtct gaggcggcac aagtccagct attctttttc cttcttctaa
    12841 cgcatggcga atggctgttg cactggctat cctctgatct gtgatgattt tttcatgata
    12901 gcctgcactt ttacgtcgga tcggatgtaa ttccataggg tggacatact tggcattttc
    12961 ctttgcataa cttaatccca agatatgatt tggcgaagaa aaatcaagcg taatatcggg
    13021 atacagactg cgaaaaacct cagtcatttt ttgcggataa ctatacgttt gatcagacag
    13081 ttcttgaaat gcctcttcta tcctatcttg attctcttgg acaaagcgtc cgaaactgct
    13141 gtaatcaaac gaagtctctt cttctgttcc aaaacacaaa ctgtcacagt ccagtgtttg
    13201 caagattttt actgcacctt tagcaaaata gtcagctgac tgaaccgccc attcgacggg
    13261 aagctccact actaaatcca caccattttg taaagcttca ttcgcgcgat gccatttatc
    13321 gatgatagcc ggttcgcctc tttgcaaaaa attcccgctc attacagcaa tgacgacctc
    13381 tgctcctgtt atttttcgtg ccatttccac atgatagcga tgtccattgt gaaaaggatt
    13441 gtactctacg ataatcccgc agcttttcat gcgcatcctc cttcatagtt atcgataaaa
    13501 aagaaataga gacaagtaaa aaaaggcaaa aatcggaaaa aatacccgaa ctatataaac
    13561 tattctcgca aacacaatac ttctgcgacg aaaagctgca ctgcaagagc aatgcctata
    13621 tcgttcggat atataattta tgttgaagat ttattctttt cttgttaact cgagcaggca
    13681 aaaccgctag tctttgtatg ctacaaagaa ccagcgcttt gatttctctg atgctgcttc
    13741 gtctgtaaaa tcagaaaatg cttcgacttt cgaaaagccg ctgttttcca gcattcttaa
    13801 ataactttcc aatggatagg tacgctcttg atgtagttca tcttcacgaa taaatcgacc
    13861 agacccttct tgttcttcaa cgaaaaaggt aagaaaatgt tcgatgctgt gtttctcgct
    13921 tcctggataa ctatcccaca aaaaagcaaa attatcccct tgataatgat agctatattc
    13981 tggaaaaacc tcatctactt gataggtgga gtgtacgtca aataaaaatc ggccattttc
    14041 ttctaacgct tgatagactt catcaaacac ttgctgtacc tcttgtctat ttttcatata
    14101 gcacagcgaa tcagaaaaac aggtaattgc ctgatattgt ccgatttctg ataaatcgag
    14161 catattgcct tccacaaatt ggatcgatgc gtcttcttca tatgctcgct ggctggcaat
    14221 catcaacatc tcttctgaaa ggtctaaccc tgtcacttta tatccatctt ttgcaaaggc
    14281 aaccgctaat gctccagtac cgcatgccag ttccaaaata ttttttgtgt cttcttgtaa
    14341 atgacgtttc gaaaaagcta accattgctg ataaagtgtt tcgtccatca cttcatcgta
    14401 aatgaaagca aatgtttcat aagccatatg ttaatccaac cattcactaa gatcgactag
    14461 cggagcatct gaccatagtt tttccagatt atagaaattt cgttctggcg catggaaaac
    14521 atgtacgatc acatctccaa gatcgatcaa tacccatttt ccgccttctt ttccttcaat
    14581 acgttttact tcatatttgt tttcttcttc tttatcaatg atttcttctg taattgcgtt
    14641 gatttgacgt tcgctatttg ctgaacagat catgaaataa tctgccaaca aggaaacatt
    14701 tcgaacgtct aaagcgataa tgtcttctgc ccgttttgaa tctgctgctt caatcgcaat
    14761 ttttaattgt tctttactat ctatgatgat ttcctcctaa tatgagcagc ttattttttt
    14821 gctacccagt aattatatgt ttcgattgtt tttggataaa tctgttgttc ttgcgcaagc
    14881 aaatgggcca atgtatgttt tgtttcaaat gctacagctt cgtctagatc agcccatgca
    14941 atggctcgtg catcttgtac cccaggaaaa tctcgacctg gttcaatata gtctgctaca
    15001 taaatgattt tgtcaaggag actcatctta gcagccccag tcgtatgcac ccggattgca
    15061 tgaagaatct ctgcatcggt gattcctaat tcccgctcta caaacgaagc gccaacaaga
    15121 ccatgccaga ttgcattatt ataattcaat aactccggat caaaaccgtc tcttacgatt
    15181 accattttga actcctcatc tggtcgttct tttgcataat catgtgtcaa tgcagcaata
    15241 ctagcttttt caggagaagc accgtatttt ttggcaagag ccacggctgt ttcttctact
    15301 ccaagcacat gcttgaagcg ttgttcgctc attctcatct gtattttttg catcaggttt
    15361 tctctagaat aagcagtata ttcattacta tagtccatat tcatacaacc cttcattttg
    15421 aatataatca attactttat ctggaacaag gtagcggata gaacagcctt ctttgatctt
    15481 ttgacgtatt ttcgtggaac tgatgtcgat ctcaggtaca tctacccaaa ttacaggata
    15541 tggagtatcc gttgtgtatc ctggtcgacg tatacccaca aagttgacca tagaagtcag
    15601 ctcatcgatt ttataccatt ttggcaaata ttctaccata tccccaccga taataaagta
    15661 ataatctgta tccggattgt tttgcgtcaa ttccttcata gtatcatagg tgtaactttt
    15721 cccaccacga gctaattcaa tcgtttcaat ctgcaaaaaa ggattgtctt ccaccgctaa
    15781 ttccaacatg ttgagtcgat gttttgcatc aatcgtctgt ttctcatcaa catgaggtgg
    15841 ctgataagaa ggcatcaaaa atacgcggtc aagacctaaa ttccggccag cttgttcagc
    15901 catcactaaa tgtgcaaggt gaacgggatt gaatgttccg cccaagatcc ctacttgctt
    15961 tttcttctct aagaattgag gcatttcttc aggaaataat tgtgaacgaa caaatgtctt
    16021 agcttgcgta ttcatcatgg tcactcctta tattgctttt acttcttttg atagcctttg
    16081 atacttttct tttgtggaag gtttgtataa tacaataaca cgtccaatga tttggacgat
    16141 ttcgcaatct atttcttttt ctaatacttg agctgcttct tctgcaatct catctgtatt
    16201 ttgaagtaac gatactttga tcagttctct tttttctaaa gcttcttcaa tttgaacgat
    16261 cattgctgaa ttgatcccac cttttccgat ttgaaaaatc ggctgaagat gatgcgcttt
    16321 gctacgtaaa aaacgctttt gttttcctct taaactcata attttccttc ttccttaaat
    16381 caatgctttg cgtttcaata catctacacc ctttggcgcc cagcccgcaa ttactactgg
    16441 cgctgttaca gtgatccagc ctagaccggc aaaaacgatg tctgtttttt ctttcacaga
    16501 aaactcaaaa cgaacaagct ccggaaatgc ctcgacttca tcaggacgag gaggctgtaa
    16561 taatccacct acatgttttt gataaaattc gtctgctttt tccagtttcg ttcgatgaat
    16621 atttacatca tttgacacat aagcaataaa tgaagcacga ttgccgctga taaaatcaaa
    16681 tcttgcaagt ccgcccaaga aaagtgtttg cccttcattc agctgataaa ctttaggttt
    16741 gatttctttt aacggtgcaa tgatccgcaa atctttttta cctaagtagt gcgccatttg
    16801 atggcgatgg ataattcccg gtgtatcaat caaaaaatgc ccgtcatcta aaggaatctc
    16861 gattttatcc aaggtcgttc ctggaaactg cgaagttgtg attacatctt gtactcccgc
    16921 tgtatttttg atgatttgat tgataagcgt cgattttccg acatttgtta ctccgacgat
    16981 atagacatcc cgtccatcgc ggtattcttc gattttttct aatagttccg tcatctcatg
    17041 agatttctta gcactagtta ataatacatc tactggacga attcctgctt cgtaagcacg
    17101 ttccttcatc cattgtgtta atttagtttt tttcaatgat ttaggtaata tatccacttt
    17161 gttcccaact aaaagtactg gattgtcacc gacaaaacgg tgtagtcctg ggattagtga
    17221 accattgaag tcaaaaatat ccaccacatt gacgatcaat gcatcttttt gccctaattc
    17281 attcagtaag cgcaaaaagt cgtcatccgt caatgagaca tcttgggtct cattataatg
    17341 gcgtaatctg aaacaacgct gacaatagac ttccccggaa gctaaacctt tttccaaagc
    17401 cgtttgcggc gtgtatccta attcaccggg tttgtttgtt tgtataacgg caccacagcc
    17461 gatacattgt aattcttctg tcattcgatt ccacctcgcc agcccatatc agggtgtttt
    17521 gctaatagat aggccataat tcttttttcc caaaaacgat taaattgtgt cttccaacta
    17581 tctgttgcga taatgggttt tacaaggatg ctacgtatcc ctgcacgatt ggctccacgt
    17641 atatcagtca taatctgatc gcctaccatt actatctcat catctgctaa atccaattgt
    17701 ttctttgcta tgttgatccc tcttgctaaa ggtttcattg ctcgtgcaac atacaaaaga
    17761 tcaaattttt caatcgctcg cgcgacacgt tttgaattat tgtttgaaac aacaacaaca
    17821 gggattcctg catttttcat ttctaaaatc caagtaagca actcttctgt tccatctgga
    17881 ttattccatg caatcaacgt attgtctaaa tcggtcaata ctgctttgat gcctagattc
    17941 tttaattggg caggtgtaat ctgatagatg gcttctacca tccatgttgg tttgtaattt
    18001 gaaaacatgc tgtctcctca tctgcaaaaa atgaaggagc acataaagta ctcctcaacc
    18061 ccgtattata ctgcatatca gcaaaaaaaa ctacctctat actcgttcgt ctttcagaaa
    18121 aagcatttct ttacaaaatg accaaaaata aagattgatc acagaaaaat ttagaaacaa
    18181 aaaacaacta atattggcgg aacctcttgt atcgtttttc cagtaattta tgctgatcta
    18241 atcgaacaag ttccgtcaat ctttcaatca acgctttttt cataatgtgt gcgactttat
    18301 atcgtggcaa ctgctcgccg ttgaacgttt caggaataac tcgatcaacg attcctaact
    18361 cgcgtagttc tggcgcagta attttcatca actcagctgc ttctgcggcg cgactaccgt
    18421 ctttccacaa aatcgacgca aatccttctg gagaaagcac agcataaatc gtttcttcca
    18481 gcatccagac ttcatccgct aaacctagag caagggcacc gccacttcca ccttcaccaa
    18541 tgatgatggc gatgatcggt acctttaaat cagacatttc gagcagattt ctggcaatag
    18601 cctctccttc gccgcgctct tctgctccta caccgcaata tgcacctgct gtattgatca
    18661 aggtaatcac cggtctattg aacttttccg cttgtttcat cagtcgtaaa gcttttcgat
    18721 agccttcagg atggggagaa ccaaaatttc tgcggatatt ttcctgcaga tcccgtcctt
    18781 tttgaatacc gatcactgtt accggtttgc catctaatcg agcgattcca ccaacaatcg
    18841 cttcgtcatc tgcaaataaa cgatcaccat ggcattcctc gaaagaatcg aagatctctt
    18901 caaaaaaatc caagcttgtc catcgttctt tagctcttgc taactgaacg acatcatgtg
    18961 ctgtcttatc cacgatctat ccatcctttc tgtgtatgca attcaagaag cgtatggatt
    19021 ttctgtttca attccatgcg gggaacaatc tgatcgacaa aaccatgaga taataagaat
    19081 tcagcctttt ggaaatcttc tggaagttcc tgcttgatcg tctgttcgat gacgcgtctt
    19141 ccagcaaaac cgatcaagct ttggggttct gctagaataa tatcgccttc cattgcaaaa
    19201 ctggcagtta ctcctccggt cgtcgggtcc gttaaaacag ttagataaaa aagaccttca
    19261 ttgctatgcc gtttgacagc agcagagatt tttgccatct gcattagaga aaagattcct
    19321 tcttgcatcc gtgcgccacc tgaagctgtg aacaagacga ctggaagact ttcctttgtt
    19381 gctcgttcga ataatctggt gatcttttct ccgacaatcg ttcccatact tcccatgata
    19441 aaattaggat ccatcactcc aataatgaag ggaatcccct gaatggttgc tttaccagtg
    19501 aggactgctt catgaagtcc tgttttatct tgcatttttt taattttttc cgtatattcg
    19561 ggaaatgcta gcggatcttt ggttacaaga tccgtatccc attcttcaaa acttttttca
    19621 tcaataatca aagctagacg ctgccatgca ccgattcgaa aagcgtatcc gcaatgaggg
    19681 catacttttt cttcaccgat gtctttcgta taaaggatat gtttgcaatt tggacacttt
    19741 gcccacatgt tatcaggaac agatggcgag ttagcaggtt tgctctctct attaggattg
    19801 atccgaatat atttcttttt cttaaacaga gccatctatg cgcctcctat ctccgtttct
    19861 ggtgtccaat tcggtaaaaa ttcttcttgt aaaaatgctg tgctgtaatc acctgctatg
    19921 actgcaggat gactaatcaa atccatctga aattctgcgt tcgtgatgat tccttctgtg
    19981 ataaattcac ttaaggctcg ctgcatcttc attaatgctt caaaacgcgt atttccatgg
    20041 acgattattt ttgcaatcat tgaatcataa tatggcggga tcgtatatcc cgggtaaact
    20101 gcactgtcta ctcgcagtcc catcccacct gctggaagca gtaagttttg gatcttccct
    20161 ggagaaggag caaaatggaa agcaggattt tctgcattaa tccggcattc gattgcgtgt
    20221 ccttggaata ctacttcttc ttgacacaca ttcaaaggct caccggctgc tatctccacc
    20281 tgttttttta ctaaatcgat tcctgtgacc atttctgtta ctggatgttc cacttggatt
    20341 cgagtattca tttccatgaa ataaaaatcg ccttcttcat ccatcagaaa ctcgatcgtt
    20401 ccggcatttt cataattgac tgctttagct gctcgaacag cagcgtctcc tagtgcttct
    20461 ctttttgttt gtgagatcac tacagaagga gattcttcca gtactttttg attgttgcgt
    20521 tgtaaagaac aatctcgctc gcctaaatga atgacatgac caaatcgatc acctaagatc
    20581 tgaacttcta tatggcgagc aggataaatg attttttcca aatacatatc atcatttcca
    20641 aatgccgctg ctgcttcttg ctgagctgaa gaaaaatgct gtgggagctc ttcttttgat
    20701 tgaactttcc gaatgccttt cccgccacca cctgcagctg ctttcagcat cactggataa
    20761 ccaattctgt ctgctatttc caatgcttct tctactgtag ataatacacc agtacttcct
    20821 ggaatgactg ggacatttgc ttcttgcatc aattgacgcg cattgatctt atttcccatt
    20881 gcatcgatcg ttgcactttt aggaccaata aatgtgatat tgcactcttc acacatggag
    20941 gcaaatcggc tattttcaga taaaaaacca aatcctggat gaattgcttc ggcttttgtc
    21001 acgattgcag cgctcagtac ttcctgaaca ttcagatatg aatcaacggc ttttgccggg
    21061 ccaatgcaga ttgcttcatc tgctaactgt gtatgaagtg cttcggcatc tgcttctgaa
    21121 tatatcgcta cggtttggat ccctagttcg cggcatgcac gaatgatacg tacagcgatt
    21181 tcaccgcggt tagctatcaa tactttagaa aacatatttc acctatccaa tcataaaggt
    21241 taattccgct tcggctactt ttttaccgtc tactttagcg attcctttgc ctattccggc
    21301 tgaagctttc actttcaata tctcaacttc aaggtataag gtatctcccg gtgtaacttt
    21361 cttacggaat tttgctttgt ccaatccgcc gaaataagcc gtctttccct tgaattgttc
    21421 aagagaaagt aatgcaactg ctcctgcttg agccattgct tcaacaatca atacccctgg
    21481 cataacaggt tcttctggaa aatgtccttg aaaaaagggc tcattgatcg ttacattttt
    21541 cttagcaacg atccgttctc cttcaaccat ttcttccact cgatcaatca aaagcattgg
    21601 ataacgatgt ggaatgattt cttttatttc ttgtatgttc attgttttcc ctctttcctg
    21661 ctttgcttat ttttgctgaa tcctaaagag tggctgtcca tattcgacaa ctgactcgtt
    21721 ttctacaagg atttctgtga tcactccgtc ggcctcacta gttatctcat tcatcagttt
    21781 catcgcttca ataatgcaga taacttctcc tttggcaact tgatcaccta cttttttgaa
    21841 agctggtttg tcgggcgctg gttgcagata aacgattccc acgattggcg aaacaacctc
    21901 gattccatca aatactgccg attctttttc tttcattatt tctggagcag ttgttgcttg
    21961 ttcagatatg acattgactg gctccgaaac tggcaacgtt tcgtttgttt gaaccatatt
    22021 catgcctcga cttgttttat ttttattcat atacaattca aattgacctt cacgcaaatc
    22081 gaattccgtt agcgaggatt gatcaaattg actgactaat tctctgattt cattgatatc
    22141 caaaattatt cctcccagcg tttcatgcac agaaccgcat tatgtccgcc aaaccctaat
    22201 gaattactca ttgcataagt aaaacttgca ggtttgcttt cgtttttgac aactgtcaag
    22261 tcaatctcag gatcttgttt ttctacattg atcgtaggtg ggataaattg atgttctaat
    22321 gccagcaaag ttgccaaggc ttcgatcccg ccggctgctc ccaataaatg tccagtcatc
    22381 gatttcgtgc tgctgacgta agtatctctg aaattttcac ctaatgcgat ttggattgct
    22441 tttgcttctg cctggtcatt ggctggtgta cttgttccgt gagcattgat atatccgact
    22501 tgttccggct gtacaccagc ttcttccatc gcaagcttca ttgctttaga tgcaccagaa
    22561 ccatctggag taggagctgt catatggtaa gcgtcacagt ttgcaccgta tccaacgatt
    22621 tctccataga ttttggcacc gcgagcttgt gcatgttcta aagattcaag aactagaacg
    22681 cctgctcctt cacccatcac aaaaccattc cgattttcgt caaacggaat cgaaccacga
    22741 ttaggatcag ttgattctga gagtgctgtt aaagctgcaa atccagcaat ccccatctca
    22801 caaatcgttg cttctgttcc tccagcaaga atgacatcag aatagccatg tttgatgtta
    22861 cggaatgctt ccccaattga attcgttccg ctagcacaag ctgttacgat agctgtacaa
    22921 ataccttttg cacctacacg caaagcaata tttccagctg ccatgttggc aatcgccatt
    22981 ggtacgaaca ttggagaaac tcgttttgta cctttttcat gtagacgaat aacttggttt
    23041 tcgattgttg gaagaccacc gatcccagat ccgatgatga cgccaaaccg gtcttgattc
    23101 attttttctt tatctaaacc gctcatctcc attgcttcta aagcagcgta gattccatag
    23161 atcgaaaaca tatccattcg tttgctatct tttttaataa aatatttatc gtaagggaaa
    23221 tctttgactt cacccgctaa ggtaatccct gtttctgaag catcaaattt agtgatcggt
    23281 gcgatgccat tcgtcccctc ttttaagcta ttcaaaaagc tgtctgcgtc atttccaata
    23341 ggtgaagtga ctccatagcc agtaattacc actcgattca tttgtttgct ctccttttct
    23401 tatccgtgca tgaccaatcc gccatcgaca ttgatgactt gtccggtgat atatggattt
    23461 tgtgctaaga aaactgctgt ttgtgcaata tcttctactt gtccgaaacg ctgcatcgga
    23521 atttgctttt ccgcttgttc cttgactttg tctgctaaaa cttccgtcat atcagttgtg
    23581 atgaatcctg gcgcaatggc attacatgta atgcctctag ttgcagcttc tcgtgccaca
    23641 gattttgtta atcctactac gccagcttta ctagctgcat aatttgcttg accaatattt
    23701 ccaatcaacc cagatacact agagagatta atgatggccc cttctcgctg cttcatcatt
    23761 tttttcaata cgtgctgcgt catattgaag gttccaatca aattgatatc cagacatttt
    23821 ttgaaatctt ctgcatccat tcgcatcaca agtttgtcat ttgtgattcc ggcattgttt
    23881 actaacacat ggatcgatcc aagcttttct tctgcttctt tgatcatttg tcccgctttc
    23941 tcataatcag agatgtcacc ggaaactcct acgcatttta caccgaatgc ttcgatttct
    24001 tctatctttt cttttggaat ctctccgcga ccattcaaaa tgatatttgc tccagctttt
    24061 gcaaaagcta aggccatcgc tttgccgatt cctcttgtac tacctgtgat aaatacattt
    24121 tttcctttta catccataac gttcctcctt atagtattgc tattgtttca tcaaatgtct
    24181 gcttattctc aacacgcaga actggtattg ttttatcgat ttttttcata aatccgctta
    24241 atacttttcc ggggccgact tcgatgactt gttcgatgcc gattgttttt aacttatgga
    24301 tactctcata gaaacgaaca ggttgcatga cttgctgttc aagtagtccc gcgattgttt
    24361 ctttcttcat tatttccgtt gttgtgttgc ttatgatagg aaaagaaggt tcagagaatt
    24421 gaatctgact taggtccttc gccagttttt ttgctgccgg ttctaaaata gctgtatgaa
    24481 aaggcccgct gacatttaga gggatcattc ttttgaaccc tttttctttt aatagtaaaa
    24541 cagcttcgtc tactgctttt tcttcgccac caatcacgat ctgctgaggt gtattataat
    24601 ttgcaggaga tacgatgccg tacttgctag cttcatgaca gctttcctcg atcgtttcaa
    24661 tcggcgcatt catcactgca accattttcc cgcttccagc tggggtagct tctgtcatat
    24721 aagcgcctct ttttgctact aacgcaactg cttcagtgaa ggatagcgca ttactagcta
    24781 ctaatgccga atattctcct aaactcagtc ctaaagctgc atctgggatg attccatgct
    24841 ccttcaataa gcgataatac gcgatgctga ctgttagaat agctggctgt gtatattgcg
    24901 tctgatccaa acgttcattt tctgtaaagc aaagttcagc catatcgtag ccgagaatct
    24961 cacttgcttc atcaaatgtc tgctttacaa cggcttcttc atataaatct tttcccatac
    25021 cttgatattg tgcaccttgg ccactaaata agaatgctgt tttcatgttt ttctccaata
    25081 tatccagaat atatgtttga ttcttcctat tcaaaaaggc cgagacattc ctatttcagg
    25141 aaatgtccca gcccccaacc taattttaat gattatgcag tttgtttttc tacgtaagtc
    25201 actaaatctt gaaccgtttt gattccgtct tctgtttcga ttttcacgtc aaattcatct
    25261 tcaatttcat tgatgatttg gaataaatcc aagctgtcag cttctaagtc ttcttggatg
    25321 tcagtagtca atttgatttc ttcagtttct tttcctaatt cttctgcgat gatttcttga
    25381 attttttcga ataccataat aatatattcc tccgatattg tttgcttttt atttttataa
    25441 tttaacagtc tacaactcca tgagaatact tccccatgtt aaacctccgc catagcctgt
    25501 aaatattact ttctgctgtt ttcctaaggt gatctttcca ctagaaactg cttcatccaa
    25561 taagataggg atgcttgcag cagatgtatt cccatattta tccatattgg tcaggaactt
    25621 ttcttgcggc atctttactt ttcgggcaat tttctcaata attctgaggt ttgcctgatg
    25681 caaaagcaga taatcaactg gtttgtcttt catgacttct tggatattgt ttgcaacgtc
    25741 tcgtacggca aaatcaaaaa tatctctgcc agtcatttgc aaataatacg aaccttctga
    25801 atcttctgaa tagaacggat ttttattttg ctggtagcca gcggtcaatg agctacttct
    25861 ggtaccgtca gctgctaatt tttctttcag caattttttc tgtggattcg cttctaagag
    25921 aatcccacct gctccatcgc caaacaacac agcagtcgta cgatcagacc aatcgattag
    25981 cttagatagt gtttcaccac caatcaccag tcccttagtt gagccgcagc ggatcatttt
    26041 ttcagccatg cttaacgcat aaacaaatcc tgagcacgca gcactgatat caaaagcgat
    26101 agcatgagtt gctcccaatt tcccttgtac ttgtgctgct acagatggtg tcgtgtaatc
    26161 gggcgacatt gttgctacta aaataaaatc caaatcttta gggtttagat ttttctgttt
    26221 tatcaatttt tccgccacta aaatgcataa atcagaagtc tcctgatttg ttacacatct
    26281 tcgttcacga atacccgtcc ttgacgaaat ccattcatca gaggtatcca tcatcttgga
    26341 aagatcatta ttagtaataa tcttttcagg aaggacgctg gctgttgcag taatcattcc
    26401 aaattgttcc attaaatatc ctcacttata gtcttgcaag aagtcgtgca agtttttcag
    26461 tgcatccagc aaggcatgct gttcctccgt agccattccg tctaagatgt tcttgaccat
    26521 ttcacgatga aaatgctgat ggacccgaaa tagtaacttt ccttttttcg ttagtcccaa
    26581 ctttacaacg cggcggtcat cttcactgcg gatacgttcg acatagcctt tttttactaa
    26641 cttgttaata gcagtggtca aggtcccaac agtaattgat agttctttgg ctacttctga
    26701 agttgttttt ttcttgtaca tcccgattgc ctcgatcgtg tgcatctctg tgattgacag
    26761 atctttgaat tgagattttt tcagctcaga ctcttcgatt gtcaaaatat cattgaagac
    26821 actaacaaga taatcattta ctgtttttaa atctggttcc atgttccacc gtccactaat
    26881 tagtttgatt atcaaatctt ttgatgttca aactatatct taactttttt caaaatgcaa
    26941 ccttaaaaga tcattttttt actatatgag ctttttttaa gattttactc atttaaaaca
    27001 actgataaat cagcatttat aatttctttt attagaaaaa tcatctatct cacatatttt
    27061 gattatcaaa gtattttctg tgaacagaac tatagaattc cctaaaactt gtccattatt
    27121 tcaaaatttg ttatagtctt tttattcaaa gcgtaaaagg agatcctatg ttaaaagaaa
    27181 aaatgaaaac tctccccatg ctgccgggtg tctatcttat gaaagaccga gatggtaagg
    27241 tcatctatgt tggtaaagca aaacggctca aaaatagagt aagcagctat tttcatcaga
    27301 ataaacagca ttcaaaaaaa gtattacgta tgattcatca tataacagat tttgatttcg
    27361 tcgtagtaga cacggaatta gatgctttat tgctcgagtg tcaattgatc caacattacc
    27421 gtccttttta taaccgacaa atgaattatt tcagtaatta taattatgta catattacca
    27481 ataagggatt tgtattaaca gatactccta cggctcgaac atacgggcct tttcgtctct
    27541 ataaaaaaat gccgtctatt ttgcgtataa tggaagaaac ttatcaaatg ccttggttgt
    27601 ctgaaattag tttgttagct ttgcgagtcc agcttcctga cctacaggaa atgacttttg
    27661 aacagaaaaa aaaggaactc caagggctgt ttcaaggccg aaataaaaag ctactgactt
    27721 acttgaaaaa aagacaacaa catttcatct atcagttgaa tttcgaaaaa gccggtatgc
    27781 ttcaaaaaga tatcgaatta gttacttatt ttattagacg gatccaggaa caaaagcagt
    27841 ttttaagaac accatcgctc accttcagca tgccattagc agcagatgag agtcagaaaa
    27901 agcactacct cgtttgttat ggtcaacttg cagaaacaat gattacctct ggtgacgttt
    27961 ctcctgactt ctattatgaa aagaaagaag ctcatttatc tttgaaacgt caattgtcaa
    28021 aagaagaaat cgatcctgta caaatcttga tcagttaccg caaaaaatta gaaaaagaac
    28081 agtttgaaat tgaactgtta aacaaaaaag aagctgaaaa gcaactaaat tagttgcttc
    28141 tcggcttctt ttaggcatct tcaacttcaa atgtcaatta tcctaaaatt tattggatta
    28201 agtcatagat ttccatcgct acgatatcga tattatcaaa ttcgtattgc tgatgagtat
    28261 ctgtttcagt taattcaaat gtatcggtcg ctttatcata agttactgta cacttctcta
    28321 cgccttcttt ttcaaaacgg cgaacttgca gttcattatc tgctgactcg accatagcct
    28381 ccagtcgttt tatgattgcg actaattgtg aatgtgtcat cggaggtcct ccttttctta
    28441 tttctgttat attgtatcaa aagcatagcc tacttgcatt gattttctct aaaaaaactc
    28501 gttttttatg attttttttc tggtattttt ccttcaggcc accaaagttt gatcaaagct
    28561 tgggttccgt cattctcaaa acctttatct gccaactctt catatagttt caatgcttgg
    28621 gtagttgctg gcaatacaag atccattttt tctgcttctt ctaatgcaat ctttaaatct
    28681 ttgataaaat gtttgacaaa aaaaccaggt gtgtaatctt cttttaaaat acgaggagaa
    28741 taattgctta aagaccagtt agctgcactt ccacctgaaa gcgtctcaat cactttcttt
    28801 aaatcaagtc cgtttttttg tgcatagaca agcatttccg tcattcctgt catcgtacct
    28861 gcaatcatga tctgattagc catttttgta tgctgacctt tcccagcaga accatgcaat
    28921 gtaaatgtcg taccaaattc tttgaataaa ggcagtactt gatcataaac ggcttcttct
    28981 ccaccgacca tgatcgtcag tgtaccattc tttgctccta agtcaccacc ggataccggt
    29041 gcatctaacg catctgcgcc tttttctttt gctgtttttg caattttttc tgccaggctt
    29101 ggtgtacttg tagtcaaatc aactaaaata tgtcctgaga tatctgcaga aaaaatcccc
    29161 gactgtccat agtagatttc ttctacatct ttggggtaac ctaccattgt aaagagaata
    29221 ttactttgtt ctgctaccgc ttttggtgta tctgcccaga tagctccttc tgttactaaa
    29281 ggatcagctt ttgcttttgt ccgattatag acagctactt cgtgtcctgc ttctagtaga
    29341 tggcgtgcga cagcacttcc catgacgcct gttccgataa aaccaagttt cattttttcg
    29401 acctcctaaa aatcaaaaat ccttgcttct atgctagtat acgctagaaa caaggatttt
    29461 ttcataaaaa atgtttgaat tttatctttt aaatgaattt aattttattt tgattcgttc
    29521 aatcgagtct tcttcttctt ttcttcgcat ctcttcttca tgataaacaa ccatgtcttg
    29581 ataaaattcg atcatagctt cgccgaaatg tgtagatgaa atatcataaa gtttagcttc
    29641 taaaactttt ggatctttag gaacttcact ggaaatataa tcaataagtg ctggtgcaaa
    29701 gtcttcgtcg gtttcaaaag ttttccctaa tgaaggatga tcgaacaatc ggttcaaata
    29761 agcatttcct tccacgacac aaggtgttcc ggctgccatc gcttctgtat aagtaagccc
    29821 ttgtgtttct gaagtagaag cactgacaaa ataatctgcc gctttataat aaagtgctac
    29881 atcattgttg tccacttctc ctgtgaactg cacaaattct tctaactgca gttctgagat
    29941 caattcctct aactcttcta cataaggtcc ttttcctacg ataactaatc tggcgttagg
    30001 ataagcggag atgacctgag gaaacccatt aatcaaggct tggatatttt tctcataaga
    30061 aatcctgctt aaagaaagaa tcatcaaatg gttttcctga agacctagtg actcccttaa
    30121 tttgctgata tcctgctgag tgatatcaga acgtttgaat ttttcaatgt cgataccagt
    30181 aggaatcacg cgaagcggtg ctattacacc atagctgcgt aatgtatcaa taacacgttc
    30241 acttggacaa actacacctg tcgtatgatt tgcaaataat ctagacaagt attttacatg
    30301 ggattgcctg atcacttttc ctttaccgat ataatgaagg tagtcttcat acatcgtatg
    30361 gtaagtatgg atcagaggta ttttcaactt cttagctacc atcttcccaa gtatccctgc
    30421 tccgaattct gtatgggtat gaataagatc tagttctagt tctttggcaa ccaaataagc
    30481 ataccacatg cctctaacaa caactcttcg atccttgaaa gaaataaatg gtacacttgg
    30541 cattcgaatc acatcttttt ccaacttatc cgcattagga tcggtcgttg taaaaatata
    30601 gacttcatgc ccatgtcttt ctaattcttg ttttaatgtt ttgatcgatg tagcaactcc
    30661 gctgacttgc ggaaagtagg tatcggtaaa aaagccgatt ttcatgtttt tcgcctccaa
    30721 actagtcctt gacctgattt acttttttta atttgctaga gactttttca ttcagtacac
    30781 tttcgtatac atttttaagt tcttcaccga ttttattgat acttcgctct tttgctgttt
    30841 gataaccggc ttgtgtcgta ctcggtagtt cttgattggt aatctgttgg atcagtcgga
    30901 taaattcttc gtttgtcttc cccatatagc agttcttgct atcttctaac cagccattat
    30961 acactggaat atctcgaaca agtacgtttt gtttgcttgc taaagcttct aaaacaacga
    31021 tcccttctgt ctcttcataa gaagggaaaa agaatagatc tgcacctgaa tacgcacctt
    31081 ctatgatctc tccacgaatg taaccaggaa acaggacatt ttcaggatga tcttctttta
    31141 caattttccg gatgttccga ggaatcgagt acatgggaac atgaccaaac caaataaatg
    31201 tgtattcggg catcttctta gcaatttcta cgaaatcaat gattccttta cgttcgaaaa
    31261 acaaaccgac acaaatgatt actttttgat ccggagacag tttgaaatat tctctgaact
    31321 tttgttcttt cattggatca gggtgatatt tctctaagtc gatcccattg gaaatagctt
    31381 gaatcggcac acggatacca tagctttcca acaactgttt tgaataaggt gttggcgtga
    31441 tcagatagtc cgctttttgg tacaatccta ccagatattt ttttacgata ggagaaagct
    31501 ggttcgatcc gataaaggaa tttcggaaat cttcctctgt agaatgcgca tgatagacaa
    31561 ctttttttcc ttctcttctg gctttattga ccatattatg actattgatt ccgtatgtat
    31621 tgatgtgcag gatgtcataa tcttcttttt catctagtgt ataagagata ccgacttccg
    31681 tcagagcacg tttttgatga tcaagcgcac gcccgattcc agattttgca agcatctttt
    31741 cactttcaaa atataataat accttcacct tacgtccccc ttcacttata tagtataaca
    31801 tagcctacaa actgtcactc aaacttaagc cctatttttg tctattctta ctgacaaaaa
    31861 cgttttctta aaaaagaaca aaaaaactgg cgtagctctt ttacaagcca caccagcttt
    31921 tgatacgttg tttattttac atattcatga acaagttcaa cgacttcttc catcatatcg
    31981 cattctttca atgcacgatc agcaagttca gccattttcg ctgtgtccaa gcgtttcatt
    32041 aaactacgcg ttttaagaat agatgtcgca ctcattgaga actcatctag acccatacct
    32101 actagcaatg gaacagctgt ttgatctcca gccatttctc cacacatacc tgcccatttt
    32161 ccttcagcgt gtgctgcatc aattacattt ttgatcaaac gtaaaattga tgggttatat
    32221 ggttggtaca agtaagaaac gcgttcgttc atacggtctg ctgccattgt gtattgaatc
    32281 aaatcgttcg tacctacaga gaagaaatct acttcttttg caaacttgtc tgctaagact
    32341 gctgctgctg gaatctcgat catgatgccg acttggatcg tatcagatac ttccttgcct
    32401 tcacttatca atttttgttt ttcttcttca aagatcgctt ttgctgcgcg gaattctttg
    32461 agtgtagcta ccatagggaa catgatacgt aaattaccat gaacagatgc acgaagcaat
    32521 gcacgcattt gtgtacggaa catttcgtcg ccttgttcag ataaactgat acgcaatgca
    32581 cgatatccta agaatggatt catttcatga ggtaattgca gatatggtag ttctttatct
    32641 ccaccgatgt ccattgtacg aacaactaca ggttttcctt ccataccttc taatacagct
    32701 ttgtaagctt catattggtc atcttctgtt gggaagtctg gagaatccat atacaggaat
    32761 tcagtacggt acagaccaac tgcttctcca ccattattat ggacaccaac tagatctttt
    32821 ggtgttccga tgtttgcagc taattcaaaa tgcttgccgt cagctgtgac agtttctgca
    32881 ttttttaatt tttcccattc tgctttttgt gctgcgtaat ctgcacctgc tttttcaaat
    32941 tcagcttttt gttcatctgt aggatcgatg attacatcgc cttcgatccc gttgacagcc
    33001 aaaatatcgc cttctttgac tttagcagta atttcttttg tcccaacgat tgctggaatt
    33061 tctaaagaac gtgccatgat agcagaatgt gaagtacgtc caccaatgtc tgttacaaac
    33121 gcttttacaa aattgcgatc taattgtgct gtatcacttg gagtcaagtc atgtgcaaca
    33181 acgaccactt cttcgttgat cattgatgga tttggtaaag taacgcctaa taagtgcgct
    33241 aaaatacgtt tagcaacgtc acgaatatct gcagcacgct cttgcatata agcattatct
    33301 tccattgctt cgaacatacc gatatacata tccgttactt cttttagcgc tgattcagca
    33361 tttacgctgt tgtctttaat attttgcttg atttgaccta ccatttctgg atctgaaaga
    33421 accatcaaat gggcatcaaa tacttgcgct tctgcttcac ctaagctttg cgctgctttt
    33481 tcacgaattt gctgcaattc ttcagtagat ttagctaatg cagcatccaa acgagcttct
    33541 tcagccgcag tatcttctac tgttgcctta ctgaatgtta aatccggttg aactagcagg
    33601 taagcttttg caacggctac accgtcacta gcggcaatcc cttttagcat ttcaaccatt
    33661 attcagataa gccttctttc ttcattgttt caacgattgc tgccattgca tcagcttcgt
    33721 cagcaccttc tgcagtaata gtaacatcag aaccttgacc tacacctaaa gacataacgc
    33781 ccatgattga tttcaagttt actgatttac ctttatactc taagtttaca tcagagttaa
    33841 atttgcttgc tgtttgtact aatagtgtag ctggacgagc gtggatccca gtttctgcta
    33901 ctacgtgaaa ttctttcttt tccatattaa tcggtctcct ttaagtgagt gttgttttta
    33961 tgtgagggtt ttctttttta gtaattcaga gaatcctaac aaatgccacc ctttcatctg
    34021 taaagattaa catttttttt cgttagatac aacagttttc attcaatttc agataaaagt
    34081 attcaaatta ttccggattc tttttcatcc ttttcttcac attttataac aaacgtgttt
    34141 atttcctttt tcttgtcgct ttctcttctc ctgacgttta tcattctttc ctttgaccct
    34201 ctttgttttc atatgaaacg aattacttgc ttcccttttt atttttagta taataagagt
    34261 caaaggtcag gaatggtcaa tagagatttc accttttcta cctcataaat ctcttaaaaa
    34321 actaggggtt attcttttac ctcatgaaaa acgagatgta aaatatggat gtacccattt
    34381 ttgtgaaagg acgtgaatga ttcatgcttt gtcaaaactg cggcaagaat gaggcaacga
    34441 ttcacttgta tgccactgtc aatggtcagc ggacacaact cgattactgt cagagctgtt
    34501 atcaaaaaat caaaaatcaa caaaatggag gtctgactaa tatggcccaa aatgatccat
    34561 ttggatttgg cagtttggac gatcttttcc gttccatgtc tcgccaaatg caacagcaag
    34621 gaaattatga gcaaacacca ccaacacaat ttggcggaaa caacaacttc aatggtggtc
    34681 agccacctca aggcaataca gaaggtttat tgggagaata cggaatcaat atcacagaac
    34741 aagcacgaca aggtgatatc gatcctgtga tcggacgcga tgacgaaatc aaacgagtca
    34801 ttgaaatttt aaatcgccga accaagaaca atcctgtctt gattggagaa ccaggtgttg
    34861 gtaaaacagc agttgttgaa ggtttagcac aaaaaatcgt agatggtgat gtaccgcaaa
    34921 aattaatgga caaagaagtc attcgtttag atgtcgtatc tttagtccaa ggtactggta
    34981 tacgaggaca atttgaagaa cgtatgcaaa aattgattga agagatccgt caagcagaaa
    35041 atgtgatcct attcatagat gaagttcacg aaatcgtcgg tgctggttct gctggtgatg
    35101 gaaatatgga tgctggtaat attttaaaac cagctttagc tcgaggagaa ttgcaaatgg
    35161 ttggtgctac taccttaaat gagtaccgca tcatcgaaaa agacgctgct ttagaacgtc
    35221 gtatgcaacc tgtacgggta gatgaaccaa ctgtcgaaga aacgatcagt attttgaaag
    35281 gtttgcaaaa acgttatgaa gactatcatc atgtaaaata tactgatgag gccatcgaag
    35341 cagccgcaac tttatccaat cgttacgtcc aagatcgctt cttgccggat aaagccatcg
    35401 atttgctaga tgaaacaggt tctaagaaaa acttgacgat ccaaatcgtt gatcctaaaa
    35461 caatcgagaa aaaactgcaa gaagcagaag aacaaaaagt tttagcttct cgagaagaag
    35521 atttcgaaaa agcagcttat tatcgcgatc agatcaataa acttcaaaaa atgaaagaac
    35581 gtcagctcac tgaagaggaa acacctgtga ttaccgaaaa agatatggaa aaaatcgttg
    35641 aacaacggac aggtattcca gtgggtgaat taaaagaaaa agaacagaca caactgaaaa
    35701 acttagcaga tgacttgaaa gctcatgtca tcggacaaga taacgctgta gatcgagtag
    35761 cgaaagcgat tcgccgaaac cgtgttggat taaacaaaca gaatcgtcca atcggctcct
    35821 tcttatttgt tggaccaact ggtgtaggta aaacagagct tgcgaaacaa cttgcctacg
    35881 aactattcgg ttcacaagat tcaatgattc gtttcgatat gtctgaatat atggaaaaac
    35941 atagtgtctc taaattgatt ggttctcctc caggttatgt cggatacgaa gaagctggtc
    36001 aattaacaga aaaagtacgg agaaatcctt acagtcttgt cttgttagat gaagtagaaa
    36061 aagctcatcc agatgttttg catatgttct tgcaaatctt agatgatggt cgattgacag
    36121 atgcacaagg aagaacggtc agctttaaag atacgatcat cattatgaca agtaatgccg
    36181 gaactggtaa agtagaagca aacgttggtt ttggtgcggc acgcgaaggt gttactcgtt
    36241 ctgtattgaa ccaattaaac aactacttta caccagaatt tctgaaccgt tttgacggga
    36301 tcatcgaatt cagtgcatta tcaaaagaaa acttgatgac aatcgtcaca ctaatgctag
    36361 acgatgtcaa ccaaatgctg gcagcacagc aacttcacat cgaagttcct acgaatgtca
    36421 aagaaaaatt agttgactta ggctatgatc catctatggg tgctcgtcct cttcgacgca
    36481 cgatccaaga acaaatcgaa gatggtatcg ctgaatttta tcttgatcac ccttctatcc
    36541 atgagttgaa agcaaaactg gataaagatg gaaaaatcat cgttacttct aaaccagaac
    36601 gtttggctaa agaatcagcc gaagaaacgg ctgaataaat ccagttttat agcgtgagac
    36661 ggtatttctt tgagaaatgc cgtctcattc ttttttcaga aaagtcaaaa tactgttcat
    36721 tttataaaaa agaaattata ataagagaaa caagcaatta aaaatacata aaagaggtga
    36781 gcgccatgaa attggtaaat gtaacaaaca gccattcccg tcttgtatta aaccagcttg
    36841 aaaacactga tgcccatcta gtcaaggtct acacagccgg aaataccact attgtctaca
    36901 ctgaagcccc tgaacataat gaaattctgc tgatcaatga caaacgtaaa atccagccga
    36961 aagaaatcga agatgctaaa aattatttct tagataaaat caaagacgcc gtttaccacg
    37021 aggatgaaat caaagtaatc gaattggcag gccttgttga aatctcgatt ccaaaacatg
    37081 aattaggcgc tacattagcc gtgtaaacaa attttgaaca taataattaa agagcgtggg
    37141 acaaaagtaa agaacacttt tgtctcacgc tctaaacacg tataaacggc gaaagcagaa
    37201 gcaactcctt cggaaataag ctgaaattca cgaaaattgc ttttcaaatt tttgtgaatt
    37261 ccagcttatt tcttggagtt aaacgcttct gtctcagcct ctttttcttt ctagcttttt
    37321 gatttttctc ttttcttttg tacttttctc ttttcatttt cagttctacg cgtgtcttta
    37381 tttttaactt tttcctcttt atggatgatt gatcgtactt tttgtgcaat ttgctcgttt
    37441 ttgtcccagt cttttacatc taataatcga cataatcgta acatctcttc ttttttctgt
    37501 ttttttcttt cacgtctttg ccattctgtt tccatgtgtc acactctcct ttctttaatc
    37561 atatgtacgc aaaataattt ttatattttt ttgattagac atttctatga ttttaatata
    37621 gtaaaaagag ccgtcacgga aaatccgtca cggctctaaa caaaatatga gaggctgttt
    37681 ttgtttggct attcttatta cttgatgcag ggcagcttgt gtcaagactt ctttacatca
    37741 aactttttaa ttttacattg ggatatttat ccgcaaacca gcgttctgca aattggttct
    37801 cgaataagaa caacggttgg tcgaaacggt cacgagccaa gatattgcga cttgaactca
    37861 tcttctcatc caaatcttct ggatcgatcc agcgagcgat tttgtgtccc attggagaca
    37921 tgattacttc ggcgttatac tcatttaaca tacgatattg gaatacttcg aattgtagct
    37981 gaccaacagc tccaatgata tattcttccg ttagatatgt tttataaagc tgaatcgctc
    38041 cttcttgaac taattgatag attcctttgt ggaaggattt ttgtttcatg acattttttg
    38101 cagtcacttt cataaacagc tctggagtaa atgaagggag ttcttcataa gcaactttta
    38161 gttttccttc gaacaatgta tccccaatct gataattgcc tgtatcatat acaccgatga
    38221 tatcgcctgc tactgctttt tcgacgtttt ctctcgaatc tgccataaat tgtgtgacat
    38281 tgcttaattt cagtttttta tttgtacgtt ccaaccagac atccattcct cgttcgaatg
    38341 ttccagaaca gattcggaca aaagcgattc ggtcacgatg ggctggattc atatttgctt
    38401 ggatcttgaa tacgaaacct gaaaattctt cctcataagg acttaccatc tgatcatctt
    38461 gtgttttgtg tccataagga gctggtgcca attcaacgaa agtctctaaa aaagtctgta
    38521 caccgaagtt agtcaatgca gaaccaaaaa atactggtgt ctgatcgcca cgagcaattt
    38581 tttcttgatt aaatgcatct ccagcctctt tgattagttc tacttcttct aagacttgtt
    38641 catataagga attttcagtt agaggatgat tttcgggaag cagtccatct tcatccaatt
    38701 ctactaatcg ttcatcctga taattttccg gacgataaaa ctctacacga ttatggtaga
    38761 tatcataaag accttctagc cctttaccca taccgattgg ccaattcatc ggataagatt
    38821 cgatatctaa tagctcttct aattcttcta acaattccaa tggttcacga ccatcacgat
    38881 ctagtttgtt gataaaagta aatatcggga tgccacgttt ttttacaact tggaataatt
    38941 tctttgtctg tgcttcgatc ccttttgcac tatcgattac catgaccgca ctatccacgg
    39001 ccatcaaagt acgataagta tcttcagaaa aatcttcatg tcctggtgta tccaagatat
    39061 ttactcgttt cccttgataa tcaaactgca taacagaact agtaacagaa atcccacgtt
    39121 gtttctcgat ttccatccag tctgatttgg caaaattacc tgtttttttg ccttttacgg
    39181 tcccggcttg acggatagcc ccaccaaaca atagtaattg ttctgtaatc gttgttttcc
    39241 cagcatccgg atgggaaatg atcgcaaaag ttctgcgatt gtccacttgt tgctttaatt
    39301 ttggattatt cataacctaa ctccatttct tccattcaat tatttatatt ttctctaggc
    39361 acagattgtc cgatctctta aagaaagaca atttcatata gggctgtgac aaaagccgtg
    39421 tagcagtctc tttttccgag taaacggcgt tctagagaca gcctatcagc aataagccca
    39481 cccaagccaa aaatacgaaa agctgttttt gcttggctgc tcttattact taatgcagga
    39541 tagctttttc acaacctttg tcaactacta caactgaatc agtatagcat ggattcagcg
    39601 aatgaaaaag ccaccaaacc ataagagtca aatatttttt tgtcagctga ctaaaagaaa
    39661 agacgtgttg cttgtttatt
//
LOCUS       DAYNVV010000020        39582 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.020, whole genome shotgun sequence.
ACCESSION   DAYNVV010000020 DAYNVV010000000
VERSION     DAYNVV010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39582
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.020"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(448..2355)
                     /locus_tag="ACGXWR_001206"
     CDS             complement(448..2355)
                     /locus_tag="ACGXWR_001206"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M13-type metalloendopeptidase"
                     /protein_id="HFK0802789.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            2485..3360
                     /locus_tag="ACGXWR_001207"
     CDS             2485..3360
                     /locus_tag="ACGXWR_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HFK0802790.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            3440..4414
                     /locus_tag="ACGXWR_001208"
     CDS             3440..4414
                     /locus_tag="ACGXWR_001208"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFK0802791.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            4594..5739
                     /locus_tag="ACGXWR_001209"
     CDS             4594..5739
                     /locus_tag="ACGXWR_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFK0802792.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            5876..6220
                     /locus_tag="ACGXWR_001210"
     CDS             5876..6220
                     /locus_tag="ACGXWR_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HFK0802793.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            6491..7777
                     /gene="efmA"
                     /locus_tag="ACGXWR_001211"
     CDS             6491..7777
                     /gene="efmA"
                     /locus_tag="ACGXWR_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HFK0802794.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(7915..8514)
                     /locus_tag="ACGXWR_001212"
     CDS             complement(7915..8514)
                     /locus_tag="ACGXWR_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFK0802795.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHCSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            8918..10039
                     /gene="mnmA"
                     /locus_tag="ACGXWR_001213"
     CDS             8918..10039
                     /gene="mnmA"
                     /locus_tag="ACGXWR_001213"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HFK0802796.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            10285..11706
                     /gene="arcD"
                     /locus_tag="ACGXWR_001214"
     CDS             10285..11706
                     /gene="arcD"
                     /locus_tag="ACGXWR_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0043858 - arginine:ornithine antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA];
                     GO_process: GO:1903826 - L-arginine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HFK0802797.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            11720..12838
                     /locus_tag="ACGXWR_001215"
     CDS             11720..12838
                     /locus_tag="ACGXWR_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HFK0802798.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(12898..14190)
                     /locus_tag="ACGXWR_001216"
     CDS             complement(12898..14190)
                     /locus_tag="ACGXWR_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFK0802799.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            14340..14900
                     /locus_tag="ACGXWR_001217"
     CDS             14340..14900
                     /locus_tag="ACGXWR_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFK0802800.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            15029..15406
                     /locus_tag="ACGXWR_001218"
     CDS             15029..15406
                     /locus_tag="ACGXWR_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HFK0802801.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            15339..17411
                     /locus_tag="ACGXWR_001219"
     CDS             15339..17411
                     /locus_tag="ACGXWR_001219"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_function: GO:0098847 - sequence-specific single
                     stranded DNA binding [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0051304 - chromosome separation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFK0802802.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(17622..18569)
                     /locus_tag="ACGXWR_001220"
     CDS             complement(17622..18569)
                     /locus_tag="ACGXWR_001220"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFK0802803.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            18815..19279
                     /locus_tag="ACGXWR_001221"
     CDS             18815..19279
                     /locus_tag="ACGXWR_001221"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFK0802804.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            complement(19341..20384)
                     /locus_tag="ACGXWR_001222"
     CDS             complement(19341..20384)
                     /locus_tag="ACGXWR_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HFK0802805.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(20761..21726)
                     /locus_tag="ACGXWR_001223"
     CDS             complement(20761..21726)
                     /locus_tag="ACGXWR_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HFK0802806.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            21960..22805
                     /locus_tag="ACGXWR_001224"
     CDS             21960..22805
                     /locus_tag="ACGXWR_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFK0802807.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            22996..24183
                     /locus_tag="ACGXWR_001225"
     CDS             22996..24183
                     /locus_tag="ACGXWR_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFK0802808.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            24189..24545
                     /locus_tag="ACGXWR_001226"
     CDS             24189..24545
                     /locus_tag="ACGXWR_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HFK0802809.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            24547..24885
                     /locus_tag="ACGXWR_001227"
     CDS             24547..24885
                     /locus_tag="ACGXWR_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HFK0802810.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    24961..25217
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            25280..26314
                     /locus_tag="ACGXWR_001228"
     CDS             25280..26314
                     /locus_tag="ACGXWR_001228"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFK0802811.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            26307..26993
                     /locus_tag="ACGXWR_001229"
     CDS             26307..26993
                     /locus_tag="ACGXWR_001229"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFK0802812.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            27017..27865
                     /locus_tag="ACGXWR_001230"
     CDS             27017..27865
                     /locus_tag="ACGXWR_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFK0802813.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            28062..28835
                     /gene="sufC"
                     /locus_tag="ACGXWR_001231"
     CDS             28062..28835
                     /gene="sufC"
                     /locus_tag="ACGXWR_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HFK0802814.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            28848..30134
                     /gene="sufD"
                     /locus_tag="ACGXWR_001232"
     CDS             28848..30134
                     /gene="sufD"
                     /locus_tag="ACGXWR_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HFK0802815.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            30131..31366
                     /locus_tag="ACGXWR_001233"
     CDS             30131..31366
                     /locus_tag="ACGXWR_001233"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HFK0802816.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            31353..31823
                     /gene="sufU"
                     /locus_tag="ACGXWR_001234"
     CDS             31353..31823
                     /gene="sufU"
                     /locus_tag="ACGXWR_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HFK0802817.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            31828..33219
                     /gene="sufB"
                     /locus_tag="ACGXWR_001235"
     CDS             31828..33219
                     /gene="sufB"
                     /locus_tag="ACGXWR_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HFK0802818.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(33314..34456)
                     /locus_tag="ACGXWR_001236"
     CDS             complement(33314..34456)
                     /locus_tag="ACGXWR_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFK0802819.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(34495..35229)
                     /locus_tag="ACGXWR_001237"
     CDS             complement(34495..35229)
                     /locus_tag="ACGXWR_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFK0802820.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            35460..35735
                     /locus_tag="ACGXWR_001238"
     CDS             35460..35735
                     /locus_tag="ACGXWR_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0802821.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            35833..37830
                     /locus_tag="ACGXWR_001239"
     CDS             35833..37830
                     /locus_tag="ACGXWR_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802822.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKIHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVGDNSVKNALIKNRGYFVKQGFTLERASKDIKKLYNVKASSSFLIYLAKGAGI
                     DETIKELILSGAGIVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(37906..38241)
                     /locus_tag="ACGXWR_001240"
     CDS             complement(37906..38241)
                     /locus_tag="ACGXWR_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFK0802823.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            38368..38583
                     /locus_tag="ACGXWR_001241"
     CDS             38368..38583
                     /locus_tag="ACGXWR_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFK0802824.1"
                     /translation="MKKVNNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPMNELFSDVFNKVNS"
     gene            38620..38982
                     /locus_tag="ACGXWR_001242"
     CDS             38620..38982
                     /locus_tag="ACGXWR_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HFK0802825.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            39028..39354
                     /locus_tag="ACGXWR_001243"
     CDS             39028..39354
                     /locus_tag="ACGXWR_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802826.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
BASE COUNT        12901 a         7060 c         8260 g        11361 t
ORIGIN      
        1 tttttataga tgaggttctc cttgctgctt ttgattggct gttcttatta cttgatgcag
       61 gacagctttt tcacaatctc tccactaaac ggtgttcaat cagctgaccc tcggtattag
      121 ctcaacaaac ggcaaaatat gaggaactat ttttccgttt ttttctctaa tactcaggtc
      181 aggacgctga tttcacaacc tctcgataaa cggtgttcaa aagccagttt ctcggtagta
      241 agtcaaattt atgcaaaaat gtggaaagcc attttcacaa aatttttctt actacttgaa
      301 actaagcagc tttttcacaa cctctaatac atggtattcc agaagtaact tcttcgaaaa
      361 ataagccgaa atgtcacaaa aatttgagaa gcgattttcc caaattcctt cttatttctt
      421 gaagctgacc acttctggca caacctctta ccagattcgc actctttttt ctggcgctag
      481 atacatagcg tcttgttccg tgataccaaa tgtttcatag aattcgtcaa ggttttttgg
      541 ttgcacgttt gctcggagtt tagcaggggc atggacatcg atttgcagta aaagttgttg
      601 gtattctttt tttgcttttg tacgccaaat cgttgcccaa ttgacaaaga attcctcgat
      661 agaaagatct gattccgttt ttgctgcttc caatgcacag cttagaccgc ctgcatcagc
      721 aatattttcc gaaacggtta attttccgtt tacttttccg tcagcaaaag gcagaccatc
      781 gaattcttcg atcattgctt gtgctttgtt ttgaaattgt gtaagatctt cttctgtcca
      841 ccagttgttc aagttgccat attcgtcaaa taaagcgccg ttattatcaa atgcatggga
      901 aatctcatga gcgataacag ctccgattcc accataatta gcagagcttg attgttctag
      961 actgtaaaat ggtgcttgaa ggatcgctgc cggaaagacg atcacattcc gaaatggatg
     1021 ataataagca ttgaccgtgt cagcactcat ttcccattct gaacgatcca ctggtttgtt
     1081 ccatttgctg aaacgatctt ttaatgtgag tttgctgaaa acaagagtat ttgaaagcaa
     1141 agtaccaccc tgatctgcag gtactgtttt gaactggtcg aataatgctg ggatcttatc
     1201 ggggtagcct acttggatac ctaagttatt taattttatg acggcttttt cttttgttgc
     1261 atccccaagc cagtcatttt cttctagacg ttttttataa acggcgatca tttttttcac
     1321 catttgttct acgtcttttt tagcagcttc gccaaaatat ttttttccgt agtaatcgcc
     1381 aactacttga tcgaattgtc cagaggcaag gtaatacgct gcttttttct gaggcattgc
     1441 ttcgtctgtt ccagacaata cgcgagaata gattccgctg acttggcgga attcttctga
     1501 tagataacca ctaagagaac gtactgtttt aatgatcatc cagcttttga ataacggaaa
     1561 atgagcttct gtcaggatgt cattcaaatg atcgaagtac actggatcag ttacgatcac
     1621 tttatctgga gttgtcccaa tcaaacccgt gacaagtttt ttcaagtcca gtttatctgt
     1681 gtatttaata aatgtatcaa aagattgcgg attatacatt ttgctgtaat ctgcgttttc
     1741 ttctgcactt tttacatgag gagcaatcaa tttatcaaat tgcactgctt gttccgtgat
     1801 tgcttctgcc tgactttttt ctttgccggc aagctctaat aactgaacag ccatatcaaa
     1861 gaaaacgcct attagttgtg caccgttggg atggtctgat gcataatacg tcttatctgg
     1921 aaggaataaa gaaggcggat aagcaaagaa ggcgttcgtt tgcgcattct tcatatctgc
     1981 atctacatcc agattaaatg gcaatggtaa tgtatccaac agccattctg gaaattgctt
     2041 attcaattcg tcgaaagact gcaatgattc aactttttcg attataggtt gaagcggttg
     2101 agcatgcaac tcatttcttc ggtcataatc gtttgccagt tgataatatg caaggaaatg
     2161 tttcattttt tctgaagaca ctttttctgg atgggcaagc agatcgtctg tttctcccat
     2221 caaaagttgg tcgatcccgt caactaaatc ttggaaaccg cctgtagctg gtttatctgc
     2281 agggattttt gctgtttttt gccattcttc attgactgct tcatagaaat cttgtttcaa
     2341 tcgttctttg ttcattcatc gatcgctcct tttttgtttc gtgtgcccat tatcttacaa
     2401 aatgaaggaa ttaacaaata gaacataaaa aattgaaaat tcgaacaatc aaactgattt
     2461 gtttttttca atccttcact tataatgaaa aaaaggaggc gatcccaact gaatcaagta
     2521 gtggataaac ctttatattt caaagtagat aaaaaaatta aaaaattagc cagcactcag
     2581 cagctgcagt caagaaaaag taaattgctt tttttagctc tggtttttga agatcaaagt
     2641 tatgtgatta tcgatcaatc aggacatccg gtagaatatt ctccagcaaa atatacttat
     2701 caagagggtc tttcttgtaa aaaatggaag ctgatcaatg aagagccaat cgagttatct
     2761 agatggatca acagaaaaga agatattccc gttttgatcg aagaaaaaag gtcaggaaag
     2821 gaactcgcaa attgctgggt gggattgcca gaagaacgtt ttttgaggta taagaaatgg
     2881 gctaccccct caggctatct ttgtggtact tacgcggcag cagttctcct tgcctattat
     2941 caagactatc gtaaggggtg gatgcttcca aatgagattc gcaagaaaaa tacggctgat
     3001 tcgttggttt tgacgaaggc attgcgtagc cagatccaac cactaggact tcctacgatt
     3061 ccttttcagg ttagtacagg gatttctagt tttttaaaga agaatggcaa tcatgagcgt
     3121 gcacgagcaa ctcttctagg ttcatggcag cgagctacaa aacgtatacg tgaaggcaaa
     3181 cctgtgatga ttggtatttt gaaagtactt ggcagtacat atggcaatca ttgggtgaca
     3241 gcgtacgctt attttgaaac tgaaacagga gaacgttatt acaaagtaca cgacaactgg
     3301 ggcgattatc ataaagtcat tcctgccagt tggagtaacg gaacagtttc acttccttaa
     3361 gaatttgctg aaattaacag aaaatcttgg aaaaatatgt taaactatcg aagaatagag
     3421 aagttttggg gaggactaca tgagtaataa gtatcaggat gacacgttga agatttttag
     3481 tttgaatggc aaccgtccat tagctgaaaa aatcgcgaaa gtgttcggaa cagaattagg
     3541 taaaagcgtc gtgaagcaat ttagtgatgg cgagatttcc atcaatatcg aagaaagtat
     3601 tcgaggggat catgtgtata tcgttcaatc aacgaatgca cctgtcaatg attactatat
     3661 ggaactactg atcatgatcg atgcaatgaa gcgagcaagt gcgaaaacga tcaatgtcgt
     3721 attgccttac tatgggtatg ctaggcaaga ccgcacggcg aaacctcatg aaccgatcac
     3781 tgcgaaattg atcgctaact tgatcgaaga agcaggggca actcgagtac tgactttaga
     3841 tctgcacacg gttcaagtac aaggattctt tgatattcct gtagataatt tatttacgat
     3901 gccgttgttt gctcattatt accgtcaatt aggtctgacg ggagatgaca tcgtagttgt
     3961 ttcgccaaaa aacagcggtg ttcagcgtgc acgtagtctt tcagaatatt tgaacagcac
     4021 attagccatc gtagatcatg cagatgatgc ttcaactgag ggtggttatg tgatcggtga
     4081 tgttcaagga aagacatgta tcatggtaga tgatatcttg aacacaggag caacgcttgc
     4141 acgagcagca aatgtattaa aagaaaacgg cgcaaaagaa gtatatgcct gtgcgtcaca
     4201 tggattattg tccgatcatg cgaaaagtat tttagacaat gcaccaatca aagatatttg
     4261 tatcactgat tctgttttca cagaagaaaa tcgtcatcca gaaaacttaa caatcgttac
     4321 atgttcagaa ttaatgggtg aagcggtcaa acgcatccat gaaaatacac cgatgagtcc
     4381 gttattccgt ctggaagaaa aagaattcga ataaacaaaa aaaagaggga aagaagttgt
     4441 gacagaagtg agcagcttca aggagctgcg acaagacttt tgtcacagct ccttttttct
     4501 atgcccatga aacgtcctct agacaaaaat gagctcttct ttggtttgtt cgctatttta
     4561 tgctagaatg tgcctagcaa taatttggaa gggatgaatg aagtgaaaac tatttatctg
     4621 gatcatgcgg caactacccc catgcatcca caagtaattg aagcgatgac ggcaatcatg
     4681 caagacacgt ttggaaatcc ttcaagcata catggatttg gtcgccacgc gcatgaaaaa
     4741 ttggaaacag caagacaaat cattgcagac agtctgcaag caaaacctca cgagatcatc
     4801 tttaacagtg ggggaacaga aggggataat acagctatct tagaaacagc gttctcgcgt
     4861 caaaaagaag gcagacatct aatcactaca gctatcgaac atcctgctgt tcttaatacc
     4921 atgaaatatt tagagacaaa ggggtttgac gttacatatc tgcctgtaga tgaaaaaggg
     4981 aatctgtcga tcgaagaggt caaaaaagcg ttacgagaag atacgatctt ggtctctgtg
     5041 atgtacggga acaatgaaat cggaaatttg atgccaatca aagaaatcgg tgaactttta
     5101 gcggatcatc cagcttattt ccatacagat gcggtacaag cgtacggaaa ccaaacgatc
     5161 catccagaag aattaggaat cgatttatta agtatctctg ctcataaaat caatgggcca
     5221 aaaggcgtcg gtttcttata taaacgagac ggagtaaata tccctgcatt gcttttaggc
     5281 ggggagcagg aagaaaagcg gcgtgcaggt acagaaaatt tagcagggat ctggggtatg
     5341 gcaaaagcag ttgaactgct gtcacctgaa gaacgtgaag cacgtaacaa caaatataaa
     5401 ggattccagc aattgattct tgatacatta gaagcaaacg aaatccctta tcaagtaaat
     5461 ggtgatttaa cgaataaact ccctcatgtg ttgaatcttc gcttaattgg cgaagcaaat
     5521 gatttgctac tgatgaagct tgatcttaat ggggtcgcta tttctactgg ttcagcttgt
     5581 acagcaggaa atatcgagcc ttcacacgta ttagaagcaa tgtatggaga agatacaccg
     5641 atactaaaag aatccatccg tatcagcttt ggtttgggaa ataccgaaga cgacatccag
     5701 tatttccttg atcaattagt tcgtgctgtc aaaaaataac tagtgaagtc attcttatat
     5761 gaacagatgt ctgagagaac gccttcattt tttagggaac ttaactgaaa aacctagtaa
     5821 aaatcaggat aaacttttat aataaagaga aactaatttt atcgaggtga aaatcatggc
     5881 atttgaaaca acagcaacgg tactgggcgc accaattagc tatcgtttgc atcctgatgc
     5941 aaaaagatat acattgcgcg ataatggatt tacagaaaca aacggaggca attatcaatt
     6001 gatccgacca ttagatgcca cgccgcaaag caaagaagga ttcaaattaa aaatcactgt
     6061 atcaaaagat attcaaacat tgaaaatgtc gatcactaca gcaaatggat tgaaagcagt
     6121 caatattttc aaagatccaa aacagaaaat gagccaagat aaattttatt ttctgatgga
     6181 tgggatgatt agccgtgggt tattcgaaaa agtcgaatga tctgtggata taaaaagaca
     6241 actagttttg aaacggccta ttgttagatg actaactttg taaggacgac gcaaattagt
     6301 tgtctttttt atttttaaat ttaacacatg ttgttatttt taatattttg ctgatttatt
     6361 gtttctaagt aaagaaattt aaattgaaac gattgttatt tagggaaaaa ggtatttttt
     6421 gaaaaaagaa tcccgtataa tgattgttgt gcaaacgcta tacaaaatga aaaagaaaag
     6481 agggatgttt atggaaaatg aacagtcggt cgttttaacg aattggaaga gaaattattt
     6541 gttcttttta tcgggacagt ttttgtcagg aatcactagt atggtcgtcc aatatgcgat
     6601 catctggtat ttgacaagag aaaccggttc ggcgacaatt ttgagttttg ctactttact
     6661 aggaatgatt cccatggttt tactaagccc atttgtagga ccgctagtgg atcgctggga
     6721 taaaaaagct cttttgattg tcacggatat tattgtagcg attttcgcgc ttattttagc
     6781 agtagtcgga acgatttcag aatccttccc gatttggcta gtttttgtgt ctttgtttat
     6841 gcgttcggtc gcacaaacat tccaaatgcc aacgatccag tcgattatgc cgacaatcgt
     6901 tccatcttct cacataacaa ggacgaatgg acagttagga atggtccaat cagcgaattt
     6961 catcattgcg ccagctctag gtgcggcttt gttttcagtc gttcctgtca attaccttat
     7021 tttattagat gtattggggg cagtttttgg tgtcggctta ttgatttttg tgaagatccc
     7081 aaaagtttct cctgaaatat tggaagttcc gcttactatt tttaaagatg caaaatttgg
     7141 gctgcagcaa ttgatggata ataaagggtt atggtacata acgatcaatg gtgcatttgt
     7201 gatgctgttg ttcatgccag caatcagtct gtatccattg atgacgctag attactttgg
     7261 tggttccgtt ggacaggcgg gagcagtgga agtagtctac gcagtcggaa tgctcttagg
     7321 cggtgcactg atcagtttta taggaacatg gaaagaccga atgaaaccta ttattatagc
     7381 ctacatcatt atgggcctga cgatcggtgc aagcggattg gttccaaacg atagtcaagg
     7441 gttcttgtac tttcttatct tgaatgcagg agcaggttgt gcaacgccat atttcaatac
     7501 actgctgatg gcaatgatcc agcagagtta tgaatcgaat gttttaggtc gtgtcttagg
     7561 gaacttcaac tctttgatga acctggcagg tccaattgga ttattatttg caggaccatt
     7621 agctgatcgt ttaggggtag aaaaaatgtt cttgttttcc ggaatcggga ttttattatg
     7681 cggaatcgtt ttatttttaa cgtcagctgc ccgaaattat gataaagaat tacagaaaaa
     7741 actggtaaaa gaacaccatg agcaaaaaga cgaatagtat ggaatggagt tgtgacagaa
     7801 gtcttgttac aactccattt ctgatcctaa tgttcctgtg gcaataagcc tactcaaatg
     7861 aaaaatatga gtaattatct ttatttgttt aatacttgat atagggcagt tttttcacga
     7921 cctatcgtac ttcctctttg cttcatagat ttctttgatt tgttgctcag ataacggagt
     7981 gccaaatggt agtttttcct ttaagagttc tctttccggt gcgtctacgc ctacattgac
     8041 atcgttctcg ataggtacgc tgcaatgatg gatatgtcca tgaagattgc ggatagtgtc
     8101 gttaggcccg agcaacatcg gataatgagt caagtaatat tgttgatggt cgaatttaac
     8161 gatggcacct acatcataaa aataaaattt gggacttccg tcagtaagcc taggatcatt
     8221 tttttctaaa taacggaaaa aagcgcgact gtcatggttc cctttgatca agtggattgt
     8281 tccttgcagt tgagtgacca gttccaaaat ttctgcattt gctttttcat attgcggatg
     8341 catagcaagg tcgcctagat gataaacatg gtcggtttct tttattactg cattccagct
     8401 agtgatcaac tgttggttca tttcatccac atttgcaaag agccgcggag caaagtcgtt
     8461 ttttcctaat aagcgttcat ggaaaaagtg catatcactg ataaagtaat tcatgtatct
     8521 tttgcctccc ttttttctta gagtaaacaa aatcacttat ctgagcaact cataacatct
     8581 aaaaagaaaa ggttgtaaat gagacgtgca gctttaagcg ataagaagca attttgaaaa
     8641 atagtttttc acaatttata aaattattcc ttattgccga aaggctggcc ctttttatga
     8701 gtatgccaat tttttatatc gaatgctcaa aagatgagtg attttttggt tgactatcat
     8761 gtttgtgtac tgaataggtc cagtagaaca gtatttttac gacttgataa ttaagggatg
     8821 aaattttcag aaatatgacg tataatgtaa aatactgaaa agttgcgacc ttcaactcgt
     8881 agatgtttca gaatctaatt gaaatgatgg tgatatcatg acagacaaca gcaaaacacg
     8941 cgttgtcgta gggatgagcg gcggtgtcga ctcatctgta acagcacttt tgttaaagga
     9001 acaaggatac gacgtgatcg gaatattcat gaaaaattgg gatgacacgg acgaaaacgg
     9061 tgtatgcacg gccacggaag attataagga tgtagcgaaa gtagctgctc aaatcgggat
     9121 tccttattac tctgtgaatt ttgaaaaaga atattgggat cgtgtatttg aatatttcct
     9181 agccgaatac cgcgcaggac gtacacctaa cccagacgtg atgtgcaaca aagaaatcaa
     9241 attcaaagca ttcttggatt atgcaatgga tcttggcgcc gattatgtag ctactggaca
     9301 ttatgcgcaa gtcactcgcg atgaaaacgg cgtggtccac atgcttcgtg gagtagacaa
     9361 taataaagat caaacttact tccttagcca attatcacaa gaacagcttt caaaaacgat
     9421 gttccctcta ggcggcatgg aaaaatcaga agtacgggca attgctgaac gcgcaggcct
     9481 tgcgactgct aagaaaaaag attcaacggg aatctgcttt attggtgaaa agaacttcaa
     9541 acaatttttg agcaactatc tgccagcaaa aaaaggaaat atggtcactc ttgatggtga
     9601 agtcaaagga caacatgctg gcttgatgta ttatacgatt ggtcaacgtc aaggactagg
     9661 gatcggtggc ggaggagatt cgcaagaacc ctggtttgtt gtaggaaaag atctagcgac
     9721 aaacacatta tatgtggggc aagggttcca tcatcctgca ttgtatgcca caagcttgga
     9781 tgcaagtgaa atccacttta cgacgaatga accaatgcca aaagaattca agtgtacagc
     9841 gaaattccgt tatcgtcagc aagacgttcc tgtgacagtt cgcttattgg atgataatcg
     9901 tgcagaagtc gtattcgacg aacctgtacg tgcaatcact cctggacaag cagttgtatt
     9961 ttatgatgga atggaatgtc tgggtggtgg tttgatcgac cacgcatatc aagaaacaaa
    10021 agttttacaa tacgtttaag cgatattaaa tgaatcaaaa cagctatggc taacaaaaga
    10081 aacacctttt cttttggata gcatagctgt ttttttgcaa taaaattaat ttttattcat
    10141 tttatacttg aaatacttgt gtaaaaagtt cataatatcc aataatatga ataaagttgc
    10201 tttttgttaa gcaagagcag ttgcaaaata gaagggaatc ttttgcaagt gatttgttca
    10261 attttataag tgagggtgat ggaaatggaa aagaaatcga cgggtattag caaatgggga
    10321 ctggttgctc tggttgtcag ttcgtcaatc ggaagcggtg tgtttgggat cacaagtgat
    10381 ctggctagtt ctgcagctcc agggccagcg atcctttcat ggataatcgt tgggattggt
    10441 attttagctt tggtattatc gctgaatcat ttaggagaaa agcgtccaga tctagatggt
    10501 ggtattttcg gttacgcgga agcttcattt ggtaaattag gtggcttcat cagtggttgg
    10561 ggttactggt tgtctgcgtg gctgggaaat gttgcttttg caacgatgct gatgagcgcc
    10621 atgggagaat ttttcccgat attcaaaggt ggacaaaatg ttccttctat tttatttgca
    10681 agtattttta tttggggtct gactttatta gtaaacaatg gagttgaagg agcgagcgtc
    10741 atcaatacaa tcgtgacgat ctgtaaatta gtgccattat tcctattttt aatatttgta
    10801 tttatcgcat ttaaagtgaa tatattcact gctgattttt ggggtaacgt atctgataat
    10861 ctagtgaatg gaacagggca gcaaggaacg atctggttgc agattaaagg ttgtttgatg
    10921 gttatgatgt gggtctttgt agggatcgaa ggcgcaagtg ttttagccaa ccgcgcgaag
    10981 aaacgttcag aagcccagca agcatcgatc attggtctgc tttgtttatt gtttatctat
    11041 atccttgctt cgatcttgcc atacggcgtc ttatctcaag aagagttagc aactatttca
    11101 caacctgcta tggcaaatat tttaaaagga atcgtgggaa attggggagc agcgctgatc
    11161 aatatcggct tgattatttc gatcattggt tcttggttgt cttggacgat gctcccagca
    11221 gaaacaacga tgttgatggc tcgagacggt ctgttgccga aaggttgggg aaaaacgaat
    11281 aaaaaaaatg ccccaactta ttcgttagtt gttactgcaa tcttgactaa tctattctta
    11341 ttgactttct tagttactga ttatgcctat caatttgcct attctttatg tacagcggca
    11401 attttgattt gttatctact tgtcgggatc tatcaagtcc agttttcttt aaaagaagga
    11461 atcaaaaaac aagtagtgat cggtgggatt gctgtagttt ttgaattgat gggcatcatt
    11521 ttagcaggat tttcttatgt ccttttatgt agtattgcct atcttcctgg tttttgcttc
    11581 tactggatcg cttgtcgtga aaccaaacat caaattacgg gaaaagaaaa agtaatgatt
    11641 gggctgattt gtgtggccgc actgctttca atcgggttgc ttgctgtagg ctggatcaag
    11701 atataagggg gaaagaaaca tgaaaatcgc aaatttcggt gtagaagaat ggctaaataa
    11761 atgggaaaag aaagcggtat atgatattgc acaaagctcg atcgaagcat tgacattaga
    11821 cgaactcgtt ggcttagatg ggactagcgt aagtaaattt ttcgaaaaac gcaaaaacga
    11881 accattggac tatggctgga tcgaaggatc agatgttttc aaacaagaag tcgcttctct
    11941 ttatcaaacc gtcgatccgg aaaacatctt acaaacgaat ggagcgactg gtgctaatct
    12001 tttagctcta tacgcgttag tggaagcagg agaccatgtt gtttcgatgc ttcctactta
    12061 tcagcaatta tatgacatcc ccaaatcttt aggtgccgct gttgactttg ttcatttgaa
    12121 ggaagaagaa gattggcagt ttgatttaga acagctagaa gccttagtca aacctgaaac
    12181 aaaaatcatc tgtttgaata gtgcaaacaa tcctacaggc acattgctag atcggaaaac
    12241 tttagaaaaa atcgcagaaa ttgctcgtac agtagatgca tatgtattga tagatgaagt
    12301 atatgcgcct ttaacggata aaggtgaatt cttgtcgatc gtagatgtct atgaaaaagg
    12361 tatagcaacc aattccctat ccaaaaccta ctccattcca ggtattcgta ttggctggac
    12421 agctactgga cctgagttgg cagaagtttt tcgaaagtat cgagactaca cgatgatttg
    12481 cggcggagtc ctgtcagatg atcttgctgt acatgcattg aagaataaag aaaaaatatt
    12541 ggcgcgaaac aaaaagatca ttacagagaa ccttgtgatt ttaaaacaat gggtagccaa
    12601 tgaaccgaaa gttgaacttg tcgctcccaa ttacgtctct acttctttca ttaaattagc
    12661 catcgaagaa gatgaccaga cattttgtat caatttatta gaagaaacag gagtactatt
    12721 agtaccagga agtgcctttg atttaccgaa gcatgcccga ctaggttact gttgtaaaaa
    12781 agaaaccttg gaaaagggat tattcctctt atctgagttc ttgaaaaaac aggcctaaac
    12841 aaaaacactg caaggacagt ctgtgacaac tgttcaagca gtgtttttca tttacgctta
    12901 ttgtctatga gaaggagagt gccctgaagc tatggagact cctgaagctt tttcttctgc
    12961 agtttcttgc tgatggatct cttgtgtatt gtgtcgtaca agcaagaagt tgaccaaaac
    13021 aagaagagaa gtcgaaagaa agacgccacg ataaccaaat gcactggaaa cactggagcc
    13081 gatcataggc cctactacgt taccagttgc ttggaaagat tggttataac tgaagatccg
    13141 tccagcagct tgatgaggcg aatattttgt gatcaatgct tggacagcag ggagcagaca
    13201 agcatcagag ataccaatca aaaaacgtaa ggcagctaat tgccaaacat tcgtgacgaa
    13261 tgccattggg atataaacca gaatcgcaaa acccaaacca atcgcaagta ttctttcact
    13321 cccaatcttg tcacctaagc gaccaaatct tggagcggct atcaaagtgg caatcccagg
    13381 tatcgaagca atgattccgc tgatcaacgt aacattccca tgtccatgca gcaattggcg
    13441 aatgtacaga ctgatgattg gactaatgga attgttggat gcttggatga tcatcgttgt
    13501 gacgaacata ccgatgacga cgtgtggata tttcaagtct ttgaaaatct gtttggcaga
    13561 aaccatgttt tcttttttca ctgggacaaa tttttcatgg acgaaaaaca gactcaacaa
    13621 gaagacgaaa aataagatga tccctgtaat gaaaaaggta gggcgatagc caaacgctga
    13681 agcagagatc ccgccaagaa gcggtccaag taatgttcct gtaacagaac cagttgctaa
    13741 ggttccaaga acttgaccac ttttttcttt tggcgtccca gttgcgacaa gggcagtggc
    13801 attactgata taaccagaaa aaatcccttg aagcagacgc aatgcgacta attgatacac
    13861 actagtcacg caacccatca aagaaatgac gattgccatt cctaatgaag cacgcaacag
    13921 catcaatttt cttccttttt ggtcggctaa ttttccccac caaggagaga taagcgtagt
    13981 caccaagaaa gtagatgaaa aagtcaatcc gctccaaaag ttcaattgtg acgtactata
    14041 attacctaac gtatctatgt aaagtgacat aaaaggcatg actaaactaa atccgatacc
    14101 agccataaat gttccaaacc ataagacaaa caagttttgt tcccaagttt ctcttttcct
    14161 aaataatttt tcctttattc ttgcagccaa ttagactcct tctttctgaa aattttcatc
    14221 tacagctctt tattataaac tacaatatgt agtttatcaa tgaaagtctc ttttttctct
    14281 ttctttttcg tggtaaactg aaagagtgaa ggatttattt tatgagagga aacatggaaa
    14341 tgaaaaaaag aaatctgtct caagagaaaa tcatcgactg ctttcgagaa ctagcagaag
    14401 agatggatgt tcagcaaata acctttcagc atttagccaa acgcttggat atcaaggctc
    14461 cctcgctgta taaccatttc aaaaatattc gtgatgtcaa aacagcgcta acagcgaaac
    14521 ttctgcagga acttaatgac cagctgcgac gggctcttgt gggaaaaagt ggtcaggaag
    14581 cactgcagat ctatgcagaa acttatcgat cctttgcttt ttcaaatcaa gcagtgtatg
    14641 agttactgat cagtgtaccg cataccaatg aagctgtttt attagatgga atccatgaaa
    14701 cgaatcagat cattttgcag atatttgagg cttttcaatt aacgaaagaa gaaaaagttc
    14761 atcgaagcag ggaacttcgt agtatgatcc acggttatct ttccttacgt tttttaggat
    14821 actttacaaa agaaccaaca atcgatccag aagacagcta tttttggatg atcaataact
    14881 ttatcgctac tttgccttaa acaatcagat tcatttgtaa caattttaag atgttcatta
    14941 aatgaccctt ttataagaga aaattcttgc aactttcttg aaaagtgact aagatgagtc
    15001 tagaaaagct gaaagaagga gcacgagtat gtatcaagta attaccatgt tcggggacaa
    15061 tgagccttgg tggttttttg aagactggga agaagatatt gaagaagaag aaacattcga
    15121 gtctttcgaa gaagcacgac aagcgtacga aaaacaatgg aacgaaatcc atcaaaatta
    15181 tgaatatatc aatgcaaaaa gtaactttct cagcgccttt tggaatgacg gagatgagcg
    15241 ctggtgtgaa gagtgtgacg atgatttaca gcaatacaag ggacttgcgt tgttgaaaaa
    15301 tcatcagccc atcacagtag aaagcagaaa ggaattttat gaaacaacta attctagcgg
    15361 aaaaaccaag cgttgcgaaa gacctaagca aggtgcttgg tgctaatcaa aagcacaaaa
    15421 attattatga aggacccaag gtgatcgtta cttgggccct tggtcattta ttaggattga
    15481 aaatgccgga agatctgaat aaggaatggc agagctggca aatggacacg ttgccaatga
    15541 tccctaaaaa actaggaatc aaaccacttc ctaaaacagg acatcaatta aaagcaatca
    15601 agcagctggc tcagcgaaaa gatgtctcag aagcagtcat tgcgacagat gccggaagag
    15661 aaggggaact tgttgctcgc tggatcttag agtatgtgca tttcaataaa ccagtgaagc
    15721 ggttatggat ctcttctcaa acagataaag caatcaaaac tggattcaag caactaagac
    15781 ctgcgaaaga atatgatgca ttgtatgaat ctgctcttgc ccgggcaaaa gcggactggc
    15841 tggtaggatt gaatgtgacc agagccttaa ctgtgaagta cgcggataat ttatcagcag
    15901 gccgtgtgca gacaccgaca ctagcattag tgagagacca agaaaagaaa atcgagcagt
    15961 tccgtccaca aacgtatttc acgatcacgt tgcaagctgg aaaagaacaa gccaaaatgc
    16021 ttcaaaaaaa tcaatttgct ttaaaaacac aagaagaagc acaaaaactt gttcaattga
    16081 tcagtacaag caaaggaact gtcacagaag tccaagaaaa attaaaaacg gaatctgcgc
    16141 cattgcctta tgatttaaca gagatccaaa gagaagccaa tcaacgctat ggctattctg
    16201 caaagaaaac attaagtctt gtacaaagtt tgtatgagac ccataagatc gttacttatc
    16261 cgcgtacaga cagcaaatat ctgacaaatg acatgaaaag tacgatgaaa gaacgattgc
    16321 aagcagtcag cgactttgct cctgaggtca agcagtattt gaaaaacgga gccatcgtcc
    16381 aacagacaaa agtattccaa gacagtaaag tgaccgatca ccatgcactt ttgccaactg
    16441 aaaacagagc acgttatgaa aaattaagta atgaagagcg aaaaatctat caaatgattg
    16501 tctctcgttt tttaggactg tttgctcaac cccataaagt cagccaaaca aaagttacgg
    16561 ttgaatttgg taaagaacga ttcatttttc ggcaaaatcg tgtcgtccaa gcaggatgga
    16621 aaggcgaaac tgaaactgag acggaaacag tcaaatggga aaaaggaatg agaatcaatc
    16681 ccgatttcgc catcaaaaaa gaactatctg caccgcctaa accattgtca gaagcaagct
    16741 tgcttggtca aatggaaaaa tacagtctgg gaaccccagc tacgcgtgca gagattatcg
    16801 agaaactaat caaatctgaa ctgatggaac gtacccctca aggattgcaa gtatctccta
    16861 aaggtaagca attattagta ttggtaaatc cctctttagt aacaccagat ttgacagaaa
    16921 gctgggaaaa agaccttgaa gctattgctg caggaaagaa acaagcagga accttcttga
    16981 atggaatcga aaaagaaaca aaacgcttgg tgaatgagat caaatcaagc aaacaagaat
    17041 atcaagattt ctcgattacc caaaagaaat gcccagaatg tggggccaat ctgcgcgaga
    17101 aaaacacacg tgacggcaaa atctatgtct gcaccaattc agattgcaac taccgcagaa
    17161 gaaaagatcc aaaagtctct aatcatcgat gcccgcaatg tcaccggaaa atggaaatca
    17221 tcgaaggtaa aaacggtgct tatttccgtt gtaaatacga tggaacgaca gaaaaattgc
    17281 ttgataaaaa agagcagaag aagaaaatga ccaaacatga agaacgacgc ttgctgaaaa
    17341 aatatgcaca agcagaagaa ccagaagaaa gcccattagc agcagcacta aaagcagcaa
    17401 tgaagaagta ataagatatg aaagaggttg tgatagaagt ggtcagcttc aagaaataag
    17461 aaggaattta cgaaaattgc ttctcaaatt tttgtgaaat ttcggcttat ttccgaagaa
    17521 gctacttctg gaacaccatt tattcggaaa aaaggactgt gacaagactt ttgtcacagt
    17581 cctttttcat ttaaaaaaat gtttacttca tttgacgtat attattggtg aggcttcaat
    17641 tcatttggct tcactttttc tgtttctctt atgatataaa caggacgctg tttcgtttct
    17701 aagaagattt tcccaatata tttcccgatg attccaagac ataacaattg gattccacca
    17761 atgaacagga agatcgagac catggaaggc catcctgatg taggatcacc aaacaacaat
    17821 gcccgcaaaa taatgaacaa aattgcaata ccagaaccga cacaagacaa agcgccgata
    17881 aatgaagcaa tcgttaacgg tgcatccgag aagttcacga taccatcaat cgagtagttg
    17941 aataatttcc agaaggacca agatgtttcg ccagccacac gttcgcggtt ttcataagaa
    18001 atatattctg ttttaaatcc gacccagcta aataatcctt ttgaaaatcg gttgtattct
    18061 gttaattcta ggacggcatc caccatttga cgagtcatca agcggaaatc acgagcgcca
    18121 tcgaccattt ctgtatcgct gattttattg atcaactggt agaatttttt cgcaaagaaa
    18181 ctgcgtatcg caggctcgcc ttcacgagtc gaacgccggg tgccgacaca atcgatatca
    18241 gaagtagtga tccggttgat catctcagga agcagttcgg gcggatcttg cagatcaaca
    18301 tccatcacgg tcactaaatc tcctgtagaa gcttgcaatc cagcgtacag agccgcttct
    18361 ttcccaaaat ttctggaaaa tgagacaaag cggacataag gataagctga ggctagcttc
    18421 ttgattgctg ctaacgtacc gtcttttgat ccgtcgtcaa taaacaaata ttcgaactca
    18481 tgggcacctt tgaatttttc aacctcatca aaaaaaagag gaacagtttt ttcttcatta
    18541 aaacatggga caacaattga tactttcatc gtttctatcc tttcaatcgt atgtttatat
    18601 atggtttaca ttcaaaattt aataaacctt aaataacacc tttaaaattt gattttacgt
    18661 aaaagaacag gtattctttt tgtaaactaa cgtatttagt ttaccatgtt tcctcggttt
    18721 atcaaacttt taagaacaat ttttattagt tggcaagtag ttttggatag agaaaaagga
    18781 ggaagttcca gtctattgac taggagcaaa caaaatgaaa atacacacac ctatcggctt
    18841 tttatggtta gatgcagatg aatccggatt gactgctgta tcttttcagc caatttcaga
    18901 aagcgaatca gcgaatcagc gaattttaac gcgcacacaa gaacagtttg aagaatattt
    18961 tgcgggaaaa agaaaagaat ttgatgttcc tttatctata aagagaggta cgccttttca
    19021 gcaaaatgtc tggaaagctt tgtcgaccat tccttatgga gaaatccgaa cgtataaaga
    19081 agtagccgtt gctgttgata gtccgaaagc tgtgcgagcg attgggcagg caaatcgaac
    19141 caatccattg ccaatcgtta ttccttgtca tcgagtgatc gggcaaaatg gaaaactgac
    19201 aggatatatg ggaaacgcaa tagatggggt tgaaatcaaa cgccaattgt tgttgttaga
    19261 aggatatctg caaaattaaa aacagttgtg attcggacat tgttccatgc gagaatcaca
    19321 actgtttttt catgttcatt ctaaactttg atcagccaaa taaatagtaa agccatcact
    19381 gtttggagaa gcccgacagc taatccataa gataagaagc gtgtaccttc tttcatgaat
    19441 tttgcaaagt ctaaacgcag accaattgcc gctaaagcag tgatctcaaa ccagctgctg
    19501 ataaaatgtg ccgattggtc aataactaca ggtaaagaaa acaagctgtt gaccaaacaa
    19561 aagatcacaa accctaatac ataccaagga agcggtaatt ttcgtttttt ctgcgtatca
    19621 gttggcgttt caaacagagc tggttgtttc ttgtgcatga atttttcaaa cagatagaca
    19681 acaacaacga gcatcataat acgtagaatc ttaaatagca tggcgaattc gacaacagaa
    19741 ttgtcaagta agcttgcccc agcgactact tgaccaacag attggagtgt accacccaaa
    19801 agtgcacttt tttcaatgag atttccacca aacaactgta atccaagaaa agggagagtc
    19861 aacatcatca cagtacccag tagattgact agtgtgatga tctgtccttt ttcttcctct
    19921 ttcgcatgga tggaaggggc gattgaagca atagcagaag aaccacaaac agcgtttcct
    19981 ccagccatca tcaaagaaga agtatcgctg aattgcagtt ttttaccaat caagtaagca
    20041 ccgatgatag tgactgacat ttgcagtaac acaaaaacaa ttccttttac accaatttga
    20101 gcaatcgttt gagctgtgac agttgcacct agtaaaaaaa cagagaattc taatagtttg
    20161 ctttcagcaa attttgtgcc gattgctaga acaggctgtt taaaaaaagt atttcctaat
    20221 aaaataccca ataaaatagc aatagtcgct ccacctaact gtggcagata aatagcaaga
    20281 agcctgctga aggcagcgat ggcaaaagaa agcagtaaac cgggtaagat ttcgcggacc
    20341 gctgaatcct ttacagattt tattggatgt gacaatgatt tcatttgatc ggttcctttc
    20401 gtcaataaat actaaaagca tactcgaaca tagtagcact aaaccagtat tttgacaaaa
    20461 gaacaagagg tcgtgacaaa agtcttgtac gacctcttgt ttcgaataaa cggtgttcca
    20521 gaagtagctt ctacggaaat aagccgaaat ttcacaaaaa tttgagaagc aattttcgta
    20581 aattccttct tatttcttga agctgaccac ttcttttacg acctcttggt aaacggtgtt
    20641 caaaagcttg catctgcggt aataagccca accagtacaa aaacatgaac agctgttttt
    20701 gtttggccgt tcttattact tgatgcagaa cagctttttc acaacctatt gaatcgatta
    20761 ttaagcgatt tttttagaaa caaattttcc atgtttgcta tgttctttaa ttaagaaacg
    20821 tacgtaatga gcaagaacgt agaagacaac tacacttgca aacagacatt ccgcaacttt
    20881 taagaaatcc aatacgctac tatagatacc taaactgttg aagtaatgaa cagtagtaaa
    20941 tatagctgtt gcagagataa caagcgggaa tgtaaaggct gcatagcttg gataaaaacg
    21001 aagcttgaac aaacgtggaa gcatagacag cacaacgaaa tacaatactt gagataaagc
    21061 gaacaatgct acgacaagat aaaaattagg ttcagcaaag tttttaagat aacctgttag
    21121 gcaaagagaa ccaggtgctg caacgatcgt aatcagcgga cgtgtcggat gagccatatt
    21181 tcttacgaaa aagacacgtt tgatgatgat cggcaataag aacgcatagc agatcaatga
    21241 aatccaaaag aaaatttttc caataagtgg gaagaagttc ccggcagtta cagtgatgac
    21301 cccaaatcca acgtaaatga taaaccagct tggataaatt gcttcaattg aaagatcagc
    21361 tttgataaca tggtgataat tgaaataaaa gacaaggatc acttggaaga taacagcgca
    21421 cagccaaatg aatttgacaa ttggtgcaat actttcatat gaaacaaaat aagtacaaat
    21481 aaccatgagt gacatcgtaa aagttggtga aacggaggcg atgattggat catgcaacgt
    21541 ttgtttcgtg tgttcgaata agataaacaa tttaacaaaa atgaatatca taagaatcat
    21601 agagataccg ccagttagat tgcctaaagc aacatggtga tagtctttaa acagatttcc
    21661 aagggaagct aacccaagga tcaacccgca gatcgggatc ggaataattt tcaaaaagtt
    21721 cttcatatat aatattctcc tttttattta atagatttta gtaccaagat gaacgaatac
    21781 attgtaaaat gaataggaat gtatgattac gagcaagcag acagctgatt gtcttcatct
    21841 aagttactag ttggatcagc aactgttttg ttgtacattt ctattataga tggttttttg
    21901 tatatttaaa tcaaatagtt tttatagtaa ttatcataaa aagttatgga agtggtgcca
    21961 tgtttaagtt attaacgact tttcgagcag tatatgaaac aagaaatttt tccagagcag
    22021 cagaagtact gtttttatct caaccagcag tctcgaatca aatcaaacag ttggagcggg
    22081 aattgaatat cgatcttttt caacgtaacg gaagaaaaga gatgcttcca actaagcaag
    22141 ccgacttatt atatgaacgg acactggttt tgttagaaga atgggaagaa actcagcaaa
    22201 aattgctcaa tgaacaaaat gaagaagaag tatgtcggat cgttgcttcc cacacctttg
    22261 ctgtctatct tttgcctcag ttgatgaaac atctgatcaa aaggtttcct aaagtgcatt
    22321 ttgagatcga aatcacgaat tctcatgaat cattagaaca agtagcgaaa catgaatccg
    22381 attttggttt tatcgaaaag ccattagaga cttccggcgt acaaagatac tctttgatgg
    22441 aagaccagct agtcatcgct ggggacccaa aaagcaaatt gtggcttgta agagaagcaa
    22501 actctggtgt ttttcattac acgcagcgtt attttgaaga gatgaatatc caagataaga
    22561 agatgatcgt gaaaagtaac gatgtaattg ttgcgttgct gaaggaagga atcggtcgct
    22621 cgattttgtc taagcgctct gttccagaaa atgtgccaat gactccgttg aatttccatc
    22681 gatattttta tttcatccaa cgaaccaatc tggtttctga tcagctgcta gagattgccg
    22741 aagagatcct tcgatacaat gaaagcacag aaacttctca cagcgaggag aatctcagct
    22801 ggtagataat tgcatgtatc aaaaaaagtt ctatgataca ctaaagataa gcagtaggct
    22861 tttgtactgc atttgctcaa gcaactgcac aaacggaaag ttaatttttc ccaaatgtct
    22921 atggaaagac tttccattat ctaactggac cgctataata atcagcagta tggtttttaa
    22981 gaaaagggat gaaacatgga aaaaaaatta aaagcttcga acgataatcg tattgattat
    23041 ggcgtgattt taccagtctt tctgttatgt ttgattggtc tgctctcatt atatgtagca
    23101 cttagccatg atccgaacaa tccagcagtc ttgaaaggcg tagggatgca agttgtctgg
    23161 tatttagttg gagcggcagc aatcgttgtc atcatgcatt tgaattccaa atggatctgg
    23221 aaactgactc cttaccttta tggtttgggg ttagtggtaa tgggactctt gctcaaattc
    23281 tatgatcaga atttagctgc ttcaacaggg tctaaaaact ggtttcgatt cggtgcgttt
    23341 actttccagc cagcagagtt gatgaagatt gcgtacatct tgatgatggc actgatcgta
    23401 actaaacata atacgcaagt aaaagaacgg acgatgaaat cggacttttg gctgattggg
    23461 aagctcttga tcgtgacaat accggtttta gcattgatca tggcccaaga tgactttgga
    23521 acgatgcttg tctttcttgc gatctttggc gggattttcc tgatgtctgg aatctcttgg
    23581 cgcatcatcg cacctgtagt aatcttggca gtagtcgttg gagcaggaac gatcttcttg
    23641 gttacgactg aaggcggaag agacttgctt tataaagttg gattcaaatc ttatcagttt
    23701 gcacgtattg attcatggct ggaccctttc catgatacgt caggaatgag ttatcagccg
    23761 gcccaaggac ttttggcaat tggtaccggt ggcttgtttg gtaaaggatt caacgtaagc
    23821 aatatctatg tgcctgttcg tgagtccgat atgattttta ccgttatcgg tgaaaacttc
    23881 ggctttatcg gtggtgcatt cgtcattttc ttgtatttta ttttaatcta tcgtatgatt
    23941 cgggtgtgtt tcgatacgaa taatgaattt tacgcctata tcgcaagcgg tttgatcatg
    24001 atgctgctgt tccatgtctt tgagaatatt ggagcaaata tcggattact tcctttaaca
    24061 gggatcccat tgcctttcat tagtcaggga ggatcctcga ttttagggaa catgatcggt
    24121 atcgggttga tattatcgat gagataccaa aatgaagcac ctgcaagatc ttcaaggagg
    24181 taagaaaatt gtacaccttt tactggtacc cgaaatgttc aacatgcaaa aaagccaaag
    24241 cgtggttaga ccagcatggc gttagttatc aaaccgttga tatgatcaaa gaagtaccga
    24301 aggcctcaac gattgagact tggctagaaa cgagtcaagt accaatccgt cgcctgttca
    24361 acacaagcgg gatgaaatat cgggaacttg gactgaaaga tcaagtaggc gagtttacgg
    24421 cttcaaaagc gagccaagtc ttatcgacag atggtatgct gatcaagcga ccactgatct
    24481 tacgagagga ccagcttgtt gcaattggat tcaatgaaaa aatttatgaa ggagaactga
    24541 tataaaatgg caggcaagca tttgaagaaa aaggacaacc tttggatctt atttaatgga
    24601 aaagaatact gtgttggttt gacaaatgaa gcgcaagaag aacttggaga catcacgttt
    24661 gccaatctgc caaaagcagg acaatcgcta aaaaaagatg aacctctgat cgaagttgaa
    24721 gcggaaaaag cggtcaatga atttgccagc ccgctaacgg gtacagtttc ttctgttaat
    24781 gataaaatcg gtgaagatat caatatcttg aatgattcag atgaaatgaa tgcgtggatc
    24841 ttaagtttca aagatgttga tccaaaagaa tttgacgaat tataaaatca gaaaatcact
    24901 tgaaaaaagt tgacactgat tcttccagtt gctataatca taagcaatcc tatatgaaac
    24961 gagaaagctt tgaaaagaag agtacatgtc acggacgttt gaagagagcc ctgtttgctg
    25021 aaaatgggta acgaaaatga gatggaagat ggtcttagag cagagtaagc gagcgtaagc
    25081 aaacttacta cgggagtgcc cgttacagcg cgacagtata cggaaagaag ctaagtccaa
    25141 gtactggaag aggctgttat tgcgaagtaa cggtaaatca aggtggtaac acggaagttc
    25201 aagctttcgt ccttttgctt aaggcaagag ggcgaaggct tttttgtttg aaaaatcata
    25261 agagaaagat gtgaatggca tgtcattaat ccaactaacg aatgtcaaaa agacattcaa
    25321 tgggaaaaac ggaaacatcc aagccgtcaa tgacgtttca ctaaacgttg aaaaagggga
    25381 tatttatgga atcgtcggct attctggcgc aggaaaaagt acattagtcc gtctcctgaa
    25441 tggacttgag cttcccacga gcggcgaagt gatcgtaaac gatcaagata ttacaaaatt
    25501 aaaaaacaaa gaattacgta cattccgaaa gaaaatcggt atgatcttcc agcatttcaa
    25561 cctgttatgg tcaagaactg tacttgaaaa tatccagctg ccgctggaat tagctggcgt
    25621 accaaagagc aaacgtaaag aacgggcaga agaactgttg cgtttagtcg ggttagaagg
    25681 acgcggacaa gcatatcctt cacaactttc cggcggacag aaacaacgcg tcggtatcgc
    25741 acgagcattg gcaaatgatc ctgagatcct gctttgtgat gaggctacta gcgcattgga
    25801 cccgcaaaca acagaagaag tattagactt attgttagcg atcaataaga aattgaattt
    25861 gaccatcgtc ttgatcacac atgaaatgaa tgtgatccgc aaaatctgca acaaagtcgc
    25921 tgtgatggag ttggggaaag tcgtagaaga aggagacgta ttgactgtct tcagacaacc
    25981 gaaaaaagaa gtaaccaaac gctttgtaca acaagacatc gaaccagaag ctgattcgac
    26041 agaactatta gctgaactca tcaaagaaaa tccaagcggc cgtttggcaa ctttgacctt
    26101 tagcgaaaga aatgccaacg agccagtcat ttcccaagcg attcgacgct ataacatcga
    26161 tgtcaacgtt gtgtatggaa agatcaaaca agtgaaagaa ggttcctttg gttcattgac
    26221 tgtcttgatg actggtgaaa ccaaagaatt agatcaagca gaagtgttca tcaaagaaca
    26281 aggagtagga attgaggtga tccatcgtgg ataaaagctt ttcagaaaca tatctagatt
    26341 ttaaacaaat caacccggaa acgatgaatc aggctatcct tgatacacta tatatgacat
    26401 taatctcaat ggtcttagtg acgatcatcg gattagtttt gggattgatc ctttactcta
    26461 ttggacgcaa aaacaaaccg tatgctcgaa tcatttatgg aatcgtatcg atcatcagta
    26521 atattttccg gtcaacgcca tttatgatcc tgatggtttt gatcattcca tttactaaag
    26581 caatcgtagg cactatgcta ggtgcgcaag cagccattcc agctcttgtt ttatccgcag
    26641 caccatttta tgcccgtcta gtagagattg cttttcgtga agtcagccct ggtgtactgg
    26701 aagcagcaga tgcaatggga gcaagttact gggaaatcat ctggaaggtc ttgatacctg
    26761 aaagtattcc cgcattgatt tctggattaa cagttacaac gatctcgatg atcggattta
    26821 ctgcgatggc cggcgcgatc ggcgcaggtg gacttggagg tcttgcttgg caggaaggct
    26881 accagcgtgg taatctaaca gtgacattcg ttgcgacttt aattatttta ctaatcgtat
    26941 ttatcgttca aggaatcggt gatttcttaa ctaagaaaac agacaaaaga taataggata
    27001 tagggggatg taggatatga aaaagaaaat ttttggattt gcagcagcgc ttttgctgac
    27061 tgtaggatta gcagcatgcg gtaacaacag cgacagcaaa gattcagcaa ataaagcaga
    27121 cgacacgaca ttgaaagtcg gcgcttcacc gacaccgcac gcagagattt tggaacatgt
    27181 gaaaccatta ttgaaagatg aaggaatcga tcttgaaatc gtcaaattcg atgactatgt
    27241 attaccgaac caatctttgg aagaaggcga cattgatgcc aattacttcc agcatattcc
    27301 ttatttgaac aaagaaatca aagaaaaagg atatgacttt gtcaatgccg gtgctgtcca
    27361 catcgaacca atgggcttgt actctaaaaa agtcaaagat gtttccgaat taaaagatgg
    27421 tgcaacaatc attacttcaa attctgaatc agactgggga cgcatcatca caattctaca
    27481 agatgctggc ttagtcaaag tcaaagatgg agtagatctg gaaacagcaa cattcgatga
    27541 tattgaagaa aaccctaaga acttgaagtt caaccatacg atcgacccat cacttttagc
    27601 ttctacgtac caaaatgatg aaggtgacct agttgcaatc aacgcaaact tcgcttacgg
    27661 cgcagggttg aatccattag aagatgccgt attgcttgaa aaggacaact ctccttacgt
    27721 gaatattatt gcgactcgta aaggtgatga agacagtgac aaaatcaaaa aactgattga
    27781 agtgcttcac cgcaaagaag tccaagaatg gatcacagac aaatggggcg gctctgttaa
    27841 accagtaaag gctgatgcaa aataaggtat ggaacaaaaa agatgagaaa taagtctgta
    27901 atggcttatt tctcatcttt tttataccta ttctaattta gaaatcaaaa ttgtttaata
    27961 ataaataaaa gatatttgat tttagtaagg aaggtcattg cgcttcattc tcaattagtc
    28021 taaaatgagt gagaacgaaa gagaatttgg gggtataatg catgtctgtc ttagaaataa
    28081 aaaatctaca tgtgtcgatc gaggaaaaag aaatccttaa aggcgtaaac ctaacaatga
    28141 aaaccggaga aatccatgcc atcatgggac ctaacggcac aggaaaatct accttatctg
    28201 ccgctatcat gggcaatcca aactatgaag taacagaagg cgaaattttg tttgacggga
    28261 aaaatgtttt agacttggaa gtagatgaac gtgcgcgact tggcttattt ttagctatgc
    28321 aatatccaag tgagatacca ggtatcacga atgcggaatt catgcgtgca gcgatcaatg
    28381 cgaaacgtga tgaaaacgac aaaatttctg ttatggcatt tttgaaaaag ttagatgaaa
    28441 aaatggcttt actaaatatg ccagaagaaa tggctgaacg ttatctgaac gaaggttttt
    28501 ctggcggaga aaagaaacgg aatgagatcc tgcaattgtt gatgttagaa cctacatttg
    28561 caattttaga cgaaatcgat tcaggtctgg atatcgatgc tttgaaagtc gttgctaaag
    28621 gagtaaatga aatgcgcgga gacaatttcg gtgcattgat catcacccac tatcaacgat
    28681 tattgaacta tatcacacct gatgtcgttc acatcatgat ggaaggccga gtagtcatga
    28741 cagggaatgc tgacctagct aaacgtctgg aagcagaagg ctacgctggt atcagtaaag
    28801 aattaggaat cgactataaa gaagaagaag cgtaaggggg agcaagaatg aaagaaaaaa
    28861 actggctcga ttatcttgac gcggtaaatg atttttcttt aagtaaaggc gaacctgatt
    28921 ggatgagaac cttccgtcaa gacgcactag cgaaagcaga tgaactgcca ttgccgcata
    28981 tcgatcgggt gaaattccat cgctggtcgt tatttgatgt gaaagaaaca caaaccatca
    29041 gtgaaacagg cacgattccg gcatttgatg caatgaaaga caatcctgtg cttgtccaac
    29101 aaggttcatg gacgattttt gaacaactgc ctgtggaatt agcagaaaaa ggagtcattt
    29161 ttaccgactt gttcactgca atgatcgaat atccagaact agtccaagaa tattatatga
    29221 aaaaagcagt aaacatgaac gaagaccaat tgactgcact ccatgtagct tttatgaaca
    29281 gcggtatttt cctgtatgtg cctaaaaatg tcgtgatcga tgaaccactc gagtccttat
    29341 tcattcaaga tggcgcatcc gatgagcact tcttcaagca tgtgttgatc gtggcagatg
    29401 aacatagtga attttcttat ctggaacgtt tccagacaac caaagaacaa gtagcaaaat
    29461 catcaggtaa tatcatcgtg gaagtcatcg ctaaagctgg ttcaaaaatc aaatattcag
    29521 ccgtagatca attaggagaa aatattactt cttatatgaa tcgccgtggg cacattttac
    29581 gagatgcttc tgtcgactgg gcaattggtg tcatgaatga cggtcatgtg atcgctgact
    29641 ttgactcaga tttagcagga gaaggtgcac acgcagaagt caaaatcgtg gcaatcagct
    29701 cgggcagaca aatccaagga atcgatacac gagtaaccaa taaagcccct catacgatcg
    29761 ggcatatttt gcaacacgga gtgatccgag aaaaaggaac attgaccttt aatggtatcg
    29821 gccacatctt gaaaggggca aaaggtgcag atgcccaaca agaaagtcgt gtcttgatgc
    29881 tttctgataa agcacgtggt gatgcgaatc ctattctttt gatcgatgaa aacgaagtaa
    29941 ctgctggaca tgctgccagt gtaggacgag ttgatccaga agaaatgtac tatctgatga
    30001 gtagaggatt gcataaagaa gaagcagagc gcttagtgat tcgaggattc ctcggttctg
    30061 tcttaacagc aatccctgta gaacaagttc ggaaagaatt agtcgaagta atcgaaggga
    30121 agttgaatgg atgatcgatg ctaaaaagct acgcaatgat tttcctatct tatttcaaga
    30181 cgtcaatgat gaacctttag tttatctgga taatgcagcg acgacccaaa agccaaaaca
    30241 agtactccag gcattagcgt actattacga acacgataac gccaatgttc atcgcggtgt
    30301 ccatacgtta gcagaacgcg cgacccatga ttatgaacaa gcaagagaaa aagtacgggc
    30361 gttcatccat gcaaaagaaa cagcagaagt gctgtttact cgtggtacga cgacaagctt
    30421 gaattgggta gccagaacct tcggcgaccg ctatatcaaa gcaggagacg agatagtgct
    30481 ctcttacatg gaacatcatt ctaatgttat cccgtggcag cagttggcaa aacgaacagg
    30541 tgctgtcttg aaatatatcg aactaacaga agaaggcttc ctggatatgg aggatgcagc
    30601 gaaaaagatt acggacaaaa ccaaaatcgt ctccattgct catgtatcca atgtcttagg
    30661 tgtcttcaat cctgttcaag aattagctga acttgtccat gaaaacggcg gggtcatcgt
    30721 agtagatggt gctcaatctg ccccgcacat ggccattgat gtccaagcac tagactgtga
    30781 tttctttgct ttcagcggac acaaaatgtg cggaccaaca ggtattggtg ttttatatgg
    30841 taaacgaaaa tggttagaag aaatggaacc tgttgaattt ggtggcgaaa tgatcgattt
    30901 tgtcgaatta tacgacagta catggaaaga actaccttgg aaattcgaag cagggacacc
    30961 aaatatcgcc ggcgctatcg cattaggcca tgcaatcgat tatttgcaaa aactcggtat
    31021 ggacaatatc catcgatatg aagaagaact agccgcttat gtgttgccaa aattacaagc
    31081 aattgatgga ttgactgttt atggtccaca agacccgaat tttcggacag gagtcgttgc
    31141 attcaatttg gatgggttac atccccatga tgtcgcgaca gctttagaca tggaaggggt
    31201 agccgtcaga gcaggtcatc attgtgcgca accgctattg aagtaccttg aagtatcagc
    31261 gactgctcgc gcgagctttt atttctacaa cacaacgcaa gacgccgacc gtttagttga
    31321 agcaatcatg gcaacaaagg agtttttcca acatgggact atctaaatta gacaatttat
    31381 accgtcaagt gatcttggat cattcttccc atccgcatca tcgtggaagc ttgactgact
    31441 cgacaagcaa gatcgaattg aacaacccca catgtggaga tgtgatcgaa ttgcaagtcg
    31501 atgtaaaaga cggaatcatc aaaaatatcg cctttgacgg cagtggctgc tccatcagta
    31561 cggcaagtgc ctcgatgatg acagacgccg tcatcggaaa atcaatagaa gaagcagaac
    31621 atttaactgt agactttcta cagcttgtcc aaggaaaaga agtcaaagat cccgaccaat
    31681 taggcgatgc tgctatgctt ggtggtgtag ctaaatttcc cgctcggatc aaatgtgcga
    31741 cacttgcctg gaaagcacta ggaaaagcaa tggaaaacga tggtaccgca gctttccatc
    31801 attaccacaa ggaagaggag tgagaacatg ggcgtaccag aattagaaga atataaattc
    31861 gggtttcacg atgatgtcga accggttttc agtacaggag aaggcttgac agaagaagtg
    31921 atccgtgaga tgtcaagaat caaaggcgaa ccagaatgga tgcttgaatt ccgtctgaaa
    31981 tctctagaaa catttaacaa aatgccaatg caaacatggg gccccgacct ttcagacatc
    32041 gatttcgatg ccatcaaata ttaccaaaaa ccaagtgaca aacccgctcg tgactgggaa
    32101 gacgtaccag aaaaaatcaa agatacattt gaaaagattg gtataccaga agctgaacga
    32161 gcttatctag ccggtgcttc cgcacaatat gaatcagaag tcgtgtacca taatatgaaa
    32221 gatgaattcg aaaagttagg aatcgtcttt actgacactg actctgcttt gaaagaatac
    32281 cctgaattat tcaaagagta cttttcaaaa cttgtaccgc caaccgacaa caaattagca
    32341 gcgctgaatt cagccgtatg gtcaggtggg acctttattt acgtgccaaa aggcgtcaaa
    32401 gtcgatgttc cattacaaac gtacttccgg atcaatgcgg aaaacacggg gcaattcgaa
    32461 cgtacgctga tcattgttga cgaaggagca agcatccact atgtcgaagg ttgtacggca
    32521 cctacttatt caagtaacag cctgcatgcc gccatcgtag aaatctttac aagaaaagat
    32581 gcgtattgcc gttacacaac gatccaaaac tggtcagaca atgtgtacaa cttagtaacc
    32641 aaacgagcaa aagcatacga aggcgcaacc gttgaatgga tcgacggaaa cctaggtgca
    32701 aaaacaacga tgaaataccc aagtgtttac ttagatggaa aaggtgcacg aggcaccatg
    32761 ctctccatcg cctttgcagg agcaaaccaa atccaagata cgggtgcaaa aatgatccac
    32821 aatgcaccaa atacatctag ctctatcgtc tctaaatcaa tttcaaaaga cggcggagaa
    32881 gtaaactatc gaggacaagt aacctttgcc aaaaacagtg cgggttcgat ctctcatatc
    32941 gaatgtgaca cgatcatcat ggacgaatgg tcgaaatccg atacgatccc attcaatgag
    33001 atccacaaca gccaagtctc tttagaacac gaagccaaag tctcaaaaat ctcagaagaa
    33061 caactctact atctgatgag ccgaggcctg accgaatctg aagcaactga aatgatcgtc
    33121 atgggctttg ttgaaccatt caccaaagaa cttccaatgg aatatgcagt cgaactcaat
    33181 cgattgatca gttatgagat ggaaggcagt gttgggtaaa cctgttatag gagctagaac
    33241 ccttgatata taagggttct agcttttttg ttttgcctgt atactagaaa tgaccagatt
    33301 ttgaccagct cttttactga tgagccatca tatcagcaaa gtcttgacct gttttcttag
    33361 gtgcattatt tgtaatatgt gcatagatgt ctaatgtcac tttactattt tcatgcccta
    33421 atcgttgttg aactaccttg acagattctc ctgcttctaa taataaacta gcatgtgtat
    33481 gtctaaaccc atgaggtgta atacgaggca agttatattt tttcaaaata tatcttaacc
    33541 aatcattaac agtgtttgga atgtatagag tgtttttaac tgttgtaaaa acatgttgct
    33601 ctttagagct agtattgtat ccaagtttta aatactcttc tttttgctgt aatttccagt
    33661 tgttgaggat agaaagagtc tcagtatcta aagagataac tcgtctagaa gctcttgttt
    33721 tcggagattg aattataact ttaccaaatt catctacagc aagagtttta ttgacatgta
    33781 gttctttatt aaacgtgtct atgtctttcc actgtaaagc gagtacttca ctctttctca
    33841 tacctgtgta tgccaataat ctgaagaagg cgtattgttt catgttacca aaatctttaa
    33901 aagcatccag taaattatta agctcctctt ttgagtaaaa tttacgattt ttctcatact
    33961 ctttttttcg tggaagaagt gttttttcca taggattatt gtcaatatat tgcattgcaa
    34021 ccccgtagcg taaaatttgt gcagtctgtt ttctcatata atcgtaactt tcatatttac
    34081 tgtgccattc atctaccact ttttgacaat atgggacaga gatattcgat agtttaagct
    34141 taccaaatgc tggaagtatt tgattatttg cgtatcttac tgagattgcg attgttgaag
    34201 ctttaacact ggtacgctga tgagttatcc attcattata caggtcttca aatgtcatat
    34261 caggtgcttt ctttttaaca ccgtataata tttgatgtct gtactcgtca taatcttttt
    34321 gagcttcttg tttgctacta aaacctcttc tcgtagtatt tattttttca ccagttcgtg
    34381 gatcggtggc aatgtgtcct ttatacatcc acgccacttg accgtttttc tttttgtact
    34441 ttgatatttt tgccattaaa tcatctcctc ttagtttaca aggagtactt accactagat
    34501 ggtatcacct cccttcattt ttttcttagt gtattttttc ccaattgatg aaatcgtttg
    34561 ttctagcttg tttatattat cagtaatttc tctcacagct tcttcgggat aagacatgtc
    34621 tttcaattga ataggtagcc attcatctac cattctttct agtagttctt ctatactgct
    34681 agtgaggaaa agaatgttat tgtcaaattc ttctacaata gcattgatga ataattcttc
    34741 tatttttaag atattgaaaa gactaatttt ttcattttta actttattac aagtcttgtt
    34801 agcaataaat tcttgcatct ctggttctaa tttggaatat ctatccagcc atgtatctaa
    34861 attagagtgt actggtggga actgttgacg aagatgctgg aacaggtttt tatctggaaa
    34921 tgttatacca tctagtacaa tgctatctct ataaagaata attcccaaaa tatattcttc
    34981 tacattgcca caaactaact cctctatact catatttccc aaatcagcaa ttcgggataa
    35041 tcgctctggt attggtaaat aggttccctt ctcccattcg tagatagttt ttttgtcaat
    35101 taattgaccg ttgttaatca taagaccaaa tgctggttgt gttaattttt tactctttct
    35161 tatagctttt atttttgttc cgagtatctt ttttcgttct aaataattta ttggtggacg
    35221 ttttatcata ttgaccacac ctcctaaaat tagtatacct caaaaagggg tgttgtaaat
    35281 aaattttaca aagctgttga cacccctttt ttatcgaggt attatgtgta tgtcgatgaa
    35341 ctggtaatca ttttttgttt gattaatcgg ttaataacaa aatactttta ttttgagcaa
    35401 aaaatacgaa gataattctt agaaaatttg ttcaagcaat cacgaaagga gggggaaata
    35461 tgtctctaca aatcattgat agcattgttt ctatacaagt tgaacaacaa gtgaaagaga
    35521 taattacagt gctaaagcct atgctagaag acattatttc tggagtcact ctagagtata
    35581 tggactatca gcaggcaagt gaatatctag gtgtatcagt aggaacgatt agaaaatatg
    35641 tttctcaata cgggttacct gttataaaaa ttgatacggt cattagattt aaaaaatctg
    35701 atattgatag tttcatggaa cggtataaag gttgagtaaa caaataagac taaaacatat
    35761 agtaataaag agtttgtttt tattatctgt atgttttagt ctttaacaga attttataag
    35821 gaggaaacac aaatggaaac atcaatgatt aatattccaa tttatgtaga tcaagaaaaa
    35881 ttattagaga agccagttac aaaaaaagaa aaaactgatg taagagatag gtgtttagat
    35941 aactatagag aagttacaag agatgagttt gtagagatac taaattcatc acaatcattt
    36001 attccaagca agacaaagaa taaaggcaat gacaaggaga gttttgtgga aaccagagta
    36061 attattctgg atgtcgataa cactgttaaa gatgagaagg ggaaggtagt agatttgagt
    36121 aaagatgata gtagatactt aagcatagaa aaggttttat ctatcaattt agttcataat
    36181 tctgcgtttg cgatacaaaa aagtattcgg tactctgaaa atctagaaaa atacaagatt
    36241 gtctttctat taaaagaagc aattactgac tatggtaaaa tggttgctgt ttacgaatac
    36301 ttgaaaaaga acatccccgg gtgtgatgac aatgtaaatg cttcgaatag aatgtttttt
    36361 ggaggatata agtcagatgc agtgataata attaatgaag acaacatgtt agatattact
    36421 gagcttccga ttgattttac catgacatgt tctaaaaatt gtcaaagtga ttcagggaga
    36481 gagtatgaac tagtcaatga aaccgatttt gttaagttga taaaaaatga cgacaaagaa
    36541 gaaatgaaac agtggtttaa agactgcctg tttgattcct ccgacatgtc ttttaatgag
    36601 atttatgaaa gattgttaac cattgatatg aataaattac ttaagtcaag taaaaactta
    36661 agatgtctgt ttcacaacga tcataatccc tctgctagta tttttaccag taaaactggg
    36721 cattccattt tttattgtca ttccagtaat tgtgatatca gtgaaaattt tattggagtt
    36781 gtgatgctaa ttttaaagaa agacagtcgg gtagaaacat ttaattggct attagagaac
    36841 ctagacttgt atcctacaca ttttcgaaaa ttgaaagagg aatcaaaagt actttttgac
    36901 actcttgaat caatgaaaga caaacttttc aggacaataa ggaattatct agaggaaatg
    36961 cgacgtgtct atgatgtctt gctttctgat gttaattttt ttgatgatag taaggaaagt
    37021 gtgacttgta ttttgtcggg ggaacaatta gctaaaaaaa tgagttctta ctatggtaaa
    37081 acttatgaca tagataaatg taataagtta ctatcactta tgacttttat aggattgata
    37141 aaaaaattag atgatgaaga tgttcctttg aagatgctcg aatacctaaa taggttaaag
    37201 gaagagaaag cgttaggaaa ctttaatcat aagagaagca atgtctatcg attagacgtt
    37261 tttaatgcaa cttctgtgat tcaaaaattg aatgaagata tccttccact tctggaaaaa
    37321 attcatttta catatcaata tttttcttat gaatgggtta agatatgttt taacgaaaaa
    37381 gaggctaaaa gagtatttcc tcaaaattcc cgatcagaac tcagcaagga aaaacaattg
    37441 attttagatg aagcacatga agttttacag ggcttatcgt ggcaagggac atatctaatg
    37501 acagagaaag aacttattaa cactgtttgt gaacgcctac gtaatgttgg ggataacagc
    37561 gtgaaaaatg ctttaataaa aaacagaggc tactttgtta aacaaggatt cactcttgaa
    37621 cgagcttcta aggatattaa gaaactatac aatgtgaaag caagtagtag ttttttaata
    37681 tatttagcga aaggggcagg gatagatgaa acaataaaag aattgatatt atcaggagct
    37741 gggatagttc ctctgtatca atttacaagt gtaacaagag atgatggacg gagagtaagg
    37801 aagagaaaag acccaattgt attaaactag acaggttatc catagctctt aatcttattt
    37861 catctcaata cacccaccgt taaagttcgg tgggttattt atttttcaat ctttcaatag
    37921 ctgattgcgt tcattttctt gcctttttaa tagcttcata tagtcaattg ttcgaactgc
    37981 atcttcagtg ctaagagaac gatagagagc caaaaactct tcctcataat ctacgacaac
    38041 attgtctaga aaatggctta caggggttcc tagggctcta gaaagagctg ttaagctatc
    38101 gaggttaggc tctgttacag aattttccca tcttgctact gcctgttgtg tagagaagat
    38161 tttttcagct aattcttttt gtgtccaccc gagagctttt cgcttttctc taatgacctt
    38221 tgcatattgt ttctgtttca ttaatacacc cccatctcag tatagtacaa caagttgttg
    38281 tatttgtaat ggtatttgaa gttttttata ttttatgagt tgaaatacat catattgttg
    38341 tatataataa aacaggaggg gagaatcatg aaaaaagtaa ataatctcag ccgatacaga
    38401 aaagaaaaag gactttctca aacggagtta gcaaaaaaaa tgaatgttac acagcaatgt
    38461 gtaagttcgt ggcaaacagg gagaacgatt cctaaaccct atcaaatgaa gatgctttct
    38521 gagatattaa gtgtaccaat gaatgagctg ttttctgatg tatttaataa agtaaacagt
    38581 taactaataa gcaattgaat gattttagga ggagaagaca tgtattgtag aaaatgtggc
    38641 aaagaaataa cagatgaaag taagtattgc cagttttgtg gagcactaca agaaacagat
    38701 gagacaaccg gaacagacac agtaaagaaa agtactgagc agacaattaa tgaaatgaag
    38761 gaacaaatcg tacatggaca agagacaggg aagctgtatt tgattattgg ttggatttct
    38821 atggtagtat cgttagcatt tattcctgtt gtatttggtg ctgttgctgt tattatgggc
    38881 tacttatatc gagaaaaaga tgagaaaatg ggtacgattt tgatgatagc aggggtagct
    38941 ggagcaatct ttggtgtact tttagggatg tcaatgtact gataagaggg ataagaacaa
    39001 attattttgg agataggaga taaaaagttg aataaagtaa atatgaacaa gaagtttgtc
    39061 attataggta ttgttgtctt ggctattata ggtattattt tttcaaaaat gacaggtaca
    39121 tctggattag agaagtcatc aaaaccattg gtaacacaga ttttacaaga acagtacaac
    39181 ttaaatcgat catgtgatga tgtgacgatt actcatgaaa atggagataa cacataccgg
    39241 gctaaagcta tattagacaa tggaagtgct atcaacataa atattgagta ctatccaaag
    39301 aaagaccgta tatatgtgga gataccatat gctgaggtgt taatgttaaa ttgatttaaa
    39361 tgtattatgc ataccgtcca aacaggaact cccaaaggtg taaattcact agggagtttt
    39421 tatagtttcc tataaattaa atactaatac aggtgacaaa aaaatattac aatgattgtc
    39481 gggaattttt atgttattca ctgttataac aatataaaag aaatgaaaaa gaaaaaatta
    39541 ttatggatat gtttggtatt tttattgata attggtggaa tt
//
LOCUS       DAYNVV010000021        38222 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.021, whole genome shotgun sequence.
ACCESSION   DAYNVV010000021 DAYNVV010000000
VERSION     DAYNVV010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38222
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.021"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(578..1522)
                     /locus_tag="ACGXWR_001244"
     CDS             complement(578..1522)
                     /locus_tag="ACGXWR_001244"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFK0802827.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1818..2762)
                     /locus_tag="ACGXWR_001245"
     CDS             complement(1818..2762)
                     /locus_tag="ACGXWR_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFK0802828.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2983..4197
                     /locus_tag="ACGXWR_001246"
     CDS             2983..4197
                     /locus_tag="ACGXWR_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFK0802829.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASIYGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            4219..6234
                     /locus_tag="ACGXWR_001247"
     CDS             4219..6234
                     /locus_tag="ACGXWR_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-rhamnosidase"
                     /protein_id="HFK0802830.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEETFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(6317..7690)
                     /locus_tag="ACGXWR_001248"
     CDS             complement(6317..7690)
                     /locus_tag="ACGXWR_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFK0802831.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7716..8000)
                     /locus_tag="ACGXWR_001249"
     CDS             complement(7716..8000)
                     /locus_tag="ACGXWR_001249"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFK0802832.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(8002..10017)
                     /locus_tag="ACGXWR_001250"
     CDS             complement(8002..10017)
                     /locus_tag="ACGXWR_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFK0802833.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(10196..10501)
                     /locus_tag="ACGXWR_001251"
     CDS             complement(10196..10501)
                     /locus_tag="ACGXWR_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HFK0802834.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10590..11621)
                     /locus_tag="ACGXWR_001252"
     CDS             complement(10590..11621)
                     /locus_tag="ACGXWR_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFK0802835.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11828..12703
                     /locus_tag="ACGXWR_001253"
     CDS             11828..12703
                     /locus_tag="ACGXWR_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFK0802836.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12855..13697)
                     /locus_tag="ACGXWR_001254"
     CDS             complement(12855..13697)
                     /locus_tag="ACGXWR_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFK0802837.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13789..15666)
                     /locus_tag="ACGXWR_001255"
     CDS             complement(13789..15666)
                     /locus_tag="ACGXWR_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFK0802838.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15663..17084)
                     /locus_tag="ACGXWR_001256"
     CDS             complement(15663..17084)
                     /locus_tag="ACGXWR_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFK0802839.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(17087..20476)
                     /locus_tag="ACGXWR_001257"
     CDS             complement(17087..20476)
                     /locus_tag="ACGXWR_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFK0802840.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDDYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20733..22124
                     /locus_tag="ACGXWR_001258"
     CDS             20733..22124
                     /locus_tag="ACGXWR_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0802841.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(22197..22844)
                     /locus_tag="ACGXWR_001259"
     CDS             complement(22197..22844)
                     /locus_tag="ACGXWR_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFK0802842.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22852..23538)
                     /locus_tag="ACGXWR_001260"
     CDS             complement(22852..23538)
                     /locus_tag="ACGXWR_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802843.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(23544..24617)
                     /locus_tag="ACGXWR_001261"
     CDS             complement(23544..24617)
                     /locus_tag="ACGXWR_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0802844.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24839..25513
                     /locus_tag="ACGXWR_001262"
     CDS             24839..25513
                     /locus_tag="ACGXWR_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFK0802845.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            25518..26858
                     /locus_tag="ACGXWR_001263"
     CDS             25518..26858
                     /locus_tag="ACGXWR_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFK0802846.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(27007..27993)
                     /locus_tag="ACGXWR_001264"
     CDS             complement(27007..27993)
                     /locus_tag="ACGXWR_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HFK0802847.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            28717..29748
                     /locus_tag="ACGXWR_001265"
     CDS             28717..29748
                     /locus_tag="ACGXWR_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFK0802848.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            29857..31389
                     /locus_tag="ACGXWR_001266"
     CDS             29857..31389
                     /locus_tag="ACGXWR_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFK0802849.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            31528..32340
                     /locus_tag="ACGXWR_001267"
     CDS             31528..32340
                     /locus_tag="ACGXWR_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HFK0802850.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            32330..32815
                     /locus_tag="ACGXWR_001268"
     CDS             32330..32815
                     /locus_tag="ACGXWR_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFK0802851.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            32838..33383
                     /locus_tag="ACGXWR_001269"
     CDS             32838..33383
                     /locus_tag="ACGXWR_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HFK0802852.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(33456..35099)
                     /locus_tag="ACGXWR_001270"
     CDS             complement(33456..35099)
                     /locus_tag="ACGXWR_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFK0802853.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(35228..37456)
                     /locus_tag="ACGXWR_001271"
     CDS             complement(35228..37456)
                     /locus_tag="ACGXWR_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFK0802854.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            complement(37489..37968)
                     /locus_tag="ACGXWR_001272"
     CDS             complement(37489..37968)
                     /locus_tag="ACGXWR_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6530 family protein"
                     /protein_id="HFK0802855.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
BASE COUNT        11167 a         7211 c         6943 g        12901 t
ORIGIN      
        1 ttcataaaaa tatggaaaat atggattaat tttgaaataa ttgatttaaa aggaatacaa
       61 aagagtgaat agtaggaaat agtggtttag aactagtggg ctgatttttt atatatttta
      121 gtttacataa tatatattat acaaagtaga tttaaaaaat gataaacctc tctcgaacgg
      181 ttttttatca aaaatcgtca tttttccatc aaaatctgct tatgcaaaat tataaaaaaa
      241 ttttgcagtt tttcttactt tttttgtcgt ttaattgaat gataaaaacc agtttcttta
      301 ttcagttaat caaatatgaa cgaattagat atgaatcatt gtatttgccg ttgcggaagg
      361 attttttaat taaccacaga taaacattga taacgattcg cttattgtaa tcaacagatt
      421 aaatttcata tgttcatatg tacggataca ttttcggacc gattaatttt aaccattctg
      481 tttatttgct tacctattag atatcaataa aaaactgctt aacagctatt tcagctgtta
      541 agcagtttta ggatttttag ttcatattca ttgtttctta taatacagtg ttcaatactt
      601 ctcttaaagc acttgttgat ttgctgaaca ttgctttttc ttcttcgttg attgataatt
      661 caacaacttc acgaacacca ttttcgtcaa cgattgatgg cacacctgta aagatatctt
      721 tttcgtcgta ttcaccagtt aaataagcag atacaggcaa tacagcttgt tcgttattca
      781 agatagcttt tacgatacgt gcagtactca taccaatacc atagtaagtt gcttttttac
      841 gatcaatgat ctcataagca gcattacgga ctttatcagc aatcacatct aattcatctt
      901 gggcaatacg atggtctttt tctacaattt caaacactgg tttaccaccg acagttgtat
      961 gtgaccatgc agcaacttct gaatcaccat gttcacctaa gatatagccg tggacgctgc
     1021 gtgggtcaac ttttaatttc aatgcgattt ctttacggaa acgagttgta tccaatgttg
     1081 ttccagtacc gataacacgt gatgttggca gaccagattc gttccaagcg atatatgtca
     1141 aaatatctac tgggtttgaa gcaacaacga taataccgtc gaatcctgat cccatgattt
     1201 cttttacgat ttggcgcatg attgacgcat ttgttttaac taaatctaaa cgagattgac
     1261 caggtttttg gttgatacca gctgtgataa caacgatatc agcatcttta cattcttcat
     1321 agccacctga ccatacagcc acattttcat cgccccaagc cataccatct aaaaggtcca
     1381 atgcttcccc ttctgctttt tcttgattca catcgatcaa tactaattca ttagagattc
     1441 cttggttgat cattgcataa gcgatacttg ttccaacaaa acctgtaccg acgattacta
     1501 ctttacgact tgtttttttc atgaataaac agctcctttt cataactatt tgttactttc
     1561 atgaaaagta tagtcttgtt tattcatttt atcaacatgt taattataat agttgttatt
     1621 ataatttttg atggaaacga attcctgaat acgcataaca gataaatgac aaatgtttac
     1681 acctatatcc cctgataata caaccaaaag tttagaactg aaaataaatc caaaaaaatt
     1741 cgctgcaacg atataataag acagcaatcg cacctaaaac aattttcctt catatgcttt
     1801 agtgaaagat tttcttctta atgtttattt ctccattcat tgggagtaca tgttgaatac
     1861 ttcttgaata atttgaataa agaagtcgtt tgtttatatc cgatacgatt agcgatttct
     1921 tccaacgaaa aactcgtttc ttgaatcagt tccaacgcaa agtcgaattt tttctttaga
     1981 accagttctt gaaaggaagc atcaaaatac attttcaatt tattactaag atagaccgga
     2041 ttgtagccaa aatgagctgc tgtttctttt aacgtacaag aagtaaaatg cttatcgata
     2101 taatctaata ctctaagcat ctcattttct gcgcatccat ctgctgatga aaagctttgt
     2161 tgttctaata aatgagtcaa ttcgatcagt aatagtgatg tatagagatt taacgaacgg
     2221 atcttatgac tgtatgtatc aaaataaatc aacagcatat tttcaatcaa atgcgtcaaa
     2281 cgacttgttt ttccgccgcg aaaatgaatg aattgtgtat gttccccttt ttcttttgat
     2341 gcatttatca aaaaagaaga aagtagatta tttgtgcttg ccaaatgatt caatatctct
     2401 gtagataagg tttcttcttt taataagatg ttgattaaaa tatcctcttg ccctgtgtat
     2461 tcgattcttt gagtagcttc tttatcaatg atcaccacgt cactttcttc catctctatc
     2521 ctttctccat taataatttg taaacatgta ccgctataca tataattgat ttcaacaaaa
     2581 tcatgtgtat gctcgggaac ttccgcatat cgacggtgtt tactgatatg aatatttccc
     2641 tgttgaaata gatcccctcg gtggattttt ggcggtgtct gaagatggta agctaagttt
     2701 aaatcattga tattcattcc ttgttcacgc tgcagagttt cgattgattc ttcgttacgc
     2761 aaaaaaaatg tctaattcag ctagttccaa ttgactccct cctttttgta agcggtttct
     2821 ttcgcttatt agttcacgct gtactgctat tatatgcaaa gctatttttg gtttcataaa
     2881 gactttctat ggttgggaca tgaacttcct gtgattccgc tattgagaga ataaccactt
     2941 catactatat ttttgataag cgcttacaaa aatgaaagga acatgcttat gaataaaaag
     3001 atgatgaaat tttctctgct gtcagtctct cttattttga cttctgctgg tgcagtcacg
     3061 tctgcaattc ccagtatgtc agctacttat gccacgcgtt ctttatctgc tgttgaatta
     3121 ttaacgactg ctccctcttt tatggtcact atttttgttt tgattagtag ttttattgct
     3181 aggaaaatcg gacaaaaaca aactgtgatc atcggattag tgattgcatc gatttatggt
     3241 atcctccccc tcttctcaca aagttacagt attgtcttag cttcaagagc tggactaggt
     3301 attggctttg gattgatcaa ttctttggca gtcagcatga ttgctgcctt ttatcacgga
     3361 gatgaacgag cctctatgat tggttttcaa agtgcatttc aaggatttgg tgcagcttta
     3421 atgacatttg ttgcaggaca gctagtacag ttcggttggc aatatacctt tttagtctac
     3481 gccatcagct tacctattct tgtcttgttt gttttgtttg ttcctacacc tgaaacaact
     3541 gaacttcaat cacatggcac agccccaaca agacaagtaa tcaaaacgaa tcctaaaatg
     3601 attagttatg gtatttttct cttgctggtc atcgtggtat ataatgctgt atcgattaaa
     3661 ttagccacag tcctgacgac ttattctcta ggaaacgaaa ctaatgcagc gaatatctta
     3721 acaatcatgc aattggcaag tatggctgcc ggagtttgtt ttggctggct tcagacaaaa
     3781 gcacatcgct atatgcttac actttcttta ctactgatgg gaatcggctt tgtattgatt
     3841 gccactgtga taaacctgta tgtgattggg tttggtgcga tcctaacagg aatttctttt
     3901 tcgttattca ttccttactt attcaaccaa gtaagtatcc aagcgcccaa gtacgcggag
     3961 agtttcaata cttcaatctt attggttggc gctaatttag gtactttcat tgcaccatat
     4021 ggtttgctct ttctctcttt tgcttctctt gggagtaaaa cacttgctgt tttcgtcaat
     4081 ggcagtatct tgctgttgat tagcgcgctt attagccttc tagtagtaca caggacgaat
     4141 agaaagacag tgataagagt agatgaagaa ataaaagaac aattgacaac aaaataaatt
     4201 tgatggaggt cgtgtaaaat gacaaatgaa aaacataaag atagatggct ttggtatcct
     4261 ggagactttg agatccgcca tggactgcta caaaatttcc aacgggaaga acgaggtttt
     4321 gactggccag cgtactggta catggatgat tgccatcgga acgtcaagtt taagagatat
     4381 tactttcttg atcaaccttc catgtttaaa gtgacgatcc aaggagttgg gtatgtagaa
     4441 attaatggac aaaaacatcc atgtggaaaa tggctgactt gtccagctgg taaagcaaaa
     4501 attcgtatct ttgtaggaca tacatcaggg ctaccagcga tgtttatcga gggagacgaa
     4561 gtaaaatcag atattggctg gacagcaagt aattttattg aagaatatcc agctggctgg
     4621 agtccgcttt atgtcgatat cgcaaaagat ccaaatcaaa tctattatca aaaagaatgc
     4681 gtccatccag tcactgaaac ggagattggc ggaggaatct tattcgattt tgggcgagca
     4741 gtgaatggct gtgtagaact aatatctctg gatgaccata tcgaatctat cactctatgt
     4801 tatggagagt ccgatgtaga agctatggat atcgattatt gctactataa gcaaatagga
     4861 atgacaagaa aaatgaaagc tcgtaaacgc gcttttcgct atttgtttat accagaggtt
     4921 tctactggaa tggttcaact tcaagttttt catgaatttt tatctctttc gaaacaagct
     4981 gctttttcaa gcgattcttc tttactgaat cagatctggt cagtatcaga agaaaccttc
     5041 aagttatgta gtgatttgtt ttttatcgac ggtatcaaac gagatcgctg gatttggtct
     5101 ggagatgcgt atcaatcatt catgatcaat caatatcttt tttttgacga ggaaatcaat
     5161 aaacgaacga tattagcatt aagaggacaa aatgaaatca agcagcatat gaatactatc
     5221 gttgactatt cgatcttgtg gttgattggt atcgaaaacc actatatgat gacgaaagac
     5281 tatgaatttt tacgcatcgt ctaccctaag atgcaatcat taatgagata cttgatggag
     5341 caaacgaatg aattagggtt tatttatggg agagcaaaag attggatatt tattgattgg
     5401 tctgaaatgg ataaagaagg aacgcttgct gcagaacaag tcttattact gaaagcctat
     5461 cattccatga tcacttgcgg agatatctta gctgaaacat atggagagaa cgaaaattat
     5521 catactcatc tctatcaaga aaaatatcaa ctattgaaac aaaacctatt tgactacttt
     5581 tgggatgaag aacttggcgc ttttatcgat tgctatgaat ctgggagaag aaatgtgacg
     5641 cgtcatgcga atattttcgc tgttttattc gattttgcta acaaagacca acagcaatcg
     5701 atcttaaaga atgtcttatt gaatgacact atcacacaga ttactactcc atatttcaaa
     5761 ttctatgaac aagatgcttt atgcaaactc ggacagacga atatcgtcta ccaaacgatt
     5821 cttgattatt ggggagggat gttatctcat gatgcggtaa ctttctggga agaatacgac
     5881 cctactcaaa caggaaatga aaagtacagt atgtatggag atccttatgg aaaaagctta
     5941 tgccatgcat ggggagcaag cccaatctat cttttaggac gctattttat cggtttgtat
     6001 ccaacaaagc caggttatga agaatttatg atacaaccta atctagattc atttgaaaca
     6061 ctgaattgta cgctacctat caaagatgga aagatttcgc ttgaaaaaac aaaagataag
     6121 atcgtgatta cttctgatag aacaggcgga acagtgaaaa tgaatggtaa aagttatcct
     6181 cttctagcaa aacagccact tgtcttaaca agctattcaa aaataaatgc ataaaacaaa
     6241 aaactgcttg cgacatatca gaagacttta aatcttcttc tgatattgtc caagcaattt
     6301 ttattttgaa gtttgcttaa ttctgttctt tagaaacaat gtttgttctt tttccggcaa
     6361 aaagaaagct agataatacg acaagtaaaa agaaagcgat gattccaact gtcaaggcta
     6421 tttgaccgta ttctcctagt ttcccaagta caagtcctgg tactagataa tcagtatcgg
     6481 caaatgtaga agaagcgatt ttaagatctc ctaatactgg aaggataaat aatggcagcc
     6541 aactaatcaa taagctattg aaagcagaac ctaataccgc ccctcttcta ccgccagtcg
     6601 agttgccgaa gacaccagaa gcagctccgc agaagaaatg tcctactacc ccaggaatga
     6661 taactgtagt ttgcaagcct atcatagcaa acatggatag tgttcctaca aagaagctaa
     6721 caaaaaagcc aattaataca gcattaggtg catatggaaa aacgatagga acatctaatg
     6781 ctggtttaga atcgggtacg agttttttag caatcccttg gaatgctgga acgatttctg
     6841 ccaacaccat tcgaacccct tgaaggacga taacaaaccc agctgtgaat gttccagctt
     6901 ggatcagtgc aaagattaca gcgttgtctc cattgcttag ttctctttca acaaatccag
     6961 gaccagctaa caaagcaagt gcgacatata cgatcgacat caagagcatg atcgatacag
     7021 tagaatctcg caaaaagctg aaacttttag gaatctttat gtcctctgta gaacggtctt
     7081 tgtttccaaa aaactttccg atccatccac tagaagcata accgatattt ccggtatgcc
     7141 ctaacgcaac ttgattgttt ccagtgatgt tcttcataaa cggttgacaa agagcaggcg
     7201 taatagttaa tagtgttcct tcgaagaccc cgcctaataa gatcatccac aaatttgcag
     7261 taaaccccgc gcttactaaa atgactgctg ttagacaaga aacataaagc attgcttgac
     7321 ctgtaagaaa aatgaattta tatcttgtga atctagcaag taaaatattc acgatcatcc
     7381 ctactagcat gatcaaagca gtaggtgtac cgtattgttg caaagcaatc gccactactg
     7441 cttcattgct aggaactact ccttgagtat gcagagctgt ttggaacatc gaagcaaaag
     7501 gggttagtga attactgatt aaaccagcac cgccgatcag tactaggaat ccgacaaatg
     7561 ttttgatagt tccttggatc acttctgaaa atttcttctt ctgaagaacg agaccaagca
     7621 gtgcaatcaa agaaacgagg atggagggct gactgacgat tgacacaaac aaattcaaca
     7681 atttatccat tgatagttcc tcccttgaat catttttatt cttttgacaa gatcttcgtt
     7741 actttttctt ttacttcttc gctgtcaatg atcgattgca aaggtacgag cttttcatca
     7801 ggtatagaag ttagcgtatc tttcaaagaa tgctcaatga agaaataatc agccatatcg
     7861 ctagatacac ttccaacatc cgtatgactt acttcaaact cgtccacatc tgctccaaga
     7921 tctgcaagtg cttgtttgat gttcatctct accataaaac ttgttcctaa tccactttga
     7981 catactgcaa aaattttcat atcattcgtc tccttttctt atgatcgcta atatttcttc
     8041 ttttgttgat gcgtgtaata aatcttgaag attttgttta ttagaaagta gctttgttaa
     8101 atttgccaaa gcccgaagat gtgcctcatt atcgatagca gctaaacaga tgaacaaact
     8161 aatgggatgg gctggattat caagcagatc cacaggttgt tgaagtttca gcaaagacat
     8221 ccctacttcg tttacgccat cttctggacg agcatgaggt aatgcgatgt gatcgccaat
     8281 atggataaac gcaccatact gctccacgcg ctcgatcata gctttgatat aactttcttc
     8341 tattttattt tctgataata gcggctgtgc ggcaaatgtg attgcttctt gccagttttt
     8401 tggttgatcc gataattgga tcatttcttc tgttaataat tcagatagca taggacgttg
     8461 atcctccttc ttttctaaaa gtttgttcat tttacgattt aatacttgat agagcttttc
     8521 ttcgtctacg ccttctttta attcgatata aggcagtagc gccgacaaca attcttgggc
     8581 agaaggcatt gaaaatcctg gtatcagcca atctctttgt acttgattga tcagctgatt
     8641 tttttccaag tcagtcatga ttggatgcag aacatagaga gactttttct tatcagtaag
     8701 tgtgagaggt acagtagaaa aaataatatc gtaagaagtt tcgtcaacct cgtgtaagcg
     8761 gtcagctgaa ttagtctctg taaaaaagat catcgggaat aattgctgaa gttcactttt
     8821 taagatcaat gaagagctaa tgccacttgg acagacgatc acggctctta tttttctatt
     8881 tctttcttct gcgtccgctt ttctgatctc tccgccaaat agtatagtga aaaaaccaat
     8941 ctcttcttca gggatgctct tccctattcg tctttctaac ggaagtaatg cttttcttgt
     9001 catttcgtag atggaagcat attgatgctt aatttgatcg atcatcacat taggtaaata
     9061 aaaagaatag gaaatacgaa aataggcagg gaccaagtga taaaagacat tcatcaataa
     9121 ttcacgaaac gaagcaaatt ctacggccat caggaattcc atgcgatgga tgacttctga
     9181 agaacattcc agcaaaaaat caagtgcagg ctcctggaca tctccttcaa cgatcgatgc
     9241 taagcaaaga gagaaaaata taatctccga attttgatgt tcggaatagc caaggccagt
     9301 caatacttgt cgactaatgt cagtgactgc aagagaagcc aacagttcag catcttttac
     9361 cagttccatg gatgtttttc caattcgaat ggttgtcaaa ctcaaataat aagctaattc
     9421 atccattcga tttggtgcga atcgaagatc tgatagtgaa atcgttttat ctagcaaatc
     9481 tctaactttg gcgtaataat caatggaaag ggttgcggtt aaatacgtga gcccaaatct
     9541 tccagcaagt gactgcatca aacgagcagt gcgatttttt gcttctcttc ttaatattgc
     9601 ttctgaccct agcagcctaa aaccagtttt cctagtatac gacagctgac aatcttccac
     9661 ttctaattca tttcttatct ttttgatatc tgacaggact gtccctttag aaacctgaag
     9721 aaaatcttga aaatgaaaaa cagaaacaga cgttgcagtc gaataaacca tcaaataaag
     9781 aagatctctt cgctcttgtt cggtatacac agcttcaaat cgagtaatat ccaaaaattt
     9841 ttctgcccag tcgattgctc ggaatttctt tatacggata cgggtatcat ccacatattc
     9901 ggcaaaagga gttaattgtt tgatcgcctc gcttgtattt acttcgatga tctctgctgc
     9961 tttttctaga ctgatttctc ttggtgtttt caggagataa ctaattttgt agttcacagc
    10021 gctgttcacc tcctacttat attctagtat ggtagcgctt ttaaatcgag gggtgtttgg
    10081 tacaacttac agttggattt tttttacgac tgtaccgaac gatttctatc gaatggatac
    10141 agaaaaaaag caggtgacca aatgtctcct gcttttatga attgatttcg tccgatcaat
    10201 gatgatcatg tttatttttt gaggtcagtt cttcaaattt ttctttgaca tcttcaaccg
    10261 ctttttcgat atctttttca aagtgattgg gctcattagg ctttgtttcc tcttctacag
    10321 aatttgaacc agataaagct gtttctttat tttctgtttc accagagttt gtgccagcta
    10381 atgattcttc tttgtcttct gtttcaccag aattagttcc tgctaaagcc acttcttctt
    10441 ctgttttagg ggccattgaa cctcttaatc gtttgtgttt ttcaccgtca taatttgtca
    10501 tgttggttcc tcctagtagt tctatacttt ttcatcgtac aataagacag tttatgcgtc
    10561 aaaaaacaaa cccgattctt acaaatatgt catatttttc cttctgattc ttgaatgctt
    10621 ttgattcctt cttccaaaat tttcatttgt aagattgttt cttcatcttt gatgactttt
    10681 tctgcgccat taactaatgt ctcgtaaatc ccttcgtaga cacggctgta atcaccaacc
    10741 tcggaaatta ctttttcttc atgataactc ccttgttcat ctatataggt caatacacca
    10801 taatgttcgg gcaaatcgat accaaagtct tcatgatcag gcatgtaaaa cattttcaga
    10861 tgttcttctt gtcgatcttt tgtttgtttc acgaacatcc ctttttttcc gtaaacgacg
    10921 aaacttggac gttctttgat gcggaaataa ctggatttta tcgaaatttt catatttcca
    10981 tagaaaaaat ccagatcgaa gtaatcattc attcgtcctt tccctaaaag ttgacgtaca
    11041 tcatagctga tatcatctgg ttcgccgaaa taagaaagaa cttgatctac tgtatgacaa
    11101 gcatgtccat ataaatagct gttcgcagta gaaaattcat gcgtattttc tggtacttcc
    11161 ggtctgaaat aatcataatg catttctact tctaaaatat cccctaattt tccgctttcg
    11221 attacttttt ggactgtcaa gaagtcagaa tcgaaccgtc tgttttggta acattggata
    11281 aatagacctt tttcttttgc taatgcaaat aactcttctg cttcctttga cgtttctgca
    11341 aaaggtttct ctactagtac attcttacca tgttcgagtg ccatttttcc atattcataa
    11401 tgaaattgac taggtgtagt gatgacaact aattggatct caggatcatc ccaaagatca
    11461 gacagctgat cagtatattc gatgtcttcg aatgttttcc acactggttc agatggggaa
    11521 aaaatttttt tgatattgat tttgttcgta agttttcttg aaaaaggcaa atgatagcga
    11581 tttgtactct ttccattgcc aagataagcg attgtaagca tgagtggtgc ctccttttat
    11641 tgatgttttc agtatatcct agaaaagcgc agaaagtatt tataatagct attctggtaa
    11701 aaaagttcag aaaaacactt gttatcattc ggtttggtga aattaatgtt caaagtaagg
    11761 ataaaaatca aaaagatagt agcggaacca agtgtttatc agtaagatag aatttggagg
    11821 tcagatcatg cttattgaag aaaaactaac aaaacaagag ttgtttacca cgacagagaa
    11881 acggattgtc gattacatcc gtaggaatat cgaagctgca gtctacatga cgattgaaga
    11941 attagcaaaa gctacgtata cttcccattc agctatcatt cgtttatgca aaaaaatggg
    12001 attcagcgga tttaaagaat tccgtttcga gctggggcgg gaagttcatc aattgattgc
    12061 tcagttcaat caaacgattg atcctaattt tcctttttca agtgaagata gcactcagca
    12121 aattgcaaag aaaatggcgg atttatcgat ccagtcaata aaaaaagcac aattgcagat
    12181 tgaacatgaa gatttagatc aaatcggtaa agtattgaac aaggcacagc gaatctttct
    12241 ttttgcaaaa ggtgattctc aaatcacggc aaggaaattc cagaataaaa tggtcaagtt
    12301 gaataagttt ttgatcatgg ctgaagaata cagtgattct tcttggaatg cagccaattt
    12361 gactagcgag gattgcgcca tttttattag ctacagcggt cgcatccatc attatgaacg
    12421 aataatgacc tatttgaagc atgtagaggc ccctaccttg ctgattaccg gaaatcagca
    12481 ttcagaaatg gccaaacagg ctgatatgtg tcttgttata tcgcaggagg aatatgattt
    12541 tgctaaagta gcgactttct cctctcaaat tgccttcgat tacgtattaa atacgttatt
    12601 ctcagtgata tattctcaaa attttgaaga gaatatccgc aacttgaaaa acaaacaaga
    12661 attgatgcaa aaaggccttc ttaaagaata tcggaaaact taagaaaaga tcctcattta
    12721 gtaataagaa agatagtgtt tgataggctc tctttgatat catcataaaa acaggctgaa
    12781 gttttctttt tcaaacctca gcctgtttgt ttacggaacg attcgaatag atatattata
    12841 gaaatgagga atagctaact tctgtttctt attttgaacg attgacgaaa aagatatata
    12901 agaaggagga aaatcagtat acatgcagct aacaatccat acaggaaaaa tcgtttgttc
    12961 tcggatactt tctgtacttc tttttgaact tcttttgcat gataaggaac ccggtgccct
    13021 ctgacaagta agcgatgact gttgaccata taaggtgtac aagttaggag tgtcacgaaa
    13081 tcctgccctt tttcgattct cagatctttt gtatcagtcg gttctaccgt cttgatctga
    13141 tcgacttgat aagcgagtgt ccgtccattg atttcgatat agaaagaatc acctaaagtc
    13201 agtttcggta agtctgtgaa caactttgct tgaggcagtc ctcgatggct ggaaataacg
    13261 gcatgtgtat tttctccccc cgtaggataa gacgttcctt ccaataatga ggcacctttt
    13321 tctagcagca cagtattcgt ttcatcaaaa attggcaaat ggacattgat ctcagggatc
    13381 gtcaaaatac cgatcgtatg tttctcaaaa taggttctat cctttttcgc aggttctttt
    13441 ttcttagtaa agggatctgc acctggattt ccaccttctt ttgctaattg ctggtttttc
    13501 tttgtcatgt tttcttggat tttagccatg acttcttcat tttctttgac cgcttgttgc
    13561 tgataatgag agatgatctg ctgatccaga taattattca gcgcgtcgct aacaaatgga
    13621 taagctagta tccctattcc tgagagaagc aagaaaagca tcagcagatc tagaagtttc
    13681 cttttctttg gtttcatttg tgttctcctt gtgatgactg tttgataata aaagaaaaag
    13741 gagcatttgc gtaatccgct gctccttttt ccaattcttg caaaaagact aaatctgact
    13801 gtgcttgcgt ctagcaaagt acagtccagc aatcagtaga aggactactc ctgcaccgat
    13861 atacacatag attcccttac cgcctgttga aggaagtgta cctttgtgtt tatttggtat
    13921 tttttcagga gaaatcaact gtcctgctgt tacataagat tgttcatcga tagtaaatgc
    13981 tacacggttt gttaatggaa catatttttc tggcgctttc gtttcttcca gatagtacgt
    14041 gccatatttt agacctgtca catcgattaa accgttactt gtggttgtaa aaaccgttgc
    14101 tgattctttc gccgataccc agctgacggc ttttgtggat gggtcgatcg ataaatattt
    14161 cgctgtgtca ctatcttgat cacgaacgac gaattctgct ccagcaagtg tttggtctga
    14221 tgtaacgtca ccatctactt taacaaatcg tttgccccca gtaacgacat cgactgacgg
    14281 tggtgtttga tcatttgtat gcccgttatc gacatttgct tggttagaaa atcctttggt
    14341 tggatctgct ttttcgttca aatgcatata gtaaacgaat ttcaatgtac cgccaggagt
    14401 taatgaagga atataattcg gatcaactga aaccgtgaat ccgtctgttt gctcagtgac
    14461 agaataattt actgggtcga tttctttatt tccatcatat aaggcataag catacgttcc
    14521 tgaagaatca ttatcaaatg ttaaagcagc gtcatgagta tcgataagtt tgaatgttgt
    14581 gtacttgttt tgcgttcctt ctttatcagc gatacctaat gggatattga cagaaatctc
    14641 atattgaatt ttttcaccga ttgcgacatc ttttccattc aattgaggtg ttgttttatc
    14701 aactttagac gtatcatttt tgatggtctt ttctactggt gtttggctat ttgccaggat
    14761 ctcaaaaggc gtgattgttt gcttttcaat catttccgca ttatcaggag cttttacttc
    14821 ttctaaatta tattttccaa cttctaaatg attaacgatc aactggcctt tttcaataga
    14881 tgcctcggca aagtcattgt tgccgatgtc ataagaatga ccagtaatga aatgtttggc
    14941 tttggtttga tcagttgtcc aagtgtacaa tccatctgtg acactttgga tgtatttttt
    15001 gacgcttggt gttccttctt ctttagaaat aataaattct gctccattta gtgcttcgtt
    15061 ttcggcagta ccgatttttg taactttcaa cgttccatca ttaccgactg tatttttagg
    15121 gtagagatgg atagtatcta gttcttctgt cccgtattta taagagccat ctgcttgttt
    15181 gatcatctca tatacaggga aagctaaaac catgtttgcg gcagctgaca ctccgtcttt
    15241 tggttcttct ttgatcgtgt agactgcatc tttcccattt tgttttttag gtaaagataa
    15301 agtgacattt ccatcagcat ctgtcgttcc tgaagcaact ggtgtaccag gagtcaaaga
    15361 ctggactgct tgttttgctg catccacgga cgctccttta tctcgttgcg cataaaattc
    15421 ttgagtgacg ttataaactg aaaatgaaat atcggctaat ccttggtatt gatcgaattc
    15481 gctcatttct ttcccgctgt tttggattaa aggatcgggt aaatcagtca ttttcttttt
    15541 atgaaggatg acttgagctg ctgtctcctc tgcaaacact ttttttgcgc cgaagctgtt
    15601 tgtgagtaat ggtaaaataa ggaaaaggac tcctaacata acgtttattt ttttatgatt
    15661 tttcattttt tcactcctgt tctttttttg ataaacaacc agattgcaaa gcttgcgaat
    15721 accataccaa caacgcctaa aagtgtattt ttcgtttcgt ttgtttttgg aagaaatgga
    15781 cggctatttt cttttttatt gactactttc aatatactgt ccgcctcttt atcctcagaa
    15841 agaaaagttg aaatggtaaa cggaatttct gtttcactta aaatataacc agaaggtgct
    15901 tcgatctctt ttaatcgata acttcctgtt ttcaacccgg aaattgaaaa agcgccattt
    15961 ttatcggaaa tcaggtgaag cgcatctgat tcgttctttg tccacttgta tccgttggct
    16021 gtttgctgga ggtaatttcc tgctttgttt ttaataagga atactgcgcc agctaatcgt
    16081 ttatctggtt tatttgtctc gattttgaca aattgcttac tccctgtata tacagagact
    16141 ttctttgtac tgacaccaaa accaaaatcc agtgttccgt tgttgttgat ttccttgttc
    16201 gcctgtgctg tactgcttag ctgcatctga taagaaatgg tcagtttttt tccagcatat
    16261 ttttccaacg aagggatcga aaataaaaca tcaaatccgt gaggtttctt gtgtatgaca
    16321 aagccttctg tcagcttttc tccattcgat gaaatcgtta aactattagg taaaaacgtt
    16381 aatgcttcat ccgcactatc tgacaattcg aacttttgat agtcaaggat atttacagga
    16441 attgtcgtat gcaaggaata agtgattttt tcaccaatcg taaaatcatt tctaggctct
    16501 tctaatacct tctcaaaagg tggatcaggg tagtcgtttt cttcattttt aggatacaaa
    16561 tggatagttg aaagtttttg attgttttgt ccatgtacag gaagaacaac taccatattc
    16621 tctgcctttt ctttgacgac ttctggtact ttggattcaa tgaaaagata cgctttatct
    16681 cttttttctt gatctttagc ggccagagaa aaagaagcga taccatcttc gttgttaaga
    16741 gttgtagttg ttgcttctgc ggtaaacata ccggaagacg caccgttttt tgcgatctct
    16801 gcttgtgctt cttctaccgt tttgcccttt tcccgtagat ggtaaaaaga atctgtgaca
    16861 tcataaactt ggaatgtgac accatttaat cctcgatacg tttgtaataa agctttttct
    16921 tgtccgtcat ttggatgatt tttcggcagt tgcccgtttg ggaaaagcaa tttgtgtaaa
    16981 gtaatctgaa ccatttctgt ttctgtttct gttgctacct gagtaaaagc tggtttaaat
    17041 agtaacaaga agagacacat actaagccaa ccaagttttt tcatatttag ctgccccctc
    17101 tttctttttt caaaaaaaga taccaaatag aaaacgcaca accaatcatc cctactagat
    17161 agattcctaa acggccaatt cctcccgttt caggtaatgg tacttttgcc tgattcgtga
    17221 tgtctaaaga aatctggttg tttttggctc ctggtgacag aacagattca tgatcttgtc
    17281 catccacttg aattgaccca tcttcgtgta taactatagt aactggctct tttagacctt
    17341 ggtatccttc tggtgtaaaa gtttcggtca gcgtataagt tccaggtttt aaattttcga
    17401 atagaaaggt atctgtttct tgtccatctt ttggcgattc taagtccatt tctggtccct
    17461 gcagtctgaa ttttgctcct tttaatgtct gtccgttgtc ttcttttttg tgtaccgtta
    17521 gatcaaacgc ttttagtcga ttttgatgag tgagcgtcca tacattattt gtcatctcgg
    17581 tattttttcc cgtgtaaatg atttttccat atttatcgat ttggaattca taatttcccg
    17641 gcgaagtatc atatccggca ggaccagctg tttcaacgac tcgatattta ccaggtgtga
    17701 gtgaatcaaa actggcaaga cctttttcat tcgttgtttg gctgtcaatt ggctgataag
    17761 taccatttgc ttcttttttc tgtagggaaa atgctgctcc tttaagattt atctctttgt
    17821 ccgtcccttg catcgcatac ttacgtactg ctacaggaac ttcaacaaaa ggattttcaa
    17881 tagtcaactg gatcgtatca tcggaagtag tgactgtttt tccatcaatg gttaccgtac
    17941 catcagaagc gatcttgatt tcccaagtag tctttttgct taatccatgc ccttctggag
    18001 cttttgtttc tgtcagcgta taggtcattt ctttttgcaa tttgacattt tctggaagag
    18061 aataggttcc gtcgccatga tctgttagta aagtatcaat agaatctcct gttaatttga
    18121 aaacagcgcc aataagatcc ttttcacctg tagaggaatt tttcgttatt ttcaagttta
    18181 acggtgtgaa ttgtttagta tttttccatg tcattgcatc tatttgttga gaatcgtatc
    18241 ctggtacagg taattctttg attgtttggt aactgaatgc ttgaccttga ttattgtatt
    18301 gaggtagtga taatatctct tgataacttt ctccgctatt tgcagataat ttgtcaatgt
    18361 ctgcacgttc ccacgtattt gttgtatctt tagctggttt aatgattcga atgtatccgt
    18421 ttttccaagc tgcagcattt gtcgtatgtt cccgttgaat ctcaaaagta acttgatctg
    18481 gacgatcagc tagattgttg tcaaattctt cccataactt tttgatgtga agactgactc
    18541 cgggagcttt agcagatggt ataccgaatt cagctaattc attggtatca atgtttggct
    18601 ggaaagttgt cctgccgttc atttgatacc agaaatttgg atggaagtcc tcattttctg
    18661 tttggattct cacttggtaa tggatttgga tttcttggtc ttttcctaaa tagatctgat
    18721 tgctcttgat ggtatttcct tctatggaaa tagatggagt gaccgttgta ggacttgtcc
    18781 ccacactctt gactgaaagt gtaccaggct gataaatgaa tggttctgcg attggatcat
    18841 ttatttgtcc attgcttaca gttgctgaga tctgtacagc ttttttggct aggtattcag
    18901 agatatctgt tgcatgatca gctgattcat agtaaagatc gcctttttca tctgatgaaa
    18961 ccatttgtcg catacgagac tctacttctg cttttgagag accagctgcc ggatcgcttt
    19021 gaagttggat gccaagacca tgtatttcga ttcctcgttc tttgagtgcc atcgcttctc
    19081 cgatggttgc gataaacgta ctgtcgattc ttctggatag attgttttgg tcaggtgcat
    19141 catagattct tgagattaga gaagtatttc ccggccgatc ttgcgtatta gaaaactgag
    19201 ttccgtaata attgctgctt gattgtgcgt gtacccgctg tactttatag gaaaatgttg
    19261 gtacaccatc cgtcagcaaa acgatcactt ttttatgtcc atttggaacg gatagcatgc
    19321 ttcctgcatc tcttagtgct ttttgtgtaa aagtaccacc atttgtccgt gaaggtgtaa
    19381 tggattttac ttgatttttc actgaatcaa atgaacccat ctgtactgca ccgttactgt
    19441 agctatatcc ttcgcttgag tagccgacat atcccatatt gattttgtct gtgataccgc
    19501 tatctgctaa agtatcgaca aaacgatcga caccaatctt tacttcaccg atccgattat
    19561 tgtcgttcat acttcctgac cagtctacga ccaatacgag atcaagaggc gtgatatctt
    19621 tttgtacatt tccacgagca ttcaaataaa catcaaacaa tccgggtgta cttgtttcct
    19681 ttgcatactt tcgtatcgca tagtctgctt gattaccggt tcctccatat tcgatatacg
    19741 aatgggtccg atcattagga tctccattcc aagaatttat accatcccat tgatttgttc
    19801 cgtttttatt gccttgatga tcaagaacat ttgtatttcc tgtaggttgc caactggctt
    19861 taggataagt gccctgatca tctgttgtat attctgtagg aatcgtttga ttagatggca
    19921 cactcacagc tggcaaggat aatgtaggca atgtaaatgg gctgacagaa ttttcgtttt
    19981 cttttgatga ttcttcttct atttcgtctg gctttggtac tgacacatct gtatctttct
    20041 tattttctgt ctcatcaata atgtcatatt ctttattatc gacgatcagc ttgtttgcct
    20101 ggctgtggta aagtgctgga tcgattggaa aactcagatc gatagtttgt ttagtgtttg
    20161 atgagatttc caacgtaatt ttcccgctat ttacctgata agcatagtca tctccttctt
    20221 ttctttccac atcacttaag taattttcga ctagaccaat ttctttttct atcttttcag
    20281 cactggtgtt attcgcattt agcttgatgt tcagtgcttt ttttccagac tgatccgaaa
    20341 tgacttcagc tgaaattgtt tctaaaactg ttggatcatc tgtagtgtct gctattgcag
    20401 ataatggcac aaagtttgat aaactcaata ttatcagcat gaaaataact ttcagtttct
    20461 tccctgtggt cgtcattttt cccctccttt ttcttttttt ctgttttgac gtgaatagtg
    20521 aaaattatta aaataaacag gcgttacata attttattta ttttaatatg ataattatta
    20581 tacgaagggc gctaaaggga atcacaccaa ttttcatacc aattggtttc atttatgaag
    20641 ttgattcctt cgattaatga gcgtttcatt gaaagaaaag ggttgaggga gaaaaacata
    20701 tgatcaggtt gttggaatta aactatagaa agatggaaaa aatcattcga attctgtcca
    20761 tttctgacaa gtggatgact aaaaaagaac ttgccaaacg aattggtagt tcagaatcta
    20821 catttgtaag gtatatcgaa gagatcaaaa tccgctgggg aacggatgta acgattcaat
    20881 cttcacaaaa attggggtat cgtcttgaac atttgaatgt accagcttat ttaaatgttc
    20941 tgatggaaat gtcgcaaagt tctacaaaca gtcgtttatt aaatgagatt attgtcaatc
    21001 cgggtaaaac gattgagtat tattgtgaaa aaatttccat cagccggtct tcttttacac
    21061 gtaagttgaa acaatgcaat caaattttag aaagctattt attaaaagtg atcgttgacc
    21121 aaggttttca gttaactagc cttaaaagtg agctccagtt gcgtatcttt gttacctttt
    21181 tctttttaag ttactacgga agacgcacgt tgccatttcc aatcgaaaaa aagaagatca
    21241 aagaaattat ggtcaagaat aattgtcaga tgaatttgtt tcaggaagaa agcccatatg
    21301 agcaatcttt ctttattatg tattttgttg tgcatctcat gagagaatcc caaggaactc
    21361 catttgaatg gaaagctgga gactcttatg tacagttgat aaatatcgat aaaaaagact
    21421 tcttaatctt gaaaaatctc ttaggaaaat tgaagtacag cagctatata aaagtagtga
    21481 actattttgt caatacgatt ttttcagaat tttcggagaa agaaaaaaat gaaatcagtg
    21541 agcagatacg aaaaaatatg tcctactgtt cgttttcatc cgctgattgc aaagaaaaaa
    21601 acgaagaata tgttgttcaa ttattaacgc aaatttattt tttctcccgt attttcccat
    21661 acgatacgac tcatttgacg atccgtgcaa cttactttgc acagcagatg caacaccgcc
    21721 agatacgtct atatgctgga tttcgtgcag aacttcaatt ttattccact ctactgaatc
    21781 agaatctgat ttattattta tctagctata tcttttggat gcttatcggt aatcctgaaa
    21841 ttcaccatta tacttctgat aaaaaaatac tgattatcag cgacttaagt cttcgacata
    21901 gtcaatatat tgaagaatat atcagtgata ttcttgctgt gcataaaatt cactctgaga
    21961 caactgctat tactgaagat cagctgtcga aatacaatct tctcgagtat gatctgatcg
    22021 ttacgaatca acccattttg aatgcccatg ttcctcatat attgattgat gatagtgtgt
    22081 cattcgcaaa tgaagaagaa ctcatccgct tattcgagtt atgaataatc aaaaaacagc
    22141 tatgtataaa ccaccctgat aaaaatttca ggacaaatac acatagctgt ttctttttat
    22201 tgtattcctt cagcaatcca acgagattta tagcgaaagt cttttaacaa ctcttctttt
    22261 gtccaattat ttgcaatgag atccgtcaaa gtgttcatta cgagggtcat ggaaaagtat
    22321 aggaaactaa ctgcttcttc cgacgattga atggagaaat gattgattct taataattcc
    22381 agccattttt cgttcattgg agaatcagcc gatagttctc tacgtttggt tgtctgctga
    22441 tcatttcgct gggttaacaa gtataacctt tgccaataga tactttcgtg atctaagtcg
    22501 cagcaccact ctaaatattt ttcgatcccc aaaaagaaat gttgtttgtt ttcgctaatg
    22561 aattttaaga tatcttgatg gactatgtga gaactgcttt tgatcgtata caaataagca
    22621 tcttccaaat cttgaaaata tttataaaaa gcaccgcgcg acatccccat cttgtcaacg
    22681 atttctgaga ctttgacttg gctgatgtgc tgtgagcaaa atatctccag taataggtca
    22741 tcgattctct gtttctttgc gttcgataaa ttgaaaaaag tttcttttgg catccacatc
    22801 tctcctttat ctctgattat acgtggatag cccttcattg tcatgaagga ttcattcctt
    22861 ctttttctct tcttctgtca agtacccatc ttccattcga taaacgcgat cactccattg
    22921 aatcatacgg acatcatgag taaccataat agtcgctttt tgtttctcat gagcttcttt
    22981 aactagtaat ttgacgactt catatgcatg atctgtatcc aaactagctg ttggttcgtc
    23041 tgctaagatc aagcttggct cattatataa agcgcgagca attgccactc tctgtctttc
    23101 tccaccagaa aggtctttag gataactatt tttaagtgac tggatatcta aagattgcag
    23161 caaggaatcg atttttgttg aatcttcttt ttttgaagta acttggtcaa ctagttcaaa
    23221 ttgttccttt accgttaaaa aaggaatcaa attagagctt tggagaataa atcctatttc
    23281 tttaaagcgt aaatctgctc gttttttttc tggaagctca gttagtgagt gaccgttgat
    23341 cactatttct ccggaagtcg gtgtttgcaa tcctcctgaa atggtaagga aagtactttt
    23401 acctgaacca gaaggaccaa tgatgctgac gaattctcct tcctttacat aaaaatcaat
    23461 tgctttcaaa gctgagacct ttgtatgacc agaaccaaat gttttggtaa cttttttcat
    23521 cgttaatatt tttttcattt ttattaacct cctattgctg taattgggtc tactttggtt
    23581 atcgtacgta tcgaaaacaa tccgcctagc attgcgacaa tgatcaaaat cccactatat
    23641 agcaaccatt gtgaccaaaa aacagcaaaa ggcatcgcgc ttggtaaaat cagactagtc
    23701 aaataagcaa acaaaagagc aagcagaacg cctaccaccc caacaataaa ggactgtgct
    23761 actaaagatt tagcgatgaa gaaatttttg atcccttgtg ctttcattac tccaaaaata
    23821 gcagtcttct gaagtgtcat cacgtacatg aaaataccga ccacggcagc aaccactaag
    23881 aacaaaaagt atatcatcgc atttaaggtc atattttggg cagaatagcc aggaatactt
    23941 tcaatgaatg tcccaatagt taataactgt agacccttcg atgctttttc tttcgaaatt
    24001 ttagctgaat cctttattac gatcccattg atcggctgtt cttcttcaga agcaaacggc
    24061 tgttgtccat acttcaaagc agtccacgta tctagggacg catagatgac gggagaaact
    24121 gtgtaataag tttcaggaaa gataccgaca atcgtcaaag gatcgtcgta actgccaatt
    24181 ttgatcgtat ctccaatttt atagcctgaa tcagccagat tttgagagat gatgatttca
    24241 ttctttgttt taaattcatg ccctttcgtg agttttggta ataaaaatgc ttctttcgtt
    24301 gtgccgaaaa ctgtaacatt ttctttgttt tttcctttga ttgctccgct gtacaatccg
    24361 attggtgctt tctctcctcc ttcaatgtat ttcagatctc ctcttgttaa ttgtgaagct
    24421 gcaaatactt gatttgcatc ctccgacaaa acaatctctt gtgcgtccca atcatcgatt
    24481 gcttttttaa actcttctga aagtccattc gctagtcctg acaacatgaa tacgacatac
    24541 gcaatcaaga acataatacc gacgatcaag ccatatcgta atttagaata gcgaatttct
    24601 ttgatagcta gaaacatttg tttttcctcc ctatgataga ttgatagtga caaaatgtca
    24661 cttgttgaat agtgtaactc taaagtgaca atttgtcact tgtgttgttt ttttcttatc
    24721 aataaattgt ctaagacatc tttcgataaa accttaacat gagtcataaa aaatttattt
    24781 aagccttatt tatgctttcc atgataaact aaagtgacca aatcaatgag gtgggaaaat
    24841 gattaaacta ttagtagtag aagacgataa agtattatcc aataatataa aagaaatact
    24901 cgctgcaatc ggcgagataa cacaagttta tgatggtagt gaaggactgt tcgagttgga
    24961 aagtggagtt tatgatcttg caatcttgga tttgatgatg ccggaaatga atggatatga
    25021 agtgttagca aaaatacgga aagaaaaaat acagactcca gtattgattt tgactgcaaa
    25081 agatagtttg gaagataaga ttgaaggatt tgaacgaggt gcagatgatt atctaacaaa
    25141 acctttctat cgagaagaac tgatcatgcg cgtgaaagca ttattgaaac gctcgctagg
    25201 tctctttgat gaaaatgttc tgaagtataa ggatatcagt tgtgatttaa aaagcaatga
    25261 agtcttgtat aaagaacaag ttttgcccat acaaggaaaa gagtttgaat tgctcgttta
    25321 ttttttacaa aataagggaa tcattttgac aaaagagcag atatttgacc ggatctgggg
    25381 atttgattct gatacgacga ttacagttat tgaagtttat atgagcaact tacgaaaaca
    25441 tctgcgaagt actggattgg ataaagaaat caaaacctta cgtaatgtcg gttatatact
    25501 gcaaagggtg tgatgcaatg aatggagata ttacacgaaa gcaacgtagt cgcttttttg
    25561 cgacaaatgt agcagcattt gcttttatct tttttctttt gggattcatt actttacaga
    25621 tattaaacca atctgcatac agagaaacag atctgtcatt agagaaaata aattttgatt
    25681 ctcgaacagt acaattagag atacaaagat atcagcaagg cgatcccttt ttaaacccga
    25741 ctcaaacgga acaaaacaga acaaacatgg aacagccatt aatggaacca tcaaatgacc
    25801 gttttaacac tcaagtgatc ttgtggtcta aaaatggtga gatattgaat aaagcagcta
    25861 ttggtgggcg tttcaaccaa atcaaagaat taaaaatgga tacgaaaaat ctgaatacca
    25921 tccaaaatat tgaattaaat gaagacagtg gctcatctgc cctctctttc cgttcgatta
    25981 cgaaaaaagc ggagacgaat caagatggcg ttgcctacat ccaaatttta gaaaatacaa
    26041 atcaaatcaa gaattcatta gcgacttttc gcacgattat gattttgtgt atgattgttt
    26101 tttggattct ctctattggt atcagttatt acttgtctag tctaagcatg cgccctatta
    26161 ttctttcttg gagaagacaa aaagaatttg ttgagaatgc ttctcatgaa ttgcgcacac
    26221 cgttaacgat tattcaaaat agtttggaac atctttttac caagcctaat catactatta
    26281 ttgaagaatc cgaaagcatc gctcaagcat tgtcagagac gaggcgcctc actggattga
    26341 cttcggattt gctgacaatc gctcggaatg attctgatca gcagctgctt tcaaagcaaa
    26401 tgatcaatac acaagaatat atcgaacaac ttgttaaacc atttcaagag atggccatca
    26461 tagatggaaa agagtttatt ctccataacg atgcaacatt agaagtacca attgatgaaa
    26521 aaaaaatcca tcaagttttg gttattttgc tggataatgc attaaaatat acgaatccag
    26581 aagataagat cattttggat tcatctgtta accataaaga atggctgatt cacgtaaaga
    26641 atactggccc ttctatcagt gaagaagatc aagcaaggat ttttgatcga ttttatcggg
    26701 aagatcaatc tcgggcgaaa gagactggcg gatacgggct tggcttggca attgcaaaac
    26761 aggtaatcga acagcatcat ggacagattt ctgtatccaa ttatcttcca caaggagtcg
    26821 attttaaagt ccaattgccg ttgaagccta aaaaataatg cttatcccta aaaaagggct
    26881 gtgacaaaaa tcttgtcaca gccctttttt gttgcgaata aacggtgttc cagaagtagc
    26941 ttcttcggaa ataagccgaa atttctttaa gctgaccact tctgtcacaa cctctttagc
    27001 ttacgcttac gattttttat tgcggtcttc aatgtgtaca tcaccgcttg tgtcaatatc
    27061 caattcttct cggctaacat cttctgtcac tttttcaaca tcttcatgtt cttctttatg
    27121 aatcccaact tcttcacgaa taactgtatg tttgcttaca tctacttgct cttctttgat
    27181 tgggatagta atcgtgtcat cttccaattt ttcgtctgtt ccctgtgaag attgatctgt
    27241 tactggtttg cgttcgatga cgatttcttc acgtttgacc ggtacttcta ccgtttcagt
    27301 atcgttgacc acatgtttgt ggatgtcgac ttctccagtt gtcacatcat gtgtatttac
    27361 atctaatttt tcttctttta gttgaattgt atcatcatct agatttggtt tgcgatcgat
    27421 gtcttcagtc ttgcttgtac ccattgtatc agtctcgcca ggtacgtcca tcggatcagt
    27481 tcctggtgtc atattcaatg gatccgttgt attttgaaag cctgtcgtgc cacctacgtc
    27541 cattggatct gttccagtgc cagtttctaa tccagtcccc attgtgcttg ctgggctaac
    27601 agtatcttgt gtatccattg tatcttctgt tgtttctggc tgacgatagc cttttactgt
    27661 gatgacaaat tttccatcag aaatatctcc tctatattga tataaaggat cattttctgg
    27721 tgtagccgtc tcagaatcat aggtatcaaa agaaaaagta tcttttattt tttcccataa
    27781 agaacggtct tcttcaccat ccatccgatt ttcatctgtt tcaacatcta taccagacaa
    27841 tccgtcaaat cctagtctag atgctgcttc atcagtagta taaataacga tatcatctcg
    27901 ttcataccct tcgttacgca accgttcaat tactgataat gcttcttccc tcgtactata
    27961 gcttccgatg accgttaaat ttttctcttc catgtaaatt cctcctagca aatagattta
    28021 tgattggtat attgttactt ataaatttat tctataggag acgattgttt tctacaaata
    28081 tttagattgg aatttgatta aaacaattta attgaaattt gaaaacattt atgttaatga
    28141 aagtcatatt ctaataaaat gtcatttgtt tctatatgaa tttttatgaa aaatttcata
    28201 taatttccac tcgttgtgat ggtttaattt atccaatcca tcaataagca aacaacttat
    28261 ataaaaaagg attaattctc aatataattg ctcctaccat agaataaatc ttcatgtaaa
    28321 gtaatgaagt accaactatt tctaatactt ctttaagaat tatcccaaca atatcgttag
    28381 acaaaccatt attgaataaa tggagagcca atcgattctg aaaaaatgtt ttctaatttt
    28441 tcggaaataa aagaaagagc ctcctgccat tagaacgaac caaatccatt tcattgctca
    28501 tgaagtaacc acatagctaa aaagaggata aatcaattaa aagatcaaaa gaatgactgc
    28561 actaataaaa taactaaaaa tgtatcttct tacttcatat cttttagcta gtacttagtt
    28621 aaaaatttgc ttcctaagat caagacaaac tgtctatctt catttgatga aatgcggtaa
    28681 aatatagaaa atgaacacta ttggagggaa tttgtaatgg acagcaaaac tagaaaacaa
    28741 ctgcaagaaa agttaaagca acgtacacac ttgctccctt ccgtctttca acagttttta
    28801 gaagaaaatc gttcttccct ttcattaggc agtcgctatg aatacgcaaa agattttcat
    28861 ctgtttactg attatttgag aaaagtattt tctgaagaag tggatgatca gctgattatc
    28921 catttagaaa aacaagatta tcagaatttc ttagctaaaa tctatcgaca tactcgttcg
    28981 ttccaaacta cagcgaacca agaaacggag caattgtttg aaaatagcta ttacgggatt
    29041 tcaaggaagc aatattcatt aaatcatttt ttacgatttt tgtatcaaaa aggactgatt
    29101 gaagaagaga tttctctttt gggtacaagt ttaccggaaa caaccaaagc agctccgcga
    29161 tatatcgatg cagaactttt caaagatttt gagcatttgt ttatcccgat tgaaggcttt
    29221 caaacaagca gagaagctag ctttgaagaa aagaatagac cgaggaacct tgcaattact
    29281 gccattcttc tgtattgcgg attaaagatc catgaagtag tagaacttaa acgtaaagat
    29341 gtatctttga ccaagcagat tcttaatctg aatagaaaag aaaacagact gaataaagta
    29401 ccaataccaa aagaagcgat gccatttctg gagaactatt ttaagttaac agcacaaaat
    29461 acggacgaaa attcttttgt ttttcgttcc tcacatgatc agcaaatttc tcctcggact
    29521 attcgccaaa ttttgagcaa aattacagta tataaaaacg tatcgccaga actatgcaga
    29581 aaaacatatc gttattatgc agaactatat ttagatgatg ctgacgcggt aaattattta
    29641 tgtggtaatc gatacctctc atcccattct tttcaagata tctgggaaaa gatggttgat
    29701 ttttcttatc acgaattagc ggcattcgtt cgggtttctt ccatataaaa caaatgtatg
    29761 atcttttttt cacaataaac tatgttatta tataaaggat tatgttacga ttatcttgaa
    29821 tttgtatatt acttaacaaa agataatgga gtgtgaatga tggagaccat aacgtattcc
    29881 cctttgaact tatttacgaa ttttcaagaa gctgcagcta acttttccga gaccccgatt
    29941 atctttgatg agccactttc agctttccca gaattaggac ttgaaacaac ttacaaaaaa
    30001 tgctgcgaaa gtgtgttgaa acgggcttat caattggctc atcttggagt gaaatccgga
    30061 gacaaagtta ttatttataa gagttccgct tttgacacat accttctagc tgtttctgtg
    30121 tcttaccttg gtgcagtgcc tgtcatgact tcttatcatc taccaacaac aacaatggaa
    30181 gtatttatcg atcgtttaga agaccctttc attttatttg atgatgagac aaaaaagcga
    30241 gtgagagaaa tttcaaatgg aacaaaatca aaacagattc ctattcttta tttaatggaa
    30301 caacctgctt tgtctgtttc tcaatcattt ttagacaaaa atgaaatttc ttatatgacc
    30361 catacttctg gtacaactgg tatccctaaa cttatttgtc attctgctca ttctatggga
    30421 tggcggacga aatggcaaaa aacagttttc acaaaaattt cggaaaagaa attaatcgct
    30481 tttcacatct ctccagtgca ttccagattc aatattggta tctcttcttt gatgtccatg
    30541 ggatttccta tgatgccttt agcaaacgca caaagttcaa aagttgttca tatgttggaa
    30601 gctcaccggc caattgcact agagacccat ccgaataact ttgttcagtg gcgttttact
    30661 gctaaggagc atccagaagc tttttcgggt atccgatact atcactccac ttttgatgct
    30721 ataaacaacc agacaatgaa gacatttttg cgaacgtcga tggcacagga tgcggtattt
    30781 cttcaagtat atggccaaag tgaatgcgga ccaatgattc ttaaggctca tacactagag
    30841 agtttgaaaa caagtgatgc aagagatatg ggcgttggac tggaagacat gacaagcgct
    30901 cggattacag attcagttgg gaatgtccta cctgaaaaca cagatggtca tatacaatta
    30961 ctgtctaaag gacgggcttt gacttattac aaggaagatg cacggttcca ggaaaatgtt
    31021 tatggcgatt ggtgggatag cggagattac ggttttatgg ataagcatgg ccacctattt
    31081 ttgaaagatc ggcaagtgga tttgatcgaa acgatcaata gtacattagc tattgaagac
    31141 tttttattag attcgttaga ttttttggca gaagtagtga ttgtaaggga taaaaatcat
    31201 tctccacaac cgattattgc tttagctcct gataaagaaa tggattggaa tcgatggtgg
    31261 gagcaagtcc atgaacttcc tcgcttgaac gtccctatca tccgtgattt tgatgcaatc
    31321 ccgcgaacag ctacaatgaa agtgcaacgg cttcaaatcg agaaagaatt aaaatcacaa
    31381 aagtcctaac tatttaagga aagaaagatc cattttggtc tttcttttct ttttgttttt
    31441 ttaaattgga tgagataaaa atatgccaat tggctgtttt tcttttttga aaatttcgtt
    31501 atactcttat tcatggagga aaatgttatg aaaagaatct tgacaattgg cggttctgat
    31561 ccatttgctg gtggaggaat ccaaacagat ttaaaaactt ttgagaattt tggtctattc
    31621 ggactaagcg ccttgacttc tataggggca ctagatatta atgagcgatt tatgctggaa
    31681 tctatatctt tggaattgct taaacgacag ttagtttcga ttgataaaat gacttcatta
    31741 gatggtatca aaattgggtt attgaattca agtgaagcaa tcatggttgt tcgagacttc
    31801 ataaaaacaa aacaaaatat cccaatcatt ttagaccctg ttttggcatt caaagaaact
    31861 gaagctgtga tcaatcaatt gtatatttcg cagctcatcg aagaactttt tccacttgtt
    31921 acgatgatta cgcctaattt ggcagaagct gctttacttt ctggtcaagc tcttccctct
    31981 tcgttaacag aaatgatcca tctcgctaaa gaactcactg cttcaggaac aaaaaacatt
    32041 gtgatcaaag gcggcacaag gatggctgga gatgaagctg tggatcttct ctattcaatt
    32101 gatcattatg aggtattttc tcataaaaaa atcgacacta caacagtaaa cggggccggt
    32161 tgtgcctttt cttctgcaat aacagcgaat cttgtgttag gggcagattt taccaaagca
    32221 gtagcagaaa gtaaaaaatt tgttgcccat tgtatttcta atggcgtgct gatgaacgat
    32281 cataccggaa gtgtctggtc tggcggtatt caaaaaggag gaatgagaaa tgaaaactaa
    32341 gcaattaacg atctatgcta tgctgattgc gttgacagtt gccctttcat taacaatttt
    32401 gatccctgta ccggctacga atggatttgt gacattatgc gaggccggga tctataccgc
    32461 tgcttttctt tatggtccaa cgggtggatt agttgttggt gcttccagtg gtctattgat
    32521 cgatttgatt tcaggatatc cgcagtgggc agttttttca ttagtgatcc acgggttaca
    32581 aggatatgtt gctggttctt tcagcaaatc ttctactcgt atgtggggat tagggctttt
    32641 attaggaagc ttagttatga tcatcggcta tggtatcgcc ggttggattt tatatgattg
    32701 gccggctgga gtggcttcta taccaggaaa catcttccaa aatctgattg gaatgggact
    32761 tgcctttcct ataactgcaa gtcttcaacg tattcaagca cggaagcaat attaattgaa
    32821 aaagaaggtt ttagaaaatg aagttgtcag aaaaagaatt aaaagaccaa ttgactgaaa
    32881 tagttaatga catattggct gaggcacact tgaaaaaagg tgatcttttt gttttaggat
    32941 gcagcacaag cgaagtcgtt ggaggacata ttggaaaaaa ttccagtgcg gaagttggtc
    33001 aatggatcat ccgtacgtta aaagagttgt tggatcctaa agaaattgcg ctagctgtcc
    33061 aaggttgtga acatttgaac cgagcattag tagtagaacg aacagtggca gaagcaaaaa
    33121 atttcgaaat tgtctctgtt gttcctgcac tacatgctgg aggtgcttgt tctgttgctg
    33181 cttttgacca gttcaatgat cctgtcgaag tggaacacgt agttggacaa gccggtatcg
    33241 atatcggtga cacatcaatc ggtatgcata tcaagcatgt ccaagtacct gtcagacctc
    33301 gtttgaaaac ccttggacaa gctcacgtga cagcccttcg ctctcgtcct aaatatatcg
    33361 gtggtcctag agcgaattat tgaaatgagt aattgacaga gcaatctgaa aaacttcctc
    33421 gcaaagtcca actaatgaac tttaacgagg aagttttact tgtttgtttt atataaccga
    33481 gcttcataag gtgctagtat gcctttagct tcaaattctc cgctagagga atttgacaag
    33541 agtaatgtcc aggactgatc tgcttctttt ggaagttcat agtcagcaag tgattctgtt
    33601 aagtttacca taataagata ttgttcatct tctaaatatc tttcatagac ataaagttgt
    33661 ggatgttcat gaagatattc tttataagaa ccgtatatca gacctttatt ggtttgtcta
    33721 atgcggatca tgttcttata gaattgcagg accgactctg gttcatattc ttgttgttct
    33781 acattgatcg ttttggtatt tggattagtg atcagccaag gttcatgtgt agaaaaacca
    33841 gcatattgtt ccgaagtcca ttgcatgggt gtcctgctgt tgtctctcgt tgtttcacga
    33901 atgatatcca atgcttcttc tcttgtctta ccttccgcaa gcagcctttt ataaagtctt
    33961 ttcgaatcta ctgcatcaac ttgatcgatc gattcaaagg gcatattcgt cattccgatt
    34021 tcctgtcctt gataaataaa tggcgtacct tgcaaaaaga aatacatcat agcgattgct
    34081 tttgcagaca tagcccaaaa atcgggacga gtatctccaa acactgaaac ggcacgagga
    34141 acatcatggt tttccatata taaagcgttc catccgatac catccaatga agtttgccaa
    34201 gcgcttaatg catgtttcaa tttaaggaca tctaattgcc cttctttttc ttgctgccag
    34261 atatggatat gatcaaattc gaatatcata tcgaaataac cgtctttccc tacccattgt
    34321 ggtccttctt ctgcagtgac accacttgct tctccgacag tcatgatatc gtactcttca
    34381 aaaacatgtt tcaaatcggt caaatgttct tcgattcctg agacattttg aaagggtgag
    34441 aaagggttct ctgtggcttt tactgaatat tcatcttttt ttacatgaga aatcgcatct
    34501 aaacgaaatc catctatccc tttatccaac caccatcgga tcatattgaa tagttcttct
    34561 ttcaatttct cgctttccca atttaagtct ggttgttctt ttgcaaaaac atgcagataa
    34621 tactgtccag tttcatgaga atactcccaa gcagaaccgc cgaaaatcga tgtccaatta
    34681 ttcggttctt tgccatctac cccgtcgacc caaatgtaat aatcgcgata cgggctttct
    34741 ttagattttt tcgattcttc aaaccattga tgctgatccg aactatggtt gatgacaaga
    34801 tccataatca ctttgatccc taattcatgt gcttctttta gcaataaatc aaaatcttcc
    34861 atcgttccga atctctcttc tatatcttga tagtcactta cgtcataacc attatcgaca
    34921 aatggagatt gatagatcgg attgatccag ataaagccga taccaagatc tttcaaataa
    34981 ttaagttttt cacggatccc attgatgtct ccttgaccat cgccattgct atctttgaaa
    35041 ctagcaggat agatttgata gcctactgct tctttccacc atttttgttc ttgtatcata
    35101 tcgtttcact cctttaacgg tccctcttga ttataaccga ttctatttta gaagtatcct
    35161 tgttaccggt aactagaaac gaaaagctca acgaatctgc taagtgcgtt cgttgagctt
    35221 tattttatca tagatagcgg gcaatcagtt gaatcatttg cttgggaaat tcattcaagt
    35281 cagtaatatc tacaaaacga ctttcaccgt agatcgactt gatttcttct ttgtcttggc
    35341 caatagctgc ggagacaaat aggattcctt gacgttcata ttctttcaaa acagactgga
    35401 tatcttcttt tgcttttttg cctgtataat ccggcaacgc ttttggctga ccgtcactaa
    35461 tattaagcaa cagtttggtt gttgcggatt gtctgtttaa tttttctgct gctaaacgaa
    35521 gtgcagcacc atcacgattg ttttgccttg gtttcatagt gactaatttt tcatttaacc
    35581 attgaaatcc gtcttcaaat tctttataag aaaacaaaga agtcttttct cttgacgaac
    35641 ggtctgctgt atctccgtaa atcaacaatg ggatatcgac tttcttagaa aattcggcaa
    35701 tggcaatcgc tgcttttttt gccgcttcga tccgatcatc ccgtatcatt gacccagatt
    35761 catcgatccg tacagctacc gctaaagaag gttgctcatg tggcgggttc tttttgtcaa
    35821 aatttctcaa atcaccatat gctactttgc ttgcattgaa ccgctgacct tcgtattttc
    35881 ctttttggta cgtctctgtt tgttcattat ccagtaactc taaaatttgc cggctaagtg
    35941 attctactat tggcattact tgcatgtgta gctcacgtgc ttccggcgtt tttccttgga
    36001 aagctggtcg gtgaacgatg agaccttctt tttcatgaat cgtttccttc atgatttgtc
    36061 gcgcttcttt attcagttgc ttcttgattt ccttatcatg tgcttccatg tcagaagcag
    36121 acatttcttg agaatcatct cctgtttgtt gttctttttg attttttcct tcgatatcgc
    36181 tactgcgttc tttttgcatt tgaggaggaa tctcgttttt ttctattgtt tcttcttgtt
    36241 tctcttctcc ctcatttggt tcttcagcag acaacgattt cttttcatct aagcgcagaa
    36301 tttcttcagc attttcagtg atgtttcgtt catttgcttc ttcggcgcta atggttcttt
    36361 cttttgtatg ctcagattga ggatgacccc atttttcttt tctcaatatg tcctgaagtt
    36421 ccagtagcaa tccactgtca gacaaagctt gttcaagaat tgccaattca tctgaatcag
    36481 tggataattt atacaaaact tttggataaa tcgactggag taaatcttgt ccttgcttat
    36541 aggtatttgc ccaataaaaa taagaacgca ttcctgctac acctttgatg gcgttagctt
    36601 ttgcagtttc atccaacaaa cggataatct ctgccatctt taagagaagt tcttgttttt
    36661 ggatcatagt tttcgccatc gcacgttctg ccatgacttc taaggcagga agatccattt
    36721 tttccgcatg ttgcatccga tctcttaaag attcatttaa tgggcgattt ccttggtaat
    36781 ttcgatttgt agtgatcaca atgacgcaat ctggatggcg acgaatgatt cctgtcggta
    36841 aattcaacat cccatttggt tcgagcgctg agttaagtgc cacaagaaca gaggcatctc
    36901 ggatgacagt cggctcttga atctctaata aatagccttt ttcaatcgct cgaacgattt
    36961 cagaagggta atagctgtaa tggattgcat ctggataatc agcttcgatc ctttgaacta
    37021 gctctgctaa tttttcttta gcagaaaaag gatcaatgcc gtaatggttc tggatcagtg
    37081 tcagtacagc ttcaagtgta tctgtttggt aaatagcttc tagtaattct tggtcttgtt
    37141 ccttattaga atctactaca ggtaataagg ctccgaaaac atctgatttg tccatatctg
    37201 caaaacaggt cacttttgta tagggaagtt gcagatcagc agatagtgct ttggctaatt
    37261 gtgtcttccc cgacccggca tctccttcca aaagtacgtt actgattttc atttcaggat
    37321 cttgccaatt ccctttgatt tcggaggcga tccgccattc ttctgcactt gtccgatggc
    37381 ttttcggttt cttccagatc atttgctttt ctagccgtga aaaggttcgg ttttctgtta
    37441 gtgagaaatt ctccatgctt ctcttcccct tttgatcatc tctgtctatt aatatcctag
    37501 ctcatctaaa agacgtttta aaatacggaa tcgttcccca atcagttctc cgtctttttg
    37561 tagtgtatcg taatacaaaa tgatgtcttc atcgatcttt ggatttttgg tatctacttc
    37621 taccgtcatt cggttccctt gtaatccaat gatgtctacg actggatttt ctggatcata
    37681 aaatttttca taacgataag catcttggaa gtataaactt ccttgcgcag ctaagatcgc
    37741 taaatctaaa atacgtgtga ttggtaattc ttccgactgt cgtgaccatt tttctccagt
    37801 atgtcgccat accttgcctg agatatcgac ttttccacga tcattccact gagcaaggcc
    37861 cagtgaaagc ccttttgcat ccatatttaa tgcatttctt ccatcaactt tatcatagtc
    37921 ttctacaacg attactggtt tatgttttaa atttgttggt atttccatta ttttaactcc
    37981 tcatcctttt atttttagta aataagtaaa ttagtagttt actcatttac taaactatat
    38041 gcgacattat agaggattga agtgaggatt gcaaagaaaa agagcttcat tgatagaaat
    38101 aaaaacacca tctcgttctt ttacacgctc attagtaaca tgtagaaagt ccaagatgat
    38161 gttggaatat tttggctcta tactttttga tgttggtgaa cttcaccaac atcttttttg
    38221 ta
//
LOCUS       DAYNVV010000022        37665 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.022, whole genome shotgun sequence.
ACCESSION   DAYNVV010000022 DAYNVV010000000
VERSION     DAYNVV010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.022"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            137..1204
                     /gene="rlmN"
                     /locus_tag="ACGXWR_001273"
     CDS             137..1204
                     /gene="rlmN"
                     /locus_tag="ACGXWR_001273"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFK0802856.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            1194..1400
                     /locus_tag="ACGXWR_001274"
     CDS             1194..1400
                     /locus_tag="ACGXWR_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802857.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(1397..2500)
                     /locus_tag="ACGXWR_001275"
     CDS             complement(1397..2500)
                     /locus_tag="ACGXWR_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFK0802858.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            3053..3601
                     /gene="aac(6')"
                     /locus_tag="ACGXWR_001276"
     CDS             3053..3601
                     /gene="aac(6')"
                     /locus_tag="ACGXWR_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFK0802859.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            complement(3849..3968)
                     /locus_tag="ACGXWR_001277"
     CDS             complement(3849..3968)
                     /locus_tag="ACGXWR_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFK0802860.1"
                     /translation="MVFQKPLNNFRYIVYYCHTKIKKNKQKETVTKVLSQSLI"
     gene            4147..5808
                     /locus_tag="ACGXWR_001278"
     CDS             4147..5808
                     /locus_tag="ACGXWR_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFK0802861.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(5878..6225)
                     /locus_tag="ACGXWR_001279"
     CDS             complement(5878..6225)
                     /locus_tag="ACGXWR_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HFK0802862.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            6309..7250
                     /gene="opp3b"
                     /locus_tag="ACGXWR_001280"
     CDS             6309..7250
                     /gene="opp3b"
                     /locus_tag="ACGXWR_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFK0802863.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            7251..8294
                     /locus_tag="ACGXWR_001281"
     CDS             7251..8294
                     /locus_tag="ACGXWR_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0802864.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            8300..9370
                     /locus_tag="ACGXWR_001282"
     CDS             8300..9370
                     /locus_tag="ACGXWR_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802865.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            9360..10313
                     /locus_tag="ACGXWR_001283"
     CDS             9360..10313
                     /locus_tag="ACGXWR_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802866.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            10325..11335
                     /locus_tag="ACGXWR_001284"
     CDS             10325..11335
                     /locus_tag="ACGXWR_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFK0802867.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(11620..12441)
                     /locus_tag="ACGXWR_001285"
     CDS             complement(11620..12441)
                     /locus_tag="ACGXWR_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFK0802868.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(12538..12816)
                     /locus_tag="ACGXWR_001286"
     CDS             complement(12538..12816)
                     /locus_tag="ACGXWR_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802869.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            13084..15093
                     /gene="metG"
                     /locus_tag="ACGXWR_001287"
     CDS             13084..15093
                     /gene="metG"
                     /locus_tag="ACGXWR_001287"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFK0802870.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(15572..16159)
                     /locus_tag="ACGXWR_001288"
     CDS             complement(15572..16159)
                     /locus_tag="ACGXWR_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802871.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            16334..17656
                     /locus_tag="ACGXWR_001289"
     CDS             16334..17656
                     /locus_tag="ACGXWR_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFK0802872.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            17811..18587
                     /locus_tag="ACGXWR_001290"
     CDS             17811..18587
                     /locus_tag="ACGXWR_001290"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFK0802873.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            18580..19149
                     /gene="rnmV"
                     /locus_tag="ACGXWR_001291"
     CDS             18580..19149
                     /gene="rnmV"
                     /locus_tag="ACGXWR_001291"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HFK0802874.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            19142..20026
                     /gene="rsmA"
                     /locus_tag="ACGXWR_001292"
     CDS             19142..20026
                     /gene="rsmA"
                     /locus_tag="ACGXWR_001292"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HFK0802875.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            20477..21106
                     /locus_tag="ACGXWR_001293"
     CDS             20477..21106
                     /locus_tag="ACGXWR_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802876.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(21230..22339)
                     /locus_tag="ACGXWR_001294"
     CDS             complement(21230..22339)
                     /locus_tag="ACGXWR_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802877.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            22548..22970
                     /gene="mgsA"
                     /locus_tag="ACGXWR_001295"
     CDS             22548..22970
                     /gene="mgsA"
                     /locus_tag="ACGXWR_001295"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006007 - glucose catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HFK0802878.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     regulatory      23157..23255
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01831"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="THF riboswitches regulate genes encoding folate
                     transporters and folate metabolism; They are most commonly
                     found in Clostridiales and Lactobacillales; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="tetrahydrofolate"
                     /db_xref="RFAM:RF01831"
     gene            23293..23829
                     /locus_tag="ACGXWR_001296"
     CDS             23293..23829
                     /locus_tag="ACGXWR_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFK0802879.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(23869..25632)
                     /locus_tag="ACGXWR_001297"
     CDS             complement(23869..25632)
                     /locus_tag="ACGXWR_001297"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802880.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(25635..27350)
                     /locus_tag="ACGXWR_001298"
     CDS             complement(25635..27350)
                     /locus_tag="ACGXWR_001298"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802881.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(28129..28353)
                     /locus_tag="ACGXWR_001299"
     CDS             complement(28129..28353)
                     /locus_tag="ACGXWR_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802882.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            28544..31321
                     /locus_tag="ACGXWR_001300"
     CDS             28544..31321
                     /locus_tag="ACGXWR_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFK0802883.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            31402..31821
                     /locus_tag="ACGXWR_001301"
     CDS             31402..31821
                     /locus_tag="ACGXWR_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFK0802884.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            31833..32303
                     /locus_tag="ACGXWR_001302"
     CDS             31833..32303
                     /locus_tag="ACGXWR_001302"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFK0802885.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            32320..33099
                     /locus_tag="ACGXWR_001303"
     CDS             32320..33099
                     /locus_tag="ACGXWR_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFK0802886.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            33086..33907
                     /locus_tag="ACGXWR_001304"
     CDS             33086..33907
                     /locus_tag="ACGXWR_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFK0802887.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            33924..34973
                     /locus_tag="ACGXWR_001305"
     CDS             33924..34973
                     /locus_tag="ACGXWR_001305"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFK0802888.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            34986..35990
                     /locus_tag="ACGXWR_001306"
     CDS             34986..35990
                     /locus_tag="ACGXWR_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFK0802889.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            36623..37642
                     /locus_tag="ACGXWR_001307"
     CDS             36623..37642
                     /locus_tag="ACGXWR_001307"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFK0802890.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT        12299 a         6639 c         7681 g        11046 t
ORIGIN      
        1 taatacggta tgatgtcttg tctttttagt ttttgtgaga ttaaagttct attcgattta
       61 tttgtgaagt attgcattaa ggaaatgaat catgtatagt atgtagcgaa actttgagaa
      121 aaagagggaa aatactttgg aaaaacagtc catttatggc ttgacgaatg aagaattaat
      181 caattggttt atagaaaacg gcgagaaaaa attccgagct gcccaagttt gggaatggtt
      241 gtatcaaaaa cgtgtaagta atttcacaga aatgacgaat ctatcgaaac aattgatcga
      301 aaaattatcg gagcatttta tcatcaatcc tctaaaacag atggtcgtcc aagaagcttc
      361 ggatggtaca gtaaaatatt tgtttgaact ccctgataaa aacatgattg agactgtact
      421 gatgagacaa gaatatggct tgtcagtttg tgtgacgaca caagtaggat gtaatatcgg
      481 ctgtacgttt tgtgcaagcg ggctgctcaa aaagaaccgt gatctgactg ctggagaaat
      541 tgttgcacag atcatgatgg tccaacatta ttttgatgag cgcaatcttg gcgaacgcgt
      601 ttcacatgtc gttgtaatgg ggatcggtga gccatttgat aattacgaca atgtaatgga
      661 ctttttgcat atcatcaatg atgccaaagg attggcaatt ggtgctcggc acattacagt
      721 ttccactagt ggattagcac acaaaatcaa ggaattcgct aataacggct tgcaagtcaa
      781 tctggctatt tccttgcacg cgccgaataa tgaggtgcga acatcgatca tgcggatcaa
      841 ccgaagtttc ccaattgaga aattgatgga agctgtggat gagtatttag agaaaacaaa
      901 ccgtcgaatc acgtttgaat atatcatgtt gaatcaagta aatgatagac cagagcatgc
      961 gcaacaatta gcagatctat taaaagataa gaaaaaatta gcatatgtca acttgattcc
     1021 atataatcca gtcagtgaac atgatcaata ttctcgcagt ccaaaagctg atgtattgag
     1081 attttatgat gtattgaaga aaaacggcgt aaactgtgtg atacgtaaag aacatggtac
     1141 agatattgat gcagcttgcg gacaattgcg aagcaagcaa atgaaaaaaa cagttgccaa
     1201 ataatcgtat cctactcgtt ttttcaatta ccataaaagg agcagttttc ttaattaagg
     1261 aactgttcaa cttaaataag agaaaagatt ctatagcgaa agctataaag ctttttttga
     1321 caagaaaaac cctcatcaag caaagaaatg tcctcaattt gatgacagcc tgcttgatgg
     1381 gggttttagc aattatttaa ctgattttct tatatccttg ctggctttct tgtgtagcat
     1441 gataagtttc tacgtcaaga atggcctgtt taaatttttc tcgggtgatt tcataaggca
     1501 catgtttaat atcatttgtt gccatggctt tatctaagat tgcttctaaa tcggtcgtga
     1561 cattgagatt catgtcggtt aacgatactg gaagttggtt ctttttcata aacacataga
     1621 ttttatcaaa caaatcgaac tgctgatcca tcatcaataa ggtcagtaca ccataactga
     1681 cagatgctcc gtgaaggtat ccctccattt tttctagaac agtcgtaccg taatagaatg
     1741 agtgtgccat agcagaatta tagttattgt taactaaaac agaaaccaat ccggtagtaa
     1801 caatgatatc cgaaacgact tgttcaattg catatgaggg acgatcgtcg gcactatctt
     1861 tcaatgcttg cgtaccataa gtcaagagac gatcaatgca catttttccg atttggattc
     1921 ctaatctatc cgtgtagcct agatcatcgc cacgagcaga aaaagtagat tcgacttctt
     1981 tggataaagc atcgccaata cctgcccata agtatttatc aggtgcttcg gcaataattg
     2041 ctgtatcaat gaaggtgtgt acaggtggtt ttgaaggaaa gaagagtccg tccattacgc
     2101 cttcttcgtt atagatgaca cataccgcag tgacgggcga acagttcgaa ccaatagtgg
     2161 gaaaggtgaa gactggttta gctagttttt caccaatgac ttttacagta tcgcaagcac
     2221 ggccaccacc gactgcaaac aggacgtctg ctttttggac actttcatgc tggatcaact
     2281 gttcaatatt tccataagtt gaattacccc cgtaccagag actggcgaca acctctattt
     2341 cctgtgtcaa agctactttt attttgtttt ctgcctttga aagtgcagtc ttccctccaa
     2401 tcagcactac ttttgtccca tattctttga cgattccatt tgctttttca tacgcatctg
     2461 ttccaatggt ataatttggt aagaaaacac tttgactcat attcatttcc ttctttcttc
     2521 gttgaaacgg gttaaaattt taaagagtga tcgatctgac tgcggctgta gatggagtag
     2581 aggtgaacct aagacaggat aagtgatgaa taaggtggca tgaacacctt gaaatcatca
     2641 ataagtatcc taaaaacgaa caagtacaaa aacattgaaa acgacaataa tgaatttttg
     2701 ttcctcttag tatttctacc gattcccttt gcttttttgt aattatctaa aaattctaaa
     2761 aattaagatt attatatgaa aacaggtttt atttgtcaat tcataattgg ttttttttaa
     2821 agcaaaagat aatctatatc atgatgaaca aacagagttt tttcctccaa ttgatggctt
     2881 tcctgatctt tcctattttg aataaagtgt ttctgtataa tttttttatt ttataagtaa
     2941 gataaataat gaaagaatag agatactgat tggtagctaa agatttttga gcgagaacat
     3001 ttcgtttttt caaaaggact gttagaataa gcaagaacaa gggggaagac gtatgataat
     3061 cagtgaattt gaccgtaata atccagtatt gaaagatcag ctttctgatt tactgagact
     3121 gacttggccg gaagaatatg gagacagctc ggcagaagaa gtagaagaaa tgatgaatcc
     3181 agaacgaatc gcggtagcag cggtagacca agatgagtta gtaggattta ttggtgcaat
     3241 ccctcaatac ggtatcacag gttgggaatt gcatccatta gttgtagaaa gctcccgacg
     3301 aaagaaccaa ataggtactc gattagtcaa ttacttagaa aaagaagtag cttccagagg
     3361 aggaatcacg atttatttag gtacggatga tttagaccat ggaacaacgt taagtcaaac
     3421 ggacctgtat gagcatacat ttgataaagt ggcttccatc cagaaccttc gtgaacatcc
     3481 gtatgaattc tatgaaaaat taggttataa aatcgtaggt gtcttaccaa atgcaaatgg
     3541 ctgggacaaa ccggatattt ggatggcaaa aacgattatt cctcgaccaa attctcaata
     3601 ataaaaagag gttgtgacag aagtaatcag cttcaagaaa taagaaggaa tttacgaaaa
     3661 ttacttcttg aatttttgtg aaattccaac ttatttccga agaagctact tttggaacac
     3721 cgtgtaccag aggttgtgaa aaagtcgctt agtttcgagt agtaagaaaa attttgtgaa
     3781 aatggctttc tacatttttg cataaatttg gcttaatacc gagaaactgg cttttgaaca
     3841 ccgtttattc agataaggga ctgtgacaag acttttgtca cagtttcttt ttgtttattc
     3901 ttttttatct ttgtatggca ataatagaca atataacgaa aattatttaa tggcttttgg
     3961 aagaccatgg aaaaccttgt acaaagctat tttttctgaa aaattccttg aaacctcacg
     4021 aaaaaatcat tattttatga aaaagacaaa aaaaagtgtt gattttttaa taattattca
     4081 ttaaactctt aaacaacttc agaaaatatt aattattctg aaaattccaa taaaggggta
     4141 cgtaaaatga aaaagaaatt tacatttggt ttggttgcgg tatgcggcct tgtacttgct
     4201 ggatgttatg gcggcagttc agccacaagc agtagttcag caaaaagcgg ttcagcagat
     4261 ggaggaggcg tatttaactt agtcgtgcct caagaaatgc ctacagctga cttatcagtt
     4321 gcaacagata caatcagttt tacagcattg aataacgttt atgaaggaat ttaccgtctt
     4381 gatgaagaca gcaaaccaca gccggcagga gctagcgagt tggcagaagt cagtgaagac
     4441 ggattaactt acaaaatcaa attacgagaa gacgcaaaat ggtcaaatgg tgatcctgtt
     4501 acagcagcgg attacgttta tggctggcaa cgaacagtag acccagctac agcttctgaa
     4561 tatgcttacc tgtatgcgcc agttgaaaat gcagaagaca ttacagctgg aaagaaagat
     4621 aaatcagaac tagggatcaa agcagttggt gactatgaat tagaaatcaa attgacgaaa
     4681 caaacaccat atttccaata tctgcttgct ttcccatcat ttttcccaca aaaacaatcc
     4741 gtagtggaag aaaatgggga tgcctatgca tctgcaagtg ataaagctgt ttataatgga
     4801 ccattcacat tagaagattt tgatggacca ggaacagata cagaatggac ttataagaaa
     4861 aatgatcatt actgggacaa agatacagta aaactttctg aaatcaaagt cagtgtagta
     4921 aaagaatctt ctactgcatt gaacttattc aaagatggcc aagcagatga cgtgatcttg
     4981 tctggtgagt tagcacagca aaacgcaaac gatccagctt atacttctgt taaagaagcg
     5041 cggacaagct atatcgaatt caatcaacgt gaaaagaatt caccattcaa caatgtgaac
     5101 ctaagaaaag ctatttctta ttctatcgat cgtgaagctt tagtaaaaca agtactaggt
     5161 gacggatcag ttgtctctac aggattgatc ccatcagata tggtaaaaag tccaacaacg
     5221 aacgaagact ttgcaaaaga agctggaaaa ttagtttctt atgacaaaga taaagcaaaa
     5281 gaatattggg aaaaagcgaa aaaagaattg ggcgttgatt ctttagaatt tgatttgatg
     5341 gcttctgatg atgattcatc gaaaaaagta atcgaatatg ttcaaaactc aatccaagaa
     5401 aacttggatg gcgtaacagt caaaccaaca cctgttccat tctctgtacg tcttgaccgc
     5461 tcaacttcgg gtgattttga cgcagtacta ggcggatggg ctgctgacta tgcagaccca
     5521 agcagcttta ctgatttgtt tgtcacaggt aattcataca accgtggtcg ctggagcaat
     5581 gcagaatatg acgaagcagt taaagcagct tcatcaacag acgctggcga tgaacaagcc
     5641 cgttgggatg atttccaaaa agcaatcaag atcatctctg atgatatggg tgtcgttccg
     5701 gtgtaccaaa aagcagaagg tcacctagtg aatgaaaaaa tcaaaggtat cgttcaccat
     5761 gcggcaggcg cttcatggga ttacaaatgg acatacgttg aagaataatc gttaataccg
     5821 tgagcatgag aaaaaacgag gctgcggcaa atgtcgcaac ctcgttctca tattcactta
     5881 tcctaacaaa gaaaaaagca tgaaaatagc agaaagagca attagtattc cggcaatgat
     5941 cagccaaaag ctgtacatac cgtagctggc agacgagagc gaggaaaatt ctggtttttt
     6001 ctttcggttc cttgttcgtg caagatggac cgatcgctga aaatgatcga agaaacccga
     6061 agaaaagacc cataaaaaac cgccgataat cagaaacggc aatgaccata agaatagatc
     6121 attagataat tgaatgagtg taaaggaatg gttgatgaga ttttttatta aaataaccag
     6181 aatcagtaga aaagctactg cgtaggggat agattttttt ttcatttgat tgctccttta
     6241 tttttggttc attatctaat aatgtagcga aacatctgtc agaagtcaaa agctaggggg
     6301 aaacattagt gaatagttat atcaaatatg tattaaaacg tgtctttttc atgatcatca
     6361 cgctttggtt aattgcaaca atcacctttt tcttgatgca attgctgccg ggcacgccat
     6421 atacgaatca ggaacgtttg agtcctgaaa caatcgagat gctaaataaa caagtcggtt
     6481 tggataaacc agttatcgta caatatggga tttatctttc taatttgctt caaggagatt
     6541 ttggaatttc cttccaattt aaaaaccagc cagtcgcaca tttgttagct ggaagaatcg
     6601 gaccatcctt gcagttaggg ttacaggcaa ttatctttgg aacagtccta gggacgattt
     6661 taggaacgat ctctgccatg aagcaaaata catgggcaga tacatcttct acactcgtag
     6721 cgatattagg tcgttccatt ccaaactttg tatttgctgt tttattacaa tatatctttg
     6781 caatcaaatt acaagttttg ccaatcgcaa aatgggatgg ctttgtgtac acaatcttac
     6841 caacaattgc gttggccatg tcgccgcttg ctgactctgc tcggtttatc cgtacggaaa
     6901 tggtggaagt actgcatagt gattatgtgg aattagcaaa agcaaaagga ttgagccgtt
     6961 gggaaatcgc ctttaaacat ggtcttcgaa atagtttgat tccattgatg actttattag
     7021 gaccgttagc tgtagcattg atgaccggat cactggtggt agaaaatatc tttgctattc
     7081 ctggtatcgg ggaacaattc gttaagtcaa tcacaacaaa tgattatcct acgatcatgg
     7141 ctgtaacgat cctttactca tttatgctga tttttgttat tttgatcgtg gatctattgt
     7201 acggtctagt tgatccaaga attcgtgttt cagaagggag ccgaggataa atggaaatga
     7261 taccaaagcg ttatgaaaca gttgcagata tccctgcgga tgaatttctt ccattacaaa
     7321 aaaataccga agaagaacgt gaacagatta ctgcaccttc tttgaatttt atccaagatt
     7381 catggcgccg tttaaagaaa aacaaagctg ccgttatttc aatggtttta ctattggtca
     7441 tcattttgat ctctgtgatc acaatctttg tttctcctca tgatccaact gcccaaaacg
     7501 tggcttatat caatttgcct cctcgtattc cgggaatcaa tatcgatgga ttgaatggaa
     7561 aagcaatggt tggtggtgaa cttgttgata aatatgctca agcaaacgtc ccttcaaacg
     7621 taaatttctt tttaggaaca gacggtttgg gacgtgatgt attaagccgc ttatttatgg
     7681 gaatgagaat ctcgttgctg atcgcattta ttgctgcatt actagatgta acgattggtg
     7741 tagcttacgg gttggtttct ggtttgttag gcggacgtgt cgataacgtg atgcaacgtt
     7801 ttttggaaat cttatcagga attccaaacc tcgttgtcat gattttgatg ttggtcgttt
     7861 ttgaaccagg aattttttca atcgtggctg ctatggccat cacaaactgg ataccaatgg
     7921 cacgtatcgt tcgtgcacaa acaatgaaat taaaagatca agaatatgtt ttagctggat
     7981 tgacattagg tgaatcaaga atgaaaattg cattcaaaca tattttgccg aatatctcta
     8041 gtgtcattat tattcaaatg atgtttagta ttccatctgc tattttcttc gaagcctttt
     8101 taagctttat cggtttaggt cttacgcctc cgtcagcttc attaggaacg atgttgagcg
     8161 aagggtacaa gacattcctg tatctgcctt atctattatg gattccggca gtaactttat
     8221 cggttatcat gattggcttt aacttacttg ctgatggatt gcgtgatgcc tttgatccta
     8281 aaatgaaaga gtgaagacga tgacgaaaat tttagaagtg aaagacttag aaatctcttt
     8341 tgatacgtat gctggaaagg tacgagcgat tcgcggtgtc aattttcatt tgaataaagg
     8401 agaaacattg gcgatcgttg gggaatctgg aagtggaaaa tcagtgacga ccagaagcat
     8461 catgcgcttg ctgtcaagca acgccaatat agatgctggt caaatcctct ttaaaggtaa
     8521 cgatatcgtt ggaaaatcag aaagagagat gcaaaaaatc cgtggtaaag aaatagcgat
     8581 gattttccaa gatccaatga cctctttaga tccgacgatg cccattggga agcaagtcgc
     8641 tgagtccctt agaaagcata ataaagtttc aaaaaaagag ggacaaaaag ctgcattaga
     8701 attgcttaaa ttagttggaa tacccgaagc tgagaaacgt atcaacagtt atccgcatca
     8761 gttctcagga ggtcagcgtc aacggatcgt gatcgcgatt gcactggtat gttatccgga
     8821 aatcctgatt gctgatgaac ctacaacagc gcttgatgtg actattcaag cacagatttt
     8881 ggagctgctg aaagaaattc agacaaaaat cgatacatca attatcttta tcactcatga
     8941 ccttggtgta gtagcgaatg tcgctgatcg tgtcgctgtc atgtatggag gaagaatcgt
     9001 tgaagttgga acatcggaag aaattttcta caacccgcaa catccctata cttggggact
     9061 gcttggttca atgccgacat tagatagtgc gaacgatcga ttgtatgcta ttcctggttc
     9121 tccaccggat ttattgaacc cgccaaaagg agacgcattc tatccaagaa atgaattcgc
     9181 gatgaaaatc gatgcagaac aagaaccacc attttttgaa ctatcaaaaa cacacaaggc
     9241 agcaacttgg ctacttgctc cgcaggcacc caaagtgaca ccgccagaag aaatccaacg
     9301 tcgctgggct atctttaaag agaaacaaaa acatacttac ggtcaaggag gaattgctga
     9361 tgccaaataa actacttgaa gttaaaggat tgaaacagta tttcaatgta ggaaaaaaga
     9421 atgaagtaca tgctgtaaat gacatcagct ttcacattta tgaaggagaa acattcggtt
     9481 tagttggaga atctggaagc ggaaaatcca ctactggccg tacgatcatt cgcttgaatg
     9541 aacctactga tggtgagata ttattcgacg gtcaagatat aacgaagatc aaagataaaa
     9601 aaggtttgac gaaattccgg catgatgttc agatgatctt tcaagatcca tacgcttcgt
     9661 tgaatcctcg tatgaaagtc agagatatca ttgccgaagg aattgatgtt aatggactag
     9721 ctaaatcatc tgaagagcgt gcaaaaaaag tcgatgatct attgagaact gttggattga
     9781 atccaagcca cggtactcgt tatcctcatg aattttcagg tgggcaacgc cagcgtattg
     9841 gtattgcacg agcattggca gtaaaaccgc gttttatcat ttgtgatgaa ccaatttctg
     9901 cactagatgt gtcgatccaa gcccaagtgg tcaatttgtt gcaagatctc caaaaagaac
     9961 atcaattgac ctatctattt attgcacatg atttgtcgat ggttaaacat attagtgacc
    10021 gaatcggtgt aatgcataac ggcttgttat tagagatggg aacaagtgat gaaatctata
    10081 atcacggtgt tcatccttat acagaaagtt tgttatctgc tattcctcta ccagatccag
    10141 accatgagag aaaacgcaga agaatcaaat atcaacctga accagatgac ggacaagtac
    10201 gtcaacttcg tgaaatcgca ccagaacatt ttgtctatgc aactgagcag gaagtcccat
    10261 attacgcaaa aaaactaaaa cgacaaaagg aatctcttct ggttgctaac taggagggac
    10321 atagatgcta aaagctttta aattccgtat gtatccgaca gaagaacaaa aacagcaatt
    10381 gattcgtact tttggatgtg ctcgatttac ctataaccat ttgctgaaaa agcggcagaa
    10441 aagttggcaa caaacaggag tagccaattt ttcgctcaca cccgctacat taaaaaaaga
    10501 atacccattc ttaaaagaag tagacagtct tgctttagca aatgcacagc ttaatttgga
    10561 tcgggctttt cgcaattatt tcaagggacg tgccagcttc ccaaagctta aaacgaaaaa
    10621 aagtatgtgg caatcttata cgaccaacaa ccaaacccgt acgatctatc tggaaaatgg
    10681 ctacttaaag ttaccaaaac aaaaagaact aatcaagata aatcagcatc ggccagttga
    10741 aggatcgatt cgctccgcta cgatttctgc tcgatataat gaagaatttt atgtcgcact
    10801 actttgtgat gtttcgccag taaaaaaaga atctttagct aaatggatcg ggatcgccta
    10861 tcatccgaag acattgatcc aaacatctcg acctctagaa gtaactttac caaaatttca
    10921 ccagacagaa gaaaagctgc aacatgcaca gcggaaattg aatgtgaaag tccgctccgc
    10981 tcaccataga aagatcaggt tagatcaggc aagcaattat cagaaacaaa agagaaaagt
    11041 aatggatctt tatctgaaac aaaagaacca gcgagaagat tatcttgaac aattatctgg
    11101 gaaattggtc aaacaatatg actacttatt tgtagaatct tttccaaaag aagaggcaca
    11161 tgctgatttt tctattcacg actggcataa attaataaca aaattgcgtt ataagtccca
    11221 atggtataat aaaaaatttc ttttgatcaa taccgacgga gcagaagaaa gcaattccgt
    11281 aagaaagagc caagtagtag aaaaaatggg cagacattcg gttatcaagg gataaaaaat
    11341 gaatgaaact gataggagcg ttagggttag ccttgttaat aaaaagtctt aatgactttt
    11401 gtttctagga atttttcttt tgaagaaaag ctcactaatt atgacaaacc aataaaacaa
    11461 tagcagaaaa agttcgtacg agctttttct gctattgtta attttttatt cagaaagttt
    11521 acgaatacat caaaattctg aaacaaaaaa cgtaactcac aaagagttgt ttttgcgttt
    11581 tttcttgaat gattaggtct gaatcttttg ctcacaacct tattcatggt gccccggctt
    11641 gagctgatag atttttgaag gacggccgat tcctacagga cgttcaccga tctcatcgaa
    11701 atattggagc atagctttct taaaattgga atgatcgatc gttttataat cgatccctaa
    11761 gaatttagca aatacttttc gagcttccgt aatcgtgaaa tctttaccta aaacttgtag
    11821 aacttgcggc tcgtgttcca ttttattgac tacacggttg aatgctttca agatgatttg
    11881 actatggtca aaagccaaag tatctttgcc agaagactct ccagtgacta aatcaagcga
    11941 gatagccact tctccgctag ataaatggat cttgttacta tgacgttcta gtgtgaacca
    12001 gcgtacttcc ttggcatcat ctccggcgat tagcggttct tctccaataa aggctaagta
    12061 gctgactgtg acgacccagc ctcgcggatc tcgattaggc gtactgaatg tatgcagttg
    12121 ctcaatattt tcttttgaaa taaccacacc agtttcttcc tttgtttctc ttaagacgct
    12181 ttctccagtt gactcatcct tttggacaaa gccaccaggc aatgcccatg aatttcgata
    12241 aggatgccct tttctttgga tcaacaaaac tttcagctga tcttcttctt tgttatagca
    12301 catcagtacg atatcgacag tcaaagaggg cttgtcatat tctggacgtt cctgtttttg
    12361 ataccagtta agaaattctt cttcacttgc tttatgttca taatataatt tttcttcttc
    12421 tttagaagca aaacggttca tctgaccacc tccattgaca gtaaaagtac tttttacctt
    12481 attgtagcag actctgaaaa aaaaccaagg atttacttga aaaatctagg ttatcattta
    12541 aatatgaaaa ataaatggaa gtatgagatt gaataaaaag aaaagcagat aaaacggcaa
    12601 tactttatac cgctcttcac gaatggcaaa gaagccacaa ataacgatat atacgtcaat
    12661 gataaaacgc aaaatccaag ctgctgtcat aaaactgttc aaatgcccat ggaggttaaa
    12721 ataaccatac atacgaatat aaaaatagct gaatattaaa tgtgctaatg aaagaaaagc
    12781 aatactaagt gtaaaaaaaa gatgtttctt ctgcatgatt gttccagtcc cttactaaga
    12841 tagatagtct ttattatacc acgtgtgagg ggagaaataa aaagccgttt tttagtagat
    12901 atgaaacaaa acaaaaaccc gcatttattc aacctattca tccttttaaa ggatagattg
    12961 aacgtagata gaagtcgttt atccagtctt tttcattttg aaaaaaagct aacagcatgc
    13021 tttttttatg gtatactagc aaggaaacga attcgcatca tgcgataaag gaggaagagc
    13081 cccgtggcag aaaaggaaac tttttatatc actacgccaa tctattatcc aagcggcaaa
    13141 cttcatatcg gcaactcgta tactacgatt gcatgtgacg caattgctcg ttataaacgg
    13201 ttgatgggct ttgatgtgtt ttatctcact ggagtggatg aacatggtca aaaaatcgaa
    13261 acaaaagcag aagaactagg tgtaaaaccg caagaatatg tagataaaat ggcggctgat
    13321 gtcaagaaat tatggaaaac gcttgatatc agttatgata aattcattcg cacgacagat
    13381 gattaccata aagcagctgt tcaaaaaata tttgatcgtt tattagaaca gggagatatt
    13441 tacttaggtg aatatgaagg ctggtactct gtttctgacg aagaattctt tacagaaaca
    13501 caacttgcag aagtgtacaa agatgacgaa ggtaacgtga tcggtggtaa agcgccaagt
    13561 ggacacgaag tagaattggt aaaagaagaa tcatacttct tccgcatgag caaatacgca
    13621 gaccgtctat tggaatacta tgaagaacat cccgaattca tccagccaga atctcgtaaa
    13681 aacgaaatga tcaacaactt tatcaaacca ggattagagg atcttgcagt ttcacgaaca
    13741 acttttactt ggggagtacc agtcaagagt gatccgaaac atgtggtgta tgtatggatc
    13801 gatgcattat ccaattatat tactgcacta ggatatggct ccgaagatga aagtctattc
    13861 gaaaaatact ggcctgcaga tgttcagatg gtcggtaaag aaatcgttcg ctttcatacg
    13921 atctattggc caatcatgct gatggccctt gatttgcctc tacctaaaaa agtatttggg
    13981 catggctggc tattgatgaa agacggaaaa atgtctaaat caaaaggaaa tgtcgtttat
    14041 cctgaaatgc ttgtggaacg ttatggttta gatgcactcc gttattattt gcttcgtgct
    14101 gttccgtttg ggtcagatgg tgtctttacg ccagaagatt ttgtttcccg tgtcaattat
    14161 gatctggcaa atgatctagg gaacttattg aatcgaacga ttgctatgat caacaaatat
    14221 tgtgatggac tcgttcctga ctatgcctca cttgtcactc catttgatag tgaactgtct
    14281 acgacggctg ctaacgttgt cggacgttac catgatgcaa tggaaaaaat ggaattcaat
    14341 acagcattgg ctgaaatctg ggtgctgatt tctcgtgcaa acaaatacat tgatgaaaca
    14401 gaaccatggg tattagcaaa agacgaagaa aagaaagctg aattgaatag tgtcatgatc
    14461 catttagctg aatctttgcg tatcgcagcg atattacttc agccaatcat gacagaaacg
    14521 ccagagaaga tcttcaatca actaggattg gactctgaaa caatgaatct tgaaggatta
    14581 cactttggcg aatttccttc aggaacaaaa gtagttgcaa aaggtacacc aatcttccca
    14641 cgtttagata tggaagaaga agttgctttt attcaagaaa aaatgtctga aggtactcaa
    14701 acaaacgaag atacagtcaa atgggatcca gaagaaacag aacttgtttc aacgaaagaa
    14761 aaacaaatca aatttgatgt atttgaaaaa gtagaactaa aagtagcaga agtcatcaac
    14821 tgtcaaaaag tagaaggggc agataagttg ctgcaattcc gactagatgc tggagacagc
    14881 caagaccgtc aaatcttgtc aggaatcgct gaattttatc ctgatccaag cgaattgatc
    14941 gggaaaaaag tcgtcattgt agcaaatctg aaaccacgaa agatgcgtgg acaaatcagt
    15001 caaggaatga tcctttctgc agaagcacca gatggctctt tacaagtaat cgaagcacca
    15061 aaatccatgc caaatggctc agaaatcgca tagaaattca aagggggtat gacactagtt
    15121 gtgtcatacc ccctttttcc gaaatttgag aagcaatttt cgtaaattcc ttcttattac
    15181 ttgaagccaa tcatataata cagaaacaga gaactatcca aaataaatcc tagaaaaaga
    15241 agtacgagct tcgctgattt ttgttaattt agaataatac taataggaat cgtaaaaaca
    15301 gaaaaaaagc ataatgataa agggtcgggc agattttaat tgattcatct ggtactcttt
    15361 tttattgtcc ttacattcat aaagtttgaa tgcaatgact ttattacatc tatatttata
    15421 tctaacagta gcgttgatgt gttaattata agttctatca ctttatgttc aattagtttg
    15481 tgctcttata tgtgtgattg aaaatataga taaaaaaaca atcatcggct ttgacttcga
    15541 tgattgtttt ctttattttg taaaaatcct atcacttgat tttatggtaa ccttttattt
    15601 ttgtcttcaa acggcttggt aagagagcag taagcagtgc aaatgggatc gaaaagacat
    15661 accagaaaat cgtacgtccg ataccataat gttgatagag ctttgtcaac atcacgtgta
    15721 acaagatcaa ccctaaaagc aaggagccag ctataaacca atgattatcc caatgcatga
    15781 cttcactaag tgccatcact ccaaaaggat agaaataaaa atagatcccg actaaggtca
    15841 tccgccagtt ctttgtaaat gttccgatat tcaataaaaa gaaaatcgct gaaagcaaaa
    15901 taccgatagg cggaaaaagc ccaaccaaaa aggaatacaa catcccccac aagatcatca
    15961 caggaccttt gatcaatgca acgattgcga tgaacaaagt cagcaatatt agtttttgtg
    16021 ataacgttgc aacagtcatt aatccaaata aaattaatgt gaaccaatgc caatgggact
    16081 gctgttgttc tttacgggaa aaatcgaccc ggttggataa ataatctgct aatttcggat
    16141 aagaacgctt aaaatccata aactgttcct ccttcgtgga aaaggtaggt ttagtatacg
    16201 aaaaataaaa aagaaataca tccgtcttaa gagggagttt ttcactgaaa gtggagaaaa
    16261 aagaatggta aattaaaata ttctcagtta tactgaaaat tataccaaat ttcaaagaag
    16321 aaagaggatg ggaatgaaag gcaaactaaa acgagaaatc aatctgtttg gcgcattagc
    16381 taccgttatg ggaaccgtga tcggtgcagg cgtcttcttc aaaactgctg ctgttactgc
    16441 tagtactcag tctacaagtt tgacattgct agcttggctt ttgggtggtt tcttaacgat
    16501 ctgtgctgga ttgacagtgg ctgaattagc tacagcaatc ccggaaactg gtggagctgt
    16561 aaaatatatt gaagctgcgt atggaaaatt gcccagcttt ttattaggat gggcgcaaag
    16621 cttgatttac tttcctgcta atattgctgc attatcgatt atctttgcga cacaattgac
    16681 gaacttatta caattatcta ccgattatct tttgttgatt gcagtgatca ccgctgtttc
    16741 tgtgacaggg ttgaatttgt tagggacaaa agtcggtgct tctgtacaat cagtgacgtt
    16801 gattgttaaa ttaataccaa ttgctgtgat tgtcatatgg ggattattga ccccaggaca
    16861 aggaactgtc cagttatttc caatcgaagc tggaaaagat gttacttttg tcgaaggatt
    16921 gagcagtgcg ttgttagcaa cgttgtttgc ttatgacggc tggttaggtg tcggtgcaat
    16981 ggcaggggaa atgaaacggc cggaaaaaga tttgcctaaa gcaattattc ttggtttgag
    17041 ttttgtaaca gtcgtttatc tattgatcaa ttttgttttt ttgaaaactt tgccgattga
    17101 tcatcttgcc ggtaatttga atgcagcttc tgaagcatca gacgtcattt ttggaggaat
    17161 cggtggaaag ctggtcacta ttgggatctt gatctcggta tacggtgcat tgaacggtta
    17221 tacactaact gggatccgcg tgccttatgc gatggcttta gaagacgagc tacctttcag
    17281 taaacagctg acaaagcttt caaagaagtt tacggttcct tatgttcctg cggttttcca
    17341 gttagcagta gcttgtatta tgatgagcct tggttctttc gactttttaa cagacatgtt
    17401 gatttttgtg atgtggctat tcagtttact gatttttatc ggtgtcttta ttttaagaaa
    17461 aaaagcgccg gaattgccac gtccatataa agtaccactt tatccaatcg ttccgattat
    17521 tgcgattctc ggtgctattt tcattttagg tatgacgatg atgacgcaaa cgaaattagc
    17581 attgatcggt ataggtgtta ccttgatagg tatcccagtc tattatcaaa aaaagaaaaa
    17641 acgctcagaa gagtaaaata tttcaacaac agacagaaaa agtacgaact aggtcctcta
    17701 gatcttcgtg ctttttctat ttcaataaaa caagttcttc tattttgatt tttgctactt
    17761 ctgcaagtag tgcttatgtg ctaaagtaag aatgaaaagg agagataaac atgatatttg
    17821 attctcatac ccatttaaat gctgaacagt tcaatgaaga tattccagaa acgattcagc
    17881 gagcacaaga aatgggggta acgaaaatgg cggtcgtggg cttcgatacg ccaacgattg
    17941 aaaagtcttt gcaattaagc catgactatc caaatatata cagtattatc ggctggcatc
    18001 cgacagaggc tggcagttat acgaaagaaa tcgaaaataa attacaagaa caattgactt
    18061 taccaaaggt tgtagcatta ggggaaattg gcttggatta tcattggatg gaagacccga
    18121 aagaagtcca agataaagta tttcgcagac agattgctat cgcaaaagaa atgaacctac
    18181 caatcagtat tcatactaga gaagcacttg aagacacgta tcaaatccta aaagaagaag
    18241 atgttcgaga tatcggtgga atcatgcata gtttcagtgg tgattatgaa tgggcaaaac
    18301 gatttcttga cttagggatg catatttcat ttagcggtgt cgtcactttc aaaaaagcat
    18361 tagacgtcca agaggctgca gcaaatgtac caatcgaacg attacttgtg gaaacagatg
    18421 ccccttatct ggcaccagtt ccttttagag gaaagcgaaa tgaaccaggc tatactcgtt
    18481 atacagtaga aaagattgct gaacttcgga atcttccgac agaagaagtg gctgcccaaa
    18541 catggacaaa tgcgcaccga ttatttggtc taagcgaaca tggataagat gaagatccaa
    18601 gagattatag tcgttgaagg aaaagacgat acaagaaggc tgcgggaagt agttgatgca
    18661 gatacgatag aaacaatagg gtctgcaatc aatgaagaga tcctgatgca aattgaacat
    18721 gcccaagaga ctcgtggagt gatcgttttt accgatcctg atttttcagg agaaaaaata
    18781 agaaaaatca ttatggaagc tgttcctcag gcaaaacatg cttttttgcc gcgcacacaa
    18841 gctaaaccaa agaaaaaggg aagccttggt gtcgagcatg caagtgatgc tgctatttta
    18901 gaagcattga aaaaggtcgt gacgccagac atttcccaaa cggctgtttc tgaaatcact
    18961 agacaagacc ttttagacta tggtttaata gctggggcac aagcaaaaga aaaacgagaa
    19021 aaactaggtg acgagttgcg catcggttac acgaacggca aacaattgga aaaacgtttg
    19081 aagatgtttc gtattacgcc gaaagaactc gcccaagcaa tgaaaatagt ggaggaacaa
    19141 catgagtgaa tatcgtgaaa ttgcgacacc ctctagaaca aaagagattt tattgaaaca
    19201 tggtttttca tttaaaaaaa gtttaggaca aaattttctg actgaaccaa atattttaag
    19261 gaaaatcgta gaaactgcgc aaatagatga acatacgaac gtgatcgaag ttggaccagg
    19321 aatcggtgca ttgacggaac aattagccaa gcatgcaaaa caagtcgtag catttgagat
    19381 cgatgatcgt ttgatccctg tattggctga tacgatgcaa ccctatgaca atgtgactat
    19441 tgtacatcaa gatattttaa agaccgattt gtcaacagct gttagagaaa catttcatga
    19501 ggagcttccg ttaaaagtcg tagcgaattt accttactat attacgacac cgatcatgat
    19561 gcattttctt gaatcagatt tggttgtgga tgaactagtc gtcatgatgc aaaaagaagt
    19621 agctgatcgt atctctgctg aaccaggaac gaaagcttat ggttcattat cgattgctgt
    19681 tcaatattat atggaagcca gtttagcatt catcgtacca aaaacagtat ttgtccctca
    19741 gccaaatgta gattcagcga ttttgaaact gacaagaaga gatataccgg cagtcgaagt
    19801 gacagacgaa aaagcatttt tccgattgac aaaagcggca tttcagcaaa gaagaaaaac
    19861 gctttggaat aacttgcagc attcgtatgg caaagatgac cagacaaaag catggttagc
    19921 aaaaagcttg gaaacagctg gaatcgatcc aaaacgtcgt ggggagactt tgtcattaca
    19981 agaattcgcc gcattaagca atgcgatgtc agaaaatatg cagtaaaaaa agaggttgtg
    20041 acagaagttg tgaaaaagct gtcctgcatc aagtaataag aacagccaaa caaaaatagt
    20101 tcctcatgtt tttcgtttgt ttgggcttat taccgcagat gcaagctttt gaacaccgtt
    20161 taagaaagag gttgtgggcc tgccgtttaa ctctaagtca caaggaacaa tttcaaaaaa
    20221 cagcttctca tgtttttgag ttagttggtc ttattacttg atgcaagctt ttgaccacta
    20281 ttatgccgaa caaggagatg tgacacaaat tttgtcacat ctcctatttt tgtttcttga
    20341 tcaaaaaatt cttatacttg atactcacac tcattttgta tggatttaga aaagaatatg
    20401 tgtcttgaca gttattagta agtgagttat actaagtcga catttatgtg tcaagacata
    20461 ttaggagaga gaaaaaatga gaaaaaattc agttcgaaaa ctaacgattt ctgctttatt
    20521 gattgggatg ggggtcatta tcccaatggt catgcctaaa atcatgattc caccagcttc
    20581 ctttactttg gcgtctcatg tgccattatt tattgcgatg ttttttacac caggagttgc
    20641 agtggctgtt gcgctaggta cgacatttgg tttcttttta acaacgccgg ttatcatcgc
    20701 attgcgagca ttgtcacatc ttgtgtttgc gttgattggg gcttggtact tgcaaaagca
    20761 tccgagtatc gttttaaaaa atggacagtt tacttttgct aattggcgtt tccaagggtt
    20821 caattttgtg atcggtgtga ttcattcttt agcagaaatg ctagtagtca gcatctttta
    20881 ctttattggt aatatgcctg aaacatatta ttctcaagga tatttttata cagtattcat
    20941 cttgatgggg attggtgggc ttatccacag tttagttgat tataatattg cttattttat
    21001 agcaggaaca ctcagcaaat attttgatat ccccgtattt acggcagcaa aaaaagaaaa
    21061 tcggaaagag tcgattcaag ggtacgcgaa gaaaacgaca tattagacat gatctctcaa
    21121 aaaaaaaact ctcatctagt aatggataat aaatcctcta agatgagagt tttttgtcct
    21181 aaaaagagct gcaccaacat cttctggcac agctctaaca gggggcaatt tatggaagtt
    21241 tgatgacttg ttctgtttct ttatcaaaga agtggccttt gctgatgttg aaggcaaggt
    21301 cgactatttc gcctggttta tggaaatctc ttgcatctac ttttgagatg aactcagtag
    21361 aaccagtttt tgtgtaaagc atcgtttcag ctccaagtaa ttcggaaacg acaacttctg
    21421 atttcactac ggcttcaggt gaagcttcaa gggctacttg ttcactgtgg atgtcttctg
    21481 gacgaatacc gaagataact tcttttcctt cataaccttt ttcaactaat actttgtttt
    21541 ttccttcagg aatacgaagc ttaagcccat gtccatctgt gataacacca tttttcaatg
    21601 tcacattaaa gaagttcatg gcaggagatc caataaagcc ggcaacgaac atattgacgg
    21661 gtgtatcata aacttctttc ggtgtaccga tttgttggat aaatccgtct ttcatgataa
    21721 cgattcggtc agccatagtc attgcttctg tctgatcgtg agtaacatag atggtcgttg
    21781 tttcaagacg ctggtgaagt ttggcaatct cagcacgcat ggctacacgt aatttagcat
    21841 ctaaatttga taatggctca tccattaaga agacttttgc atcccgaacg attgcccgtc
    21901 ccaatgccac acgttggcgt tgtccaccag ataaagcagc tggttttcgt ttcaagtatt
    21961 ctgtcagacc taagatctct gctgcattgt ccacacgttt tttgatgtct gctttatcat
    22021 atttacgtaa tttcaagcca aaagccatat tatcaaaaac agtcatatga ggatacaatg
    22081 cgtagttttg gaaaaccatg gcaatatcac ggtctttagg tgccacgtca ttcatgactt
    22141 ttccgccgat atttagttct ccttcagaga tatcttccag tcccgcgatc attcgcaaag
    22201 tagttgactt tccacaaccg gaaggaccaa caaaaacgat aaattcacgg tctttgattg
    22261 atagattaaa atcagttaca gaataatttt ctgcattgtc atatttttta tatacgtttt
    22321 tcagagccat ttctaccata atacgttcca cactttcttt tttagtttta ttaactattt
    22381 aaagtataaa tgaaagcgtt aactaacttc aatgtcatgt tgaacaagaa ttttttcttt
    22441 tttttgtcaa tgtgctagtt ttaagcttta ataaatatcc ataagaaata aaaactgata
    22501 cactggagta aataagtatg ttaacaatat caaaaggagt gtctcttatg aaaatcgctt
    22561 tgatcgctca tgaccgaaaa aaacctatga tggtgaaatt agcaacagcg tataaaacaa
    22621 tattggaaaa acatgaactt tttgctaccg ggacgactgg gcagaggatc acggaagcaa
    22681 ccggcttgcc gatccatcgg tttaaatccg gaccgttagg cggggatcag caaattggag
    22741 ccatgatttc ggaggatcag ttagatttgg tgatttttct tcgagacccg ctggctgcac
    22801 agccccatga accagatgta acagcactta tccgtttatc tgatgtctat gagattccgt
    22861 tagctacgaa tatcggaaca gctgaggtgc tactaagagg actggaagcc ggcttcctag
    22921 attttcgaag aatcgtccat gaaatagaca agcatccact ttcattttga tggataagcg
    22981 tatggaaaaa taacgtttaa tgttcgccta tatgtagcta taaaagctaa acaaactgat
    23041 aatatgcgat ataatacgaa cgtattggat aatataaaca ataatattag tttttcgtat
    23101 ttgcagtaaa tgtgaaaata tgctatagtt tctgtgggaa aagatcccaa aaataataca
    23161 gagtagaaaa taaagcgtta agtgctaaga ggatgggatg ttgcctcttg gacgaaggac
    23221 gtaatgttcg cggttttatt ttcgcattcg ctgcatgata cgatgtagca gctcttaaag
    23281 gagatgctaa aaatgaagaa acaccggtta gacgcacgta tgattgctat tatgggctta
    23341 ttgattgcat tgatggtcac tttgtcccga ctggtagcaa tcgagacccc atttattaaa
    23401 atcagtgtca catttattcc acaagtgatc atgggcattc tttttggtcc tttttggtca
    23461 gggataggcg cagttttagc tgatttagta ggaatggccc tcttctcgaa atctgcattc
    23521 tttattggat ttacattgaa tgcatttatt gaaggagcaa tctacggatt ctttttctat
    23581 cgaaaagaga tcacttggaa aaatgccatt ctggctacgc ttagtgtcac gctgatcatc
    23641 aacttatttt tgacaccatt atggcttgcg ttgatgtacc atgtgccatt gttcagctgg
    23701 gtcgtttggg cgccccgcct gttaaaaaca gtaatatggt taccgattca atcaattgcc
    23761 atttattacg taggacgtag tattccttac aaaaaaattt taagaagttt agcgatccac
    23821 gctaaataaa aaacaagcag tcttcccatc ccagaagact gcttgttttt attgtgctgt
    23881 gaattgtgct tgatagagcc gtcggtaata accatctttt tgaagcagct catcatgggt
    23941 gcccatttcg acaatagctc cctgatccat cactaatatc tggtccgcat ttttgattgt
    24001 ggacaggcga tgggcaatca caaaactggt ttttccttcc atcattgcta agaaggcttg
    24061 ttggattttt ttctctgtca atgtatcgac tgagctggta gcttcatcta agatcaacat
    24121 agggggatta ctgatcatcg ttcgagcaat cgtcaacagt tggcgttgtc catctgatat
    24181 ctttaaccct tgaccgccaa tcttagtatc taatttttcc ggcaaacgtt ctacaaattc
    24241 atacatataa gaggctttta gggcatcatt gatttctgcg tcacttgctt ccggattccc
    24301 aaaacgaaga ttttctcgca atgtactgtc aaatagccaa gtatcttgta acaccattcc
    24361 aaaactttta cgtaatgtat cacgttggat agagcggatg tcatggtcat cgactgtaat
    24421 tgttcctttt gttgtgtcat aaaaacgcat cagcaaatta acaagtgtgg attttccggc
    24481 ccctgttttt cctactatag caatggtttg acctggataa gcagtaaaat tgaaatcttc
    24541 gatcaaacgc tgcttggggt cataagaaaa agaaacatga tcaaaagaga cttttccttt
    24601 gatatttttg ggttccaagg cataggcatc tggcaaatca ggcttttctt ctggctgatc
    24661 gatcaaatca aatgctcgtt ctagaccaga aaaagcggtt tgcagttgtg tcgtgattcc
    24721 agaaagttcg ataaatggtt tagaaaactg acttgagtag atcgtaaagc tggaaatcac
    24781 accaacagtg attgacgaac cactctttaa tgccaatagg ccgccaacta aaccaatcga
    24841 taaataagca aggtgatcta caaaacgaga agacgggttt gtcaaggaag aagaaaattg
    24901 tgcccgttgt cctttttcat atagatcagc atttagcagt tcaaattgct gttgactagc
    24961 ttcttcttgc tgaaaagctt tcacgatttt ctggttaccg attcgttcgg tcacaaagcc
    25021 cgagatatcc ccaataatcc tttgctgtct atcgaaattt gtttgtgaag cacgagcaac
    25081 gatccaactc acaaggaaaa taattggtgt agaacaaaga acgaccaatg tcagaagtgg
    25141 acttagacgc atcataaaaa taaacgaaag aatgatgatt gccactccag aaaataattg
    25201 attgaaggcc gcagaaattg caatggaaat attgtccata tcatttgtaa atcgactgac
    25261 gatatttccg tgggagtttt gatcataata acgaagtggc aatcgattca gatgagcaaa
    25321 tgcatctttt cttaattttg caacggataa gtaagctaac cgattgctta acacttggat
    25381 gagccattga ctgactacgt tgattaaaac gataccaccg aatagaataa gtaaatggaa
    25441 cagtcgattg aagcggacct gtccttctcc aatcatttga tcgatacttt gaccaatttg
    25501 taacgtcatc acaactgttg caatcccatt gatgattcct agtatcacag ctagccaaat
    25561 gtcttttgca taggcagtaa ggtaaggaat gaatcggcgg agcgtctgca aggataattt
    25621 ttttactttc ataactattc ttcctcctgt gatgcgacga tttcctgata ttctgctgat
    25681 tgagcaagta attcttcatg ggtaccctga gcagcaatct taccttgatc catcactaag
    25741 atatgatgtg cttcttgaat agagcggaca cgttgggaga taataatcac tgtactgcca
    25801 agataagtct gtagcgcctt acgcaaatcc aagtctgttt gataatccaa cgcacttaaa
    25861 gagtcatcta aaatcagtaa tgctggcttg gcaatcaaag ctcttgcaat cgtcagtcgc
    25921 tgtttttgtc cgccagagaa atttttccca ttttccatga cttttgtatc taaaccattt
    25981 ggaagctgac ggacaaattc ttctgcctga gcgattttca gagcttccca acattctttt
    26041 tctgtggcgt ctttcttacc ccattgaagg ttttcacgaa tagtcccggt aaatagtaca
    26101 gaagtttggg gaacaagagc aatttgctga cggagatgat ccagctgcca agaacgaaca
    26161 tccattccgt ccattataac tgtaccggaa ctgacatcat agaaacgcgg aatcaattgt
    26221 gtcaaagtcg ttttcccgct tccggttgga ccaatgattc caaggactgt atttcgcttc
    26281 agctgaaatg taatattttg gagagaaaga ccagaatcag gagtataacg gaagtcaaca
    26341 tggtcaaaag cgataattgc ttcagaagaa aaatcgggag tagtactgac ctcagcttca
    26401 agaatcgaat tttctgtgtc tagcacctct ttcacccgat ttcctgaagc ttcggcacgt
    26461 gtgaagatca cgacgaggtt tgaaacaacg atcagtgcca aaagcatttg attcatataa
    26521 ttgatcaaag caagaacttg tccttgttgc aagctaccaa tatttacttt gatcccgcca
    26581 actgtcagca aacagatgat cccgacattc atgatcaagg ttgtagcagg tgataatagg
    26641 gcagagatat tggaaacacg taaataattg ttcgctagat catttgtgct tttatcgaac
    26701 ttctctgttt ctttttttgt ctgcgcaaat gcgcggatga cacgaacacc gctaagattc
    26761 tgactaacgt gttcattgag ctgatctagt ttttcttgca ctttttggta gagaggaacg
    26821 gtttttttga tgataaaaaa taaaatgatt gagaaaatag gcaataatgc taagaaaaac
    26881 agacctactt cccagtcgat cacaaaagcc atgaccactg acccgatact taaaaacggt
    26941 gctctgatca ataaacgaat gaccattgct aaagctagct gaagctgatt gatgtcgttt
    27001 gtcattcggg tgatcaaggt atctgttcca aaatgattca actcgttgtg agagaaagta
    27061 ttgatttttt tgattagctg attacgtaac tctgtaccaa atccttgtga agctactgaa
    27121 gcatagtatt ggcaaatgat agcacaaatc agaccaatca cagacatagc gaccatccat
    27181 aagcccattt caatgatttt tcctcggtca ttcattttta gtccattatc gatcaaggaa
    27241 gccatcatta aaggcaggac aagttcgaag acagcttcaa gaaatttgaa gaacgggccc
    27301 aaaatgattt gcttacgata gtcttttgca taacgtaata actgaatcat atgattcctc
    27361 ctattattta tttgtccaca attgaaaaaa caagtactac cacattgtag cttaggaaat
    27421 ttagaatgaa aagagaacaa gccttttcat aaatgaaagt tttattatga agaagcttta
    27481 gaaattgaat agactatttt ttttaaaaaa aagaaaatga gaaaacatgc cagtctcttc
    27541 attcatagga acgtctattt tacttaattt ttctataaat gaattctgca taaaaaatat
    27601 atcaagtaaa tgtttataga tgaaactcta tttacttctt ttttaatttg ttcttgcaat
    27661 cttttttgct acgtaatttt tgtaaaaaag tgggttgaga gaaatctaat tgattttcaa
    27721 agaaggagta tgaaaatgag aaaaatattt attcgtttat tgtgggtact atcttagagg
    27781 aataaataat agtggagaaa actatggttt ggcgcagatt ctatcaggtt tgatggaacg
    27841 aagacaacct cccgacatca agtcaaaagc tacttgagat tttgatctga aaataaaaaa
    27901 agaaaacaag gtaggaacat caatgtttct accttgtttt cgtaatcaat gggaaaaaac
    27961 taagagtggt gtacgtaatc aataaaaagg atggtgacaa cagtacctct ttactctctg
    28021 aaagcatcat aactcgtttt tcctcattat gccaataaat tgttgttata ccacatataa
    28081 ggatttgtaa tagctaaaaa cagacaggaa agttgaaatc tgtgaatctt attttgtatg
    28141 gaaggattta tagaacgcaa aaatcaagat aaagatgaat aaaaatcctg tttcggctat
    28201 atattgcgta tctacgccaa taaaacgagt ttgttctgtc atagccatat aaagcaaagg
    28261 caaaaataca actacagcga gataagatcc gatgatttct cgaaaagttt tccaggaagt
    28321 atgtttcctg tttttatatt tatccgattt cattgaatag tcatagcctc cttattcttt
    28381 catatgttga aattccagta taaaaactgg aaggaactgt acgtttttta gaataaaaat
    28441 tataagggat aagtaggctg ctgtctataa taagatatat ttttcaattc tttattaaag
    28501 attttattga caaaatgaat ccgttttcta tgatggagga ggggtgaata agttgttgaa
    28561 gaaggaaatt ttatgttact tagagaacca gacagccttt ttcgatttag aacatatgaa
    28621 cgaggtcttt acagcacaaa ggttagctga tcattttggg gtaaaaagaa acacagtcag
    28681 tcattatttg aaccagttaa atgatgagca actactagtc aaaatcaatt ctcgaccagt
    28741 gatttatttc cacaaagaag cttttgaaaa acaatttttt aagttacgca cgaattttta
    28801 tttttctatc gatgatctca aagaggaaca gccttttttc gcgcaaccaa aagacttatt
    28861 ctcttttatg atcggatacg acgccagttt gaaagaaagt atcgaacaaa tcaaaacagc
    28921 tctttactat ccagatggcg gattaccact tttgattaca ggcgaaagtg gcacaggtaa
    28981 aagttattta gttaatttgg tctatcagta ttgtctgctt catgatctgc tagaagattc
    29041 tgcaccattc atcactttta attgtgcaca atatgcagat aatcctgaac ttttgactag
    29101 caatttgttt ggacatgtta agggagcgta cactggtgca gaagaaaata aaaaaggggc
    29161 ttttgaagca gcagatggtg ggatcttgtt tttagacgag gtacatcgct taacaccaga
    29221 aggtcaggaa aaactgttca cctatcttga tcaaggtgtg atttatcgta tgggagaacc
    29281 taatttgtca cgccggatca aaacacgtct cttttttgct acgactgaag agattactag
    29341 tcatttctta acaactttca ttcgaagaat acctatccga atcgaactac ctgcacttaa
    29401 tcagcgtagt cgtaatgaac ggctagaact gatttactct ttttttctcg aagaacaaag
    29461 aaaaatgggg agccctttgt cagtcagtgg accagctttg tcacttttaa caagtcagaa
    29521 attatccgga aacataggag agctgaaaaa tatcgtcaaa gtttcagcag caaaagcata
    29581 tgctgaacag cgtgaacagc ctgaaatcca tgtcacgatc catcatttgc aaaaagaact
    29641 acttgcgcag cctattacta aaaatacagc acagcaagga atctatatta cgcaagacca
    29701 gaccttagag caattaatgg agaagcaaca gcccgaacag cagcgaatcg ttaaaagttt
    29761 tgagcaaatc ctaattgatt tcaagaaaaa taactgtctg ctatattctt gcgaaggaaa
    29821 attaaagcaa gaagtgattc aattatttga ttttttgctg tttgagacca gtagacaaga
    29881 aaaacacgag ctgctggttt attggacaca atctatccga gagacctttc gacaaatgga
    29941 aactgcctat caaatcaaat tcgatggaaa cagtgtctat gccttgagtt actatctcta
    30001 tcagcgaagc actatcaaat ggttaccgga agaacatgat attatccaac taatcaaaga
    30061 attagaacaa caagtttctc agtcttatcc atctagttat cactatgtcc aacgaattct
    30121 ggaattaagt aagatcaaat tagatattga agacacaagt atggatcgga ttttactgac
    30181 gatctatcta aaaaaagcga aatggtcaaa agaaaaacga ctgccaaaag cgatgattgc
    30241 tgctcacggt tatgcaactg ctagcagtat ggcaaatgta gtaaatcgtt tattacaaga
    30301 ggatctattt gaatcatttg atatgccact agatgtcaca ccacagcaga ttgcttcaga
    30361 aatccttgat tattgcgaaa acagcgatgt ttcaaatgga ttgatcatat tagtagacat
    30421 gggatctctg aaagaaatcc atcagttttt taaaaaacag ttatccgtac cgcttttgat
    30481 tttgaataat gtgacgacac ctttagcaat cacagtaggg gaatgcctgc aaaaaaatgt
    30541 atcattagaa gagatagcag aagagactgt tcgacagatc cagccagaat ggcgactgct
    30601 ctatccagag gaaaacaaac ccaaagcact cattactact tgcttcactg gaatcggtac
    30661 ggcggtccac ttaagtgaac tgctagaaaa aagcttacct acggcttgtc agttgaaaat
    30721 catcccatat gaatatcagc aattaaaaga taagaaaaac agtgacccat tattttccat
    30781 atacgaagtc gtaggaatga ttggcaccac agatcctgat atcaccaata tcgactatct
    30841 ttcattagaa gacctcatct cgggggaaaa gatgtctgta ctagctgaat ggttggacac
    30901 tactatgaat gcttcagaga aggaaatatt caatcagcgc atcattcgta atttttcatt
    30961 ggaaaaagta ctggattccg tgactattct agatacagag aaggtgatgg gagaaatcga
    31021 tcattttatg agagaattag aggtgcagtt gaatcgaagc atcagcaatc ccaaaaaatt
    31081 agcgttgtat gtccatgtga gctgtctcat tgaacgattg atccgacaaa tgccaatcga
    31141 aacctatcaa ggattagaga aatggaagca gtgtcaaaaa gaagggttat ctgctattaa
    31201 atctgcgttt agtgtcattg aagagcatta tagtgtcatg atccccaatt ctgagattgc
    31261 ctatatctat gatattttga gtgaagatac agagtttctc tcgatagaag aagaattttg
    31321 aacataagca agttgttgcc actaattttg gcatgcaact tgctttttta gtatgtgtaa
    31381 gtgaaaagag gagatgaaaa agtggataga gaaattatct tagcttccca tggaaaattt
    31441 gcttcaggga tattagattc attagagctg atctatggga aaaatcattc tattactgta
    31501 ttcgattgct atactgatga gaattttgat ttagcggaaa cagtaaggca gctttttatg
    31561 aggtacaaag ataaagaaat cattgttctg acggatcttt ttggcggaag tgtcaacaac
    31621 gaattcttac aatatatcaa tcgggatcat gtctatctcg ttgccggatt gaatttgcca
    31681 ctattgattg agctagtatc tcggttggac gctgaagtag agacaactgt tttgatccag
    31741 caggtgctaa ctgattcaaa aaaaatgatc cagttttgta acgagcggct caatcagaaa
    31801 atagaagaag acgaatttta ggaggaagaa aaatgattgt attgacaaga gtcgaccatc
    31861 ggttattaca cggacaagta gctttttcat ggacacaaac aataggcgca gactgtattt
    31921 tgattgctaa tgatgatgta cctacgaatg agatacgaaa gacaacgatc aaattagcca
    31981 agccacaagg agtcaaacta gtgatcaaat caattgatga ctcgattgcc gcgttgaaaa
    32041 gcggggtgac agataaatat aagttattca tcgtagtgga atcgatcgag gatgcatata
    32101 agctggcaga agcgtatcca gaaatcaaaa ccatcaactt aggagggatc aaggcaaaac
    32161 ctggtactcg cagcatcgga aaagcggtaa atattttacc agaagaggag gaacgcttga
    32221 aacgattaat tgacaaacaa atagaagtag aaatccgtca agtaccagca gataaaaaag
    32281 tggatgtaag agaagttttg taagaaagga agaacctcaa tgattgtaca agcagtctta
    32341 ttaggaattg ttgcatttgt cgcacaatca gaatatgcac tagggacatc gttgctttct
    32401 cgtccgattg tgacggggct gtttacagga atcgtgttag gtgatgtaaa aactgggatc
    32461 attatgggcg caactttaga gttagcattt atcggatcgt tctcagtagg tgcttcgatt
    32521 ccacctgatg ttgtgaccgg tgggatttta gggacggctt ttgctattac agctggagcc
    32581 ggtacagaaa ccgcgctttt actaggtttg ccgattgcta cgttgacatt gatattgaaa
    32641 aatatttact tagggctttt gattccaatt atgaaccata aagcagacaa ttatgcagaa
    32701 gaaggaaatt ataaaggagt cgagcatatg cacttgcttg ccggtatcgg tctttccttg
    32761 atgcttggtg ttgtggtaat ggtttcttat atggtgggaa gcaatacgat cggaaatcta
    32821 ttaaatatga ttcctgactt cgttcaaaag gggttgtcag tagctacagg gttgattcca
    32881 gctcttggtt ttgcgatgct tgctcgtttg ctgatcaaca aacaagttgc accatatttt
    32941 ttcttaggtt ttgctatagc ttcttactta gagattcctg tgaccggagt agctattttt
    33001 ggtgcgattt tagcagttgt ggtagtcaat attatgaatg tccgtcaact accacttcaa
    33061 acaactgcag gggaggtaga agaagatgaa gaattctgag atcaaaaaca gcaaaataac
    33121 gaaaaaagag ctaaatcacg tattttggcg ttcttttcaa atggagtttt cttggaatta
    33181 tgaacgtcag atgaatatgg cttatgttta tgcaatgatt ccgattttga aaaagttata
    33241 tcagtcgaaa gaagaaatgg cagcagcttt gaaacggcat ctagagtttt ttaacacgac
    33301 cccacatatc gttacactga ttttaggaat cacggctgca atggaggaag aaaataagga
    33361 tgatcctgaa tttgatgtga ctgcgatcga tagtatcaaa acatctttga tgggacctct
    33421 tgcagggtta ggagattctt tcttttgggg aactttgcga ttgattgcca caggtgtggg
    33481 tacctcttta gccatgcaag gaaatatttt aggccctatc ttgttcattt tgattttcaa
    33541 tattccgcac attctgtttc gctatctagc aacaggttgg ggatatcgct taggaacggg
    33601 ttttttgaaa aagatccagg caaacggtat gatggaaagt ttgacattag gcgcgtctat
    33661 tattggactg atggtcgttg gagcaatgac tgccacgatg atcaccatca atattccttt
    33721 aaaaatcggt tcaggagaaa atgctgtgac tgttcaaagt atttttgatg atatcgttcc
    33781 aaatatctta tgtcttggag catttggcat agtgttttat ctattgaaga aagaagtgaa
    33841 accattaacg atcttgatcg gactagcttt ctttggaatt tttggttcgt ggatagggat
    33901 tttttaaaaa aggagcagag aaaatgttta cgatgcaaga ttatatctat gaagaaaagg
    33961 aagtactaag tacgatcttg aaaaagaatg atttttcgac aagagaacat atgaaaaaaa
    34021 cagtgaattt actgatctta gcaacgggtt catcttataa cgcttgttta gcagcgaagc
    34081 cagcattgga atcttatggt gatcttactg tcgatattca agaacctttt tattttttca
    34141 attatggaaa actttctcct tcaatcgata ctgtgattgc tgtgtcacaa agcgggaaaa
    34201 gtgcttctac tgttgaagca gtaaaaatga tacaaaaaca agggttacct gttgttgcta
    34261 tcacaaatga cgtgcaaagt ccacttgctt tagaagctgc acaaattatt gatttaggtg
    34321 ccggggtaga atcagtaggc ttcgttacaa aaggctattc tgcgactgtt ttacagttac
    34381 tactcttagg gataggaatt ggaataagta aaaataaaat cagcaaaaaa atagaacaag
    34441 actacatgca acagttgcgc aaaataatca accatttacc agcgattatt caaaaaacgg
    34501 aagaattttt tgatggatat caaagtttat ttcgtttagc acagcgtttc gtcaccattg
    34561 gatatggtcc aaactgggga acagctaaag aagcagagac gaaattgact gaaacaatcc
    34621 gcgttccgtc acaaggattt gagttagaag cttatatgca cggcccatac ctggaggcag
    34681 atgcttcgca tttgctattc tttattgaag gggaaagtgt aaataaggaa cgttcgcaaa
    34741 agttgcaaag atatatgagt cggtacgttg gagagactct caccattacc acaaaaaaag
    34801 caagaaacga gaaaacactt ggattagcaa tagaatgtga tgaatatctg tctgtattag
    34861 cgcttgtcgt tccgtttcaa ctattcgctt ataaaaccgc agtagctaaa ggtattgact
    34921 tgaacaaaaa gatttttgaa gactttgata cagtcttgaa aagtaaatta taagaggtgg
    34981 aaatcatgct gaaattcaat gaagaagaac aaatcaaagc aataaaaggc gcactagctt
    35041 tacgtccgca agtagaagaa atcatcgata aactttatgc ggaaaaattt gacgctgtct
    35101 attatctagg aatcggtgga acgtatgctt cctcgatgca agctgtcact tatatgaatg
    35161 ggaaaagcaa cttgcctgtc tttgtacagc atgctgcaga atattacact actggaaaca
    35221 aaagattaac aaaagattct atcgttattt tgtcctctgt taccggtaca actcaagaag
    35281 tagtgaaagc agtagaacaa atcaagaaag taggagcgac actgattgga tttatcgata
    35341 aagcgaacag taagttgtct cagctatgcg attttgtggt cacttatcca gctcctggaa
    35401 cagaacaaat caaatttttt atggcagcag atcgattgat gtatttgaat ggagaattcg
    35461 aagcttattc agaatactat gaacagctcg aacgttattt accaacaggg ttagtggaag
    35521 cagagaaaaa agcagatgca tttggcttat catttgcaga aaaacatcga cgtgatagta
    35581 tgcattattt tattggagca gggaatcaat ggggagctgt ttattcatat gccatgtgtt
    35641 actgggaaga acaaagctgg cttccatcga aatctatcca tgctgccgag tttcttcacg
    35701 ggacgttaga gatcgtagaa gaaacaaccc cagtcacatt atttttaggc gaagatgaac
    35761 agagagtgtt atctgaacgt gtggctaaac ttttgccaaa aatttgcagc aattatacat
    35821 tgatagacac aaaagactat ccagtagaag gtatcagtga aaaatatcgc ggacgtgttt
    35881 tgtctttctt attgatgcat gtagtgacac aacgcatcga tgctcatgtg gagcagttga
    35941 actgccatcc attagagata cgccgctact atcgtcagtt tgattattag gatagactgg
    36001 ataaaaagaa tataaaaaat aaagagagca gcgataactg ctccctttat ttttttaaaa
    36061 tattggcatc aattacgtta taaaacacat tttttgcatt atctacagtt caacttataa
    36121 tctgtttaat gggacatgtg ggtgccaacc attttttgtt atgcaatagt actatttagt
    36181 tgttgcatgg atccgtagta aaagtccaag tacaacgagt tgcgccagtt tacatagcgt
    36241 tttgtatcca gaatgttgac taaaacaaaa gttcctatgt caaccgtcaa cagagacaat
    36301 ctgtccgttg caggacctga cagatttaga aatgttcaat ctgtctctta tgtattttaa
    36361 atcaatactc actaggagaa gtttcctaac ctcctaatag taatgctggt agtaacattg
    36421 tcaaaactgc ttcctcttag gaacaagcaa agcataacga gtgtaaaaat aaaatgtaga
    36481 ctattgtaac atatcattga ttatttcaag taaaaacgat aaaagaagta aacaaacact
    36541 taaaaacaat ggaaattagt cccaacttta agaaatgtat actataatgg aaattatcaa
    36601 ttatttattt ggaggaatat ccatgaaaca aaaaatcgca gttcttggtc ctggatcttg
    36661 gggcactgct ttagcacaaa cattggcaga aaacgggcat gatgtccgta tttggggaaa
    36721 tgtacctgaa cagattgatg aaatcaataa gtatcataca aatcagcatt ttttacctga
    36781 tttgacgatc ccagaatcga ttatcggata taaagaattg gcagaagcag tggataacgc
    36841 agatgctatt ttatttgttg ttccaacaaa agcgattcgt tcagtcgcac aggaacttat
    36901 tggtaaaatg aatactaagc caatcattat acatgcaagt aaaggactag aacaagatac
    36961 gcataaacga atctcagaag ttttggctga agaaattcca gaagaaaaaa gacaggcaat
    37021 tgttgtatta tctggtccta gccatgctga ggaagtggca gtacatgata tcacaacaat
    37081 tacagctgca agtattgatc aaaaagcagc agcctatgta caaaaactgt tcatgaatga
    37141 ttatttcagg atttatacaa ataatgatgt gattggcgta gaaactggtg cagcactgaa
    37201 aaatatcatt gcaattggtg ccggcgctat ccatggatta ggattcggag atgatgcaaa
    37261 agcagcaatc atgactcgag gattggcaga aatcagccgt cttggtgtcg cgatgggtgc
    37321 caatcctctg acatttatcg gtttgagtgg tgtgggggac ttgatcgtta cttgtacaag
    37381 tgttcattct cgcaattggc gtgccggtaa cttgttagga cagggacata agctggaaga
    37441 agttctagaa aacatgggaa tggtcgttga gggtgtggca acgacaaaag cagcagtaga
    37501 gctagctcaa cagctaggtg ttgagatgcc aattactcaa acaatctata atgttttgta
    37561 taatggagaa gatatcaaaa aagcagcaaa agaaatcatg ttacgtgacg gaaaaatgga
    37621 gaatgaattt tctcttcgtt aaatagatga tcaatagtta atcgt
//
LOCUS       DAYNVV010000023        37473 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.023, whole genome shotgun sequence.
ACCESSION   DAYNVV010000023 DAYNVV010000000
VERSION     DAYNVV010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37473
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.023"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..520)
                     /locus_tag="ACGXWR_001308"
     CDS             complement(<1..520)
                     /locus_tag="ACGXWR_001308"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802891.1"
                     /translation="MVQGLFGGGTSYEGQSISDIKEDVNNWKIYTENVKSQIVEKKEA
                     LIKNGFWNKIPWNFQQTINESIFCLGTFLSDFQIVESAFEENFISEREIKLLRKIGKN
                     SVQFNHSYGKYFKEEYEWREYGNPEFEIVESIYQHGRDFFVTLQDASNAAGRLEDYMS
                     NNSIYNKVNIFGN"
     gene            complement(620..1945)
                     /locus_tag="ACGXWR_001309"
     CDS             complement(620..1945)
                     /locus_tag="ACGXWR_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802892.1"
                     /translation="MENIEETFLKVLSPYISDSILRFQEQEKNYKFGFDIKNYNDSLH
                     VVFQYNKTGKIGIKEVHIFQIFLAKVNIEASKSKLNYTTLLDTNALFFSKKLLPYLHS
                     YEWALRKLIYLLAPAYFSDNWAEESIPNEIISSIKRKQIQAIGKFDSKNLLQWIDLYD
                     FEEYLFGENYILVTQENEENIVRYKEISQDQLLKLFQDNSHTISDSYSLWSEVFSKYM
                     DVKLEEIQTDMSLIREGRNIVSHNKEIEMALYQKLIKKLKRYTNQLEKAFQKILAGDI
                     AGEDLSDMSDDFEGYIGNYFSNIDLAGVTKLSESLSAMKVLNTDSMKKSMESIGQTLS
                     VQQEIMQNFDTEGIRRATEGINQSLQSIKILNTDSMKRSIESIGQTLSALSAQRAIMQ
                     NFDTKGIRSATEGINQSLQSMKIVNTDSMKRSMESIGKISSTNQVLKSE"
     gene            complement(2114..3043)
                     /locus_tag="ACGXWR_001310"
     CDS             complement(2114..3043)
                     /locus_tag="ACGXWR_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802893.1"
                     /translation="MRSDSRFFVSNLQDDELIRQIDSLLETITESDKRIFLNYVELTR
                     HIIELDKLFNVFRYNLTNLLKHFTIFTNDLIESTGEKLTEDQYYYQINALTINLISSA
                     KTLTESIEVCMKNFLAEKDFKSFKNKILSKPYDEHFSYRFLLHMRNYSQHGHLPVNIH
                     QQRVYFDLDEILAMPHFDFNGQLKKELDVLRKDIYNQFRDSPRISYVYTVAKFNLVIT
                     EIYFNYLKEIKPILIKLNDEKNELLLNTKFQLINSDGSSSDMLFYEFDGENYHCFNRK
                     DNSISMYADIKREVKKILKVEEQYYKEIEKRNQ"
     gene            complement(3291..3605)
                     /locus_tag="ACGXWR_001311"
     CDS             complement(3291..3605)
                     /locus_tag="ACGXWR_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802894.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDRIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSETFEIDPDYYQPQEVFREFRNQIIRSSNI
                     EN"
     gene            complement(3682..4176)
                     /locus_tag="ACGXWR_001312"
     CDS             complement(3682..4176)
                     /locus_tag="ACGXWR_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802895.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTIDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLKNDTEKPIRPQQW
                     SIENKDGEELYEYAMILDNPEYIESDKEETVNYYYELPIERQDYQIVVRRANGYFVGL
                     PFTL"
     gene            complement(4169..4483)
                     /locus_tag="ACGXWR_001313"
     CDS             complement(4169..4483)
                     /locus_tag="ACGXWR_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802896.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGVFGSKANMFRVMVSNLP
                     VLASPSNNKFNDSESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            complement(4699..6090)
                     /locus_tag="ACGXWR_001314"
     CDS             complement(4699..6090)
                     /locus_tag="ACGXWR_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFK0802897.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            complement(6075..6686)
                     /locus_tag="ACGXWR_001315"
     CDS             complement(6075..6686)
                     /locus_tag="ACGXWR_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HFK0802898.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            complement(6690..6887)
                     /locus_tag="ACGXWR_001316"
     CDS             complement(6690..6887)
                     /locus_tag="ACGXWR_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802899.1"
                     /translation="MQLILQISTHDFLELDELCESVKKATNEKITVTNYIELMIQEEL
                     KMKNEIESDFKCCSLEKNVRG"
     gene            complement(6901..9594)
                     /locus_tag="ACGXWR_001317"
     CDS             complement(6901..9594)
                     /locus_tag="ACGXWR_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFK0802900.1"
                     /translation="MKIVKEKIASRKIHWLALSILVLMFIVVFTGNVVQASIFNWFDD
                     TESQTEFLNNPVYQSYLKKYNGNFYSQFGLWIGWSVIKSMFAIVDGIQNMIPEVLDLF
                     SFIESTGMNKVYQSVLSTVVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSVALI
                     LLMPTLIGSTEKLSGIMFAKTLYNDATSINNQDGGVAWSLIEQGVTDLAYINKTDQYS
                     TIDKTNDRNNLTKENFWKTDLTQVLTDNVIDKMEKENPTADNLRYELVENSDNEFVAT
                     KFSDNFLSTFVDGIKSGYYRYQANLWGISFGLIALAVAYVFSAFIIITAILELAFKRV
                     LGVLVFATDLETGQRSKQVLSDILQCYLTVGFQGFGLSMFAMFINYLNTGEGISANIF
                     IKTIAYICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGTGGMNRS
                     KGGKNNGGNDQAEGEERKPERNFGQSLSKKANKTGKALGYAHERGLSGLASDGSTMAS
                     ERATKPFKSMRDIANDTKSKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPT
                     RLSDRKDGAKVENADSIMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMH
                     GQAKSAEELINQKRHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAK
                     NSNTGLEKLVKENPQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQG
                     TKTIDVRENLQSSSTSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDV
                     RENVQSSTSSQGFKTVDVRENVQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIID
                     SEIRENDKGSKPRRRFTYEDNELFRDTLNDPNPLFDSLLKK"
     gene            complement(9581..9799)
                     /locus_tag="ACGXWR_001318"
     CDS             complement(9581..9799)
                     /locus_tag="ACGXWR_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802901.1"
                     /translation="MIENRLIDQVWCLDQNTDNLELIETICFNTIVLDLRSENDNCVT
                     HIIIDRKTAQKLSESLRKWAEGGNNENS"
     gene            complement(9875..10888)
                     /locus_tag="ACGXWR_001319"
     CDS             complement(9875..10888)
                     /locus_tag="ACGXWR_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFK0802902.1"
                     /translation="MEEIDKLIAQYAYSKDDVYAEKYLKYPIFLDKHKKYKKMKQSTK
                     KVYMYLKKQNEYSLENSKVDSKGRIFLIFAIEKIAEKSCLTKKTVISALRELEEYKLI
                     TIKKNGFNKKTGKNNPNFYYLLKPEFSEGDFYKKKCIEENLHLPTNQHYSPSEKNTPS
                     DKSTFDGDKSFPLPGEKFLQELNHSSKDFKDFKESQNADFIDSLSVENKKLDEILIES
                     LIEKEWLYQVWGDNIVNCLKLVGNNDYSQFYDWYKKFKYAIKSAEKEQKIQLKIIYEI
                     CNNKYFVDYVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNKALELIELQISEGI
                     DKQ"
     gene            complement(11092..11373)
                     /locus_tag="ACGXWR_001320"
     CDS             complement(11092..11373)
                     /locus_tag="ACGXWR_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0802903.1"
                     /translation="MKSEIQVILPSDLDQELRRYFYRVAKEAVDQVRIETSLSKEVFR
                     LGEACKYLSCSRSTLKKFIREKGLKVSIIGDCQFIRKEELARFIKEYEV"
     gene            complement(11424..11630)
                     /locus_tag="ACGXWR_001321"
     CDS             complement(11424..11630)
                     /locus_tag="ACGXWR_001321"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFK0802904.1"
                     /translation="MKPKDFRKFCGLSQSELAEKYGISVQAVRNKESGKTNYSPEEMI
                     ILKYLVKEKGIENITIDQIFFNEK"
     gene            11794..12525
                     /locus_tag="ACGXWR_001322"
     CDS             11794..12525
                     /locus_tag="ACGXWR_001322"
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFK0802905.1"
                     /translation="MFDKNINSEIGKRIQEIRVSLGYTLEEFGENLTPPASKSNVSRW
                     EKGKNIPNKARLLSIAKLGGVSTEYLLTGNSQKTKKYIKYLFNEIFFDNGTFHNKFKD
                     FGKDRDRLGLYDLFLAVSKTYSLDKSPSLKDNFVEMIIDDVYKKLLQTDKSDDQLILG
                     FIYICLDEKLSNRQKSLKSINYEVFNYLGVAFGLIDSEIKSTNAGNDEDLLNYLKELT
                     SFIDEIKTTTFNKKKYFQNQYDIEE"
     gene            12579..13724
                     /locus_tag="ACGXWR_001323"
     CDS             12579..13724
                     /locus_tag="ACGXWR_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFK0802906.1"
                     /translation="MATIKQYEKKDGTKAWMFQTYLGISPLTGKEVRTTRRNFKTKKE
                     AQIELNRLLVDFEENGLKRETNETFQEVYDLWYESYKTTVKEVTQLKIEIKFNKWILP
                     KYGQFRIKEITTKHVQKILNQWAKTTDQYKVLHSTVSRIFKYAMTLGLITKNPCELVI
                     MPNRNVEKKKDTVKIYSRDQLETLFQYLESKRSTYRAEYDKTLLRFLFFSGCRISEAL
                     ALDWSDIDFDSNTVTINKTLSQTKYGYKISSPKTRNSYGSLSLDNKTINWLKKWQINQ
                     KRYMLTLGITDPTMIFCGIYKEIITKHAIYSRMITICKNSGIPFLGNHVTRHTHASML
                     LESGVSMKEVQERLRHSSIKLTMDTYAHLTKETKEKTVEKLAEHLNF"
     gene            complement(13809..14114)
                     /locus_tag="ACGXWR_001324"
     CDS             complement(13809..14114)
                     /locus_tag="ACGXWR_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HFK0802907.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(14139..14570)
                     /gene="ruvX"
                     /locus_tag="ACGXWR_001325"
     CDS             complement(14139..14570)
                     /gene="ruvX"
                     /locus_tag="ACGXWR_001325"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HFK0802908.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(14567..14833)
                     /locus_tag="ACGXWR_001326"
     CDS             complement(14567..14833)
                     /locus_tag="ACGXWR_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HFK0802909.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(15088..15813)
                     /locus_tag="ACGXWR_001327"
     CDS             complement(15088..15813)
                     /locus_tag="ACGXWR_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFK0802910.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(16174..16244)
                     /locus_tag="ACGXWR_001328"
     tRNA            complement(16174..16244)
                     /locus_tag="ACGXWR_001328"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16210..16212),aa:Gly,seq:ccc)
     gene            16361..17113
                     /locus_tag="ACGXWR_001329"
     CDS             16361..17113
                     /locus_tag="ACGXWR_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFK0802911.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            17129..17608
                     /locus_tag="ACGXWR_001330"
     CDS             17129..17608
                     /locus_tag="ACGXWR_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFK0802912.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(17859..19439)
                     /locus_tag="ACGXWR_001331"
     CDS             complement(17859..19439)
                     /locus_tag="ACGXWR_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HFK0802913.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(19432..20175)
                     /locus_tag="ACGXWR_001332"
     CDS             complement(19432..20175)
                     /locus_tag="ACGXWR_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0802914.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(20351..21126)
                     /locus_tag="ACGXWR_001333"
                     /pseudo
     CDS             complement(20351..21126)
                     /locus_tag="ACGXWR_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
     gene            complement(21374..22210)
                     /locus_tag="ACGXWR_001334"
     CDS             complement(21374..22210)
                     /locus_tag="ACGXWR_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HFK0802915.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(22221..23150)
                     /locus_tag="ACGXWR_001335"
     CDS             complement(22221..23150)
                     /locus_tag="ACGXWR_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HFK0802916.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            23342..23695
                     /locus_tag="ACGXWR_001336"
     CDS             23342..23695
                     /locus_tag="ACGXWR_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFK0802917.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(23769..24425)
                     /locus_tag="ACGXWR_001337"
     CDS             complement(23769..24425)
                     /locus_tag="ACGXWR_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFK0802918.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            24651..26585
                     /locus_tag="ACGXWR_001338"
     CDS             24651..26585
                     /locus_tag="ACGXWR_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFK0802919.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(26671..27894)
                     /locus_tag="ACGXWR_001339"
     CDS             complement(26671..27894)
                     /locus_tag="ACGXWR_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFK0802920.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(27888..29759)
                     /locus_tag="ACGXWR_001340"
     CDS             complement(27888..29759)
                     /locus_tag="ACGXWR_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HFK0802921.1"
                     /translation="MKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQIDYIHQGVG
                     YGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYWGEIHERDQR
                     MVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQFFKIIVGTII
                     QKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYGLIYSVLEPE
                     KPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAMLWADLLPFKL
                     GEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLWLNKIFLLLA
                     LPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPNFHTLTNEKY
                     LKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKTYGQFIVRNN
                     VRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLYETGFAIECS
                     PEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLMTWENTFIPG
                     LEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKNNKKRLKLC"
     gene            complement(29780..30898)
                     /locus_tag="ACGXWR_001341"
     CDS             complement(29780..30898)
                     /locus_tag="ACGXWR_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFK0802922.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(30981..31814)
                     /locus_tag="ACGXWR_001342"
     CDS             complement(30981..31814)
                     /locus_tag="ACGXWR_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0802923.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(31807..32724)
                     /locus_tag="ACGXWR_001343"
     CDS             complement(31807..32724)
                     /locus_tag="ACGXWR_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0802924.1"
                     /translation="MIQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(32747..32926)
                     /locus_tag="ACGXWR_001344"
     CDS             complement(32747..32926)
                     /locus_tag="ACGXWR_001344"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802925.1"
                     /translation="MNKINENTSNTVLPATYSDATSYLTTAAYNYWQTGDFENSYLKE
                     AENFAHKYGVKLTGD"
     gene            complement(32951..34075)
                     /locus_tag="ACGXWR_001345"
     CDS             complement(32951..34075)
                     /locus_tag="ACGXWR_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFK0802926.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            34258..35166
                     /locus_tag="ACGXWR_001346"
     CDS             34258..35166
                     /locus_tag="ACGXWR_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFK0802927.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            35307..36920
                     /locus_tag="ACGXWR_001347"
     CDS             35307..36920
                     /locus_tag="ACGXWR_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFK0802928.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT        11663 a         7171 c         5763 g        12876 t
ORIGIN      
        1 tatttccaaa tatatttact ttattatata ttgaattgtt gctcatatag tcctccagtc
       61 gtcctgctgc attacttgca tcttgtaacg tcacaaaaaa atctctccca tgttggtaaa
      121 ttgattcaac gatttcaaat tctggatttc catattcgcg ccattcgtat tcttccttaa
      181 agtattttcc gtaactatgg ttaaattgca cagaattttt accaattttc cttagaagtt
      241 ttatctctct ctcagaaata aaattttcct caaaagctga ttcaactatc tgaaaatcac
      301 taagaaatgt tcctaaacag aagattgatt cattaatagt ttgttgaaaa ttccatggta
      361 ttttgttcca aaaaccattc ttaattaaag cctctttttt ttcaacaatc tgtgatttta
      421 cattttctgt atatatcttc caattattga cgtcttcctt aatgtccgaa atcgattgac
      481 cttcataaga agtccctcca ccaaaaagtc cttgaaccat tttatctcat cctctctata
      541 ataattactc taaatccaat acttgctaca aatgatagca tttcgtgtgg taacatgatt
      601 gccatcgttc ctgttttatt tactctgact tcaatacttg gtttgttgat gaaattttac
      661 caattgattc catcgatcgt ttcatggaat ctgtatttac tattttcatt gattgtagag
      721 attgatttat tccctctgtt gcacttctga tacctttagt atcaaagttt tgcatgattg
      781 ctcgctgagc tgataaagct gataatgttt gacctattga ctctatcgac ctcttcatgg
      841 aatctgtatt taatattttt attgattgta gagattgatt tattccctct gttgcccttc
      901 tgataccttc agtatcaaag ttctgcataa tttcttgctg gactgataat gtttgaccta
      961 ttgactccat cgactttttc atggaatctg tatttaatac tttcattgct gatagagact
     1021 ctgacaattt agtaacacct gctaaatcga tattactaaa ataatttcca atatatcctt
     1081 caaaatcatc tgacatatca ctaaggtcct caccagcaat atctccagcc aatatttttt
     1141 gaaaagcttt ctctagttga tttgtatatc tcttcaattt ctttattaat ttttggtata
     1201 aagccatttc tatttctttg ttatggctta caatattcct accttctctg attaaactca
     1261 tgtctgtttg aatttcttct agcttaacat ccatatattt actaaatact tcactccaca
     1321 aagaatatga atcagatata gtgtgactgt tatcttgaaa taacttcaat aattgatcct
     1381 gagatatttc tttatacctt acaatattct cttcattttc ttgtgtaact aaaatataat
     1441 tttctccaaa gagatattct tcaaaatcat ataaatctat ccattgtaaa agattctttg
     1501 agtcaaactt tcctattgct tgtatttgtt ttctttttat tgacgaaatg atttcatttg
     1561 gaattgattc ctctgcccag ttatcagaaa aatatgccgg agctaataaa tagattaatt
     1621 ttcttaatgc ccattcgtaa ctatgcaaat acggtaatag ttttttcgaa aaaaacaacg
     1681 catttgtatc taaaagggta gtgtagttta attttgattt acttgcttca atattgacct
     1741 tagctaggaa aatttgaaat atatgtacct cttttattcc tatcttacca gtcttattat
     1801 attgaaatac tacgtgtaac gaatcattat agttctttat gtcaaagcca aatttataat
     1861 ttttttcctg ctcctgaaat cttaagatag aatcactaat atatggtgac aacactttca
     1921 gaaaggtttc ttcgatattt tccattcttc cttttttagg ataatataaa tattcaacaa
     1981 cttgcttact aatatgtcat caacttcttt cctttcaaca attttaattt tcctattaac
     2041 ttgatatttg ctacataagc cacaactagc aaacagaaag agaacttttt ctttaccttg
     2101 ataactgtgt taattactgg tttctttttt ctatttcttt atagtattgt tcttctactt
     2161 ttaatatttt tttaacttct ctttttatgt cagcatacat agatatactg ttgtcctttc
     2221 ggttgaagca gtgataattc tcaccatcaa actcataaaa aagcatatca cttgagcttc
     2281 catctgaatt aattaactga aatttggtat tgagtagtaa ttcatttttc tcgtcattca
     2341 actttattaa aataggtttg atctctttta aataattgaa atatatttcg gttattacta
     2401 aattaaattt cgctactgta taaacataag agatacgtgg ggaatctcta aattggttat
     2461 atatatcttt ccttaaaaca tctaactcct tttttaattg tccgttaaaa tcaaaatgag
     2521 gcattgctag aatttcatcc aaatcaaagt acactctttg ttgatgaata tttactggca
     2581 gatgaccatg ctgagaataa tttctcatat gtaataaaaa cctatacgaa aaatgctcat
     2641 cataaggctt actcagaatt ttattcttaa aagatttaaa atctttttct gctaaaaagt
     2701 ttttcataca aacttcaatg gattcagtca aagttttggc tgaactaatt aagtttatcg
     2761 tcaaagcatt tatctgataa taatactggt cttccgttaa tttttcacct gtactttcaa
     2821 ttaaatcatt agtaaaaatt gtgaagtgtt tgagcaaatt agttaaatta tatctaaaca
     2881 cattaaaaag tttatccaac tctataatat gacgtgttaa ttctacataa tttaaaaata
     2941 ttcttttatc agattctgtt attgtttcta ataatgaatc aatctgcctt attagctcgt
     3001 catcttgtaa attactgaca aaaaacctac tatcacttct cataattata ttctcctaat
     3061 atgatttttt caaaataatc aatatgtaac atagaagtat actctattgt tacatacctt
     3121 atttcttatt atatcagtat ttctctgtga cacataaggg tgtaacataa ttattttaaa
     3181 cgaaatgact acaagtagtc attgaagcaa atctccataa gacatttgta aaatctttta
     3241 aaaagaagcg tcgaaagaag gaacttttct tcaacgcttc ttttattgac tcaattttca
     3301 atattacttg aacgaataat ctgatttcta aactctcgaa aaacttcttg tggttgataa
     3361 tagtctggat ctatttcaaa tgtttctgag aataattcat tgaatttttc tactgaaata
     3421 atgattttac cattcttctc tcgactgttt tctattattt ctgcttctaa ttcaaataaa
     3481 tctagtgacg aactaaaatc ataaatcctg tcatattgaa taaaaaaatc aagaaaaagt
     3541 tgctcaaact cttccttatt tatcactaat gtttcaaacg gaacaacttt attttcttca
     3601 gccattcttc caatttcctc actttcattt tcaaaaatca caaaaatgat attaacttaa
     3661 aagccactaa caaaataaga cttacaaagt aaagggtaat ccaacaaaat aaccattcgc
     3721 tctacgtact acgatttggt agtcctgcct ttcaatcggt aattcataat agtaatttac
     3781 tgtttcttct ttgtcacttt caatatactc tggattatct aatatcatag catactcata
     3841 aagctcttca ccatccttat tttcaatcga ccattgttgt ggacgtattg gtttttctgt
     3901 atcattttta agtgtatagg tcacttgtaa tacacgatca tgttgtgcaa attcatttct
     3961 tttttcggtc acttcaatat ttttaaatgt tagttcaacc ccatctgcct gataagtttc
     4021 acctattttt aaatctattg ttacaatttt tattggcttt tcttctggaa aatgtctggc
     4081 tttaattgtt agataacttc caaaaagaat caatcctagt agcactaaaa gaattccttt
     4141 aacgagccac tgaaacggga agtaaacttt aaacatcttt tttctcctcc gttttgtatt
     4201 tgttttttag agaatacgat aacttttgat caatgtcatc aagcttttca attacttcat
     4261 tacttatcat tgattctagt tctgaaattt tttgttcaaa tttaatgctt tcagaatcat
     4321 taaatttatt atttgatgga ctagctaaca ctggtaaatt tgaaaccata acacgaaaca
     4381 tatttgcctt ggaaccaaaa actcctttgt tttggttgta aaaattgttg aatatttctt
     4441 tagtttcttc tgaagccgag actttaaaat atggatagtt catttttttc ttccaccttt
     4501 ctttttttgg gagggagtct gtagggagct tgctccctca gagatttacc caccatctga
     4561 cttgccagaa agtagcctag cgtgagcggg gcggattgac tggcaagtag atgggtagct
     4621 ggcgtatgtc ctaaaaactg cttctttcca agcaactctt cataggcaaa aaactggaaa
     4681 gtccactaac aagcccattc agaattccat ttcaaaattt tgttgccttt tttgctgatt
     4741 ttcaatcatt tgttgtgtga attcataatc ctttttagca cgatacattt ttacatcgtc
     4801 attcattatg cgactgattt gatagtgaat ctgtttagca gaaggtgtat gagaacaatt
     4861 ttcaaaaccc tttgccggta gaaataactc tttctgatca gtctttttaa tagaaattgt
     4921 tttacttttc gcactacgta aagtttgagg attcacatcc gtatgaagtt taatcgtgta
     4981 ttcttgatca tcttctaaag acattgtgtt tacaaaatgc ttgtctacct ctcgcaagaa
     5041 gtcatcatat ttaatgaatt tttcatcgcc ttcacggtcg ctaaattgct tttgtgcgat
     5101 ggaatctaat tccacaaaag gtacatttaa ctcaccagtt ttgtaattta ctccactaat
     5161 tagcgacata acttgctctc tttccatatt aaaaaaattt tttatatgtg attcttctaa
     5221 attcttttca agttgttcag aaacagattc aaatgaatat cttttcccta actttcttgc
     5281 actaaaagta cgttcgacat actgactttt ttcttttcta gattgtttat ctcttcctaa
     5341 agtaattaac tcacctctac gctcatagaa atttacacct tgtttgtaaa gaacatagcc
     5401 aagtttgtta tttgtttttg aaaattgata aacttcaatg ttatattctt ttgccaaatg
     5461 atccgaaaaa tcttcaaaag aattcacttc gcatttttcc aacgttgctt cgatcgcatt
     5521 ttgcacaaac tcttgataat taatttttcc atatttcatc ttagaaggat cgtttgaata
     5581 aagattggtt ctcttttcta agttttcata gtactcatta ttcactgatt caagaccatg
     5641 ttcattgagg acttgatcgt taatttttcg cattagttct aaatctttag ggtcaatacg
     5701 caacctttta catgtttcca tgttaatatt attaatgaca agatgactat gaaaatgatc
     5761 tttatcattg tgacttgcaa caatgatttg cgaatttgga aaagctttct ctgcaaattc
     5821 gacagctatt tcgtgcattt tatcaatact taactcttta gaagtactct tatcaaacga
     5881 atgaataaca tgaaacgctt gtgctatatc tttagattta ttcatcttgg tacgtactaa
     5941 attcatttct tgcagtgctt cctcactatc atcactacaa tttattcctg agactgcaac
     6001 acatttttct ttttttgaag gattagctgc atattgtaat agcgaggata aatttttctt
     6061 gcgtcctttc gatgttatag tagctcccaa agttgtttca cctcatcttt taaacttgca
     6121 ataatctgaa ttgagtgaat taaattccga tcaacttttt gggaatactc ttctttcgta
     6181 cccggtctag tttgcttttc tatccaatat tcgaaatatt ctttttctac ttctgataat
     6241 ttaaaaaaag agggggcact ccgattggac tccaaaaaaa tgtcatctgg ataactaatc
     6301 atcaactttt ttgctatgct attcgcaagt tcatctttaa aaatgttgta acggctagca
     6361 tcaaaactaa aatgtaggct cttttctttt ttatcttcag attcttctct aaaatattta
     6421 gcaatgatat ttaatgcctt taccgcttga ttcaaattgt taccaatttg atttaactgt
     6481 ttggttaaaa ctaccctatc atcttcagct aacaacggcg gttcatattt gagtcccttt
     6541 aaccgctcac ggcaaacgtc tgctctagaa attccccttt gttttgcaat caatgtcagt
     6601 tcaagataag tctttttatc gacacgaaaa tttaaggcct cactatgttt gcgatttttt
     6661 tcgtacattt tttgtttatc atccattgat tatcccctca catttttttc tagagagcaa
     6721 catttgaaat cgctctctat ttcatttttc atctttaatt cttcttgaat catcagttca
     6781 atataattag tgaccgtgat tttttcattt gttgctttct ttactgattc acataattcg
     6841 tcaagttcta agaaatcatg tgtactaatc tgtagaatta attgcatgac aatcacctct
     6901 ttatttttta agtaaactat cgaaaagtgg attaggatca ttaagtgtat ctctgaataa
     6961 ctcgttgtct tcataggtaa accttcgtct tggttttgat cccttatcat tttcacggat
     7021 ttcactatca ataatcactg tttcatgatt tgaatcaaat tttttcgctg actttctgtc
     7081 ttcaacgata ttgatttttt gtgttttttc tttcatttct ccactatctt tttgaacgtt
     7141 ctcccgaaca tctactgttt tgaatccttg actacttgta gaactttgta cattttctcg
     7201 aacatctact gtttttggtt gacttgcact gctaccttgc acattctctc ggacatccac
     7261 tgatttaaac ccttgactac ttgtagaatt ttgtacattt tctcgaacat ctactgtttt
     7321 tggttgactt gtactgctac tttgcagatt ttctcgaaca tcaattgtct tagtaccttg
     7381 agcatttgaa gaactttgta aattctctct tacatcaaca ttccgtccaa catgaccatt
     7441 cagtgaacct tgaatatttt ctcggacatc tactgatcgg ccaccatgac tacttgtaga
     7501 attttgtgga ttttctttga ctaatttttc taatcctgta tttgaatttt tagcttcttg
     7561 aattctttct ttggtcaacg cttcttttcc gtcaatatta gcgcctgtcc gcccttctac
     7621 acgtttcctt aacattattt cctcgcgatt cattgcttca ggcgtgtatt tcgcttcatg
     7681 acgcttctga ttaattaatt cttcagcaga cttagcttga ccgtgcatag catttttacg
     7741 ttcttcaata tcttgttgga ctttttgctg aattgcactt acaggattat tattcgattc
     7801 agcattattt ttcattgctt cacgcatacg ttcagaacta gacataatac tatcggcatt
     7861 ttcaacctta gcaccatctt ttctatccga aagacgtgtt ggcatggaat cagcatattt
     7921 tccagtttca tcttctttat ttttagctaa cataggtttg ctatttttat taatagcgga
     7981 cacagtacca tcatctaaac cttctttaaa cttactcttg gtatcattag ctatatcacg
     8041 catactctta aatggttttg ttgctctttc actagccatt gtagatccat ctgaagctaa
     8101 acctgataat ccacgttcat gagcataccc aagcgctttc cccgttttat tagctttttt
     8161 agaaagtgat tgtccaaagt tgcgttcagg ttttcgttct tccccttcag cttgatcgtt
     8221 tccaccatta tttttcccac ctttagaccg gttcatacca cctgttcctt tacggaatag
     8281 cattgcaccc attccaaaag cagaagcaag ttgcccatag ccttctttga gtccaatatc
     8341 cacaccaaag tatctcatga ctgttccact gcctttgatt aaaacaaaca cagcacagat
     8401 ataagcaatt gtttttataa aaatatttgc tgagatacct tcgccagtat ttaggtaatt
     8461 tatgaacatt gcaaacatag ataaaccgaa cccttgaaat ccgactgtca aatagcactg
     8521 taaaatatct gacaaaactt gttttgatcg ttgtcctgtt tctaagtcag tagcaaatac
     8581 taaaactccg agtacacgtt taaatgctaa ctcgagtatt gctgtaatta taatgaaagc
     8641 actaaaaaca tacgctaccg ctaaagcaat caatccaaaa gaaattcccc acaggttcgc
     8701 ttgatagcga taatatcctg atttgatacc atcaacaaag gttgataaaa aattatctga
     8761 aaatttagta gcaacaaatt cattatcaga attttcaact aattcataac gcagattatc
     8821 agctgttggg ttctcttttt ccattttatc aattacatta tctgtcaata cttgcgtaag
     8881 atccgttttc cagaaatttt cttttgttag attatttcgg tcatttgttt tatcaattgt
     8941 cgaatattga tctgtcttat taatataagc taaatctgtc actccctgct caatcaatga
     9001 ccatgctaca ccgccatctt gattattgat actagttgcg tcattataaa gagtctttgc
     9061 aaacattatt cctgaaagtt tttctgttga tccaatcaaa gtcggcatta aaagaattaa
     9121 tgctacagac atcactacgt tcattccaac cgattttaaa tccactgttc cttttccagt
     9181 aatcattttg taaccaacaa acatcagtga aagtatcatt aaaccaataa caactgtact
     9241 taagaccgat tgataaactt tattcattcc cgtactttca ataaagctaa acaaatctaa
     9301 cacttcggga atcatatttt gaataccatc tacaattgca aacatcgatt ttataacaga
     9361 ccaccctatc cacaatccaa actgactgta aaaatttccg ttatattttt ttaaatacga
     9421 ttgatagaca ggattattca aaaattcagt ttgactttcc gtgtcatcaa accaattgaa
     9481 aatgcttgct tggacaacat taccggtgaa aacaacgata aacattaaaa caagtatgct
     9541 caaagctaac cagtgtattt ttctactggc aatcttttct ttaactattt tcattattac
     9601 ctccctcagc ccattttctg agactctcag agagcttctg agctgttttt ctgtcaatta
     9661 tgatatgagt tacacaattg tcattttcag atcttaaatc gagaactata gtgttgaagc
     9721 aaatagtctc gattaattcg agattatctg tattttgatc tagacaccaa acttgatcta
     9781 ttaaacgatt ttcaatcaaa ataacccctc ctatattcaa agttctcaaa tgaagcggag
     9841 atacccctcc acttcatttg actcaattct attcttattg cttatctatt ccttcactga
     9901 tttgcaattc aattagttct aacgctttat tttttagaga agcaaagata taatcgtctt
     9961 tttgtttgat acggtgatct gtttttgctc ttcgtatcaa gtcacgtaaa gtcattgata
    10021 gctgttctct aacataatct acaaaatact tgttattaca gatttcatag ataattttca
    10081 gttgaatttt ttgttctttt tcagcagatt taatcgcata tttgaatttt ttataccagt
    10141 cataaaattg actgtaatcg ttattaccca ctaatttcag acagtttaca atattatccc
    10201 cccatacctg ataaagccat tctttttcaa ttaatgattc aattaatatt tcatctaatt
    10261 ttttattttc aactgaaagt gaatcaataa agtcagcatt ttgagattct ttaaaatctt
    10321 taaaatcttt agaagaatga ttaagttctt gtaaaaattt ttcacctgga agcgggaatg
    10381 acttatcacc atcgaatgtt gatttgtcgg aaggtgtatt tttttcactt ggactgtaat
    10441 gttgatttgt cggaaggtgt aaattttcct caatgcactt ttttttgtag aaatctcctt
    10501 cgctgaattc tggtttcaat aaataataaa aatttggatt attcttccca gtttttttgt
    10561 taaatccatt ttttttaatc gtaattaatt tatattcttc tagctctctc aaagcgctta
    10621 ttaccgtttt ctttgttaaa caagattttt cagctatttt ttctatagca aaaatcaaaa
    10681 aaattcttcc tttgctgtca acttttgaat tctctaaaga atattcattt tgttttttca
    10741 aatacatata aacttttttt gtactttgtt tcatcttctt atatttttta tgtttatcta
    10801 aaaaaatcgg atacttcaag tatttttcag catatacgtc atcttttgag tatgcatact
    10861 gagcaattaa tttatctatt tcttccattt attcctcttc tttctaataa atgttaaaat
    10921 gtagtcaaat aaagttttct tagaacttta ttgtcgagtg tttcctgtgg tcgccaaact
    10981 gtcgggaaca ctccttttaa tttttttcaa agtattttta tattttctat acttcatcat
    11041 tattcaaaca aacacttcct tttttctatc aaaagcacgc cacgcaactt tttatacttc
    11101 atattctttg ataaaccttg ctaattcttc ttttctaata aattgacaat ctccgattat
    11161 gcttactttt aaacctttct ctctgataaa tttttttaat gtacttctgc tacagcttaa
    11221 atacttacaa gcttccccca atctaaaaac ttctttgctt agagatgttt caattcgaac
    11281 ttgatctact gcttcttttg caactcgata gaaatatctt cgcaattctt gatctaaatc
    11341 cgatggaaga ataacttgaa tctcagattt cattttcttt gcccccacta atttgactac
    11401 atgtattcaa attcaacttt tcgtcacttt tcattaaaaa aaatttgatc aattgtgata
    11461 ttttcaattc ctttttcttt cacaagatac ttcaaaataa tcatttcttc tggagaatag
    11521 tttgttttac cgctttcttt gtttcttacc gcttgtactg aaatgccata tttttcagca
    11581 agttcagatt gtgataatcc acaaaacttt ctaaaatctt taggcttcat gactcctcac
    11641 tcctccttct tttcaacttt tcgtcactaa aagaataaca tatatttatt cataccgcaa
    11701 cgtaaaattc aacttttatc tactttttca tttcattata tgagaatgta gtgtaaactg
    11761 tagaatagaa tagatgaagg tggtgaaacc attttgtttg ataaaaacat taattctgaa
    11821 attggaaaac gaatacaaga aatacgtgtt tctttagggt atactcttga agaatttggc
    11881 gaaaatctga cacctcccgc aagcaaaagc aatgtttcta gatgggaaaa aggaaagaac
    11941 atacccaaca aagcgcggct actaagtatt gctaaacttg gtggtgtttc tactgaatat
    12001 ctactgacag gtaattctca aaaaactaag aaatatatca agtatttatt caatgagatt
    12061 ttttttgaca acggtacctt ccataacaaa ttcaaagatt tcggtaaaga cagagatagg
    12121 cttggtctat atgacttatt tttagcagta tcgaaaacat atagtctaga taaatcacct
    12181 tctttaaaag ataactttgt agaaatgatt atagatgatg tatataaaaa actcttgcaa
    12241 actgataaat cagatgacca actcatcctg ggtttcatat atatttgtct tgatgaaaaa
    12301 ctttcaaaca gacagaaaag tcttaaaagt atcaattatg aggtattcaa ttatttaggt
    12361 gttgcatttg gtttaattga tagcgaaatc aaatctacaa acgcaggtaa cgatgaagat
    12421 ttattaaatt atttaaaaga attaacatct tttattgatg aaataaaaac aactacattc
    12481 aacaaaaaaa aatattttca aaatcaatat gatatagaag aataaagatt acattttcct
    12541 atcaaaagca cgccacgcaa ctgataggag gaaaaacaat ggcaacaatt aaacaatatg
    12601 aaaagaaaga cggaaccaaa gcttggatgt ttcaaacata ccttggaatc agcccgctaa
    12661 ctggtaaaga agtccgtact acacgtagaa attttaaaac aaaaaaagaa gctcaaatag
    12721 agcttaatag actacttgta gactttgaag agaatggact taaaagggaa acgaacgaaa
    12781 ctttccaaga agtgtatgat ctctggtatg aaagctataa aactactgta aaagaagtca
    12841 ctcaattaaa aattgagatc aagtttaata aatggattct tccaaaatat gggcagttta
    12901 gaattaaaga aattactaca aaacatgttc agaagatatt gaatcagtgg gctaaaacaa
    12961 cagatcaata taaagtccta cattctaccg taagccgtat tttcaaatac gcaatgactc
    13021 tagggctgat cactaaaaat ccctgtgagc tcgtaatcat gcccaacaga aatgttgaaa
    13081 aaaagaagga tactgtcaaa atttattcac gagatcaatt agaaacctta tttcaatatt
    13141 tggaatccaa aagaagtacg tatagggcag agtacgataa aactttactg cgctttctat
    13201 tttttagtgg ctgtcgaatc agtgaggctt tagccttaga ctggtcagat attgactttg
    13261 attcaaacac cgtcactata aacaaaacct taagccaaac aaaatatggg tacaaaattt
    13321 caagtccaaa aacgagaaat agctatggtt ccctatcttt agacaataaa accattaatt
    13381 ggctaaagaa atggcaaatc aatcaaaaaa gatatatgtt aaccctcggg attactgatc
    13441 caacaatgat tttttgtgga atctacaaag aaatcattac taaacacgct atctattctc
    13501 gtatgatcac aatctgcaag aattctggta ttccatttct aggtaaccat gtaaccagac
    13561 acactcatgc tagtatgctg ttagagtcgg gagtctccat gaaggaagtt caagaacgcc
    13621 ttagacactc atcaatcaaa ttaacaatgg atacctatgc tcatctaact aaagaaacca
    13681 aagaaaaaac cgttgaaaag cttgcagagc acctaaattt ctagcggaac gtattcaatc
    13741 ccgtattcaa ttcaaaacaa aaaaaagctg aacccttatc taccaagggt tcagctatca
    13801 tttacagctt attcttcttc ttccgccatg aatgtattga atacttcttc aatcatgtcc
    13861 cattctgcgt ctgtttcgat ttgttctaac tcgccttctg ttccatcttc gttttcgatg
    13921 tatgcataag cttgtaattc tacatcttca tcttctgaaa caccagcagg atataaaaga
    13981 acatagttac gtccaaattc ttcttgtccg tcaactgtta gtaggatttc atataatgtt
    14041 tcatttcctt ggtcatccac caatgtgatg tgttcgtgtc cttcatggtc gtgggaatgg
    14101 ttatgttctg tcataagatt acctcttttc ttttattatt aaaataattg cttacctgag
    14161 ccgtctaaat aattttgtaa gatcatcaca gctgctaatt tatcgatgac tttttttcgt
    14221 ttggctcttg aagtatttgc ctgctctact agcatacgtt ctgcctgaac agtggttaat
    14281 cgttcatctt gataatcaac tggcaaggag aatagttctt tgatcttttc tccgtatgac
    14341 atggaagctt ctgcccttgg tccgatggaa ttgttcatat ttttaggtaa tccaactaca
    14401 aaccggtcta cttcatattg tgctactaat tccttcaacc gatcaaagcc aaactcttct
    14461 tctgcttcat tgatccgaat gatctctact ccttgagctg tccagccaaa ggggtcactg
    14521 atagcaacac ctactgtctt agaaccgaca tccaagccca ttactctcat aaattcactc
    14581 catgatttga gaggtagtcc ttgacaatta cttccatgat ctcatcgcgt tcgtgacggc
    14641 gaatcaaatt tcgagcatca cgataacgag gaatgtaggc cgggtctcca gaaagcaagt
    14701 agccgacaat ctgattgatt ggattgtagc ctttttcttc caaagcccga taaacaatcg
    14761 ctaatgtttc gctcacttct tttttgcgac tatcgtcaaa accaaaacgt acggtttcat
    14821 ctgtaaaacc catgattcta cacctctttc ccgcaaggta attccagctt accttctaca
    14881 accttatttt actcgaagaa agggaaaact acaaacaaat attccaaact tccgaataaa
    14941 ttaagaaaca ctatttgtat gtttttttcc ttttttctgt agctttatca aaagtactct
    15001 tttcataaag tatacgctat atttctttga atgtatgttt ttacacaatt ttttcataat
    15061 attcataaaa aattcgaata gctgctacta attttttgtt tttgttgctt gtcctgtctc
    15121 ataattgatc gtgtagccat cttgaacatt gtagataaag acattgaatt caattttttt
    15181 gtcttcaatg ctttctgctt ccaattgcac tcccctggct accagttcat tcccctcaaa
    15241 atgaggagtg acacggtagc gtacatgatg atttgtttct ttgatatatg ccgcaatatc
    15301 attttcgtga gcaagcatgt atggagcatt caacgaacgt gtccctgtca tcaagttttt
    15361 aatgttgtta ttttgaccag tcagctggaa accaattaaa tggctgcgat tatataacca
    15421 ttgcccgtca cttaatttct tttgtttcca acctgtcggg tcaatataca aaggctctct
    15481 cttttcagta gggaacaaat cttttccaag catagcattg gcttgtccta ctctgttcaa
    15541 tttatcaata tttgaatagc tttcccatgt tcctttggaa aggctaagat cctcttttgt
    15601 aaattccggc tgattcccat tgatttctat ttcttgatgt tttccatcat attctggcac
    15661 atccgctact tgagaagctt gtggtgtgga atcaaaaata gttgtaatct gctgaaagat
    15721 atctgaatct ttttgtgtgg tggaaacacc gaatgcccct gcaatcacag cagcgacgat
    15781 ccccacgatc gccttggttg tttttttgct catttcttta ctcctttact aacagctccc
    15841 taaatcttaa catatgttcc cctataaata aatactagaa agaaatagaa acagcaaaaa
    15901 ataaaacctg ttttaagatg gcttaaaaat acaaaaaaga gacggattcc tcgtctctaa
    15961 tcagtcacca ctctatctgt aaggtattta ttattattca aaaattttct tcatactcaa
    16021 gacaatacac tgatttcaca accgcttggt aaacggtgcg caaaagcttg catctgcggt
    16081 aataagtcca tccaagttaa aaacataaga agttgttttt gcttggctgt tcttattact
    16141 tgttgcagag cagctttttc acaacctatt ttaagcgggt gacgggaatc gaacccgcga
    16201 catcagcttg ggaagctggg attttaccac taaactacac ccgcaataca aaaacagtat
    16261 acgcctcttt tattccttcc tcaagttttt ttattcttta cgcttctggt atgttttgta
    16321 gtaaaataaa actaatcaat caattattgg agaagatgct atgacgggaa aagaattaga
    16381 tctgttgctg gacacttgtt tactcgctgg gaaaatcatg atggaaagca atgcggagat
    16441 gtatcgggta gaagatacga tgagtcgaat tgctttagct tctggaaatt tccgtttggt
    16501 cagctatgtc actcaaaccg gtctctttat tggtcttgat cgtacctcga ccatccgaat
    16561 ggaacaaatt accaaccgtt cgattaattt agaaaaagta gtaaaagtaa atgatctttc
    16621 acgtaaatat gttgcttcag agctaacatt agaagaactt tactgcgaac tgcaagcaat
    16681 cgaccgagac cgttctttct ttcctgtctg gttgcaaatc gttagcgcgg cagtgatcag
    16741 tggaacaatt atggtgttat ttggcggaaa gatgaccgat ttacctgtga ctttagtcat
    16801 tggaggattg ggatacgcag cttatctata tagtttgaaa ttttttagaa tcaaattttt
    16861 atcggaattt ttatcttctt tattgattgg catagccgct atctacagcg tacgttttgg
    16921 cttaggaagc aatcaggatc taatcattat cggatgtgtg atgcctttag ttcctggagt
    16981 tcaaattacg aacgctatcc gtgatttgct agctggacat tatgtctcag gagtttctcg
    17041 cggaacagaa gcgatgatga ctgctacgat gatcggtttt gcgattgctt ttattttcca
    17101 gcttttttat taggaaagga acacaagtat ggggacgata tttattcagt tttcttttag
    17161 ttttttagcg actgcggcat ttgccgttat tacaaatgta cctaggcgtt cattgatttg
    17221 ttgtggtctt tctggtgctt ttggctggat gatctactgg atctgtgttc aaataggcgg
    17281 atctgctgct tttggttcat tgcttggttc tttaggagta gcattcatca gcgatctttt
    17341 ctctaaacgt ttgaaaatgc ccgtaacgat tttcaatatt cccgggatgg ttcctctagt
    17401 ccctggtggt ttagcttatc aagcggttcg aaatctcgtt actgaatcct atcgagaagc
    17461 ggctcattat gcggtccaag caattatgat tgctggagca atcgctttag gtcttgtatt
    17521 atcagaagtc tttaaccata acatccgtaa tttcaaagta aagcgtgacg caatcatgat
    17581 gaaacgaaaa aaacggcttt ttaaataaac gaagtgtaac aaagaaaagg ttgtgaaaga
    17641 gacgttcagc cttgagcgat gacaaaatat ctcacaaaca ttgcgacaag taaccgcagg
    17701 agcaataaga agtaattatg agtattaaaa aaagttttgt aaaaatagct tctcacattt
    17761 ttacataaaa ttgacttaat actgagaaac tgacttttga acaccctcta tctgtaaaaa
    17821 aggggctgcg acatgatttt tgtcacggcc cctcttcttt attcaaattt tttccaaaac
    17881 gttcgttgat aataaacgat ccatagagcg gaaagtatta gaactaaacc gatcacagga
    17941 atattcacta accaaaatgg ataaaacaaa gccaacattc cgtataagac gataagaata
    18001 atactgatga tcaatgaacc catcatagtt gcgactaaac ccaaacttcc tgaacctctg
    18061 ttaaataatt ggttaatatt ggtccagttc agcagcagca accgataatc tctagcgaaa
    18121 taacgtagtg acaataagta gcagccgaat aaagaaccaa atagcaagct agggataaaa
    18181 aacaaaggca gctgaaaaga cagtccgctt aataatgcga tcccaccagt taaaaaactc
    18241 tgcaatatcc atccgaatct gaacttttct tttaaatatt ggttcataga gattggcaaa
    18301 gaacggataa acagaaaatt ttcttgatcc aaagaaataa gattgctgat aaaagaagtc
    18361 tgattaactg ttaagaaagc caatgcgatc cctaccagga aaacaacacc gattaactta
    18421 ttatctaaat cagttaattt tatttcgcct cctagggcaa aagcaagaat aaaaatgatt
    18481 ggagttaaca aggaagaaga aagaacttgc ataatcaaat taggttcttt tactaattga
    18541 gcattgtaac taaataaaag ctgatgcaca ttttggttct ttttatgggt tctttttatt
    18601 ttgaactcac tgtttgaatc agtcagttgc tctgtaagct ttggtactat cagctgtttt
    18661 acagcaagga aaaatcccag agccgtgata gctagtattc cccaacccaa taaaccttgt
    18721 tgagaaagtg gctgactggc agcatcatag aatggcaata atatcgaaat cggatgccga
    18781 tctgttaact cattttcaat agtccccgtt tgatgattca tccacatgat tccagcaaat
    18841 gcgatcagca tcgagctgcc aagcaagata ctagaaactg tttttctatg ttttttaaac
    18901 actgctgttc gagccaaacc aaaaacaatc aaactagcca gacaaaaaag aataatcaaa
    18961 aatagagaaa acaaaaggat tgagataatg atagtaagca aaatccctag atcagctcgc
    19021 catccggtta aaataaacat gactagaagc ggaaaaacaa aaggaatgat ggtcaaagca
    19081 actaccaaaa tctttgctga aaaaacctgt tcttgtccaa aaggcagagg caaaaatact
    19141 tgcaggtcat ttccttcaaa aaagatatta taaatgactg atatactttg agttaaacct
    19201 aacataccaa aaagtgccac gtaataagta aagaaacctg gcaatttaac aaagttcata
    19261 gcaaacatag caaatccgta aatcagtaaa aaaatcagcc ctgaaaaaag attttgagac
    19321 aaaagataga tagttaatcg ctttcccttt tttcctttct ctcttgcttt attcgtgagc
    19381 tgtggattaa catataaaag attaactcga attaattcta ataattgtcg cttatacata
    19441 cggtccatct cctgtcgctt gccttccagc cattttcaaa taaatctttt ctagcgtttc
    19501 atcaggtgag ccattcaata attcactaac tgccccctga taaatcaatt cacctttctt
    19561 caaaatagcc agtttatcgc ataactgttg tgcggtatcc aatacatgtg tagaaaaaat
    19621 gactgttttt ccttttgcgg catgagcctt catcatttct ttcaaatcaa atgctgcttg
    19681 aggatcaagt ccttgcaaag gttcatccaa tacccaaata tctggatctg gcagcaacgt
    19741 gccgatcaaa atcgtttttt gacgcattcc atgtgaaaaa cttgcgattg tttcattttg
    19801 atgactatac atatcaaaaa gcgctgtcaa ttctgctaaa cgcttttctt ttttttgtgt
    19861 gtctaattca taggcagctg aaatcaagtc ccaatattct ccagccgtca attgtaaaaa
    19921 aatatctggg gaatcaggca cataaccgat tttttgtttg atactcaatc gattttccgt
    19981 caatttcatt ccatctacta aaatcgttcc cgatgatggt tcaataatac taactaaact
    20041 tttaatcgta gttgattttc cggcaccatt atgtcctaaa aatccaaaaa tttccccttg
    20101 tcttatcgag agagacaagt cttttaatgc ttgttttttc ccgtaacttt tacttacatt
    20161 gatgaattca atcatttctg tactcctttt gtttgttatt actttttatt gtacccttcg
    20221 ttattggtgg agtaaatgtc aaaaagagtg cataacaaaa aaggatagaa acgactaggc
    20281 tgctacttgg gttgttctct tctacaggaa aacactcttc taacaggtaa gatatgagtc
    20341 tttgttttct ttaaaatgat tcattttcta tcttttcttg cataaaattc tttagtttat
    20401 caatacttct ctttcccatc tctagttgtt ctccatttgc aaatgttact atttcgttta
    20461 ctctgctaat agatgtaatg ttttcagtat taatgatata agcttttaaa tctttacata
    20521 aatactcata ttcgagtgat tttttatatt ttttaattgt gccgtttacg agaatctctt
    20581 catctttcaa tactaggcct attttatttt tataacctgg catgctcatt agataaagga
    20641 tttcatcgta atggatatag tgatcgctat taccataacg gacagttgtc cacctttttt
    20701 tcgtagcatg ttgaacagga tagttttctt tttctttcaa taagtaactt tggatgcttt
    20761 ttttattttt ttcataagtg aattctttta tcaaataacc actaggcgta atctttcgat
    20821 taataacagt tattgcttta ttcggatgag acgttagata aacaatttta cacttttcat
    20881 tcttttctct aagcatttcg cctagttcga taccgctata ataggcgttc aaatcgatgt
    20941 ctaggaaaaa atatctgagg aatagatttc attattttta atgaattcaa caaattgtat
    21001 aacgttcaat ccctgaacga tctcaaattt ccaaggactt aataaaattc tggattcttc
    21061 caaaatttct actagcattt tttcaaaaac caaactatca tccaaaataa atatacgcgt
    21121 taccataaaa agtacctcca ctcgatattt tactatcaaa atcatttcat acaacttttc
    21181 aacatacatg ttaggaataa attgtaattc tcttcacaat cttttccaac acctttgaaa
    21241 ccgatatcaa atactttcag gatgctgctt ctaaaataaa tatcaaacaa atgaatacat
    21301 catgcaaaaa aagccagaca accgacgtcc ttgcgtgtca gctgtctgag ctatgtttat
    21361 ttattttgtt cttttaaaaa gaacgataca catactgatt tttcggagca gagactttct
    21421 cagcgtttgt aacaactaca gatgggattt cacgcttgaa tggttgataa tagtctgatt
    21481 ggatggttcc ttctatttta taccattcat catttttaac cgttactcct tccggcatat
    21541 gcgtcaacaa accaaagact cctgaatctg ccacacaatg gataatgccg aatcggaaca
    21601 agaagatatc tgtattgcta tcgttcggtg tttggtaaac aaatccttca tagctgattt
    21661 ttttgccaat gaattcgcta gggtaattat aaattagctc cataacttct aaatagtttt
    21721 catctgtgat cttgatagtt tgcttatccc catacttttc tttcaactca ttcatttggt
    21781 ctaagtagtc tgatttgttg aaataaatac tggtatccgg ctttaagtat tgtgtctgca
    21841 tctccggatc ccctactgat tctttactta ctgggaaatt aaatcctttg gcttctacga
    21901 tcgtagtgtc gagactaact gttggaaaca acgtccccac gattactggc aaagctagca
    21961 gtacataagc gattccacgt tgataaggtt ttgacaaccc atggtcatga tcgtgctcgt
    22021 gtgccttttc ttctgctttt ccgtttttga cccacaaata cagctgaact aaagccaaaa
    22081 gagcagataa aatcattgaa agaatagcta agtagcgata atggacattg atatattgat
    22141 cgagtttgcc agaaacttgc aagtacatca tcaattcgaa atacccagat aaaatcaaaa
    22201 accgcagcat attttccctc ctaaataaat aatgtgaatc caataacgct aagggcaatc
    22261 agtccgatca gcgataaaat aaagcgtcct gtaaaatatc gtttcatcat cagtagattt
    22321 ttgatatcga ccattgggcc aaagaccaaa aaggcagcta caggtgctgt gccgaacaga
    22381 cttaacaaag aagatcctat aaacgcatct gcttctgagc aaagagacat cgtaaaggcc
    22441 aataacagca tgatgataat ggctaaaatc tttgttgagc cgagcgttag cataattcta
    22501 gttggtaaat aagtctgcat cgcagctgcg attaatccgc caatgatcaa ataacgacct
    22561 gtatcaaaaa attcgtcgat tgaatgtgtc aacacatgcc cagtttgatg gatcagctga
    22621 ttttttggtt cattcttctc actttgttct tcttcatgga catgatgatg gtgattttct
    22681 gctactttag acgtgatttt ttctttcaat acagcgtctt tttgaaaata ggcaagccag
    22741 acaccaatca caagggcaac aaaaaagctg cctatcaccc gccagcttgc catctgccaa
    22801 gaattgccaa atgcgataaa agtggaaaaa atcacgattg gattgatgat cggagcagtc
    22861 agcataaaag caaacgctgt gtgaactggt acgccttttt taacaaattg atgaacgatc
    22921 ggtacgatgc cgcattcaca tgaaggaaag aaaaatccta agatcgaacc agtaaaaata
    22981 gagaagatac gattttcagg aagccatctc ttcacacgtt ctggggtcaa aaatacttgt
    23041 aaggcgcctg agataagaca gcctaataat acgaaaggta atgcttcaat aacgatcgat
    23101 aagaaaatcg tactcatctg caaaaccgaa tttggaataa aagaaaacat gagtttcctc
    23161 ctttttattt ctagttcatt cgctttgcaa atatacgctt ttattcaaaa aaaacaagtt
    23221 gctctgtaaa tttttacaca actcttattt tttaccaaag cacttcaatt gactttttct
    23281 gttattccca ttaaattaag gtctcataca tatcacttct atcataaaag ggagaataaa
    23341 aatgaaacaa accactaact tgactgaagt tcaagacata ctgcaacagt catccgttgc
    23401 cgtcatttat ctttcgatgc ctaattgcag tgtttgtcac gctgttcgtc cacgactaga
    23461 ggaacttctc acacattatg atattccggc acttcatttg gatgcatttg aaacaccaga
    23521 agtagctagt aaatttgaag tgctgactgc gccagttgtc ctgatttttc atcaaggaaa
    23581 agaagtcttt cggcaagcac ggttcatcga ctttaaaaaa atccgttatc tactagatga
    23641 actgacagca gaagatgatt ccctttctta tgaagaaatc ttccgaacaa aataatcgtt
    23701 gtccaaacag aaaaaagcga ttgaacaagt gaaagttttg ccttcatttg ttcaatcgct
    23761 ttttattttt attctgctgt attttcggaa tgcgcatttg cgtcagaatg caagaaatag
    23821 atcaaggttt gcaattcatt cgtcaaatca acattttgga tcaatacatc tgacggagca
    23881 ttcaatcgag cagcggtaaa gttcaagatt cctttgattc ctgcttccgt taactgattg
    23941 actacttctt gtgctctttc agcgggtatc gttaaaattg ctacttcgat ttgttggatc
    24001 ttgatttgtt ctgacatatc ttccattgga taaacgggga taccgtctac gatgcgccca
    24061 acgatttcct cattcacatc aaaagcacaa ctgatacgta tgctattact ttgatggaat
    24121 ttgtatttta gtaaagcact tcccaagttc cctacaccga tcagcgcaac atttgtcaat
    24181 tgatcgtcgt ttaatgtctt tgcaaaaaag tgcataagat cttctacatc ataaccatac
    24241 ccacgttttc ctaattcgcc aaaataagaa aaatctcgac ggatcgttgc actatctact
    24301 tgaacggctt cacttaattc agttgaagac acttttttct ttccagcatt atttaaaatc
    24361 cttaaatagc gataatacaa aggcagtctt ttagctgtcg cctttggaat aatatgatct
    24421 ttcacgaaat gacctccacg tattgtctaa ttacatcttt gatttctcca tcatagcagt
    24481 atttatagga aaaaatcaat tccattgctc agatattgtg aaattttatt ctttattcat
    24541 ttatttatca tttctgcaaa tctcgcagta taatggaatt tatggtagac tactaattga
    24601 aaaatagttt tttatttgag gagaattcac aaagtagaaa agaggattcc atgatattat
    24661 tacaagccaa tcagattgct cgccattttg gtgcagaagt cttatttgaa aacatacatt
    24721 tagaaatcag tacaggcgct cgtgtcgctt tagttggcag aaatggcgct ggaaaatcga
    24781 ctttattaaa gatcattgct ggaattgaag cacctgatga aggaaagatc gctaaaaata
    24841 aaacagcgac tctcggatac ctcgctcagg acacaggact tgattccaat gaaacagttt
    24901 ggaacgagat gctgaaagct tttgaacaag ttagacaaat ggaagagcgg atgcgcgagc
    24961 tagagatttt cattagcgaa ggtacgccag acacacctgc ttatagttct tatttaaaag
    25021 aatacgaccg gctgcaacac gatttttcag atcgaaacgg ctatggttat gaaaatgaaa
    25081 ttcgttccgt attgcatggg tttaaattcg attcttcatt ttatgatcag aaaatcgata
    25141 ctttatcagg cggacagcgc acacgtttag ctttagctcg catgcttttg caacaccctg
    25201 acattttgat tctagatgaa ccaacgaacc atttagatat cgagacactt tcctggcttg
    25261 agaattatct gcaaagctat actggtgcat tattgattgt ttcccatgac cgttattttt
    25321 tagataaagt agtcaatgaa gtctatgaat taagcagaag aaaaatgcgc cattacaaag
    25381 gtaactattc gaaatatcta gatttgaaag cagaacagtt agcaagtgaa tggaaggctt
    25441 atgaaaagca gcaaacagaa atccataaat tagaagactt cgttgctcgg aaccttgttc
    25501 gcgcctctac cacaaaacga gcgcaaagcc gcagaaagac attagaaaaa atggaccggc
    25561 tggatcgtcc tcaaggggat gaaaaacaag caaactttct attcagtata gaaaagcctt
    25621 ctggaaatgt agtcttgcaa atcgaagatg ccgctatcgg atatgataat gtcaccttat
    25681 ctgaaccaat caatctagat atccgtcgtc aagaagcgat tgctctagta ggtccgaatg
    25741 gtatcgggaa atcgacgttg ctgaaatcaa tcattcacca gatccctttt atccgtggaa
    25801 aagaaacgct agggacaaat gtcaccatcg gctattacga tcaaggtcaa gctgatctgc
    25861 atacaaacaa gacgatccta gcagaattgt gggatgagca tcctaccact ccagaaaaag
    25921 agatccgaag tgctttaggt gctttcttat tttctggcga agatgtagaa aaaccaatcc
    25981 ctctgctaag tggcggtgaa aaagcacggg ttgctttagc caagttagcg atgaacaaag
    26041 aaaatttttt gattttggat gaaccaacaa accatttaga tattgacaac aaagaagtat
    26101 tagaaaatgc attgatcgat tatgacggca cactgctttt tgtttcccat gaccgatatt
    26161 tcatcaatcg gatcgcgaca aaagtcgtcg aactctctga aaatggcagc aaagtctatc
    26221 taggagacta tgattattat ttagagaaaa agcaggaaga agaagaaatc gccgaattgt
    26281 tggcacaaga tgagccagaa tctgctcctg ctcccacgaa caaatctgat tattaccaaa
    26341 gcaaagaaca gcaaaagctt atccgtagcc ttcaacgaaa aattactcag gttgaagaag
    26401 aaatggcgcg gatcgatgaa tggatcgatc agttggaaca agaaatggtc gcgccagaaa
    26461 acctggaaga tcacgtaaaa ctcaatgagc tgaaccaaga tttagaagct gctagacaag
    26521 atcaagaaac aaaattgacg gaatgggaag aactaagctt ggaattagaa gaatatgaaa
    26581 attaacgaaa aaaccaaaac agaaaccatt catgctgttt tggtttttct ttttttattt
    26641 tatcaaacaa aaattccata tttacctttt tcaccaataa gaagaccaat tactagtcat
    26701 tctcactaaa gcttctaaat aatagtaatc accccaaata caaggtgtat ttaccccatt
    26761 atttttgggc ttattataaa cagactgtgt taaaaagcca tcttcttctt ccgttgtagc
    26821 atatctttct ttcaattgtc gcataatttt ccaaacagca gactggtata agttcttttc
    26881 tgttttgtct aatagacctg attctattaa ttctaataat ccacaaacca tgatcaccat
    26941 actagatgta tctttttctt ctctgctaga atcatcaaag atcaaatccc aataacaaat
    27001 ggtatcttct ggcaaccgat tcataaaata attggctaat attttgctta aatcaaaata
    27061 tttttgttct ttcaaataac gataacttaa tgcaaaaccg taaatccccc atgcttggcc
    27121 tctagcccaa caggaattat cactataacc ttgatgcgta cttccatatc ttggttttcc
    27181 atctttgaca tccatataaa atgtatgata agttgaacca tcttctctta ctaaataatc
    27241 tgctgcattt tgaatatgag cctgagcagc ttttttatat ttttgatttc cagtttcttc
    27301 actcgcccaa tacaataatg gaagattcat gcaacaatcc atgatcattc taccttgttg
    27361 tgaaggatca ctaggatctc cccaagcttg tataactcct gccttctccc aaaaacgctg
    27421 aagtaatgtt tctgcagcat caattgaagc ttccttcatt tttcgatttc ccgttatttt
    27481 ataatctgct acggttgata aagaatacaa aaaaccaaga tcgtgatgat tagtgataat
    27541 ttgacagtca atcctgtgga taaaatctat atctgctttt tcagctgttt gttgaaataa
    27601 aggatcaccc gtcttctcaa ataacaacca attaattcct gtccaaaatc cttctgtcca
    27661 accaatattg tctcttaatg gataacgtcc ttttatagga cactcgcttg ggaattgata
    27721 ctgactgtta ctgatacgtt tgattaacct ctccgtgtgt ctgcgacaac gctcgatctc
    27781 attattccat tctttttcca ttaattcttt ataacattca tttatccatt tttctggatg
    27841 tattatctct tcaaacatca ctttatcaag catttcccca ccagccttta gcataatttt
    27901 agtctttttt tattgttttt attttggata gttagcccgg ttgtcccatc aaaatcaatt
    27961 ttgggacgat tgttccatac ttctaaacta taatcccgat cttgatgagc aaccactcct
    28021 gttccgagcc aatgggttcc ttttccaaat gtaccctcta atccaggaat aaaagtgttt
    28081 tcccatgtca tcaagtttgt attgggcaaa cccataatag ctgtggattt tcgtttaata
    28141 gtatcgtcac ttaaacagat aatacctgaa aagccagctt cactcaccct atagttttcc
    28201 ttgtcttctt ctatgattat tccttctttc tcaggagaac attcaatagc aaaccctgtc
    28261 tcatatagaa catattctgt atctaattct actttgtgta cgcgaatctg ccagccttca
    28321 aaaggaataa gccaagttct gatttttgcc tgtaaagtag gttcccatgt agaggcaagt
    28381 acctctttct tacatacaat gtctcgtaca ttatttcgaa cgatgaactg tccataggtt
    28441 ttgatgctct cattcttaaa actggtcgtg atatatgtgt ccgctcgctg aatccctagc
    28501 attgaatcca ttgccatttc tgctttcaat tgattcgctc gcggtatcga aaaaccaaat
    28561 tgactagaat aagcaaattt taaatatttt tcattggtca atgtatggaa atttggccct
    28621 aattgtcccg cattcaaaaa aaatgtatgt ccattatcat gttgtatgag caaattggct
    28681 tctgaaagaa gtttagttcc ttcacgaata ggcataggca tttctttagc cgtccaatac
    28741 tcatggtctt caggtagcgc caacaataaa aaaatcttat tcagccataa tggagataac
    28801 gtactattat agggttcagt caatgtcaat tgagggtagg tataaccaat attcaggata
    28861 cctttttcat caaatatttc tttttgcatc caccatctta tattccgatt gactaacccc
    28921 ttgatttcac ctaatttaaa aggcaaaaga tcggcccaca acatagctga ccaaaagctt
    28981 gaaactgcaa aacgataaat catgcttcga ccaaaaggca catttgcacc atcttccgca
    29041 aaaaaatgaa tatagtctct agaaaaatca atagctcggt tcttatatat ctggctaatg
    29101 ggcttttctg gttctagtac gctataaatc aaaccataat aatgaaatgc aaaaggatta
    29161 taataatctt ggcgacctct tgaactgtct cgataccagc cattttgaag ataacaattt
    29221 tctatattat caaatgcttc tttcagtgct gattctttaa ctggataacc aaatttttgg
    29281 ataattgttc cgacaattat cttaaaaaat tgccaattac catctgcaca ttcatattca
    29341 aaaatttgcg agaaccaatg aataatctgg cttttttctc ctgtatctaa ttttttccat
    29401 aataattgtt catgatgata taacgctaat aacattgcgg gcatttctac catacgctgg
    29461 tctctttcat gtatttctcc ccaataatcg ggatgggaag gatctgttcc agcttttatt
    29521 cctgatagaa ttaatttcaa ccatcgttca tctaattggt caattgcggg ccccgctccc
    29581 cataaaaccc gagagaatcc ttccattcct gcaattttat ttccatatcc taccccttga
    29641 tgtatataat caatttgtgc gccacttgct cgataaaacg gctggagtgg ttgatttatc
    29701 tttttaaata agtcaaagta atcctgtctg gtccttaata gtggtactgg atgtttcatt
    29761 gtattttctc ctctttttac taccaaatag ctaattccga ctgttctaat cgaagtaagc
    29821 cttcaataaa aaaataatca gaatagatca gtggcacatt ataagtcagt tctctatggt
    29881 atgcttctgc tccgcctcca atgatcccat cttcatccat attccaattt gcatagtgct
    29941 tttctgtctt ttggagtata ttgatagcag cttcatgata catttttgat cgtacagagg
    30001 aaacatatcc tgctaattcc agaagaccgc atgcagcgca tactccagca ctggtatcaa
    30061 tattcgaatc ttttacagca aaatcaatga gaggaatata accagttttt tcgattttct
    30121 gaataaaatt tactgctatc ttttctgcta tagctagata gtacggattt tttgtgtaac
    30181 gataacttaa cgcgaatcca tataaagccc atgcatttcc tctgctccaa caagaattct
    30241 cattgtatcc ttgcccgcca agtaaccgaa tatatttccc tgattctgca tcaaattctg
    30301 cgatatgccc ggttgatcca tctttcctca ctagatactt agctgttgta tctgcatgct
    30361 gccgagcaat tttagagaac ctcggatcac cagtttccct cgaagcccaa tacagtaatg
    30421 gtaaattcat catactatca ataatcatcc aaccaggttt atggtcattc catgctacta
    30481 aatagttccc tgaaatatta tagcgtccag caagtaccgt agctgcatgt aaccctagtt
    30541 gtcgactatg tttgttttga gactgttgat aatgtgcaat agccgatggt aagaataaaa
    30601 aacctacatc atgatgaacg tctgaaaaat ggtacagggc agattctaat aattgttctt
    30661 gttgtattgc tgcctctttg aacttttctc gttttgtctt gtgaaagagc tgccataaaa
    30721 taccactcca aaaaccattg gtccaccagt cgattcctct gtcctttatt acgtctgtat
    30781 attttccgtt gtaagaaata tatggaattt tattccccat tctgtctaat tccgcatcta
    30841 tcttttcaga agctacattc aaaatttttc ttgaccattc cttcgtctgt tcattcatgg
    30901 atatcccgcc attcttttaa tttttatgaa tgtggagttg ctcctagaac gaactagatg
    30961 gttaacattc gttatttttt ttacttattt gcagctccaa tgtcattctc cttaaattta
    31021 gactgcgccc acacataaat caagaccatt gggatcactg aagttgctaa aattagcata
    31081 attgcgccat aattaattgg ctcacctgta ctagaaaccg tcatattttt gataattaag
    31141 ggaaccgtat atttatcttt atctgaaagc atgactaatg gaaatagata ttgattccaa
    31201 cttcccataa agataagtaa accactagta ataatcgtag gtgataaaat cggtacagcg
    31261 attttcgtaa aaatcaccca ctcattggca ccatcgattc tggcagcctc catcagtgct
    31321 gtaggaaatt gactgctata ttgtcgcatc ataaacactg aagttgtact ggcaatcgaa
    31381 gggatgatca cacctgcata agtattcgat aatcctaaac gactcataat gtaaaataaa
    31441 ggaatcaatg tggtaaaaaa aggcaccatc ctagatagca taactgtatt gaacaacagt
    31501 ttattcccca taaaacgata ctttgctaat gcataacccg ccattgtaga actggctgta
    31561 gctaaaactg tactgattac agcaataaca atcgaattcc aaataatcaa gggataatta
    31621 tatctcgcca tgatggcttg ccagtttttt aatagcatat ccccaaactt gaaattgatt
    31681 ccgccactta aaatttcttg attactttgc gttgaagcta caatcatata taaatatggc
    31741 atcaaaaata ttaaggcacc aaacacaata atgacgtacg taaaaattct gctttgtatc
    31801 ttttgtttag tcatttttat cacctccgaa tttaaattga atagccgata atataacaga
    31861 tacaaacacc atcgtccagg caatagcaga ggcttttcca aaatcaacca tttcaaaact
    31921 tgttttatat aaattgactc ctacgaccaa agctgaattt tctggtccat tggaagtccc
    31981 aaagaatata tttgggatat tgaaattacc caagccattg atagtggcta aaactgtggc
    32041 cattaaaatg attggcttta gcatggggat cgttaataaa aagaattgcc gaaatttcga
    32101 tgctccatct atttcagcac tttcgtatat ctctttagaa atcccttgaa gaccagctaa
    32161 aaataaaata gtgttatatc ctacactaag ccaaatcatc gtgatgatca ttgatattcg
    32221 tatccaaaaa ggatttgtta accactgtac accgttaatt cctagcgcat tcaaaaatcc
    32281 attgaataac ccagtcggat tgaaaaaagt catgaatacg gaagctacag ccaccgttga
    32341 tgtaatggtt ggaatataat agacagttct aaaaaatcct tttcctttta actgtgctga
    32401 attcaataaa acagcaaagt aaatagctaa tagcatcgtt attggaattg atcctgccat
    32461 gataatcaaa acattcgtgt aagatttaat aaacaatgga tctcggaaga tagctagata
    32521 attgtcaaat ccaacaaatt caaatgagta gccaattttc ataaaactaa aagcaaacga
    32581 gataatgatg ggaatcaaaa tcgtcacaat aaagaaaata acaaaaggtg tgaccaatcc
    32641 ataagcactt tttttatgag acgtatctgt tgcttttttc ttgctgttct ttattgtctt
    32701 gcttggtaac gaagattgta tcatcgttaa gtcctcctaa tattttttaa tcaccagtta
    32761 attttacgcc gtacttatga gcaaaatttt ctgcttcttt tagatatgaa ttttcaaaat
    32821 cacctgtttg ccaatagtta tatgcagcgg tagtcaaata agacgtagca tctgaataag
    32881 tggctggtaa aacagtattt gatgtatttt cattgatttt attcaatagt tcatagtatt
    32941 tttgtcctcc ttagtagtca aactttttct cagctgcttc tgtttgatag gccaatgagt
    33001 tagatgtagc cacgcccagc tccagtgcgt tggctaagca ttcttcatct gtcagcataa
    33061 atgtaagaaa ttgttgtgcc acttgtggat ttttggcatc tttagggaca taaaaacttg
    33121 atcctcctga tactgcacct tttcctggat tttcttttga aaaaggaatc agtggagcca
    33181 tgcgccattt gtcagatgca tcaggaaaat tcaaagacat attcgtagca taccagccgc
    33241 cagcaacaaa cattgcagat tcttgaaatg ctttctcagc atcttgtgca ccgtagaaat
    33301 gtacaatatc tgagtcgatc atttctttga ttaactttgc agcatgtttc gcttctttag
    33361 tattcagacg gatatttcct tcttcatcaa gcaaagattg attctgctgg gctagcatgt
    33421 tgataaacaa ttcttggtcc ccagattctg gcaaggcaat tccaaaacta ccagtttttt
    33481 cttttaatgc ttttgccacc tggatatatt cttcccaaga actgatttct tcaaaatcta
    33541 cacctatttc agcaaatttt tttggttgat aataacaaag tgctggggta aaatcactag
    33601 cccaaggaat aatcgtttca ttactcgttt gttgacgcaa aatattcaat ttttgatcat
    33661 aaaactgatc gccatatttg tcataaaatc catattcatc agcactataa aaagcatctt
    33721 gaaatttttc cagcacacct gctgctgaag tgtctgccat ggagataata tccggcatat
    33781 cttcgtgtgt taccaatttt ggggtgatca tttgtactgt tgctgttccc gaagctacat
    33841 tcacaatttt taagtcaata tttgctccag ttttgcggtt atagattttt gcagcatttt
    33901 caacatagtt tgtcagtttg ccgtttgcga catatacttc taatgtagtg gcttttttta
    33961 tcattggatc tgcgatgttt gctgttactt cttcgttagt ttttccacat gcacttaagc
    34021 tgaataatag ggtaatgttt agcaaagcta tcaccaattt gtatcttttt ttcatgtcta
    34081 tcccttcttt cttttcaagt tcttatataa aacgctttca cttatgtata ttaacggaat
    34141 tagtaacaca aatatttata taaaaaaata ttttacttgt cgttttggct tttcattttt
    34201 gttataatag tcattaatta taaatagaaa gctttttata taaaaagaga aaggaaagtg
    34261 gttcttttgt taacaaacaa ccaatcctcc aatcttgtca aaaaaacact aacctattcc
    34321 atagataccc atcttcattt atctgctgct ccctattttc gactactaat aaatgaaagc
    34381 gctaatttat atgctgaatt tgcacataaa tctatagaac tagataatcc ttccctttta
    34441 ttcattgata aacagcaaga agtccaaatc ttttctactc aaaaggaaac acaaactttt
    34501 atcattatcc agttttattt tgatgagcaa ttattagcac atattacggg acaatctttt
    34561 tctatagatc aagaaataac atctatcatt acttttctga aaaatgaaca gttcaaaatt
    34621 gattatctaa aacatagtaa gccagctatt tcctatgatc aggaaatcaa ttcttttttc
    34681 atactatgcc aacagatgag cattcatttg ctttccttat tagttactta ttgtctgcaa
    34741 aaaattcaat tgtcttcctt accaaggcat tatcaacagg aacttgcttt attgacaata
    34801 ccttcaaatg agaaagtcat tcctaaaaaa aagcatattc tttattcaga tgaattagtt
    34861 gatccaatca tacgatattt agaagaacat ctttcagaaa attttttgct tgaacaatta
    34921 gcccaaattt tttttatcag tccagccagc ttaaaaaaac attttagaaa agtgaatgga
    34981 aaaagtgtta ttagctattt taaagaacta aaaatggaaa aagcaaaacg tctcgtgcta
    35041 gaaaatgaat taacctatac agaaattgca gatatattag gatttcattc gatccatcat
    35101 ttttcttcag cttttaaaaa atatacaggg ttatcccctt caaagtatta tctatcctta
    35161 aaatagaaaa aaatttttag gttttatcca caaattattt ctctatattt tctgtctatt
    35221 caaaataaac aataattttc cggcacaatt atttgctgtt ttttaccata acatagtacg
    35281 atcaacgtag aaaaggagat gtttttatga aagttgttgt cattggcggt gtagctggcg
    35341 gtccttcatt tgccactcgt ttccgtcgat tgaatgaagc gcacgaaatc attatctatg
    35401 aacgcggaga aaatatttct tatgcaagtt gtgctttgcc ttattattta ggaggtgtga
    35461 tcactgaccg tgactcgctg atcgaacgta caccagaaat attgaaaaca aaaaacaaca
    35521 tcgatgtctt tactaaacac gaagtaacag caatcgatcc ttctactaag cgattaacag
    35581 ttaaagacct atccacaaat gaagaaataa aaacagatta cgataagttg atcatctctt
    35641 ctggtgctag accagattat ccggatattc ccggagtttt tgaagcagaa aacggctttg
    35701 tcctccgtag tgtgacggat gcggatcgaa tcaaatcgtt ccttgaagaa aaaaatccac
    35761 aacatgtcgt cattcttggt gcaggtgtta tgggtctgga attagctgag aatttcaagc
    35821 atcgcggctt agacgtgact ttaatcgatc aattgccaca agtcgctttc ccttatgatc
    35881 cagaaattgc taatttagtt tatgacaaat tgctgaaaga aggattagcc gttcatttag
    35941 aaacaagagt tactgagatc cgtgataaag gtcgagaaat agtattatca gatggctccg
    36001 tcctttctgc tgatatgcta atttttgctg ttggtgtttc tccgaagaat gaagtggtga
    36061 aagcaaccgg catacaatta tcagatacag gtcagatcat tgttgatgac cagttacaaa
    36121 ccaatctgcc ggacatctat gcgattggcg atattatcga aacgactagt gtagtgactg
    36181 gtcagccgat ccaaagtatg ctttccagtg cggccaatcg tcaaggacat atgctggcag
    36241 atattttaaa tggtacgcct atgcgctatc gcggatatat tggtgcaggt gtcgcaaaaa
    36301 tctttgatca tacagcaagt tatgcgggaa tgacagaaca tgaattaaaa gcatcaggca
    36361 taacaaatta taaaactgtt tttatcactc cctttgacca tgcctatttc tatccagaag
    36421 ctacaagatt aaatctaaag ctgatttttg atgcagatag cggtcgtatt ttaggtggac
    36481 aagcatttgg agaaaaaggt gtcgataaac ggatgggaga actttctgta gcaatcaccg
    36541 gaaacttgac agtctttgat ttgcctgatt tggagttgcc ttactctcca ccgtattcta
    36601 ctacccgtga cccgttgaat atagctggtt atgtcgcaat caatcaaatg acgaatatcg
    36661 tagaaacgat caaagcaagt gatatacccg aaaacgattt gaaagaagcg ttctttttag
    36721 atatacgtga acctaataaa gcaccttctg gcagtatctc ggcaacaaaa aatattccaa
    36781 tgaatgagtt acgagatcga atcaatgaaa tcccaaaaga taaaaaagtt tacattactt
    36841 tcagaagagg attgaatact tatacttctg cccgaatctt ggcaggtttg ggtatcaaag
    36901 cgattttgat tgaagaataa aaaaacgacc gcggtgggta gccgcggtct aggagttatt
    36961 tttacttgag gagtaaaaat gaaaaagtat atagggttgt tggttggtat gtatatagaa
    37021 tagaagataa atgtgaagaa attgtgcatt atttcttcac atttattagg ttatagttta
    37081 agaaagttta aacattgcgc aatttaatta ttttagctgt ttcttttcat aaaaaaacat
    37141 gttgtgactc tgagacaaat catagtccat agtgatgtct ctagagtaac tacgcctaat
    37201 attacgaggc atcatattaa tctatcagca ctagtaccta aactagcatc cctttcgaat
    37261 attttttctt atataataaa gtttgctttc actcctctaa tctcaccaaa tcgactggct
    37321 tgcgttgtgt gatactagga actgattggt ttagaacgac ttttctattg taatcatatt
    37381 tttcgccatc ctcgttgtct tctaatcctt caatgaatga tccctaatgt gtgtattaaa
    37441 taatttaatt tttttgttcc tatttattta aca
//
LOCUS       DAYNVV010000024        36570 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.024, whole genome shotgun sequence.
ACCESSION   DAYNVV010000024 DAYNVV010000000
VERSION     DAYNVV010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.024"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(27..1523)
                     /gene="lysS"
                     /locus_tag="ACGXWR_001348"
     CDS             complement(27..1523)
                     /gene="lysS"
                     /locus_tag="ACGXWR_001348"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFK0802929.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1634..2638)
                     /gene="dusB"
                     /locus_tag="ACGXWR_001349"
     CDS             complement(1634..2638)
                     /gene="dusB"
                     /locus_tag="ACGXWR_001349"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HFK0802930.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2639..3526)
                     /gene="hslO"
                     /locus_tag="ACGXWR_001350"
     CDS             complement(2639..3526)
                     /gene="hslO"
                     /locus_tag="ACGXWR_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HFK0802931.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3743..5854)
                     /gene="ftsH"
                     /locus_tag="ACGXWR_001351"
     CDS             complement(3743..5854)
                     /gene="ftsH"
                     /locus_tag="ACGXWR_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFK0802932.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5944..6489)
                     /gene="hpt"
                     /locus_tag="ACGXWR_001352"
     CDS             complement(5944..6489)
                     /gene="hpt"
                     /locus_tag="ACGXWR_001352"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HFK0802933.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6489..7934)
                     /gene="tilS"
                     /locus_tag="ACGXWR_001353"
     CDS             complement(6489..7934)
                     /gene="tilS"
                     /locus_tag="ACGXWR_001353"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HFK0802934.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8054..8524)
                     /locus_tag="ACGXWR_001354"
     CDS             complement(8054..8524)
                     /locus_tag="ACGXWR_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 domain-containing RNA-binding protein"
                     /protein_id="HFK0802935.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8570..8995)
                     /locus_tag="ACGXWR_001355"
     CDS             complement(8570..8995)
                     /locus_tag="ACGXWR_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HFK0802936.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9062..9331)
                     /locus_tag="ACGXWR_001356"
     CDS             complement(9062..9331)
                     /locus_tag="ACGXWR_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFK0802937.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9342..10937)
                     /locus_tag="ACGXWR_001357"
     CDS             complement(9342..10937)
                     /locus_tag="ACGXWR_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFK0802938.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10952..14473)
                     /gene="mfd"
                     /locus_tag="ACGXWR_001358"
     CDS             complement(10952..14473)
                     /gene="mfd"
                     /locus_tag="ACGXWR_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFK0802939.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14490..15050)
                     /gene="pth"
                     /locus_tag="ACGXWR_001359"
     CDS             complement(14490..15050)
                     /gene="pth"
                     /locus_tag="ACGXWR_001359"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFK0802940.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15403..16377
                     /locus_tag="ACGXWR_001360"
     CDS             15403..16377
                     /locus_tag="ACGXWR_001360"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFK0802941.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16547..17947
                     /locus_tag="ACGXWR_001361"
     CDS             16547..17947
                     /locus_tag="ACGXWR_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HFK0802942.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18025..18747)
                     /locus_tag="ACGXWR_001362"
     CDS             complement(18025..18747)
                     /locus_tag="ACGXWR_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFK0802943.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18826..19332)
                     /locus_tag="ACGXWR_001363"
     CDS             complement(18826..19332)
                     /locus_tag="ACGXWR_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFK0802944.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19455..21254
                     /locus_tag="ACGXWR_001364"
     CDS             19455..21254
                     /locus_tag="ACGXWR_001364"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HFK0802945.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21322..22896)
                     /locus_tag="ACGXWR_001365"
     CDS             complement(21322..22896)
                     /locus_tag="ACGXWR_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFK0802946.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23151..23660)
                     /gene="mreD"
                     /locus_tag="ACGXWR_001366"
     CDS             complement(23151..23660)
                     /gene="mreD"
                     /locus_tag="ACGXWR_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HFK0802947.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23664..24518)
                     /gene="mreC"
                     /locus_tag="ACGXWR_001367"
     CDS             complement(23664..24518)
                     /gene="mreC"
                     /locus_tag="ACGXWR_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HFK0802948.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24673..25311)
                     /locus_tag="ACGXWR_001368"
     CDS             complement(24673..25311)
                     /locus_tag="ACGXWR_001368"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HFK0802949.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25312..25962)
                     /gene="rpe"
                     /locus_tag="ACGXWR_001369"
     CDS             complement(25312..25962)
                     /gene="rpe"
                     /locus_tag="ACGXWR_001369"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFK0802950.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25975..26874)
                     /gene="rsgA"
                     /locus_tag="ACGXWR_001370"
     CDS             complement(25975..26874)
                     /gene="rsgA"
                     /locus_tag="ACGXWR_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFK0802951.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27039..29108)
                     /gene="pknB"
                     /locus_tag="ACGXWR_001371"
     CDS             complement(27039..29108)
                     /gene="pknB"
                     /locus_tag="ACGXWR_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HFK0802952.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29105..29845)
                     /locus_tag="ACGXWR_001372"
     CDS             complement(29105..29845)
                     /locus_tag="ACGXWR_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HFK0802953.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29858..31216)
                     /gene="rsmB"
                     /locus_tag="ACGXWR_001373"
     CDS             complement(29858..31216)
                     /gene="rsmB"
                     /locus_tag="ACGXWR_001373"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HFK0802954.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31216..32154)
                     /gene="fmt"
                     /locus_tag="ACGXWR_001374"
     CDS             complement(31216..32154)
                     /gene="fmt"
                     /locus_tag="ACGXWR_001374"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HFK0802955.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32147..32638)
                     /gene="def"
                     /locus_tag="ACGXWR_001375"
     CDS             complement(32147..32638)
                     /gene="def"
                     /locus_tag="ACGXWR_001375"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFK0802956.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32653..35061)
                     /gene="priA"
                     /locus_tag="ACGXWR_001376"
     CDS             complement(32653..35061)
                     /gene="priA"
                     /locus_tag="ACGXWR_001376"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HFK0802957.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35314..35619)
                     /gene="rpoZ"
                     /locus_tag="ACGXWR_001377"
     CDS             complement(35314..35619)
                     /gene="rpoZ"
                     /locus_tag="ACGXWR_001377"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFK0802958.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35624..36238)
                     /gene="gmk"
                     /locus_tag="ACGXWR_001378"
     CDS             complement(35624..36238)
                     /gene="gmk"
                     /locus_tag="ACGXWR_001378"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFK0802959.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
BASE COUNT         9886 a         7989 c         6707 g        11988 t
ORIGIN      
        1 gaattcctta gacagctttt attcgattat ctcattgttg ggaatagcaa aacatcccga
       61 attgattgtg catcagttag caacattact aatctgtcga tcccgatgcc tagaccacca
      121 gttggcggca taccgtattc taaggcttcc aagaagtctt cgtctacacc gtgagcttcg
      181 tcatttccta gttcacgttc tttttcttgc gcttcgaatc tttctctttg atcaattgga
      241 tcgttcagtt ctgtaaaggc attagcaaat tcgcgcccca ctatgaatag ttcgaatcga
      301 tctgtgaatc gaggatcttc tggatttttc ttcgctaaag gcgaaacttc gactggatgt
      361 ccgtatacaa acgtcggttg tgtcaatgtt tcttcaacaa atgtttcaaa gaattcattg
      421 ataacatgtc cgacacccat agcttcggtt acttctacat tgtgtttttc ggctaaagct
      481 aatgcttctt ccaatgtcat ttcttgccag aagtctacac cagtttgttc tttgattgca
      541 tctaccatat ggatgcgttt aaagtcactt tctaagtcga cagcttgtcc atcatatgtg
      601 atttttgctg ttcctagtac tttttcagct gcgttacgga taataccttc tgtcagattc
      661 attacatcat tgaaatcagt atatgctgtg tatgcttcta acatcgtaaa ttctggatta
      721 tgtgtagtat caattccttc attacggaaa acgcggccga tttcataaac tttttccatt
      781 ccgccaacaa ttagtcgttt taaatgaagt tctagcgcaa tacgcaaata taaatcaatg
      841 tccagtgcat tatgatgcgt gataaatggg cgtgcggcag ctccacctgc ctcattgtgc
      901 aatactggtg tttctacttc aatatagcca ttgccatcta aatagcgacg gatttcgctg
      961 ataatttggc ttcgtttcat aaatcggtca aagctttcgc gattactgat taaatccaag
     1021 tagcgttgtc tgtagcgttg ttcaatattc gttaagccat ggtatttatc tggcagtgga
     1081 cgaagtgctt ttgacaaaat cgtgatttct gaagctttga tagaaacttc gcctgtgtct
     1141 gttttcatga tttgtccagt tacaccaaag aaatctccaa ggtctgcatg tttgaatact
     1201 tcataggcct catcacctac ttggtctttt cttacataaa tttgaatttg gccttcacga
     1261 tcttgtagat gcgcaaatcc agttttccct tttcctcggc gagtcatcat acgaccagct
     1321 acactagcgg tcaatcccat ttctgctagt tcttcttttg ttcttggatc aaatagttca
     1381 tgcaattctt ctgagttgtg cgtgcgttca aatcgttttc caaatggatc gattccatct
     1441 tcacgcaatt gttccatttt ttgacgacgt acaagcattt gatcatttaa atcttctact
     1501 tgatgttgtt gttcctgtgt cacaaaagtt cctccattct catgttaatc tctttcctat
     1561 aatgccaatg aaacacaaaa aaagcaagcc gaacttggaa tttcggcttg aaaattcacg
     1621 aaaaacttag aaatcacaac gtttgtttca atagtacttt ttccgctttt tctacaaatt
     1681 gatccagcag gtcattgatt tcttgctgtt tttctgtctg attgattgct actttcactt
     1741 tcgctgctcg aggaatccct tttaaataat aagccgcatg tgttctgaat tctctacaag
     1801 ctactttttc tcctttgaga tctgctaagc gttgtaaatg aagtttagct gtagcaattt
     1861 tttcggctgg tgttggttca ggaatcagtt ctcctgtttc gagataatgc tgtgtgcggt
     1921 gaatcatcca tggattgccc agcgctgcac gaccaatcat cacaccgtct gcaccgacat
     1981 agtcaagcat ccattttgca tcttctggcg ttttgacatc cccgttcccc ataaatggga
     2041 tcgtcaaatg ttttttcact tctttcaata cttcccagtc cgcttttcct tcatacatct
     2101 gaacccgtgt acgtccatgc atagcgatgg cacttgctcc agctgattgt gctgctaatg
     2161 cattttctac agcaaagacg tgctcttcat cccaaccaat acgcatcttg attgttactg
     2221 ggatatttac tgctgaagaa acagcttgga ccatttcgta tactttctca ggatctaaaa
     2281 gccattttgc tcctgcttct gctttgatta ctttatttac tggacagccc atattgatat
     2341 ctattatatc ggcagctgtg ttttcttcga caaattgagc agcttcaact agactatctt
     2401 tatttccgcc aaatatctgt aaacttaatg gatgttctgt ttcttcaatg tggagcatct
     2461 ctaaagtttt tttgtttctg aaatgaatac cttggtcact gatcatttca catacgacta
     2521 agcccgcacc aaattctttg acagtgactc gaaatgctga atttgttatt ccagccatcg
     2581 gtgcaacaac gacacgatta gggatttcca cattgccaat tttccatgtg tgttccactt
     2641 aaatccctcc taaggcttct ttcttcaatc catctaattc ttcttcgcta tacttgtatt
     2701 tgttattaca gaaagaacaa accgcttctg caccgtgatc ttcgtctatc attgcttgga
     2761 tttcttctgc acctaacgcg ataattgctt ctgcaaattt ttcttttgaa cagtcacatt
     2821 tgaattgaac aggcattttt tccaaaatgt tcaattcttc tgtaccaagc aatcctttca
     2881 atatttcttc tggtgtctgt ccttcatcta agagggtaga gattcttggt gtcgttttta
     2941 attgttcttc gatcttgctg attgtttctt catcggcacc tggcatgatt tggatcatga
     3001 atcctcccgc cgtcttgatg ctgtcgtcag tattgaccaa tacactcagt ccaacagctg
     3061 aagggatttg ttctgagata gcaagatagt aagtaaaatc ttcagcgatt tctccagaaa
     3121 caatcggcgt ttgcccagaa aaaggttctt ttaatcctaa gtcttttgtg acagtaaaca
     3181 ttccttgtgt tccaactgct ccccgcacat cgattttacc ttcactattt agaggaagac
     3241 tgagatgcgg atttttgatg taacctttca catctccctt tccatttgca tctactacaa
     3301 ttcctgttgc tggaccatcg ccttggattc gaacagttag tttgtcttct cctttgagcg
     3361 tcgcaccaag tagcagacta ccgaccaatg tccgtcccaa agcagctgag gaggtgtgcc
     3421 aagtatcatg acgtctttgt gcctccgcta cggtatttgt tgcttgaacg gcgtatgctc
     3481 ggacgaatcc gtcgtgagca agtgccttaa ccaaataatc tttcatttgt tatgtactcc
     3541 tttttccgtt tttaaactca tagtgaatca tactagcaac tactgctttt ttcaactttg
     3601 gaatgcttct tttaaaaata attcagaatc atctagaaaa caggacatca ccctatttac
     3661 aacttaaata aagaaatctc ccgaaaaccg gtttttgttc cggttttcgg gagtcatatc
     3721 agatcaattg acctatattt ttttatttgt attgatcgtc tgaatgatta tcttctgatt
     3781 gttgagaatc tgaatcatgt tctgctttat tttcctcatt cagttcatgt tttgcttctt
     3841 caaaatcacg tttttcttcc gcttgttttt cagcgtcttt ttcttccaaa gcacgttttg
     3901 cttcttcaaa agttttcgct tctttttcgc ttggataatc atttgactca gtaccttcag
     3961 gcatcacacc gtgttcaaac aatgacttga ttgctttggc atccaatgtt tcgaattcca
     4021 aaagtttttc agcaatcagt ttatgctgtg cacgatgagc ttcgatgatt tctcgagctt
     4081 tatcatgagc ttccatcaag atttttcgta cttcttgatc aatctcgaaa gcgacttgtt
     4141 ccgagtaagc ttttgtttga ccatagtcgc ggccaacaaa cacttgatgg tttccttcat
     4201 attgaacagg acctaaacga tcactcattc catattctgt taccatgctt cgtgctagag
     4261 ctgtcgcttg ctcaaagtca ttggaagcac cagttgattg gacattgaag atgatttctt
     4321 cagctgtacg tccaccaagt aagcctacga tttgttcaaa catatcttct ttcgtcatca
     4381 agaactgatc ttcttttggt aaagcgatca tatatccgcc ggcgcgtccg cgagggatga
     4441 tcgttacttt gtggacgacc cgagcgcgac tcaatactaa tccgacaatc gtatgaccag
     4501 cttcgtgata agcaaccatt tcgcgttctt ttttgctgat tacgcgatct tttttagctg
     4561 gacctgcaat cacgcgatct tccgcttcat cgatatcaga agcatcgatt ttctttttat
     4621 ttcttctagc agctactaac gctgcttcat tcaagacatt ttctaaatct gctccggcaa
     4681 aacctggtgt ctgttgagcc acaactttca agtcaacgtc atctgccatc ggtttattcc
     4741 gtgcatggac tcgcaagatt gcttcacgac cttttacatc tggacgtcca actaaaatct
     4801 ggcggtcaaa acggcctgga cgtagtaacg ctgggtctag tacatcagaa cggttggttg
     4861 cagcaatgac gattactcct tcatttccgt cgaagccatc catttctaca agcaattggt
     4921 tcaatgtttg ttcgcgttca tcatgtccgc cgcccatacc ggcaccacgt tgacgaccta
     4981 ccgcatcaat ttcatcaatg aaaatgatag ctggtgcgtt tttcttcgct gtttcaaaca
     5041 aatcacgaac acgacttgct ccaacaccga caaacatttc tacgaaatca gaacccgaga
     5101 tcgagtaaaa cggtactcca gcttctccgg caacagcttt tgctaataag gttttacctg
     5161 ttcctggagg tccttctaaa agtacacctg ccgggatacg ggcacctaat tcaacaaatc
     5221 ggcgaggatc tttcagaaat tcaacaactt caactagttc ttgtttttct tcttccgcac
     5281 ccgctacatc agaaaaacgt acgcgattag cttttttgtc tgcttctttg gcttttgatt
     5341 taccaaagtt catgacacgg ccgccaccgc caccgccgcc gccttgttgt cccatcatca
     5401 tgtaaaagaa aaagatgatg attacgattg gcaagaagct aagcaatagg gaaacccata
     5461 taccgctgct tgattcttct tttactgttg tagcaacttt gttttctttt gccagttctg
     5521 ttacttggct caatgttgta tcatttggca aaatgattgt tgtgaaatgg gtagtagtcg
     5581 tatctgttga acctaagata gctaacccac cgctgttagc gacggtctgc tgttctttgt
     5641 attcaccagt gatcttatat acaccatttg caggctgcac ttcaaattct ttgatcttgc
     5701 ctgcttgtag ttgttctgtg aattttgagt actcgatatc tgacgatcgc tggccgttat
     5761 taccaaaaat gaaataaacg accattacca tcgctaagat tacgaggaca taatacaagg
     5821 catttttcat catgccgttg ttctttttgt tcatagttgc cctccctaag cgtcaattta
     5881 atttaacagt tttttatcaa tcctgaccat tctattgtac cataatttaa ttgagataca
     5941 gcattaattt gattgataaa cactaggttt caatacaccg atgtacggaa ggttacgata
     6001 tgcttctgca taatccaagc cataaccgac cacaaattca tttggtacgt tgaagccaac
     6061 ataatctgct tcgatattta ctactcttcc ttcaggtttg tcaagtagtg taacaatttt
     6121 gactgatttt gctttgcggt atttgaaaag atccactaaa taagcaagtg ttcttccgct
     6181 gtcaatgata tcttcaacga tcaacagatc gcgaccttct acattcgtat ctaagtcttt
     6241 gacgattttt acttcccctg acgagactgt tgcattcccg tagcttgaaa catccatgaa
     6301 atccaattcc aaatacgtat cgatagaacg aacgatatct gccatgaatg gtaccgctcc
     6361 ttttaagaca cctactacta ggggattggt gttttggtaa atttctgtta actctttgcc
     6421 tagttctttg caacgaactt gtatctcttc ttgtgagatc aaaattctct caatatcctt
     6481 ttccaacatc aggttctcct tccaattgct tctttttgat atttgtaaag aagtatgtag
     6541 tgtattttat cagtttcttc acgaatactc aaatatgaaa aggcaaaagg tatcaagcta
     6601 tatatatttc ttttggcatc tgtaatgatc caagcatgct gcctttgtga attaggtact
     6661 ttctgatcga taaaatatct agatactttt tttgtgagat tctctgttaa tttaatgcgg
     6721 tctcctgctt ttcttttttc gacatacagt tgcacatcag caggaatcca aatgtcatga
     6781 gaaaatagag accatgaatc tgttgctttg atgtcccctg cattttcagg tttgaccaga
     6841 ccaatccatt ctgtttcatt caaatatatt ccttgttctg gaatcagcaa caagcgctgg
     6901 tcttctgtct ggctagttgc ttgtttttct tttttagaga gtacaacaaa atgatactct
     6961 cttttcagta tccaattatt gccaatactg agttgccatt ggcttttttt ctgttgccac
     7021 tggtctaaaa tcgactccat ttgttgttct ttcaaaataa ttcctgtttt tgagaatgct
     7081 ttgtcgaaaa aggagtaaaa aaaatagtat cgttcagcat ctgtcatttc ttcaatcatt
     7141 tctgcagaaa atcgaaattg ttcctcccac tgttcgactt ccttttcgat caactgtccc
     7201 atatattttt gaatgacttg gtctgcccat tggatctgtt gcgaaaattg ctggaaatgt
     7261 ctcaacgcct gtgtattttc ttgtttcaat tgaggaacta ccaaatgacg aagccgattt
     7321 ctctggatat ctaacaattg gtttgtctga tcctcaaagt aaacaagctg cgattccgct
     7381 gcataagtat ataggtcttc tttgctaaaa ctcagcaacg gacgaatcag tctgcccgta
     7441 gcaaatggtt gtacttcttt gattccagaa aaagtattta actgtccccc acgaacgatt
     7501 ttcattaaca ccgtctcgat ttgatcatct ccgtgatgag cagtcatcaa cgtgtcatat
     7561 tgtccttctt ccatcacgcg agtgaattct tgataacgaa agttacgagc ttctgtttct
     7621 atggcggatt tggctggatc ttcccaaata cttacatata aagggagatt cttctcttca
     7681 caatatgagc gaagataggc agcttcttct gctgattctt ctcttaattg gtgattgatg
     7741 tggacgatac ctaaagaaaa accgatttgg cgttgcactt gtaaaagtaa atggagcaaa
     7801 accatcgaat caacaccacc tgataccgct gctaaaattc tcgatccttg ttgccagaat
     7861 ccttgttcat tcccgtgccg aataaatgac tgctgtaata gcggtgcttt tttcccgcct
     7921 ttttcaacgt tcatcctttc cacacccttt cttcctaaaa aaaagagagc gggaaaacgt
     7981 ctaaaacgac aattaacctg ccctctgttg atactatgac ccaaatagtc gcactatcat
     8041 tatttgcggc tttttagctg cgacgtccgc cacggccacc gcgctttcct tctgtgtttc
     8101 gcttcaatga agataagcgg tcatcgctat ctttcaaaaa tgaactcatc aatgaatcga
     8161 agtcttcttt ttgagctgaa ggttgactgc gagaaaaaga ttttttctgt gctggacgat
     8221 ttcggttgtc acggggatct ttttgttgat attttttagg acggctttct tctccagatt
     8281 cagcaggttg ttcctgcgct ttccggatag atagtccgat ttttccatca tcatttactg
     8341 aaataacttt aactgttact tcatctccta cacttaaaac atcatggatg tcttttacat
     8401 agccatttga cacttcgcta atatgaacta gacccgtttt tccagcacct agatcaataa
     8461 acgcaccaaa atttgtgatt cctgatactt ttccttgcag ttttgctcct acctcgattg
     8521 acataaaaaa aatgttcctc ctaattattt ccctttttta tattcctgct tattttgcag
     8581 ttgtagaact agttgattga tctgtttcat ttgtcgagct gtctgtattt gattctaata
     8641 taggataaac tttttcaccg tcttttgagt aaaagaattt gcttctggca agtttagcta
     8701 catactcatc atctttcagc aatgaaacat cttggtgcag ctgatcaacg tctgcgttga
     8761 cttctttcat ttcagtattt gcttcgactc tcaattcgtt caattgatgc atcctttgca
     8821 tgtcatggaa aatctgcaca cctattatcg cgaaaatgac caaagcacca acaaaaattg
     8881 cagccagtct gcgtcttcga aaaatcagtt gacgttgttg ttgctgaaat tcagcatact
     8941 ttttctttgc atattccgta tctagcgcag cgattttatt gctttttttc gtcacttgga
     9001 ttcgctccaa tctttttgat tgtctttttc attataccaa tatcgtgaaa gcttgtctaa
     9061 tctatttctc tagtgtttct gtgcgatttt cagaaataat ttcgtacatt ttttgtgcat
     9121 cttctttttt ggttgattca tgtaattccg taattttcac ttccaacgtt ttgttgccaa
     9181 actggacttt caaaatatcg cctactttga catcactgga agatttcgcc aatttaccgt
     9241 tgatttgaat tcttccttta tcagctactt cttttgctac tgatcgtctt ttgatgattc
     9301 gggaaatttt taaaaattta tctaatcgca tatcttattc ctcacttttt aattttttta
     9361 tttaatcgca ggattttctt accaaaaggc aacattagcc attctcgtac tgtaaacaga
     9421 cgaagacgaa tcactgcata aatgaacaca gaagccccga tcccaactcc tatcacgctg
     9481 acaaaaaaag cagtggaacg atgagttaca ggaccaaata ctatattcaa tacaccataa
     9541 tacagcagca gtactactgt catacaaaga aggctgaaca tcaacttccg tccaaaatgc
     9601 cgttctttcc aaaaagcatt tagctctttt gtttcaattc gaacaaaata ccaaagcgtc
     9661 acacctaatc ctaaaagggt agacaggctt gcacctgctg ttcctaataa accggtcaga
     9721 aaagaagtag tcaatccttt taccaatagt ccccatcctg cgccttttaa agaagggcga
     9781 aacgagttct tgctttgagc aatactttga taagcttgga tgactgcagt gaaagcaatg
     9841 gaaaaaacaa ataatacaag cgctgcattt cccgcataat ctttaaacaa cgcataattg
     9901 atataaggga gcagcaaggc taatcccaaa gacgcagcta atgctaaagc ggtcgtcaat
     9961 ctaagataga ttttggctgt ctgtaaaaac tgacgataga tccggttggt caaatgacga
    10021 gtcaacgcag gcaggaatgt cgcacttaat gcagtggcaa tcactaaacc taattgtact
    10081 aaaggctgac ctcgatcata gacccctttt gctatcttcg caccgtattc tgacagtccg
    10141 taaacttcca aagcattttt tacaaagaaa gagtcgatca gctggaaaaa gataagcaat
    10201 ccactataaa tcgaaaccag tccgccttct accagaaaac gccggatcaa gggctttgac
    10261 ggctgtttga acaatggaaa ccgtcggaag cttaacgctc ctccatgaat cttttgttca
    10321 tagtagtgaa ggatcccata tgcgcataaa ccgccaaaaa cagctccact cattgctgcc
    10381 gtccctgttt ggtacaccgt ccatccaagc tttctaaaag caaacgcact acagacaatc
    10441 acaaaaacac gaacgaactg ctcaactact tgagaaacag cagttggttc catcaagaat
    10501 cttccttgga aattccctcg ataaaaagat agaccaggca tcagcaaaaa ggtaaaggaa
    10561 actacttgga tcagcggttt caattgtatg tctcccatca tccaagcaat ccagctgcta
    10621 aatgcaaaga caaacaacca caaaaagaca cctgtccaaa atactaaggg ataaagattt
    10681 tgcaaagctt gctttcgctc gaaaggattc tttctttctg caacgtactt tgatatgaac
    10741 tgcggaagac cggataaagc taaagtcatt gctatcccat aaattggata aacttgctga
    10801 taaacataaa aaccttcgtc gccgactaag ttttggaggg gaattcggta aagggcactt
    10861 aatacttttg ctatgaaaga agcaatcgtc aatacaaatg ctccttgcat gacgcgccgc
    10921 atttctttat gatccaaatc attgctcctt cctacgctga cagatatttt tgctcacgca
    10981 acgctttgac aaacttttgg atttcctgaa gccatactgc ttcttccatt tggttgggga
    11041 tcgtcaagcg tatcaccatc tgttcttttt caacgcctag actggctttt agttttgtcg
    11101 ctgtcagtgc ttcgaataac tgttccacac tatagcgttt tgttccaact ttacttagag
    11161 taaagactat atgcgcctcc tgtttcctta tcgtttctag gagcgctcga tcgccatcca
    11221 ttttgatctg cccaattgtc aagagatgtg ctacttcttc tggatattct ccaaaacggt
    11281 cgagcagatc atcttctagt tcatctagca tttcttgcga atcaagttca cgaattcgtt
    11341 tatagatctc gattttctgc cgttgatctg ccacgtatgt ttcaggtaga tacgcatcga
    11401 caccgaggtc gatctcaaca gtggtcttct ccacttgact attctttcct tgtttacgag
    11461 aaacagcttc gcttagcatt tgagaataca tatcgaaacc gactgcatca ataaatccat
    11521 gctgctgagc acctaagaga ttacctgcac cgcgaatgga aagatcccgc atcgcaatct
    11581 tgaatccaga tcccagttct gtaaaatctt tgattgcctg aagacgtttt tcactgactt
    11641 cgttaaggat cttctgctgc tcatacataa agtaagcata tgcgacacgg ctgcttcttc
    11701 ctacccgccc tcgcaattgg tataacgtgg ataatcccat ataatcagcg ttctcaacga
    11761 acaacgtatt tgcgttcggg atatctactc ctgtttcaat gatggttgta gtgacaagaa
    11821 catcatattg accttcaata aattcaaaaa gcgtattttc taattgcgcc tctgtcattt
    11881 gcccatgagc ataaccgatc cgtgcttccg gaacgagttc ttggatttct tctacttttt
    11941 gttcgatcgt ttctacccga ttatataaat agaatacttg tccacctcgt cccatttctc
    12001 gatggattgc ttcgcgaata gccccaggat ttttttccat aacatacgtt tggatcggat
    12061 aacgattcgc aggcggtgtt tcgattactg aaagatcccg cacgcctaac atcgacatat
    12121 gcaaagttct cggaatcggt gttgcagtca gagtcaaaac atccacttgt gcacgtaact
    12181 gtttcaatcg ttccttatgt tttacaccaa aacgttgttc ttcgtcaatg atcagtagac
    12241 ccaaatcgct aaattcaata tcttttgaca aaattcggtg ggttcctaca acaatatcaa
    12301 cttgacctgt acgcagttgt tcgatggttt ctttttgttg ctttcttgtt ctgaaacgac
    12361 ttaatagccc gatatttacg gggaaacctt caaatctttc cagcatcgtt tcatagtgct
    12421 gctgtgccaa gatcgttgtt ggaactaaaa aggctacttg tttgctttcc tttatcgctt
    12481 taaaggccgc tcgaagcgct acttctgttt tcccataacc aacatcacct acgagtagtc
    12541 gatccattgg tttttctttt tccatatccc gtttgatctc cgctgcactt ctcaactggt
    12601 catcagtttc agagtagggg aaggcatttt cgaattcttt ttggtaggcg tcatcaggtc
    12661 caaaagcata tcctttttct gactctcttg cggcatataa tttgattaga tcgtcagcga
    12721 tatcctcgat ttttgaagag acttttcgct tggttttcgt ccattcactt ccgcctagct
    12781 tattgatgcg aggcgctttg gcttcagagg cgacatattt ttggatcaga ttcagttgag
    12841 taacaggaat aaacagtttg tcgtcgtttt gatacaaaat agtcatatag tcttggtgaa
    12901 cgccatctac ttctagcgtt tccatcccaa tgtatttccc gataccatga ttggcatgga
    12961 caacgtaatc tcctgctttt aactcattat agcttttcaa tcgctctgcg tttgttactg
    13021 tttgacgtct cgtttgtttt ttcgtcgttt tttggaaaat ttctttttct gtgatagcta
    13081 ctattttttc ttgaggaagt tcaaaaccag cctgcaaagc tccttcaact aattgtacct
    13141 gtcctctgat caatgcattt ttttctgttt ctactactaa tatgtcttca tctcgaagca
    13201 tttgttctgc tttgcgtatt ctgtcctttg tcggaataaa gatcacaaca gtctgttttt
    13261 gcttgcgcca acggtccatt tctgttttca gcaatggcat ttgtccgaag aactgttgca
    13321 tcgtccgata ttgaaaatta tggattgctt ggaaacgaag atttcccatc cctttttgga
    13381 agagtgagaa aaaggttgtg gtgaactttt ccttctgcac gattttttgt atatctgctg
    13441 aaaatgtctg ctcagaaaac acccgcaatt cgctgatttt ttgagtctgc cattctgccg
    13501 cttccctttc gatttcccga tttgtttcca tgattcgctg ataatcatca acgactagta
    13561 aactatttga agggaaataa tccaagatcg tcacagattc ttggtaaaga agatctgagt
    13621 agaattttgc ttcttctgtc gggacacctg cttgccagct tgaagtcagc tgaccgaagt
    13681 aatcttgcaa aaactcgcgg tctgcttctt ctgtggtcgc agcaagccgt ttttctagca
    13741 ttttttgcat ttgctctatt ccatgttcta gatcctctgg tccgtagact tgttcactcg
    13801 ttggggaaac ccagatttct tccgtttttt cgattgagcg ttgtgtttct gcttcaaaat
    13861 accgcataga atctatctct acatcaaata gttctacacg aacaggatag gttgtcgtta
    13921 acgggtaaat atcgataatg cttcctcgaa tactgaattc tcccggtttt gcgaccatct
    13981 cttctcgtac atagcccatc aaagtcaatt ggcgaggaag attttccacg tctatctcat
    14041 caccaatatg ccaattcaat tgcgcctgta gccaagtttt cttattcggc agtcgtttgt
    14101 gcaaagatgc gactggcaac aaatagatac ctgctttttt ttcttgaagt gcgttaagcg
    14161 ttgcaactct ctcgcctcgc gcttctggag aagaaaaggc catttcagca gaaagcactt
    14221 catccactgg aaataaatgg atctgatctt gcggaatcac atgttgcaga tcttctgcta
    14281 actgattcgc ataatacaaa tttggcatca gaataatcat gtttttattt gttttcttaa
    14341 acgctcgagc aaatagaagt gttttcgctg agcccgctaa tcctgtgatt agttgtctag
    14401 gcattttttc ttctaaattg ctgacccatt cttttacttg cggatctttt ccgactaatt
    14461 gaataatatc cattcctttt cctccttcct caattgaatc gattcatcgc atccacgaac
    14521 gaatgccctt ctatgagata ttcgactgct ttaacagatt gacacatgct ttcttctatc
    14581 aaaggctgat tttctttgct gaaaggacta agcacatgct ggactactgt ttttttccct
    14641 tctggcctgc cgattcccac cttgattcga tcaaagacat tcgtattcaa atgggaaata
    14701 atacttttga taccgttatg cccgccggca cttccctttt gacggagccg gatttttccc
    14761 actgccagat ccaaatcatc gtagattacg actaattcct ctggataaat cccaaaataa
    14821 gtcattagtg ggccgactgc acgaccagat tcattcatga atgtttgtgg tttgactaaa
    14881 aggatctttt ctccattatg aaaaaattcg gcaacttctg cttcgaacgg attttttttg
    14941 aaagtagctt gatgctcgcg tgcaatttta tccacgacca taaagccgat attgtgtttt
    15001 gtatattggt atttggtacc tgggtttcct aacccgacga tcattttcat ttttgttttc
    15061 cacctaattc taaaaagcag cacaaaaggc tggactgcta attagcggtc cagtccatcg
    15121 agcttttttc ttttttatac ttgtcaatgc atagtataac acaaaacaag gcgtttcggc
    15181 taaaagagaa tcgttaataa atgataaaga aattaaaaat ttcttcaaag tttaatgaaa
    15241 taattgatat ataaaaatag tgaaataacg cacatgtaag cttttacata taatacaacc
    15301 ttgttatctg ttatatttta tagccaaata gcgtgacatg gggcttgaga aatgttagca
    15361 taagcatggg aaaaaacaaa tcaatggaag gattgatact aaatgactgc agctgcagaa
    15421 aaaaaagatc atcaaaaagt tattcttgtt ggagacggcg ccgtaggttc tagctatgcc
    15481 tttgctctag ttactcaaaa tatcgctcaa gaagtaggta ttgtggatat caatactgct
    15541 aaaactgaag gagacgcaat tgacttgtct cacgctttgg catttacttc acctaaaaaa
    15601 atctattctg ctacttacgc agacgcacat gatgctgact tagttgttat tacagctggc
    15661 gcaccacaaa aaccaggtga aactcgttta gacttagtaa acaaaaacct aaaaatcaac
    15721 cgcgatgttg tcacacaaat cgttgaatca ggatttaacg gtatcttttt agttgccgct
    15781 aacccagtag atattttgac ttactcaact tggaaattct caggtttccc taaagaacgc
    15841 gtaatcggtt caggtacctc tcttgactca gctcgtttcc gtcaagcact tgcggaatta
    15901 gttgacgttg atgcacgtaa cgtccatgct tacatcttag gtgaacacgg agattcagaa
    15961 ttcccagttt ggtcacatgc aaatgttgcc ggcttgcaaa tctatgaatg ggtaaaaaac
    16021 aacccagaaa tcgatgaaga agctatggtt aacctattct ttggcgtacg tgacgctgct
    16081 tacacaatta tcgagaaaaa aggcgctact ttctatggta tcgcagtagc attagcacgt
    16141 atcactcgtg ccatcttaga tgatgaaaat gctgttcttc ctttatcagt attcatgaat
    16201 ggcgaatatg gattgaacga catctacatt ggtgcacctg ctgttatcaa ccgtcaaggt
    16261 atccaaaaag taatcgaaat tcctttaagt gacagcgagc aagaccgtat ggctgcttct
    16321 gctaagcaat taaaagaaat tctagatgaa gcttttgcta aactagacgc tgaataatct
    16381 ttgaacatga cggaaaacat ctattcggtg ttttccgttt ttttatttta tcacccttat
    16441 ggtttctaaa ttttttcata aagtagagat aaccttcgtc ttttcctcta aattatgcta
    16501 tcatgagacc gttccaccct aaacttttac ttaaggagtt gtcgatatga caagatcttc
    16561 gcatcgaaaa aaatcgaaac atgttgcttt gctttcagtt cttggtgttc tcttagtgct
    16621 gatcagcttt tatacctatc gcagtacata ctacacaaag cattttttgc cgaatacaga
    16681 aataaatgga ataaatgtca gcaatctaac agtcgaaaaa gcaaatgaaa aattaaaaga
    16741 agcttattct gataaaaaac tggctattaa agaagatgga aaagtctggc aggaagtacc
    16801 aaaatccgag ctcggctaca aagatgattt cacttcggag ctttctccga tcctaaatga
    16861 acaaaacgga tggacttggg gaatgactta tgtctcagcg gcagaaaaac aagaaataga
    16921 tcctgtcagt caaaaccacc aaaaactaga cactaccgtt cagacattga caactaagct
    16981 gactgatttg aacaaagacc ggacacctac tactgatgca acgatcgaaa aagcaggtga
    17041 ctctttcgtt atcaagcctg aagtcaatgg aaatacgatc gacgtcgatg ctgcggtcaa
    17101 acaattaaaa agtgcggtaa actctggtaa agatacaatt gaattgactg aattcaaaga
    17161 aaaaccaaaa gtaacatctg aagacagctc actgaaagaa caactcgcat ccatgaatgc
    17221 tatcgcaaat gtaaaagcta cttacagtat aaacggtgag actttccaga tcccatcaag
    17281 tgatattatg agttggctga cctacaatga tggaaaagtc gatttagata cagaacaagt
    17341 acgtcaatat gtaacagatt taggcacaaa gtataacaca agtacgaatg acacaaaatt
    17401 taaaagtaca aaaagaggag aagttacggt cccagttggc acttacagtt ggacgatcca
    17461 aacagacagt gagacagaag cattgaaaaa agcgattctg gcaggccaag attttactcg
    17521 ttcacccatt gtgcaaggtg gcacaaccgc tgatcatcca ttgatcgaag atacgtatat
    17581 cgaagttgat ctggagaacc agcatatgtg gtattacaaa gacggaaaag tggcccttga
    17641 aacagatatc gtttccggaa agccaactac acctacacct gctggagtct tctatgtttg
    17701 gaataaagaa gaagatgcaa ctttaaaagg aacaaatgac gatggaacac cttacgagag
    17761 tccggtaaac tactggatgc cgattgactg gacaggtgtt ggtatccacg attcagactg
    17821 gcaacctgaa tacggtggag acttatggaa aacccgcggt tcacacggct gcatcaacac
    17881 cccaccaagt gtaatgaagg aattattcgg gatggtcgaa aaaggaacgc ctgtattggt
    17941 cttctaacaa aaataatata taaaaagaaa gcacccgtac gattggtaca ggtgctttct
    18001 ttttattatc taacaatgtg ctacttacat ttcagcagca gtaaagactt ctgaaacatc
    18061 atcatcgtct tctagcttat ctactagacg ttccaattgc tctttttgtt cctcatttaa
    18121 atcaatcgtc gtttgtggaa tcatcgtcaa ttctgcttgc gccaaagtga actctttttc
    18181 caactcatct cgtacagcag caaaatcttc tggtgcagta taaatctcga atacttcagg
    18241 agaagtttgc agatcttctg cccccgcctc taatacatcc tcaaacatcg tctcttcatc
    18301 aacagtcaac ccatcgcgtt caatagcgat atatcctttg cggtcaaaca agtaactgac
    18361 tgaacccgtt tctcccagtg atccaccgtt tcgagtaaaa gctactcgga catttgtcgc
    18421 tgtccgatta cggttatctg tcaatgcatg gactaagatt cctactccac ccggaccata
    18481 tccttcatac gtgatttcat cgtaattcgt ttcatctacg gcactcgtag cctttttaat
    18541 cgcccgttcc acattgtcgt taggcatatt tgcagctttt gctttgtcca caacaagccg
    18601 caaagctgga ttcatagatg gatcaggacc gcctgcttta gctgccatat aaatttcacg
    18661 agaaagtttc tgaaagactt tccctcgttt tgcatcttgg gcattttttc ttccttggat
    18721 attatgccat ttactatgtc ctgacatgat ttttcctccc ttgttctttt gagaatacac
    18781 ttctattcta gtactatttc acaaaaaaac aaagccacag ccaatctata aacgcttctt
    18841 gaatgccgca aaaagcacac ataatatcac agcagtcaga gcaccgatcg aatccaacat
    18901 gacatcttgg aacataggtg ttcgtccacc ggtcatcatc tgatggaatt cgtccaaacc
    18961 tgcgtaccct gttgctgaaa gccaagcaag gatcgctgtc agccaccaaa tttttagctt
    19021 ggggaaaaca cctaaaaaca agctgcctcc caaaataaaa taggtaccga aatgtgcgcc
    19081 cttccttaaa aagaactcta aaaatttggc gtagcccaga tggtcgatac tcaccatact
    19141 tccaccataa ttaaaacgta tacccgctaa tgtgtcttta aatggctgat taggcagcca
    19201 gctttctaat cgcgaaactt gtgattgctg tccgtaagtt tgagaagaac tgtaaaataa
    19261 gattataacg actatcagtg cgattactaa ataaatattt ccgtttttca tttgtttttt
    19321 tgaagaattc ataagtcacc tctgtatttt atcttagact ttttttgaag aaacaacaat
    19381 cattttcata gagacttctt ccataaaaaa gtgctatact taattttgta ttacaatatg
    19441 aagggagttt tttcatgagt tattcattaa attggaatct agattctatt ttttccggag
    19501 gcagtcattc tgatgctttg aaccaacgga tgaagcaatt ggaagaccaa atgaacgagt
    19561 attatcaccg cgtaacaaaa tggtcaccta gttctgacaa tgcagagcag ttaaacgcta
    19621 ttcttcaatt gcaagaaacg attacgaatg gttttaccca atgcagcagc tatattactg
    19681 cattgctttc tgccaatgtc aatgattcag atgcaaaggt cttatcaggc aagctttacg
    19741 caatgctgcc tcgtctgcaa tcagccgaaa ctgtattgtc aaagaaattt gcagaaatat
    19801 ctgacaatga ttggaatcag atgctttctc aatcttcgtt tgaaacaatt gcttttcgtt
    19861 taaacgagat tcgtcgtgat ggctcacaat tattatcaga agctgaagaa aacattataa
    19921 atacgctttc tttagatggt ctaaatgctt ggagcagtca ttatgatacg attgtagcca
    19981 gcatttcgat tcccttcgaa caagatggac aagtagtcga attatctgct ggacaagcct
    20041 tcaataagat gatgggcgat ccagatccaa aagtcagaga aacacttttc gcagcatggg
    20101 aagaagcctg gaaagaaaag gcacccctct tcacggatac tttgaatcat ttagatggtt
    20161 ttagactttc tgactatgaa cttcatggtg tcacagattt tctacaaaaa ccattagagt
    20221 acaatcggtt gaagaaagaa acattgtctg tcatgtggga tacaatccag aaaaacaaac
    20281 aaccccttgt taattacttg actagaaaag ctaatctttt cggtaaagaa aaaatggaat
    20341 ggcaagatca agatgcacct attattttag gcgatttgaa agaaaaaacc tttagttttg
    20401 acgaagcagc agcatttatt atcgaaaact ttaacaaatt cagtccaaaa atggctaaat
    20461 ttgcccaatc tgcttttgaa aagagctgga tcgaagcaga agatcgtcct gggaaacgtc
    20521 ctggtggtta ttgtactgag ttaccagaaa caaaagaatc aaggatcttt atgacctaca
    20581 gtaattctgt taatgaggtt gcgacacttg ctcatgaact aggacatgct ttccatagca
    20641 gcacgatgtg ggatttacct tctttaaatc gcgaatatgc catgaatgtc gcagaaacag
    20701 caagtacatt cgcagaactg atcgtagccg atgctacatt aaaagtcgca aaaacaaaag
    20761 aagaaaaaat caatttgcta gatacaaaac tgcaaaatgc tttagctatg ttcatgaata
    20821 tccattcccg attcattttt gaaaatcgat tctatgaagc acggcaagaa ggattagtct
    20881 cagaagataa gatcacagag atgatggttg aggcgcaaaa agaaggctat caaggagctt
    20941 tagctactta ccatccatat ttctgggctg caaaattgca tttctttatt gatgacgtac
    21001 cgttttataa cttcccatac acatttggct acctctttag tttgggcatc tatgcttacg
    21061 ccaaccaaaa gggagcaaat tttgaagaag aatatatcca tttactacgc gatactgcct
    21121 caatgacgac ggaagatctt gcgaagaaac atttgaatgt cgatcttacc caaccagatt
    21181 tttggcaagc aggtatcgac atggtgactg aagatatcca aacgttcatg gaattgacag
    21241 aagaatttat ctgatttcta ttttatcaca ataaaaaaag agttagtcca gaatgggcta
    21301 actctttttg attaatcatt cttacatgct gacagcaaag tcaggggcaa accattgaac
    21361 tgaaccaact tttacgcttt cgcctggttg aggagcatgg atatattgtc ctccgcctaa
    21421 agcaatcgct acgtggtaag ttccgccttg tgacccccag aataacaagt ctccagcttt
    21481 tgcttgagaa actgaaattt ttgttccagc tgattcttga ggaactgtcc aaccaccgat
    21541 gtcacgacca gttacttgca tgtaaacata gcgtgtgaac cctgagcagt caaagccact
    21601 tggatcttta ccgccccaaa catatggagt accaatatat ttgtaagctt ctgctacgat
    21661 tgctgcacca ttcacacttc cagaaggagc tggagcaggt gttacaggtt ttggttgttc
    21721 aggtgttggt gttggcgttg gagccggagt actacttcct gtgccgtttc ctgtatcaac
    21781 actttgatct gttgatggtg ttgtaggcgc aggtgttgtt gattcttctg ttgttgaaga
    21841 ttcaggcact gttgttgatt cttctgttgc tgaagattca ggcactgttg ttgattcttc
    21901 tgttgctgaa gattcaggcg ctgttgttga ttcttctgtt gctgaagatt caggcgctgt
    21961 tgattcttct gttgaagatt caggtgttgt tgattcttct gttgctgaag attgtgtagc
    22021 tgatgatgat tcttcagtca ttgaagattg tgtagctgat gattcttctg ttgctgagct
    22081 ttgtgcagta gatgaagctt gagtagcttg tgcttcagcc tctgcttgtt cgcgtgcttc
    22141 tttttcagct ttttcttgtg cagcttgttg acgagcttgt tctgctagac gttgttgttc
    22201 acgaatacga gcttgctctg cttcagcttc tgctttttga cggttcaagt cagctttctt
    22261 gtcttcagca gttgcttgtt cagcagctaa tgaagttttc agtacgttca aatcagcttg
    22321 tttagataaa agatcgcctt tttgagattc caaagcagct tggttttcag ctaattcttt
    22381 tagtttagca tcgttttcag cttttttgtc ttctacagct tttttatctt gtttttgttg
    22441 ttccatcaag tcgttgtttg cttttaccat cgttgtcatt gcttgaacgc gtccaatagc
    22501 atctgctaat gaatcagcat tcaatacagc atcgatgtag tttgagcttg tgttgcttac
    22561 ttgtgcttcg cgtgcttgtt tttggattgt atcttcacgt ttttcaatac gttcttgtaa
    22621 atctgcaatg tcttttacta attgtgcaga ttcttgacgc aatgtatctt gttttgctaa
    22681 taggtcttgt gcttgtgtgt tgatttcaga aacttggctt tctaaggcat cgatttgtga
    22741 ttgtgcatct gcttgttgat ttttcaagtc tgcaatcttt tgatcttgct gttgtatctg
    22801 agaatcaaaa tcgtccgccg cggcagcgat cggtgatgct acggcagtca aggtcattga
    22861 acataccatt actgctgata ttaaactctt tttcactctt cattcctccg actggcttaa
    22921 tttaataaat atctaaatat atttaagtct ttcttaacga tataaaaatt gtaccatagc
    22981 agtgtgtcaa cgatataata gttatgttac aaaaatgttt caaaacaact tttaaaaatg
    23041 acaaaactgt tcgtttcaga aaatgatcat gaaaaagccg cgttaagtct agcatttctt
    23101 aagataacaa cgattctttt tcgctttcga cctaaaaata aaaaaagaaa ttattcatca
    23161 ctgaataatt tcttaaaggg aaaaatgaat aatacaaata taatcatgtt caacagcagt
    23221 gtaggtccta aaaaccttgt aataaaatac gtgttattta ctactgctaa tttaaaaatc
    23281 aactggacca ccatcgtaaa caattcataa cccgtgacaa agatgatcat actgaaaaat
    23341 tcagtaaaga tgttgacatg gataacgtct ttcattacat acatcaacca tacaattaaa
    23401 gggagagcta ctgcatagat accgataacg ccaatatagt aagcgtcata gatagccccg
    23461 agaacaatcg tggtaatcag taaataacgt ttttcaaacg ccatactgca acataataat
    23521 gccaatatca gaaagtgggc atttgacata taggtgcctt tcgaccactc ccctagcatt
    23581 cttgttaaat gaccatctat caacatcaaa aagaacaaaa cgattggcag atagtacttc
    23641 attgtttctt tcttcaacat ggactaatcc tccgctagcc gttggacaat cgtcacaact
    23701 gacacgtcat acatttctgc ataaggtttc acataaactt cccgatccag cccataacta
    23761 tctggtttcg ttttaataac cgtaccgatc ggcaagttag ctggagaatt ccctccaaga
    23821 ccggatgtct ggacaacatc cccttctttg atatccgtat caccagttaa ttgggtcacc
    23881 actaaggcat ggagcttttc atcatagttt ttaagcaaac caaacgcttc gccattagcc
    23941 gaagataccc gtactggaaa atgattggag ctttcattag aggatgacag taattcgatt
    24001 ttagacgaag ccgtattgac ctcgatcact cggccaatca atcctttttg cgacatgact
    24061 gccatatttg cttcgatacc gtctttagaa cccttgtcta cgatcagcat gtcctgccaa
    24121 ctgtcaggcg aacgagtaat gacatttgcc gttacttttt cgtaactagt cagcgtctga
    24181 ttcaactcaa gttctttttt caacgcttcg atttctctct cgtaattctt gttttgctgt
    24241 gaaacgtcat catagctatc gattttttct tttagccgct cattttcggc ataagttgaa
    24301 aaaagattat ggacagaatc tactccattt cgtacccacc gtactggggc agagattgtt
    24361 ttatcaacca ttgcaacact gtcattaacg atggattgga agaaattggg ctttccttca
    24421 ttcgctcgct gcgcagcggt cacacttagt atcgtcacca cgatgataac aataaccaag
    24481 gtaataataa tatttttatt aggattgaac ttcttcacaa agacacctcg aattaattag
    24541 actcttgtgt tcaattttat cactaaatgc cgtgaaacaa aaggtaagtt gctcctctta
    24601 agcttttttt tagcaaataa tagattctgt catttttagc ctgaaagaca aattttttta
    24661 tttgtttatg gatcaatctt tgctttgaat aactgcaatc ataccatctg aaaaagaaaa
    24721 ttctgcggta tctgaaagaa attcgttact tgcataagat gtcggatatt ctacttcttt
    24781 attttccaat acatacttgc tgccttttaa tgtaagattc gagacgggag tcaagcagca
    24841 ataagctaaa tacttcatat ctggtatctg tcttactata tgctctccag gcaaataata
    24901 agacaaataa ttttgacaat ctctgataat aagctgatgg gcaaagggtt tgaagcgagg
    24961 ttccatacct aaccagagat tggctaaaag atgatccaat cttccgcccg tagctccaat
    25021 caaagtgact tccgcttgcg ggtaacgttc aaatgttttt aagataccta actgtgtatc
    25081 tgtatcgtct ttttctgcag gggaacgggt atactctttg gcttttgcaa atacttcctt
    25141 ctgctcttcg ttcgacaatg aatcaaaatc gcccactgcc agatctactg ggtagcctgc
    25201 ttgaagcagg tacagcgcac cacggtctat cccgacatag gcatcgtatt tggacagcag
    25261 agactgcggc cagttttgcg gattacctcc agcagctaat aaaattttca tttagtctaa
    25321 tgcctctttt aatcgttcga tttgtccgac tggattttcg gctccataga tatatgatcc
    25381 tgcaacgaag acatccgccc ctgcatcttt acagattttt gctgtttctg gaacgattcc
    25441 gccatctact tcgattgcat aagtccaatt gttctctcta cgtagatcag cgagttccgt
    25501 aattttttct actgtttctt caataaagct ttgtccgccg aacccaggat tgacagtcat
    25561 gactagtact tgatcagcca aaggcaaaac atgtttgatc atggagactg gtgttcctgg
    25621 attgataact actccagctt taactcctaa gctttttgtc atttgaagtg cccgatgaat
    25681 atgaggagtt gcttcgacgt ggacagtaat gatatctgct ccagcttttg caaatgctgg
    25741 aatgtagttt tctggatcaa cgatcatcag atggacgtct aacggtaatt tagtaacagg
    25801 acggattgcc tgaacaatat ttggccctaa tgtgatattt gggacaaatt ggccatccat
    25861 tacatctacg tggatgtaat ctgcgcctcc tttttccact aactcaatgt ctctttgtaa
    25921 attggcaaaa tctgcactca aaatggatgg tgctatcttc attcttgttt cctcctattt
    25981 tcgtttacct tctttttttg catacattgg ttttcttttt tcgatttctt gtaagaattg
    26041 caaataattg tcgtaacgtg tctgtgcgat accacctgtt tctactctat gttttacttc
    26101 gcagccaggt tctttagcat gcatgcactc tctaaatttg caatggacag aagcttctac
    26161 aaattcagga aattgtctcg gcagttctcc tgcttcaatt gtcaaaaagt caatcgagct
    26221 aaatcctggt gtatctgcta ctaacccgcc atagatagga atcagttcca catgacgtgt
    26281 tgtatgccgt cctcttccaa gtgcatcaga aatctctcct gttgctaaat tcagttccgg
    26341 tgatatttga ttcagtagcg tcgattttcc tgctccagac tgacccataa agaccgatag
    26401 ccgttctggg aagtaacgga tcagttctgt cgtatcaccc gtatgattgg gtacaatcac
    26461 cggatagcct attttagtat aggtttgctt gatctcttcg attttttctg ggtcgtctga
    26521 caagtcggtc tttgtcaaaa aaataatcgg ttcgatcgac tcgtattcca aggtaactag
    26581 aaagcggtca agtagattat aagaaaatgc aggctctacg atacttgtga caatgattcc
    26641 aagatcaaca tttgtgactg gtgggcgaac taattgattt tttctcggca agatttccag
    26701 aagatagccg tctgtttgat tttcactctc aaagatcacc tgatctccga caagcggcgt
    26761 gattttccga ttccggaaat ttcctcttcc tcttgtttga taggtctctc cgtttgcgta
    26821 tacatagtaa aaaccgctga ttgcttttct gatttgtcct ttgataagtg ccacctccgt
    26881 ttttgtttat tttaccatac gaagaggaaa gtaggtgtta ttccatgcaa acttctcaaa
    26941 gtatatggct tgaaaattga tcaaaagaga tagaaacaca aaaaagagaa tgcaacaaat
    27001 caatgtcgca ttcccttctg atatatttta ttcagcactt attttgaact ttctgaggtg
    27061 ctagctgatg aacttgtgga gctggaagat tcttcttttg aagagttgct tgtgctactg
    27121 gagctacttg agctgctaga actgtctgaa gagtcttttt cagaactaga agacgctgga
    27181 tctggtcctt tagagtaaat tacgttcaca accattcctt tggtaattgt cgttcctgcc
    27241 cctggtactg tacgaatcac tttatcttta tccaccgtgt ttgaatattc ggaagtctca
    27301 tgcccgatat attctgcacc gacactagct aaataacttt gtgcttcgct ttttgtatag
    27361 ccggagatat cattcaattt aggctctgtt ccttggctta cgacaaaatt gatgtaagtt
    27421 tcttctgcta caacttcacc cgaggctgga tcctgactga tgatcgaacc tgatggtaca
    27481 gtgtcgctat agtcataagt agcactaata ttattgatat tgaatccttg tgtaacaagc
    27541 caattacgaa cagtttcgta gttttctcct acatgactac tcaaagtcac tgtttctggt
    27601 cctttgctga ctgtgaaagt aatcgtgtct gttttaggat cgacttctgt atcttctgat
    27661 ggagattgcg aaatgatcat tccgctttct acctctgaac tgaattcctc ttctttttga
    27721 atcaagtcag cagaaaaccc taattctttc aaacttgctt cggcatcttc ataactttta
    27781 ccactgtaat catctaattt gatttttttc gtgccgctac taatatacag agtgacttcg
    27841 cgtttttgct tgactgtcgt tcccgctgcc gggtctgtct tcactacatt accttcttcg
    27901 attttgtcat ctgcaatttc ttctgttttt gttgctactt ctaatttcgc ttttgcgagt
    27961 gtttctctag cagaagcttc agaaagatca gaaacatcag gaacaacaac ttctcctcgc
    28021 ccgccagaag caaagaatac agctgttccg attcctaaaa cagcaagaat agctaatagg
    28081 atcagccacc attttttctg tcctttcttt ttaggatcag gcagaacttc ttcctcctct
    28141 ggcaaggttt cgttttctgg cttgtctttt ggcagaggca tagatttgaa tgaatcaggc
    28201 attggtgcat cttccgtaag gggtgtgata acttttgttt cattatccat cacatgaggc
    28261 tgccattttt cttcgtttgc acgagctggt gataatactg tagaaagatc atcagacatt
    28321 tcctcggctg acttataacg gtctgcaggt tctttagccg ttgcccgtaa aatcacgttt
    28381 tccagtgctt gtggcacatt tggatcaagt gcttttatag atggaagatc atcttgaaaa
    28441 tgttttaaag caattgttac agcagattca ccatcaaacg gtacgctacc cgtcaacatc
    28501 tcataaagga tgatccctaa agcataaata tctgactgct tcgttgccat acttcctctg
    28561 gcctgctcag gggacagata atgaacagat cccagcatcg tattcgtctg cgtgatcgat
    28621 gtttcagata aagcgatagc aatcccgaaa tccgtgattt ttacaacacc ttcattatcg
    28681 atcagtacgt tttggggttt caaatctcgg tggatgattt gatggttatg agctaaagaa
    28741 atagcagaaa ggatctgctg cataatattt actgctgttt cataaggaac aggataatgt
    28801 gtttggatat atcgtttcaa gtccattcct ttgacgtatt ccatcaccag atactgcatg
    28861 ttgtcttctt caccaacatc gtaaacacta acaatgtttg gatgaacgag ttctgttgct
    28921 gctaaagctt ctctctgaaa tcgtcgaatc gcagtctggt cattttgaaa gtcaaatcgt
    28981 aagactttaa ctgctacatc acgatccaag attaaatcgt gcgccaaaaa tacatttgcc
    29041 ataccaccgc taccgatatt tccagtgatt tgataacggc catttaattt tttgcccaac
    29101 tcgatcatac actgtcctcc ttatattcga taagaagaac ggtgatatta tccgctccgc
    29161 ctgcttcatt ggcacgatca atcagctcag ttactttatg agacaatggg ccttcttgat
    29221 tgatgatcgt tcctatttct tcttcagaca gcatgttcgt caagccatct gaacataaca
    29281 gcagtcgatc ttttagttgc caaagatgag tagaaacatc tacttcgact gttccaggca
    29341 tgccgacaga acgtgttaaa atatttttcc ttggatggtt cactgccatt tcttcgctga
    29401 tttctcctga tttgactagt tcattgacta aagaatgatc ctccgtcaat tgcatgattt
    29461 tatcttcacg aatcaaataa gctctgctat ccccaacatt ggcaatcgtg aaccagtcat
    29521 ctgacagagc ggccgctacg attgttgttc ccataccgtt atattccggc tgttcttgtc
    29581 cacgctgata aatcagcata ttttcttctt gaatcgattg aatgaaccat tgggcgattt
    29641 tttcatcgtc aacagcttct tgtttttccc aagcttcgcc tagattcgtt accgccatct
    29701 gactggcaat gtctccggca cgatgaccac ccatcccgtc tgctaataca gcaagcttga
    29761 gacctgaacg gctggtaaat acactggcat agtcttgatt tgtgttacgt cgtcttccta
    29821 catctgattg atattcaatc tgcatttttt cacctcatta ctttttgcgc aaacaacaaa
    29881 tgaaaaatcc atctgtgtaa aactgatgcg gatacaaagt caacattttc tcttcgattg
    29941 atgattgtag cataggattg gtcaaaacat caatcctctc aaaatcaggg tgtctttcca
    30001 agaaagcaga aacaacgtct tggttttctt cttttaagat cgtacaagtg ctataagtca
    30061 gaataccgga agactttaaa gttggtgcgc agctttctaa aatttccaat tggatttttg
    30121 gtaaattcgc taattcatcc ggctgttttt tataacgaat atctggtttt cgccgaagca
    30181 gcccaagacc tgaacaaggc gcgtctacta aaatccgatc aaactgctct gcttcgaact
    30241 gtttactgac ttctctagca tccatctttt gagcgtagac agcagaagag acacctagac
    30301 gtgctgcatt atcttcaatg agtttgactt tgtgttcgtg tacatctaaa gcgaccactt
    30361 ctccaccgca tgacggatct aaaaaagaag caatatgcgt cgtcttacct ccgggtgctg
    30421 cacaggcatc taagacatga tgttcaggct cgatttgcat agacggcgct acaagcatcg
    30481 aactttcatc ttggatcgtc atgacgccat cgtggaacaa tgagctagaa gctaaatgcc
    30541 cttttttcgc tactataccg tatggactga cttggctttt ttcagctgtg atctcttctt
    30601 cttgcaaaac agtgatggcc tgatctctgg aaagtcggcg tgtatctact cgggcactag
    30661 catggctagg ctgatatagc gataaaccga gcttttcagt ttcttcgtat ccgatttgat
    30721 ccaccagtcg tttcgtcatc catagaggca ggctgatttt gacagaaagt ctttcgatag
    30781 gatcagcaat gccttgcaga tctggtgctc cttgacgctg ataattcctc aagacaccat
    30841 ttacaaattt ccctgtccca ggatttcctt ttacttttgc gatttcgacc gcctcgttta
    30901 aaatagcatg tgcagggact ttatctaaaa attctaattg gtatacagaa agataaagaa
    30961 gcgtcttgac ccagtcatcc actttttttg ctttagcgat caatggtgca acgtaaaatt
    31021 ccaatagtcg ctgatggcta atcgtaccat agatcaattc tgtaaataaa cccacatctt
    31081 tttgatttag ctcgctttgt ttgatcatct cattcaacaa aagattcgag taggcgccac
    31141 ccttgttcac tcgctctaat gtcagtaatg ccatatatcg tactgatttt ttcatttttt
    31201 tagggatttt tttcattatt tcacctgctg accaatctga acttgctgac cgcttccgtt
    31261 aaggaaatca tgtacggcct gttttccttt accagctggc tgtaattcat tgatggctaa
    31321 gacggtctgt ttaccgcaag caatccatag attttttttg tctttccgga tgatcgtacc
    31381 aggtgctttg tctgtagttt ctgccaatac ttcaaccgat aataatttcc agcgtatgcc
    31441 ctcataggtc gtgaatgcaa ttggccaagg acgcattccg cgtacttggt tgtcaatttc
    31501 ttctgcagtt ttatgccaat cgattgcttc ttgttcccgt gtgatgtttg gcgaaaaagt
    31561 tgcttctgac tcgtcttgag gtactggttt ttgtccatcc aaaatattgg gcaatgtttc
    31621 tagcaatagc tttcttccta aaaggctaag cttttcaaac atcgtcccta catcatcttg
    31681 tttagtgatt ggtatgcttt cttgcgcata gattccgcct gcatccattt ttttgatcat
    31741 ttccatgatc gttacaccag tttctttctc cccattcatg atggcataat gaacaggcgc
    31801 acctccccga tatttaggaa gtaaagaagc atggacattg attgccccta attttggtac
    31861 ttgcaataac ttttcaggca agaattggcc aaatgccgca gtgacgatca catcaggcac
    31921 caattcaatg atttcttcca tttctggcga accggagatt ttctctggct gcagcacacg
    31981 gataccgtgc ttcagagccg cttcttttac cggtgtcggc gtaattactc gtttccgccc
    32041 aactggacgg tcgggctgtg ttaccactgc ctggatctcg taacctgatt ctatcagccc
    32101 ttcaagaatc ggcacagaaa aagcaggtgt gcccataaat actagcttag tcatcaagat
    32161 gttcctccat atattcttca agttcttctt ccgggatctg ctgtatcatt ttctcaatga
    32221 acaagatacc gtctaagtga tcgatttcat gctggaaggc acgggctaaa tagccaaaag
    32281 ccgtcacttc tatctcttct ccgtctcgat cataataacg cacggtcact tcatctgctc
    32341 gcttgaccgt tccatagaca tgcggaatac tgagacaacc ttctacgtca aggctttcac
    32401 cttttgcttc gatgatttct gggttaatca gttcaaattt ctcgccttca tctacttcga
    32461 tcacagcaat tctcttgttt tgtcctactt gaggagcagc gatccctatt ccgtcattcg
    32521 caatcattgt ctcatataaa ttgtctaata aagcgattgt ctcgtccgtg attacatcga
    32581 ttggctgagc agttcttttt aatttatcat tagggtggat caatatagga tagcgcataa
    32641 tttggccctt tcttaaataa agtttaatgg ttcgttgtca attgccacaa aaagaccttg
    32701 tcgctgttct ttctggcttc cattcaaaat ttcatccaaa acatgaggaa gattcggttc
    32761 atgtttatat ttgatgatta gttgataata atatcggttt ttcactctca aaatcatgct
    32821 gggcgttggc cctaatagca agctttgagg gcttaacact tcttttagct gattggcaat
    32881 ctgaaagatt ttctttgccg ctacttgttc ttcaggatgg ctggcggtta ttttcacagt
    32941 aaagtaataa ggaggatagc ctccacgatg ccgtacatgc atttcctgct gataaaactg
    33001 ctcataattt tgttttttag ctaattctat ggcgtaatgt tgaggattga atgtttggat
    33061 cacgacttcg cctgcttttt ccgctcgccc tgctcgtcct gaaacttggg taagcaattg
    33121 gaatgtatgc tcactagaac gaaaatccgg taaattcagg gaggtatcag cattcaacac
    33181 cccaactaat gtcacttctg gaaagtccaa acctttagca atcatttgtg tccctaataa
    33241 tatatctgct tcttttgcac cgaatttttg taaaatctgt tcgtgtgccc cttttcttcg
    33301 agtggtatct acatccatac gcaaaatcct agcttgcgga taaagttctc ggagttcctc
    33361 ttctactttt tgagtacctg ttccatagta gcggatttta ttgccgccac aattaggaca
    33421 gcgattggga ataggttctt catgtccgca ataatggcag cgcattgaac gtgtatccat
    33481 atgcagtgta agagagatat cgcaattagg acatggaaga acaaatccac agtccctaca
    33541 catcacaaaa gacgaatatc ctcgacgatt gagcagtagg acagtttgtt cttttttgtc
    33601 taatcgattt tgtatttttt cctgcaaatt agcagaaaaa gtagaggtcc gatgattctg
    33661 aaactcttca cgcatatcta cgatctcaat agctggaagc tgtgcagctg ctttggctcg
    33721 gtggtttaac tgcaataact gataaacgcc tttttgagct cgtgctcttg attctaaaga
    33781 gggcgtcgcg cttcctagaa ctattgggca atgatgatat ttactgcgcc aaattgctag
    33841 atctctcgca tgataacgcg gtgtctcatc ttgtttgtaa cttgattcat gttcttcatc
    33901 gataatgatc agcccgatat ttttcagcgg ggcaaaaata gcagatcgtg cgcctactac
    33961 tacttgcgct tcttcccgct caatcttgcg ccattcatca tatttttcac cttgggaaag
    34021 tccgctatgt aagaccgcaa ctgattctcc gaagcgtcct ttgaatcgct cgaccatttg
    34081 cggagtcaat gcgatttcag gcactaacat aatagccgtt ttattttctg acaaaacatc
    34141 agcgattgcc tgaagatata cttctgtttt cccgctgcca gtgattccct ccagcaaaaa
    34201 gacctgatct ttttgctgct gacctgctgt gatgatttgt tcgacagcat ttttttgttc
    34261 tgcattcagt tccaatgccg tcgtttggtc aaatactcgg tctttataag ggtcgcgata
    34321 acgttctgat tctataaact ccagccagcc cttttctttt ccttgattca agacagcagt
    34381 actgattcct ttatttttga aataagcaat tggttcttct tggctcagtt cagataaaca
    34441 caaaagaagt tctttttgtt tcttggcatt ttgccgtaat tttgcccatt cttcttcgat
    34501 ttgcttttca gttaacaaag aacggaccaa acgaatcgtt tttactttat ttcgtgtatg
    34561 gacttcatat ttgatatcta ctaattgctc ttggcgccag cgaatcaatt gagaaaggct
    34621 gccttcttct tctgcttcct tccaggaaat cacttctcgc tgatcaaaca atacctgaac
    34681 ttctggtgtg tctgccaaag gatagatcaa tttatcatat tctgctttca tcacactcgg
    34741 aagcatcgtt tgtagacaag tgattttgaa tgcgtaagta atttttttca tataatcagc
    34801 taatgaaagt aattcttcat tgaccaccgg agcaaggtct agcaaacgaa taactgcctt
    34861 caaagatgga ttagctgatt cttctgattt ttggatagcc ataacaaatc cttggacatg
    34921 acgattgcca ttaccaaaag ggacttctac tcgcatcccg acttgcaaag ctgtttccat
    34981 ttcagaggga accaaataag tgaatggctg atcggtctgc atagtaggta cgtccacaat
    35041 gacttcagct gttaatgtca tggttcgttt cctccttttt ttgtcttttc ttatcaagcg
    35101 acaaaaagtt ccttgcctat tttactagag atcgatggat ttgtcttatc ttctgccaaa
    35161 tcctaacaaa aaattaacag cagataagaa aaaaaagaac tgtgtcaaaa agttcagaca
    35221 cagccttttc taccagacaa taagtggcga atgtttgaaa aggaaacagc tgggtttgct
    35281 tttcttttta gatgttcgct ctatttttct ttattacatt ttttgctctt cacggatacg
    35341 tgattccaat tcgtgttgtt cacgctcttt ttgtgcttga cgttcctctt cttccatctt
    35401 caaacgttca cgttttaatt caggatgtgg atcattgact acatttcctg catcgatttc
    35461 ttctaaagct tgaccgacgc tttttactga atcaaaagaa tctagagtag gctgtgcact
    35521 tgcatccaat tcatgcgcgc gtttacttgc taaaatcact agagaatatt ttgaatttac
    35581 acgatctaat agtgagtcaa ttgaaggttt taacatcata agactacatc tcctttaaca
    35641 ttttaatata tttaccgatt acgcgatcta ctcgaaaatg ttcactggca ataatgtttt
    35701 tgattcgttc aactgctagc ggcacttcat catttacaac agcatagtcg taaagagcca
    35761 tcatttcgat ttcttctttt gcaactttca ttcgttcttc gattacttca tctgcatctg
    35821 ttcctcggcc tacgatccgt gattttaatt ccgctaaatc tggcggagtc aaaaagatga
    35881 atacaccatc gggcactttt tctttgactt gttttgctcc ttggacttca atctccaaga
    35941 aaacatcttt tccttcatcc aatgtcttgt tgatatatga caaaggagtt ccataataat
    36001 tcccgacata ttctgcgtat tccagcatct ctccagcttc gatcattgat tcaaactctt
    36061 ctttgcttcg gaagaaataa tcaacgcctt cgacctcccc ttcacgcatt ttacgggtag
    36121 tcattgagat cgaatactga aaatcattat cctcactctc aaaaattgct tttcgtactg
    36181 tgccttttcc tacaccggat ggaccagaca acacgattaa taatccacgc tctgacatga
    36241 cgacgtcctt tcaactagtc tttttgtact tatcgtttat tttgcacttt ttttctgcaa
    36301 ctttcaaggt tatctttaat tatagctaga aattggtaaa aaagctaccc tgtaccaaga
    36361 ggtcgtaaaa aagctgtcct gcatcaagta ataagaacag ccaaacataa acagcttctc
    36421 atgtttttcg tttggttggg gttattatcg cagatgcaag cttttgaacg ccgtgtataa
    36481 gaggtcgtga agaagccgat tagtttcgag tatgaagaaa aattttgtga aaatagtttc
    36541 tcacattttt gcataaattt ggcttaatac
//
LOCUS       DAYNVV010000025        34655 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.025, whole genome shotgun sequence.
ACCESSION   DAYNVV010000025 DAYNVV010000000
VERSION     DAYNVV010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34655
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.025"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(61..1614)
                     /locus_tag="ACGXWR_001379"
     CDS             complement(61..1614)
                     /locus_tag="ACGXWR_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0802960.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            1762..3051
                     /locus_tag="ACGXWR_001380"
     CDS             1762..3051
                     /locus_tag="ACGXWR_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFK0802961.1"
                     /translation="MRYSTILISTFAALSLSLTINQTVHTEEIETAKWTETKWANVNR
                     ITFQDEFSSFNSGVAKLRKGQTATIKAKIDYSGDLAPILQSAVTFENVDPALSIGYDE
                     NTLTIQHKQAIFTFTVTLNQDLLKPALFTVKVSDGLPNDHHHLTPYSQRQTIEQDSAI
                     DSGGDLVEEPTDKPENENKPEVPPTENPDGEQKPEIEPGEEPDTETQPEPDNESKPEI
                     TPGEKPDVDPEEKPDVTPEPDTDSGNQTVPETNPDTDNETENPEKPEAAPEEKPDVTP
                     EPDTDSGNQTVPETNPDTDNETENPEKLEVDPEEKPDVTPEPDTDARDQGIPEKINKK
                     TIQEDGKKESKKSNLAILKINEEQLNKKSRIFDSAQSAETLKSSKDTTFASPETKNKQ
                     LPKSGESQNKVILWSGIILLSIATMLSAKRFKQNRSL"
     gene            complement(3177..4256)
                     /locus_tag="ACGXWR_001381"
     CDS             complement(3177..4256)
                     /locus_tag="ACGXWR_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFK0802962.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVIDFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVIALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(4365..4805)
                     /locus_tag="ACGXWR_001382"
     CDS             complement(4365..4805)
                     /locus_tag="ACGXWR_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFK0802963.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTSLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTPQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(4862..5272)
                     /locus_tag="ACGXWR_001383"
     CDS             complement(4862..5272)
                     /locus_tag="ACGXWR_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFK0802964.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(5453..5887)
                     /locus_tag="ACGXWR_001384"
     CDS             complement(5453..5887)
                     /locus_tag="ACGXWR_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFK0802965.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVSFEERKQLFEKYM"
     gene            complement(5987..6835)
                     /locus_tag="ACGXWR_001385"
     CDS             complement(5987..6835)
                     /locus_tag="ACGXWR_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFK0802966.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAVLGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLFFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFVFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            7224..8990
                     /locus_tag="ACGXWR_001386"
     CDS             7224..8990
                     /locus_tag="ACGXWR_001386"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HFK0802967.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETRRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVRDHLDYLTDLGVNGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVYDREDKLYFTRELEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            9092..10351
                     /locus_tag="ACGXWR_001387"
     CDS             9092..10351
                     /locus_tag="ACGXWR_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFK0802968.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            10498..11799
                     /locus_tag="ACGXWR_001388"
     CDS             10498..11799
                     /locus_tag="ACGXWR_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0802969.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            11802..12653
                     /locus_tag="ACGXWR_001389"
     CDS             11802..12653
                     /locus_tag="ACGXWR_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HFK0802970.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            12666..13481
                     /locus_tag="ACGXWR_001390"
     CDS             12666..13481
                     /locus_tag="ACGXWR_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HFK0802971.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            13632..14798
                     /locus_tag="ACGXWR_001391"
     CDS             13632..14798
                     /locus_tag="ACGXWR_001391"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFK0802972.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            15028..15675
                     /locus_tag="ACGXWR_001392"
     CDS             15028..15675
                     /locus_tag="ACGXWR_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFK0802973.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            15759..16703
                     /locus_tag="ACGXWR_001393"
     CDS             15759..16703
                     /locus_tag="ACGXWR_001393"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HFK0802974.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            16838..18289
                     /locus_tag="ACGXWR_001394"
     CDS             16838..18289
                     /locus_tag="ACGXWR_001394"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HFK0802975.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            18310..19146
                     /locus_tag="ACGXWR_001395"
     CDS             18310..19146
                     /locus_tag="ACGXWR_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFK0802976.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            19146..19805
                     /locus_tag="ACGXWR_001396"
     CDS             19146..19805
                     /locus_tag="ACGXWR_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFK0802977.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSIHQS
                     I"
     gene            19931..20620
                     /locus_tag="ACGXWR_001397"
     CDS             19931..20620
                     /locus_tag="ACGXWR_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802978.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PKDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            20626..21582
                     /locus_tag="ACGXWR_001398"
     CDS             20626..21582
                     /locus_tag="ACGXWR_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HFK0802979.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            21626..22138
                     /locus_tag="ACGXWR_001399"
     CDS             21626..22138
                     /locus_tag="ACGXWR_001399"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFK0802980.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSGVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(22394..22942)
                     /locus_tag="ACGXWR_001400"
     CDS             complement(22394..22942)
                     /locus_tag="ACGXWR_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFK0802981.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(23031..24212)
                     /locus_tag="ACGXWR_001401"
     CDS             complement(23031..24212)
                     /locus_tag="ACGXWR_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside transporter C-terminal
                     domain-containing protein"
                     /protein_id="HFK0802982.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(24448..25956)
                     /locus_tag="ACGXWR_001402"
     CDS             complement(24448..25956)
                     /locus_tag="ACGXWR_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HFK0802983.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATCLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            26115..26306
                     /locus_tag="ACGXWR_001403"
     CDS             26115..26306
                     /locus_tag="ACGXWR_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802984.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            26509..27426
                     /locus_tag="ACGXWR_001404"
     CDS             26509..27426
                     /locus_tag="ACGXWR_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coiled-coil domain-containing protein"
                     /protein_id="HFK0802985.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            27419..28492
                     /locus_tag="ACGXWR_001405"
     CDS             27419..28492
                     /locus_tag="ACGXWR_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802986.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            28640..29158
                     /locus_tag="ACGXWR_001406"
     CDS             28640..29158
                     /locus_tag="ACGXWR_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0802987.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            29139..29531
                     /locus_tag="ACGXWR_001407"
     CDS             29139..29531
                     /locus_tag="ACGXWR_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HFK0802988.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVVFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            29607..30542
                     /locus_tag="ACGXWR_001408"
     CDS             29607..30542
                     /locus_tag="ACGXWR_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFK0802989.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            30675..31454
                     /locus_tag="ACGXWR_001409"
     CDS             30675..31454
                     /locus_tag="ACGXWR_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFK0802990.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            31447..31764
                     /locus_tag="ACGXWR_001410"
     CDS             31447..31764
                     /locus_tag="ACGXWR_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFK0802991.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            32008..33618
                     /locus_tag="ACGXWR_001411"
     CDS             32008..33618
                     /locus_tag="ACGXWR_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFK0802992.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            33775..34623
                     /locus_tag="ACGXWR_001412"
     CDS             33775..34623
                     /locus_tag="ACGXWR_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFK0802993.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT        11456 a         6167 c         6707 g        10325 t
ORIGIN      
        1 tcttgataca taaatccgga ggttgttaat aagcattcgg atttatgtat cttatttggt
       61 ctaggaagta acttgatttt cttttttcga ttgatccatg agtgcttctt cttttaattc
      121 aaagatatat tctgagatcc tcataatcac ttttttccag tcttctggtg tgatgattcc
      181 ttttaaaata tagatttttt tgatatgaga aggcaattgt ttcaaagggc agtcgctgat
      241 aacgatgttg cagttctcca taaaatcatt ttgtattttg atcgattcat ttgaaaaaat
      301 ttgttctatc ttaacgatca gatctttact gatataaaaa tcacgcgtat agttcacacc
      361 aatcacaatt cgcggctgtt ttttgtagcg atcatacaaa tgtactaggt cttcaaccat
      421 ccattgcaca ttttcctttt ctaaaataac tggtaacaag tgttgatttt gttctctgaa
      481 atccatataa aattgttcaa tggcggtttg gacttctttc aacacgctat gttcttgata
      541 aagcatgaaa gtaggaaggg gcgtatttgg ttgattgaag ttaagaaatc cattataaag
      601 tttatttcgt gcgaatgcca atgagtaaag aatcttttct ttttcaggta taaacaaatc
      661 aaatacagta caaaaggact ccaccatttc tcttgaataa agaacatgag gaacgtttgc
      721 tttttttaaa agtttgtatt gctccaagct tgtttcttcc gattcgattt tcgtgataga
      781 aagtcgagct aaaatattca ctaagatgcg ttgttcgcga caaattggca gattaggtcg
      841 caaaatatct acagagggat caataaaaaa gtcaatatat tcatactctg tgaattcttt
      901 ttgtacgtct ttcacagaag ttgcaggaaa attctcttta catattttta atagaaaata
      961 taatttatct atcataccgc tatttagtcg gtcaagtact tcttttttaa aaaaagtatt
     1021 catcataaaa gccactactt gcggatcttc atcataaaat tctgtagcag tacttgaaaa
     1081 gatgttccaa taaatatcta atgctgcata ttgaatttgt acctcttttc cagaaaaaga
     1141 ctttctgcca ttattagaaa aggagataga caaaccgtac aatgctaaaa atgcattaat
     1201 ctttttcatt ttcgtataca aataagaggc actatagttt gtttgctgac ttaaactgat
     1261 aatcgaattt gtctgacagc tgaacaaaga agtcaagatc tgataactga ctgattcgtt
     1321 gcagtatctt ccaaatagac gataatagca gtaagccgga tcaattcctt caaaattcaa
     1381 ctttaaaaaa ggtttttgct tatcaatatg cagttctgtt agattgagac gctcaaagtc
     1441 ttgttctaat tctttgatgt atagtaaaaa atttgattca gacatatgga aatgatctgc
     1501 taaatattgt gtagtaataa agaaacgatg ttcagatagg aaaagaaaaa tatctaattt
     1561 tgtattgctt tttttcttca agagaaacgt tttaatcgct tcttgagttt gcatgaaaga
     1621 ggctcctttt tacttaaatt gttaaaactt gaaaatatta ctgttttttt cataaattta
     1681 gacaaaaaaa cagtaaacat ataggtagaa tctctactat cttatttctt gcatacaaaa
     1741 aaatcaagga gtgagagagt tatgagatat tcaaccatct taatatcaac atttgcagcc
     1801 ttaagcttat cgcttactat aaatcagaca gtccacacag aggagataga aacagccaaa
     1861 tggacagaaa ccaagtgggc caacgtcaat cgaattacct ttcaggatga attttcatcc
     1921 ttcaattcag gagtcgcaaa attaagaaaa ggacaaacag cgaccatcaa agcaaaaatt
     1981 gactattcag gagacttagc acctatacta caatcagctg ttacatttga gaatgttgat
     2041 cccgctttgt cgattggcta tgacgagaac actttgacta tccaacacaa gcaagcgata
     2101 tttaccttca ccgttacatt aaatcaggac ttgttaaaac cagcgctttt tactgtcaag
     2161 gtatcagatg gactaccgaa cgatcatcat catttaacgc cgtatagtca gcggcagaca
     2221 attgagcaag attcagctat cgactcagga ggagatcttg ttgaagaacc aacagataaa
     2281 ccagaaaatg aaaataagcc agaagtaccg cctacagaaa atccagacgg agaacagaaa
     2341 ccggaaatag aacctggaga agaacccgat acagaaactc aaccagagcc agacaatgaa
     2401 tcaaaacctg aaataacccc tggagaaaaa ccagatgtag acccagaaga aaaaccggat
     2461 gtgactccag aaccagatac ggattctgga aaccaaacag taccggaaac aaatccagac
     2521 acagataatg aaactgaaaa tccagaaaaa ccagaggcag ccccagaaga aaaaccagat
     2581 gtaactccag aaccagatac ggattctgga aaccaaacag taccggaaac aaatccagac
     2641 acagataatg aaactgaaaa tccagaaaaa ctagaggtag atccagaaga aaaaccagat
     2701 gtgactccag aaccagatac ggacgcaaga gaccaaggaa taccagaaaa aataaacaaa
     2761 aaaacaattc aagaggatgg aaaaaaagag agtaaaaaat caaatctagc aattctaaaa
     2821 ataaatgaag agcagctgaa taaaaaatca cgaatatttg atagcgccca atcagctgaa
     2881 accttaaaaa gtagcaagga tacaaccttt gctagtcctg aaacgaaaaa taaacagcta
     2941 ccaaaatccg gagagtcaca aaacaaagtt atactgtgga gcggaatcat tctattaagt
     3001 atagcaacaa tgctttctgc aaaaagattt aaacaaaaca gatctctcta acatttgaat
     3061 aatgtctgtg aacgcatttt tcaaataaaa agaaatatcc agaaaacgac cccaaaatac
     3121 cagattgaaa tctgatattt ggggtcgttc atactttatc tttcttcata tttattttaa
     3181 gggatatctg tttcttttgg aagatggttc gggatctttt tcactttcaa tacatctaaa
     3241 aagaaggtaa agatcggaat gccgacaatc aagccccaaa cgccaaagaa ccgttcgcta
     3301 acaagtaaga ccacaaatgt ataaaaaatc ggcagttctg ttttgctgga catcaacttc
     3361 ggattcagca cataagactc aattagatgg acaatcaaaa tcgtaatcag gatataaaca
     3421 acatctcgga tgcctccttg ggaataagct atgaaagata gaggaataca agaaatgata
     3481 acacctgcta ctgggatcag acttaaaatg aaaatcatga tcgctaaact cagcagctga
     3541 tgaaagccaa atacagccaa ggcgattgta gtgagcaacg tgtttaaaag agcgataaca
     3601 aattgagctt ctaataccaa accaaatgta ttgacaaact tatcggcaaa atagtaaata
     3661 tcttgaaaga accaagaaaa ttcacttttt aaaaacaatc ttgagaatac aattgttttt
     3721 ttcttttcaa tcataaaaaa gaaacttaag atgaatgaca tagcaaacgc cactgccatt
     3781 tttcctatat cctgtaaata gccaagcgca atcgaagcgc cattttgaag ctgttcaaaa
     3841 aaatcgtttc gctcaatata agtatggata tattgtaaaa caggatctgc atcttttggc
     3901 tgatgctcgt aaaaatcaat aacggactgg atcatatcaa atgtttgatg aataagcatc
     3961 gggatatact ttgtgaatgc cagatagata aggtaaacga tcagtgtata aatcatgata
     4021 gctaaaacac ctgtagggat tcggacaaat cgctgaatga tttgaacaag atgaatcatc
     4081 aaataagtaa agataaatgt gagcaaaatg gttgtaatca tacttctaac taagaaaaga
     4141 acaaaaacga caaataataa aacagtgaga cggcgtattt tttcattcgc caaaaaacgc
     4201 tgataaacgg tcaaatcgac aacctccaaa taacaaaaaa taaacacgtt attcattata
     4261 tgatggaata tgaaaataag aaagagaaag agcaaaaaga aaaaccgcta aatgacgtta
     4321 tcttatgagt tggttttcct cataaaatcg ttcatctagc agtttcagcc ctttttctgg
     4381 tcttgatgaa aattatctag catttttcgg gtcagatgtt gcagtgtatc caattcttcc
     4441 tgttcaagtg gaagataaga cttgatcttt tgtggaatac cttctgcttg tttttgcaac
     4501 gcagcacctt gaggagtcag cgtaacattt acgattcttt catcacccgt ttcacgctga
     4561 cgattaatat aatttttttc tgctaacttt tttagtaagg gagtcagcgt accagaatcc
     4621 agacacaaat catttcctag ctctttcact gaagtctttt tcttttccca taaaactaac
     4681 atcacaagat actgggtata ggtaagattc agcggcttga ggagggaagt gtagtgtcta
     4741 atgatttcct tagaggcggc atataaagga aaacatactt gattaactaa atatagatct
     4801 tccatttttc cacctccgct gttttactat agtgtatcat agcggattta cacaaaaaag
     4861 tctattcact aactgctttc agagtaactt ctatatttcc agctgtagct tttgaatacg
     4921 gacacacttt atgcgctgcc tctaataatt cttgcgtttc ttccagagaa agaccttcga
     4981 tagatccttc aatctctaca cctaagacaa agctcgtttc actttctgaa taaagggaaa
     5041 cttgtgcact gacagtagaa gccccagaga tatttttttg ctgtttgatc aattctaatg
     5101 cactgttaaa acatgcactg aaaccagctg caaacaattg ttcagggttg gttgcatttt
     5161 cgacgcgttt accaggagct gcaatattca attcgaatgt acgatcggga ttatgaactt
     5221 ctccagagcg tccgcctgtg ttgatcattt tcgtagaata catttttttc ataaaattac
     5281 cacctttaat tatattttat acaattgaat tttacacaat ataattgtgg aaagcaaaga
     5341 aatggattgg cataagataa ataagagaaa gcacatgaaa cagacgcgct ttctcgaata
     5401 gcaaacatat acaaaaaaat atcagagaca aaaactaatc tcatcataaa cattacatat
     5461 atttctcaaa aagttgtttt ctttcttcaa aacttacttc acgatggacc tgatgaagca
     5521 tccataaata accaaaagga tctctgaaca ttgagttagt cacaccaaag tccatcattt
     5581 ctgtcatttc ttgaatctct acacagccat ttcgtaatgc tttattatgt gtgtcctcga
     5641 tatcagagac gatgatattg aaccagatcg tatttggatg ttcagcagta ggagcagtca
     5701 aaccaagaga cgtgttttca tccagcatat ggaatctcgt gccatacaag gtaaaaatga
     5761 cttcattatt gcctctaggg taatctgttg cctcaatcag ttgtatttca tcaaagattg
     5821 tttgatacag ttctagtgct ttcaaactat catttaatac aaaatctatt tccgttcctt
     5881 tatgcataaa gatctcctct ccttttcagt cgaacagtta ctagattctt ttattatacc
     5941 agttaaagaa aacgcattca aaaaaatagc ggatttactt accaactcat tcgattggat
     6001 gataagtaaa tccgcgtccc attacttctg ctacgctgct gacaatgaca aaggcacttg
     6061 gatcgatttc ttctatcaat ggtttcattc gggaaaattc atgatcagtc acaacgatca
     6121 ataaaacctc ttttgacttt cgattatacc cgccttttgc ctctagcagg gtaaggccac
     6181 gtccaatctc agcacttaag cgaaggcgga tgtcttccaa ataatgttca ctcatgacca
     6241 taacagattt ctttcgattg atacctgttt cgatataagt catgacaatt gaagtgattg
     6301 caatagataa aatagcataa agaaactctt ctattccaaa aacaaacaga ttaagagaaa
     6361 caacgaatgc gtctgtaaaa aataagccaa tcgaagtatt caagtggaaa tattttttaa
     6421 aaatgagggg agggatcgtc gtaccgccgc tagaagagtt gtttttatat aaaatcgcaa
     6481 ctcctaaagc aaaaatcgca cttccaaaaa tgacagacaa caaccgatct gaagtaatca
     6541 ttgtttctgg aactattgca atgattaaag gaaaaaacaa gcttccgaaa agtactttaa
     6601 aaaagggttt tttacctaaa aatagaagag ctagtaccaa cataacgata ttcaacacta
     6661 aaataactat agctcggtca aatcctaaaa cagcttccag taatattcct agaccgctga
     6721 cacctccagc agcaatatga tgaggcccta aaaacatatt gatagcgact cctaatatga
     6781 agagggcaaa aataatctta atgtatgtcc atataaattg tctcgtttct ttcatttatc
     6841 cacttcctta attcattaat aatactctta tcttattata acttactttt caccttaagt
     6901 taactttaat taataaaaaa attaggctag tctaaattat tatgtttcat tcttctagaa
     6961 tatacttcta cgttaaaaac tgttaaaaaa cttttacttt agaaaattgg agaaattgat
     7021 cgcttaagat aaattcagga cactaaatag tacaggaagt agattaaaac ttttaaaagt
     7081 tttaagtcta tctatttggc aagtttaaaa aataaaaatt cggtatcaaa aaactgttac
     7141 cgataacatt tttgaaagcg ttgtcttttg tttctctatc acttatagtg atgacgtcat
     7201 attaaaacac aaggaggaaa tcaatggata cagctgcaat ttatcatcga ccggaaagtg
     7261 aatatgcatt tctatatacg aatacaagat ttcgtattcg gcttcgtact aggaaaaatg
     7321 atatcaaaaa agtatatgtg ctttgtggag atccatatac cataacaact gaaaaatggt
     7381 atcaaaaaca acgaccaatg aaaaaatgtc taagtaccaa tgttcatgat tattgggaaa
     7441 ttgaagtgac gagcgaaaca aggcgcttac agtatgcgtt ccatgttgtt ggggaagata
     7501 acacggactg tttttacggt gatcaaggaa tttttcctta tcgagaaaat gtgattactg
     7561 aaccaaattt ttattttcga ataccttatt ttcatcaaat cgatcgattc actattccag
     7621 aatgggtaaa agaaacagta tggtatcaaa tttttcccga aagatttgca aacggggaca
     7681 aagcaaatga ccccgaacac actttacctt ggggaagtaa agatccagac cgagaagact
     7741 tcttcggggg agatttgcaa ggtgtgaggg atcatttgga ttacttgacg gaccttggcg
     7801 tcaatggcat ctatttttgt cccatattta aagccacatc caatcataaa tacgatacga
     7861 ttgattatta tgaggtggat cccgcttttg gcgataaaaa acttttaaaa aacttgattg
     7921 atgaagcaca taaaagaggg atacgtatca tgttcgatgc tgtattcaat catatgggtg
     7981 tccattcacc acagtggcaa gacgttctca aaaacggaga aaaatcgatc tataaagact
     8041 ggttccacat ccgttttttc ccagtagatt cttatcagat gactgactta ccagaaactg
     8101 ctgaaaatat cccatatgat acttttgctt ttactccatt catgccgaaa ctaaatacag
     8161 caaatccaga agtgcaaaaa tatttgctgg atatcgcaac ttattggata aaagaattcg
     8221 atattgatgg atggcgtctt gatgttgcta atgaagtcga tcatcatttt tggaaaaaat
     8281 tcagagaagc agttacagaa atcaaaccag acatctatat ccttggagag atttggcatt
     8341 cctctcaagc ttggctgcaa ggggatgaat tccatgcagt gatgaattat gcattcacag
     8401 attcgattaa agattatttt gcaaaaaaga aaatcacagc ttcacaaatg gtcagtggaa
     8461 tgaatcatca gcaaatgctt tacagagatc aggtgaacga aggaacattc aacttattag
     8521 attctcatga tactgccagg atcttgaccc tttgccaagg taacaaagaa ttgatgaagt
     8581 ctgtgatggc ctttatgttt cttcaaaaag ggtctccttg tatctattac gggacagaaa
     8641 tagggatgac tggtgaagat gacccggatt gccgcaaatg tatgatatgg gagaaggagg
     8701 aacaagatct agagctattc ggttttataa aagaacttgt ttctctaagg aaacagttgt
     8761 ctaagattat ttctgaaggt tctactcagt ggctaatagt atatgatcgt gaagataagc
     8821 tctatttcac acgggaacta gagggacaga tcatctatgt ttactttaat cagtcaaaag
     8881 aaccttgggt agtagaacag gaaaatgagg tgattcttag tcaaaattgt cagttgttag
     8941 aagacgggaa agcagagata cgacaatacg gatttttgat catgtgttga aaactgttac
     9001 cggtaacaac aagaaagcgt ttgcaaatga agatttgtgc ccattataat aagggtgtaa
     9061 cagcacgttg aatacacagg aggaaatgaa gatgaaaaaa agaagtgtga aacagttggg
     9121 tttagggtta atctctttag gaatcttagg cggattagcg gcttgtggca atggtaactc
     9181 ttcagcagaa ggggaagccg atgaaggaaa aacgttaaca gtttccgttg attctggata
     9241 taaagattat ataaacgaaa taaaaaacac tttcgaaaaa gaaaacgatg tgaaaatcaa
     9301 gctagtagaa aaggacatgt tcgatcagtt ggaatcatta gcgttagatg ggcctgctgg
     9361 aaagggacct gacgttatga tggcagcata tgaccggatc ggtgcgttag gacagcaagg
     9421 acatctggcg gaagtaaaac tgggaaatga agcagcttac gatgaaacag acaaagccca
     9481 agtgacttat gatggaaaaa tctacggaga acctgcagta atcgagaccc ttgttttgta
     9541 ctataacaaa gatttagtcg atacagcacc atcaacgttt aaagatttgg agaatctatc
     9601 caaagacagt cgttttgctt ttgagtcaga agcaggaaaa aatacaggat ttttagctaa
     9661 atggactgac ttttattatt cctatggttt aattgcaggt tacggtggct atgtatttgg
     9721 tgatgatggc acaaatcctt cagatatcgg tttgaataat gcaggtgctg tagaaggaat
     9781 ctcttatgca acagattggt tcaaaaatgt ttggccaaag ggaatgcaag acataaaaag
     9841 tgcaggagac ttcgccagcc agcaattcat gtccaataaa actgcagcaa tcattgacgg
     9901 tccatggcaa gcgcaaacat acaaagaaaa caatatcaat tatggtgtag ccaaaattcc
     9961 tactctaaat aatggacagc cttatcaacc gtttggcgga ggaaaaggat gggtagtcag
    10021 caattatgct aaaaacaaag acctctctca aaaatggctt gattatgtaa cgaatcagga
    10081 aaatcaagaa aaattctttg aaatggtaaa tgaaatccct gcaaaccaac aagctaggga
    10141 aacagcaaag gctaaaaacg atgaattaac aacagctgtg attgaacaat atgaaacagc
    10201 tcaagcgatg ccaaacatcc cagaaatggg cgaagtttgg acaggtgcag aaaacttgat
    10261 gttcgatgca gcatcaggtt caaaaacacc aaaagaatcc gcagatgaag cagtaaaaac
    10321 aatcagtgaa gccatagaac aaaaatactg attaaaatga taaccgtcca tttttataaa
    10381 aaatggaaca ggtgcttcag ataaaagtgg caagagcgag atggaaaatt atcttgctct
    10441 tgttgccatt atcttaaaag cagtttgcgg tttagcaagt ttagaggggg cattcagatg
    10501 cagcaagata aaacaagcaa tatcaacgaa aaaaaaatca cgctttgttc acttattcca
    10561 gggatggggc agtttgtaaa tggccaagct tttaaaggta tcgttttttt cgccatattc
    10621 gtcctattca ttggtcagat gcttctgggc ggatttcatg cattggtagg attggttact
    10681 ttgggaagta taccaatgga agatcattca ttatttattt tgattgaagg cactttgcaa
    10741 ttcatcatta caatcatttt cttgattttt tacggtttga atcttttaga cgcttatcga
    10801 gtagcgaaga tgcgtcaaga gggcaaaaaa atcaatcgga cgatgaagga agtcatacat
    10861 aatataggtg atgaaggttt tccttatcta ttgacacttc ccgcttatct tctcatgatt
    10921 tttacgatca ttttcccagt cctagttaca ttgttcactg catttactaa ttatgacttc
    10981 aatcatattc caccagccag tttaattgat tgggtagggg ctaaaaactt ttttagtatc
    11041 ttctttttaa gctcatatcg taatactttt tttgcagtct tttcgtggac cgtgatttgg
    11101 actttatgtg caacaacttt gcaaatcacc cttggtattc tcacagcggt tgttgctcac
    11161 cagaaattta ttaaattcaa acgtattttc ggtatcattt tcttattacc atgggcggtc
    11221 ccagctttta ttactatcat gagtttttcg aatatattca acgatagcgt aggtgccatc
    11281 aatactcaag tgattccttt cataaaccag cttccttttg tagatatcag tgcaatctct
    11341 tggaaaacgg acccgaactg gacgaaagta gcaattatct tagtgcaggg ctggttagga
    11401 tttccctata tctatgtgat ggttacagga atcttacaat cgatttcaga agacttatat
    11461 gaagcagcaa aaatcgacgg agcaaatgca tggcagcgct tttcaaacat cacgcttcct
    11521 gctgtcttcc tagtggcagc gccaacattt attacacagt atacggggaa tttcaataat
    11581 ttctccatga tctatctgtt taacaatggt ggtcccggaa gcgtaggcgg aggagctggt
    11641 tctactgata ttcttatttc ctggatctat aaacttacga ctggaacttc tccgcagtat
    11701 tctatggctt cagcaatcac gttgattatc tccgtcatcg ttatctgtgt gtcattgctg
    11761 gtatttaaaa agacaaatgc gttcaatatg ggggattaac aatgaaaaaa tttcattcga
    11821 gtgctcgatt ccaaaaacga ctttctcact tttttactta cttttttctt ttaatactgt
    11881 cagtcattat catctatccg cttttgatca cagcaagtac tgccttcaag tcaggaaata
    11941 ttgcagcttt tagtttagat ctttcaagtg actggacttt aggaaacttt actcggctat
    12001 tcagtgaaac actttacggg acttggtata aaaatacatt gatcatttct gtcctaacaa
    12061 tgatcgtaca agtgactgta gtaactttgg cgggctatac ttatagtcgc tatcgtttta
    12121 tcggccgcaa atcaagtttg atgttctttt tagtgattca gatggtaccg actatggcag
    12181 cattgactgc cttttatgtc atggctttct tattagaagc gctcgataag tactggttct
    12241 tgacaatgat ctatataggc ggtggaattc caatgaatac ttggctgatg aaaggatact
    12301 ttgacactgt accaatagat ttagatgaat ctgctaaact tgatggggca gggcatttca
    12361 ggattttttt ccagattgta ttaccgcttg tcaaaccgat gctcgccgtt caagcattat
    12421 gggcttttat gggacctttt ggggatttca tgttagctaa gttcctgctt cgaacacctg
    12481 aaaatcagac tgttgctgtc ggcttacaaa catttatttc tgatgtgaca aaccaaagag
    12541 tctctctttt tgctgctggg gcaattttga ttgcactacc gatttgtcta ttattcttct
    12601 ttttacaaaa gaactttgtt accggcctga catctggcgg aacaaaagga taggagcaga
    12661 gtatcatgca aacatttccg ttaaactatt tttccgcatt acgtacgcca actcaagtgt
    12721 ttgcgggacg caaactatta tcatggccta aatttttctt gatatttgta tttttagttt
    12781 ccttgatggt catgcctgtg actctttttt atgccaatca gatccaagcg attccattag
    12841 aacaatttct atccgttcat tcgctgatcg atgaacaagg aacccaaaaa ttttctgaac
    12901 ttgaattatc tgaaactggg ttacaagcat cgcaacaaac gatagctgtg acccctgaaa
    12961 ttttggtagg tgtgtcttta tctgagaaac aacaatccga tcatggaact tttattgatt
    13021 ttgagaagga acaatgggtg atccaacaaa aggataaatc tggtatacgc cgctatacga
    13081 tgaattatag cccatctttc caaccagatt ctgtacgtac gcccgaagat ttccaacgat
    13141 ttttagaaag agaattttat gccagtaatc gtccaacaat cattttatct tatagtttaa
    13201 gtcttggtct tgtcctattt gtcatgacga gtctcatttt attcggggct tcctttttct
    13261 tgtggatgac aagaaaaagc caactttcat ccattcatac attcaaagag agtgcaaatt
    13321 tgatgctgaa tgttatggga ataggttcca tggcagcagc agttgtaggg tttatccact
    13381 ttgactttat cttgatgcta agtgtccaaa caacgataac tgtcttgctg cttttatggg
    13441 tttttgtcaa aacaagattc aaagataagc gtgtcgaatg acaagtttaa gcgatttatg
    13501 cgacaatgaa tgtgaaaaaa atgaaaaata aagtagtttt tgaaaaattt ctgaaaaaat
    13561 taaacttctt agttgattct tttctttttt agtattaacg taatagggta gtttttttaa
    13621 ggaggaaaat catgttagag aaaactttat acaatcaatt attttcacgt tctttctcgc
    13681 tccctgtcga agtaaattat tgggacggta caacgaaaca atacggagat acggacactc
    13741 ctccccaaat caaaatcaat atccatgaag aaatcccaat gaaagagatt acaagtaacg
    13801 cttctttggc actaggagaa gcctatatgg atcatcgaat cgagatcgag ggaagtatcc
    13861 aagcattgat caacgatgct tatcagcaag caaacagctt tttacgagga aaagattatc
    13921 taaaatggct gccaaagaaa gaaaaacata cgaaacaaaa aaacaaagaa gatatccatg
    13981 cgcattatga cttaggtaac gacttttata aactttggct agatccaact ttgacttatt
    14041 cttgtgctta tttcaataca cctgaagata cgttggaaca agcacaaatc aataaagtcc
    14101 atcatatctt agacaaactc tttatcaaag aaggcgaaac gttgcttgat atcggttgtg
    14161 gctggggaac attgatgttc actgctacca aagagtataa tgtcaaggca actgggatca
    14221 cactaagtga agaacaatac gatttgatta ccaaaagaat aaaagaagaa catttagaag
    14281 ataaatgccg tgtattatta atggattacc gcgaactaaa aggcgaaacg tttgatcata
    14341 tcacaagtgt aggtatgttc gaacatgtag gttctgaaaa tcttgaaggt tatttcaaag
    14401 tggtaaaaga tttattgaaa ccaaaaggaa cagctttgat ccatggaatc agccgacaac
    14461 aaggcggtgc gacaaatgct tggatcaata aatatatttt ccctggcggt tatgtccctg
    14521 gtgttactga attagttgat aatattacaa aaaacgattt gcaactgatt gatttggaaa
    14581 gcttacgtcg tgactaccaa ttgacattag aacattggac aaagaatttt catcaagtcc
    14641 aagatcaagt cacgaaagaa atgggtgatt ccttctatcg aatgtgggat ctatatttac
    14701 aagcttgtgc agcttcattt gaatcaagta atatcgatgt gattcaatat ttgcttgttc
    14761 aacctggaaa caatgacatc ccaatgcatc gtgcataatt gaggcaaaag tactgtttaa
    14821 agactattta aaaagaagct aagttttatg atgctccaga agtgaacttt tttgtctaac
    14881 ttctaggatt gtctctaaag cttagtttct ttttctttat attttcataa taaaagtttg
    14941 gttctttaat ttttaaacat gacagaaaat tttttcttcg ttatacttgt aatagaatac
    15001 tattttataa caaaggggat cgaatcaatg aaaaaaactg ttatttatac tagtttattt
    15061 gcagctttgt ttttagctgc ttgtcaatca aataccaatc aaggcacatc tgggaatacg
    15121 tcttccagta gcgaacagcg ctcttcacag gtatcggact cctcaacaaa agcaagcaca
    15181 tcttcgtcta gccagacaaa aagttctagt gaagcaagta ctcagtcaga tatcaaagtg
    15241 tctgcagctc gtgcgatcga attgttccaa gataaatacc cagatactgc aattactagt
    15301 ttggaattag atagtgattg gggatcttac ttctacaaga tagaaggtgt cgatgatcaa
    15361 aaagaatacg aagcaagaat tgatgctcaa aatgaaaaaa tggagacaga gaatccagaa
    15421 actctagatc gagatgaaca aaatggtcaa aagaaaaaag aagatggtct ggatgttgat
    15481 aaattgatca cgattgagga agcagcaaaa atcgccgtcg acaaagtagg aagcggtacg
    15541 gcaacagatt gggatttgga taaagattta ggtactactt attgggaagt caaagtaaaa
    15601 gacggcaatc aaagtacatc agtcaagatc aatagccaaa caggcgaagt actgtcaact
    15661 gaacaagatg attaagaatt tcttcggaaa acaagagttg atttttcttt tagtcatgat
    15721 acactagaca aaataacttg tttgaaggag cgatttactt gagtttagaa acgacctttg
    15781 ccaatcatat ctttgccaat cctttgatga atgcatctgg tgtccactgc atgactaccc
    15841 aggaattaga tgaactggct cattcagaag caggagcatt tatcactaag agctgtacga
    15901 tcaatgaacg aaaaggaaat cccgaaccac gctattttga tgttccttta gggagtatca
    15961 attctatggg acttccaaac ttaggttttt cttattatct agagtatgct cttgcgtatg
    16021 aaaaagtgca ggaaaaccaa aatcaaccgt tatttttttc cattgccggg atgagtgtcc
    16081 aggaaaactt ggaaatgctt gagaaaatag aaaaaagtgg gtttaatggg atcactgaat
    16141 taaatttatc ttgtcccaat gtgcctggaa aaccacaact agcttacgat tttgaggcca
    16201 cttatgaaac actgaaagaa gtattcagca tcttttctaa gccgctagga atcaaattgc
    16261 ctccttattt tgattttgct cattttgatc agatggctga tatcttgaat cagtttccat
    16321 tgacctatgt caatgctatc aacagtgtgg gcaatggttt gtatatcgat acagaacaag
    16381 aagcagtagt catcaaacca aaagaagggt tcggcggcat tggcggagag tatatcaagc
    16441 cgactgcttt ggcgaatgtt cgcgcttttt atacacgttt gaaaccagaa atccaaatca
    16501 ttggtacagg tgggattcgg acaggacaag atgcatttga acatctgcta tgtggcgcaa
    16561 gcatgttaca gattggtaca gagcttcata aagaagggcc ggaaattttt tctagaatca
    16621 taaaagaatt aacgcagatt atgtcagaaa aaggatatac gtcaattgac gaatttaaag
    16681 gcaaattacg caccatttca tagcaaagag acgaaggtca tgattgatct tcgtcttttt
    16741 ttataaaaaa cactcgtctg ttcattcctg tgcaagcgta ctcattgtat gttagacgaa
    16801 cttgtgggaa aataacagag gcaaaaagga ggataatatg aatgatgcaa cagaattagc
    16861 aaaagagctt aaagaaaaag aatttagttt tcaagaacta gttacggata tacagaaaaa
    16921 aataaagaag caaaatcatg aattgaatgc gtttgtcgcg cttgaaccat tcgagagtaa
    16981 ttcccacgag ctattgattc cccagtcaga aaaagggcca ttggctggta tcccatttcc
    17041 tttaaaaatg ctcggtcaag aaaaaaaggg atggctagct acttcaggat ctcgtttatt
    17101 tgaaacacac cgagcttctc atacatctaa ttatgtgcgg caagcagaag cgataggtct
    17161 agttcctttt ggacaaacca atgcgccaga gtttggtttc aaaaatatta cagacccagt
    17221 catctatggc ccagcaagaa acccttggaa ccttgaatgt acaccgggcg gatcaagtgg
    17281 aggagctgct gctgcagttt catcaggaat cgttccttta gctggtgcta gtgatggcgg
    17341 tggttctatt agaatacccg cttcgttttg cggattgatt gggctgaaac cttcgcgagg
    17401 gacgatgcca gttggtccat atgcttggag aggatggcaa ggagctgcta ttgatttcgg
    17461 cttgacagtt tctatgagag acacggaggc tttattttat gggatgagaa gtatccattc
    17521 cggtgcgcca tatcaagtat cgccagttga gtggcaaaca catccaagaa aaaaacggtt
    17581 gaagatagct ttttgtgttg attcaccgat ccactcacag attagtgaag aggcagtact
    17641 tgctgtaaaa aaagctgtag atttccttgg aaaagaaggg catgatttga cagagattcc
    17701 ttacccacta gatggtcgta aactgatcac gtcttattat cagatgaatg gcgcagaaac
    17761 agcagcaatg atccgctcga ttgaaacagg catccagcga gctgtcagaa aagaagaact
    17821 tgaacccatt tcttggactt tgttccaata tggtcagaag ctctctgccg ctacttacat
    17881 cgattctctg catgtatggg atgaagcagc aattgtcatg gaaaacctac atcaagaata
    17941 cgatctattc ctttcaccaa cgactgcatt taccgcccct aaaatcagcg aagatttgca
    18001 aagtgatgcg ataagagcac agatggaaca catcagtgat tgttctgaag tagaaggttt
    18061 agacgttgtt tcttccatgt ttgaggagag cttgaagatc acaccttata cacagttggc
    18121 taatctgact ggacaaccag caatcagctt gcctactcat ttgacaaaag aaaacatgcc
    18181 tctaggaatc caatttatgg ctgccagagg aagagaagat ttgctatttc aaatcggcta
    18241 tctatttgaa gcaaatcatc agttccattt accaaatcca tggaaatagc agaaacaagg
    18301 agaagaagaa tgaagaaaaa aagattgttt gctctaataa ctagtgcctt ttttatttta
    18361 agcgcttgcg gtacagctgc cgctaatcag gaagataaca gctggagtaa tgtagaaaaa
    18421 aagaaagaat tagtagtagc gacttctggc acactgtttc ccgcatctta ttataatgat
    18481 caaaatgaat tagttggtta tgatgtagat ttggcaaaag aggtggctaa acggttaaat
    18541 gtcaaaatct cctttaaaga atacaacgtg gatggacaaa tcacttctgt ttcaaaaaga
    18601 gaatcagatt ttgctgcgaa cgattttggt atcacaaaag aaagagaaaa aaaattctcc
    18661 ctttcagaga ctttcaaata ttcatttgac agtatgatcg tacgaaaaaa agatgattca
    18721 ggaatccact cacttgaaga tcttaaaggg aaaaaagcag ctggcgaacc caatactagc
    18781 tatatgcgtt tagcggaaaa acacggagct aaattagtca catatgacaa tgccacgaat
    18841 gatcagtatt taagcgatgt agcaaatggt cgaacagatg ttattctaaa tgattattat
    18901 ctgcagaaaa tggccgtatc tgctttacca gatatccctg taaaaatact ggagaacgtt
    18961 tatttcaatg aaaacgaaag tggtttttta ttgaaagaag gaaatgatgc tctgaaaaag
    19021 aaaatcgatg gcgtattaaa agagatgaaa gaagatggga cgacaaagaa aatatctgaa
    19081 aaatattttc aaactgatgt ttcagtcaaa ccgaaagaaa cgatggctga gtcggtgagt
    19141 gagtgatgta ctttcctcta attgattttt ccctcatgtg gacttcactt cctttcgtac
    19201 tgcaaggctt ggtatacaca ttagggattg gcttcgtgtc gtttctttta ggaaatttgg
    19261 tagggttgct tttgacagtt ttaggtcttt tggattggct gcctctgaat gtatttattc
    19321 gtttttattt atcgttcttt agaggcattc ccgcactagt cctgctgttt ctgttatatt
    19381 tcgggttacc ttatcaatta agtgccttaa cggcttcagt catctgcttt acgattacca
    19441 gcagtgcatt tattggtgaa atctatcgag gatcactagc aggcgtttct tcaggtcagt
    19501 gggacgctgg tttagcttct ggtttttctt tctttggggt attgaaatat atcgttttgc
    19561 cgcaagcttt tcgaatctca gtaccggcac tcagtaacgt agctatggat ctagtgaaag
    19621 gtacttcgtt agcagcaaca atcacagtgc cagaaatatt tcaaaaagca aagatcatag
    19681 gcggtcggac attcgattat ttttctctct atattttagt tgcactgatt tattgggtca
    19741 tttgtatcgg gatcgaaaaa gtgcaacagt atttagaaaa acgttctatc catcagtcaa
    19801 tctgaaaaat agaaatggtg ctagcgtggc tggcaccatt tctatttttt gtttcttgta
    19861 tattctgcct agtattttaa aaccatttca tgtaaaatgt aaatcgaaaa tatgttcgga
    19921 ggtagaaaac atgaagaccc cgctaaccat cgaaatagaa tcctcgttat accaatattg
    19981 catcgagcaa ggcggcttgg ttgtagaaga agtcacgatg cctgatgacc aaggaattgt
    20041 agatacgctt agctgcttga caaaatttga tggaagccga gaatggcgat gctatgagct
    20101 gaaagtgaca aaagcagatt ttcgctctac agccaaactg tcatttgttg gacattataa
    20161 ttattttgtt ttaccaagta aactatatga agaagtaaaa actgaaatcc ctacaggaat
    20221 aggtgtttta gtgtatcgtc cgtacacggt tgaagaggag atgcctgcct ctggtacatt
    20281 tctgattgcg aaaaaagcag caaagaaaga gcttgctgta ccggaagaag ctttgacaaa
    20341 ccgcttcatg gcttctttat tcagggaagt aagaaaagca aagcaaatgg agcgaggcgt
    20401 aaaatatttt ccaaaagatc aattgtacaa agaattgaaa agacgttcag aaaatcaaga
    20461 tccattttct aacgaacgat attatgaacg gtttttagag gaaatagcta gtcaggcaat
    20521 caatgagttg caagaagaag ttatcgcgct tcagcatgat tatgaatatt tgaggcaaca
    20581 acagcagatc cgtcggttgc ctacagagcc attggagtga aaaatatgta ctatccttat
    20641 ttaagaggaa aacaatttga cctattagca ttaaaagaag cactgtcgcg aggattgctc
    20701 tccaataaaa tccaaccagt gatcgaacca gtacgtgatt ccgctacgct taaaaatgtg
    20761 atcgaattat ttcaaaaaaa gcaccatcca atcgctgtga tccaaaatcc ccaagtagga
    20821 caattcaaat tattcgatca gcatgtgcac agttggacag tcaaagaaaa tagctctgtc
    20881 gtccctgcac agatcttaac gccagaaaat ctcagtgaag tactggattc acctccagcg
    20941 tttcttgttt tcgatggaca gcactaccca aaagatacag aggtgtggaa acagttggca
    21001 ggagttgatt cgaaattttt gataccagat actagtcgct ttcgcatctg gctgcccgaa
    21061 aacaaaattg tgatccgtga ctcttttcaa acgagaaagc atgttgaaag ttatgcagat
    21121 aaaacagatg acttttttag tgatgactat ctttttttcc acgcagacgg atatattgga
    21181 ttttctgatt tcacgatcga aggtagccgt tatttcgata aagggttccc tagccgagcg
    21241 cttgctatcc atctaacgta tattgatgct tacggcaata tacgcgtgaa acattttgtc
    21301 tctgacagta acgactctgc taaagaccaa gcattgaagt ttcttgaagc aggagataaa
    21361 atgaaaaaat ggatcatgcg tcaccatcat caactcttga ttacttcagg aatgattgaa
    21421 ttattggctc tttaccagca acaaaaattc cctggactgg gagtgttgaa aaagtggtca
    21481 cttatgcatc atttggaact tattagtcac ctgctagatc atccaaaaga ttggcttaaa
    21541 tattattcaa aagttcagga actatatgaa gtgatccaat gattagataa tgtaaatgaa
    21601 aaaggaatag aaaagaggaa actggatgta tattcggcaa acaaggaaag aagaagtaga
    21661 agaagtggta gaaatcatta atgccgcagc ggatttcatt gcttcgcaag gctctcctca
    21721 atggcaaaac gggcagaaac caacaaaaga aacgattttg aacgatattg aaagaaaaga
    21781 aagctatgta ttaatagtgg aagatcaaat tgctggaaca gctgcattag tctcaggcgt
    21841 ggatcccgtt tacacaaaaa tagatggtag ttggaaagaa tcaactggtc cttatttatc
    21901 gattcatcgt gtcgctttag cagaaagtac tcgaggaaaa aaactagcaa aaccgttctt
    21961 agaacatttg ttgacgattg cagccagcaa aaatatccaa gatatccgta tcgatactta
    22021 tccagctaat gaaccgatgg aaaagaccat ctattctgct ggattcactt atcaagggat
    22081 gattgaattt ccttttgaac acggcgaaag aaaagcatat caaataatca tcaattgact
    22141 ataaaatcat ctgagcaaag ataaagacat taacactact gaaaaaaaca atcatatgat
    22201 agccaagagg ttgtaacaga agtggccagc ttcaaaaaac aagaaagaat ttccgaaaat
    22261 gcttctcaaa tttttgtgga attttagcgt attttacgaa atagctgctt tctgaaactc
    22321 ccttcatcga gaggtcgtga catagctttt gtcacgatct ctcggcttat cctacgagta
    22381 ttattcgata catttatatc aataatcctt tttttatttt atctgcagct tcttggaacg
    22441 ctccatcgtt tgacacgact aaaagtgagg ggatagcttt caaacgtttc aactgtgcta
    22501 aatcttctac ataaaccgcc agtctggctg aaatctgttc agatgaatct ccacgttttt
    22561 tcaggcgcga ttgcaatgtt tctttagaga tcgtaataaa gataggacgg actaccgtcc
    22621 cgaaatactc atataaatgc caaaaaccat ttgctgtcaa aacggcgtaa caatttccta
    22681 ctgtcagttt ctttttaatt tctgctttac tggaaccata tttatgttga gcatattggt
    22741 cccactctgc aaactcattt cccttgatca tctgattgaa tgtattgtca gaaacaaaat
    22801 aataatcctc ttgatctttt tccccaggtc ttggtgatcg attcgtgtaa gtaatgatct
    22861 tttgttccgg ctgaaaaata gcttctgcga gtgaagtttt tccagaacca gaaggaccga
    22921 taaatacata gcaataattc attgtcattt ctcctttgat gattgaacaa gtgaaaaagc
    22981 tttggaaaat atttccaaag cttttaaaag taactttgct tttttgtatt ttataccagc
    23041 aagccagtca caatagcact taaaaagctg actaaagtcg ctgttagcaa aattttcaat
    23101 ccgtgttttg cgacaagatt tcctttttct tcatttaatc ccttcatcgc accagaaatg
    23161 atcccgatag aagagaagtt ggcaaatgaa acgaggaaga cagatataat tgctgttgta
    23221 cgctcagtaa aatggaaatt accatttgct aattctgtca tagcaacaaa ttcatttgta
    23281 accagtttag tcgccatgat actaccggca tccactgctt ctttccatgg gattccgctg
    23341 atgaaggcaa gaggggcaaa gatgtaacct aggatctctt ggaaagtgat gccgaatatc
    23401 ccgtggaaga tagcattgat catggcaatc aaagcaacaa aaccgataag catagcagca
    23461 accgtgatcg ccacatggaa accatcaaga atgtattctc ccaacatttg gaaaaatgtc
    23521 tgttctttgt tttcttcaat gatcagctca tcttcttttt cttctaatac atagggattt
    23581 acaattgaag ccagaatata accgccaaat aagttcaaaa caagggcagt gatcacatat
    23641 ttagaatcga tcagtgccat ataagatccg acgatcgaca tagaaactgt agacatagcc
    23701 gatacactca tggtgaacaa acgtttctca gataggaagg gtaattcctt ttttatggaa
    23761 ataaaaactt ccgattgtcc taaaatagca gaagctactc cattataaga ttccaatttg
    23821 cccatcccgt tgattttact taatcctaga ccaacagctt tcataaataa tggaagaatc
    23881 ttgatatagc gtagaatacc gataatagca gaaataaata caattggcat caatacggaa
    23941 agaaagaaag gtgcacttcc tttatttgct acaccggcaa aaacaaagtc aacaccttgc
    24001 ccagcaaaag caagaagatg atcaaacatt tttgccaata cagaaacaac cgctgtacca
    24061 aaagttgtac gtaataatac gaaaccaaga acaagctgta aaacgaacat cacaattagt
    24121 ggtttcaatt tgattgcttt tttgttactg ctgatcaaaa aagcaagccc taatgtgaca
    24181 aataaaccaa taatacctaa taaataactc aaataatcac tcctattcca aattccgttt
    24241 tattttacct gttttgcaaa taaaatacta atctttagtg aaattttcat tactttttta
    24301 gagtgaaacg cattcatttt ccattagaaa ataaagcgaa caaaataaaa ggtttaaaaa
    24361 gtgtaacgtc ttagtaaagt ctataaaaaa acgaaactat cgattaagct aatagtttcg
    24421 ttttcaacat ttataagtaa actttttcta ttggtaatat agattttcgg aagggtagac
    24481 aggtgcgcag gtaatatcga ttcctagttt tttcaatgtt tgttcatcat ttttattgac
    24541 catcacagta gagtgggctt gtgctccctc aagttcagct agtttatcat aagcaacttg
    24601 agcgattgga ttcgttactg cactgattga taaagcgatc aagacttcat tgatgcttag
    24661 tgcatccaaa gaggaatgaa gtgtctttga tttcaatcct tgtattgttt caagaactaa
    24721 tggtgacaat aaaggaatgt catctgcgat atgggctaaa tgttttactg catttaagat
    24781 aactgccgct gacgcatcca tcaatgaact tgtacgcccg gtaatgatga cttcatctgg
    24841 taattcgatt gcaatcacag cagaaggatc ttttgtagga ctttgcgctt gaatcttatc
    24901 tgcatagtca tgggcaggga ctaccacgtt tcggtcttca ggacgtaaac cgacttcttc
    24961 cataatcagt ttgattcgat taactgcttc ttcgtcgatc aatccttttt tgaagtcgca
    25021 ttctgtttgg aaataacgac ggatgatttc ttgtttagag gcttcttgga caacggtatc
    25081 atccacgatc ccaaatccta cacgattcac acccatgtca gtaggagatt gataaacaga
    25141 ttctttacca gtaatttttt caataatacg tttgattaca ggaaatgtct caacatcccg
    25201 attatagttc acagctactt tattgtaggc atcaaagtgg aaggaatcga tcatattgac
    25261 atcttttaga tcgactgtgg ctgcttcata agcaatgttc agcggatgtt tcaacggaac
    25321 attccatact gggaaagttt cgaacttgga gtaaccagct gcatgtcctt tttggctttc
    25381 atgatacagt tggttcaagc aagtagcgag ctttccactt cctgggccag gagctgtcac
    25441 tacaacgatt ggtttagttg tttcaatata ctcatttttt ccaaaaccat cttctgagac
    25501 gattttttct acgttgactg gatagtcttc gatttctgag tgtttataga ccttgatgtt
    25561 tcgtctttct agtttattga taaagacttt cgtggcaggc tgtccactat agcgagtgat
    25621 aacgacactg ttgattaata agccataacc acgtaattca tcgattaacc gcaagatatc
    25681 catatcataa gtaatcccat aatcaccacg gatcttatta cgttcaatat ctccagcata
    25741 gacgcaaatc agtatttcag cttgatcttt caatttttgc agcaatttga ttttcgcatc
    25801 ttcttcaaat cctggaagta cacgtttcgc atgcttgtcg tcaactaact tcccaccaaa
    25861 ttctaaatat aatttgtcat agtggttcac tcgttccaaa atatacgctg actgctcttc
    25921 aatatatttt tctgaatcaa aaccaatttt tttcactagg ttccctcctt aagtactaaa
    25981 gcattttttc atttttttga ggattcgtca actggaagag cgaaattcct caaaaaaaca
    26041 aagaaaatgg tttaaaccaa cttgtctaga tagttattca ttggtatgat agtttttgat
    26101 aaggaaggtg ctacatgaaa aaaagacaga aaaagaaaaa cgcatataaa cactatatcc
    26161 gttcgatttt taccggttat gaaagaatgc ttgaagatcc cgaattggaa caattgacgt
    26221 ttacttatct aaacgaagaa acgcagctaa ctcgtgatga gcatcagcgc attcatttca
    26281 caacaagaga tctgcctagt aaataaaaaa taagataaag gtcatcggat tcgattctgt
    26341 cctatcagat ggaaagacta gttgatcgaa aaaaaggctg taccaaattt tggtgcagcc
    26401 tgttttatgg agcattgccc gctctttttt ataacaattt tttacagaaa atggtactat
    26461 tgaagtatta ataagtgaaa aacagatgag taagaggagg caagtagtat gaaagagcca
    26521 gatacaaatg caaattatga gccagacgaa ctagaggaga cgaacgcgga tcaggataca
    26581 ggacaagaat cgtcttcttt ttacgatatc aaagaaaaag caagcatgaa tctttcccaa
    26641 ttattagaag acttacaggc ttttgaaaaa gctgtccgcg aagaagatat ccctgagatc
    26701 taccgtttat acaatggccg attgaatgaa gaattaaaaa gaagctcaaa tgaaaatcac
    26761 gagatcgatc aattgctgat gcgtaagatc catgatcgtt ttttacagga atttcctttt
    26821 atggaacaag tagaaaacat ctcgccaacg atgagctatt acaaaatcgg cacttattac
    26881 catgatcggc ccacggtcgg tattgatgca agtctgccag aaatttttgt tttgcctaag
    26941 atcgatgaag agtgggagaa atattcccaa ccggagtcaa cggactatga caaaaaaatc
    27001 aatgagctag acgcaaaggt gatcactgct cagacagaaa ttgaacgttt agatgaacaa
    27061 ataaaagaaa tcaatcgaca aatgactgat ttgaacgaca ataaaggatt cttgaatcgt
    27121 aaaaaaatcg aggaagaaat tcaagaatta gagaagaaga agcaagtact atctaatgaa
    27181 aaattaggct ggcttcctta tattgagacg cctgaaacaa tccagcagca aaaagaagca
    27241 ttgaagcaag aagcaagagc agaccagctt cgtgcagcca tcgtagaaaa agaacaaagg
    27301 caaatcagac gctatttcgg tagcaaagag ggattcggtc aagcaatcca tgaattcttg
    27361 atgaattatc ttggcaatga gaatcctaat aatcaatcta atgaaggagg ttccgagtat
    27421 gaatgaacac gatgaagcag aatggacaaa aaatgaagaa caaacagaag atcatgaaga
    27481 aacgaacact tcattggaag aacaaacaag taatcctctg gatgacacag aagaaatccc
    27541 tatgctagag gaaacaaaaa tacatgaaaa agaaaaagta actccgacga atacgaatac
    27601 tgcagaaaac acccatgctt acgaaataac tgaaaatccc gggtatttag aaggaaaaga
    27661 gcaagatcat caagatatcg tcagtttgat tgaaacagcg gaagcagaat tagcggattt
    27721 acgtatgaga aaagatttga tcgaatcaga ttttccacaa ttattagaat catatgatcg
    27781 ttttatattg aatgaagaac caatctccac gatcggaaag acaagcctga tcgaatactt
    27841 cacgtatgaa ttactgaaac cgttgaatga tattggtctg gaacggtcaa attcagctta
    27901 tgacacatgg aaaacaagac atttttcgat caattatacg ttgaatggac aaaacgaatt
    27961 agtcttttcc tttgtattac cgaccatcga tcaacgatac caagtggaat cgatgagtct
    28021 cctaaacgta tcaccagaga caatggaaat caatgtccaa gatgaccggg tgctttcttt
    28081 gatccgacac tggtcagtgg atcgagtatt ctctgcaggg cagatcacga tattcaatca
    28141 caaattgaat caattattag cccatgcaag aacacttggt tttaccgtta atcagacatt
    28201 actagacaat acgaagccac ttcgtttgaa tcttcagagc gaatttgaat tgacgaatga
    28261 agtattggat gatattttta tcgtggcaat gaaaaatcca tcctacgata tggaaaagat
    28321 caacgaaact acttatcaag tacgattaga taaaggacag tctttaacga taacaacaaa
    28381 cgaaaaagat caaacagtct tgtcgatctc atctggagac tacccacgat ctgtcattga
    28441 tttctttatc aattacgaat tcttggtccc attaatggtg agaaagtcct gattggataa
    28501 gttggattac cagatgtcat tcagataatt ctgttccaaa ggacttgcgg cagttatcca
    28561 gaataattgt cacaagtctt ttctgtatgt actaaatgga cgtgaataac ttgctgatga
    28621 aggagggatt tcattaggaa tgtccacaaa taaaatagca cagcttagct tattgtctgc
    28681 tgcttgtgta gcaggtagga tcgcttttca atttattccg aatttccagc caatgactgc
    28741 tattttttta tttatagtac tttacttaag cttaaaagat gcgttaattg tcatgagtct
    28801 ttctattgcg atcagcagtt tttattttgg tgttggacca tgggtcatcg gccaatggat
    28861 cagctatact gttgttctga gtttgttttc aatcgtctgc ttgagaaaaa cagtgcaaag
    28921 gaatctatgg ttaaagggag tctgtttttt tctggcgggc atggtttacg gaataggtat
    28981 gaccgttttt gatacgctgt tatatcgttt gcctcaacct tggatctatt accttcaagg
    29041 ggtgtcgttt gatttgatgc acagtatagg caatgttgtg ttctttcttg tttttctgcc
    29101 agtcgtcaaa cgtttttaca atcattcagg aggaaaaaat gaaaaaaata atttatagtt
    29161 tgcttgcaat gagtgtcagt atactcattt tgacaagttg cagtacaacc tatacacaat
    29221 cggcttccaa ccaaaaggag gaagtaaaaa catcgcaaaa agcaacaatc acgttacaag
    29281 aaaatggtca aaacttttcg gaaaaagaag tggtcttcaa aaaaggcgat gatttactga
    29341 gtattttgaa acgaaatttt gaagtcaaag aagataacgg cttcatcact tcgcttgaag
    29401 ggcactcaca ggatgagaaa aatcaactct attggatgtt tactgtggac gggaaaagtg
    29461 ctactactgg tgccaaagag atcaaattga atgatggaca atcggtcatt ttcaatttgt
    29521 ctaaactata agtttcataa aaaactgtta aagggcgaat attgccataa ttcagtgagt
    29581 tcagttgatg aaagaaggaa aataacatgg aaaattttaa aaaaagcgga atgttttccg
    29641 taattgctgc tctaggggct aatattctag ttgctatcag caaatttgtc ggctatgcaa
    29701 tcagtggcag tgccgccatg ctaaacgaaa gcatccacag tatcgttgat tgcagcaatc
    29761 agattttgct gttattcggt gataaacaag ccaataaagg acagagcgag ttgcatcaat
    29821 ttggtgaagg acgagcaaaa tactttttca gtacaatcgt cgcaatgatg cttttcttcg
    29881 gcggtggggc acttggggtg atggaagctt ttgaaaagtt gacgcatcca tcccatgaag
    29941 tgggtaatcc gatcattgtt atagcaatac tgttatttgg tttggtaatc gaaggaagtt
    30001 cgttacgcgt ggcaatgaaa gaaatcaaag aattgaatac tgaaaaactt tccacgatgc
    30061 gctttttgcg cgaaagtcga cacagtgaaa tactgattat ttttacggaa gacttgtgtg
    30121 ctgtaatcgg tttggtcttg gctttagcag gaacaatatt gacttatgca accgggattg
    30181 ctgcatttga tgcgatcagc ggattgctga tcggtttctt gctgatggga gccgccattt
    30241 tcctagcaaa agaattttat agtctgatca tcggtgaaag cgtgacagca agcgatttat
    30301 caaaaatcaa gttagctttt gaacgtcctg agatcagtcg gctgatcgat ataaaaacag
    30361 ttcatttaag tccaacggag attttagttg cagcaaaagc agatatcgtt ggtaacaaag
    30421 agaatgaagc ttactcggtc atcaatgata ttgaaaaaaa tatgcgtcag tctcttcctg
    30481 acaagaagat gtatatatac attgaaacag ataaatatga cccaaattat tctcgtaaat
    30541 aaaacgttta ttcatgaatt gaagcaaaaa tgagaaaaat ataatcttgt ttttaaataa
    30601 aacggctaca atttagcgaa tttatgttac aatgagtccg ctgtttattt gttgtaatta
    30661 aaggagatat tttaatgaac aaaaagaaaa gtgcgccatg gcttcaagct ttgcatgcag
    30721 tgatgccact ttgtataagc tatataccag taggattagc ttgcggagta ttgttgcaaa
    30781 aagttggatt tgatcctctc ttatcaggac tgttatcgat tctggtcttt tccggtggcg
    30841 cgcagttttt agttgcatct atgcttacga cgcaagcatc atttgcaacg acattattga
    30901 tggttttctt tttagaatta cgctatacat tattaggagc aagtcttgcc ggttttatga
    30961 aaaaagaaaa gcggacgttt ttggctgtct tttctcaatc actgaatgat gaaaactatg
    31021 cggtgaacta cttaaagttt tcaactgacc cttcctggaa taaaagaaag gctttatatg
    31081 tcaattggtt ctcaatgact gcatgggccg gtagcaatat gatcggtaat tttttcggct
    31141 cggtgattcg agtagatgct gaccttgtcc attttgcttt gacggccatg ttcattttca
    31201 tgtttatcat gcagatgaaa agcgcactac tgatctttac aggtttattc tcaggcgtat
    31261 taggggtcgt attcatggta ttattccaaa atactttcgg attgattgca gcaacagtca
    31321 ttgcttcatt tgccggattt atgctggaga aggcattcaa aaaagaaaaa gctaagaaac
    31381 taagagaccg cggtaaagat gtcaatgagc cgctcttcaa cttcccggaa caggaggcca
    31441 atcaccatga ctaaactata tttgctactt ttagttgctt gtctgttcat cgtggcatat
    31501 atcccgcgct tgttcccgat gctttatttt actcatcgaa aagtgccatc ctggttcagt
    31561 gactggatga aatatgtacc ggtggcatta tttgcggcgt tagcttttaa agatgttttc
    31621 attactcatg aacatctgga tattgcttgg aatatcaaaa tagctgcaat gattctagta
    31681 gcaggcgtgg cttacaaaac acgttcgatg gcgttgtcag ttttgacagg acttgcgtct
    31741 gtctttttgc tgtctatgct ttaaactgtt ttattttatt aaaaacagag attgcgacat
    31801 aagttgttca aactgatcta tccgaactgc atttgcaaca gtcaattctg gatgcaagtt
    31861 tattcgtagg gataaaaaag attagtgttg gcttatgatg caagctcttt tttattttag
    31921 gaattagaga gggatttgtc cttctatgat tttttgctat aatagggaag atgtttattt
    31981 tatgaaagaa tagttgaggg aatttaaatg aataaaaaat tgatgcaagg aacattttgg
    32041 ctaacctttg ctaatcttct atgtaaagtt ttaggggtag tctatttgat tccctggcta
    32101 agtatgatgg ggaacaatca agatggtatg cttgctacga cattgtataa tgttggctat
    32161 cttccttatg gattgttcct gatgcttggt acagtcggat ttccaaatgc gattgcaaaa
    32221 aaagtagctg tagccacaaa agaaggagat aacgctgctt gtcggctgat ttttagaagt
    32281 acgatcaata tcatgtttgt catcggtatc gcctctgctg cactgatgta tttatttgct
    32341 cctttactag ccggaatcag tccgattgct aacgttaata atgggatact agctatcaga
    32401 agtttatgcc catctttgat tgctatccca attcttagtg caatgagagg atatttccaa
    32461 ggaaaaaatg atctgcggcc ttatggaact tctttgatta tcgaacaggc tgtgcgagtg
    32521 atcgttatct tggctggtac ttattacttg cgcgtattga ctgacggaac catattagaa
    32581 gctgtattga tcagtacagt cgcttctttc ttcggtgggt tagctgcgat tatccatatg
    32641 tatatcgtcg gacgcagaaa agacttcttc gaacttaaag attttttgat ttccagccgt
    32701 tatttcgaaa gagaaaaccg atctgcctct gtctctatca ttcgggaaac actaccgttt
    32761 atttttgtcg gctcagtcat tactatcgtt caaatgatcg accaagtaac gatgaaacca
    32821 ctgcttcact ttttccgtcc agagatcgca gatcagcaac tggaattctt attcagccgt
    32881 gcttctgtca atccaaataa attgacattg atcctgatct ccatggtagg aacagtagct
    32941 ataagcagct tgccaatatt aagcacgatg aagaaaaaag atcggataca aatcgaaaaa
    33001 acagtaggag atagtttttc gattgcgtta ttgattcttc ttccttcatt gactggaatg
    33061 tctttattag ctggaccact atacacattg ttttttggct atgatcctga aagtgtcgga
    33121 tatttccaaa tggctttgct agcttctttg tttttctctt tattcacgat cctatctacg
    33181 atgcttcaat ctttgaatca ccatcgtttt gcgatccgat taactgtaga agcaattatc
    33241 ctgaaagtca tcttccaagt aatcggatta ggattagttg gcggatacgg gatgagctta
    33301 tcaaatggct tagcattcgg tattgtcttt gttcgcggct atcactttat gtgcaaagaa
    33361 taccgaatag cacctttagc aaagatcagc aattttttct taaaaacttt ccgctccacc
    33421 ctgattatgc ttgcagtatg ttttgccgtt ttctttttgc tgaatcagcg attgtcaatg
    33481 gaatcaaaaa gctatgcaat gatttattgt gtggctgtag gaagtattgg cggcttagta
    33541 tttttatttt ctcaattcgg aaaaaatggg tttcgaatgt tgaaaaatgt taaacatcat
    33601 agcagaagca aagaataggt taactaatcg ttttttgctg tcacttgaaa aacggcaact
    33661 cgtatgatta cgcttgtcgt ttttctattt tccaatttta gtttcatatc taatcttact
    33721 tatgatatag ttataaggtc tggaaaaatt ctttgaaacg aggaaattaa acacatgaaa
    33781 cttgcagtag ttacagatag ttcggcatat ctgccggaac gtatcaagaa ccatcccgac
    33841 ttattcgtta ttccaatccc tttgattatg gatgggaaaa tttataacga aggaatcgat
    33901 atcgaagcgg atgaatatta tggactttta aaaaacagta aagattttcc tactacttca
    33961 caacctgtcg taggggaagt tttgggttta tatgaggaat tgaaagagaa agggtatgac
    34021 acgattttaa gtatccatct ttcttcaggg atttctggct ttgtcaacac attatttgcg
    34081 atgaaagatg acatcagcgg agtaacggtc attccttatg actctaagat cactagtatg
    34141 ccgatgggac acatggtaga agctgcctta gacttaaatg atgaaggtca gtcccttgat
    34201 gaaatacttg cacatatcga tcgaatccga gataatacct atgcttatct gattgtagat
    34261 gatttgaaca atttagtacg aggaggacgt ttgacaaatg gtgcagcgct gattggcagc
    34321 ttattaaaaa tcaaaccgat cctgacattt tctgaaggga aaattgtttt attcgaaaaa
    34381 atccgttcaa gtaaaaaagc atttgctcga gctgaagaaa ttattggtag aagaaataac
    34441 gaaatacaac cgccagtcaa actttacgtg atacatgcaa ataatttaga agtagcgatt
    34501 gcggagaaag agaaattgca gaaaaaatat ccaaatgcag aaatcgaaat tggtcatttc
    34561 ggaccagtca ttggtacaca tttaggtgaa aaagccatcg gcattgccat ttcagcgcaa
    34621 taattccttt tattcaaaaa acataccaaa aatat
//
LOCUS       DAYNVV010000026        31334 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.026, whole genome shotgun sequence.
ACCESSION   DAYNVV010000026 DAYNVV010000000
VERSION     DAYNVV010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.026"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            1..369
                     /locus_tag="ACGXWR_001413"
     CDS             1..369
                     /locus_tag="ACGXWR_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HFK0802994.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            549..1490
                     /locus_tag="ACGXWR_001414"
     CDS             549..1490
                     /locus_tag="ACGXWR_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HFK0802995.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1559..2290
                     /locus_tag="ACGXWR_001415"
     CDS             1559..2290
                     /locus_tag="ACGXWR_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFK0802996.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2434..4614
                     /locus_tag="ACGXWR_001416"
     CDS             2434..4614
                     /locus_tag="ACGXWR_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HFK0802997.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4634..5116
                     /locus_tag="ACGXWR_001417"
     CDS             4634..5116
                     /locus_tag="ACGXWR_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HFK0802998.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            5132..5893
                     /locus_tag="ACGXWR_001418"
     CDS             5132..5893
                     /locus_tag="ACGXWR_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFK0802999.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            6024..7358
                     /gene="murC"
                     /locus_tag="ACGXWR_001419"
     CDS             6024..7358
                     /gene="murC"
                     /locus_tag="ACGXWR_001419"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HFK0803000.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            7665..8150
                     /locus_tag="ACGXWR_001420"
     CDS             7665..8150
                     /locus_tag="ACGXWR_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="HFK0803001.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            8143..8826
                     /locus_tag="ACGXWR_001421"
     CDS             8143..8826
                     /locus_tag="ACGXWR_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HFK0803002.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            8952..11597
                     /gene="polA"
                     /locus_tag="ACGXWR_001422"
     CDS             8952..11597
                     /gene="polA"
                     /locus_tag="ACGXWR_001422"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HFK0803003.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            11642..12478
                     /gene="mutM"
                     /locus_tag="ACGXWR_001423"
     CDS             11642..12478
                     /gene="mutM"
                     /locus_tag="ACGXWR_001423"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HFK0803004.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12442..13071
                     /gene="coaE"
                     /locus_tag="ACGXWR_001424"
     CDS             12442..13071
                     /gene="coaE"
                     /locus_tag="ACGXWR_001424"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HFK0803005.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            13123..13455
                     /locus_tag="ACGXWR_001425"
     CDS             13123..13455
                     /locus_tag="ACGXWR_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFK0803006.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            13767..14258
                     /gene="nrdR"
                     /locus_tag="ACGXWR_001426"
     CDS             13767..14258
                     /gene="nrdR"
                     /locus_tag="ACGXWR_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HFK0803007.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            14281..15654
                     /locus_tag="ACGXWR_001427"
     CDS             14281..15654
                     /locus_tag="ACGXWR_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFK0803008.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            15654..16580
                     /gene="dnaI"
                     /locus_tag="ACGXWR_001428"
     CDS             15654..16580
                     /gene="dnaI"
                     /locus_tag="ACGXWR_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HFK0803009.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            16709..17149
                     /locus_tag="ACGXWR_001429"
     CDS             16709..17149
                     /locus_tag="ACGXWR_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFK0803010.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            17293..17994
                     /locus_tag="ACGXWR_001430"
     CDS             17293..17994
                     /locus_tag="ACGXWR_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HFK0803011.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            17991..19112
                     /locus_tag="ACGXWR_001431"
     CDS             17991..19112
                     /locus_tag="ACGXWR_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFK0803012.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            19127..20359
                     /gene="pepT"
                     /locus_tag="ACGXWR_001432"
     CDS             19127..20359
                     /gene="pepT"
                     /locus_tag="ACGXWR_001432"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HFK0803013.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKVFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            20491..21399
                     /locus_tag="ACGXWR_001433"
     CDS             20491..21399
                     /locus_tag="ACGXWR_001433"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFK0803014.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            21434..21706
                     /locus_tag="ACGXWR_001434"
     CDS             21434..21706
                     /locus_tag="ACGXWR_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HFK0803015.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            21717..22763
                     /locus_tag="ACGXWR_001435"
     CDS             21717..22763
                     /locus_tag="ACGXWR_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HFK0803016.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            23014..25623
                     /gene="clpB"
                     /locus_tag="ACGXWR_001436"
     CDS             23014..25623
                     /gene="clpB"
                     /locus_tag="ACGXWR_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HFK0803017.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(25774..26460)
                     /locus_tag="ACGXWR_001437"
     CDS             complement(25774..26460)
                     /locus_tag="ACGXWR_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803018.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(26438..26932)
                     /locus_tag="ACGXWR_001438"
     CDS             complement(26438..26932)
                     /locus_tag="ACGXWR_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFK0803019.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(26952..28172)
                     /locus_tag="ACGXWR_001439"
     CDS             complement(26952..28172)
                     /locus_tag="ACGXWR_001439"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFK0803020.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            28319..30154
                     /gene="lepA"
                     /locus_tag="ACGXWR_001440"
     CDS             28319..30154
                     /gene="lepA"
                     /locus_tag="ACGXWR_001440"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HFK0803021.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(30248..>31334)
                     /locus_tag="ACGXWR_001441"
     CDS             complement(30248..>31334)
                     /locus_tag="ACGXWR_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFK0803022.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT        10430 a         5601 c         6715 g         8588 t
ORIGIN      
        1 atgtttacga atgaaataaa aatcatgctt tatgtggacg atgtagaaaa aaatgcaacg
       61 ttttggagag cagttggctt tgcggaaaaa gatcgtcaag aaatggatgg gacgcttata
      121 attgaagtag gagttgagga cagtcaaacc tcatttctgt tatatgatcg agcatttgtt
      181 gagtcccatt cacctggcac agctactagt gccccatctt tgatgtttta cagtaaagat
      241 atctttggac tatataaaaa aatgcagacg caatcagtca cattaggtga tatggtacag
      301 cttggagaag aatatgtctt taactttgct gatcccgatg gcaactactt tgcggttaca
      361 ggtaaataat agaaataaag actttgtttt tctgtgcgaa acaggaaagc gaagtctttt
      421 taattcaaat aataatatta tgtaaacaaa aaactttcca tgcgtaatta tacacaagca
      481 aataaatcgt caaatgcgaa cgccttcttt atactgttta ggaacgaaaa gaaggaagga
      541 agaaatacat ggattatcaa gtactgcttt attacaatta tacaaaaatc gaagaaccag
      601 aggaatttgc caaaaatcat ttagcctttt gcaaatcttt ggatcttaaa ggtcgtattc
      661 tagtagctga agaaggaata aatggtactg tgtctggaac cgttgaaaac acgactgcct
      721 atatgaaagc aatgaaagct gatcctcgat ttgctgatac gatgttcaag atcgatccaa
      781 gcgaaggaca tgcctttaag aagatgtttg taagataccg tccagagctt gtaagtttaa
      841 agctagaaga ggacattgat ccaaaccaag tgacaggtgc ctatctttca ccgcaagaat
      901 ttaaagaagc tattttagat gaacagacag tggtgattga tgcacggaat gattatgaat
      961 atgacttggg acattttcga ggggctgtac gcccagatat acgcagtttt cgagagcttc
     1021 cagactggat ccgcgagcac aaagaagaat ttatggaaaa acgggtagtg acctactgta
     1081 ctggtggcat tcgttgcgag aagttttctg gttggcttgt ccgtgaagga ttcaaagatg
     1141 tcggacagct gcatggcggt attgctactt atggtaagga tcctgaagtc caaggagaat
     1201 tatgggacgg caagatgtat gtgtttgatg aacggatcgc tgtcgatatc aaccaagtag
     1261 ataaacaaat cgtcggtcgc gactggtttg acggaacacc atgtgaacga tatatcaatt
     1321 gtagcaatcc tgagtgcaat cgtcagattc ttgcttccat tgaaaatgaa gaaaaacatt
     1381 taggagcatg tagcatagag tgtgcgaaac atccgcgcaa tcgctatgtt caagaccatg
     1441 gaatctctcc agaagaagca gaactgcggt ttacagcttt aattaaatag aaaacaatag
     1501 ttttgattgt cgaccatttc caatatgcgc tatactagcg ttgaggatgg tgatccacat
     1561 gaaatcattg atttatgcta ttggggatgt ccatggcaaa catgagcttt ttgaaaaact
     1621 tattcactat tatgatccaa agatccatca gcttgtttta ttaggggatc tcaatgatcg
     1681 aggtcctcgt acaaaagaat gttttttatt aggaaagcaa ttagtcgaag aaacaggagc
     1741 catttacctc cggggaaacc atgaagaata ttttttgcaa tttctgcaat caccggagga
     1801 ctggtatgcg ccttatatga gaaatggtgg aaaagaaacg tttgaaagcc tgattcaccc
     1861 aggggcatcg gaggaatact ccccaactga aatctcgatg atgatccaat cgagatattc
     1921 agaactgatt aaatttttag tccagcgccc cttgtattat gaatgggaaa attatctttt
     1981 tgtccatgcc ggtgtggatt tgacaaagaa agactggcgt aagacaagtc taagagactt
     2041 tatttggata agggaaccat ttcatgaagg gaaaaacaat acaggtaaga caattgtatt
     2101 tggacatacg attacaccaa tgctccatgg agatatgcag acaacagacc tctggattca
     2161 ggatcataaa atcggaatgg acggtggggc tgtattcgga gggtcattgc atggggttgt
     2221 ttttgacaag gaaggtattc ttcaagatat tgaatatcag aacaacgaag gaccttggca
     2281 tggaatctga ctaatggaaa gaatgaagga gctgtgactt tgttgcggct ctttttattt
     2341 ttatagagaa tattgtttct ttcagtagtt taacccagga taaaaagtat gatagaataa
     2401 agaagcaatt tttagcagaa aagaggcatt ttaatgacgg aaaatttgaa ccagacgatc
     2461 attcagcttg tacaaaaaga actttcagac tatcgtccta agcagttgac tactgtactt
     2521 aatttgttaa atgaaggaaa cactgttcct tttatcgcgc gttaccgaaa agaaatgact
     2581 ggaagtcttg atgaagtcca gattcgtgaa atcgaagagc ggtatgccta tcttgaaaac
     2641 ttagaaaaac gtaaaactga agtgattcgg ctaatcgatg aacaagggaa actgactccc
     2701 gagttagaag cagaaatcac ccaagccgtg aaaatgcaac aagtggaaga tttgtatcgt
     2761 ccatacaaac aaaaacgacg gacaaaagca acgattgcta aagaaaaagg acttgaacca
     2821 ctcgcgaagt ggctgatgca gcttacagat ggagaggtgc aatctgaagc agaaaaatat
     2881 attgacaaag aaaaagaagt ctcttctgcc gaagaagcgt tgcacggtgc tcatgagatt
     2941 attgctgaac aagtcagcga taatgcaaaa tttcggactt ggattcggtc ttatacgtat
     3001 aacaaaggta tgtatgtcag caatgtcaag gatgagcaag cagatgaaaa aggcgtatat
     3061 gaaatgtatt atgactttgc agaacccgtc cataaaatgg tttctcatcg aatattagct
     3121 actaatcgtg gagaaaaaga agatattctg aaagtattct ttcaagtaga tgaagcagca
     3181 attttagctt acttggatcg ccaaatagtc aaaaatcctg cctctccttc ttcttcattc
     3241 gtcagagaag cctatcagga tagttataaa cgctttattc agccagcaat cgagcgagaa
     3301 ctgcgcaatg aattgactga aaaggcagat gagcaagcaa tcgctatttt cggcgaaaac
     3361 ctccgtaatc ttttgttgca accgccacta aaaggtaaag ttgtcctggg atttgatccg
     3421 gcttatcgta ctggatgtaa actagcagtc gtagatgcga cagggaaagt tttagcaatc
     3481 gaagttattt atcctcataa acctgcagcg caagcaaaaa gagaagctgc tggaccagct
     3541 tttatccaat taattaataa atatcaagta gatatggtag ctatcggaaa tggtacagcc
     3601 agtcgggaat ctgaactttt tgtggctgag cagttgaaat ccgccgacca taaaacctat
     3661 tacgctatcg tcaacgaagc aggcgcttct gtttactccg ctagcgaaat tgcacgaaaa
     3721 gaatttccgc atctacaagt tgaagaaaga agtgctgttt ctattgcccg tcgcctgcaa
     3781 gatcctttag ctgaattagt caaaatcgat cctaaagctg tcggagtagg ccagtaccaa
     3841 catgacgttt ctcaaaaacg tttggctgaa caattggatt ttgttgtgga aacagcggtt
     3901 aaccaagtag gtgtggatgt gaatacagca agcccgcagc tcttgcagca tatatcagga
     3961 ttgaataaaa caactgccca aaacattgtc atttatcgtg aagaaaacgg agaattcacc
     4021 gcacgaactc aattgaaaaa agtgccacgc ttaggaccaa aagcatatga acaagcaatc
     4081 ggattcttgc gagtccctgg tgggaaaaac attttggaca acacaggtat ccatcccgaa
     4141 agttattcta ttgcaaaaga aatattaact tcagtccaac tttcagaaaa agagcttggt
     4201 acagaagaag cagtagaaaa attgacacga ttatccgtag agaaactggc tgaaagccta
     4261 tcagtcggag aagaaacgtt agccgatatt ttagctgggc tgacacaacc tggacgagat
     4321 atgcgtgatg agatgccagc gcccttatta cgtacagatg tattgagtat ggaagacttg
     4381 aaaccaggga tggaattgac tggaacggtc cgtaatgtca ttgacttcgg cgcatttgtt
     4441 gatatcggtg tgaagcaaga cggacttgtc catatatcga aactcagcaa aaaattcgtc
     4501 aagcatccta cagatgtcgt gtcagtagga gatatcgtaa cagtttggat agaacaagtc
     4561 gatacgaaaa aaggtagaat cagtttgacg atgctttccc cttatgaaga gtaacaatga
     4621 ggagtaacaa aaattgacac aagaagaact gcagcagtta gtagaagaga tatcattaaa
     4681 aagcttccag cttcctttca agcaccaagc aatgttcaat ccacgcttac gtacaactgg
     4741 cgggcgctat catttaaacg atcatcattt agattttaat gcgaagctat ttgaagagtc
     4801 agacgaagag acgattgcag gaatcatcaa acatgaactt tgccattatc atcttcatct
     4861 agctggaaga gggtatcagc ataaagatat ggatttcaag tatcttttga aaaaaacagg
     4921 agggttgcgc tatgcaccag ccttgacgaa gaaacagata aagatggagt attatcgatg
     4981 ccaagattgt tctgccacga tctgccgcaa gagaagaatc gatgtacgca aatatcgttg
     5041 tggaagatgt catggagaaa tcaaatggat tgagacaaaa agagaagact ttaatgaagc
     5101 acaaaaaatc agatgaaagg atagaaggcc tttggaaaaa agtgagcaga ggaatctaaa
     5161 agactggaat cagctattaa attttttagc cgcacctgaa gagggaaatt ttgaggaact
     5221 gacggcacct acacttattt tagctggaaa ctgtcttcct atcttagctg ataaagcagc
     5281 acaaatgtat ttaaatggcc aagtagatca attgtttttg gtcggagggg tggggcatgc
     5341 gactagaatc ctttatgaga attttgaaaa gcaaggattt cattttgaag atggcatgag
     5401 tgaaagtgaa atctgtcgtc agtatctaaa agaagtctat gatttgcccg ataaggcttt
     5461 tctgatagaa tcgaagtcta caaattctgg agagaacgcc actttttcac tggagattct
     5521 tcattcctta ggagctgtac cagaaaaaat cttattgatg aatgatccga cactgcaacg
     5581 caggactcga gcaacttttg agaaagtatg gcaaaatgaa caaactattt tcgcgaatgc
     5641 tgtgccattt gtgccggaaa tccttcactt ttctgaagag atcatcttta cagcaaaaga
     5701 actgaatcat caatggccta aggaatattt ccatgcgcta gtattaggag aaatggaacg
     5761 tctccatgac gatgagaacg gctatggtcc gaaaggaaaa gattttattc ctcacattga
     5821 tatatcagag gaagtttggt cttcttacac cagaattaaa gagtcaataa aaacggattt
     5881 ttctcgtact tgaccatttt agcaagcgaa tcctcctttc caaataaatt tggttgaaat
     5941 tttcaatcgt ttataagata atgaggagcg tgttgaatgt aatagctaaa agaatggacg
     6001 ctagataaga gaagaggatt caaatggaaa atcaaaataa attgtatcat tttgttggta
     6061 tcaaaggttc aggaatgagc tccttggctc ttgttttaca tgaacaaggt ctaaatgtcc
     6121 aaggatcaga cattgaaaaa tatttcttta cacaaagaga tttagaaaaa gcaaatatca
     6181 cgattctgcc atttaacgca gataatgtaa aaccagggat gacgatcatt gcaggaaatg
     6241 catttcctga ttcacatgaa gaaatccagc gagcaaaaga attaggtttg gaagtgattc
     6301 gctatcacga ctttattggt cattttatcc aaaattatac gagtatcgct gtaacaggct
     6361 ctcacggaaa aacaagtacg actggactgc tctctcatgt attgagtggt gtccgtccaa
     6421 caagttatct aattggagat ggaacaggac atggtgatcc gcaagcggaa ttcttttcat
     6481 ttgaggcctg tgaatatcgc cgtcatttcc ttgcctattc accagactat gcaatcatga
     6541 ccaatatcga ttttgatcat ccggattatt atacaagtat cgacgatgta tttacagctt
     6601 tccaaacaat ggctggacaa gtgaaaaaag ctatttttgc gtatggtgac gatgcttatt
     6661 tacgcaaatt aaaagcaaat gtgccgattt attattatgg tgtcacagaa aacgatgata
     6721 tccaagcacg aaacatcgaa cgcacaactt ctggttctgc ttttgatgtc tatcatgggg
     6781 atgaatttgt tgggcacttc actgtaccag cattcggtaa acacaatatc ttaaatgctt
     6841 taggtgttat tgcagtagct tatttcgaaa aactggatct gaaagaagtt gcagaagaaa
     6901 tgctgacttt cccaggagta aaacgtcgat tcagtgaaaa gatcgtagca gacatgaccg
     6961 tagtcgatga ttatgcgcat caccctgcag agatcaaagc aacgattgat ggcgcacgcc
     7021 aaaaatatcc agataaagaa ataattgcag ttttccaacc ccatacgttt acgcgtacga
     7081 ttgcattgat ggatgaattt gcagaagcac ttgatttagc tgataaagtt tacttatgcg
     7141 atatttttgg ttcggctcgg gaagaacaag gaaacgttaa gattgaagac cttggagcga
     7201 aaatcaaaaa aggtggagaa gtcatcaaag aaaataatgt atctccattg ttagattatc
     7261 atgatgcagt agtaatcttc atgggtgctg gagatgttca aaaatttgaa caagcgtatg
     7321 aaaaactttt aagcagcacg acgaaaaatg tactgtaata caattactgc agtgtcctta
     7381 taaaaataga aagaggggga gtggcaaaaa tcttgccaag cccccttttt tgcaacttat
     7441 gataaacggt gttcaaaagc ttgcatctgc ggtaataagc ccaatcaaat caaaaacatg
     7501 agaagctgtt ttttcttggc tgttcttatt atttgatgca ggacagcttt ttcacgacct
     7561 ctgtaaacta taggaatctg ttaaatcaag ggagcagaac ttgcctttta cgctactttt
     7621 ggtacaataa tgtatgatta aaaataaact ggagggtttc tatcttgaac ataggtaagc
     7681 cgagaaaact aggaaaaaca ataaatgaaa tcgaggaagg cgactcgtta tccttaacag
     7741 aatctattga agataaccag cttttgctgt atttgggatt gacgaatgat gcaaatcctt
     7801 tgtatatcca acatgacttt gcacaaaaaa cagaatatca acagccaatc gttccatcag
     7861 tgatgctgat ggggatcatc acaagtgcaa tttcaaagca tcttcctgga ccaggatcac
     7921 atgttgtcaa tttttctgtc aattttattg aaccggtttt ccattatgaa acactgactt
     7981 ttcagtttga ggtcataaaa gtagataaga tgaaggatgt ggtgacgatt tctgtagaag
     8041 cggagaatac gaacgaagat cgtgtgttgg atgctgtcgt tatggtccaa ccgccacaag
     8101 ttcctgaatt ggaaatagca atcgaaagtg aaggtgaatt gaatgaataa tccaagtaca
     8161 tcaatgtcag gtatcaatcg tttttatgca aaagtttatg gatttttagg tatgggactt
     8221 gcccttagtg cagtcacttc ttacttggct ctttgggtat ttcctttgca attagcaact
     8281 tttatcaata attttccact aggctttgtg ggtctgtgga tcgttgaact gattttagta
     8341 atggttctag gcgtaaaagc acaaaagaat ccgagcttag caatcggtgg atttattgcc
     8401 tactctcttt tgaatggcat aacattagcg gttactcttg catactacga tattggaaca
     8461 gtaacgcaag ctttcttgac agctactttg atgttcatgg ggatgtctgt tgtcggagta
     8521 acaacaaaaa gagatcttag cggggttgga agagcaggac aggcagcttt aatcggagtg
     8581 atcattgcac tagtcttgaa catcttcatt ttgagaagta gcgtagttga gctgttcatc
     8641 tccctactgt tagtcgtcat ctttgcaggg attacagctt atgataacca aagcatccgt
     8701 aatatctatg tccagacaaa cggaacagca catagtggaa ttgctgtatt catggcattg
     8761 aagctgtatt tggactttat caacttgttc ttggcgtttc tgagaatctt tggacggaac
     8821 aactaaaaaa gaaaaaaatt catcagttgg ggctataccg aattatttgg tatggtcccg
     8881 ctttttcttt tcgcattccg caggattctt tgttagaatg aataagaact ttacagtaag
     8941 gagttaagaa gatgacaaaa aataaattat tactcgttga tgggaacagt gtggcttttc
     9001 gcgcattctt tgcgcttcac aattctcttg aacgtttcaa aaatagaaac ggtcttcata
     9061 caaatgcaat ctatgcattc aatacgatgt ttgaaaatgt tatgcaaaaa gagcaaccga
     9121 ctcatgttct ggttgcgttc gatgcaggaa aaacgacttt tcggacagaa atgtatgcgg
     9181 agtacaaagg tggaagatcc aaaacacctg gcgaattcaa agaacaaatg ccatatatac
     9241 gtgatttgtt gacaggacta ggggtacagt attacgaatt gcccaattat gaagcagatg
     9301 atattatcgg tactttggca gaaaaagtag acaaagatca atttgatgtc gtcgtgcttt
     9361 caggtgatcg ggatttgact caattagcta gtaaagaagt aaaagtggat atcactgtaa
     9421 aaggtgtcag cgatatcgaa agctatacac cagaacatgt agcggaaaaa tatgatgggt
     9481 tgacgccaaa acagattatt gacatgaagg gactagccgg agatgcctct gacaatatcc
     9541 ccggtgtgac taaaatcggt gaaaaaacag ctatcaagct attgaaacaa tatggctcag
     9601 tcgaaggaat ttatgaacat atcgatgaaa tgaagcaaag caaaatgaaa gaaaatctga
     9661 taaatgacaa agagcaggct ttcttatcga aaaaattggc gaccatcaat acttcagcgc
     9721 ctgtggatgt ctctatcgac tcattgaagt atgaagggaa aaatctcgat aaactcgttc
     9781 cgttttataa agaaatggat ttcaatcagt tcctttctaa attgaatatc gtagaagaag
     9841 aagtaaaaat ggatgatatt ttgtttgaag tcgttcatga attcaaagag gaaatgttta
     9901 ctacggatat ggcgttgtac gtggaaatga tgggcgacaa ttatcataca gaggaaatcg
     9961 tcggagtagc gtgggggaca gaaaagaaaa tttatgtcac gaacgatcta tctgtattcg
    10021 aaaaccgagc gttccattct tggatcactg atccgactcg gctgaaaaaa gtatatgatg
    10081 cgaaacgaac ttatgttgct ttaaaccgct atactggaaa aacgaaagga atcgattttg
    10141 atgtcttgct aggtgcatac cttctcgata cgaatgaaaa aagcacagat atcgaaggaa
    10201 tagctgctca ttacggatac aacgatatcc aatcagatga agctgtatac ggcaaagggg
    10261 cgaaaaaagg tttaccagaa gaagaggaac tcttttttgc tcatttagcg cgaaaagtag
    10321 ctgcaatcaa tgcgttgaca ccaaaattga gccaagaact ggcagaaaaa aaccaagaag
    10381 atcttttccg gaaaatggaa ctgccattgt ctatcatttt ggcagagatg gaaataagcg
    10441 ggatcaaagt agatgcgact cgcttacaag aaatgaaggg cgagttctct gctcgcttaa
    10501 gagagatcga acaaaaaatc tacgaagaag ccggcgaaga attcaatttg aattcaccaa
    10561 agcaattagg agtgatctta tttgaaaaaa tgggattacc cgttatcaaa aaaacaaaaa
    10621 ctggatattc cacagccgta gatgtactgg aacagcttcg tgaacaagca ccaatcgtag
    10681 aggatatcct cacctatcgt caaattgcaa aaattcaatc tacctatgtc gagggactgc
    10741 tgaaagtgat ccaatcagat ggaaaagtgc atacccgtta tgtccagaca ttgacccaaa
    10801 caggacgatt aagctctgtt gatcctaatt tgcagaacat cccgattcga ttagatgaag
    10861 ggagaaagat acgtcaggca tttgttccta gagaaaaaga ctggctgatt tattcttctg
    10921 actattcaca aatcgagtta cgcgtacttg cgcatatctc aaatgatgaa catttgaaag
    10981 ctgccttcct agaaggtcaa gatatccatg ccagcacagc gatgcgtgta tttggaatcg
    11041 aaaaggcaga ggatgtcaca ccaaatatgc gtaggcaggc aaaagcagtg aattttggta
    11101 tcgtgtatgg catctctgat tacggacttt cacaaaatct aggaatcagc cgaaaagcag
    11161 cacagcaata catcgatacg tactttgaaa aatacccagg tgtcaaagaa tatatggaaa
    11221 gaatcgtacg cgaagcaaaa gaccaaggct acgtcgaaac gctgtatcac cgccgtcgat
    11281 atctgccaga catcaattca agaaattaca atatccgttc ttttgcggaa cgaacagcta
    11341 tcaatacacc aatccaagga agtgctgctg atattttgaa aatcgcgatg atcgaattgg
    11401 ataaacgatt aaaagaaaca ggtcttcaag ctacgatgct gttacaagtt catgatgaac
    11461 ttgtcttcga ggtaccggaa aaagaacttg aatcattaga taaattggtg aaggaagtta
    11521 tggaacaagc tgtttctctt catgtaccac tgatcactga cagcagttgg ggaaaaacgt
    11581 ggtacgaagc aaaataaaca ttgtttaaga cagagcaata taatgaaggt gaaaagaaaa
    11641 aatgccagaa ttaccagaag tagaaaccgt tcgtaaagga ttggaacggt tagtagtagg
    11701 aaaaacgatt caaaaagttc aggtcttgtg gcccaagatc atcgagcaac cagagacacc
    11761 catctttgag gcttctcttg ttggcgaaac catccaatcc attggacgta gagggaagtt
    11821 tttaattttt catctcgatc attgtgaact gatctcacac ttgcgaatgg aaggaaaata
    11881 tcaatttacg aaagaaaata caccaatcga taaacatacg catgtacttt tcttttttga
    11941 ggatggaagc caacttcgct acaacgatgt acgaaaattt ggtcgtatga caatcgtcga
    12001 aaaaggagca agtgcaactt accgaggaat catgaaattg ggacctgagc ctttgccaga
    12061 tagcttctta ttagcagatt tcgcaaatgg actgaaaaag tcccacaaag caatcaagcc
    12121 attgctgcta gaccaacgtc tagtgactgg tctaggtaat atttatgtag atgaagcatt
    12181 atgggaagcg aagatccatc cagaacaacc ggcgaacaca ctgcgcccca aagaggtaga
    12241 acaattacgt ctatcgatca ttgatgtttt ggatcgtgca atagaagccg gaggtaccac
    12301 gattcgcagt tatttgaatg cattaggaga atcaggcgga tttcaagtag cactgcatgt
    12361 ctatcagcaa actggcaaac catgtatacg ttgtggaacg ccgatcgtga aaacaaaagt
    12421 ggcacaaagg gggacgcact attgtccgaa ttgtcaaagg ctaaaaatcg caaagtagga
    12481 tttgttttag gtttgacggg tggaatagct accggtaaaa gtacggcagc caaagtcttt
    12541 cagtctcatg gatttccttt gatcgatggc gatgtgattg ccagagaaac tgttgagcct
    12601 ggaacgcttg ctctgaggaa aattgtatca gtgtttggcc aagaggtatt gcagcctgat
    12661 gggcaactag atcgagggaa acttgggatg attgtttttc catcaaagga aaaacggcaa
    12721 aaacttgatc agctattaga tccgtttatc cgaaaagcga taaaagatca aatcgcctct
    12781 ctaagttcca atcatccttt agtaattgta gatatcccat tgctctacga aggtcattat
    12841 gaccactata tggatgcagt agctgtcgtt tatactacgc cagaaactca gcttcagcgt
    12901 ttgatgaaac gtaatcaact gacgctagaa caagcgcagc agagaattag tagtcaactt
    12961 ccaatcgaag aaaaaaagca gcgtgcggat attttgttcg acaacaatgg aacaaaagaa
    13021 aaacttgtgg gacaaatcga aaattggctt tttgctaatc gctttctttg agtatctgtg
    13081 tcaattttgc tatcctgagt atatagaaag tgagggatag cgatgggatc attaaaaaat
    13141 caaaaggata aagtcgtagg taacgcaaaa gaaaaaatcg gcgagatgct caataaagaa
    13201 aatctaatcg atgaaggtcg tacgcaatca gaaacagcag aagaaaaaga aaagcagtac
    13261 caagcaagaa tcgatgaaat agaagaccag caggcagaag aagaagcgaa gcggcaagat
    13321 ttgactcaag aacgaaaaaa tccgacacct gatcgtagta aaacaccgct cccagaaagt
    13381 gaccacattc ccgatgagca aaaaatcgag gaacagcgaa tgaaacacta tacaggaatc
    13441 gaagagaagt tataaaatag taaaaaatcg agatgtgact tgaagcagat gagaaggtgt
    13501 tcatctgctt caagtttttt gtgctagatg actaaatcag cttttgtgta agttatttct
    13561 cagtaatcaa ggtgatcagt attggaaaat tgaaatttag taaggacagg ggacacaatt
    13621 acgcatgaaa gtagaaaaaa ttgttcttat atccgtgttt tttgggtagg acagtcgcgt
    13681 ttgtgatttg tttcgtgtta taatacaact agttgtaaag aaagacacat cctttatata
    13741 aaatgcgatg caagaggtga gacaaaatga gatgtcccag atgtcaacat aataattcac
    13801 gagtaatcga cagccgtcaa gcagatgatg gacgtgcgat ccgtcgccgt cgcgaatgtg
    13861 agaattgttc gttccgattc actacatttg aacgaattga agctgctccg ttattagtaa
    13921 tcaagaaaaa cggggaacgc gaagagttca atcgcgataa aattttaaga ggactcatcc
    13981 gttcagcaga aaaaagacct gtagctatgg aacaaatgga acaaatcgtc aaccatgtcg
    14041 aaaaccgcgt acgcagtctc ggagaaaacg aagtatcgac gaatctaatt ggtgaatatg
    14101 tgatggaaga tttagttgat ttagacgaaa tcgcttatat tcgttttgca agtgtttatc
    14161 gccagttcaa agatatgtct gttttcttaa aagagttgca agatatcgtg gataaagcaa
    14221 aagaaaataa taaagagaat aataaagaaa acaattaaga aacaaaaagg aggcatttcc
    14281 ttggaaaatg cttggaaaga gcttcaacca aaaaatattt accaaggaag aaaagcggct
    14341 ccgctgagag aagacagcaa gaacgccttg ctgtatcttt atcagccact aatcggcgga
    14401 gaagccttga gtatctattt caccctgtta tcagaaatct ctcaagaatc tggcaaaggt
    14461 cctgaaggga tgcatgcaga tctgcttagt agtctaggct gcggtatccc gcaattttat
    14521 gatgcaagaa aaaagctaga aggaatcggc ttactggatg tttattttaa agaagatagt
    14581 gatctgggac ctcgttttat ttatgagctg ttagaaccac tcattcctaa agcatttttc
    14641 aaagactctg ttctggcttt tcttcttctg gaaaaagttg gtgaacgacg attccagaag
    14701 cttacccaat tctttgaacc taaaaggcat acagcagagg gatatcaaaa aatcacaaaa
    14761 aaatttttag atgtttatcg cttcaatgaa gcagtgtacg ctgctaatca agaaaacatc
    14821 gaatcgctga ataaatcttt tgaagaatct gaatcagtag cattacttga agcagattcg
    14881 acattcgatt ggcagttttt gaatgattgg ctggcaaaaa aacatattgc aagtcttgat
    14941 gatccaatca tcaaacaagt cgacatgtat catcagcttt acggtttcga tgaattgaca
    15001 cttggcgaac tgatcagtca atcttatgac tttagtgaac aaaaagtatc tgaaaaagaa
    15061 ctgcaaaaag ccattttggc aatgcagaga cgtccggtga agcaaacaaa agaaacagtt
    15121 gcggtttctg aaaacagtaa tgaaccctcg tcaaacgaac atttgacaaa cgcagcgctt
    15181 cagctgataa aagaagcaca gagcattcca ccgatgaaat atctggaagc aatcaagtca
    15241 gaaaaaggcg gatatgtttc taaacaagaa aactggttac tgcaagatct tgtttctcaa
    15301 tcaggtcttt ccagtagcgt gatcaatgtt ttgctgaatt atgtactagt gatcaagaat
    15361 aatgctagct taaatgccag ttatgtaaat acagtggcaa atgaatgggc acaaaagaaa
    15421 atcgccacag cagaagaagc gatccagcac attcggcaaa taagtaatca agcaaaacaa
    15481 tcaaaacaaa agaagcaaac aaattatcaa actggcaagc gaaatgttcg acgggaaaag
    15541 cttcctgatt gggtcaacca gccaaaagat gaaaaacaga tcagcagcga gaaaaaagca
    15601 gagattgacc gccgttttaa agaatacctg gcaaaaaagg agggtgatat ctagtggaag
    15661 acgtaggcaa agaattgaag aggatcatca gcaaacgcaa ttatcaagaa aagtatgctg
    15721 aaatgatcgc tgaagtctta aatgatgcgg atgttcaagc ttttctaagc gcacaccaag
    15781 aagaattgac acaagcggat attgaaaaaa gttacgctaa attgtatgaa ttcgtgcaag
    15841 aaaagcgtaa atatcaaaaa aacgatccaa cgatgatcgc tcccggctat gagccgaagc
    15901 tgacgttgaa ttttcattat gtggatgtca cttatgtacc aacggaagca ttgttagcac
    15961 ggcaaagaca agaagaaatc agaagccgag taaaagcaat ggatatgcca aaagatattc
    16021 aatcggcttc ttttgaaaac tttgaacgta cagatggacg aggatatgcg agcttagaag
    16081 ccctagattt tgtagagaaa tatactgctg atccaaaagg gtatcataaa ggactgtatc
    16141 tagtaggaag ttttggtatt ggaaaaacat atttattagg agcaacagcg agagaattag
    16201 cgattgctgg attcaccacg acgctagtcc attttccgac atttgccgtt gagatgaaac
    16261 aggcaatcgg aaaagatcaa gtggcagaaa agttagatgc agtgaaacgt tcacctattt
    16321 tgatgatcga tgacattggt gcagatgcga tgagtagttg gatacgagac gaagtattcg
    16381 gtgttatcct tcaatatcgg atgcaggaac agttaccaac cttcttctca tcgaatttta
    16441 caatggatga attggaacag catttgtccg tcactcaacg tggagatgaa gagccgctaa
    16501 aagcgaaacg gataatggaa cgcatacgtt atttgacaaa agaaatcgaa atgactggtc
    16561 gcaaccgacg caatggttga acagttgaca agtccaactg acatttgacc tagtagtaaa
    16621 agcaggtcag cgaatcatta tatggacaga aatgaccgga gacaatcacc gcaacaagta
    16681 atgcagaaac ttaaacggag gattttttat gagggctatt ttttctagta tatctgtagt
    16741 tggtctattt tttcttttag caggctgcgg tagcgcagat agcaacacag gttctgttga
    16801 ttcgattgat gcgggtcaaa cagtaaaaac aagcagtacg aaaacggaga gacaaagcat
    16861 atttgtcgga acgattgaaa gtatcactca agtagaagca gaagaagaaa cgcttcagtt
    16921 gaaactcgtc gatgtcatgg ccaaagaaga tccagcgaat atgggaacgt cattcagcaa
    16981 tgacggagtg atcttaaatg ctactgctga aaaaataagc gtggacataa atgaattgaa
    17041 aatcggtgac aaagtccaat ttacattagt tgagatgccg atcatgacga tgtctatccc
    17101 accgcaagtt cctggagatt cgattattga tgtttcattg aacaaataac caataacatt
    17161 ttttcaaaaa taagaaaatg ttgttttata gaacgaaaag gtatattttt taaggagata
    17221 tgggaatttt tttattccta gtctccttat tttatttgga aaatgctata attatctaga
    17281 aggagtgaag ctatgaacca tttagattta tctcagcgct tagccgcagt gggtgacttt
    17341 gtccctgaat ccgctcgttt agcagacatt ggatcagatc acgcttactt acccgttgca
    17401 ttgatattaa gaggaaaaat cgaatatgca gttgctggtg aagtcgttca aggtccttat
    17461 gaatcagcac gtaagcaagt caaaaaagat ggattagaag accgtatcac cgtacgcctt
    17521 gcaaatggtc tagatgctat ccagccacaa gatggtatta cagctgtcac gattgcgggt
    17581 atgggaggtt cactgatccg agatatccta gaagctggca agttgaatca acgcttaagc
    17641 ggacaagaac gtttgatcct tcagccaaac atcggagagc gtacattacg atcttggctg
    17701 caagaaaatc agtataaaat ccaatcagaa aaaatacttg aagaaaataa aaaaatatat
    17761 gaaatcattg tagccgaaaa agaacaaaaa ccagttactt acaatgaaat ggagctgatg
    17821 ttcgggccat ttctgcttga agagaaaagt gagatcttca aatcaaaatg gacaagagag
    17881 cttcaacaaa gaaaagctat ccgtgaacag ctcaaacaag cagctaatca agaggcacgt
    17941 caaaaacaaa tcgagcagga aatccaaatg attgaggagg ttttaaagcc atgacaatca
    18001 gcggacgcac tttcatccaa aagtttgaaa gctattgtcc tcagtggcta gctgaagaag
    18061 gagacccagt cggactgcat atcggaacat tggataagcc aatccaacga gtaatgatga
    18121 cattagacgt tcgtccagaa gtggtcgaag aagcaatcaa gaaaaaaatc gatttgctga
    18181 ttgctaaaca tcctccaatc tttcgtcctg taaaacggct ggttactgat cagccacaag
    18241 aaaaaatgta tgcagatttg ttgaaacatg atattgccgt ctatgcagca cacacgaaca
    18301 tggatattat ttgggatgga ctgaatgact ggttttgtga acttctcggt attgaagtgg
    18361 agagttattt agtaaagact catgagattc attataaaaa actggccgtt tatgtacctg
    18421 tggatcatgc acagaaaatg cgtgaagtat tagctgcagc tggtgctggt acacaaggtg
    18481 attataccgg tacaagtttt acctcgattg gacacggtcg atttactccg gaagctggtg
    18541 cacaaccagc gattgggaaa gtagggaaga cagaacaagt tcaagaggca aaagttgagg
    18601 ttattttgcc ggaaactatc gaaaaacaag tgattcaagc catgcggtca gctcatcctt
    18661 atgaggaacc tgcttatgat cttttcgcta tagatgaacc agtcgaaatg tttgggttag
    18721 gacgagtagg tgaattgccg caagaaattt ctatagaggc atttgtagaa caagtaaaag
    18781 aagcgttcca actagatgga ctgagaatag tccagccaaa aaatgcaaaa tcctctgtga
    18841 agcgcattgc gatttgcggt ggaagcggtg aaaaatttta tccgcaagca atcgcccaaa
    18901 gagcagatgt ctatatcacg ggagatatct attatcatac ggctcatgat atgcaaagcg
    18961 ctgggttgat tgcaattgat cccggtcatt atattgaatc gttatgcaag caacgattta
    19021 tcgagaaatt tgaatcttgg aaacaagaag aaaattggga tattaacttt ttcgtttctg
    19081 aaacaaatac aaacccattt caatttaatt aaaaggagag aatactatgt acgaaaatct
    19141 tttgccacgt tttttacgat atgtcaaaac agaaacacgc tccgatgcaa caagcaaaac
    19201 gactccatcg actcagacac aagttgcttt tgcgcaagaa ttgaaaaaag aattagaaga
    19261 gttaggctta gctgatgttt tctataatga agataacgga ttcgttatgg gaacattacc
    19321 aagcaatgtt gatcatgaag tgcgttccat tggatttatt tcccacatgg atacagcaga
    19381 ttttaatgca gtaggagtca atccacaaat cattgaaaac tatgatggcg agtctacgat
    19441 cgtactagat gcggaagaac gctatacatt gaatacaaaa gtttttccaa atttgaaaaa
    19501 ttatgaaggc cacacattga tcacaacaga tggcagtaca ttactgggag cagatgacaa
    19561 atcagggatt gcggaaatca tgactgcaat ggagatcttg atcaataatc cttctatccc
    19621 tcacggtacc atcaaagtgg cttttggtcc tgatgaagaa atcggtgtcg gagcggataa
    19681 attcgatgtt gagcaattcg atgtagattt tgcttataca gtcgatggtg gtcctttagg
    19741 tgagttgcag tatgaaacgt ttagtgctgc tcaagcaaat attacgatcc aagggaaaaa
    19801 tgtacatcca gggacggcaa aagatacaat gatcaatgct ctacagttag caatcgattt
    19861 tcataatcag cttccagccg atgaagttcc agaaaaaacg gaaggatacg aaggtttctt
    19921 ccatttgatg gcattggatg ggaatcctga agaagcttct atgagttata tcattcgcga
    19981 tcatgatcgt gaaaaattcg aagcacgcaa agcacaaatc acacatatcc aagaagagtt
    20041 gaatcagcga tttgatcaag aacgaatcaa agtagatatg tatgatcaat attacaacat
    20101 gaaagaaatc attgaaaaag atatgagcat cgtggaatta gcgaaacaag caatgatcga
    20161 gcttggtatc tctccagtga tcgaaccagt tcgtggagga acagatggtt caaaaatctc
    20221 ttacatgggt attccgacgc caaatctatt tgccggagga gaaaatatgc acggacgatt
    20281 cgaatttgtt tctttacaag taatggaaaa agcaacagac gtgattgtaa aaattgcaga
    20341 attgaacaca aagagttaaa atcgaaaaag aacagcttat gacaaggcgt tcgtcccaat
    20401 gatggaatgt catctgtcta aggctaaagg gcaggacaat ggaattggtt gtcccgccct
    20461 cttttttgaa gagtaaatag gaggtaaaga atggaaaagc tgctagtttt ttataacaaa
    20521 agttcaggga aagatgaggg tgagaaatta gcacgctggt ttcaagatta tgtaaaagaa
    20581 aagcagccag aattatatgt agaactagct gaaactggcc catcgattga tgatgcggaa
    20641 ttagtcaaga aagcagaagc catagaagct gatactttag taattatagg tggagacggc
    20701 acgattcatc atatcgtcca agcgttccaa aaaacattat ctcaatacca tgtcggatta
    20761 cttccaggtg gaactgtcaa caaccttgca cgtgttcttg agattcccct caaaaaagaa
    20821 gaagctgctg acgtgatcct ggaaggcaat gtacggaaaa tagactatgg tcaagtcaat
    20881 gatgaagtca ttatctctac actgacaatc ggaatcttag cagatacagc agtttggatc
    20941 agtcaagaag aaaaacagcg ttacggctcg tggatcttta tcaagaagtt ttttaagtta
    21001 ttgctgaaga agaaaaaata tcatttggat ttagaaacag acgaggagca ttggaaagga
    21061 aaatcccaac tgttgacagt cacgatgtct aactccgtgg gcggttttac aaattttgac
    21121 gactcagcga ccctagatga tggaaaattt catgtaacga tcgtaccttc cttagatatt
    21181 ttccgattta ttttttattt gcctagaatc atgagaggca aattctatac gatccccggc
    21241 attacttatt tcacagccaa acgcatgaaa atccaagcgc aggaaaaatc tgtgggcact
    21301 cgaacggatg gagacacgac agatgatctt ccagttgaat tatctgttgt atcaaaagga
    21361 ttaacagttt attcaccaaa gaaagaagaa aaagcttaga aatagtagtt aacagaaagt
    21421 tggaagaaga gtaatggatg tattgttaca caatcctttg tggttttacc ttttcattgt
    21481 gaatttttac ttattttgtc tgatggggta tgataaacat caggctagaa ctagcggctg
    21541 gcgtgttcct gagaataatt tgatatttgt cagcctgtta ggcggtggtt tgggaggatt
    21601 gatctctcga aaagttttcc atcataaaac tcggaaaaag aagtttacta taggattcgc
    21661 tgcaggtgta cttgttgatt tgattctcat ttattttttc cattaaggag caggagatgt
    21721 cgtctaaagg aacgaaaact aaaatcattc tgaatctgct tttgctgatt gtgatttttg
    21781 ccattattta ttatttaatc aatcaatcat ttgcagatat ctttgccgaa ttgctgtcta
    21841 ccagtgttgt tgttttggca gcggctgtta tattagggac agtttaccaa atcgctgaag
    21901 ggcgctcaat caaagaaatt gctgaacctt tcgcgccgaa ttttacaacg aaagatgggt
    21961 tcttgacctc tagctatatt gcgttttacc gaatcgtttc gtttggtaca ggaacgctga
    22021 tctcggagat ttatttttat aacaaaaaag gaatgaagct atcccaggga gcaggggtga
    22081 cagcactcca tatgattatg tacaaactgg cagtgatcac ttatgcatta gctggcttgg
    22141 tcatccaatt ctctcttttt tattctaatg gtccatcaat gatctggttt atcatcgctg
    22201 gtatcctttt gacgatcgtg attgttgcct ttttattggc gatgtccgtc agcttgaatg
    22261 ttcaaatatt ttttgtcagc ttatcgaata agttatttaa aagtgagcgt ttgcggaaat
    22321 gggtggatac atgcaatcag cagatctact ctttaaggga aacggtccaa accattatcc
    22381 aagacaggac tgcgctattg cggatttatc tatggaatat gttaaaactt gtattttggt
    22441 atgtacttcc ttatttgatt ctgattgaaa accatcctaa aatagatttt ctactgacca
    22501 tttcgtttat cagctttgca gtagtgcttt caggggttat tcctacgcct gctggtattg
    22561 gttcctttga atttgtctat ttgttattat tcagaccagt tgttggaaca gttgacgcag
    22621 tttcttcgct tttactgtat cgtttcagtt cctttatctt gccatttctc tatggatttg
    22681 tgtatgtgat tgctgaacgg cgaagagtga tcaaagaaga aataatagaa gtaaaaaaag
    22741 agaataaaga aaatcaaggg taggtctttt ataagatcta ccctttttat caaatcaaag
    22801 aaaaacgtta tggataagat aattttacgt ttgtttggct ctttttttat atacatacaa
    22861 tcaattttgt ttttttaaga tttatataag tcgagaaaaa aagtcaaaaa actatgtgta
    22921 tattttgacc aaaattgacc aaagcgatat aatagttttt gtaaagatca aagaaataag
    22981 tgatcttacc tttaattagg agggtatacc tgtatgaata ttgagaaaat gactacgacg
    23041 cttcaagaag cgattgctga agctcaacag attgcggtca ctcgaaaaca tcaagatatc
    23101 gacattgccc atgtatggaa aatcttttta caatctaatc attttggtcg aaatttctat
    23161 acggatgccg gattggatgt cgaatctttt gaacatgaaa ttgatcgtct actggatgag
    23221 tatccagttg tttctggtgg aaacgtccaa tatggacaaa acctcagcca gaatttcttt
    23281 cgattattga atgaagcaga ccaaatacgt gaaagcttcg gcgacgagtt tctttcaacg
    23341 gaagtcgtta ttttagcgtt gatgaaatta aaaaattatc cgttaactgt ttatttgaat
    23401 aaaaacggat tatctgaaaa agaattgcgt aaaaacatcg aagagatgag aggaggagaa
    23461 agagtgacct cacaaaacca agaagaacaa tacaaagcat tagaaaaata cggcgttgat
    23521 ttagtacagc aagtcaaaag cggaaaaatg gatccaatca tcggtcgtga tgaagaaatc
    23581 cgtgatgtca tccgtattct ttcacgaaaa acaaaaaata atcctgttct gataggagaa
    23641 cccggtgtag ggaaaacggc aatcgttgaa gggcttgctc aacgtatcgt acgcaaagat
    23701 gtgcctgaaa atttaaaaga taaaacgatt ttttcattag atatgggtgc attgatcgct
    23761 ggagcaaaat tccgtggtga atttgaagaa agactaaaag cagtcttgaa agaagtcaaa
    23821 aaaagtgatg gacgtatcct cttgttcatc gatgaaatcc acaatatcgt aggggcagga
    23881 aaaacagaag gaagtatgga tgccggaaat ctgttgaaac caatgcttgc tcgcggtgaa
    23941 ttacatttga tcggtgccac aactttagat gagtaccgtc aatatatgga aaaagacaaa
    24001 gcgttggaac gtcgctttca aaaggtatta gtcaaagaac caacagtgga agatacgatc
    24061 agtattctgc gtggattaaa agaacgtttt gagatccacc atggtgttaa catccatgac
    24121 aacgcattag tagcagcagc tactttatct gaccgttata ttactgatcg gttcttaccg
    24181 gacaaagcaa tcgatttgat cgatgaagcc agtgcaacga ttcgggtaga aatgaactct
    24241 atgccaacgg aattagatca agttactaga cgtttgatgc agttggaaat cgaagaagct
    24301 gcactgaaaa aagaatcaga tgatgcaagt aaaaaacgct tgaaaaattt gcaagaagaa
    24361 ttagctgaac ttcgtgaaga agcaaatgcg atgaagatgc agtgggaaac agaaaaagaa
    24421 gaagtcaatt ctgtttcagc aaaacgtgct gaaatcgata aagcaaaaca cgaattagaa
    24481 gatgcagaaa ataactatga tttagaacgc gctgctgtat tgcgtcatgg tacgatacct
    24541 caattagaaa aagaattgaa ggaattagaa gctaaagcaa aagacagcga gattaagatg
    24601 gttcaagagt ccgttaccga aaatgagatt gctcaagtcg ttggcagatt aacgggtatc
    24661 cccgtaacga aacttgtaga aggtgaacga gaaaaactaa ttaaattgaa tgaaacactt
    24721 cataaacgag tgattggtca agatgaagca gttgatgcgg tcagtgacgc ggtaattcgt
    24781 tcacgggctg gattgcaaga cccaaatcgt cctctaggtt ctttcctttt cctaggacca
    24841 actggtgtcg gaaaaaccga attagcgaaa gcgttagctg agaacttgtt tgactcagaa
    24901 gatcatatgg tacggatcga tatgagtgaa tatatggaaa aacatgctgt gtctcgtcta
    24961 gtcggagctc ctccaggcta tgtaggttac gaagaaggtg gtcaattaac ggaagctgtc
    25021 agacgaaatc cttatacaat cgtcttgttg gatgaaatcg aaaaagcgca tcccgatgtc
    25081 ttcaatatct tgttacaagt cctagatgac ggacgcttga ctgattcaaa agggcgagta
    25141 gtagatttca aaaatacggt tctgatcatg accagcaata tcggttcaca gttactgctg
    25201 gaaggcgtga ctgctgatgg aacgattcca gaagcagtgg ctgaacaagt caacacgcta
    25261 ttacgtggaa acttcaaacc agaattcttg aaccgaatcg acgacacgat tttatttaca
    25321 ccattgagcc tagacaacgt gaaaggaatc gttgacaaaa tggtggcgca attggcacaa
    25381 cgtctggaac atcaagaaat cctgctgaca atcagtgatg aagccaaaac gtggattgct
    25441 gaaaatgctt atgaaccagc atatggtgca agaccattga aacgatttat cactaaggaa
    25501 gtagaaacac cactagctaa agaaatcgtt gcaggacatg ttatgcctaa atcaaaagta
    25561 acgattactt tacttgatgg acaacttcat ttcaaaacag aagagctaga agaaatcgtc
    25621 taatcttcca ttgagactat aaaagaaaaa aggggtctga cacaactagt gtcagacctc
    25681 cttttttcaa ataaacagtg ttccagaagt agtttcttcg aaaaataagc cgaaatttct
    25741 tgaagctgcc cgcttctgtc acaacctctt ttattaggta tttttcactt tttctaattt
    25801 ataactttca aagtaacgct catctttttt actttgagac catgcaaaca atcccattaa
    25861 ggcagcacct atcgtatttg tcagcaagtc gcccatcgta tccatcaatg ctgctcgtcc
    25921 gacaaacagt gtgccatcag aagcagcaaa acgttgaaga ttcatgccta agaactggtc
    25981 gcataagaat tcccagaact cccaaaacac gccgcaaagt ccagcaaacg caaagccgaa
    26041 taagaggaac aaccaaggac tggtttttga tatctcagca tctttcatca agtaaccaat
    26101 caatccatag ccaagagctg tcaggaccat tggactcacc gcatgtaaga ttttgtccca
    26161 aaaagagatg atactgatca aatgcatccc tgtgcctaaa aagacagaga tgaacaagaa
    26221 aaaccagtaa aacaaaacga ttgctgctgg tattttaagt ttgaaaactt tcaaaatgac
    26281 ttgtggcatg aaaatcaatg caatccctaa taaagattcc acgataaatg tgattccttg
    26341 agaagtcgaa tatttttgtg tgataaattc ataaaaatta tagcagacaa cgaatacacc
    26401 aaaagcaagt aaagctattt gcaccttttt gatttcttta atcactgaaa gtccctccat
    26461 ctaaaaatct ttttacttct gaaagcaact caatttctga agaaaccact tttccgttca
    26521 atttgatcaa acctattgta tataagttca ggtagtgaaa ttgattttca gctgtttctt
    26581 gtagtgcagc gatttttttc gggtgggttc cgccttgctg tcgagtatca gtatataagc
    26641 cgatcactgg gatgcctttc gcataagcca caccgatttc cgatgctacc ccggcatcga
    26701 tcgtcagccc atctagtaaa gcaatcatta aatcactagc caacactttt tctgtgtcag
    26761 caagagcaat cattcgactg tctgcataag cagttttgtc attgattgct tcattttctt
    26821 gaggaagata gatcgaaagc tcagaagaga gctctctgat ttctttaact aactgttggt
    26881 tatataacaa atcactttta gcaaacattg gtgcggcaaa ataaattttc atctaaacat
    26941 catccttttt atcaaaaata atcgctaaag taagcttcca tgtttggaat gatacgctct
    27001 agtgacttca gtgtttcttc atctgtttct aaccgttcga ttcttgccaa ataagaagca
    27061 cggcgataat tcatcatcaa gcaagtcaat gtttggatat ccagtcgaac ggattttcct
    27121 ataggttcat ttaagacacg gacttgtccc tgttcatccc atgttaaagc gaagacacca
    27181 ttattccaag gagcgacagg atcttcaatg atgaaatgaa aagcatcagc tgttccaaca
    27241 aacggaaacc gttgaaggaa ttcttttaca tcaacgatcc gagccataaa atatggttcg
    27301 atctgctctt tgatctgact atcttcaatc aaaaatgcta aaggctcatt tttataaata
    27361 tctccatgta cccagtagat catggaaaaa tgtgcggaaa taaagttcca taagccattt
    27421 cgagcttctt gatcaagata gaacatttct tttacgtgaa atatttcttc agctacccag
    27481 tagaacagaa cacctcttgg ttcatggttg ctatcgtagt agacagcggc tgtgcgctca
    27541 tcttcatttt cgaaacgcca atactcttcc caatgaaaat cactgcggaa taaagcacca
    27601 tggttttgtt gggcaaattt gtcataaacg gaaaatacgt ctggatgatc aactggtaat
    27661 cgctcaacca taccacttac tgggatttgt ttaggtagct gtgtatctct gattttaaag
    27721 gaaagtttat cagacatgat ttcccatcct ttacgccgat agtaggggat actgtaagga
    27781 tacaaataag agatccattg cttattcttg cgcatattat ccaatgcaac gataattaga
    27841 tcttgcatca atccatggtt agcatattct ggataagttc caactccagt cacaccaccc
    27901 attttataac gtgcaccgtg aatattgact tcacaaggat agatagcgat ttgagagatc
    27961 agtttatttt cgtggaacca tccgaacact ttcgatactt ccaaaatcgg ttttttggaa
    28021 cggataaaag ctcgtttatt ctcaaacccg ctttcctcga tgtctgcttc agtcacttgg
    28081 aacacatagg aaagcaattc attgaattga tcgatatgtt cttgagtgac cggttttaat
    28141 tcaagatttt ctctaaaatc tttttgatcc attttttcat ctccatttat tagcttgata
    28201 acagtatagc aaaattctac aaaaaaaact tctatagctg actaattaaa aactctttaa
    28261 attactgctt ttcgttggta taatggaaag tgctgattat atgaaaagag gagacgctat
    28321 ggatataaag aaaatgaaag aacgccaaga gcagattcgt aatttttcga tcatcgctca
    28381 tatcgaccat gggaaatcta cattggccga tcgtatttta gaaatgacgc acactgtgac
    28441 gtctcgcgaa atgcaagatc agctgttaga ctcgatggat ttggaacgtg aacgtggaat
    28501 cacgattaaa ttaaatgctg tagaactcaa ttacacagcg aaaaatggag aaacatatat
    28561 ctttcacttg attgacaccc cagggcacgt cgacttcacc tatgaagtct ctcgaagcct
    28621 tgctgcctgt gagggtgccg ttttagtggt cgatgcagca caaggaatcg aagcacaaac
    28681 attggccaat gtttatttag cgttagacaa tgatttggag atcctgccag tcatcaataa
    28741 aatcgaccta cccgcagcag atcccgaacg tgtccgtcaa gaaatcgaag acgtaatcgg
    28801 aatcgatgct agtgaagctg tattagccag tgccaaatca gggattggga ttgaagatat
    28861 tctcgagcag atcgtggaat atgttcctgc accaagtgga gacttagatg caccgctaaa
    28921 agctttgatc tttgactcta tttatgatag ttaccgcggt gttgttctaa atgtccggat
    28981 cacggacggt atggtcaaac ccggagacaa aatcaaactg atgagtaatg gcaaaacatt
    29041 tgatgttaca gaggtcgggg tcttctcgcc aaaagcagtt gctagagact ttttgatggt
    29101 cggtgatgtc ggttatatca cagcaagtat caaaactgtc caagatacac gagtagggga
    29161 tacagtaacg ttagcagaca atcctgccgc tgaagcttta ccaggttacc gaaaaatgaa
    29221 tccgatggtt tattgtggtc tttatccaat tgatacttct cgttacaacg atttgcggga
    29281 agctttagaa aaactgcaat tgaatgatgc tgctttacaa ttcgaaccag aaacctctca
    29341 agcattaggt tttgggttcc gctgtggatt cctcggactt cttcatatgg atgtcgtcca
    29401 agaacgcttg gaacgggaat tcaatctaga attgatcacg actgcaccat ccgttattta
    29461 ccatgttaat aaaacggatg gtacgactgc tacagtagat aacccggcag attttcctga
    29521 acctgtaacg attcaggatg tagaagaacc attcgtcaaa gcacagatca tggtcccaaa
    29581 tgattttgtc ggtgcagtaa tggaactttc tcaacgaaaa cggggagaat tcattacgat
    29641 ggattattta gatgattacc gagtaaatgt cgtctataat attccgcttt ctgaaattgt
    29701 ctttgacttt ttcgacaaat tgaaatcaag cacgaaaggc tatgcctcat tggattatga
    29761 aatgtctggt tatcaaaaaa gcaagttagt gaagatggac atcttgctga atggagaaaa
    29821 agtcgatgca ttaagcttta tcgttcaccg agactttgcc tatgaacgtg gaaaagcaat
    29881 cgttgaaaaa ctgaaaaaac taatcccacg ccaacaattt gaggtgccaa tccaagcagc
    29941 tattggacaa aaaatcgttg cccgttcaga catcaaagcc ttgcgtaaaa acgtcttggc
    30001 taaatgttat ggtggagatg tttctcgtaa acgtaaactc ttagagaaac aaaaagaagg
    30061 gaagaagcgg atgaaacaaa tcggctccgt cgaagttccg caagaagcct tcatggccgt
    30121 tctgaaaatg gacgaggacg aaccgaagaa atagcaaggg tttgtttgaa aacagtgtaa
    30181 aaaataaacc atgtttacat ggatttgcca ccggtttgcc accggtggtt tttttcggtg
    30241 gcaaaaatca agaattcttt ctaagatttt ccatgatatc gaccgtttca tttctcatct
    30301 tatctgttac atgcgagtaa gtatccatcg taattgaaat tctgctgtgg cccaatcgtt
    30361 cagagatttc tttcattttt gcgccatttt cgagaagaag tgtagcatga gtatgtctga
    30421 gagaatggaa gttaaaagag agggagagtg cattcgatat cctcctagta ttccatttca
    30481 ctacacttgg cgtaactagc tcaccgtctt ccttcgtaca tactgcattt gaatcaatgt
    30541 agagctttcc atacttcatt cgattttcta attgttgttt cttatgtttt ttcagaattg
    30601 ctagcaaggt ttgtccaata aaaatcgttc gattggaact gcttgtcttt ggcgtaccat
    30661 atacccatgc gccgtcattc tttaccattt gtttctctac agtaattgtt ccatttgaaa
    30721 aatcgacatc atcccacgtc agaccacaaa cttcgccaac gcgcattccc gtataaaatc
    30781 caatattcaa aggaatatag aaaggatgtc cttcaggagt aatttctagc atatgatcaa
    30841 agtcctcaag agaaatgatt tttagatctt ttttagtcgt tggtcgtgct tcatattttg
    30901 gtatttttac atacagcata ggattttgct tgattaatcc ccaaggataa accgccatat
    30961 tcagcgcatt cttaaggaca gagtgagtaa tagtcattgt tttcttcgag taaccctttt
    31021 taaattcagc attgatgaaa ttttgtaaaa gagcagggga gagatccgta agttttttct
    31081 ttcctaaata accgtttata tgatttttga tggtaaatcg gtagttttca taggtattgt
    31141 attttagatt tagtttaacg tattcctcca tccaaaaatc aaggtattgt tttactcgag
    31201 tatccgtacc taaaaagtat tgtcctgttt cgtcaatatc tgataaaact tttcgtaaag
    31261 cagcttcggc ctctggtcgg gtgtctccgc caactttctc cacttttttt cttgagccat
    31321 catcattgat atct
//
LOCUS       DAYNVV010000027        31117 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.027, whole genome shotgun sequence.
ACCESSION   DAYNVV010000027 DAYNVV010000000
VERSION     DAYNVV010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31117
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.027"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(334..696)
                     /locus_tag="ACGXWR_001442"
     CDS             complement(334..696)
                     /locus_tag="ACGXWR_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803023.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(770..1150)
                     /locus_tag="ACGXWR_001443"
     CDS             complement(770..1150)
                     /locus_tag="ACGXWR_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvfD/Ygs/GSP13 family RNA-binding
                     post-transcriptional regulator"
                     /protein_id="HFK0803024.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1232..2407
                     /locus_tag="ACGXWR_001444"
     CDS             1232..2407
                     /locus_tag="ACGXWR_001444"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFK0803025.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2484..3068)
                     /locus_tag="ACGXWR_001445"
     CDS             complement(2484..3068)
                     /locus_tag="ACGXWR_001445"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFK0803026.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3269..4267
                     /locus_tag="ACGXWR_001446"
     CDS             3269..4267
                     /locus_tag="ACGXWR_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFK0803027.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4379..4888
                     /locus_tag="ACGXWR_001447"
     CDS             4379..4888
                     /locus_tag="ACGXWR_001447"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HFK0803028.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(4918..5577)
                     /locus_tag="ACGXWR_001448"
     CDS             complement(4918..5577)
                     /locus_tag="ACGXWR_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HFK0803029.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5579..6343)
                     /locus_tag="ACGXWR_001449"
     CDS             complement(5579..6343)
                     /locus_tag="ACGXWR_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HFK0803030.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6351..7028)
                     /locus_tag="ACGXWR_001450"
     CDS             complement(6351..7028)
                     /locus_tag="ACGXWR_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HFK0803031.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7065..8450)
                     /locus_tag="ACGXWR_001451"
     CDS             complement(7065..8450)
                     /locus_tag="ACGXWR_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HFK0803032.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8660..8744)
                     /gene="ffs"
                     /locus_tag="ACGXWR_001452"
     ncRNA           complement(8660..8744)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACGXWR_001452"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8767..9282)
                     /gene="tadA"
                     /locus_tag="ACGXWR_001453"
     CDS             complement(8767..9282)
                     /gene="tadA"
                     /locus_tag="ACGXWR_001453"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HFK0803033.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9389..10246
                     /locus_tag="ACGXWR_001454"
     CDS             9389..10246
                     /locus_tag="ACGXWR_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0803034.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10327..10662)
                     /locus_tag="ACGXWR_001455"
     CDS             complement(10327..10662)
                     /locus_tag="ACGXWR_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803035.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10729..12099)
                     /locus_tag="ACGXWR_001456"
     CDS             complement(10729..12099)
                     /locus_tag="ACGXWR_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HFK0803036.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12177..12713)
                     /locus_tag="ACGXWR_001457"
     CDS             complement(12177..12713)
                     /locus_tag="ACGXWR_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFK0803037.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            13022..14503
                     /locus_tag="ACGXWR_001458"
     CDS             13022..14503
                     /locus_tag="ACGXWR_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0803038.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(14606..15313)
                     /locus_tag="ACGXWR_001459"
     CDS             complement(14606..15313)
                     /locus_tag="ACGXWR_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HFK0803039.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(15392..15730)
                     /locus_tag="ACGXWR_001460"
     CDS             complement(15392..15730)
                     /locus_tag="ACGXWR_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HFK0803040.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(15841..16803)
                     /locus_tag="ACGXWR_001461"
     CDS             complement(15841..16803)
                     /locus_tag="ACGXWR_001461"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HFK0803041.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(16818..18149)
                     /locus_tag="ACGXWR_001462"
     CDS             complement(16818..18149)
                     /locus_tag="ACGXWR_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DRTGG domain-containing protein"
                     /protein_id="HFK0803042.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(18157..18837)
                     /locus_tag="ACGXWR_001463"
     CDS             complement(18157..18837)
                     /locus_tag="ACGXWR_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFK0803043.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(19056..19535)
                     /locus_tag="ACGXWR_001464"
     CDS             complement(19056..19535)
                     /locus_tag="ACGXWR_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HFK0803044.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(19662..21341)
                     /locus_tag="ACGXWR_001465"
     CDS             complement(19662..21341)
                     /locus_tag="ACGXWR_001465"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFK0803045.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            21889..23391
                     /locus_tag="ACGXWR_001466"
     CDS             21889..23391
                     /locus_tag="ACGXWR_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0803046.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            23404..24066
                     /locus_tag="ACGXWR_001467"
     CDS             23404..24066
                     /locus_tag="ACGXWR_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0803047.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(24167..24370)
                     /locus_tag="ACGXWR_001468"
     CDS             complement(24167..24370)
                     /locus_tag="ACGXWR_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFK0803048.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(24481..25665)
                     /gene="iadA"
                     /locus_tag="ACGXWR_001469"
     CDS             complement(24481..25665)
                     /gene="iadA"
                     /locus_tag="ACGXWR_001469"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008798 - beta-aspartyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HFK0803049.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(25822..27561)
                     /gene="yfcC"
                     /locus_tag="ACGXWR_001470"
     CDS             complement(25822..27561)
                     /gene="yfcC"
                     /locus_tag="ACGXWR_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HFK0803050.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(28334..28948)
                     /locus_tag="ACGXWR_001471"
     CDS             complement(28334..28948)
                     /locus_tag="ACGXWR_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFK0803051.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(29554..29931)
                     /locus_tag="ACGXWR_001472"
     CDS             complement(29554..29931)
                     /locus_tag="ACGXWR_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803052.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(30231..31112)
                     /gene="galU"
                     /locus_tag="ACGXWR_001473"
     CDS             complement(30231..31112)
                     /gene="galU"
                     /locus_tag="ACGXWR_001473"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFK0803053.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT         9285 a         6465 c         5191 g        10176 t
ORIGIN      
        1 aacgactcag ttatcttatc atgtcgttag taacatgtca ataactattt tttaaatttt
       61 ttagaaatgt gatataacat ccacttcaga atcaacgctg ttaaatttat catgtatttc
      121 ttccttggtc aactataaat taagcattac tttgtgaaat gatttttcga tcaattatta
      181 ttattcgtta tacaaccgtt ttcaacatat tttgaaaata aaatgcacta aaaaactatc
      241 tttagcagaa catttcattg tattttttgg accaaacaat aaaaaaagaa gtttgaaaaa
      301 aattcaaact tctttgttcg cttaatctgt attttagaag aaaggcactc cctctacttc
      361 gtaagttcca agaacagagc gcatttgacc tggttcttcc caaatatatc cttcgcctaa
      421 ttcttctctt tgattctttt gttcagtttc aaagacaaac aacggaacat tttcctcttt
      481 aatatgtgta tttgtcaatt ccatcaaact aatcttgcta acatcgatat gaactatttc
      541 ttttaagaaa ttaagtatat tcgctaaacc agtctttcct tcagaaagtt ccgctaacgc
      601 aaattccaac ttgtcatcaa ttgaatggac caaaaatttt ttagtaccat cctccaaatg
      661 caacataatt gtaccagcaa ctcttttgct tgccaaaatt tccacctcga tcaacttgtt
      721 ctatggctta cataaaaatt ctagcacatt ttcagaaaaa atacactttt tatttcttat
      781 tttctttccg ttctagttca gataatgctt cttctatcca aataggtaac tgctccgcaa
      841 tagtggtaaa tccgatctta cgatttttat tcgtgaaata cctttttctg cgatatggaa
      901 cagctggatt tgttttttct aacgttctta aagataaact gatttttttg gaatattcat
      961 caatgtcgat gatctgaact gttactggct gtccgacttt taacaatgaa tggatatttt
     1021 tcgtataacc ggattgtact tctgaaacat gaataagtcc ttgcgtctcg ttatcaagag
     1081 aaacgaatgc gccataaggc tgtatccctg tcacttttcc ttcaattatt tgtccaattt
     1141 tataagtcat ctacttccct ctcttcgcat ttatcattat actgtaaata gctcaaaaaa
     1201 agaagcgacg aaaatgactg gaggtcttaa gatgatcgaa tttgataaac agatttcaag
     1261 aaaagataca gaaagtgtaa aatgggacgc aattgctgag acatatcaaa tggatgactt
     1321 acttcctttg tgggtagcag atatggactt cttgtctccc ggtggggtag ctaaagcgtt
     1381 tagtgaatac atcaaacatg gaatctttgg ttatgccact ctgtctgata aactatatca
     1441 ggctatcatt cattgggaac gccaacacca tgctgtggag ttgacgaaag aaaatatcgt
     1501 ttttacaagt ggtgtgttaa ccagtttagc tgcagcagta caaactttta caaaaccagg
     1561 cgattctatt ttgattcatg acccagttta tcctccattt tcctctatta tagaaacaaa
     1621 tcaacgtcac atcgttcgaa gctctttgct agaaaaaaat aatcatttca tcatggactt
     1681 gtctgacatg gagaaaaaaa tcgaagaaaa caatgtaaaa gcaatgattt tatgcaatcc
     1741 tcacaatcct ggagggcgtg tttggagcaa agaagaattg aaacagttaa gcgaattgtg
     1801 tttaaaacat caagtgattc tgtttagtga cgagatccat caagatttaa ctttattcga
     1861 tcatacattt acttccatgc taacgattga tcctaattta gatgatctac tagttgcttt
     1921 tacttccgca accaagactt tcaatctagc tgcaatcaaa aattcaatgg tatttatcaa
     1981 aaatccagag atgaaagctg attttgaaaa acatttagtg atgaaccaac agcacgaaat
     2041 caacactttt ggactgattg gaacccaagc ggcttatgag acgggtggag aatggttaag
     2101 ccaactgatt ccttatctag aaaaaaatgt tcaaacagtt aatcagtttt ttgaacagta
     2161 tcttccgaaa gtgagaataa tgaaccctga aggaacttac ttaatgtggt tagattttac
     2221 cgcctatatt tcagacgacc aagaattgga gaacactctt gttcggaaag gaaaagtcgt
     2281 attaaatcct ggcatcacgt ttggtccttc cggtcatggg catatgcgct tgaatattgc
     2341 ttgtccagaa gaaactttac tggaaggact taatcgaatc aagtatgctt tagagacaat
     2401 cgattaaatc atttattcaa aataaaagga cgagacctta ctaggtttcg tcctttttca
     2461 taattactcc gtaccatacc aaactattct gaaatttcaa ttgtttcaat cactacatca
     2521 tgtacaggtc ggtcttgtgg accacgttgt acatttgcga tttcatctac tgtgtccatc
     2581 ccttctagta catgtccaaa gactgtatgt cggaaatcta gccaaggagt tccgccacct
     2641 ttatacgctt caatgatttc tgatgggaat ccagcacctt ctagttgtcc aagcatatta
     2701 gctggcacat ttgtgttatt tacaataaag aattggcttc cgtttgtgtt tggacctgaa
     2761 tttgccatag ataaagctcc gcgaaggttg aacagttcac gactgaattc atcttcaaaa
     2821 ctttcgccat aaatactttc gccacccatt cctgttccag ttggatcgcc gccttggatc
     2881 atgaaatcag gaataacgcg gtgaaaaatc acgccatcat aataaccttt tttggaaagt
     2941 tcaatgaaat tttgaaccgt cttcggtgct agttcaggga ataattgaac agtaatgtca
     3001 ccacggtttg ttttgataac agcttttggt cctttttcac tttttaaatc tagttgtggg
     3061 aatgccatat tgtttcctcc taatatttgc atacttcata ataataataa cataatacct
     3121 aacctctcgt aaaaatacta gatttgtttt cttttatttt tcatcactag atacattcta
     3181 taacttaccg tttcgatttc gaattcaaac atttttgaga agcattctca attaaattct
     3241 gctatagtgt gaaaagggag gaatttttat ggaaatctat gacattacaa tcatcggtgc
     3301 aggtcctgta gggatgtttg ccgcttttta cgcaggaatg cgccaagcta aaacaaaaat
     3361 cattgacagt ctacctcaac ttggtggtca attagcaact ttgtatcccg aaaaatatat
     3421 ttacgatatt cctgggtatc cagcaataaa agcaagtgaa ttaatcgatc aattagaaaa
     3481 acaattaact acttttaacc atacattcca tttaaaagaa gaagttctct cgcttactcg
     3541 tgaagacgaa gttatcgaga ttactacaaa taaaggcatc cattattcca aagcagtcat
     3601 tttagcttta ggaaatggtt cattccagcc aagaaaattg aatttagata atgctgaatc
     3661 atttgaaaac cacggattgg attatttcgt gaatgatttg atgaagtatg ctggaaaaaa
     3721 agtcgctatt gctggaggtg gtgattctgc tatcgattgg acgttgatgt tagagcctat
     3781 tgcaagcgaa gtttacttga ttcatcgtcg cccggaattt cgtgcgcacg aacatagtgt
     3841 atcacgcttg aaatcttcat ctgtcaactt gcttactccc tatctcatcg atggattatc
     3901 aggcaataat ggggaactga cagatatccg gttaaaaaaa gtgaaaagtg acgagacgat
     3961 tgatttgatg attgattctc tgatcgtcaa ttatggattc tcttctaatt tagaacatct
     4021 ttcttcttgg ggacttgata gtaccagaaa tgccattact gtaaaatcag atatgtctac
     4081 ttctattcca ggcgtttatg cagctggtga catctgtacc tatgaaggaa aagtgaaact
     4141 gattgctact gggctcggtg aagcacctac tgcagtgaac aacgctttac actatattaa
     4201 tccaaaggaa cgaactcagc ctggtcacag cacaagctta tacgataaaa atcttcgtcc
     4261 tagttgattt tttatatctc tttgcatttc aagttaaacc cgaaagcagt ttcttgcatt
     4321 tttttcatgt tccgttaaca tgaaatagag aaagaaaaaa taaaggggga gcaataatat
     4381 ggtcgtcaaa actgagactt tagaagaaaa ggcaagagaa ctattgaagg aacgtggcgt
     4441 aactgtagaa gatatcgcac aacttgtcat gtttttacaa aaagactata tttctgattt
     4501 gactttggcg gattgtactg aaagtgtcaa cagcgtgcta acaaagcgtg aagtacataa
     4561 cgccattatc actggaatcc aattagatat attagcagaa aagaaaaaat tgatgagtcc
     4621 gttgcaacat attatcgaag atgacgaagg cctttacggt atcgatgaga tcctagcctt
     4681 gtcaatcgtg aatgtttacg gtacgatcgg ctttacgaat tatggttata tcgacaaggt
     4741 gaaacctggt attttaaaag aactaaacag ccacgatggc gttcatgtcc ataccttctt
     4801 agatgatatc gtcggagcga tcgccgctgc tgctgccagt cgattagcac acaaagaacc
     4861 agaaaaaaga agtcgcctta ctcaataatt caacaaaaaa agaaagaaaa cgtctattta
     4921 gacgagttct ttcttttttg tttgtttcaa gctatttttt cctaagaaaa gaaaaacagc
     4981 aaaaaataat tctaataata caaaaaataa gataaagcta tgcatgaaaa attcttctgg
     5041 aagtacattg atgattggat cagtaacggg atcgaataac cagtcatcgt tgttgaaaaa
     5101 cgtttcatga aaaaggataa aaaagcgatc aaatcctatc atcatgaaaa aaccgaaaac
     5161 aactggcagt aacatgccga tttgaaacgg acgaatcaac cgccaaagcc gatcattctt
     5221 ttgcaaatat ttgataaaca aaatactcgg gatcaaagtg atgaaaaaca cagcataatc
     5281 cactaaaaac aaaattttca cttcataaaa gtgatgggct ccgctagcag aaactgggaa
     5341 atctggcaag ctgaggatgg ttttgaaggg attattgaga taattcatta ggtgatcaaa
     5401 atttttcagt aacgtctctt gatctaaaga agtataatcc aaaatttgca aatgtccgat
     5461 atcaaatacg tatagtggtc gaaagttgat cgtcacacca actgccagac tgatcagtgt
     5521 cagaaatagg ctgaacaatc cagcatattc catccactgc catctcgaat ttttcatatt
     5581 agaagctcca ttcatccagt gattgtttca cataggtagc tgggataggc aacccaggta
     5641 catcttcttc ttttgtaaaa cctgataaaa cgagcaaagt atctatatta ttgcgtatcc
     5701 cagcttggat atctgtttca tagttatctc caaccatgat tacttcttct ttttgcagcc
     5761 ctaatacttc aacggcttta tccataatga tggcttctgg ttttccgatg tagatcggcg
     5821 gcgtttgggt tgctgtctct acaaaagaga tgactgaccc tgctccagga agaaggccgc
     5881 gttcagtagg tatattctta tctgggttcg ttccaatgaa agtagcacct ttttgaatag
     5941 caagtgttgc tttaactact ttttcatagg tcagataatt atctaagcct accactacat
     6001 agtcaggagc ctcttcttcc catgtaaatc cggcagctaa aatcaagtca atcaatcctg
     6061 cttctccgat aacatagact tttttccctt ttccatctgc tttcataaaa tcgattgttg
     6121 ccaaagtagc tgtgtagact gtctctggag ctacatgaat gtcaaactca tctgctagac
     6181 gattagctac tgtttctggt gacttagtcg tgttattggt aacaaacaag aaaggtaatt
     6241 ttcttttttg caattcttcc acaaatcgtt taccggccgg tatgggttgt gtcccacgat
     6301 aaatcgttcc gtctaaatca attaaatatc ctttatagtc cattcatcca ctactcttcc
     6361 ctttttctga tcgtaaatgc tgtttttgtt ttttctactt gtttaggttg ttcttgtttt
     6421 tttacttttt cagaggtttt tgctgactct gtttttcgat ttttaataac cggttttttg
     6481 cgattagatg cgactggtcc ttttttctca tcgatatacg cacgattatg gttttttttc
     6541 ttttttcggc gctgagttgt cttttctttt ttaccgccga ttctctcgat gacaaaatac
     6601 gcacaaccaa aattgcaata ttcgtaaaga tagtcttcca aggaatcgat tcgctgatct
     6661 ggatgcgccc gtcgattatc cgcttggaaa aatcctttta ggcgtagttg ttcataaccc
     6721 caatctccta cgatataatc atatcgggct agtacatcac tgtaacgttc tccaagcttt
     6781 tctgcattaa atccttcacg ataatcggac acaagccgat aatgtctttc acctatcaaa
     6841 aaattactgt catctaacag tgtcactagc tcgcctttga ctttttctgc tttaggctcc
     6901 tcaacgattt cttccaaagc agctgtcagt tcttcggtga ctgttgtttc ctgttcagct
     6961 gatgattttt tcttagcaat ttctgtttta tgctcaacgt tctgctgttc attttgtttt
     7021 gcagacatgc gttcaccacc tatctttttt attatacctt gtttttattt gattgggtag
     7081 tgagctttca agtaatctcc taccacactt cggataaatt cagggaacaa aaattcattt
     7141 tttccagcaa tctcaatcgt tggaaaaaat ggaacaaaca tcaaatgatc tacggtagta
     7201 aaagtataat ttttattcag atcgattggc ttgttcttcc aaaagacttg atggttaata
     7261 gaatcatatg tgattccatt atagaccatc tgcccaaaaa tcttaccgcg aaatcccatt
     7321 cccttcatag gatagttacg taaaaagtta cgattttttt ctatttctaa aactaagcgg
     7381 atcagatcat ttccacccaa tgtgacattt aacaagtgca tcggatgcgg caacgcagtg
     7441 tgaagctgat cctgattgac ccgccctttt ggaatttcag ttaaaaacag accactgttt
     7501 aatattgctg cttccgtctt tcctcgttct ttcaccgcct caaaggctac ttggataaac
     7561 gaatgctcat tgaagatatc tagactcaga gaaaatggca aatctgctac ttctttttct
     7621 tttaataatt catgcccacg ttctagataa ctatttattt cttgttcatc ttctgtaaaa
     7681 gctgtcattg tttcggtagg gatggctttg gctgaatgct taaggatttt tttctcttca
     7741 tcgatggtta aatggacttc accgacatac tgcccgtact ttccagcggc tgctatttgg
     7801 acatcattga ttacgtgacc ttctctgaat aaatgatggg tgtgcgatcc taaaataaca
     7861 tcaattgctg gtatttcttt tgcaatttgg aaatcatcct gaatcccgag atgactcatc
     7921 aaaactaaaa catccacttg tgaacgtaaa tcttcgacta attctggcaa aatatcataa
     7981 ggattccgta tgtcccagcc attcggatta taagtaagcg gaaatggagc agtaaatgca
     8041 attagtccga ttttcgtctg gtgtttcgtt gtaatgattt tatatggttt cgtccatgcc
     8101 ggtggctgga gcgtattttt atcgaataag ttatccagga tgatatcaaa ctcagcatga
     8161 tcgtataaat gattcaactc ttctttggaa tttcctacgc cttcattgtt tcctatcgtc
     8221 gctgcatcat aaccaacttc attcatcagc aagatatttt cctgtccatt cgttgcttct
     8281 gacaatggat gccaacgatc cacaaaatca cctagatcta ctgcaatcgt tgtcgttttt
     8341 tctttctttt cgttttctcg tttacgttga tccaaaaacc ttctgatcct tggccaattt
     8401 tctaaatgag aatgcagatc attcgtatgt aaaatcacta ttttttccat gtaccctctc
     8461 gcctctcttt atctttatca taccataggc agctttttct tccattgaaa caagctctat
     8521 ttcagagttt ttcctgcctt gaagcaaatt gtataagtac aatattcgat aaatcagtct
     8581 ggctaaaaaa tcaggaacat tcatttttac agtactataa aaataaaaaa aacagacccg
     8641 aaagtctgtt gtcgtttcat tataatcaga cacatggcgg aacctgctta gtgctgcttc
     8701 cttccagacc tgacacgctt cacaagccca ccattgtcct agcctttcgg caaagaatag
     8761 tataccttat ttttcattcg ttgaccagtc tttttttaat ttcttttttc gctggcggag
     8821 ctttcggaaa aagtcagtca aaatcatccc acattcgtct tctaaaatgc caccttctac
     8881 atatgcttgg tggttaaacc gctcgtcctc caaaagattc atcaaggtac cggctgttcc
     8941 gccttttgga tcatacgcgc cgaaataaac ttctgctaca cgagacaaaa tcatcgcgcc
     9001 gctgcacata ggacaaggct ctaaggtaac aaaaagtgca gcatcttcca agcgccagct
     9061 tcccactttt tcacaggctt ccttgattgc aagcatttct gcatgtgtag tagcatcttg
     9121 cgtggtttct ctaaggttat atcctcttcc aatcactttt ccatccaata caaccactgc
     9181 tccaatcgga acttcatgaa gcatttctgc tttctttgct tctgccaatg caaggcgcat
     9241 ccatttttct ttttctactg catcaagatt tgtatttacc aattaccctt ccctgccttt
     9301 gttttttctt gttttacttt agcatatgat aaaaaggctg taactaactt ttttttctat
     9361 ggtaaaataa atacaagagg tgaacaagat gaaaatggat aaattacttg ctctttaccc
     9421 acaagcacag aaaaaaaact ctccagcatc agaagcggat atcctttctt ttgcaattga
     9481 tgatgctttt atctggatca aacaagattc attatctcaa caagaaacca gccttttgaa
     9541 agcgttattc cctgtaatca acgatcaaaa aaaacaccca tggtatcact atctttttaa
     9601 agatgcttct tgtgttcaag aaaaaagctt tcgtttgatc cagcttcacg tcgaatcaaa
     9661 aggagaattc ttaaaaaaag aatggcaaga tactattttg gaattatttc gctattctgc
     9721 tgatttcttt ttttatacag acacagatgc gctcttagtc gaacaaataa accgtgatta
     9781 tcttgatgct actgaaatca acggtatttt tctatcttta gatgctgatt ttgatacgac
     9841 aacgtctgta ttcgttggtt ctttccattc acctggcacc gacctcgtcc ctttgtttgc
     9901 tgaagaaaga aaaatttttt taacagagca aaacaatctt tatactcaca gccgtacttt
     9961 ttctatgcaa gatgtggctt tacattacta tacaaaagat actgtaaaag atagtaagtt
    10021 gatcaaaagt tacatagaac tgatcaaaca aaatgaaatg gaagtgatca ttcaagaatt
    10081 atggaatgaa ttaggcaatg tcagctctgc tgcaaaaaca ctgtttcttc atcgtaatac
    10141 tctaaaatat cgaatcgaaa aatttcaaga acagtctggt ttcaatctaa aaaaagccaa
    10201 cgatttactg ttttgctatc ttttattgct tcatgaacat aattaaagat agattaaagg
    10261 ggttgtgaca ataattttgt cacaacccct tatttcgaat gaatagtgtt caaaagctag
    10321 tttctcttac atcatttttt caacaaaatg cattagccgg tcttttacat cttcggttga
    10381 atctttgatt gaatcaccat aaacagagat tttctttttt cctgatttga tttttgctaa
    10441 cattcccatc aaagaatcca agtcactatc tgaaagacca tctacgattt ctagtaattt
    10501 ttcatttcca tcaaatttgt catagacgaa tttttttact ttcgtccgag tagtcatatg
    10561 atggatcttt tccattactt ttcccgatac aacgactgct gtcgctacac tggcagcggc
    10621 tgctacgctt aatccgattg ttacttttgt tgatgttttc ataagtatca gctccttttt
    10681 atctatctcc atcatagcat agacaaaaaa ataaacgaac taatccactc agtgaaatct
    10741 caatccttta gggaaaaagt tctttactgt tccttttact tgtttcccaa atccgacagg
    10801 tatcttatct aatactagca aaacccatcc ttgattccca tcacgttgaa atgtttctcc
    10861 tgctgtgtaa gattgccatt ccttttgagt gatcggcaag caaggtatat tctctatctt
    10921 ttttgtagca agcgctaatg catagctagg ttcaaatcga ttctttttga aatctcctaa
    10981 atgcaaacct gtacgtacga cttttaaacc atcgagagaa ggggctaact caggaacttc
    11041 ccaaagatgg tcgttgaaca ctaaaagtct tccagtagct tcataatgaa aatcatttga
    11101 aaactccgtc cagagttttt cctgctcttt tgtcatttgc actttacttt tttttcgtgt
    11161 cttcttttct ttatgcatct gattttgtcc atgaaaagtc agctttgcaa caaaatgtcc
    11221 ttcaccctga tctttatgag gccatatacg tattgttttt tccaaaccag ctacgcttcc
    11281 ccattcagaa cgtcctgaac taacggattg agtcaaagga atctcctcaa tcgttactgg
    11341 ataattttct acaagccagc taatgatctc ttcattttct tctggtgcaa acgtacaagt
    11401 cgaataaatc agttgtcctt tattttttag catttttatt gctgaagaca aaatctcttg
    11461 ctgacgtttt tgacagtata gcggagattc ttctgtccac tcttttattg catttggatc
    11521 ttttcggaac attccttctc ctgaacaagg agcatcaacc acgatccgat caaaaaagcc
    11581 cgaaaaatga gggacaagtt ctgcgggtgc atgatttgtc actattgcgt tcgaaactcc
    11641 ccatcgttct atattttctg ataaaatctt cgcacgtttc ggaaagatct cattcgtcac
    11701 taataaccct ttccccttca tttgagcagc taattgggtt gatttaccac cgggagccgc
    11761 acacaaatcc aaaacttttt caccgggttt tgctgcagca gctgttccaa cgatcattgc
    11821 acttggttct tggctatatt catacccagc ttgatggagg aaagactttc cattgacagt
    11881 gccaagaaat ccctcattgc tgtagggagc gggttgtaat tcttcgctat ggtaagtttg
    11941 gaccatgtcc aatcctgccg gttttagtgg attccaccga aatccttttt tcacgcttcc
    12001 ttgttcaagc gcagaaaaaa aatcggatgc ttcttcgcct aaaagaagac gatatttttt
    12061 gataaattgc tgtggtaacg ttgtcgcttc ctccttcatt ccaatgtttc gttagacatt
    12121 ttacaatctt ttttacgaaa aataaaggtg gctgatctac tttttcatgt tgctgcctaa
    12181 ggtgactgtt cctttaagat attttccaag tattcatccg tcacctcgtt tttatcccaa
    12241 acagcgttca tcatttcaag aaaatcttga gaagaatcat ctgagcgcaa acttcccaat
    12301 gcattaagcc ataccaattc aagcgacttt tcttctttga tcttcgtgtg acctttgaca
    12361 tatgagaaaa atggccgctt aaatagcgaa tccatgtcta aatcagattt tgcaatgatt
    12421 tcacgaatac tttcatggat agaaaaaaaa tctttcaata agtagacaat gcttaaaaca
    12481 tcatcggaac tgcattcagc taagtagttt tcaaaataaa cagtgatttc ttctaatatc
    12541 ttctctttta acccgctgat tgatttgaaa tgtgtataaa tcgggtatgt agaacaaccg
    12601 cagaactctg ctaactctct tgcagtaatt gacttcattc catattcttc cacgtatacc
    12661 atacttttga acagcaaata ttctttacta taatttgtta ctctccccat cattcttacc
    12721 tccgtctctt ttcatctacc cataaataaa taacataaat aattctaaaa atattattga
    12781 taattatcaa aacatattta gttatatcca ttaaaaatca atttttccgc cttaaaaaca
    12841 agaatatctt gacaaaatac cctaggaaat aaacaataga ataaacaagg taacaaaaaa
    12901 attaaataac gttatataaa aaagaaggcg acactctgtg agaataacac agactgaaat
    12961 gactttccac tcacagtttt tgtctaacta tatacaaaaa cagaataaaa aggaggtatt
    13021 tatgctaatt gaagcaagaa aaaaagagtt acttgttcta caaatggtca ttcaaaaaaa
    13081 taattgttct ttacaagaat tatccaatga cttacatatt ccaaaacgga caatcaaaga
    13141 actgatccga aaaataaatg tatcactcaa gcaattttta ttgattgatg aatttattta
    13201 ttctaatcat aaaggagaga tccaaaccaa agaaaccgat caaactaaaa agttagctgt
    13261 tttttctaag ttaaaattat gctacctaaa agaatccaat cgttttaact atttgatgtt
    13321 actaatcaat tatccacaaa ctgctgtacc aaaaaaatat ttacttgaac aactttatat
    13381 atcgccctcc tatctcgaaa aactgacaaa acagctcaat cattccttaa aaaaattcca
    13441 tttacggatc ctatctgtaa aaaattgctg tactcttgaa ggaaatgagt tatctatccg
    13501 tctctatctt tacttttttc tttcagatac atttggaggt aacgattggc cattttcctc
    13561 acttgaatta aatgcactaa aaatgaacag tacagatgag caaatagaaa aaatttcaaa
    13621 acaagaaaaa aatatctact tgctgttaac tttattcata ttacgaaaca aacaacaggc
    13681 atattttcca aaaacttctt ctgaaatcac tgaattgatg gacttattgc agcatacaca
    13741 tgattattca gaatacttta cttctttttc agtgagtcgc ccttgtgaag agacagaaac
    13801 agagagagcc tactttaatt attttttcta ttgttttttt ccaaatcaaa tctcttttcg
    13861 acaaaaacag gagattggtt ttttattttc cacaagcaaa aaccttattt gtcgacaagt
    13921 cggtcaattg atgacttact taactcaaca gtttcctctc aaccatttag aaaataaaat
    13981 accaatttat ttttattttc ttgtgttggc agttgttttt ttcgaactgt tgggtgaatc
    14041 cagcagtagt ttttctacac tttgctttcc agaagccacg tccaatcatt ctagttcttt
    14101 tatacaggaa aagaaattaa gagaaaaaat cgatacaatt ttttcaaaaa atggggaaag
    14161 aaaccaaatc agtcaatacc ttagtcaatt gatccaacac ttactacaaa cagaaacgaa
    14221 agagcagtta ctcatccatt tgcagataac caaacagttt acaggaaatt atcatcttca
    14281 aagccatttg cagcagttat ttcgcaaaga tgctgttaaa attaccgcat attcagaaca
    14341 tgctgatttg atcattacag atcagcatga gaaaatttca gatgaaacgg agactttcta
    14401 tctggataca acgcacaata cagtgttatt tggcaagtta ataaaagcgg ttcatgaact
    14461 gtatatgaaa aaaggttatg agaacaaaac aaagaggatg tgacaaaatt cttgtcacat
    14521 cctcttattc caaataaatg gtattcaatc agctaactct cggtattagc tcagatcaaa
    14581 gcgctgattt cacaacttct ttattttaat ctcttcggtt gccgccgaac aataagatca
    14641 agcgcaacag ctgcaggaat gtcgaaagcg ctgctgcaac ataagtcagt gctgctgcaa
    14701 ataatacgtg tcttgccatc ggtacttctt cttccgtcag tagtccgcct tcactcaaaa
    14761 tttggattgc tcgccgagac gcgttaaatt cgactggtaa tgtcaccaat tggaaaagta
    14821 atgctaaaga aaaagcgaaa atcccgatat tgattaacgt agagttccag ctaagcaata
    14881 cacctaccat aatcaagggg aacgaaatca tcgaaccaaa gttagctgct ggaacaagtg
    14941 ctgcacgaat cttcaatggg acataacccg aagcatcttg taccgcatgt ccgcattcat
    15001 gagctgctac acctatcgca gcaactgaag tagactgtgc agttgcttga gacaaactca
    15061 acatcttatt acctgaattg tagttatctg tgagatctcc ggcaatttgt tgaacaccga
    15121 cattatttat ctgttgactt tgtaatatat attgtgctgc ttgtgtacca gtcacattgt
    15181 ttttgcttct cacttgatcg tattttcgga aagtactatt gacgtacgct gacgcaattc
    15241 cggaaataac taatccaaga atgaccaaaa gaaatgtcgg atctaaaaaa ccatacattc
    15301 cataaccata cattttcgtt tcactccttt tcgtttactt tattttatca ttagtagtag
    15361 gaaaagaatg tgaaaagacc ttgaatattc tttaattctt tttcacaaat tccgatttca
    15421 gtttcatcgg tccaaatcct tctaccttgc aatcgatatt atgatcgcct tctactaaac
    15481 ggatgttctt gacttttgtt ccttgtttaa tggcacctga cgcacctttt actttcaagt
    15541 ctttaatcac tgtcacgcta tcgccctcta acagacggtt tccatttgca tctaatacca
    15601 ctaatccgtc ttctatgaca gtttcttgtt cttctttgtt ccattcgttc ccgcattctg
    15661 ggcaaatcaa caagcctcga tcttcatatg tgtactctga gccacattct gggcaatttg
    15721 gtaatgtcat cttctttctc ctttaaaatc tttagtgagc actattgtaa cggaaaaaga
    15781 agatcttgaa aagatacatt tgtgattttt actacaaaag gcacgttttc gaacgaagta
    15841 tcattctgtt tttctgctct tatacgattg gcatatatct tggatctctt tatagatttc
    15901 ctctacttct gctaaatctt ttgcattcgc accacttgct aatggatggc ctcctccatg
    15961 atggcgttta gccaattcat tgatgatcgg ccccttagaa cgtaaacgta cgcggtaata
    16021 ccctgaaggc tgctgaacaa aaatccccca agccagcact tcgtcaatca ctccaggaag
    16081 tgaaacgatc gaagctgtct ctgaatcatc gattccatat ttatcaagaa tttcttgcgg
    16141 aaggattatt cttcctgcac cattttcatc cacctggata ttttgataaa gataaccgga
    16201 aagtttagcg actttcatcg gcatttgttc aatctctctg ttcaaagcac ttgcatcaaa
    16261 tggataattt ctcaatatcg aagcaatctc taatgtacgg gacgtcgtgg agggatacaa
    16321 aaagcgccct gtatctccga cgattcctgc ataaagtaac cgtgcagcct taacgttcat
    16381 ctttaaagat tcaggaaaca tcaaagcaaa ttctgcaatc atctcactac agctacttgc
    16441 ttttgtattt acccacacaa gatctccata agggtcatca ttgggatgat ggtcgatttt
    16501 gatcagtttt tctgccaact gatatctttg atcactgatt ctgggtgaat tagctgtatc
    16561 agtcacgatg actagcgctc cttggtagaa gacatcttca acttcttgca tttctgctaa
    16621 aaagcgaagc ccttcaatcg tttcacctac ttgacgtatt tctttttctg ggaaactttc
    16681 ccgtaatagt tcggctaatc ctacttgtga tcctaatgca tcaggatcag ggcgcaaatg
    16741 cctgtggata atgattttat cgtatttttt tattgtatct actatttctt gctgtactgt
    16801 catttcactc ctgctttcta agaacgttcc attacttgac aaacaacgat tgctttggaa
    16861 acgatggtgt tttcaataaa cacttcgata tccagtttag cggaacgtct gccgatttcc
    16921 aatacacgtg gacgaatgtc taattcgctt tccaattgga tcagccgcaa ataatgtagg
    16981 ttcacttgtt caatcaagat atttcgtttt tggttcatca ccattgtttt ttgtgcgaca
    17041 tcagaaatga tttcgctaag tacgccaaaa gaaatggttc caacgccatt gaccatttgt
    17101 ggtgctacta cgaatttgaa cttagggttt tccaaacgat ttccttcacg gtcagtatca
    17161 atcgtatgga tatttccaga tatctgatcc gaaatcgtat ctgcaatctg cggttgtcgc
    17221 tggacaagct gcatcgcttt cattacatct tgccgggtaa tcaagccttc caatgtcaag
    17281 tcatcggaaa cgaccggcat gacttctagc ccatcccaga tcatttgatg gctaacagag
    17341 gcaatactca ttgttttctt tacactgatt ggttctttcg tcatcacccg atcgatgatc
    17401 tggtttggcg atttccctaa aacatctttt gccgtaacaa tccccatcaa acgatgatgg
    17461 cggttgacga ctggaaaacg cgaatgctgc gtttcttctg acaaacgctg ataatcagaa
    17521 atcgtatctg tctgctgcaa ataatgagtc ttttcagctg gcatatagat atcactgaca
    17581 agcatgatat cttttttgat caattggtcg cttaacgctc ggttgatcat ggttgcgact
    17641 gtaaatgtat cataagaggt gcgtaagatc ggcatttcaa gatcatcagc tagctttgca
    17701 atctcagcag tcgtattgaa tcctcctgtg atcaatactg cggcgccatc ttccaatgct
    17761 aatttttgga cttccgcccg gttgccgacg atcattagtg atcctggcgt aatatagcgt
    17821 tccatggcat gtttagtcat cgcgccgatg acgaatttat tcaagacctt gtctaatcct
    17881 gccgccccgc ctaaaacgtc cccttcaatg atcctgacga cctcgccaaa tgtcaaacgt
    17941 tcaatatgtt tttttaattt gcgttcgata cggatggtcc ctactcgttg aattgttgaa
    18001 actagtccga cattttctgc atctttgatt gcacggtacg ctgttccttc actgacattc
    18061 aattcttttg cgatgcttct tacagaaatt cgattgccaa caggtaaact ttcaatatat
    18121 tctaaaatca aatcatgttt tgtcgccatt ttctgcctac acttccagcg tttccgagac
    18181 gctcattatt tttccttcac tatcttccag taactctaca aaagattcgg gatcttgttc
    18241 aatgacaggg aaagtattgt aatggattgg aactactttc ttggcacgaa ttgtttgcgc
    18301 agcctttgct gcatcttctg gccccatcgt atagttatcg ccaatcggca agaaagcgac
    18361 atcaatatcg aattcttctg caagcaatcc tagatcactg aaataagcag tatcccctgc
    18421 atgataaatc gtttttcctt ctgcttgaat aataattccg ctaggctcgc ccatatactg
    18481 aacgataccg tctacttcat agcttgaact atgctgtgca tgtacgaatt ttaccacgcc
    18541 gaatggaaac gcatgttttc caccgatatt cataccgaat gaatctactc ctctgctgtt
    18601 cgcataatca gcaatctcaa caatactgat aattgtggct tgattttctt ttgcaatagg
    18661 aatcatatct cctatgtggt cactatgacc atgagtaatc agcaaccaat ctgtctttac
    18721 ttcttctgca gttaagtctg tcaatggatt tcctgtaata aacgggtcaa tcatcacgcg
    18781 ttggccattt tccatttcaa ttgttaaaca ggaatgtcca tgatacgtaa ttttcatatt
    18841 ttacacctcg cgttttctct gtatcttttt tattaaaaac gatttcatca cttgcacatc
    18901 aatgaaaaaa tatagctgct aaatatattt tcattggatt gatagtacag tatgtacaaa
    18961 gcaattgtaa cagataatac aggatgcacc aagtaccaag cagatataat ctcaagtttg
    19021 aggtctctgc tctgcttagc ttctcttctc gtcccttaac taattaaatc agcgtaaata
    19081 ggatggacga tcttttctaa atcggctact tttatccgaa ggcttctccc gatttcaccg
    19141 cttgacacaa ttacttcttc tttttctttt aaagaactgt ctgctaaaaa acaataatca
    19201 ggatgtgcga gttttattcc aataggggtg tttgctccgt ggggatatcc tgtatgcatt
    19261 aatacaaaat ccattccagg aaaaccaact ttacgatctt tcgtcacttg tctcgttttt
    19321 ttgtaatcta agtgatcgtt caaaggaatc aatgcgatga tcaccccagt tttgtttcct
    19381 ttcactacga gagttttaca tatcaaagct ggatcaatcc ctcttttttg tagttcttct
    19441 gtgaaagatt cttctaccac atgactaaaa tcaagtggtt gatagctgat cttttgttct
    19501 tctaaataac gttcgacttt tgtttgactc atcattgatt cactcccttt attctatcgt
    19561 ttattataaa gcgagggatg ctgtattcaa aaattatttg tttttcgcaa aaaaagagca
    19621 agacgagcac tctatagaga ggttcatctt actctttttg tttatttttt atttcgacgt
    19681 tgagtagctt ccataatgac tggcaagatc actgggcggc gttttgtttg ttcaaataag
    19741 taacggccta attgatctcg gatgtcttgc tttaatttgc tccactcaaa atcattgctt
    19801 tctaaatgtt tctcaacgat tgtttcaatc atattgctgc tttctttcat cagatcacgg
    19861 ctagctttta cgtaaacgaa tccccgtgaa gtaatttgag gttttgaaat gattttcttt
    19921 tctcgccgac tgatagtgac aaccgctacg aaaatcccgt cttctgacaa gatttttcga
    19981 tcacgtaaaa caatgtttcc gatatcacct atgcctaatc catcaatcat tacattttct
    20041 gcacttgtag ttcctgcaac actcatacgc ttgttcttat attccagcac gtctccgcgt
    20101 ccagtaatat agatattttt gtatggcatc cctactgcat gagccaaatc tgcatgagca
    20161 gctaattcac gatactctcc ttgaactggc acaaaatatg ttggtttcat caaattgatc
    20221 attaattgca agtcattagg attggcatgg ccagaaacgc gcatattctc agagatcaac
    20281 ttcactgttc caccagctcg ataaatgata tcttccgttt tcgccacgat ggtttccatc
    20341 gcgatgcttg gcgtagtagt gatataaacc aaatctcctt cttcaatctt gacattacgg
    20401 tgtgtaccgt ttgccatttt ttgcagagac ttgatgggtt cacccattcg gccagtttct
    20461 aaaatgatca gttcttctgg atcatagttt ttcatgtctt tcaacgtaac aagcagatct
    20521 tcacttggta attgaagttt ttctaaacgc atcgctgtgc gaataattcg ttcgaaatct
    20581 tgaccagtca agacaacttt tcgttgtgct ttttctgctg catccaatac ttgttgcact
    20641 cgttgcaaat tacttgctac acaagcgacg atgatacgcc cttcccaata tttgatcgta
    20701 tcaaatactt catctgctat ttgggcttca gaagctacag gctgaggatt ttctgcattt
    20761 gccgattcac ttagtaaggc taagactcct tctttgccga tttccgccaa tcgtgcataa
    20821 tctgtttgat acattgggat agccgtttgg tcaaatttaa aatctcccgt ataaacgata
    20881 ctaccttctt ttgttttcag attgatcccc actgaatctg gtatcgtatg agtggtacgg
    20941 aaaaagctca ctactgtttc accaaagtct atttctgtat gctcatctac cacatggaaa
    21001 tccttaaatc ctttggctgc ttcattacga ctgacattca attttgctaa ctcgatcgtc
    21061 aactctgtcc cgaatactgg tacagaaatt tttgacaaca agtaaggaag tgccccgatc
    21121 gcatctgcat gtccatgtgt taaaaagaca ccagctacac gatcaatgtt ttcttctaaa
    21181 tacgtaaaat cagggattac gacgtcgatc cccaacaact cattttcagg atattttagc
    21241 ccacaatcta aaataaaaat atcctcgccc acttctgcga catacatgtt ttttccattt
    21301 tcacgaacgc cgcctaatgg gataatttta atggtactca caaacttcac ctcttcttat
    21361 gacatccaag tttaaagatg tcgattttct tctttatcta aatatatgag ccattccaat
    21421 gaagcatatg caaaatcact atttctcaac ttatggagaa tcagcaggaa aattaccagc
    21481 acatccgcgt tctgacagtt ggatgggcat tttattttgg atatacttca ttaacaaaat
    21541 ggatcttttg cgaaacgcta tagccagaat acttatataa gtattcagct gttccccatt
    21601 attatacaac aaataaacta aatcgctagt atcagcaatt gttagaacaa ctatgcacgt
    21661 aaaaatccct ctgtagcatc taggatttct tttgctattc ctctttcatt tcttcttcgt
    21721 cggtttgaaa catacttttt tcattttacc acattttttg caataactat agtgactttt
    21781 tatatataca gaacctcatg ttgatggtgt gcaaacagca taagatttaa gctagcttta
    21841 agataggttg tctattatca aatgcatcta ctaggaggga tgcaaaatat gaattttatg
    21901 aaacgtgcat ggaaaagtac aaaagtaaaa tggggacgtt cattgttatt gtttgccgtg
    21961 ttcacagcca ttcttatttt tgtgctagct ggcctcacga ttcgaagcgc tgcagaagaa
    22021 gcagcgaatc aagcacaaaa agaagttgga gcaacagtga ctttaagtgc caatcgagaa
    22081 gcttcattta aaaaacagga acaaacttct tcaagcggtt ctaccactga agaacgtcca
    22141 gatccaggca gtttttctct tacaccagtt tccttaacgg acgcggaaaa aatagctgaa
    22201 ttagataatg taaagagtta ttcctttgaa agttccgcct cagctatggc aaaagatgga
    22261 ataactgcca tcactagttc tgattcaagt gaagacagtt cagaaactac tgatgcaggc
    22321 ggtgaacctg ctggaggaat gggcgggaat ccgcaaatga ctcaagcaga ctttcaaatc
    22381 agtggtgtgt cagcaactgc acaaaatagt aatttttctg atggaacagc aaaaatcacg
    22441 gatggtgaag gaatagatga cagcgacaaa ggcacaaaca atgtagtcat tgattctact
    22501 ctagcagaaa caaatgacct ggcagtcgga gatactttca caatcacgag tactgaagat
    22561 gaagatacca cttatgaaat gacgatcaaa ggaatttatg aatccagcga aacaagcggc
    22621 agtatgggta tgaaattcaa cttcatgaat ccgtcgaata cactttacac ttcttacact
    22681 tttgcaaatg aactaaatgg gacatctgac gataacacga tagattctgc tatttacact
    22741 ctatctgatc cagataaaat ggatgagttt ctcaaagaag ctgagaagct gatcgacaca
    22801 gatacattta gcttacaatc aaatgattcc atgtatcagt caatgttgga acctttaaac
    22861 aacgtggcaa gtttttctaa aaatgttgtt ttactagtgg ctgtagccgg tattatcata
    22921 cttactctga tcattatgat taccattcgg gagcgtcggc atgagttagg cgtcttgcta
    22981 tctttaggag aatccagaag taaaatcatt ctccaattgt ttaccgaagt ggctatttgt
    23041 atgattcttg cattaggagt tgcttcgctt agcggaaacg tcgtcgcgaa tgccgtggga
    23101 cagcagctac ttgaccaaca gacagaaacc acgacacaaa accagcaagc tcctggcggt
    23161 ggacaaatgc caggtaacag acaagaacaa ggcggtcaac gcgatggtca acaaggaacc
    23221 acgaataatc catttgctgt ttctgatcaa gtcagcgaat tggaaatcaa tgtcaaacct
    23281 gcacaattgg gactattagc cggagtagca tttggaatca gtctgttttc tgtcttttta
    23341 gcttctatag ggatattaag attaaaccca agaaaaatcc tattaaacta aaggaggaat
    23401 ttgatgttac ggacagaaca attgggattt tggtatcaag atccgcaaga tgcgctttat
    23461 aaagatgtag aactgaattt cgaagctgga aaaatgtacg ctattttagg agcaagtggt
    23521 tctggaaaaa cgacttttct ttcgcttatt tctggactag atgcaccaaa agaaggaaag
    23581 gtatactatc aagatcgttc actgaacaaa atcgggttaa gaagttatcg taaaaatgat
    23641 gtctcgatta ttttccaagc ttacaacttg cttccttatt tatcggctct agacaacgtc
    23701 atagcagcaa tggaaatcac taagaccaag caagagaatt atcgacaagt tgctttagat
    23761 cgactggctc gtgtaggaat tgatgaaata ttagcaaaaa aacaggtgac caaactttcg
    23821 ggaggtcagc agcagcgagt cgctatcgtt cgtgctatct gctgtgaaca tcaactaatc
    23881 gtagcggatg agcctactgg aaatctagat gaaacaactt cacaagatat cgtcaaactt
    23941 ttccaagaaa tcgcccatga acaaaatcgc tgtattatca tcgtgactca tgagattgaa
    24001 gtagcaaaaa gctgtgatga agtctttgaa ctaaaaaata aaaaatttca aaaaatcgaa
    24061 gtttaaaaaa caggataatg atcaaataaa aaatccgaac catatctgtc tcgcagatat
    24121 ggttcggatt ttttatttgc ttgattcaat tagtaataag tggtttttat tttttttcgt
    24181 cttttcgaga aaacttgtct ttgacttcgt cgcctaaatt tcgagctttt tctttgatgt
    24241 cagcacctag tgattgtgct ttcccttctg tttctttgct cttgtcgtct gttgctttgc
    24301 cgtatgcttc ttttccttca ccgactactt tatctttcat atctttagaa cgtcctttta
    24361 aatctgccat tgtgcttcct cctcttagtt tgtttattga tctaccttca gggtaacatc
    24421 aacaacagat acagacaaac agaacgctcg ttttctaaaa aagatagtta gagctgttga
    24481 ttaaaaactt ttttcgaaag tcccccatac tttgacttct ttttcttgga ccattatttc
    24541 tcctttagcg ataactgtat caatatcaag cgtttcttta tccaagatac acagatctgc
    24601 atcagcacca atttcgattt ttcctttttt atccaatttc aatatacgtg ctggattact
    24661 ggttatagct cgtaaggcga tttccaaagg gatactttct ttttgcacag cttctttgat
    24721 ccctactagc aatgccttgg cacttcctac tcctaaccct aggaaatgat tgttttcatc
    24781 aaaataaggc aagcttcctt gtccatctga ggtcatcgtg aaattatcta aagaaacatc
    24841 ttcctcgatc aatcgtttca gtgctttgct gaagcgaact tcaccatctg tcttctccca
    24901 aaaatcagga tcttcgctag cagtgaagtc aatcgtgcca ccacgtttgg caaatgccac
    24961 gcaagcttca aataattctg gtgtgcgatt tgcatgagta ggcaaaaatt gtgtgatcgg
    25021 aatttctgtt tcttctacga ttcgtgtcaa tagctctagc tttctttttc ctccgcctaa
    25081 gtggacattg atgatcccag cttttccgga taacatgcct cctacacgag catctgctac
    25141 tgcacgagcg aactcttcaa aacttggctg agaagaacgg tgatcggata ctgcgatttc
    25201 tccgattccg ataattttat caattgtcaa aaagtctttg atgatagaat ctgttactgt
    25261 ttttaccggc aatcggtacg aaccttcgta tacataagtg gagattcctt ctgcttccag
    25321 acctttcgct ttgctgatca acgcagtcat atctctacct tctccgtctg ttcccaaaca
    25381 accgacaact gtcgttacac cagctgtagt caattggctc aatgtgactt ctggcgttcg
    25441 attttgataa ccgccttctc ctcctccacc taaaatatgg aaatgacagt caatgaaacc
    25501 cggggttagt acttttccct cacctgaaag ttcttctact tccactcctt cgtagccgcc
    25561 ttctagctgt tcttctacag ccaaaatctt cccaccggca atcagtacat ccatttttcc
    25621 taagtaatct ggtgcaaaca cttcaatttg tcgaatgatt ttcatacatt tttcctcttt
    25681 ctttaagtat aactgatgat aggatcttaa aaaataatcc aaacgatagg atctttactc
    25741 ctttgatttt accgtaaaat gacggttctt ggagtcctta tctactgttt ggattacttt
    25801 tttatttaca ggtctccagt actactgcag acctattgca atggcaatca tgatgaaaat
    25861 agttcctaaa acaaacagga atccttgcat cttgatttgg aatcttgccc attttgccca
    25921 ttcgatccgt gcaacaccta gcacaccaat caagctggct gatacgggtg taaaagcgtc
    25981 cataaaacct gaaccaagct gataagcaag aactgctact tgtctggata cacctactaa
    26041 atctgccagt ggagccatga ttggcatagt caaagctgct tgtcctgaat ttgatgtaac
    26101 aaccaagttg aacaaacttt ggaagatgta catcgcccaa gcaccaatga cagctggaac
    26161 accggtcaac gccgtcccga tcccatgcaa aatcgtattc aaagctgaag gaacagatgc
    26221 atcagatcct cccaagacaa gaagaatccc tttggccata cctactacga ttgctgtacc
    26281 agctaaatca gctgcaccag attggaaaga agaagcgatg tcattgactt tcattccatc
    26341 taatttgaaa agaacagcaa tgattccagc aactaatccc atcacaaaga attgagaagc
    26401 gatttctgga atgtaatagc ctttttgagt cacgccccaa acgatccaga caaggacaac
    26461 taacatctct aataagatca atttatgccc aagcatgaat tttttatttt catcagatgt
    26521 ctttttgata tgagaacgga aataatcatc tgatttgtaa gtcaacgaac tttctggttt
    26581 tttacggatt ttttctgcat atatcatcat ataaccagcg gctaatgcag taacaactac
    26641 ccacataatc aatcggaatg tcgcaccaga caacacgggg attccagcaa tcccttgagc
    26701 caccgctacg ctaaacgggc tcatccaaga ggtcgcattt ccgacttgag atgcgacata
    26761 agtcacggtt actgctacga tcgagtcata tcctaacgca atgacaaatg gaaccatcac
    26821 cattgagaat ggaattacct cttctgccat cccgaatgta gcgccaccga atgaaaaagc
    26881 aaagaataat agcggtaaag ctaaacgctc cagtccctta gttttactga taaacgcata
    26941 gatacctgcg tcgatcgctc cggtacgcat aataatacca aaagcacctc caacaacaag
    27001 gatcaatgca gcgatcccta cagcagatcc atacttatct ccagatacta gtccttcaaa
    27061 aacaaaattt aagaaaccaa agccgccaaa atcatctgtt ccccatattt tggctgtttt
    27121 atgcaatttt ttagaagtat catagatatt ttcgccgtac tgatcgtaaa gcacatcatc
    27181 tgtcaaggag atttcatcta gtttttcctg cgtaagattt ttttctccgt cagcaatgac
    27241 tttttccaat cctttttccg gaacatccag tttttcacgt tctgctggat gatcttgcag
    27301 ttcttctaat tgatcaaaca catacgactt atccagctcg taagcataac ggaaggaatc
    27361 ttgacgtaaa acagtacgag tacttgtttc gccatttgca tctttgtatt caatatcttg
    27421 cgtgctgaac tttcctgctg gaacgacaaa agtcagtatc catgcaaaga tgactacacc
    27481 aaaaataatg acatacgtat ggggtgtcga taatttagtg aagtcgcgtt tcggttttcc
    27541 tgaagaattt gttttcttca aatttatttc ttcctttctt ttttcagtaa ttttgatgaa
    27601 taaaaaatgg ataatcaaat gaattataca gtaaaaatga catttccaca tgaataattt
    27661 attagaaaat cacttttttc tattttgttt tttttctcct atgtatgatt atttttttct
    27721 ctttccattt atattaagta ttttatttct ctgtttttcc ttaaaattct ttttttattt
    27781 ttagattaga gaaaatctcg tcctgttttt ttcattttac aatcattgaa aaattgaatt
    27841 tcattgcaaa aaaaataata aacacttata aatatccatt atctatcctt caatttttgt
    27901 gtattttatt tctattagaa aaaggtatcc tgttggacaa ttttgttata tcaggtaaac
    27961 ttcattgcaa taatgataac aaatgtacta taattacttt gtaaagagtt ttggggaaga
    28021 ctctttcatc aacgtgtatt aagagacaag aaagaatcca tatggattct ttcttgtctc
    28081 tttttccact actttttatt tttctgacac tacatattct tataactcat ttctcataac
    28141 tgtgaaacaa cttataaaaa taacaaactt taaacaaaac aagcttaaaa tcaaagatga
    28201 tccatcttaa aataactaaa acaaaaaaag tagtcgttgt taatcctcat taataatcgt
    28261 tttctttttt tcaaacgctc catttttatg tggaacatta tttttttaag gaactttgtc
    28321 aacatgtgga taactatttt ccacttgtgt cctggactag ctgttttgct gtaaaataca
    28381 aaacttgctg cagcaaaaag atcgttgcaa gagaggctgt tccgcagatc gctggatcta
    28441 gatttggcaa agtcaagact gcatcatgta aattggcgtg gttgtccaaa accaaatcag
    28501 caaattcaaa taatcgcaaa ccactgctat gttgcgattt gatacttcgt gacaaatcaa
    28561 atccagtaac aatgattaat ggatgaccat tttctttgat ccactgagct agttcgatga
    28621 ttgccgggtt tcttccttca ttcgaaagaa gaagaaaaat gtcttctgat ttgacagaaa
    28681 gctgatcaat aattgcctgt cctgcacctt ctagcgtttc atagacacct ccggctggat
    28741 tttcaatcaa tatacttggt acaagatccg gggtttgatc ccaaaattca aatgctacac
    28801 cacttagtgt gcggctagca tatatctgca atctaccacc ttgattaatt tgtttcgcga
    28861 tccaagtgcc agcttgaagc atcagcggct cttctatcct taatttctct tccaattggt
    28921 gataatagtc aaaataacat aaactcattt atctctcccg cctagctata cttgacatga
    28981 atagaaacag ctgcctaatc taaggaagta cataaaaaaa cagtagttag acagtaacac
    29041 atgtggtctt tgctgtttca aacacaaaaa aggcattgaa cgaatacgcc caataccttg
    29101 acatagcaaa taaaacaacg tgcagaccat ggaaaatatc tacatagggg tagaattttc
    29161 accctagatt aggtacaata aattaggtcg atgcactgca ttgactatgg caaaatgatc
    29221 ggtcagggtg tatgtgtgtg actggtcatt ccctgattct tagcgccaac taagggtcag
    29281 ggagcctttt tttattcagc tgtttctatc tgaatttatt gtaagtaatc tcttatccaa
    29341 gtgcaagcaa gaaaatacaa aaaaacattg gtatgattta tatatatata aataacataa
    29401 aaaaaggaat ggcttatccc gatacaacaa gcattccttt aaaaaagatt cttttatata
    29461 agtgaaaaaa gcttttttcc accaattaaa taaatctctc atctcaatag tttatccatt
    29521 attttatctt tttttgcgta tacctactaa atattaccgt cttcttctcg ttcttctact
    29581 ttgttcgaga gaatctgtac tagaaaaagt agttgtatgt ctaccttttc tgcctatccg
    29641 agactttctt ttcatatatg ggatataaat gattagatac agtacagcaa aaaataaagc
    29701 aaatacgcaa gcttcccaac tacctaacgc caattcaacc atcaaggtag caaccccaac
    29761 ggatgctgca taccagataa aaatcagaaa cgtttctttt tttctgacca tgcgaaacat
    29821 gataaataga ctaataagca atagtggcaa cacaaatatc caattgcttc cttccatcag
    29881 ccacttgagt atatcaagca gcgactgtgc aacagcgact aattttccca tagtgaacac
    29941 acaccttttt ttataattaa aaaattcgct tttttattct actatgaatc ttctggcttg
    30001 gctttcattt ctcttatgta atcattttct tttatacaac ttaaaaaaaa attaaaccat
    30061 tagcataata ttttctgaat ctattcacga aagtcttttt ctatctttcg ttttccacga
    30121 ctcaactgat ctagagtcaa aaaactaaaa cgacagttgc gcaaatgacg cacaagctgc
    30181 cgctttaata acaaatagcc tttcattctc agcaggccac ttatttccag ttaactttct
    30241 gttcttagct ttttactcaa ctggataata tatgcactta atgaagtccc aatttccgaa
    30301 tgttgaagtc catattcaat atttgtcttc atatatccta acttatcgcc tacgtcgtat
    30361 ctttttcctt taaactctct cgcatagacc gcctctgtct ggttaagagt ctgaagtgca
    30421 tccgttagct gtatctcgtt tcctgctcct ggttcttgag tttctaatat ctcaaatatt
    30481 ttaggagtca gtagataacg tccgataatg gctaaattac ttggtgcttt tcccatttca
    30541 ggtttttcta caaacccttt tactctgcaa cgaccctttt cgctatctgt tttaggatca
    30601 ataattccgt atttagatgt ttcattttct ggtacacgca tgacggcaac agcggaagct
    30661 tgtgtttctt cataatccat catcaattgt tgagtcaatg ggatatcatc tttcatcaaa
    30721 tcatccccca gcatgacgac aaacggttca tttcctataa atgcttttgc ttgaagcacg
    30781 gcatccccca gtcctcttgg atgagattga cggatgaagt gaagattgac ttgagtcgtt
    30841 tcttcaacta aagcgagtaa ttctgttttt tccttttccc gcaaattgtt ttccaattcg
    30901 atatttgcat caaagtgatc ttcaatgggt cttttttctt ttcccgttac gatcaagatg
    30961 tcttcgattc ccgaatccaa tgcttcttcc acaataaact ggatcgttgg tttatccacg
    31021 attggaagca tttcttttgc catggctttt gttgccggca aaaaacgtgt tcctagccca
    31081 gcggcaggaa tgactgcttt tttgaccttc acttgct
//
LOCUS       DAYNVV010000028        30513 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.028, whole genome shotgun sequence.
ACCESSION   DAYNVV010000028 DAYNVV010000000
VERSION     DAYNVV010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.028"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..1028)
                     /locus_tag="ACGXWR_001474"
     CDS             complement(<1..1028)
                     /locus_tag="ACGXWR_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFK0803054.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1110..1799)
                     /locus_tag="ACGXWR_001475"
     CDS             complement(1110..1799)
                     /locus_tag="ACGXWR_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFK0803055.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1905..2273)
                     /gene="rplL"
                     /locus_tag="ACGXWR_001476"
     CDS             complement(1905..2273)
                     /gene="rplL"
                     /locus_tag="ACGXWR_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HFK0803056.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2326..2829)
                     /gene="rplJ"
                     /locus_tag="ACGXWR_001477"
     CDS             complement(2326..2829)
                     /gene="rplJ"
                     /locus_tag="ACGXWR_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HFK0803057.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3033..3160)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3239..3928)
                     /gene="rplA"
                     /locus_tag="ACGXWR_001478"
     CDS             complement(3239..3928)
                     /gene="rplA"
                     /locus_tag="ACGXWR_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HFK0803058.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4032..4454)
                     /gene="rplK"
                     /locus_tag="ACGXWR_001479"
     CDS             complement(4032..4454)
                     /gene="rplK"
                     /locus_tag="ACGXWR_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HFK0803059.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4797..5465
                     /gene="sdaAB"
                     /locus_tag="ACGXWR_001480"
     CDS             4797..5465
                     /gene="sdaAB"
                     /locus_tag="ACGXWR_001480"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HFK0803060.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5478..6350
                     /gene="sdaAA"
                     /locus_tag="ACGXWR_001481"
     CDS             5478..6350
                     /gene="sdaAA"
                     /locus_tag="ACGXWR_001481"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HFK0803061.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6441..7541)
                     /locus_tag="ACGXWR_001482"
                     /pseudo
     CDS             complement(6441..7541)
                     /locus_tag="ACGXWR_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324221.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            complement(7633..8520)
                     /locus_tag="ACGXWR_001483"
     CDS             complement(7633..8520)
                     /locus_tag="ACGXWR_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFK0803062.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(8597..9142)
                     /gene="nusG"
                     /locus_tag="ACGXWR_001484"
     CDS             complement(8597..9142)
                     /gene="nusG"
                     /locus_tag="ACGXWR_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HFK0803063.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9243..9413)
                     /gene="secE"
                     /locus_tag="ACGXWR_001485"
     CDS             complement(9243..9413)
                     /gene="secE"
                     /locus_tag="ACGXWR_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HFK0803064.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9437..9589)
                     /gene="rpmG"
                     /locus_tag="ACGXWR_001486"
     CDS             complement(9437..9589)
                     /gene="rpmG"
                     /locus_tag="ACGXWR_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFK0803065.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9751..10395
                     /gene="cbpA"
                     /locus_tag="ACGXWR_001487"
     CDS             9751..10395
                     /gene="cbpA"
                     /locus_tag="ACGXWR_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-AMP binding protein CbpA"
                     /protein_id="HFK0803066.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10451..10954)
                     /locus_tag="ACGXWR_001488"
     CDS             complement(10451..10954)
                     /locus_tag="ACGXWR_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFK0803067.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10967..11013)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11551..12516
                     /locus_tag="ACGXWR_001489"
     CDS             11551..12516
                     /locus_tag="ACGXWR_001489"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFK0803068.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12615..13787)
                     /locus_tag="ACGXWR_001490"
     CDS             complement(12615..13787)
                     /locus_tag="ACGXWR_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0803069.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13774..14919)
                     /locus_tag="ACGXWR_001491"
     CDS             complement(13774..14919)
                     /locus_tag="ACGXWR_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0803070.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14933..15865)
                     /locus_tag="ACGXWR_001492"
     CDS             complement(14933..15865)
                     /locus_tag="ACGXWR_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0803071.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15982..17061
                     /locus_tag="ACGXWR_001493"
     CDS             15982..17061
                     /locus_tag="ACGXWR_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFK0803072.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17058..17687
                     /locus_tag="ACGXWR_001494"
     CDS             17058..17687
                     /locus_tag="ACGXWR_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFK0803073.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17797..18024)
                     /locus_tag="ACGXWR_001495"
     CDS             complement(17797..18024)
                     /locus_tag="ACGXWR_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFK0803074.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18127..20715)
                     /locus_tag="ACGXWR_001496"
     CDS             complement(18127..20715)
                     /locus_tag="ACGXWR_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HFK0803075.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20735..21394)
                     /locus_tag="ACGXWR_001497"
     CDS             complement(20735..21394)
                     /locus_tag="ACGXWR_001497"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFK0803076.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21443..21946)
                     /gene="trmL"
                     /locus_tag="ACGXWR_001498"
     CDS             complement(21443..21946)
                     /gene="trmL"
                     /locus_tag="ACGXWR_001498"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HFK0803077.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22167..23033)
                     /locus_tag="ACGXWR_001499"
     CDS             complement(22167..23033)
                     /locus_tag="ACGXWR_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFK0803078.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23142..23783
                     /locus_tag="ACGXWR_001500"
     CDS             23142..23783
                     /locus_tag="ACGXWR_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HFK0803079.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23845..25206)
                     /gene="mgtE"
                     /locus_tag="ACGXWR_001501"
     CDS             complement(23845..25206)
                     /gene="mgtE"
                     /locus_tag="ACGXWR_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HFK0803080.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25224..26123)
                     /locus_tag="ACGXWR_001502"
     CDS             complement(25224..26123)
                     /locus_tag="ACGXWR_001502"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFK0803081.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26125..26922)
                     /locus_tag="ACGXWR_001503"
     CDS             complement(26125..26922)
                     /locus_tag="ACGXWR_001503"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HFK0803082.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26900..27604)
                     /locus_tag="ACGXWR_001504"
     CDS             complement(26900..27604)
                     /locus_tag="ACGXWR_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HFK0803083.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27735..28310
                     /locus_tag="ACGXWR_001505"
     CDS             27735..28310
                     /locus_tag="ACGXWR_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HFK0803084.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28428..29105
                     /locus_tag="ACGXWR_001506"
     CDS             28428..29105
                     /locus_tag="ACGXWR_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP adapter SpxH family protein"
                     /protein_id="HFK0803085.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(29195..30490)
                     /locus_tag="ACGXWR_001507"
     CDS             complement(29195..30490)
                     /locus_tag="ACGXWR_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFK0803086.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT         8986 a         6433 c         5513 g         9581 t
ORIGIN      
        1 acagtattat ttcggttgct tgctgcttca cctagccctt gtactcgtgt ttgattggcg
       61 acttgaccaa attgattccc gacgtctaat aaaataatag ctaaaagcaa aatggccaaa
      121 tggcttccgc caaccaataa agcaataaag cttattgttt gcataacaag tcccatatac
      181 acgatttttc tttcagaata agaatctgcc agtcgtccca cgataggtgc agcaactgct
      241 ccagacaaac caaaaatcgc taatatccct gcttcgaatg ttccccaatt gtaggcggga
      301 ctgctgatat aaaaaatcaa cgtagaccaa aagatcgaaa atgttccaaa catgaaaaat
      361 ccactgactg ccgcttctct taatagacgt tgagaagcaa ctaaatgcgg caaactttta
      421 agtgaatcaa ggtatgaaac agctgtacta ctttgctgga cagaacgcgg cattttccag
      481 taaagcagaa gtgtaagaat tccgactgca cataaagcaa ataaatagat catccgccaa
      541 gaaaaaagac tggcaacaat accagatacc gtccgagaaa gcaaaatccc cacgagtaaa
      601 ccgctaagca atgtacccat gaccttccct cttgcttttg gtcccgctag taccgcaccg
      661 taaggaatga tgatttgcgg cacgatcgaa agtaatccta ttaaaaaaga agcgcatgca
      721 aataacgtaa acgaaggcgc aaaaaaagcg gccaacagag agacggcaga taacgctacc
      781 attcgaatga tcaattttgg acgatccacc acgtccccta aaggaactaa aaacagtaac
      841 cctaacgcat agcctaattg ggtcaacatc gtcaatatcc cgactgcact tgtgctaaca
      901 gataaactag ctgctacttt tgttccaatc ggctggatgt aatacatatt ggcaacaaca
      961 acgccacaag tgattgataa tagtaaaata agcgaagttg ttaaaggtgt tttttcatta
     1021 ctcttcattg atttccccca tttcctatct tagtttacaa cttatggaaa agattggaaa
     1081 tagaaaaata caactattcg ccacacttat tatttgtgct tttgttttcc ttgttttttc
     1141 ttgcgatctt tataaatgaa gacaactaac cctactagca cagtaacact tgcaaccaac
     1201 gtgactgcag ttttgttata tccgtgaaac agagcttctc caccacacgc atacaacaca
     1261 gacgaaggga tgactccaat cacgatcgac aatatgattt gctgtagagg caatttcatc
     1321 gcatctgcag caaaattgac catagaagat ggaataaccg gtatcatata gcctaacatt
     1381 acacctattt ttggatgttt catttgtcgg attgcttgca cccaatgatt cgtttcggtt
     1441 ttcttatcta aaaattttaa gcgatgcata aggaaaattg cagtgatgtt accaagagca
     1501 ttacccaaaa tgttgatgat cgcacctgtc agtggtccaa agctcaaacc agcaatgact
     1561 ccaactactg aagtaggaat acctggaaca gcacacatca ccgctgtcaa tacgatcaag
     1621 agtatcgatg caaaagtccc atgcgaacga atatgtgcga gtagctctgc cttactcgct
     1681 ctcggattta aaaataattg gatgtctgtc tgatattcta aatacaaccg atagcccact
     1741 accagtatca gaatgattcc caacgagatc aacatcaatc ggattatttt ctttttcata
     1801 tttcctcctg aaaaaaatct atattcatta aataatagtt taacataaaa acaaaaaagc
     1861 accgaaatcc aacataggat ctcagtgctt ttaaatagta aaaattattt aacagttaca
     1921 gatgcgccaa cttcttcaag tttagctttc aattcttcag cttcttcttt agatacgcct
     1981 tctttaactg gtgcaggagc gccatcaact acagctttag cttctttcaa gcctaaacca
     2041 gttgcttcac gaactgcttt gataacttta actttttggt ctccagctgc agttaattct
     2101 acagtgaatt ctgtttgttc ttcagcagca gcagcgccac cagcagcagc tacagctaca
     2161 ggagcagcag cagatacgcc aaattcttct tcaatagctt taactaggtc gttaagttct
     2221 aggatagttg cttcttttaa ctcagcaacg atgttttcaa tgttcaatgc cattataatt
     2281 tcctccgttt aattgttctt ttttatttaa tgctttatgc ggcaattaag ctgcatctcc
     2341 atcttctttg tctgccactg ctttgacagc gtaagccacg ttgcggactg gcgcttgtag
     2401 tacagatagc aacatagata gaagtccttc gcgatttggc aattttgcca atgctgtgat
     2461 ttcttccaat gaagagactt taccttcgat gataccgcct ttgatttcta atgcttttgc
     2521 ttctttagca aattcgtcca tgattttcgc tggtgcgact acatcttcgt tactgaatgc
     2581 aacagctgta ggtccagtga atacttcgtc catgccttca aggccagctt ttttagctgc
     2641 acgtgaaaga atagaatttt tgataacttt catttctacg ttagcatcac gaagttgttt
     2701 acgtaaacgt gttacttcat caactgttaa tccgcggtag tcaacgacta ctactgatgc
     2761 agctgctgta aatttttcgc ttacttcatc aacgattgct gctttttttg cgataattgc
     2821 ttcactcatt tttgagtttc acctcctgaa ttttgatgga agagtttttt gcactgaaaa
     2881 ggcaagtcac ttttatagtt actttgctca accagtatta ttcatcacct attcacttcg
     2941 ttcatagtga ttctactcgc tttgctcgaa aggaaactcc tttcgctttg ctcaaccagt
     3001 attgttcatc atctcttcac ttcgttcata gtgattcaca ataaaaaact ctatgccacc
     3061 gcagacatag agggactatt gaatatattc aataaacgtc ctcggtagga aattaaggct
     3121 tgatgccacc tactgtcttc ggtacaagtt aattattaac ctcaactagc ttagcatgct
     3181 aaactagttg agtcaagaat tatttttcag ttggatcaat caacattcta atatttaatt
     3241 agaaagaagc ttggtcaaca tggataccag gtccaaatgt tgttgtgatc gttacatttt
     3301 tcatgtattg acctttagct gctgatggtt tagcttttag caatacatca tggattgctg
     3361 caaagttttc aactaatttt tcatcgtcaa atgaaacttt tccgattggt acatggatat
     3421 ttccagcttt gtccacacgg taagttactt taccagcttt cacttcgttt actgcttttg
     3481 ttacgtccat tgtaactgta ccagttttag ggtttggcat taagcctttt ggtcctaata
     3541 ctcgtcctag acgacctaca gtagccatca tatcaggtgt tgcaacaact acatcaaagt
     3601 caaaccatcc gttttggatt ttttgaacca tgtcgtcgtc acctacgaaa tctgcaccag
     3661 ctgcttcagc ttcttttgct ttgtctcctt tagcaaaaac taaaacagtt tgtgttttac
     3721 cagttccgtt tggtaataca acagcaccac ggatttgttg gtctgctttt ttagggtcta
     3781 cgttcaaacg gtatgcaact tcaactgttg catcaaattt tgcaatgttt gtttcttttg
     3841 ctaaagctac tgcttcggca acaggataaa ctttacttga atcaactttt tttaatgcat
     3901 cttgcatttt tttgctcttt ttagccattt tggttcctcc ttgattgtgg ttataacggt
     3961 tgtacctccc acgtgttcta tatctttcaa tatagagcca actgagaagc tgctgtctta
     4021 gggtgtatag attattctac agtgatcccc atgcttcgtg cagttccttc aaccatgcgc
     4081 attgctgctt caacgttagc tgcgtttagg tcttccattt ttaattcagc gatttctctt
     4141 acttgatcgc tagaaacttt cgcaacttta tttttgtttg gttcgcctga acctttttcg
     4201 attttagctg cttttttcaa tagaacagca gctggcggtg tttttgtaac gaatgtgaat
     4261 gaacggtctt cgtatacaga aataacaacc ggaatgatca aacctgcttg atcagctgta
     4321 cgagcgttga attcttttgt gaatcccatg atattgatac ccgcttgacc tagtgcagga
     4381 cctactggtg gagctggagt tgctttacct gcaggaattt gcaatttaac gattttttct
     4441 actttctttg ccacgagaca tacctcctta agtccgtgat gtggttaatt ggagatgcat
     4501 atttctcctc ccacgtttta tctgatctga aaaaatccag acaaataatg tgcaaaacaa
     4561 tgcacactgg tacagtatag caaatttatt tgttttttca agattttttt ctgctatttt
     4621 tacattttgc ttgaataaac gctaaattta ttctaaaaaa acaacaattt ttcgttctca
     4681 tttcttcttt tatgttacac ttgcgctagc atggttcaac agatgaaagc aaacaataac
     4741 acggtttttt agacccttgt acaaagattc ctacataaca aaatgaggtg gagaaaatga
     4801 aagatttaag gtatagaagt gtctttgata ttattggacc tgtgatgatt ggtccaagta
     4861 gctctcacac tgccggagct gctagaatcg ggaaaatcat acgtagtata tttggcgaac
     4921 agcctgattc tgtagatatt tatctatatg aatcatttgc aaaaacctat cgggggcacg
     4981 gaacagatat tgcattagtt ggcggcctgt tagggatgga acccgatgat gaacgtttag
     5041 ctgattcttt gaaattggca tatgaagccg gtatggaagt cttgtttgtt cctaagagtg
     5101 aaaaagccga acatccaaac tctgtaaaga tgcttctaaa aaaaggaaca cgaaagcttt
     5161 cagtcactgg catttcgatc ggcggtggca atatccagat ttctgaattg aatggattca
     5221 aaatttcttt aagcatgggt actcctacct tgatcgttgt ccaccaagat gttccaggta
     5281 tgattgctaa agtgactagt atactttctg agaccaatac gaatatcggc actatgacag
     5341 tgacacggga atcaaaaggt gaaaatgcca ttatgataat tgaagtagat gatcctcaag
     5401 tagaagaaac ggtaaaaaga ctcaaacagc tgccaaatat cgacagcgta aattatttcg
     5461 attaaggagc taaaaaaatg tttttatcga ttgaagaatt agtagatcaa gcaaaagctt
     5521 atccaagtgt agcagaattg atgattgcag ttgaaatgga aatgagtggc cgttcccgta
     5581 gtcacatcat cgagatcatg gaaaaaaacc tctcagtaat ggaacaatca atcaacgagg
     5641 gaaaagaagg tgttacctcc gtcacaggaa ttaccggtgg tgatgcaaaa aaattagatg
     5701 attatttaaa tgaggcagac tttttaagtg gagaaacaat cttaaaagct gtacgcaatg
     5761 ctgtagctgt taatgaagtc aatgcaaaaa tggggttgat ttgtgctaca ccgactgccg
     5821 gaagcgcggg tgttgttcct ggtgtgctga tggctgtccg agatcggctt gatttgacac
     5881 atgaacagca attggaattc ttatttaccg ctggcgcttt cgggttagtc atcgcaaaca
     5941 acgcttctat cagtggtgca gaagggggat gtcaagcaga agttggttct gcaagtgcaa
     6001 tggcagcagc agctttggtt tgtgcaaaaa atgggactcc tcatcaagca gcacaagcag
     6061 tagccattac attgaaaaat atgatgggac tgatttgcga tcccgttgca ggcttagttg
     6121 aagtcccgtg tgtcaaacgt aatgctttag gctcttctca agcttttatc tctgctgata
     6181 tggcattagc gggtatcgaa agtgtcattc cgccggatga agtcgttgct gcaatgtacc
     6241 aagtcggacg tcaaatgccg tcgattttca aagaaacagc agaaggtggc ttagctgtta
     6301 cgccaactgc taaacgactt gcggaagaga ttttaaataa gagggcgtga taaagctcct
     6361 taatttcgag tattaagaga ttagttatct tcataacaaa aaacgaagag aggactaatt
     6421 gcccttctct tcgtttttta ttaatccatc aatttcgtat tttttacttc atcgatcgtt
     6481 tttgttcctg caagttgcat cgtgatcgac aattctttgt tcaggtgttc aaaaacagat
     6541 gttactcctt ctgccccacc tagattcaac ccataaatca ctggtcggcc aatcgcaact
     6601 aagtcagcac cacttgccag agctttgaag acatgctctc ctcgacggac accagagtcg
     6661 aaaatcactg gtacacgttt gttgactact tcggcaattt ttggcaatac ttcaaaggac
     6721 gcaggacctc catctaattg acgtccacca tgattggata cccagatacc atctgcccct
     6781 gcagagatag cgattactgc atcttctggc gattgtattc cttttacgat aactggaaga
     6841 tgggtgattt ctttgattgt tttgatgtca tctggtgtca agccttgttt tgcagctgca
     6901 taaatttctg cgattccttt tccttcgcca ttaccacttg cactttgttc gctatacgca
     6961 gctaagttag gcattggtaa tggaaattgg aattgattga tgacgtcttc ttcacggtaa
     7021 ccaccgagcg ttgaatctgc cgttaaaatg atagctttag cccctgcttc tactgctttg
     7081 ttcaaaatga actcattgaa tctgtcgtct ttactcatat ataattggaa aaactgcggt
     7141 gcgcctggcg ctgcatcggc tgcgtctttg attgtcgtat ttgcataagt gctgatggaa
     7201 aagattgatc cagcagcagc tactccttta gctgtatcag cttccccttt ttcatgtgcc
     7261 aatccttggg ccgctgatgg cgcttggata atcggtgtat ctaattcaat tccgaaaaca
     7321 gatgtatgca aatcggctga gtcgattccg cgtaatatcc gtggcatgat tttctttgta
     7381 ttaaaagaag tcgtattttc tttcatcgtc cactcatctt cagaaccacc gcgaatatag
     7441 ccaaaagctc ctgcttccat gcgctctttt acacgacctt ctagttaggc aatgtttaca
     7501 atatcgattg gatgttcttc attacttgta tgataagtca tagtagatcc ttctttcatc
     7561 ttcttgatta catataaatc atactaaact tacaaaaagt aagcaaacat ttactctcag
     7621 atacttttat cgctattctt tccaaataaa tcgacttaca agctgatcta cttcttggtt
     7681 ttcatgaagc atactatgag aggcattttc acctgtcact actttttcct ctatttcatt
     7741 tccgcgttgc ttcaacaacg catagaccgc taatgcactg tttaacggta ctgttccatc
     7801 actcaagtct gtttcatcta gttgaccagc aatcaagaaa aatcgagtgg ttataggaat
     7861 attaccgatc atttgctggt aatcttgata gcggttagaa acgacagcag gcccctttgc
     7921 taactcatct gtcagagact gcgcactatc atcgacaaaa tcattaaaag gcgcgccaat
     7981 tgctgttaat gtctgaactt gtggcaatga cgtatcctgt ccatacgttc ctaaatagcg
     8041 tagtgcacta actcctccca tggaatgccc cactatgttg actttatcta tgccgtagtt
     8101 ttctttcaga tacaaaagac aagttttgat ccattctgct tgattccact cgttattttt
     8161 attatcttca aacaatactt ggaccatcgg attgtctgct tttccagaca aatctcctgt
     8221 tgcttgtatt tgtccatctg ttcctactgt taaaaccaat tcttttactg cttgctgatt
     8281 tttttccaaa cgccgcaaca tccctttaaa ggaattttct gtcccgctgt agccgtggaa
     8341 aaaaagtgtt ggaatagtgg ttttttctat cactttactg gattctgccg ttttttcttt
     8401 atcagaaact tcagtagtat ttatcttcgt cgtctggcaa ccacttaacg caaacaaact
     8461 gataaggact aaagctgctg cagttgcacg tttgcataaa tttttgattg gttctgtcat
     8521 acacctcttc ctttccatat agaaaaaaga aagacttgaa aggccaatca tatgatcgac
     8581 atttcaagtc tctttattaa tcgattttat ctacttgatc gaaatcaagt tctgtactgg
     8641 tttcacgtcc aaacatatcg atgttgactt tcaatttttc tttttctccg tcaacttctg
     8701 ttacttgtcc ttctaatcca gcaaatgcgc cttcgatgat tttcacgact tcgccaactt
     8761 ctacttctag atcattttgt cgcaggctca taccgataga acgcaagata tgattgactt
     8821 cttctggaag taatggtgct ggtttgcttc cggctccgtg tgaaccaacg aatcctgtca
     8881 caccaggtgt gttgcggaca acataccatg aagcgtctgt catgatcatt tcaacaagta
     8941 cgtatcctgg gaatgtttta tgaacgattt ctttttcttt cccatttttg acttcagttt
     9001 ctttttcttc aggaacaacg acacggaaaa taaagtcggc cattttcata ctttgcgcac
     9061 gagattcgat atttgctttt actttgtttt catatcctga atatgtatgc aagacatacc
     9121 agtttttttc aaaagattcc attgaaggct cctcatttca ttgtaaaata aaaaaacctc
     9181 agtacacccg aagtttttct ttcgcttcat tatagcacta aaagtacgtt gtggctagcg
     9241 agttatttta aaatccagcc aaataagctt tggatggctg tatccattac gtaaaacatc
     9301 aatccgaaaa taatagaagt ttcgatgact actaacgtat ctttacggag ttgttttctg
     9361 cttggccaag ttacttgttt gatttcatct tttacgcttt ttagaaattt catgagacaa
     9421 cctcccttgc tactgtttat ttcgtttctt tatgtaatgt atattgatta caatatttac
     9481 aaaacttatt gatttccaaa cgttcgccgc tttttccttc actgactgat tttgtgtagt
     9541 tgcgagaccc acaaacggaa caagcgagtg ctgctttttt ctttgccatt tacttctgcc
     9601 cccttgctga gaatcagact tatacttcat aacagtatca cgtaactttt tacttgtcaa
     9661 tttgtgaaat aaactatcta ttgttttgga taaaattatg atatgattaa tttgaaatta
     9721 agctaaaatg agacaattgg aggtatagcg atgctattaa aaacacttgt atataagaaa
     9781 aaagatctga caaccgttac agagactagt acattagaag aagcattaaa aattttagaa
     9841 acttccggat accgttgtgt gccgatctta gattcttcag gtaatatttt ccgtggaaac
     9901 atttacaaaa tgcatatcta tcgtcataaa gcaaatggcg gtgatatgac gcttcctgtc
     9961 actcatcttt tgaaaaacgc tacaaagttc atttacctgg atacttcttt cttcaaagta
    10021 ttctttacga tcaaagagct tccttatatt gctgtccttg acagtgaaaa tcatttttat
    10081 ggtattttga cacatagtac gttgcttaat atgctctctc aatcttggag cgtagaacaa
    10141 ggaagctatg tactgacaat tgcttccaca ggaaagcaag gagatttggc tgctattgca
    10201 aaaatcattt caaaacacag cagcattgcc agctgtatta ctcttgatat cgaaaaagac
    10261 gaatacattc gacgtacatt gatcacgcta ccggctaaca ctgaagcgaa agtatgtgaa
    10321 acgatcgtca accacttaga gaaaaagaat tataaagtgg tagaaattga aaatttgcaa
    10381 aaccaagaag cataatcaaa aagcgaaaaa agaaaacagc taatctgctt tcttttttcg
    10441 ctttttataa ttagacacgc ttttcaaaat caagcgcgcg atctaaataa tacatcaatg
    10501 gtgctgaaac agccatgacg ataaactcac ttaatgcaag cgtgccatag gttgtccaaa
    10561 atgcttggcc acctgttgga actaacatat aagcaatcag tcccatgctg atggtaaaga
    10621 agatcgtgtt caatactaaa cgcatcttta catttttcac tttgttttgc aataaagctg
    10681 tcaggcctaa agaaagcaat gtttggccgc caccaaaaac cacatccatg ataccaaaac
    10741 caaagaaggc attatagacg atgaccccgc ctaaaactcc ccaaagcaat ttacggttaa
    10801 agacaactaa atgattcaaa ctttctgaaa tacgaaactg gatcggccct gaggatacag
    10861 gcgcaactaa aatagttaac gctagataaa gagccatgat gatgccattt acaacgatta
    10921 cggataaccg ttgtctgctt ttcgtttttt gcattttctc tcctcttttc tcctagtttt
    10981 tttaacgcgg gatggttgat gaaccgcggt tatgtgaaac aaacaataat tataacagac
    11041 ttttcattta tttcaatccg tcttatctgc ttttaaaaaa gcaaaagctt aaacaatgta
    11101 aacgtttgct aaaaatcgtg ggatatggta taaagtaagt gtaaggggtc ataagaattc
    11161 ccagtaaagc agacgaagta ggatctgcaa gaacagaatt gttgtgaaac ttaaataaat
    11221 aaaaaaggat gtgggaattt gagcaacctc ttactagaga acggtctagc aagcagctga
    11281 agatctaagt ggacatgccg aaccttggaa cttctcctta cgtaagtaat ggatcatgcg
    11341 cttgctaggc ttttttgtgt ttttcggtct tcggaccttt ttcattttcc tagacttctg
    11401 ctataataac caagaattaa ttttgtaaca gatttttttg aaaaaacaag tttctttcat
    11461 tcaaaaaata gaaaaagctt gctaattatt ggttaaccag caaacaggag tattaaaata
    11521 tcttgtttta ttgaatagca ggaggaaatc atgaaattcc attatcatat attgatcaat
    11581 ccatcggcag gcagcggaaa tggctataaa gtagcagaaa gaattttacc ggtattaaaa
    11641 aataagcata ttgactatac acttcattat agtgaataca aaggacacga tgctgagatt
    11701 gctgaaactt tggcaaaaga aacattgatt ccttggatag aagaagaaca gaaaacaatc
    11761 gatactttcc cccttttgat catcgtagga ggtgacggca ccttacatca ggtacttgat
    11821 actttctatc agatggaagt agaattccca gttgcttata ttccagcagg ttctggaaat
    11881 gattttgctc gaggggcagg ccttccaaaa aatcccaaaa aaggacttca gctgatttta
    11941 gcagctcaat caccagaaaa agtccacata atggcttatg aagaaaaaat aagtgaaaaa
    12001 aaaggaatag ctgttaataa tttcggtata ggattagatg cagctatcgt ccatgcgaca
    12061 aatcattctt ccacaaaaaa gcgattgaac aaatacaact taggatcatt ttcgtattta
    12121 ttctctattc tccgtgcttt attcactcaa aaaggatttc caattctggt agatgcagga
    12181 ggaaaacaat taagtttttc aaacgcattt ttatgtacag caacgaagca tccttttttt
    12241 ggcggaggaa tcgcgattgt tccaactgct gatgcgtcta aaccagtcat tgattttgtc
    12301 gtggtcgaac gaatcaattt ctttaaaatc ttgtggctca ttcttttact tatacagaaa
    12361 aaacaattga aatcgaaata tttccatcac tacacaacaa acagattacg tatcgtttca
    12421 acaacaccgc aacatggtca agaagatgga gaagaaatgg aaaaacgacc ttttgatatc
    12481 acaataacca caactaaaca gttgttttgg tgttaataaa agaggttttg tcagaagcta
    12541 catctggaac accgtttatt cggaaaaaag gactgtgaca cgacttttgt cacagtcctt
    12601 tttttactat gcagttaatt ctttgcccaa ttgggttgcc atcgatagtt tctttcttta
    12661 cccaaaataa attggatcat tgaaaacacc gcagcaaaag caactaagac acaaccattg
    12721 aaccaaaaag attctgcaaa tgtttgattg taactgagtg tttcactgat caagttatta
    12781 ttttgaacaa accaatatgt tggtgtgaat gccgctattt tgctaaccat ttctggcaag
    12841 tattctgctg gtacaaacac cccaccgata aagcaactgc ctgtgataaa aatatctttg
    12901 atcccaccgc tggtttctga gttttttacc aatgaagtga tacaagccga aaagctaatg
    12961 atcggcaata aaaacaagaa agtatttaaa atatgatacc ataccgttat atcccacgag
    13021 gtgtggatca ctaacagaac cattagaagt aagaagccac tgaacaacag cagcgagtaa
    13081 ctaatcaaac taaaggttac tttgcgattc aagtttcgtt tggtaatggg cgcactctgg
    13141 tttcgtttac tgatctcttt gcgattaaac gctagattga tgacgctgaa accgctaaaa
    13201 atggatagaa acaacccata agacaagaaa ttaaaggttg tgcccgtcaa cagctttttc
    13261 atccgctgac tatatcccgc acttagctca acttctccag taaccgagag tgccatttgt
    13321 gtctgttcca tagctgcatc gattgtttta tcttcttctt gaaacagaat cagtgtttgc
    13381 aaaaaggtgt tcacttgctg tgtaacaact gttttagaaa aggcatctgg gcgactctgt
    13441 atcttgatcg tcgccatctt tcctacttcg acttgttcgg taaagtctgc aggcagatgt
    13501 aagataatgt ttacacgatt aaaataaaga gcatcatcga tttctttttg tgaggttcca
    13561 tccaatgtaa cgactgtttc cttgtcattc aaatatttac gaaggccatc gactacaggc
    13621 gactcttctt cactaatcaa ggcgattttc gcatcttgca gagaggtatt ttcaacatca
    13681 atattttgcg caaaaaagaa tgtggcaaca acagtgataa ttacacctat cagtaaattc
    13741 gatttatttg ctttaagcaa tgtccaaatc gttttataaa gcgtcataac gcacccctct
    13801 ttccatccaa gcatttccta acgcaaaaag gaaaataaat ccgatcaacc atagaagatt
    13861 ggtataaaaa ctagccaaat cagtgtagaa ataaagttta tacaaacttt cgctgatcaa
    13921 gttgacgaga tttaattgac caacaatcgg aatatgaaga tcaatccaat acttcacttg
    13981 ttccgacccc atcataccag caaaaaagct catcgcaatc gtcactgaaa tcaagatgct
    14041 atccttttgc accagattca tttttggtat caaattacca accaatgtac ctaacaaaat
    14101 cgcacacaac gaccccagag cggtaacaat catcaaccat tgccaacgtt caccaaagtc
    14161 tacttgatag ataaaacgaa agacagctaa cataatataa atctctgtca aaacaatcgt
    14221 aaagcttgct gccaaattag cgattgaaac taacgattgc tttctaggaa tcaaggacaa
    14281 gcgaatacca tttgacgatt gatttgcttg ctgatcctgt acattgcgga ccccccacat
    14341 cgtcccgtag agaatcgcca ttccaatcag agtgaagaaa taaaaacttt tgaaactcat
    14401 attacgacct gcatgaactt cttgaaaaga tacttcttgt tcaaaaacag tcatgatggg
    14461 cgcgagatca acgttctcca cttctgccac tttactcgaa attataccaa tacgctgtaa
    14521 aaattgatcc atgacgtttt tcatcaacgt ctgactcatt cctgcttgac ccacatggag
    14581 cgaaacagat gaaccatcaa tgagataaaa accagccaaa tcatctgcat ttagcttttc
    14641 attcgcttct acttccgata gttcctgtac ttcaaataat ggtttatcat tgacttcgac
    14701 ttgttctaag actgtggtaa aattttccga aagcgctgtt tgatccgctt tgattacaat
    14761 tccagtatta atcgtttcaa gattgccacc ttgatcaatc tcgccaaagg ccgccataaa
    14821 catcaatcct aaaagaattg gaaaggccaa tgtccaaaac aacatggatt tatttcgcag
    14881 cagtattttt gtgcgatatt tataaaaatg ccaaaacatt atttcccctc ctctagtctc
    14941 tcaaatcctt gccagtaatc tctaaaaaga catcattcaa ggacgcttct ttggttgcta
    15001 tttttccgta actgatcttt tcttcttgta agattgtaag aatcggcaac aatactgtat
    15061 ttagttcagt agttgttact tggagctgac cttttttata agcgattcca tcagaagcta
    15121 ttgttcgctg aatcgctgac aacacatttt ctgggagtaa tgggatgtcg atcgtcaaac
    15181 gatccgccgt ccgtaccata tcttttagag attctttggt tcctttagca atcacctgtc
    15241 cttgatccat gatcacgatc tggtcgcaaa gaatttctac ttcttccatg taatgtgttg
    15301 tatagacaat ggttgctcct tgtcgattca gctccttgat actttctaaa attttattcc
    15361 gactttgggg gtctacagct actgtcggct catctaaaaa aattaaccgc ggcttgtggg
    15421 caatcccaca tgcgatgttc aaccgacgtt tcaagccacc actaagttct cctggacgaa
    15481 acgaaacata tttttctaat cccactaatt gaatcacctc ttcaatcaag gctttccttt
    15541 tctctttttc ggaaacatat aaaccgcaaa aataatcgat attttcttgc acacttagtt
    15601 cgtcaaagac cgcaacgtct tgaggaacga ccccaatcat tgccttgaca gcataatttt
    15661 caggagtcat tgttgtcccg aacaatttaa tggttccttt gtcataattt aacaaagaaa
    15721 gcatacagtt gatggcagtc gatttcccac tgccgtttgg acctaacaga cctaagactt
    15781 ctccttcttg tacttgcaga tcaaaatgat tcaatgctac aaaatctcca tagcgtttga
    15841 ctaatttatc aatttcgata atcatcatga aaaactcctt ccaaatttct tgttgatctg
    15901 actataataa agtgcaagaa aagaaactag tgacgattgg ctaaaccaca catgacattt
    15961 gtcacaatga aggagtctgc tatgcataaa tctcggctac tcaacgaaac tagctttcta
    16021 ctggttatct cattgctttt gctggtaagt caaggattcg ttgctatgca agttatctat
    16081 ttattgatcg ccgttttatt cactggtgtc agttatttac tgcctacaaa gccaaattgg
    16141 attttccaag ttattctatt tcttttatgt gcctttttac ctgatcttgt cctgtttctg
    16201 ccagcgacga tgcgagtgat cgcccctgaa gaaagccacc ttgattactt gtttttgtta
    16261 ggttttttgt tgatttcgac ggttggtaat catcccccca tcaaggtcgc ctttgtcgta
    16321 attttgctgt ttttttcctt ttacttacga aaaaaagatc aacgaacgac cgatcttgag
    16381 aaaaagtaca ttgtctccaa agatactcat tgggaaaaac aacaagagtt atcggaacaa
    16441 aataaagcat tggccctgtc acaagaaaca caattagcct tgcaaattgt ggaagaacgg
    16501 aaccgaattg cccgagacat ccatgacaat gtcggtcatc tgctgtcaag tgcgatttta
    16561 caaattggtg cgcttgaaat gatcaatcaa gaaccaaaac taaaagaacc attagaaaat
    16621 ttaagtgcca ccgttcacac tgggatggat cggattcgtc aaagtgtcca tgacctccat
    16681 gagacatcga tctcttttca acactcctta gagtttctga tcgctgattt tccttcttct
    16741 gttacgattg aaggaaactt gtttgaagga ttgaatgaaa cgcagcaaaa ctgcttctta
    16801 atggtcatca aagaagcctt aaccaacagt atcaaacata gtcatgccaa aaccgttgtt
    16861 ttacattttc gaacgttgcc ggccttttat cgcttgcaaa tcacgaatga tggcaccagc
    16921 ccacaaaaaa attctgctcc cggtattggt ttgaaaacga tgcgtcaacg tgttcaagaa
    16981 caaaagggac aagtccatat tttccaagaa aaccagcaat ttcagttaac gatcatttta
    17041 ccaagggagg gacaccaatg ataacagtag tcattattga tgatgatcca tttgtgacga
    17101 aatcgttaca aaccatttta gaaagcacga aagagatccg tgtgttaggc attggtcatt
    17161 gtgccaagga tgcgctagtc ttatacgaaa cccatcgtcc cgatgttttg ctgacggaca
    17221 tccgcatgcc taaacaaacg ggcatcgatg ctgccaaaga aattttggct aaatttccca
    17281 aagccatcct tttgcttttg acgacattca aagatgaaga atacatccgc gaagcatttt
    17341 ccatcggtgt caaagggtat ttaatcaaac agaacttgca agcgattatt ccttctgtca
    17401 aatccgctta taatggacag gccgtatttg gtaatgaaat catcgagact ttcactcaaa
    17461 tgatgaagaa taaaccgacg attgatagtc atgcttatgc ttcttttagt gaacgtgagc
    17521 ttgcaatcat caaagaagta gctgccggga aaaacaataa agaaattgca gatgccttgt
    17581 acttgagtga cggcactgtt cgcaattaca tcagccaatt actagaaaag ctagatttac
    17641 gggatcgcac gcaattggct atctattttt atcagcattt gcaataagtc ttatctaaca
    17701 caaaaaaacc tgaatgatgc tccttcgcat cattcaggtt tttttcacat cttctattca
    17761 attgtcccgc aaaccatttc ctcacgattg aaagaatcaa ggattcgcag ggctgccagg
    17821 attcgttgga ttgttcggcg tgttaggcgg aaaaataggc gccttgtcta acgttttttc
    17881 tagttttgat tcttcacgat cgtctcgttc tacatcagga ctttcattca atttgaattc
    17941 tttttccatc tcatctaact ttttaaagtc attgccagat tcttttgcta atttcgctaa
    18001 tttatcttcg gtttctttag ccataaagta acgcccccct tttgatttca gcttagcata
    18061 tcacactgaa aaaacaaaag aaaacgctaa ccaacgatca tttttagcta tttctcatct
    18121 ttaaaatcaa gcattttttg ccggtataaa atcgtaggga gaactgtttt ccataccaat
    18181 catcggatct actaactggt tatcgatcac ttctgctgta agaacgaaat ctttagaaac
    18241 agcaggttct acctcttctt tcttttcttc tccaacaaat gaagaaaaca gatctggttc
    18301 cactgtttcc attacttggt ttttcgtttc attcgtccca ctgtcatctt ctacaggtag
    18361 cttttctttt acaacccgtg gctcttttgt atagttccca tcttcaaatg gatcatttcc
    18421 gaccaaagaa tcttcataag ctgctagttt ggtccggaga gtgatattca ttttatcatt
    18481 atccatgatc cttgatttca acgtagtcat ccggcttgct gattcattcg ctacacaagt
    18541 gacataggct tgctcttccc ctaacaaaat caacagttcc ttactgcgag tcactgccgt
    18601 gtagagcaaa ttacgctgaa gcatccgctg atattgatgg accatgggca aaataaccat
    18661 cttgaattca ctgccttgtg atttatggat tgagcaacaa taagaaagag tgattttatt
    18721 ccattcgttt cttttataag tgacctcatt tgcatcaaac tggataacta attcatccac
    18781 tttatcttca gaatcttttg ccaagatgat acccgtgatt tctcccatat ctccattgaa
    18841 tacattcaat tcgggagtat tgactaattg gaggactttg tctcctatcc gataaacggt
    18901 gtcgttccaa tgtacttcct tttttccagg tttccctgga ttgaatatct cctgcatcat
    18961 tttatttaac gcatcgatcc ctgcaggtcc ccgatacatt ggtgctaata cttggatatc
    19021 ttgtgcacgg aatcccttat ttttcgcttt ttccacaatt ttagagatca agggttcaat
    19081 ttgataagca tcacttcgga aataggaacg atctttttga ttctttgtga aatcttttgg
    19141 cagacgtcct tctttgatct catgggcaag aggaataata ctagaaccat caccttgccg
    19201 ataaatctga ttgagttcca ttttgggaat ttgttcgatt tccaaaagat catggagtac
    19261 ttgaccagga ccgacagagg gaagctgatc tttgtctcct actaagataa cttgcatatt
    19321 cgtcggaatc gctttgaata atgtgttagc cagccatgta tcgaccatag acatctcatc
    19381 aacaatcaaa agtccgcctt ctaattcttt cgtactgact gaaggtgttt tttcccgtcc
    19441 attcagcccc agaagacgat ggatcgtact ggcaggcaga cctgtcgttt cgttcattcg
    19501 tttagctgct cggccagttg gtgctgcaag tagaatagga aaaatttctt gggtatattt
    19561 tgaaggatcc aattccagtc cgttcaactc tgcaaaaaga ttgacgattc cgttgatcac
    19621 agtagttttc cccgtacctg gtcctcctgt taaaataaat agaggggaac ggattgcttc
    19681 agcgatagct tgttcttgcg aaggtccata ctgtatgccg aatatttttt cgatacgccg
    19741 aatattcttc tgcacttctt tttcaggata atggatttct tttttacgac tgagaaggcg
    19801 ctggatcgaa ttaccgatcc cccattcaga aaagtacaaa ctgttttcgt aaagattagt
    19861 ctcttcttgt tgtatctttc cttcttcaac aagttggata attacagtag caacctgatc
    19921 aggctggatt tcaattgggc gacttgtttc taaaatacgg atcgtttgct gaagcaatgt
    19981 ctccgccggt acgtatgtat ctcctgtttg aactgcatgc tgaaaaatct gatgcaagat
    20041 agctgctcga attcttctcg gtgaatctgc tgcaataccg atttgttcgg ctagattatc
    20101 tgcacgtttg aacccgattc cttctatgtc ttcgactagc tggtacggat tttcttcgat
    20161 gatatccaaa gactcgttct tataggcctg gtagatactg aaagctaact gactaccgaa
    20221 cccgtaacga ttcagtccca tgatcacttg atccatcccg tggtttagcc gaatcgtctc
    20281 agcaagcatt tctctttttg gcttcgtcaa accggagatt tgttttaata ccgaaggatc
    20341 agcaatgatt ttttcgatag catcttctcc cagcaattct acaatttttt ctgctgtttt
    20401 cttcccgatt cctgggaatt tttcgctgga aagatacgct acgatcccat ttgcagttgt
    20461 tggcttttct tgctcatatc tttcgagttt aagctgcctt ccgtatttag gatgatccac
    20521 taattctcca taaaaacgat aagtctcatt ttcttgaata tcgccgaaac ttccggtgac
    20581 tacaatctct ttttcacggt aatcagctgt ggtttcactg atgtgtacca aaagcacttt
    20641 gtaaaaatta ctaggatttt gaaaaaaaat cgcggcaact gtaccaacga aataaggcat
    20701 ttcttctggc tgcatcggaa gccgcctcct tcttctatag taaaggttct ggtgctgttt
    20761 cagttcctaa aaaatctgtt tggttccata ctttcagttc atatggcaat aatctgcaag
    20821 gctcttcagt ctctaaaatc gtcaaactac tattgaacaa tccacccatt tcacgcaact
    20881 cacttagctc ttttcctgtc atccattgaa tggctgcagt taaagaagct ccatgtccta
    20941 cgaataaaag tgggccatct ttatgtcggg caaccgcatc tgctacaaca gtttcgatac
    21001 gtgtgattgc cgattcaatc gtttctccgt gaaaaggaga aggatcatac agatctaaat
    21061 gattacgcaa attcggcaga ttatccggat atttctggta catttcatcg atcgactgac
    21121 cttctaaagt acccagccct agttctctta gcttatctgt ataaaaaatc tctaccggac
    21181 gagcaagctc tttgttgata ccttctgctg tatcacgtgc tcgctttgct gtactggaat
    21241 aaattgcttt aaaaggaaca tattttacct ttttcccaaa tgctttgatt tcttcgtaac
    21301 tttgtggcaa aagcggagaa tcgccattgc tcccttgaaa acgtctttcc tgattccatt
    21361 gtgtcttccc atgtcgggta aaatatagtt ccatacgcag caaactcctg tctttctttt
    21421 attttactct ataataaact gtctaatcca gcttgtcatt ttcatagtga tgcgtcaatt
    21481 ctaaattagg gaatccttgc tggcgaagtg cttcatacac tatcattgca gctgtattcg
    21541 ataaattcaa tgagcggaca tgctcatcat tcatagggat gcgtaaacac ttttcttcgt
    21601 tttcacgcat aaatgtttct ggcaaaccgg ttgtttcttt tccaaataaa aagaagtgct
    21661 cttctccatc agcaaaattt tcgtcactat atactttatg ggcaaatttt gagatcaaat
    21721 gtagtttacg attacctaaa aatgttaaaa aagcttctaa attactgtgg taagtaatat
    21781 ttacatcatt ccaataatcc aaccctgccc gttttagatg tttgtcatca gttgaaaaac
    21841 ctagtggctc gattaaatga agcggagtat tcgtggctgc acacgtacgg gcaatatttc
    21901 cagtgtttgc agggattaat ggttcaaata aaacgatatg attcatcagg atcattcctc
    21961 tcatatttat gttcgtttct attttctgac aatttgattt ttgcataaaa aaaaacgtat
    22021 caactcggtg tcagtcactg cgagtcgtta cgttagtgaa gctcttctca ctaactttta
    22081 tcagaacagg aacctgataa aaaccaatga aaaaacaact tgttgctaat ataacaccct
    22141 caactttttt ttgcaacctc tactcattaa aaactgctag aaaaacgttt tctcttagtt
    22201 ccttttaata attctatgtc aattgtaatc ttcttcaaag gattcttata taagtctgct
    22261 ttgattcgct cttctacctg ccattctaaa ggtgacatgg ccaaaagatc tttttgattt
    22321 tcctctggta tctcaaattc ataggttaca cgctgacgtt cagttaattt cattgcttca
    22381 gcaaacttgg ctactacacg ttcattggaa taactctgtt tttcaggttg attcggataa
    22441 aaagcctgac gtagttcctt taaataattt tcttgtggca ccaccttcaa cacttctcca
    22501 tcttctgaga gtacacgttg gaattcttgg taatgagaag gcgaaaagat atttaaaacc
    22561 gcgttgaatg tttgatcagc aaacggcaaa ttggtcaaat cagctacaca ccaaaatgct
    22621 tcggcagatt gttctgtagc tgcgtagact ccttcttttg aaatatcaaa tccaacagca
    22681 ttttgaatct ttttcaattt tgaaagttca ttcaagaagc taccttctcc gcagccaaca
    22741 tctaatagcg agacttcttc aggtaaatgc tgcgcaatag tctcaataac gggctgatac
    22801 atgccagatt ggatcattct acgccttgga acgaacattc cttgatcgta ttctgtttta
    22861 accgcatggg ataaaaaata aagtgttcct tttttggaaa ggtcaaaacg gtgattattt
    22921 ttgcatatca agccattatc agactttttt acttcttctt ggcaaaccgg acagcggaac
    22981 agctgatgat tttctgccaa aaactggcgt cctcggtcaa ttttttttaa catagttccc
    23041 cctcatttct gttttatctt accgttagat gctcactttg gcaactgcta aaaatatgat
    23101 acaatgccta gaagaaagtg aaagataaag gagaagatta gatgatcaaa gaattttgcg
    23161 ctgaaaacta cacatctatt cctctagcaa ttgctagagg agccgatcgg atcgaattgt
    23221 gtgacaactt agcggtcggt ggcacaaccc cgagtactgg tgtgatcgaa gaaacgttaa
    23281 gttatgctgg ggaaaaagat atccccgtaa tgacgattat tcgtcctaga gggggcgact
    23341 tcgtctataa cgatatcgaa ttgaaaatca tgcatactga tttgattgaa gcaaagaaat
    23401 tagggacgga tggcgtagta tttggttgtc ttactccttc aggctggcta gacgaagagg
    23461 ccttagaact attgatcgaa acagcagaag ggttgcagat caccttccat atggcttttg
    23521 acagtattcc tgaagatcgg caattcgaag caatcgattg gctggtagaa catggtgttg
    23581 accgtatctt gactcatggc ggtcctgctg acaaaactat tgtagaaaat ttcccacggc
    23641 ttaaagaatt gattgcctat acagatggcc gcttaatcat tttgcctggt ggtggtgtca
    23701 ctgcagagaa tgcagcacat gtagctaaag aattgaacgt aagcgaagta cacggaacca
    23761 aaatcgtgga tcttcagtta taatcttata aacaaaaaaa catttgcaac aggcataatg
    23821 cttattgcaa atgtttttgt ttttttacat aaaatagccc ataaataaag aagcaatatt
    23881 gaaataaatc agtacactcg tcaaatcgct caaagtcgtg ataaagggac cgcttgctac
    23941 tgctggatca aatcctagac gatccattag catcgggatt aaactacctg caagattcgc
    24001 cactgtgatt gcaaatagca tagccatccc tatgacaaac cccaagataa aattatgttt
    24061 ccaaaaacct acgattagaa aaatcgtgat ccccgtaaca gctcctgtga caacgccggt
    24121 caagacttca gccaaaacaa gtcgaacaaa tccatgatct ttctcatcag aaatcgcaag
    24181 tcgacgaaca gccacagcta gcgactgggt tccagcatta ccggcagttc ctgtaatcag
    24241 cgaaatgaag actgctaaaa tactcgcttc acttaccaag tcttcatagt gactgattaa
    24301 agaagcggtc gacataccta aaaacaacag agtgatcagc caaggcaaac gtcgagacgc
    24361 tgcctttact ggattttcat taatttcttc cacattgacc ccggcaagtc ctgaataatc
    24421 gctagcagct tcatcatcaa taacgtcgat gatatcatcg actgtgacga ttcctaacaa
    24481 atgatcatca taatcggtaa caggaagagc taagaagtca taatctctaa atgtttgtgc
    24541 cacatcttct tggtcgtcgc ctacatgaac tgaaagcact cgttcgctca tcagatcaga
    24601 aatcattgcg tcgtcatcat tcacgattag gtcgcgcaga gaaataaccc ctactagctg
    24661 accttcttga ttaacgacat agatgtaata gattgtttca gctacatctg cttcgttctt
    24721 cagcacgtac atcgcagagc gaacagtttg attggctacg atcgaaacaa attcagttgt
    24781 catgatcgcg ccagccgttt catcctcgta atggagaagt tccttgattt cactggcatc
    24841 gtctgccgac atcaaactta aatatttagc aatttgcttt ttatccagcg tattaagcaa
    24901 gtcaacagca ttatctgtat acatctcaga aagcatatca gctgcatagc taggacgcat
    24961 ttcatctagg tattctttca tatgttcgtt gtcttcttca atcacatcga acatatccgc
    25021 taattcttta ggcgacagat aggaatagat cagctgcctg ttctcttctg taagagattg
    25081 gtagaattgc ccctgctcat agatatgcat ctctaaaaaa ctgtttctga atgcctgaat
    25141 attattttcc cttaaatctt gagtcaactg ggcaaatctt tcctctaatt cttgattttc
    25201 atccaaacca atctcacctc gccttattct tcaaaccgtc tcacaactgc ctccatgtct
    25261 gcggctaaag gctgcttgaa ctccagcaac tcttctgtaa atggatggta aaaacgcaga
    25321 tcataacaat gaagggcttg tctttttatt cccagatcca ttcgcccgcc atacatatca
    25381 tcaccgagca gggcacagcc aattgcggaa aaatgaactc ttatttgatg tgtccttcct
    25441 gtatgcagct ggatatcaac taacgcgatt tctgttagtc gcttctctat ccagtactca
    25501 gtctgtgccg aacgtccttc atcagagacc attcgcttca atagcgaaga ataatctcgg
    25561 gcgatcggca aatcgatatg tccatgtgcc gataaatctg aaagccttcc actgactaag
    25621 gcctgatatt ttttcacaaa cttcttttca cgaagttgca tatctaattt tgcgtgcgca
    25681 aatccatgct ttgcaaaaag catcaagcca gatgtatccc gatctagtcg cgtcaccaca
    25741 tggattactt ggttttcgta accttgtttt ttataataag cctttacacg attagccatt
    25801 gtcccatttg gatggtattg ggcaggaata gacgaaacgc ctgctggttt atttactacc
    25861 agaacgtgtt catcttcata cacgatatcg atcggtgttt catccaaaag tacggtttca
    25921 tgttctcctt cagcaggaat cacaatggtt accttatcat ccttagctag agaaaacaag
    25981 acattttcta cttgatcatt aactttgatt tgaccgcctt gaaattttat tttcgctaac
    26041 agaccctttg agatcccttt ttcttttaaa aaatatttta cttgctgaga atgatctttc
    26101 tcataatccc atgtaaactg catatcaatc ctcactaata aaggcatctt tcacacgatg
    26161 ccaaaaatgc atatgtcgat aagaagcaaa atggatccgt tcttctgcta ttcgataata
    26221 aattgagcgg atatttgctt ttgcgacatt caattgatca accgttacaa gataatcttc
    26281 tgtattttcc aattttattt ctagccattc atcatgggca atcacgatcg gagaacccaa
    26341 agtacgaaac actcgattat tcagtgaagc aatctctgcc aactgaaagg cattgatact
    26401 aggatggatc acagcaccgc cgacactttt attatatgct gtcgaaccag taggcgtaga
    26461 aatcgtcaat ccatctcctc taaaactttc aaacagctcg tttttgatgt atacatcggc
    26521 taccatcgta cgattggccc gtttaatcgt tgattcattc agtgctaaaa aatgctggtc
    26581 cggtgtttca tccaaataac tgatccgaac atccagcaag ggataactaa cactttgttc
    26641 ccggttcgtt cgtaagctgt ctactagttc ttccagctcg taatcccgcc aatccgtgta
    26701 aaaccctaaa tgacctgtat gcacgcccaa gaaacgcaca tcattcagac aatgactgta
    26761 gtgatggaac gccgacaata atgtgccgtc tccgccgact gagatgacca attctggctc
    26821 atgatcatct cgttgaatcc ctgcttgttc taaaagtgcg ttcaaacgtt ctgtcacttc
    26881 tatagtcttt gcttctttat tatgaacgat cgctactttc atcccctgcc tcctctcttt
    26941 cgctttcttt cttcaaaagc gttcgatagt agacatcatc tgattttcct cttccatggg
    27001 agaataaccg ctgtgcttct tggatttctt cacggatact ggacatctct tcatccaact
    27061 gataggcagc ttctgccgca cgctgaagtc gttcactcat ttcttctgga aaaacgcctt
    27121 gatatttata attcagcgaa tgctcaatcg ttgcccagaa attcatcgca agagtccgaa
    27181 tctggatttc cgccaaaatt ttcttctcac cgctgatcag ctgtacagga tactcgatca
    27241 ccagatgata agaacggtag ccacttgctt ttttatttgt gatgtaatct cgttcttgga
    27301 gaactttcat gtcttttctt ttacggatga tctcaacaac ttgatggata tcttctacaa
    27361 actgacacat gatccttaac ccggcaatat cagacatttc ttcttctaaa cgtcccattg
    27421 gaatatgccg taattgtgat tttgttacaa tactatcgac tggcttgact ctcccagtga
    27481 caaattcaat cgggacatgt cgattttgtt cacggaactg tttgcggatc ccccgcagtt
    27541 tcactttcaa ttctgataca gtttgttcat atggtgctaa aaatgcttcc caatctcgtt
    27601 ccatagctga tacctctact tcattaacat tcattgttta ttctaccata tatgcaaagt
    27661 tttttcgtac tcttgattta tgcattgacc aaaaaaagaa aattaggcaa aatagacaaa
    27721 aaggagtcga tcaaatgaca caaatgcttg aaatcgaata taaatctatg ctgacaaagc
    27781 aagagtacga gatattcatc gctcactatc aattaacaga taaagatttc cgtgtacaga
    27841 ctaatattta tttcgatacc gttgatgaac agctgaagaa acaaaattgt ggcctacgga
    27901 tccgtttcgt tggtcatcaa gctgaatata cattaaaaac acctgctgaa aaagggcgtc
    27961 tcgaaacaac ggataccttt ataacagaag aagcagaagc atttatcttc gaaaaacgtc
    28021 tgcctcgttc aggcgcagtt tttcaaaaac tttctgattt gaatatcgat cctgcttcat
    28081 taatccaaac cggaaagctt acaacaaaac gagctgaatt ccctattgaa gaaggacttt
    28141 tagctattga tgaaagctgg ggagacaatc tacacgattt tgaactggaa ctagaggtag
    28201 gggatgcatc tgtgggaaaa attgctttta taaatttttt aaaacgtttt tctttacctt
    28261 atcgtcctgc taagaacaag atccaacgta tgcttgaagc taaaaattag aaacctttca
    28321 ttttcacaag gcacttgagt tcattttttt acttttttct gttaagttat aggatgtgaa
    28381 agaatctagt cactagttgt atagaatcta ttttggggga gattcatatg atcgaaatct
    28441 atttatttgt taatccttta ggggaatact gtttcgaaat ggaacaacag ttattacaat
    28501 ttatcgaaga agagtacggg acaccatcaa aagaaaagat gcaatttcgc tttcttcctt
    28561 tggtcaattt gcagacaatt ggggatgtca tgcaacaaaa aggaatttct cagaacaatc
    28621 ttgaggaacg taatcactta ttctcaatga cttattctgc agcattggac tgcaaagcgg
    28681 cgcagtttca aggaaagaaa aaaggccgcc gttttttgat caaattgcaa gaagcagtcg
    28741 gctgtaatga cataccatat tctcaagaac ttgctgaatc catatttgaa gaaatcggcg
    28801 gcgatttgaa tatgtttaaa gaagatcgtc agtctgactt cgttaaagaa gtattctttt
    28861 ctgatcaaaa aattgctcgg gaaatgggca tcacaaaaca cccttctgca gtcgtttaca
    28921 attatgcctg cgaccgtgat tttggtgttt tagtagaagt aaaaggtaca agtagccttt
    28981 ggagaatcac agagctgtgt aaaacaacag ataactcata tcaagttttt aatggtgaac
    29041 atttacatac aaatgattct cagttccatt caagaactag ccatttacac ttgctttcta
    29101 attaaaaaag gctctttgtc aaatgatgtt ggtaaagaga aatcttagaa taatttggac
    29161 agaacagaaa gaagaaaacc tctttctgtt ctgtttattt ggttaaaaat gttttgccat
    29221 gacgaatcat aattcgtagt ttgaaattgt aaaagttgcg aaagccgtac gcattgcgtt
    29281 ttaatacttt gatgtggttg tttaagcatt ccaatggtcc gtttgaatag ctgtagtgaa
    29341 gcgcattttg gatctgtggc agaaactttt taaacgttcg taaagtggtt gtataggttt
    29401 ctggcagacc gctaatgtct ctagttaaac aatcctcaaa tagtgactga tctcttttct
    29461 ttaccgcata aagaatgtct tggtataact gatagccttg gcgtaagttg ggacaagcag
    29521 ctaacagtcg atcggcaatc tcactttcag tcaaataatc tttaaaactg gcacgccaaa
    29581 cccgtttttc atagtttaac tttgcttctt ctttttgtag gagtttccaa tagcgcttca
    29641 attttttccc taaccctcgt tgagagtggg aatttccttt aagtcgtacc gtggtttctt
    29701 tcactcgatg attcaagaaa gttctgccaa tatgttggac gatgtggaaa cgatcgatga
    29761 tcaactgagc attcgggaaa agctttttca ccaacgaaac ataaggcgca tacatatcaa
    29821 taacaatcaa ttgaacggct tcacgagtcg ctaatgaaaa ccgagaaaaa tagcgttcta
    29881 aataaggcaa gcgtcgattt tcgacaatat ccaataatgc atggctttgt ccgtccatca
    29941 tgataaaact cattgcactg gcaacacttc gaaccgattt gaattcatca aagcataaga
    30001 cctttggcaa agtctgtttg aaaggattca atgggcggta gaatcgcttc atgacacgat
    30061 agaccgaaga agtggaaata tttttctgac gagcgatttc cgtcatggaa gtattctctt
    30121 ttaagcgagc aatgacagac caacgaactt tttgactaat gaaacagtgt ttttcagcaa
    30181 cagaggtatc cgctacgaat gttctttggc aagacttaca tttaaatcgt tgtttcttca
    30241 gctccagata agtgcgatac tcagacacat cattcagtaa caaccgaacg gttgtcgtcc
    30301 cccaacgaat gatcctagag gggacgacac aaagacaatg ggaacactct tctggcttgt
    30361 acagaagagt tcctttgtaa atcaagcaaa tttgcccttt gtatttttct ttagttaaac
    30421 aattttcctc gaaatagata tttaggtcta gaatatttag ggtatctttg ataagctgag
    30481 tatgagacat cttgaatcct cctatgaatt ggt
//
LOCUS       DAYNVV010000029        29606 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.029, whole genome shotgun sequence.
ACCESSION   DAYNVV010000029 DAYNVV010000000
VERSION     DAYNVV010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29606
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.029"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..1350
                     /locus_tag="ACGXWR_001508"
     CDS             <1..1350
                     /locus_tag="ACGXWR_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFK0803087.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1484..2827
                     /locus_tag="ACGXWR_001509"
     CDS             1484..2827
                     /locus_tag="ACGXWR_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFK0803088.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            2939..4390
                     /locus_tag="ACGXWR_001510"
     CDS             2939..4390
                     /locus_tag="ACGXWR_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFK0803089.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            4739..5371
                     /locus_tag="ACGXWR_001511"
     CDS             4739..5371
                     /locus_tag="ACGXWR_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HFK0803090.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            5959..7398
                     /locus_tag="ACGXWR_001512"
     CDS             5959..7398
                     /locus_tag="ACGXWR_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFK0803091.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            7693..7911
                     /locus_tag="ACGXWR_001513"
                     /pseudo
     CDS             7693..7911
                     /locus_tag="ACGXWR_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
     gene            8160..8375
                     /locus_tag="ACGXWR_001514"
     CDS             8160..8375
                     /locus_tag="ACGXWR_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803092.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(8592..8848)
                     /locus_tag="ACGXWR_001515"
                     /pseudo
     CDS             complement(8592..8848)
                     /locus_tag="ACGXWR_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9035..9946)
                     /locus_tag="ACGXWR_001516"
     CDS             complement(9035..9946)
                     /locus_tag="ACGXWR_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFK0803093.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(9965..10969)
                     /locus_tag="ACGXWR_001517"
     CDS             complement(9965..10969)
                     /locus_tag="ACGXWR_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HFK0803094.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(10966..13089)
                     /locus_tag="ACGXWR_001518"
     CDS             complement(10966..13089)
                     /locus_tag="ACGXWR_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFK0803095.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(13094..15541)
                     /locus_tag="ACGXWR_001519"
     CDS             complement(13094..15541)
                     /locus_tag="ACGXWR_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFK0803096.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(15528..15917)
                     /locus_tag="ACGXWR_001520"
     CDS             complement(15528..15917)
                     /locus_tag="ACGXWR_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFK0803097.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(15977..16480)
                     /locus_tag="ACGXWR_001521"
     CDS             complement(15977..16480)
                     /locus_tag="ACGXWR_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFK0803098.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(16493..16714)
                     /locus_tag="ACGXWR_001522"
     CDS             complement(16493..16714)
                     /locus_tag="ACGXWR_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803099.1"
                     /translation="MNFGQNLYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFLV
                     IALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            complement(16719..16856)
                     /locus_tag="ACGXWR_001523"
     CDS             complement(16719..16856)
                     /locus_tag="ACGXWR_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HFK0803100.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            complement(16853..18037)
                     /gene="mobT"
                     /locus_tag="ACGXWR_001524"
     CDS             complement(16853..18037)
                     /gene="mobT"
                     /locus_tag="ACGXWR_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HFK0803101.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(18296..18586)
                     /locus_tag="ACGXWR_001525"
     CDS             complement(18296..18586)
                     /locus_tag="ACGXWR_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803102.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            complement(18576..19718)
                     /gene="dcm"
                     /locus_tag="ACGXWR_001526"
                     /pseudo
     CDS             complement(18576..19718)
                     /gene="dcm"
                     /locus_tag="ACGXWR_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            complement(19794..19958)
                     /locus_tag="ACGXWR_001527"
     CDS             complement(19794..19958)
                     /locus_tag="ACGXWR_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803103.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            complement(19951..20625)
                     /locus_tag="ACGXWR_001528"
     CDS             complement(19951..20625)
                     /locus_tag="ACGXWR_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFK0803104.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            complement(20703..20915)
                     /locus_tag="ACGXWR_001529"
                     /pseudo
     CDS             complement(20703..20915)
                     /locus_tag="ACGXWR_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(21036..22895)
                     /gene="ltrA"
                     /locus_tag="ACGXWR_001530"
     CDS             complement(21036..22895)
                     /gene="ltrA"
                     /locus_tag="ACGXWR_001530"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFK0803105.1"
                     /translation="MNKVKTNKTLRHSEYYGMTQIFDELYVKSDKKEVFTELMTIIMS
                     DENIRLAYRNIKNNKGSYTASTDKKSIRDIKTLSEDTFLTEVKVLFRCYKPRAVRRVE
                     IPKPNGKTRPLGIPSIWDRLIQQCILQVLEPICEAKFHNYSYGFRPNRSTHHAIATCN
                     RLANRGKLHFVVDVDIKGFFDNVNHSKLLRQMWTIGIRDKWLLGIIRSMLNAPIVLPT
                     GKVEHPKKGVPQGGVLSPLLSNIILNELDWWVASQWQNTTIETEKIMDRRDKGKGIDK
                     TNQYRALRRTNLKEIYIVRYADDFKIFCRKRSHADKIFHATKMWLKERLSLEISEEKS
                     KIVNLKKGKSEYLGFELKLIKKGKKYVVESHMSKKSMTRVKIQLKKQLRKVARPKNHC
                     EQAKEIGLYNSMVIGIHQYYGIATCVNLDCSKIAYTLKPFINHKLPTKKHGKILNTFI
                     KSKYGKSKEMRWLNNVPIVPLNYVQFRLAVPLSEGTCKYTESGRSKIHSKLKLDLALL
                     LHMMRNSNYERSIEFVDNRISKYSAQKGKCAITGKFLEYEEIHCHHIVPVKQQGTDKY
                     SNLIIIHKNVHALVHAIEEKIIHKYLNVLNLTNEQIEKLNELRVKAGNSVLTV"
     gene            complement(23610..24755)
                     /locus_tag="ACGXWR_001531"
     CDS             complement(23610..24755)
                     /locus_tag="ACGXWR_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFK0803106.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQCATCF"
     gene            complement(24838..25173)
                     /locus_tag="ACGXWR_001532"
     CDS             complement(24838..25173)
                     /locus_tag="ACGXWR_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HFK0803107.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            complement(25183..25557)
                     /locus_tag="ACGXWR_001533"
     CDS             complement(25183..25557)
                     /locus_tag="ACGXWR_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFK0803108.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            complement(25570..25884)
                     /locus_tag="ACGXWR_001534"
     CDS             complement(25570..25884)
                     /locus_tag="ACGXWR_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFK0803109.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(25997..29224)
                     /gene="fss3"
                     /locus_tag="ACGXWR_001535"
     CDS             complement(25997..29224)
                     /gene="fss3"
                     /locus_tag="ACGXWR_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HFK0803110.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVALVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
BASE COUNT         8942 a         5919 c         5211 g         9534 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta
     1441 aagatgaata tactttttat agaaaggaaa agaatgtaat taagtggaaa aaatagtaat
     1501 tattggttca aaccattcag ggctagccgc agctcgattt ctaaacttaa gcgattcaaa
     1561 ttatgaagtt attctaatcg ataaaaaatc agaaattagt tacttggaat gtgggacatc
     1621 gttatttata aaaggagaag taagtaattt agaagatctt ttttatcaaa atagaatgac
     1681 actaaattct gagataaaaa agttatttct agagacagaa gttgacaaaa ttgatattca
     1741 aaataaaaag attagttgtg taaaaaaaga tggtacaaga ttctctcaag aatatgacaa
     1801 agttatatta gctacaggtt caaagcaaat tatgctagat ataccgggga ataatttagc
     1861 taatattttt tcgataaaga attttccaaa tgcaaaagag atttttaaag ctttggatga
     1921 tagtactatt aaaaaagtag gaattattgg agcaggatat attggagttg aaattgctga
     1981 agccataaga aaaagaggga aagaagtata tcttttcgat gttgcagata gagtgttgtc
     2041 gacttattac gaccgtagtt tttcagataa agttgaagaa atactatcaa aaaatggaat
     2101 acatctttgt ctatcagaaa gtcctaaaaa atatttagga agaaaaaaga ttgaaaaaat
     2161 agtcactaca agtggtaccc aatactctat ggatatggtc gtacaagcta taggatttct
     2221 atctaatagt ccaattgggg aaaaggaact cttgagagat gttagtggag catatctaac
     2281 taatgaatac cagcaaacaa atataaaaga tatatatgct attggggatt gtgctacaac
     2341 tttttttacg tccattaata gaagtagtgt tgatttttct atttctaatg ctctaagaac
     2401 agcttatatt gcaactcaac atattaacaa tcaagatttt acaccttctg gttcccaatt
     2461 tacaaatggc ttttctatat ttaattacaa tttttacgca gcaggtttga atttaaaaac
     2521 agcacgatta ttaagtgagt ctatagatta tatagaaata gaagatttca ttagacctgc
     2581 ttttttgaga aaaaatagtc gtgtaaaatt aagaattagc tttgaaaaaa atacaaagag
     2641 aatagtaggt gtacaacttt gtagtcaaga agatttatct ggactattat caatgttttc
     2701 tcttgctata gaagaacaaa ttacattaga caaattgaaa atgttagatt atttatttca
     2761 tcctagtttt agccaaccct ataattttat tttaaaggca gtaacaggat taaacattga
     2821 aacataatcg ttactaaatg aaatcaagaa atatactgta ttactcaatt cattgaaaat
     2881 atttatcata atttttaata gaaaacacta ttaaagagaa aaaagagagg taaatcaaat
     2941 gaaaaaatct ttaaaacttg catcagcagt tatattaatg tcccaactcc ttatagcaac
     3001 acctttccat gtgttggcaa gcgaaaattc aacatacaaa attgcaaaag aaagaaccga
     3061 gacgactgaa atgagtaatt ccgatgtaac agcagagagt agtgaacttt tgacaacttc
     3121 atcaagtgaa agtagtacga cttcaaatgc cgagtcttca acaacttcat caagtgaaag
     3181 tagtacgact tcaaatgccg agtcttcaac aacttcatca agtgaaagta gtacgacttc
     3241 aaatgccgag tcttcaacaa cttcgtcaag tgaaagtagt acgatttcaa gtaccgaatc
     3301 ttcaacaact tcaagtagta caagtgaaat aacttcttcg aaagtgacaa aaccaaacca
     3361 tatagaatct tcaaaaaagg aagcgccaaa aacggaagga caaacaaaaa ctttttcgac
     3421 accacagcaa atagaatcaa cagaatcttt ccaatcacaa ccaatactat ctggtaatga
     3481 agaaattcat tttgacaaaa atgaatctgt agaaaatttt attatgaaaa ttggtgagtc
     3541 tgcgagaaaa attggtcaga aatatgattt atatgcttct gttatgattg cacaagcgat
     3601 cttagaatct gccagtggtc aaagccagtt agctcaggca ccgaattaca atttatttgg
     3661 gataaaagga acttataatg gaaactttgt cattatggta acaaacgaag atttgggtaa
     3721 tggaacgctt tatacgaccc aatcaaaatt tagagtgtat gaaaactatg aggaaagctt
     3781 tgaagattat gccaaattat taactaaggg aattagtgga aataaagatt tttatgcagg
     3841 agcattaaaa gctaatagta aaacatatcg agaagcaact aaattcctta caggacggta
     3901 tgcaacagat acacaatact atttgaagct aaatgaatta attaaaacct acgatttaac
     3961 caactatgat aaagaagtta aaggtccaca aatgagtaag actggatacc aagtgcctat
     4021 tcataattat tcaataacca gtttgtttgg aaatcgtgga aatgaatttc accgaggact
     4081 tgatatggca gctacacagg gtgagccgat tcatgcagtt aaagctggta aggttgttaa
     4141 agcagagttt cactactctt ggggaaatta cgtggtgata caacacgaag atggatcaac
     4201 cgcgttatat gctcaccagc aacaatacct agtaaaaact ggagataatg ttttgcaagg
     4261 acaaataatt ggctatgtag gaagtactgg gaatagtact ggcccacacc ttcatttgga
     4321 aatttgcaaa gatagtagtc tttctcagag catgttagtt gatccgaaaa ccttattatt
     4381 cggagactaa aaaaggtaat caatctgaca aagtaacaag aaaatggttg gattcttaga
     4441 cctttgatca ggatattgag actggaattg atatctcgat tacgatgggt ttgacaaata
     4501 aaacaagtcc attatcgaat atcgagtgta ttattgccgt ctttatgctc atattttgag
     4561 caggtttcac tagatgaaaa caatttatct atcttgagga tttcgtgtac gtatcgttca
     4621 gtcttgtatt gtaaattagt cataaaatca gactaagaaa aattggaaat atttttttct
     4681 gatttattaa aagttaattg aaattatatg gtacttcttt cttgggaggg taggtgcagt
     4741 gaaggaaaga tatggtcacc ttactgttgt tgaggagatt actcataatg gatataaaaa
     4801 atatcgttgc ctatgtgact gtgggaatga aacgattgta tatcgatcaa acttactatc
     4861 aggtagaacc aaaagttgtg gatgtggaaa ttataaaaat aggcataaat ataaaaattt
     4921 gacaaataaa acttttggta agttagttgc aatcaagcca actaaactgc gaagtgaagg
     4981 aactgttgtt tgggaatgtc aatgtctgtg tgggagaaaa aagttagtat cggcaaagcg
     5041 acttctaaaa ggtgatgtaa aaagctgtgg atgtttgaaa tcaaaaaagc atcacattga
     5101 aaataaaaaa ttcggattac ttactgcaaa gtatcctttg gacaataact gttcatggaa
     5161 aacaaaatgg gtttgtcatt gtgagtgtgg cagtatgtgt gagataagtt atagtaactt
     5221 attttttgga catactcaaa gttgtggatg tttaaaaagg caagaaacaa ggacatgtgt
     5281 tgaagggaca gtaatagagt gtctaacgtc aaaattaccg aaaaataata caagtggtgt
     5341 taagggagtt tatcgttcta aagagaaata gattgcgtat ataactttaa aaaaaaagag
     5401 gtactattta ggatcgtatg attctattaa gagtgcagct caagctagaa aagatgctga
     5461 aaataaattg tttcaacctt tgattgacaa atatcgaggt aatcattaat tattgtggat
     5521 aataattaac agtgatatat aaacatctat aatatattat tcatactatt gatatttagt
     5581 ataatcctat ggaattgaat atcatagcaa tgtatttgaa aagcaaattg gaaaacaaat
     5641 aggtgcaaca ccataaatat gaaaaaattg ggaaaaagta gaatggaaat ttgcttacgt
     5701 ctcacgagat agctcacact attaatctga agaacaatga agtcgacttt tagaaattgc
     5761 tagaagaaag taaagcgaat tatcactagt tactatagag taagttcaaa taaagcatct
     5821 ccaacttaca tggttacatg aggatatcaa atcgaaatta ctcaagcttc ctatggctag
     5881 agtcgcgaga agttgttggg cagtagacat aggttatatt gttcttagct acacgatcat
     5941 tagaaaggaa atcctattat gtatagttat caagaagatg caaaagtcca aaaaaatcgc
     6001 tggtggattt tgattgctat atctatgttt accttcatgt ccacattgga tggcagtatt
     6061 gtcaatattg cactacctac catctcagat gatatgggca taccaatgaa tcaagcggaa
     6121 tgggtagtgt ccgtttatct gatgattgtc tgttcttgtt tgttgctgtt tggtaaaatt
     6181 ggcgatagcc gtgggaaaat caaagtattt cggattggta cgctgatctt tgtcttggga
     6241 tcgctgttgt gtgggttcaa tcattcgcta ggtattttat tgttcgcacg ggtggtacaa
     6301 gccattggtg ctagtatgac tatggctaca aatgccggaa tcatcacgga agtctttccc
     6361 atacatgaac gtggtcgggc attgggagca ataggtgcgt ttgtttcatt aggctcgatt
     6421 gctggaccag gtcttggcgg cttgattttg tcccaatttt cttgggcgta cattttttgg
     6481 atcaatgtac cggtgggaat cgtaacgatg ttgattgctg aaaaattctt accaaaagat
     6541 atcaccatga gcggccatac aatcgatgga gggggctttg ctgccattgc ggctacgatt
     6601 atcagctttt ttggagcaat ctttttgggg caagaaagtg gctttttcca tccagtcccc
     6661 cttgtactgt tcgtaatttc agtgattgcc tttgtcagct ttttaaaagt tgaaaagaaa
     6721 gcagcctctc cattgatttc tttcggtatt tttaagaaca agatttttac catgagcttg
     6781 attacagcct tgttgatttt ttcttccaac ttctttgtca atgtagtgat tcctttttat
     6841 ctgcaaaatg ctcgcgggtt gagtcctagc tatgctgggc tgttgatgat ggtctttcct
     6901 ttgatgatgg tcgtcggggc gcctttaagc ggctacctga ccgaccgggt tggcccggag
     6961 attttggtat tagtaggctt gggcttattg tcggtaaccc aggtcatgta tatgtttttg
     7021 tcagtggact ctcctttgtg gctatacatt gtcgctactg ccatcatggg tgccggcaat
     7081 gccttgttcc agtcccccaa taatacgatg gttatgagct cggtcactat cgaaaacttg
     7141 ggactggcag gctcgatgaa ttcctttgcc cgaaatttgg ggatggtcag cgggatttcg
     7201 ctttctacga cggtcttata tcaagcgatg tctgctaaga tgggccagca agtaactaac
     7261 tatatcgcaa atcggccgga tgtcttttta tatggaatga agattacctt tttaggcagc
     7321 tttgttttgt gttttgttgc ctttttcctg actatctggc gtatcaaaaa acaaggaggt
     7381 attcagaaaa atgtctgaaa aaaccactgt tgaagaattt ttggaggcct gcgtatgggt
     7441 gagtgggatt tccatggatg atggaagatg aagtgaactt ctaaaagccg aaaaactcaa
     7501 gtattatctt caaaatacta gtgctcaatg agatgcttga tttgatcaca agaagactgc
     7561 gaaagccgct ggcaaccgca agctaggtat cccaccgatg gactacgttt tagaggctac
     7621 tggttatgaa tacggagcca acgctctcat ctgcataaga atacatcacc cagattatgt
     7681 aaagattttc gatacttctg tcaaaaaatc attaagatag ataaatgatt tccgtctagt
     7741 caaattggtt cagaatgtag acacacagat ggtaagaagt cactcacaat tcgagaatgg
     7801 acttgtccta tttgccgtat acatcataat cgaaacgtca acgatagtat caatattttg
     7861 accaagggct atgaatacaa gcattgcctt agaaaacatc aagaacctta ggaacaacgg
     7921 ggatagcttg gttaataaga gataccgctg tttaggcttg caagtatact cttttatcaa
     7981 gaattccgtg gctttagtca tgagaggctt aatactatga aaattttctt tagcattttt
     8041 gatttaggtt ccttttctaa ttataataag atgaccacta cagtaaccta ctgaaatata
     8101 taaacagcca ctgtagtacc attttcaaag tagtctatga gaggagaatc ttcattctta
     8161 tgaacgctgg aattgcggat atgaatttaa taaaaaaaac ccttaatgat tttacttcca
     8221 attcaatatc aaaaggtact ggtatcaatt taagcacaat aaaaaagctg aaaagtggtg
     8281 aaagatcagt ggaaaagctg aatcttttag atgctataaa aataacggaa tttgctatga
     8341 aaaatggaaa agctgagatt gaaatatgga gataattatc gtctagtgaa ttacttgcca
     8401 cttagctgaa tttaacgatc cttggtgctt gaagggggag attcttggga atagagcata
     8461 cttgcaagcc tatgtcttta ctaacaacga tatctcttat taaccaagct atccccgtag
     8521 ttctaaggct tttactttta tctaagcaat aatcgtattc aaaggaaatt tttgaccctt
     8581 agaaagtctc attttatcag acgtgagctt aggcattgct gaattttgtt aattcggttt
     8641 taggttgtgc tttgagcata atatgaaagt attctttatc acgatttcat tcatctaagg
     8701 taatgtgatg tgattctgaa attctttcaa aggcagtttt tgcataagct gacattacat
     8761 catcaatgac atgtttacaa tgtttcacta ctaaaataag ggggtaacca agaagaaaaa
     8821 ctgaatgatt atttgtatct aattccatgg tatatcaacc atttcctata tagactgatt
     8881 atgacatgga ttaaaataaa aaggcactat gtcttaattg tcggttttcg agttaccgaa
     8941 tggcattcat cacccaccta tagaggatgg gcgacttctg cctgaaataa gttacactac
     9001 ttataacttc taataaaatt agattgagtc attattattt aacatcaacg attttccagt
     9061 ttccattttt ttgtaatact aatttgtact gaaagtagct agtggttttt gatacattat
     9121 caaggtattt tatctttgta ctcactagaa aattttttcc gttttgtaga taaactggat
     9181 tctctaactc cgaaaacttt aagtcaatat tgattggtcg catcgcacca ttttcaacat
     9241 aatactccaa ttctttttca gaagctgatg gataaagttt aaaaaatgtt tctaaaaaat
     9301 cggtgatttc ttccgttgtt ttggcatcaa tttctgaatc gttttctact tgttttgctt
     9361 catattttgc cttgtctggc tttccaatca ttgttggcaa actagttact aaatgattcc
     9421 tgttttcatc ttcaaagatt gtcactcgat atgcagaaga aattgattgc gtcttttttc
     9481 cctctgtaat atgttgctcc actaaaaatg aaacgacaaa ttcttccgag tgtttttcaa
     9541 catctagaat ttttacagat tgaacttcgg aactcgtggg aatatctgct cgaaccatat
     9601 cttggattaa agcgagaccg ttttctgtaa ggtactgttc gagattactc attctctttt
     9661 caattgcttc tttgttattt ttccatgaaa aatattcttt cgcaaaatcc tctgtaaaac
     9721 tttcaacgcc agaagtattc actaccttct cttttataac cactttttca tgagttgtat
     9781 gttgatcaat ggcggtgaaa tttttataaa cgccaaaagc aagactacaa gacaataaaa
     9841 gccaaagggc aagcaccatt tttcgatgct tacccacgga tacaactcgt tcttttttct
     9901 tttttgggct cttttccttt tgattccgtt caatttttat cttcattctt tttcctcttt
     9961 tctcttattt gtatcggcca gctccgataa gatgctgccg ccaatagttt tccgttagat
    10021 tcgtccaccc cactggatct cctgcatgaa acatgcgatt ctcccctgcg taaatgccca
    10081 catgggtcac ataagtaccg gcatcatagg ttgaatgaaa gaaaactaaa tcacctggtt
    10141 tggcatcttt tagatcaata tgagtcatgg catcatattg atcctgagcc acccgaggaa
    10201 gtttcaggtc aactttggca taacaccatt gggtcaagcc actacaatca aaccccgttt
    10261 ctggacttga gccaccaaac acataggccg ttccttcata cttaaatgcc tcatcaaaaa
    10321 tttcttggac tattttgtca tcaaactgag ttgtagttag gtattgcttc actaataaac
    10381 agtaaaacat attgccataa ttataccgcc acccaccatt ttccttaatc gcgattgggt
    10441 tggggtaatc gactttttga ccacctgatt tttcctttga aaaagattca gctaaagcaa
    10501 aactatgctt cttcccgttt ttcccgacat gatctagata cccgccacca tagttatagg
    10561 cctgaataat actatcttga tcacacccta gttctttgga acgcttaacc aaagacgcaa
    10621 aatagagaca gccttgtttg atggatgcct cggtacttaa tgaattaggt ggtaatccgg
    10681 ctgactcaga actttgcata acgtcttcca ttgtgccacc agattccact tgaataatcg
    10741 ccaaaagaat tggaatatac tctgttatat ccgattcttt ggcatacttt tccaccattg
    10801 cacggtgttt caatacttct tctgagacac tagttccgcc aggagaagtg ccagaactac
    10861 catttccctc actgtcttca ccaaacaaca aacccacaca catcaaaata cccataaaag
    10921 agatggtcag aaaagttaat gaaataacac ccactttctt caagttcatt ttttctcacc
    10981 tgaccttgat tttggacgat ggttcattct tttttgtact ttttgattgg tctgctttgg
    11041 cagagtggac ctctgtttca cttgttggaa agaatttttc ttacttgctg attggctttt
    11101 cccttttgaa atgatttctt gactagttag ttttcgtttg atttcgggat tcagatttgc
    11161 tctcacaatc cgctttggtg cttctttttt cagcatcata tctttctgag gttgagctgc
    11221 tttatctatt ggaatattcg cccttctttt tccctgacga tttgttgctt cactcagtat
    11281 cttgcgtttt tcgtccattt tcgcatttct tcgttgtcgt tgtttttctc gcaaatccac
    11341 tcgatccgct ttttcttgga acagtccgcg cttgaattct tctggtgctt ttttcgactt
    11401 ttcgattcct ttatggagat tgtatttcaa attcgttggc gtattcctta cctgatcctt
    11461 tacttgttta gtcttatctt tcaccaaagc ttgggtatcc aaaactttgc cgatttttct
    11521 cccagccaaa ttcattcggg attgtttctt attatttgaa actggattct ccttagttaa
    11581 gtcagatagt atttcgtgat cgttcggtaa tcgtgaattc tttcgtagag aagaaccgga
    11641 tggcttaaat ttggattttg attgttcctt tgccaactta tttccgactg ctgcaccacc
    11701 accaaaagcc aaagctcgtc ccacatttcg attgagttgc cgcaattttc gattcattaa
    11761 catttgcggt tttcgcatga cgcgtcttcc cattgactgg ctatcattac tctggaggtt
    11821 gaacatactc ataatgtcgc ccaatttgaa atagataccg gcaaaggtca caatttgcag
    11881 aaaagcaacc atgaaaaatg gataggttgc cgaaatattg aaaaacatcg tggagatgct
    11941 aaatgcagtc gtaatcacca aagtaacacc cgctcgcatc ataatcgtat tgaataaacg
    12001 aataatcgcc ttctttccta aactttcata agtcggcaac atggacaata agaaactaat
    12061 tggcagaaac atcgcaaaga taatgaagag aatttgcgag aacaacataa tccctgttag
    12121 aagaaaaaca aagaaggaaa tgccaatatt gaacaatacc aaaaagacca cggtccctaa
    12181 acggttcatg gtcttggtaa tactgagatt cgcattgtca ttgtcttcaa tctctgcctt
    12241 gaccgcttct tcccgatctt tgcctttgtt ttcatctgga ctcacagata gaatcttgtt
    12301 gacccggtct tcaccaattt cttctatgtt ggaatcatca aattgcagta gtaaccaagg
    12361 ttgttggact tgaatcgaaa acaaactatc ccgaatcaaa tccacactat cttttccttg
    12421 gctttctgaa ttgggtacaa cgatctcggt tccaagggta agggccgctt cactaacatc
    12481 tgagctaaag tcattgattt ttgtgatata ggtaggcgca taagcaatga acgaacccga
    12541 tagtagaaaa atcatcacaa aattaatcac ggctcgaact gctttcgtgg tttctcgttt
    12601 taataatccg gtatacgcca catacacccc cagagctaaa atcatcaata atagaaaccc
    12661 aaaataaaat ccggaggtct ggagtccatt ttcagtaata ccagccaatg tttggatatt
    12721 ctttccaata ctttcagccg tatccgaaat gaaatctaat ttgtaagcct cttgaaccac
    12781 ataacccgtg gcgttcgaca aatacaaact caccgtccaa atgaaattag taatggcata
    12841 aagaccatac atcacgcttt tccctaagcc atcaccccaa ttccaaggca accaatccca
    12901 agagctatcc acaaagaaat ctagttgata gttgttcagt gaatatttgg aatatagatt
    12961 tcctgcttca actgtatcat caactagccc tgtcgcctcg gctaccgtac caactaaact
    13021 caatagaact atcagagtga gtatgctaat aaaaacgatt cccacaatcc gaaaaagttt
    13081 ctttttcatc ccctcactcc attctctctt gaacaggtgg acgggtatca aaggcatgga
    13141 agagttcttc aaagactgga tgtacctgaa ccacgcctac ccgaccatac aaatcctgca
    13201 tcaagcattg gccattttcc aaatctcgta ggcgtttttg attgctttca tcttctcgat
    13261 ccaagccaaa gaattccaag gttttcttga tttcatgaat atcggtactg cgaaacgcaa
    13321 acttcaaccc gatattattc ttcaagcgtt catccagtaa atcatcacta ttttgcgtga
    13381 caaagtaaac cccggcattc atagcccgcc cagcacgaac gagcttattc gataatgttt
    13441 tcccttgcgc tacttgaaga aaactccacg cctcatctaa gtctacaatt ttgaagattt
    13501 ctcgattact atggataaag tccaaggcaa aagtggaaat gacgattagc atggaaacac
    13561 taagcaattc catggtggta tattcttcaa aagtggtttc tgcatctggt aaaaccaaat
    13621 ccgctacttg aatgatattt aactgcctat ctaaactaat cgactgggta atcgaaccat
    13681 ctgagaaaag caaatgggca aaatcataat cggtaaagga ctcgatgtga tccgcgatat
    13741 tttccgcaac tggtgagcct tcttttcgaa gctcattaat tacttgtaat aatccccgtt
    13801 gattgctttg ggtaaccgtc cgaatggcct tacgcaacac tggaaacttc tccccatctc
    13861 gactagaaat tcctgttaaa aaggtcagaa tatcaattgc tagactttca gaatccttct
    13921 ttttctccat aatcacataa ggatcaagta atccttgatt ttttggctta ctagttaagt
    13981 tgagaatatt gatttcatcc gcaatttctg gcaaggtttc tttccagcca ccccgttccc
    14041 cttttggatc gacaatcaca gcttgtccac caaaaaggac ggcgtaataa actaagagat
    14101 tgttactaaa ggactttccg ccaccgagtg aaccgaggaa tgccgctgct agcgcattgg
    14161 taactgaacc cttgacccct tgtgaggcca atgccggttt caggtaaaca ttgcgccccg
    14221 tatctacgtt ataaccaaag taaatgcctt ccaactcccc taacatctga gtggcgccaa
    14281 aaccaagtcc ggcgagaaaa tcagacgtaa catactggat ataatcattc atgtatcgct
    14341 tactagaagg taagaattct tcatgtagcc ccatcatatc gccaaaaggc cggactagtt
    14401 ttacattggt atcatcataa aaatctagca cttcatcaca ccggcgcttt agttcatcta
    14461 ctgattcggc acttactcga accacatagc tcagtttgta catggattct ttggactgat
    14521 ccaaggtagt ttccaattca tctacggaat ccaatgcatc taagacattg gaatttgttt
    14581 cattgtcaga ttgataggca tggttgtcca agtcttttaa ttcctttttc ttattgcgaa
    14641 cggtagcaag tgcctttttg ttcgtcacaa tctccacatt catactagtg tcaattggga
    14701 atgtaaattg ttgttgctgg taatagaaaa gttctgagga gggaaactcc atttccccca
    14761 caattgtatt aattgttaag tacgctacat atgattcatg attctcatgt tccatgcata
    14821 agtaccgggg cttttcttca atcaaacaac gactgggacg taataagtcg taacgtttca
    14881 ccaaagtttc cgacttcagc tttttctttg gtagctgaaa ttcatattct tcaaatggtg
    14941 tacccttttc gccatagata tgttcaatca aatacatcag atcactcggt gtgactcgtc
    15001 tgactttaaa tcttcgagcc aatttacttt ccattagttt ttcaagcttg gtatatcggc
    15061 gaatttcttc attggataag gaaacaaaat cgcccatcaa atgatgattc actccataga
    15121 caaattcttg aaagccggag aagaaagatt tcttgagatt ctttagattg acctcttcat
    15181 ctgtcgcaat cagtttgaag ccaataaaaa agcgataatc aatctgacta tcgccaatca
    15241 tggatactaa tgcctctgtc tgtaaatcaa ttcgttgttt cgctacttct gttaatcgcc
    15301 cggtaatttc cttttttgat cgttcttgcg tggcacgaat actactttct gtggcaattt
    15361 gtaaggcatg aatcttgcct tcacgatttt gcgcaatcaa ttgacgaaag ttatcgtgga
    15421 cttgatattt ctgttcaggt gacaaaaagg agtaattgta aggtattaac tcatagtagg
    15481 caaaacattc tccctcttga ttaaagacaa gattattttc aatatactta atcgggtaca
    15541 tagttcacac tccttaccag agtaatgggt tcgtcccatc gtttcttctg ttctttgact
    15601 ttctttcctg cgaaagtgac cttaaatcgt aagtgatagc taataaaaga tcgtaaaaat
    15661 cccaatggtt tcttaccgtc aaacgttttt tgcgacatga accaagtaac tgccaccggt
    15721 atacctaagt attttaaaaa ggccccctct atcatagata gtggaggcac atgggcaaat
    15781 acgatgacaa acagcaagga taaaacaaac caagccatct ggttaaaagt cacaggaaaa
    15841 ggcagttgaa agtcattaat tgcataaatg accttttcaa ctgcccaaat actggtgtag
    15901 ctttttattt tcttcatcaa atcattcctt taaaaagaag gatagtttag aaatcaacta
    15961 cccttcaata attttgttaa tatggatact caaaaacacc tcgactcgtt accaaataat
    16021 tgcctccaat ctccaagtct ctaccacacg catcaaaatc aatatacgtc ttcaagtgtt
    16081 ctggtacttc tccaaaatca ccagcttcta caatcaagaa atatgctaca tcactcatat
    16141 catcgcaatc tggataatag ataatatcat ccacatgctc taccatctcc tcaaaagaat
    16201 tgaagaaagc atgttgaatc tcagaagcaa cttcaccaac tggcgttcct tcaagttcct
    16261 ccgctaagcc acacaaccga ttaatttcct caattggcgt atactcatca atctcaaagg
    16321 gaagttcata atcatgaatt gcatattcct cgtattcgtc atttaaccca attcgttctt
    16381 tcacttcatc aaaatcgaca ggtggggtaa accacgcccc caccaattca ccttcgttat
    16441 atttcccgag gttcgcaata taaacacgca tctgttccat cgtgcttccc ccttacgcac
    16501 cgacaattcg gttaaacaaa ctgagtaaga catccttcac cccagaagca ttaaagacca
    16561 atccgaccgc aatcaaagca atcaccaaaa agccaatcag tttggaaaac tcccgcttaa
    16621 atcctaaaaa caaaccaatg accacaattg ccagtaagac taaggattgg gcattggtta
    16681 aaaaccattg atataaattt tgtccgaaat tcatcttgtc actttccttt cttttccatt
    16741 gctcgatccg ctgctgcact tgcattcatc aagcacatca cagtaacacc aagcatactg
    16801 ccaccaaata ccaaaaaaat atcttttaca attcccatga cgattcctct tttcatataa
    16861 tcaaattttc aattgccata ctttgttgct ccaaaatctt tttatgtcgg tctgataagc
    16921 gtgcattctg taccatatcc tggatatagg ttgtccgatt caatcgatcc aactccttag
    16981 ccattttcca cgtaggggcg acttgtcggc ctagccaatt caaggttcgt tcaatggtat
    17041 acggttttgg ctcggaagtt aattgaatct ctttccgatt ccgtccaata aaacgccccc
    17101 attgttcatt caagggccag ttggttcgcc ttttaccttc tactttatcc gcaaatcgca
    17161 agtaacgatt gataatggaa aacgtggtgc tctcaatgct acgacctttt aacaaatctt
    17221 gaatcgcatg aaaagcacgg tcatttttca gtcgaatctc aaaacgattt ttcgtctcag
    17281 tttggtctaa tggaatccct aacttgatat attgttcata gtctttttca tacaaacaga
    17341 aataaacctc actcttgaga ctgccgatat ataaggtatt gcccatgccg tccttttcat
    17401 cagcctttaa aagttccccg gaacgataac ttttaaaggt acgaaacaag gagatacatt
    17461 cttccttctg acattttttc gttagctcag gtatatccaa tagccccact cgatcattga
    17521 ttgccaagtc caagcgtttc atcacgccac cggcctttag acaatcctcg aaaaagtcgt
    17581 accagctacg cttttgagcg agtaaaaaag tttcaaattg tcggcaacct cgccccttta
    17641 attctaaaag cacaccttta tcttcttcat gagacaacat caccacaata tcacccatga
    17701 catactgttc ttgataggag taaaaggcat aatcttcatg gagcatatac tcaaatttca
    17761 aatggagaat ttcttgaata atttttcgtg catccgttgt gggaaagcga atccttacat
    17821 agtcaaacag taacgtcaaa ggcaaatcgg gattaaagct ttccagttgg tcaaaaattt
    17881 tcctcatggt ttttatagat gcggttacgc caccattttc tatctgattt aagtacggcc
    17941 gactaagtcc acaagccgta gccaatttat tttgtgaaac gccgtattcg ttgcgtcggt
    18001 cttttaatag ccgataatct aaattccgtt gtgccaagtt ctcacctcca aattcaaggt
    18061 gttaactttt tcaaatgagt taacacctat acaaattact tactatcttt gatacaacaa
    18121 gcattcttaa tggttgctta cttatttttt gtgtttttgt acccccctgt tagatacggg
    18181 ggtgagacat catggtcggc taacgccgtc catgaacagg cacagcacca cggaggattt
    18241 ctgcttcgcg aatcctccgc ggtcagcgcc taacagtcag ttgtgttggt ttaggttact
    18301 catctgtaat accatttact tccaactctg ctttcatttc taacaagtat tgacgaatat
    18361 ctggttcttt tgcttggtcc gcaatccgct caaattctgc aattacttga tttatttcaa
    18421 ttcgagcatc cgtctcctca ttcattaaat atggatcgcc agcgactttg acaccattct
    18481 tgcgaatatc aaattttaac cgtcgcaatt gttcttctaa ttctgggtct gactgaatct
    18541 ttccaatcac ccaataaatt tctccaatca actcatcata aaccatgtac atccaactct
    18601 tttaatcttc tggcaatatc aaaaatgacc ggaactgtta cagagtttcc ggcttgctta
    18661 tacaactgac tatctgaatt gacttgagaa tctcgatcaa aagcccaatc gggaaagccc
    18721 tgaagtcgcc aacactctct aggtgttagc ttccgaattt gatactgatc cgtgacgatc
    18781 gcttgttggt ctcctgttag taaggtatga acactctgtt ttcccagacg acctcggcga
    18841 cttgtggaat taggaaaagc cagattcaca ctgtcttctg gcttcacctc ttgatattct
    18901 gtttcatttt ttcgaatcat gatttttgta ccaccttgtt tcgttgacaa ggtgggggcg
    18961 gttccagtaa cttcataaac tcgattacct tgttcaaact ttcccggtaa tagtcctgct
    19021 acagagattc catcccttgc tggcagtgcg attttgattc cttcatcacc tgttaaggtt
    19081 ggcgctacgc catctgaacc atagacttgt ccacccattc ctcgattgga aggattgata
    19141 tttaccaaat ttctgatgtt ttgatcagat gttgaagacg gtccaatgat aggaaatact
    19201 tgttcggtac atgcgtctcg agaatgtccg ataaggaata tccgctcccg gctttgggga
    19261 atgtaggcct ttgagttaag cacctaccac tccacgtcat accccaatcc atccagcgtt
    19321 cggaggatcg tctcgaacgt agcccctcct tcgtgattga gcaatcctcg gacgttctca
    19381 aggaataaaa gcttaggtcg gagaagagtg gtgaaccgag cgatttcaaa gaataaagta
    19441 cctcgagtat cggaaaatct ttgccgcttt cccgcaattg aaaaagcttg gcacggaaat
    19501 ccgccgcaaa ggatgtccac tggtccgagg gattgaataa actcatctga tacacttgtg
    19561 atgtcatgca tttccacctc cttacttgta tcatgaattg ctttataact acgtctagca
    19621 aatttatcaa tttcacaaaa accgatacaa tgatggctcg cctgttccat acctaaacga
    19681 aagccaccaa taccggcgaa taaatctaaa aatctcatac attacctcat tcattgcaaa
    19741 gaaaaaagcc aagaacattt tgctcttggc tcatacatta ttaatttgtc ctactatttt
    19801 ttatttaatc caactaattt ccgttgtttt tcattggcct gatcggctac atatttaatc
    19861 accgttttga actcttttgc agtagcattt tccgataaat ccgcaatgct cttattgtat
    19921 ttctttacaa ttttcgttac ttgttctttc tcagtcatgt aattgaacct ccaaatcttt
    19981 cctactatac cctagtggta aaaataattc tagattatcc gtagcataat gaacttcgga
    20041 aatattattc gtataatctt ttattatgat atgaagcaat acatctggat gtttactctt
    20101 tacttttgca atgttctctc ttgatttgaa aaaagcgtta ataaatgcct ttttcggcac
    20161 atgacgtccc tctgcaattt cacgttcttg tgtaaatttc caagcgattt tagggtcttg
    20221 ataaacatag aaaatcgtca ctcgaaaatg ttttttcaac gcccgcgaga tatttttttc
    20281 agcacttaat attgcaaaag ttgcatccag aataaaagaa tagccatgat ctaagacata
    20341 tctaaatgcc tgctctacca accaagaaga tgctttttga aagagactag agttttttcc
    20401 attataatca ggaaactggg tgcgaaagta atccgcatca ataatcacat ggttatcata
    20461 attctcagct aatccaatgg caacctctga ttttccagcc ccaggactcc ctgccataaa
    20521 aactgcgtct cgtccaactt cgggggattt ccctttgata atataagaaa taaacttatc
    20581 cttatttgct tttgcatact ctaaataaga atcattactt tccatattaa ttatcccctt
    20641 tcttcctact atataaaagt attatacgtt acttgaagta taaagtcagt attgaagatc
    20701 actcaatcat tcatcttttc taatttacta attgaatcta agaaatcata cccttttggt
    20761 acaagtggcg tataaaactc actaatcaca ctgccacctg tatccacata acctcgacct
    20821 ttgatgtgct tcataaagaa gtttttttcg acctccccaa acatcatgga atatccgagt
    20881 tcactcatac gacccaaagc cacgcgaaag ttgaatagcg ataggtaatc ctttgatgtc
    20941 atctccagat tttcccccgc ttcacaccgt acatgaaact ttcacttcat acggcgttcc
    21001 atcaaaagaa tgttaagtat gatatatttt tcaagttaaa ctgttaaaac actattacca
    21061 gctttgacac gtaattcatt tagtttttct atttgttcat tggttagatt taatacattc
    21121 aggtatttgt gtatgatttt ttcttcgata gcatggacta atgcgtgaac atttttgtga
    21181 ataataatga ggttgctgta tttgtctgta ccctgttgtt ttactggtac gatatggtgg
    21241 caatggattt cttcgtattc gagaaattta cccgtgatag cacattttcc cttttgagca
    21301 gaatatttag atattctgtt atccacaaat tcaatacttc tttcataatt actatttctc
    21361 atcatgtgaa gtaaaagggc taggtctaat tttaatttac tgtgtatctt gcttcgtcca
    21421 ctttcagtgt acttgcaagt tccctctgat agggggacag caagtctaaa ctgaacatag
    21481 ttgagcggta caattggcac attattcaac catcgcattt ctttactttt tccatacttc
    21541 gatttgataa atgtatttaa tatctttcca tgtttctttg tcggcagttt gtgattgatg
    21601 aacggtttta gtgtataggc tattttactg caatcgagat ttacacaggt tgcaattcca
    21661 taatattgat ggattccaat caccatagaa ttatataatc caatttcttt tgcttgttcg
    21721 caatgattct tcggtctggc aactttacgt aattgtttct ttaattggat tttaactctt
    21781 gtcattgatt ttttgctcat atgactttcg actacgtatt ttttaccttt cttgattagc
    21841 tttaattcaa atcctagata ttctgattta ccttttttga gattgacaat tttggatttt
    21901 tcttcgctaa tttcaagtga taaccgttct ttaagccaca ttttcgttgc gtgaaatatt
    21961 ttatctgcat gacttcgttt tctacaaaag attttgaagt cgtcagcata ccgaacaatg
    22021 tatatttctt ttaagtttgt tcgtcttaat gcccgatact gattagtctt atcaatgcct
    22081 ttgcctttat ctcgcctatc cataatcttt tctgtctcaa tcgtggtatt ttgccattgt
    22141 gaagcaaccc accaatctaa ttcattcaat atgatattag atagtaaagg ggataggaca
    22201 ccaccttgag gtacaccttt tttagggtgt tcgactttac cggttggtag gactatagga
    22261 gcatttagca tggatcgaat aatacctaat agccatttat cacggattcc aatcgtccac
    22321 atttgacgca aaagtttaga gtgattgaca ttatcaaaga atcctttaat atcaacatct
    22381 actacaaagt gtagcttccc cctatttgcc agtcgattgc aggtagcaat cgcatgatgt
    22441 gtggaacggt ttggtcgaaa tccataacta taattgtgaa atttagcttc gcatatcggt
    22501 tctaagactt gtaaaataca ctgttgtatt aacctatccc agattgatgg aatgcccaga
    22561 gggcgtgttt ttccatttgg tttgggaatt tctacacgtc taactgctcg tggtttgtaa
    22621 cagcgaaaaa gaactttaac ctcagttaga aaggtatctt ctgacagtgt tttaatgtct
    22681 cgaatacttt tcttatcggt actcgctgta taactgccct tgttattctt gatatttctg
    22741 tatgctagtc gaatattttc atcactcata ataattgtca tgagctctgt aaaaacttct
    22801 tttttatcac tttttacata cagttcatca aatatttgtg tcatgccata gtattcacta
    22861 tgacgaagtg ttttatttgt ttttacttta ttcatagcac cactaccttt gtttacttag
    22921 gttgtagtgt ttattttgtc ttactcgatt ctatgaaata catcatttaa ttaacgattt
    22981 cttttgacta gtggctattc ctccgatata tttctatatc ctcattggta ctgtgccacc
    23041 actttcactg gcataaatgt gcttattatt cttcgtcaca aatgtttcaa tggaatatag
    23101 tttcctccac attgccagct tcccatgttt cgatattttt atctttatat atacttttag
    23161 gtgcttgctt tgaacctgta tatttccaat gcctgtaaca ttgcatggtt gttcataacc
    23221 aataatctta ctaaaccaca acatacattc tgttccgttg atacggtaga atcctgtaca
    23281 tttctataca gtccgtgtat agattctttc attcgcaagt tcgtcagtag tattacttac
    23341 attctcaccg tgagtatttt atagacctcc gacctatagg ttacatcatt cacctctgaa
    23401 caactttcgt atatgaattt atcatattta cggtaacttt cagccgactt caccgagctt
    23461 ctgaccatct aacagctata tgttaaacag ccagtcggag tattaaggga gcgtttcagg
    23521 gcgttacccc atcattccac tgctcaaaat atcagttctc cttaaaagga aacttatgtt
    23581 ttcttctttt aagtgcctaa ccttttcagt tagaaacatg tcgcacattg atcgcggatt
    23641 ccgtctccta aatatttcgc atccggcctt tggcaagcca aaatcagaaa gaaaccagat
    23701 tgacgaccca acatcacgat ttgtttgagc ttattcaaaa tcaccgcact ttctttcgtc
    23761 gttaacatct ccatataagc cacgtattca tcaaagatta aaaagttggg tggaagtcca
    23821 agataggcat aattctctcc tgttttgtag ttagacattt ctttcattgc cttgctacga
    23881 gccatcatac gttcatagaa atcttccaca caagcagaaa tttcttcctt ttgtgaataa
    23941 acatgaggca tcaccgtacc taaatcagct aaatctgcat ttttgggatc gaggataaac
    24001 aattctgcat ctgacttcaa tagtgcttcg ataatggtga ggaggaaata ggtcttccct
    24061 ccacccgtgc caccagcgat taacatatgg ggtaaagaat cataagccca tacttgattt
    24121 ttcatcaatc gcagagtccc attttctgcc actacttcgt ctatcccaat tcgattggcg
    24181 atcatatcat acagtaaagt atactccaca taggagtctt tgagttcctt ttctactaac
    24241 tcacaataca gtccgctttc taacttcttt tccaatttta aaagctgatc ttggtatttc
    24301 ccaagtgaaa tttgaacgcg aatagacagt aatccatctt tcattcgata atagattttg
    24361 gggaagtaac tgatagtctc tctggttcgg ctactattca aatctttgaa aaagccttca
    24421 ctttgagttt gtttcacttc ataccaatgg ttctctagaa tcatccgagc tagcttttgt
    24481 cgatgccaca agcttcgcca atgatcaaga aaaaagtgaa tataaagcaa tatcatagct
    24541 cctgaaaaag cgagacttcc aagcagacat actaaatctt ttatagacca aacgatttca
    24601 atagtagaaa gtgatagctt agaaatatca aattgtctaa actcttgaaa ataaaagacg
    24661 ctcatccaac cgatgaacag agcgagtagc cagccaagaa caaagtgata aaccaagtgc
    24721 tgatctcctg cgcgtatgcg atgtcctttg tacattttga tggtttccac ctccaatcga
    24781 aaaagcccaa taggatttca ttaggcaatt tcaaaaagtt atgctagtca tttactgcta
    24841 cgaggagggg agttgtttcg tttcaaccaa ttgatttaaa aagccttcaa tagcatccgg
    24901 catctccaca ccaatttctt ccaaaatgga ttctgcctgc cgacataagt tttcatttac
    24961 ttcgacaact ataaagaaag actcttcttc tcctaaccag tctagtacat cagagtcttc
    25021 ttcactgtcg ctattttctc caagtaaacc ttgatgtata atcagaaaca ttttttcatc
    25081 agaggttaat gctttaacga gttgttcctc agtcagctcg ccttttccat attgatcgag
    25141 acaatctaaa atatgttcaa cattaatttc cataatcttc acctatttct ttctttcatt
    25201 ttggttcgta ggatttcctt gattcggctg ccgcttcaag actaaatcat ccgccttaat
    25261 gaaccaatta acggtagttc cttctcgaaa aacataattg gcaacggtat ccacgattgg
    25321 attgaccaac tctacctctg catcataagc aaactcgcgt aagggtacat tagctgggat
    25381 actaacttga atcattcgcc cttgtgcaga ggattttaaa ttataggttc gttcttttac
    25441 ctcattacca attgttccat cctcattttg cttccgtact tctcggcgta atgcggaaaa
    25501 acgcaacttc ccaaatgtta aacctgaatc tacgacaata ccttctgtta atctcatctt
    25561 cttttcctcc tatgctttca ctaaatcatc aacatacaac acgtaatcag taaacccacg
    25621 attctcaatc tcatagcctt tggcaaccaa atggggattc acggctttta gcggttggtc
    25681 ttgatcaaaa tccttttcac cggcttccgc agctactacc acctcaatat catcggcccg
    25741 ttgcttactg gaatacaaat gataactgcg accaatcacc gtagtattcc gtccatatcc
    25801 ttctgttata atttctcctt caccggcata acttaacttt ccaaaggttt cagccatatc
    25861 tggcacgaca aatttcaatt ccatcttctt ttcctctttt cattgttagt tttggataca
    25921 aaaatagcgc gactactttt ttaggaggcg gtcgcgcacg ttggttctta ggatttactt
    25981 gtatcatctc atcaccttag ttccggcgat tccagaaata atagcccgcc gtcgcaaaaa
    26041 tcaaagtaaa accaatgaac agtaaaacat tggaattttt ctccccggtt tgagggaagg
    26101 tcttcactgt gggactagat tcttgagagc cacttggaac agttggtgtt tccggttgtt
    26161 tcggcgtact tagtatggtt ggaacttctt ttggtgttaa ggtttgagat ttttctttca
    26221 aatcttcatt gtgttttcca ttgatattcc catctttatc gtaattgatt tccgcaaaag
    26281 taaacttggt tccttctgga tattttccgg tatctacttt tttcgcaagc acagttttgg
    26341 tgaattcttt atcatttact tcataatcaa tcttgccaga tttccaaatt tctttgtttg
    26401 taccatccgg taataaagca tacagaattg tttcgaaagc ttcttttgag ccatccagta
    26461 catcatgagt aatcgacaca tcatcaaaca tatccaccac atcaccatga gtaaaggtct
    26521 gagaaccgtt ttctaggtgg gcctttgttt ggatagaaac atggtgttcc actgtacaac
    26581 tgacagtttg ggcttggtta ttcaagctaa catccttcgc tactggctta tcgcctgctt
    26641 caaaagcttc cttattttca tacacatagt tgaataagac aatagtttta tttaaaactt
    26701 gttcggcggt taatttatgc tgaattttcc aagttcctgt tttctctttg ttcgccaacg
    26761 ttgcgcttgt ttctgcaatc accactggtt tggctttttc atctttttct tgggcagctt
    26821 ttgtcgcatc cacatcaatg gcttgcgcta ccacatacca gtcttctttg atttcatgta
    26881 gattgtaact caatttatca actagctcgg tagaatccag agaagttaat tctttgtttc
    26941 cgtctttcca agtcgcaaga gaagttaaac tatcttcttc ctcaggcaaa tcatagagca
    27001 ttaaacggtt caaactaaca gaaaatgctt tgttcgtcag cttctcgtaa ggaacggtca
    27061 ccgttttaat tggttgtttt tggtcttgtt cggtaatggt aaagacatac tcactcttca
    27121 caaagtcttc tttgttttcc ttaaaagtag aacggatttc taatggcgta atcttttgaa
    27181 aaccttctgg ggcttctact tcttcaagta aataatcccc ataaggaaga ttttcaaact
    27241 tgccataacc atcaaaccct aattgctcgt tataagctgt ggtcgcttca tcttcggcac
    27301 ctgtgatttc attggtccct tccaatggcg acactttaaa ggtcagatca ttgaagccag
    27361 tttcggtagt gcccgcagct gatccagcaa atttaaagaa atcaaagcca aagcgaatca
    27421 cttgttcttt tgccgtaaca tttcgggtaa tcacggcatt tttttcgcta tcatccacct
    27481 ttttgatgga tacaggatac tttgtttcat caaggctata tccttcgggc gcttttgttt
    27541 cttgccaata atactcgttg atagctaaat gtttaacggc aacttggttc ttttcgtcta
    27601 aagtcaaagt gaccgtttca tcagaagctt tcgttccctt cgctaactct ggtttaaaag
    27661 cctcactcca tttaacagct tttccatcct tagcagtaaa caaggtgtat tcagcaccct
    27721 caaagactgc cttaccttgt gctttatccc cagtatcttt gtcttctttc gtcaaagtgg
    27781 tttcgccagt gacttcttga ttttgccctt ttacgttact ggtaacaagg gctacggttt
    27841 gattggcata cttcaattcg acttttacag gtttgaacgt attcacgaac ccatgactag
    27901 ctttagtttc ggtcacataa taggttccca attccaacgc attagcaatc tcttttggtg
    27961 tttccgcatg accgttttca tccgtggtca tttcttgaac gatttcaccg gttggactgt
    28021 ctttgcgaat ggcaaacgta ttaccagcta aggaataatt gtcattccaa agatcactcc
    28081 ctgtttcaac tccgctttta tccagaatga tttgcccttt ttcccgtgcg ttttttgaag
    28141 tcacgtaaat ggtttcgcct gctttaatgg tggtagtcat gggggtggta tcaatcgtat
    28201 aaggcgccgg tactgatttt tcggtaatgg ttacttttgt accatgagga atctcatcca
    28261 atgtagcaat gccttctttg tcagtagtca cgtcttttgc aggtaaagtt tttccaaagt
    28321 ctaaatggaa aaccgttcct ggtacaacat cacccgattc tttatcgact tttttgatct
    28381 ttaaagaacc ctccgtttcc acatcaattt tgattgtgta ggtattaggt ttatcaatcg
    28441 ccccggccat taaagtctgt tggccagcct ttttataggc gacaggtgtt ccggtaccag
    28501 cagatttctt aagcgtcagc acaccacttt cttttgaatt ggcatttggg gtgattatca
    28561 actgattacc attcacacga taatcaatgt ttgcggcatt ttccacaacc tcatcgaact
    28621 ctgacaaatt cagattattc gtatccgtca cagtagtcga ttgccctaat actgttttag
    28681 ccgtactatt atggaaggtt ggtttcttct gataatcgtc aatggcttga tttatttttg
    28741 cctcaatggc tgcgatattt acggcactac catctgatcg ttttattgag tgaagggtat
    28801 acccattaac ttcttgccag atcatcttct gtgccacaat atgagtatct gcatctgtac
    28861 ctactttttt ccataaaacg gaaactaatt tggctttatc ggacatatct ggtaacgggt
    28921 ttttctcata gccaggagtg aactcattgt aaatcgggac tcctggttca atacagaaaa
    28981 tatcttgttt aaagccgttg tacactgcat aatgcggaac agtgacttct gacattggac
    29041 gaccatcact aaaagttcct tcaacagcat attgatgtgc taaatctagt tctacggtta
    29101 ccgtttgtgg atgggtaatt tcatcagcaa aagtaatcgt aggagcaatt gctccaacaa
    29161 ttgcttgaac agccaaactc aaaatagtta atacacataa tttctttttt tgttttttat
    29221 acatgaaatg ttctcctttc aaattaagca caaaaaaata agatgctcgc ttgaacatct
    29281 ttgtttataa agtcttttta aaatttttat tgactgaata gaatggattt gagaatgaat
    29341 gagcctaaaa atttaatcta aaatacgaaa tatactgcct ttaaattaga acacatttta
    29401 gaacacaaac atttcaaatt taatcaaata taataaaata tatttacggg aaaaccttta
    29461 taaatcaagg tttttcaaac ttattcaatg atacgaagaa aaaaccaggt cttaagaaag
    29521 ctcgtaaagc atctcaattc tcaaaacgtt aatatccttt atatatcaac gttcaagacg
    29581 ctttccaatt atttggaaag tgtctt
//
LOCUS       DAYNVV010000030        29572 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.030, whole genome shotgun sequence.
ACCESSION   DAYNVV010000030 DAYNVV010000000
VERSION     DAYNVV010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29572
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.030"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(47..1342)
                     /gene="purB"
                     /locus_tag="ACGXWR_001536"
     CDS             complement(47..1342)
                     /gene="purB"
                     /locus_tag="ACGXWR_001536"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HFK0803111.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1355..2479)
                     /gene="purK"
                     /locus_tag="ACGXWR_001537"
     CDS             complement(1355..2479)
                     /gene="purK"
                     /locus_tag="ACGXWR_001537"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HFK0803112.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2472..2960)
                     /gene="purE"
                     /locus_tag="ACGXWR_001538"
     CDS             complement(2472..2960)
                     /gene="purE"
                     /locus_tag="ACGXWR_001538"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HFK0803113.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3376..4683)
                     /locus_tag="ACGXWR_001539"
     CDS             complement(3376..4683)
                     /locus_tag="ACGXWR_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HFK0803114.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4686..5267)
                     /locus_tag="ACGXWR_001540"
     CDS             complement(4686..5267)
                     /locus_tag="ACGXWR_001540"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HFK0803115.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5383..5480)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5839..7131)
                     /locus_tag="ACGXWR_001541"
     CDS             complement(5839..7131)
                     /locus_tag="ACGXWR_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFK0803116.1"
                     /translation="MKKKYVQVGLGGRARFFYETIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7128..7751)
                     /locus_tag="ACGXWR_001542"
     CDS             complement(7128..7751)
                     /locus_tag="ACGXWR_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803117.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7754..8590)
                     /locus_tag="ACGXWR_001543"
     CDS             complement(7754..8590)
                     /locus_tag="ACGXWR_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0803118.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8607..9494)
                     /locus_tag="ACGXWR_001544"
     CDS             complement(8607..9494)
                     /locus_tag="ACGXWR_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0803119.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9510..10793)
                     /locus_tag="ACGXWR_001545"
     CDS             complement(9510..10793)
                     /locus_tag="ACGXWR_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFK0803120.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDCLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11476..12159)
                     /locus_tag="ACGXWR_001546"
     CDS             complement(11476..12159)
                     /locus_tag="ACGXWR_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFK0803121.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12177..12794)
                     /locus_tag="ACGXWR_001547"
     CDS             complement(12177..12794)
                     /locus_tag="ACGXWR_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFK0803122.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12804..13628)
                     /locus_tag="ACGXWR_001548"
     CDS             complement(12804..13628)
                     /locus_tag="ACGXWR_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFK0803123.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13621..14181)
                     /locus_tag="ACGXWR_001549"
     CDS             complement(13621..14181)
                     /locus_tag="ACGXWR_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803124.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14355..15311
                     /locus_tag="ACGXWR_001550"
     CDS             14355..15311
                     /locus_tag="ACGXWR_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFK0803125.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15616..16572)
                     /locus_tag="ACGXWR_001551"
     CDS             complement(15616..16572)
                     /locus_tag="ACGXWR_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFK0803126.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16676..17278
                     /locus_tag="ACGXWR_001552"
     CDS             16676..17278
                     /locus_tag="ACGXWR_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFK0803127.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17366..18865)
                     /locus_tag="ACGXWR_001553"
     CDS             complement(17366..18865)
                     /locus_tag="ACGXWR_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HFK0803128.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18881..19405)
                     /locus_tag="ACGXWR_001554"
     CDS             complement(18881..19405)
                     /locus_tag="ACGXWR_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HFK0803129.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19703..20452
                     /locus_tag="ACGXWR_001555"
     CDS             19703..20452
                     /locus_tag="ACGXWR_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFK0803130.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20443..21228
                     /locus_tag="ACGXWR_001556"
     CDS             20443..21228
                     /locus_tag="ACGXWR_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFK0803131.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21197..21913
                     /locus_tag="ACGXWR_001557"
     CDS             21197..21913
                     /locus_tag="ACGXWR_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFK0803132.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22015..23034)
                     /locus_tag="ACGXWR_001558"
     CDS             complement(22015..23034)
                     /locus_tag="ACGXWR_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HFK0803133.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(23053..24054)
                     /locus_tag="ACGXWR_001559"
     CDS             complement(23053..24054)
                     /locus_tag="ACGXWR_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HFK0803134.1"
                     /translation="MTSTVFIILLGFVCRKKGIFSESVGKILSKVVLTVALPALAFRA
                     FMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYKGDKQTTLRVLTIFGSTTFF
                     GTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGLKMEAKNIKAMFVNPIIIAT
                     FAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPWLFQPMDYLAGLSSPLAWLA
                     IGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILAVLTATNILPVNFEALATIV
                     IMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVLTPVWIVVLQMIHGIGLFS"
     gene            complement(24332..25480)
                     /gene="nagA"
                     /locus_tag="ACGXWR_001560"
     CDS             complement(24332..25480)
                     /gene="nagA"
                     /locus_tag="ACGXWR_001560"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFK0803135.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(25556..26392)
                     /locus_tag="ACGXWR_001561"
     CDS             complement(25556..26392)
                     /locus_tag="ACGXWR_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0803136.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(26576..27793)
                     /locus_tag="ACGXWR_001562"
     CDS             complement(26576..27793)
                     /locus_tag="ACGXWR_001562"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFK0803137.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(27942..28103)
                     /locus_tag="ACGXWR_001563"
     CDS             complement(27942..28103)
                     /locus_tag="ACGXWR_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803138.1"
                     /translation="MEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGIAMDWAA
                     NLWNDYHDN"
     gene            28176..28259
                     /locus_tag="ACGXWR_001564"
     tRNA            28176..28259
                     /locus_tag="ACGXWR_001564"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28210..28212,aa:Leu,seq:gag)
     gene            complement(28499..>29572)
                     /locus_tag="ACGXWR_001565"
     CDS             complement(28499..>29572)
                     /locus_tag="ACGXWR_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803139.1"
                     /translation="YVFEKINVKNLLLVCSIYCLIPLTVMGETGWRATTLNYQWPVAF
                     SLLTFYPFFQLLRGEEINRKIYWVSIPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGR
                     YNYKLSVFSIISLAELIFSLTTPGNALRAAHEINKWFPEYKNFNFLNKLDLGISSFGK
                     PFFLDMNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNTMGQSFTYVN
                     GNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGIYLSFDNKKT
                     SIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKELMKSMSVQK
                     NEFMQFGLTVLGICTFIITVINR"
BASE COUNT         8844 a         6304 c         5063 g         9361 t
ORIGIN      
        1 tatttttgct attctatttt aattgaattt tgcaactcac tcttctttat tccaaaccta
       61 ctcgtttgaa tatcacgtca acgtttttca aatgatgatg ataatcaaag gcatcgtcta
      121 tttcttcttt agataatacc gatgtgatgg ttggatcttc ttctaacagc gggcggaact
      181 gcacttggtt gtcccaagcg tacgcagttt ttggctgaac aagatcataa gcttcttctc
      241 ttgtcattcc cttatcgatc aatttcagca taacgcgctg gctataaatc aaaccaaatg
      301 ttgcagacat attccgcttc atgttttcag gaaagaccgt tagattttta acgatattgc
      361 caaaacgatt taacatgtaa ttcaataaaa tcgtggtatc aggcaagatg attcgttctg
      421 ctgaagaatg agaaatatct ctttcatgcc ataatgtgac attttcatag gcagtgacca
      481 tgtgtccgcg caccactctg gctagaccag ccatattttc tgaaccgatc ggattccttt
      541 tgtgcggcat agcagaagaa cctttttgac ctttcgcaaa aaattcttct acttcacgtg
      601 tttcggattt ttgcaatccg cgtatctctg ttgcaaaacg ttcaatactt gtagcaataa
      661 gcgccatcgc tgagaaatat tcagcatgta gatcccgagg gagaacttga gtagagattt
      721 cttgtggacg gatccccaat tgtttacata catactcttc aataaatggc gggatatttg
      781 cgaacgttcc cactgctcct gagatttttc ctgcttctac tccttttgcc gcatgttcaa
      841 atcgttcgat gttccgtttc atttctgaat accatgtggc aagtttcaat ccaaaagtag
      901 ttggttcagc atggacaccg tgtgtccgac ccatcatcac tgtatatttg tgttcttttg
      961 ctttttcgcc aatgatttcc gtaaaacgtt tcaagtcttc ccgtaaaata tcatttgctt
     1021 gcttgatgag atagccataa gcagtatcta cgacatccgt acttgttaga ccataatgga
     1081 cccattttct ttcttctccc aatgtttcag aaaccgctcg tgtaaacgca acgacatcat
     1141 ggcgtgttaa tttttcgatt tccaagatcc gatcgatatc aaatgatgca tgctcacgaa
     1201 tttttttcac atcttcttgc gggatttcac caagttctgc ccaagcttca tctgctaaaa
     1261 tctcgacttc gagccacgca cggtatttgt tctcttccgt ccagatattc cccatttcag
     1321 ggcgtgtata acgttctaac atgttttttc tcctctaatc ccaaatattc gtttgtttga
     1381 tttcttccag cgtttgctgg atgtcttctg tcaagatagt gatatgtccc atcttgcgac
     1441 ctttttttgc ttgttttttt ccatagaaat ggaattgcca gtctggctta ttctcaatca
     1501 agcgatagct ttccagcagt tgttctccca aaacattgac cattactgca ttgcttatca
     1561 aacgtacttt ttctcctaat ggccaaccac aaatacctcg aatatgggca tcgaactgac
     1621 tcatagaaca agcttcaata gaataatgtc cagaattgtg aggacgagga gctaattcat
     1681 tcacatatag cccgcctgtt tttgttaaaa acatttctac ccctaaaaca cctgaaaggc
     1741 tcactgcttc tgcaatcaca cgggcaatac gctcagcctc ctcgatcaca tcctgatcaa
     1801 tcgcggctgg agcaatcgtt tcatgaagaa tattgttgtg gtggatgttt tccacgaccg
     1861 gaaaagtcgt gaaatctcct tgaccatttc ctgccaccat gatcgaaatc tctttttcaa
     1921 acgggatcca tgcttctaaa acacaggttc cttctcttaa aaggtccatg gcaggagcta
     1981 gatccgcccg acttttcaaa acatactgcc ccttgccatc atagccgcct cgagtggttt
     2041 tcaaaacaca aggatagccg atcccgtcaa tcgcatcttg gatatccgtc ggactgacga
     2101 tcgttgcata aggagcaatc acgatgttat tcgtttccaa aaaagatttt tctaacaggc
     2161 ggtcttgcgt aatcgcaagc aagtctgtcc cttgaggaat aaatgacatg ggtaaaatcg
     2221 catttaacgc ctctacactg acgttttcga attcataggt aatgacatct gttcttctgg
     2281 caagctcttt cagcgcaaag gtgtcatcat agacactttc aatgtgccaa tctgcaactt
     2341 gtgcggctgg acaatcgctc acaggatcca gcacacctac tttaaagccc atttcttttg
     2401 cactaatcgc catcatacga cctaattgac cgccaccgac gatcccgatc gttgaaccag
     2461 gcaacaaagg tttaaccaag ttgatcacta ctttctataa cagttttagc caacattgaa
     2521 cgtctttcag ccaatttagc ctccaattct aaatcataca tggaaagcat ctgtatcgca
     2581 agtagtccag cattaattgc tcccgctttt ccgattgctg tagtagctac aggtactcct
     2641 ccaggcattt ggacaatcga aagaagcgaa tccaaaccat ttaatgttcg tgattggacc
     2701 ggtacaccga taaccggcaa agttgttttt gatgcgacca tacccggcag atgcgcggct
     2761 ccccctgctc ctgcaataat gattttgatt cctttttttc gagcgttttg tgcatattca
     2821 aacatcaaat ctggggttcg atgagcagaa acgacctttt tttcataaga cacaccgaat
     2881 tcatccaata tttgacatgc ttctttcatt gtttcccaat ctgaagtact ccccataatc
     2941 acagagattt ttgctgtcat tgtttttcct cccagttttt ctacattcat attttaacaa
     3001 tcactttttt tgatgtcaaa gaaatttcga atgttaacaa agaaaaacat tttattgttc
     3061 gtgtttatta aagataaaaa aaaggaatgt gacaaaagtt aggtcacatt cctttttatg
     3121 gataaacggt gttctcctgc caactcctcg gtcacaagga acaatattca acaaacatga
     3181 gaagcttttt tttgaaattg ttccttgtga ctcggagatg aacggcaggc tcacgacctc
     3241 ttccttcaac ggtgttcaat cagctgaccc tcggtattag ctcaaacaaa cggcaaaata
     3301 cgaggaacta tttttccgtt tgtttctcta acaatcaggt caaaacgctg atttcacaac
     3361 ctttcttttg ctctattact tcttgaaggc ttcttccaat atttcttcat cttttttcaa
     3421 tccattaaag atcaaattca atatgatagc cgtaatgcta ctcattacga tgccatttcc
     3481 agtgaacatt tgcaatgttt gcggcatttg actgaataat gtcggcgtaa cattgaaacc
     3541 cagcccaaat ccaacagaaa cagcaacaat caatagattt ttatcattgc tgaaatcaac
     3601 ttccaacagc atacggattc cttggactgc caccatcccg aacatgacta acattcctcc
     3661 accaagtacc ggctcaggga tgatttgtgc taacgcaccg attttaggga ataatcctaa
     3721 aacaatcaag aagaatgcag agaaatagat gggttttctt gttttgattc ccgaaagttg
     3781 aaccaatccg acattttgag aaaagccagt ataagggaat gtattgaaaa taccgcctaa
     3841 gataacggca agtccttctg cacgatatcc ctttttcaat tcttcttctc caacattttt
     3901 cccagtaatg tcaccaagtg caaaatatac acctgttgat tctaccatgc tgaccatgga
     3961 aatgatgatc attagtaaaa tcgaccatac gtcgaaagtt ggtttaccaa aataaaaggg
     4021 ttgtggaaca tggaacaacg gcgcatctcc aatcgcgctc agatcaatca ttcccatgaa
     4081 agcagctaag atgcttcctc cgactaaacc aatcaatacc gcgattgaac gaatgaaccc
     4141 ttttgccagc atttgcacgc ctacaattag gagaatcgtc acaaatgcaa gtagcagatt
     4201 tgttttgtca ccaaaatcag ctgctgttgc attacctcca cccattttct cgattgctac
     4261 aggaatcaaa gtcaaaccaa taacggtgat aaccgttcct gttactatag gagggaatag
     4321 ttttttaatt ttagaaaaga caccagaaac taacacaaca aagatcccag aagcgataat
     4381 agatccgtag atagctccta ctccttcatt ggttccgatc aagatcagtg gagctactgc
     4441 ttggatcgca catcctaaaa cgacaggcaa gccaattccg aaaaatcggt taactgtcaa
     4501 ttgcaataat gtcgctaatc cacacataaa gatatcaatt gaaatcaaat aagtcatctg
     4561 ttcttgatta aagcctagtc ctgtaccgat caaaagaggc accgctactg ctcctgcata
     4621 catcgctagc agatgctgca gccctaaaac cgcagctttt ccattttgtg tttctttttc
     4681 cacgattatg cgtcctcctc aagaaactca acttgtccat tcgtcaagga agcaatacgc
     4741 gcaagagaaa cgactctcaa tcccatttct tcaagtaact gacgtccatc ttggaaagac
     4801 ttttcgatga cgatcccgat tccttctact tgcgctccag cttgctggca taattcgatc
     4861 aatccttttg ccgcttgtcc gtttgccaag aaatcgtcga taatcaatac tttgtcttct
     4921 gaagataaaa atttacgaga aatagaaatc gtacttgtca cttgtttcgt aaaagaataa
     4981 acagaagctg tcaataattc ttcatccatc gtcaaacttt ttgcttttct agcgaagatc
     5041 attggaacat ctaattctct tgcagcaaat aaagctggtg cgatcccaga agcttcaatg
     5101 gtcacaactt tcgtgattcc ttgttcttta aatacttctg caaaccgttt tcccatttgt
     5161 tccatcaata cagggtctac ttggtgagtg acgaagctgt cgacttttaa tacgccctcg
     5221 cctaatatac gtccgtcttt ttgaatacgt tcaactaatt ctttcacttt atttgctcct
     5281 ttatcattta ttaataccga aataaccgct tttgtgcaaa aacctactat gtttctgtta
     5341 aagaaaaaca ccctccactt tatcataaga aaagaagggt gaaatagcca atcttttact
     5401 tatagtccag catttacggt actggctaga aactgtcatc catattatga cgatatataa
     5461 gtaggtatgt aaaactaata atagtgtaaa ttcattttct tgcaactgtt ttgcacgtga
     5521 aggcagtttg ccatatttga ataaaaaatg ttgtttcaaa tattgaaaac agtctaacac
     5581 tactttctga aactgacaac gtggtttact tatttttttg taaaatctaa tgatttttaa
     5641 tgcattattc ctttttgttc gggtttaaat agttattttt attttctcct atctaaaaaa
     5701 gcagcccaca taaaaagaag gcatgacaaa aagcatgtca tagccccttt ttccgaataa
     5761 atagtgttca aaagacagcc tatcggcaat aaggcaagat tttataaact acgggaagta
     5821 atttccgtaa atctattctt attcttttaa gctgacaagc tcgtcaatca ctactgcttt
     5881 tcctgaagca atagaatgat ttgctgcgat tcctgtcaaa atcgacaaaa taccatctac
     5941 gtgagttgct gcccgattcc acggatcttc ttctttttct tcaccaaata gatcatctaa
     6001 taaacgcgga tctcctccgc catgtccgcc cgcttcttgt tcgacgatta cctcatatgg
     6061 ctcaccgaac atcggataga catggatgga ctgaagaacg gctgctcctt catccttttt
     6121 atctccacct gcattgatgt aagacttttc gatcactttc atttcgatcc gtcctttgct
     6181 gccattgaaa gaaacattga atccttccca cggcatatac gcgtttagcg aatacgtcaa
     6241 aatcgcacca gtttcatatt tgaccgttac gcctagtgta tcttcaatag agatatcatc
     6301 ggaaaataca ctgcggtcac gaatatatcc actgtctttt tctgcttcta aatacatttc
     6361 tcgcaattcc tcattggctg acaggtctat agcaaatgga tcagctttag ctagttcgct
     6421 tccatagcat cgactgtaaa atatttctac tccgcgtttc tccgcattat gcatcccata
     6481 aaagtttaat ccaccgaatg caaatacctt ttggggacgg ctgttcaacc aaaaattcac
     6541 tagatcaaaa tgatgggtag atttatgaac aagaagcccg ccgctattgt gcttatttcg
     6601 atgccatctt ctgaaataat ctgccccgtg ttgcgtattt aacagccatt cgaagtggat
     6661 agaaaacaca tcaccaatca catcactttc tatcagttcc tttatcttcg tgtgatacgg
     6721 tgcataacga taattaaaag tgactcgcag gcttcttccc gtctgttttt ggaccgttat
     6781 tatttcttga gctttttcct catcgatagt cagaggtttt tcgcaaataa catcatatcc
     6841 ttttttcatt gcacgaatga tataatcatg atgcgttcga tctactgacg taataatgac
     6901 ttcagccggc cgtacgtcat ccagtagttg ctcaaattgt gatggcatac atgtctttac
     6961 ttttttctgt ccatacttgt tcacaagtat ccgatttgca taatccatcc ttgtttgaga
     7021 tacatcacaa aaaccgacta gttcacaagt ttgatgatac gtagaggcaa ttgtctcata
     7081 aaaaaaacgc gctctcccac caagtccgac ttgtacatat tttttcttca tttaaagtca
     7141 ttctcctttt cttttaagca aaatactgtg acaaatggca gccctggata cagtaatgca
     7201 gtgagtaaaa aatcatgctg tatacaccag aacagtccat acaaaaggca taaataccac
     7261 agaaacccct tgacgttttt tgacaacagc cagatattcc ttttgatcaa ataaacaaga
     7321 ctatctgctt tatcttcttt gcagatatca attagcgtac taaaaaaact atgggataca
     7381 aaaagcaaca gacacaatag aaaaggaatc agataccaag ctccaatctt tcccactaat
     7441 aaataccaat caactgcaaa aataatgaca aacagctgaa acaacgtaat gatgaaacac
     7501 atccgtttga tttttccttt cctccaacat accttttttt ctgccaagta atggacagat
     7561 agataataag aaggatacat catcaaaaaa taaatcagat agacaacacg agcagacagc
     7621 actaatccta aagtgaacaa acatcctaga actaaagcga aaagagcatt actgataaga
     7681 ctggttaaaa aaatccgaca gacatagtag ttgagcttgt aaagaaacat ctcttctatt
     7741 ggctttttca tattcagccc ttcagaccgc ttgtactgat cccctggaca agatatttat
     7801 tgaagaataa gaaaatcaga aaaaccggta gcagcgacaa cgtagacatc gcaaacatac
     7861 tcgcgtaagt cgtactagat ccagcgtctg caaataattt gatggcaatc gataccgtgt
     7921 aagatctcgg cttgtttaaa taaatcaatg gtcccatgaa gtcgtcccat ttccaataaa
     7981 actggatgat gatcgtcgtg atgatcgaag gtttcagcaa aggaaaaata attttggtaa
     8041 agacactata cttgctgcat ccgtcaataa tcgctgattc atctaactct ttggggatgc
     8101 tgaccatgaa ttgcatgatc tggtaaatga aaaatgcttg tccaaaaaaa tgtggtaaaa
     8161 tcagcggcac atacgtccca accaaattca gccgattgta aataataaac tgcggaatca
     8221 aaatcacttg tgcaggaatc atcatcgtta ctaacatgac gacgaaccag aatctttttc
     8281 ctttgaaatc gattctcgat aatgcgtaag caatacaagt cgagctcaga actgtcccta
     8341 tcgtcgaaac tgcagagatg acaaacgaat tcctaaagaa agtaaaaaat gaaattccag
     8401 caaaccccgc ccatcctttt gcgtaatttt cccattgaaa agtctctgga atcaaattca
     8461 gcgaaccact cataatctct tgatccgttt taaaagaacc tgcgatcatc cataagaccg
     8521 gataaatcat gactagacct aatagcaaaa taaaaccgta ttgaaaccat ttcgttactg
     8581 tattattcat ttcttcctcc tctcattcac acaacgaccc atttttttga tgatttgaaa
     8641 atcagaaagg tgacagctcc cataatcaac agcatgatcc acgaaatagc actagcatac
     8701 cccatagaat taaaagaaaa agcttggtta tacacataaa gagcataaaa gttcgtggca
     8761 tcattcggac caccttgggt aatgataaat gcctgcgtaa aagtcataaa cgccgcgatt
     8821 gtctgcataa ccaagttata caaaatgatc ggcgaaagaa gaggtaacgt gatcttgtaa
     8881 aacgtctgcc atttgttcgc tccatcgatc tctgccgctt cataatacga gcctgggatc
     8941 tctttgatac ctgcagcaaa gatgatcatt gccgaaccga attgccaagc agacatcaaa
     9001 acaagaggga tcatgaccag tttttgatcg ctaaaccagg aaagcgcagg tgcgcctaat
     9061 cgttccagga aaatattcac taacccgttt ttagaaaaca actcccgcca aactagagcg
     9121 atagaaatac tgccaccgat caaactaggc acataataca aagaacgaaa gaaagtcgtt
     9181 cctttgatat tcctcgttaa aagataagca atcaatagac caaagatcag tttcacaggt
     9241 acagatgcaa atacatagag aaaagtgact cggatggagt tcaaaaaacg ggcatcactc
     9301 agcatcttta tataattatc caagccgatc catgagactg gatttcccaa acgataatcg
     9361 gtgaacgaat aataaagtga caagatcatc ggtatcactg ttatcaatag aaatcctagg
     9421 atgaatggag aagcaaatac gtaaccgacc acattgtctt gatccaagaa ccgttttagt
     9481 ttttcttttt tcatgccttc ctcctgctgc tatcctagaa tgtttgacgc aaactcataa
     9541 agactctctg ctgcttcttc tgctgttact tcttcataaa tgactttttc aactaaaaga
     9601 ttgtattggt cttgaatttc cggattcaaa gcactatcaa agacattcac ttcgccgttg
     9661 tccatatcgg aaatcatttc taaacaatca aatgtcgctt gcaaagttgc atcatctgca
     9721 cgagcgagct gttctcgaat attcgacatg attggtacac cacgttctcc ttttaaaatt
     9781 tcattggctt cttcactgtt ttgaaagaaa tcaataaact tagcagcttc ttctttatgg
     9841 gctgagcttt ttgccatact cagcatttgc gaagaacgta aagggatacc agattctcca
     9901 tctgcttttc tgcgaggtgg attaatcaac tgaatctcca tatcttcagg agcccctgac
     9961 aatatttctg tcaactggtt acttgataga aacaccattg ccgcttctct atccctaacc
    10021 gcctgaaaag acagatccgt cgtacttgca gctccaccac ctggttctgg atgggcccct
    10081 ttgtctacca gatttttacg cagctggaaa aaatctgtta gatagtctgg attttcaaat
    10141 cccaagctgt tagatagatc ttcccgatta taaaaattca atcctttctc aacttgtggt
    10201 atttgaataa tacagccagc tataaaatct tcgaatcttg aaatagcata gattcctaat
    10261 tcttcagtga tttgatagct gatttgttca aattcatccc atgtccaatt tgaagctggt
    10321 tcagggatat ttaattgttc aaatatattt ttattgtaag caatcgcaaa cgaattcacc
    10381 ccgttagaca gtccaactaa ttgcccgtcg taagtcgtcg ttgctaaata ggattcatct
    10441 gcattagaaa tatcaattat cccttgctcc acatattcat ctaatggttc aatctgattg
    10501 atgtattgag gaaattgatt gttcagttgg aaaatgtccc agatatcatc tgatgctgct
    10561 agtgtaccta attttgtgta atatccttca taatcataaa attcataatc gatcgtcaca
    10621 tggggatttt tttcttcata aagctcgatt acttttactg ttgcatcgtg tcggacttgc
    10681 gaaccccacc aagccatgtt cagcgtgatt tttttgtcat cttcttgccc acaagccgtc
    10741 aagaagaata acataacact taaagctaag atgattctca ttcttttctt cattctctgc
    10801 acctctactt ccattgttat ttttcaatat actgtatttt tatacagaac atatttatta
    10861 aacgatcttt ttcaagggga ataaaaacca agacttgcct tatcgttctg cctaggatga
    10921 acaactcaat actttcaaga aaaattagat agtgctgatt cttctttcat cgctaaaaac
    10981 acttcttgct tcaatgatgg gaggataatt acgcaaagaa aaaaggatat cagacaactg
    11041 cccaatatcc ttgacatagc taaataagca tgcttcttcg tgtgcgctct tccctaaaaa
    11101 acagaaaaat aactagtaat tctgtatgaa attaggtaca atatacacgt cgatgcacaa
    11161 gcattgacta tggcaacttg attggtcagt tcccgctgac ttttcaagcc ccgacaattt
    11221 agctgctact aaattgtcgg gtgccttttt tagtttttat tcgtttttca ttctatagaa
    11281 agcgcttcaa taaatcaaga catttttttg ttagaatgct aataataaca aaaggtttta
    11341 actcttctta tgtacattac aggtaaaaaa acaaaaaaat ttctcttttt tttgaattct
    11401 gaacaaatag tactggagta caaaagacga ggaagagcca ctatctgctc ttcctcgtct
    11461 tttgattctc acctgttatt catgattctt tttctcagtt tcccgatatt tttccatttt
    11521 acgactaaaa agctctccgc tacttggtgg cgtatatgtg atggcatttg ctcctgcttg
    11581 aatggtctca gcaatacttt cttccgttgg accacctgtc gcaatgatag gaagttcagg
    11641 atatttttta cgaaaatggc gtactgcttc tgcagtttct ttacctgcac tgatattgat
    11701 aatcgaaata ccagctgcta acttttcatc tatttctgta tatttcgacg ttaccgtact
    11761 gataactgga atatcaacta ctcgacaaac ttcttttact gtctctaaag gcgtaggacc
    11821 gttcaaaacg acccctaacg aaccttgcgc ttctgcgaac atgctcatgt aggaagaacg
    11881 agcaccttgt gtcaaaccac cacctacacc ggagaaaact ggaatgtcag ctgcctcaat
    11941 aatgctttta gtaatcgctg gatgaggtgt aaaaggatac acagcaatta ctgcattcgc
    12001 atttgtatta cgtatgatcg caatatccgt agtaaagatg atcgaacgga tcaattttcc
    12061 aaatatcttg atcccgcttg cttctaaaat gatttccggt actcttacga tatcttttct
    12121 caattccgtc atgatttctg gcgtaaattg ttctgccatc agccacttct cctttgctat
    12181 ctccggtcat actgattcaa ttgatacgtc tcgatgacct ggatgatttt ttgcgcataa
    12241 ccggggtctg tcgcataacc tgcatcttgc aatgcttgtg cggcttcctg atagttggtg
    12301 gccgtaatca ctttttcata cagcgcagga ttccaatcta ctccttggac gaacagttgt
    12361 gtatggtcat ccatggactg ttcccatgaa tcatacactt tgaagtctcc ttggatagtt
    12421 atccattctt cgttaacaaa ttcctttgtt tccaggctta ctttcttctg atccccataa
    12481 gccttgatcc cgaaaagatt attgtatttg ctagccaagg tactttttcc ccaatttgat
    12541 tctaatatag cttgtcctaa aatgatacta ggaagcactc cataaccatc ttgtagttct
    12601 tgggcatgcg gaacaagccg ttcaataaat tgctgatggg attgcgcttc attttcttgc
    12661 tgattatcag taaaaggaga agacagattc ttcaaggaaa aaacaaaggc taagagtatc
    12721 actgctacac cggcaaccac tgctggccaa cggatattct tgcgcttttg ctttttccac
    12781 ttttttttcg ccatgatcaa ttcctacttt tcatttaatt cattcagata ttcttctagc
    12841 gtcaattggt gtttggtgat atactcagcg ttttctttac cgacataacg taagtgccaa
    12901 ggttcatatg tgatcttagt tatatcttcg tgtccttttg gataacgaac gataaatcca
    12961 tactgcgcag cattatctgc gatccattta gctccaggct gatctccgta acttgcatcc
    13021 aatacagtag aaggataact gttgtaccag ttttgatcga cgacatcgac tgccagacct
    13081 gtgtggtgtt cgctgtatcc tggctccgta atcgtttctt tagtaatctt tgtcgcctcc
    13141 tcttctgata caccttgacg actcatcaca tcttggacat tttgttcgaa aacttgttgt
    13201 tgggatgata cagaccggta agctgagacc atcactaatg gaaatccagc tgcttcagca
    13261 gccttggcaa atgcttcata ttctggagca atgcgtttgt cgatcaagta tccgttactt
    13321 aatgatgcca attgagtaga ctcatcaatt tctttttcta atttgtgatc tggaccaacc
    13381 aaaactagct tccaatcgtc tgttttaaca tctggcaatt gtttggacgt acgatctttt
    13441 gtttctttgt cctttacctt gctgctggtt gtttgactgt tcttttcttt actagcagtt
    13501 gttttggtgc ttgttcgttc gactgcttga ttgccggctt gaacatgcga atcatcatcg
    13561 ctaaaaataa catagcccat tgctgcgatc ataatcacaa ctgctccaaa tcctaaaaat
    13621 ttattcactt gaaaaatcct ttcgttgttc ttcacgttcc ccattcgcct catgaacgta
    13681 agtttcttcc agattttcat tcacccaatc gagaagttcg attttttctc cttcgatctg
    13741 tttttgaaca tctgctggca gacgaaaatt caaaatatca tcatagcccc attcatcata
    13801 ttgaatactt actttcaagt caaggtatct accagcctgc tgattatttt tcaaagggat
    13861 cagctcgact tttgctgctt tgctgctaag ccatttttgc gcgatgcgtg ttttgatttg
    13921 cttgtactct gcaacggcaa cgtttcgttt ttcgggaaaa ataatcgttt gacgcaaaat
    13981 cttttgcgtt agcatccatt cataatcagt gaaaagattt tttactttct gcatcgcttc
    14041 agatggcaga tttttctcgc catctttcca tttttgccat tgttctggac tgatcagcaa
    14101 gtattcatct aaaaaatttt tttcagtttc aaactgttct aataatacac tcataataag
    14161 atcaatatat acttgatgca cgtttatccc ctccttttaa ctattctact taagttttga
    14221 tcaaaaagca cctcttaaat cgctgctttc atttttttta atgtttcaag tcctctcctc
    14281 tttattcttc gtgatttttg ttataataat agacagacaa gaaactcaat ccaactatga
    14341 aggagcgttt tcagatgaaa aaatatcaat ggggaatcgt tggtcttggt accatcgcac
    14401 atgagtttgc cgaaagcttc aatcaagaga cgagcgaact aacagcagtt gcttccagaa
    14461 cttcagaaaa agcggaaaac ttcgctcacc gttacaatat tccaaaagct tacggaagct
    14521 atcaagaaat gttagacgat gctgaaatcg acatcgtgta cattgctgta ccaaatagac
    14581 agcatatcga ccatatcttg gcagcattgg aagcaggcaa acacgttcta tgtgaaaaag
    14641 ccatcacgat gaataaaaaa gaactggctg acgctatgcg cttagcagaa gaaaagaatt
    14701 tgatcttagc agaagcgatg acaatcttca acatgccact ttatcagcag ttacgctcaa
    14761 taatggatac aggaaaactg ggggctttaa aaatgatcca agcacctttc ggcagttaca
    14821 aagaaccaga ccctaaaaac cggttcttca atccagaatt agctggagga gctctgttgg
    14881 atatcggtac gtatgctgta tctttcgctc gtttcttttt gagctctcaa cctgaagtag
    14941 ttgcctctac aatggttcct tttgaaacag gcgtggacga acaatccgtc actatcttgc
    15001 gtaacaaaga aaatgaactt gctgctgtca gcttgacttt tcaggcaaaa atgccaaaag
    15061 tcggtatcgt tgcctttgag aacggttatg tgacgattgc tgattacccg cgtgctgatc
    15121 gtgcggagat cttatttaca gatggtacaa aggaattcat cgaaagcggg aatacatctg
    15181 aagcaatgaa ttacgaaata aagaatatgg tacacatgat tgaaggtgac ttgcccaatc
    15241 gctctctctt cttgacaaaa gatgtcatcg aaatcttgga tcaaatgcaa gttctatgga
    15301 aaaatatgta attttaaaag gttgtgaaaa agctgttctg catcaagtaa taagaacagc
    15361 caaacaaaaa tagctcctcc tatttttcgt ttggctggac ttattaccgc agaggaaagc
    15421 ttttgaacac cgtttaagaa agaggttgtg agcctaccgt tcagctccga gtcacaagga
    15481 gcaatttcaa aaaacagctt ctcatgtttg ttgaatattg tgacttgtga ccgaggagtt
    15541 gacaggagaa caccgtttaa agaagaggtt gtgaaatcag ctttttgacc tgaatattag
    15601 ctgaattcac aacctctatt tttggatttt ttgttgggag aattctgcct tgatttcaat
    15661 aaaactttta aaagactgca aaaactggaa caattctgct cgatcctcga attcagggcg
    15721 actagtcggc agaggcattt gccgatacaa tacataaact tcttcaatac gtgttaaaat
    15781 ttgtctgcca tcatttgact ctgaaaatgt ttctgcagta taaatcaata aaccatagat
    15841 atgttttcca taataagctg gttgctggat tctctctaga ttttccagca tgtctttaat
    15901 cacattggcc tgtgctcttc tcatagagaa gtaagtttcg tagtatagcg gctgtctgag
    15961 ccagtagttt tcttgatgtt ctctggcatc ttcttggctt tcgcgaatga atgtcagtaa
    16021 atgttcgcat ttgatctgca catcttcttt attttctgat aaaagaaatt ctgccatttg
    16081 tctcaaaata tttcgaaatt ctttttcgat ctgtatttgg ttttccttca gctgcttcgt
    16141 acgatctggc atgtaaacat ttgcaagcaa agcaaatact aatccaatcg ccattaatcc
    16201 cgcttcattg ccgatcagct gccaagacat gttttcctcc actaaataat gagtgaccaa
    16261 aaccgaattt actactatcc cttcggttaa tttgaagcga gaggcaagcg ggatgaacag
    16321 gaataaaaaa agactgaagc caaaaatagt atacccaaca gcaaaaaaac tgaacagtgc
    16381 tgttgccgta gctaatataa aggctgcgat tcgattcatg cccgtacgca atgtagagcg
    16441 cttggtattt cctacactta ataatgcaat gatccctgca gctggccaat acaacagcga
    16501 taagctaccc gctgtgacca tcgaaaagaa gacactgatc actgttttga ctgttcgcat
    16561 tcctatacgc atttacttcc ccctttttta ttttaattat acttgaataa tgaaaaacta
    16621 gctatcagac aaaagtttag gtatgatagt aaaaagacca aaaaggagaa tctctatgca
    16681 atttggccgt tttcgactag gtatgcgtac gatcaaaagt gccttagctg tttttttatg
    16741 tatcttgttt tttcatttga ctcaacgagg aatcccgatg attgctgcat tatctgctgt
    16801 tttttctttg cgtcaggact tgactacaac cgtttctttt ggaaagtcta ggatcatcgg
    16861 caatacatta ggtggtacat tagctatcat ttattttttt gtcaaaagct attttcacaa
    16921 tgattttttg gtagaattga tcttgcttcc tattctagtt attattgtga tcgtcgtgtc
    16981 agatggtatt aacaataatt ccggtatcat ttccgcaata gctacgttgt tgctgattgc
    17041 gttgagcatc cctcaaggcg aatccgcttt gtatgctatc caacgtgtac tagatacttt
    17101 tatagggaca ttcattgcaa tcggtatcaa tttctttctt cgtcctcctg aaacagaaaa
    17161 gaaggaagaa ctatcagaag atttggtcga actccaaaag aaagaacgat tgctaagaac
    17221 aaatttacaa gagatagaag ctaagatcca aaaacaaaag aaaaatagcg aggactaatt
    17281 ttcttttgca ataaaataaa aaaatggaga gaagaacttt aaaaagtctt cctccatttt
    17341 tgattgaacg gtgaagtgta ctactttatt cttccttcat cgagttttgt tctgcctctt
    17401 ttggcgcttc atacatattt acttggctag tagtcccacg tgtcgacaaa ttctctacga
    17461 tttccttcaa gtcaagtcct gttgtcgctt ttagtgtttc ttgagtagaa gaaagcaaat
    17521 ttgtggcata atttgtcact cggttcgctc cactggtttc tcctgaactg cttcctgtat
    17581 cgacaacaga gattttttcg atatttccta gcggctgtgc tgcttcgcgc atcaattgcg
    17641 gtagcatatc gataaccata ctcaagacag ctgcttcgcc atattccttg aaggcattgg
    17701 cgatcttttg ttttgcttcg gcttctgctt ttccttttgc tagtgctgct tcggcttctg
    17761 cttgtccagc taaacgtgtc ttattggctt ccgcttctgc cagtgcttcc acacggaatc
    17821 gttctgcttc ggcttcagtc acttctttga ctttttgagc ttgtgcttct tgttctttag
    17881 cgtaccgatc ggcatctgct tttttcttca cttccgaatc atattgcttt tcacgacgtg
    17941 tgatttcttt ttcttccagt tcgatttgtt tttgacgttc tacgatttta atctgcattt
    18001 cctgttcgat tacttgttgt tgtgctcggg cactttctaa attgtaggct tggtctgctt
    18061 ttgctttagc aacatcttgt tcttgtttgt aggttgctaa tttcagttct ttttctttta
    18121 atgattctgc gatctctgtt tgtcgctgta attcagctgc ttgtgattct ttttctgctt
    18181 gagctttttt gatacgcgtt tcttttagag cttccgcttc tgctatatct gcatctcttt
    18241 tgacttgggc gattcttggt ttccctaaag agtcaagata accgtttttg tctctgacct
    18301 ctttgatagt gaaagaaacg atgatcaacc ccatttttgc aaggtctaca gaagcgactt
    18361 cttgtacgct ttgactgaac ttatcgcgat tttgatagat ttcttctaca gtcatagaac
    18421 caagaatcga gcgcaagtgt ccttctaata cttctcttgc ttcattttcc agttcttctc
    18481 ttgtcttgcc taaaaactgt tctgctgctg tagcaatctc ttctacagat gaaccgattt
    18541 tgatgatcga agtaccatca cacatcaccg gtacgccttg ttccgtatac acttcagggg
    18601 tggagacgtc caatttactc gataatagac tgatccgatt cgaacgttga aaaactggca
    18661 agacgaatgc gccacctcca cgcacaattt tgattttgtt attgctttca tcaatgtgca
    18721 catttttgct tcctaaataa cttccactga tgatcaacgc ttcatccggt tttgctgtct
    18781 ggtacttcgc tacaaagacg atcagcaaca tcagtaaaat caaagctgcg attgcgatcg
    18841 cgataaaaac aactggtatt tccatttaac acacgctcct ttaagctttt atcatgcttt
    18901 cataaggcat gacataacag attctttcct tgatctcaat gatcaatact ttcgttcccc
    18961 gctcagctgt ctgttcttgg gggctgtaaa aacaagctgg acgactaatg gaaccggtaa
    19021 cacttttcaa ctgaatttct cccatacctc gtacagggat cggtgtgatc acaacagcta
    19081 cttgtccttc cagagttttt tcagaagacg acatcgttga ttcggcatgt ttcatcggca
    19141 tcaatatata gaaattaagc aaaaatacca acactatcga tatgcctcca ctagcaataa
    19201 ataaaaataa agatgattga tctgttaaac gctcacctag aaaaccaaat aagcttgtga
    19261 aagttaacca agggataata agcatcggat caagcgggcc atcaaaatcg aatacatctc
    19321 caaaaataat caataggact gccaatcctg cacaaatcag caatgtatac caataaatcg
    19381 tctcaagtgc gattccccct atcatataca cgcctccttc catttctacg tctatcatac
    19441 caatgtttga aaattctgta tagcttcttt taccgactca gtggtgtttt ttataggaag
    19501 gttgtgttta tcgttgacaa tttgttaaat ttttgttttc atgttaaaat tttcacaata
    19561 aattctttcg aggtagccta tgtttccttt ttttaagaaa aaaccattaa agctccagaa
    19621 cacgatcatc cttgtcgttt gtttctccac attcgtttct ttgattgttt ctgccatatt
    19681 gatcaggaat tttattcttt cgatgaaccg atctagtgtg tcagataaaa tctctagcat
    19741 tgctaaaatc gttgccaatg ataaactcat ccaaaaaaag ctgcagactg gtgacccgac
    19801 acatgcgatt caaggaataa caaatgaaat catgattgca tcgaatttag attttatcgt
    19861 tgtcatggac cctgaaggca ttcgatattc tcacgcagac ccaagttaca tcggtcttcc
    19921 tttctcaagt catgaagatg tgaaaaaagt gattggagga caagaatttt tctctgaaaa
    19981 agaaggaatg ttagggttcg gcttccgcta tttcgtccct atttattatg atcaagagat
    20041 tattggtgca gtttgtgttg gcttaacaaa caacacgatt gacaatcaag tcaaagatgg
    20101 acaaaaaatg attgtttttt cattgattat tggacttagc gtaggcatca taggcgccgt
    20161 ttttcttgcc caaaaaatga aaaaagtact gcttggactt gaaccacaag aaatagcaga
    20221 acagttaagt gaaaaaacga ttatcgaaaa tgaagtagat gaaggaatct tagccatctc
    20281 ttctgataaa actatcctct tgatcaatac acctgcaaaa aacattttct accaaacaga
    20341 gcagctattg gatttcgaag taggaaaaaa atcagtgata atctatatga cgttttgttt
    20401 aaagagacga ttgagcatca aacgaccgtt cggactcaat ccatgtattt aaatgggata
    20461 gaaactattt ctagcgttac acctcttttt agcaatgacc gttttttagg agcagtcgca
    20521 actttacgaa atcgatcaga agtaatgaaa ttaatggagg agcttggggg gacgaaacaa
    20581 tatataaact ccatgagagc tcaaacccat gaattcatga ataaacttca tgtcatttct
    20641 ggtttgattg atttgaagaa gtatgaagaa gtcacccatt ttatccagca gctaaatcaa
    20701 aattataaaa aagagattgg ccaagtctca agtctgatca aagtacctgc aattgccggt
    20761 tttttattag gcaaaataaa cgaagccaaa gaacaatctg ttgaaatgct gttagaaagc
    20821 gattctttta tccctaaaat ggagatggat gactccatcc attcactttt gcaagtgtta
    20881 gggaacttac ttgataatgc aaaagaagcc gtgctacaaa aacatgaaag aaacggacag
    20941 gtccggattc atttaaacta tgacacagaa gctgaagtat tcatcgtgac cgtctgcgat
    21001 gacggtgtcg ggatatcaga agaaatctca gaaaaaatat ttacgctagg tttttcgacg
    21061 aagggaatca atcgtgggtt tggattgaat ctcatccatt caatcgtcaa acgccacggt
    21121 ggatttttag aattttccaa acaaacaaat ggcggtacaa tcgtctatct agaattacca
    21181 aaaaaggaag atcaaaatga tgacaaatgt cctgataatc gaagatgatc caatggttgc
    21241 agaattgaat cgtacttttg tggaaagcat ccctaatatg aacgtaatcg aaagtttcag
    21301 aaatgtagaa gaaggaaaaa aatatttcag acaaaaaaac gcagatctgc tgctgcttga
    21361 tgtatacatg cctggcgaaa gtggtatcca ttttttatct tggcttagac agcaaggaaa
    21421 tgatatccca gtgattttga tcactgctgc agatgatatc gaaaccataa agaatgtgat
    21481 ccgctacggt gccttagatt atttgatcaa accgttcact ttgcaacgtt ttcagctggc
    21541 gatcgaaaag tatcttgctt tctctcagac aatccaaacg actgaaaaag ccgatcagaa
    21601 attgatcgat caagtattca accacaccac tcccattcac gaaataccat cattcatcga
    21661 tttgcctaaa ggtctgtcaa aactgacttt aaaaaaaata agtgcattta ttctaaaaga
    21721 agatactatt ttttcaacaa aagaactggc tcaaaaaagc tcactgtcac gtatatccgt
    21781 caagaaatat ttgaattttt tagtagaaca agatatattg aacgaaagaa tcaaatattt
    21841 ggaaatcggc cggccgctaa cctgttatga attgacaaag aatgggcgga aaaagctcac
    21901 agattactgt tgagtcatcg aattatccca tacaaaatag tccaagtata cagaagtaac
    21961 aactgtttac ttggactatt tttaaacatt ttattgacga atatccatgt tttcttatct
    22021 taattgacgg gctttaggaa gagatacctc atttttcgtt tttccagttt ctattatttc
    22081 acgaaagttc tcgaaacttg tcgaaatcat atttgataat gcctcatctg tatttgaacc
    22141 tacatgcggg gttacaagaa ctctagggta catttctact aattgctgga tagcagggtc
    22201 tggaatcgtc tcccatggct tgaaggatcg gaaaaaaacc tctgtttcat ttgcaaaaac
    22261 atcggttgca aaaccagcta aatgattgct tttcaaagct cttaaaatag cttcattatc
    22321 ttgaagctct ccacgggctg tattaatcaa gatgctacct tttttcattt gagctaaaaa
    22381 tccttcattg atcatttgat cgttttcacc tgggatatga ggtacatgaa tactgacaat
    22441 atcgcttttg gctaataact cttcaagcga gtggaacgtc aatacttttt tagcagcttc
    22501 tgtctgatga atatcgtagc cgatcacttt ggctcctagt cccttaaaca aaacagcttc
    22561 cgtcaaccct atcctgcctg ttcctatgat ccctactgtg caatttctga tttcacgact
    22621 aaacatttgc tcatccactc gaaaatcttt gaaagatgtt cggatcgtcg tatacgcagt
    22681 atttctcaaa agcatcatgg caaaagtcaa agataactct gctatcgcat ttggcgaata
    22741 cgatggtaca cgggctactg tcataccaaa atcagctgcc gcttgtagat cgatatgatt
    22801 gactcccaca gtccgtgtaa aaacataacg aatcccatat tcctgcattt ttgcaagatt
    22861 ggtctcatct gctatacaat ttcccctcaa caatacagca tcatggtcct ttgctgacac
    22921 gatattgtca tgtgtcaaca gttcttcata aagactgaga tcataatggt aaatattcaa
    22981 tttttcaaaa aaatctatct cgttcggacg aacaccgtaa catgcgattc tcatactttc
    23041 ttcctccatt tcttatgaaa ataaacctat gccatgaatc atttgtaata caacgatcca
    23101 tacaggtgtc agtaccacag caaaaatagt tgacagtaag gatgcattgg aggctaaaag
    23161 tgcctcccta tcaaaactga tagcataggc tgctgccact gttgcagctg gtgtagccat
    23221 catgataacg attgttgcca gtgcttcaaa attgactggt agaatattcg ttgccgtcaa
    23281 aactgctaga atcacgatat tcaatgcagg tacaaatacc actttgacta gactgtaata
    23341 ccatgaagtt ttttcagatg cagctttttt gaagcttact tcacctaatg ttgcgccgat
    23401 tgctagccac gccaatggtg aacttaaacc agctaaataa tccatcggct gaaatagcca
    23461 cggtgcagtc tggtcaattc gcaaaaacgc tacttggctt atctctcctt ctgcacctgt
    23521 aactgacact tgtggcagat acccttggaa cagccaaatg aaaaggccgg caaaagtagc
    23581 gataatgatt ggattgacga acatcgcttt gatattttta gcttccatct tcaagccact
    23641 catttttatg tatccataag aatacaaaaa gattcggtag ccaatattga aaattgagga
    23701 atacatcacg ccgacaggac cataaatcgc actgacgata ggcgttccga aaaaggtcgt
    23761 agaaccaaag atcgtcagga cacgcaacgt tgtttgctta tcccctttat agcttaagaa
    23821 aaaaggtttt gaaactagaa taagaataat ataaataact aatccccaaa tcaagacatt
    23881 gattccttgc atcagtaatt ctgtattgat atcttgcatg aaagctcgaa atgccagtgc
    23941 tggcaaagcc actgttaaga cgactttcga tagaattttt ccaacagatt cagaaaaaat
    24001 cccctttttt ctacaaacaa accctaataa tataataaaa actgttgaag tgattgcact
    24061 gacaatcgac atatctgtca aagtcgatcg aaaaatgtca aataagttca tctttctcct
    24121 cctaattatg ttcatttatt cacaataaaa aaagctttta ttttgctaat acgtattaac
    24181 atttttaatt ttatctttac attgttactt attgaacaat aggaaattaa agaaactttt
    24241 gaaacttatg taaagtgatt tttactagaa cacaaaaaaa accttaaaac caaacttaag
    24301 aagtttagtt ttaaggttaa cttaaattat attatgcgtg gaaacgttcc acgccatcta
    24361 gataagttgc ttccaatgtc atatcagggt tcaatacgat aaagtctgca tcgcgtcctt
    24421 gagcgatttt tccacatgta tcatcgattt tacagctgat tgctggaatc agactagcca
    24481 tcatgactgc ttgttctggt gttgctaatc cccagtctac aacattttta attgcttctt
    24541 tcaatttcaa tatacttcca gctaagttgc cagattctag acgtgctgtt ccttctttta
    24601 ctactactgg aaattcgcct aaattgtaat ttccatcagg catcccaccg gccatcatac
    24661 agtctgtaat taatgcgaca tgatcatgtc ctgctttttc cattaggatt cccgcagcat
    24721 ttggatgtac atgatggcca tcacaaatca attcagaaaa gacatgttct aaagataata
    24781 acgcacccac catacctggt tcgcgatgat tcaatccacg cataccattg aaagcatgga
    24841 caaatacact tgcgcctgct tcaacagctt tttgcgcttc ttctagtgta gcattactgt
    24901 gtcctagaga aacaactact ccttcttcag tcacttgttt gacaaactct tctacacctt
    24961 gacgttccgg tgctaaagca atttttttga ttaaaccacc tgaagcttct tgccattcat
    25021 ggaaagtatc caaatcagga tccccgaaat aacttgggtt ttgtgcccct ttgtgttctt
    25081 ctgtgaagaa aggaccttca aaatagattc ctttgatttt agctcctggt gcttcctgat
    25141 acattttgcc gattgtctca gctacatctt ttaaacgttc tttgcttgac gtcaatgttg
    25201 ttggtaaaaa tgaagtcact ccacaagata acagaccttc agacatcact ttgatgcctt
    25261 ctgcatcatt atccattaca tcatgattca tatagccgtg aatatgtgta tctaccaaac
    25321 caggagcaat ccatttgccg ctttggtcaa tgatgttgac ttctccctca ggtagttctt
    25381 tggtgtattc accaaaaagt ccatcggtaa tttcaagata gcctgcatgt ttgacacctg
    25441 acgctaaaaa gaatttgtca gcatagataa aagttctcat tctattctct ccctttgttt
    25501 ttctacctct aaagtactct tatttagaga agaagtcaag aatggtctac accatttaca
    25561 aattttttga aatttgtttc acagcttgtg ctaagccttc atagaatgct gctctttctg
    25621 gttcttcttt acgcttgtat attaagcttt taagcacaaa taaatcattg aggtaatagt
    25681 agctattctt ctcttgagcc caatagattc cttgattcac ctgttctaac gcttcgtcga
    25741 tttcattttg atggaataag aaatttccat aattataaaa aatttgcgaa aattcacttt
    25801 ttgatcgttc atcagctgat tgatgcagca gttggatgct tcgactcaaa tagtagcgtg
    25861 cttcagccgt ttttcctgcc acaccatata tttttccgat acaactaatc agttgtattt
    25921 ctgtgtcaga aacatggatt ctttcttttt ggctagagta gcttaatgct tctttcaaat
    25981 aataaaggga ctgagagata ttttgacgca acgtgaattc gcaaacaccg agataataat
    26041 aatagcgttg aaagtcagtt gcttgataca gattttcaga aatatcagaa gattttagta
    26101 cttgttctaa cttccgataa tcacgttttt ggaaacaact atccaacagt tcaaataatt
    26161 tatcgtttgt ccgagtagtt tttcgagaga gattcatcac atgatcaatc gttaccccta
    26221 gccgttgaca aatctgcatc atcaccaata cattcggcag ttcctcatta ttttcgatcc
    26281 gacttaatac actttgtgaa caaatatcat gcgaaagcat tttttgcgtc attttttgtt
    26341 cttttcgaat ctctttaatg atcgttccaa aggactcgat taacgtttcc ataagtatcc
    26401 tccccaaaat atgcgtattc gcattctatt cgtattttac tttaggaagt cgcaaacttc
    26461 aagaaaagac ttgcaactaa ataatatact ttagttattt aagaaaactc cactagaaag
    26521 agagcctcag tgtgtttgtc tgtggccctc ctactgaaaa atttggtttt taaaatcatt
    26581 tttggcgata ggttgctagg aattctctca ttttcttagc tgtttgtttc aaatcatcca
    26641 ttttaggaag ataaacgatt cgaaaatgat ctggctggtt ccaattaaat ccaccaccat
    26701 gtacaagtag aatatgatgt tcatgtaaaa agtccaaaac gaatttttca tcatccaaaa
    26761 tattgaatcg ctttgtatca atttttggga atatataaaa agcagctttt ggttttacgg
    26821 ctgaaagacc aggaatatca ttgattgcat tatagatata ttctctttgt tcatagatcc
    26881 ttccgcctgg caggagcagc tcatcgacac tttgataacc gcctagcgcg gtttggataa
    26941 tttgctgaga caatacattg gaacacaaac gcatggagga caacatattc agcccttcta
    27001 tatagccttt gacgtgtgac ttatctccac ttaggaccat ccagcctact cgaaatcctg
    27061 ctacacgatg agatttggat agaccgttca gcgtaacaac gaacaaatca ggcgctaatg
    27121 tagcaatcgg aatatgttct agaccatcca tcactaagcg atcatagatt tcgtcggaat
    27181 aaataatcag gttattttgt cgagctactt caacgatttc ttctaataat tcttttggat
    27241 aaagtgcccc agtaggatta ttaggattaa tgataacaat agcttttgtc cgactcgtta
    27301 tttttgattt gatatcatca atatcaggat accattctgc ctcttcatcg caaatataat
    27361 gaacaggtgt gcctccagct aatgcaatag aagccgtcca caacggatag tccggcattg
    27421 gaaccagtac ttcatctcca ttgtccagca acccctgcat acacatcgtg atcaattcgc
    27481 tcactccgtt gccggtgtag atatcattga tcgtcacatt cggaaaatgt ttcagttggc
    27541 aatattgctc aattgctttt ctagcagaaa agatcccctt ggaatctgag tagccttctg
    27601 agtcacgggc attcatgatc aaatcacgaa tgacttcgtt tggtgcttca aatccaaaag
    27661 gtgcgggatt tcccgtgttc aattttaaaa tactaatgcc ctcttcttgc atccgctccg
    27721 cttcttctag aacgggaccg cgaacatcgt aactgacacc ttctaatttg ttggattttt
    27781 caaattctct catcacttag ccaatccctc atttcaaaaa gttagaactt tccaaatttt
    27841 ttgttattta ctatttcaat atcatactcc atcctagaaa attttgccac ttatttagga
    27901 aaaacgtaag tattaaaaaa acacaaacaa gcgttgagaa cttaattgtc atgatagtca
    27961 ttccatagat tcgctgccca atccattgca attccacaaa tgattcctag cataaaacca
    28021 agcaaaaaac gtccgaatgc aagtccaatc aatacaccta agatcattcc cagtcctgaa
    28081 aattctccgt catatttctc catcttaata agtcctccca tttttgagct tgacaactat
    28141 gtaaaacctc gctatcatta gtgtgttatt attacgcaga tgtgttggaa ttggcagaca
    28201 agcatgattg agggtcatgt gagcgttagc tcgtgtgggt tcgagtccca tcatctgcac
    28261 tacaactcgt gaagttaatt ttgcttcacg agtttttttg tttgaacgtt tctttatgcc
    28321 attatataca tatcactgta tcctttacaa aaagaacgta caatcatgta aacagcctga
    28381 ggtgagtata tgaaggtcgg aaacaagcta ctcgtagaaa cttgcaagtg ttaaaacaat
    28441 taatcgaaaa acgagtaaaa tccctcacct aatactaaag cgagggattt tttgtatatt
    28501 atctgtttat caccgttatt ataaaggtac aaataccaag cacggttaat ccaaattgca
    28561 taaattcatt tttttgtaca ctcatgcttt tcattagctc tttaactgcc attagtacta
    28621 agatggcgat aacaacataa agtatatagt acgtccgcat tccggaagcc catactgtgg
    28681 gagaaaatcc cataattaac cttgaacaaa atcccattat catcaaaata actaaaaaaa
    28741 tagaagtttt cttattgtca aaacttaaat aaattccaac aattaaacat agtaataatg
    28801 ccaagactac taaagtagct atccaagtac ctggataaaa aagtgacagt ttcgttccta
    28861 actctgtaaa gagattattc aggttactac tactccaaat cattgccctt ttatttccat
    28921 tgacgtaagt aaagctttga cccattgtat taccaaaata aataatcagg tttaagaaaa
    28981 acggtaatgc agtcaatata cgcacataat agttttgaca tttcctatat gttagaagga
    29041 aaattaagaa aaatagcaat aaaaataaga tattcatgtc taaaaaaaac ggctttccaa
    29101 atgatgaaat acctaaatct aacttattaa gaaagttgaa atttttatat tcaggaaacc
    29161 atttattaat ttcatgtgca gcacgtaatg cattccctgg agttgtcaaa gagaaaatta
    29221 attctgctaa gcttattatt gaaaatactg ataacttata attatatcgt ccattgacaa
    29281 tcaaatataa actaactata cttgttagaa caaaaaaaca ggcgttgact tgttcttgat
    29341 tagttaaaaa tatcaataaa ggaatactta cccaatatat ttttctattt atttcttctc
    29401 ctcttaagag ttgaaaaaac ggataaaaag ttagtaaact aaatgctact ggccactgat
    29461 agttcaaggt ggttgctctc caaccggttt cccccattac tgtcaatggt attaaacagt
    29521 atatagagca aaccaataat aaatttttaa catttatttt ctcaaaaaca ta
//
LOCUS       DAYNVV010000031        28862 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.031, whole genome shotgun sequence.
ACCESSION   DAYNVV010000031 DAYNVV010000000
VERSION     DAYNVV010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.031"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            4..243
                     /locus_tag="ACGXWR_001566"
     CDS             4..243
                     /locus_tag="ACGXWR_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803140.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            310..519
                     /locus_tag="ACGXWR_001567"
     CDS             310..519
                     /locus_tag="ACGXWR_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803141.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVAQYINDMQLT
                     GKEKACLLGSMKNFEQLRRTYRIHF"
     gene            579..1250
                     /locus_tag="ACGXWR_001568"
     CDS             579..1250
                     /locus_tag="ACGXWR_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFK0803142.1"
                     /translation="MKKWLFGFLGVTLIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPGYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            1303..3279
                     /locus_tag="ACGXWR_001569"
     CDS             1303..3279
                     /locus_tag="ACGXWR_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFK0803143.1"
                     /translation="MAINRYVKKAGMLVGMLGIIAGCFQGYQVHAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GKGLSYVAEKADIKVTNNDGSVVLKENTDYKIENSDSGFVIDFIVNNGQVSDTVANLH
                     GQDLKMTYNMFVNDSAEIANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQSYVLISCLLLGAGGLSAVVYFKKKA"
     gene            3292..4047
                     /locus_tag="ACGXWR_001570"
     CDS             3292..4047
                     /locus_tag="ACGXWR_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFK0803144.1"
                     /translation="MIIRKPPKRRVMHKLMIFFWLLSAVAVYLIPVVETNVAKFQQQQ
                     RILAIENLEKTDSSLDVAKIELGDPVGVLTIPSISLKLPIYDGTSDKILENGVGITEG
                     TGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGQKFFIKVNEEQHAYQIYRIEEVK
                     AEELQKNYLDYLMPEKDQDRITLMTCTPKGVNSHRFLVYGERVSFSKEDLKLQKKAKN
                     RKSISLDWRLALLFAFFCVPIIFIYKKIRRRSE"
     gene            4044..4868
                     /locus_tag="ACGXWR_001571"
     CDS             4044..4868
                     /locus_tag="ACGXWR_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFK0803145.1"
                     /translation="MNKRKWLFVCVAALFSTVAYSQLSFADSSDSSTTQTIDNSITAP
                     SETDSSENTTEETADSNISFTESTNPTSESSSETSEKPQDVEDTQVIKQAIHIQKIIS
                     SNQINNQGSQVAQQEGINGAKFIVYDITNILEEMSQDDNEKNQSVEIIESKLKDRAKK
                     LSYDQLKKVAEGETKTIDDQEGVIEFSIEVPANKKQAYYIVNESSPENISNSEDIVLL
                     TPVSNEKGEFLTDVWLYPKSEKSEPKEEIKKVVSTGVKKNFFENCWEFFAQLFFDN"
     gene            4878..5126
                     /locus_tag="ACGXWR_001572"
     CDS             4878..5126
                     /locus_tag="ACGXWR_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803146.1"
                     /translation="MKIIRILVFNLSFLAATILCCGLIFSQLSIYPRYQRLFIHFLNI
                     QCASMPLEVIKKLLINPIFMVSLVLLTGLVTWVLGKKE"
     gene            5169..7268
                     /locus_tag="ACGXWR_001573"
     CDS             5169..7268
                     /locus_tag="ACGXWR_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HFK0803147.1"
                     /translation="MENKIHCTTGRVITLVLFLFLLLFARGTAVQALEKVDPSQIKEN
                     NNLVLYHDSDSLRNIEVTGINGFKILDEYSTKKQKVLAWPKVKDLKSTSKIVAHYQKV
                     GTYLGKEIDCDVTFSNFVAHAGVNQDGLAKTINGKKYYNYLLFDKNIYRGFFMQSINV
                     MNAKLEFKYAGTKTKVALSEPQPEIQSKMRSMRAAGIDLNDTFLSIYSLNGQYQQRVS
                     WYNDNNESVGERNIDMREFVGYEKMGSLPYFVTTDTACAEYKAPALSTNNLTSKVVGG
                     RAEKAYSSNDHFTDVVGADTYHRSGVTYTLQGASPTFMIGANTNSMMFSFDTALLWTP
                     QPSKPTKEVFNKANTEEAAHNIDKKVIPQGSDVYYHIHQKFDALTVNTMNKYKSFKIT
                     DTFDSKNFDMVSDGKNYDGALWYVEANGTWKKADTGGKLTVSGNTVTYTASDSFLANA
                     ANYGRDYILQLHMRAKNDAKGIAPNVATVTFNNDPNKGTQKTNTVENYFSLKPNKKVE
                     QDGKDVDGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDIASDHYKQFSIQDPVED
                     RLTYKEGSARVIDMSTGKDITSEGTLTYDSNSRTLKWEASADFLSKNLLDGREIQLIF
                     TAKTPLNEELDIDNQAKVSVESIEKATNVVTIGVKPNLPQIIVPKTGSNHLVLTVIGS
                     ILFLTLASLGYVVLKLK"
     gene            complement(7306..9363)
                     /locus_tag="ACGXWR_001574"
     CDS             complement(7306..9363)
                     /locus_tag="ACGXWR_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HFK0803148.1"
                     /translation="MKLFNPKTVLAIGTFAASLSLAGSVDAASTNVMYRLYNPNNNEH
                     FYTSSKKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVKSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNKLDSAYKGLKKKPVPTVNKAELQALYNRVKSTAKGDFTEESWNNFQTAL
                     SNAKKVLDDSKVSQTQVNNAKNSLDAAFKGLQHKPETPKEYTVTINHIDNQTGQVIAT
                     DQAKVTSGSTYTAKAKAFKYSEGAKDNFSYKVIGNDTQSKTITGNTTITFNYNQVHQI
                     NLLCNNNYKNEGRVNILKEQIVNVTHGDSVTLTAPSIQGYVLDDRVEPTNSVTLNNVT
                     ESQNYIFNYTRKFNVTVNHVNADTNAVLSSESKTVYEGDSFATPWKNMTDQNYFLCRN
                     DDPTVTVDKNGQRSINNVDQNKTITFKYKKISLDELRNFMRQKELAWLNDYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENISQTGLYID
                     DLLSDDGAIDAMVGWKNSPAHNANLLYNNQSILGLGHNFVVDSAGRIGVDNVFISANP
                     IFK"
     gene            complement(9477..9689)
                     /locus_tag="ACGXWR_001575"
     CDS             complement(9477..9689)
                     /locus_tag="ACGXWR_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803149.1"
                     /translation="MYADKKKIEWLLFDSGKSVRSISIESGVPLTTVSDLANKRSSID
                     NMRFINAMKLNKLAEEIVDINTSTNK"
     gene            9876..10343
                     /locus_tag="ACGXWR_001576"
     CDS             9876..10343
                     /locus_tag="ACGXWR_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803150.1"
                     /translation="MKKKQLWFVSMFAIFFIILSGCSSNKKSEAKEDNSLLQPGTVWK
                     EEVGGLIHNLKIIDDTTWEYSESVWHPDPVQITVKRQKDYEGLERYKIVDSAGIREFI
                     NKPDSLFIVVPYEKDGVKKIIFLGSSKDEKRTKEKLIHDGSELNKYKLQKTSE"
     gene            10340..10582
                     /locus_tag="ACGXWR_001577"
     CDS             10340..10582
                     /locus_tag="ACGXWR_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HFK0803151.1"
                     /translation="MIASLFIYPEGGITVAKVKTPFEKAASKILERRGVSEIQWKKEV
                     LEKAQFDLLRGKDKDLEEYIYQREREKLVFDEIIKH"
     gene            10600..10902
                     /locus_tag="ACGXWR_001578"
     CDS             10600..10902
                     /locus_tag="ACGXWR_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803152.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAVAA
                     VASIALGGIFFFFGRRGAENGKTHVGYVLLGVGVILAAASIVVSMFSMFGQTPQGL"
     gene            10974..13028
                     /locus_tag="ACGXWR_001579"
     CDS             10974..13028
                     /locus_tag="ACGXWR_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803153.1"
                     /translation="MFFTISGNAKLDKELIRKATKKVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGPLDYQISEGFYPTLIDLIR
                     LDVFKDTDETMSVEESYRNEKLLQVLEEELESDQRKVNQVSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETDEVEVDPVEA
                     NEESTWTEGDFQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKVKEELNKEEQRVIEEEVQKVKERYEKKRDNAYSLCVE
                     KINNFTKTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKHEQIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLEIRKREQD
                     LAEQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSESNE
                     VK"
     gene            13028..15640
                     /locus_tag="ACGXWR_001580"
     CDS             13028..15640
                     /locus_tag="ACGXWR_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HFK0803154.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPENEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHKGK
                     KFHEERVKVGYRGFCEINFDCHLEQGDHVCLKYNHQGKQYVAWYEFSQKVLKDEEGKI
                     VYRKKRGETHLPELEKEAVLTLDEKKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSFENETAKKLLIQFYEEQATDRLQEYVEKLIKNEEISEMI
                     RKRLLLEAEKAVKE"
     gene            15637..18015
                     /locus_tag="ACGXWR_001581"
     CDS             15637..18015
                     /locus_tag="ACGXWR_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFK0803155.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PDQAKKMSESSDISTVQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYRRY
                     ISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSAIE
                     DISQSFLLLAFTILELRIYTLMLSGIGDLHAVGKINGFLYVVALIVLTIALFKGSQSV
                     TKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGFGH
                     RKDITHDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGTVE
                     DLTEKAKDTLEEKLDGTRAKEFAEAVKNPSEALEKQKEKASAVKEGLKDAYGEGQVNA
                     AVKANTTSEKENQEGAAIPSAKDHQDELHSNENSIGEKDSEEGQHGQLPKTDPEQYRY
                     KSNINSENEKRISDLPKRNQEVQTDEDSIDLPNDNGIEVGTEKSTKIGLPKTQNLPMK
                     DSRLNQFKENDQSFVHQSPAGTVQMKSSRLPENGNLTTVSYNLAESGETENASVQNIV
                     TKEAAPKPINKVHNGYRPANVAFTAPTKINVTRETKNRNNELKEQLLKDIKP"
     gene            18076..18618
                     /locus_tag="ACGXWR_001582"
     CDS             18076..18618
                     /locus_tag="ACGXWR_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803156.1"
                     /translation="MEDILIATFITALGAFLTIFVVTIKGFKDTDSLQKDHQSILDGQ
                     KTHTESIIVHLSEGFTYLKDAMPTFTVKLTEIFHSVEQISSELKEQRQQKDRQLGSLN
                     FRQETIQESLENVNRLNDEMQRVHLENEELRAQNYDLIQKKRNLEQKIVELKEENRQL
                     NYQLRRGKNRSRDLGNELEL"
     gene            18696..19028
                     /locus_tag="ACGXWR_001583"
     CDS             18696..19028
                     /locus_tag="ACGXWR_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803157.1"
                     /translation="MDKYIHMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWLAIALVIVWRPYNNPGQRQIFAIIESIFFTDKNHYHALDPNRNY
                     HGTYKEDE"
     gene            19029..19622
                     /locus_tag="ACGXWR_001584"
     CDS             19029..19622
                     /locus_tag="ACGXWR_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803158.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            19644..21338
                     /locus_tag="ACGXWR_001585"
     CDS             19644..21338
                     /locus_tag="ACGXWR_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HFK0803159.1"
                     /translation="MLDVIKTAFSTQSNQKVIDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLAFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNGATCSAVKSCGLQVV"
     gene            22026..23903
                     /gene="ltrA"
                     /locus_tag="ACGXWR_001586"
     CDS             22026..23903
                     /gene="ltrA"
                     /locus_tag="ACGXWR_001586"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFK0803160.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            24034..24411
                     /locus_tag="ACGXWR_001587"
                     /pseudo
     CDS             24034..24411
                     /locus_tag="ACGXWR_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            24411..25616
                     /locus_tag="ACGXWR_001588"
     CDS             24411..25616
                     /locus_tag="ACGXWR_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFK0803161.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDP
                     LPFLNSSKK"
     gene            25632..26276
                     /locus_tag="ACGXWR_001589"
     CDS             25632..26276
                     /locus_tag="ACGXWR_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803162.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPTDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            26287..27093
                     /locus_tag="ACGXWR_001590"
     CDS             26287..27093
                     /locus_tag="ACGXWR_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803163.1"
                     /translation="MSKKKGERQRFKKRKSYLRWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            27115..27345
                     /locus_tag="ACGXWR_001591"
     CDS             27115..27345
                     /locus_tag="ACGXWR_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803164.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            27891..28166
                     /locus_tag="ACGXWR_001592"
     CDS             27891..28166
                     /locus_tag="ACGXWR_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803165.1"
                     /translation="MDLLIRNIEEKYINKIDKRCEELTVKTGKKWSRNQYLKVLIEND
                     FDHALLNYKKDQFDRLLEKFVDIQTYNTKTLEEYIATNNQLIGLLIE"
     gene            28208..28630
                     /locus_tag="ACGXWR_001593"
     CDS             28208..28630
                     /locus_tag="ACGXWR_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803166.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAEERVE
                     GKIKSNQTKKYSSKLKKPVNESVHTRVDPFDPTKILKR"
     gene            28649..>28862
                     /locus_tag="ACGXWR_001594"
     CDS             28649..>28862
                     /locus_tag="ACGXWR_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803167.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKT"
BASE COUNT        10493 a         4472 c         5860 g         8037 t
ORIGIN      
        1 tagatggcgc gaccagtttt agaggcgatg gatatggata ctttgacaaa aggaaggtat
       61 gtacagctgt tagctcgtgg ttattcacct aaagaagtat tcaaagcctt atctaaagga
      121 acagatatgg aaaaagaaag attgcgaaaa gaattcgatt attggagaac ccataatgga
      181 atcaaggatt tgaaaccagc acggccagta attaaacgaa agaaaaagat aacccaagac
      241 tgaagtgtag agcgtatgtg atcataggct tttttatttt tgcaaaaaac aaggaaggta
      301 ggaaaactca tgaattatga agaaatcgaa aacagaaaaa aagtgtcgaa agaaatggaa
      361 gaaaagttac taaaaacgat gaagcaaaaa caccttaaaa gattatctgt cgcgcaatat
      421 atcaatgata tgcagttaac aggaaaagag aaagcttgtt tgttaggttc aatgaaaaac
      481 tttgaacagt tgagacgaac ttatagaatt catttttaaa actttttcta tggaaatgag
      541 aaaaagtttt tttgttttgt ctgaaaggag gcagatggat gaaaaaatgg ttatttggtt
      601 ttttaggagt cactttaatc gtcttttgca gtgtgtttgg ctatgttagc taccaaaaac
      661 atgaaggaga ggtgtttaag caaaatatag aaaaaaagat gcccgtagat caaatcaatg
      721 cacatgcaaa gagttataag gaggatgcaa cgaacgtcaa taatgatatg tctttggggc
      781 aaatgttgtc catacaaaaa gaagcaatcg aaatgggcgt caataaacaa gtatttgcac
      841 aaattcagat tcctgcactt ggtttagcat tgccaatttt taaaggggca aatcaataca
      901 ctttgagtct tggagcggct acttattttt atgaagatgc cgaaatgggc aaaggaaact
      961 atgtcctagc aggtcataac atggaaatgc caggtgtttt attttctgat attcaaaagt
     1021 tgtcattagg ggaggtgatg gacttagtta gtaacgatgg cgtctatcgt tacaaggtaa
     1081 cgcgtaaatt tatcgtacct gggtacttta aattaatcga tggcgttcct gaagagaact
     1141 ctttcttgtc tttgccaaag aaaggagaga aacccttatt aacgttgttt acttgtgttt
     1201 atacgtcaca aggaaaagaa agatacgtgg tacagggaga gctacaataa caaggtttta
     1261 atcaacgcga gtcgttgaaa tatgaaatga ggagagtaaa aaatggcaat aaatcggtat
     1321 gtaaaaaaag ctggaatgct tgttggaatg ttaggaatca ttgcaggctg ctttcagggg
     1381 tatcaagtac atgcagaaga tgtcacgcaa aaaacaccac cagagaaggt caatatcacg
     1441 gttcataaat taatgtacga tcaaggaacg caattgaatg ttgatattga cgggatcaaa
     1501 aacgatggtt atacgcacga tcaatatcct acaggtgtaa cgaaatacaa caaggcagat
     1561 tatggtgatg ttgagtttac gttaggaaat attacggatc aagtattacc gagagaagat
     1621 tctgatctaa ccaacgcgaa agtggacgag attgtacaag atgtagaaga caagggatct
     1681 aacagtgagt acgtcaagaa tgcaaccaac aaaattactt cagctgtaga tgaaaatggt
     1741 gagatcactt ttactgatca accagcctat gtcaattcca aagggaatgt atatgtggtt
     1801 tatgaaagta aatccgctgc tggattagtc acacaaaaag caaaaccaat ggttgtgatt
     1861 gcgccaatga cagataaaac aggatcagga tttttaaaaa atattcattt gtatcctaag
     1921 aacattgttt ctaagttgag ttttgaatta acgaaatttg gtgacgatgg cgcagaccaa
     1981 agcaaacaaa cccttttaaa aggggcaaaa tttgagttat acaagggcga acctggaaaa
     2041 ggaacaaaat tgggtgatct tgtatcggat gatcaaggaa agctgactgc gactgatttg
     2101 acgttaggaa aatactattt tgtggaagtt ccttcggaag ttgtagtggg atcagatcaa
     2161 gaaccaacag cagatcaata tttattaggc gcagacgctc gcaacgatgc gcacaataaa
     2221 ttaacctttg aaattacgaa tgatggcgtg acaagtgact taaaagcttc atacgtaaac
     2281 tataaagcac cagtgatcga taaaacagta acaaatggaa caggacaaga acattctttc
     2341 caaattggtg acgcagtaaa ttatcaagga acgattcata ttccaacaga cattgcaggt
     2401 ggcgcagacg gtatcacagt aaacggtgtg aaaagcgaaa cttctcctta cagtgtattt
     2461 aaatggggag atacagcagg taaaggactt tcttatgttg ctgaaaaagc agatattaaa
     2521 gtaacaaata atgatggttc agtcgtatta aaagaaaata ctgactataa aatcgaaaat
     2581 tctgatagtg gttttgtgat cgattttatc gtaaataatg gacaagtaag tgatacagtt
     2641 gcgaatttac atggtcaaga tctaaaaatg acttataaca tgtttgtgaa tgatagtgct
     2701 gaaatcgcaa atccattaac aaatagcgtg gatttcgttt ataacaataa tccatttaat
     2761 caggaagaac accacgaaaa aacgaaagct gacgttgtga cttatggcgc aaaattctta
     2821 aaagtcgata gcggcctatt tggaacaggt atcaaagcaa caccgcttga aggcgcagaa
     2881 tttgcagcta agaatgcaga aggtaagtac tacggtggac ttactgatac agataaagat
     2941 ggtgtcaaag aagcagtttg ggtagacgat gtagcaaatg cagcaatcct aaaatcagat
     3001 aaagagggtc attttgaaat cactggttta actgaaggag attactcact ggaagaaaca
     3061 aaagctcctg aaaactatca aaaattaaca aaagagatct ctttcaaagt agacaaagat
     3121 tcatacaaag aagaaaaccg aatcacgatc aaaaataatc aaaaagcttc cgtaccaatg
     3181 actggtagca acggtttcca atcttacgta ttgatctctt gcttgttgct aggagcaggg
     3241 ggactttctg cagttgttta ctttaagaag aaagcctaga aggatcagct aatgattatt
     3301 cgtaagcccc caaaaagaag agtcatgcac aaactgatga tatttttttg gttgctgtcg
     3361 gcagtagcag tctatttaat tccagttgtg gaaacaaatg tagcgaaatt tcaacaacag
     3421 caaagaattt tagccattga aaatcttgaa aaaacagatt cttctttgga tgttgcgaaa
     3481 atagagttag gcgatcctgt tggtgttctt acaattccaa gtatttcttt aaaactacca
     3541 atttatgacg gaacttccga caaaatttta gagaatggtg tagggattac ggaaggaact
     3601 ggcgatatta caggaggaaa cggtaaaaat cctttaatcg cggggcacag tggactttat
     3661 aaagataatc ttttcgatga tttgccttca gtaaaaaaag ggcaaaaatt ctttattaag
     3721 gtaaatgaag aacaacatgc ctatcaaatt tatcgaattg aagaagttaa agcagaagaa
     3781 ttacaaaaaa attatttaga ttatcttatg cctgaaaaag accaagatag gatcacgtta
     3841 atgacatgca caccaaaagg tgtcaactca caccgctttt tagtgtatgg tgaacgagtt
     3901 tccttcagta aagaagattt aaaactacag aaaaaagcaa aaaataggaa atcaatttca
     3961 ttggattggc gattagcact gctattcgct tttttttgcg ttcctattat ttttatttat
     4021 aaaaaaataa ggaggagatc ggaatgaata agagaaaatg gctgtttgtt tgtgtagcag
     4081 ctctcttttc tactgtagct tattcgcaac tgtctttcgc tgacagcagt gatagtagta
     4141 ccactcaaac aatagataat tcaattactg caccaagcga aacggacagt tcggagaata
     4201 ctacagaaga aacggcagat tcaaatataa gctttactga atcaacgaat ccaacgtcag
     4261 aaagttcttc agagacttca gaaaagccgc aagacgtaga agatacgcaa gtgatcaagc
     4321 aagccattca tattcaaaaa attatttctt cgaatcaaat caacaatcaa ggcagtcaag
     4381 tagcccagca agaaggtatc aatggcgcga agtttattgt ctacgatatc acgaatatct
     4441 tagaagaaat gtcacaagat gataatgaga aaaatcaatc tgtagaaata attgagtcaa
     4501 aattgaaaga tcgagcaaaa aaactttcat acgaccagtt gaaaaaagtg gctgaaggag
     4561 aaaccaaaac gattgatgat caggaaggcg tgattgaatt ttccattgaa gtacctgcaa
     4621 acaaaaaaca agcatactat atcgttaatg aatcaagccc tgaaaacatt tcaaacagtg
     4681 aagatattgt tttattgaca cctgtttcaa atgaaaaagg tgaatttttg acggatgttt
     4741 ggttataccc taaatcagag aaatcagagc cgaaagaaga aattaaaaaa gttgtgtcaa
     4801 ctggtgtaaa gaagaacttt tttgaaaatt gttgggaatt ttttgctcaa ttattttttg
     4861 ataattagga tgaaatgatg aaaataataa gaatattagt ttttaatcta tcctttttag
     4921 ccgcaacaat attgtgttgc ggtttaattt tttctcaatt atcaatttat ccaagatatc
     4981 aacgattgtt cattcatttt ctaaacattc aatgtgcttc catgccatta gaggtgatta
     5041 aaaagctctt gatcaatcca atttttatgg ttagtttggt tcttcttaca ggattggtaa
     5101 cgtgggtatt aggaaaaaaa gaatgaaaag cttacgatcg tttaaaaaaa tattagatgg
     5161 agggcattat ggaaaataaa attcattgca ctacgggaag agtaattact ttagtgttgt
     5221 ttttgttcct tcttcttttt gcgaggggaa ctgcagtcca ggccttagaa aaagttgatc
     5281 cgagtcaaat caaagaaaat aataatctgg tgctttatca tgatagtgat tcattgagaa
     5341 atatcgaagt aactgggatc aatggattta agatactaga tgagtattca actaaaaaac
     5401 aaaaagtact tgcttggcca aaagtcaaag atttgaaaag tacgtcaaaa atcgttgccc
     5461 attatcaaaa agtaggtact tatctaggaa aagaaattga ttgtgacgtg actttttcta
     5521 attttgtagc gcacgctggg gttaaccaag acggattagc taaaacaatt aatggcaaaa
     5581 agtattataa ttatttgctc tttgataaaa atatttatcg aggatttttc atgcagtcaa
     5641 tcaatgtcat gaatgcaaaa ctagaattta agtatgcagg aacaaaaaca aaagtagctt
     5701 tgagtgaacc acagccagaa attcaatcaa aaatgagatc gatgagagca gctggtattg
     5761 atttaaacga tacatttcta tccatttaca gtttaaatgg acagtatcag caacgtgtgt
     5821 cttggtataa tgacaataat gaatctgtcg gtgaacgtaa tattgatatg agagaatttg
     5881 ttgggtatga aaaaatgggt agcttacctt attttgtcac aacagataca gcatgtgcag
     5941 aatacaaagc tcctgcgtta tcaacaaaca atttaacttc aaaagtagtg ggaggacgtg
     6001 cagaaaaggc ttatagctcg aatgatcatt tcaccgatgt tgtaggagct gatacttatc
     6061 acagaagtgg tgtaacgtat acgcttcaag gcgcttcccc aacattcatg attggcgcaa
     6121 atacgaatag tatgatgttt agctttgata ctgcattgct atggacacca caaccatcga
     6181 agcctacaaa agaagtgttt aacaaagcta atactgaaga ggcagcacac aatattgaca
     6241 aaaaagtgat tccacaagga tcagatgttt actatcatat tcaccaaaag tttgatgcat
     6301 taacagtcaa cacaatgaac aaatacaaat catttaaaat cactgatacc tttgacagca
     6361 aaaattttga tatggtatcg gatgggaaaa actatgatgg cgcattgtgg tatgttgaag
     6421 cgaatggtac ttggaaaaaa gctgatacag gaggaaagtt aactgtatca ggtaatacag
     6481 tcacttatac tgcttctgac agctttttag ctaacgctgc aaattacggt agggattata
     6541 ttttgcagct ccatatgaga gcaaaaaatg atgcaaaagg aattgcacca aatgtggcta
     6601 ctgtaacgtt taacaatgat ccgaacaaag gaacacaaaa aacaaataca gtagaaaact
     6661 atttctctct taaaccaaat aaaaaagtgg aacaagatgg gaaagatgtt gatggtcgaa
     6721 atgatggtaa aaaaggaacg cctacagctc ctttaaatgc aggatctgaa gtacaatatc
     6781 tagtcacaca aaaatggcat acaaaaggtg tagacattgc ctcagatcat tacaagcaat
     6841 ttagtattca agatccagtg gaagatcgtt tgacgtataa agaaggttct gcgcgagtga
     6901 tagatatgag tacaggaaaa gatattactt cagaaggtac actaacctat gatagcaatt
     6961 caagaacgct gaagtgggaa gcttccgctg atttcttaag taaaaatctt ttagatggac
     7021 gagaaattca gctgatattt acagctaaaa ctcctttgaa tgaagaattg gatatcgaca
     7081 accaagcaaa agtttcagta gaaagtattg agaaagcaac taatgtagta acgattgggg
     7141 taaaacctaa cttacctcag atcattgtgc caaaaactgg atcgaatcat ttagtgctaa
     7201 ctgttattgg aagtatatta tttcttactt tagcatcatt gggctatgta gttttaaaac
     7261 tcaaataaat ataaaaacaa ggctgagaat cagccttgtt ttcttttatt tgaagattgg
     7321 attcgcacta ataaatacat tatctacgcc aattctacca gcagagtcaa ctacaaaatt
     7381 atgacctaat ccgagaatac tttggttatt ataaagtaaa tttgcattat gggcagggct
     7441 atttttccat cctaccatgg catcgatagc accatcgtct gataaaaggt catcaatata
     7501 cagcccagtt tgacttatgt tttctccctt agcaccgtag cagcctaagc tttccaataa
     7561 atcttggaaa gtaccaccac cagggcgata gtgactgaag ctgacttgta attctttagc
     7621 tcgaatatct gcagcctgtt gaacaatatc attgaattgc attggggcaa caccattttg
     7681 ttggcgataa tcatttaacc aagcaagttc tttttgacgc ataaagttac gtaattcgtc
     7741 taatgaaatc tttttatatt tgaatgtgat tgttttattt tgatcgacgt tattaatgga
     7801 tcgttggccg tttttatcca cggtaacggt aggatcgtca tttctgcaca agaaataatt
     7861 ttgatcagtc atgtttttcc aaggagtagc aaagctatcc ccttcgtata ctgtttttga
     7921 ttcactagag agaacagcgt tggtatcagc atttacatga ttaacagtca cattaaattt
     7981 acgagtgtag ttgaaaatat aattttgact ttcagtcaca ttgtttaagg ttactgaatt
     8041 tgttggttct acccgatcgt ctaaaacata tccttgaata gaaggagcag ttaaagtgac
     8101 actgtcaccg tgagtgacat tgactatctg ttctttcaaa atattaactc gtccttcgtt
     8161 tttgtagttg ttattgcaca acaaattgat ttgatgcact tgattataat tgaatgtgat
     8221 tgttgtatta cctgtgattg ttttgctttg agtatcatta ccaatcactt tgtagctaaa
     8281 attatcttta gcgccttcgc tatatttaaa tgcttttgcc ttagcagtgt aagtagaacc
     8341 agaagttact tttgcttgat ctgtagcaat cacttgacct gtttgattgt caatatggtt
     8401 aatagtaacc gtatattctt ttggtgtttc aggtttgtgt tgcaaccctt taaatgcagc
     8461 atcaagacta tttttagcat tgtttacttg tgtttgagaa accttagaat cgtctagtac
     8521 ttttttagca ttggataaag cagtctgaaa attattccaa gattcttctg taaaatctcc
     8581 tttagcagtt gattttactc ggttgtataa agcttgtaat tcagctttat tcacagtagg
     8641 aactggtttt ttctttaatc ctttgtaagc agaatctaat ttatttttgg cactatccac
     8701 ttgcttttga gtcgcttttg agtcatttaa cactttctta gcattgttta aagcggtttg
     8761 gaatgcgttc caggtattgt cggtatagtc accttttttc gttcccttaa cgctcgtata
     8821 aagagcttct agagccgatt tattcacttt gggtttagag gtgtcagcgc cataccaacc
     8881 gataccttcg tatttccagc catagtcttt ggttaaccat tgtacttctt tccaacttgc
     8941 agtgtagtga tgtgagccag attttacacc aggaaggaaa aggcggtaga tcggtttatt
     9001 atttttttcg gcagaacgcc aggcaggccc ttcataagtc cagccgtaat ttttagtcaa
     9061 ccatttcact tcatcccaac tagctgtgta atggtgatca cgaagacctt tattgtacaa
     9121 acgatagaca agatggccac cgctagtcgg tgcttcccag gcggggcctt cataatttcc
     9181 ccattttatc tttactagat ggtcacgttc ttttttgcta gaggtgtaaa aatgttcatt
     9241 attatttgga ttgtaaaggc gatacatgac gttagttgaa gcagcgtcaa cagatccagc
     9301 aagactaagt gaggcagcaa atgttccaat agctaaaaca gtttttggat taaataattt
     9361 cattttttca actcctaaat ttaattaaaa atgtttacat gattattata tatcggctaa
     9421 ccgatatagt caataaaaaa taagaaaagc cttatataat tttggctttt cttattttat
     9481 ttgttagttg aagtattaat atcaacgatt tcttcagcca atttatttaa tttcatagca
     9541 tttatgaatc tcatgttgtc tatactagag cgtttgttgg caaggtcact tactgtagtt
     9601 aagggtacgc cagattctat ggatatagaa cgaactgatt taccactatc aaacagcaac
     9661 cattcgattt tctttttatc agcgtacatt tcaatgctcc ttcttgtttt ttctttatta
     9721 tagctctttt ttgtaatgaa tcacaatatc aagagaaaaa ttttctatag aaaggtggat
     9781 ttttatgagt attcgttctc cgtgtatcca aatgaggttt gttgctactt tcgttatttg
     9841 atatactaaa aataaacaac gaaagaagga ataaaatgaa gaaaaagcaa ctatggtttg
     9901 tctctatgtt tgcaatattt tttattattt taagtggatg ttcaagtaat aagaaatcgg
     9961 aagctaaaga agataatagt ttattgcaac caggaactgt ttggaaagaa gaagtaggtg
    10021 gtcttattca taatttaaaa attatagatg atactacctg ggaatattct gaaagtgtat
    10081 ggcatccaga tcctgtacaa ataacagtta agaggcaaaa agactatgaa ggtttagaaa
    10141 gatacaaaat agtagattct gcaggcatta gggaatttat aaacaaacct gattcattat
    10201 ttattgttgt tccctatgag aaggatggcg taaaaaaaat aatttttctt ggatctagca
    10261 aggatgagaa gcgaacgaaa gagaaattaa ttcatgatgg atcagagtta aataaataca
    10321 aattacaaaa gactagtgag tgattgctag tctttttatt tatcctgaag gaggaatcac
    10381 agtggcaaaa gttaaaacac cattcgaaaa agccgcgtct aaaatcttag aacgccgtgg
    10441 tgtttctgaa atacagtgga aaaaagaagt tcttgaaaaa gcacaatttg acctattacg
    10501 aggaaaagat aaggacttag aagaatatat ctatcaacgt gaacgtgaaa aacttgtatt
    10561 cgatgaaatt attaaacatt aaaaggagcg aataatctta tgtttgaatc aattacaatg
    10621 aattttttaa ctcaaccgaa agtagtagct gcagttgata tttttagagc attacaaact
    10681 gccgcaacta gtttgaaaaa taatctgatg atttttgctg ctgttgcggc agtggcttcc
    10741 attgctcttg gaggtatttt cttcttcttt gggcgaagag gagctgaaaa cgggaagaca
    10801 cacgtaggtt atgtattgtt gggggtagga gttattttag ctgccgcttc tattgtagtt
    10861 tcaatgttct caatgtttgg acaaacccca caaggactat aaaaaaaaca agtaggagga
    10921 gtaaaaagta cgtggctact ttttactcct ttttttatga aaggagaata ttcatgtttt
    10981 ttacgatttc aggaaatgca aaattggata aagagttaat aagaaaagca acgaagaaag
    11041 tgggaaagcg tacttccttt ttaccgaaaa caattaaata ttctgtcatt gaaacggaag
    11101 aacagctaca tgtgttagga caagtgttag aacaagagaa tcaatcttct gttaaattga
    11161 ctctcacgtt acatgataaa gaaggaaaaa tagaaaaggc tggcacagaa tacgtttttg
    11221 gcccactgga ttatcaaatt tcagaaggtt tttatcctac attgatagat ttaatccgcc
    11281 ttgatgtgtt taaagatacg gatgaaacta tgagtgtgga agagtcttat cgaaacgaaa
    11341 aacttttaca agttttagaa gaagagttag agagcgacca aagaaaagtg aatcaagtga
    11401 gtgaagtcga agtaaatgaa gaagtaccat gggaacgacc aatctttcca aagaaggagt
    11461 caaaagaaaa agagacagtc tatgttgacg aacaagctga tattccgact cagaaatcga
    11521 tatttgagga agagaacgat gtgatgggtc aattggaggt agatcccttt gaagaaacaa
    11581 tggaggatga agagacggac gaagtagaag ttgatccagt tgaagctaat gaagagtcaa
    11641 catggactga aggggatttt caggaatata ttgaaccact tatcagtgaa gaagtagaaa
    11701 aaaacgaaac agagatacaa aaggcaactg tatttgatta tattttggat caatatccgc
    11761 cagagcatga atggatgaaa gaaaaaaaca aattattttt aaatgagctt tattcgaaat
    11821 atcaattacc ccaaacctat caagcatttt tagagagtaa agaagaatta atctcacagg
    11881 gtaaaggcac acttttagaa cagttagagt ctgtccaatc aacaaattgg catgagcttg
    11941 cacaagaaga tttattagcc acctttgaag aacgtcaaca agaaacagat caagaaatta
    12001 atgagtatgc gacggaacag tcgtctaatt gggagaaagt aaaagaggaa ctaaataaag
    12061 aagaacagcg agtgattgaa gaagaagtac aaaaagtcaa agagcggtac gaaaagaaac
    12121 gcgacaatgc ttattccttg tgtgtagaaa agatcaacaa ttttactaag acgaatcaag
    12181 aagcgttatc gaaagaaaaa gaaaacttgt taaaagaacg tattaaagaa cgaaaagaag
    12241 agttctaccg cggtttacgt acagataagc taaagattag caaagaatta aatgaacaac
    12301 tgaataagct atatcaaaca acgactgaag ttcttatgga aaaacacgaa cagatccagc
    12361 aagaattaca agtacaaatt ccaaaatgga aaaaagagta tgaaattcaa caacaagaat
    12421 tgaaagaaca agaagaaaaa caacggcaaa aagaaaaaga gcgtgaacaa ttagaaataa
    12481 gaaaacggga acaggatctt gcggaacaaa aaatggcgat agaaaaacaa cggttagagc
    12541 aagaaaagga aaaagaagca gctgctcgta aggaacgtca agaacaaatg gatacattgc
    12601 gtcaagcaca gttgaattat ctagcacaac ctcaaccagt agctgctgtt caaacgccag
    12661 tgaacaacca agcaaattta actccttcac cccagcgttc ctttaacgga tggatggtgg
    12721 gatgtattgc aagtttaagc ttgcttctag gtggaggaac agtatttgct tttaatcata
    12781 tcaatcaatc ttcacaggct gattctgtag ccacaacggc gtcaatcaag gaagaagccc
    12841 aggaacaagc aagaaaagag tatgaacaac aattagaaga attattgaat cgtaccaatc
    12901 agtcaacaac agagtcaagc atggaaaata gcaaagagag tgattctagt aaggctaaag
    12961 aaggatcaag cgattcaact gtacaatcaa acacttccga aagttcagaa tcaaatgagg
    13021 tgaaataatg cgtgttagag aaacaacgaa gcgaaaagac aaacgattca atttagaaaa
    13081 gaataggtat ctttctcatt tctatcgcta tactccctca ggagaagagc taccagaaaa
    13141 acatgacaaa cgcatttcga aaaagatttt ttatagtgga cttgtatacc tccctttaga
    13201 gtatttagta acaagagtac cagaagtttt caaccgattg gaaattgtta agggaagctt
    13261 acaaggaata aatctgtttc aattacagga aatgccacag gtctttcatt ttgattcagc
    13321 tggtttttgg aatccattta ctcctacaac tagtttgggt acacgtttag caatttcgac
    13381 agtttgtgtg gttccagctg tacttatggg attgaaaatg gacatgtggt ttcgtcctct
    13441 agcagatgga caaaaagggg ataatcgatt aatgacctta aaagaaatcc aacagattta
    13501 tccgcaaata cctgaaacaa aaactacttt tccaggttat ggaggtattc caatcacaca
    13561 ttacaaaaaa tattggtaca ttcaaacaga tactgttaat acgtgtattg ttggtacctc
    13621 tcgatcaggg aaaggtcaga ttgaagtgtt agccaccatt gacaatttat ctcgtgcaga
    13681 aaaacaaagt tcaatggtcg ttaatgatcc aaaaacagaa ttatatgttg gtagtaaaga
    13741 tgaactagaa gctagagggt atgatgtata tgcctttaat atcaccgatc cactgcaatc
    13801 aatgagtgat aatccattgg cactcattgt gaaatactgg aagcgaggag acatagacac
    13861 cgcaacacag ttaaccaata cttttacgaa tacgatttat tatgatgcaa atgcttcaga
    13921 caataaatac tttaacgaaa atgcgcagaa agctgtcaat gcgcttattt ttgcgttatt
    13981 ggaacaagcg gatcaaacag gggattactc caaattaaca ccaaataatc tcgttgaact
    14041 actttcagaa attggcggtt ttaattatta tccagatcct gagaatgaat tcaagcagct
    14101 caatgcctta gatgagttca tgaatcagtt accccctgga aatatagcaa aaaaacaata
    14161 tggggcaaca aaaattggat ctgataaagc gaaagggaat atcttgtcta cggcaattac
    14221 aggattgaat ccatttaccc taacgaaaat tgcgaagatg acttctcaat cgaccattga
    14281 ttacaagtcc attggttttc cgaagtattt ggatctcaaa ttacatgaaa gcctattaaa
    14341 tcaacgcatt gtcgtggaat tttatcataa gggaaagaaa tttcacgagg aacgagtcaa
    14401 agttggctat cgtggttttt gtgaaatcaa ctttgattgt catttagagc agggagatca
    14461 tgtttgctta aaatacaatc atcaaggaaa acaatatgtt gcttggtatg agttttctca
    14521 aaaagtattg aaagacgaag agggaaaaat cgtttatcga aaaaaacgag gagaaactca
    14581 tttgccagaa ctagaaaaag aagccgttct aacattagat gagaagaaaa gtaacctatt
    14641 agtagagtct attcggatgc actataccga taaaccaatg gctattttta tgttaacgcc
    14701 tgattatgat ccatctaacc atatcattgt tagcatcttt cttagtcagt tgtataaaga
    14761 attatctacg caatgtgtta agactaaagg agataaatgt caccgtagga ttcattttat
    14821 tttagatgaa tttggaaata tgccaccgat ggacaacatg gaaggaatca tgacggttac
    14881 ggcaggtcgt aatatgttat gggatctgtt tattcaatct tatcagcaac tttatgcgaa
    14941 gtatggagaa caaaacgcag cgattatcaa agaaaattgt cagacacata tttatattat
    15001 gtcgacagat gataatacca tcgaagaatt ttctaaaaaa gtggggaata agacggttga
    15061 acaagagaac agtaccatca attcattagg tatgaatact catatcaatc gcaatgttga
    15121 ttcagatcgt atcttaactc ctgaaagaat ttctactttt ttagaaggtg aaacgattgt
    15181 actcgctcct ttaaaacgac aagatttgaa aggtcataaa atacggccgt atcctatttt
    15241 taatcatggg gaaacgaatc ttccttatgc ttatcaatat attgaagatt tcaatccatc
    15301 gtgggatatc aatgatatag acatacattg tacacatgcg gacttggatc ttaaggcttt
    15361 acaaattgat tatgattatt tcctaccaga tgaatatgct agaaatctct atcatggact
    15421 gcatgatcaa ttagaagaaa aaaacgaaga aaatatgttt tataaaatcg ttcaatcttt
    15481 tgagaatgag acggctaaaa aattgttaat tcaattttac gaagaacaag caacggatcg
    15541 tcttcaagaa tatgttgaaa agttgatcaa aaatgaagaa atttctgaaa tgattaggaa
    15601 acggctgtta ttggaagctg aaaaggcggt gaaagaatga tcattggagg aattttctct
    15661 ggcatagccg actggtggtc aggtttattc ggagaagggg atgcagatcc caaaaccgta
    15721 acgaaagtct tacaagatta tggtaattat ctgcagtatc aagatgtatt cagttggatt
    15781 tgtaatactt ttttatgggg attgatcaaa gggttatata atctcaatac tttattagaa
    15841 aaaacaattt atcaaagctt tgatttaaaa gacttattga acgccgctgg tgttaatgaa
    15901 ctatttcaaa gtttgattag taaggtattg gctctttttt gtgtcgtcac attaatttat
    15961 ttaggcttga aattttttat gagtaaacac ccaccgaaag tcaaaaatat cttggttaat
    16021 ttatttatgg ccatgatctt gatttttggt ggtagttctt taatcgatga agggttaaat
    16081 atcagtaaaa acttttatgg agacgtcact gcagcaaata aagcagataa aacgggttca
    16141 cctgcttttc aaattattca aaataatgtg attgatgtca gtacattact agcgactgac
    16201 ccgaataaag tagaatcctt accaacagat aaaagaaatg ctttaacagc gaaaaatttc
    16261 aaaacagcga atatcaatgg gattattaca cctgatcaag ctaagaaaat gtctgaatca
    16321 agtgatatta gtacagtaca aaaagatcgg ttaaaggcat tacagtatcg actagagtta
    16381 gacgataatg ggaaagaaat ccctgttcaa attagtgatg aaggtttagc aaaatatgtg
    16441 tatacgtcag gctatcgtcg atacattagt agtccaggga ttattttggc tggggaatct
    16501 tctttgtcgg tagcctattt atttattttg tttacaatcg ttacttgcat tattgagcta
    16561 gtatttaaaa aattctattt agtaattgcc gcgtcaacgg actttgagac aggacaacgg
    16621 atgaaaagtg cgatagaaga tatttctcaa tccttcttgt tattggcgtt tacgatttta
    16681 gaattacgaa tctatacatt aatgctttca ggtatcggtg atttgcatgc ggtaggaaag
    16741 atcaatggat tcttgtatgt tgttgcttta attgtgctaa ctattgcgct attcaaaggc
    16801 tctcaatcgg ttacgaagat tttcggtgtt gatacgagtc tgaaaaacgg cagcaattct
    16861 cttcttagca tgtttgcctt aggaaatatt gcgaaaaatg tgggtagcgg agctaaaaac
    16921 cttgcaagtg ctggtaagag tggtttaagc catttaaatg atattcgtaa gaatggattt
    16981 ggccatcgaa aagatattac ccatgataac ggggaagaac aatcagacga taaagctaca
    17041 actgtaccta atagtaagaa gacagtttcc gaaatgttcg ggaaagcgaa aaatggtgtt
    17101 tctaaagccg cagaaggtct tggttacgtc aatgaacgtg ggttaaaagg aacagttgaa
    17161 gatcttacag aaaaagccaa agacacctta gaagagaaat tagacggcac gagagctaaa
    17221 gaatttgctg aagctgtgaa gaatccatcc gaagcactag aaaaacaaaa agaaaaagct
    17281 tcagcagtca aagaaggact aaaagatgcg tatggtgaag gacaagtcaa tgcagcagtg
    17341 aaggcaaata caacaagtga aaaagaaaat caagaaggtg cagcgattcc ttcagccaaa
    17401 gatcaccaag atgagttaca ttctaacgaa aattcgatcg gagaaaaaga ttcagaagaa
    17461 ggacaacatg gtcagttacc aaaaaccgat ccagaacaat atcgttataa atctaacatt
    17521 aattctgaaa acgaaaaacg catttcagat ttaccaaaac gaaatcaaga agtacaaacg
    17581 gatgaggatt ccatcgatct gccaaatgat aatggcatcg aagttggaac tgaaaaatca
    17641 acgaaaattg gtttgcctaa gacacaaaat ttaccaatga aagatagtcg tttgaatcaa
    17701 ttcaaagaga atgatcaaag ctttgttcat caatcacctg caggtactgt tcaaatgaaa
    17761 tcaagtcgtt tgcctgaaaa tggaaatctg acaactgttt cttacaattt agctgaaagt
    17821 ggtgaaacag agaatgcgtc cgttcaaaat attgtgacaa aagaagctgc acctaagcca
    17881 atcaataaag ttcataatgg atacagacca gcaaacgtag catttactgc accgacaaaa
    17941 ataaatgtga caagagaaac taaaaacagg aacaatgaat tgaaagaaca actattgaag
    18001 gatatcaaac cataaaaggc ctatttaagg gcctttttct ttataaaaca agtttaaaat
    18061 ggaaaggaga aaattgtgga ggatatttta atagctacgt ttataactgc actgggagca
    18121 tttttaacga tatttgtggt gactattaaa ggatttaaag atacggatag tttacaaaaa
    18181 gatcatcagt ctattttaga tggtcaaaaa acacataccg aaagcattat tgtacacctt
    18241 tcagaaggat tcacttattt gaaagatgct atgcccacat tcacagtaaa attaacggaa
    18301 atatttcatt ctgttgagca aatatcgtca gaattgaaag agcaaagaca acaaaaagat
    18361 cgtcaacttg gctcacttaa ttttaggcaa gaaacgatac aagaatcatt ggagaatgta
    18421 aatcgattaa acgatgaaat gcaacgagtt catttggaaa atgaagaatt acgcgcacaa
    18481 aattatgatt taattcaaaa gaaaagaaat ctggaacaaa aaattgttga attaaaagaa
    18541 gaaaatcgtc aattgaatta tcaattacga cgaggaaaaa atcgttctcg tgatttagga
    18601 aatgaattag agttgtaata tttagaaaaa cgctgtgaga aatcacagtg ttttttattt
    18661 ctaaaaatac aaaatataag gggtatggtt atattatgga taaatacatt catatgaaaa
    18721 atcctccaag atttagtggg gaatggaagt ttttcgcctt tttcttttta gatctattaa
    18781 cgcttggtgg ctgctttttt tgggcgaaaa tagtcaataa tcttgtccac ttaccactct
    18841 tttttgcact cttgaattat ggattatggc ttgcgatagc gttagtgatt gtttggcgac
    18901 cctataataa ccctggtcaa cgccaaattt ttgcgattat cgaatctatt ttctttacgg
    18961 ataagaacca ctatcatgcg ttagatccta accgaaatta tcatggtacg tataaggagg
    19021 atgaataaat gcgagtcaaa ggacaaaatt cagttgataa gaaatccatt ttgcagtttg
    19081 gaaaaccaga agagcgctct atcttggact tatttccata taaatcctgt acagaagagg
    19141 gagtcttaat tactagagaa gatcattttc agcgttatta tcgtgtcgtt tccactgacg
    19201 tggagggatt aaatgaacaa gagaaactag aacgaatgaa tcagttgacc accgtcatgc
    19261 gtacgtatgt gccaacaatt aagttagtta gtttgaccac agagacggat ctaacggaac
    19321 aaatcgtgca aaagcggcag ttattagata aaaatcgtat ggaacagtca ctaggaagaa
    19381 atctacagcg attaagaaaa tatgaaaaga aattagtaga ggagatccag gaattaaaac
    19441 gggcagaaca agaacgtcct gacttaagct tctttttcgt tattgaagga aagacaatca
    19501 aggatttaca aactagaaat cgtcagttaa tgcgatctag tggcatttta gggttaaaac
    19561 cactctacaa aaaagaattg attaagattc tttatcgaat gaacaacatg aatgacgaat
    19621 aaaaaagatg gaggaaatga ttcatgctag atgtgataaa aacagctttt tcaacgcaaa
    19681 gtaatcaaaa ggtgattgat ccattaaaac aacttggtaa tcgtgaaata gagattttaa
    19741 aatcaaaagg ttatgattta gatttcttaa aacaagtgat gccacaaggt gggttgaatt
    19801 ttgatgaaga atatgtgacc tatggaaatg gttattcacg atgtgtgaca gtttatcatt
    19861 acacaaaaaa tcctactctt ttttggttgg ccaatctcat gaacaatcct catacagtgg
    19921 ccacactaga tgttagcaca gatgaaaagc aaaaagtgat tgatcaaatc aaccgcgcat
    19981 tagatgaatt aaatgatcga tcagataatg aacgaaaagc gactgaccga aataaaagtg
    20041 cggaagaata cctggaacta gcggaatatg cccgaaaatt gacttctaat ggggaaattt
    20101 ctaaacaagt caaagtgaga gtacatgttt acggaaatac gatccaagaa gtggatgaac
    20161 gggcgcagga actgatcgaa aatctaaaag ggatggatta tcgtgcggtg acttatctgc
    20221 ataaaaccaa acgagattgg caatcgatgt ttaccatgtt cgatgaacaa gctgaatggt
    20281 ttggaaatat caaagggcaa tcacttccat cgttaaacat tggcggagga ttcccgttcc
    20341 accaccaaac gctaaaagat ccaggaggca cacaatatgg ggaaaccatg acaggcggcc
    20401 catttgtctg gaatgccacg tataaaaata gtgtacgttt atctaccaat accttgcttc
    20461 taggaatgat gggagctggt aaatcgaccg ttcttaaaat gatcgcggaa gcccatttag
    20521 ctgcaggaga ctttatttgg ggctttgaaa agggaaaaga ctttattcct ttcttaaagg
    20581 aatataacgg tattatggtg cgtttagacg gatctgacgg aatgatcaat cctttagaga
    20641 tatttgccac acggacgtat gatgaagcat ccagtttata tgacgatgga tcagtcaaag
    20701 atttgaagat caatgaagca gcgtcctatc aaacacactt agacaaagtg gtctatcagg
    20761 tacagttagt gagtcctcag ctaaaaggaa cgatgaaagc agaatttaag acctacttaa
    20821 atcgttttta tgaagagtat ggaacagtac cacgcggctt tacttcctca aattcgcgtt
    20881 caaatactga tacgcaagtc acagggaaag atccagaagc ttatccgacg ttcaaagaat
    20941 ttttagcctt tttaggacaa ctggaactac caggggcttc ccaagagaaa aagaatcgga
    21001 aagaagaaat ggagtctatc gtggaatcct tatgtgagac ttatggcatg atttttgatg
    21061 gtcatagtac gattcgacac cttgaccaac aacagttggt cttttttgac attgactcta
    21121 ttacaggcct agatcgaggg gtacaacaat gtcagatgta catggccatg acgttgattt
    21181 ggaatcaggc attgattcaa ggacgaagac aacgacgctt aattaaagaa aaacaaatgg
    21241 aagaacaaga cttcaaacgc ttcttggcga tgattgatga gtgccataat ggtgcgacct
    21301 gttctgcagt gaaaagctgt gggttgcaag tagtctaaaa actattgtaa taactcttat
    21361 aacgagaagt caaatgagtg ggtaacgcca caaagggctt ccactgatac tccgacatgc
    21421 aacaagtagt ttatgcagac caacgttgtg tgaagctcgg tgaagtcggc tgaaggatac
    21481 cgtaaggtaa aagaaatagt gaataccacg aaagttctct agaggtaaag ggtgtatccg
    21541 ataagtcggg tgtccaaaaa aacttaatat ggtgagtatg tacaaacgta ctgacgaact
    21601 agcgaatgta ctgtccgaaa ggcatagctc ctagaaatgg gagagacagt gagcaaaaaa
    21661 tcactcattg tgctaacttg tggttgagta aaagtcgttg ttatgaaaga ccatgctgcg
    21721 ttacaggcgt aggagaagtt agggggcaaa agctagcatc taagttaagg catgtggata
    21781 gatataaggg aacaggggaa gccatcaaca tggagagtgc atactcgatg aagtggtagt
    21841 aagaaatatg tgaatgacaa ataacttact ttagtgatgg tgaaagtaga gtcacgactg
    21901 atgaaggttc tgtaatggaa ctggaggaac aggctcgatt cgtctgtaaa agtcatgaaa
    21961 cccgttcaac catgggattc tcgtatgact aaaaaggtca cgagccaatt ggagcgtgat
    22021 aaaccatgac aaaagaaaca agtccaaaag ataggaagtt gcggcatgca gaatattatg
    22081 gcatgacgga aatcttcgat aagatatact ccaaaagttt gaagggagat aatttcaaga
    22141 atctaatgca gattatcatt tctgataaca acattgtcct agcatatcgt aatatcaaga
    22201 gaaatcacgg tagtgtgaca agaggagaag atggagtaac gattaaagat attgaaaatc
    22261 tcaaccgtaa tgaattcgta gaaattgtta ggaagcgatt cgcacattat aaccctcgga
    22321 aagtaaggcg tgtagaaatt cctaaatata atggtaaatt aagaccgttg ggtattccat
    22381 caatatggga tagaatcgcg cagcaatgca tcttacaagt attagaacca atatgtgaag
    22441 caaaattcaa taatcacagc tatggtttcc gcccaaatag atcagcagaa cacgcaatag
    22501 cagattgtat ggcccgaatg aatcaaagtc acatggaata tgtggtagat gtagatatca
    22561 aaggtttctt cgacgaagtc aatcatacta aactcatgag acaaatctgg tctatgggta
    22621 tacgagacaa acagcttctc ttaatcatta ggaaaatgtt aagagcaccc gtagtacttc
    22681 caaatgggaa gttgatatac ccaacaaaag gaacaccaca aggcggaata cttagcccat
    22741 tacttgcgaa catcaatctc aacgaatttg actggtggat agcaaatcag tgggaggaaa
    22801 aagatgccaa agagctaaaa catcatttta ggaaaaatgg agcttgggat aaaggtaata
    22861 tctatcacaa gctcagaaag agtacaactc taaaagaaat atacctagtg agatacgcag
    22921 atgattttaa aattttctgt agaaattata atgaagcgaa aaaagttttc tatgcaacta
    22981 aaatgtggtt acaggagcgt ctaaagttac caatatctga agaaaagtca aaaatcacaa
    23041 atctttcaaa agaagaaagt gaatttttag gctttacgat gaaattagtg accaaaggta
    23101 acaaaaaggt tgttaatacg catataggta caaaagcaca aagcatgatt aaagtgaaac
    23161 taaaaaaaca aatcaaacga attcaaaaaa gtcctaatag caaagatacc tttatctata
    23221 ttggagtcta taacagtatg gttattggga ttcataatta cttcaaaatt gcgactcatt
    23281 gtagtgtagc aatgcgaaaa attgcaagag aactcagacc aagttttgaa atacgactac
    23341 gagaacaagg aatctcaaaa gaaggacaat acggaaagta cgaaggatac aagccttacc
    23401 tacggtcagg acaaatacga tatataagag ggtttccaat attaccagta gggtatattc
    23461 aacacagaca tccgatgtgt aaaaaaagaa atattaataa atacaccgaa gaaggtaggg
    23521 aagccattca taagaagcaa caaaccgtag aagaatggaa gatatcgtgg ttgtgtagca
    23581 atccagtgct tagtaagaga gcaacgattg aatttgcgga caatcgaatt tcaaaattca
    23641 tcgctcaaaa gggaagatgt gcagtaacag gtgaggagct tatcttatct gaaatgcatt
    23701 gtcatcatat tatcccttat catgaaagca aaagtgatag ctatgaaaac ctagtgattg
    23761 ttactgagga ggttcatcgg gtaatacacg ctacacaaag tgaaacgatt gaggaacttc
    23821 taaaatatct aaaattaaat ccaaaacaaa aagaaaaact caatgagttg agattaaaag
    23881 ttggtaacga agaaatatct taataaatat ttgtaggacg ggaaaacaga atgtctttta
    23941 tagacgaggg aacgccgtat gcggtgaaag tcgcacgtac ggtgtggact gggggaaaag
    24001 acggagataa tatcaaactc ttacctatca gtatcgatta atccagattt tattgaaacg
    24061 gtaaattatg tcacaaactt tcaacgagaa atgcgtaaag tagaagcaat gactgtttta
    24121 gctacacaat ccccacaaga aatggtgcca gaaaatatgt cttctgataa cttctcgaaa
    24181 ctgaagaaag tctttgaatt ttcttctacg aagatcttta tgcgtatgga tgaatctatt
    24241 ttacgtcata tagaaggatt agtgggtaaa tcaatgacga actcagaatt agaatccatt
    24301 cctcaacaaa atcaaggaga cgctgtgatc aattttggct caaaagaaac cattcgtgtt
    24361 cattttagtc cgaacaaacg tcaattaaaa ttgtttgatg gaggaaaata atggaaaacc
    24421 aaaatgaaag tttaatcaag cagtatgtta agcgtcgtgc aaagcggcgc ttatttttgt
    24481 ggttgtttgg tacttctgca ggtttgatta ctattttgat cactgtgttc gtgaccctat
    24541 ttctaatact tgcggcgggc tcgattgata attcggattc agattcaagc agtggtggcg
    24601 aagcttttac aggagaatat tcggaaggct taccgattta taaagaaatc aaaggaagag
    24661 gccctttttc tgatgagatt gcgcaatatg ccgtaggtgc agcagtgaaa tataaattat
    24721 taccaagtgt gatcctttcg caatacggtt acgaatcagc gtttggtaca tcggcgtccg
    24781 caagaaatga tctcaactat tttgggatta cttggtttga tggttgtctg tttcctaaag
    24841 gaactgcacg aggaattggt ggcattgaag gtggctggta catgaagttt cccaactcaa
    24901 aagctgcatt ttcctattac ggctttatgg tagccacaca atccaatttt aatgcttgtg
    24961 taggaaataa aagccctggc gcaagcttat tgatcttagg acgaggcggt tatgccgctg
    25021 caggaattac ggaagatagt ccgtattata caggttgtat gtcaattatc acttctaata
    25081 aattaaccga atatgatgaa ttcgccatca aacattgggg tgaaggtggc aataacaacg
    25141 gcacgattac tggtgaatgg acgaatccat tccctggcag cagtttagat aaaagttcct
    25201 tcagcggtgg tcaattattt ggaacgaatc caggcggtga attccgtccg aacggcttcc
    25261 atgatggatt agattttggt tcagttgatc atccaggaag tgagattcat gcggttcatg
    25321 gcggaaaagt cgtgtacgtt ggcaatcctg gtatttcagg tttgggcgcg tgtgtgatcg
    25381 tgattaatta cgatggcttg aatatggtgt atcaagaatt tgcaaatagt acaggaaatt
    25441 ctcgagtgaa agtaggcgat caagtgaaag ttggtcaagt aattgggata cgagatacag
    25501 cacacttgca tttaggattt actcgaatgg attggcgtca agcacaagga catgcattca
    25561 ttgatgatgg tacatggatc gatccgttac catttttgaa tagcagtaaa aaatagatca
    25621 ggagaaaaaa tatggaaaat aaaacgttaa aaatcgtctt aacagctgca attagcgtta
    25681 gtttaatcgg caatattgcg ttgttttggc agctgaaaga ggaacaagca gcaaatacct
    25741 ataaaattga agaagtggct aaaaacgcgt ctgagaagct caaaaaaaat tcctctgagg
    25801 cacaggcgaa gatcgacaag ttaaatcaaa ccatcaatga gaaaaaccaa gaaatcgatc
    25861 agctgaagca acaagatggc acaaaagcaa aagaggaagt aactgaagca caaagaaaga
    25921 cggcagaaga gttcggtcaa ttggccattg ataaatcatt aagcagaaat gaattaacgg
    25981 aaaaactaaa agatgtcgca acccaagaag tgatcgacaa attaagtcct acagacgatg
    26041 atcaccaaca tgatgattac ggaagttact cctttacatt aggtgacgtg caaacttacg
    26101 ctcaaacaag cagtgtaaaa gaggaacaaa attttgtcgt atttgttgat tatacaatcg
    26161 gcaatccgca attcaaagat gtcaaaccac aaaaaataaa aggtggatta actgtcactg
    26221 aaaaacaagt agatggtcaa tggaaagtca tagactttag ttatttcact cgttaggagg
    26281 aagaaaatga gtaagaaaaa aggagaaaga caacgtttca aaaaacgaaa aagttatctt
    26341 agatggctgg gaatctttat gattctcggc tttttgattc ttgctagtcc gatttatacg
    26401 aatcagaagg tagatatacc agatgaggta agcacgaacg cctttttaaa cacgaaagag
    26461 ctgacaatgg tttcaaaaga aaaaggagcg aaccagcaat tagtttttga atttgcgatc
    26521 gatgatgaag atcaaagctt gttaaaagaa ctggctaatc ttaattatcg cgtagaagta
    26581 aagacagcta aaggggatta tcaagcaata cgagccaaag tgattaaggt gtctgatgat
    26641 tattttgcag tgaagctaac gcatgtacca gaagaatata tcgccatgcg tttaaccatt
    26701 attcctgaaa aaattgatcc aaaagtggat atgcaagaac cacaagatct gatttattac
    26761 gtgcacgaag ataaggttaa agatcaagtg aaagatgaag attatgaaca acacgcgatc
    26821 aattacaaag tgaaaggata caagaaagaa caaaaagcag ctcaaaaaca aatggaatct
    26881 ttccaagcaa ccattgattt gaatgaagaa ttagtgaaga agctaaaaga tcaattgcct
    26941 tatcaagtcg cagatgatca ggaaaatact gaaaacaaga ttaatagcta ccagcaagaa
    27001 attgaaacat cgaaaacgca actgaaagat caagaagaga tcattcaaaa acttcaagaa
    27061 aaaattgatc gtatgacaaa agaaaagatt tagaaggaca ggtggagtga aaaaatgaag
    27121 cgaacaaact tggctgacaa agatactttc gctgagcaga aagtattgat taaagcctat
    27181 ctcaaagttg taaaagctaa agaaatatgt cgagaagtga atttatctaa cacaacaata
    27241 tctgagttga agaatggtcg aaagaattta gatactttaa aattcagatc atttgaagct
    27301 ctatatgtag ctgctaaaaa atattttaca gctgataaca aataaaaaac aggagtattt
    27361 tatgtgaaaa aagtatataa aaaatgctta tgaatcagct atatcacctt aaccatttgt
    27421 taatgagatg ggagaaaaca ttaaccacga ttctaacgca aacatcaagc acataaaaca
    27481 tttaacactc ctcctttctg gctgaagatt tcaaccaaac aggaagacag cgtatcaatt
    27541 atagcataca ctttttctta aattcatttt tcatatgaca aaatatttcc ttctaatcga
    27601 caaagttaga aggatttttt attgtctaaa tacacaaata accttaattt ttaaagagca
    27661 taaggaaacg tgatatcact ttctcacgaa aggtgttagg taggctgtgc ctaccacgtt
    27721 tctaagaaag ataaatgata tcaaaatttt ggatttgtgt gtagatttgt gggtaggatg
    27781 aaagcgaatg tgggcagtaa aataagcgtt tgtgtgtagc aaaatcaaaa aatgtgtagg
    27841 gatatgtgta gctacacata tccctacaca taataaattt ggaggaaaat atggacttat
    27901 taattagaaa tattgaagaa aagtatatta ataaaattga caaacgttgt gaagaactta
    27961 cggtcaagac tggcaaaaaa tggagtcgaa atcaatacct aaaagttttg atcgaaaatg
    28021 attttgatca cgctcttctg aattataaaa aagaccaatt tgatcggttg ttagaaaaat
    28081 ttgtggatat tcaaacttat aatacgaaaa ctttagaaga atatattgca acaaataatc
    28141 aattaattgg tttgttaatt gaataataaa aatagtattg tgaatttata aaaggaggaa
    28201 atcaattttg gcaaaagcaa caagaaaaca tgtatatctt tacgatatgc atatcgaagt
    28261 acttgatgaa ataatttcta ctcatgaaga tatatctaat tatagtgaag cagtcagaca
    28321 tttgtgtatg atgtatgatc caaaaatcga agaaaaaata aatccaattc aaattaaatt
    28381 gaatgcaatg ggaaaagaaa tttctatttt aaccgaaatg gtttcagagt ttgcggatct
    28441 tcatttgaaa gatacaggaa tactaattgg tacaaattca actgtttatc aagaagcaga
    28501 agaacgtgtg gaaggaaaaa ttaaatccaa tcaaaccaaa aaatattctt ctaagttaaa
    28561 gaaaccagtg aatgaatctg ttcataccag agtagatcca tttgatccaa cgaagattct
    28621 aaaaagataa aagtagaagg agaacgtgat gaataaatcg cctgcagtta ttcttacttg
    28681 tcaatttacc ttgcccaata aaaaatcttt ttcaacatac attgattata tgacaagaga
    28741 aaaagcactg gaagaaatgg aacgacgtac gcccgaagaa gaacaggaac tgcaacgaat
    28801 caagaatgct ttagaggatt tttatattcc tgaaggagaa actttttcgg aaagtaagac
    28861 gg
//
LOCUS       DAYNVV010000032        28688 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.032, whole genome shotgun sequence.
ACCESSION   DAYNVV010000032 DAYNVV010000000
VERSION     DAYNVV010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28688
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.032"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(27..1193)
                     /locus_tag="ACGXWR_001595"
     CDS             complement(27..1193)
                     /locus_tag="ACGXWR_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFK0803168.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(1205..1558)
                     /locus_tag="ACGXWR_001596"
     CDS             complement(1205..1558)
                     /locus_tag="ACGXWR_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFK0803169.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            1686..2708
                     /locus_tag="ACGXWR_001597"
     CDS             1686..2708
                     /locus_tag="ACGXWR_001597"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HFK0803170.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            2727..2888
                     /locus_tag="ACGXWR_001598"
     CDS             2727..2888
                     /locus_tag="ACGXWR_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803171.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(3147..3581)
                     /locus_tag="ACGXWR_001599"
     CDS             complement(3147..3581)
                     /locus_tag="ACGXWR_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803172.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(3691..5550)
                     /locus_tag="ACGXWR_001600"
     CDS             complement(3691..5550)
                     /locus_tag="ACGXWR_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFK0803173.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            5551..5691
                     /locus_tag="ACGXWR_001601"
     CDS             5551..5691
                     /locus_tag="ACGXWR_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoglycerate dehydrogenase"
                     /protein_id="HFK0803174.1"
                     /translation="MLAPSFLSIKECCFSYFSCTKFESKERKEELMKSKYSLSLWPFW
                     FL"
     gene            complement(5668..6827)
                     /locus_tag="ACGXWR_001602"
                     /pseudo
     CDS             complement(5668..6827)
                     /locus_tag="ACGXWR_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
     gene            complement(7134..8558)
                     /gene="araA"
                     /locus_tag="ACGXWR_001603"
     CDS             complement(7134..8558)
                     /gene="araA"
                     /locus_tag="ACGXWR_001603"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008733 - L-arabinose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HFK0803175.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(8574..9272)
                     /locus_tag="ACGXWR_001604"
     CDS             complement(8574..9272)
                     /locus_tag="ACGXWR_001604"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFK0803176.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(9229..10890)
                     /locus_tag="ACGXWR_001605"
     CDS             complement(9229..10890)
                     /locus_tag="ACGXWR_001605"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0005998 - xylulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HFK0803177.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            11108..12508
                     /locus_tag="ACGXWR_001606"
     CDS             11108..12508
                     /locus_tag="ACGXWR_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HFK0803178.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(12760..13839)
                     /locus_tag="ACGXWR_001607"
     CDS             complement(12760..13839)
                     /locus_tag="ACGXWR_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFK0803179.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(13925..14884)
                     /locus_tag="ACGXWR_001608"
     CDS             complement(13925..14884)
                     /locus_tag="ACGXWR_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HFK0803180.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDTLIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(14896..16407)
                     /locus_tag="ACGXWR_001609"
     CDS             complement(14896..16407)
                     /locus_tag="ACGXWR_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA];
                     GO_process: GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-arabinofuranosidase C-terminal
                     domain-containing protein"
                     /protein_id="HFK0803181.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(16429..16992)
                     /locus_tag="ACGXWR_001610"
     CDS             complement(16429..16992)
                     /locus_tag="ACGXWR_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFK0803182.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(16998..17861)
                     /locus_tag="ACGXWR_001611"
     CDS             complement(16998..17861)
                     /locus_tag="ACGXWR_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0803183.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(17875..18771)
                     /locus_tag="ACGXWR_001612"
     CDS             complement(17875..18771)
                     /locus_tag="ACGXWR_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0803184.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(18946..20235)
                     /locus_tag="ACGXWR_001613"
     CDS             complement(18946..20235)
                     /locus_tag="ACGXWR_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFK0803185.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(20207..21724)
                     /locus_tag="ACGXWR_001614"
     CDS             complement(20207..21724)
                     /locus_tag="ACGXWR_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HFK0803186.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            21922..22812
                     /locus_tag="ACGXWR_001615"
     CDS             21922..22812
                     /locus_tag="ACGXWR_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HFK0803187.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(22885..23709)
                     /gene="nadE"
                     /locus_tag="ACGXWR_001616"
     CDS             complement(22885..23709)
                     /gene="nadE"
                     /locus_tag="ACGXWR_001616"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HFK0803188.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(23721..25193)
                     /locus_tag="ACGXWR_001617"
     CDS             complement(23721..25193)
                     /locus_tag="ACGXWR_001617"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HFK0803189.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(25830..26192)
                     /locus_tag="ACGXWR_001618"
     CDS             complement(25830..26192)
                     /locus_tag="ACGXWR_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFK0803190.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            26415..27167
                     /locus_tag="ACGXWR_001619"
     CDS             26415..27167
                     /locus_tag="ACGXWR_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFK0803191.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(27307..28230)
                     /locus_tag="ACGXWR_001620"
     CDS             complement(27307..28230)
                     /locus_tag="ACGXWR_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFK0803192.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(28245..28517)
                     /locus_tag="ACGXWR_001621"
     CDS             complement(28245..28517)
                     /locus_tag="ACGXWR_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803193.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT         8479 a         5987 c         4885 g         9337 t
ORIGIN      
        1 gatattttcc catctgtctc tttttgttat tctttctgct ttttcaacgg attttcttca
       61 taaagagaag agattgttgt gtaccattca aaaacatgag taatcactac tttagctgct
      121 gcataaacag gaatccccaa gatcacaccg atgattccga acaatttccc agaagtcagc
      181 agaactaata aaatcgttac tggatggatt gctaactgat tccctagtac taatggagag
      241 atcaagcgtc cttctattgt ctgctctact gcaaaaacga tcagtacttt gatgatcatg
      301 aatggacctg ctacaatggc taaaaagata gccggaatca tcgctaaaaa tgatcctaag
      361 taagggatca ggtttaaaaa acccgcaata atccccaacg tgacagcata ctctaaacca
      421 atgaccgcaa aaccaatcat aaacatgatt gccacagcaa aagccacagt tagttgtcct
      481 cttatataag aagaaacttg actattcatt tcactcagca cattcaacgt cggtttttgc
      541 atgcgtgtcg gtaaaaattt gacaaaataa ggtgctaatt gtttaccgtc tttcaataga
      601 taaaataaga taaacggcat cgtcagcaga gccactaaaa tagtcgctac cgcgccgaca
      661 aaacttccaa gactctgaac tgtactctta gatatatctt ggatcatatc gcctgccgaa
      721 ttcatgaact tatcacctgc tgtttccaac tgttcgcgaa attggttgaa cagcgggtcc
      781 cgcaaaatct cggttaattt attatcaatc gtatctacat attgagggaa gttactgatg
      841 aagctcactg tttgttcctg aatcttaggg atgatcacta cgctccccca tgcgattagt
      901 gcaacaacca aaacaaacag cccaatgata ctgtaaagcc ttggtacttt tcgcttttca
      961 aagtaatcaa ctaccggatt catcaagtaa tacaagattc ctgctaaaat gataggcaga
     1021 cctacgattg ctaaaaattg ccagattggt gcaaacaaat atgaaacttt tgtaaataaa
     1081 aagacgatca gcaatattaa caatacaaca agtaaggctg tgactacttg attatttaaa
     1141 aaccagcgcc aaaaccacga taccggtctg ttcttcttat tttttccttc cataattcct
     1201 cctgttagtt ataaaaaatt tggcttccca aaccaatagc aggcagtcta tgcggatgaa
     1261 gatagattcc atttgcaatt tgtccttctt ctggacaagc atcaaaaatc aatgatacgt
     1321 gagctactgt ctttaaattc ccattggcca tcggaccgac ataatcgatc gtatatacct
     1381 gatcatcaaa agcaattgtt ccgcctgctt tcaaagaaaa aggttcgtct tttgatactt
     1441 cttgaatcac cgaatatttt cgtaaggcag ctgttgctgt tttatcgaac aaaatcagca
     1501 tgggttcttc cttgtttatt gcttctgtcc caatttctgt aatctttgcc tgaatcattg
     1561 cactctctcc tttaattgct ttcaaaaaca gtataacaca ttctcattct ttagccgtgt
     1621 ggaataatta tgtgatagaa taaaaacgaa aactatttca ttacaattag gaggaatcag
     1681 ctcatatgat cgaaaagata attttaggaa cctatacgcg tcgcgaaagt aaaggaatct
     1741 atacgatcga ccttgataca gaaaaagaag aattagccaa cctttcatta gctgttgaag
     1801 aaaatagccc tacctatgta gcaaaaagta aagctggcaa tctttacaca gttactagtg
     1861 tggatggatt aggtggtgcc ggtgcgtacg ataaggattt tcattttttg aatgcggtaa
     1921 cagagtctgg cgctcctttg tgttatgtag cggttgatga agcacgtcaa ttactatacg
     1981 gggcgaacta tcataaaggt gaagtaaatg tctaccatat attaggagat ggcgaactga
     2041 aagcagcaga ttcaatattc catcaagaag cgacaggtcc tcataaaaac caagatcatg
     2101 cgcatgtcca ctatacggat ctgactcctg accaacgatt agtcgtatgt gatcttggta
     2161 cagatcgtgt gtatacttat gatgtgtccg aaaacggcaa attgaatctt gtaactacct
     2221 tcactgcaga gccaggaaca ggccctcgcc atcttgtctt tcatccaaat ggacaattcg
     2281 cttatttatt tggtgaatta gacagcacag tccgcgtgct ttcttataat aaagaaacag
     2341 gtgcttttga agaattacag aaaatatcga ccttgccaga agaattcgac ggtgaaaatg
     2401 gaggggcagc tatccgcatt tcaaatgatg gcaagttcct ttatgcttct aaccgaggac
     2461 ataactcgat tgctgtattc gcagtttttg aagatggttc ccacattcaa aacaagcaaa
     2521 tcatctcaac agaaggggat tttccccgcg atttcgcact agatccaagc aataattttg
     2581 tcgtgtgtgc caatcagaac accgataatc tgacattata tcgccgtcat cctgaaacag
     2641 gattactgga attactgaaa aaagatgtct atgtaccaga atgtgtctgt gtttattttg
     2701 atcgttagta agaaaaggag aatgaaatga atcagcaaga cgtattagac agactacggg
     2761 aagaactaaa tattcctttc tttgatggga aaatcgaaga taaagagtat agcgaagagg
     2821 aatatcagaa actcaaagcc gatttacaga actactttga acaatatgta cagaatgtag
     2881 aaaactaatc agctttccat actatctgaa aagaacatca ggacaagact tttccgtcta
     2941 tcctgatgtt cttttctaca aataaaaaac cgccgagatg gttagactcg acggaaaagg
     3001 agtatttact cgattttgag taagtacaag gttgttgttg gttataggta tgtcattatc
     3061 ataaaggatt ttgatcactc tatcataaag gtaatattac atttatatta gataactcta
     3121 gtttttattg ttatcaaaga tttcttttat tttttcaaca acaaattagt cattttttgg
     3181 atggcagctg tcaattggtc tgtcgcttgg tcttgttttg cttcagatgt attgaataga
     3241 tcttcatcta cccctgattc aagatcgata ctttggatca tttcttcaca gcctgctaca
     3301 tatgaaagat aagctttttc aaaattttta tgaatgccca ttgcttttgc tggtggacgc
     3361 aaagtactga ctttcataag cattgcccga tatttttttg ttccttcttc aaataacagg
     3421 atgatctctt caagagtcga tttgtccagt tcacttgttt ttccttcatc aattgcgttt
     3481 ctgatcactt catatttcgg atgcattcct tctccgattg cttctgtttc cttgacgatt
     3541 tgatcgatgg actgcacata atagccaata ttcggtaaca tgttcgtttt cctactttct
     3601 ccattgttgt tattatttat tctacttgtt tttatcctca aatgacaagt acttgaaaaa
     3661 atttaatggt ttctatacag ctcgccattc ttattcgtgc tcaaagaaac catctgctaa
     3721 actatattgt ttccctgcga caatgtcata ttggatcaat tgatattcgt cgtaaatctc
     3781 ttgttgcgag cgattgaatt gcgcttcttt ataccactgt ccgttttgat agtacagttc
     3841 tcgttcaaac gccggaagtt cctgttctaa tgataaaagc agctgataaa agccatttgt
     3901 tgtctgattc gtctgttcca ttagattcgc tgcaaaataa aacggactgg tgattgcatc
     3961 gtgagtcgtt tgcttttcta attctccttt actgtcgaac ataagaaatt gtgtttcatg
     4021 caatgtttgt ttgtcatttt ttgcttggat cgtatctgaa tagatccctg gaagatgatc
     4081 cccccaaaaa acaactaaag tccttctaga aagattcttc aattcttccg tgaactgctt
     4141 cagtgccgtg ctgctatagg aaatatcttg cagataattc tctaagtcaa gtgtcccact
     4201 tccatctgaa gtttttgcag gatagtctag attatcatac tttccatcgt agggcatatg
     4261 tgtctgcatc gtgactaaat gaatgaactg aggtgttttt tcttccttga gaagtgtcat
     4321 tacttctttg taagctgact catcagaaat atatggatta ttctctatcg tatccgtata
     4381 ggtcatcgta cgctcgctga tgaactggtc aaatcctaat gtctgataaa catcctctct
     4441 tttatacatc gaagtattgt atggatggat cgctgtcgtc tggtatgatt gtgcgtttaa
     4501 cgctgaaacg atagaaggaa gctgatccat ttttggtaca agcatcgtgt aaggggtggt
     4561 gagttgcgca ttaaataacg ccatagaaaa accagtcaat gcttcaaatt cgatatttgc
     4621 tgttccaccg ccatagtttt gagaaagcat attgccacta tatgtttgat cagctacttc
     4681 ataataatct gccaatggct caccagatac ttctacgccg tttaatcgac taggatctga
     4741 gaaactttca ctcatcacga acacgatgtt cggcgactct tcctctacag ttttattttt
     4801 ttcatcggct agcttctggt atttttcagt gatttctttg atcttttctt tcgaatatcc
     4861 ttcaggttca tccattggtt ctaccttcag attgtacaaa aacccaccga taaaaccagt
     4921 gttatagtag ttcattttct ggctgtaagg tatccatagt gccgttttat tatatgcttt
     4981 tcgcaacaaa ttatcgggat tgttgaaatt actgatatac cctagcagtc caattgccac
     5041 aagcagtgtc gttaatcgga tcaattggaa tcgccttcct tttttcaggc ttcgaaacat
     5101 gtaccagcaa aacaatccta tcacggttcc tgcggcagct aagatcactg taaacagcat
     5161 agtgccggtc atatctttca gcaatccgat ttcagtgatc atcttcaaat cgtctggata
     5221 aatcggttct tgccgataac tcattttcat ataatttgca aaacctaata caccgatggc
     5281 tacgacatac gtaagggaac ctaaagggac agatcctgct agtgcaatca gaaaaataag
     5341 aataatcagc aagacgagac aggctaagaa gaatttttcc gtatgccaag aaaaagcaaa
     5401 tttcaacgca aggtctacgg atagatcatt ttgacaccac tgcaaaaata aattactaaa
     5461 aacaacaaga aaaaagatac tgatgattgc tgctgttcct tttaaaatct ttttctgttt
     5521 ggtcgaaagt ctgcttatat atcttttcaa atgcttgctc cttcatttct atcaataaaa
     5581 gaatgttgct tctcttattt tagttgtacg aaattcgaaa gtaaagaacg gaaagaagaa
     5641 ttaatgaaat ccaaatattc tctttcttta tggcctttct ggtttcttta ataagcggac
     5701 ctttcgtact ccagaaattt tttctagctg ttgtttcact tgattgagct gttcaaaatc
     5761 agtactgtct atgtcaatca atatgtagac atgctcattc ttatggttac gcgatatatc
     5821 tgcgatcgct agctcgttct cattcagcag agaaaatatc tctgctaata tattggtttt
     5881 cttttgataa aatatagtga atcgaaacgg cgcttggaaa aacattcgtg cggatggata
     5941 attgaccgct tctctaaccg taccgaacaa aagataatct tttaaggctt caactgccaa
     6001 acgtccgctg tctgccaaag cttcctgagt cgatccccta gatgaggcaa cataagtata
     6061 cggtcatttt ctaagaactc ttcttctgga aaatcagtca agtatttagc cagatgttgt
     6121 ttttccaatg cttgcataac agcatattta tcaacaattt cacttcttcc tacattgata
     6181 agtacagcat cttttttcat tttttctata ttcgcctgat cgatcaatcc ttttgtatct
     6241 tctgtcaacg gcagcatgac tacgatgtaa tccgaggtag aaagaactgt ttctaaatct
     6301 gcttgccgaa cataatccaa ctgggcatcg cggatagaat aacccaagac atccatccct
     6361 aagctatagc aacttagcgc tacttttgtg cctatcgctc caagaccaag aagaccgatg
     6421 gttttgcctt gcaattctcg tcccacataa gcacttcttt tgttttctgc ctgttctaaa
     6481 atattaggac ctgttagtgt ttgtaccata cgacttgctt cgattatcgg acgggaagat
     6541 aagagcaaac agcacaaaac aagctctttt actgcattag catttacacc tggtgtattc
     6601 atgacgatcg tcccgttttc agaagctttt tcaacgttga tcgtgttcac cccaacacca
     6661 gctcttgaaa ttgctagcaa atctggtgta agccattcat ctttcacttt cgtactacga
     6721 ataactattc cttcggctgg caaatcatct attattttga aatattcccc ttgtaacttt
     6781 tctatctctt gttctggaat agcatcaatc aaatgaacgt gatacataaa accccctcct
     6841 tactaacaag tatctcgaaa tttctgcaat tagacaactg tttaccattt gacttcctag
     6901 aagcaaaaag agcagttaga gcagagtagg ctgagtgata aaaataaggc tatgacaagt
     6961 tactgccata agccttattt tcgagagcaa aatattgagg gtgagatatc ttgataaatg
     7021 gtgttccgtt agctgacatt gataataaga ctaaatttca aaaaagttga aaagcaaatt
     7081 tcgtcaatct cttcttattt cttaaaacta agtggctttt tcacaacctc tttttatcta
     7141 ataaccactg tttccaactc aactaatttt gcccacgttt caatttgatc tgttgttaga
     7201 tttagcgaga caacggtatg atgaccgcca cctgcctgaa tccatgaatg gacaccttca
     7261 tggaaattcg gtttagtttt ccataacaca cgtgcaacag gtaaattagg tgcttcagtc
     7321 gttggttcaa aggcttctac ttcattgatc agcagtttat aatgcgtacc gaaatctgcc
     7381 atcgatacga ctaccccttc tcctgctttc ccatcaaata caagacgcgc cggatcttct
     7441 ctatctccca ttgataaagg agaaacaacg attcttggtt tcgtcgcagc aagcgtcgga
     7501 tctacttcca tcatatggga ttccaagatt gcttcttggc cactagctag ctcgtaagta
     7561 taatcttcca tgaatcctgt atctttccct cgagccatga ttttcagcaa ccgatcaatc
     7621 gctgcagttt tccagtcgcc ttccccagca aaaccgtatc cttctgccat caaacgttgt
     7681 acagctagtc caggtagttg tttcattcca tacaggtctt caaaattagt cgtaaaagcg
     7741 ttatagcctc cttcttctaa gaaacggcga ataccgattt cctgctgagc ttgtactttt
     7801 acatgttcct cccatgtctt ttcttcataa tcaccatagt cgaaggtata caattccttg
     7861 tactcttcaa ataattgatc gacttcttcg tctgatacgc gatcgattac ttgtacaaga
     7921 tctccgatac caaaataatc aacagtccaa ccaaattgaa tctgtgcttc cactttgtct
     7981 ccttctgtga cacccacgtt tctcatgttg tcaccaaaac gagccacttt tattccaaaa
     8041 ctttcattat aggctactgc aacatccatc caatcagcaa tctctttttg gatctcaggt
     8101 cgtttccagt agccaacgac gattttattt tgtttattta atcgagcatt gatgaaccca
     8161 tattcgcggt caccatgagc ggattgattt aaattcatga aatccatatc gatcgttttc
     8221 caaggaatgc tttcgttata ttgcgtagct aaatgaagca atggtttttg tagaagcttt
     8281 gtcccgcgga tccacatttt tgctggtgag aaagtatgca tccaagtgat cacacctgct
     8341 acttcttctc gataattgac ctctttcatg atttttgtga tcgtatcagc agtaactgct
     8401 aattcttgaa ggcggattgg ataaggcaat tggccatttt cattcagttc atcgaccatt
     8461 tcttgtgcat gtttctttac ttctcgcagt gcttcttccc catataaatg ctgtgatcct
     8521 acaacaaacc aaaattcttt ttctccaata ttcaacataa ttagccactc cttttatttg
     8581 ttttgtccgt aatacgcatt ttttccgtgt tttcgtaaat aatgtttatc taaaatccgt
     8641 tgaggcagct cttctgaaaa tgaattgagc tgtctggtaa ataaattcat cttgcatact
     8701 tcatctagta cgactgcgtt cattaccgca ctttgcgcat ctttccccca agtaaatgga
     8761 ccgtgtccgt gtaaaagtac ccctggaatt gctaagggat caattttgcg ttctttgaat
     8821 gtttctatga taacttttcc tgtttcatat tcgtacccgc tgtcgatttc ctgttgtgtc
     8881 aaaaatcgag cacaaggtac cgatccataa aaagtatctg catgcgtcgt ccccatcgca
     8941 ggaacatcca atcctgcttg tgcccagatc gtcgcccatg tcgagtgagt atggacgatt
     9001 cctccgattt gaggaaatga acgatataaa acagcatgag taggcgtatc cgaagaggga
     9061 ttgagtttac cttcaatgat atgattgtcc aagtccacaa cgaccatgtc gtctgctgtc
     9121 atctcttcat aactgactcc gctaggtttg ataacgaaat atcgtgtttc aggatcaaaa
     9181 gcgctcacat ttccccatgt atatttgacg agtccgtgtt taggcaagtc aagatttgct
     9241 tggtatactt cttctttcag ttgttccagc attttctatc actccttttt cttgcaattg
     9301 atgaatcgct gttttttcaa tgtcgatccc ctcacggtaa cgtctcataa atatctgata
     9361 gcctgctatt tcttctgctg aaggtgtgat ggtgattcct tggtcttgtc caaacacgtc
     9421 ttctgccaag aagttttcta aagacttccc atgtcgatcc atcatatagg ctgctaataa
     9481 cgcgattccc cacgctccac cttctccggc tgtgtccatc actgtaactg gtgcctccat
     9541 agcagatgct agaatccgct gtccaacttc tggtgtttta aaaatccccc catgccccac
     9601 taaacgatca atttggacat tctcagattt caatatatcc attccgattc tcattgcacc
     9661 aaaagcactg gctaaatgga tccgcatgaa attcgctaaa tcaaaacggc tacctggtgt
     9721 acgtacaaat aatggccttc cttcatttac tcctgtaatg ttttcaccgg aaaaataacc
     9781 ataagaaagt aatcccccgc aatccgtatc gccttctagc gctttgttga ataataccgt
     9841 gaataattta tctctgctta tctccatacc caaagaattg gtaaattctt caaaaatact
     9901 gacccaagca ttgatatccg aagagcagtt attcgtatga accatgccta ctagttctcc
     9961 tgaaggtgta gtgaccatgt cgatttccgg atggacattt tctagttctt tttctaatac
    10021 gatcatagcg aaggcggaag taccagccga aatgttccct gtccctttgg ctacactgtt
    10081 cgtagcgacc ataccggttc ctgcatcccc ttctggcgga caaaccggga ttcctggtct
    10141 caaatttccc gtagggtcga tcagataagc ccctgattcg cttaacttgc cagcttcttc
    10201 tcctgctact agaactttag gcaaaatgtg atccaagtca atcgctacgt gcgctttttc
    10261 gattaactga ccaaaaatat ttttcatttc ttgatggtag gttttcgttg aaggatcgat
    10321 aggaaacatg cctgatgcat ctcctacgcc tagtactttc tcaccagtaa gctgccaatg
    10381 gacataacct gcaagcgttg tcaaaaaatt aatttctttc acatgttctt ctttattcaa
    10441 aatagattga tacaaatgag cgatactcca tctctgcgga atattgtatt gaaatttttc
    10501 cgttaatatt cgttctgctt cttcagtgat tgtatttcgc caagtacgaa atggtactag
    10561 taactgttcc ttgctatcaa atgctagata accgtgcatc attgcactga acccaatcga
    10621 cccgattgtc gtaagattct cgccatagat ttcgaatact tctgctgcca tttttcggta
    10681 actgacgcgc agtcctttcc aaatatcttc taatgaatag gtccagatac cattttctag
    10741 tttgttttcc cactcataac taccagcggc aataggagta aaagatgaat caatcaatac
    10801 agctttgatc ctagttgatc caaactcaat ccctaaagat gtacgaccat ctatgacatc
    10861 taacatactt tgcgcattta cttccttcat aatgatttaa ctccctcctt ctcgtcaaac
    10921 ctgatcaaac cgtcttttta gtagcgctta caatgattat tgtatacttt tgtacgtaca
    10981 tgtcaagcag ttatttacaa gaatacaata aaaaacactt gttttgtacg tacataagtt
    11041 ataaaatgaa attgcttaca aaatctgatc aaccgccttc tcgaaattct agaaggagag
    11101 aatacttatg aaaaaagaaa aaaaagtttc ctcatcgttt atttattttt ttggcgcatt
    11161 tggcggcatt ctatttggat atgatattgg tgttatgacc ggcgccttac cttttttaca
    11221 gcatgattgg ggtttggcag gtaaagcttc tttgatagga tggatcacgt cttcggtcat
    11281 gttaggtgcg atccttggcg gctctttatc tggtcttctt tctgataagc ttggacgacg
    11341 aaaaatgatt cttctttctg cacttatttt tatggctggt tctgtccttt ctgcatctgc
    11401 ccctcacaat ggttcttatt ttctgattgc agcaaggatt cttctaggtt tagctgttgg
    11461 cgctgcatct gccctagttc ctgcttatat gtctgaaatg gctcctgcta gactaagggg
    11521 aagattgtca gggatcaatc aagtgatgat tgcttctggc atgctccttt cctatgttgc
    11581 agattatttg ctaaaagggt tgcctgaaac gatggcttgg cgcgtgatgt tagggctcgc
    11641 tgctgtcccc gcgctgattt tatttttcgg tgttttagct ctaccagagt caccgcgttt
    11701 tcttatgcaa tctggccgct tggaagaggc aaaaagagta ttgaactata ttcggacacc
    11761 aaaagaagct gaacaggaat tcgaacaaat ccagctgaat gtcaaacaag aaaagacaac
    11821 cggaacttct tggcatactt tgtttttaga aaaatatcgt tccttagtca ttgccggtat
    11881 tggtgtagca gtattccagc aatttcaagg agctaatgct attttttact atattccgct
    11941 gatcgtagaa aaagcgactg ggcatgcagc gagcgatgca ttgatgtggc cgatcatcca
    12001 aggaatcatt ttagttgctg gttctttgct ctttttggtt attgcagaca agttcaatcg
    12061 gcgaacttta ttgaaaatag gcggtagcgt gatgggactt tctttcatcc taccagctgt
    12121 tttaggaact gtactggatg ctcatacaaa ttcgttgttg attctcttgt ttttatgtat
    12181 ttatgtcgca ttttattctt gcacatgggc tccactgaca tgggtaatcg taggcgaaat
    12241 attcccacta gctgtccgcg ggcgagcatc tggcctagcc tcttctttta attggattgg
    12301 ttctttccta gttggcttgc tttttcctgt gatgactgct tctatgtctc aagaaatcgt
    12361 tttcggcatt tttgggatca tctgcttttt aggggtttta tttattcaag agatcgtacc
    12421 agaaactcgt gggaaatctt tagaggaaat cgaacaaagt gcatctaaaa aaacttatcc
    12481 taaacgtatt tctatccatc attcttaaag aggttgtgac agaagtggtc agcttcaaga
    12541 aataagaagg aaccgcttag tttccagtca caaggaacaa tttcaaaaaa cagcttctca
    12601 tgtttgatga atattgtgac ttgtgaccag ttggtaggag aacaccgttt agtggagagg
    12661 tggtgaaaga aacgttcagc cttgagcgat gacaaaagct ctcacaaaca ttgcgacgag
    12721 taaccgtagg agcaataaga ggcggtaaaa acccgtctct tatttttcgt tttctttcac
    12781 tgtttcccgt tcaactagta caggttcata gagaatattt ggctgtgcct gtcctttttc
    12841 aatcgttgtg acgatccacc gtgcggcatc ttgtcccaac ttttcttttg gatgcgtcaa
    12901 tgttgtcaat tttttattcc ctaaatggct taaagaagaa tcgtctgttc ctacgatcga
    12961 taggtcatct ggaatatgat agccattttc tgtcaactta tctagcatta aactagctat
    13021 ttgatcgtta tagcaaatga tgccatctaa agcttgttct tctttcaacc gttgtactgt
    13081 tttttcagcg attgtttctc gtgtttccgt ggtgaaagta atgatatctt ccgtcaaaaa
    13141 acgcacatta tactgttcac acgcgctgat aaaacctttc atcctgtatt ttccttgaag
    13201 atcgtcgatt tttgtgatga acaacagacg ctgatgtcct ttttttatca aatattctgc
    13261 tgccataaaa ccgactttca catcatctaa acaaatataa gaggcattta actcttcata
    13321 agcagcattg atcatcacca tcggaatgcc ttgttctctc aaagcaacat aaagtgctaa
    13381 gtttgggtta tactgattac ttttcgtagg ctcaacgatc aaaccatcta ccccataagc
    13441 aatcattttc ttcaaacact ctttctccaa ttcgtgatcg ttattcgtac tggctaaaag
    13501 caatgaatac ccagattctc gtaattcatt ttcgattcct cggataatcg acggaaaaat
    13561 ataatcagag agatatgtgg tgatgacacc gatcgttttt gttctgttca atggtgtttt
    13621 ttctttctta tagctgtcat ctacatatgt gcccgaccct ttttctttac gcagatagcc
    13681 ctcatttacc aacacagcga ttgcttgccg aatcgtatgt ctgctgacgt catatatttc
    13741 ttgcagcttg aattctgagg gaatggttgt atttacttcg tattcctcac gaaggatctt
    13801 ttgttttatc tcttctgcaa tatcttgata ttttgccatt tgccttgccc ctttttattt
    13861 gtacgtacat atatcataac gagtctgcaa ggtttattca agcaaaaatc aaggtttctt
    13921 gtgctcataa ggcatacgga acaggttcac caaattctgg aaatccttgc tcattccacg
    13981 taaagcattg cgcgttcgcg tgccgattag gattgtctaa cggatcccct ttttggttct
    14041 tctctggtcg agcatgatag atcaaagtat caaagcaccc gtcttctgaa accgtaaacg
    14101 agttgtgacc aggaccaaat tgcttatttt tttcagaaga aacgaatact ggctccgata
    14161 atttatgcca tgattctttt aataaaagat tcttgtgctc atcagcccac agcaggccca
    14221 tggcatagtt ttcatctgtt gcactaccag aatacgtaat gaatattttc ccattgcgag
    14281 taaggactgc tggaccttca tttactgaaa aaccccgttt ttcccattca tactcaggta
    14341 tagaaaggag gatctgcttc ccctttaacg tccaaggatt atccatttcg gatagataaa
    14401 gattagaatt cccagtaatt tcaggatctt gttgggccca cacataatat agctttcctt
    14461 gagaagagaa agttgttccg tctaaactga aagtttccct tttcgttttt atttgtccct
    14521 tttctatcca atctgtattc attggatcta tatgctgatt ttcaagtacg aacatgcggt
    14581 gatgatgaga ttcatcacgt atagttttat gattgcttgc agcaaagtaa atataccatt
    14641 ttccattgat ataatggact tcaggtgccc agatcaattc actcatcggt ccttcttcat
    14701 gagcctgcca tacaatcagg cttgcagcat gttctaattc attcagtgac tttgcccttc
    14761 ttaattcaat cacttggtag cctggaaccg atcctgtaaa ataataataa ccatctgtat
    14821 gtttatatac ccaaggatct gcccgttgcc gaacgatagg attattataa agtgtcttca
    14881 tcataacaaa tttcctcaca ttttctttat tctaattaca ttccaagagt atttttctat
    14941 ccctacattt aattcgtcat gtttttctat tgaaaaatag tttatttcag gttttatttt
    15001 ttctggttct tcacgtgtat ttttgtccaa cagatcgcta ctggttaatg tgtagtgctc
    15061 tccttgatct agcaaattga aatcatgttc aatcgttatc ttttgttgtt catttgtgcg
    15121 attgatcaag aaaatagtca gctgattgcc gttatctacg atcacactgt ccacataagg
    15181 aacatttttt atcttttcac aatcataaac agggcaaatg atttgttgtt tcaatacttg
    15241 acctttagca tatttcgata agtgttgcat cacataataa gttggattcc tccatgcttg
    15301 tcctttagca tctgtcagta ttaaaggtat tgtgtttact aacaatgatt gacaactaat
    15361 ctttacgcga tctgcgtgtc gtaaaatagc cagccctaat gaaccaaata ataatgtatc
    15421 ttccatagta aagtaacacc aatcgatggg actaccgact tcaaaatccc tatgtctttt
    15481 ttccggttgg gcatgtacat tccattcatc aaacgctaga tacattgttt tctcacttct
    15541 caaatatcct tttacataat cacaagtagc aacgatttct tcaatttgac gatcgaatcg
    15601 ataagctttt gcaaggtatg tcgctgtatc atcacgctca tttttaggag gtttagtcaa
    15661 gtcttcttca tcatacttat caatatagtt atgcaaagct aaataatcta cattctcata
    15721 agcttcttct aatgcgatac gatcccattc agggtacgat ggtaaacgtg gcgtagagct
    15781 tccaactaag attgtttcaa ttgaatcatc cactaacttc atgacttttg aggcttcatt
    15841 tgctaaccta ccatattcat aagcactctt agcccccact tgccatggac cgtctagctc
    15901 attccctaaa caccataatt taacgccaaa aggctttttt tgcccatttt ttattcttaa
    15961 atcactccag aaggttcctt ttggaaaatt acaatattct actaaatttt ttgcttcatc
    16021 aattcctttt gttcctaaat tcaccgtgaa tatcggtttc gcttgtacat gactgatcca
    16081 tttaaaaaat tcgtggagtc caaaagaatt tggttctata cctcgccatg ctaaatcaat
    16141 tttttttggt cgttgttctt tcctacctac agtatccacc caatcataac cagatgtaaa
    16201 gtttcctcca ggatagcgaa tgacacctaa ttctaattcc tttacataag agaggacatc
    16261 ttgtctaaac ccgtcaccat cagctgtttc atggcccggt tcataaatcc ctgtatagac
    16321 gacacttccc atatgctcaa caaatgagcc aaacagccga gaactgatct ctcctaccgt
    16381 aaaatcctct ctgattttta ctttcacttc ttcgtccaac agctttccct acctttcatt
    16441 tcctatagtc aagataatag atacaagttt ccatacgcca ccagcaaaga taaaaataaa
    16501 aggagggaaa agaaatatga gcagtacaaa tcctaataac aatacgcaac aaagaatatt
    16561 tctcaaaaaa tcaaaaaata ctttccatgc actttgttca aaaatttgta aaaatgtgat
    16621 atctttgttt tcagaaatca catatatcca ggataaaaga aacatggaat aaataagtaa
    16681 aactacatat ccactaattg aaagtacgat tgtctgttct tctaataatt gattaacaag
    16741 aaaataaata atgatcgtta acagactaag gaacaagttc ttaccaaaat gttgctttat
    16801 tccttgaaag aaaaaataaa tgatatttcc tgatccctca cctttccatt gcgccattac
    16861 ataaaaaaca gcacatgtag caggcacgat agtaataaca ggcaaacaca cgattaccca
    16921 gagaatacct aataagatgt aatcagaaac cacaatcaac tgtccataaa gtttagtctc
    16981 aactattttc atcttcctca ctctttcatt ccagacatag ctgttccttg aacaaaatat
    17041 ttctgtgcaa aaatataaac cactagtaat ggcagcattg aaataaccgt tccagccatt
    17101 acaggtccat aaaaagaaat gttctgccct gtaaataaag ctaaccctgc tggtaaagtt
    17161 ctcatttttg aactacttgt caatatcaat ggataaagca agtcattcca actattcatc
    17221 agcgtgaaaa tccctaatga taaaagagta ggtttgctca atggcaacat gattttcaaa
    17281 aaaatattaa actcacttaa tccatcaatg cgtgctgcct cttccaaaga atctggtaaa
    17341 gtaataaaaa aggaacgcat catgaagata ccaaatgcag ttgtcatacg aggaatgatc
    17401 aaacctgcat aagtatcaag catgccaagc aaattgactt caataaatag aggaatcatg
    17461 aagacttgga atgggatcat cattgtcagc aaaacgaaat agaacaaaac tgattttcct
    17521 ttgaaacgca tacgagcaaa tgcatacccc gcaagagaat caaagaatac agaagtgatc
    17581 actgtccctc cagcaaaaat cactgtattt ttgatgtaat ctaataaagg gatcgttgtc
    17641 caaaccttaa tatagttatc tagggtatag ctatctgcaa atattctagg cggaaatgag
    17701 ataatgtctt tttcgtgttt aaaagaagaa ataatcagcc acaaaaaagg aaacgcaata
    17761 accaacaata taactagcat actaatcgtt cgaatgattt ttttaccact aactgctttt
    17821 cgactattca cagtaactgt aatcgagctt tctggtgcca tacaggtttc cctcctattt
    17881 catttgtttt tctttccgtg acatgtacac attagtggag atagctatag ttgcaacaat
    17941 gataaacaaa accgaagaca gtgctgatgc atagcccaat tcataaggtg ctgtaaatcc
    18001 tcgactgtaa atatattgaa cagctgtttc tgtcttaaat tgtgggccac cagcggttgc
    18061 aacatatact tggtcaaaca cttgcatcga accaatcaga ttcgttaaaa tacaaaaacc
    18121 taaggaggga acgatctgag gtagcgtaat gttaaaaaac tgctgtcgat ttgttgcacc
    18181 atccatttga gcagattcat acaaagaggg agagattccc tgaatagcag tcaagagaat
    18241 cgtcatagta acaccaaaat tcttccaaac agtcatgatg gctaccgtcg gcatagcaag
    18301 ggttggatcg cgaaaaaatt gagggatcgg caagccgact tgtgaaaaca agtaaggaat
    18361 cgcccctaca ttcggatcaa gcaacataga aaaaataatc gcaattgacg tcaatgaaca
    18421 aataactgga atgtaaaatg tcgaacgaca aaaacgattg aatctggtat ttttagataa
    18481 tgctactgct gctaataaac caacgataat ttgtgttggc gtttcgagta cggtgaaata
    18541 taaagaatga atcaacgaat taactgctcg ttcatcacta aatatacgtg tgaaattttc
    18601 aaaacttaca aaatttcttg atgtaaagaa aatattcaaa tctgtaaaac taatagcaaa
    18661 tgttcctaaa agcggtatga cagtaaataa taataaaact aaaaaagatg gagttaaaaa
    18721 caaatacgca gcacgatcag gacgattcca atatttggtg aatccgttca tatagtccac
    18781 ctcatctttc attttgataa aatatacaat cttggtttaa acgaatctga ataagatatc
    18841 cgaacaatcg ctgtgatttt tgcaataaca cctatctgca aatactaggt cgatcattca
    18901 gatatctgta tcttgccaac agtctatcct gtataaagtt ctgtactatt tttgcagtaa
    18961 ttgattgatg gcatcatctg catcgttcat gagtgtctca ggatcttctc ctgctaataa
    19021 tttttcaatc agtggattga tgatatcgtt attgatcgca gagatttggg taaaacctgg
    19081 taaatatggc tctgcatagt ccatttgttt cgataattca gatacaatag gatcattttt
    19141 tacttcttca tcttttgcta ctgaatccaa gtaggcagga aaaccatttt cgatactcca
    19201 ttttttacca atttcagttg tattccaata tttcaaaaac tcatagacag cttctttttt
    19261 attattatct gtacttgccg gaatggcata tcctacgcca tctaaaatag ctgttttttt
    19321 gtctgaatca ctcccttgtg gtaaggtagt cacattataa tcaatctcgt ttgctttcaa
    19381 tccgttattt aaccatggcc cattgatttc aatggctagt tgaccagcat tcattaaatt
    19441 gtccatttcg gcgccagaaa tcgattctgg accagtcttg tctacatgga tcattttttg
    19501 gatcgctttt aacgttttaa ggttctcagg agacgcaaat tcagacttag tataatcatc
    19561 gttcactaat ttaccgccat ttgctaacat ccagttatat aacggtgcag ttccatcctt
    19621 attgaagaca aaacctgata catttttact actatcagtt aattttggtg ccatttctgt
    19681 caattcttcc caagtagtag gtggttgttc agtatctaat ccagcttgtt taaacaaatc
    19741 attattccaa tacatataca tgccttgtac ctgcatgggg acaaaatact gtttaccttc
    19801 tacttcacct aattcaatag ccgtttcttt aaaatcagat ttatctactc catcatattc
    19861 ccagaaatcg tctaatggtt gtaccgctcc gttttctaca tactgtgcaa aatctggata
    19921 atttaatgca ataaagtcag gtgctttttt agaagaaatc gctgtaggaa gtttttcatt
    19981 caaattggcc caagtcatga tatccatttc aattttgatg tttttatcat ttgttttatt
    20041 aaattcatta acgatttctt gcaatatttc accatcagat gcagtaaacc cattccaaaa
    20101 agtcaaagtc acttctttat cagaatcaga ttctgctgaa cttccgccac cgcaagctcc
    20161 taaaatacct gttgcagcta ccaacaaaga gccaattaac cattttttac ctttcatttt
    20221 ttgttcctcc ttcatctgat aaacgacatc tgaccacatt ccaagatagc ggtttcaata
    20281 aacaattgat tttcccatct tcagctttta catttgttga atgacttggt tttacttgtt
    20341 cacttttagg aagattagtt gcttttgtat caaatccact catttcagaa aaatcaatca
    20401 ctccctctaa tgataattca gacaagtgaa cagttagatt catttcttct tctccacggt
    20461 taactgcaaa tatgacaagt tctttgtcat ttattacggc tatactttct aaatacggca
    20521 cttcttcaaa atcttccgtc gcatagtttg ctgaacgaat ttgtgggctt aacacctctc
    20581 cttgtccata cacagcagct tgcataaatg gataatagat cgtctgtctc caagcttctc
    20641 cgtttgtttc tgtcctgatt ggtgcaataa catttaccaa ttgagcaaga caagcaatct
    20701 ttactctatc tgcatgtttc aataaagtga ttaatagaca gcctaatagt aatgcatctt
    20761 caaaattata gttatcttct agtaaaggag gagcaatctg ccaaggcgct gcttgctcat
    20821 cttgttccgc tgaatgatac caaatattcc attcatcaaa ggacaggttg atctgcttct
    20881 tactatgttt cttcgccttg actgtatcgc acatcgctgt cacttcagaa atgaaccgat
    20941 ccatgtctaa ggaacgtgca agataatgag aaagatcatt tttttggttg ccataatatt
    21001 gatgcagaga caaataatct atttgatcgt acgcttgatc aagaactgtt aactcccaat
    21061 caccaaatgt aggcatttgc cgattcgaac ttccgcataa aaccacctca attgaatcat
    21121 ctacgagttt catcgcctta gccgtttcct ctgctaaccg tccatattct tccgctgttt
    21181 tatgtccaat ctgccaagga ccgtccattt cattccctaa acaccatgtc ttaattccaa
    21241 aagggctctc ttgaccattc gaacgcctta aatcactcca ataagttcct ttaggaaaat
    21301 tacaatattc gactaaatta cgagctgcat ctactccacg agtacccaga ttgacagcca
    21361 tattgatttc ggcccccaca tgctgacacc agttataaaa ttcatgaatc ccaacttcat
    21421 tcgtttcaat tgtccgccaa gctaaatcca accttctagg tctatttgct atgggcccaa
    21481 tactgtcttc ccaacgaaat cctgacacaa aatttccacc aggatatcta atcatgggaa
    21541 tgttcaattc ttttaccaag tgaatgacgt cttggcgaaa tccactttta ttagctgatg
    21601 gatgatctgg ctgataaatc ccttcatata ctgctcgtcc catatgttca ataaatgaac
    21661 tgtacaaccg cggatcaact ttgcctacac gcttgacact actaatcaac attgtggctt
    21721 ccataactga cctcctttaa tttatacatg aataatacac ctcgttgaaa gcgttgtcaa
    21781 taatataaat gttaaactta cttatttttt atcgatttta attaaccaaa atattaataa
    21841 tgattaaaac aaataattta atataacttt tattaacaaa tatgttaata tataagaaaa
    21901 accttttaag aggtgatata tatgcaacta caaataaacg aagaatcctt accggtatat
    21961 gaagcattag ctagtaaaac aaggatcaag atcatccagc tactttccaa aaaaaagatg
    22021 aatgtcaaag atttggcaaa agaacttgga gtgagcagtg ctatcacgac gatgcacgtg
    22081 aaaaagctag aggaagcaaa catcatcaaa acagaaaaag taggacaaca aaaaatttcg
    22141 agccttcgtg tcgataaaat cgatatcagt tttccagaaa aaatattcaa tgcttttgat
    22201 acgaaagaaa catcgatacc tattggtcac tatacaaatt atgcaattga accaacatgc
    22261 ggtttagcta cgatccatga ttttatcggg aaagtggatg aaccacgcta ttttatggat
    22321 cctcgaagga tggatgcccg cattctctgg tttaccagcg gatttgtcga gtatcaggca
    22381 cctaattttt taaatacaga ggatacattg gagatgttgg aagtttctgt ggaaatttct
    22441 tctgaatttc ctttttcaaa tgacaattgg ccttcagata tcactttcag cctaaatggt
    22501 gtggagctag gaacatggac gagccctgga gattttgctg atatccgcgg taaatatacg
    22561 cctgattggt atccagataa tcttaatcaa tacggcttgc tgaagacgat ccgaattacc
    22621 aaacacttga cgaatatgaa tggagaaccc ttgtcaaaca tcacgatcaa cgacatccct
    22681 aaagagcaag acacttggca tttgcgaatc gaagtgaaag acgatgccaa acatgtgggg
    22741 ggctgtactt tatttggtaa aggattcggt aattacgatc aggatatcaa attaaaagtt
    22801 tactacagct gatatttttc ttttctattt tataaaacaa aaacagccaa tccctatgaa
    22861 gggacggctg tttttgcttt attgttattt ccagaaatca tccaaaacgg aaattggcaa
    22921 atgtcgttta tgttgtgtct tgttccacca tgcttcgatt ttttcttgtg cttgagcggg
    22981 aacttctttt ccttctagat aatcatcaat ttcattatat gtgacaccta gtgcgacttc
    23041 atctgcaatc attggtttcc catcttcaag atctgcagtc ggaatttttg tgtataattt
    23101 ttccggtgca ttcaatgctt gaagcaattg tttcccttgt cgtttgtcca aacggaataa
    23161 tggcaaaatg tcggctccac catcaccaaa tttcgtgaag aatccagtaa tgttttctgc
    23221 agcatgatct gtccctaata cggctcctgc tctttctcca gctacggcat attgcgtaat
    23281 catacgttga cgtgctttga tatttccttt gttaaaatcg ctgattccca cacctgcttc
    23341 gcttaatact tgtacttgtg catcaacagc tggtttgata tttactcgca gactaacatc
    23401 gggctggata aagtcaagag cagcttttgc atcttcttca tctgcttgtt caccataagg
    23461 aagacgaaca gcgataaatt gatagttttc atcttttgtt tcttcacgca tttcttccat
    23521 cgttagttgc gccaaacggc ctgctaaagt agaatcttgg ccgccgctga tacctagtac
    23581 aaaagtttta agaaacggat attttttcaa atatgctttc ataaagtcaa tacttttacg
    23641 tatttcttct tttggatcaa ttgttggttt gacacctaat tcattgataa tttctgtctg
    23701 caggctcatt tattctcctc ctatgcttct gtatgaagtt ctgctacgct ttttttcatt
    23761 cgttccatga tagccatttt atggttccag cattcagtag acagatcgac tgggtatttt
    23821 tgcggattca agtctcgttt atactcttcc catagtgaat ctagattttc ttttgtatat
    23881 tctttgattt cgtttagtgc aggtaattcg taaactcttt ttccttcgat aaagatatct
    23941 tgtaaaactg ggcgagctgt aaagtctcga acagttttat tgataaacgt atgcactgga
    24001 tggaacatga agatagcttc ttcttctcga gggtcttcat cccataatgt cacgtagtct
    24061 ccttcagatt tcccatcaaa atttcgagtg atgcgccaca cttgtttttt ccctggagta
    24121 gttacttttt ctgcattgct tgataacttg atcgtatcca tcatttttcc ttcatcatct
    24181 tcgatcgata ctagcttgaa tactgcacca agggctggct gatcataggc tgtgatcaat
    24241 tttgtcccaa caccccatac atcaatttta gctttttgca tctttaaatt caaaatcgtt
    24301 gcttcatcca agtcattcga agcatagatt tttgcttccg taaatccggc tgcatctaat
    24361 tgttcccgaa cacgcttaga tatataggcc atatctccac tgtcgatgcg tacgccttgg
    24421 aagttgattt tgtcacctaa ttctttcgcc acgcgaatcg cacttggcac acctgatttc
    24481 aacgtatcat aagtgtcgac taagaacacg cagtctttat gggttttagc gtaggccata
    24541 aatgcttcat aatcatttcc ataagattgg actaacgaat gagcatgggt cccgctagct
    24601 ggtatcccaa atatcttccc agcacgtaca ttgcttgttg catctgctcc gccgatatat
    24661 gccgctctag ttccccagac tgctgcatcc agttcttgtg cccgtctagt tccaaattcc
    24721 aatagtggat cttctccgat gacagatttg atacgagctg cttttgtcgc gatcaacgtt
    24781 tggaaattga ccatattcaa cagtgctgtt tctactaatt ggcagtgcgc taaaggccct
    24841 tccacttgga ttaatggttc atttgcaaaa actagttctc cttcacgagc agaacgaact
    24901 gttgctttaa attcaaaatt ttgtaaatac tccaaaaaac cttcaggata gacttctaat
    24961 ccacgcaagt aagcaatatc ggaatcattg aacgtcagat tctctaaata attgactaac
    25021 cgttccaatc ctgcaaaaac cgcgtatccg tggttaaaag gcatttctcg aaagtaacat
    25081 tcaaaaacag catgtaaatc agctcgacct aattcccagt atgtctgcat catattgatt
    25141 tgatatagat ccgtatgcag cgtcaaactg tcgtctgggt aagtattatt catcttgtat
    25201 tactcctctt ggcaagtttt catttcctac ccattataac aaaaaaaatt aataggaaaa
    25261 gaaatcttcc attttttctg aaaaagcaca tgttttacgg atatttcttg ctaaaaatga
    25321 actccatctg ctaaaactat cctttcttat tggtatttaa cctaaacgag aaagaatact
    25381 tattttattc aatgtatccg agacacgaag aaattagcgt tttctatttt tcttacttga
    25441 taaaataagt agattttcct actacaatcg tagccgttaa gataccgatg attgaacaaa
    25501 tataaccaaa tgtctctaca acataatcaa tggcaaaagt ttttgaagca ataatacgtc
    25561 tttccttttt tgcttcttat ccccaaagaa acggatataa cttattatgt attgaatttt
    25621 tttggaaagg cgaattatga caagatatac cttgcgttga aaaaactcgc ggaaaaaata
    25681 tcacacgttt ttaaaaagat acaaagtaag aaagcagctg tcaatagaat ggaaacaaaa
    25741 atggcgagac atcaatcagt ctcgccttgt tttttattgt atacattaga tatggagcag
    25801 gttaccataa agatgattat tagtcgttat taaatagaat ccttcgtatt tttttgttct
    25861 atcactacaa tatctttatt tggacgtttg aattgtattc cggcacgttc tagctcctgt
    25921 ttcactccta catggacttt gacatcttct cgtgtcattt ttaaaacgtg atgaatcgca
    25981 tagtcgattt cttgccttgt gatttttttc ttcgtattga tcatcacgac ttgcttttta
    26041 tcatatgtgt ctaccaatag cagttgtgtt cgatctaacg aaaataattt gtaataatta
    26101 atagccgtat tcccaaaaaa gaattccact actttaggat aaaatgtctt aatatttaaa
    26161 ttactattca caggtgtttc gattagcttc atctcattcc tcttttctat atagtcgatt
    26221 tagatccaat cttaagttat gttaccatct ttcctagcat taaggaatcg gttacaattg
    26281 aacctttaaa gacaaaagga tttacctttt atcacttaat agtataacat aatttcgtga
    26341 gaaaaaaata caattttttc ttgaccatct cgttacgtaa aggattatgc ttacatttgt
    26401 caggaggaaa aataatggag tacacaataa agaaaatgtc agagatatca ggagtcagtc
    26461 cgagaacctt gcgcttttat gatgagattg gactgctaaa accagctagg atcaattctt
    26521 caggttatcg gatttatggc aaaaaagaag tcgatcgtct gcaacacatc ttattttatc
    26581 gaacaatggc attcaagttg gatgatatcc aagaggtctt agacaatcca tcttttgacc
    26641 accagaaagc tttaatcaag catcagcaaa tgttgctgga aaaacgggca caaatcgata
    26701 ccctcttgac aactgtccaa cagacacttg atatgtacga aggaggaaga aaaatgagtg
    26761 acaaagaaaa atttgaaggg tttaaacaac aaaagttgaa agaaaatgaa gaatcctatg
    26821 gacaagagat tcgacaaaaa tacggaaaaa aaaaggttac agcatccaat gaaaaatgga
    26881 tgaatatgga taaagaaacg tatgaagaaa tgcaaactgt tgaaaagcag atgttatttg
    26941 atctcactct ttacttaaaa gaaccagaag atgaaagctt agcagaccgt atcttccaag
    27001 ctcataagaa gtggttctct tacagctggc ctgaatatca gccaaaagcg cataaaggac
    27061 taggaatgat gtacgaagcc gatgaacggt tcactgcata ttatgacgag cgaagtggtc
    27121 atggtgcagc aaaagcttta aatgaaatta tccaaaaaaa ggcgtaatct tttacatgat
    27181 ccaacaaaaa agtacacgta aaatgaccta ataacaaaac agcagacacc caagttagat
    27241 ttttatgcta acttttggtg tctgctccat tctttcacaa gttttttcat cctactttaa
    27301 atatattcat cgttgaataa acgtataagg tattttcact ttatcctttt tttctgtaag
    27361 aaacaattga aatgccattt ctccgcaagc ttccagatgg tggtcgatgg ttgggaaacc
    27421 aagaagctcg ctgatcagca aattatcgcg tccaatcacc actggtgtct tatcttgcag
    27481 atagctttgc aagatgcctg ctgcaaccat atccgaattt gtaaagacac catcaactcc
    27541 aagctcttta aaaaagaagc ctgcttgttt tcctttctct gcatctatac aatcccaaaa
    27601 aacaagtgat tcatcaaaag atggaaaaag ttgatgacat agctgcaaag tgatttttga
    27661 gttataactt agcctgccac ttcgccccaa cgtgatgccc aattgcttta taccttgctg
    27721 cttcaaataa gtaagacctt ctgtaattga ttgttctcga tcaataaaga cacagcttgc
    27781 ctgttttccc ttgatttctt cacaaaaaac tagaggtcca tatttttgat atgccaataa
    27841 atcatctagt gtattggcac gagacgtaat gatcaatcca tcgaaagctt tagctgcaaa
    27901 ttcttcaaga taccttcgct ctttttcttt atgatagccc gtcggtaaaa gtgtcacttt
    27961 gtaatcataa tcaaacgctg cttcaatgat cccactgatc aactgatcaa aatacggatg
    28021 attggtataa ggcagaatca ctccaatgct tttcgttttt ccataactta actgtctggc
    28081 atttgcatta gggatataat cgacttcttt catgaccgca agtatttctt tccttttttc
    28141 ctcatctaca tatggatgtc cattgattac acgtgaaata gtagaaactg aataacctgt
    28201 gagctttgcg atatctcgaa tgtttgccac tgctgcttcg ccacctatac aaaaagattt
    28261 tcttgtaaat agtctaccac agctggaccg cattcaaaaa actgatacat ttttccttca
    28321 tgcgaaaaac tgatccgctg cccgccccaa tatatatctt ttgtcaaatt ttcgatttca
    28381 ttcattggta tttcttttac tatattccta ttcaaccctt gaaaactgta caacgttaat
    28441 acggatccct tgaactcgac aaacgcataa aaataattgt tcgttgtgcc atctgttatc
    28501 tctacataag tattcattgc aagccctcct tttgatactt tgagtatagt gtatgaaacg
    28561 cgtctcatag caaggagttt gttttgccaa agaaaagttt tattcctctt tcattattac
    28621 caaagtctct tattttaaat tgaatacatt ataatgatac tgtaaatata tctttattat
    28681 tagtgaat
//
LOCUS       DAYNVV010000033        27914 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.033, whole genome shotgun sequence.
ACCESSION   DAYNVV010000033 DAYNVV010000000
VERSION     DAYNVV010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.033"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(18..716)
                     /locus_tag="ACGXWR_001622"
                     /pseudo
     CDS             complement(18..716)
                     /locus_tag="ACGXWR_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
     gene            795..971
                     /locus_tag="ACGXWR_001623"
                     /pseudo
     CDS             795..971
                     /locus_tag="ACGXWR_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(1147..1716)
                     /locus_tag="ACGXWR_001624"
     CDS             complement(1147..1716)
                     /locus_tag="ACGXWR_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFK0803194.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYKTLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1790..3079)
                     /locus_tag="ACGXWR_001625"
     CDS             complement(1790..3079)
                     /locus_tag="ACGXWR_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803195.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFYFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLIKVLYQEWLRYVI
                     GIHDRLIEEVRYYQETLEKFPNSKDKLYQFRLAIQQALAHPAVEWGMLLLKTLQERGY
                     LDVHPPEVKIVFFFRYEHQEARRLAGVLNKTLRHRKRISIHVCTRNKPPRYADLVITD
                     HFFPLDHNEDQKTYLYHPSFGIERLLTDINYWLGKNR"
     gene            3406..4281
                     /locus_tag="ACGXWR_001626"
     CDS             3406..4281
                     /locus_tag="ACGXWR_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFK0803196.1"
                     /translation="MGKRSTIQLMIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGT
                     FSRVQCTPDLLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLE
                     AMAENHATIDNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDD
                     ELLLLLDKFEKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAI
                     QLGISPRGSLSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKK
                     QIIHTLVAQIPIPVR"
     gene            4295..4618
                     /locus_tag="ACGXWR_001627"
     CDS             4295..4618
                     /locus_tag="ACGXWR_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803197.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KNKRF"
     gene            4615..5367
                     /locus_tag="ACGXWR_001628"
     CDS             4615..5367
                     /locus_tag="ACGXWR_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HFK0803198.1"
                     /translation="MILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKR
                     EISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKL
                     SAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPELLILG
                     NRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKD
                     RTAYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5357..7528
                     /locus_tag="ACGXWR_001629"
                     /pseudo
     CDS             5357..7528
                     /locus_tag="ACGXWR_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(7640..9811)
                     /gene="copB"
                     /locus_tag="ACGXWR_001630"
     CDS             complement(7640..9811)
                     /gene="copB"
                     /locus_tag="ACGXWR_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HFK0803199.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(9831..12017)
                     /locus_tag="ACGXWR_001631"
     CDS             complement(9831..12017)
                     /locus_tag="ACGXWR_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFK0803200.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(12017..12226)
                     /gene="copZ"
                     /locus_tag="ACGXWR_001632"
     CDS             complement(12017..12226)
                     /gene="copZ"
                     /locus_tag="ACGXWR_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HFK0803201.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(12239..12679)
                     /locus_tag="ACGXWR_001633"
     CDS             complement(12239..12679)
                     /locus_tag="ACGXWR_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HFK0803202.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(12753..13292)
                     /locus_tag="ACGXWR_001634"
     CDS             complement(12753..13292)
                     /locus_tag="ACGXWR_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HFK0803203.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            complement(13907..15373)
                     /locus_tag="ACGXWR_001635"
     CDS             complement(13907..15373)
                     /locus_tag="ACGXWR_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFK0803204.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(15684..17765)
                     /locus_tag="ACGXWR_001636"
     CDS             complement(15684..17765)
                     /locus_tag="ACGXWR_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFK0803205.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            complement(18289..18648)
                     /locus_tag="ACGXWR_001637"
     CDS             complement(18289..18648)
                     /locus_tag="ACGXWR_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HFK0803206.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(18678..19019)
                     /locus_tag="ACGXWR_001638"
     CDS             complement(18678..19019)
                     /locus_tag="ACGXWR_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803207.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            complement(19016..19690)
                     /locus_tag="ACGXWR_001639"
     CDS             complement(19016..19690)
                     /locus_tag="ACGXWR_001639"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFK0803208.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(20743..22041)
                     /gene="asnS"
                     /locus_tag="ACGXWR_001640"
     CDS             complement(20743..22041)
                     /gene="asnS"
                     /locus_tag="ACGXWR_001640"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HFK0803209.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(22081..23271)
                     /locus_tag="ACGXWR_001641"
     CDS             complement(22081..23271)
                     /locus_tag="ACGXWR_001641"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFK0803210.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(23292..23819)
                     /locus_tag="ACGXWR_001642"
     CDS             complement(23292..23819)
                     /locus_tag="ACGXWR_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HFK0803211.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(23866..26655)
                     /locus_tag="ACGXWR_001643"
     CDS             complement(23866..26655)
                     /locus_tag="ACGXWR_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HFK0803212.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(26802..27002)
                     /locus_tag="ACGXWR_001644"
     CDS             complement(26802..27002)
                     /locus_tag="ACGXWR_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFK0803213.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(27454..27774)
                     /locus_tag="ACGXWR_001645"
     CDS             complement(27454..27774)
                     /locus_tag="ACGXWR_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803214.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
BASE COUNT         7845 a         5918 c         4904 g         9247 t
ORIGIN      
        1 aaagaggggg ggatttttta tcgttgtgga atatttaaat accaacgctt gtcatgaaaa
       61 tcttgtgctc cacccttagt atttccttct ggatcgtttg tcgcacgcat catgacgtat
      121 actttcttat tagggaaatc acgcatattg aaagatacat gatagccaac atttcctaaa
      181 gtattataag cttgatttac gtctggtcta taaatcccat cagctcttac tctagctagt
      241 tcttttccag tattgtagtc cataatgaaa atatactcgt atttataatt agcaatgtgc
      301 catccagcta catgcaagtt tgcgttttcg atttctccga actgatcaat gtgggcgtaa
      361 tttgttccat ctgtcagcgt agaatttgca gcacctgctc gagttggatc aattactggt
      421 ttatcctccg aagtagttgg attatcatcc gtaaaaccat gagccaaatc ataggctagt
      481 ttttctttac ttacacccat ttcagaaaga taaccgtaag gatctgtatg atcgccccaa
      541 atattttgtg ttacccataa atgcgatttg attcctggtt ggttataagg agtgtctaat
      601 gttaatggaa taccatattt cattgctgaa tctcttgcca attcaacgta tactttatag
      661 ttcttttcaa aagtttcttt atcatgtgtg tgttgtaact cgatttgcac aggacttttg
      721 gctcacgagg ttgtcctact ctacatcttg ctgatagata tgctgaaagg aaaacaccaa
      781 cattatgttt tgctttttca gctagaacga gacaagcagg aataccttta gaagatatca
      841 aagatttttt aggtcataaa gatgtttcca ctacacaagt ctatgcccat atttctcccg
      901 aagtgaaaaa aagatcaatg aatcaactag aaaactatat agaagagcaa ataaaaaagc
      961 actcaaattg agtgcttttt taagctcact atcactaaaa ctatcactaa ttttatttat
     1021 aagcgaacat gtttctatca ctgatttttt aaatctagcg aaaaaccctt atcttaaagg
     1081 cgttcgttca attctttggc aaggtcttca aagcctggct tgcctagaag tgcgaacatg
     1141 gttttcttat agctcatgta gaaaaatttt cttgatgatg attttatcca tcaattgaga
     1201 ttgactgttt tgctctccta tgatttcagc tatgattgtc cgattttgcg gttttcttct
     1261 taactggtag ttgattttcc cagtttccat caactcgcta agcatatcca cgactccgcc
     1321 aaatccggtc tttttcgtaa taaaacctag tgctaccatt cgttcatcta gattttttgc
     1381 tgtaatcgtc acaccagtaa tgagcgagtg ctgtaatgtt tgggccagct cttccatccc
     1441 ttcagcattg gatacgacgg aagctgtttt gttaataggt tcttcgttta tttcttttgg
     1501 ttctttcctc tccactttca ctgtttgacg aaggacatct agttcttgca agagcgtttt
     1561 gtattgttct tgggtcagca tcacgccagc tactttttca cgattaaata tatatacgcc
     1621 agttcccgcg tctcgcgctt gagcaaatac atccatcggc gatcgtttca cttctgtgat
     1681 cgaagatgtg ggaacttcta atttctttaa ttccaatgga tttcctcctt tactaatcgc
     1741 tttttattat agcacagact gacttgtttt gatctttttt ccaaaggttt tatcggtttt
     1801 tgcctaacca gtaattgata tcggtaagaa gtctttcgat accaaatgaa ggatggtaca
     1861 gatacgtttt ttgatcttcg ttatggtcta gtggaaaaaa atgatcggtg atcactagat
     1921 ctgcataccg aggcggctta tttcgagtac atacatgtat agagatccgt tttcgatgtc
     1981 ttagcgtttt gttcagtacc ccagcaagtc ttcttgcttc ttggtgttca tagcgaaaaa
     2041 aaaagacgat tttcacttca ggagggtgga catctaaata ccctcgttcc tggagtgttt
     2101 tcagtaaaag catcccccac tctactgcgg ggtgtgcaag tgcttgttgg atcgctagcc
     2161 gaaattgata tagtttatct ttggaattgg gaaatttttc taatgtttcc tgataataac
     2221 gaacttcttc tatcagccgg tcatggatac caattacgta acgaagccat tcttggtaaa
     2281 gtacttttat cagctttgat ttgctttcgc tctcaaattc gctattcagc caaaacagcg
     2341 aatcaagctt ttcagtcaca atcgtcaatt tccgatagtc ttgtgtctct tctatccgtt
     2401 tccaccgctt ttcagtaatc tggttacagc tcaagcgcaa aattgctaga taattttttt
     2461 cttttattgg caaaatctgc tcctctctaa atagcaattc aggaaacaat tcaaagaata
     2521 gtgttcgact gtctcctaaa atctcgattt ctgccggatc ctttctttgc ttcaataatt
     2581 ggatgaacat ctcagaaaag gactgctctc catcatctgc aaaaaaatgc ggaaaatctt
     2641 tcaaaaagta aaacagcaga tatcttactt ttctttctga accaaagatc tgtgcttttt
     2701 tataagaaaa agaaaggtgg tactcgccaa accactttct caatcgctct tgcgtagaac
     2761 gatcgtactt ctgctcgtaa ggttcattta atagcagatt tttcagtaaa caaaacgggg
     2821 gtgattggat cagaaaaaca aacaagagat aaggttcgct atatccttga tcataaacta
     2881 actgaacggt tttcttatga agaatcagct gaatgggaca gtcgctttcc gccaaacgtt
     2941 tcagatgccg atccactgtt ttaacatcga ttttcagttc ttcagctaaa tcagcttttc
     3001 gccagatcaa atctttcatt agattgatta gtgaaaataa attctgtgca ttttttgata
     3061 atagtttttg ccatctcatc gatcatttct cacctgattt ctaaacatat tgtttgatca
     3121 aaatgagttc actcctaaaa agataaaaaa ctccctttct atttatttaa atacgcaaat
     3181 cttcctcatt attttttatt ttactcaatt taatcgtatt ctcatttcaa aacgaatgta
     3241 ctttaaaaaa acataataag atcactttgc ttgtaggatg tattcccttc cattacaatg
     3301 aaataaatag cgattttatg agaaggtgat gtgaaaatgg aagaaaaaat agaagaatcc
     3361 aaacaaaaaa tcgatcagtt gatataagaa ttagaaaaag cggtcatcgg caaacgttca
     3421 actatccaat tgatgatcgt ggccctatta gcaggtggtc atgtcttatt cgaagatatt
     3481 cccggtgtag gtaaaacgtt actggtcaaa gcactagcaa aagctgtaca gggaaccttc
     3541 agcagagtcc aatgtactcc tgatctgctg cctagtgata ttcttggttt ttccgtatac
     3601 aattcacaat caaaagagtt tgaatttcgt ccgggaccga tctttaccac gatcttgttg
     3661 gcagatgaga tcaatcgtac gactcctcgt actcagtcag cacttttaga agcaatggcc
     3721 gagaatcatg caacgatcga caacaataca taccctctag acaatcattt ttttgtctta
     3781 gctacgcaaa atccaatcga gtacgaagga acatatcctt tgccggaagc acagctcgat
     3841 cgttttttat tccgactaca aatcggttat ccttcttttg atgacgaact tttgctactt
     3901 ttggataaat tcgaaaaagt gttggataac ttaaatgaag tattgaacag ttatgaaata
     3961 gaagaaataa aaacaaatgt ggcgaatgtc tttgtcagtc ccgaagtggc atcttatgcc
     4021 ttgcagttag tgtcagcaac aagaagtcat gctgccatcc agcttggcat cagtccacga
     4081 ggaagccttt cctttattca ggcagcaaaa gcttatgctt taatccatgg gagaaattac
     4141 gtcacgccca aagatttgca ggatttagtt ccttacgtgt tttcccatcg cctgattttt
     4201 tacgatcgtt cattgaagga agacgaaaag aaacaaatca ttcatactct tgttgcacaa
     4261 attcctattc ctgtgaggta gattgaggta gacaatggaa aaaatcaaag attatttcat
     4321 taattttgtg ttatttctgg tatatttcat cattgtgctt tttgctcttg tattcaacaa
     4381 ttctttaggc tggttcttgt tggccttttt tactctttat gtatcatgga gcttgatttc
     4441 attaagcagc tttctaaaga aactttcggt tacttgtaca ttgcagccac tcgtttatcg
     4501 caaaaaaagt atgcaggtta ttttttccat agcaaaaaag agaacttttt ctttacctct
     4561 ccctcgttta caaatcggct tcccagcaat ctttgcagaa aaaaacaaga gattttgatt
     4621 cttacaaata aaccgcaaga agtccaattg ctttggcagc caaaagaaag aggatgccat
     4681 gaaacattaa ctgtcatttt tacagcctat gatagtctag gacttttcag aaaaagtgca
     4741 aaaagagaga tctcttttcc tgtgactgtt ctgcctgctt tttgtaagat tcaagcagaa
     4801 aaattacaga gagttctgga aaaaaaacag cagctgaacg cgtaccaaag aggtcttgat
     4861 tttcgggaac atcgcgctta tcgtccaggt gattctttca accgaatcga ttggaaattg
     4921 tctgctcata ctcaagagtg gttataccgt gaatacgatt atcaagaaga agaatgttct
     4981 cctctttttt gcttttgggg ttcgcccagt ccaaaatttg aacctctgct agacttgtat
     5041 ttttctttat ggcatttgag aaaagaaaag cagccggaac ttctgatatt aggcaaccgc
     5101 gcctttcatg gcaaagaccc cggtcatacc tattttgctt ctttggaagc tggcgatgag
     5161 aaagcttttt tcgcacactt gaaaaaatat gcaaaaaaac aaatcgtcct ctttgttcct
     5221 gagaattctc ctgaagtctc agaagctatt gaaacattgt caaaagatcg aacggcttat
     5281 cttgtttatt tcgtagaaaa acaactcatg gtccaagaaa aagacaagat atgttcattg
     5341 ccaggaggtg aatggattga cgattaaacg ggaaaaatgg ctgcgtggcg tttactcctt
     5401 tgtgatacta agtgtaggtg ctccgatatt tgtagtagct aatcaattgc aaaacagcta
     5461 ccttcttatc ctaactattg gtgtcctatg ccttattgtc tgctgtattc ctaaaaaatg
     5521 ggtacgtttg ctgctttctt tgccagtaat gataggttgt ttgtttttat attttccttc
     5581 gaagacattt tccatattat ggatcttaca gtttttttcg tcagttacag aggaattctt
     5641 ccatctatcc caaggtaaac tttattattt gccagaaaag acagcttttt ttctcataat
     5701 gttgctgatc tatttattta ttacattgac cgtggattac gactattggt acgcaccctt
     5761 tctttctttg atggcttact tcatgatgct taccgttttt cggaaaaaag atttactgta
     5821 cgaaatgatt gcggtagtaa ctgttttgtt cgtgtatctg gcagcaaggc aatttttctc
     5881 catccggttg ttgtcgggaa acactcgatt ccagtcattg actacagttc tgcttatttg
     5941 tttcttaact tttagcgcta tcttgccttt atatcttccg aaagtacacc aatctctcga
     6001 ggaaacgagt gaaccgatcc gagaatatct taatgatgaa gggctttatg acacactcca
     6061 tgagtatcaa ttaaccggaa gtgcaagaac aggcttcagt gagaatgatg aacagcttgg
     6121 tggaccttta tatgataatg gcgaagttgt ttttacagcg aaccaaaaag gaaatggcta
     6181 ttggaagatc gaaaataaaa atcattacac cggttctgga tggatagaag atcaggacgc
     6241 acccatccaa ccaatccaag aattccctgt tgacatcacg agctaccaaa ccgttataga
     6301 agacaaagaa aacattacat tgaccctaaa aaaacaagct ttcttacctt atccttatgg
     6361 aaatactacc ttgactgatt tttcattagc tagtggacaa acgctttact atttgcctga
     6421 aagccagcga ttcattcctg tcccgaatga atcgacacgt tctgcaactt tacaaacaga
     6481 aaggttagtt tttacgagag aagaattaaa aagcagtcag ttaaaagctg atgatttaga
     6541 aaatcagcag acaaatcttc aattgccaaa aagtttgcct aaacgtattg aggacttggc
     6601 ggtcgaattg accaaaaatg aagcaacttt aattcgtaaa gtcgaagctg tctaacagta
     6661 tttaaaaaca agcggaaatt tccgctattc caaaacggat accgggcata ctccgaaaga
     6721 acacgattat gtggattatt tcctctttga ttcaaaagtc ggctattgtg acaacttttc
     6781 aacttctatg gtcgtccttc ttcgaacact tggtatccca gctcgctgga caaaaggttt
     6841 tacaaatggg ctcagaacag gcacagataa tcaagggaat gaggaataca gcattctcaa
     6901 tagtcatgct cattcttggc cagaggtata ctttcctgga tttggctggc ttccatttga
     6961 accaacccct tcatttgcca atccaatggg ttcacaacca gttgctgaaa caaccgaaac
     7021 cgtccagcct gctatcgaac aaccaaatga aagcgaaaat atggcagaaa ctatttccag
     7081 tgagagatct gaggtcattc catcagaaga aacaacactc acaccagctt ataaaatcgt
     7141 cttattcagc cttggagtgt gtttatccgt cttgttgttc tttctattgt tattcagaaa
     7201 atctctgcgc tggacaagtt atcttatcta tcttcatttt tttgcttcta ctaatacgat
     7261 tgcatatcaa aaacttctta accctttgga aacattggta ccgcgcaaac ccgcagaatc
     7321 tttgcaggaa tatagcctgc gaatagaaca agaattcaag ctagatctgc gtttcattcg
     7381 attaactact caatatgaag cagaaatata tggacgacaa gcagatccgg taaaattcga
     7441 taaaaaaacc tatttagaaa taacgcgtat aataagaaaa acggtataca aaaaaattct
     7501 gacaaaaggg agccgcttca aaaaataaga taaaatttct ggagaatcta cttctggaat
     7561 gccgagaacc agctgattga gtatcgatta ctcgaaaaaa aggttgtgac acgttttttg
     7621 tcacaacctt ttttcattat tatttgattt tcaatgtcaa agcatttaga gctacaacta
     7681 ccgtacttaa cgacatcaag acagcaccaa ctgctggact taatatgata ccaattggcg
     7741 caagaattcc ggctgctagc ggaattgcaa gaatattgta acctgccccc caccagaggt
     7801 tctggatcat tttctttcgc gtttgcttgg ctagatcaag aaaatgcaaa atatcttttg
     7861 gatcgctgtt tgtcaatacg acatccgcag aatcgattgc gatatctgtc cctgcaccga
     7921 ttgccatccc gattgaagca cgggctaaac ttggcgcatc attgatccca tcacccacca
     7981 tgattacttt tttcccttgg tcaaggtatt tctggacaac agcttcttta tcatctggta
     8041 ataaaccgcc ataatattct tcgatcccta aataatctgc tactgcttgg gcagcgtttt
     8101 tattgtcacc agtaagcatg acaggagtga tttttctttc tttcaatgtt cggataaatt
     8161 cttttgcttc tgtttttact acgtcaccta aagcaacgat tgcagctaga tgattttcta
     8221 aaatcaggaa gctgatggta tttccttgtt cttggtaagg tttcaataat gcttgttcta
     8281 cgtttaatcc gagacgctca acttcttttt cattaactat tttcacttgt tgttttttga
     8341 ctgttgcctc tagcccgact cctgaaagat tttttagatt ttcagcttga taaggcttga
     8401 tttcatgttc tttcaaataa ttcataatgc caacagccaa tggatgattg gcattcgctt
     8461 ccaaggctcc tagatattga aggatttcat ttttattgaa cgcatcatca agtacttcga
     8521 cacccgttac agtaaatttt ccttctgtta gtgttcctgt tttgtccagc atgatcacat
     8581 ctagatcatt ggcttgctcc agtgcattgc ggtttttcaa aagtaatccg tttttagctg
     8641 ctattgatgt ggagcgagca acaactaatg ggatagctaa acctagagca tgaggacagg
     8701 cgatgataaa gactgttacc atacgttcta atgcattagg aagatctgtc aagaacaacc
     8761 aggcgatgaa tgccaggata cccacaatta atgcgacata aaacagccat tttgccactt
     8821 tgtcagataa tgactctagc ttggattttt ctccttgtgc ttttcgcacc atttccataa
     8881 ccttcgctag ataaccattt tcaccagttc cagttacttc gatttcgatc gttccatccc
     8941 cattgataga accgccaatc actttgtcat tggcttgttt tttgattcct cttgattcgc
     9001 cagtcacagc tgattcgtca acaattgttt cacctttcaa gattacacca tctgttggca
     9061 ttttatcacc agaccggacg atcaaacgat caccttcgtt tacttctttc aatgaaactg
     9121 tctcttcttt tccatctttc gtcaagcgtt tcactgattc tggcagtaat tctgctagtt
     9181 tttgtaaagc attgctggca ttcgacacag cattcatttc aatccagtga cctagtagca
     9241 taataacgat caaagtagcc aattcccaga agaaatccat gacgtgtgta tgtggattga
     9301 gcagatttgc gataaacgaa tagacactat aaatatatgc aactgtaatc cccatcgcga
     9361 tcagtgtcat catagcagga cttttttgtt tcaattccat cttagctcca cttaaaaatg
     9421 gctgaccgcc atagataaat agtatagttg ctaagatcaa tacgagccaa tcagaaccag
     9481 gaaacgttac ttgaaatgga aattccattc ccatcattgg tgaaaaaaga atgattggga
     9541 tagctaggat aagcgatagc caaaattttt gtttgaaatt ccccatgtgc atggaatgat
     9601 ccatgccgcc gtgttcgtga tccatgtgca tcgaatggtc catttgtttg ctgtttgcta
     9661 tatctccatg gttatgtccc atgtgcatgg aatgatccat ctgactatgg tcatgtttca
     9721 tctccatctg tttttcatga gattctgtac tttctttgtt tactacttct tttttatgct
     9781 catgtttttt ctccatatcg ttcccattca tttttactcc atcccttctc ttactttttc
     9841 atgtgtcgat ttaagctcag ggagttcaac aatacactga cggaactaaa cgccatcgct
     9901 cctcctgcaa tgattggatt caaaaagcct agtgcggcaa aaggaatacc aatcgtatta
     9961 tagacaaaag cccagaaaag attttgtttg atttttctca atgtcaacct agacaactcg
    10021 attgtttgtg caatggatgc caaactgcta ttcatcagcg tcacatcggc tgtttccatc
    10081 gcaatgtccg ttccacttcc cattgccata ccgacatcag ctaatgctaa ggccggtgca
    10141 tcattgattc catcgcctgc cataccgact tttttgccat ctttctgaag tttttctacg
    10201 taggctgctt tatcctctgg aagtacttca gcaaagatat gctttggatc aataccaact
    10261 tgtttaccaa tcgtttcggc tgccagtttg ttgtctcctg tcagcataaa aacatctaat
    10321 cctttattct ggagctgctt gattgcttgt ttggcttcta gtttgatttg atcagccacg
    10381 gcaatccacc cgatcacttg cttttcatca gctaaaaaca tgactgtttt tccctgctgt
    10441 tctaattcta acgcgtgttc ttggtattca tcaaatgata ggttcaattc aattaatcgt
    10501 ttacgtgtac ccgcaaaata gcgtactcca ttaatcgtac cgctgatccc agcacctggg
    10561 tgggctgtaa aatcaatcat atcgtatgtt gctgcttctt gcagttttcc gtattccacg
    10621 attgctttac ctagtggatg ttcagaagct tgttctaaag tataaaaaat agataggact
    10681 tcttttgaac cgactagatc tgtaactttg ggctttcctt ctgtaatcgt tccagtttta
    10741 tccaaaacaa tgctgtctaa gtgagcagct gcttctaatg cttctccgcc tttaattaaa
    10801 attccatttc gtgcaccaac acccgttcct accataatag ctgttggggt cgctaaacct
    10861 aatgcacatg gacacgcaat gactaataca gagacactat ggatcaatgc gagttgccaa
    10921 tcaccagtga tcaaacctgt agctatgagc gtgataaacg cgatgactaa tacgatcgga
    10981 acaaaaatcc ctgagatccg atctgcgatt ttttggattg gggctttgct cccttgagca
    11041 tcttccacca tttgaatgat ttgcgctaat actgtctgct tgccgacttg tgtgacttcc
    11101 atgtgtagca gaccattcgt attgattgtc ccgccaaaaa gcgtgtcatc cggattcttt
    11161 tctacaggaa gattttcacc agtaagcata ctttcatcta tcgcactgct tcctgaaata
    11221 attcgaccat ctgctggaat ctgctcacca ggacggatga ctagttgatc accaacgact
    11281 acttcttcaa tcgctaacgt ttcttctttc ccgtttctta tcacttgggc ggtttttgtt
    11341 tgaagagaca tcaattgttt gattgcatta cctgttttcg tttttgctgt atgttccaaa
    11401 tatttgccga gcaaaatcag cgtgatgatc atactgctgc tttcaaaata aagatcttgg
    11461 gggtgtccac ggaaaaatcc gttgtaaatg ctcaatgcaa aggcagccga tgttccaatt
    11521 gctaccaata catccatatt tggtgctttc gtcttgattg catggtacgc acctttataa
    11581 aaacgagcac cgacataaaa ttggacagga gcagacagca ctaactggac gattggaaaa
    11641 tgaaaaaagt gaacaatcgc cgcatggctt cctaacatca tagcaatcat tgacaacatc
    11701 aacggcaaag tcaaaaccgt actcaatata agatcgaata gcattttttt caaatacgct
    11761 tgcttttctt ctgcaatttt ttgtttgtgg gcttcatcgt acaaaattgc accataaccg
    11821 atgttttcta cgctttggat taatttttca gtggtcgtcc cttcatattt gacacttgct
    11881 ttttcagtgg ccaagttgac tgtggcattg accacaccag gttgtccgtt cagctctttt
    11941 tcgatcctag cagaacaatt tgcacaagtc atacctgtaa tgacgaacgt atccattttg
    12001 gtttctgctg ttgccatcaa atcacctctg ctttataacc caatccattg attgcttgac
    12061 aaatcttttc ggattgaact tttgtttcat caaacttgac cgtaccgttt gcttttttca
    12121 aatttacttt cactttttgc acgccgtcaa gtgcgcttac tgtttcttct actcttgctg
    12181 cacaatgatt gcagctcata ccttcgattg aaaattgttg tttcattttt tcttcctcct
    12241 attgatgttg tttacattca cattgacctg ggatacagtt acattcgatc gtatctactg
    12301 gttgcttttg ttccagttgt ttcaaaatct cattgatatc ttcttgagtc aaagtggctt
    12361 cttctactag atccgcaatc gtctctccaa tcctttttgc acagatatgg gaaaaaagat
    12421 tttccgtcgc actgcgaact gtttccatct ccgagacagc tggatgataa atgaattttt
    12481 ttccttcttg ttctgtccag atcacttctt tttttaccaa acgtcccagc aaagttttga
    12541 tcgttgctgg tttccaatcc atcgaatcag ctaagatctg cgtgatttct tgggctgtcg
    12601 tctgtccaag tgtccaaata acacgcatga tctcccactc tgaatcactg atctttactg
    12661 gcgttttgac tttttccatt tatttcacac ctttcgttta caaatgtaat cattagctta
    12721 tgaatacaga ttacgcttgt aaacaaaaac tgtcaattat ttttgctctc tattttcaat
    12781 ttagttaaaa attcttgttt ctctcgtctt gttttaagga tgatcagttt atttcttgca
    12841 ttagctactt ggatcagctg ctgtattttc ggttcattgt tttcttcaaa atgccagata
    12901 aaagataaaa attctaagta ttccctgttt agtttctctg aaaatgattc aggcatatct
    12961 ggccgagatt ttttgtttat ctttcttttt agagaacgcc aaactactcg gtagatggcg
    13021 agataacgcg gcactttaag ccaaatgatc ttatctgctt ctttaatcct ttcctctaat
    13081 gtagaagtat aatttccttc aacaatccat gacggattag ataccataaa cgattgctgt
    13141 tcttgcaaaa accacttttt tgcctgaata ctgtagtctg ttgtatgcca taaaaggtct
    13201 agcggcagta gcggaaagtc ggtgatttct ttgatcttcc ttgcgagggt cgattttccc
    13261 gacccacttt gtccaatcac gatgatcttc attcttctcc ctcacttctc tttggaattt
    13321 ggttcgatca taccacttat aacgccgcaa aaaaacaagg gactgtgaca aaagtcgtgt
    13381 caaagtccct tgtttcgaat aaatggtgtt caatcagctg accttcagca ttaactcaaa
    13441 aaacggcaaa atatgaggag ctattttttc gtttgttcct ctaatactca ggtcaaatcg
    13501 ctgattttac aacctcttcc ttaaacggtg ttctcctgcc aacacctcgg tcacaaggca
    13561 caatagtcaa caaacatgag aagttgtttt ttgaaattgc tccttgtgac tcggagttaa
    13621 acggcaggct cactacctct ttcttaaacg gtgttcaaaa gcttgcatct gcggtaataa
    13681 gcccagcaaa acgaaaaata tgaggggcta tttttgtttg gctgttctta ttacttgatg
    13741 caggacagct ttttcacaac ctctgattca cggtgttcca gaagtagctt ctgcgaaaaa
    13801 caagccgaaa cttcacaaaa atttgagaag caattttcgt aaattccttc ttatttcttg
    13861 aagctgacca cttctgtcac aacctcttgt aacaagtatt tctattttaa ggctgaacca
    13921 ctgtttctgg ttcagtgatt tctttgtttt tgtctcgacg agcaattgct ggcaagatca
    13981 tacctaataa gatcaagaca attggtgtga tgatattcgt gaataattgg aaccaccatg
    14041 ctttaggatc agcagtataa tctacttttg gcaccattcc taggatacat gcaaacgcag
    14101 tgaaggcaaa gcaccaagca ccaaagataa aaccgatttt tggattttta acaaatttat
    14161 attcagaatt gaatttctta taagctttat tcaacatcat atatgccaag aacacccata
    14221 ggtaacgcat tggcatgaca actgagttca agttcgtcaa ccattttact aattcattca
    14281 tatctttgat accaaagatc ggcaacaaaa taatgattcc tactagtata cctgtcagaa
    14341 gataaccatt caccaatgta cctttacgat tacgtttacg tagccagttt ggtacaaatt
    14401 ctggatccgc atctgctaac aagattttta gtggtgcatc aattgaaaag gctaatgcgg
    14461 agatttgtcc aatcatgttt gtcaatgcgt aaatgatcat caatgagtta ccgataccat
    14521 agtaattacc taaaatttga aaagcactgt atgccccatt tgccatcaag tctttaggaa
    14581 tattatcgct agcaaacagc atacccattg cgactgagcc taatacagca caaatcccta
    14641 ccattgctgc taagaagatc atccctttag gaaattcctt tgcaggattt cttgtagagt
    14701 tgacataagg ggatattttt tccgctcctc caactgcaaa tactagcatc gaaacggttg
    14761 tgaaataact gaaatcaaat gttggaatat atgttttcac ttgattcata tgtggtgtgg
    14821 caaattccat cgttggattg atgaacggtg ccgttacagc taaaagaata aataagatcg
    14881 acatgacgaa catcgctgtt ccggccagtc cgccaatcac tttcaaagta gaaagtcctt
    14941 ttgttgataa atataaaaag gcaagaaata taataagtga aataactgct accatttgta
    15001 ctgacatcgt atttacgata tttccatttc cttggactgc ccaaccgcca gcaatcagga
    15061 ttgcttgagg cttttgtgcc aaataaggaa tatggacgac ccagtaagtc caagcggcat
    15121 agtatgccag tcgtttatta gatgtcgtat tttcgaccca tgaactgacg cctcctttac
    15181 tatccttgaa ggctgaccct aattgtccaa cgatcaatgc gtatggaata aaataaatgg
    15241 ccaaaatcaa tagccaagag gtgacaactg atactccttg ctgagcatag ttattaacta
    15301 cattccccat gccccaaacc atgttaaatg caattaacgc aacagtaaac cagcgtaatt
    15361 gtttgttgtt cattcgttct ctcctttatg ataaaaattt gttatccaga tgtaatcata
    15421 ttcaattttt aacaaactta caagacagtg ttattttatg tgtgtattct tttatttaat
    15481 acacatcgtt ttttcatatt ttttccatca aaaaaataag ttattttctt ttatttcatt
    15541 taccttattg aatttcaagc tattttgaat tttctgcaaa attaaaaaca ttagttattt
    15601 tataatccta tctattttct ttacattttt cattaagaaa aggatataaa aaaaagagga
    15661 cgttcattcg tcctcttcat tgatcaacgt ttatttttta catgcaagct tcgcatggca
    15721 ttcaaaacag ctaatactgt caccccaaca tctgcaaata ctgcatctcc cattgatgca
    15781 aaaccaaaag cacctaaggc aagtaccaaa atttttatcc caatagcaaa gacaatgttc
    15841 tgtttgacga ttttcaatgt tttctttgct aaatggattg cttctgcaat cttcgatggt
    15901 tgatcattca tgatgactac atctgctgct tcaattgcag catcgcttcc caatccaccc
    15961 attgcgattc ctacatctgc tcttgctagc accggtgcat cgttgattcc atctccgaca
    16021 aatgcggtct ttttattgtt tctttgtaag atttcctcta accgctgcac tttatcttct
    16081 ggaagcaatt cgctatatat cttgtccacg cctacttgct tcccgatatg atcagcaatt
    16141 tttttcgaat cgcccgtcaa catgactgtg ttcttcacac cagccttttt taattgaacc
    16201 aatgcgtcta cggcatcttc tttcaaggta tctgcaataa caagataacc actgtaactt
    16261 tgatcgatcg ctagataaag caatgtaccg atttcttgac ttgaaggaaa agagatttca
    16321 aatctttcca tcaatttgtg attacctgct aatacttgtt tgccatcaac ttcagctaag
    16381 atcccttcac ctgcaaattc ttggatatta gctgttggta aaagcggacc tgcgtagcct
    16441 tctaaaacag attgagcaat cggatgtgta gaaaactgtt ctgcactcgc aacatattgc
    16501 atgaatatct ttggatcgat ttttgtatcg atcgtctgga tcgaaaagtc acctttcgtt
    16561 aatgtgccgg ttttatcgaa taccactgtc tcagtttgtg caagcaactc caagtaattt
    16621 gaacctttta ctaatacacc gattttactt gctcctccga taccgccaaa gaaactaagg
    16681 ggtacggaga tcactaatgc acatggacat gagatcacta aaaatgtcaa tgctcgatag
    16741 atccattcag aaaacgccgc tccagaaaca acaagtggag gtaaaacagc taataaaacg
    16801 gccaatccta caacgactgg tgtgtaatag cgcgcgaatt tagtaatgaa attttcagct
    16861 ggtgcttttt tactgctggc attttctact aattctaata atttgctgat agtagaattt
    16921 tcataagatt tttctacttg aactaaaaat ggtttatttt tattgataaa tccacttaat
    16981 actgtttcac caacatatac agatttaggg actgattctc ctgtaagtgc tgacgtatcg
    17041 actaatgatt ctccttcgat gatcgttcca tctaacggta cacgttcacc aggcttcaca
    17101 agtacaaact gaccgatctg cacgtcttca gggttcacgg tcatcaatcc ttccgtcgtc
    17161 tgcacgtgag ctgtttctgg acggatcgcc atcaattcgc gaatcgattt tcttgaatga
    17221 ctgactgcca atccttggaa atactcgccg atttgataaa atagcatcac tgctacggct
    17281 tctggatatt caccgatcaa catagcgcca atcgtagcaa cagacataag aaaattctca
    17341 tcaaagattt ttcctttgac gatattcatc actgccttct tcactacatc atatcctatc
    17401 agcagataaa tcaataaata ccctatcaag cgaattggtt cattaaaatc aaataatagc
    17461 aataaagcga tacctgcaag ggaaaataaa atccggaaca gcgtatttct ctctttttca
    17521 tttccatgtt cagatacttt ttccttatct atttctgtta ctttgacatc tggttctaat
    17581 tccttcacta ctttttttat ttcttgttca atcgtagcca aatgatcttc ctctgcgtca
    17641 atcgttagtt ttccagaagt gaagtttacc gttgcttcct tgactccatt gatcttctga
    17701 actccttttt cgattttcat tgcacagttc gcacaatcta aaccttctaa tctgtaactt
    17761 ttcattttaa tgacctcctc gcctcaacat atgaatatct cttcataact aattataaat
    17821 gaacggttat tcatatgtca aggtatccga aagaaaaaat gaaaaacatc tgcatcggaa
    17881 aatttcttcc atacagatgt tttggcttat tctttctttt tcttttcgat cattgccact
    17941 gctcttatcc aacccgcact tgccttcttg atcttgacag gatagcaact aagtttgaag
    18001 cctgttgctg gcaatttgtc taaattcatt aatttttcga taggacaata tcttttttca
    18061 atccctgcaa aatgtccttc ccagatattc gaagctccac tacgctttca aaaatataga
    18121 aagagttctt taatgaaaat tatttcaact ttccataaac agtaacccca tataaataaa
    18181 agacgtaaaa gtcacatgga agaacttata caggagaacg catagagtca ggtgaaatac
    18241 atgtatccca cctgactcta tgctttatct aacctttatt attctctttt atacaatttc
    18301 tgcaccgaat ggcatcaacg ccaatcgagc aagtttgaaa gattgcttgg caaaaggtat
    18361 ccctatgatc gtgatacata gaaggatgcc gctgacgaca tgtgcgagag caattggtag
    18421 gcctgaaacg atcagccaga tgatattaac aatcaatgac atgccagact ggtgataaat
    18481 tacttctttg ccaaaaggcg caaaagaaag ggaggcgatc ttaaaacatt gcataccgat
    18541 tgggatacct atgatcgtga tacaccaaag tatccccgct gctaaccagc taagaccacc
    18601 gattagtccg ccgaatataa accagatgac atttcctaaa caactcattg tatttctcct
    18661 tctattactg tttttgatta aaactgggca aaaaatgatt ttattcttct ttttttagct
    18721 tccagtatca aatattctgc aaattttttt tggatttctt ccgtattttc ttttgttact
    18781 aatgtgtgtt ggattagttt tcctgatggt cgctgatcca atcgttcttc tgactgttgc
    18841 acgtccgctt gcgcaaatcc gataatccgt ttttcttttg ttacagcaac gagcaatagt
    18901 ttattcttat catttaggtc agctgccgtt tttgctttta cgaatgattc tggatgatca
    18961 gtaatcagct gattgatttg aggtagatct tcttttactg cccaccgtat ttccatcatt
    19021 tctcactttt ctttcgctca tttttatctc cactaaaaaa atcgactgcg gcaattgcat
    19081 ctatccagct ttgtgcaatg atctcatgtc cgccaatcgt tgggtggacc ccatcttctc
    19141 ttgtatattt cgaaaaacca taaacaatcc ctaaagcatt gaatatacca tctaaaggaa
    19201 ccagcaatgc gccatattcc ttagcaagtt tacgaacaat ttggatttta gggtctaagt
    19261 ctttacgcca gccatgacgg tcgtcggtta taggaagtac aaacggctcc atcaagatga
    19321 tgttgcagat tcccactgtt tgaagttcat ttagtaattt tcgataaacg gattcaaatt
    19381 gctgagcaga tttctcagtt ccgaatatag cctgatcgct agtattatgc caggtatcat
    19441 tgattccgat caaaatcgat acatagtcag gttgtaaagc taaacaatct tcttgccagc
    19501 gtacttgcag atctgcaatt ttgtctcctc ctatcccacg gttcatgcat tcaaattcca
    19561 tcgttggata ttgggagatt agttttccgg caatcaaaag tggataacct ttacctagat
    19621 cagttgcttc tgctcggtct cttcctgcgt ctgtaatgct atcaccgata aataatatac
    19681 gttttttcat ttgtcaaaaa ctcctttttg aataaaacga tgattttctt ccttatatta
    19741 tcccataagc cctatcaaga cgaaagagaa aatatatgta taaaaaatga caccagccta
    19801 gtcccttcaa acaattgaat gaacgctcat caagtgtcta gttttttatg ctattttttt
    19861 cttaacgtgc cggattcccc ttgattcctt cgttgtttgg tccagagaga tcgatcacac
    19921 ctaagcttcc gtcaatcaga ccactgatga cgccatcaga acatatattt ataggctcat
    19981 ctaagacttc tagtaaatgt ccctttacta atatctcttc tagattgctt gggatagatt
    20041 ggtcataact ttatctggtc cgatgatttc aagggtgaat tgaacttaca tatggattat
    20101 tgcatgctga aaatacggac ctactccatc ttcgaatgtt actattagtt tgttttcagg
    20161 tgctagatgc tgctttattt caacagcaga agcatcatca aatcagattt ccatttgaat
    20221 taccttcttt gtaaatgttt gattgattgc gatttcgtta tagaaccttg tgaatcaaat
    20281 agcaatttct tttgctttct tctcttgtct gctggaaact tcctttatcc cgtattttaa
    20341 aaaaagaact gcgagagttc gcagttcttt tttagaataa acggtgctct ccggccaact
    20401 cctcggtcac aagtcacaat agtcatcaaa catgaaaaac tgttttttga aattactcct
    20461 tgtgactcgg agctgaacgg caggcgcaca acctcttcct taaacggtgt tcaaaagcca
    20521 gtttctcggt attaagccaa atttatgcaa aaatgtggaa agccatttcc acaaaatttt
    20581 tcttaatact cgaaactaaa cagctttttc acaacctctc cactaaacgg tattcaaaag
    20641 cttacatctg cggtaataag tcccgccaat tcaaaaacat gaacagctgt ttttgcttgg
    20701 ctgttctaat tacttgatgc agaacagctt tttcatcacc tcttatggat aaattcggtt
    20761 caacaaacgt gggaatggaa tagcttcacg tacatggtcg ataccagcaa tccaagtgac
    20821 tgttcgttca agacctagac caaaaccaga gtgcggaaca gaaccgtatt tacgtagatc
    20881 aagataccat gaatattctt tttcatccaa accgtgatta cggatttgtt ctagcaagaa
    20941 atcatagtct gttgcccgtt cgcttccgcc aataatttca ccgtaacctt ctggtgcgat
    21001 catatctgca cagatcacca cgtcttctct tgttggatgt ggtttcatgt agaatggctt
    21061 gatggctttt ggatagttta ggataaagac aggctgttcg aatgaattcg caatgaacgt
    21121 ttcatgaggt gaaccaaagt cttcgcccca ttcgatgtca tcaaatccat ttttcttcag
    21181 taattcgatc gcatcatcat aagtaatacg agggaatggc aattttgtat aagtttttaa
    21241 gacttctttg tctcgtccta gtacatctaa tgcatattcg caatgatcta aaacattttg
    21301 tactaagaat gctacatatt gttcctgtac ttctaaactt tcttcttgat gagtgaaagc
    21361 catttctggt tcgatcatcc agaattcgat caaatgacgt cgtgtttttg atttttcagc
    21421 acggaaagtc ggaccgaatg aaaagacttt tccgaaagcc atagcagcag cttccatgta
    21481 taattggcca ctttgagata aataagcttt ttgatcaaag taatttgttt cgaatagatc
    21541 cgtagtgcct tctggtgcag aaccagtcaa gatcggcgga tcaattttga caaaatgatg
    21601 ttgattaaag aattcatacg ttgcacgaat gatttcattt ctgatctgca taatcgcatg
    21661 ttgtcttgaa gaacgcagcc ataaatgacg atgatccatc aagaagtctg ttccgtgttc
    21721 ttttggtgtg atcggataat cgtggctctc gcttaccact tccacatttg taattccgat
    21781 ttcataacca aattttgaac gactgtcttc acggatttct ccagttacta acacggatgt
    21841 ttcttggtgt agatttttag ctgtttggaa aacttcttcc gacacttcgc tttttacaac
    21901 tacaccttgg aaaaaggctg ttccgtctct taattgtaaa aatgcgattt ttccgcttga
    21961 tcgcttattt gcgacccaag cgccgattgt tactgtttct cccacatggt ttttcgaatc
    22021 gatgatttga atttgttcca cgtatgactc tccttttata ttccttgaat ttctttagga
    22081 ttaattttga cttttactct caataaattg cttgattctg cgtaccgctt cttctaacgt
    22141 agcgcgatca gtagcataac tcatgcggac attttctggt gccccaaagc cttcgccagt
    22201 cacaagcgct acccctgttt cttctaaaag atcttctacc cattgtgtga cattttcata
    22261 tttacacatg cgtagcgttt cttttacatt aggaaaaaga taaaaagctc cttgtggctt
    22321 ttcaagagaa acacccggca gttctgccac aagcgaatat aacgtattca ggcgttcttc
    22381 aaaggcgttc cgcatttctt ccactgtatc ttgctcgcct ttcaatgctt caacagctgc
    22441 atattgactg actgctgtcg gattactggt tgactgggaa gcaacagcga tcattccatt
    22501 gatgatcaca ggatttccca ccgcataacc aatgcgccag cctgtcatcg catatgtttt
    22561 agacacgccg ttgatgatga tagtctgatt tttgattgct tctgaaatcg ttgcaattgg
    22621 agtaaactca ttgccattat aaactaaacg accataaata tcatcagcaa ctatcaaaat
    22681 atcatttttt actgcccatt caccgattgc ctgcagttca ttcttgctat aaatcattcc
    22741 agtcggattc gatggagaat tgatgattac ggcttttgtt ttttctgaac gtgcttgttc
    22801 tagctgttca acagtaactt tccagctatt ggattcttcc cctttcacaa agacaggaag
    22861 tccttctgcc agttttactt gctcaccgta actgacccag taaggcacag gaatgatgac
    22921 ttcatcttgc gggtcaagga tcgtttggaa aagggtatac aaagcaaatt tcgctccgtc
    22981 tgttacgact gtttgtgaag gttcatagac aagtccatag tttttcttca gataatcaac
    23041 gattgcctgt cgaagctctg ggattcctgc tgttggtgta taatagctag ctttcccgtt
    23101 gcggattgct tcgattgctg cttcttggat gttttctggt gtcgcaaaat ccggttctcc
    23161 cacagtcaaa ctcagcacat ctctgccttt tgcttttaat gccttggcct ttgccgcagc
    23221 tgccaaagtg acagacggtt ctaatcgttt tgttcttttt gataactcca tcccattcat
    23281 tcctttacct tttaaattcc cttgattgtc ttgacttcat ctccagattc aaagccaatc
    23341 aggtaataat tcagtttccc atttgtttct tttcctacta cttcccacac aggctgatca
    23401 tcatacatcc ctaaagcagc tttttcgatt tggatttcag gatgggccgc agcaattgtc
    23461 tgttttgctt cgttttcagt cagtcccttt gtttgatcca atacttttac tttttcacca
    23521 gatttaggaa tgataacggc gatttctttt cctttatcat ttgtacctgt cagtgaaaag
    23581 tatgtcttct ttcgagtaaa ccaataaaaa tgatcggctt cctcaagatt tgcatatttc
    23641 tttgcgattt ctactgcttc tttcttcgcc tgcaccgccg gacgactgga acgcaagtaa
    23701 aaaatcgagc tgatcacgat gaccgctaat aaaaatacga tcaagccaag taacacgcga
    23761 ttaatcgttt tttcctttgt ctgttttttc ttcaagggtc gtcgctcctt tatcttcatt
    23821 ccttttcatt atagcagatt ttaattatga aaaaagacag ctcctctaac ttccttcttc
    23881 atttttcttt aagaattcat ggatgtcctg atagatttcc tccatagcta gctctttgat
    23941 cggtactttt ttcggtaatg catggatgat ccgtgcacca tattttgcag tgactagtct
    24001 tcgatccaaa ataagcaata cgccacgatc tgtctccgtc cttatcaagc gacctaatgc
    24061 ttggcgtaac ttcaaagctg ctttaggtac ggattcctgg taaaaaggat tgatcccctc
    24121 tgattctaaa taagcgttcc tagctttgac catcgggcga agcggattat cgaagggtaa
    24181 acgtgtgact acaacgatct gcaaagcatc cccaggcaaa tctacacctt cccaaaagct
    24241 gtcagcgcca aacaatacgc ttttttctga caaaatgaag cgtttcaaaa gcttctcccg
    24301 gcttccgcca aacccttgag ctagtatttc tcgtcctttt tctagcatag acagatgcat
    24361 tttctgatag accttctgca aaacatcatg agaagtgaat aacacaagta ttggccgatc
    24421 ttcttgttcg atcagacctg taagtgctgt ctctaaataa tcgatatatg cttgattgct
    24481 gacttgatgg acggcaggtg cctcttttgg cacatagatc cttgcctgtt tctcataatc
    24541 ataaggagag gcaatcactt taagaggtgc tgcttcaatg ccaagccgct tagagagata
    24601 gtgtcgatta gggccgatct tcagcgttcc tccaatataa agaatacgat catatcgagg
    24661 ataccaaaca gtcgacggca acatagccgc ttgaaaatca tggagatgaa aaatcatctg
    24721 ctgcgctgtg ttcccaggaa cgaaccaatg gatcaaatga tctcgccagt cttccagcca
    24781 ttgatccatc agcaagtact gcttgtctaa ttgatcaaat aagctatata aacttgctaa
    24841 atcgatccgc atctggtttg tccagctttc ttggataatc tcaaaagtca gacgcatttg
    24901 tgactgtagc tgctggatct cctgataaaa aagctgcagg tgatcaatgg ctgtcccaga
    24961 ttccagtggc agctgatcca acatctcttt tgtcatcatg acttcttctg gatactgtcc
    25021 gttaggttgc ttgccgctca ctaaactcat taatccttct gccatacaaa tctgtgcttc
    25081 gcatagcgca gaaagttctt ctcgataaat cgataaccag cgtaaggctt catgttcttt
    25141 cggtaaatag ctttgtattc ggtcaaacag ctgatttggt tcttctaatt gctggatttg
    25201 tttatggaaa tagttaatac ttaatcgttt gtcatttact ttttcagcga tttccggcaa
    25261 atgatgtact tcatcgatca acaaaaatgg actagctgga agcaatggtt cttttcgctg
    25321 tgtttcttgt attaaaaacg catgattgac aatcaaaaaa ttactttgcc tgattttctt
    25381 ttgcaagaaa cgaacaaagt cttgttcgta aaatgactga tttcttgcta aaaatccaat
    25441 acctctgtgc gcgatatctg caaagaatga atggttcaaa tttgttaaat gtaattcatc
    25501 caaatcaccg gtcttcgttt gcgtcagcca aactaagacc gccatttgat acaaagcata
    25561 ttgtttttgt tctggcggtt ccacaagtgt gcctttaaaa cgctgtaaat caatatagtg
    25621 gcgatagctt ttgataatta caggttgtat gggctgatct agcaattgat tcagcaatgg
    25681 aatgtctttt tctatgatct gctgctgcaa aactagcgaa acggtactga tgacagcggg
    25741 tttttcaggt gtagccaaat aactcaatgg cagcagataa ccgattgttt tacccattcc
    25801 tgtagctgct tcgatcatca aatcttttga ttcatctttt gtgaaatggt cgtagaccgc
    25861 attcatcagt ctgttctgtt cttttcgata catcagtgtt ttaccaaaca ttttttcttt
    25921 tgcttgtttt tttcttggat atgtccgctc gccataatgg acggatgtga atagttccac
    25981 ttcttttttc tgcaaagcta gcccatcgac gatttctaat gagggatcaa gtggctctgg
    26041 tttttctttc atttcttcaa tcacatgata aatgaaacga ctcgtatcca tacctgtgtg
    26101 tctacttaat cgcgcaatct gctctaacgt gatgattggc aattttctca tccgttcttc
    26161 gatcagcaaa agaagttgac ccgtcacttc ggcatcacta tctgcctgat gaggattctc
    26221 atgaataaat ccaaggcttt ctgacaaatc agctaagcga aagcttggtt ccgtcggcaa
    26281 gaaaatttgt gcaagttcta ctgtatcgat gcctggtatc ttcaaactag gaagtccgca
    26341 tcgcatgagt tcatggttca aaaaattata atcaaaataa atattatgcg cgacaaatat
    26401 ggtgtctgcc aaaagattgt aaatcgtttg ggcgacatct tcgaaataag gcgctttttg
    26461 gacgcgttga ttcgtgatcc ctgttaaatg ctggatttgt tttgaaatct tccgccctgg
    26521 atgaatatcg atcgaaaaac gtgaagtgat ccgacctgat tcaatcatga cgcagccaaa
    26581 ttggatgatc cgatcttctt ttggattcgt cccagtcgtt tcgatatcaa cgactgcata
    26641 agttcttggt ttcaaaatat cttcctcttc tcctgcctct aatgttcttt tgaaattata
    26701 ctacaaagtg cagaaaaata ctctcatcgc tttttaaaga aaatagacaa aaacgcccag
    26761 acacgcaaat gtctgggcgt ttatttttta gtataggtta attaagcttt agtaacgttt
    26821 gttgcttgag gtccgcgttg gccttcttca acatcgaaag ttactgcttg gccttcttct
    26881 aaagttttga atccgtcgcc ttggatagct gagaaatgaa cgaatacatc gtttccgttt
    26941 tctgcagtga tgaatccaaa tcctttttct gagttaaacc attttactgt acctgtttcc
    27001 ataataaaaa tcctccttgt gtatcaacac atattttgca attacttgaa tggtgtatat
    27061 ctggaagatg tttatttgaa acaagctacc acagattacc gaacaaaaac tactcctata
    27121 gtatatcata ccgtttacaa aaaagctaga gtttttcgac tttttttatt aaaaaaagtt
    27181 ttctcagcga ttacataaag tgaaaaaccg aacttttttt aaaataaacg acatattgtt
    27241 cagttggtgt ttttttgctc tgatgttctt ctttaaacta aaaaaattat tctttctgac
    27301 tacttatcgg ttctgtttca acggtcgagg ctggggaaga ttctttagta ggtctgatgt
    27361 tctcatggta tttctgatag cctatgacag ttaccagaag aacaaggcaa accaatacga
    27421 tcaacgagat tagtttttct tttttgctca tatctatacc tcataaataa caggatgatg
    27481 tccatcatat ttctgagtat gagtaaaagc aaaagctgca gctgtagaat gtaagaaatg
    27541 ccagcaactt tcataatcac aggtcggaca gtaccaaaag taaccaaatc ttggctgcaa
    27601 agaccgttct tctgtttcag gaatcgcaga atcaagatct gttgtctgta cataaacatt
    27661 tttgtacaga cgtgtgcctg taataggaga ccgctgtgtt tcttcagcaa aaactggctg
    27721 acttgttaaa cttagggata gaaacagcaa acaccataac agtctttttt tcataaagac
    27781 ctccttatcg ataagttttt cccaattaaa atcatatctc aagaacgccc gttattcaca
    27841 ttttgttcat aaatgatgtt ttttgtatca taatcgtcaa aaagaggtcg tgaccacgtc
    27901 acaacctctt tttt
//
LOCUS       DAYNVV010000034        27506 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.034, whole genome shotgun sequence.
ACCESSION   DAYNVV010000034 DAYNVV010000000
VERSION     DAYNVV010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27506
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.034"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            207..746
                     /locus_tag="ACGXWR_001646"
     CDS             207..746
                     /locus_tag="ACGXWR_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803215.1"
                     /translation="MWSLVGIVLIIFTVTAATEANYSHKIQSYKGRLVMTKKDVTRYT
                     SSRTGGLYDYAPLDALKYKDHLKKHEVKVGDRWENASHKAYNSKIVYTVEDADEQNIT
                     LPVFNYWGTVVKVNGKKSTIENDNGLVSIKGTGKRTIVEVSSTYPTTMILSLLISSIT
                     FIFLFTRYLIRCCGEMKID"
     gene            1766..2935
                     /locus_tag="ACGXWR_001647"
     CDS             1766..2935
                     /locus_tag="ACGXWR_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFK0803216.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            3408..3962
                     /locus_tag="ACGXWR_001648"
     CDS             3408..3962
                     /locus_tag="ACGXWR_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFK0803217.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(4135..4572)
                     /locus_tag="ACGXWR_001649"
     CDS             complement(4135..4572)
                     /locus_tag="ACGXWR_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFK0803218.1"
                     /translation="MFSSEENKPLYLDYVNHNLKIIIKENNLKHITLHGFRHTHCSLL
                     FESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFMSSTEEKQGSLQK
                     VKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            4620..5567
                     /locus_tag="ACGXWR_001650"
                     /pseudo
     CDS             4620..5567
                     /locus_tag="ACGXWR_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634498.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
     gene            5838..6273
                     /locus_tag="ACGXWR_001651"
                     /pseudo
     CDS             5838..6273
                     /locus_tag="ACGXWR_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345965.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit A"
     gene            6289..7122
                     /locus_tag="ACGXWR_001652"
     CDS             6289..7122
                     /locus_tag="ACGXWR_001652"
                     /inference="COORDINATES: protein motif:HMM:NF012742.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFK0803219.1"
                     /translation="MLYFSAIDNADFVFSDPFTAEVLSGIEEQAKNHGYFVLVHNVNS
                     AEDVKTIQRNWRFEGFIVVGVRVKEFLELNNVFDGPVVYIDTHLSKETLRELEQQMNR
                     LFVNTNDYQASTLAVEHLIHYGHEKIAFLSFDYIVGEPSVIQERHQAYIDTLKKYHLT
                     FKSHWIYNNSEFERIYQELAEFTAIVVTGDYLAAKLVKFLKNKNKRVMEQLSIIGFDD
                     ITFAELMDPALTTIRLNPGNKGAIAFHQLIGLAKQEEIKNQVLLLEGELISRDSVHKI
                     K"
     gene            7367..8392
                     /locus_tag="ACGXWR_001653"
     CDS             7367..8392
                     /locus_tag="ACGXWR_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFK0803220.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            8530..8655
                     /locus_tag="ACGXWR_001654"
     CDS             8530..8655
                     /locus_tag="ACGXWR_001654"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803221.1"
                     /translation="MKHFKKIALTGIAVLTGTLLAACGGGDSNSKDGQVTLSYAS"
     gene            8680..9795
                     /locus_tag="ACGXWR_001655"
                     /pseudo
     CDS             8680..9795
                     /locus_tag="ACGXWR_001655"
                     /inference="COORDINATES: protein motif:HMM:NF024808.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
     gene            9878..10774
                     /locus_tag="ACGXWR_001656"
                     /pseudo
     CDS             9878..10774
                     /locus_tag="ACGXWR_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338086.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
     gene            10790..11614
                     /locus_tag="ACGXWR_001657"
     CDS             10790..11614
                     /locus_tag="ACGXWR_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0803222.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            11646..12956
                     /locus_tag="ACGXWR_001658"
     CDS             11646..12956
                     /locus_tag="ACGXWR_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HFK0803223.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            13104..14363
                     /locus_tag="ACGXWR_001659"
     CDS             13104..14363
                     /locus_tag="ACGXWR_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFK0803224.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            14373..15245
                     /locus_tag="ACGXWR_001660"
     CDS             14373..15245
                     /locus_tag="ACGXWR_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0803225.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            15257..16087
                     /locus_tag="ACGXWR_001661"
     CDS             15257..16087
                     /locus_tag="ACGXWR_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0803226.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            16127..18310
                     /locus_tag="ACGXWR_001662"
     CDS             16127..18310
                     /locus_tag="ACGXWR_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFK0803227.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            18371..19591
                     /locus_tag="ACGXWR_001663"
     CDS             18371..19591
                     /locus_tag="ACGXWR_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFK0803228.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            19588..21048
                     /gene="gtfA"
                     /locus_tag="ACGXWR_001664"
     CDS             19588..21048
                     /gene="gtfA"
                     /locus_tag="ACGXWR_001664"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HFK0803229.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            21125..22231
                     /locus_tag="ACGXWR_001665"
                     /pseudo
     CDS             21125..22231
                     /locus_tag="ACGXWR_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            22553..22762
                     /locus_tag="ACGXWR_001666"
     CDS             22553..22762
                     /locus_tag="ACGXWR_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFK0803230.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            22755..22904
                     /locus_tag="ACGXWR_001667"
     CDS             22755..22904
                     /locus_tag="ACGXWR_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HFK0803231.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            23058..23723
                     /locus_tag="ACGXWR_001668"
     CDS             23058..23723
                     /locus_tag="ACGXWR_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFK0803232.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(24007..25092)
                     /gene="xerS"
                     /locus_tag="ACGXWR_001669"
     CDS             complement(24007..25092)
                     /gene="xerS"
                     /locus_tag="ACGXWR_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HFK0803233.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            25426..25659
                     /locus_tag="ACGXWR_001670"
     CDS             25426..25659
                     /locus_tag="ACGXWR_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HFK0803234.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            25656..26063
                     /locus_tag="ACGXWR_001671"
     CDS             25656..26063
                     /locus_tag="ACGXWR_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HFK0803235.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(26514..27023)
                     /locus_tag="ACGXWR_001672"
     CDS             complement(26514..27023)
                     /locus_tag="ACGXWR_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803236.1"
                     /translation="MKKVLFAVSLVVNIALAGGLFYTITEMNKLDDQRESLAISNEQY
                     KRKLDEASSTNVDTQEAVESSTIVYSNESSETLTNSERSTAPATETVSQKATITIGSK
                     VFTFIVNGLTIEHDSSRTGKMTELSHEFPVIVTTPSATLNGILVQDNNDNNCYIMVDG
                     QTLYRGTYQ"
     gene            27139..27506
                     /locus_tag="ACGXWR_001673"
                     /pseudo
     CDS             27139..27506
                     /locus_tag="ACGXWR_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         9474 a         4095 c         5125 g         8812 t
ORIGIN      
        1 aaatggaacg ctcttcggct tttcggtgtc tactgaaatc aaggtattaa tgggaataac
       61 agcctaagat atttggagtt cagagagggc gcgtttgatt ttcaaacttc gcaacagaac
      121 cgagaacctt gggttttcaa gtgctttttg gttcattaat cttaaccata gtgtttttaa
      181 agtggaaaac aagcaacaaa aaaagtatgt ggagccttgt aggaatagtt cttattattt
      241 ttactgtgac tgcagcaaca gaagcaaatt attcgcataa aattcagtcg tataaaggtc
      301 gtttagttat gaccaaaaaa gatgttacac gttatacatc ctcaagaact ggaggcctat
      361 atgactatgc accattagat gcattgaaat ataaagatca tttaaagaaa catgaagtaa
      421 aagttggtga tcggtgggag aatgcatctc ataaagcata taattccaaa atagtctata
      481 cagtagaaga tgccgatgag caaaatatca cattacctgt attcaattat tggggaacag
      541 ttgtgaaagt aaatgggaaa aagagcacta tagaaaatga caatggttta gtgtctatta
      601 aaggtacggg gaaaagaact atagttgagg tttcatctac gtatccaact acgatgattc
      661 tatctttatt aattagttca ataactttta tattcttatt tacacgttat ttaataagat
      721 gctgcggtga aatgaaaata gattagatag atattataaa tatgttgatt ctattttcat
      781 agcaatggag aaaatacatt agcaatatat aaaagaaggt atcaagagtc acagtgaatt
      841 tattccgaaa agtgaaaaga gcaaatataa aatttaatga aaatatagaa ctaaatagga
      901 aaacgtagac gtaattttct acgttttcct tttcatatat attaaatatt acggaaaatt
      961 atataaacta atttagtgtt ttgtttgtaa ttcctaattt tgctccactt ttagataatt
     1021 tttaggtcta tttaactcat cagacattct atgctcattt ttctccaaat ttgtttcaac
     1081 tctttcgtac ttaattttgc gtatttgaaa attcttcttt tagagtactt ttattacgat
     1141 actagtatga tatatatcta tagcaaacag ttaaaatctt cctaaaataa gcgaatagca
     1201 ttcctaaaac ctataaaatt tttagatgaa gcgacaagtg gacaattaat aaactacttg
     1261 aacatgaaat tatggatcac ctttcaaatt tagaaaatgg aattcttata cttattgcgc
     1321 aacatttatt gattgcaaaa ttatgtgaca aaaaaaacta gtagaagaaa gaataatggc
     1381 ttgataataa agtactacct attaaaggta gtactttatt taatttagta taaattaaca
     1441 tactactata ttttaggttt catattatat aaattaataa tatactacca tttgttggta
     1501 gtataattta aaggtaataa gttattcttt tattactatg tttgggtttt atagcaaaga
     1561 aagtttaata agagtttgga cctagcaaac aatattaatg aggtcattaa atcttattat
     1621 ctttagtgat ataacgaaat atctacacag acaaaatgat agcgtaaaat attttgtgta
     1681 aatagatatt tagggtagaa aaaaagaaag tccattctgt aaaattaaag ttaccacaac
     1741 cgaaatttta taggaggact ttctcatgcc caattttact acagaaatta tggaaacact
     1801 aatcaataaa ggtgatttag atgaattatt tcgatgtcat ttagaattag ctgttaattc
     1861 attattgcag gctgaattaa cagcttttct tgattatgaa aaatatgatc gtgctgggtt
     1921 caattcaggt aattcccgta atgggaatta ttcacgttca ttcagaacag agtatggaga
     1981 attaaatttg gtaattccta gagatagaaa tggtaagttt tctcaacaaa ctttacctgc
     2041 ttataaaaga accaatgact ctttagaaac cactattatt cagctatttc aaaaaggaat
     2101 tactatgtct gaaatctctg aattgattga aaaaatgtac gggcatcact atacgccaca
     2161 aaccatttca aatatgacta aaatagtttc tgaagatatt attgccttta aagaaaggtc
     2221 cttagaatcc agatactctg tcatttttat ggatgctact cacattcctt taaaaagaca
     2281 aactgtttca aaagaagcag tttatattgt aattggcatt cgattagatg gaaccaaaga
     2341 ggttcttggg tttagtcttg ctccaactga atctgcttat gtttggaaag agattcttca
     2401 agacctaaaa gaccgtggtt taaaagaggt tttattagtc gtaactgatg gtttaagtgg
     2461 cattaacgat agtattcata gtgtttatcc aaatgctcaa tttcaacaat gttgtgtcca
     2521 tatatctaga aatatcgctc ataaggttcg tgttagtgat cgacaagaaa tctgtagcga
     2581 tttcaaatta gtttatcaag caagttcaaa agaagaagca aataatcaaa taaggtttat
     2641 gatagataaa tggaaaaagc agtatccacg agtggttaaa ttgctcatga atcctgctat
     2701 attaaccttt tataatttcc ctccgtcaat cagaagaact atttattcaa ctaatttgat
     2761 tgaaggtttt aacaaacaat taaagaaata taccaaaaga aaagagcaat ttcctaatga
     2821 agaatctctg gagagatttc tagtatctca attcaacaac tataatcaaa agtttctatg
     2881 ccgagttcat aaaggtttta aagaaataca tgatacatta gaatcaatgt tttaacttga
     2941 tcaacagaat gggcttttcc atttacacaa aattattgac gctcccgaca aaattatgat
     3001 cttgcgtaaa gttataaaat attaataaaa atattttatt aatgaaaagc ttggtagcac
     3061 ggttattcat atgctaattt atttcacttt atagtaaggg gagttcttag tatattgttc
     3121 aaacttaaat ttcatataat ttaattatgt aaattagcta ttctaagaac ttctacggat
     3181 aactgcccgt ctaaaattta aataagagct tagaatcttc atataagtaa ggttaatttt
     3241 tttgtacaaa aaagtcggaa tattctgagt tactgaaatg atataaaatc ataaactaaa
     3301 tcccttgatt ttattgactt tcaaaagttt atatatataa gttaatgatt atggtaaaat
     3361 atatacataa tcattaactc agaatatttt taagaaggga aacaatagtg agctataatg
     3421 tacaaccgtt aaggacaaat gaagagatac aagattttca gttttggcta agaagaacaa
     3481 gtaatccgga aagagatagt tttttatttt tgtttggaat caataatggg ttacgtatgt
     3541 cagatattat aggattaaaa gttggagata tacgaggcaa aagtaagcct attattgttg
     3601 aacataaaac aggtaagcga aaaccgattt ttatagataa tttgagagaa gaaattttat
     3661 tatatactga aggtaaagaa gaaaatgatt ggttatttcc gagtcggcaa caaggtcgac
     3721 atataacaag ggatcgtgtc tatcagatat atgcagatat agcagaaaaa ttaggacgag
     3781 atgatatagg aacacataca ttaagaaaaa cttttgggta tcactactac aagaaaacta
     3841 gagacattgc taccttaatg tttattttta atcatagctc gcaagcaatt acaaaaaggt
     3901 acattggtat aactgaagat gaaataggag catcacttcg tggatttaaa ctaggtgtat
     3961 aatttaaaaa tttttataaa cagtaaagac aaagattaaa agctattttt atctagaacg
     4021 attttatttc ataaagttcg cggaataaaa gctggggtta ctggtacttg gtataggttc
     4081 gtgttatata aactaagtaa ttaaataaca tttttaggtt ggaaaaggat gaaattaaaa
     4141 aaagagaatc aatacggtct caaaaacgca aacgctgcgg aataagaaaa atactgataa
     4201 ctcaacgttt agcagactat ctaataggga tagtctgctt ttttcgtttt tgaccatact
     4261 tttgaccttc tgcaaacttc cttgcttttc ctctgtagaa ctcatgaaat ctgcaaaacg
     4321 aattgccgtt tcctctgtct gctttttcgc gatatgggtg tatatatcat ccatagtggt
     4381 tttaatatct gtatgtccaa gtcgaacata cacttctttg acagacgcac cagattcaaa
     4441 gagcagacta caatgggtat gacgaaaacc atgaagtgtg atatgtttta agttattctc
     4501 tttaatgatg attttcaaat tgtgatttac atagtctaaa taaaggggct tattttcttc
     4561 tgatgaaaac aaaagttgtt caccatcttt tataggtttg attctcattt ttagatatta
     4621 tgcccgcacg tattcatcac atttctattg tgaatcgctt tattcgaccg acatttgact
     4681 tttatcataa tatactcggt ttaaaattac taatgaaaac aattaatcaa gacgatcata
     4741 ccatgtatca cctgtttttt tcagataatc accaccgtgt gggaactgaa ctgacttttt
     4801 ttgaagtaca agaagggaac aaccagtttt ttggaaccaa tacgattgaa cgaacgatac
     4861 taaaagttcc ttccgaagca tcattgcatt tttgggaaat atattttgaa acacaaggcg
     4921 tttgccatta tggaatcgaa tcattttctg gacgacctat cttacgtttt gaagggccag
     4981 atgcaacacg attagcttta gttcccttac gcgaatttga agatattgat gattatttcc
     5041 cgtatgtcac agaccagatc cctacagagc atgccatttt aggaattgat gccattcaac
     5101 tacgcgtaca atattccgat gcgactgaac gagagttatt gtcggtaggc tggtagcaca
     5161 aagaatacgt cagtttcttt tcgggtcatc aacgagtgac aatcttagaa aatcaagaca
     5221 ctcagttcta tcaagaagtt cagattattc aagatcgtga gaatccagtt gccattgaag
     5281 ggattggtag cgtccatcat gttgcgtttg gcgtagaaaa taaatctgat ttacaacgca
     5341 tcgacaaaca attacaagag cgcaatttta taaattcagg aataaaagat cgtgaatttt
     5401 ttgtatcact ttattatcgt gacccaaatc aattattgat tgaaattgct acaggggaag
     5461 gaaacctaga tgcaaaagcg tatgaaaatc aaagtccacg ctttgaagaa attcctttat
     5521 ttttaccgca gtacttaaat ttcattcgtg aacaagtgga gcaataatta gctaatcaaa
     5581 tccatgacga agagtaagag gttgactcat aagtcaaaaa ataaagaaaa acgcatcaaa
     5641 tccattctaa agaatgttga tttgatgcgg ttcctatttt tataaactat cattttcgac
     5701 taataaaact acttatgagt cagcctctct ttttttcttg atttttatac ctctttctag
     5761 gtaaactaaa catctgccaa aaataccgtg tctcattgaa acattctcaa ctatttcaaa
     5821 ataaagggga gtaccaaatg aacgagtata ttgaaattat ccacgcaaga gaaacaactt
     5881 aaaaatgtca gtctcaaaat tcccaaaaat aaaattagta tttttaccag cgtatctggt
     5941 tcaggaaaat catcgattgt ttttgatact attacccaag aagctggtcg tcaactgaat
     6001 gacacctatg atagttttac ccgtttattt ttacctaaat acagtcgtcc agaggttgat
     6061 gagattgata atctttctac ggcgattgtg gtcaatcaaa agaagattgg tggcagtgcg
     6121 cgctcaacgt tagggacgat tactaacatc aatgcgttat ttcgtgtgtt gttttcatgt
     6181 tttgcaacac ctagtttagg atatgcaaat gcttattcat ttaatgatcc tagtggaatg
     6241 tgttctgtct gtcagggaat cggtaagacg attgcatttt taataggatt gctttatttt
     6301 tcggctattg ataatgctga ttttgtattt tctgatccat ttaccgcaga agttttgtct
     6361 ggaattgagg aacaggcaaa gaatcatggt tattttgtat tggtgcataa tgttaattca
     6421 gcagaagatg ttaaaactat tcagagaaat tggcgttttg aggggttcat tgttgttggt
     6481 gtacgtgtaa aagaattttt ggaattaaat aacgtttttg atggtcctgt tgtttatatt
     6541 gatacgcatc tttcaaaaga gacattaaga gaacttgaac aacaaatgaa tcgtttattt
     6601 gtaaatacaa atgattacca agctagtaca ttggcagtgg aacatttgat tcattatggt
     6661 catgagaaaa tagcgtttct ttcttttgac tacattgtag gtgaaccaag tgttattcaa
     6721 gaacgacatc aagcttatat cgatacatta aagaaatatc atttaacctt taaatcgcat
     6781 tggatatata acaactctga atttgagcga atttatcaag aattagctga atttactgca
     6841 attgttgtta ctggagatta tttagcggct aaattagtaa aatttttaaa aaataagaat
     6901 aaacgagtga tggaacaatt atcgattatt ggatttgatg atattacttt tgcagaatta
     6961 atggatcctg cgttgacaac aatacgacta aatccaggta acaagggggc gattgctttt
     7021 caccaactga ttggactggc caaacaagaa gaaataaaaa atcaagtact actattagag
     7081 ggagaattga tttctcgaga ctctgttcac aaaatcaaat aaaaaagctc tgtgaaataa
     7141 gtatagttaa caataaaata tccgaacgat agagagaatg aactgtgatc tagcagttcc
     7201 tcgtcgcaaa ttcactagaa ttagcattat ttactctaaa ttgttcggat attttttctt
     7261 gtttttaatt atgattacag tgcctatttt taacgaaatt tgcttatttt caaaatgtat
     7321 gattatatgt tagtaaacac tttcaaatat gaaaagagga gctattatgg taggaattag
     7381 ggatgttgca aaacgggcgg gtgtgtccat tgcaacagta tcgcgcgtgc taaatgagga
     7441 tccgacactt tcagtaaccg atgaaaccaa acgaaagatt gcagaatcgg ttaattttta
     7501 tcattatgtc aaaaaaagtc ccgttgcaaa aaatttaaca aatattgcat taataacgac
     7561 agtttctgaa gtagatgagt tggaagatcc ctattttcga acgattcgca gagggattca
     7621 agtcgaagca gaacaaagca aagtcaattt gaagaaaatt attcgtttgt cagaaacacc
     7681 gttggagcaa gacgatttgc taaaatgtca aggtgtgttg attattgggc aggtgctatc
     7741 ttctgtgatt gaagaagtat cagcaattaa ttcgaatgtc gtagtgattg atgaccctag
     7801 tattgaagct gaagtagatg cagtttatac tgatttaaca aaagcaacga atcagcattt
     7861 agatcgattg tataaaaaag gacaccgaaa cattgcgttt atcggaggag gacgtgttcg
     7921 tttagatagc caaggaaata aacacgtgtc agatgatgat tatcgaaaaa tagcctatga
     7981 gacgtggatg aaacaaaaag gattagaaaa atatagtcaa atttatttag aaggctggac
     8041 cacacttgac ggaatgcagg cagcagattt acttttgaaa aaacatgcta aagataagtt
     8101 gccgactgct atcatggtag gaaatgatcc tattgctgtg ggggtttatc gttcacttca
     8161 aaaaaatggt ctacatattc cagaagatat ttcgattgtg agttttgata atattgaagt
     8221 tgctgaattt ttaacacctg cattaaatac ggtgaatgtg aatacagaag aaattggaaa
     8281 actagcagtt cgcatggtta atgaacgaat aaaagaagtt agaaatgttt cgatcaaagt
     8341 gattgtttct aataatatta ttgttagaga aagtgaaaaa aatatcgatt aaaaaagtaa
     8401 acatccaaaa aagggtgttt acttttttgt ttactaatat ttttagtaaa aaatctcgac
     8461 aaaacattaa gtaaacagtt atggtgttgt taacaaaaag aaaacgcatt caaaacagga
     8521 ggaattaaga tgaaacattt caaaaaaata gctttaacag ggatagctgt tttaactggg
     8581 acattactcg cagcatgtgg tgggggagat agtaattcta aagacgggca agtaacttta
     8641 agctatgcga gttgagatac tgaccaagct ccaggactaa gaaaaatgtt agatgaattt
     8701 gaaaaacaaa atcctgatat caaagtagaa atggagacaa cgccttggga tcaatattgg
     8761 gttaaattag aagctgcaac aacgggaggt aatatgccag atgtagtaac catgcactct
     8821 agcgaatcct ataaatatat gtcacagaat gctttgatgg gacttgatga tgttatcaaa
     8881 gaaaatgata ttgacatggg aaactttact gaaggaattg ctgatttcta tacgcttgaa
     8941 gacgaactat acgcaatccc taaagatgct tctgtagtgg ggctatggta caacaaagaa
     9001 ttatttgata atgcaggtgt cgattatcca gatgaaacat ggacatggga aacactcaga
     9061 caagctgcaa ttgatttaac agatgaatca aaaggcatct atggttttgc atcacatatt
     9121 ggaacagaga ctggctactg gccatttatt tatcaaaatg ggggagaagt atttgccgat
     9181 gacaatacaa aatcaggttt gaatacccca gaagcacaag aagctttagc tttttatcga
     9241 gatattgcac ttgttgatca tgcttcacca acaattacag aattacaaga tcctgataag
     9301 ttaagtcgtt ttcaatcagg tagattagca atgatgattg aaggaaactg gtttgcaccg
     9361 ggatttttga aaaatgacta tctagttgaa aatgttgctt ctgccgtgtt acctaaggga
     9421 aaagttaatg caacaattac aaatggactt ggttgggctg ccagtgcgag tacaaaatac
     9481 ccagaagaag tgaaaaaact aatggcattt ttagctagtg aggacgccaa taaaatccaa
     9541 gcggaaacgg gggcatcaat cccagcacta aaaggctttg aagacgagtg ggctgcttct
     9601 tcagatacaa ttgatttgag tgcttttgga aaaatgttgg agtatggagt ccctcgtcca
     9661 tacaataaag atggattacg agctgaacaa gcagaagttc aaattattaa ccgtattctg
     9721 tctggtgaag taactgttga agatggaacc gctcaaattg aaaaagaagt caatgcgata
     9781 ttgagcggaa attaaattag ttaattatac aatatacagg cgaaaggatt ctatttcgtc
     9841 tgtatattaa tggatgaata ccaaaaaggg ggatattatg aaaaatcgaa tttttggaaa
     9901 atatcgtaaa gatcaagtga tatggggcta tatttttatt tttccaacgg cattaggatt
     9961 aattttatta aatatatggc cagcaattca aacagcaatt ttaagttttc aaaaaacggt
    10021 agggttcggt gatactgaat gggtcggatt aagaaattac caaaaaatgt ttgcagacgg
    10081 tgaagttttt cagtctttat taaacacatt aatttatgca gtggtttcga tacctagtat
    10141 tgttgtatta tccttgttgg tggcagtttt aatgaataga aaagttaaag gattgtcgat
    10201 ttatcggaca atttattttc taccagtcgt tgctgcacca tccgcagtcg caatgatttg
    10261 gcgctggatg ttcaataatg attatggact gattaataac atgttggcta aaataggtct
    10321 cgatggacca gcatggttaa cggatccatc gattgcgatt tattctatta tcattgtagg
    10381 agtttggagt gctattggtt ataacatggt gttattacta gccggcttat aagaaattcc
    10441 taaaaattat tatgaagcag cggaaattga tggtgctagt ccaatccagc agtttttcaa
    10501 cattacgtta ccattagtta caccaacatt attttttgta gttgtaacaa cagttatcaa
    10561 tgctttccaa gtatttgatg ttatttttat gatgattact cctaatagta ccgccatgtt
    10621 taaatcacaa tcattagcct atttattcta taaacattca tttattttaa atgacaaggg
    10681 atatggttcg gcaatcgtta tgttcctttt agtgattata ttaattatta ctgcaattca
    10741 aatgaagttg cagaaaaagt gggtaaacta ttaaggaggc tatcaaatta tgaaaaataa
    10801 atttttttca aatgcgccaa tccatatcat gcttatttta ggtggtattg caatggcatt
    10861 accttttatt tggatgattt taacttcagg gaaaacgttg gttgaatcta cccaaattcc
    10921 acctacaatt ttccctgaga aatttcagct aagtaactat caacaagtac ttgatttatt
    10981 accattcatg gctttttata tcaatacatt tttaatggtt gttggacgag tgattggctc
    11041 ggttttattt tcagcaatgg ctgcatatgc ttgtgcgcgt ctaagttttc cagggaaaaa
    11101 tatccttttc agcttagtac ttattcaaat gatgattccc ggttccattt ttattactcc
    11161 acagtattta ttagcacaaa aattgggtat tttaaataca attccagcat taatattacc
    11221 aggggtagtt agtgcgtttg gtacgttttt attaagacaa tttttcttag gtttacctga
    11281 tgaattggag gaagcggcct atttagaagg tgccaatatt tggacgatct ttttcaaaat
    11341 tatgttgccg cttgctaaat caggattggt tgcacttgga atattcacag cgttgtttgc
    11401 atttaaagat ttaatgtggc cattgattgt caatacttca attgataaga tgcctttagc
    11461 tccgggatta gcaaacttac aaggacaata tgccacgaac ttcccacaat taatggcagg
    11521 ttcgttatta gcaatttggc caatagttgt gatattcatc gttttccaaa gaaaattcat
    11581 tgaaggaatt gctacaacag gtagtaaatt ataaaactat taattagtga ttggagagta
    11641 agtacatgac aaaaattaca tttattggtg caggaagtac tatttttgca aaaaacgtat
    11701 taggcgatgc gatgttaact ccaagtctac aagatgcaca tattgcattg tacgatattg
    11761 atgaaaaacg actaaaagaa tcaaatttaa tgcttaaaaa tattaataaa aattcgaatg
    11821 aaaatcgtgc tgatattgtt tcttattatg atcgcaaaga agcgttaaga gaggctgatt
    11881 ttgttatcaa tgctattcaa gtgggtggtt ataaaccttc aacagtgatt gattttgata
    11941 ttcctaaaaa atatgggttg cgacaaacta ttggtgacac catggggatt ggtgggattt
    12001 ttagaaccct acggacacta ccagtaatgt tagactttgc taaagaaatg gaagaagttt
    12061 gtccaaatgc ttggttattg aactatacaa atccgatggc gatgttaacc atgggtgttt
    12121 taaaagcgac gagtattaag actgttggtt tatgtcatag cgttcaagta tgcgtaccag
    12181 aattgtttga gcatttagga atagccgatc aatatgactt aaatgacttt caatggaaaa
    12241 ttgcaggcat taatcatatg gcattcttgt tggaaattac aaaaaatggg gaagatttct
    12301 atccaacaat tcgtcagtta gctgcagaaa aaccaaatcc acatccagat tctgtacgtt
    12361 ttgaattgtt gaaacgtttt ggttactata ttacagaatc aagtgaacac aatgcagaat
    12421 accatccata ctttattaaa tcaaaatacc cagaattgat tgacgaatta gggattccgt
    12481 tggatgaata cttacgtcgt tgtgaacaac aaattaatga ttgggaaagc atgcgagagg
    12541 acattgtaaa taatggggag ttaacacata cgagaagccg tgaatatgct tcatatatca
    12601 tggattctat tacgacagga actccgtcag tgattgcagg aaatgtctta aataaaggct
    12661 taatcacaaa cttaccgaca gatgtttgtg tggaagtacc ttgtttagtc gataaaaatg
    12721 gcgtgcaacc aacctatgtc ggtgaattgc caacacaatt agctgcttta aatcggacga
    12781 atatcaatgt tcaagaactg acagtagaag ccgctttaac actagataaa tcaaaaattt
    12841 atcaagcagc gtatttagat ccacatctat catctgaatt gtctttaaca gatatcaaaa
    12901 atttagtgga tgatttaatc gaagcacatg gggactattt acctgaatat aattaaaaag
    12961 aagctgaaag agtaaggaat tttcaattcc ttactctttt cttagttaaa tttagtaaaa
    13021 atattgacaa aacacttagt aaacagttac attagtgtta acaaaaagaa aacgcattca
    13081 aattgtataa ggaggagcat aaaatgaagt ggtctaaaaa aattatttta gcttgtatag
    13141 cactaggagc aacgatctct ttgactgctt gtggaaaaaa tcaggaagat gcaagcggta
    13201 aggtagaaat agagtttttt aatcaaaaaa aagaaatgac tcaaacgatt caggagattg
    13261 ctaaagattt tgaagcaaaa aaccctgata ttcatgtaaa agttgtggat gtaccgaatg
    13321 ctggtgaagt aattaaaaca cgtatgcttg caggcgatgt accagatgtc attaatcttt
    13381 atcctcaaag tatagaattg aaagaatggg cgaaagctgg ttatttagag gacttaaccg
    13441 aagaaccgta tttagagaat atcaaaaatg gatatgcaca acgttttgct attgaggatc
    13501 gtgtatatag cataccatta accgctaatg tctatggttt ttactataac aaaactgctt
    13561 ttgaggaaat ggggattcaa gcaccagaaa cttgggcaga atttgaaaaa atagtagctg
    13621 agattaaaga tcaaaacaaa gtaccgtttg cgattgcagg agcagaaggc tggactttaa
    13681 atggttatca ccaactagct atagcgactg ctgctggtgg tgaagaggaa gcgaacaatg
    13741 tttggcgttt ctcagaagtt aatggaatta atgctgaaag caaagaaatg caaaaagatt
    13801 ttaatcgatt agatttgtta agagaaccaa aagctttgca aaacaactgg caaggtgccg
    13861 gttataacga tacagtagtt acttttacaa aaggtgatgc gttgattatg ccgaatggtt
    13921 catgggcaat gccgatgatt cattcacaaa atccagattt tgaagtagga acttttcctt
    13981 ttccagcaga tgaagcaggt caaagtctaa cgattggcgc aggagaccta gccttatcag
    14041 tttctgcaac ttctcaacat aaagaagaag ccaaacgttt tgtagaatat atgacaacac
    14101 ctgaagcgat gcagaaatat tatgatgtag atggtgcacc gtgtgctgtt gagggcgtta
    14161 tcgagaatac tcaggattca ccattaagtg gtttaactga acttgctttt actgatcgtc
    14221 atttagtttg gttagccaaa gattggaata gtgaaaatga tttttatacc ttaacaacaa
    14281 attatttaca caatggcaat caaaaagcca tgattaacgc attaaatgct ttctttaatc
    14341 caatgaaagc tgacggaagg taggaaaata aaatgaaaat aaaagaaatt ttaaatcgtt
    14401 actgggcaat catttttgta gcaattccaa ttattttgca gatgattttt ttctactttc
    14461 caatggttca aggtgctttt tacagtttaa ctaattggac tggtctgact tataattttg
    14521 attttgtggg tttgaacaat tataagattc ttttttctga tccgaagttt atcaaatcga
    14581 ttggcttcac tttaattgtg acgctttgca tgattgctgg acaaattggt tttggtattt
    14641 tgattgcgcg ggcgttgaac gcaaatatta aagggaaaac attctttaga gcatggttct
    14701 tttttccagc ggtcttatcg ggcgtggttg tttctttagt atttaaacaa atttttaact
    14761 atggtttacc aaaaattggt agtatgttag gcattgaatt tttacaaacc agtcttttag
    14821 gaacaacatg gggagcgatt tttgcagtaa tttttgtttt actttggcaa ggaattgcca
    14881 tgccagtcat cattttctta gcgggttttc aaagtattcc acaagaaatt attgaagctg
    14941 ctagaatgga tggggcgaat gataagcaaa ttttttggaa tattgaaatc acctacttat
    15001 taccaagtat ttcaatggta tttattatgg cattaaaagg tggcttaaca gcatttgatc
    15061 aaatttttgc tttaactggt ggtggaccaa gcgatgccac aacatctttg gggttacttg
    15121 tttataatta tgcttttaaa aacaatcagt ttggttatgc gaatgctatt gctttagtct
    15181 tatttatctt aattgggatt gtttcactgg cacaattaaa attatcgaaa aaatttgaaa
    15241 tctaggaggt ttcccaatga aaacatcaaa agaaaaaaat atttctaaat acttgctttt
    15301 attattaggg ggcttcatga ttttagttcc cttagtttca acgctattcg gttcatttaa
    15361 aacaacaccc gatattatga ataatttctt tcgttttcct aatccagcga ctttggaaaa
    15421 tttccgaaga ttgttagcgg atggaattgg tcattacttt tggaattcgg caatcatcac
    15481 aatcattgca gtagttgctg tgacagcaat tattcctatg gctgcttatt cactagcaag
    15541 aaaaatgact cgtgggaaag catacggatt gatgtattta tttttaattt taggaatttt
    15601 tgttcctttc caagtaatta tgattccgat taccgttatg atgagtaaaa ttggtttagc
    15661 aaatatgtgg ggattaatct tactctatct cacttatgcc gtaccacaga cactattttt
    15721 atatgttggt tttattaaac taaatgtgcc tatcagtctg gatgaggctg ctgaaattga
    15781 tggggctagt cactttacaa cttatttcaa aattgttttc ccaatgttaa aaccaatgca
    15841 tgcgacgact attattctta atgctctatg gttttggaat gatttcatgc taccattatt
    15901 aattttaaat cgtgattcta atatgtggac actaccattg tttcaatata attatacggg
    15961 acaatatttt aacgactatg gtccaagttt tgcttcctat acagtaggaa ttgtcacgat
    16021 tacactagtt tatcttgctt tccaaagaag tattatagct ggaatgagca atggagcagt
    16081 gaaataacca ataaattatt ctcattataa aggagttcat aaacttatga ttatatttga
    16141 caatcacaca caaacatttc atttacaaaa taaaaaaatt agctatctat taggaatcga
    16201 agaaaataat tatttaacgc atctttattt tggaaaaaag attacgcact attctggtgg
    16261 gtatcgctac ccccgaacag atcgttcctt ctcacccaac aatgcaaatg cgcaagatcg
    16321 tttattatct ttagacacat taccattaga atttccagga tatggacatg gtgattttag
    16381 agaaccggcg cataatatta aattaggaaa cggtagtcgt gtaaatgatt ttcgttatga
    16441 tagctacgaa attcaaaaag gaaagcccag cttagcggga ttgccagcct tatatacgga
    16501 agatgatgat gaagctgaaa cgctgattat tcaattgaaa gacgcgatta gtggattgac
    16561 tttacagttg ttctacacaa tttatcaaaa tcacagtgta attattcgtt ctacgcaatt
    16621 agtaaataat agtgatgaaa cagtggagat taaccgctta gctagtcaat caattgattt
    16681 tccaaatcgt ccactcgagt taattcattt aaatggtacc tgggcaagag aacgtcaaat
    16741 gactagagaa aaaattcata cagggataaa agtattagat agtaaacgcg gatcaagcag
    16801 ccatcaacaa aatccgtttg ttgctttagt agatgccaaa acagatgaat ttcaaggaga
    16861 ggcatatgga tttaatttag tttatagcgg taatcacgaa acggtgattc aaaaagatcc
    16921 atttgaccaa acacgggtca ttatgggaat taattcattt aattttggtt ggcaactaaa
    16981 aactggcgac tcatttcaaa cgccagaagt cgtgatggtt tatagtaatg aaggtctgaa
    17041 tacgttatca cagacgtatc atgaattgta taatcaccgt ttaattcgtg gaaactatcg
    17101 tttaaaagaa cgtcccacgt taatcaacaa ctgggaagca acgtattttg attttaacga
    17161 agaaaaaatc atgaatattg tcgatgatgc gaagaacttg ggcattgaaa tgtttgtttt
    17221 agatgatggt tggtttggcg gtcgtgaaaa tgacttcact tcattaggtg attgggttga
    17281 aacagaaggc aaacttgctt gtggtttgga aaatttagcc aagcaagtgc atgataacgg
    17341 gatgaaattt gggatttggt ttgaaccgga aatgatttct gaagatagtg aactatttcg
    17401 agcacatcca gattgggcat tgggtattcc aggtcgtgac cgctcaatta gtcgaaatca
    17461 atatgttctt gatttttcaa gacaagatgt tcgtgataat atctatcaac aaatgacggc
    17521 gatttttgat cgtgtaccga ttgattatgt gaagtgggat atgaatcgaa atatgacaga
    17581 agtctattct gtcttgttgg actcaacgat gcaaggtgaa gtggctcatc gttatatgtt
    17641 agggttatat gaatttttag aaaagttaac aacgaattat ccaactattt tatttgaaag
    17701 ttgttcgggt ggaggcggtc gttttgatgc aggtttcttg tattacatgc cacaaacttg
    17761 gacgagcgac aataccgatg ccgtggctcg tctgaaaatt caatatggaa ccagcttagt
    17821 gtatccaatt tcaagtatgg gtgcgcatgt ttcagcagtc ccaaatcatc aaacaggaag
    17881 agaaacgagt ttaactattc gtggcaatgc tgcgatggct ggtgtttttg gttatgagct
    17941 agatctaacg caattaactt ctgaagaaaa agcagaaatt aaagaacaag ttgcctttta
    18001 taaaaagcat cgccaacttt tgcaatatgg aactttttat cgcttggaaa gtccgtttga
    18061 aggcaatgat actgcatgga tgtttgtctc aaaagaccaa acagaagcca tggtctttta
    18121 tttccgagta ttagcagaag ctgcgcatcc attagtcaca ttgaaattag caggattagc
    18181 agaagaagca acttatcaaa tggaagatgt aacatttgct ggcgatgaat tgatgaatct
    18241 cggtttttat attgactcag aactacatgg tgattatgcg acacaacgct tttatttgaa
    18301 acagatatag tagcttgaat ttacaatata agtgcaacac caaaagagac tcattccaaa
    18361 cgaagaaaat atgttttatt tacacgcatt tactaaaaag cagcctgatt tgaattggga
    18421 aaatgaagaa gtacgtgaag aaatctatgc aatgattaac tattggttag ataaaggact
    18481 aggcggattt agaatcgatg cgatattaaa catcaaaaaa aaactagagt atggcatctt
    18541 tgaatctgat ggagaagatg ggttagcctt cattgggccc tggattctta atcagtcggg
    18601 cattgaagtg tggttaaaag aaatgagaga gcggacattt aaaccacata atagtatgac
    18661 ggtagcagaa gccgatgttc ctaatgaacg tttagatgaa tatattggtg aagatggcta
    18721 ttattcgatg gtttttgatt ttagttatac ggatattgat gtacctgaaa ctggtgaatg
    18781 gtttaaagat agccaatgga catggacgga tatgcgtacc aatattttta cgaatcaatt
    18841 agttacgcaa gataaaggtt ggggcgcctt atatttagaa aaccacgatc aaccacgttc
    18901 aattaataaa tatattccag aagaatggat caatgattat agtaaaaaaa tgttggcgac
    18961 gctttttatg ttactaagag gtaccccttt tatttatcaa ggacaagaac taggaatgac
    19021 caacatagaa atggcatcat tagaagattt tgatgatgta gctacgcatt ctcagtataa
    19081 acgggcatta gaatatggat tggcaccaga gcaagcattg aaagctgtca ataaacgaag
    19141 tcgggataat tctcgcacac ctatgcaatg gaatacgcaa aaaaatgcca gattctcaac
    19201 ttctgataat gtatggttaa aagtaaatcc taattatcca gaactcaatg cagaagctca
    19261 gttaaccaat caacagtcgg tattcaatta ttatcatcaa ttaattaaat taagaaaaaa
    19321 tagtgtatac aaagacgtgc taatctacgg acaatttcta ccagtgaaag ataaaaatga
    19381 acatattttg ctttatgaac gccaattaga agataaaatc gtattagtta tcttaaacgt
    19441 tacagcaaca gaacaagaat attatgtaga tgaacagtac caacaagtat taatcaataa
    19501 ttatgaagat gttttattag atcaaagtcg aaaattgcgt ttacgaccgt ttgaaagtat
    19561 tgtattagct aattatggag gacaattatg aaaattaaaa acgaagcaat gctcatcacc
    19621 tatgcagata gtttaggaaa aaacatgggc gaattaaaac aagtcttaga caaacattta
    19681 caaggtgtta ttggtggtgt acatctgttg cctttttttc catcgacagg tgatcgaggc
    19741 tttgcgccga gtgattatac gacagttgat ccagctcttg gaacatggga agatgtggaa
    19801 gcattaggtg aagattatta tttgatgttt gattttatga ttaatcacat ttctcgtgaa
    19861 tcaaaatttt tccaagattt caaaaaaaac catgagcagt caccatacaa agaaatgttt
    19921 atccgtattc atgaattttt cccagaaaat cgaccaacac aagaagatat tgatttaatc
    19981 tacaagcgta aagacaaagc gccgtttcaa acggtagaat ttgcggatgg tacgacagaa
    20041 gaggtttgga atacctttgg ggaagaacaa attgatttag atgtgaccaa agaagttgtg
    20101 aaagaattta ttcgagaaac catcaaagat atggcgaacc atggctgttc tttaattcga
    20161 ttagatgcgt ttgcttatgc gattaaaaaa ttagatacca atgatttctt cgtggaacca
    20221 gatatttggg aacttttaga cgaagtgcgt caagaagcag cgaaatatga cgtcgaatta
    20281 ttaccagaaa tccatgagca ttattccatt caaatgaaaa ttgccaatca tgattattat
    20341 atctatgact tcgccttgcc aatggtcact ctgtattcac tttatagtgg aaaatcagaa
    20401 cgtttagcca attggttgaa aatgagtccg atgaagcagt ttacaacatt ggatacgcat
    20461 gatggaattg gtgttgtgga cgctcgtgat ttattaacag atgaagaatt ggattacacc
    20521 tctgaggaat tgtataaagt cggggcgaat gtgaagaagg tctattcaag tgccaattac
    20581 aataatttag atatttatca aattaacagc acctattata gtgcattagg cgataatgac
    20641 cgtagctatc tgttagcacg tgcgattcaa gtatttgcgc cagggattcc acaaatttat
    20701 tacgttgggt tattagcagg aaaaaatgat attgaactgt tggaagcaac gaaagaaggg
    20761 cgtaatatta atcgtcatta ctatgattta gccgaaattg aagaagaagt gcaacggcca
    20821 gtgattcaac aattatttgc acttttaaaa tttagaaatg aatctgcggc gtttgatttg
    20881 gatggaacga ttgaagtagc aacgccatca gaatcagaaa tagtgattac acgtaaaaat
    20941 aaaaacggta gtgatagtgc aacattaacg gctaacttgg atacgaaaga atttatcatt
    21001 gagtctaaag atataaaaat tttcactagt gttgcattaa aattttaacc tattccatag
    21061 aacaaaaaat cctttatact agcacttgga tgacttatcc aagaccaata aaaaggactc
    21121 atacatggat aagtataaaa caaatacagc atttaataaa tggttttctg ccataaaatt
    21181 aggaaaactt tctgtcaact cccaaaaatg tatttttgat tacaattcgt atcgtaaaaa
    21241 actgtctttt gaagctgtgc tcaagctctt tctctacgca gttaatgaag aaaaagaaag
    21301 tttgcgtgat ttgagtacag ctcttatcga ccgatcgctc caactagaaa ccgatgtgtc
    21361 atcgattagt catacccaat tgtctcgagc atttaatgca cttgaaccta aagtgttaga
    21421 agaaattttt caacaactgt tagaaaaagt tcaacatcaa atcaaaccaa ccaagcgaaa
    21481 tcatctgtat ctgattgatt ccagtacgtt ttcgcttagt ttaaaacgtc ataagtgggc
    21541 gactttccgt caaacaaaat caggtgtcaa gttacactta aactattgtt atatggacga
    21601 tactacgatg tatccaactg attttacctt aacaaatgcc catgaacatg atctcaatca
    21661 actaccagta ttggtgaatc aaccagaggc aacttacgtg tttgatcgtg ggtattagga
    21721 ctttgaaaag atggatcaga tgcattggga tggctatttc ttcgtcactc ggattaaaaa
    21781 aaacaccaaa gttcacgtga tagatactct ggaaacatcg ccagaaacag aaattctacg
    21841 agacgagctg gttcgtttag gatctaaaac ctatctaacc gccaatttcc gactagtcac
    21901 tgttcaagat aagaacggac gtgtgtttca atttatcacc aatcgaatgg acgtctcttc
    21961 aaaagaaatc tctgatatgt atcacgctcg ttggcaaatc gaattgtttt tcaagcacat
    22021 caaacaacac atgaccatta aaaccttctt ttctcaaagt gaaaaaggcg tgcagaatca
    22081 attgatttta acgatgattt ccgctctcct cacgtttctc atcaaattgg agacgaaaac
    22141 ggaaaaatca gtgttccaaa tcaaacgatt ctttcgttat ttactgtttc agccctttga
    22201 atgttgtcta gaaaaattaa ttcccacatg agaaaaaaga aatttggctc gttacttttg
    22261 gttttcagtt gaataacaga taaaaaattt tctggaaaaa gtcatcctct gcgtcagcac
    22321 agtttttttt gacttatttt cagaggaaat agttttcaga atattctaaa atgttttatg
    22381 caacactagt gatatttttt agaattagat ttctaatgtg cattttttga gtattaagga
    22441 gcaagtatac aaagatttat aaagctgatt aaatttgaat aaaaatatgc aggaacgcta
    22501 ctatttttag tagtgttctt ttttatattt gaataaaaaa tgtggtggtt aaatggtggt
    22561 tataacaaaa aatgaattaa tgaaattagg ttatgggaag tatcagtctg agagaatcat
    22621 acgacaggca aaagcaatta tggtttcaaa aagctatacc tattacgaaa atagaagatt
    22681 aggactagta cctgttgaat ctgtagaaga agttttaggt atgaagatag aggtagagga
    22741 ggattttcag aatcatggtt aattttaaaa aagataaaaa tgggaaatat cattttactg
    22801 ctagtttggg attcgacaaa cgaacaggga aaagagtaca aaaaaacgta gaggggttaa
    22861 aacagttaaa gaagaaaaaa agcgtatacc gaacttgttt ctaattatgg aaaagaagca
    22921 gaaacttctc aaagtactat gttgtttgag gagttttttt ataaattatt cctaccttat
    22981 tatcaaggga aagtagaaga aagaacatat aaaaatcggt tatctacaat caaaaaaact
    23041 tttcttattt ctttaaaatg gagttaagag aaatacgtcc aattgacatt caaaagtggc
    23101 aaaataattt attgagcaaa tataaaaatt cttatgtaag aaacatgtat gggatttttc
    23161 agatgtcatt agatcgagca gttgttttgg gactacttga aaaaaatcct gcaaaagtta
    23221 ttggaaatgt gaagaaaagg aaaactacag ttgatttttg gacaaaagaa gaatttacaa
    23281 aagttatttc aactttttat attgatgatt tgtaccaaca ttttggtttt atttgtatgt
    23341 ggttactttt tatgaccgtt atgcgtttgg gagaagccac tgcattaact tggaaagata
    23401 ttgattttga aaataaaaac ttgcgtgtga ataaaacact ctattataag agagccaaaa
    23461 cctatgagtt tgtagaaccc gaaacggctt ctagtattcg tacaatcgaa ctagacgaca
    23521 atacaattac ctttttaaaa gcttggaagg agcgtcaagt ttcaatagga ggcatgtcgt
    23581 ttgtactttc ttataatgga acacctactc agaaatatac aatccgtcat attatgagaa
    23641 gacatgcaac gatcgttggt gttcatataa tccgcataca cggattaagg catagtcatg
    23701 cttctttgct tatatcacaa taaaaagatg cacttcgaat taaagaaagg ttaaaacatg
    23761 ctgatgtaca aacgacttta ggaacttatg gtcatttgta tctaaattca ttgagagaga
    23821 taacaaatga tcccacagat tatatccaaa ctaatttttc taaaatcaaa ccgacaccta
    23881 tttacgataa taaaaaataa atgataaaca aaagtaggat cacaccaaaa gaaacacact
    23941 agaaaaacta taatacaggc ttttctagcg tgttgtttct tatttccgcc tatttataca
    24001 ttatactcat aaagcattta atgcatcgat cgtagccgca ttgtctatat gggtatataa
    24061 agttgttgta ttggtacttg aatgtcccaa ttgttgggca gttaatacca atgaatttgt
    24121 ctgttggtag agtctagtag ctaatgtatg acgcagtttg tgagggctga cttgaattct
    24181 aaagcctttt gaatattttg ctaccatccg ttcgattgca ataccggata tacgcttggc
    24241 ttctccttgg taaattgcta gaaataaagc tttttcgttt tctgttactt tatatcgttc
    24301 tttccgaata gctagataat tagctaaata ttccattgcg aatgctgcta tattgacagc
    24361 atctctttta tttccttttc tagttactac cacattattc ttatctaaag ataggtcatc
    24421 taaattaata tttataacct cggagagtct caatccagat cctaaaatca gtgcattgat
    24481 cgccaggtct ctttctacat ctcgttgata atagatcaaa gctcgtttac tcaaagtatt
    24541 tttatattca ttggcaatat aatctagata attttgtgta tccttatcta gaaataattt
    24601 tttctcaatg gcattggcac gtgcagctaa cgtagtttta tctgtgatgg ttgctacttg
    24661 atccatagga ttattgtcta agtatggttt tcctagagga ttattggaac ttttcgaaag
    24721 atatttaaat agaaccttta atgccgtgat atttctattg atagtagaag tagatagacc
    24781 taagttatta ttatctttga gcttagtttt tgttgtctct ttttttacat tttcttttgt
    24841 gcgacgtttc aaatgagatt tgtacaagtt taggtcatag gcagttaact gtcttatcga
    24901 ggtgatagaa gtatcaggaa cgatagactc actcagaagc cattcataaa agagcttata
    24961 attttttaga tattctaaag tggttcgagg tgattgatct ttatcctcac gatcttgaac
    25021 aaaatctttt atataatcgg gcatatgaag tatgattgta tctatttttt gatatatttc
    25081 tgtatttttc atgtcattca tcctttcaat aagtagggga gaagagtatc tctataattg
    25141 gactatacca attatagaat gttttgtcaa ttggtatgct ctaaaattta ttaatttgtt
    25201 tcaaaaaaag catataaaca ggtatacgtt taataattta aaataaatgg tatacataaa
    25261 tagggaagga aatagaaggg agcaatctaa attttttgaa ttttcttaat taattatata
    25321 gaaagaacaa tctttctata gagttagaca tgagagggac tatgcttgat ttaaaatcaa
    25381 caagcgtata tactgtatat acaaagaaaa aggagggaga agactatggc aattaaagaa
    25441 agaaaattta gggaagtggg gaactcagta gtattaacta tttcaaagga gtttcttaaa
    25501 gaaaatgggt taaatcccgg agatacggtt tttttagatg aagaaaaact tcgagcggca
    25561 attacaaaaa aacaagcctt atctgatgaa attgatttag caatatctca agcattaact
    25621 gaatatgata ctacttttag agagcttgtc gataaatgag tattcattac ctagaagcca
    25681 aagatattat aaaaatgaat gtaatccaaa taaaaaaata ctctcctaat gaaccccttg
    25741 gtgtaaagga tgcgaatgct ttagaaatgt gtgtagggca acttcgagcc tcagcttttg
    25801 gtgaagaggt ttatccttcg atttatgaaa aagcagctat cctacttata caattgataa
    25861 agaaacatcc ttttcacaat gcaaataaac gtactgcttt cttagctact tttgtctttt
    25921 tgaaaatcaa tggacagctt ttagctattg atcaaaaaga tgctgtaaat ttagcggtat
    25981 atattgctac gtatgataag gatttcgatc aactaaaata tgaagtgatc aacactataa
    26041 agacacatac gcagcccatt taaggagtta ctgtatgtgt ctttataggg ttattagctg
    26101 ctatagcgaa ataattgaag taaattacaa atagctataa ttcaaatcca actatataga
    26161 aaacgtaaat tttctatata cttggatatg ctggaatgtt taagagaata attacatttc
    26221 tagaaaatac aataaaaatt acaggataat tagccatatc ctacctcctc tagcagttgc
    26281 tcaaaagtta gcactaagta acttcttttt tgttgctggt aacaatttat caatactaaa
    26341 atagcgttta agtatctaat aaatactaat tttaaagctc ttaattatta tgaaacacga
    26401 tataacaata ttgctatatc gtgctattgt aatattatac atttgaagac agcgtattct
    26461 tgttctaata tcaggaattt tttataaata tcagtcatat taagactcaa aatttattgg
    26521 tatgttcctc tgtatagagt ttgaccgtct accattatat agcaattatt atcattgttg
    26581 tcttgcacca atataccgtt aagggtagca ctaggagtag taacaatcac tggaaactca
    26641 tgagaaagct cggtcatttt tcctgttctg ctagaatcgt gttctattgt caagccattt
    26701 actataaacg tgaatacttt acttcctatt gttatagtag ctttttgaga aacagtttct
    26761 gtagctggag ctgtgcttct ttccgaattt gttagggttt cactggattc attgctataa
    26821 acaattgtag aggattctac ggcttcttga gtgtccacgt tggtgctgct agcttcatct
    26881 agcttccttt tgtattgttc gttactgatt gctaagcttt cccgttggtc atcaagctta
    26941 ttcatttctg taatggtata aaataatcct cctgctagtg ctatattaac aactaaacta
    27001 accgcaaata ataccttttt cattcttcct tctcttcttt ctctttttgt aattccttac
    27061 ttttggatag gctacaatta actagacaga aaaattaagg tgtgtagact agaagaaaac
    27121 ataccaggag gaatttttat gtctaagaga acacgaagaa ctttttcaca agaattcaag
    27181 caacaaatcg tcaatcttta cttagatgga aagccacgtg tagaaatcat tcgagaatat
    27241 gaactaacgg cttcagcatt tgacaaatgg gtaaagcaat ctaaaacgag tggttcattc
    27301 aaagaaaaag ataatcttac gcctgaacaa aaagaattgt tagaactacg taaaagaaac
    27361 cagcaattag aaatggaaaa tgatatttta aagcaagcag cgctgatatt cggacgaaga
    27421 gacaagtaat cgatgcgaat aagcatcttt accctatatc agcgatgtgc agaatattag
    27481 gtctatcacg tcagtcctat tattat
//
LOCUS       DAYNVV010000035        27494 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.035, whole genome shotgun sequence.
ACCESSION   DAYNVV010000035 DAYNVV010000000
VERSION     DAYNVV010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.035"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(51..1517)
                     /locus_tag="ACGXWR_001674"
     CDS             complement(51..1517)
                     /locus_tag="ACGXWR_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HFK0803237.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1904..2500
                     /locus_tag="ACGXWR_001675"
     CDS             1904..2500
                     /locus_tag="ACGXWR_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFK0803238.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(2558..3040)
                     /locus_tag="ACGXWR_001676"
     CDS             complement(2558..3040)
                     /locus_tag="ACGXWR_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803239.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3146..3343)
                     /locus_tag="ACGXWR_001677"
     CDS             complement(3146..3343)
                     /locus_tag="ACGXWR_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803240.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3638..4396
                     /locus_tag="ACGXWR_001678"
     CDS             3638..4396
                     /locus_tag="ACGXWR_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFK0803241.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4456..4884
                     /locus_tag="ACGXWR_001679"
     CDS             4456..4884
                     /locus_tag="ACGXWR_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803242.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4930..5002
                     /locus_tag="ACGXWR_001680"
     tRNA            4930..5002
                     /locus_tag="ACGXWR_001680"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4963..4965,aa:Gln,seq:ctg)
     gene            complement(5152..5523)
                     /locus_tag="ACGXWR_001681"
     CDS             complement(5152..5523)
                     /locus_tag="ACGXWR_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFK0803243.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5738..5923
                     /locus_tag="ACGXWR_001682"
     CDS             5738..5923
                     /locus_tag="ACGXWR_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803244.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6006..6194)
                     /locus_tag="ACGXWR_001683"
     CDS             complement(6006..6194)
                     /locus_tag="ACGXWR_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803245.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6218..6481)
                     /locus_tag="ACGXWR_001684"
     CDS             complement(6218..6481)
                     /locus_tag="ACGXWR_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803246.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6639..6896
                     /locus_tag="ACGXWR_001685"
     CDS             6639..6896
                     /locus_tag="ACGXWR_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HFK0803247.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6967..7158)
                     /locus_tag="ACGXWR_001686"
     CDS             complement(6967..7158)
                     /locus_tag="ACGXWR_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803248.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7299..7619)
                     /locus_tag="ACGXWR_001687"
     CDS             complement(7299..7619)
                     /locus_tag="ACGXWR_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803249.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7642..8076)
                     /locus_tag="ACGXWR_001688"
     CDS             complement(7642..8076)
                     /locus_tag="ACGXWR_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFK0803250.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            8411..9049
                     /locus_tag="ACGXWR_001689"
     CDS             8411..9049
                     /locus_tag="ACGXWR_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFK0803251.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(9373..9456)
                     /locus_tag="ACGXWR_001690"
     tRNA            complement(9373..9456)
                     /locus_tag="ACGXWR_001690"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9420..9422),aa:Leu,seq:cag)
     gene            9984..10484
                     /locus_tag="ACGXWR_001691"
     CDS             9984..10484
                     /locus_tag="ACGXWR_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFK0803252.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(10674..11018)
                     /locus_tag="ACGXWR_001692"
     CDS             complement(10674..11018)
                     /locus_tag="ACGXWR_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HFK0803253.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(11172..12092)
                     /locus_tag="ACGXWR_001693"
     CDS             complement(11172..12092)
                     /locus_tag="ACGXWR_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFK0803254.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            12279..12770
                     /locus_tag="ACGXWR_001694"
     CDS             12279..12770
                     /locus_tag="ACGXWR_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HFK0803255.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(12794..15169)
                     /locus_tag="ACGXWR_001695"
     CDS             complement(12794..15169)
                     /locus_tag="ACGXWR_001695"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HFK0803256.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            15495..16121
                     /locus_tag="ACGXWR_001696"
     CDS             15495..16121
                     /locus_tag="ACGXWR_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFK0803257.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            16144..16848
                     /locus_tag="ACGXWR_001697"
     CDS             16144..16848
                     /locus_tag="ACGXWR_001697"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFK0803258.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            17040..17873
                     /locus_tag="ACGXWR_001698"
     CDS             17040..17873
                     /locus_tag="ACGXWR_001698"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFK0803259.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            18070..19998
                     /locus_tag="ACGXWR_001699"
     CDS             18070..19998
                     /locus_tag="ACGXWR_001699"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFK0803260.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            20136..20591
                     /locus_tag="ACGXWR_001700"
     CDS             20136..20591
                     /locus_tag="ACGXWR_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HFK0803261.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            20671..20799
                     /locus_tag="ACGXWR_001701"
     CDS             20671..20799
                     /locus_tag="ACGXWR_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803262.1"
                     /translation="MFEKLKYFIGTIGWFLLAVLLILGLAYLLFPDLIQNVFDTAF"
     gene            21061..21330
                     /locus_tag="ACGXWR_001702"
     CDS             21061..21330
                     /locus_tag="ACGXWR_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803263.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            21730..21984
                     /gene="rpsT"
                     /locus_tag="ACGXWR_001703"
     CDS             21730..21984
                     /gene="rpsT"
                     /locus_tag="ACGXWR_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HFK0803264.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(22073..23119)
                     /gene="holA"
                     /locus_tag="ACGXWR_001704"
     CDS             complement(22073..23119)
                     /gene="holA"
                     /locus_tag="ACGXWR_001704"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFK0803265.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(23157..25430)
                     /locus_tag="ACGXWR_001705"
     CDS             complement(23157..25430)
                     /locus_tag="ACGXWR_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HFK0803266.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            complement(25423..25962)
                     /locus_tag="ACGXWR_001706"
     CDS             complement(25423..25962)
                     /locus_tag="ACGXWR_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HFK0803267.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            complement(26098..26316)
                     /locus_tag="ACGXWR_001707"
     CDS             complement(26098..26316)
                     /locus_tag="ACGXWR_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HFK0803268.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            complement(26313..26558)
                     /locus_tag="ACGXWR_001708"
     CDS             complement(26313..26558)
                     /locus_tag="ACGXWR_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFK0803269.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            complement(26674..27402)
                     /locus_tag="ACGXWR_001709"
     CDS             complement(26674..27402)
                     /locus_tag="ACGXWR_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HFK0803270.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
BASE COUNT         8528 a         5353 c         4680 g         8933 t
ORIGIN      
        1 aaaaacagga actgctgcaa ataagcaatt cctgttttta tgttcattga ttaatgaata
       61 gagcccatta gttttttgat tggttctttc acagtaaata gcaagatacc accgacgatt
      121 gctactgcac cgataatacc gaagtaagca gattctgttc ccggtgtgta gaagcgtgca
      181 atttgtgcat tgattgcttg tgaagaagca tcagctaaga accaaatagc gattgtttgt
      241 gattcaaatg ctcgtggtgc taattttgtt gtcacagaca aaccaactgg tgaaagacac
      301 aattcagcaa taaccacgat gaagaaactt cccaacaacc acaatggact tacttttcca
      361 cttgtaccat aaagcatacc cggcaacatc aatagcaagt acgataatcc tgcaaataaa
      421 agtccaagag agaatttcac tactgtagat ggttgacgtt caccaagttt cgtccacatc
      481 gttacgaata ctggtgtcag aataaagatg aaaattggat tcaatgattg ataccagctt
      541 gcttggatcg ttacaccaaa tagcgtagat tgtgtacgtt cactagcaaa taaagctaag
      601 atagatgaac cttgttcttg taatgaccag aaaatgattg ctgcaaggaa taatgggata
      661 taagcccata ctcttggttt ttcttcagca gttacatctt ttgaagtcag cattttgata
      721 aagtaataca acggtaagat aatccccaat acactgattg tattgacaaa aaagtcaatt
      781 gtcagatgac cagttagttg tgccccgccg aatactgcag cgataacaac aagtgcgatg
      841 atcaagttac ggatgaatcc tttacgttct tcagttgtca aaggattcgg cggtgttgta
      901 cccactccgt ctaatgtctt gcgtccttgg atgatgtatt gtaataatcc aaagaacatc
      961 ccaatagcag ctaaagagaa ccctaaatga tagttatatt cttgaccgat tgtaccaacg
     1021 attagtggtg ctaataatgc ccctaagttg acacccatgt aaaaaatcga aaatcctgca
     1081 tctcttcgca agtcagtctt tgaataaaga tgtccgacca tgccagaaac atttggtttc
     1141 aaaaaggcgg ttccgataat aatcaatgcc atcgaaacaa acaatgtact tacaccaaat
     1201 ggtaaagcca agacgatgtg gccaagcata atgaaaactc caccgaagaa tacagtgcgt
     1261 tttgctccta acactcggtc agatacccat ccgccgacga tactagacat gtagatcaaa
     1321 gatccgtaga tcgacatgat agctaatgct gttgctcgtg gtaatccaag tcccccgttg
     1381 gcaactgtat cgtacatata atagataagt aatgcacgca taccgtaata actaaatcgt
     1441 tcccacatct cagtgaagaa caaagttgac aatcccttcg gctgcccgaa gaagcccttg
     1501 tcttgctgtt tttccataat ctatacccca attctttaaa ttttcagaaa atattataca
     1561 tctttaccga aaaatttaac taaaaaactt atttaagaaa tataaactaa ttttctataa
     1621 aagcaagtaa tttttaatgg caatatcata aaaaaaagaa gatagagatt taataattat
     1681 atatcagctg tttttttcaa ataagcaaaa attcctaaaa cacaacaatg aaagcgataa
     1741 ctaagaaaat ccttacataa cgatttttct tattaaaatt gttttttgaa cttcgcttat
     1801 tttttgtgag catatctgtt tacttacttt ttgtaaggtg ctatacttca tttcgtaatc
     1861 aattaaaaaa atgcaaaacg caaatcaaag gagaaatttt attatgacaa cttttactga
     1921 cactttgaaa aaccgccgtt caatctatca tctaggacgt aatgtttcac tttctaatga
     1981 agaattaaca actttgatca aagaagcaat taaagaaagc ccaactgctt tcaatgctca
     2041 atcaacacgc gcagttatcc ttttcggaga tgcacatgaa aaactttggg aaatcactga
     2101 agaagcactt cgcccattga ctccagcaga agctttccca aatacacaaa acaaattagc
     2161 tggtttcaaa aatggttatg gtacagtatt attcttcaaa gatactgacg tggtaaaagg
     2221 tctacaagaa caatttgaat tatatgcaga caacttccca gattggtcag aacaatcaaa
     2281 cggaatcgca acagctaata cttgggtagc attagttgat aaaggattgg gcgcaaactt
     2341 gcaacattac aacccagtta ttgacgaagc agttgcaaaa gaatggaata tcccttcaaa
     2401 ctggaaacta cgttcgcaat tagtattcgg ttcaccagaa acaccggctg gggaaaaaga
     2461 atacatgaac gatgccgatc gcttccgcgt atttggataa ttttatttga aataaaaaac
     2521 agaggttgtg acaaacatct tgtcgcaacc tctgttttta ttctggatca atcataatat
     2581 caatctctgc ctcatcgttt aagcgttggg acaaaaatgg aactaattct tctaatgatg
     2641 cagaaaattt cagcatcggt cctcgccatc cgtttcggaa aaaattcatt tttacgattt
     2701 tagaaccttt tggctgatat aatacaattt tattgatctc agaaaaagga acaccttttt
     2761 tgtcaaagct attcaaaaca agtccttctt ctgtgattcc tctactgtcc aacaaaaaac
     2821 taataaaaat cattgctgac aagatccctt ttgccaattc atctgctgta ggatgactga
     2881 tgagtgtata ccaaatgact agtgacacta agaagggtat caccaagtag acccatcgat
     2941 ttcgcacagt ccgataaata atttcttttc gaaccagcca aagaaataaa aacatcacaa
     3001 caacgaataa aaacaataga accgtaaaga atgttaccat gacaactcgc ctcgcttttt
     3061 cttctccaga aaataggaaa agaatactga tttaccttct caaagaaatt ggacttgcag
     3121 cacgccgcac gtccaattgt tttctttatt caaatgtatc atattttgca acaaccatgc
     3181 ttgctttttc atctaataat tcttggtcct ctgcagcaca ttgggcaact ttgaccacgg
     3241 cgcagtttgt catttttgat acaacttcac caatgaccgt ttttgtaaaa ccaattggtt
     3301 tgcatgcata ttgttctcct aaattaatca tttcttccgt catcaaaatc ctcctaaact
     3361 gctggaactt ttctccacat taccactgct atttctttgg agatttaact cattgatttt
     3421 tatttacagt taaaaatcaa ccttacaggc attatagcgt actgttttcg ttttcacaat
     3481 taaaacagct gttgtattta gaagaatttt tttcaaaaaa ttaaaacata ttccttaaaa
     3541 actaattatt tcctacatat taaaatataa tacttccatt tccaataaaa atacatttat
     3601 aataggaaag ataaacagct gaaaagggag atttcaaatg aagaaaaaaa cgttcaaaaa
     3661 actattgttt ctagggggca cagctgctct tttattaagc ggtacaagtt attacctaca
     3721 tatccattct ccagaacata caatgaacac tgcacaaaaa agttcaacac aaaaaacgaa
     3781 aaagacaaaa gagaaagcag aagttttact agatgttcca ttagagagcc agtttgattc
     3841 tccttcttta gaaaatggct gtgaagtcac ttcgctttct atgcttttat ctttttatgg
     3901 ttatgaaaca actaaaaacc agttagctga gcaattggat tacgtccctg ttttcaatgc
     3961 agatgggact catggcgatc ctaatgaagg atttgttggt gatatcagtg gcggagactg
     4021 ggctatggtc gtctatgttc ccccagttgc ctcccttgct cagcaaatcg tccaaacgga
     4081 ttatcacact tttccaaaaa ccgatgctca actcgatgat atcaaaaaag cactatctaa
     4141 aggaaatcct gtctggactt ctgtgactat caattttgaa gtcccagatg aaactgattt
     4201 tatgacttgg accacaaata atggagaagt aagagtcact cctcttgttc atgcttgtgt
     4261 agtcactgga tatgacaaag aaaatattta tgtcaacgat ccctatggtg taaaaaatcg
     4321 agcagtaccg atcaacgatt tttcggcgat tttcactgca atgggtggac agatgctaac
     4381 tttggagaaa agctagtaat tcaaacaaaa atcccttata ctcaagatac caaacctttg
     4441 aagggagcgt agataatgga aaaattcaca cataaaaaaa tggatccaaa tgaaattccg
     4501 attatttttg tccgtgactg caagggaaat gttcaaggta aagtctctat taatgagtgg
     4561 aacgagcgtc gcagacctgc taccctcaat gaactggaaa tcaaattgta tcgtcaatct
     4621 cttgtttatt acgcagatca agagtacgag aaagccaccg atttattgaa atttctaatt
     4681 gctcgaacag agtatactcg ctttgaatat attgaacgtt tagcaaacat ctatcatatt
     4741 atgaatgaac ctgtcaaaga atatcagtta ttggacaccg tcttgtcagt agcagaactg
     4801 attgcccttc ctgctggatt agaaaagaaa ctagtacgcc gccttttacg agtaaagcaa
     4861 caactatccg atcaagaaaa ataacttgcg tttttttagg aaagtgctat gattattttg
     4921 ttgaataaat gggatgtagc caaactggta aggcacttga ctctgaatca agcaattgta
     4981 ggttcgaacc ctgccatccc aatttgatgt gcttgctgaa aaaatgaacc ccctgtaaaa
     5041 gaacaatctt tttgcagggg gattattgta ttatttttac tacttgtatt tagtttacat
     5101 aattaaatta tgaataataa aatcgggcgt attcttaata caaaaactga tttacccaat
     5161 aattgctaat gctttctccg gaactttttc tctaggaact tcctcatacg tttctatgtg
     5221 tgctccttta ttgctaattt tcaaataatg attttctttt aacacagaaa gaccattaaa
     5281 ttcaaccgtt cgttctttcc cattggcatc agcagctttc tgcacatacc ttgctgtacc
     5341 atattcattt acttcctctg gtttttgtgt ctttacatag acctctcctt tttcaactaa
     5401 tggatttagc tgatcaagta taccagggat ttctccataa cttccttcag tataatattt
     5461 cagtccaaat agcaaaatac cactaatcgc cgccagtcca atcaaatatt taatcacttt
     5521 catctttcta cctccttgtt atatattcag tatatgggtc agttaaagaa attccatccg
     5581 tcccaagttg gagatttttc tcctacttta gaagcgagaa tcgagtgttt ttttagtaaa
     5641 aatgatcgtt atttgatatt attgacgtgt ggataaatca gtttttctcg ttttgtccat
     5701 gtaaaaaatc atgttgatag caaaggatgt gttcaaaatg aatcaagaag aattatttca
     5761 aaaagtcaag gaaatgatta agaacggcaa tttcgatggc gcaaaacgat ttatcgaaga
     5821 acataaagaa caattaggac cttataaaga gaaagcccaa aatcttttaa aagatgtaaa
     5881 tatcgacagt gtcaaaaaca aatttaaaaa tctattcaaa taagtaaaac tttcactttt
     5941 gtaaaatcaa aggaggacaa tgctgctgca tcgtcctcct ttggttcttt tctgaatact
     6001 tcatactaaa ataaacgtgt cggatcgtaa tgataagtca cattgccgtt cagtgaggct
     6061 tttcccacca catatttacg attctccaac ttcagccacg cttctcgaaa agccattaat
     6121 tcttctcttt ttacatcaat cttttcgatt tttccatcga tcaaatcttg aataagttgt
     6181 tcatatggat tcattttttt cctccatctg ctgtcaatca ataagttgta aaaataggtt
     6241 catatgcttt tttggtatct agatcttctc tgactttgac tgtcgtataa ataatttttt
     6301 ctactgggat actataataa cttccttcac cattattgaa tcggtgaacg tctttctttg
     6361 ctaaaatacc atttatttta ttcgtcagta cacgttgttc gacactgtta cttacaacat
     6421 agtaaatcac ccgaatatta ttgatcaaat gcaaatcgat ttctaacact acatgatcca
     6481 tgaaaatccc actccttctt tcactttgat tatagcaagt ttctcctcta atttcaaaat
     6541 cgatacagat tttaccggat aaatccacaa aactgcttgc gccatttcgc acaaagtgtt
     6601 attttgtatc atggacttta tttatcggag gcaatagtat gatcgcgatc ggtcaatttg
     6661 ttttttatat tccttttttt attatgataa gcattctttt ctattacata aaatggacaa
     6721 aaaagaagtt ttcagtttta ctggcctctt tacctgctgt atattttact tatcaaattt
     6781 tttcttttag gcattgggaa acaacgtctg tattaataac acacatcatc gaattgacgc
     6841 tttcagtaat ttttcttatt atttggatct attttttata taagaatcag aattgaatcc
     6901 ctcgcatgtt taaaaagaaa acgattaaag atgcagcaaa tttctgccga tctttaatcg
     6961 ttttttctat tctgttatac caaaaaaatg tttgaatcgg tgaaggatcg ttccttgttt
     7021 taattctata aattcttgtg cgatcgggta cttttcttcc aaattttctt tgttcttttc
     7081 gatcaggctt ttcgcttctt catatttttt atctgcacat agtgctttta cttcctgtaa
     7141 tacttttcct gcttccattt gcctcaccct cttgccattt tattgcttta agttttattt
     7201 aagttatacg cattattcta gtttcatccc aaataacctt ttttcatttt tactcctcga
     7261 actaatcagt tttctaaagg ctgattggtt cgtctttttt atttttcctc catttcattc
     7321 tgctcttctg ttaatttatc taatgctttg attgatgctg cggctcttgc ataatcatag
     7381 ctgtataatt ccataaattt atcaggcaga acaaaccacg ctggatgata accgttagct
     7441 gtgacaggga atcctttatc ttgttggtta tctccatccc atctcagagc aacacctttt
     7501 tttcctttcc actttactaa agcgatcgag tatcccttct ttgtttgtgt gccgtcttca
     7561 ataattgcta aaatttctat tttttctttt ggcgcacgga cttcttgagg acgaaccatt
     7621 ttctattcct cccttatctc attacttcac gaccaacaca ctgcaagggg catgtgatac
     7681 gacataagaa gcggtcgatc caactaatgc ttgttgtata gcaccttttc ctgtcgctcc
     7741 cataacgatc aaatcaatat tttcttgtcc agggatgaca ttggcaatca aatttcttgg
     7801 atctccagtt tcaactattg cgtggatctc agcaatgccg tactctttgg catcattgat
     7861 ttttttcagc atggctactt ctgttctttg tttttcatct gcatagattt ttgaaaaggc
     7921 ataggcacta tgggtcagct caactttgtt gatgattgac acgataaata agtgggcttc
     7981 attgtccttt gctaagtcaa gggcttcagc gaacgctttg atcgattgtc ttgatccgtc
     8041 aactgctacc atgatgttct ggtatctttt actcattgga accgcctcct ttttctttta
     8101 ttgtaacatc tcaagcaaaa atacaaaaaa tatacgcaat atgtaaataa aatgatgaac
     8161 aaaagcaatt tctttcaagt tatttataca tttcttttct catcagaaca cctgttctaa
     8221 tcccattatt tctgcattat gtgaaattcc tcatcatttt tcacatcgag cgaacatcat
     8281 tctgttacaa aaaacgtgga tttgtcataa attgtcatgc ttcttttacc tatgaaatat
     8341 tttcacgtgt taaagtattc ctcgttgaac acaacaaata aaacttttta acgaataaag
     8401 gagatttttc atgacatcac ttaaaacttt actttttgga acaactttgg ctgccggcgc
     8461 tgcattcttc atgggaacga ctgctcatgc ggacgaagct tataccgttc aatcaggtga
     8521 tactctatca acgatttctc aaaaatacgt tggtgataac tccttgatca atgccattgc
     8581 agaatcaaat tcaatttctg atattaacct gatctactca ggacaacaat taacaatccc
     8641 aacagaaggc tctgcacaag cagctgctga acctcaagca gccgttcaag aagcaccagt
     8701 ccaagctgaa cctgttcaag ctgaacaacc tgttgtacaa gaaacggttc aaacggaaac
     8761 acaagcagcg cctgttgctg aaacacaacc tgctcctgct gtaacagaaa ctgctgctac
     8821 tccagcaagt acaagctctg caaaagaatg gatcgcacaa aaagaatcaa gcggttctta
     8881 cacagcaacg aacggacgtt acatcggccg ttaccaatta gattcttctt acttaaatgg
     8941 tgactactct gctgcaaacc aagaaagagt agcagaacaa tatgttactt cacgttatgg
     9001 ttcttgggaa gcggcgaaag cattctggga agcaaacggt tggtactaag attcattatt
     9061 tgaacgttta aacacattca aaatatagta agaggtcatg cgatttattc tttcgcatga
     9121 cctctttttg agtttaagtt tagtctttat tccttaacta tcgtttgcca gtatttcttg
     9181 tatcagaatc tataaatcta ctatttgaat caatctatta ggttttaaac tgtcccacct
     9241 tcacacaaat tttttttgat ttatttgaat ctggttccgt tgtttaaaat ttttcctata
     9301 ttcttttaga taatatgtta ttttctttct catcgctcca ggtgtacctt ctctttataa
     9361 aaaaacaaat tatgcggcta agaagactcg aacttccacg aggtcaccct cactagcgcc
     9421 tgaagctagc gcgtctgcca attccgccat agccgcatca catcttttag tttaggatta
     9481 catgtgtttt ttgtcaagaa catatttttg ttctttttca tttctgtacg ccctccctta
     9541 tgccatctac acaaataatt catccgagca actccatcat ctattgaggg ttggtgaaaa
     9601 aatctgtttt atccatatga tcgatttcaa tgttaaacga acgactctgg gattagtaac
     9661 tattttattt ttttcttcat ttcttttttc ctctttttct cgattcagct atcttctttc
     9721 atttggatat tgattatttc ttctgttgat tactatcctt ctggaattct agacgctgaa
     9781 gtaattcacg ttttctttct tctagagatc ataagtaacg aatgaacgaa cttcaaataa
     9841 tttttttatt gtaattcata tttgtattgt tcgatgattc ttaatacgat atgacacaat
     9901 aaataaaaat aggcatggct atttacaaca atagtgctat agtagaaaac aaatgaataa
     9961 ggttacttaa agaggtgaat acgatgaaac tgatcaaact atgggaagca gatttaaaga
    10021 aagcttatca gctacaaact agctttggac caaatgagag tggatttatc aacaatgctt
    10081 atggctatac atttgctgaa tttttagatt atgtaaaaaa atgcgaaaaa acgtctttag
    10141 gaatcgatct tcctgagagt tacgttcccg caaccgtctt tattttagaa agtgatgaac
    10201 atgagtatgt aggaattttt aatttgcgcc ataaactgaa cgaaacatta agaaacggcg
    10261 ctggccatat tggttacggc atctccccta attatcgtaa aaaaggatat gccacacaag
    10321 gattagcatt agtactacaa gaggcaaaaa aaatcggcat tgatgaggca cttttgtctg
    10381 taaataaaaa aaatcttggc agtcttaaag cacaacaaaa aaatggggct gcgatttatc
    10441 gtgaagatga gaaagaatac tatacgaaaa tcaaactgat gtaaaaaaga aggattccaa
    10501 aaggaaaggg atttgaatgt cctttatcaa tagaacacat ttatttaatt aacttataat
    10561 atagcagaca aaattttata aacaaagaaa ccttttatct cttttcttct agaaaggata
    10621 aaaggctttt ttgtttttcc tatttgcttc tcatagctag tcagccaaga tttctatcgt
    10681 atccccaacg caatccgtgc ataacggctc atcttatctg tcgtccatgc tggataccag
    10741 actagtttga cttctgcttt cgttacttct ggcacttctt ttaatgcgtc atggatagat
    10801 tctgttaaaa tatctgctaa tggacagccc atagttgtta gagtcatctt aatgactgtt
    10861 tctccatttt caggattgaa ttctatatca taaatcaagc ctaaattgac gatgtcgatt
    10921 cctaattcag gatcaatcac catttccaag gcagcaagaa tacgttcttt gattagttct
    10981 atttcttgtc cagaccgttc ttggtttgct tcgctcatcg tacgacactc cttaacacga
    11041 tttttattta tcatactctt tttttagctg cttgtaaatg agaatttaga agtaagattc
    11101 tcgtttaaat ttataaaaat gttcttatta gatgtaatag attaaattta ttctaaaata
    11161 aacctgattc ctcatttttt ttgtgaacga ttttttattt ctggcaatac gccagttgtt
    11221 cgatacattt tttgttcgtt ttcatttgca aaccggccaa atactgaatg agttggtaaa
    11281 atattgataa atgcatcgtc gtcgatttca tgaacgatct gatcaagatc atacatttcg
    11341 tagcgggtga tgaccatcat gatcatgttc ccttgttttt ttgaatagcc accgacagac
    11401 ggcagtaatg tcattccacg taccatccgt tttgctagtt cttctgttac ctcttctggc
    11461 ttgacggtaa cgatcattgc tgttactttt tgatgactcg tgtggatggc atcaattact
    11521 tgagtcattg cataaatgga aataatcgta tacaaggcac tttcccagtt aaagaagaag
    11581 cctgcgatga ctacaatgat accatttaga atcagcatgt agtttccgac tgtttttcca
    11641 gttgtttgtg aaagtacaag agagatgata tccatcccac cagttgtaaa gcccattttt
    11701 aaagataatc ctacgccaag acctaataaa acaccgccta ctagggcatt catcaaaata
    11761 ttatcagtga tctgtccgac tggaagcagc atcgtcatca ccgatacaca tacaacattc
    11821 acaaaactaa ggatcgttgc tcgttttcct actttgagaa accctaatac aaacacaggg
    11881 atattcaaaa gaaaaataaa tgttcctgtg tctatcttga tatgaaacca ttcatataaa
    11941 agcgaggaaa tgatttgagc gatcccattc atccctgcag aaaagacatt ggctggaatc
    12001 aaaaaataat ttaaagcgac cgcagcggtc aatccggtta tcaaaataac cactattttc
    12061 tttaatcttt catttttatg atacgcagtc ataattttac tcacaagcac ctctccccta
    12121 ctttggtatt ccaaatgtaa gaataacagt ttatctatta aaataaaata cttcgaactc
    12181 aaatgagaag aattttagca aacaggtaag aatctgccct aatcctatga taagatagat
    12241 gtatggtaaa tatttatatg tatatcagga gggttcctat ggcaaaagat gctagcttcg
    12301 acattgtatc agaagtcaat acagaagaag taaaaaatgc gattcagcaa acaacaaaag
    12361 aattgtccaa tcgctttgac ttcaaggatt ctacagtaga aatcaaatta gagaacagca
    12421 atctagttgt attgagcgat gatgatttca aaatcgaaca gatcaaagat gtattatttg
    12481 gtaagctgat caaaagaaat gtgccaatca aaaatatcca tttttccgaa tcagaacacg
    12541 ctctaggtgg caaagctcga caaactgccg atttggtcaa cggaatcgat cgtgaaaacg
    12601 cgaagaaaat cactacagct atcaaaaatg aaaaactgaa agtaaaagca caaatccaag
    12661 aagatcagat tagagtgaca ggtaagaacc gtgatgatct acaagctgtg attgctttat
    12721 tacgtaaact tgacttacca atcgagttgc aattcactaa ctatcgttaa tcaaaaaacg
    12781 aggctgacgt ctgtcattcc tcgttttttt gatttactgc ttcttttgat aaccaaaaac
    12841 gctgtattcc ttcttccaat tccccaacac ttcgtacttc tcttgctgtt tgccaatgtt
    12901 gtgggaataa acgtcgataa gaaaaactag aaaatcgttg atctgccaat acaacgattc
    12961 cttgatccgc catgccacga atcactcgac caccagcttg caagactttg ttcattccag
    13021 gaagctgata agcgtaagca aatccaaggt gttccttctc atcataatat gatttgatca
    13081 gttcctgctc atgattcatc tgcggcaaac ctacacctac gatcatactg ccgatcaatc
    13141 ggtcccctct caaatcgatt ccttctgaaa aaatcccgcc aagtacgcaa aatccaatca
    13201 atgtttcagc gggatttgtt tgaaattttg ttaaaaatcg ttcgcgttct tcctcattca
    13261 tgtccgtttc ttggattagc acattgctgt cgggatattg ctgtctgaat gcttccaccg
    13321 caagatctaa atattgataa gaaggaaaga aaacgaaata attcccgacc tttccatcag
    13381 caaaagcatg aatcgtctct actaattttg ccagactgtg ttcccttttt cgataagtcg
    13441 tctctaggta atttgcgatg aaaacttgct ggtttccttc tgggaaagga ctcggcagtt
    13501 tgtaagccag acttttttgt ccccccagtg tttcctgata ataagagagt ggtgaaaaac
    13561 tagcagaaaa aagaatactg ctttttcctt tatccaacga ctgctcaaga aacaagcttg
    13621 gatcaataca aaactctttt actatcagat cgcgatacgt tttttcgact gttgtttcgt
    13681 agtgatcatc ataaaattca ctgaccttca aaaaatgaag caaatcaaaa taataaggaa
    13741 gcaattgttc ttgtgatggg tgctcaggaa attctgccag ccattcttta attttttcgc
    13801 ttaattgata acctgccttt actaaagatt cagccggtgc tttttgatga tgataatccc
    13861 aatgatcttc ttttgctatt tctcggatcg aatcaaattc ttttaatagt ttgttgaaac
    13921 ggcgatgaag ttttttgaat tcctttggta tagcttcctt acttcgtttc gttttttcat
    13981 aagatagttc tgccgaatac atctctcggg aacgattcac caaattatgt gcttcgtcaa
    14041 tcaaaaacag atagtcctcg tttttttcat cttcaaaaaa acgtcttaaa taaacagttg
    14101 gatcaaataa ataattgtaa tccccaatga ttacgtcaca ccagatactg acatctaatg
    14161 atagttcgaa aggacaaagt gtatgctttc ttgcataagt ttcgatgact tcacgagtga
    14221 tctgattctc atgattcaaa agatcccata aaccttcatt aatccgattg taataaccat
    14281 tggcatatgg gcactgatct ggattacagg tcgtctcatc taaaaagcag atcttgtctt
    14341 tcgccgtcaa agtgacactt tttacttcag ctcctgtatc ttttaatgct gtcatagcat
    14401 cttcagctac ttgtctagtt attgttttag ccgttagata aaagatcttt tctccctctt
    14461 cttcccctac agctttcaaa gcggggaata acgtagagat tgtttttcct gttccggtag
    14521 gtgcttctac aaacaatttc tgtttcgtac ggatcgtttt ataagcagct accgctagtt
    14581 cacgctgacc tttcctatac tcatcatggg ggaatttcaa agccatcaaa gaggcattgc
    14641 gtacagtgcg ccagttttct tgaaaaacaa gccattcttt ataatcttca gtcagctttt
    14701 taaaaaaagt ttctaactgc tctcttgtct gatgttcaac ctttctcgtg atcacttctt
    14761 ctgccgtctg gaagtaagtc aattgcagat ttatttcttg taaatcatgt tcttgactat
    14821 agatataggc atacaccctt gcttgatgaa agaaaagttc cacttgttct ggttctaaat
    14881 cttcaaatcg tggttcggag gttttgattt catctatata ataaataccg tctcttttga
    14941 aaataccgtc tgcacggcct tcaacgatca ggtaatattc atctaattga actgttgttt
    15001 ttaaaaagac ttctttttca tagttttctc ccgcatcttt ttggagcttg cggtggattc
    15061 tcgctccttc taatgcagta tggttacttt ttttacgatt gtcgatactt ccacgtcgca
    15121 aaataaattc tactaagtgc cgcacagata tttttgactg tttgatcatt tccaccacct
    15181 ctttctctct aagattacct gaaaaaacct agtttagcaa aaagagctct ctttccaaac
    15241 ataaaaaaac accctgctga ttaggcaggg atataggata tagaatttgg atttttggat
    15301 gaatctaatg taacaaggac atattaaaat gctatgaaaa cttactttcc ttctctttag
    15361 aatatccaaa tacttttcat atagtctgat aattcagata agtaaagaga aataagtacc
    15421 tgtttttgtt tcctagcaat gaatgcgtta tactaatgga tgaaagaagt tttggctatc
    15481 aaggaggaat gcacatgcat atcgaaagat taaaaacagg aatgattgaa gaaaactgtt
    15541 atttggtcta caacgaagaa gcacttttga tcattgaccc tggagaagat gcggaacgaa
    15601 tcaaacaaga aatcaaaaaa acaaaccaac agccggtagc gattttgctt acccatactc
    15661 actacgatca tatcggtgca gtggaacctt tacgcgcgta ttatcaaatc ccagtttatg
    15721 tcagcccact agagcaaaaa tggctaggtg atccgatttt gaatctttct ggactcggta
    15781 gacatgatga tattgctgat gttattgtct cgcctgcaga atatgaattt gaaatgaaaa
    15841 cttatacttt aggaaacatg tcttttcgcg tcgtccctac cccagggcat tctataggaa
    15901 gcgtcagctt tatttttgat gattttgtcg tttctggcga cgccctgttt agaggaagta
    15961 tcggtagaac cgatctgtat acagggaatt tagaacaatt acttcatagt attcggaccc
    16021 agctgtttgt attacctgat gaatttgcag tctatccagg acatggcgat gcaacgacga
    16081 ttgaacagga aaaaaggaca aatccttttt tcaatcgtta aaacgactta ggaggagaat
    16141 aaaatgacag aaactacact ttatatcgta cgacacggaa aaacgatgtt caatacaatt
    16201 gaacgagtac aaggctggtg tgatacaccc ctcacaaagc aaggacaaga aggcattcat
    16261 tatttaggtc gcgggttaaa aaatgtcgac ttttcatttg cttattctag tgacagtggt
    16321 cgtgcaatcg aaactgcccg tattattcta ggagaacatt ctaagggaaa agaaattcct
    16381 tattttattg aaaaaaggat tagagaatgg tgtttcgggt ctcttgaagg tggatatgac
    16441 atggaaatgt ggggtgtgat ccctcgtgta ttgaatttta aaacatatga tgaaatgttt
    16501 accacagaag tttcttttga acaaattgct aatgctgtat acaacttaga taccgctggg
    16561 tgggcggaaa cttatgaaac attgcgagac cgtgtatgga caggatttga agatatcgcc
    16621 catcactgcg aaaaaaatgg tggtggaaat gttttagtcg tatctcatgg tttgacgatc
    16681 gcctttttgc ttaatctgat cgatcctaaa cagcctgttc gtgctgggct tttaaatggc
    16741 agcgtaacaa aggtcactta tgcaaacggt cgattttcta tccacggcat caatgatacg
    16801 tcttatatcg ataacgggaa aacacatagt cgcgactcgt ttctataatg gggatatttt
    16861 aatttttacc agagaatcat aaaaggcaaa gtctgaacga gggctttgtc ttcttttttc
    16921 tcttcgtgta cttatctgct ttatttctca agtttttctt aatattaaaa aacagattgg
    16981 gtttctcaaa aaataacggt atactataag atgtatctta attgggaagg aaggaattta
    17041 tgttttttgc aaatattatc aaagcagtga ttctcggtat tattgaagga ataacggaat
    17101 ggctgcccat cagtagtact ggtcatttga tcctagcaga tgaattcatc aaactggatg
    17161 ccagttcaca atttatgtcg atgttcaatg tcgttatcca attaggggcg atcttggctg
    17221 tcgtcgttct ttattttcac aagttaaacc cattttctcc aagtaaatca acggtagaaa
    17281 aaaaagatac gtggacactt tggtttaaag tgatcgttgc ttgcatacca gccatcatca
    17341 ttggtttgcc tttggatgat tggttagaag caaatttcca caagttctta ccagttgcca
    17401 ttgttttgat cgtttacggt attgccttta ttattgtcga aaaacgcaac aaaaacaaaa
    17461 cacctcgttg gacttctctg aatgacttta cgtaccaagc agctcttctt gttgggttat
    17521 tccaagtctt ggcacttgtt cccggaacat cccgttctgg cgcaacgatc ctaggatcta
    17581 tcttgattgg tgcttcgcgt tttgtcgcta cagagttttc atttttctta gggattcctg
    17641 tcatgtttgg cgcaagcggc ttgaagatcg tcaaatattt agctgaaggg aattcattca
    17701 aaatggaaga aactgttgtt cttcttgtag gaacattcgt atcttttgtg gtttccgtct
    17761 tagctatcaa attcttacta agctatttga agaaaaacga ctttaccgct tttggctggt
    17821 atcgtattat ccttggtatc attttgattg gttattggtt tattgcaatg tagaaaaaac
    17881 cagaacactt ctcttatttg agaaatgttc tggtttttta ttttctttaa taataatcat
    17941 tataaataat aaaaacaaca tcaagcttaa tcaccaaatg ataaccatta tcgttctcat
    18001 ttagctgtta ttattatcaa ttacattttt attatgctat ccttgttttg acaaggaggt
    18061 ctaataacga tgactaatca gaaaaaagct tttgcagcaa caatcggctg ccttttattt
    18121 atgatcttcg gttttatctt cgaccgattc tctcttacca tcaccccact tttttatatc
    18181 agtgccatta tcatcggtgg atataaacaa acatcggaag gcttgaaaga attgtggaat
    18241 gatcggacac tgaatgtgga tttattgatg gctttagctg ctattggtgc ctgtttgatc
    18301 ggtaattact ttgaaggagc aatgttgaca ttcatctttt gtttaagcgg tgcattagag
    18361 gaatacacaa ctaataaaag tcaaaaagaa attactgctt tgatgaatct tcaaccacaa
    18421 aaagcccaat tattaaaaga aaatggacaa atgcaagaag tagatgtttc tcaactaaag
    18481 gtggataact tggtatttgt cgctaaagga gcagctgttc cgatagatgg ctttttagaa
    18541 agcacacagg caacgatcga tgagtctgca ttaagcggtg aatctgtgcc tgtagaaaaa
    18601 tatttaggcg atgagatgta tgcaggaacg ctgaatcaag gaaatcccat cacgattcga
    18661 gtaacaaaaa cgagttccga aactgtcttt gctaagatta tccaattagt agaagaagcg
    18721 cagaatacgc caactcaaac agcttcattt atcgaacgaa tcgaaaataa ttatgtaaaa
    18781 ttgattttgc ttgctgttcc tctaatgatc cttctccccc actttttcct aggttggagt
    18841 tgggatgaaa gcttttatcg aggaatggta ttattagttg tggcttctcc ttgtgcgctt
    18901 gtcgcatctg ctacaccagc ttctctagct gctctttcaa attctgcaaa aaatgggatt
    18961 ttaatcaaag gcggtatcca tttagaaaag ctttctgaat taaaagcgat tgcctttgat
    19021 aaaacaggaa cgctcactaa aggaaaacca gttgtaactg acagcttttt ctttgatgaa
    19081 aaggatttgg cacaacaact tcttgttgct atggaacaaa aaacgacgca tccacttgct
    19141 catgcgattt tgcaatattt cgattgcaca atacctgaag aaatccaata cttaccaata
    19201 gaagaaatta ctggttttgg attacaaact acctatttag gtgcgcaatg gaaagttggc
    19261 aagcacgcat atgatcctga gacgatgata atcagcaaag agattgcgga aatgatcgaa
    19321 cgtttggaaa atcaaggcaa aaccgtgatt tatctttcta aagatcagca gttaattgct
    19381 gttttaggtc tgctagatat tccaaaagca aatacccaac aagtaatttc ctactttaaa
    19441 tcccaaaaca tccatacaag tatgataacc ggcgaccatt ctggcacagc aaaggccatt
    19501 gctgaacaag tagggattga acattactat gcaagctgta ctccggaaga aaaaacacaa
    19561 ctagtcaaaa aagagaatga actttaccaa gtaaatgcga tggttggtga tggagtcaat
    19621 gatgcgcctg ctttagcagc cgcttcttta ggtgtcgcta tggggcaagg gacagatgcc
    19681 gctatggata tcgcagacat cgtcttaatg aaaagcgact taaataaatt tgtctacagt
    19741 catcggctat ctttaaaaat gcggcggatc atcaaacaaa atattatttt ttcgattctt
    19801 gttattctct tgttgattgc ttctaacttc ctgcaatttt taaatctacc tcttggagtt
    19861 gtaggacacg aaggaagcac aatattggtt attctgaatg gcttgcgttt actaagacct
    19921 ttacctgatc tttctgattc ttcaaaaaaa tgtaagtctt gtccactata caaagcgcgg
    19981 ctgtcttctg tcaaataagc aaagtgtttt tttatgattt tgtttatttt atgaaaaaaa
    20041 cagcttatga ataggtcttg aaggatgaat tcctactttt gtaactttct aaaaacatgt
    20101 tatgattgtt tcgaagaaag tgaggaatat atttcatgga aagttggctt tttttaggaa
    20161 ttattttact tgtagcaatt ttagctaaaa atcaaagtct gatgatagcg gcagcttttg
    20221 ttttgattat gaagctcata ccagcctccc gttccttttt cccttggctt caaggcaaag
    20281 gaatcaatat tggggtgacg atcatcacag cggctattct aatccctatc gcaacaggag
    20341 aaatcggtct acgtgatcta ttagaagcct ttaaatcccc tattggctgg gtagctgttt
    20401 tttgcggtgg gctagtggct gtcttatctt ccaagggtgt aggattgatt gcttctgatc
    20461 cacaaatcac tgttgcactt gttttcggca cgattttagg tgttgtcttc ttaagaggaa
    20521 tcgccgccgg accggtcatt gcttctggta tcacttactg tatcttacaa gtatttgctt
    20581 taggaaaata gaacaaattt tgtctatttt aggagattct taacaccccc aatttactga
    20641 tccgtgatat actgacaacg aggtgataca atgttcgaaa aattaaagta tttcatagga
    20701 acaatcggct ggtttcttct agcggtactt ttgattctgg gcttagctta tctattattt
    20761 cctgatttga tacaaaatgt gtttgatact gctttttgat tgacctatta aaacgatata
    20821 ggggatgctc ctgcgatgca ggggcttttt ttaatcaatg ttttgtaata atttaggccg
    20881 tgccaatgag acttcctata gaattcgatg ctcttttttc tttttggctc ttctgctctt
    20941 ttttgttata ctagattaca gtggacaaaa gaaagaatga tcgcatccac ttcaacgaat
    21001 atcaaaatgg aagaattagt gcctgttttc aggttacttt gaaaagaaag gaagacgctt
    21061 gtggaaactt ttgaaggtct tttaattgat acgtacgttt tacaagaaca gccaatgatg
    21121 ctgactggga tcaacttgca gcttgaggac cgtgtgatca atggcctgct taaagatcgc
    21181 tatttggcaa aatatatctt acgtttgccc ctaaataaat atgtgctgga agtaagtggc
    21241 aaatggaacc gtcggaacca gttggtcata aaaaaaatgt tgataaaaaa tatcgatgaa
    21301 tacattaaaa taatcggtac accagaatag cctttactga tcaaaggata ctggttataa
    21361 aataactgca gtttcttaat agaaaaacaa agaacaacag ggaatcgtat cccttttcaa
    21421 aaaaaacttt gcaaacggtt ctctttgtta tataataact tagtaccaaa cattcccatt
    21481 caaactttgt ttaaatagat aaataaaaat ctagtttggt ttgacgctat tgcctcccac
    21541 aatagcgtct ttttgatttt tttcagcttg tactatccgt ttttactgaa aaaaaatcct
    21601 aataaaagac tgttaaggaa aaaaacttgt catgttcata ttgcaaagca cgctgccttt
    21661 aggtataata atgaatgttg aattatgcgg taacacgcgt aagaacttaa gttatcggag
    21721 gtgaaactaa tgccaaacat tgaatctgca atcaaacgtg ttcgtacaag cgaaaacgct
    21781 aatgtgaaaa attcatctca aacaagcgct atgcgtactg caatcaaaaa atttgaagat
    21841 gctgtagctt caggtgctga caacgtagat gcgttatata aagaagctgt taaagctatt
    21901 gatatggctg aatcaaaagg tctaatccac aaaaacaaag ctaaccgcga caaatctcgt
    21961 ttaagcaaaa aaatcgctaa ataaaagaat cggcttcggc cgattttttt atttgtcaaa
    22021 aaaaggacaa aaacaaacga ccttcccgca tgctttgccc tcgtctttct tcttatcgat
    22081 ttcttaacaa ctgccctgtg cgcaaaacga atagttgaaa acttaattct ttttcgattt
    22141 gtcccgtttt gatttgataa tccatctcaa ctaattgatc aaacaactgt accagcaaat
    22201 gttcatcgaa tttttttact tcctgcatgg caagttttac acgatatgga tggattttca
    22261 atgtttcagc aatatttgcc tgctgataac caatctttac aagaaatttt gtctgtaaaa
    22321 ataaacgtaa ttgagaaagc aaaatcgcat taattttgat tgtttcttcc ccttgcataa
    22381 ctaaatcttc gtataaacgc aaagcttgtt ccgtcttccc ttttaaaata tattgggtca
    22441 tgtcaaaaat attatgttct aacgttttag gaactaattc ttctacttct cttaccgtga
    22501 tttgctgttg attttgtcca taaaggacca atttctgtaa ctctctcatc attttggata
    22561 aatctaagtc ggtcaacctc aagaataaat caattgcact tcgttccatt ttgattgagg
    22621 aattctctaa ggtattcatc agatattgac gtacttcttt ttcattcaac tgttggacat
    22681 tgatgataat tgctgttttt ttcaattgtt tcgttacttt tttccgttca tccaactttt
    22741 catatggcgc aaagaatact aatacagtcg attctaatgg ttctttcaaa taagccgtca
    22801 ataaatcagt attttgttcg attccattgt ttactttttc acctgttaaa aaataaggat
    22861 tctctacgaa tactaaccgt tgatctccga aaaacggcaa cgtctctgct tcagctacta
    22921 cctcatctaa acttgcattt tccatgtcaa aacttaaaaa atttaagtca tcttcgccct
    22981 ctaattggat ttttttgaca atttctgtcc gaacttgatc ttggagaaac ttttctgttc
    23041 ctaaaatcaa gtaacaagat gcaagttttt ctttacgtat tttttgtaac tctgcttgta
    23101 tactcaaatt actcaccact ttcaaaaatt atcctaccat gagcagatga gaattactag
    23161 tctatcattg tttccactag cccatgagga tgaaaaactg gatgccagcg ataggtgatc
    23221 attccttgtt gatccgttcg ccatgttttt atctgatttt cttctagtgt ctccaatact
    23281 tcgctgtgcg ggtgaccata acgattattt acgccgcagg atataatccc atgttttgct
    23341 tcaatatggg aaagaaaatc tgtgttactt gacgtacggc taccgtgatg acctaatttg
    23401 actacatcgg ctttcagatt aggataaatc aaaagcaatt gtttttccat tgcttgattc
    23461 aaatctccta aaaataaaaa gcgcctattg ttatattcca tccatagacc aatcgaatct
    23521 tcatttcttc cctctccctt ttcaaaagga gtcaatacat aaagatcata ataaccgctg
    23581 atcctgtccc catgtttgat ttcaatgatc tcagtaccat ttttttgagc ttcagataaa
    23641 tgcctttgta atggctcatt tcgtccagcg ccccaaccga tataaatttt tttgatagta
    23701 aaatgctgag ataacgtggg taattctccc acatgatccg tatcgtcgtg tgtcaagatg
    23761 agtttatcga ttacacttat cccctgacct tttagatatg gaacgatatt tctttcagca
    23821 ggaggacgta tcataccttg cgcccacttt tctctttcaa agtgtaactg acctccagta
    23881 tcgatcaaaa tcgtttcttt tcgaaaagga ctttgcaaaa agatactgtc tccttgaccg
    23941 acatcgataa aagcgatcgt tgaagaaaag cgtaaaaatg gcaaagtcaa aaaaataaaa
    24001 gaaaaaagac caacataaaa caagtgtttc acaggttgtt ctttcaacct atccatacaa
    24061 atcagtaatc cgaaaatata catcccagat agcacaaggg gcaaacgtcc tataatgaga
    24121 gacgaccctg aagaaaaatc gattattcgc tcaaataaga ttaatccctc ttctatcagc
    24181 aaaagtaaag tttccggcag ccagcgattg aagagtgtga gaaataacac accaggaaga
    24241 aaaagaaact tgaataccgg tgcaatcagt aatgtaaaaa gactacctaa aataggccac
    24301 tcataaaaat gccatacaat caacggcatc gtgatcatag taaacaggac gtgagaggcc
    24361 gtttttttca accaatctcc atcaaaagaa atcaggataa acaaaaaact catgaaaaaa
    24421 ctaagctgtc cacccgcatg aaaaagaaat cgaggatcaa atagtaaaag aagccaaaag
    24481 acaactgcaa ataagtccat ggtggaataa tgcttattca gcaatttgac tagcaatcgc
    24541 aataaaaaca gcaaactagc acgcaaaaca gaaatagaac ttcctgcaat agaaacataa
    24601 cagatagtta gtagactcaa cggaataata ctgacgtgta gtggccatcc gatacgtcga
    24661 aataaataat acagccaccc taaataaaat tggatgtgta gacccgatag actgaacaga
    24721 tgcagcaaac cactctccct aaaaatttct tctggttctc tgaatcctgc atctttatag
    24781 ccccataata aagaattaat atatacactt gttttttgcg gaaattcaga ttggacaaag
    24841 gagataaaag atcctctttt tctctgaagc cagtttcgcc agtgattttg catggtgatc
    24901 tgttcaatct tttgaatttg gaaccgtcca gaaattctat ggttcctgaa gtaagcttct
    24961 tggtcaaaat tataaagatt ccgctttttt gctggagaga tgaactcgcc ttcagcagtc
    25021 aattctattc cctttcctcg gaagttaagc catgttttca attctgcttc tgtgtttact
    25081 tgataagaaa gctggagctt ttgtttattc tctgataacc ttccttccat tgtcaaaaaa
    25141 ttaccatttg cacgaatcgt atctgtaaat acagtaattt gcgcagatgt tgttttttcc
    25201 tctaaaaatg aatactcttg tagcctataa gaaatggata ccgttatgct acacaaaata
    25261 cacaagtacg cgataaaacg tccttctttt agcgaaaacc ataaaaaaat tccggcaaga
    25321 agcaaacgat aaccccaatt gtcagtgtaa tacaacaaac agataatcat cgacgtaatt
    25381 gccggaaaaa tcaaccgatt tcgaacatgc ctttctaaaa cgctagacat gttttcctgt
    25441 taattcattt tgaagttttg aaaaatgctg tgagtctaaa gcaacttggt gtacagatac
    25501 acctaattgt tcgatcaacg cttgggcata aggatcattt cgatagtcat ggagataatt
    25561 gatccctttc acaccagctt gcaacaaagc ctttgtacag gccaaacatg gaaaatgtgt
    25621 gacatagatt tctgaacctt ccgtcgggat accaagtttt gcacactgta ggagtgcatt
    25681 catctctgca tggatcgttc gcaagcagtg tccatccacg acgtaacacc cttcatctat
    25741 gcagtggaca tctccactga ctgctccatt atagccgcca gcaatgatcc ttttttctcg
    25801 aacgagtgtc gctcctactt ctaaacgtgt acacgtacta cgtaaagata acagtactgc
    25861 ctgagccata aagtactggt cccaaggaat gcgttcatta tgtgacttat cagtaacttt
    25921 ttctttattc gtatcgcatg cttttgaaga tttttctaac atgttttata ttcctccgtt
    25981 ttttcaagtt gattaaaaag tactcattgc ttaaacaaaa tattctttaa atataacgaa
    26041 tcatcctgtc tgacaaaaga tcctaccctt cactgccgaa atgaagtccg tcatccatta
    26101 gcccattata aaaattcttc gaatccattt gttcaagaaa ttccgtataa aaatcgatac
    26161 ttcacaatca tggcgttttg ctacttctgt gagaacagag atatattctt tgatcaactt
    26221 gttattccga tatttttgtt ttgtctcatc gactgctggt ggcgtgataa agaaagcatg
    26281 atcagaacta tagtcttttt tcagctgaac tatcatccac tgcagatttt ttggtacgtt
    26341 tctttagaaa gttgtttatg ctctgctaga tcattcgtcc caatgagaat aaatacttta
    26401 tctgctgtat agctaagtac atctttggca aagcgttctc gtagagcttg actgttattg
    26461 ccgctgacag ccgtattcat aatatgaatc ccagatattt tattttggag atagacattc
    26521 agcattggtt tttttaatgt ttctttgcga acaatcaagc tatttcctat ccaaaaatac
    26581 tacctcctcg tcctgccaag ctcttagaat tggattattc ttagtatcca ttagcgtcca
    26641 tttattgctc gtgccagtcg attttgaatc attctattta attgtaacga agttttttag
    26701 tttttcaact gtcttttcac cgataccaga aatctcctgc aggtcttcca ctttctggaa
    26761 ggatccgttt tcttctctaa atcgaatgat ttcttgcgct ttgactgatc cgatcccagg
    26821 aatctgctga agttctgatg gagtggctgt attgatattt attttgggag gctcggaatc
    26881 tgctgtaggc tgttttcctt ccgaggatgc caactgatca agatgttctg gcagctcttc
    26941 acctacagca gggatatata ggacttgctg atcttctatc ttcgcagaaa agttgattcg
    27001 atcgctatcc gcttcttcta ataatccacc tgcacgcttt agtacatcat agacccgttc
    27061 ttctgaagaa aaggaataga taccaggctc cttcacactt cctttgatat cggtgtacat
    27121 gacctttgga cgagcatcct cttctacatc gtttccttca gctgatggat cttctccact
    27181 ggaactaaac gaagaaagta tttcttttgc agcagtctct tctgtttctc tataaaatag
    27241 caaatttgat aataaaaaac cacttgcgat acaaaagata agaactatca tagacatcca
    27301 aatgatcaat ttgggtgaag ctagtatttt cttgctgatt ttttctatca ttgttctttt
    27361 ttcaaagaat gaccagtaaa aatcattcat tactcctttc atttaaaatt gaagaaacag
    27421 tgagctctgg caaaatcgtc ccttcaacat ctaattacgt caattttttc ttttgttttt
    27481 atttttatcg tgaa
//
LOCUS       DAYNVV010000036        25998 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.036, whole genome shotgun sequence.
ACCESSION   DAYNVV010000036 DAYNVV010000000
VERSION     DAYNVV010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25998
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.036"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            289..606
                     /locus_tag="ACGXWR_001710"
     CDS             289..606
                     /locus_tag="ACGXWR_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFK0803271.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNASIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(697..1062)
                     /locus_tag="ACGXWR_001711"
     CDS             complement(697..1062)
                     /locus_tag="ACGXWR_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803272.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1270..1752
                     /locus_tag="ACGXWR_001712"
     CDS             1270..1752
                     /locus_tag="ACGXWR_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803273.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     LVVSRNFPALTVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDSAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1949..2839
                     /locus_tag="ACGXWR_001713"
     CDS             1949..2839
                     /locus_tag="ACGXWR_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HFK0803274.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            3165..5639
                     /locus_tag="ACGXWR_001714"
     CDS             3165..5639
                     /locus_tag="ACGXWR_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFK0803275.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGHQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKVIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLLKRRNNTVAMTGDGVNDI
                     LAMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLV
                     KNIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNV
                     MEKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKF
                     RSQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLF
                     ERKNEKEQKPFSRVVKKFLSIFKREN"
     gene            complement(5742..7478)
                     /locus_tag="ACGXWR_001715"
     CDS             complement(5742..7478)
                     /locus_tag="ACGXWR_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFK0803276.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNGDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRAYTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLHGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(7475..8179)
                     /locus_tag="ACGXWR_001716"
     CDS             complement(7475..8179)
                     /locus_tag="ACGXWR_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFK0803277.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            8310..8813
                     /locus_tag="ACGXWR_001717"
     CDS             8310..8813
                     /locus_tag="ACGXWR_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HFK0803278.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            8773..9111
                     /locus_tag="ACGXWR_001718"
     CDS             8773..9111
                     /locus_tag="ACGXWR_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HFK0803279.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            9132..10550
                     /gene="ffh"
                     /locus_tag="ACGXWR_001719"
     CDS             9132..10550
                     /gene="ffh"
                     /locus_tag="ACGXWR_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HFK0803280.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            10662..11240
                     /locus_tag="ACGXWR_001720"
     CDS             10662..11240
                     /locus_tag="ACGXWR_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HFK0803281.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            11244..11765
                     /locus_tag="ACGXWR_001721"
     CDS             11244..11765
                     /locus_tag="ACGXWR_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HFK0803282.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(11844..12398)
                     /locus_tag="ACGXWR_001722"
     CDS             complement(11844..12398)
                     /locus_tag="ACGXWR_001722"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFK0803283.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            12651..12926
                     /gene="rpsP"
                     /locus_tag="ACGXWR_001723"
     CDS             12651..12926
                     /gene="rpsP"
                     /locus_tag="ACGXWR_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HFK0803284.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            12938..13189
                     /locus_tag="ACGXWR_001724"
     CDS             12938..13189
                     /locus_tag="ACGXWR_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HFK0803285.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            13313..14104
                     /locus_tag="ACGXWR_001725"
     CDS             13313..14104
                     /locus_tag="ACGXWR_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803286.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTATTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            14274..14795
                     /gene="rimM"
                     /locus_tag="ACGXWR_001726"
     CDS             14274..14795
                     /gene="rimM"
                     /locus_tag="ACGXWR_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HFK0803287.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            14785..15546
                     /gene="trmD"
                     /locus_tag="ACGXWR_001727"
     CDS             14785..15546
                     /gene="trmD"
                     /locus_tag="ACGXWR_001727"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HFK0803288.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            15682..16029
                     /gene="rplS"
                     /locus_tag="ACGXWR_001728"
     CDS             15682..16029
                     /gene="rplS"
                     /locus_tag="ACGXWR_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HFK0803289.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            16339..16581
                     /locus_tag="ACGXWR_001729"
     CDS             16339..16581
                     /locus_tag="ACGXWR_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HFK0803290.1"
                     /translation="MNDGKVKQVPSSTKKKNILLKEVLKRFDHGVTYTETEVNSILLN
                     VFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(16669..16815)
                     /locus_tag="ACGXWR_001730"
                     /pseudo
     CDS             complement(16669..16815)
                     /locus_tag="ACGXWR_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332517.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamate
                     endopeptidase"
     gene            16872..17186
                     /locus_tag="ACGXWR_001731"
                     /pseudo
     CDS             16872..17186
                     /locus_tag="ACGXWR_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345994.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
     gene            17215..18474
                     /locus_tag="ACGXWR_001732"
     CDS             17215..18474
                     /locus_tag="ACGXWR_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFK0803291.1"
                     /translation="MKRWKKMMIGSIVLGMSLVFGACGNQEDSSEESANEITVSTWNY
                     ETTPEFKALFEAFEKKTGIKVKAVDIASDDYDTKLTTMLSSGDTTDVLTMKNLLSYSN
                     YALRDQLVDQTERIRELDTDAAEETYEMYDIDGKTYALPYRTDFWVLYYNKKMFDDAG
                     IEYPKNLTWDEYEDLAKKLSKNDGQVYGAYQHIWRSTIQAIAAAQNEANLVEPDYQYM
                     TDYYDRALRMQKEGAQMDFGTAKSTKVTYQSQFEEQKAAMMYMGTWYMAGILANKEAS
                     KTEVEWGITAIPQKKKGESVTTFGSPTAFAVNKNSKKQKAAQEFIEFAASEEGAKVLA
                     GVGVVPSYRTDEIDQLYFNLAGMPTDEISKKAFSPDEIKLEFPIDTYGPAIDKILQEE
                     YDLVLVGDETPEKGTVNMEKRVAAEKE"
     gene            18527..19423
                     /locus_tag="ACGXWR_001733"
     CDS             18527..19423
                     /locus_tag="ACGXWR_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0803292.1"
                     /translation="MENSINKKATNHLRRKRTWIAYSFIAPNFIGFFVFTLIPILFSL
                     VLAFMKWDSFSTPEFAGLDNFRKMANDETFWISLKNTFLYTAAVVPGTLVCSLGLALL
                     LNQKIRGMKLFRTIFFFPYVTSLVAIAVVWNMLFHPTVGPINIFLRRFIEHPPGWTSS
                     SNWALWAIVIVSIWRGMGYYMILYLAGLQSIQKELYEASSLDGANRWKQFLNVTLPSL
                     RPTTFFVTIMLVINCFKVFDLVQVMTDGGPGRATNVLVYQIYNEAFKKFDFGYASAIS
                     LVLFVIVLGVTVVQFSWNKRRT"
     gene            19434..20303
                     /locus_tag="ACGXWR_001734"
     CDS             19434..20303
                     /locus_tag="ACGXWR_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0803293.1"
                     /translation="MEESVRNERKKAKIRSKNMPFIQWLGMILLIVLALLTIIPFLWM
                     VSASFKANNEVLTIPIQWIPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFT
                     SSFAVYGFSELNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVGLTDTLWSLVLLQ
                     AFNAFGVFLLKQYYSSIPDSLCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVN
                     TWNDYMGPFIYLSSTENKTIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQK
                     YFVEGIASSGMKE"
     gene            20313..20988
                     /locus_tag="ACGXWR_001735"
                     /pseudo
     CDS             20313..20988
                     /locus_tag="ACGXWR_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
     gene            21194..22858
                     /gene="alsS"
                     /locus_tag="ACGXWR_001736"
     CDS             21194..22858
                     /gene="alsS"
                     /locus_tag="ACGXWR_001736"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0034077 - butanediol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HFK0803294.1"
                     /translation="MAEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVEKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAKLTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            22871..23581
                     /gene="budA"
                     /locus_tag="ACGXWR_001737"
     CDS             22871..23581
                     /gene="budA"
                     /locus_tag="ACGXWR_001737"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HFK0803295.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            23711..24208
                     /locus_tag="ACGXWR_001738"
     CDS             23711..24208
                     /locus_tag="ACGXWR_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HFK0803296.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            24393..24653
                     /locus_tag="ACGXWR_001739"
     CDS             24393..24653
                     /locus_tag="ACGXWR_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803297.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVIGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(25015..25254)
                     /locus_tag="ACGXWR_001740"
     CDS             complement(25015..25254)
                     /locus_tag="ACGXWR_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803298.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            25540..25854
                     /locus_tag="ACGXWR_001741"
     CDS             25540..25854
                     /locus_tag="ACGXWR_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803299.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT         8635 a         4373 c         5306 g         7684 t
ORIGIN      
        1 agattacaaa tagtatcgta tttcgcaatc ttaaaattat cttcttactg tgaataagat
       61 aataaaattt gtatttgtcc tttttaggta acttatttta atctatatac ctttctggat
      121 caacgaaagt atactttata tagtcataac gccgatggta actatgcact gtaacgataa
      181 tgctgctaaa atatcttttt acgaaaaaca tcacaaggaa aaacttaact atggtattat
      241 ctaaacataa ttttttcggt atttaatatt taattaggag gtaatatttt gcttttttat
      301 agtaatttta tcttaatagt agcgatatta ttacttctga atatatggat ttttgatagg
      361 agtagaaatg caagtatagg ttttagaact aaacgaagtc tgtcttctaa aaaaaattgg
      421 gtatactcac aaactatttt ttatggagga attgttttaa ttagtttact ttcttcaaca
      481 ctttattctt tgaatattat agatgtttcc acctcaaatt caatatctat tattggaatc
      541 attattgctg caattattac acaactgttt ttagtgtttg gagagaagaa aagaagtaaa
      601 aaatagaaaa actagtgata gttttggtga tataagaaaa acatatatgt ataaaaagaa
      661 gaaagtagct tctctttgta catatatggt ttgtttttat ggatgccgag cttttttata
      721 agataaggct accgcccata acgacccaag gatttgtgga actaagtaaa tacctgcaag
      781 aagcaagatc agctgggtcg gttttaaagg atgatagaag taacgccatt cagtaaaatt
      841 ggcgcaaaat aaataggaag tgacagtaga tataatattg gcaatgaata aagatataat
      901 acgcctgttc ctttgaaaat aatatccagc aaaaagagat aaaaatatca atgtgatgaa
      961 cccgcttacg gaatgataac gaaaatcaag cagtaaggcg aaatgcacat aaggaacaaa
     1021 agataaaagc aacggaaggt ttttccagca agtttttatc atctttcatc accacctaac
     1081 aagtgttatt attttgttag ttttattgta aattgaatcc tgcaataatc aattactttt
     1141 tcattatttc tagattaaat gaataaactc tcatgccatt atctctaaaa aaaaagtttt
     1201 tccccctaat ttttttagat agaaaattgt atagtatgat gagagaaaaa gtagtttggg
     1261 ggaacgttaa tgagaagaaa agcagtaatc gatcggcttt atttattttt ttggtttttt
     1321 cctatcgttt tgctaccttt tacatgggta aatgctgttg tacaaggtgc ggagatatta
     1381 ggcctgatcc aaggaagcgg attagtggtt tctaggaatt ttccagcttt gactgttttc
     1441 tatttagtga taagtgtagg tctcttatta ccaaaatctc tgatcaatca ctacaattgg
     1501 cagctgcttt acttttcttg cttattagta tttacatcta tgttttcttt gctgcctcgc
     1561 ttgattatcg gccctaatgg tttgagcgag agtggattga aggattcagc ttattcctcc
     1621 atgtatttct tgacgatcaa accatggttc tatttagtaa ttgcctcatt tattcttgca
     1681 acattttttt acttctggac agaaatcagg ataaaaagtg aacgatctgt atctataaaa
     1741 aataactatt gatggtggat catcagtaaa aaagcatatg agctgcgtaa aatgcatgtt
     1801 tctcatatgc tttttttatt attatgtaaa gaatgcgaaa aacgtttaca tgatttttac
     1861 ataacttaac tatattttta cagcaaccat acgagggatt tacagtcgac tgataaactt
     1921 tagttgtaaa taagaaagga gcaataaaat gaaaaaagta ttgtttactc taggtatgat
     1981 gggaattctt ttagccggat gcggctcagg atcaggaaat acagatggct ctgccacaca
     2041 aaataattca agtgactcaa atgaacaagt aaaaatcgtt gcggtaggtt cgacagcatt
     2101 acagccgtta gtcgatgcag cacaagaaag ctttgtacaa gaaaatccaa attatcaaat
     2161 ctctgtacaa ggaggaggaa gcggaactgg tttgagccaa gtcgaagctg gagcagttac
     2221 tatcggaaac tctgatgtat ttgcagaaga aagagacgga gttgatgctt caaaattagt
     2281 ggatcataaa gtagcagtgg tcgggatggc accaatcgtc aataaagata cagatgtcaa
     2341 agatatcacc aaacaggaat tgattgatat ctttacagga aaaatcacta actggaagga
     2401 agttggcggg aaagatcaaa aaatcaacgt cgtgaaccgt gcaaacggca gcggtacccg
     2461 cgcgacattc gaaaaatggg gactggatgg tgctacccct gtgcagtccc aagaacaaga
     2521 ttcatcagga acagttcggc agctggtaag tcaaacacca ggagcaatca gctatttagc
     2581 tttctcatat ctcgatgatt ccacacaagc actaagtatc gacggtgtag aaccaaaaga
     2641 agagaatgta gcagataaca gctggggaat ctggtcatat gaacatatgt acacgaacgg
     2701 aaaaccttcc cctgaagtcc aaaaattctt agactacatg atgacagaag aaatccaaga
     2761 aggacctgtc aaagaattgg gctatttacc aatcacaatg atggaagtag aacgtgatca
     2821 cgaaggaaat atcaaataac tagcagataa acatgccacg gtagtcgtta ctattaagga
     2881 aaaatcaact atgtttcccc acatatacat ttttccttta attgtgaaaa atagttcctc
     2941 atattttgcc gttttttgag ctaataccga gggtcagctg attgaacacc gtttattcga
     3001 aaaaaagagc tacgacatag aactgtcgta gctttttttt tgctatatga caggaatgaa
     3061 aggtgtttgc aagcttaatg tgaggaacac tttccatatc tgttctatac tggataggag
     3121 aagtttggaa atatccagaa aacgaaatca atcgaggtag ccacatgaag aataaatgga
     3181 taaatcgaag taaaaaaaag aaagtaacac aaagatcatc agataaagtc atccgtcttt
     3241 ttccatcgta taaagaagga ttaacggcag atcaagtcaa ggaacgaata gaaaaaggtg
     3301 cagcaaataa ttcagtcgat cccacattca aaacaaatca gcaaatcgta ttggaaaaca
     3361 tatttacgta tttcaatttg atctttctta tcttagccat tttgctttgt ttagtagaat
     3421 cctataagaa cttgactttt ttaccagtta tcatagccaa tacaggaatc gccatttttc
     3481 aggaaattcg atccaaaaag atcttggacg aactaaatgt tttaaataca gcaaaagtca
     3541 atgtcatacg agacgggata gaacaaacaa tagatataga agaccttgta atagatgaca
     3601 ttgttatttt agagactgga catcaaattc cagcagatgc agaggtcgtg gaagggaaac
     3661 tgcaagttaa tgaggcttta ttgacaggcg aagcagatga aataaccaaa gaaataggcg
     3721 atccattaat gtccggcagt ttcattgttt ccggaaaagc ttacgcccga ttagacaaag
     3781 ttggagcaga ttcgtatatt tcccagctga cagtcaaagc caagacaatg ggagaaggag
     3841 aacagtcgga gatgattgct tctcttaatc aattgatcaa atggattggg atcatcatta
     3901 ttcctatcgg tatcctgctt ttttctcaaa gttacttttt taatggaaac acgatcaaag
     3961 aaagtgtcgt tgcaatggaa gcagcattga tcggtatgat acctgaagga ctgtacttgc
     4021 tgacgacgat tgcattagca ttaagtgcga ctaaactagc aaagcaaaga gttcttttac
     4081 acaatatgaa aagcattgag acattggcaa gggtaaatgt cctttgtgta gataaaacag
     4141 gaacgatcac agaaaataaa atgtctgttc aaaaagtgat cgtctctaaa aaacaagaaa
     4201 taatcagtca gtcagatcaa ttggaagcat gcattgctga ctatgcaaaa gcgatggcag
     4261 gagacaatgc aacaatggaa gctgttaaag catattttac aaaaaccact gatcaatcct
     4321 atcaccatgt tattcctttt tcttctgtcc aaaaattcag cagtgtagcg ttggcagaca
     4381 aggtgtatgt tttaggagcg cccgaaatgg ttttgcgcga tcaattgccg gaatatgcgg
     4441 aagagtttgt ttctttcgct gaaaaaggct atcgcgtgtt ggtctttggt gtgtacgatg
     4501 ggattcttga agaaccagta ttgacagaag cagtcacacc attaggctat attctgattg
     4561 ctaatcctat cagaaaagaa gcaagagcca catttgatta cttcaaaaaa cagcaagtag
     4621 ccatcaaagt gatttctgga gataatccgc tcaccgtatc caatgtagct gtccaagcag
     4681 ggatttcaca tgctgatcag tacgttgatg catctaaatt atcagaagaa gaatatgaag
     4741 cagctgtcga aaaatataca gtttttggac gcgtcaagcc agaacaaaag aaaatcttcg
     4801 ttcaattgct aaagcgtcgt aacaatacag tagctatgac aggtgatggc gtgaatgata
     4861 ttctagccat gaaagaagca gactgcagta tagcgatggc ttccggaaat gaagccgcca
     4921 tgcaggcctc acaagtggtc ttacttgatt ctgacttttc acgcatgcca gaagttgttg
     4981 cagaaggacg gcgcgttgtg aacaatattg agcgatcagc cagcttgttt ttagtgaaga
     5041 atattttctc ctttttgctc tcactgtttt cagtgatctt tgctctgacc tatcctttag
     5101 aaccatcaca aatcacattg attagtttgt ttactatcgg acttccatct ttcttgcttg
     5161 ctctagaaga aaacaaaaag cgaatcagag ggaaattcat catgaatgtg atggaaaaag
     5221 ctgtgccagg tggactaaca gatatgatcg tagtcggtgc gttggtgatc tgcggggtga
     5281 ctttgaatct aaataaaaca gatgtttcta cagcatctac catgcttttg attgcagtag
     5341 ggttcctcgt tctctataaa atctgttcac cgctgaataa attcagaagt cagatcattc
     5401 ttttctgtgc tagcggtaac tttttttcgg tcatcttttt gcataagctg ttttcaatca
     5461 ccggtatctc agctgtatca cttttgctgt tgagcattct atttttctcg gcagattcga
     5521 tttttaggca tttgaccaca ttggtagaat atttgtttga acgtaaaaat gaaaaagagc
     5581 aaaagccgtt tagtcgcgta gttaaaaaat ttctatcgat atttaaacga gaaaattgac
     5641 gaaaagtatc tcaaaaaaga gtaaaaaaga acaaccactc gtgtatcttt cgaagcagga
     5701 tgagtcatcc aactttaaaa cgcacgagca gttgctcttt tttacatttt cggaatggta
     5761 acggtgaaag tcgaacctgt tccaagatga ctgtctacag taatcgtacc atgaaggagt
     5821 tgcacgtagt cttttacaat cgctaaccct aatccggtcc cgcctgaatg ccggcttcgc
     5881 gccttgtcta cgcggtaaaa acgctcaaag atccgttcct gatcctcaat gtcgatacct
     5941 ataccaaagt cttggacaga aaacgataga tcatctgttg cctgatagcg gataataatc
     6001 tcgctgtcgc tttttgaata ttggacagca ttttcaatca gatttttgat aattggataa
     6061 aggatatctg ttttagtagt aaatggttcg ttctttccaa tcaatcgaat cgtcaaccgt
     6121 ttcttttcga tgattggctg ataattttga acgatttgct ggaaataagg ttctgtataa
     6181 attgtctgga tctcgtaaga attctcgcca tcttttgaca gctggatgat ttcccgaatc
     6241 agtttatcta accggatcgc atctttttgc atgatctcaa gaaaagaagt cagagtttgc
     6301 gggtcatctt ttgcaccatc cagtaaagtc tcggtaaaac caatcagtga agtcacagga
     6361 gtttttaatt cgtgagagac gttgccaacg aaatcctttt gtagcttttc taaacgtcgc
     6421 actttcgtta agtcatacgc cacccctaga atctgtccgg taccttctga attagtaaag
     6481 tagcgcaaac tcaagtctaa tgtctgccga ccttctgtaa gggtgatctc ctgatggatc
     6541 agcggatgct caggagtcac ttgatgaatc agctgaatga gttttggctc ttgaatgact
     6601 tctgtgtacc gctgttcagg ttgatagctt accacgttta aatgtagctg catctttgga
     6661 ttaagcagta gtaaacgaga atcagcatca tcaatcagga atacgccaat catcagttcg
     6721 ttcagtaacg tatataattg ctcttctgtg gtagtatacg cccgatacat cttactcatt
     6781 tgttcgctca acgcattgat cgtctgatac aattcttccc attgatcggg tgtttgcatg
     6841 attacttccg cctgattagg attttgcacc atttttttta gtacgggcag cacggttttc
     6901 aatggctggt ttttttgata gatcagataa tagatcattc ctgcaagaac aaggaagaaa
     6961 gacagaaaga agaaaaagac ccaacggcga aaactctcag ttctcggtaa aaaaccgctt
     7021 gtcggttctg cgatacgtaa aatggcttct aactggccac tttttttgac tggtaatgcg
     7081 acatataaaa gatccccatt caaagtagta cttttgcgca aagcgctacc taggttccca
     7141 ccattcaata cggctttgat ttcgggacgg gagtttcgct gttcattcaa tgtttcattg
     7201 tttgtgtcaa ataagatctt tccagtagca tccattaaag taatccgttc gttcgactga
     7261 tggacgaatt cttccaaagc agttttgttt tgcgctgctt ggaggttttc gacatctaat
     7321 tgccggatca gcagttgtgc tttttttgtc aggtagcttt cttgctgttc cacgatctgc
     7381 tgttgaaaat aatgggaaat caattgccag ccaccaaaaa acaaactaac taaaagaata
     7441 agaaagaaga gacgttcata aatttttttc catttcatcg tttgggttcc tgaaacttat
     7501 agccaaatcc tctaatagtc accaagtact ttgggtgttt tggatctcgc tcgatttttt
     7561 ctcgcaaatg actaacgtgt acatctacga ttcggctttg tcctgcgaag tcaaaattcc
     7621 aaatgcggtc tagcaatgtg tctcggtcga tcacacggtc ttttcgtttc atgaaataaa
     7681 caagtaattc aaattctttc ggtgttagtt caatcagatg gtcgtctacg gtcacttgat
     7741 aattggtcaa atcagcagtg atttgtccaa tcgatagata ttcaggctca gcttcatctt
     7801 ttgattgctt acgaggttca attcgtctga atattgcttt catacgggct aatacttcgc
     7861 gaggactaaa tggtttggtc aaatagtcgt cagcacctat ttctaggcca atgatccgat
     7921 ccacttggtc atctttagcc gtcagcatca aaatcggtgt ttcatttttt tcttgacgca
     7981 gccgctgagt gatctccatg ccatccatcg ttggaagcat cacatctaaa atgatgaaat
     8041 caaatgattg ttctaatgct aattctaatc cttcgcctcc atctgtggca ctggttacct
     8101 tgtagccttc tttttccaaa ttgaacgtca agagcgttac aatagaaggt tcatcatcaa
     8161 caactagtat ttttttcatt caaatctcct ttaaataggt ttcattctgt ttatatttta
     8221 gcatagaatc agtacaaagg gctattttac aaaagaaata aatggtataa taggaaggca
     8281 ctttgctgaa tagaaaggaa gagcagtcaa tgattggaat cagtgcatgt ttaggcggtc
     8341 tggcctgtcg ctatgatgga cagaaaaaag aagtaccaga attgatggaa ctagttgaaa
     8401 ctggagaagc tgtcatggtc tgtccagaag tgatcggcgg attaccaatt cctagagatc
     8461 ccgctgaaat cattggtgga aatggattcg atgtgtggaa agatcaagca aaagtatgga
     8521 cgacaagcgg cgaagatgta acggaagcgt acaaaaatgg cgcgatcaaa gcctatcaaa
     8581 aattgcagga aaaacacatt gatctagtca tcatgaagga aaaaagccct tcatgcggaa
     8641 cccattcgat ttatgacggg agtttttccg gaataaaaaa aaatggtgcc ggagtggcta
     8701 ctgcttattt tattcagcaa aaaatgactg tgctctctga tgaagaatgg ctgaaaacta
     8761 gaggtgagca gaatggaaat cgaaaagacc aatcgaatga acgcgctctt tgaattttat
     8821 tcgaccttat tgacagaaaa acaaatgaac tacatggaat tatattatgc agatgatttt
     8881 tcattaggtg agatcgcgga agaatacgaa gtaagccgac aagcagtata tgacaatatc
     8941 aagcggacaa gcaagatctt ggaggattat gaaaaaaaac ttcatctttt ttctaattat
     9001 attgttcgag aacaggtatt ggaaaatatg actgcatata ttacagataa gtacccggaa
     9061 gataaaaaac tacttgaata tgtacagcaa attcaagcaa tcgaagaata aataaaagga
     9121 atgaagaaaa tatggcattt gaaagcttaa ctgaacgtct ccagcaggcg atgggaaaaa
     9181 taagaaaaaa aggaaaagta tcagaagctg acgtaaaaga aatgatgcgg gaaatccgcc
     9241 ttgccttact agaagccgat gttaacttgc aagtagtcaa agattttact aagcgcgtac
     9301 gcgaacgtgc ggtaggggca gaagtgctgg aaagtttatc acctgcacaa caaatcgtaa
     9361 aaatcgttga tgaagaattg acgatcacac ttggttctga aacagcagag ttaaataaat
     9421 caccaaaaat accaactgtt atcatgatgg ctggtcttca aggggcaggt aaaacgacct
     9481 ttactggtaa attagccaat tatttaaaga aaaatgaaaa tgctcgtccg ctcctaatcg
     9541 caggggacgt atatcgacca gctgcgatcg accaattgaa agtattaggt caacagctag
     9601 acgttcctgt atttgatatg ggaactgaag tcagcccggt agagatcgtc cgtcaaggga
     9661 tggagttagc aaaagaaaag aaaaacgact atgtattgat cgatacggca ggacgtctgc
     9721 atatcgatga aacattgatg gatgagttga aacaaatcaa agaattgacg caaccaaatg
     9781 agattttgct tgttgtcgat gccatgactg gtcaagatgc cgtcaacgta gctgatagct
     9841 tcaaccagca attaggtatt acaggggtcg tcatcactaa acttgatggg gatactcgag
     9901 gcggggcagc actatcgatc cgctcagtga caggcgcacc aatcaaattc atcggttctg
     9961 gtgaaaaatt gactgactta gaagtattcc acccagatcg tatggctagc cgtatccttg
    10021 gtatggggga tatgctgaca ttgattgaaa aagcgcagca agactatgac gagaaaaaag
    10081 cggaagaact tgcacagaaa atgcgggaaa attcattcga tttcaatgac tttattgaac
    10141 agcttgatca agtgatgggt atgggcccac tggaagatct aatcaaaatg atcccaggaa
    10201 tgaatcaagt ccctggaatc gaaaacgtca aggtagatcc aaaagatgtt gaacgcaaaa
    10261 aagcgatggt ttattctatg acgccagcag aaagagcaaa tcctgatctg ttgaacccaa
    10321 gccgtcgtcg ccgaattgct gccggttctg gaaacagtgt tgttgaagtg aatcgaatga
    10381 tcaaacaatt caaggaatca agaaaaatga tgcagcaaat gtccaaaggg gatatgaaca
    10441 tcccaggtat ggaccaaatg tttggttcag gcgtcaaagg aaaactaggc aaaatggcga
    10501 tgaatcgaat gatcaagaaa aataagaaga aaaagaaaaa acggaaataa gatgaaaaaa
    10561 acagcttcgg tacagactga aaatgtctac tgccggagct tttctatcag caatttttat
    10621 tctttactaa tacaattact ctaaacgaag aggtggcaca gatgagatgt ccgtggagtg
    10681 aacaaacaga aagtatgcgg caatatcatg atactgtctg gggtgttcct gaatatgatg
    10741 accaaaagct gttccgaaaa ttgatgcttg atattaatca agccggattg agctggcaga
    10801 cgattttaaa taaaagtgaa gcattcgatg aagcatatga tcgattcgat attaaaaaag
    10861 tcgcaaatta tggagaaaca aaaatcagtg aactaatgga aaacaaagga attattcgta
    10921 accgaagaaa aatcgaagca gccgtccaaa acgccaaagc agtcttgaaa attcaagaag
    10981 aaatcggcag tttttcagag tatctttggt cgttttctaa tggaaaaatc gttgattctt
    11041 cttatcattc acaagaagaa gtcccaacaa caagtcctct ttcagatgaa ttagcaaaag
    11101 atctaaagaa aagaggattt aaatttatcg gaagcacaac aatctatgct tttttagaag
    11161 ctgtcgggat catcaatgat caccttgaca gttgtttccg caaagaagag gtcgtacgta
    11221 tcggcagaaa gggcgaataa agcatgcgaa aaatcatatt ttatggtgct ataagtttag
    11281 atggctattt ggcaacgaaa acggatgatc ttcaatggct ttttgacact ccaacaggta
    11341 agcaaaccac ttatgaagct ttttatgaaa caatcgatac gaccatcatg ggcagaaaaa
    11401 cttatcagga agcaaaaaaa tatttggaga ccgaagcaat ttatccagag aaaaagaatt
    11461 tcgttttttc cacccacgca caattacaat tgccagatgc tgaggtcgta aacgaagatc
    11521 ctgttgcttt tctaaaaaat ctacaaatga cagaaggaaa agatatctgg gttgtgggtg
    11581 gcggtcgatt gatcaaaccg ctattggaac atcaaatgat tgatgaatgg tatatccaga
    11641 ttacccctgt attattaggg gacgggattc ctttattcca aaaaggaaca tatgaagcgc
    11701 gttttgaaat gctagacacg acacgattcg gtgaatttat cgaattgcat tatgtacgaa
    11761 agtagaagta aataaaataa aaaaggcaac tatatgcaga aatgtcctgt acatagttgc
    11821 cttttttatt accgttatgc tttttactct gttaatttgt tagaaaaatc tagatacgca
    11881 tctaaaatcg tttggaagaa acttaatgtt ccttcaacga tattaccatt ttcatcaatt
    11941 agattcgcaa cgtttccgat atatgcttcc ggttgctgca aggttggcac attcaaaaag
    12001 acaagtgatt gtcgtagatg gtggtttgcg ccaaagccgc cgatcccacc tggtgatgca
    12061 gtaacgacta aacctggttt atgatcccaa acactgtgtc cataaggtct tgagcctaca
    12121 tctaaagcat ttttcaatac tgctggcaca gaacggttgt attcaggagt aacgaaaacg
    12181 acaccgtcta gtcccctcac ttcctcacga aaacgagtcc attcagcagg agcctgttct
    12241 ggagtttcga gatcctcatt gtaaaatggc agatcatcga tttttacaaa tacactttcg
    12301 tacccttcag gaagcaattt cgcaaaagct tctgctactt ttttgttgta agaatctttt
    12361 cttaaactac caataaaaaa tccaattttt tttgtcatac gatttttcct ccttcaaact
    12421 atctataaca atcttacaaa aaataagtaa ctggagcaaa taaaaacact tactgacaaa
    12481 agctacatag aagatagatt acttattttt aacaaaaaag aagtctaaaa tcttctattt
    12541 cctaaaaaaa atcgaattta atcaagctgt aaagaaaaaa agctttacag ggtaaaaaaa
    12601 aactgttaca ctacatcttg tgaataaaac aatggaggtg gaaataaata atggcagtta
    12661 aaatccgttt aaaacgtatg ggttctaaaa agagtccgtt ttaccgtatc gtcgtagctg
    12721 attcacgttc tcctcgtgat ggacgtttca tcgaaactgt aggtacttac aatcctttga
    12781 aagaccctgc agaagtagtt ttaaaagaag acttagttct tgactggtta tcaaaaggtg
    12841 cacaaccttc tgacactgta cgtaacatcc tttcaaaaga aggcgttatg caaaaacacc
    12901 acgaagctaa attctcaaag aaataaggtg accggatatg aaagatttaa gcgacttagt
    12961 cttaacaatc gttcgtccgc tagtcactta tcctgatcaa gtcaagttag acgtcgtaga
    13021 gtcgaaagac ttttacgagt acaatctaac agtggctcct gaagatattg gccgtatcat
    13081 tggaaaacaa gggcgtgttg ctaaagcaat ccgcacaatc gtttacggtg ttcggatcaa
    13141 tgcaccgaaa aaagtgcgtt tgaatatcat cgatgataag gaaaagtaaa taaacgtgct
    13201 gtactcgaat tttcgagtgc agcttttttg tttttttatt aattgaagaa atgattattt
    13261 ggcaaaacaa gcaagaaagc gtatccttat aggaggaggg agtgaacagc caatgagaaa
    13321 gaaaatgtta tttattccat ttgctctatt gttaagcgct tgtagttcgg ttactcaaga
    13381 atcagacaat acacatctat caagcagtat atctgaaact gttaccagtc cagaaaaaag
    13441 tagtaccaaa acggctacca ccactgaaca aacaatggct acctcaaata atgagaaaaa
    13501 gactgcttta gaccagttga aagaacaaca gccaaatgtt cccatgcctc tagatgtacc
    13561 agtctcttca ggctatctca atatcgcagc gacacataca aagcaaggtt attctatttt
    13621 atattacaga acagatcgtc ccctcgggtt gaatgctgac gaattgaatc aagaaacgcc
    13681 tattgcaacc tatctatatc aatatgggtt tgcttctagt caagaaacaa tccaagtttt
    13741 gcagcccttt gagatcgaca caaatggtca gcaagtggac ttaggttctc gaatcacagg
    13801 gtatcagcaa ggtgcagcag gttcaagttt tcttgaatgg caagaaggaa actggcgtat
    13861 tcgaatccgt gggaataata tagaaggcca agatccctta ctattagcta aagaaatcgt
    13921 agcttatttg gaagaaaaca gtctaccagc acctgaacaa tttggtaaaa ttactgttga
    13981 tatgggtgat acgacgaatc gagccgtaga agtaagctgg caagaaccga aaaatgccta
    14041 tacgatcact catcaagatc ctatgtctgc gttgaagatg gcagtttcta tgaagaggtt
    14101 gtgaaatcag cgcgctgatc tgagcccatc atttaactcc aagtcacagg aagtaatcaa
    14161 aaatagcacg ccgcattttt gcataatttt ggcttaatac cttaaaagaa aactagaatt
    14221 gcctcttcac acatgctaaa ataaaacaga caaaaaagaa atggggatat aagttgactg
    14281 aatacttgaa tgtaggaaaa atcgtaaaca cacaaggtat caaaggcgaa gtccgtgtta
    14341 tctcaacaac ggatttccca gaagaacgtt acaaaaaagg aacggtgtta acactattcc
    14401 aagacggaaa agcacctgtg gaattaacag tcaaaagtca tcgcaaacat aaaaattttg
    14461 acttattgag ttttgaagga catccttcta tcaatgatgt ggaaaaatat cgggatggca
    14521 tattaaaagt gtcaaaagac aactctgtag atctagctga aaatgaattc tattaccatg
    14581 agatcatcgg tctgcatgta ttagaagatg gaactgagtt aggtaaagta aaagaaatct
    14641 tgtcaccagg tgccaatgat gtttgggtcg ttcaacgtcc gaaaaaagct gatatattgc
    14701 ttccatatat cgcttctgtc gtcaaagaag tcgatttaga agctggagtg gtccgtgtag
    14761 aaattccaga aggactgatt gacgatgaag attgatgtat tgactttatt tccaagaatg
    14821 tttgaaggtc ctatggggga atccatcatc ggtaaggctg tagataaagg attattagat
    14881 atcaatatct ctaacttccg cgattattca gataacaaac atcagacagt agatgattat
    14941 ccatacggcg gtggagcagg tatgctgctc aaagtccagc ccatctatga taacatccaa
    15001 gccattgaaa aagctgcacc ggatgtcaaa aaaagagtaa ttcttcttga cccagctggt
    15061 aaacgattcg atcagaaaat ggcagaagaa ttttcacaag aagaacactt agtattcatt
    15121 tgtggtcatt atgagggata tgatgaacgt atccgcacat tagtgacaga tgaagtttcc
    15181 ttaggagatt atgtccttac tgggggagaa ttaggtgcga tggtcatgat cgatgcaaca
    15241 gttcggcttt tgccagatgt gttagggaat cagacttcag ctcaaacgga ttcttattca
    15301 accggtttat tggaacatcc ccaatatact cgcccggcag aatataaagg gatgaaagta
    15361 ccagaagtat tgacaaatgg aaatcataaa ttgattgaag aatggcaatt aaaagaatca
    15421 ctaagaagga cctatcaacg tcggcctgat cttttggaaa cacttgaatg gacacctcaa
    15481 atgacgaaat ttttagaaga aatcaagaaa gaagaacaag aaaaaacagc agatgaagcc
    15541 aagtgacttt ttctaaaata ttctttacag taggttgata atatgttagt attttatggt
    15601 gagtgcaaaa gcacttaact attacgatat tccgctatga gaaaagctca taagaatatt
    15661 tggaataagg agaagaaaac catgaatcca ttaatcgaag aattaacaaa agaacaatta
    15721 cgttctgaca tcccagcgtt ccgccctggt gacactgtgc gtgttcacgc aaaagttgtt
    15781 gaaggtactc gtgaacgtat ccagttattt gaaggtgttg ttatcaaacg ccgcggtgct
    15841 ggaatcagcg aaacttatac agtacgtaaa gtttctaacg gagtgggcgt tgaacgtaca
    15901 ttcccattgc atacaccacg tgttgcaaaa atcgaagtag ttcgctacgg taaagtacgt
    15961 cgtgcaaaat tgtactacct acgtgcatta cacggaaaag ctgctcgtat caaagaaatc
    16021 cgtcgttaat cattgttatc agactgagaa agaacccttg gtattcaagg gttctttttt
    16081 cttagcatgt aatttgaaca ccctgatcca gtttttttct ttaattattg gtaggggaga
    16141 ataatggatt agaataaatc tacctataag tagtagtaaa aaaaagagca ctatgataat
    16201 atctttctta agagtaaccg ctttaataaa aaatccagaa tattctaaca taaatggagt
    16261 attcttagaa tcaaaaggag aaagaagatg gtttatactt atacggagca agaaaaaatg
    16321 aaagtttgag acacattcat gaatgatgga aaagtaaaac aagtaccaag ttcaacaaaa
    16381 aagaaaaaca tcctattgaa agaagtcttg aaacgctttg accatggagt gacttataca
    16441 gaaacagagg ttaattcgat actgctgaac gtattttcta gtggcgatta tgtcgaacaa
    16501 agacgttatc taatcacatt tggctttttc aaaagaagtt cagacggtcg ggcatatcag
    16561 atgatgggaa ttgaaaatta gaagttttaa tttatactca ttgaaaaaag ttcaagtatg
    16621 cgatattggt tctacaccgc atacttgaac tttttttgtc atctgtatct ataatacaaa
    16681 gccaagaacg ttattcaaaa tatggatagc tatgataaaa gctaatgagc gattcgcagt
    16741 taaataagca atcgtcagta aaatcgttcc aggagcgtac atgaaaaaat caattggatg
    16801 cgttacatga ataaagataa ttctctttta tttgtacgaa taaataccaa aacgtacctc
    16861 ctaaaattag attcaaagaa gatagcaaag aggaaaaaga tagttctgca gcagctatag
    16921 cggcatgtgg attgctagaa ctttccaaac aactgcctgt ttcagatcct cgtcatttcg
    16981 attacgaaga gatagcaatc aaaatcttgg aagaattaca gaaaaactat acaacgaaac
    17041 gagttaacgg atcaaacggt ctgcttctcc atgccgttta tgataaaaac agcttaaaag
    17101 gtgtagatga atgtgtgatc tggggcgatt acttttatgt agaaggaatc actcgtctag
    17161 ctaaaacatg gtactgttac tggtgatgta taagagaaga ggaggattca tataatgaag
    17221 cgatggaaaa aaatgatgat tggatcaata gttttaggaa tgtcactcgt atttggtgct
    17281 tgtggtaatc aagaagacag tagtgaagaa tcagcaaatg aaattaccgt ttcgacatgg
    17341 aattatgaaa caacacctga attcaaagcg ctctttgaag cattcgaaaa gaaaacggga
    17401 atcaaagtga aagcagtaga tattgcttca gatgattatg atacgaaact caccacgatg
    17461 ctttcttctg gagacacgac agatgtattg acgatgaaaa atcttttgtc gtattcaaat
    17521 tatgctttac gagatcagtt agtcgatcaa acagaacgaa ttagagaatt agacactgat
    17581 gctgctgaag aaacatatga aatgtatgat atcgatggaa aaacatatgc attgccatat
    17641 cgaacggact tttgggtact atattacaat aagaaaatgt ttgatgatgc aggaatcgaa
    17701 tatccaaaaa atctaacttg ggacgaatat gaagatttag caaaaaaact tagtaaaaat
    17761 gacggacaag tttacggagc atatcaacat atctggcgtt cgacaatcca agctattgca
    17821 gctgctcaaa acgaggcgaa tcttgttgaa ccagattatc aatatatgac tgattattat
    17881 gatcgagcat tgaggatgca aaaagaaggc gcgcagatgg attttggcac ggctaaatca
    17941 acgaaagtaa cctatcagtc tcaatttgaa gaacaaaaag cagcaatgat gtacatggga
    18001 acttggtata tggctggcat actcgcaaac aaagaagcaa gtaagacaga agtagaatgg
    18061 ggaattacag ctattcctca gaagaaaaaa ggagaatcgg tcacgacgtt tggctcacca
    18121 acagcatttg ctgtcaataa aaactcaaag aaacaaaaag cggcgcaaga atttattgaa
    18181 tttgcagcca gtgaagaagg agcaaaagta ttagcaggag taggagtagt tccttcatat
    18241 cgtacggatg agattgatca gctttatttt aatctcgctg gaatgccaac ggatgaaatt
    18301 tctaaaaaag ctttttctcc tgatgaaatc aaacttgaat ttccgattga tacgtatggg
    18361 cctgcaatcg ataagatttt acaagaagaa tatgacttag ttttggttgg agatgaaacg
    18421 ccggaaaaag gaacggtaaa tatggagaaa cgtgtagctg cggaaaaaga ataatcatga
    18481 aaggagagaa gccaagagat aaaacactct tggtttcgtc atcgaaatgg agaatagtat
    18541 aaataagaaa gctacaaatc atttgcgtag aaaacgaacg tggatcgctt attcgtttat
    18601 cgccccgaat ttcattggtt ttttcgtttt tacattaata ccaatcctgt tttcgcttgt
    18661 actagcattt atgaaatggg attctttttc aacgccagaa tttgctggac tagataactt
    18721 tcgtaaaatg gccaacgatg agacattttg gatttctttg aaaaatactt ttttatatac
    18781 cgctgctgta gtgcctggca cacttgtttg ttcgttaggg ctagctttac tactaaatca
    18841 gaaaattaga gggatgaagc tttttcgtac gatatttttc tttccgtatg ttacttcctt
    18901 agtagcaatt gctgttgttt ggaatatgtt gtttcatcca acagtgggac ctattaatat
    18961 ctttttaaga cgatttattg aacatcctcc aggttggact tcaagttcaa attgggcgct
    19021 ttgggcaatt gtaattgtca gtatttggcg agggatgggt tattacatga ttctatacct
    19081 tgcaggacta caaagtatcc aaaaagaact atatgaagcg tcttcgctag atggagcaaa
    19141 ccgttggaaa caatttttga atgtgacatt accttcgttg agaccaacaa ccttctttgt
    19201 aacgatcatg cttgtcatca attgtttcaa ggtgtttgac cttgtgcaag tgatgacgga
    19261 tggcggccct ggtcgagcga caaatgtgct ggtttaccaa atctacaatg aagcattcaa
    19321 aaaatttgat tttggttatg cttcagctat ttcacttgtt ttgttcgtaa ttgttttggg
    19381 cgttacggtt gttcaatttt cttggaataa gcgtcgtact taggaggtgt gatatggaag
    19441 agagtgttcg aaatgaaaga aaaaaagcaa aaattcgttc aaaaaacatg ccctttattc
    19501 aatggttggg tatgattctg ctgattgtat tagctttatt gacgatcatt ccttttttat
    19561 ggatggtttc tgcttcattc aaagcaaata atgaagtgtt aacgattccg attcaatgga
    19621 tccctaaaac ttggcattta gagaattatc tggttatttg gtctcgtatt cctttagtga
    19681 cattttttaa gaatacagct tttttaagcg ttgtgatcac gttgattcag ttgtttactt
    19741 ctagttttgc tgtttacggg ttttctgaac taaattttaa agggcgcgat attttatttt
    19801 tagcatatat cggcacgatt gctgtccctt ggcagtctta tatgatcccg cagttcatta
    19861 tgatgagaaa agtgggttta acagatacgt tgtggtcgtt ggtgctatta caagcgttca
    19921 atgcttttgg tgtgttcttg ttgaagcaat attacagtag tatcccagat tctttatgtg
    19981 agagtgcgcg gatcgatggc ttatcagagt gggaaatcta tcgcaagatc attttacctc
    20041 ttacaaaacc ggcgattgcc agtttgacga tcatcacatt cgttaataca tggaacgatt
    20101 atatggggcc attcatttat ttgtcttcta cggaaaataa aacaatccag ttagggttga
    20161 aaatgtttat tgggctattt gatgcagagt acgcattaat catggctgcc tcagttgttt
    20221 ctgttcttcc tgttgctttt atatttttag cgatgcaaaa atattttgta gaagggatcg
    20281 cttcatcagg aatgaaggaa taggaggtga ttatgaaaga gcagcgtttt gacaaaaatg
    20341 tttatatgga attcttttat tggttgtatc aatcattggc aagtagcctt tgtttttggt
    20401 gtgtcaatat cttgtatata gcagctgcgt tccttttgtc gatagatgga aggaatgtct
    20461 tttcctttat tttttcttta ctttttattg gtccaggttg catcgtgatg ataggtatga
    20521 cagaagaatt agcaaaagaa aaaagttttt caccagtacg tttgttcata aagacgtttc
    20581 gccaattttg gctaaaggga tttttttatt ggctatttgc ttggatagtt agtgtgataa
    20641 tgatttttga ttgtttcttt tttatacgtt tttcttatgg aaaatggttg attccgttgt
    20701 ttgttttact tgcttgtttt acttgcttgt ttatcagttt cctttagcat caactgctgg
    20761 tattttcagg tgagaaatcc agcgtcgaaa ccaaatcaag ttctacggat agcgttctac
    20821 tatacgttga aaaaatggta tgtgagttta ctagattttt tactattgac aagtttgttt
    20881 ctcttctttt tcgtaaagcc ccaatggtgt attctactag gtccttctat cgtatttggt
    20941 ttgatttact tcaacaatcg taaattgatg agaactatgg atctgtagac tttataaatt
    21001 gaaactttca attaagaatg acagtttttt atgtaaaaac tgtcattctt tttcattttt
    21061 tgaaacatat ggctaaacaa atgaaataaa acatgctata cttttgaatg aaacaggttt
    21121 agaaactgta tcacttattt gtgattattt ctaactaata attaaaaata aagcataaaa
    21181 aggacgatgt tcaatggctg aaaaaatgaa acaaggttcg aaatctgtag tagaaagttt
    21241 gattaatcat catgttgatt atgtattcgg tataccaggt gcaaaaatcg atggtgtatt
    21301 taatgaatta gaggatcaag gtcctgaatt aatcgtgact cgtcacgaac aaaatgctgc
    21361 atttatggca caagcaatcg gacgtattac aggagagcca ggagtagtta tcgcaacaag
    21421 tggtcctggt gctagtaact tagctacagg tttggtaaca gcgacagcag aaggtgaccc
    21481 agttttagca attgccggac aagtaaaacg aagcgatcta ttgaagttga cccatcaaag
    21541 catggataat gcagcactgt tccagccaat cacaaaatac agtgcagaaa tccaagatcc
    21601 agaaacaatt tcagaagtga ttgccaatgc ttatcgtatg gctaagagtt caaaaaaagg
    21661 cgcgagcttt atcagtatcc cgcaagatgt agtggatgca cctgtccaag gtaatgtcat
    21721 caagccattg agcgatccta aattaggttc tgcttctgca gatgatatcc gttacctagc
    21781 tgaacgcatt agagaagcaa aactaccggt actattagta ggtatgcgag gatcaagtga
    21841 aaaagaaacg ttagccatca ggcaattagt tgaaaagaca gcattgcctg ttgtagagac
    21901 attccaagca gctggagtga tctcacgtga attagaagcg catttctttg gtcgtgtggg
    21961 tttatttaga aaccaaccag gagatatgct tttgaaacga agtgatctag ttattgcaat
    22021 tggctatgat ccaatcgaat atgaagcaag aaactggaat gcggaaaaag atgcgcggat
    22081 cattgtgatc gatgaagcgc cagctgaaat cgatcctttt atgcagcctg aaagagaatt
    22141 gatcggtgat atctcagcca ctcttgattt attgacaggt tcattagagc ctcaacaagt
    22201 gtcagaagat gcaaaagaat atttagcatc tcttcaagca aaattaacgg agcgggacat
    22261 tgttcaatca aaaggagaag caggtatctt gcatccttta gaagttatta acacgcttca
    22321 gtcaaaagta acagatgata tgactgttac cgtagatgta ggtagtcatt atatttggat
    22381 ggcacgccac tttagaagtt atgaacctcg tcatttgtta ttcagtaatg gtatgcaaac
    22441 gcttggtgtt gcattgccat gggcgatttc tgctgcattg gtgcgtccaa atacacagat
    22501 cgtatcagtt tccggcgatg ggggattttt attctctgcc caggatttag aaacggcggt
    22561 acgtaaaaaa ttgaatatcg ttcatttgat ttggaatgat ggacactaca atatggtaga
    22621 gttccaagaa aaaatgaaat atcagcgggc gtcaggtgta gactttggtc cagttgattt
    22681 tgtgaaatat gcagaagctt ttggcgctaa aggaatccga gctacaagtg tagaggaatt
    22741 agaaaaagct ttagaagaag gatttgcgac agaaggaccc gtaattattg atattccgat
    22801 tgattaccgt gataatgaga aattgggaga aacaatctta ccagatcaat tctattaagg
    22861 aagtgtcgac atgactgaaa aaatcttata ccagcacggg acattaggag ctttgatggc
    22921 cggcttgatg gatggaacag aaacgattgc tcatatatta gaaaaaggaa ctctgggatt
    22981 gggaacattg catgggcttg atggtgaagt catcttttta gatggcgtag cttatcaagg
    23041 aagatcagat ggctcagttg cccaattaga tggaagtgaa cttaccccct atgcagcaat
    23101 tacagatttt acgccagata ctagtttttc tgtctcaaaa actgcagatg gagaacaatt
    23161 gaaaaaagac atattagtaa gagaagccgg ggaaaaccta tttttggcag tgaagataac
    23221 tggattattc aaaaatatgc acatccgtat catgccgaag caagaaaaac cttacagaag
    23281 actagcaaaa atttcagagt ctcaaccaga attccaacaa agcaatgtcc aaggaacatt
    23341 agtcgggttc tttacgcctg aattattcca aggagttgct gcagcgggat ttcacctgca
    23401 ttttatcgat gatacacata catttggcgg acatgtaatg gattttgaag tggctgaagg
    23461 aaaagttgag attagccgca tctcgtccct tgtacagcat tttccagttg atgatccgac
    23521 ttttgttcac gaaacgattg attatgctga tttagcagca gaaatccaac aagcagaata
    23581 gaaaaagaca gcgagatgcg ttcaaggtga ttaacctgac gtatctcgtt tttttgagga
    23641 gaaaacctag cgtttacaaa aaaactgagc tataatcttc tccatagatc aaaaaggagc
    23701 ggtttttatc atgtggacag aaaaacagaa aaaagatgca tacgaaattt tattattaca
    23761 gcaacaagga ttattagaag cagaagataa ctggttagca aatttagcaa attcatctgc
    23821 attgttgaat gagactttgc ctgagactgt ctttgcagga tattatttat tcgatggtaa
    23881 tgaattgatt ttaggaccgt tccaagggcg agtttcttgc acacgtatca agatgggaaa
    23941 aggagtttgt ggagaatcag ctgaaaaaca agaaacattg atcgttgatg atgtcaaaac
    24001 ccatgcaaat tacatttcct gcgattcagc cgcacaatca gaaatcgtag tgccaatggt
    24061 aaaagaaggt aatttaatcg gtgttttaga tatcgattgc ggagtaacga aagggtatga
    24121 tgaaatcgat caagcatttc tagaaaaata tgtagatctt ttattagcaa attttaatat
    24181 aaatgctttt tcatttatta ataactaaaa tcgtctattg aaacaaaaaa gaagagaaat
    24241 caagaataaa aagagccgga aagacagtgg gcatttctgt ttttcggttt ttttattttt
    24301 ttataaaatc acaagtgtta ttgattttca taatcatatt ttaatgttat tatcatttta
    24361 aataatgaaa aaacattaag gatggatgaa atatgaataa cgaaactatc attttaggaa
    24421 aaaaatatat ttgccaacct attggcttga aacaaaaagt gattggagaa gtaatcagta
    24481 aattagaaaa ttgtgttgtg atctgcgtag acgaatatca tgacgtcgat cgcaatgaaa
    24541 tattagaaaa atgcggaaaa gtagtggcaa aatatactca cgtttatgag ttggaaacaa
    24601 cagaatatct atataactat agcaacaaat atgaacatac tttagtttca taaagattta
    24661 aataaagtgc cttcaaaagc gagaagacca agcttttgaa ggcactttat ttagttggca
    24721 gtgattgttc atgatttttg atttattcaa aaggttcgcc tagagaatct gtctctgtaa
    24781 cgaggcctgg tggagaaact cgataaaaac ctatactgcc agaactgtcc tattttcgga
    24841 tagacaaact agtagtttta aaaagatcat ccgatccaat catttcaaaa aatgcaaaac
    24901 tgatatcagg atcatttagc tcaggcttgt tatcgtaaag catttgtaaa ggttgcattt
    24961 agttaggagt aaacgcgaaa ctatcatcat tatttgctga agaagatgaa gaagctaatt
    25021 cagagtttgt ttgaaataaa ggagacgtgc tgacagtttc tttaccctgt tttttgcaga
    25081 ggtagaaact tttatatcgg aagtttctac cggagaattt ttctcatttg tagaaattgt
    25141 tgaatcgata ctattcgaaa tttgcgtatc tgaaggtatg ttctttgatg cagaagtccc
    25201 acaagcagta agtaacaata aatttgataa actgataaac agaattcttt tcattatgta
    25261 cacactcctt atagtatcgt ttagcataca cctatgctca gtattaggca aaatcaatgc
    25321 aaaactatca agtcttttat agtatctatt agtcttagta atacatatat ggagagggtg
    25381 atatcccagt tcaaaccaga tacattggtt accatctgta ttaacgatta tgcctctaaa
    25441 cgcttttttt atgaaaaaat ttataagtga aaacgtaggt atgatattat ctagaggtaa
    25501 tttttttggg tatttaaata gttgctagga ggatagcttt tggattttta cagtaatttt
    25561 atcttaataa tagcaatatt attacttcta aatatttggt tttttgataa gagtagaaat
    25621 gcagggatag gttttagaac caaacgaagt acgtcttctg aaaaaaagtg ggtatattca
    25681 cagactattt tttacggagg ggttatttca atcagtttac tttcttcaac actttattct
    25741 tttaatgtta tagacgtttc catgtcaaat tttatatcta ttattggaat ccttatttct
    25801 gcaattatta cacaactact tcttgtgttt gaagagaagt caaaaaataa ttaaagcaat
    25861 tatgcctttt agtacaggaa ttattacttc ttacaaatgt atagcgaatg tgaagcctgc
    25921 tgttttaatt gttctagaaa aacttttgag tgaacaatta ttttatgtta ggatgaatta
    25981 atttctctag agtttata
//
LOCUS       DAYNVV010000037        25523 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.037, whole genome shotgun sequence.
ACCESSION   DAYNVV010000037 DAYNVV010000000
VERSION     DAYNVV010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25523
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.037"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..205
                     /locus_tag="ACGXWR_001742"
     CDS             <1..205
                     /locus_tag="ACGXWR_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HFK0803300.1"
                     /translation="YQHHLTKSRKTVETVFSSLEKLGCQNFNSRSVKGLESRFESILL
                     AYSVLLSRAQRRFEGTLRYSLGY"
     gene            complement(340..855)
                     /locus_tag="ACGXWR_001743"
     CDS             complement(340..855)
                     /locus_tag="ACGXWR_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HFK0803301.1"
                     /translation="MVVVMVKVFDIIKFSDFRGYTAVALDNETLFSIGIEFHIKQINQ
                     GFSHNKYTMRGLHYQSGEHAQGKIVMCLHGEIMNIALDIRQGSSTYGCVYVNTLSESN
                     GKCAYIPRGYAHGYLTMEDNTLVQWCVDNDFNSNAAKCISYESVDIEWPVSRQCFVIS
                     EKDKNVERLSF"
     gene            complement(1037..1648)
                     /locus_tag="ACGXWR_001744"
     CDS             complement(1037..1648)
                     /locus_tag="ACGXWR_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFK0803302.1"
                     /translation="MIDIISAITVNVLTALYQPFLFAVLTAYLFMYWYLFIVDNSRDP
                     KNLKDSVLIWLRYFKASSKFRRLFFLAFYFTLILFKTLLNRNMWMNPLSNVIGQWSLY
                     IIDNATGESRLTTECVENTMLFIPFCMLLLWWRDIKCDIIRTIYVGIKYVFLFSLSIE
                     FTQLFFRLGTFQLSDLFYNTLGGLIGALLYWLFYRLNKYIDLK"
     gene            complement(1674..3125)
                     /locus_tag="ACGXWR_001745"
     CDS             complement(1674..3125)
                     /locus_tag="ACGXWR_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFK0803303.1"
                     /translation="MTSNNLIVKTLSRYKNTPLPVKAALWFMVCGFLQRGVSMITTPI
                     FTRVLSTEQYGLYSTYLSWESLLLMITSLSLFKAMMNLYVKYDNQEHILSTVSGLTLV
                     LTIFWFVIAIFIKDILAEILGLTPVLVVCMFSYFIFQAEIQCWSLHKRYIYDYKTLLV
                     ATLAVTVGSSVVGCLAVLFISPTAEARALMNVLVTGVVGVAVYISVFRRCKDFKDNEV
                     WNFAVVFCVSLMPHYLSEFILNGSDKIMINYLCGSSDVAIYSVAYSIGALINLVTNSV
                     NSTFAPYQYQKIKSGEYDLLSKRANEVLGLVAAMLFALMLFSKEIVLIFGGQKYIDSV
                     NLIVPICIGIYFNYMFQLFARVQEYFEKKLTVVIPSVLCAIMNIVLNYVFIKLYGYQA
                     VAYTTVFSYMFFCVIHYIFYRKVCKELLDGKNIYDVRGILLISAITIAGGILISIINK
                     FDFIKYLIIAIACVAAIIFRKRLLLLVRRIMSK"
     gene            complement(3149..3880)
                     /locus_tag="ACGXWR_001746"
     CDS             complement(3149..3880)
                     /locus_tag="ACGXWR_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFK0803304.1"
                     /translation="MEKKMTVIITMAGLGSRFRKIGYAVPKYMINAKGRTLFDWAMDS
                     LVGYNKNVDKYIFVVRQEDNASAFIKEHCAYFGIENVEVIEIDYMTDGQATTCMLAIP
                     YCNQDNEIMVYNIDTYVESNEMKYEDICGDGHIPCFHADGDHWSFAKLNDRNEVIEVR
                     EKVRISDNCTLGAYYFSSAKLYKALYEEYYADSSNMEKNEKYIAPLYNFMIKKGLKVT
                     ISIVDAKKVHVLGTPEELNVFLNQE"
     gene            complement(3898..4293)
                     /locus_tag="ACGXWR_001747"
     CDS             complement(3898..4293)
                     /locus_tag="ACGXWR_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HFK0803305.1"
                     /translation="MYSEYSFVFDIDGTLCPIKKKDERYEDLVPYENMVEKLRFYKEN
                     GAKITLFTSRNVNSYKGNLGMINANTAKVLLAWLDKWDIPYDEILYGKPWPGHKGFYV
                     DDRTVRPDEFLRCSVDELNEICNSSKKRF"
     gene            complement(4395..6032)
                     /locus_tag="ACGXWR_001748"
     CDS             complement(4395..6032)
                     /locus_tag="ACGXWR_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HFK0803306.1"
                     /translation="MKVLIPAAKVVEKELQSIGMLPAIIYPINKKIVFDYLYNQYNAI
                     CDSLDIICYEKADKVHRRLKNYHDSRIHICDLPELGDLGQTVYFGLSDEDEPVLINFA
                     DTIVMESMSDIEMDTFYYSEDFVSSTWTYFKINEGIITDIHDKEEAYVSDKREKLFIG
                     VFMFSSSKLLKSCLREAVESRKQGGINSFYRALQLYSERCPLKAVRTEKWFDIGHIDK
                     YYNTKLEVKAREFNHISIDKDRGILKKTSDDKDKFIGEIKWYLKLPADIEYVRPRIFD
                     YSTSYVAPYVDMEYYAYHTVHELYLYGDLKYNQWHDLFSRIKFICSDFKRYTLKDEKI
                     RESLEDMYLRKTMQRFQKLSEDKRFSAFFEKQIQINGRKFISLTGVIELLKNLIPSML
                     YDVNEFCIIHGDLCFANMMVDSNCSFVKVIDPRGKFGKYDIYGDSRYELAKLFHSLDG
                     KYDYIIKDLFTVEYDTECAVIDYTINTRVRDYDLFELFKSVFSDEIKDDFDKIVLIEA
                     LLFLSMIPLHGESFDHQIVMLATGMELLARVSNKVIL"
     gene            complement(6067..7401)
                     /gene="gmhB"
                     /locus_tag="ACGXWR_001749"
     CDS             complement(6067..7401)
                     /gene="gmhB"
                     /locus_tag="ACGXWR_001749"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HFK0803307.1"
                     /translation="MKTVIMAGGRGSRISELFPDIPKPMIPIDGIPVLERELCSLRDQ
                     GFNDIILTVSYLHEKIEEHFGDGSKLGIKIKYFIEKTPLGNAGALYFLLDELGDEPFL
                     LLNADAVFDVDFRQMIRFHVENNADVTLFTHPNSHPYDSGLIISDDNKKVLQWLAKED
                     QRPEYYKNRVNAGLHVINPKVLRENPLMEIVNKSIVEGGGLPYKIDLDRMILKPLANT
                     GRMYCYDSPEYVKDMGTPDRYRAVIKDFQKGIIVGKNLSNPQKAIFLDRDGTINKYVG
                     FLRNAEEFELIDGVSEAIKIINSLGFLCIVITNQPVIARGEVTVDELNSIHNKLETML
                     GHAGGFLNGIYYCPHHPHKGYAGEVIELKIDCNCRKPKPGLLLEASKDFNINLSQSFM
                     VGDSESDVIAGKNAGCKTVLITEDITLPANYGQDYSVCSLLEFVKNHLCTMQ"
     gene            complement(7443..8552)
                     /locus_tag="ACGXWR_001750"
     CDS             complement(7443..8552)
                     /locus_tag="ACGXWR_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WavE lipopolysaccharide synthesis family
                     protein"
                     /protein_id="HFK0803308.1"
                     /translation="MNKKEILYNILKKYENLPYVFRNMFGHNISKLVSWKLTADCATV
                     EENSEVYAAFQLRSKDMSDVPVMGLVNCCKDVAIVMQGPLCLKDDFSYNTLAYYKKCY
                     PNALIILSTWKDEDIKALKRIEDLGVIVICSEKPEKPGHLNINYQVGNTLPGIVRAKQ
                     LGAKYVCKTRTDQRIYHPNAMAFFCSLLEQYPVNNEDDWKLIQNQRLLLLSMPYGDMF
                     FPYCLSDFLYFGDVDDMINLFSIPSDVREKGAVSRGVSRREISENNLAPEVQLLRSYI
                     SRMGGNEECSIRAYWEFVKNHVITINKNQIDLYWHKYVGRYSNNTIYGTYYIDDSQDA
                     LHCYNFDFINWLNLYTGKYEYKAEYEKYMDFVWEE"
     gene            complement(8577..9710)
                     /locus_tag="ACGXWR_001751"
     CDS             complement(8577..9710)
                     /locus_tag="ACGXWR_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803309.1"
                     /translation="MNVRLVTVILAIVCLLIASLPAFRKNRYLNFCTLLICVVIIAAY
                     IYSDKTIWVKSRESMSLYYVLLAYPLFCTLINQAWNLDSMLNTICGVTFLSYILRTSI
                     SLIQKFSGVLLYENIYRECAPENWYRGGFLRINPPCFTIIIIPIALYMIERQVVARRK
                     VKYYLLIASALAYSAVIHGSRSVLVYQIIVLGCYILFKKGSSKRKIAMWVLAGLLVVI
                     FINSTMFSTFVETFTNSTGEYAGSAESRFASVWFFIPKFLQSPLFGTGILTGEEFTFI
                     LPGGVRGHLSDIGFFYTITQYGVGILIFDILFIIKGFKTALLASKVGMTGYQYLAFGI
                     TLNVLLTGINIDWFYPIFTPAIPVCLAVIEYIYQECRSVANIE"
     gene            complement(9843..10949)
                     /locus_tag="ACGXWR_001752"
     CDS             complement(9843..10949)
                     /locus_tag="ACGXWR_001752"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFK0803310.1"
                     /translation="MKVLMCESQMPENWYSFDLSKELNQYVDLTLLCKRDVPPLDPKI
                     KSKHILYHKSTNKVFSALVFLKSLFLIWKEIRFGDYDIVHLQLMKSLKYEGGLYVLCK
                     RHYKKLIMTVHNVLPHEVREKDRQEHFNIYSNCDGFIVHNRVTEQHLYAEFPELNAKS
                     YVCPHAIYGDVKHISRAYDKDKFEFILFGQIRPYKGIDVLLNAITELPMDVRKKVHFT
                     IAGQQHPKQDSTDYKKMIEDLKVSDCVLYKPERISDEEMDSMFRNADAAIFPYKEIYG
                     SGALLMAYTYCLPTIVSNVPAFMEETEEGKIGLLFENLNSKSLADTIVKYVNLSPAEK
                     SKIEDDIYELVNRKYTWAASAKLTYEAYKQILNE"
     gene            complement(10960..11733)
                     /locus_tag="ACGXWR_001753"
     CDS             complement(10960..11733)
                     /locus_tag="ACGXWR_001753"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family A protein"
                     /protein_id="HFK0803311.1"
                     /translation="MLYFVIPLMSAKAANNWEMVSTLFNRTLWSCYNQTDPDFKIIVA
                     CHEIPKLTHEYDDRVEFIQVSEKDAPIPTNQDEKMIDKGYKTHALAMRLRELGGGFAM
                     MVDADDLVSSHLAEYVNSHPQENGFYVKTGYVYFVGDDYMKVLPKFSSGSACIVKYAV
                     EDLPEAYPEVMTANCDDNPWIIRKRHGGVVPACEEQGRPLKPLPFKAAVYVLGTGDNH
                     SLYGKTTKYQTKMREILEMFIAKRKIKGKLKAEFSVDWL"
     gene            complement(11747..12202)
                     /locus_tag="ACGXWR_001754"
     CDS             complement(11747..12202)
                     /locus_tag="ACGXWR_001754"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HFK0803312.1"
                     /translation="MNAYKLYKVERWFYLHKMEFFAKIVKALIYVLHNSSISYQTEIG
                     DNCKFLYGGIGCVIGKDTKIGNHVIIGTNVLTGGRSNKPGMPTIGNNVYIATGAKILG
                     NITIGDNVIVGANAVVINDVEPNCSVGGVPARVLKKDIDVNDYCSLNRY"
     gene            complement(12624..13730)
                     /locus_tag="ACGXWR_001755"
     CDS             complement(12624..13730)
                     /locus_tag="ACGXWR_001755"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFK0803313.1"
                     /translation="MKILIVVTMTNNFGKKGSYNSQEIGLARGLAELGHEVIVYKSVK
                     SDEEVGTEQLSNTAMIHYIKCRYVGSNGFLSTKNFDKNADVLIQFADLQLSVPHVYSW
                     TVKNGIKYIPYNGITRSQSGNKYIKTIIEILAHRNYKIYKKNGCVAKNDRVSEKLVQL
                     GVNKVKLAPVCVDFEQLHKNYEAIDFTTLREKWNIPRNVRVILYVGRFEKDKRPLDMI
                     SLFNKLDEHNYLLMVGTGALLEQTKQQINLLGLQNRVKIIERIPNKDIWELYCLSDVF
                     VNLNYTEIWGMVLLEAMYYRLGIIAVNAPGPQNIILDNRYGMLAKSDDEILTFLKDGR
                     FTNDIIDAAYQRVTTEFRWSKSGEIMLSMLEGDK"
     gene            complement(13748..14509)
                     /locus_tag="ACGXWR_001756"
     CDS             complement(13748..14509)
                     /locus_tag="ACGXWR_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HFK0803314.1"
                     /translation="MEKNMYKRKRDFTVCGIVGVCATTKNEFVREVFSMPTSPVSATV
                     DLVGVPAIISAKENPKIAEMYSQATMAAIDGMPIVKIGRRKGFTCERCAAPDIMGMVF
                     EEGVRQGKTHYFYGGKDNEVLNKLRANLERDYPGIKIVGMYSPPFRPLNEEEDSKICE
                     EINNLNPDFLWVGIGAPKQEMWMWEHQKKIHNTVMFGVGAGFNFFAGTLEKAPEWMEK
                     ASLEWLFRLVKEPRRLWRRYILGGIKYIYYTIESK"
     gene            complement(14585..15583)
                     /locus_tag="ACGXWR_001757"
     CDS             complement(14585..15583)
                     /locus_tag="ACGXWR_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFK0803315.1"
                     /translation="MKKTIMVTGGCGMIGSNLVKRLVKEGCWDVYVADNLWRGKLEYL
                     NDEDGHPVIDLDTHFFNADLTDYEQAKKVIGTTEYVVHLADVVAGIDYVFKNQGELFR
                     INNLINSNVFDCCRKAGKEKIKGVIYVGTVCSFPLTRQNTLNPEPLREEELFPALPES
                     AYGWSKLMGQLEMGYLEKETGIPCCILMLHNVYGTPTDFGERSQVIPALIRKAINNPE
                     EPFNVWGSGEQGRAFIHVNDIVNALVLALDKGWGHGHIQIGPSHCTSIKEIAYKIIEI
                     SGKDIKPFFDTSKPEGDKARCADYSKAKEILDWEPTVSLEEGLRESYNWIEKQIKG"
     gene            complement(15602..16255)
                     /locus_tag="ACGXWR_001758"
     CDS             complement(15602..16255)
                     /locus_tag="ACGXWR_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFK0803316.1"
                     /translation="MLAEKLNKHIDLLIKRYPTLETIKQDIIDGYLIMEECYLNGGKL
                     LVAGNGGSAADSEHIAGELMKRFKTPRPVSKEFADKLVAIDPVRGPELAKNLECGLTA
                     IPLVAHEALSTAYINDVDGLGVFAQQLFGFGRSGDVFLGISTSGNSKNIMSATVVARA
                     LGIKVIGLTGAKGGELATVADVCVKAPEVETYMIQEYHLPIYHCWCLMLEDKFFGNE"
     gene            complement(16265..17275)
                     /locus_tag="ACGXWR_001759"
     CDS             complement(16265..17275)
                     /locus_tag="ACGXWR_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HFK0803317.1"
                     /translation="MIITKTPFRMSFFGGGTDMEDYFKENGGAVLSTTFDKYCYVNVR
                     HLPRFFDYSAELSYSRTERVTSIEDIEHPAIRNAMKMLDMHEIRLTYEADLPARSGLG
                     TSSSFAVGMLNAFYALEGKYADKKKLADEAIYLERVLCNEAGGWQDQIAASYGGFNRI
                     NFNVDGYEVLPVIISPERKKQLNNNLMMFFTGFTRFSSDVQKANNVSGTEDKRVRLKK
                     MYELVDEAEAILTDKNRNLDDFGRQLDVTWRLKKGTGGAISTGSIDELYEKGMAAGAL
                     GGKLLGAGGGGFLVFYVQPEKQDAVRWAMRDLMYIPFEFENGGTRVIHYTPETYIEKQ
                     NG"
     gene            complement(17294..18544)
                     /locus_tag="ACGXWR_001760"
     CDS             complement(17294..18544)
                     /locus_tag="ACGXWR_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HFK0803318.1"
                     /translation="MKKQYNIAVAGTGYVGLSIATLLAQHHKVTAVDIIPEKVELINN
                     RKSPIQDDYIEKYLAEKELNLTATLDAKAAYQSADFVVIAAPTNYNSRTQHFDTSAVE
                     AVIRLVMEVNPDAIMVIKSTIPVGYTASVRVKTGSKNIIFSPEFLRESKALYDNLYPS
                     RIIVGTDMDDERLVEDAHTFATLLQEGAIKENVDTLFMGFTEAEAVKLFANTYLALRV
                     SYFNELDTYAEMKGLNTQQIINGVCLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYA
                     DVPENLIEAIVESNRTRKDFIADRVLQMAGYYNYAEANQYDAGKEKPVVIGVYRLTMK
                     SNSDNFRQSSIQGVMKRVKAKGATVVIYEPTLKDGETFFGSKVVNDLEQFKAMCDSVI
                     ANRYDACLDDIKEKVYTRDIFQRD"
     gene            complement(19051..19331)
                     /locus_tag="ACGXWR_001761"
                     /pseudo
     CDS             complement(19051..19331)
                     /locus_tag="ACGXWR_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003697748.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
     gene            complement(19890..20000)
                     /locus_tag="ACGXWR_001762"
     CDS             complement(19890..20000)
                     /locus_tag="ACGXWR_001762"
                     /inference="COORDINATES: protein motif:HMM:NF020874.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HFK0803319.1"
                     /translation="MNPNGYEWLRAKGSYPVPKYCNYSETLMEWYQLIIT"
     gene            complement(20406..21095)
                     /locus_tag="ACGXWR_001763"
     CDS             complement(20406..21095)
                     /locus_tag="ACGXWR_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFK0803320.1"
                     /translation="MESEDLLSRISEVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYVAYRIRKEEPGSPIFFCHTRVGKNGKTFKMYKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTKIGKIIRAKSIDELPQLWNVLKGDMSLIGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSDRNNVSFHKMVELDLEYISHRSLMYDLRLILKT
                     FYVIVKPNGAY"
     gene            complement(21140..21904)
                     /locus_tag="ACGXWR_001764"
     CDS             complement(21140..21904)
                     /locus_tag="ACGXWR_001764"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsB/CapC family capsule biosynthesis tyrosine
                     phosphatase"
                     /protein_id="HFK0803321.1"
                     /translation="MIDLHCHILPGIDDGAENIDASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIDRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEQLFFELLQLGKTPVIVHPERNAHFRKDPNHMLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKMMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            complement(21932..22630)
                     /locus_tag="ACGXWR_001765"
     CDS             complement(21932..22630)
                     /locus_tag="ACGXWR_001765"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0004715 - non-membrane spanning protein
                     tyrosine kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HFK0803322.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENMSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(22643..23422)
                     /locus_tag="ACGXWR_001766"
     CDS             complement(22643..23422)
                     /locus_tag="ACGXWR_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YveK family protein"
                     /protein_id="HFK0803323.1"
                     /translation="MEETISLKEIFETLRKHVITILISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQATSTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAPIQPKATNDKTAPSRRSRSRV"
     gene            complement(23438..24382)
                     /locus_tag="ACGXWR_001767"
     CDS             complement(23438..24382)
                     /locus_tag="ACGXWR_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFK0803324.1"
                     /translation="MAKRRRRSRGKKIFLIILAILVVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGHDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYRDAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(24423..25202)
                     /locus_tag="ACGXWR_001768"
     CDS             complement(24423..25202)
                     /locus_tag="ACGXWR_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803325.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHFNNQRQHHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSLIEQIRNEKIRAAYASKAETVAQQMGYSNTSY"
BASE COUNT         7875 a         5469 c         3744 g         8435 t
ORIGIN      
        1 ttaccaacat catttgacaa agagccgaaa aacagttgag actgtttttt cttccttaga
       61 aaaattaggt tgtcaaaatt tcaactcacg ttctgttaaa gggctagaga gtagatttga
      121 aagcatatta ctggcttaca gtgttctatt aagtcgagca caacgacgtt ttgaaggaac
      181 tttgagatat tctttaggat attaaaatta actagcacca cgggtatatc tatatctaaa
      241 tttagtttta tgtattcctc atagaaataa ccgagcattt gctcggttat tgttcttctt
      301 attttccagt atccttcttt tctccacagc tcattttaat caaaagctta atctttccac
      361 atttttgtct ttctcactta taacgaaaca ctgccgactg accggccatt caatatctac
      421 gctttcataa cttatacatt tggcagcatt agaattgaaa tcattatcta cgcaccactg
      481 aactagcgta ttgtcctcca tagtaagata gccatgagca tatccacgtg ggatatacgc
      541 acatttacca ttgctttcac tcaatgtgtt gacatacaca catccataag tggaagatcc
      601 ttgtcgaata tcaagtgcga tattcataat ttcaccatgt aggcacatca ctatctttcc
      661 ttgagcatgc tctccactct gataatgtag ccctcgcata gtatatttat tatgactaaa
      721 tccttgattt atttgcttaa tgtgaaactc aataccaatc gagaaaagag tctcattatc
      781 caatgcaaca gcagtatatc ctctgaaatc cgaaaactta attatatcaa acacttttac
      841 cataactacc accatgttat atattttacc aattttttaa ttcgctcgac ctcatttaaa
      901 gcaataaaat tccctacctc ttgaagatat aacaacaatg ttttagcaaa aatagatggc
      961 atgtaaagta ttcttgatga gattacacaa tcctgtctgc agaaaaatat taaccatatt
     1021 aaaattcaaa gcagttctat tttaagtcta tatacttatt taatcggtag aatagccaat
     1081 atagcaaagc accaattaag ccccctaggg tgttataaaa caaatccgat agttgaaatg
     1141 taccaagcct aaaaaacagt tgtgtaaatt ctatacttaa tgagaataaa aacacatact
     1201 taatcccaac atagatggtg cgtataatat cacatttaat gtcacgccac cataacaata
     1261 acatgcaaaa agggataaac agcatcgtgt tctccacgca ttctgttgtc aatctgctct
     1321 ctcctgtagc attatctata atatataatg accactgtcc aataacgttt gaaagcgggt
     1381 tcatccacat atttcgatta agcaaggttt taaataatat caaagtaaaa taaaacgcaa
     1441 gaaaaaagag tctgcgaaat ttactagatg ctttaaaata tctcaaccag attaatacag
     1501 aatcttttaa gtttttagga tctcgagagt tatcaactat aaatagatac cagtacataa
     1561 acagatacgc tgttaatacg gcaaataaga acggctgata taatgctgtt aatacattta
     1621 ccgttatagc agaaataata tctatcattc tctatctctc tatgagcaaa tgtttatttg
     1681 ctcataattc tccttactaa aagtagcaat cgttttctaa atataattgc agcgacacaa
     1741 gcaattgcta taattaaata ttttatgaaa tcaaatttat taattattga aattaggatg
     1801 ccaccagcta tcgtgattgc agaaatcaaa agtattcctc tgacatcata tatgtttttt
     1861 ccatccaata gttctttgca aacttttcta taaaaaatat aatggatgac gcagaaaaac
     1921 atatatgaga atacagttgt gtatgctacc gcctgatacc catataactt tataaaaaca
     1981 taatttagta caatattcat aattgcacac aaaaccgatg gaataacgac agtgagtttc
     2041 ttttcaaagt attcctgtac tctagcaaac agctgaaaca tatagttgaa ataaataccg
     2101 atacatatag gtacaattaa attaacactg tcgatatatt tctgcccacc aaatatcaac
     2161 acaatttctt tactaaatag cattaatgca aaaagcatag ccgctaccaa accaagaact
     2221 tcattagctc tttttgatag taaatcatat tctcctgact tgattttttg atactgataa
     2281 ggtgcaaaag tggaattgac agaatttgta acaaggttaa ttagagcacc aatagaatat
     2341 gccacgctgt aaatagcaac atctgacgaa ccacataagt aatttatcat aattttatca
     2401 gaaccattca gaataaattc agataaatag tgtggcatca acgatacaca aaatactact
     2461 gcgaaattcc acacttcatt atccttaaaa tccttacatc ttctaaatac cgatatatac
     2521 acagccacgc caacaacacc agtcactagg acattcatta aggctctcgc ctcagcggta
     2581 ggagatataa acagaaccgc taaacagcca actacagatg agccaacagt aactgcaagg
     2641 gtagctacta ataaagtctt ataatcatat atatatcgtt tgtgtaaaga ccaacattgt
     2701 atttctgcct gaaatataaa atatgagaac atacagacaa ctagaactgg tgtcaatcct
     2761 aaaatttctg ccaatatatc cttaataaaa atagcaataa caaaccaaaa aatagtcagt
     2821 actaaagtca atccggatac tgtcgaaaga atatgttctt gattatcata ttttacataa
     2881 agattcatca tggctttgaa caaactaagc gatgtaatca tgagcaataa ggattcccac
     2941 gatagataag tgctgtataa accgtattgt tctgtagaca aaactctagt aaaaattggg
     3001 gttgtaatca ttgaaacccc tctctgtaaa aaaccacata ccataaacca taatgcagcc
     3061 ttaacaggaa gtggagtatt cttatatctg cttaatgttt ttacaattag attattactg
     3121 gtcactgcta ttttctccta aacactattt attcttgatt caaaaacaca ttgagctctt
     3181 ctggagtacc aagcacatga acctttttcg catctactat gctaatagtc acctttaacc
     3241 ctttttttat cataaagtta tataatggtg ctatatattt ttcattcttc tccatattag
     3301 aggagtctgc ataatactct tcatataaag ctttatacag ctttgccgat gagaaataat
     3361 acgcaccaag agtacaatta tcagaaatgc gaactttttc gcggacttct attacttcat
     3421 ttcgatcgtt aagctttgca aaactccaat gatcgccatc agcatgaaag catggaatat
     3481 gtccatctcc acaaatatct tcgtatttca tctcatttga ttccacgtat gtatcaatat
     3541 tgtaaaccat aatctcattg tcttgattgc aataaggaat agccaacata catgtagttg
     3601 cttgaccatc tgtcatatag tctatttcaa tcacttctac gttttcaata ccaaagtaag
     3661 cacaatgctc ctttataaaa gctgaagcgt tgtcttcctg acgaacaaca aaaatatact
     3721 tatcaacatt tttattgtat ccaaccaaac tatccatggc ccaatcaaat aaagttcttc
     3781 ctttggcatt aatcatatat ttaggaaccg cataaccaat ttttcgaaaa cgacttccca
     3841 aacctgccat cgtaatgata actgtcatct ttttttccat agaactaacc tccttattta
     3901 gaatcttttt tttgaactgt tgcagatttc atttaattca tctacagagc atctcaaaaa
     3961 ctcatcaggt ctaaccgttc gatcatctac atagaagcct ttatgccccg gccaaggctt
     4021 accatacagg atttcatcat acggaatgtc ccatttatcc aaccacgcca agagcacttt
     4081 tgcagtatta gcatttatca ttcccaaatt tcctttatag gaattaacat tgcgtgaggt
     4141 gaacaatgta attttagcac cattctcctt atagaatctc agtttttcaa ccatattctc
     4201 atacggcacc aaatcctcat atcgctcatc cttcttcttt atcggacaca aagtgccatc
     4261 gatatcaaac acaaaagaat attcactata catttttctc ttcccttcta ttgtattaat
     4321 taatataatc gtgccttaat gcctacattg ctaaaacagt attgtaaccg ttattcatta
     4381 aggcacaatt tatattagag tataacttta ttacttactc ttgcaagaag ttccatacct
     4441 gtagcaagca tcactatttg gtgatcaaaa ctttcaccgt gtaatggaat catactaaga
     4501 aatagcaacg cttctatcaa tacaatctta tcaaaatcgt ccttaatctc gtccgaaaag
     4561 accgacttaa acaattcaaa taaatcgtaa tctcttacac gcgtattaat tgtataatct
     4621 atcactgcac actcggtatc atattctaca gtaaatagat ccttgatgat ataatcatat
     4681 ttaccatcta aactatgaaa tagttttgct aattcatatc tgctgtcccc ataaatatca
     4741 tattttccaa attttcccct aggatcaata accttaacaa aggaacaatt ggaatctacc
     4801 atcatattag caaaacacaa atctccatgt ataatacaaa attcatttac atcatagagc
     4861 atacttggga taagattctt tagaagttca attacaccgg ttaaagaaat aaacttacga
     4921 ccattaattt gaatttgttt ctcaaaaaaa gctgaaaatc ttttatcttc agacaatttt
     4981 tgaaatctct gcatggtttt tcgcaaatac atatcttcca atgactctct aatcttttca
     5041 tcttttaagg tgtatcgctt aaaatcgcta cagataaact ttatacggct aaacagatca
     5101 tgccactggt tatattttaa atcaccatat aagtataact catgaaccgt atgatatgca
     5161 taatattcca tatcaacata gggagctacg taagatgtag aataatcaaa aattctaggt
     5221 cttacatatt caatatcagc aggaagtttt aaataccact ttatttctcc aataaattta
     5281 tccttgtcat cgctagtttt cttcaatatc cctcgatctt tatctataga gatatgatta
     5341 aactctcgtg ctttaacttc caactttgta ttgtaatatt tatcgatgtg tccaatatca
     5401 aaccactttt ctgttcttac ggcctttagc ggacaacgtt cgctgtatag ctgtaaagcc
     5461 cgataaaatg agtttattcc cccctgtttc cgactctcaa ctgcctctct taagcaactc
     5521 ttcagaagtt ttgacgaaga aaacataaat acgccaataa ataatttttc acgtttatcg
     5581 gatacgtaag cttcctcttt atcgtggata tcagtaatta ttccttcatt aattttaaag
     5641 tatgtccaag tactcgacac aaaatcttca gaataataga atgtatccat ttctatatca
     5701 gacatactct ccataacaat tgtatctgcg aagttaatta gaacaggctc atcttcatct
     5761 gataacccaa aatacacggt ttgccctaga tcccctaatt caggaaggtc acatatatga
     5821 attctggaat catgatagtt tttcagtctt ctatgaacct tatccgcttt ttcataacag
     5881 ataatatcca atgaatcgca gattgcatta tactgattat acaaataatc aaagacaatt
     5941 tttttattaa ttggatagat aattgctggt aacattccta tactctgcaa ttctttttca
     6001 acaacttttg ctgctggaat taataccttc atctaattac tccttttaca agtttcacta
     6061 aaccaattat tgcatagtgc ataaatgatt tttaacaaat tctaacaatg aacagacact
     6121 atagtcttgg ccataattag caggcaaggt gatgtcttct gtaatcagta ctgtcttaca
     6181 accagcattt tttccagcaa ttacatcact ttcactatct ccaaccataa atgattgact
     6241 taggtttatg ttaaaatcct ttgatgcttc taataacagt ccaggttttg gcttgcgaca
     6301 attgcaatca atttttaatt ctataacctc tcctgcatat cctttatggg gatggtgcgg
     6361 acagtaataa ataccgttta aaaatccacc agcatgccct agcattgttt caagcttatt
     6421 gtgaatacta ttaagctcat caacagtaac ttcacctctt gcaattacag gctgatttgt
     6481 tataacaata cacagaaaac ctagagaatt aataatttta attgcctccg atactccatc
     6541 aattaactca aattcttctg catttctcaa aaaaccaacg tatttattaa tcgttccatc
     6601 tctatctaaa aagattgctt tttgtggatt ggatagattt ttaccaacaa taattccctt
     6661 ttgaaagtcc ttaattacag ctctatatcg gtccggtgtt cccatatctt taacatactc
     6721 tggagaatcg tagcaataca tacgccctgt gttagccaat ggtttcagaa tcattctatc
     6781 taaatcaatt ttgtatggta gccccccacc ttcaactatt gatttattta caatttccat
     6841 taatggattt tctctcaaca ccttcggatt tataacatga agacctgcat ttactcggtt
     6901 tttataatat tcaggtcttt gatcttcctt cgctaaccat tgaagcactt tcttattgtc
     6961 atcggatata attaatccac tatcatacgg atgtgagtta ggatgcgtaa acaaagtaac
     7021 atctgcgtta ttctcaacat gaaatctaat catctgcctg aaatcaacat caaatactgc
     7081 atcagcattc aaaagtaaaa acggttcatc acccagttca tccaacaaaa aatacaatgc
     7141 acctgcattg ccaagtggag ttttttcaat aaaatatttg attttaattc ctaattttga
     7201 accatctccg aaatgctcct ctattttttc atgcaaatag gaaacagtca aaataatatc
     7261 attaaagcct tgatctctaa gcgaacacaa ttctcgttct aaaactggaa tgccatctat
     7321 aggaatcatt ggcttaggaa tatccggaaa caattccgaa attcggcttc ctcgtccgcc
     7381 cgccataatt actgttttca taatatgccc ttccctaaag tactttttac tataaaagtt
     7441 aattactctt cccaaacaaa gtccatatat ttttcatatt ctgctttgta ttcgtatttt
     7501 ccagtgtaca aattcaacca atttataaaa tcaaaattat agcagtgaag tgcatcttgg
     7561 ctatcatcaa tataatacgt accataaata gtattatttg aataacgacc tacatattta
     7621 tgccagtaca aatcaatttg atttttgtta atagtaataa catggttttt tacaaactcc
     7681 caatatgccc taatagagca ctcctcattg ccccccattc gtgaaatata gcttcgaaga
     7741 agctgaactt ctggagctaa attattttca gatatctccc ttcttgagac tcctctagac
     7801 acagctccct tttctctcac atcactagga atcgagaaga ggtttatcat atcatcaaca
     7861 tcaccaaaat acaggaagtc tgacaaacaa tacgggaaaa acatgtctcc atacggcatt
     7921 gatagtaaca gtaatcgctg attttgtatt aatttccaat catcttcgtt attaacagga
     7981 tactgttcaa gtaaactgca gaaaaacgcc attgcatttg gatggtatat tctttgatct
     8041 gttctagttt tacaaacata ctttgcacca agctgctttg ctctgactat tccaggcaaa
     8101 gtgtttccaa cttgataatt aatatttaag tgtccaggct tttcaggttt ctcactacaa
     8161 ataactataa ctccaagatc ctctatcctt ttcaatgcct taatatcttc gtccttccat
     8221 gtcgaaagaa taattaaagc atttggataa catttcttat agtaggccag agtattataa
     8281 gagaaatcat cctttaaaca tagtggcccc tgcattacaa ttgctacatc tttgcaacaa
     8341 ttaactaaac ccatcactgg aacatcagac atgtcctttg agcgcaattg aaacgctgca
     8401 taaacttcag aattttcttc tactgttgca caatcagcag tcaatttcca agatacgagt
     8461 ttacttatat tatgaccaaa catgttccta aacacatatg gtaaattttc gtacttcttc
     8521 aatatgttat ataaaatctc tttcttattc atgagatgca ctcctattaa tatttcctat
     8581 tctatgttag ccacacttct acattcttga tagatgtatt ctataaccgc taagcataca
     8641 ggaatagctg gagtaaatat cggataaaac cagtctatat taatccctgt tagcaagaca
     8701 tttaatgtaa ttccaaatgc taaatattga tagccagtca tacccacttt tgatgcaagt
     8761 aatgctgttt tgaacccttt tataataaac agaatatcaa atataagtat acctacacca
     8821 tattgagtaa ttgtatagaa aaatccaata tcagataggt gtcctctaac tcctcctggt
     8881 aatataaacg taaattcctc accagtaaga ataccagtac cgaacaaagg cgattgcaaa
     8941 aatttaggaa taaaaaacca aactgaagca aatcgagatt cagcagatcc tgcatattca
     9001 cctgtactgt ttgtgaaagt ttcaacaaat gttgagaaca tggtcgaatt aataaatatg
     9061 actacaagca acccagctaa aacccacatt gcaatttttc ttttcgaaga acctttctta
     9121 aaaaggatat agcaaccaag tacaataatt tgatagacaa ggacagatct agaaccatga
     9181 ataacagcag aatatgccag tgcgctagca atcagtaaat aatattttac ttttcttcta
     9241 gctacaactt gtcgctcaat catatacaaa gcaatcggta ttattataat tgtaaaacat
     9301 ggtggattaa ttcttaaaaa gcctccacga taccaatttt ccggggcaca ctcacgatat
     9361 atgttttcat agagaagtac tcctgaaaat ttctgaataa gtgaaataga tgttctaaga
     9421 atgtatgaaa gaaatgttac accacatatc gtatttagca ttgaatccaa attccacgct
     9481 tggttaatta aagtacagaa caatggatac gccaataata catagtataa actcatactt
     9541 tccctagatt taacccatat tgtcttatct gagtagatgt aagctgctat tataacaaca
     9601 caaatcagta aagtgcagaa atttaaatat ctattttttc taaatgctgg taatgaggct
     9661 attaacaaac atactattgc tagaatgact gtcacaagtc taacgttcat cgtttctccc
     9721 aaccagccgc ccaaaggctt caatatgctt gatgagataa tcattagaaa gaccattaga
     9781 aactgtatga ttttccattt actaatctgc atgttaatta ttattccttt ctaattgttt
     9841 tactactcat tcaaaatttg tttgtatgcc tcgtatgtga gttttgcaga tgccgcccag
     9901 gtatacttgc ggtttacaag ctcatatata tcatcctcta ttttgctttt ctcagctggg
     9961 ctaaggttca catactttac aattgtgtct gctaggctct tagaattcaa attttcgaaa
    10021 agtaacccta tctttccttc ctcggtttct tccataaaag caggtacatt actaacaata
    10081 gttggtaagc aataagtgta tgccataaga agcgctccac ttccatagat ttctttatat
    10141 ggaaatattg cggcatctgc atttctgaac atactgtcca tttcttcatc agaaattctc
    10201 tctggcttat atagaacaca atctgaaacc tttaaatctt caatcatttt tttatagtca
    10261 gtactatcct gtttaggatg ttgttgacct gctatggtaa aatgaacttt ctttcttaca
    10321 tccattggaa gttctgtgat tgcattaagc agtacatcaa ttcccttata tggacgaatt
    10381 tgtccaaaca agataaattc aaacttatct ttatcatacg ctctagatat atgtttaaca
    10441 tctccataga tagcatgtgg acaaacatat gactttgcat ttaattctgg gaattcagca
    10501 tataaatgct gttctgttac tcgattgtga acaatgaaac catcacaatt tgaatatata
    10561 ttaaagtgct cttggcgatc cttttcacga acctcatgtg gtaacacatt atgaactgtc
    10621 ataattaatt ttttatagtg tctcttacat aaaacgtaca atccgccttc atatttgaga
    10681 cttttcatca attgcaaatg aacaatatca taatcaccaa atcttatttc cttccaaatt
    10741 aagaacaagc ttttcagaaa aacaagtgcc gaaaacactt tatttgtact tttatgatac
    10801 aaaatatgtt tgctcttaat tttaggatct aaaggaggaa catcacgctt acacagcaat
    10861 gttaaatcaa catattgatt aagttcttta gaaagatcaa acgaatacca attctctggc
    10921 atttggcttt cacacatcaa taccttcata atactcacct tataaccaat caacagaaaa
    10981 ttctgctttc agttttcctt taattttacg ttttgctata aacatttcca gtatctctcg
    11041 cattttcgtc tgatattttg tcgttttacc ataaagcgag tgattgtccc ctgttcctaa
    11101 tacatatact gctgctttga atggaagagg ttttaatgga cgcccttgct cttcacatgc
    11161 tggaacaacg cccccatgtc gttttctaat gatccatgga ttatcatcac aatttgctgt
    11221 cataacttcc ggatatgcct caggcaggtc ttccactgca tattttacta tacacgcact
    11281 tcctgatgag aactttggta gaaccttcat ataatcgtct ccaacaaagt acacgtatcc
    11341 cgttttgaca taaaatccat tttcctgggg atgggaattc acatattccg ccaaatgaga
    11401 acttacaaga tcatctgcgt caaccatcat agcgaaaccg ccgcccaact ctcgcaaacg
    11461 cattgcgaga gcatgtgttt tataaccctt atcaatcatt ttttcgtctt gatttgtggg
    11521 aataggggca tccttttcgc taacttgaat aaattcaact ctgtcatcat attcatgcgt
    11581 gagtttagga atttcatggc aagcaacaat gattttgaaa tcaggatcag tctgattata
    11641 acacgaccat aatgttcggt taaataaggt actaaccatc tcccaattgt ttgctgcctt
    11701 cgcactcatt aaaggaataa caaaatacaa catacaatct ctccttttag taacgattca
    11761 aactacaata atcatttaca tcaatatctt ttttcaatac tctagccgga acgcctccta
    11821 ccgaacaatt aggttcaaca tcattaatga ccacagcatt agcccctact attacattgt
    11881 cccctattgt gatattacct aaaatttttg cgccagtagc gatatataca ttgtttccaa
    11941 ttgtaggcat accaggctta ttggatctac caccagtcag tacattcgtt ccgattataa
    12001 cgtgattacc tatttttgta tcttttccaa ttacacaacc tatgccaccg tataagaact
    12061 tacaattatc tccaatttct gtttgatatg aaattgagct attatgaagt acataaatta
    12121 gtgcctttac aatcttggca aaaaactcca ttttgtgtaa gtaaaaccat cgttctactt
    12181 tgtataattt atatgcattc atgttttatc tccccatctt tttagcaggt accccccaca
    12241 cttcgtaggg tggaatagac ctcaatacca ctgtatttgc agcaactaca gcaccttccc
    12301 caacgcataa ttctgtgtta gatttacaaa gaattttagc acccacacat aaaacagcgt
    12361 tcttttttac tcgaatgatg atacgttcat tactatctgc tcaaccacac gtcacattct
    12421 gatagacttt aacaccatct tcaaggattg tgtcagaatg aatcacagtg cctacagaat
    12481 tatgaacaaa ttcaacagag ttccctatct gtgcaccttt accaatacaa caaccaagaa
    12541 ttttggctat ttttctcgtg caattatcaa ctatgtttaa agcatatcga ttcctcaatg
    12601 ccattaattt cgttacttcc atatcattta tcaccttcca acatgctaag cataatttct
    12661 cccgactttg accatctaaa ttctgtagtt acacgctgat atgctgcatc tatgatatcg
    12721 ttggtaaatc gtccgtcttt taagaatgtc aaaatttcat cgtcagattt agccaacatt
    12781 ccatatctat tatccaaaat aatattctgt gggccaggtg cattaacagc aataatcccg
    12841 aggcgatagt acattgcctc tagcaaaacc ataccccaaa tttcagtata gtttagattt
    12901 acaaatacat ccgataagca atataactcc caaatatctt tgttaggaat acgctcaatt
    12961 atttttactc tattctgcag tccaagtaaa tttatctgct gcttcgtttg ctcgagtaaa
    13021 gcaccagttc ctaccatcag caaataatta tgctcatcaa gtttattaaa taaactaatc
    13081 atatctaacg gtcttttatc cttttcaaac cgtcctacat ataaaataac acgaacattg
    13141 cgaggaatat tccatttttc tctgagagta gtaaaatcta ttgcttcgta attcttatgt
    13201 aactgttcaa aatccacaca aacaggagca agtttcactt tatttactcc taattgtact
    13261 aatttttcag aaactcgatc atttttggca acacacccat ttttcttata aattttataa
    13321 tttcgatgcg ccaatatttc aataattgtc tttatatatt tattgccact ttgacttcgc
    13381 gttatcccat tataaggtat atattttatt ccatttttta cagtccatga gtatacatga
    13441 ggtactgata gttgaaggtc cgcaaattgt attagaacat ccgcattctt atcaaaattc
    13501 tttgttgata agaatccatt tgatcctaca taacgacact tgatatagtg aatcatcgcc
    13561 gtattgctta attgctctgt tccaacttcc tcatcacttt ttacactttt atatacaata
    13621 acttcgtggc ctaattcagc taaccctcga gctaatccta tttcctgaga attataggac
    13681 cccttcttac caaagttatt cgtcattgta actactataa gtattttcat ctatttttat
    13741 tgccccccta cttagattca atagtatagt agatatactt tatacctccc aagatatacc
    13801 gcctccatag tctacgaggt tcctttacca gtctaaataa ccactctaga ctagcttttt
    13861 ccatccattc aggagctttt tccaaagtgc ccgcaaaaaa gttaaagccg gcgcctacac
    13921 cgaacattac tgtgttatgg atcttcttct ggtgttccca catccacatt tcttgcttag
    13981 gcgcaccaat accaacccac agaaaatctg gatttaagtt gttgatttcc tcgcaaatct
    14041 tgctatcctc ttcttcattt aacggacgaa atggtgggga atacattcca acaattttga
    14101 ttcccgggta atctctttct aggtttgcac gaagcttatt taacacttcg ttatcttttc
    14161 caccatagaa ataatgtgtt tttccctgtc taacgccttc ttcaaaaacc attcccataa
    14221 tatctggtgc agcacatcgt tcacaggtaa atcctttgcg ccgtccaatt ttaacaatag
    14281 gcataccatc tattgcagcc attgtagcct ggctatacat ttcagcaatt ttgggatttt
    14341 cctttgccga aataatggcc ggcactccca cgagatcaac agtcgcactt accggagatg
    14401 ttggcatgga aaaaacttcc cttacaaact cgttctttgt agtagcacaa acacctacta
    14461 ttccacacac agtgaaatca cgttttcttt tatacatatt cttttccatc tcagtacatc
    14521 cttactcata tgttcttcct ccgcatcctc taattacacg gaggaagaac agcttatata
    14581 cttattaacc cttaatctgc ttttcaatcc aattgtagga ttcacgaaga ccctcttcca
    14641 aagaaacagt aggctcccaa tccaaaatct ctttcgcctt agaataatct gcgcaacgag
    14701 ccttatcacc ttcaggctta gaagtatcaa agaaaggctt gatgtctttg ccagaaattt
    14761 caatgatctt atatgcaatt tccttgatgg aagtacagtg agaagggcca atctgaatat
    14821 gaccatgacc ccaaccctta tccagggcga gcaccaatgc atttacgata tcattgacat
    14881 gaatgaaagc acgtccctgc tctccgctac cccacacatt aaaaggctct tcaggattat
    14941 tgattgcttt acgaatcaga gcaggaataa cctgactacg ttcgccaaaa tcagtaggtg
    15001 tgccataaac attatggagc atcaggatac agcacggaat tccggtttct ttttccaaat
    15061 accccatctc caactggccc atcagtttgc tccagccata agcagactca ggaagagcag
    15121 ggaacaactc ctcttcacgg agaggctcag gattcaaagt attctgtctg gtcagaggga
    15181 aggagcatac ggtaccaaca tagataacac ccttgatttt ctccttgcca gccttacggc
    15241 aacaatcaaa aacattagaa ttgatcagat tattgattcg gaacaattcg ccctggttct
    15301 taaacacata gtcaatgcca gccacaacat cagccagatg aactacatac tcagtcgtac
    15361 caataacctt tttagcctgc tcataatcag tcagatcagc attgaagaaa tgagtatcca
    15421 ggtcgatgac aggatgccca tcttcgtcgt tcaggtactc caactttcct ctccacagat
    15481 tatcagctac ataaacatcc cagcagcctt ccttcaccag tctcttaaca agattggagc
    15541 caatcatacc gcaaccaccg gtaaccataa ttgtcttttt catttaacat tcctccaaat
    15601 tttattcgtt tccaaagaat ttatcttcca gcatcaaaca ccaacaatga tatatcggca
    15661 agtgatactc ttgaatcatg tatgtttcaa cttcaggagc cttaacacaa acatctgcta
    15721 ccgtggcaag ttccccaccc tttgcgcccg tcaagccaat aacttttata ccgagagccc
    15781 tagcaacaac agttgcgctc ataatattct tgctatttcc ggacgtcgaa ataccaagga
    15841 atacgtcacc agatctacca aagccaaaca gctgctgtgc gaagacaccc aaaccatcga
    15901 catcattaat ataagcagta gacaatgctt cgtgtgcgac caaaggaatt gccgttaaac
    15961 cacactcgag atttttggct aattccggac ctcttacagg gtcaattgca actaacttat
    16021 cggcaaattc cttacttaca ggacgtggcg tcttaaaccg cttcatcaac tcgccagcaa
    16081 tatgttccga gtcagcggct gatcctccgt ttcctgccac aagaagttta ccaccattca
    16141 aatagcattc ctccataatt aggtatccat cgataatgtc ctgtttaatc gtctcaagtg
    16201 taggatatcg tttaatcaat aagtcaatat gtttattaag tttttccgct aacattgtta
    16261 ctccttatcc attctgtttt tcaatataag tttccggcgt gtagtgaata actctagttc
    16321 caccattttc aaattcaaac ggaatataca tcaaatcacg catagcccaa cgaactgcat
    16381 cctgtttctc aggttgtaca tagaaaacca agaaacctcc accacctgca ccgagcaact
    16441 ttccgcctaa agcacctgca gccataccct tttcatatag ttcatcaatg cttcctgtac
    16501 taattgctcc accagtacct tttttcaatc tccaagtaac atcaagctgt ctaccgaaat
    16561 catctaaatt tctgttctta tcagtaagaa ttgcctcagc ttcatctaca agctcataca
    16621 tctttttcag tcttactctc ttatcctctg tgccactgac gttgttagcc ttttgaacat
    16681 cagaagaaaa tctagtgaat ccggtaaaga acatcatcag attgttgtta agctgctttt
    16741 tacgttcagg cgaaataatg acaggcagca cctcataacc atccacattg aaattaattc
    16801 gattgaaccc accataagat gcggcaatct gatcctgcca tccaccggct tcattacaca
    16861 gaactctttc aagataaatg gcttcatcag caagtttctt cttgtcagca tacttaccct
    16921 ccagtgcata aaaagcattc aacataccaa ctgcaaaaga actggatgta cccagaccag
    16981 agcgagcagg taaatcagct tcgtatgtaa gccgaatttc atgcatatcg agcattttca
    17041 tcgcattacg aatcgcagga tgctcaatat cttcaatgct agttactctc tcagtacgag
    17101 aataagataa ctcagcgctg taatcaaaaa atctaggcag atgtctcaca ttcacataac
    17161 agtacttatc aaaagtagta gaaagaactg caccgccatt ctctttgaaa taatcctcca
    17221 tatccgttcc accgccaaaa aaagacatac gaaacggtgt ttttgtaata atcataaata
    17281 ctctctccta atcttagtct ctctggaaga tatcacgggt atatactttt tccttaatgt
    17341 catcaaggca agcatcgtag cgatttgcta taacagaatc acacattgcc ttaaactgtt
    17401 ccaaatcatt cacaacctta ctgccaaaga aagtctctcc atctttcaag gtcggctcat
    17461 aaatcacaac agttgcacct ttagctttta cacgcttcat aacgccctgg atagaactct
    17521 ggcggaagtt atcagaattg gatttcatgg tcaaacggta aacaccaatc acaacaggct
    17581 tttctttgcc agcatcatac tgatttgctt ctgcgtaatt gtaataacca gccatctgaa
    17641 gtacacgatc cgcaataaag tccttacgag tacggttaga ttcaacgatt gcctcgatca
    17701 gattttcagg aacatctgcg tagttggcca gaagctgctt ggtatccttc ggcaggcaat
    17761 agccaccgta accaaaggaa gggttgttgt aatgagtacc aatacgagga tcaaggcaaa
    17821 ctccattaat gatctgctga gtgttcaagc ctttcatctc tgcataagtg tccagctcat
    17881 tgaagtagct gacacgaaga gccagatatg tattggcaaa cagcttaaca gcttctgctt
    17941 cagtaaagcc catgaacaat gtgtccacat tctctttgat tgcgccttcc tgtagcagtg
    18001 tagcaaaagt gtgtgcatcc tcaaccaaac gctcatcatc catatcggta cccacaataa
    18061 tacgcgaagg atacagattg tcatacagtg ccttactttc acgcaggaac tcagggctga
    18121 aaataatatt cttgctacca gtctttacac gaacagaagc ggtgtatcca acaggaatgg
    18181 tggacttaat aaccataatg gcatcaggat ttacttccat gaccagccta ataacagcct
    18241 caacagcgga tgtgtcaaaa tgttgagtgc ggctattgta gttagtagga gccgcaataa
    18301 caacaaaatc cgcagactgg tatgctgcct ttgcatccaa tgttgcggtc agattcagtt
    18361 ctttctcagc caagtacttt tcaatataat catcctggat tggagattta cggttattaa
    18421 tcagttcaac cttctctgga atgatatcca ccgctgtaac cttatggtgc tgtgccaaca
    18481 gagtggcaat actcaaacca acataaccgg tgccggcgac tgcaatgtta tactgtttct
    18541 tcataatatt tcctctttcc accactgctg tggtcactac tttcttaaca aaatgctgtt
    18601 tgtgaacagt aacctgctat ttatataaaa cagcccgaaa gctgtgttca ttcatactta
    18661 aaacagccag ctcctacgcc ggcaaattca atttttcata aatcccctac ccgtttaggg
    18721 ttatattgca agtttgagtc atttttattg acctcgtttg gggttataat acattttcgc
    18781 attgaaatgt acctacattt tccactcaac cagtcaccaa aaagtttata aattcactta
    18841 ttaccctcta ttcttactcc aaaggtatgt ttaacatcgc tttattgacc tattttcacc
    18901 ccaaatggaa gtttgtttgg tacattattg gtctattccc accccaaact gtctattttg
    18961 agcgagtttt tgttttttat cattgcacat tttcaaggct caaattctaa gcggatttac
    19021 tggcagggag acattggtaa atacttgaac aatttcacgg ctttcatcat cacatcctac
    19081 gataataatt ctaattggat aaagattatc attaataatc tactttcacg taaaaattct
    19141 gaactaaata aaatctattg ataatatttt tttcttccac tttttgtata tcctacaggt
    19201 atagtggatt taattatccc caatgcctct gaagtaacag acatcactaa ttcaataaca
    19261 cattcactac catagtttgt aggaacaaaa atgacaacaa aatctgcttc cttatgtgat
    19321 gtttttccat ctgtccaaat tttattacca atgaaatcta gtttaaaatc cctcttagaa
    19381 actagttcac tctatatttt tattcagttt cattagttct gtttttttgt cttcagtcac
    19441 catatacata tatatcttaa ttatctatcc atttcatcct acgcattctt gcgtaaatac
    19501 aattcactct gttgagctga tataaatcat tggtggtaca aagataaaat gataactgtt
    19561 tctatacctc caaaaattcc agtaaatata tctatagata gtttcaaaaa aaattgtctt
    19621 agtttcataa tatttaagat agtggtacat actttataac aacgtacttt tccaaatatt
    19681 attttccgtt atgaacatcc aatatattac aaagtttaaa agtttagatg aactataatc
    19741 ttcatttctg cacagtggat aataaattct tatagataaa aaatagcctc ttctaaagtc
    19801 acaaatacct tactcccaca ttttaagtaa acactctgca gcattctctt tgttataaaa
    19861 tgatagatat tcctcaattt tatctcttat tatgttatta tcagttgata ccattccatt
    19921 aatgtttcag aataattaca atattttggg accggataac tcccttttgc tcgtaaccac
    19981 tcatatccgt taggattcac taaaagttta ccgtttattt ttcgattctt tttttgaacc
    20041 gtcccatgaa cataccgatt caacaagcta aattataaaa attggtgtgc tgtcattatt
    20101 ttttggaaaa tttattaatg gctatcaata tacttttgta tcatactaaa tagctcgtca
    20161 gttcctatat cggatatacc aatattaaag catttagatc attatattta agagtggtat
    20221 catcccaaaa tttcgaatat tttcttttat ataagaataa tgatactgaa ttgccccatt
    20281 cacctttctt tttttagatt ttctacaagt gattcaaacc ctccataatt acagttatta
    20341 cttttgaaac gataatatga acatgtgtaa tcttttttat taacaatcca tcattctatc
    20401 cctaactaat atgctccatt gggcttgaca ataacataaa acgtttttaa aatcaacctc
    20461 aagtcgtaca ttaaacttcg atgactaata tactctaaat ccaactcaac cattttatgg
    20521 aaactaacat tatttctatc actaacttgc cacaaacctg aacaaccagg ttttacatac
    20581 aagcgttgaa gatcatatct cgtgtactca gctacttccc tctccaaagg tggccgtgga
    20641 ccaattagac tcatatcgcc ttttaaaaca ttccatagct gtggcaattc atcaatgctt
    20701 ttggcacgga taattttacc tattttagtg acacggggat cttctttcat cttgaacatt
    20761 gcaccttcta tttcattttg atcaagtaat tcttccaatt tttcttcagc atctaaacac
    20821 atcgaacgga atttatacat tttgaatgtt tttccatttt taccaacacg tgtatggcaa
    20881 aaaaatatcg gacttcctgg ctcttctttt ctgattcgat aagctacata gaacatcaaa
    20941 ggagaagcta aaatcaaacc aataatgctt cctacaatat caatcattct tttaaaaaat
    21001 aaatagatat atcgtttttc aactttttct ttatccaacc aaacttgatt aggatgtact
    21061 tcactaatac gagataataa atcttcactt tccatacttt ccctctctcc tcatttcctt
    21121 tttatctacg aataaagaac taaaataaac caaacttctt cttttttacc tcttcataga
    21181 ctggataact gatttcatcc ccgttgatca gatcctttgc gacttgtttc atctgtacta
    21241 ctttttcctt accaaagtcc ttagcaatct gctcatagca ctcttttaag taaaaggtac
    21301 gcttagagac cccatgggca tcagaagcag ccatctgcac aagattatgt ttgaccatca
    21361 ttttggctgt tttctggatg tcttttccaa atacaccgac ataacttggt gcggtgagtt
    21421 gggccaagca tcccatatct aggaatggca gcatatgatt cgggtcttta cgaaaatgcg
    21481 cgttgcgttc tggatggacg atcactggtg tctttcctag ttgtaacaac tcaaaaaaga
    21541 gctgttctgc atataacggc acttccagtg tcggaaattc gattagaaga tatgtatcat
    21601 ctaaatctgt aaataaaatt tcatctcggt cgatgtcttc gatcagtgtt ccggtaatac
    21661 gtacttcttg tccttccaat aacgtcaaag gcaattgtct tttctctaat tctgcttgta
    21721 acgaagcgac tagagaaatg acttgtgatt tttcattgct gtattttcca ttattatgat
    21781 ggggtgtgca taaaatatgt gtgatccctt gttgaatcgc tttttcagcc atggcgatac
    21841 tggcatctat gttttctgct ccgtcatcga ttcctggcag gatatggcaa tgtagatcga
    21901 tcatttctct tgtctcctct ctttttattt cttaattccc gtagtaatag ccagcatctt
    21961 tgctgtgttc tgccccattg tatacaacac caaggactcg cgcttgtacc atatccagca
    22021 attcttttgc tttagtcaat gattctttcc gtgacatatt ttcacgtacg accaataagg
    22081 tgccatccgt tttggaagac atgatctgtg catctgttac ggcaactact ggcggcatgt
    22141 cgaagatcac tacatcaaat agttgtcttg cttctgctaa aatctgatcc attcttggcg
    22201 aacttagtag ttctgatgga tttggtggtt taggtccact tggcagaatc gacaaattct
    22261 cgactggtgt tcgttggatc tcatctgcta cacttcctga tgaactaaga acggtactta
    22321 atccgcttgc gttgttcaac ttgaacgttt tatagatgac gggcttacgt aagtctgcat
    22381 cgactagcag cacccgttga ccagatttgg caaaaacaac ggcaatgttt gctgcagtgg
    22441 tcgatttccc ttctccaggt cctgatgaag tcacaacaat cgttttaatt tgctgaccag
    22501 ctgcggaggc aaactggata ttcgtccgaa tcgtacgata ttgttcagcg attggtgaag
    22561 aggggtttgt gagtgtgacc aaactgactg catgagtttg ggctgctttt tgtttctgtg
    22621 ttcgtgccat ttttctttcc tcctagactc ttgagcggct tctgcgtgat ggcgctgttt
    22681 tatcgtttgt agcttttggt tgtatcggag ctggtccttt tttacggata ccagcattca
    22741 attctttcgc tgacatttct ggtacagtcc ctaagatcgg gaagcccaat gtatccgtca
    22801 catatttttc atcttttact gtccggtcga gtaattcaaa taagaaagct agacctacgc
    22861 ctaccatcat tcctaacact aagccaatca ctagattcaa tttattattt ggcgaaacag
    22921 gtgtcgtatt ggcaactgca cctgagatga tcgagatttt atcgacattc atcacgtctt
    22981 tggcgttctc ttggaatact tgtgacgttg tattagcgat ttgttgagcc gtcactgcat
    23041 ttgtgcttgt tgcttggatc gagaacattt gtgaattttg tgactgattg acggagatgg
    23101 catctttgat ttgtccagca gtcattttta cattgtcttc tgtttctaaa cgatctttga
    23161 cttcatttag tactagatca ctgacgatca tatccttata cgtattgatc atttgcaggt
    23221 tcgtattgac atcattgaca tttgcagtat ctgattgcgg cagtgtcacg atcaattggg
    23281 cttgtgagct gtattttggc gtcaagatga aaaacgtcac gatgcctgag atggccaagc
    23341 cagcaaacat tgagatgagg attgttatca cgtgtttgcg taatgtttca aaaatttctt
    23401 tcaagctgat tgtctcttcc attttttctc cactttccta tttattctct agattcattt
    23461 gatcttttaa ttcttttttc acacgatcaa gttcttgatc gctgactttt tggtatgaga
    23521 tattgtcttg catgaagcct tctccttgca gctgatcttg cttgatcgta ccaaatgcat
    23581 cccgataatc taaagcaatc tttttcattt catcaaagct catgtctgtt ttcatattcg
    23641 actctagagc attcaaaacg gattgatagt tgcttacacc gttcagactc aacacttttt
    23701 tcgctacacc ttctacgatc tttctttgac gttcttgtct gccgtagtca ccatttggat
    23761 cttcataacg catacgagaa taagacaatg cctgatcccc gttcaatgtg attttaccga
    23821 tcgtaaaatc atagccatct tgtgagaagg tgaggtcatt attgacttcg ataccaccaa
    23881 ctgcatcaac gagttctttt agacctttca tattgattga aacatagtga tcgattggga
    23941 tgtctacata tttttgtacg gtatccatcg ccatggcagc tccgccgaat gcgtaagcgt
    24001 ggttgatctt gtcttttgtg tcatgtccaa cgatgtcgac atacgtatca cgaggaatgc
    24061 tgacaatcgt tgtctgtttg tcttcaggac tgactgtggc aaccatcatc gtatctgatc
    24121 ttccttgatc gacccgacct aaatctcccg tatcaatccc catcaataga acagagaaag
    24181 attcttgttt gtccagatca actggttttg ttcgttctcc ttgggttcgt tccactgatt
    24241 cgtaagtttt ttcaatagaa tgtgagagat ctagatataa ttttgctcct actcctacga
    24301 ttgctaatac taatacgaca agaattgcta aaataattag aaatatcttt ttccctcttg
    24361 atcttcttct tcgttttgcc atagtttcct ccgtttgcta gccttgcttg aattctcgct
    24421 tattaatagc tcgtattgct atagcccatt tgctgagcga ctgtttctgc ttttgacgcg
    24481 tatgcggctc ttattttttc attccggatc tgttcgatga gactgagtgc ggtcaaatat
    24541 tgatcgtaag tagcagtagc tgttacttga ccgtctttca gcatcgtatc gaatagctga
    24601 tctagttgcg tgacttgcgc gatctgagta tcagcgaatc ctagatattg cataacaacc
    24661 gttttccaag gactatcttt aaaaaagctc atattttcac gtacacgagc gacatctgca
    24721 cttgtcacct tttctttgat gacgacatcg tctacagctt gctgccagtt tgatacattt
    24781 ttagtaaata aatcgttgac agctgtctgg atcttcagtt ttgattctgc atcctctaac
    24841 tgcgttaaga ctgctttctt ttcttcttgg atcgcagcag cttctttagg taattctgat
    24901 tccttgatgt cataatcatc tgccgaaagt ttgatagaag atagtttatg tgacaaattt
    24961 gaaactgttt cttctgttat ttcaggattt aggaaaattt tttcttttgt actgtacagc
    25021 ttatctactt cttttgataa agaggtcacg gtgtcttttt gattggtgat ggcagattct
    25081 gcgtaattga tccgttgatg atgttgccgc tgattattga aatggtatcc aaacaagcaa
    25141 atcacaatag cgcctgtgcc taccgccaca gtagccaata acttgacgaa cggcttttcc
    25201 atagattcac tcctaaatat tgatgataga taaataaaga tgtgattcat tcccatcaga
    25261 atgagcgctt tttattttaa aagcataatt aaactaatat attcatagaa atatttataa
    25321 acaggttttc cctatataat cgttttcttg actagggaaa ttcctaattt aaaagtaaat
    25381 aaaacagtaa caagatcatg attaatcgtt ttcattttta tttcctctct tttcatgagc
    25441 attttgaaaa ttcgaacaaa gaataaaata acaaaaatta ttaaaataga attaataaca
    25501 gctatttata tttataacaa aaa
//
LOCUS       DAYNVV010000038        24577 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.038, whole genome shotgun sequence.
ACCESSION   DAYNVV010000038 DAYNVV010000000
VERSION     DAYNVV010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24577
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.038"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(152..550)
                     /locus_tag="ACGXWR_001769"
     CDS             complement(152..550)
                     /locus_tag="ACGXWR_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HFK0803326.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(547..1320)
                     /locus_tag="ACGXWR_001770"
     CDS             complement(547..1320)
                     /locus_tag="ACGXWR_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFK0803327.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1317..2000)
                     /locus_tag="ACGXWR_001771"
     CDS             complement(1317..2000)
                     /locus_tag="ACGXWR_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFK0803328.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2167..3054)
                     /locus_tag="ACGXWR_001772"
     CDS             complement(2167..3054)
                     /locus_tag="ACGXWR_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0803329.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3051..3920)
                     /locus_tag="ACGXWR_001773"
     CDS             complement(3051..3920)
                     /locus_tag="ACGXWR_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0803330.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4057..5343)
                     /locus_tag="ACGXWR_001774"
     CDS             complement(4057..5343)
                     /locus_tag="ACGXWR_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFK0803331.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5616..6194
                     /locus_tag="ACGXWR_001775"
     CDS             5616..6194
                     /locus_tag="ACGXWR_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFK0803332.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6194..7123
                     /locus_tag="ACGXWR_001776"
     CDS             6194..7123
                     /locus_tag="ACGXWR_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0803333.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7120..8856
                     /locus_tag="ACGXWR_001777"
     CDS             7120..8856
                     /locus_tag="ACGXWR_001777"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFK0803334.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(8919..9755)
                     /gene="pheA"
                     /locus_tag="ACGXWR_001778"
     CDS             complement(8919..9755)
                     /gene="pheA"
                     /locus_tag="ACGXWR_001778"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HFK0803335.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(9752..10261)
                     /locus_tag="ACGXWR_001779"
     CDS             complement(9752..10261)
                     /locus_tag="ACGXWR_001779"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HFK0803336.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10254..11549)
                     /gene="aroA"
                     /locus_tag="ACGXWR_001780"
     CDS             complement(10254..11549)
                     /gene="aroA"
                     /locus_tag="ACGXWR_001780"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFK0803337.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11562..12653)
                     /locus_tag="ACGXWR_001781"
     CDS             complement(11562..12653)
                     /locus_tag="ACGXWR_001781"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HFK0803338.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(12670..13836)
                     /gene="aroC"
                     /locus_tag="ACGXWR_001782"
     CDS             complement(12670..13836)
                     /gene="aroC"
                     /locus_tag="ACGXWR_001782"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HFK0803339.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(13838..14902)
                     /gene="aroB"
                     /locus_tag="ACGXWR_001783"
     CDS             complement(13838..14902)
                     /gene="aroB"
                     /locus_tag="ACGXWR_001783"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HFK0803340.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(14935..15957)
                     /gene="aroF"
                     /locus_tag="ACGXWR_001784"
     CDS             complement(14935..15957)
                     /gene="aroF"
                     /locus_tag="ACGXWR_001784"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HFK0803341.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(16616..17590)
                     /locus_tag="ACGXWR_001785"
     CDS             complement(16616..17590)
                     /locus_tag="ACGXWR_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HFK0803342.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(17571..19454)
                     /locus_tag="ACGXWR_001786"
     CDS             complement(17571..19454)
                     /locus_tag="ACGXWR_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HFK0803343.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(19472..21697)
                     /locus_tag="ACGXWR_001787"
     CDS             complement(19472..21697)
                     /locus_tag="ACGXWR_001787"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFK0803344.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            21812..22846
                     /locus_tag="ACGXWR_001788"
     CDS             21812..22846
                     /locus_tag="ACGXWR_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFK0803345.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(22913..23926)
                     /locus_tag="ACGXWR_001789"
     CDS             complement(22913..23926)
                     /locus_tag="ACGXWR_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFK0803346.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(24004..24192)
                     /locus_tag="ACGXWR_001790"
     CDS             complement(24004..24192)
                     /locus_tag="ACGXWR_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HFK0803347.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         7063 a         5341 c         4397 g         7776 t
ORIGIN      
        1 gcatattttg aaaagaaagt ctgatgctta gagtagaatt tcataaaaat ttactatttc
       61 ataagtattc acgagaaaaa tacaaacaaa aaagcggaaa taacgctcat ccgccttctt
      121 gtttgtgttt atttcctctt caaacgcttg tctatgattc agacttttct ctatcgttat
      181 tttcatctaa aagttcttgc attccgataa tttctcgata ttgatgaatc ttagtgatac
      241 caatgacttt gtctacatca atactaaaac aaataccatt acctggaata tcgatgttga
      301 tgccttgacc aatcgcatcc attactttat tcgtcaaact atcgggtact aatgtcaaca
      361 caatatcttt ttctggcgaa atgtccaaac ctaaaaattt ccctgaatca tgtacaccag
      421 aacctcttcc atgtaagatc gttccgcctg ctgcacctgc ttcttttgaa aagtcgataa
      481 catcttcgcc cattcctccg tcaacgatcg tcacaatcat gtgaagattc aatgctacaa
      541 gatctttcat ttgctttccc ccaatttttg caatctttct ttttcgattc tgtctttttc
      601 atcttttcgt ttataaatat atcctagtac taaagtggat aatattggtg tcaatgcaat
      661 cattgcaacc acaccaaacc cgtcaatgat cggatctctt ccttcaattt gtgcagcgat
      721 tgccacgctc attgataaaa taaatgtcga acacatcggg cccgttgcta ctccaccgtt
      781 atcaaaagcc attgctaaaa agatcttgtc cacttttcgt cctaaaataa atgctagccc
      841 gtatcctggg atcaagaaat aataaagaga gaatccgacg agcaaacgcc acatagacaa
      901 tcctactgct gcgccgatcc caattgaaat taccatcagc atgattttcg atcggattct
      961 cccctcgctc aattcttcaa cctgtttgat cattacatga atcgccggct cagcaaaccc
     1021 tactaagaac cccattaaaa agccaagggg aaccagtata taattgtaag gcaatcccgc
     1081 aatagcactg cctaaatgct gtcctaccgg tacataagcc atattgactc cgtgcaggaa
     1141 aaggatcaac ccaatagtcg ttatcaagaa acctttcata atgtcaaaga aacgcttttt
     1201 gcgcatacga aaactaatga tattcattaa aacaaatagg attacgatag gtgccactgc
     1261 caaaatgact tccatggtaa cgatttcgat tccatctatc acttgctgcc agaaactcat
     1321 tggaagatca cccccaaaat catcacggca agaatcggcc ctaacgaagc aataccgacc
     1381 attccaaaac tgtcattttc atttttcttt tgtttgatca tactagtcat ccctccggca
     1441 agggccaaga taaatggaac agttactgga ccagtagtca ctccccccga atcaaaagca
     1501 atcggcataa attcggaact ggtgaaaaat gaggcgatca aaacgcctat gtagcctata
     1561 gccatcaatt gataatagga tagcttgaat acgacccgaa gcagcgcaaa ggctagaaat
     1621 actccagtgc cgacgctgac gatcccaatc agcaacactc tgccaatctc tccgtcagat
     1681 atatcatata cttgttgtcc caaaacttgc acggaaggtt cagcaatcgt gatcacgatc
     1741 ccgatagcaa atcccaaact gaccaaaacg gtcaaacttt tctttttgat catatatttc
     1801 cctactagat ctccgacttc catcatagaa taatctgctc caaacaaaaa gagcgtcatt
     1861 ccgatcatca tgattgccgc accaaccaga aatgaagcga ggtcttctcc ttctaacggt
     1921 gcaaaaacaa acgttaaaat gacaatcagg acagtcatcg gcaatatagc agcaatcact
     1981 tctttaaaat tttttagcat gtatcctcct cctttactct ttaagtttac cttaaaatga
     2041 aagagttttc gagcacaaac ttaaaacgtt atcatttaat ttttctcaac ataaaataac
     2101 acacgtccca aaagtatctt tttacttgga aaaatgactt tgaaggaacg cgcttattgt
     2161 gtttttttat tttacagagc cgatcattcc ttgaacgaat tgcttttgca aaacaaaaaa
     2221 tacgatggca gttggtaaag tagcgatgac taatccagcc atgatcattc catagtctgg
     2281 tgtataggaa gcacccatag cagataaaac aagcggaacc gtccgtttat caggagattg
     2341 caaagctact aagggccata aataattgtt ccagctactc atgaatgtga tgattgcagc
     2401 cgcggcatag gtatttttag ccgtcggcat atacactcta aaaaaaatac ttagttcttt
     2461 tagaccgtct aatcgagcgg cttctactag atcttttgga aaagatttaa cattttgtcg
     2521 aaagaagaag atcaaaaaag cagtgctaac agatggcagg atgacaacca agaaactgtt
     2581 gattcccaaa accgttccgt tcaattgtga aaacattcga tataaaggga tcatcaatgc
     2641 cgcaaaagga accatcatcg atagcagtag aatattgaaa attaggtctt ttcgtttact
     2701 ttgataaatc tcaaatccat atcctgccat tgacgaaatc agcaatgcaa acacagtggt
     2761 caccaaagcg atcatcgctg aattccaaag ggaacgagta aaattcagct cattggaaaa
     2821 caaattttga aaattgatga tcaagttact gccaatcttt atttttcccg atgtgatatc
     2881 cacgggtgta ttcgtcattc ccaaaaccat ccagacaaaa gggaaaatgg aaataaatga
     2941 taggatgctt aatgctgtat actttaatac tgacccaatt gtcgaacgaa gttctaatgc
     3001 ttgttttttg acgttggggc gttcgattgt ttctttttct accatatttt tcatcgactt
     3061 tctcctccta ctttcgtttg gattatcgac aatatcacaa taaaggaaac aataacaaag
     3121 gaaactgctg ccgcatatcc aaaattaggc gtgaatttat aactcaaatt atagatgtat
     3181 tgagataggg tggtcgttgc atttgctggt cccccgccag taatattttg tacttcatca
     3241 aaaagctgca atgtcccgat cgtcgaagta atggaagtaa acaaaatgat tggttttaaa
     3301 tttgggatcg tcactttgat aaactgctgc catttagaag caccgtcaat agatgctgct
     3361 tcataaatct ccgaatcaat attttgcatg cctgaaagga aaaaaatcat attgtatcca
     3421 gtccaacgcc aagtgatcga aagaatgatc agaactctcg cccaaattgg atgagtcaac
     3481 cagccaatcg gtgtgtcaat cataccaatg cccaacaaca agttgtttac aaggccagat
     3541 tgagaaaata gacttttcat gatcagagaa taactgacca tcgaagtgat acatggaaga
     3601 aagatagcgg ttcgaaacaa ccctttatat ttcaactttt tatcatttaa aaggttggaa
     3661 ataaaaagtg ctagaaacaa catgatcggt acttgtacaa gtaaatacag gaatgtatta
     3721 aaaaaagctt ttttaaaagt tgcatctgtc aacatccgct gataattacc taacccgtta
     3781 aatgtcatat tgacaggggg accactttga aaagacgtga tcaaagccaa aaccatcgga
     3841 ataaaaacca tgattgatat caaaatgact ggcaagatta aaaaagcatg cccgtttttg
     3901 aataaatctt tctgcttcat tcttttccct ccaattctat cattgattat ctacatgaaa
     3961 agacaagaaa gacaatatct gtaaggcaga cgtgatcttt tttgtctttt cgtttgtctg
     4021 atgaaaaagc gaagaaattc acttttttac caccgatcaa ttagccaatt gtgcttctac
     4081 ttgtttttgt gtatctgcta gtaccttgtc tgtctcttct ccattgatga ttcgatgaag
     4141 agcttcagct acgactgctt caattgcata ggtctcatgt ccgtaattca cttctggtat
     4201 ttcagatgtc catgttgaaa aatcgtcaaa gatcttttga ccactgtaaa attcagaagc
     4261 ttcttgataa gcttcttgtt cattcgcgct aagcatcgta gatactagtc cgatttcttt
     4321 cgcaagagtg cccatcagtt cttcattcga agcaaacgtt gcttctagga aatctttcgc
     4381 tgaatcttct ccagctactc ctttgatcac ataccagcca gcgccgccaa ggttagaagc
     4441 ttgcgctttt tgcagatttt ctggaagtgc aggtattggt gcaatcttcc attttccaga
     4501 ttggttttct gctccttgga tcgttgaaga ataccaagcg ccagttgggc tagaagctac
     4561 tgctcctgat tgtatcgcag ttactccagc attccagtca gaggtttgtt cgactagatc
     4621 ttctttcaaa agagtggcaa acaattcaag accatacttt aaagatgcat tgtcttggat
     4681 cgtgactgtc tccccatctt cagatgtata ccattctcct gcctgttgca taatcatcct
     4741 tactcgacca aggtcagaag gattgacttc agcgattttc tttcccgtct tttctttgac
     4801 atctcgcgct acttgaatat actcgtccca cttcagattc tccatatcct cttctgtata
     4861 acctgcttct gccatcagat ccgtacgata gaagtttgct gttacgcccg aatcgaaagg
     4921 aacaccgtat attttatctc ctactttgtt taccgcaaat ttatacggtg caaaatgatc
     4981 ttcctttaca atagcagaca aattagcgaa tgcatctgga taagaagtca aatagccttg
     5041 tatcctataa tcttcaatca agacgatatt gggcaatcct tctgtattcc cgctcgctaa
     5101 agcggtgttc agtttctgaa cgatatcatc ctgagacatc gtaacaactt ctatctctgt
     5161 ttcttcgttc tcataaactt tttttgcttc attcactgct ttgatattga atgtctcatc
     5221 ccacgcccag acagtgactt tttcttcttt gtctgctgta ctactagcac ttccgcatcc
     5281 tgttaagaaa cctgatgctg ccgctaaaca aacgactcca gcaattaact ttctgatgtt
     5341 catttttatc cgctcctttt ccatccatta gttgtttacg tttgctacat tcatcatacc
     5401 aaaatttgaa aacggtttct ttattattca gatacttcaa aaatttctcc taaaataata
     5461 aaaaaataca aatcaactat gacaaaagga ataatcttag catctagacc aaagatcgaa
     5521 atggtgaggt ttctttaaaa taaaaatatc cttgcatttt ctcctagaaa taagtatttt
     5581 taaattacaa gactattctt aaggcgggta aaaaaatgcc aatacgcgta attcttatcg
     5641 atgatgaaca gacgatttta gatggaatga aacagttgat caattggtct gagcacgggt
     5701 ttcaattaat agggactttt tccagtccgc tgaaagcgct tgatttttct ttggtacatg
     5761 caatcgatat cgtggtcaca gatgtaatga tgcctgaatt aaatggaatc gaattatcgc
     5821 ggctattaaa acagcaacaa cctgaaacac agatccttat cctctctagc tatgatgaat
     5881 ttgatatggt taaagattct tttaaagaag gcgtcgctga ttatctttta aagcctcgat
     5941 tgagtcctga tttttttcta aattccttaa ctgccgtttc acaaaaaatc aaaaaaaagc
     6001 ccaacaaaag cccaatcacc aatcgttatg agcagatctg cgagaatctt tcacagcaga
     6061 ttgctggaca aactcgtcca ttgcttgacc ctcttctttt tgaacacacc ttgtttttct
     6121 gttatatacc gaaaaacggc cattcagttc aaaacaaggc tctaaacaaa aacagtcgat
     6181 cacccattca ttgatggata gcgacgattc gtttactatt tatcctgttt ctaccttttc
     6241 ggaagaatcc ggctatgtaa tcaatactga ttccaaagat acacttagga agtttgttca
     6301 aaagtttcgt caagaagttt ttccaggtga tttttttgtt gtttctgatt cttttgcaat
     6361 ccaagatatc aatgaaatat tccaagagat cagaaattgc accaaaggac aacgtttcta
     6421 tcataaggga aagaaccttg cttatcagca tgaacttctt ccgttattaa ccaaccacga
     6481 gcagcaagca agtagttatt taacaaaaat cgttcataaa gactacgctt tagctgtcaa
     6541 agaacttgag aatttcttca cgacgatatt ggaacagcct attgatccag cttatttgaa
     6601 acatgaggca atcaatcgtt tctatgcatt actcaacgct ttggctgacg agcatgttgg
     6661 gaatgaagaa ctttctttgc tcaagatcgc ccttccttct ttattagccg atgctgagta
     6721 tttcgaagat ttttctattc ttgtcaaaga aacacttgag aaactcaccc acttttctgc
     6781 aaatgcaaaa aaagacaatt tcgatatctt gactttgatc tacgagttcg tccaggaaaa
     6841 ttatgagaaa gaaatcaatt tacaactttt atccgaaaaa tatcattttt catatagcta
     6901 tctctcagcc atctttactg aaaaatttgg tatcaacttt tcaaaatatc taaaaaaagt
     6961 ccgtatcagt aaagccaagc tctttttgac ggaaacacgg cttactttga cggaaatctg
     7021 tgagaaagtc ggctataccg aactgggtta tttctccaga gtttttaaag aagagacagg
     7081 aatgacacct tctcaatacc gtaaaggaac ttttgtaaaa tgagaaaaaa aatcaaagag
     7141 catgaactct ttgccaaact tctgttcatt ttgttcatcg gtctttttct gcaagccatc
     7201 gtcatttctt tgtttattta tcatcgatca agggatgcct atatccagct gttcaatcaa
     7261 tcgaatgatg tggtactaaa aaagattcaa tctgaatttg aaagtttgaa tgatacaatc
     7321 gagaatacat tagccgcttt tgattctaat ccagctgtca aaagctattt ttccaatgat
     7381 ccagcccaac atatggaaca gcttcagcaa ctaagaacaa tccaaaaaat gaatgactct
     7441 ctttcaaaaa tccatccaat gatcgattac gatgtattga tctttggaga aaatggaaga
     7501 acttttgtcg gaaacgacat gctcactgcc gtatctgccg attctttttt tcaatctgcg
     7561 attgctcaga gagtgaatga acgtgctgct gatacacaaa tgctttttgc acaccacgga
     7621 ttgactcttc gcgataagaa agcacccagc gtcttctttg tcaaaaaact gaaaaataca
     7681 ttgaatcacg tttacggata tgctgtttta tcgatctcat ccaagcaact agcgaatctt
     7741 tttcaatctg tagtaaatcc tgagatatcg aagatctcct tcatgaacga agaacagacg
     7801 atcatcgcat caaatgaaga aaatacaatt gggagccgat caatgatttt caaaaaacta
     7861 acagtaggtg aaacaacgat ttcaaatgga cagcagttga cccgtcttcc tctgtaccgc
     7921 caggattgta cattactcag tcaagtcgat cttcattctt tatctaacca aatgggcgtg
     7981 atttttccga ttattttgta taatatcgtg acacttgctt ttgctggctc attggtattt
     8041 atgtatttgg atcgacacac aaaatcgatc taccgcttga ttgattcgct aaaacggcta
     8101 gaggaagatg gcttaaaagc tactgttcct gtacaaggaa gccatgaagt ccaattgcta
     8161 gggaatacga tcaatcaatt gctaagtaat gctcagcatc attatgaaca gacgatccaa
     8221 gacgaaaaga agaaacgttc gcttgaaatc caaactatgc aagcacagat acagccccat
     8281 tttatttata atacgctgac tagcttgaaa tttttgattt ggcagaaaaa aacagatgaa
     8341 gcagttcaag gaatcgacag tttcattact ttactaagaa gtacgattgg gaaaaaagaa
     8401 gaagtgattc cagtcaagga agaaatcaaa agcgtacaaa gttacatcga tcttttgagt
     8461 atgcgatatg gcgaaagaat ctcggctaaa ataatgattc ctgatgaact gcagtcatta
     8521 tctatgccga atatgatcct tcaaccaatt atcgaaaacg cctatcttca tgcttttcac
     8581 aataaaacgc aaggattcat cacggtgtac ggcaaaacaa aaaatcagct tcttttattc
     8641 gaagtgattg ataacggcga tggcttcgat actgaaaata ccaaacaaaa aaatgatcat
     8701 ttttcaggaa tcggcatcag ccatgtagat gagcggatac gcctaatgta tggcgatgca
     8761 tatggcttaa cgatccaatc agtgattggg acaggaacga ctgtaacgat ttgtctaccg
     8821 cttcttccta aaaatcaatc agaatatcaa aaataaagaa tagccaagcg ctgatttttt
     8881 tattttaagt taaataaatc aatcagtatt cttgactttc atctacgcgt ctcttctact
     8941 gtcagcactg gataacagcc caatatttga ctttctcctc cgagcatctt gatttcttgg
     9001 agcgcattct ctactaatgt cattggacgg tccaacaaca aatcgatcac gaaaaaatat
     9061 tctcccaagc tagttttcaa tggtcgggat tcaatcttac ttaagttgat ttcccgccag
     9121 ccaaaagctg ccagcatttt atgaagcatc cctggccgat tagcaggtag tgtcaagatg
     9181 acactcattt ttactggagc tgactgctgg ctggtcatct ttcggtcacc gacgatccaa
     9241 aaacgtgtct ggttcaactc attatcttgg atattctcag ctaagatctc caatccaaca
     9301 tgctgtgctg tttctaatga agcaatcgct gctgcgtctt ctttcggatg ttctgctaca
     9361 tacattgctg cagcagttgt tgattctgtt gctactaaag gaacattagg ataatgcgtt
     9421 tctaaaaact gttgtgattg tgctagtgct tgtggatgtg aaaggatttt tgtaatcttt
     9481 gttgctggat tgcctaaaag ctgctgcttg ataggaagaa cgatttcact tttaacttcg
     9541 acttctggat gtttggaaag aagatcgatt gtgtgatgaa cagctccttc caatgaattc
     9601 tctacaggaa cgacagccag atcgacttgt ttgcgaaaca aagcgcgcaa acaaacaggg
     9661 atggaagcat acgcagtcaa ttgttctgta ggaaatagct gacaagccgc ctgataagtg
     9721 aatgaacttt ctggccctag atagctgacg ttcatatgct tttgatcctt tctataatgg
     9781 tatcgatgat cttttctggt gtttgattgg tcgtgttgat tcgatgtgtc gcactttctt
     9841 cataccaaga aagtcgttgt gccaataatg cttttatttc ttctcttgtt tttccaagag
     9901 ctaaaggtcg aatagacgtt tcatcttgtt ggatacgatc aactagacag tccgcttctg
     9961 cctctaagta aagaacaatc ggctgtgttt ttaaaaaacg ccgattttct gcactttgga
    10021 caatccctcc accagtcgcg ataattttgt cttcatttga cagctttctt aaaatatctg
    10081 actccacttt tcgaaagctt ttttcaccgt aatagtgaaa atattcggca atcgacaatt
    10141 ggatatgttc ctcaatcttt gtatctaaat ctacatactc tttttgtaaa cattgagcta
    10201 accctttacc gattgttgtt tttccagcgc ccatgaaacc aatcagcaaa atgctagcca
    10261 tgagcttctc ctcctgacac aagttctgct aaatcgtcaa aaaatgccgg ataagagatt
    10321 gaaacagctt cagctccttc tagttcgcaa ggtccatcag ctatcaaagc agctacttgc
    10381 agcatcatac cgattcgatg atcgcctctg ctggacactt ttgcgccatg cagaggtgtc
    10441 ggcccatgga tgatcagacc gtctgctgtc gcttttatct ttgctcccat tttctgtaat
    10501 tcttctgcca ccgcatcaat tctgttggtt tcttttactt ttaattcttc tgcgtctttg
    10561 atgatcgtga ttccttctgc ttgagtagcc actaaagcta gaatgggcaa ttcatcaatc
    10621 agacgcggaa tgatttctcc accaatcgtt gctttcttca aatgactcgt cttgacactt
    10681 aaatcagccg attggttctg ttcattgtga ttcgtctggg taatcgctgc gcccatctcc
    10741 tccaacacat ctaagatacc agttcttgtt ggattgaccc cgacattttt taacaacagt
    10801 tggctttccg gaacaagaag tcctgctgct agaaagaaag cagctgatga aatatcacct
    10861 ggaacagtta tctgttgacc agttaatttt tgcggtccgg tcactatgat cgttttatct
    10921 tccactgtga tccttccgcc aaattgacga atcatttctt ccgtatggtt acgggaacgt
    10981 tctttttcaa cgattacgga tgtgccttct gcttgtaatg ccgcaaacag caaagcagat
    11041 ttgacttgcg cactggctac aggcatattg tatcggatag gtgataaaga gcgggttcct
    11101 gtcacagtga ttggtagata ctggtcattt tcttctcctt gcaagtcagc gcccatctcg
    11161 cgtaaaggtt ccatcactcg ccccattgga cgtttagaca acgaagcatc cccgaacaga
    11221 gtagtcgtaa aaggctgtcc agccaaaata cccatcaata aacgtatggt cgtaccggag
    11281 tttcccatgt caattgattc ggttggttgg acaaatgagt ggctaccgcg accatgaatc
    11341 ttgatcacct cttcctcttc ttcgatctcg acacctaatt gttggaaggc atgtaaagta
    11401 ctcagacaat cttctgcgcg caaaaaattt tgtatagtcg tcgttccttc agcaattgct
    11461 ccaaacatga tgctgcgatg ggaaattgat ttatctgctg gtatcctaac agtccctctt
    11521 aatccatgta tttgttgtaa taattgcatt tatccagcct cctatttgat ccagcaatga
    11581 taactggtat tagacataat gattcttttt gcttgtaaca aatcctgttg gtttttaaaa
    11641 ctgatttgca gtattcctaa aatatcttcc ctggtctctt ggatcttcaa attaatcaaa
    11701 gaaactcccg cttttccgat cagtccagtt acttctgcaa taacgccagg ttcatctggc
    11761 acatcgataa ataaatcaaa aaaggcagga atcgcgcctt gcttatggac aggcaactgg
    11821 tctcgacttt cttttgcccg attgaaaaaa gaaaagattt ccgattggtt ctcagtcatg
    11881 atccattctg ctatttgtgt catttcttgt tgccaatctg ccaatcgttc caataatatc
    11941 tgcttattgc tcaacaaaat atctgtccac atgacaggat ctgaggaagc gatcctagtg
    12001 atatctcgaa agcctcctgc tgccagttgt ttggctcgcg gatactcttg attgaattgt
    12061 tctgcctgat tgactaagcc agctgccaga atatgtggaa aatgacttag cattcctgtt
    12121 atacggtcat gttctcttgc tgtaagagtt acatattttg ctttggttcc gcaaaatagt
    12181 tcttgcagtt tttcaacatc ttttttcgtc ttttccaaag gtgtaaagat gtaataggca
    12241 ttttcaaata gtttagcatc tgctgcctgt atacctgatt tatgagaacc agccattgga
    12301 tgtccaccga caaaccgaag atttttctgc tcagcggatg tcacgacttg ctgcttcgta
    12361 ctgctgacat ccgtaatgat gacgtgatca gacaagttga ttctttcaag gacatcaaga
    12421 taagctaagg ttgtacggac gggaacggct aataagataa cgtctgcttg ttctgcacct
    12481 gtttcaaaat cacttgcaac gtaatcaacg atctgctgtt ctactgcttg ctcacgggtt
    12541 tttgactgac tatcccaacc aactactatc agttctggat tggtctgacg aatacaaagt
    12601 gccatagaag caccaatcag tccaagcccc acgataaaaa catgttgtgc catcttattt
    12661 gccccctttt tagtaatgtt tcaagtagtc acggtactcc ttcactgcag ctttcaactc
    12721 aacaagcgaa tcacttggga attttgacaa tagctctgtc gctaccacag tggctacaac
    12781 attttccgca acgacgctag ctgcaggaac tgctgtacta tccgaacgtt ctacacttgc
    12841 tttgtaaggt tcttttgtat cgatatcaac actttgaagt ggcttgtaca atgtaggaat
    12901 gggtttcatg accccgcgaa tgacaagtgg ttcgccattg gtcattccgc cttcgaagcc
    12961 gcctagatta ttggtacgtc ggaaatagcc tctttcttct tcccatagga tctcatccat
    13021 cacttctgag cctggtaatg aaccagaagt gaatccgacc ccaaattcta cgcctttaaa
    13081 ggcattgata ctaaccacag cttgtgcgat tttggcatct agcttcgtgt cccattgtac
    13141 gtagcttcct aatccagctg gaacgcctcc aacgagcact tctacaattc ctccgatcgt
    13201 atctccattt ttctttgtct gatcgatcaa atcttttatt ctttgctcaa ctgctggatc
    13261 aacaactcgt acttctgacg cttcagaaat ttctttgatt tcttgaatcg agatatttcc
    13321 aggtatttct gcttggattc caccaagaca aatcacgtgt cctgctacga tgatgtcaag
    13381 ttcttccaga attttcttgg caattgcgcc gattgctaca cgcatggtcg tctctcttgc
    13441 agaggaccgt tcaagcacat tccgaagatc tcgatgatgg tatttcatac cgcctaccaa
    13501 atccgcgtgt cctggacgcg gacgtgcaac tcgccgcagt gattggtctt tttcaggcac
    13561 ttctgctaca gacatgacag ttgtccaatt tttccaatct ttattttcta ccactaaagt
    13621 gacaggtgaa ccaattgttt tgccgtgacg gatgccagac gtgatccgaa cacgatcttt
    13681 ttcgatcttc atccttcctc ctctgccgta accagcttgt ctgcgagcga gttcgtgatt
    13741 gatttcttct tctgacagag gtaatcctgc tggtagtcct tcaataatgg ctgttaattc
    13801 tggtccatgg gattctcccg cagtcatata acgcatctta cagtcctcct aagtaatctt
    13861 tgaatgtctc tgtgggaaca ggaacgattt ttgcttgccc aatcttttct agcaagatga
    13921 tattcaattg gcttcctctt gctttcttat catgggttat cgcgtggaat aattcatctg
    13981 gatgacttag atcgtacgta atcggcagat ggaatttttg aagtatcctt tctaaagcag
    14041 ctgtcgatcc agttggagac aagccgattt tttctgcatg agaagtgatg gctaccattc
    14101 caatagctac tccttctcca tgactgacta ccccatatcc tgctgtattt tcaattgcat
    14161 ggccaattgt atgaccaaaa tttaaaataa gtcgatttcc ttggtcaaag acatcttctt
    14221 ccactacttt tcgtttgatt tccaacgtag cagtaatgat tggaacagca tgttccagaa
    14281 gatctttttc gtctttcagc tcgttcagct gtttccaaag cgttgcatct gctatagctg
    14341 ctgatttgat gatttcagcg attccttctc gtaaacgacg taccggcaaa gtttttagaa
    14401 cctcaggatc aatcaataca ccagctggct ggctaaatgt tccgacaagg tttttcgctt
    14461 tgtttgtatt gactgctgtc ttcccgccaa tactagaatc tacttgtgca agtagcgtag
    14521 tcggaatttg aacgaaatgg atcccacgca tgaacgtcga ggccacgaat gctgctagat
    14581 cacccaccat tcctccacca agtgcaagta tcccatcgct gcgggtaaaa tcattatctg
    14641 ctaaaaaatc gtataactca gctgcttgtt ctaaagattt actggtctca cccgccggta
    14701 cgattgaaag gactggttca aaattagctt gtctcaattg gaacatgatt ttttctgcat
    14761 atagtggagc aacgtttgta tcagtgatca cagctacttt ttgaggtctc caaatcgttt
    14821 gaagccatga tccagcctgt tctagtgcgc ctttttcaat atgaatatcg tatttttggt
    14881 tatcaacatg tacagtaagc attcgtttca cttctttctt ttaaaaagct ggaattaatc
    14941 gagtgtctga atcttttcca ttgcttcttt catgatcgca acttctttca tcatgcgtga
    15001 gtaagtcttt tcattcaacg attggggacc gtctgaccaa gcatttgcag gatcaggatg
    15061 gatctctacg atcatgccat ctgctccgct tgccacaccc gcacgagcca ttggtggtac
    15121 aagttcccaa attcctgtac catgacttgg atcaacaatc acagggaaat gagttaattt
    15181 tttcatcaat gggacagcac ttaaatcaaa cgtattacgt gtcgctgttt cgtaagtccg
    15241 aatcccacgt tcgataaaaa tgacaggaga tttgtcttcg actgcaatgt attctgcagc
    15301 attaagccat tcattgatcg taccggaaat tccacgtttc aatccaacag gtttacctgt
    15361 tttaccgaca gcagatagca gtttaaaatt ttgcatatta cgtgcgccaa tctgtaggat
    15421 atcgctgtac tcagccacca tatcgatatg cccttcatcc atcacttcag taatcacttt
    15481 cattccaaat tcatcagccg cttgacggat gtatttcaat ccttcttctt ctaaaccttg
    15541 gaaagcatat ggagaagtac gtggtttgaa ggcaccacct cgcagaattt ttgcgccccc
    15601 ggctttggcc attcgcgcac attctctgat ttggtctaat ccttcgatag aacaaggacc
    15661 agccatcgtc acgaaactgc cgtcaccaat ttttactccg tctacatcca cgactgtatt
    15721 gccaggatgg aattctcgag aagtcaattt gtatgtgttt aaaatacgca cagcattttc
    15781 tactccttca tagcgtgtaa atgctccttc ttgtaaactt cgcgtatcac cttttagtcc
    15841 aatcactact cgttctgttc cttgatcgat tgagactttg aatccttctt tttcgatatg
    15901 atcgacgact ttttttattt gttcttccgt tgcttctttt ttcataatta ctatcattgt
    15961 ttttcccgct ttcttttgtt tacttatcta tcttggctga ttttctctac tttttcaagg
    16021 tggttttaca ttaattccta ctaaatgacc gtgtcctgtt gttctcattt tcgctccttc
    16081 tttcctactt atgacccaga taatcaacaa aaaaagatgt ccctgtagga aattgcctct
    16141 acagtgaaca tcttcaacga gccttaaaaa gcgctgcaaa aatataaaat agccactata
    16201 gatgaatttc tctacgtggc tgtaagtcgt gtttaaaaat ctttagccat catagataca
    16261 aacctggttt gtttgtaccc acgaagtcat gaatacaaac ctatctaaaa tagctaaagt
    16321 aatacgtatt cagttttgta agttttctag atttcataaa aaatcgctcc aaactgatgt
    16381 aagaattgta cctagtatag acataaaaaa atcgactgtc aatcattttt atgaaacttt
    16441 ttttaatttt ctgatagtta actttgtttt tcagaaaaat aacaattggt tttattgaag
    16501 aaaatagtca tgaacaaaag tatctgagaa cttttttact ctcttgttca tgacatatag
    16561 aataaagcag ctttgtcttg taaactccgt ttttcaaata ataatctaaa gattgctact
    16621 gaataataaa gccgatttca tggtcctctt cgctgctgat tcggtaaggt gactcaacat
    16681 ccgctcccca gctattgata cccccgactc ctcttacttt tgcaaaaatc gtaagaaccg
    16741 ttcgtctttc tggcggtagt tcttctatat gtgttgcctg ttccagttct tctgctttga
    16801 atggtaaagc ggaaaaagca aatggcgtat cctgctgttc aaatcgcaac gaaaaatctt
    16861 cttgatcttt atccgtatta tccaacgttt gatttcttgt tagttctacc catttcgttt
    16921 ccatatgcat gccgcattct tggggaacaa ggtatgggga aacggggagt cctgccactt
    16981 tataaatacc ttcgacacca ccagccatcc gatccggata tgtttcccct gataggcctt
    17041 catactcaaa aaattttgct ttcgttggca taatgaacct taaacccaat gcgggtaatt
    17101 ccggtaatcc tttttgtcca taataatgca tattgacaag cattttaccc tctccagcga
    17161 tttggtagga aattgtcact tgggtttttg gtactgtgtt gatttccagt gtaaaaatga
    17221 tttcaaccgt ttcagcgtat tcattacttg aatattgatt atttactgga gcaatcggca
    17281 aatcgatctt tttattgtcc accagtactt ctatttcttt gacttttgga tacaatccgg
    17341 ctcctaacca cataccggat ttaaatccaa atccgctacc tctgtcatta tcggtcgttg
    17401 ctcgccaaaa aactggaagt gtttcccggt atagccattc ttttccgttt ttattgagcg
    17461 attccagtcc gcctcttgta taagaaaaaa tataatgcgt attccccgat ttgacaccta
    17521 atgtacagtc gccgaagacg attgcaactt tttccgtatc catatgactt ttatttactg
    17581 tatttttcat aataatatct tacctcctgc atggcgggtt tttcttgtcc atctgcaaaa
    17641 acgatcccat tccctgagaa ttcatagtca cttggtttat cgtcaaagtc accgccatag
    17701 cgcatcactt ctctgcctgt gattggatca gtcacttgga tcgcctgatc tttaaaatcc
    17761 catatatagc ctccttggta catttcataa cgatcaagca acgtcatgta agaatccatt
    17821 ccacctaacg aattccccat gtcatgcata tattcacata agatgaacgg tttttccgct
    17881 ttattttcaa ggtagtcaat gatctcttct ggtggcgcat acatgcagct ttttacatct
    17941 gaaatcgaat cttcgaatgc tggatttgga aaattccctt cataatggac aagtcgatcg
    18001 gggtctactt ttttgaagta atcgttcatt tgtcgaatgt tttcttccgc ataagattca
    18061 tttccaagag accaaaaaag aatacttgga tggtttttta atgtttcgaa attcgttttt
    18121 gctcgatcaa gaacagccgc ctgccactga ggtactgcac ctggtacgtt gtaagaaggc
    18181 tcaaatgcgc ccattttttg ccatgagcca tgggattcga ggttcgtttc cgccatcaca
    18241 tggattcctg cttggtcgca taaataatac caagtgatct ggttggggta atgagatgtc
    18301 cgtacgccgt tgatctttgc attttttatg atagccaaat ctttttccat atcttctata
    18361 gtgatggcgc gtcctttttt cggatgccac tcatgtcgat ttaccccgtt gataatcatc
    18421 cgttttccat tgaagtagat gattttatct ttgatttcga ttttacgaaa accgaaggaa
    18481 tagtcaatat actccgttac tcttttttct tcgtctatcg tctccaattc aagcttatat
    18541 aaattgggct gaaaatgccc ccacagtgcc acattttcaa atccatcgat gcgaatcgtc
    18601 atttgctctt ttaacggata ttgctgttga tagatttcct tcccatcagg atctagtatc
    18661 gctacattca gctgactgtt tttggctact tgctcaaaag acaaatctac ttcaagtttg
    18721 ccattttgac atttgtcatc taagcgaggt ttgatccaaa gatcttctaa atggttttgt
    18781 cctcgagcaa ctaagaagac atctctgaag atcccaaaaa atcggaaaaa gtcctgatct
    18841 tccaagaatg cagctgtact tcttttgtaa acctccacag ctagaatatt ttcttcttcc
    18901 aaataaggtg ttaaatcaaa ttcagacgga gtgaacgaat cttcggcata cccgataaaa
    18961 tgaccattca accaaataaa cattgcttgt tctacaccag caaaatgaat cgagatttgt
    19021 tttcccttta gaccttcttc taatcgaaaa gtcgtcaaat acgaaccaac cggattgtct
    19081 ttagcagctg aaaagatccc ttccgcctct ttctcagggc ttgtcgtgaa agggggacgg
    19141 cgaaatacat gtccctccca cggatacatc gtattgatgt aatggatctt gtcataattt
    19201 gctaattcaa tatgactagg aacagtgatt tcatcaaaag aacaggcatc aaaatctttt
    19261 ttataaaatg tttttggtcg taccgaagga tttggcgaat aacaaaaacg ccatgatcca
    19321 tttaaagact gtttaaggga ggatgtggtt tctacttctt cccttgttgc ataacaaaca
    19381 tgatcgctat gtgcatttga ttggttcact ctaaaaactt gtggatcatc taaccatttt
    19441 atatttgctt tcatactttt ttccttctct ctcataactt tttgaaatga agcagttctg
    19501 tttggaaatc accttgaaaa tcggggaagt aaagtccaac tgtcatcaat tcggcccccg
    19561 aaaatatccg cttcgaggtc tgttcctgat aaagtgcctc atcatctaac cccatcagat
    19621 atacttcatg gaacgctggt tgagctgaag ctagtatcct ccctaaaaac acaatagctt
    19681 catcttgttt aggagacaca aacatccatg cggcaatatt ttcttcaaaa ggactcgcca
    19741 aacgataata atggccatac tggatcaccg gacgaatcgt ttgataggat ataatttggt
    19801 cttttacttg ctttttttct tcaggagaca gctttgtcaa atccagttca taaccaaaaa
    19861 cagcgctcat agctgtttct cctcttgttt tcaacgaagt agatctgtcg gtctgatgat
    19921 ttggtacagc tgatacatga gctgtgatgg acgaaatcgg ataagcaagg cttgttccat
    19981 attggatttt catacgctcc actgcatccg tgttatcact tgtccatgac tgcggcatat
    20041 aataaataaa cccggcatca aaccgtccac ctccaccaga acagccttcc cataagattt
    20101 ccggataatc agttgtcaaa tgttcaagta gttcataaag cccgagcata taacgatgcg
    20161 ctacttctcc ttgtctctgt gggtcaaggg taatcgaata gacatctgaa agcgaacggt
    20221 tcatatccca tttgatgtag tcaagaggaa tcgtatctaa aatctttctc atttgtttct
    20281 caatcgtctg ccgaacatct aaccttgtaa aatccagtac atgttgtgat ctggaagcag
    20341 aaggcattct acctggctcc tgcataagaa aatcaggatg tgttcgatac agttcagaat
    20401 caaccgagat catttcaggt tcaaaccata aaccaaattt caatcctttg ctatgagcat
    20461 aatctgctat ttcacgtaat ccatttgtca acttgccttc atactcgaac cagtctccta
    20521 atgaagaatt gtccgcatct ctttttccaa accagccatc atctaatacg aacatttcga
    20581 tgcctagctc ctttgcttca tcaatgatcg ccttgatttt ttcactattg aagtcaaagt
    20641 aagtggcttc ccagttattg accagaatcg gccgttcagc aaattgatga cgacctcttg
    20701 cgattctttc acgtagcaac tcatggtgga tctgactcat tttgttcaat ccctgacttg
    20761 agtaagaaag gatcatttca ggtgtttgaa aagactggcc tgcattcaat tcccacgaaa
    20821 aacgatggct gttgatccca ccgacgactc tcaattgatt gatctgatct ttttcaagtt
    20881 cgaaagaatg gttgccggaa taaacaaatt gaagtccgat cgcttctcca gtattttctg
    20941 tcgtatgatg atgaactaaa gcaataaagt tattcatatg gtgactgctc gttcctcgac
    21001 ggctttcaaa tacttttgtt ccagataaaa cagattgccg tgaaatctgt ctttcattga
    21061 catgtgctcc tggcaaagca atgacttcat caaatcgcct agtatgggca aagtctagct
    21121 ggaaactagc cgctttttct agtttgattg tttctccggt ttcatttctt atctttacag
    21181 atcgtgtgat cactgctcta tcagtaaata tggtatagaa caaatcgaaa taaatcgctg
    21241 tttctctatc cttaagtgaa atcaccaacg tttgtgcctc tgacttgtcc atcacataag
    21301 tttgaggcaa gccttcgatc tctggcttcc catctgtaat ataatggctg tcatatctca
    21361 gatccagtaa gtctgatcca ttcttgcgct gaatgatcga tgcgggcgtt cgaaagtcca
    21421 tgctgccatg agaagagtat tcttgcggta gtgtatcttt cgacagagac cggtcaggat
    21481 ttaagggaac atttcctgaa aatccacgat ctcttcgggg ataattttta ttgtctttgt
    21541 actgcttgac tggtttgcca aaataaatat gcgccaatac attgctttct tctatcttta
    21601 tcagataaga aagaaatgta tttcgtaaat ggaagactcg gctcttttca tcaaataaga
    21661 tgaaattttt atctgttttt ctatgcgtaa tatccatcat ttcactccca acaaaacgga
    21721 aaccgtttac ttttttttat aattcctgta tactgtttac taaacaattt tgtcaataaa
    21781 aattttttat ttttttgagg agtgtgtaaa aatggttgga attagagatg tcgcacgaaa
    21841 ggcaaatgtc tctcctgcta cagtttcccg tgtgttgaat aacgatcaga cgatccatgt
    21901 ggctcagact actcggcaac ggatagtaga ggcagctgct gcgttggatt atgacatcag
    21961 tactcgtaaa tatatcaaaa agagaatgcc ttcgattggt gtgatctcta cgatcggcaa
    22021 agcgagcgaa gaacaggata tctattacaa acatttgcga gtagggatgg aagaagaagc
    22081 tcgacgtctg catttaggga tgaatcgaat ctataatcta tctgataatc ctaaacaatg
    22141 ggaagatcta gatcagttag gtgcggtgat cgttgttggg actgttacga aagaatcgat
    22201 taccgccttg ttaaaacaaa acatgcaaat agtcgtcgtg gataaccctg acatccagca
    22261 agaggtcgat atggtgtatg cagatcttga acggatgact aaaaccgtac tggaattgtt
    22321 cttagaaaat ggtcataaaa gaatagccta tatcggggga tataaagtcg atatggatga
    22381 attcggtggg aagcagattt ctataaatga aaagaggatg cgtgcctatc agcattttat
    22441 gatcgatcat cacttagaaa aatatatgtc ttatcatcta ggtggctgga cagaaaaaca
    22501 aggtgaggta cttgcgacta atctattaga aaatgaatcc cctcttccta ctgccattct
    22561 tgtcgggagc gatccaatgg caattggtgt ctatcgggca ttgaaacaaa aaaatatcca
    22621 aattggagaa gagattgttg tagcaagctt tgataatatc gagacaatcg caaacctctc
    22681 ccctggcttg accagtgttc aaatcaatgc gaaatcaatt gggcaagcag ctgttcgaat
    22741 ggcattggag cgaattgacg gtatacggga cgaaccaatc attttgactt atcctgcacg
    22801 attgattgtt agggaaagtt ttatcccaag aacaaaaagg tattgaaaga gaggttgtga
    22861 aaagccgctt cgtttcttca tactcaaaac gaaacggctt tttcacaacc tcttacttat
    22921 acttattcac aaaatccaat gtctgctggt aacaattttg cgattctttt agcgtgtaat
    22981 caaattggta ttcatgggta atctcttttt ttgtatctgt ataaaacaag gattgcacgg
    23041 gtacctttaa ttctgtcaac cgattttcta atgcttgacc ttgctcctgg aatgagtatg
    23101 catttccgtc agttatatac gttggcggaa attccttaga aacatggtca gccacactag
    23161 cttctttcaa ttgctcactc gttttccaat cttttgttcc aatcaacgac cacgcaacgg
    23221 ttttgacgaa aaacttcata aatcgatcat ccgaatgctg ctgtgctgtt agcttcaaat
    23281 caacaggtcc gcaataagaa atggttcctt tcagactatc ttttggaagt agctgtttga
    23341 ttttcatttg tttagcatac gcatcattcg tttgtatagc tgcatattgc aatgcgattt
    23401 gtgaacctgc actatctcca ccaaaaaata attgttccat gtctagcaat ttgtcgtctt
    23461 tttcttcagc taataaatct ttgatcagtt cattcacttg aagaacttga ttagggtatt
    23521 ctgaatcagg cgctaattca taattcatcg caaccactgc gatgttggcg tctgaaacta
    23581 attttgtcgc aaattctttg acacccgatt tatctccgcc gacgaatcct ccaccatgta
    23641 cccaaaatag aacaggaaca ggccccttgc tgttttttgg atagtagatg tcataagtat
    23701 tctctttata cttggactca tacgtcaaat ctgttttttt cgccacgttt ttttctgctt
    23761 gatcgaacgt ttttttatca gtgatttgaa cagtatttga aaacatatgg ttgatcaaga
    23821 atgctccagg tctgggggaa agctggaagg caagaaagat tgcaaacgcg atcccaagaa
    23881 tgattccgaa gaaccatccg ataaatttaa gaattttctt tttcataagg ctccctcagt
    23941 agttagtatt aagcattctg attataccat agtgttattt cctatcaagc tctcctagat
    24001 gatttaatga ttttccccaa acttcttctg caatgctttt gacaaaagaa attttttcca
    24061 ttgttcttca aacaaaacat tttcttcttc tgttgaagca aatccacatt gaggacttaa
    24121 gcacaaacga tccaaaggca gatatcgtgt cgcttcgtag atccggtcaa tcacttgctg
    24181 gtgctcttcc atttcgccat ttttcgttac agtcaaaatc taagacaact aatttatctt
    24241 cagagacttt ctctaaaaga acaaaactcc cagcacgttc actatcgtat tctaaataat
    24301 aggcacggac attttcttga gtaaaataat gggtctgcta cgtcgtcatc ccccctgatg
    24361 ccgccaaaat cgaataataa tttccgcgtc aaacatgtat atttagtgtt gaatcatttg
    24421 agaatatgaa aataaaaatc tttttgatca atcagttaat caaattgaaa taacgaaaaa
    24481 tctgagacag aatgacgttc attctgaccc agatttgatt ttgcacaact caacagtcct
    24541 tattggcaaa tcgccaaaat aatgtagact aactaaa
//
LOCUS       DAYNVV010000039        24271 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.039, whole genome shotgun sequence.
ACCESSION   DAYNVV010000039 DAYNVV010000000
VERSION     DAYNVV010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.039"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..572
                     /locus_tag="ACGXWR_001791"
     CDS             <1..572
                     /locus_tag="ACGXWR_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFK0803348.1"
                     /translation="ASRIAIMSEGRVIQFDTPENILRHPANDFVEELIGEDRLLQAKP
                     NATRVGEVMLNTAITITPEKSLQEAIKLMREKRVDTLLVTDNSNVLKGFIDVETLNKK
                     RGKVSSVGDILNKHVFYVKESAYLRDTLQRILKRGLKYVPVVDEQNKVVGILTRASLV
                     DIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            576..1217
                     /locus_tag="ACGXWR_001792"
     CDS             576..1217
                     /locus_tag="ACGXWR_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0803349.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            1214..2131
                     /locus_tag="ACGXWR_001793"
     CDS             1214..2131
                     /locus_tag="ACGXWR_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HFK0803350.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            2128..2799
                     /locus_tag="ACGXWR_001794"
     CDS             2128..2799
                     /locus_tag="ACGXWR_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0803351.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(3340..3828)
                     /locus_tag="ACGXWR_001795"
     CDS             complement(3340..3828)
                     /locus_tag="ACGXWR_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HFK0803352.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(4029..4295)
                     /locus_tag="ACGXWR_001796"
     CDS             complement(4029..4295)
                     /locus_tag="ACGXWR_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFK0803353.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(4295..4558)
                     /locus_tag="ACGXWR_001797"
     CDS             complement(4295..4558)
                     /locus_tag="ACGXWR_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFK0803354.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            5079..5219
                     /locus_tag="ACGXWR_001798"
                     /pseudo
     CDS             5079..5219
                     /locus_tag="ACGXWR_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(5361..7184)
                     /locus_tag="ACGXWR_001799"
     CDS             complement(5361..7184)
                     /locus_tag="ACGXWR_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFK0803355.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(7782..10487)
                     /locus_tag="ACGXWR_001800"
     CDS             complement(7782..10487)
                     /locus_tag="ACGXWR_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HFK0803356.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(10793..11740)
                     /locus_tag="ACGXWR_001801"
     CDS             complement(10793..11740)
                     /locus_tag="ACGXWR_001801"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HFK0803357.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            11930..12199
                     /gene="rpsN"
                     /locus_tag="ACGXWR_001802"
     CDS             11930..12199
                     /gene="rpsN"
                     /locus_tag="ACGXWR_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFK0803358.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLHKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(12375..12737)
                     /locus_tag="ACGXWR_001803"
     CDS             complement(12375..12737)
                     /locus_tag="ACGXWR_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFK0803359.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(12748..13869)
                     /gene="alr"
                     /locus_tag="ACGXWR_001804"
     CDS             complement(12748..13869)
                     /gene="alr"
                     /locus_tag="ACGXWR_001804"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFK0803360.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(13885..14235)
                     /gene="acpS"
                     /locus_tag="ACGXWR_001805"
     CDS             complement(13885..14235)
                     /gene="acpS"
                     /locus_tag="ACGXWR_001805"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HFK0803361.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(14365..15876)
                     /locus_tag="ACGXWR_001806"
     CDS             complement(14365..15876)
                     /locus_tag="ACGXWR_001806"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFK0803362.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(16198..17550)
                     /gene="murF"
                     /locus_tag="ACGXWR_001807"
     CDS             complement(16198..17550)
                     /gene="murF"
                     /locus_tag="ACGXWR_001807"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HFK0803363.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(17703..18779)
                     /locus_tag="ACGXWR_001808"
     CDS             complement(17703..18779)
                     /locus_tag="ACGXWR_001808"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFK0803364.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYAYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            18975..20720
                     /locus_tag="ACGXWR_001809"
     CDS             18975..20720
                     /locus_tag="ACGXWR_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/UbiB family protein"
                     /protein_id="HFK0803365.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(21000..21437)
                     /locus_tag="ACGXWR_001810"
     CDS             complement(21000..21437)
                     /locus_tag="ACGXWR_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HFK0803366.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(21421..22794)
                     /locus_tag="ACGXWR_001811"
     CDS             complement(21421..22794)
                     /locus_tag="ACGXWR_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803367.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(23116..23604)
                     /locus_tag="ACGXWR_001812"
     CDS             complement(23116..23604)
                     /locus_tag="ACGXWR_001812"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFK0803368.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(23626..24228)
                     /locus_tag="ACGXWR_001813"
     CDS             complement(23626..24228)
                     /locus_tag="ACGXWR_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFK0803369.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         6960 a         5163 c         4488 g         7660 t
ORIGIN      
        1 tagcaagccg tatcgccatc atgagtgaag gccgtgtgat ccaatttgat acaccagaaa
       61 atattttacg tcatcctgca aacgatttcg tagaagagtt gattggagaa gatcgcctac
      121 tacaagccaa gccaaatgcg acaagagtcg gcgaagttat gctaaataca gcaatcacga
      181 ttacaccgga aaaatcatta caagaagcaa tcaaactgat gagggaaaaa cgtgtagata
      241 cgttgttagt taccgataat tcgaatgtat taaaaggatt tatcgatgta gaaacgttga
      301 ataaaaaacg aggaaaagta tccagtgtcg gcgacatttt gaataaacat gttttttacg
      361 taaaagaatc cgcctatctt cgtgatacct tgcaacgcat tttaaaacgc gggctgaaat
      421 acgtgccggt cgttgatgaa cagaacaaag tcgtaggtat cctgactcgt gcatcattag
      481 tggatatcgt ctacgatgtg atttggggag aagatcccgc aactactgat gttgcagagt
      541 cagctactcc tgaagaatct aaggaggtct gacctatgca gcagtttttt catcagcacg
      601 gttcagaaat tctctcaaaa ggttttgaac atctttatat ttcaggactt gctttgatca
      661 ttggtatcat cattgctgta ccgcttggtg tcttactgac acgttttcca aaagctgcca
      721 cgattgtgat tggcttaacc agtgccttgc agacaatccc ttctcttgct ttattggcat
      781 tgatgatccc gctatttggc gtaggtaaat tacctgcgat tatcgcactc tttatttatt
      841 cattattgcc gattttacgt aatacgtaca ttgggatgaa aaatgtcgat tggaattatc
      901 gggatgtggc aaaaggcatg gggatgactg agttccaatc cattttttcc gttgaattgc
      961 ccattgctat gccaacgatc atggctggta ttcgtttagc tgccgtttac gtgattgcat
     1021 gggctacact tgcctcttat atcggcgctg gtggtttagg cgatttgatt tttagtggac
     1081 tgaataatta ccaaccagat ctcattttgg caggtacgat ccctgtaaca attttagcac
     1141 tattggctga ttggcttcta ggtctcttgg aacaccggct gacaccgatc gcacttagag
     1201 aggagaatga agaatgaaac gtatactaaa aatgaccatg gttcttttct ctcttcttat
     1261 acttgcgagt tgttccttcc ctggtcttgc cagcaataca gatgaagaca ccatttcgat
     1321 cacaggtgga atcacttcag aagcacagat cttagcaagt ctagttgccg gaatggttga
     1381 acattataca gataaaaata ccgcaatcat caacaatctg gctactacaa ctatcaacca
     1441 tcaagcgatg atgaacggag atgcttcaat ttcagcggct cgctacacag gaacagattt
     1501 aacgactaca ttgaaccttc ctcctgaaaa agatccgaaa aaagcgtttg ctaccgtgaa
     1561 agatgaattt gagaaaagat acggtcaaac gtggttcccg tcctatggtt ttgaaaatac
     1621 gtatgtcttt cttgttcgaa aagacaccgc acaaaaatac catctatcta aagtcagcga
     1681 tctgaaaaat gtagcggatg aattagtagc tggtgtagat acttcttgga tcaatcgtaa
     1741 aggagacggt tatgacggct tccaagaaac ttatggcttc tccttcaatt cgatattacc
     1801 tatgcagatt ggacttgttt atgacgcagt cgaagcagga aaaatggata ttgttcttgg
     1861 ctactctacg gatggacgga tcgccagtta tgatctagtc atgttggaag atgatcgtca
     1921 attcttccca ccatatgatg ctgctccagt tgtagacaac aagatattag ctgatacgcc
     1981 tcatttaaaa gaagccttaa ataagttagg tcataccatc agtacggaaa aaatgcagga
     2041 attgaactac gaagcagata ataatctagt ggaaccatca gtagtagcac aacgtttctt
     2101 acaagaaaac cactattttg aagggaagtg aagcaattgg ataaaatgaa tgtctttcaa
     2161 caatttttct attatttcca ggaaaatggc tcctatatct ttgcacaatt tatccgtcac
     2221 ttcctgattt ctatctatgg tgtcctcttt gcagcagttg tcgggattcc ggttgggatc
     2281 atgatttcta ggagacgtaa attagcaaac tgggtgattc gtttggcgaa tatcatccag
     2341 acgatccctt ctctagccat gatctccatt ttaatcattg gattaggcct gggagtcaat
     2401 gtcgtgattg ttactgtatt tttgtattcc ctcttaccga tcatcaagaa tacgtatacc
     2461 gggatgatcc aagtagacaa aaacatcctt gatgtcggca aaggcatggg gatgactgct
     2521 agacaacgac tattcatggt agagttacca ctctctgttt ctgttatcat ggcaggcata
     2581 agaaacgcgt tagttgttgc catcgggata accgcgatcg gtgcattcgt cggtgctggt
     2641 ggtcttggag atatcattat ccgaggaacc aatgcaacag agggcacatc gattatttta
     2701 gcaggtgcat tgccaactgc attaatggcg atcatcacgg actggctttt aggtattttg
     2761 gaaagacggc tagatccagc cagccgtaca tcacgctgat gttattgtaa aaaacaaaag
     2821 cttctgcgac catttgttgg tcgcaaaggc ttttttagtt ctgtcatttt taaggcaata
     2881 atccactctg attcttccct ccttatgggc aaagagttgc ttttcttagc tatttatcca
     2941 ttccgtatac tccaacttca tactgccaac gggttcatat ctgcatccac cgactaagtt
     3001 tttttcttat ccgctaaggc attttgccaa tccattttcc catcactcgt catggaattc
     3061 ataccacatg atctctaaat actcgtctgc ttgttctttg aattgggcat caattcttac
     3121 atcctttggc gtggctttca tttaagcctt ttccatcagt cctcgattgt tcgatgcctt
     3181 cagctgcatc atcaaaactg gtgactgccg tatcggtaac ttcgatcatc ttttatacaa
     3241 tcgggaactt gccatcctca tccttggcta aaaacatatc tagccattcc agcttctcgc
     3301 catgggaggt ttgcggttcc taaaaccggt acacgattct tatggactgc atccgtcgca
     3361 actagacttg gcgatacgat gatccttcac cagaagagca cccccgtaaa ccaattgatc
     3421 gatatattgc caataagaaa agacattggc gtaaaagata tcgatccctc gtgatgcatt
     3481 gccgttgata ctgctattca tggccgaaag cgccacgact ttaacttctt ccgtttgagt
     3541 gacattcatg ttcggcaatg tcgctttgga tacccgctct gctaaaggaa cgacactggt
     3601 attgtatttc gtatctgtat cttttccaaa agaccatgcc aacgaatcct ctgggaacca
     3661 ataagacgac tccggttgat tgtccattgc ttttttcaac atacttttgg ctgtttctcg
     3721 ataaacgaca tttccaattg tcttcgcctc actttggcga taatcgatgg tcgttgccac
     3781 tgccaacact aacaacgatg ctccaatttt actgattttc cttgtcacac ttcttcctcc
     3841 ttgttttaca taaacccgtc aacattccat tcctaaactc aaacaatgac ccttcaaagg
     3901 tggagatata ggaacaaatt aaagaaatca tgcaataaat ccaagaaggt tggttttaga
     3961 acaaaaaaag agtctccttt ttggggagac tctttgttaa ctatctaaaa aggttggctc
     4021 ttctcacttc actcataatg tgtccaggca gaataaattt ctacaacttt attttcctca
     4081 tcaactttgt aaaccactcg atgctgtcta ttcagcctgc gtgagtatct gccttcatgt
     4141 gtaggtctca gcttttcaaa agactgcgtg ggcatatatg gatcttcctt caatgtctga
     4201 atcacttctt caaattgttt ctttaaattc gtttgcttga tttttcttaa atccactttc
     4261 gcagagtttt tgattgcgac tgtatagtta ctcatcaaag agcttcccaa tcaatatcat
     4321 cgatattcgt aaagctactg tcgtcttttt cgcggtctcg tactttatct aaagtacctg
     4381 tttgctcaag aaaaagggtt tcttgaatcg ctctccagtc ttccagccca atcaatacag
     4441 cattgtttcc actacgatca ctaataatct cgatttcagt atgattttca tttacctctt
     4501 tcaataactg ataaaaattt ttacgagcag tgctaggatt catcgttgta ttagccattg
     4561 tctctcctcc tttttctgat ataattatag cgtacttgat taagtacgtc aaaaaaatac
     4621 aataaagcac ttaaattcag caaacttttc ctctttttta catagagaaa aagacccctt
     4681 tttagggagg atctttgtcc acgctcactt cttactcctt tacgactagc ggtagccaaa
     4741 cgtaaagtaa ttggtaacaa cgtatcatct ttagcaaagg tcgaatccaa agcctgtgag
     4801 tctatgcaac aacaccaata cacgaaggtt cctcgttgca gtgtgacttg attgatatct
     4861 tgaataacct gaggatacgc acgaaagatt tgtaacggtt attcaaaact gattttggcc
     4921 gtcaagtctt ctactgcctc aaaaatgatt gcctctttcg tctcctgtca ttcatgttca
     4981 ctatcgattt gatacttgct tagaccgttg ggtttgtgaa tcaccaatta aaaatggcac
     5041 tgagttatgg taacaaaaaa tggtcacttg acgaggctga gattcctact tatgaagaca
     5101 catggcactt aagagtcgag gtaaaggaag aagctgaaaa tataggaggc tgtacattat
     5161 ttggcaaagg attcggaaat tatgatcaag acatcaaaat caaaatgttt tacagctaaa
     5221 taggaagaat aataacattt catacgctgt tcccatcttt aatggcttat agagggcacc
     5281 tttagctgag aataagacaa aacagaccct ctagcttcaa ttaagagcta gagggtctgt
     5341 ttttgatttt aaaacttggt ttatttcttc aaatggtagc tataggtgct gacaacgata
     5401 ttttcacgcc aagacaatcg caatcttaac cgcaaacttg tttggttatg gagaatattc
     5461 tgccagcgtc tgtttggtac aaattgagga atcaacacag tagttgtata gttttgtttc
     5521 gctgcatttt tacttacgat atctacataa cggataattg gattttcaat cgagcgataa
     5581 gaagagtgga cgattgaaaa acggacatct gggaaatgct ttttaaattc tgcttcgatt
     5641 tctttttctt tttcgacatc ttcgtctagc gaaacatgca tcgcaacgac ataatcaccg
     5701 atcgaacgtg cgtaattcaa cgcaccgata tttacccgtg tcacattccc gactaataca
     5761 agaacggtat tcccgtcata atcatgtagt tttgcatcat tttctaaacg aagctgttct
     5821 gctacttttt tataatgatc atggatctta taaaaaatga acataacgat tggcataatg
     5881 atgaagaaag gccaaatgtc ccctaaccga tagacaaaca aaatcgcaat gattgcatat
     5941 gagatgaacg cacccgtaat attggcaatc gatttgctta accatctttt tccttctttt
     6001 ttccatttga cgaccatccc tgtttgagat aaagcaaatg gaatgaacac gccgatagag
     6061 tataacggaa tcaagcgttc tgttgagcca tggaaaataa acagcaatac gatcgaacct
     6121 agcgctagtg tgataatccc attggaatag cctagtcgat ccccacgatc ttgatacatg
     6181 tgaggcatga atttatcttt tgccagattg tatgcaagaa ctggaaaagc agaaaaaccg
     6241 gtgttagcag caactgctaa aatcagcgct gtagcaaatt gaaggacgta atacaaaata
     6301 ccatgtccaa agacagcttt accaatttga gacaaaacag tgacttcttt ttcaggaacg
     6361 atcccatacc aatagttgat aaatgtgatc cccacgaaga agaaacctaa gatcaatgcc
     6421 atcatcgtca atgtagcagc ggcatttttt gctcttggct tcttaaagaa tggtacagca
     6481 ttactaatcg cctccacccc agttaaagag gaagaaccag aagaaaatgc tcgtaaaatc
     6541 aaagcgatag aaacacccgg cacagccgct cctggaagtg cagtagcttg caatggcaca
     6601 gcacctgtca cgatattata taaaccaaca acgatcagta acgagatcac aaggataaat
     6661 gtgtacaccg gaaataatag gaacgatgca gattccctca gcccacgaag attcagcatc
     6721 atcagtagca aaacgattgt cacagaaata gcgacttgat gaccgtagag tgctggcacc
     6781 gctgatgtga tcgcttcagc acctgctgag acagatactg ctactgtcaa catgtagtcg
     6841 atcaataaag agccaccgga aatcaagcca gcattctttc caagattctc actgctgacg
     6901 acatatgctc ccccgccatg aggataagca tggatgattt gacgatatga tagcgttaat
     6961 gaaatcaata aaataataac aaaagcggca atgggtagcg aataccagat ggctgcagca
     7021 gacaaagcga ctaaaacgac aacgatttgt tccgtaccat atgcaataga tgataacgca
     7081 tcagacgaca ataatgccaa agcagcaaat cgggttaatt tgtgctcatc attttcagca
     7141 gattttaaag gcttacctac taacaacctt tttaagtaat ccaatttcta aactccttta
     7201 cacacaattt tacttcaagt tttatagtcg aaaatttata gtaaacaaga tgttatagta
     7261 cgctcactga ccttaaaagt caataaactt taagaaaata attggaaaaa aacagaaaaa
     7321 tatcaagcgc tttttcaaac gctttaatac agcaaaaatc taacattttt ttatgggctt
     7381 tttctttgaa ttctataata aaaggataga acttgactta gaaaatcaag ttctatcctt
     7441 tttgatatct taacttttgg aagagagatg taaggctgct ttctacccat cattcttact
     7501 actcgaagca tagcgcagtt gtcacaacct cttgataaac ggtgtttaaa agcttgcatc
     7561 tgcggtaata agctcaacca aattaaaaac ataagaagct gtttttattt ggtcgttctt
     7621 attacttgat gcagagcagc ttttttacaa cctcttggta cacggtgttc aatcagctga
     7681 ccctcggtat tagctcaaaa aaacggcaaa atatgaggaa ctatttttcc atttttttct
     7741 ctaatactca ggtcaaaaca ctgatttcac aacctctttt tttaatgaaa aatatggctc
     7801 tcatgcgccg cttctttgaa tttcgtcatt ttttcttcga tgaacggata gattgccgtt
     7861 cctacgattc caaagacaac aaacaaaccg atcatgatcc agattgcttt cgtagcattt
     7921 ggccaataaa ttcctcctgc agattcccgt aacaagttta ccgcatgagt aaatggcaag
     7981 aacggattga tcatttggaa gaatttccct gagacttgga tcggatagtt cccgcctccg
     8041 ccagagatcg acagtactaa gatgataata gcgatccctt taccgacatt atcgaataat
     8101 gcagccaaga catagacgat catcatgaac gctaaggcga tcaagacagc aaatgacacg
     8161 ctgtagaccg gattttggac atctactcct agtaagaaaa tattccctaa tgtaacgatc
     8221 aagctttgcg caatcgccat tgtcaaaaat gtcagcatac gagcaacgaa ttgttctcgt
     8281 ttcgtaaaat tgtttcggtc tttctttcct aaatagtatt ctgtcgtagc aacacttgaa
     8341 agaagaacag cgccgaccca cagacatagt gcagtataaa acggggtgct agctgaaccg
     8401 ttatttgcga ttggataaag cgcattggtt tgtagctcaa caggttgtgt aaagaagtca
     8461 ctttcttttg ttgcgtctag tttcaataat ttgatgactt cgcctagatc gacttcttgt
     8521 tcgccttttc ggatcgcgtc tgctgctttt tggataccag ctttgatatt tggccagtca
     8581 ttgttgatca agtccgcagc agcgttcaca gctgtttcga cttctggcat tttttcattt
     8641 actgttgtca atgtaccggt gatttcattt tttagtgctg gccaatcatt ttggataaaa
     8701 tcagcggcca atcctaattt ttgctgaatg atcggtaatt cattgttgta taggtctgcc
     8761 ccttcattga tgccattgac gatggtatcc atatttccat tcagcattgt attggcatca
     8821 tggatttctt gtccaattgc aggcatttct ttttgatatt tttctaaaat tgccactgca
     8881 ttcgttacag ttgctttcgt tgagctgaga agcgaatcaa agtcgatctg gtccgctttg
     8941 ctcagtgcgc cttgtgcagt cccaatcgta tcgatgactt ggtctagtag agaagtgaca
     9001 gtggaactga tttgacctgt attgatacca gcaatgatgc cattgatatt attaacaacg
     9061 gcatcaattt gatctagcaa ttcatcaata gccttcgtgt cttcattttg aacagctgtg
     9121 ttcaaagcag ataggcggtt ttgcagattg cttagcaagg gttttaattg atttagctga
     9181 tcaataattg gctgtaattt cgtatttcca gcacttgttt gcaatttagt caggaactcg
     9241 accagtttat cgattgcatt ttgttgttga gatattccgt caataaagcc gttcaataca
     9301 ttgctgatgt ttttcttttc atcatcagtc agcttaccat cttcaatagc tgttcttaca
     9361 gtatctatta acgaacctgt cgttgttgcc acttgtccaa ttgacttcaa tgtaacatct
     9421 acactgtttg tgatgcttgg tatcgcatct ttcagctgag aggcacctga ttttgtttgg
     9481 tttgctagat cacttgcctg attttctaaa tttttcacat ctggcaagat atcttgtact
     9541 tgttggatga tcgtcaagcc ttgttttgct tcatcgattc cttggttcat tgtctcttgg
     9601 atcgaagcaa aatcgccgtc gatctctgct agttgcttac cggcattttg gatctctggg
     9661 attttttctt gcaaatcaag gatgattttt gcttgatctt tcaactcagg cattttgtca
     9721 ttcaatgcaa cgactttttc acccatctca tctactttag ggatgtaatc cacgaattca
     9781 tttgctttat tcagtttttc cttgatttca ggtagttgac tttgtaattc gaggacttgt
     9841 tttgtgtagc cgtcgatcgt gtccaaattt tcatctgttg ataaaatcat atctttaact
     9901 ttattgatac ttactaggtt cgtatcgatg tcgtaaccta tctcattgaa tactttcaat
     9961 aaagtcgaac tggctgtttt gataaattca tttgtgattt gcgattggat cgaacttgct
    10021 cctttatcgg tgattttcgg tgcaatcgca ttgatttttt catttaccgt atattcgatt
    10081 tttggtttct tgatatcacc actagtaaaa ctcagcagat cttctgagaa atcctttggc
    10141 aagtaaatac ctgcgtaata ctttccggaa cggactccgt cttctaattg ttcttttgaa
    10201 tcaacgaatt gccatcctaa ttgtttattt ttatgaagcg attcgatgac ttgctcccca
    10261 atggccactt ctttaccttg aaactctgct ggcttgtctg cactgtaaac agcaattggc
    10321 agctctccag tatttccata tggatcccat aatgctttga tgttaaacca cgcatatagc
    10381 gaagggatga tcatgatcgc gatgatcaga agtgttgcaa tcgggttttt gaaaatccgt
    10441 ttccagtcaa gcaaatataa tcgaagcgta tttttgattg actgcatagt tctccccctt
    10501 cttctttttt cagctgaatt actttaccat gtatttcata cttttttcaa tcggcttttt
    10561 tcaaaaaagt cgaatttttg gacatatcac ggcaattgtc tcattgtaat ctcttacata
    10621 ttgagaaata attaaggatt acagccttta ctttatcatg aaataaaagg gaaagataat
    10681 tttatgccaa agtttttatc tattatacgt atacgcaaaa aagctaaaac attttttgtc
    10741 tttgccccta caaaaatgtt tcagcttttt tcgtttttta ttcctgtatt tcttattttt
    10801 cgaatgacag gatgattttc ccagcaggag gatgtccttc aactagctga tgtgcttgga
    10861 tgacatgctt aagtgaagca gacagattca ttgaaataaa aacatgaaag gctccttttt
    10921 ggtaggcttt gattatgcca gcaaaggctt ctgcatctag atattccttt cttggaacaa
    10981 acgattcata aaagccttcc tttttttgcc gcaaatctag atctgggagg tcatttaatg
    11041 caacatacct gccgcctggt ttcatgatct ggatgccggt ttctcctttg atacttcctt
    11101 tcgtcgcatc gattacaagg tctgcctgat cagcaaattg cagacctgga tttgttttat
    11161 cataagcagc aaatgctgaa gctcctaatt tttttacctt ttcctcattt ttactggatg
    11221 cactggttaa gattcggatt cccttttcat ggagaagctg gatcagactt gacccgaccg
    11281 cacctgatgc tcctagtatc attacagtat ctgtcggctg gatttccgtc aaatggttga
    11341 ttagattata agccgtaatt cctggcgtga ccattccggc tgcttcttcc caactcattt
    11401 tatctggaat ttttgctact tttgctgatg gcaacacgac ttcttctccg taagtcccgc
    11461 cgactgcatg gacagctact cgatcaccta catgaacagt tgtgacatct gaaccaatct
    11521 ctgtcacaat accagcgcca tcattacctg gtacataagg gaatttcaat gttcgtatct
    11581 ctttcatttc tcctaaacgc aaggcaacat cataaggatt cacactgaat gcttttattt
    11641 ctacacgaac atgtccagaa ccgacttctc tgggatgagc atcgatttct tcaaaaacat
    11701 cttgtgcttc tccgtaaccg ttaattgcaa atcttcgcat ggtcaccatc tccctttttc
    11761 tttaagttta cgtttatgtc tttattttga caaaaaaaat gtcttttcgt tttggcgcat
    11821 gattcaaaac aaaatagttg tcttttttcg cgtaacgtgt taaattattt atctaaaagc
    11881 gtaaagatta cgatttacgc taataaaaaa taattggagg aatttgttga tggctaaaaa
    11941 atcaaagatt gccaaagcaa aaaaacagca agaaacgatt gaacgctatg ctgctttacg
    12001 ccaggaatta aaagcgcaaa aagattacga aggcttgcat aaacttcctt tagatgctcg
    12061 tccagaacga ttgaaaaatc gtgatttaat cgatggacgc cctcgcggat acatgcgtaa
    12121 attcgggatg tcccgtataa aattccgtga attagcacat aaaggtttga ttccaggagt
    12181 aaaaaaagcc agctggtaat ccaagtctgg ctgtaatgta aaggaggagg gcgcatggac
    12241 cactccttgg atcatcaaaa aagatacgtt cgcttcttct agcagaaatg ctggtactag
    12301 aagcagacgt atcttttttt acgcacagct ggtccttttt tatatgtaaa ggctgcatgg
    12361 ttacttcgct atatttattt agtaacagga gtcagtgctt cgatacccac actaattttc
    12421 aatgctcggt caacttctgc cataatgggt cgatccaaat ggcagacctt ttctttcaat
    12481 cttgatttat cgatcgttct gatctgctcc aacaggataa cggagtctct ttctattcct
    12541 gttccagtag ctttgatccc aatgtgagtc ggaagcttag gtttagccat ttttgccgtt
    12601 atggccgcaa caatgatcgt cgggctaaaa tggttaccta gattattttg aataaccaaa
    12661 actgggcgtg ttccgccttg ctccgatccc acgactggag aaagatcagc aaaataaata
    12721 tctcctcttt ttaccatagg atcctcctta ttcttgatat tctcttggta tccgctgtcc
    12781 taatccgcaa gccacttcat agtggatcgt acctaattga tctgctatat cctgcatagt
    12841 gatttctttg tctgcatttt tgccgataag cgtcactttt gttccgacag gaaattcttg
    12901 aggcaatcgg atcatcagtt gatccataca tacacgccca atcgtttcac agtagttccc
    12961 ttctaccaat agagaaaaac cctgcatctt tcgtggccag ccatctgcat aaccgatcgg
    13021 tatcgttccg atccactctg cttcaggagt gatatatgtt tctccatagc cgattccttc
    13081 acctgctggg agttttttga cttgaatcaa ttcagaaacc agctcaagtg ctggctgcaa
    13141 tggataaact tccggtagtg cgtgcccaga gggattaagt ccgtacattg ctactccata
    13201 acgaatcata ttgccgattg tttcatcatg ccataaagcc gttgcactat tgctgacatg
    13261 tacatatcga ggaagttcgg gaagtttttt cagcacttct ataaagcgtt ctttttgcag
    13321 attccaatat gtatcatctg cctgatctgc tgtagaaaaa tgggtaaata aaccttccca
    13381 ttctaataca cgactttctt tgatgaatgc agctgcctct tttacttctt caggtgtaca
    13441 aaatccgata cgacccatcc cagtgtctgc ttttagatga atcgaaagag gcgtctctag
    13501 cttacttttc tctaaaacag cagctgctgc ttgcaaccat tcccgtgtac ctgcagttac
    13561 tgataaatca tgagcaacag ctacagtcag tgcgtcgtaa ggaaccatat tcaagataag
    13621 gatgggctga gtaaatccag cttctctcaa ctcgactcct tcatctaaat ttgaaacaca
    13681 aaagcccgaa gctccacctg caactgctgc ctcagctgtt tcaatagctc catgaccgta
    13741 tccgttcgct tttactactg caaacaattc ttttccttgc ggaagtcttg caacttcatt
    13801 tgctacattt tcagttatag cttttttatg tatcactgct ttcgttgggc ggtgccaagc
    13861 gacaaccatc gtttttcctt ctttctagtc ttccaaaata atttgtgcaa aagctgtttc
    13921 atttgtatga gtaatactga cccatacatt gccttcatga ggtgaacgcg tcacaacagg
    13981 ctgaccattt tcatttttta aaatctcgac atcttgaaag gtaacttttc cgatcccagt
    14041 tccccaagct ttagagaaag cctctttgca agcgtaacgc ccgcctaaaa attctacttg
    14101 gcgatgaaaa ggcaaggact ggaatagttt catttcatca gaggtcaaga ttcgtgcaat
    14161 gaattttggt ttttcttcga tcagccgagt gatcctagga agttcgactg catcgatccc
    14221 aattcctttt atcatatgct tttctctttt caataaattt agaacactct cattctacca
    14281 aattataacc attttgccac aaataagtcc acaaataaca aaaatgaaag tttctcttaa
    14341 aaaagagaaa ctttcatttt atgtttaatc gttatttgaa cggattacaa atccgcgttt
    14401 tttatcattg tgacgtttac cgccatcttt ttggctgtta ttatttttgc tataaccgcc
    14461 ttttgatttg tttccacgat aattaccgcc gtcacgacga ttacggttgt ttccgccacc
    14521 acgtttgcca tttttattgt atcctttttt ctgcattggc aatgggcgtt ctggtgtgat
    14581 cttcactggc actgcatcag ctggatcttt tgctgtcgtt tttagcaaaa gtgcaactaa
    14641 atcttgtgca gaatattctt ctaataattt atctgctgtt tgcaggtatt tatctagacc
    14701 attttctgca agttttgttt cgatttgttc aactgcagca cctaattgac ctttgaatgc
    14761 ttctttttcg gttggtggac gtaaagtcgt catccgtttt ttcgtcaagt tttcaatcac
    14821 atgcaagtag tccatttcat ttggtgtaac gaaagtcaca gacataccgc cttttccggc
    14881 acggcctgta cgtccgatac ggtgaacgta gctttctgga tcttgaggga tatcatagtt
    14941 gtacacatga gtgacacctg aaatatctaa tccacgtgca gcaacgtctg tcgctacaag
    15001 gatatctaaa tgaccgctct taaatgaacg caatacgctc attcgttttt gttgagacaa
    15061 atcgccatgg attccttctg cacggtaacc gcgtgcttct aatccgcgtg ccaattcgtc
    15121 tacacggcgt tttgtacgtc cgaagacgat tgttaattca ggtgtttgaa catcaaacaa
    15181 gcgagtcatg atatcgaatt tttcgtattc ttttgcgcgg acatagtatt gatcgatcaa
    15241 gtcagctgtc atttctttcg ctttgatctt cacatgatgt ggatttttca tgaatttaac
    15301 gccaatattc ttgatagctg gcggcatcgt tgctgagaaa agtaatgttt gtctttgatc
    15361 aggaacttgt gaaatgattt tttcgatatc ttccaagaag cccatattca acatttcatc
    15421 tgcttcatcc aaaactaatg tttgaacggt tccaagtttc aatgtgtggc ggttaatgtg
    15481 gtcaagcata cgtcctggtg tacccacaac gatatgtgga cgatctttca agccacggat
    15541 ctgacggcca atatctgctc cgccgtaaac ggcttgtaca cgtacttttt tgtcgcgccc
    15601 taaacgatat aattcttctt gtgtttggat agctaattca cgtgttggtg cgataactaa
    15661 accttgtaat tcgtgacgat ctggatcgat tttttctaac attggtaatc caaatgcagc
    15721 tgttttccct gtacctgtct gtgcttgtcc aataacgtct tttccagcta atgctagtgg
    15781 aatcgtttct gcttggatag gcgttgcttc ttcaaaacca gcgcgttcga ctgatttcaa
    15841 caattctggt gataattcta gttctttaaa tttcaaatga atcctcctat atggttgtta
    15901 actgaggatg tagctttttt gctaccccgt cgatttgttc ggtcaaagtg tattgtttct
    15961 ttttgacagt ggccacgcac gtttttatcc attcttagcc cctgtggcac caccgaaaaa
    16021 tcactttgcg aagtttaggc attagaaaag ccaaacgggt cgcgttcagc tttatcatta
    16081 ttatgacatc tggcttcaac aagttgtttc tatggcaaaa ccagtccaat ttctcttcat
    16141 ctttcggcaa taggttattc taacatagtt tttcgttttc tgcaagttta cagattttta
    16201 tttcatttgc tgaagttgtt ctaccacttc aaataagccc atgctgttgc tgccttttag
    16261 cataatacta tctgttgctg caagattttg tttgatagca tcaatcaatt tattcttttc
    16321 tttttcaaaa tagaacacag gtagttgggg gtatttttgg ttcaattctt cttttagtgc
    16381 atgcatttgt tccccataaa ggaaaatcat ggcgaatttc tcaggatcga tatgttcact
    16441 catttgcgca tgcatattta aagactcttt ccctaattcc agcatatctg ctaacacagc
    16501 gattctgcgt ccttttgttg gcagattttt aaaagtatct aataccagtc ccatggctgt
    16561 tggatttgca ttgtagacat cgctcaaaat agctgcacca tttcctgccg ttagccattc
    16621 ggttctgttt tgagtgatag aaacatgggc gagcccttgg cgtatctcag gtatggacag
    16681 tccaaagaag cgcccgatcg tatacgcaat caaagcattc gttacattat aacttccagg
    16741 cagcgggatc gtaaatgttt ctccttctac tacaaaatcg gtttgtgctt ttccttttgc
    16801 tgtcacttcc gcatgaacat cgccatttcc aataccgaat gttgtgactg tttgtactaa
    16861 tgttgccgtt aaaggtgtca gcaacggttc atctgcgggc acaacgagta atccgtctga
    16921 tacaagtccg tcagtgattt ccattttggc tttagcgatt ccttctcgcg acccaagatt
    16981 ttctatgtgt gcttcaccga tcattgtgat tgctgcagct tttggttgag ccataagtga
    17041 aagttccgtg atttcattgg cgtgatccat gcccatttcc aaaacgatct tttctgtatc
    17101 ttggggcatg tgcaaaatcg tgtaaggaag accaatatta ttgttgtaat ttccttgcgt
    17161 cttatatgtt ttgtattttt cagacaagac agacgcggtt agatctttcg tggtggtttt
    17221 accattgctt cctgtaattg caacgacttc tgcgcctact ttttccaagt aataggttgc
    17281 caattgctgc atggctttca aaggatctgc tacaggaata actggaaaat tttttggagc
    17341 ttgttcaaca ggcaagctcc aaaatgaagc agatgctccg tttgtgatcg cttgctggat
    17401 aaattcatgt ccatctcgcg taccagcaag aggaacgaat aaacttcctt cggttatctt
    17461 ccggctgtca aattcgacat tggtaatctt tgtcagtgca gagcattcgc tgcccacggc
    17521 ttgtgcaatt tcttgtattg ttagattcat tgagatctct cctaaaaaag gttgtgaaaa
    17581 aagcgtttgg cctaaacggc gggttcgcat gactctcact tccaagtaaa tttctctatt
    17641 cgtatttaga agctagaatg aacgcggtta cgcaatcact ccagcctctt ctttatttct
    17701 ctttattcat ttttttcaaa aaaagattga cgctgatggt atcgattcat tcctaactgg
    17761 atcagttctt caatcaaatc accgtatttc aagcccatat tttcccataa gagtgggtac
    17821 atactgaact ccgtaaatcc tggcatagag tttaattcat tcaggaataa ttcattttta
    17881 tttgtcaaaa agaaatcgca ccggctcaat ccgcttccac ctaacatcgt gtaagctaac
    17941 ttcgcgtact cttgcgcttt ttgataaact tcttctggca cttcggctgg aatctgcatt
    18001 tcgattttat tattgatata ttttgcttca taagcataga atgctacgtc ttttacgact
    18061 tcaccaggca aagtcgtccg aacgtcttca tttcctaata cagcaacttc gatttcgcgc
    18121 gcttcaattc cttgttcaac gattgctcga gaatcatact gataggctgt tgctaaagca
    18181 ttttgcagct cttctcggtt ttctgctttt gtaatgccga cactagaacc catattcgcc
    18241 ggtttgacaa acatcggata aagcaaagaa ccttcacatt gatcaaatac ttttttagga
    18301 ttttctttcc attgattctt aagtactggt acataaggaa cttgcggcac accagcagct
    18361 tgtaaaatat acttggtcat gattttatcc atggcacatg cactggtcaa tacgcctgcg
    18421 ccgacataag gcatattcaa tgtctctaag aagccttgga tcgttccatc ttccccgttt
    18481 ggcccatgta aaactggaaa aacgatggct ccttcttctt tgatttcgcc cggattgatc
    18541 acttttcctg taaagccttc ctctgtctgt ccacttgggt cccatgaaag atgcaagaca
    18601 tctttgctgg caggtttttc tgttagtaat ggacctttga cccattgtcc ttcttttgta
    18661 ataaatacga gttgaacttg gtaataatta taataaatgg catttaaaac tgaaaatgcg
    18721 gaaagaatgg acacttcatg ctctgcgctg cgtccgccat atagtaaagt aatcttcaaa
    18781 agattgtcct cctgtattct aaatcgttca gtgatttact ctcatatttt agcacaaaac
    18841 aaaaataaac gaataactta tttataaaaa aacgagccag cttctaaaag aacgagcgtc
    18901 atttattttt tgtcagctag attatttgtc ccgtttttta taaaaagtta tgataaagaa
    18961 aaggagggat gatgatggcg caaacaaatc cacgcagccg cttggcagaa atcattcgag
    19021 tgttcatcaa ttacaatgta gtgccaaact ttgtacagca aaaaaatccc gaacaggtaa
    19081 aaaaagcctt tgaagaacta ggccccacct tcatcaagat aggacagatg ctttctgttc
    19141 gagaagattt gctttcttct gccttcactc aaacattcaa aacattacaa gatagtgtac
    19201 ctagcgacac attttcaacg gtcaaaaaga cgatcgaaac agaactttct ctttcattat
    19261 cagatatatt cgatgatttt tcaaaatcgc cttttgcctc tgcttctatg gggcaggctc
    19321 atcgtgccaa gctgaagaac ggtgacgcgg tagtcgttaa gatccaacac cctaacatcg
    19381 ccgaagagat ccgacttgat cttcaactat ttgaacgagc gatccctttg atcaaataca
    19441 ttcctgaaac tagcgtagtt gatctaaaag gggtactcca agaagtaaaa cgttccttga
    19501 tcaatgaaat ggacttctta aaagaaagtc aaaatggcga acaattctat caaaagaaca
    19561 atggctggaa agagatccgc agccccaaga tttatgacgc tttttgttcg aaaaaagtga
    19621 tcgtgatgga agaaatgtct ggtaaaaact tgaatcattt aatgaacgcc gaaaacaaaa
    19681 ctgaaacttt tatcactgga attcaaaaca agcagctgaa acaagaagtt gcaaagcttt
    19741 tagttgagaa ctttatgaaa caggtgtttg atgatggttt tttccatgct gatcctcatc
    19801 cagggaatct gctattccat gtactaacaa aagaagaaca gacacaagct agccgaaaaa
    19861 ctgaaacagt ccatgaaaaa gagttcggtt cctttgcttt tcgagcctcc acttctgcag
    19921 aagaccctgt tgcgccatat accatcaact acatcgattt tggtatgatg gggcatcttt
    19981 ctgcaggact taggcaaaaa ctcacacaag ccgttttagc gctgtatacg aaagatgctt
    20041 atcgaatcga aaaagcggtc cttcgacttt gtcagcaaga aggctcgttt gatgaaagtc
    20101 ggttccacca agaactgaca agttttcttg aacagtatta tgattctcct attgatgaaa
    20161 tcaacttgca agaagtattc acacatgtcg tgacgatttg tcatcaaaat aatctgcagt
    20221 tcgatcgtga tatcacgctt ttgctgaaag catttgggac attagaaggg gtgatccgcg
    20281 tcctcgatcc tgaagtttcc ctcatggaag tcgcttcgcc ttttgctcaa cattattttc
    20341 tcactcatct ggatgtagaa gatacattga aacaaagcgg attagactta ttggaaggga
    20401 tgaaggctgc gcctaagatc cctcaacagc tccaccatct attagaaatg tggacttcgg
    20461 gacaaggaaa agtcaatttg gaattgaaaa agcaagacaa attattgagc aggatcgaaa
    20521 gtatgatcaa tcggcttgtt ttcggtatga ttttagctgc attgatcgta gggtcctccc
    20581 tgcttgtcca agcagcacct gtagaaaacg cagaggtcgt ttccttatta gggatattta
    20641 cgtatgctat tgccgcattc gtcattattt ttttggcaat cgatgcattg atccaaatgt
    20701 ataagaagag gaaaaagtag aaaaaggttg tgacagaaag aatcagcttc aagaaataag
    20761 aaggggtttt acataaattg tttctcaaat ttttgtgaaa attcggctta tttttcgaag
    20821 aggctacttc tgaaacaccg agaataaaaa atgtgaaaaa gctgttctgc acccagtaat
    20881 aagaacaatc aaaaagggaa catggaacac atttatcctg tttccctgtt ccctttttga
    20941 tgtattcgag cataaataaa ataccttcgt tacctactat cttctgtact tggtaaacct
    21001 tagtcaattg ccttttttaa cgcttgacga aaagacatat gatctttctc cgtaaagggt
    21061 tttggaccct ttgtccttat gccagctttt cttaactttc cactatgata acgttgttct
    21121 agaagcgtgc cgatattcgc ttcgtcaaat tcttttccag agtgatggaa cactcgcaca
    21181 cccttcggca atacaagtga agctaaacca taatcttgcg tgatcaaaaa gtcattcttc
    21241 ttaaccatac cgacgatttt ataatccgca ctatcagctc cgcggtctac gtagacgatt
    21301 tggacatgat tagcgtattc tttggtcgta taatggtcca cactggtcac gataaccacg
    21361 tcaagaccat aggattctcc taattttatg acatcttctt ttactggaga accatctcca
    21421 tcaatgaata gcctcattct ttttcgcctt cttccataaa tgataaacag ttactaatcc
    21481 gctcagtaaa agaccaacat tgatccattt tgccaagata agcagttgta cactttctat
    21541 cggcactgat tcatggttca gcgtgatcaa taatagatgg attggctctc ccatttcttt
    21601 tgctaaaaca aacaaaagcg tcatcaataa aaactggtgg atcacactcc ctttattttg
    21661 agtagtatac ttgacaacga tccggcgatc cattggaata gctgtatcag tttgataata
    21721 ttccttattt agccagctgc ctgttactac gtgccagaaa ctaagcagaa agacacctat
    21781 cgcaaaacca tttggaatca agaggaccaa taaagaagaa ctcagtccaa gcaattgcat
    21841 agccaatgga gaccatgtta aacgtttcaa aatccatggt ccgactattt ttgctgcaat
    21901 caagcctgct gcataaggca aatacataaa aatcgaaagt ttttctaatc cgtacagtat
    21961 gccaacataa aaactgctaa ataaaaaaag gaaattccct agcattccat ttagaaaagt
    22021 aaacagattt agccagcttg gcaacttcca ttccttcttc tggtgtccta aaacaaacac
    22081 gaacaagatg aacagcagca agaaaccata aatagcaaga tcaaaaagcc tttcatcgaa
    22141 taacaatcgg gcatttctca aaagaaacaa taagccaaag aatatcaaaa ataaaacaag
    22201 ctctcgcgta gctaccagat ttcttttgat gtctttgaaa tccagttcgt aacgcggata
    22261 atgactaacc gtatggtagg ccatgacgta aaaaagtgta taaatagtaa agcttgctgc
    22321 aatctgagtc ggtgcaggca actcaatcgc ttgatacagg agaaatagcc agatagctgc
    22381 aaataagtac tttttcccat ccatattgat aaaaccttgc gtcttttcgt gaaaattgac
    22441 cgtggtatta gcaggtacaa gccatgctgc actcagccct agcaaaacac ttgaaaaata
    22501 aaataaagga aaataaaata cgcctaatat tccaagcaat gaaccagcac caccaatcag
    22561 cagagcgatc atcagcaacg tgtaactatc tagaccaaat cgtagactgt tgactaaaaa
    22621 tagtccagtc atccgaaagg cataaaacag cgtaaatggc aaaatcgtca gccaattatg
    22681 cgagtctgtt agtcccaaaa ataaaagata aggaataaaa ataaccgtgt tacttaagat
    22741 aaagggcgtt gtttgtgtaa aattacgccc aaatcgtttg agtttttcga acatgacaat
    22801 ggctccttaa acagtcttat aactaatctg ctcttcgatt ttagcattaa aggggaaata
    22861 aaccaatttt acagaatata ttcttgtaaa aaaaaataca gaaagaagca taagcttctt
    22921 tctgcatttt tacggtactt gattactcaa gcagacaagc ccttctccac aaaagtcttg
    22981 cccgacaccc ctgcatccgg caggtgataa agatagaaat caattatcct gtgcctccaa
    23041 aatcaattag gagctctgta aaccagagtc cttctcgacc cgtcgcataa atttacttta
    23101 acacagttcc tatgtttatg cgagagcttt tttcatttta taatcgacca tttgaaatcc
    23161 ttgaccgata tctgaaataa gttcttctgt aatctcaaat ccttcatgct tataaacctc
    23221 gattgcttga tgattcccct gattcactcg caaaaagatc tctctttcct ttgtttgcgc
    23281 agcaagttct tcataccagc gaaaaactga agaagtcaat ccttgaccac gtactttatt
    23341 tagcaaatat aatttactta aataaatttt tccatttatc tcttcataag cagtgtaacc
    23401 gacagtcttt tcttcgcttt ttaataaaaa gtaggacaca ccttctgtca gttctttttg
    23461 aatctgtttt tttgactgat aagttttcag catgtaatcc acttgttttt gaccaatgat
    23521 cggcacaaaa gcttccggcc atacttcttg tatgactgcc atcagctcat ccagttcatt
    23581 ttctgttact tttatttttt ccatacaccc acgtcctttt ttacattata aatgaccttg
    23641 cgcttgatgg aataaaaaga gcatgatcat gctatacaca cccaccgacc atggtttcaa
    23701 gaaaatcaca atctgcataa attccctaaa agataatttc gtcaaaccag ctactagaca
    23761 gatcaagtcg tctggcgcaa agggaagcag caaggtaaca actagtactt ttttaatatc
    23821 tttcgttttt cttgtcagca attcatcaaa tttctgatac ttttttggcg ataaaataag
    23881 ctggacaaag gctacgccat agtaacggac aagcaaaaat ccgattgctt ccccaatcac
    23941 taggccaata caactatata aaagcccaaa tccattgcca aacatcagca tgcccgctac
    24001 tgaggagatc cctcccggca aaataggaat gatcacttgg atcacttgca acagaacaaa
    24061 tatcatcact gcatacttgc caaattgctg gataaacgct tgcaaagacg tgctcgatcg
    24121 aaaaatccca tgatgataag cataaagaat caacacaaag aaaaaaaaca gaccaataat
    24181 gggcatgatc tgaagacatt tttgtaaaac tgatcctttt ttagacatct atattcccca
    24241 catctttttt catttattaa aactgcctcc t
//
LOCUS       DAYNVV010000040        23828 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.040, whole genome shotgun sequence.
ACCESSION   DAYNVV010000040 DAYNVV010000000
VERSION     DAYNVV010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23828
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.040"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(54..788)
                     /locus_tag="ACGXWR_001814"
     CDS             complement(54..788)
                     /locus_tag="ACGXWR_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFK0803370.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1115..1525
                     /locus_tag="ACGXWR_001815"
     CDS             1115..1525
                     /locus_tag="ACGXWR_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HFK0803371.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1518..2219
                     /locus_tag="ACGXWR_001816"
     CDS             1518..2219
                     /locus_tag="ACGXWR_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HFK0803372.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2219..3805
                     /locus_tag="ACGXWR_001817"
     CDS             2219..3805
                     /locus_tag="ACGXWR_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0803373.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3824..4045
                     /locus_tag="ACGXWR_001818"
     CDS             3824..4045
                     /locus_tag="ACGXWR_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HFK0803374.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4042..4803
                     /locus_tag="ACGXWR_001819"
     CDS             4042..4803
                     /locus_tag="ACGXWR_001819"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HFK0803375.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5183..5692
                     /locus_tag="ACGXWR_001820"
     CDS             5183..5692
                     /locus_tag="ACGXWR_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFK0803376.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5767..6306)
                     /locus_tag="ACGXWR_001821"
     CDS             complement(5767..6306)
                     /locus_tag="ACGXWR_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HFK0803377.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="ACGXWR_001822"
     CDS             complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="ACGXWR_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HFK0803378.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7319..8170
                     /locus_tag="ACGXWR_001823"
     CDS             7319..8170
                     /locus_tag="ACGXWR_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFK0803379.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8198..8833
                     /locus_tag="ACGXWR_001824"
     CDS             8198..8833
                     /locus_tag="ACGXWR_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HFK0803380.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8853..9626
                     /locus_tag="ACGXWR_001825"
     CDS             8853..9626
                     /locus_tag="ACGXWR_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFK0803381.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10034..10831
                     /locus_tag="ACGXWR_001826"
     CDS             10034..10831
                     /locus_tag="ACGXWR_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HFK0803382.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10809..11222
                     /locus_tag="ACGXWR_001827"
     CDS             10809..11222
                     /locus_tag="ACGXWR_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFK0803383.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11206..13851
                     /gene="mutS"
                     /locus_tag="ACGXWR_001828"
     CDS             11206..13851
                     /gene="mutS"
                     /locus_tag="ACGXWR_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFK0803384.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13869..15977
                     /gene="mutL"
                     /locus_tag="ACGXWR_001829"
     CDS             13869..15977
                     /gene="mutL"
                     /locus_tag="ACGXWR_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HFK0803385.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15999..16559
                     /locus_tag="ACGXWR_001830"
     CDS             15999..16559
                     /locus_tag="ACGXWR_001830"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HFK0803386.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16644..18632)
                     /gene="treP"
                     /locus_tag="ACGXWR_001831"
     CDS             complement(16644..18632)
                     /gene="treP"
                     /locus_tag="ACGXWR_001831"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HFK0803387.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18855..19568
                     /gene="treR"
                     /locus_tag="ACGXWR_001832"
     CDS             18855..19568
                     /gene="treR"
                     /locus_tag="ACGXWR_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HFK0803388.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19645..20091
                     /gene="msrB"
                     /locus_tag="ACGXWR_001833"
     CDS             19645..20091
                     /gene="msrB"
                     /locus_tag="ACGXWR_001833"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HFK0803389.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20261..20863
                     /gene="ruvA"
                     /locus_tag="ACGXWR_001834"
     CDS             20261..20863
                     /gene="ruvA"
                     /locus_tag="ACGXWR_001834"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HFK0803390.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAIEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20876..21877
                     /gene="ruvB"
                     /locus_tag="ACGXWR_001835"
     CDS             20876..21877
                     /gene="ruvB"
                     /locus_tag="ACGXWR_001835"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HFK0803391.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21906..22484
                     /locus_tag="ACGXWR_001836"
     CDS             21906..22484
                     /locus_tag="ACGXWR_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFK0803392.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22536..23018
                     /locus_tag="ACGXWR_001837"
     CDS             22536..23018
                     /locus_tag="ACGXWR_001837"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HFK0803393.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23135..23509
                     /locus_tag="ACGXWR_001838"
     CDS             23135..23509
                     /locus_tag="ACGXWR_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803394.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7782 a         4285 c         5114 g         6647 t
ORIGIN      
        1 taaaaaaact tggtacgcaa tcgctgtacc aagttttttt atttagcttt tgattaagcc
       61 ataaataata atttatataa gaatactgct acgacaccag cacagatagg tgctacaact
      121 ggtacccatg catatcccca ttgagaagaa cctttatgtt tcaatggaag aagtgcgtgt
      181 acaagacgtg gagcaaagtc gcgggctggg tttagtccag gacctgtagg accaccaagt
      241 gaagcaacta atgtccatac aaggaaacca agtgctaagt gagctgtacc aagattatct
      301 tggaagaatg gtgcttttgt aatacctagg gcaccaaaga ataaaacgaa tgaaccaaag
      361 aattcattga cgaaaccatt gaatttagaa ccaacgctgt tgattgttga gaatgtacct
      421 aacacatggt ttacgtcttc tgtttggtcg tagtaaggtt tgtaacaagc tactacgatc
      481 aattgtccaa tcgctgcacc aatcaattgt gcaatgatat aaggaacaac ttcagcccaa
      541 gggaatagac cattagatgc taaagcaatt gtaaatgctg ggttgatgtg gttaccgctg
      601 attccaccaa aaatcattgc tggcatcata accccgaatc catacccgac agcaatcagc
      661 atccagtcac tgccatatcc ttttgtacct tttaaatcta cgtttgctac agcaccgtta
      721 cctagaacga ttagtaatgc tgtaccaatc atttccgccg caagacgggt cattagtgag
      781 taatccataa atacctccaa aagttataaa aatgcaaaaa aaaaagaaac atcaacacga
      841 aaagcatcgg tgcagtgttt cgtgtcggaa ggatttctgc agtcttaaca aatgtgaata
      901 aaaaaatgaa ttccattact tataagaaac cagaccaaca gtaaaactcc aactcttttt
      961 aaaagttctc cacaaatcac caagcttaac tataaatata ccaaaaaaaa aacgtttttt
     1021 ttctcaaaaa ttgtatctta gaaacagcat gttttgaaac tttcagaaaa ggtttgttag
     1081 taaaatgaaa gctatacgta aggagtgttg tttgatgaaa ttttttcaag agtttttcat
     1141 tattattttc ttttctgtat taggagaagg catacggatt tttgctcatt tacctattcc
     1201 tggaagtatc ttaggtattc tttttttatt tttagcattt gaaatgcatc ttgttgatcc
     1261 tgaaaaaatc ggagcaactg gtgatttttt attgaataat ctagccattt tatttgttcc
     1321 tgctggtgta ggtttattgg aatattttga tgatattgct tcgatatggc ctgttttact
     1381 gggagcagtc gtcgtgtgtt ccatcgtcac gatggttgca gcgggaaaaa cggcagaagg
     1441 tgtagaagct ttgctgggct atgtccgtaa gaaaaaagca gaaagggtat ctgtaaacga
     1501 aatggaggag aatcaaattg actgagtttt ttgtgaatcc attatttggc ttaagtttga
     1561 ctttaggagt gtacgtatta tctgacaaat ttttgcggaa atataaactg cctgttttga
     1621 atcctctcgt attatcgatt gttgttatta tcttattttt gcatttttct gggatcagct
     1681 ataaagacta taatatcggg ggcaattttt tgactatgct gattactcct gcgacagtgg
     1741 cacttgccat ccctctttat aaaaacttcc gtttactgaa agagaatttt tatcctgtaa
     1801 tggctgcgat tttagcagga atagtcgcaa attgcttggt tagtgtaggg ttcggttact
     1861 tcttctctct tcataaagag atggtgatct cattactacc taaatctgta acgacggcta
     1921 tttctgtcga tttatctcat acgatgggcg gggtgaatgc cgtgacactt gctattgttg
     1981 tctctacagg tatttttggt tcgctgatcg ccactcatat tttccgccta ttcaagatcg
     2041 aaagtccagt tgctcgcggt gtggcgttag gaagtacttc tcatgctatt ggtacagcaa
     2101 aagcaatcga gattggtgaa atagaaggaa tcatttccgg acttgcgata tgcgtcaacg
     2161 gaatattgac cgttttattg ctaccgttat tctttcagcc ttttgctggc ttgttttgat
     2221 gcgaaaacca ctattttatg ctacaataac caaaacgttc gagcataaaa aaggagggaa
     2281 agacgtgtat ttgtcttccg agtatcttaa acaatttgat aaagatctat attataagat
     2341 tctcctccta gaaagttttg aggatcaagc ttggcatacc gctgcacaat tagcgcaagt
     2401 tgttcagctg gatgcccgca gcgtgtcgaa atacctgaac gagctgtcta aaaactatca
     2461 gcagtttagc ggtaagacac accctttgtt tacaaaaaat caccgttctg gttataactt
     2521 ttatgatacg ctcgattcaa ttgaacatga gcgttttttg atctatctcg tgcaaagtac
     2581 gctgaaattc cagttgctgc acgacatttt ttttgaagaa ttccatacaa tgtaccaatt
     2641 tgcgcaaaag cattacatta gtgaatctac tgctcatcga aaaatcaatg aatggaaaca
     2701 gcaactgcaa acttacggaa ttcggctgca acgaggtaca tatatcgctc aaggcgaaga
     2761 agaaatcatt cgactttact tgcatatgac attctggcag ttgtttcgag ggaaaatctg
     2821 gccatttgaa acgatttctc aaatggacgt aaagaatatg gcagaacata tcatggcttt
     2881 ttttaatgtt cgtctgaacg agatcaaaaa aagacgattg gaatatatgc taggtgcctt
     2941 ttttttaaga aaatcacaga agcattatgt tgtattgaat gagaaaaaaa gacggctgat
     3001 ttctgacaat ctgttgttcc agcgattttg ccaggtcatg gagccggtat ttcctaatta
     3061 ttttcaagta gaagacgagt taggcgcatt atttcttgta ctgatgactc gtgaagaata
     3121 ttatagtgat cctaagatac ggaagaaaat ttttgatttt catcaacaag caaaaacacc
     3181 gccctttaca gccctttcag aagcaaaagc cgctctttct ctttatcagg aagagcaggg
     3241 gctgccagca gaaaatctaa ccttcgaggc agaaaactat ttattcagca gtcatttttt
     3301 cgcctatctt tttcctaatg cgaaagaaac gattgatggc aatagtagtg attttattaa
     3361 tcatttagtt attgaaaaca aggaattgaa acaatggctc gtacattttt ttgaaagtag
     3421 acacaaacat cccaatcatc tggcatttaa aaatcatgcg tttttgatgg ggcggtatct
     3481 gactgtgttt aaaacattag gagcctttac tccacagctt ccaaagatca cgatcctttt
     3541 aatgacagat ttcccattat ttgaagagca actgttagag gagggattac ggacattttt
     3601 ccgtaatgag tatcagctga tttttctgcc aacagattat cgggggagag aagttgatct
     3661 tctgatttcg acaagtaaag tccaccgcaa accatgggcg gatcttgact attttattgt
     3721 gactgaagaa ctaaaattaa ttgattacat ccaactatct caaaaatttg aaatgattca
     3781 aaaacaaaaa ctattaaaac aataacaaag aaggagaaaa aagatgacat ttgaagaaat
     3841 tttaccagaa ttgaaaaaag gtgcaaagat tattcgtaaa ggatggagtg gatttgaact
     3901 ttatgttgtt ctcgtatccg atgatgaatt tgatggctgt ccggtgacgc cgtacttatt
     3961 gatcaaaaca agtgacgaag gtttttccag cttcgctcct acagtttgtg atattttagc
     4021 agatgattgg gcgatcgtag aatgaaaaac cagtatccag atctagctaa acaggttgta
     4081 tttatcacag gagctgcttc tggaattggt gctgcgcaag cccgagcgtt tcttgaacaa
     4141 gatgcttttg tatttggatt agatcaaaag ttcggtaaaa tggaagaaat ttctttgcga
     4201 tttcctgaaa cttttgccta cgcactaggt gatgttcgac aaatgaaaga actccaacaa
     4261 gcggtatcga aatgccaaaa tcattttggt gaagttacga ttttactgaa tacagcgggg
     4321 atattggatg cctacaaacc cttgatggaa actgacgaat cgctgtggga tctgatttat
     4381 gagacgaatg tgaaaagcat gtatcagctg acaaaaatca tccttcctga tatgatccgc
     4441 caaaaaagcg gaacgatcat caatatggct tcgattgctg gcttgattgc tggtggaggt
     4501 gggatcgctt atacaagcgc gaaacatgcg attgtcggat ttaccaaaca actcgctctg
     4561 gattacgcag gacagggtat ccgagtaaaa ggaattgctc caggagccat ccaaacacca
     4621 atgaatgcgg ctgattttga agggaaaggt gagatggcag agtgggtggc aaatgaaaca
     4681 ccagtcaagc gatgggcaca gccggaagaa gtagctgagc tgacgttatt tcttgcctct
     4741 cctcaagcaa gctacataca aggaacgatc atcccaatcg acggcggatg gttgttaaaa
     4801 taaccttgtg tttttttcaa gcttctgtat gataaaacta aagagagaaa caacggttga
     4861 tgataaaaaa agtcgatgac tgttcccgac attcgatgcc gaacagccag ttcaaaaaat
     4921 tctttttaat aatcgttaat attcgaaact aagcggcttt tcacgacctc ttgatataaa
     4981 cgatattcaa aagcttgcaa ctgcggtaac aagtccagcc aaatgaaaaa tataaggagc
     5041 tatttttatt tgaccattct tattacttgt tgcagggcag ctttttcact accttctgcg
     5101 acacttcagt tggaattttc ttcccatcct ttggtcgcgg tcattaccaa gataaaatta
     5161 tcttgcaaag gagaaataga acatggaaaa aaataatacc cgttcagcca aacgctggac
     5221 aacgacagat gtgactcgga tggcgctagt cactggttta tatgtggcag tgacgctggt
     5281 tttgtctgtc tttagctttg gagtgattca gattcgtctc tcggagatgt tcaactatct
     5341 gtccttgtat aacaaaagat acatcgtcgc ggtaacagcg ggagtagctt tggctaatat
     5401 tgcttctcct cttggactga tagatgttgc agtaggaagc gtcagcacgc tgcttgtatt
     5461 gcttatcaac tataaaatca ctagtcgcat caaaaacatg aaaatcaaaa tggccgtgac
     5521 agcatgcgta tttgcttttt ccatgtttac agtagctggt cagctaacga ttttatatca
     5581 actacctttt ttcttgaatt ggtgggtgat tgctttagga gaattggcat caatgattgt
     5641 cggtgggata attatttatt ggatcggtaa aaaagtggat ttgtcaaaat aaagatctgt
     5701 ttaatttaaa atagggcagc atggaagaga ctgaatgttg agtcttcttc catgctgctt
     5761 ttttgattaa tttgtatgaa gaaatcgatt tagccgtttt ttcatcaaga taccgatata
     5821 agctgctcca gttgccttga ttgcttccgg cagtaaaaac ggcagtagtc cactggcaaa
     5881 tgcagttgta aaagtaagat caccacttat tttcagccag atcgttccgc agatcaatgc
     5941 agcaagagag cccattagat tggcaaagat tgcatataag taatgagcat ccgttctttc
     6001 gatcatccaa ccagttatcc acgtttgtaa gagaaatcca atcaaatatc cgccagttgg
     6061 cccaaataaa acagctatac ctccagtcat ccctgaaaat acaggaagac caatcaagcc
     6121 aagtaaaaga taaactccaa cagatatcaa tcctagtttt cttccgagaa aagttgctgt
     6181 taatccaata gcaaatgttt gccctgtcaa aggaaccaaa ccaaaaggaa tggtcatctg
     6241 agaaaggaca gaaataatcg cggcaaattc cgcagcaagt atcaattctt tcaatgttcg
     6301 gttcataacg ccctcttttc gttaacttaa tatttttatt tggttaacga aattgtaaaa
     6361 caaagtgatt actttgtaaa tagaaaatat aaaaaaagac cagctatcca atagatagcg
     6421 gtctttttca agaaagcttt tgaaattata agctttggtt gtagtattca acgacaagag
     6481 cttcgtcgat ttctggatat agttcgtcac gttctggtaa acgagtcaat gaaccttcca
     6541 atttttcagc gtcaaagctt acgaatgctg ggcgtccaac agttgcttct acagcttctt
     6601 ttactgttac gatgttttgt gatttttcac gaactgagat cacttgaccc acttctacgt
     6661 ggtatgaagg gatatcaacg cgtttgccat caactaaaat gtgaccatgg ttaactaatt
     6721 gacgtgcttg acgacgagtc gttgcaagtc ctaaacggta aacaacattg tctaaacgtt
     6781 gttctagtaa gatcatgaag ttaacaccat gtttaccttc tttgattttg ctagctttta
     6841 cgaacaagtt acggaattga cgttcgttca ttccgtacat gtgacgaagt ttttgttttt
     6901 cagttaattg catgccgtat tctgattgtt tgccacggct attaggtcca tgttgacctg
     6961 gtgcgtaagg gcgacgtgct aattcttttc ctgtgcctga caatgagatg cctaagcgac
     7021 gagaaatttt ccatgatggt cctgtataac gagacattaa aatttcctcc aatgaatata
     7081 agtttttgga gtaaaataat ccgttgaaaa attcataatc atatagtttg ttcttcaatc
     7141 ttcacctttg cagccgcggt tacacaatcg aacccgagac ggggcaacaa actagggatg
     7201 agttattatt tttctgctgc attattttac acaaattaca gtatatgata gatcatccac
     7261 gaatgtcaag ataattagta cataaaaacg ctttacaaac ctaggctgtc tttataaaat
     7321 gagagggtat gtgcaaatgg aaaaaagcga aggaagttta aggagaaaat caatgaatcc
     7381 ggtatcacca ttatttgaga aaatcgatgc ttcaattgaa aagaaggcga atctttttga
     7441 aaacagcttt tcacgttacg ctgttcgagc ggttctcgcc tgtttgtttt tgactttagg
     7501 aacggctgtg gcatttgcga tcgcgatgaa gggggaagat atcgcgcatg gtctaggaaa
     7561 gattttatac gcatttatgt tcagctgggg tctggtcatg attctataca tgaacgccga
     7621 attaggaaca tcgaatatgc tttatatgac cgtgggtgtt tttcggcaga gacttgcttt
     7681 aagtaaggca gccaagattc tatttgcctg tatttttttc aatatgattg gcggtatatt
     7741 atgtggattt ctaatttcta tgactacgcc atttcaagat ttaacgttgg acaactttat
     7801 gttagaatca atagcagtaa aactagcaaa accttcagca acgattttgg tggaagggat
     7861 gtttgcgaat atcgttgtca ataccgctgt actgatcagc atgcggatga aagaggatgt
     7921 cggaaaagtg atcacagtcg tattcatcat tttcattttt gcttttttag gatatgaaca
     7981 cgtgatagcg aattttcctg cctttacgct tacttacttt gcttctcacg gacagatgga
     8041 tggaatgaca gtcagcaatg tgttacataa tttgtttttt gctttggcag gaaattatat
     8101 tggtggcggt ttagtaatgg gactgggata tgcttggctg aatcagtcaa aatcatccta
     8161 tgtggactaa aaagtcgttc attaaagggg aagtgccatg gaagttttag tttttccaaa
     8221 aaatgaggaa aaagcgttac aaatggaaaa gtacatgaaa aatctttttt cctttgctgg
     8281 agtacctaag ccggaacgcg ctcttttaca acaaccgtta ctggatgaga gcaaaaattt
     8341 atctatttct gaagttttag cttttgttca ttattattat gaacaaatcg aaagagagta
     8401 tcagtatgta gcgatcgatt tagtccagaa aaacatcaaa cggcttacat ttgaagactt
     8461 agtcgtattg ttgccactag ttcagaaaaa agaatggtgg gacagcatcg actcttggag
     8521 aaaagtatac agcacatggt gtaaagccta cccagagcag cgtgaagaag tctttcaatt
     8581 gtttgaaaaa aaggaagatt tttggctacg tcgaatagca atcacgttgc aattaggtta
     8641 taaacagcaa acagacacag gactattgat ccgagcaata gacgaagatc gtcaaacaaa
     8701 ggaattcttt atccaaaaag caattggttg ggcattacgc gattatagta agaccgatgc
     8761 cgattgggta aaaagacagc tgacaacaga tttgagtaag ttagctgttc gagaggcaag
     8821 taagtattta taagaaagcg agacgacaag agatgagacg caaattattt gcttttgata
     8881 ttgatggaac gttgttagat tcaaacaaac aagctttaga tagcacaaga gaagcattgg
     8941 aaaaattacg caaagccggt catctggtca cgattgctac agggcggagc cgatttcatg
     9001 cgcaagagat cattcgcgat cttgatttta cgaactacat tttatgtaat ggagcggccg
     9061 gttttttaga ccatgaacaa gtatataaga atttactaga tcgcgaccag ttggatgcgt
     9121 tcgttcaaga agcgcatcat gagcagatcg atacagcttt tgtcagctta gacaatatca
     9181 agcgttcttc ttccaatgat gtaacggtga tggaagaagc gatgcattct ttcggtgctg
     9241 tcttgcctga attagatcag ttttttgcag aggaacaaga aatataccaa gcgttagcat
     9301 ttttcgatca aacatatgat gggaagttct cttcatatga taaaattcga tttgtccgct
     9361 ggcatgagaa cagtgtagat gtcgtaccta aaaatggttc taaagcagcg acaattctgc
     9421 acttagcaga acaagtaggc atccctcatg aagacatcat cagctttggc gatggacaaa
     9481 acgaccgtga aatgttgcgc atgtcaggaa ttgggatagc tatggggaat gctgtgccag
     9541 aagtacaagc agaagctaag atggtcactg atacaaacga tcaggatgga atttggaagg
     9601 cattgaaaga gttaagcgtg atttaaaaga ggttgtgaaa aagctgttct gcatcaagta
     9661 ataagcccag ccaaacaaaa atagctcctc ctatttttcg tttttctggg cttattaccg
     9721 cagatgcaag ctttcgaaca ccgtttaagg aagaggtcgt gacagaagtg gtcagtttca
     9781 agaaataaga agggatttac gaaaattgct tctcaaattt ttgtaaaatt acggcttatt
     9841 tctgaagaag tagatgaaac aacgtttatt cgggaaatgg gactgtgaca agatgtttgt
     9901 catagtccca tttttttatt ttatttttca aaactaagaa ataccaggaa agagttcctt
     9961 ttgtttgacc ttttctttct tattgaaaac aactataata tagagtgatg ttaaaagaga
    10021 agaggaattt agtgtgcggg tattgtttat tggtgatgta gtaggttcaa tgggacgaga
    10081 gatgattact gaatatcttc ctagattgaa gaagaagtac cgtccgcaag taacgattgt
    10141 aaatggtgag aatgccgctt ctggacgtgg aatcacagaa aaaatctata aaaaattttt
    10201 gcaagacggc gtagatgtcg tgacgatggg gaatcatacg tgggacaacc gcggaatctt
    10261 tgagtttgta aatgaagcta aaaagatggt tcgtccggca aattttccgg aagggacgcc
    10321 tggacaaggg atggtctttg tcaaagtgaa ccaagtcgaa ctggcagtga tcaacatgca
    10381 ggctcgttct tttatggtgg acttggatga tccttttcgt aaaatgaatg agctggtaga
    10441 agaagccaga aaacgtacgc cgatcatttt tgtagatttt catggagaaa caacaagtga
    10501 aaaacaagca atgggctggt ttttagatgg gaaagtttca gcagtggtcg gtacacatac
    10561 acacgttcag acaaatgatg cgcgaatttt gccaagagga acagcgtatc tgacagacgt
    10621 tgggatgaca ggtccctatg atggtatttt gggtatgcgc agagaacctg taatcgaaaa
    10681 gtttctgact gcattaccaa aacgttttga agttgtggaa caaggccgat cgattttaag
    10741 cggctgtatc ttggaattgg atgatacgac aggtcatgca aaagaaatcc agctgattca
    10801 gatcaacgat gatcgaccgt tcatggagta gaaagagagg cagttttttg cagcaggagc
    10861 cggaaattca aaaagaagta aggaaactga caaaactttt aagagagaat gaaacgatca
    10921 ttcgctacaa agaacttgaa gaaaagatcc agcaaaacca gtatttagct gagttgagag
    10981 aaaaaatcaa acaagcgcaa aaagatgctg ttcattttgc ccactatgac aaaccagcag
    11041 cagaaaaaga agcaatcaaa caagcggatc aattcatgca agaatttgat cagcatccgc
    11101 ttgttgtagc ttatagaaaa cagctgttgg aagcagatga tctgcttcat catttaacaa
    11161 ctatgataca agaagaaatc aatggacaaa tagaggagga aaaacatgcc tcaaaaaact
    11221 aaaaatactc ctatgatgga acaatatcta agcatcaagg cccaatacca agatgctttt
    11281 ttgttctatc gtttaggaga cttttatgaa ctattttacg aagatgcgat caaagcgtca
    11341 cagcttttgg aattaacgtt gacgagcaga aatcgaaatg cagaagaacc tattcctatg
    11401 tgcggtgtac ctcaccatgc agcacaagga tatatcgatg ccttgattga aaaaggctat
    11461 aaagtagcga tttgcgagca ggtagaagat ccaaagacga ctaaagggat ggtcaagcgc
    11521 gaagtgatcc agctagtcac tcctggtaca gtcatggaca gcaaaggatt gtcggcaaaa
    11581 gacaacaatt ttttaacagc tgtagttagt caaggaaatg aatttggctt tgcttatgcc
    11641 gatttaagta cgggagaatt gaagacggct cggttgcatg atgaagaagc tgttttaaat
    11701 gaagcctctg cattgcagac aaaagaactc gtattaggca gtgagatcac tgataccctt
    11761 cgtgaacagc taagcgggcg tttagggcta gtcttttctc aacaaaatga gatggaagaa
    11821 aacgcggaat ttagcttttt gacaagcgaa ctagtcgatc cgctggaaaa agaagcaacc
    11881 ggcaaactat tgacttattt atcggtgaca caaaagcgga gtttagctca tatccaaaaa
    11941 gcagtagaat accaaccaga tcattttttg aaaatggatt attattcaaa attcaaccta
    12001 gaattaagcc aatctattcg gactgggaaa aagcacggca ctcttctatg gttgttagat
    12061 gaaacaaaaa cagcaatggg tggccgttta ctaaaacaat ggctagaccg tccgcttatc
    12121 caggcaaaac aaattaaagc aagacaagaa atggtcgctt ctttgctaga cagctatttt
    12181 gaacgtatcg atttgcagtc agcattaacg aaagtctatg atctggaacg cctagcaggt
    12241 cgagtagctt tcggtaatgt caatgggcga gacttgatcc agctgaaaac ttctttagaa
    12301 caagtgccaa tgatcagagg gttgattgaa ggaatcgatc aaggtcaatg gcaaagtctg
    12361 ctttcagaaa tgcagccgat ggaccatctc gtccaattga tcgaccaagc tatccaagat
    12421 gatccgccgt tacaaataac ggaaggaaac atcatcaaag atggattcaa tgagcagctc
    12481 gatatgtacc gttctgctat gagaaacgga aagaaatggt tggcagaact tgaagcaaaa
    12541 gagcgtcaag aaacaggaat caagaactta aaaatcggat ttaaccgcgt tttcggttat
    12601 tatatagaaa ttacaaaagc aaatcttgga aatgcagaac tggagaagta tgaacgaaaa
    12661 caaactttag caaatgcaga gcgtttcatc acaccagaac taaaagaatt ggagacacaa
    12721 atcctcgaag cagaagaaaa atctgttgat ttagaatatc agttgttttt agctgtgaga
    12781 gaagaagtca aaaaggctat ccagccgcta caagtacttg caaaagcaat cagtgcagta
    12841 gatgtgctac aaagttttgc aacgatcagc gaacgctatc agtatgttcg gccagaactt
    12901 gtcagtgaca agcatcagct tctgatcaaa gacggacgac atcctgtagt agaaaaagta
    12961 ttaggacatc aggaatatat ccctaacagc gtagaaatgg cagaagacga aatgatcttg
    13021 ctgattacag gaccgaatat gtctggtaaa agtacgtata tgcgacagtt ggcattaact
    13081 gttctgatgg cgcaaatggg ctgtttcgtt ccggcaaaac aagcagtttt acctattttt
    13141 gatcggattt ttacccgaat tggtgcaagt gacgacttaa ttgctggaca aagtactttt
    13201 atggtagaga tgatggaagc caatcaagcc ctgcgttatg ctacgccaaa cagtttgatt
    13261 ttgtttgacg aactagggcg aggaacagca acctatgacg gaatggcgtt ggcccaagca
    13321 atcatcgaat atatccatcg tcatgtacaa gcaaaaacac tcttttctac tcattatcat
    13381 gaactgacgg tacttgagaa agaacttccg cagcttaaaa atgtccatgt tggagccgtt
    13441 gaaaaagacg gagaagttgt cttcttgcat aaaatgatgg atggacctgc ggataaaagc
    13501 tacggcatac atgtggcaaa gatcgcagga ttgccttcca atctactaga acgagcagca
    13561 gatatcctgc atacgctaga aaatggcgat aacggacacc atactgttcc agctgaagta
    13621 gaagagaaaa ctaaaacagc caaacaggag caaataaaac cacctgcaga aaaagtaaat
    13681 caagaccata tacaagaccg tgtaaaagaa gaaaaccaac agctttcttt attcagtgaa
    13741 ttatccgaaa atgaaacaga agtcattgaa tcactgaagc aaataaattt actagaaatg
    13801 acgccaatgg atgcactaaa cacattatat gaattacaaa aacaactgta ggaagaaggc
    13861 ggatatcgat ggccaaaatc caagaattat ctgaacgttt agctaatcag atcgctgcgg
    13921 gagaagtagt ggagcgacca gcttccgttg tgaaagaatt agtggaaaat gcaattgacg
    13981 ccggcagtac tcagattgat atcttagttg aagaagcggg actgcggacg atccaagtga
    14041 ttgataacgg agaaggcatt ttggcagacg acgtagagaa tgccttcaag cggcatgcga
    14101 caagtaagat ccataatcgc gacgatcttt ttcgcatacg aacgctgggc tttcgagggg
    14161 aagctttgcc aagtattgcc tctgtttctg aaatgactct ggaaacggcg aatcaggaag
    14221 aaaaacaagg cacctatctg tcgctgaaag gcggagaagt tattgagcat cgaccagcac
    14281 cactgcgtca aggaacgaag attaccgtca gcaatctgtt tttcaatacg ccagcccgct
    14341 tgaaatacgt gaaaacactg cacacagaat tagcgaacat cggggacatc gtcaatcgac
    14401 tggcattgag tcatccatcg attgcttttc gtttagtaca tgatggaaac aaaatgctgg
    14461 caactgctgg aaatggcgat ctgaaacaaa caattgcggg aatctacgga ttatctaccg
    14521 caaaaaaaat gctgaaaatc gaaggaaaag atctagattt tgagttattt ggctatgttt
    14581 cattgcctga ggtgactcgt gccagtagga attacttatc gacgatcatc aatggacgtt
    14641 ttatcaagaa cttttccttg aataaagcaa tcgttgcagg ttatgggtca aaattaatgg
    14701 tcggtcgttt ccctattgct gtattggaaa tcaaaatgga cccgctttta gtagatgtaa
    14761 atgttcatcc gacgaagcag gaagtccggc tgtcgaagga aaaagaacta acagagctaa
    14821 ttagtaacgc cattcaaaaa gcattgtctc aagaaaatct gattccaagt gcagcggata
    14881 atctacggtt taagaaaaaa gtacctgatc agcctaaaac agaacaaatc gaaatcgatt
    14941 tgtcctacgc ttttgaagaa gaaaaaccta aaaagccaag tagtttgaat tttgatcgag
    15001 agacaggtac ctttttcgta gaagaactaa agaacacatt tgttgacaga attgttgata
    15061 agtctgtgga aaatgttgaa aactattctg gtttttctga agaaaacacc acttatccag
    15121 aaaaaacagc gaaaacggtg gataagtttg gtgaaaatgt tgataacttt gtagaaaaaa
    15181 cagtggaaaa atctgaaaag aaagaatttc ccattgtgga taacatggag aaaacaaatg
    15241 aagaacaagc agataaatcc gtagaagagg atgaaaagat ttacgaggaa gaattgacac
    15301 tccatcctga atttgatttc actcaaggaa acgacaaaac attagaacaa gccatcaaga
    15361 aattagaaac ggaaaaacca gtacaacgtt ttcctcagtt ggaatatttt ggacagatgc
    15421 acggaacgta tctttttgcc caaagtagcg atgggttgta catcattgat cagcatgctg
    15481 cccaagagcg cattaagtat gaatatttcc gggaaaaaat tggggaagta tctgatgatc
    15541 tgcaagaatt gcttgttcca tttgtgttag actatccaaa cagtgatgct ttgaaattaa
    15601 aagagcaaaa acacttgcta gaagatgcag ggatttattt agaagaattt ggtcaaaaca
    15661 gctttattgt acgggcccat cctacttggt atcccaatgg agaagaagaa tcgattattc
    15721 gggagatgat cgatatgctg ctgacaactg gaagtgtgag tgtaaaaaaa ttccgtgaag
    15781 caacagcaat catgatgagt tgcaaacgat cgattaaagc caaccattat ttgaatgaag
    15841 cacaagcacg tgtgctgctg aaggatctgg cacgatgcga aaatcctttc aattgtcccc
    15901 atggccgtcc agtattgatt cactttacca attcggatat ggaaaggatg ttcaaacgaa
    15961 tccaagaccc gcattaagtc aaagagaaga gggaaaacat gaagattgta ttagcatccc
    16021 aatcaccaag aagaaaagag ttattggctc atatcgtttc agaattcgag attgaacctg
    16081 ctgatatcga tgaaacgcca tttccagacg aacagcccgt cgattatgtt cgtagaatgg
    16141 ctgaagaaaa agcacgaact gtctgggaac aagatgaaaa agaagaccat ttagtgattg
    16201 ccagtgacac gactgttgtt ctcaatcaag agatcatggg taaaccagaa gatctggctg
    16261 aggctgaatt catgctgaaa aaactaagcg gggaaacaca tactgtatat acagctgttg
    16321 ttttaaaaac aaaggaacga gaagaacgga tactagcaga agcacatgtc actttttatc
    16381 ctttgacaga cgaagagatc aaacgctact tggagacggg ggattatgcg gataaggcag
    16441 gggcatacgg catccaaaat gctgcgagtg tattcgtcaa agaaatttct ggagattatt
    16501 acagtatcgt aggatttccg attggtgctg tcaatcaggc actgaaaaca ttcatttaaa
    16561 caaaaaagcg gactatctga ttttcgattg aaaatccatg atagcccgtt ttttttattg
    16621 aaaagattac ttatctactc tgactaagat tttacttcag ctttaccgac tgcttcgccc
    16681 gggcgaacaa gtcctgattg gtcaagagaa agtcctgcaa ctttttcatt attggtcaaa
    16741 gcaacaataa tgtcagtttt cttgccagct tgttctattt ctggcaaatc catttcagca
    16801 atcagggtct ctggtgtgac aaggtatcct tctttcacga atacattgaa aggaacaccc
    16861 tttagttcaa cagtatctaa tcccatgtga acaagtactt ccagcccctc attagaaaga
    16921 ataccaatgg catgttttgt ttcaaagaca ctcgtcactt taccgtttac tggtgcatag
    16981 actttgccgt ttgacggttc gacagcataa ccgtcaccca tcattttttg tgagaaaact
    17041 gggtcattta cttcagttat ttccttgatg gtccctgcag cgactgcgaa taatgtttct
    17101 tttgttgcaa ctgccgtacc agttgctgaa acaggttcga aagactgtgg cgttgctgtt
    17161 gcgccatttg ctgtttgaag ttgtacatca gcagcatttt caggaacagc aggatcaatc
    17221 ttattcaaaa ttccctgacg tctaaagatg atcgtcaagc caaatggaat gatgacagca
    17281 atgatcattg cgatgatgaa aggtacccat gtttctgctt ggatagctag tattcctggc
    17341 aaaccgccta ctccgatcgc gttagctcga acacccatca agttagcaaa catgccagct
    17401 aatccagagc cgaccattgc agcgacgaaa ggatagacgt atttcaaatt gattccgaac
    17461 atagcaggtt cagttacgcc taagtaacaa gaaatcattg ctggaatcga gatttgttct
    17521 tcttttttat tcccacgatg taagaagatg atggctaaga ctgcagagcc ttgggcgata
    17581 tttgataaag caatcatcgg ccataaattc gttgatccga aatctgcaat cagctgcata
    17641 tcgatggcat tggtcatatg gtggagacca gtaatcacta aaggagcata caggaatccg
    17701 aatacggcac taaacaacca gctgatagaa gacgtcaatc cagtatttac gatatttgag
    17761 atccagcttc cgactgtcca gccgatagga cctaaaataa cgtgtgcagc taaaacagtt
    17821 ggtaacaatg aaaacaatgg aacaaaaatc atcgagatcg actgagggat atatttgcgg
    17881 aagaagattt ctagatacgc taacataaac cctgccagca tggctggaat aacttgcgct
    17941 tgataaccaa tcatctggac ttgagcaaaa ccaaaatccc aaaatggaat atctgctgcg
    18001 gctgtggaag ctacactata agcatttaat aattgcggag aaactaacgt aattcctaaa
    18061 acgattccta atatttgtgt agtacccatc ttttttgcaa tactccaagt gatacctact
    18121 ggaagaaaat ggaaaattgc ttcacccggt aaccacaaaa aggcattgac accattccaa
    18181 aacttcgagt gttcaacgat tgttccacca agactttcaa actggatacc ttcaagtaca
    18241 tttctgaatc caaggatcaa tccaccgaca atgattgcag gaatcagtgg tgtaaagatt
    18301 tctgctaaaa cggcaatagc acgttgaacg ggatgaaggt tttgttttgc agctgctttt
    18361 ccttgttctt tggaaacccc ttcaactcca gatactgcaa cgaagtcgtt ataaaaagta
    18421 gaaacatcgt ttcctatgat gacttggaac tgtcctgcat tcgtgaacat cccttttacg
    18481 ctaggtatat cttcgatcgc tttttcgtcc gcttttcctg gatcattcag gacaaaacgc
    18541 atacgagtcg cacaatgact aactgcagca atattttctt ttccgccgat atcatgtaac
    18601 agcttctcgg catctgcttg atattttgcc atatcaataa acccctttct cttaacttgt
    18661 ctatgcaagt tgtttcttca tttactatac tttttttcgg agagaattgc aagcgtttta
    18721 ttaaaaagta cgagagaaaa tgatatcgtt ttaaaaagct taaaataagc ttttcttaaa
    18781 aataggaaca ttgaaataca aaaagagctg tagtatagtg aagaaatgat ggaagaacga
    18841 gtgagggaaa aaacatgaat aagttcaatg aaattttttt agatttggaa cagaaaattt
    18901 tagcgaaaga atatcctccg cattcgcttt tacccagtga gaaccaattg atcaaaattt
    18961 atggtgtttc acgagaaaca attagaaaag cgctgaatct tttgactacg gaaggttata
    19021 ttcaaaaaaa acaaggaaaa ggttcgatcg tactggatcg gaatcgcttc gactttccta
    19081 tttctggatt gactagctat aaagagctac aggagaccca acgtattcca agtgaaacga
    19141 tcatccatac gttagaagaa acagaagtga caaaagcatt gaacgagatc actggctggg
    19201 agatcggtgc gcctgtttgg catttgatac gcgaaagaaa aatcaatggc gaagtagtta
    19261 tattagacac cgattatcta ttaaaggaaa tcgttcctat tttaactcca gcacaagcac
    19321 aaggatcgat ctatgaatat tttgaaaatg agctttcttt gacgattgct tacgcgcaaa
    19381 aggagatcac agtagaagaa gtaacggaaa tcatgaaaac agcgatggat cttcacgatg
    19441 acacttatgc agtagtagtc agaagcctcg ttcatctgga agatacccgc tgtttcgagt
    19501 attctgagtc ggttcaccga ttagataaat tccgtttcgt tgagtttgcc cgacgccgaa
    19561 aagtgtaaat agttcaaaag aaagcaaatt gttggcatct gtccactttg gcgctatgat
    19621 aggatcacaa agggggcatt tttaatggat aaaccaataa gaccagaaaa agaagaactg
    19681 aaagaaaagt tatcacccat ggcttatgca gtcacacaag aaaatgcaac agaacgacca
    19741 tttagcggga aatatgatga tttttacgaa aaggggatct atgtagatat cgtcagcggt
    19801 gaaccgttat tcagctctgc agaaaaatat gatgcaggtt gtggctggcc atcattcagc
    19861 aaaccaataa cgaaaagaca agtgcgcgaa aaagccgatt tttctcatgg catgcatcga
    19921 atagaagttc gaagcaaaga agcagattct catctcggac atgtgtttac cgatggacca
    19981 gtagatcaag gtggtctacg ttactgcatc aattctgcct cactgaaatt cattccatat
    20041 gaaaagatgg atgaattagg ttatggggaa ttcaaatcac ttgtagaata atggaaatac
    20101 acaaagagcg gtacaatacg gggatttact cgatcgtccg ctcttttttt attcaagcga
    20161 ttgctatttg aaagaaacgc tccctagact ccttttttca caaggtgaaa tgtgctacaa
    20221 taaagggaac gtatgtgtgc aaaagaaaga ggactagaat atgtatgaat atctgacagg
    20281 tgtggttacc tttatcaacc cctattacat agtagtagaa accaatggta tcggctacca
    20341 gatcgcacta ggaaatcctt accgctacag tagcaaacta aatcaaaaaa taaaaattta
    20401 tgtccatcag gtaatacgtg aagatgcgca tcttctgtat ggatttgatt cgctagaaga
    20461 aaagcaactg tttttgcgat tagtaagtgt ttcaggaatc ggtccgaaaa gtgcccttgc
    20521 aatcatggca agcgaagacc actccggttt gattcaagca gtagaatcca gtgatgtcac
    20581 ttatttgacg aaatttccag gagtagggaa aaagacagca caacaaatga tcttggatct
    20641 aaaaggaaaa ttcggtgagc tgagtatcga tacacctttt agtctatttg atgaagcaaa
    20701 cacaaaagac gctacagctc tatctgaagc aatagaagct ctctcggctc ttggttacag
    20761 tgatcgagaa atcaaacgtg tagaaaaaca attaaaagaa gtagataatc agacaacgga
    20821 tgagtatcta cgccaagcac tcaagctaat gatgaaaaaa taaggaggag accaaatgac
    20881 agatgaatac ttgttatcac cagaatctgg cgaaaatgaa ctgagtttgg aaaaatctct
    20941 tcgaccacag ctgctttctc aatatatcgg acagagaaaa gtcaaacaag aacttcagat
    21001 ttacatcgaa gctgccagaa atcgggaaga acctttagat catgttctgt tgtacgggcc
    21061 tcctggatta ggaaaaacga cgatggccat ggtcattgct aatgagatga ccgtaaatat
    21121 tcgtacgacg agtggccctg ctatcgaacg tccgggtgac ttagtagcaa tcttgaatga
    21181 actggaagca ggggatgtcc tgtttatcga tgagatccat cgattaccta gagtggtaga
    21241 agagatgctt tattcagcta tggaagattt ctatgtagat atcatggtag gacaagggcc
    21301 aaccgcacat ccggttcatt tccctcttcc tccctttact ttgattggcg cgacgacacg
    21361 ggcaggtatg ctttctgcac ctttacgaga tcgatttggc atcatttctc atatggaata
    21421 ttatgacgaa caggatctgc aggagatcgt tttacgttct tcggatattt ttcaaacaga
    21481 gatcattgaa gaaggggcat tggaaattgc tcgccgatca cgaggaacgc ctagaatcgc
    21541 taatcgcttg ctcaaacggg ttcgtgattt tgcgcaagtc caaggagacg ggaaaatcga
    21601 tcgtcctata gcggatcagg cacttacttt gctacaggtc gatcaggctg gattggatta
    21661 tgttgaccag aaattgttgc gaacaatgat cgagttatat ggcggcggac cagtagggtt
    21721 aagtacgctt tcagtaaaca taggagaaga gcgtgagacg gtagaagata tgtatgaacc
    21781 gtatctgatc caaaaaggat ttttaaagcg tacacctaga gggcgaattg ctactgctta
    21841 tgcctatgaa cattttggtt acgactatca tatatgattt ttgcttttag attggaggaa
    21901 aatgaatgag tgatacaaca cgtacgaaac aattgatcaa aaacgtattg attgatttgt
    21961 gccaaacgca atcttttcga aaaatcagcg tccaaaaaat cgcaaacgaa gcaaaaatca
    22021 atcgacaaac attttattat cattttacag ataaatacga tttgcttcgt tgggtctatt
    22081 gtgaggatgc attgcattat ttagatccac aatgtctttc acttgataat tgggaagagc
    22141 aagcattgaa aatgctgaaa gcaattgctg agaagaaaga attttatgca aatactgtgc
    22201 tttctgaccc agaaatttta caaaaagagt tttctcaact gatccaaaaa tcatttatca
    22261 agatttttga acaaatggat gaagaaagac aactttctgc aagagacaaa ctattttatg
    22321 ctcgtttttt ttcttacggt tgcagtggtg tattagtcaa ttggatcacg aatgaatatg
    22381 aagaaacacc gatggaaatc gctatgcagc ttttccgttt agccaaggat acggaattat
    22441 attcttatcg tctttatgca aaagaagagt tggaagaaca gtaatagaaa aattttttgt
    22501 tggaaaagca ataatcgcta aaaggagatg gggaaatgac aaaaatttta tttgtttgtt
    22561 tgggaaatat ttgccgttca ccgatggcag aaggcttgct gagaaaacga atagcattag
    22621 aaggaaggga agcagaattt tttgtggatt ctgctgctac aagcacgtat gaagttggaa
    22681 agacaccgca ccctggaacg aaaaaaatat taaaccaaga aaaagtagat atgacgaata
    22741 tggttgctcg gcaaatcaca ccccacgatt ttgaaacttt tgattggatc attggcatgg
    22801 atcaagaaaa tgtagaagaa ctgaaacgaa gagcaccacg ctcagcgcag gggaaaatcc
    22861 atttgttttt aagtagcatt cctggaaaag aaaaagaaaa tgttcccgac ccatactata
    22921 ccaataactt tgatgagaca tatcacttga tcacagaagg cctgaatcat tggtggaata
    22981 tttggattga tgaaaataaa ataacaaata atttgtaaag ttaacgcttt ctttttaagg
    23041 cgatgttaga gcatttcctt gtttttttgt aaaatgttag gtaaaataaa attaattaag
    23101 taacactttc ttagctaaag gaggagtgca ttcgatgaac gaagagacag tatcgccaat
    23161 gaagaagctt acgaagttag ttactcatac ttcgtatcaa ctttttgatt cttttgtaaa
    23221 tgacactgaa gaacatgcta agaatgtacg attgcaagga aagtttattc ttgagctgca
    23281 aaaagctgct actgaacata gtctagttat cttacaagta agagcaaatc gtttgagtag
    23341 caagtatgaa acgatctcag gctgggtggc gacaaaaacg gtcgaaaaag accgagtgat
    23401 gatccgccta caaaacgaag agcagcagat ccggatggtt cctgtagaac aaattgaaaa
    23461 aataacaatc ctttcaccag caggggaaca ggaacggtta tcaaaataat ttataccaga
    23521 tagaaaagca cgtatgagct tgtaccatca atcattacta atcaaaaata accgaatgct
    23581 ttaagctgat atcagtaaaa cggaacgttt taggatgagt atcatagcat gacagcattc
    23641 ggttgattag ttgaatcgat tggatggtac aagttttttt gataaaaaaa ggtcctgcta
    23701 gccggggagc tagcaggata aggagttaaa aatgaaaaag tgttgttagg gttgtttgtt
    23761 ggtatgctta tataatagtc attagttgtg aatattttgt gacgaaagtt ttcgaaagtt
    23821 gttaagtt
//
LOCUS       DAYNVV010000041        23460 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.041, whole genome shotgun sequence.
ACCESSION   DAYNVV010000041 DAYNVV010000000
VERSION     DAYNVV010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.041"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(74..655)
                     /locus_tag="ACGXWR_001839"
     CDS             complement(74..655)
                     /locus_tag="ACGXWR_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ReoY family proteolytic degradation factor"
                     /protein_id="HFK0803395.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(661..1920)
                     /locus_tag="ACGXWR_001840"
     CDS             complement(661..1920)
                     /locus_tag="ACGXWR_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFK0803396.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(1922..2968)
                     /locus_tag="ACGXWR_001841"
     CDS             complement(1922..2968)
                     /locus_tag="ACGXWR_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803397.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(3203..3478)
                     /locus_tag="ACGXWR_001842"
     CDS             complement(3203..3478)
                     /locus_tag="ACGXWR_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFK0803398.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(3721..5031)
                     /gene="der"
                     /locus_tag="ACGXWR_001843"
     CDS             complement(3721..5031)
                     /gene="der"
                     /locus_tag="ACGXWR_001843"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HFK0803399.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(5213..6442)
                     /gene="rpsA"
                     /locus_tag="ACGXWR_001844"
     CDS             complement(5213..6442)
                     /gene="rpsA"
                     /locus_tag="ACGXWR_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HFK0803400.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGGILG
                     DALKEEVEEKATDDSEK"
     gene            complement(6577..7257)
                     /gene="cmk"
                     /locus_tag="ACGXWR_001845"
     CDS             complement(6577..7257)
                     /gene="cmk"
                     /locus_tag="ACGXWR_001845"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HFK0803401.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(7306..7941)
                     /locus_tag="ACGXWR_001846"
     CDS             complement(7306..7941)
                     /locus_tag="ACGXWR_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HFK0803402.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(8007..9410)
                     /locus_tag="ACGXWR_001847"
     CDS             complement(8007..9410)
                     /locus_tag="ACGXWR_001847"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HFK0803403.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(9397..10428)
                     /locus_tag="ACGXWR_001848"
     CDS             complement(9397..10428)
                     /locus_tag="ACGXWR_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0803404.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            10459..10680
                     /locus_tag="ACGXWR_001849"
     CDS             10459..10680
                     /locus_tag="ACGXWR_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HFK0803405.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(10845..11582)
                     /locus_tag="ACGXWR_001850"
     CDS             complement(10845..11582)
                     /locus_tag="ACGXWR_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HFK0803406.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(11735..13075)
                     /locus_tag="ACGXWR_001851"
     CDS             complement(11735..13075)
                     /locus_tag="ACGXWR_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFK0803407.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(13312..14835)
                     /locus_tag="ACGXWR_001852"
     CDS             complement(13312..14835)
                     /locus_tag="ACGXWR_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFK0803408.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(15213..15824)
                     /locus_tag="ACGXWR_001853"
     CDS             complement(15213..15824)
                     /locus_tag="ACGXWR_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFK0803409.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(15947..16072)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(16154..16870)
                     /locus_tag="ACGXWR_001854"
     CDS             complement(16154..16870)
                     /locus_tag="ACGXWR_001854"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFK0803410.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(16876..17445)
                     /gene="scpB"
                     /locus_tag="ACGXWR_001855"
     CDS             complement(16876..17445)
                     /gene="scpB"
                     /locus_tag="ACGXWR_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HFK0803411.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(17429..18199)
                     /locus_tag="ACGXWR_001856"
     CDS             complement(17429..18199)
                     /locus_tag="ACGXWR_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HFK0803412.1"
                     /translation="MNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDIPIATITEQY
                     MNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEEDPREELVTQ
                     LLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKKIDLIRAMQK
                     ILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESPSKSEVVTTF
                     MALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(18196..18567)
                     /locus_tag="ACGXWR_001857"
     CDS             complement(18196..18567)
                     /locus_tag="ACGXWR_001857"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFK0803413.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(18586..19473)
                     /gene="xerD"
                     /locus_tag="ACGXWR_001858"
     CDS             complement(18586..19473)
                     /gene="xerD"
                     /locus_tag="ACGXWR_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HFK0803414.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(19569..20042)
                     /locus_tag="ACGXWR_001859"
     CDS             complement(19569..20042)
                     /locus_tag="ACGXWR_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFK0803415.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(20147..21010)
                     /locus_tag="ACGXWR_001860"
     CDS             complement(20147..21010)
                     /locus_tag="ACGXWR_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor B family protein"
                     /protein_id="HFK0803416.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYGFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(21206..23305)
                     /locus_tag="ACGXWR_001861"
     CDS             complement(21206..23305)
                     /locus_tag="ACGXWR_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division site-positioning protein MapZ
                     family protein"
                     /protein_id="HFK0803417.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
BASE COUNT         6419 a         4992 c         3938 g         8111 t
ORIGIN      
        1 acaaagatag gctatgagga aagattccac atccagctga cctttgtctt ttttagtact
       61 atactatttt taactaattg ttatgttcac ttacccggtt acttttcttt tgtgtctgca
      121 aaaggatctt tcggttaact tcatcagata atttcaaaaa agcatcccta tctccatctt
      181 ctagtgcttg atcgatttga gcataaagca tttttagttt tgcctcttct tctttttctt
      241 gaaaatatcg ttcaattaat tcagtatctt cttcactgac tgaagaatcc caagaagaaa
      301 atggattgtc ttctaagata gatagatatt ctcttgtctg ccaagcattt tcgaatatac
      361 attccacata taaaggcttt ttccaattca aacggatttc atgaaaaatc tggtctgtgt
      421 ccgtaaattc ttttccctgc aaaaacaatt tcatgggttc cccttcaaca gatagatcac
      481 tgatctgcag tcctcgatcc gcaaaattcg ccccttcaac aaagtggaca ttgcttaaaa
      541 tcgcttcatg attggcaaga taattcaaga tccaaaaaac ttctcttcgg ctaaaagata
      601 catgattgac catccacgtt aaaaaattct tcttttcccg tacatcaatt agcatttttc
      661 tcacctctct gttaggtcat ctaataatga cagtgcctcc atatctcctg gttcaagtgt
      721 taaataataa gtcaataatt cttgcgctct tttcagctgc ccttcttctc ttaagaaaaa
      781 ggcatactct ttcaagaaat ctggttcatg tgatagttca tgataagcct gttcatagtg
      841 tacagctgca acggtaaagt cttctaattc attataagca tgggctaggt tccattctgc
      901 ataaggatta gcagtttctt ccatctgatt gatcacttgt atcacatctt catatctttc
      961 atcatccaag taaagattac ttaaagtaag taatgtttca tcttgtttgt ctcctacttc
     1021 taaagctttc agtaaaagtt cttctgctcg ctgtctatca tgcagacgga aagcattttc
     1081 cgaggccagg tgataaagtt cgacttggta aggattttct ttgattcctt cttctaacac
     1141 tgtttgtgct tcttcaatca tttcttcttc ttgaagagct tgtcctagat atagatataa
     1201 cgattgataa tgcggattaa cttctcgaag ttcttccaga tagttgattg cctgctgatt
     1261 ttctttcaat tgaagattcg taaaagctag ctggaacagt cgatcatctg tcctttcttc
     1321 tttcagtgct tcttctaaag gtacgatagc tgcttcgaat tctccttgca tacttaagga
     1381 ttgtcctaaa cgttcctgca tcgagattcc tgaaatttca tttatcccgc ttgccaacaa
     1441 tgtttcataa accactgctg cctctttgaa acgatcaact gaaaaataca attcagctag
     1501 cgcaaactgg atcaatggtt catcaggaag caacccagct gcttctttca attttgcttc
     1561 actcacttca gggattccga taacttggta caaatcagct atcgccaata agctttgcgg
     1621 atagtaatca ctttgcttat ccactttttc caggtattca aaagctaagt cgatctcatt
     1681 atcttcgatt gcaatttctg ctaacgggat gttcagtccg tcattttctg ggtattggtt
     1741 gatcagttgt tcaaaaatct gttttgcttc gatcaaaaag ccaatagcca gcaattcttc
     1801 gcctagttca gctaatatat ctgctgggtc ttcttttaat gctttttcta aaaagatttg
     1861 tgcttgtgac aagtcttcat ctgataaagc ttgcaacatt ttttcgctat ttgtattcat
     1921 ttcaattccc tcttatctca ctgacgattt gttgaaatac cgtcattgtt ctcaataatt
     1981 ctttttcgtt tggatgttgg tatccgtcta ttatacctat tttttctaaa acaagtattt
     2041 ttttgctttt ttctgccaaa aaaagaactt tttccaaata ctccatcttt gaaatctgtt
     2101 ccagccagtg gattggatag ccaagcaagt ccagccacac aaaaaagttt tttagttgga
     2161 aatcaaaagg atatgcttgg agattccaca cgaaatgaaa catcattcct aaaaattttt
     2221 tcatactagc agaaagtaga tggccatttt cggtcagata aaaagcttgt tcaaacagtt
     2281 taccataatt tgacaggttt tctgcctcta attgataaaa atagatcatt tcttcgatca
     2341 tcccggcaaa cggccgagtc gttaattgct ttttatttgg atagttttta tacagatttt
     2401 gcaaaaaacg atgatcacaa atcattccgc aacagataaa agtcaaaaag tcaatctgct
     2461 ttccgtccac ctgccgctcg ctgattgttt gatcataaac gatgcgttct ggcagattga
     2521 tggtttgcag cactacacga tttggtagct gcaaaatcgt ccgctgcggt gttaatgctc
     2581 ggcttagaga acggatcgat acagggatca tccatagtga tgaatcaagg gttgtatgtt
     2641 tttgaaaaaa acctgccaga tccatgatcc cttcatttcc aaatccgatg ataaacatgg
     2701 attgattttc gggatagcgt ttgacgaaat caagcaggtt ctttaattct gttaaatgat
     2761 tgcattgagt gttggcacaa atataccagt cattgtttgc ttgatttgca aataacgggt
     2821 tgatcttatc tgcaaacaaa tcataatagc gctgattcgt taaaaataag attggctgat
     2881 caatggaaag ttctcttagc tgactgacta gcgtttctcc gtaaaacact ttcgtcaacg
     2941 catcttctac ttgataatca agttccatac gcatccctcc tcttcttatt tttattttac
     3001 cattagtaag caaattctag aaaagataag agcaaagctc acctcataac ttgcaaataa
     3061 ataaaaatta aataaaatac atgtgttttc tatgtatgac atacggattc ggaatctctg
     3121 tctcttattt attccttttc tgctaggaaa taaaaagaaa agcacttgta gccctagagc
     3181 cacaagcgct ttttcaactg tcttatttaa cagcgtcttt taatgcttta cctggtttga
     3241 atgcaggtac tttgctagct ggaatttcga tttcttcacc agtttgtggg ttacgacctt
     3301 tgcgagctgc gcgttcgcga acttcaaagt taccaaaacc gattaattga actttttcgc
     3361 cgttagctaa agcatcttga atagttgaaa atacagcatc tactgctgca gttgcatctt
     3421 ttttagttaa atcagtagct gaagcaactt tttcgattaa ttctgctttg tttgccatgg
     3481 atagattcac ctcctccaca agagatatga tagaaatatc atttagttaa aactttctga
     3541 gtggtccaga agtttaaaaa gaaatattga ttaacttcaa tattctgtta tcacgatatc
     3601 atatgaaccg cttaatagca aggtttttac caattttcac atgctttttt tagtcataga
     3661 aacgtaacaa acgaaactgt ctttttcttt tgaaaaaaaa acgtcgatat ggtaaaatgc
     3721 ctattttctc ctacgaggga taattcggat ggacgtccct tcaaaagtaa atgcttttct
     3781 gatttgattt tctaagaaac gttcataaga aaaatgcatc aattcctctt cattgacaaa
     3841 aacgacaaat gtaggtggtt tgacagcgac ttgtgtagca taaaaaatct tcaggcgttt
     3901 tcctttatct gttggtgttg gattgattgc tacagcatcc ataatgatat cattcaacac
     3961 agccgaagag atacgaagat tctggttcat acttacttgt tcgatcattt caggcagacg
     4021 ttccaaccgt tgtttagtca ctgcagaaac aaaaacgatt ggagcgtaat caagataccg
     4081 gaattcatca cgaatctctt gttcgaaatc acgcattgta ttggtttctt tctttacaag
     4141 atcccattta ttcacgacga taataattcc acgaccagct tcatgggcgt aacccgctac
     4201 tcgcttgtct tgttcccgaa tcccttcttc agcattcagt accatcaaaa cgatatcaga
     4261 acggtcaatg gcacgcattg cacgcatcac gctgtatttt tcagtatttt cgtatacttt
     4321 tccgcgttta cgcataccag ctgtatctat cattaagaat ttctgaccac tttcagaaac
     4381 gaagtgggtg tcgattgcgt ctcgggtcgt tccttcaata tccgaaacaa ttacacgttc
     4441 ttctcctaaa atcgcattga tcaaagagga tttaccaaca tttgggcgac caatcaaact
     4501 aaacttaatc gtgtcgtcgt cctcttcttc agtctcttca gagaaatact tcactgcttc
     4561 atctaaaata tcaccaatcc ctagtccatg gcttcctgaa acaggataag gatcgcctag
     4621 ccctaaggaa taaaattcat agatatcgtt tctcatttct ggattatcta ctttattgac
     4681 tgctaaaatc actggtttat tacttctgta taaaattttc gcaaccatct catctgcgtc
     4741 tgtcacgcct tcgcgtccgc tgactacaca aatgattaca tctgcttctt caatcgcgat
     4801 ttctgcttga tgcttgatct gatccataaa aggttcatcg ccaagatcaa ttccgcctgt
     4861 gtcgatcacg ctgaattctc gacctaacca ttcacctttt gcataaatac gatcacgagt
     4921 tactccagga gtatcttcga caatcgagat acgctcacca gcgatgcggt taaaaatcgt
     4981 agacttaccg acgttcgggc ggccaacgat tgcaattgtt ggatttgcca tattatttcc
     5041 tcctcacaag tttccaatct cacttagttt aacgaatgca ttgccaactt tcaagcatag
     5101 attgtcaatt aaacgaagta tttttattcc ttattgaaat actaatcgct tttcaaaaga
     5161 aaaactgaga caaaagcagc tgctttcatc tcagtcacag atacaaaatc aattattttt
     5221 cagaatcatc ggttgctttt tcttctactt cttctttcaa cgcatcacct aaaatgcctc
     5281 ccatagtaaa tccagtattt tcttctggta attcataaga ctcaacattt tttggttctt
     5341 cttctgaagc tggtttttct tctaaagctt tgatactcaa tgcaatacga tgttcttctg
     5401 gatggatctc taatactttc actttcactt cgtcaccttc atgaagcact tcatgtggtg
     5461 tcgcaatatg tttatgtgaa atttgagaga tatggactag cccttctact ccagggaaca
     5521 cttcaacaaa ggcaccgaag cttgtcaaac gtttaactgt tccgtctaat actgtgccaa
     5581 ctggagcttt tgtatcgatt tctgaccaag gtccaggctg tgtgtctttg attgacaagg
     5641 aaacacgttc ttgttcagga ttgatagaca acactttgac atttacatca tcattgacag
     5701 ccaatacatc acttggtttt gctacatgac tatgtgaaat ctctgagaca tggactagac
     5761 cgtcaattcc gcctaggtcg acaaatgcgc caaaatcagt aagacgtgca acacgtccac
     5821 tgagaacatc tccctcatgg atagttgaaa gaatttcttt tttcttttct tctctttcgt
     5881 tttccactac cgctttatgc gataagatca aacgattttc tgatggttcg atttcgatga
     5941 ttttaaagct caatgttttg cctttatagt ctgaaaagtc tgcaacaaaa tgatcttcca
     6001 ccattgatgc agggacaaaa ccacgtacac cgacgtcaac gactaaaccg cctttgacaa
     6061 catttgtaac aggtgcttcg atgaccttgc cctcttggaa atctctttcg atatcttccc
     6121 aaactttttt agcatctaaa cggcgttttg aaagtagata gctgccgttt tctttatctt
     6181 tgccgatcgt actgataacg actaaatcta atacatcacc gacttttact acttcgctga
     6241 tatcttctac cggcaaagtt gataattctt ttgccggaac gactccttca actccagccc
     6301 cttcgattcc gacaatcact tgtttgtctt caatgactaa aacttcgccc ttaacaacat
     6361 cgccaacttt tacttcttgt acgcttttca ttgcgtcttc cattgactgg ttgttctctt
     6421 gattttgatc aaattctgtc ataacacttg tcctcctaac caacattctg ccgtaagtac
     6481 ggtactgttt ttagtttaat tgattattca aaaaaaataa agcgatttcg ttcgttttcc
     6541 ttgaaaaaac aattgttttt catttttttt cttaatttaa aaaagaagat aacctttttt
     6601 caaaacaaca gcttttattg ctgcaacgac ttctggaatc gatttgccag tcgtatcgat
     6661 acgaacagca tcctctgctt gcttcagcgg agagacgtcc cttgttgaat cataatggtc
     6721 tctttcctgt atctctttcg tcagtgtttc aagatcagtc ggaattcctt tttcttggtt
     6781 ctctttgaaa cgtctttctg cacgctcact tacgcttgct actaaaaaga ttttcacttc
     6841 tgcattcggt aatacagctg tcccgatgtc tcttccgtcc atgacaacgc caccgcgttc
     6901 ccctattttt cgttggacag caactaattc ttctctgact tttccatgtg cagagacttc
     6961 agaaacagct tttgtgacat ctggttgacg gatttctaaa gtcacatctt ttgatgctat
     7021 gaatacatgc tgtccatctt cttgttgcga aaaagagata ggatactttt tgatcagcga
     7081 aactagccct tcttcatctg aaaaagatac attgttcgta atagctaaat aagttactgc
     7141 gcgatacatg gcaccggtat ctgtataaat ataattcaat tcttttgcta atatcttggc
     7201 aacggtactt ttcccagatg aagcaggccc gtcgattgca atactgattt gtgtcatgat
     7261 ataactcctt tttctcagaa aaaaagccgc aaagcgcggc tattattatt taattcttaa
     7321 ttcttgacca gggtaaagca taaagttgtt tggatctaag ccattcaatt caaacaattg
     7381 atcagtggtg atccctgcac gctcagccac ttgttttgga ccttcgcctg cttgaacagt
     7441 cgttgttgaa ccggctgcag ctgatgaaga aggtgttgtt tctgctgcat tgctgcttga
     7501 atcccctgct tgataagttg cctcacttga ggaagtcggt gttgtctctg ctgcaatact
     7561 gctttctgac gttacacctg tatcttgaga cacagtagat tcttccgcga ttgtactaga
     7621 ttctactgtt gaagtctcag ttgactcctc ttttgttgta cttgtagaac tttctactac
     7681 tgatgtcgaa gtttcagaag aagttgctgc tgttgcattg ttgcttgatc catttctgat
     7741 ccagaaataa gcacctgctg gaatagcgat acataagacc agtaaaatca aaaatagcga
     7801 aagaaataat gtatttcctt tcttttgttg tctctgagaa cttcttgatg aaacttcatc
     7861 atctgtatcg tagattggtt gttcccatgg ttcttgtgtt tcgttatttt ctgtagattg
     7921 atgtctatct tttctgctca ctgttttacc tcctaaactc tatcgtgtgt attataccat
     7981 aggaaaaagt gtcttgtcct aaaaaatcaa tgttccatgt tttttttaaa taaatttagt
     8041 aaaatcgttt cccaatgaag ttgttcagtc ttagaaaaaa gcttcctctt tggcagaagt
     8101 tctgcttttg ctccatcaat atcacaacaa ttctgcggct tttcggagag tttttcgcca
     8161 aaataagcta agatgaattt tctgcggcag ttttcttcat taatatagcg aagcatctgc
     8221 tgcaggcgga attctttttc tttttcctga cgtttgagcc gttccaccca attttctggt
     8281 ttttcagact gctggatcag ctccatccat tttttttgca gctcatcaaa gggagcttgc
     8341 tctgtggcat attccaaata aagctcaaaa ctttgtcgct gttctctaga aagttgatta
     8401 aagaaataat ggatacgttc atccccactt tgataaaaaa gaattgctgc actttcttcc
     8461 tgatctctgc ctgctcgacc gatttcttgt acatagtttt ctagactgtc tggcaaatca
     8521 taatggacca cataacggat atcagattta tcgatcccca taccaaatgc attcgtagca
     8581 atgagaaact gcagctgatt ttttacaaac tgctgttgaa gttgtcttct ttgagctgca
     8641 tcaagaccac cgtgatagta tccaactgta aaacgttccc tgaataaatg atacaatcgt
     8701 tcgacttctt tttttgttgc acaataaatg attgccgctc cttgtgctct ttccatgaag
     8761 tgttcaagtt cttgttcttt ttgctgcgtt ttccgaacaa aaagcgagat attttgccga
     8821 ttgactgatt gtctgatctc ttttggtggt cgatcaaata gtacatgacg tatatctctt
     8881 gctactaaat ctgttgctgt cgccgttagt gccagtgtga ccgggtttcc taaaagcttt
     8941 cggatttttc ctaactgttg atattctgga cggaaatcaa ctccccattg agacacgcaa
     9001 tgagcctcat ctactacata taacgcaata ttttgttttt tcagatgctc taaaagagaa
     9061 ggattagtca acatttcggg actcaaaaac aaaaatttat attgcgatag atgacggagg
     9121 acgtatcttc tttcagattg cgaaagtaaa ctattgaaag cagctactcg tttctcccct
     9181 cgtttttgta attgcgtcac ttgatcttcc attagagaaa gcagcggtga cacgatgatg
     9241 accagacctt ccattaaata ccccgtcaat tgatagcaaa ggctttttcc cgttcctgta
     9301 ggcaaaatag cgagagtatc ttctccatca agcaacgcct gaataatttc ttcttggccg
     9361 ggacgaaatg aatcaaatcc aaaatatttt tttaattcat ttattaacat tctgtatcgc
     9421 ttcctttctc aatagataga tttgatacaa acgaaattct ccataatcta attgtccatc
     9481 tacattccat tcgctaaagc gccactctcg cacggaatcc ttatttggtt ccaaacgttc
     9541 gattgtttct gcagagagaa tccactcgta tggaaaatca tcaaaaaaca aggcccactc
     9601 aataagatga tctgttactg ttcctctttt taaatgacgg attgccatga tctggtcaat
     9661 tgtctgacca ttcataaaca tctgcttggt gatcatcatg ctttgattga aattttgctg
     9721 taataatgaa tcgatcaaag cgtgccaaag cgaatctggc cgtttttcga tttgtgctaa
     9781 caaaaggtgg atacatctgc tttgttgcag ataaaccgct gactcatcat tgttttttgc
     9841 cagctgataa ggaagcagcc ctgttcgctc atttccagat aattggttag ctaaaaaatc
     9901 tgctgcttct tctggtatct ccgaaaacag ctgcaccaaa ctctcatacg cagtatcaat
     9961 caaaatttca cgtggcaatt ggctttcact aagccatttt tttagttgga aagtataaaa
    10021 aggacttgtc tctgctggaa gatagtcttg aatacccgtt gccagattag aaattacttg
    10081 aacagcaaat ttaatgagcc gccaactagt ttcccctgtt ctgccatagc ggtcaaaacg
    10141 caaaccagta tgttctattt gatgttcgga caacatatca gcccctgcag gcgttagctt
    10201 tgcttcattt tcatttattt cgatccaacc ttgctgcgca attttttgca aaatttgata
    10261 aaacttatcc tgcttcaatt ctggaaaact gttatggata aacaaaagtt cgtgggtaaa
    10321 tccataaata agtactgaag tcgttcgttt tcccacaagg agttggtaaa gagaactaat
    10381 ccgcagcttg tgtcctgatg aaaatagcga taaaataaaa acaatcatat tattctcctt
    10441 aagttaggat ggttagaaat gtcactacta tgtaaacttg tacctgaacg ctgtattgca
    10501 tgcggtcttt gtcaaatcga agcgccagat attttcgatt atgatgaaga aggaatcgtt
    10561 ttatttgccc aagaaccaga ggctcatcaa cagttcgtga tgccggaaga agaaacatat
    10621 gtaaaaaaag cgtatcaaaa atgtccagtt cgagcgattt tattagaaaa taaaatataa
    10681 atataaacga aactttaaaa acgtacacta agttctctaa acttgaaaat aagccgggat
    10741 ctgtttctct tgttccgtga aatcccgact tattttgaaa gattcatttg ctatctatag
    10801 ttaattgact agttttttca cggaccctat aggacccatt tatattattt caactttttc
    10861 agccagtttt ccaatgtatt gacgatcaca gtttgctggt ctgcgttaga aatttctgcc
    10921 tctccatctc ctttttgctc accatagctg ccaaaacctc catgatttcc gccattgatt
    10981 gatacatact ctgttctttc cggtaaatac tgcttagctt cttgataagc ttcctgattc
    11041 aatactttat cttttgtcgc cgtgatcgat aaaacaggaa cagctgattc tgtcaatgtt
    11101 ccttttttgt cgggataact tgccatgaag aatacccctt ttaaatgttt gtctgaatga
    11161 ttcttattga cataacgact tgccattacg ccacctaatg aatggccacc gatcacataa
    11221 tcggaatttg gaaaatcttc tttgacctta tccgctttgt ttccgcccat cactgctaga
    11281 tcaagtggca ttttgacaat agcgactgaa aagccgtttt ttgctaaatc ttgcgcccaa
    11341 atactataac tttctggctc tacgagagca ccaggataaa aaataagtaa tggagacttt
    11401 ccatgattct ttttctctcc ttcaaaaaat aagtaatctt ctttgttttt tccttctttt
    11461 accaacactt gcgcttctga cgatggttcg tacgtatttt gctgtatata gtaataaccg
    11521 gctccaccga gtaatcctaa aatgatgact aagccaatta gtattcgtct aaatattttc
    11581 actttctccc accttttcta tctgagtgac ccctttttct taatcaagta tgattatacc
    11641 ttaaaaaaat aagagagaaa tgcaaacttt ccagcatcaa ataaaaaaag acggaatatc
    11701 catttgaata tccgcccttt ttgtatgttt atttttattt agcacataaa cgatacacag
    11761 cttctgcata aatttccatt gctttataca tactacttaa ttcccatcgt tcattcgcct
    11821 ggtgcataaa gtcaggagta tcagggaaca tcgcaccgaa tgccacacac tggttcatcg
    11881 tacgagcaaa agtagcgccg cctgatacaa acggttcagt catgtctcca gtaatatcgc
    11941 gatatgtccc caatagattt ttcactaact cactgtctag tggcacgtat aatgaatcaa
    12001 ggaagtcaaa ttcttcataa gtcaacccat atttttctgc tgttttagtt aatttagcta
    12061 ctaaatcatc tttcttgaat gtaacaggga ttctcatatc tacaccgatt tttgtttgtt
    12121 ctggtgtgat ttccaaactt gcaaagttca tcgttagctc gccggattgt tcatcttctg
    12181 ttttgcccac gacagcttca ccagttgcat tttcttgaac taattttcct aagaaattga
    12241 ttgggccaaa atcaaatact tctgaaagag caattgccag acgagaaata gcattcactc
    12301 cttgtgctgc atctttcgcg tggatacttt taccaagaac gacgatgcct tcaccttgtt
    12361 cttcgaaatc gaattcgtgt tttttcaatg cttcttttac ttcagaaagc ttttctccag
    12421 agtaaggagc tgcatcagga acaacattca acgctcctcc agcttttaca gaaaactcgt
    12481 tcgttcctgg tcctgtcaag taagcttgca ataagccttt ttctgcataa attaaaggaa
    12541 attcagcatc tggcgcaaat ccttgcgtaa ttccttcttc tttttcgtta tatttttcta
    12601 aacaacgcca taaattttct tcatctgtac caaagataaa acgaatacgt gtcttgaatt
    12661 ccacgccagc atcaatcaaa gctttgacgg catacattgc cgcaatagaa ggacctttgt
    12721 catcttggga tccgcgacca actaaccagc cgtcttttat agttggatcg aatggttttg
    12781 tttcccaatt attttcgtcc cctgctggaa caacgtccat atgacacaag ataccgaata
    12841 attcatctcc agagccaatc tctgaataac cgtaatagcc ttctggatct ttaaatgttc
    12901 taaatcctag cttttcactg atttccaata ctttatccaa agcttcaatc acttttttac
    12961 cgaagggatg tccttgtcct gaatctgctt catctagtac ggaaggaatt cggatcaatt
    13021 cgctcaatga ttctaatgct tgttcatgat gttgttctgt cacaaatttt ttcatgatat
    13081 tatcctccta atatgttaaa aagggtcatg tcaaattcct ccgacacaac ctcttcttct
    13141 caaataatga cgttttaagc ctgctccatc agcaagcaga atgttcttaa caaatgatga
    13201 aagaaaaaac actcactgaa tggagctatt gacttatcca cgtgcttatc gatagccgtt
    13261 tatcggtttc ttcattctta tgatagacct tgtacctgta tttgtctagg tttagaacat
    13321 tgctgctaca cctaggatca cacagatggc tacaaataat atcgcaatta atttaccggt
    13381 aaatttccac cacactgaaa catcgaaacg agcaattgct acagcaccca ttacgatagc
    13441 agatgttggt gtaattaagt ttactaaacc agatgcagat tgataagcag tgattactaa
    13501 atccttaccg acgccggcaa attcacccat aggtcccatg attcccattg ttgcagcagc
    13561 taagccggaa gttgaaggaa tcaagaatga catagggata tagaaaataa atgtaataat
    13621 gatgaataca cttgaagata atgaacttaa tccttgttcg ccccaatgta agatggtgtc
    13681 tgtgattaat ccattgttca taaccacttg gataccacga gcaacagcta ctacgattgc
    13741 tacaccgatc aaatcagaag caccagctaa aaattcagag acaaattcag actctttcat
    13801 gccataagtg attgctacta cgatggacat tactaagaat aacatagtaa tttctgggaa
    13861 gtaccagtca cctaatggaa gcatgctttt acctagaacc gtacctagta ccggaaggtt
    13921 tgttaaccag tttgtcaatg attcaaaaat cgtgaaattc gcattcaagg ttgtccaagg
    13981 aatcaaactg atgatcatga taccaaaagt aataaagaac aatacattaa catgtttttg
    14041 ttttttcgtg attacttctt gacgaccgat tgcttcaata tcgaaatgct tcatatcttc
    14101 tttacgttgg ttgtatacta atgattttgt tggatctttt tcgatctttg atgcataacg
    14161 atacacatat acaatagaaa tagctaacaa aataacgaac atcaagaatc gaagaccaat
    14221 accttcaccc atcgaaatcc caacagcttg tgaagctacg cctgttgcaa aaggatttac
    14281 cgttgaagct agacagccta cttgagaccc tactaatacg attgctacag ctactactgt
    14341 atcaaagcct acagccatca tgactgggat cagtaaagca tagaatggaa tcgtttcttc
    14401 tgccattccg taagtagagc cgcctaatgc aaataacagc atcaatactg gaataagcat
    14461 tttttctttt cctttgaatt tcttcacaac tgaagcaatc ccggcatcta gtgcccctgt
    14521 tttgttgata atacctaaaa atccaccaac aaccaaaatg aagaaagaga ttgggattgc
    14581 agcaggtgtt tctttagtta gctcccccgc tggtacacct agcatcccat tgattggcgc
    14641 catgaaaata tcccacagcc cttgaggatt ttgttgtact cgttcatatg atccagcgac
    14701 gatgttgcct gcatcgtcta cactatagtg cccagctggt ataaaccaag taagtacagc
    14761 gattactgca ataataataa ataagaccgt atacgctgaa ggcatttgaa attttttctt
    14821 ttttgtttgt tccatcttct tcttcctttc ttttccgtta gagacaacaa ttttggctct
    14881 aatgttattt tatcaaaaag agtatcagaa caaaaataat aacacgcatt ttgtaaaact
    14941 tttgttcaaa aagttcgttt ttccctattc cctcctcttt tttcaggttt ttaaagcttt
    15001 cttctttttc attgtagcgt ttcctttttt ttataaacaa acattttcgt cttttaaaag
    15061 gagaagaatt tcacatttgc aaagaattga ttgattttta tgcataaatc aaaaaaatac
    15121 tcaaaacaaa caaataaaac gtttacatta ttgcatgtct tgtatttttt tccaaaaaaa
    15181 aagaccaaga aatttcttga tctttttgat atttatttga ctgctgtatg acgttgttcg
    15241 aactgatgtt gttttcgact taaccatgga agaagttgcg catgcagcac taaaaagaca
    15301 gcactcacga tgaatccttt gatcaagttg aaaggaacga tcccaatcag tacatagttt
    15361 gctaaagaca tgcccagcat ctgtgttgcg ttcagcccta aaaacattaa gtaaagaggc
    15421 gtaataacga aataatttgc gatactcata aaaatagtta gagcgatggt tcctgtaatg
    15481 acacctaaaa atttgtttct tcctttatgc tgtttcttta cactaaagaa ataataaatc
    15541 gggaatgtaa agatcgttgt tgataagaaa ctagcagtgt ctcctaccaa attatccgga
    15601 gaaaaacctg tagtcagcag atgtaatact gaacgcaaga acgctgttgc aactccggcc
    15661 gctggaccga ataagaacat gctgatcaat accgagatat cactaaaatc gatcttcaaa
    15721 aaactaaaag ccggcatgat cggaaaagca aaatactgta aaactaatgc gatcgcagca
    15781 aacatcgcta ctgcaaccat tttctgtaca cgggtgttct tcatttgaaa tcctcctgtt
    15841 aggactcctc ttcagcgaac tttttgacgt ttctctccaa atgaaaaaac tctattttcc
    15901 agggaaaata gagttagagt tatttgatca agcgtcgtca aataagctct atcttcttta
    15961 tccagactat actgtcggta tcggaatttc accgattcag ctattttttt gcaaaatagg
    16021 tcgtggacta taaccaccgg tcgggaattt caccctgccc ctgaagacga accttatata
    16081 atttttgttt acatattcat tatacatatc tattcaaaaa acgcaacatc taacacttat
    16141 aaaaagtaag tgttcatttt gagtggttca gcaaactgct gacttctttt ttgttcagtt
    16201 cacggtaatc cccaggacgt aggccttgta aagtcagatc tccgtatttt tcacgtttta
    16261 gtttttgcac aggaagacca actgcttgaa gcatattttt cacttgatga ttacgtcctt
    16321 cgtggatcgt caattccacg atactgtggt ttgtcttagg atccactgat aaaatttgga
    16381 atttagctgg agatgttttt cgtccttcga tctttattcc ttttgtcaaa ggtgcaagca
    16441 tcgattttgt agcgatccct tttacctttg caacgtaaac tttatccact tcatgttttg
    16501 gatgtgtcag gcgctgagca aaatctccat catttgtcag tagcaagatc cccgaagtat
    16561 cgtaatccag tcgacctaca ggatagatac gttcttttac catcggcaaa agatccgtaa
    16621 caacttttct tcctttgtca tctgcaacag cagaaataac tcctttaggt ttgtacaata
    16681 aatagtaacc gtattcttct tgataaattg ggacttcatc cacttccaca gtgtcatgtt
    16741 tcccaacttt tatccctaat tcccttacaa cttgtccgtt tacttttaca cgtcctgcaa
    16801 ggatgaattc ttctgctttt cgacgagaag tgatgccagc gtgggcaatt actttctgca
    16861 atctctccat tacaattatt ctcctttatt cattccatca aagaatagat ctggtgacac
    16921 gtcttcttca agtgaaattt ccatttcttg tgtatcaggc agttcttcta atgatttcaa
    16981 accaaaataa tctaagaagt agccagttgt tccatataat atcggccgac ctggtccttc
    17041 tactctacct ttttcttcaa tcagtttatg ggcagctaga cgctgtaccg ctcctgaaac
    17101 ctgaactcct cgaatctgct cgatttcagc tcttgtgatt ggctgtttat aagcgatgat
    17161 tgctaaggtt tcgacggcgg cttgagataa tgtgtttgat gtcccttgcg catatcgctt
    17221 aagtaaggga gccagctctt ttttagtcgt taatacataa tggctttccg tttcaaaaat
    17281 atgcaaagct gagtgcgagt tttgagtgta agattctttt aattctttca ctaaacttgt
    17341 gacttctgct tcgctgagat ttaacagtcc gcttaattct tcattactga tcccttcctc
    17401 gccaacaata aaaagaaggg cttcaagttc acttaatttc gtcatgttcg gtatctccta
    17461 ctgctggata aagcataatt gattcatagt tttctttttg ttgcgcaatg atctgccctt
    17521 ttttcatcaa ttctagcaaa gccataaaag tagtgacaac ttcactttta gaaggtgact
    17581 caaaaaaaga atcgaaagta cagccatgcg catttctttt tatacgctct tcgataaata
    17641 ccattcgttc ttcgatcgtt gtgtcatcgg gcgtgatcgt tttttccact ttttgagaaa
    17701 atttcttacg ttctaagatt ttctgcatgg cacggatcaa atcgattttt ttgacttgtc
    17761 ctcgcttcaa cggcttttca gcatccgcta acccatcgat gttcataggt tcttttgtgt
    17821 aataaagact tcgttcctct gctttttctg tcagtctttc agctgcatat ttatatttac
    17881 ggtattctaa aagctgagtg accaattctt ctcgaggatc ttcttcccat aattcttcat
    17941 cgtctgtgac gaattcttgg acaggaagca atgtcttgct tttgattgcc atcaatgtag
    18001 cagccatcac taagtattct cctgcaacag ctagctcgag tgttttcatt gtatggatat
    18061 aattcatata ttgctccgtg atcgtagcga tcggtatatc atatatatcg atttccattt
    18121 gctgaatcag atgaagcagc agatcgagag gaccctcgaa tacatctaat ttaatattga
    18181 tctccgtcaa ctcattcact ctttcttctt tttctttgct agccattttc caatgtaagg
    18241 ctctgtgatt tcagttgcac ggatggagac atccgggtac ttttcctgta attcatctaa
    18301 catttgaaag cccatattct caccgcgata agacggattc aaagaaatgt catggatgat
    18361 cagctgatcg ttcgttgccc agtaaatacc aataatccct tgaatgttgg ttgaaccttc
    18421 tggcgtaaag aaaaaaagtt cataatcgtc ttcagattcg tacgtatcaa tctccttcaa
    18481 caaagaagtt ttacctgtca gtttcttatg gaaactcaat agtcccatag caattttacg
    18541 gttttctttc cggtaatgtg ttaacatctt ctcaccttcc tatgactaag cccttggaaa
    18601 atgctgctta taaacatccg tcattctttt cttcgtgata tgtgtataaa tctgagtcgt
    18661 agagatatcc gcgtgaccta acaattcctg tactgtccgc aaatcagctc cattttctag
    18721 cagatgtgtg gcaaagctat gccgcagcgt atgtggtgtt acttctttgt aaatcccagc
    18781 ctctcgtact aactgcttca gatttttcca gattccttgc cgagaaagac ctttcccatg
    18841 attattgaca aatacatgca tttcagatgc gtcctttaca agtaatggac gtgcttcgtc
    18901 taagtagcgt tccagccatt ggatcgcata atcacctaaa ggaatgatcc gctctttatc
    18961 tccttttcca actgtctgta ccagtccaag agaaagatga agatctccca atttcaatcc
    19021 aatcaattca ctgacgcgca tcccagtagc atacatgact tccaagattg cacgatctct
    19081 tatccctaac gtttttgtcg tatcaggtgc ttcaatcagc ttttctactt ctgtcagagt
    19141 caatgtactt ggtaatttct gtgctttctt cggcgtatcg atatgttgca tcggatcatg
    19201 atcagtgata cgctcttgcc gtaaaaactg atggaatctt ctgagacttg agatcatccg
    19261 agtaacagtt gctgtcgctt ttttttcttc atgcaacttc tccagaaaac ggatgactaa
    19321 aaagcgatcg acatcctgcc atgaagcaat tttctgctcc tgtagaaaat gcaagtactg
    19381 ttccaaatca cgttcatagc tttgtcgtgt attggcggac aatccccgtt caatattcaa
    19441 gtagtggaga taatcgttga tttgctcttt cataataatc cccctcatgc ctctctatca
    19501 tatcagatac cgcttcattc tgatagtctt tttccataat ctgagcaaag aaaaagccgt
    19561 ctagacactc agacggactg gtttcttttt tctttttcat agcattcctg acagattcca
    19621 tggaacgtta gccgatgatc ttttactaaa aaatgataac gttcttctac tacttgctcc
    19681 acttcaagta aaagatcctc ttctacttcc tcgatcgtgc cgcagttcaa gcatagtaaa
    19741 tgatgatgga aatgtttggc gccttctttt ctcaaatcat aacgggctaa tccatcatta
    19801 aaacttactt tatcgacaat tttcaattct gtcaagattt caagggttcg ataaacagta
    19861 gcaagtccaa tttccggact cttttttttc actaaaaaga agatttcttc tgcagataaa
    19921 tgctctttct cattttccaa aagcacaagc agagtagctt ctctttgcgg tgtcagctta
    19981 aaccccgctt catgtagctg ctgttttgtt tttttcatcg ccgaaatagc attcatgacc
    20041 atttactcaa ccccaacaat ttataataat tacaaataaa aaaagatata acactatgtt
    20101 aattaaaatt attataagct agttaagaaa aacatgcaag ggattctcaa ttagattttt
    20161 tgactagttt tgtcacaccg ttttcttgtg taatcaatcc ttgtttcaaa agattaccta
    20221 atgcgcgctt aaatgctcct ttgctgatac caaaagcttt catgatttct tctggatccg
    20281 atttatctgt aaagttgatt tgctgatctg cagaacgttc taaaatggtt aaaatcattt
    20341 gtgcatcatc tgatatagct tcatatgctc ttggcttcaa tgaaagattc agtacaccgt
    20401 ctggtcggac accaatcact cgacctttta tctgctcgcc tagacgaggt tcattatatc
    20461 gttcagaagg atggataaac ccaagataga aatcttccgt taaaacgtac gtacctgtta
    20521 atttcaagcg gtatgctgtt cctatcacat ctttgttttt catttcttct gttccatatt
    20581 tgcttaaaga tttgaatatt ttttcatctg ctaaactgcc ccaaatacgg tcttttgcat
    20641 caactctaag ggaaatcatc aagcgatccc cttttttagg ccatagctct gtcattgtcg
    20701 gcaattcatc aagagatacg acaaagtctt tatctggaag accgatatcg acaaacgcac
    20761 ctaaatcttt tcgtgtagca gtaacgattc caaaaccgta atgaccgata cggcttttag
    20821 gaatttgtgt agtgatccga ttttcatgtt tttgattttg gtaaccgaat ccttcaactg
    20881 cttcaccgat tttgtgttca ccttctgatt tgcttaagcc aaaggtttgt ccgttttttt
    20941 ggacaaagta gtttttttca ttttcatcaa taataatacc tgtaaatata gttgctaata
    21001 aatcgttcat ttttttctcc ctctatagtg aaaggttttc ttaatacatt tctttgctat
    21061 cataacataa tgttatctac ttgaatagct gagccttggt ttggaaaggt gaaaaaagga
    21121 gtatgacaac agttgtgtca tactcccctt tttcgaataa acggtgttaa acggcaggct
    21181 cacagcctct ttcatttgcc taaaattaat tgctcccatt tcctccgaac catccagttt
    21241 tacagttgat ggttacgatg taaaatggca aagcactttc tccaatgcct ttcatcaatg
    21301 cagattttgt tgaagtggca tatagattat aatagccttc cccattttcg attctggctt
    21361 tttctaatct gtaacctcct tcaacgatat atccacgttg gatacatgta gcaatcactt
    21421 tgctttggac acctggtgcc cacgtccatg ctggattaga tgcatcggca atatcacttg
    21481 ctctggcaga tttgattggc tgattcgctg agtttgaaga ggaaggggtc gaggatgccg
    21541 cttcttgctg tgctgcttgt gcgaccgcag cttgttgagc ggcttgagct gcagctgctg
    21601 cttgagcggc ttgttttgct tgttcttcag ctgctttttt cgcttcttct gcttttttct
    21661 tttcctcttc ttcttttttc tctttatcag tgagcatctt atctacttgt ttcaattgtt
    21721 cattcaactg agcagataga tctgtatttt tcactttttc tactgcttct tttgccgtct
    21781 tgtattggtc gcgtgttgct gaatccacta cttttccgtc tttaaagact atagctgttt
    21841 tttctttagc tgtttgcaat tcagcatatt gatttttagc ttctgtttgt gcttgttgaa
    21901 tcaattttcc aaaatctgtg ttatccgttt cgattgcttg gatctcttta tctgctttca
    21961 acttgatgtc atctgctaga tgatcatcga cgatggcagg tgctatgaac cactcattca
    22021 ctttttggat atctcggatc ttagattgga tatcttggta agttgtttct aactctgaat
    22081 atcctttttc attcttaaga ctggataaat cattttttag ttttgataaa tcttgatgaa
    22141 tcatatctgc acgaataaat tgatggtgat catctgtata aaaggcagca agtttctcat
    22201 gaagttcttc catttgttgc tgtctttttg cttctgctgc tacttcggct tctacttttt
    22261 gatgatggtc ataataagcc cagcttcctc caccgagtag aagtactgct gctaaaacga
    22321 gataaggtac tttttttgat tttttctttt gcgctttatc tggatctgtt ttttctaagt
    22381 ttgattcttg atgtgttttt tcagtatctg gcacgattgt tattgatttc gcttctgctt
    22441 caaacagctt aggctggttc tcttcttttt ctatttttgc ttcaagatca gtaccctctt
    22501 tgcttacaga ttgattttca gcatcggatt cactatttat ttcatcgggc tctgttgact
    22561 ttttgtctgt gttttcgagt atttcttttt tctctgcttc cggcagttta ttcgtttttt
    22621 ccttttctaa ttgtttttca gtaaatactt cagttttttc tgtgatatcc gtttttacgt
    22681 cttttatttt tactgtttct ttacctgtgg cgttttctct atcagagtct ttttcagttt
    22741 cttgttcctt ttctggctct actttgtttt cctgtgcaat tttttcactg atcattttga
    22801 gcagctcttt cgcgtgctct tcttttgtat cttcacgatg tgctttgata taagcggata
    22861 gtatcgaatt ttcttcctca ttatcgacga tttctttcag ttcagctact cttctttttt
    22921 gttttgattc aagcgtttct tcttgattct ttcctgattc ttccgaagtc tcatgaacag
    22981 ttgctttctt ctgttcattt ttctctatat tagttacttg atcgtgagca ggtggttctt
    23041 cgtcttctgg ttctgctttt tcgaataatt ccattacaga ttctagaggt aaatctttca
    23101 attccgacca ttcgattgga tcgtttaatt ctgtatcagg aaagactgca tcttcagttg
    23161 atttatcctg catagctgca tctgtatttg tttcttcaat tgattctttt atttgctgat
    23221 cttctgcagt tatttgatga ccgcagtctg gacagatagt attctgctcc atttttttcg
    23281 atccgcaatt tggacatttt ttcatcactt agcgatcggc tcctttacta ggtttacgct
    23341 accatttaat ctatcatatt ctatacgtca cgccaatagc ttatttttag gatttactta
    23401 aaaataatga atgaatttcc ttcctataga aaaaaaagct tgagactgcg tagtctcaag
//
LOCUS       DAYNVV010000042        22463 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.042, whole genome shotgun sequence.
ACCESSION   DAYNVV010000042 DAYNVV010000000
VERSION     DAYNVV010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22463
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.042"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            144..542
                     /locus_tag="ACGXWR_001862"
     CDS             144..542
                     /locus_tag="ACGXWR_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFK0803418.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            526..1221
                     /locus_tag="ACGXWR_001863"
     CDS             526..1221
                     /locus_tag="ACGXWR_001863"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HFK0803419.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1815..2702)
                     /locus_tag="ACGXWR_001864"
     CDS             complement(1815..2702)
                     /locus_tag="ACGXWR_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HFK0803420.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2887..3726
                     /locus_tag="ACGXWR_001865"
     CDS             2887..3726
                     /locus_tag="ACGXWR_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFK0803421.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3922..4896
                     /gene="sgrA"
                     /locus_tag="ACGXWR_001866"
     CDS             3922..4896
                     /gene="sgrA"
                     /locus_tag="ACGXWR_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HFK0803422.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5194..5550
                     /locus_tag="ACGXWR_001867"
     CDS             5194..5550
                     /locus_tag="ACGXWR_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803423.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5595..6710
                     /locus_tag="ACGXWR_001868"
     CDS             5595..6710
                     /locus_tag="ACGXWR_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803424.1"
                     /translation="MKNYHLSCSLKKGNPIEGEEYRIRYFFHLMYWQSFDENHSDILS
                     SIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSITYVPEEMNKFVHPL
                     ITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYLEEDLLDTPDKVQES
                     WGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGTKKKVDAFGKSAEDR
                     DFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCMLVRDIFIKHEQPVIF
                     YIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYPIDKKAYDQTNTQIF
                     YWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6736..7176)
                     /locus_tag="ACGXWR_001869"
     CDS             complement(6736..7176)
                     /locus_tag="ACGXWR_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFK0803425.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7336..7842
                     /locus_tag="ACGXWR_001870"
     CDS             7336..7842
                     /locus_tag="ACGXWR_001870"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFK0803426.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            8010..9922
                     /locus_tag="ACGXWR_001871"
                     /pseudo
     CDS             8010..9922
                     /locus_tag="ACGXWR_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
     gene            9927..10928
                     /locus_tag="ACGXWR_001872"
     CDS             9927..10928
                     /locus_tag="ACGXWR_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFK0803427.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(11130..11336)
                     /locus_tag="ACGXWR_001873"
     CDS             complement(11130..11336)
                     /locus_tag="ACGXWR_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HFK0803428.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11982..12830)
                     /locus_tag="ACGXWR_001874"
     CDS             complement(11982..12830)
                     /locus_tag="ACGXWR_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFK0803429.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12994..13896
                     /gene="gnd"
                     /locus_tag="ACGXWR_001875"
     CDS             12994..13896
                     /gene="gnd"
                     /locus_tag="ACGXWR_001875"
                     /EC_number="1.1.1.343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydrogenase
                     (NAD(+)-dependent, decarboxylating)"
                     /protein_id="HFK0803430.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            13898..14899
                     /locus_tag="ACGXWR_001876"
     CDS             13898..14899
                     /locus_tag="ACGXWR_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="HFK0803431.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14896..15180
                     /locus_tag="ACGXWR_001877"
     CDS             14896..15180
                     /locus_tag="ACGXWR_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HFK0803432.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15213..16010
                     /locus_tag="ACGXWR_001878"
     CDS             15213..16010
                     /locus_tag="ACGXWR_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFK0803433.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            16024..16857
                     /locus_tag="ACGXWR_001879"
     CDS             16024..16857
                     /locus_tag="ACGXWR_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFK0803434.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16875..17732
                     /locus_tag="ACGXWR_001880"
     CDS             16875..17732
                     /locus_tag="ACGXWR_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFK0803435.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17754..18263
                     /locus_tag="ACGXWR_001881"
     CDS             17754..18263
                     /locus_tag="ACGXWR_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFK0803436.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18300..18701
                     /locus_tag="ACGXWR_001882"
     CDS             18300..18701
                     /locus_tag="ACGXWR_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803437.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18813..19166
                     /locus_tag="ACGXWR_001883"
     CDS             18813..19166
                     /locus_tag="ACGXWR_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803438.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19200..19643
                     /locus_tag="ACGXWR_001884"
     CDS             19200..19643
                     /locus_tag="ACGXWR_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFK0803439.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19660..20745
                     /gene="uxuA"
                     /locus_tag="ACGXWR_001885"
     CDS             19660..20745
                     /gene="uxuA"
                     /locus_tag="ACGXWR_001885"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFK0803440.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20738..21451
                     /locus_tag="ACGXWR_001886"
     CDS             20738..21451
                     /locus_tag="ACGXWR_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFK0803441.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(21658..21807)
                     /locus_tag="ACGXWR_001887"
     CDS             complement(21658..21807)
                     /locus_tag="ACGXWR_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803442.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            22203..22403
                     /locus_tag="ACGXWR_001888"
     CDS             22203..22403
                     /locus_tag="ACGXWR_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFK0803443.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         7745 a         3451 c         4643 g         6624 t
ORIGIN      
        1 tccatacatc cattgtactc tgagaaatca cacaatatcg aaacaaattc cgttaggaat
       61 gtgttattca ataaatttta taatctagaa acattttgaa taaaaactat tagacaaatg
      121 atattttacg aggaggaaca gagatgacga tctttgaaac ggttgtaaca gatgttggta
      181 tagaagcaga agtattcagg aaagaaaaaa taatgatttt atttggagat gaagcaccgg
      241 aaacattaac agattattgt tataagattg aattgaatca ggtaagaaaa gaaataactt
      301 gtgatatgaa gctctgtttt gataaacaaa tgtatgtaat cacagcagta ggagatgttg
      361 tccaaactaa tttgaatgaa ttaggacata tcacgataaa atttgatgga tctcatgagc
      421 cggaacttcc aggaacaatg tatgtagaag ataaggaaat gccgcattta agaaagggga
      481 caatcattaa aatcgatcaa gaggatcaga atgggggaaa gctatatgga aatcatgctt
      541 gatacagcaa atacaaaaag tatttattct tgtcaacagt ttttgaattt aacaggcgta
      601 acaacaaatc ctacaattct gaaaaaagaa ggagcgtcaa acttcttctc gcatatgaaa
      661 gaaatcaaaa aaataatcgg acagattcct atccatattc agacaatagg aagaacggaa
      721 gaagaaatga tagaggatgc tcgagttatc atagaagaac tgggaaaaga tacgtttatc
      781 aaggtgccgg tgaatcaagc aggccttcaa gcgatcaaaa agttgaaaaa agaaggttat
      841 ttgattaccg gtacagctat ttacacagaa ttacaagggt atttagctat taataatgga
      901 gcagattata ttgcacctta ttataacagg atgcaaaatc aaggcattga tgctatgaaa
      961 gtgattgatt cgttgcggac tgagatcgaa cgtacgcaaa gaccaacaaa aatattagca
     1021 gctagtttca aaaattgtga acaagtcact acagccattc gatctggagc tcatgcgata
     1081 acgttaggta aagagctact agatcaagta ttagagatgc cctcgattga taaagcagtg
     1141 aggggcttcc aagaagattg ggtgcaaact ttccaagcag aaacgattgg tgaactaaaa
     1201 aaggtcgctg attacttctg aatcaatttc tccataaaat aaacgatagc cttctcgaaa
     1261 actcgaggag gctatctgac gattcaatat tcattaattt aaagtttggg tgactattac
     1321 taactattac ttatttctca tttaaacgat gtattcccta acctctaata catccttgta
     1381 actctgaagt tacgccagtt ttgaataaat ttcataaaaa caaatgaaaa gtgtcgcata
     1441 aaaatatctt tcgtgtttct ctagtataac agaataagaa gaacaagtcc agaagggata
     1501 tttttagtct tttttaaaat aacttttcag tcgagtttga gtttatgata gttgtttttg
     1561 aagcgatacg gcaagtgaaa aaatagggaa gcatgaaaga atctacttaa tggcgcattg
     1621 attcatgtga tagaaataaa aaactttttt aaattatatc ctcatgattg taacaaatcc
     1681 agtgatttgt tttggtacaa ataaaaaaag gccccgatga agttgtggca aaagtggttt
     1741 gcctcaaaaa taagaaggaa tttccaaaaa tcacttctca aattttgcca catccccaat
     1801 tgggtcaaat ttgtttattt gaatatattt tttacataag gatctttaat agttacattg
     1861 tcttttttca tcactttacg gattgtttta tccatgaatt ccgtatcaag agtttttgct
     1921 tcggtagcaa ttttttctag ctcagatttg tatttgtctt tattagaacc tttatcctgt
     1981 ttttttacca tttttactag ataatagctt tgctgataag tcgttggatc tgttacagga
     2041 atgatatcag aaacttcccc gttttttagt ttaaatgctg ctttttttac ttcagtagga
     2101 atctctggat tggttgaatc aaaattcatt tttccatcag tttcctttaa tgttttattt
     2161 tttccataag cttgaacaag cttggagaaa ttttctcctt catttgcttc tttttttgct
     2221 ttatctgctt cttctttagt cgaaaataga atgatctgtg tactaacttc tggatagaat
     2281 tctttccaag cagtgtctag atctttatct gttaatttta cattggcttt caaaccgtat
     2341 tggaaagcca gcatctgttt aaagagtttc ttatatgtct cttctgtttg gccaactgct
     2401 tttaattgtt ccttgtagtt tggaccgagt tttttgattt gttcattata ttcttttgtt
     2461 acttcctttg aagaaatctc ttttccgtat acatcatcaa atgctttgaa gacaatcatt
     2521 ttttttaata gtgtttgatt atttgattta acttttgggt tatcataaaa atcctgaact
     2581 gtaagtgttc cacctttaaa cgttgcaatc gtttcattgg acttgctaca acctgagaat
     2641 agtaaaattg cacatgctga aaggcacata attagtagtt gttttttcaa aaaatttccc
     2701 atcctttcct tattaaaaac agtctaacag aagaattagg gagacagtct ttcattttcg
     2761 taaggttgct gtagatattc ttagttcgta aaaatctatt ctctctatga tggagaacat
     2821 ttacatagtt ttcacgagac aagaaagaaa agggttgtta aacttaatat aaaggaggga
     2881 tgaaagatga tcaggattat tcggttgatt ggatctgttt taatagtctt agttggtttt
     2941 gttttaggaa ttcttgtcaa taatgcactt gcggatatgt ttattggaaa tagtgaatgg
     3001 attggagcaa ttgccggtac ggtcggacat ttagctgttt ttttactagc tttatttctt
     3061 gctagtaagg tcgaaggaaa aagaatagaa gattatggtg tttctgttcg aggaaaagac
     3121 tgggggtatt tagcgggagg tctcgttgtt ggaattggag tgtttctgct tattactagt
     3181 ccattatatt tgacgggggc gtatcggtta gattcaggaa acgcaaacat tgtgccgctg
     3241 ataacgagtt ttattttatt tattgcagtg ggggcatcag aagagctttt attccgtggc
     3301 ttttttcagc atcagatgct tagatttggt ccgttaatag caatgattgg atctgctgca
     3361 ttatttgctc ttttgcacgg attgaatcct aacatgacat ttctggcagt tttcaatatc
     3421 tttttagcag gttgcttttt cagcgcactt atctacagta caggaagttt atttacggct
     3481 attggtgctc atattacttg gaattggaca caaggagcta ttttgggtat accagtcagc
     3541 ggaacgcaag aacaaggttt tttctccact ctgatccaat cgcaaaatac aataattact
     3601 gggggaaact ttggggctga agcatctata tcaactacat tattcttgtt agtcttgatt
     3661 gttggtttgt tactctatgc atataaaaca aagcggatga agaaatacac tgctgtttat
     3721 caataaaaga tgaagaaagc aaggctgata tcggtcttgc ttttttaagt ctgtcattga
     3781 ttaaacgaaa aagtaaacaa attcaagcga atacacgaca tcttttgtta gattttcaca
     3841 actgactgtc gtgttctcat cattttcatt ttatataatt cctttatcaa atagaaggta
     3901 attatatgga gagtgataga aatgaagaaa acagcgaccg tattatttgt tattcttggg
     3961 ctgagtataa ttgcagcaat gattggaatc agtacttctg caaatgaacg ggcaaatgag
     4021 aatctttcat ttactgtgaa aactgatcgg attgtttatg acatgacaca acaagtcatt
     4081 actattccag tcaaaccaaa caaaagcgtg aatgctagtg atgtacatgc tgttctaaca
     4141 tatggttggg atggtaatgg aagttcagaa aaagttattg gggaagttta tttaaaagac
     4201 gtacaatgga ccgctggtat tgagtataca ataatgattt ctgcagaact atcgattgat
     4261 gagatcaaga gtaaagataa agttgatttg attgtttttt atgatggaca gatgacgatc
     4321 acggagaatt tgaaaccaag cagttggaca gttgttggac cgccaagcag tacggatagc
     4381 acaagtagtg aaagcagtac agaaaacacg agcggtgaaa gcagtacaga gagtacgagc
     4441 agtgaaagta gcacagaaaa cacgagcagc gaaagcagta cggagagtac gagtagtgaa
     4501 agtagcacag gaagcacgag cagcgaaagc agtacggaga gtacgagtag tgaaagtagc
     4561 acaggaagca tgagtagtga gagtagcaca ggaagcacga gcagcgaaag cagcacagga
     4621 aaagtaaata atgaacttga tttggtacct atcataccaa ctaaggaaca aaagagaaat
     4681 gcagggagca acctaaaaag tgtgctaaaa cagcctgatt ttgtttctcg tggaattgat
     4741 catcaagaaa aagcgaaaga aacagataat agaaaaagcg atttaccaga aactggtagt
     4801 agaaccttga acaagctaat tacatggatg ggtgtgttac tcattttgat tgtaggagca
     4861 agctattttc gttctctctt ccatcgagtg aaataaagaa taaaagcaac agatctaaaa
     4921 ttgaataaaa cgatagattt ttgagtgaat atttcattcg agagtgctgt attgcctggc
     4981 gaagttgtag ctttgccaga tctatttttg tttactaaca tatttgagaa acaggaaata
     5041 acaggaacac aaatggaaaa taagagcaag aataattgac aatgcacact gcgcatggta
     5101 gtatctctga aaaatcagta acgaatctat ttgtacgtta ttcatgtagc tgtcggaata
     5161 agtctaaata atagataaaa aggagtatgt actttgtttg aagaatttat tgatatcaat
     5221 gaaaggcaag tatatcaatt tttgaactat tgttatgaaa gagacgagaa attatatgtg
     5281 gtgaaggata tcgctttaga tctaaactac accctggcta agatgaattc ggtgattcaa
     5341 caagcagaat cgttttgcga aaggtatcca gaatataaat tatcttttct ttcagaaaac
     5401 aagatgataa aagtcgagtt ttcttctcag tttttactga gtaaagttta ttctatactt
     5461 ttagagggaa cgattggtta tattttactg gattcacttt acaaaggtac ttatcaatcc
     5521 ttagaaaatc ttagtcaaaa aattatataa gtttgcgtac gattcaaaga aaattaagag
     5581 aacttaatac tattttgaaa aactatcatt tatcttgcag cttgaaaaaa ggtaatccga
     5641 tagaaggaga agaataccgt atccgatact tttttcactt gatgtattgg cagtcattcg
     5701 acgaaaatca ttctgatata ttatcaagta taaaaaataa acgtcaacta ttagaaaaat
     5761 ttgcgaaaca tgcgccatat acgcgtagta tagatagaaa gaaatggatc agcctactaa
     5821 gaatttcgtt gcaacgaatg aaacaaggcc actcgattac gtatgtccca gaagagatga
     5881 acaaatttgt gcatccattg ataacaaaag aagagtttac gcattacata ctagagcctt
     5941 tttttgaagc aaacttctgg tcgatgaatc acatcactcc aacagagcaa gcttaccttt
     6001 attttatgtt tggtgtaatg aacacctatt tggaagaaga tttgttggat actccagata
     6061 aagtacaaga aagttggggc tggattgaat cgtctattgt agaaaatttt gaaaaaaact
     6121 tcaagatttg ttttacaact tcagaaaaaa attatctata tgtcaatttg gcaatgatcc
     6181 atttgtattc aagggttttt gggacaaaaa agaaggtgga tgcttttgga aaatcagcag
     6241 aagacagaga ttttcagcat atatttccag tgatgtatcc aatcatgcaa cagtttttta
     6301 gtggggtagc tcgcagaatt ccagagctta atacttatta tgaaaagaac agacggttga
     6361 tttttcaata ctgtatgtta gtcagggata tttttataaa acacgaacaa cctgtcatat
     6421 tctatattca atcaaagtat ggtaaaacac aggaattatg ggcaaagaaa aggatattat
     6481 ctatgactga acgcccaata aaatatagtg catccgctga tcagttacct gatattgtca
     6541 ttagcgatta tcctatcgac aaaaaggcat atgatcaaac gaatacacag atattttact
     6601 ggaatggaca acctacaaaa aatgattggg cgcgtctgaa agctgaaatc ataaaaatca
     6661 ggaatgagaa aaatagatcc atattggaaa aattggattt cgttaattaa gaaaagcaga
     6721 ttgtttatgc caaaattaag acattgcaaa aagattattt tctttaaaat cgacaagatg
     6781 accagaaagc aagagttcgt tgagctcttg ctttctttta gttttagaaa ggaacatcct
     6841 gattttatct tcgctaaatc cagtcaaaag ttttgcagat tggtcgtaga taatcggttt
     6901 tttcaataaa gaaggggatg tacgaatctc aatatatagt tcactcaaac tgagttcatc
     6961 tattctgtga acaagatttt tataactaat agaatgagta gagagcattt cggtcacgcc
     7021 gttgtttgtc aattttagta agtggataaa ttcatttttg gttagtggtt gacgaattaa
     7081 gttctgttcg ataaacggta tatcatggac gataagccaa cgttttgcgc gtcttgaaga
     7141 cgagcagcca gaacctgtat acaatttaat catcatacat tcctccaata gctaagtatt
     7201 tatgaaataa taacatgaag aaatagtcga aaagtgccat ttagaggtgt aaaataagaa
     7261 aatgttgtca cgtataatgg aactagctag ataagaaata ctattaaatc aagaaaaaag
     7321 aaagaaggca caagtatgtc aaacacagcc gacgcaatag tagtgatcga tttacaaaaa
     7381 ggggtatgtt ttgattcttc gccgatacac gaattagaaa cagtgacagc attagtgaat
     7441 aaaagaatca aaacatacga aacgattggg aaaccagtta ttttcgttca acacgaagat
     7501 gctcaattag tgccacaaac aaaaccatgg gagctattgt cggaattatc tattcctgag
     7561 cacagttatt ttgtgagaaa aacccatgcg aattcatttt ataagactaa tttgagtgtt
     7621 ttattaactg aattggactg tcattcgatc gaattatgtg gggcacaagc agagtattgt
     7681 atagatacga ctgtgaagtt tgctcatgga ttaggatacc agcttatgat gtgtagagga
     7741 gcaacgacaa cttatgataa tccttttatg aaagcaaagg aaacaatcgc tttttacgag
     7801 aaaatttggg ataaacgatt tctgacattt ttggagcaat aagttgtttc ttcgtttaaa
     7861 aaaagcagaa tggatactgg tttatccatt ctgctttatt acgtaaaatg agaaaataat
     7921 cctgttctat ttttatggga taaaccattt attttttgta taaaaaatgt ttgcgtttac
     7981 atataattct cctagaaaca taaaaaggag tgaatagctt gagaacaaaa caagtattaa
     8041 agggagcgtt ggtcatctta tttgctgtaa gtacaagcgt cccgcaatgg acagtatatg
     8101 gagagagcat ttcttccgaa tcggaatctc gggaggtaga aaccacagaa actactgatg
     8161 ctggaaatga aacgaaatcg agtacttcac aaacagaaac aaatactgaa acaacggttg
     8221 agacatctgt tactagcaca gatcaagaaa cgaccgctac cacagataac caacaaacag
     8281 aagaagcaac agctacaaaa atgtcaaacg acgaatcctc ttctgctaaa gtaagtgaca
     8341 aagagaatgg gacagaaaat gatgatatcg gtaaaggtga aaatttcaat ggtaaagaat
     8401 atttgaatta cttcggtaaa cagatgacag aaatacttaa tggaccaaca gaagacatca
     8461 agtcaaaatt aatagagtta ttagtcactg agcttgctgt taatgattat ggtgtagata
     8521 aagagattat caaacatctg attgctactt atctattgta cgatatcgct tttgcaaaaa
     8581 acagtgtgtt gatgtcgatg cttggaggta cagatgatgg gacaacgcct acagaaaaca
     8641 caggcttcta tccaaataca aaacaacttc atcaaactgt actaaacaaa caagatggca
     8701 aaatgatgga tgtatatgca tattatgtcg atcaaggttc agataaaaca gtcatgatcc
     8761 atggcggatt tcgagggaat tggaataacg ggatcgttac agaagaatac aatgattttt
     8821 ataaggccgg gtataattta ttatttgttg attccagagc gactggtaat agcggaggcg
     8881 attatgtgac ctatggacaa tatgagtcag atgacgtcct ttactggata aatcaagaag
     8941 ttcgagagcg gccatctcaa aagattttac tttatggtgg ttcgatggga gcagctacga
     9001 tgatgtctgt attagcgaaa gatattcctg tcaatgtcaa aggaattatt gaaaattgcg
     9061 gatttgcatc aattgatgaa caactacgtt ttacgtacag ccagacagta gcccccgcac
     9121 taccggatgc cataaaaaat cagttagaca tcattgggga tcaagagcat gaagatttat
     9181 ttatgggcct tttgaaacaa tactattttg atcaggagat gcatttggat acaaaagctg
     9241 ctctacctac gattggaatg tcagattcat tgcctaaatt gattatccat ggaacagcag
     9301 atgatgtagt acctgtgtct aacgcgcaaa aattatatga gttatcagga gggtataaag
     9361 atcttttatt agtagaagga gcagggcatg gaaaggcaca ggaagttgac catgctgcct
     9421 acacgaaaca tgtaacggac tttttgaaag tagtgttcca tgatcagata aacgtaaagt
     9481 atgtggatga aaacaataaa agtctactca aagaccagga cgaaatccag ctttacggag
     9541 cttatggaga aaattatatg acagagcaaa agacattcga aggatacgaa ttagcaaatg
     9601 ttgaaggacc gactgaaggg atttttaatg agacgatacc aactattatt ttctattaca
     9661 aaaaaatccc agtagctcca ccaaaaaagc aagatccgac agagaatgca gacaataagg
     9721 gaaagaatga acctcgagag gatcaatcaa gtgatgatac gcaaccgatt cagatgacag
     9781 tgaaagtaca aaaaaagaca gatgcaaaaa aagaatgttg ccgaaaactg gagaaaagaa
     9841 acattcgctt ctcatttatt caggtggatt tttatctgtt agcacgatta tcacatggat
     9901 ttggcgaaga aagagagggt aaatgaatga aatggttcaa gcgaatagtg attgcagtac
     9961 cagttatcat cgtagttatt ttagtcactg tatttttgat taatcaaatc acaccaaagc
    10021 cgattagctt gcttgttaga aaacaatttg acacaagtga aaaagaacaa gtatatgccc
    10081 gaccagatga tttccagcaa aaaatcgaac aaatcgatat aaaaaaagaa atatcctatc
    10141 cttcaaagta caaaaataat aatatggata tctacacacc gaaagtggaa aagaaaaaat
    10201 taccgattct tttctggatg catggaggcg catatgtagg aggggataaa aatgattgtc
    10261 gtgattattt ggaatatcta tgttcagaca cgcagcaaat catcgtaaat atagattatg
    10321 aacgatcacc ggaagcaaaa catcctacac cagttatcca attgaacgaa gccattcaag
    10381 cagctaaaaa agagataaaa gatcaagcag attggtcgaa tatttcgatt ggtggaaatt
    10441 cggcaggtgc acaaattagt ggagaatatt tgttagcact tcaaaatgaa gaaattaaaa
    10501 aagctgatca tcttgatccg actttggaga acaagcagat tacgaagttt atttctttgt
    10561 ctggtctgtt ggatccttct gcacttactc aagtaagtga taaaatctct agctttcttt
    10621 atgaaaaatg tggatgggct tactttgata ataaggactt tgaacaatca gagaaggtca
    10681 aaagtttagc cttggtcaga catgcggatc gttggacgca aaacacattc ttaacggatg
    10741 gaaatacaaa tacgtttacg aaacaaatgg aagaagtaac ttctgtattt gagaaagcgg
    10801 gggtgaaagt cacaaaagta gattatgcgg agaaaaatgc tgttttgaac catgaatatc
    10861 agtttgattt cagcaataaa caagcgcaag aaacatatca aaagttagta atgtttttca
    10921 aggagtaaag tcttatgatg caaaagaggt tgtaatctgt cacttagctc caagtcacaa
    10981 ggagcaattt caataaacaa gcttttcatg gtttatgaat attgtaactt gtgactgagg
    11041 agttagagat ggcaaggggc accttttatt cgaaatttgg gaatatcaca cgattattgt
    11101 cacgatctct tttacgtaaa ttttataagt cagatttgtt gttttgatcg tttaaaaaaa
    11161 gcaacaaatc cgaagcctgc ggaggcaaga agggacaaaa agccgagtgg taagcaaaag
    11221 aatgctggtt ccactaatat tccgttgtta ttgatataag gctgggaaca aagatgaata
    11281 gcaaataaaa tcaatgcact agcgaaaaaa agcaaagaaa tatggatagc tttcataagc
    11341 agcacctcct tttttataat tgtatgataa atagattaag aatctataaa tgtgacaagt
    11401 ttgttaggat gtgaataaaa tgatcatcta gcgaacttga aacaaagatg gctaatgata
    11461 agcaattaat gattcagcaa tcagataggt acaaagttta ccatcatacg tctagaccaa
    11521 taatagaaaa tatgggaata taatagaaaa gatttaggat acccccaaaa gaatttcccc
    11581 aaaaattcga tgtatcctaa acttttttat tttacataac aatcatatca actgtgaaat
    11641 aaaattacaa atgataacct aaaatgaggc caaaagccag tgttatcaag gaaatactta
    11701 attcaccaaa atttttttta attttttaga aaataagaaa caaaaataat aaaaaaaaga
    11761 aaagataaat tttttactac tgtatactaa ctttgttatc gcatctaaca agtaactcga
    11821 ataataccaa tacaaccttc tccaaagatg cgatgacata cgttctaacc caccgactat
    11881 tgatgttctg taccaccctt gcagaaccaa aaaagccact accaaatatt tggtagtggc
    11941 tttttttgtt ttatggattt ttcgcttttt ctgttatggt gctattcttt gatttcagaa
    12001 atagtatgtc gaactttagc gatagaacga cgtgattctt tttcgttgta aaacatcaaa
    12061 atcacatata gagagtccaa aatgcttagt tgagaaatac gggaagctaa agcttcagat
    12121 cggaattctg tttcttcaga aatagaaata aaaacgacat cgccaagttt agcaagggaa
    12181 gaattagctt ggctagtaat aacgattgtt tttgctccag tttttcttac ggtttcagca
    12241 atatggattg tttcttttga ttgccctgtg tgagaaatca aaacagcaca gtctttttcc
    12301 gtcaataaag aagcttccat caattgaata tggtaatccg tgctgtgaga agttgcgata
    12361 ggggaacgca aaaatttatg ataagcgtca gttgctacaa tctctgaacc gccaacaccg
    12421 aaaaaataga cacgtttaga ttcattgata atagtagccg ctttttttag atccttttgt
    12481 tgtaacaact tttttgtgtc atttaaagtt gaaatactag actcgaacac cttttgcgcc
    12541 atagtgagct cagtatctgt tttctgaata ttttcgtgga tagaaatagc agatagatca
    12601 ttttcttgga tcaacatggc cattttaaaa tctttaaatc cattataacc aagttttttt
    12661 gtaaattgaa aaaaagtaga gtcagcaatg cccagttcac ttgctaaatt gctaatagga
    12721 ctatgactta ctttgcttgg attttctaaa atataatcgg cgatagcctg ttcttttggg
    12781 ctgaagtcgt tgtacattgt tttgatttgt agtcttatgg agacgctcat gagaattcct
    12841 cattttcata ataagattat cattttttcc gttctcatta atgttaaaga tacaaggaga
    12901 gtaggaaaaa atcaaacaaa aaatattttt gtaaaatcta tttacaaaaa aatttttttg
    12961 tataatgagg gtataagaaa tggaggcgct atcatggaaa ttggtgtaat tggtttggga
    13021 aaaatgggat tgaatttagc tttaaactta aaagagcacc atcacaaagt acaaggactc
    13081 gacatttcaa gtacagctgt tagtcaggca agagaaaatg acattcctgc ttatcaagag
    13141 atctctgaat ttctagctac ttttgagcag aaaaaaatca tctggttaat gcttcctgct
    13201 ggagagataa ccgaaaacat gttaagaaaa ctttttccaa aactcggacc aggagacatt
    13261 attattgaag gcggaaactc ttattataaa gattcaatcc gtcgagcaga agagtttcag
    13321 aaaaatgaaa tcggttactt ggattgtggg acttctggag gaatcgaagg agcacgacat
    13381 caagcctgct taatgattgg aggagataaa gaaacttttc tatccgtgga acaattattc
    13441 aaagatgtag caattgaaag aggatatctg tatgctggtg catccggaag cggacacttc
    13501 ttgaaaatga tccataatgg aatcgaatat ggaatgatgc aagcaatcgg tgaaggattc
    13561 caacttgtac aaaaaagtga gtatgctttt gacttggaac aagtcgcacg tgtttggaat
    13621 catggttcgg tgattcgcgg ctggctgatg gaaatcatgg aagatcagtt aaacgaacat
    13681 cccaatttaa gtaattatcg gggaatcgtt tctgcatcag gtgaagcaaa atggacggtt
    13741 gaaacagcgc tagaaatggc tgttccagtt ccagtaattg caactagttt gttcatgagg
    13801 aatctttcac aggaagaaga tagtttttca gcaaaagtag tttcagcact aagaaatggg
    13861 tttggcggac atgaaatagt tgaaaagggt gagtaaaatg ccagattatc atatagcaat
    13921 cgttaattcc agcagtttcg gaagagtctt tccacaccac ttggaaagat taaagtcagt
    13981 tggagacgtt catttcttta ctgttgatca agagattcca ggaaaagaac tagcggagtt
    14041 acttaaagga ttcaatatca ttattgcaag tgttacgcca ttttttcgac gagatttttt
    14101 tgaaaacaaa gatgaactgc tattgatttc ccgacatggt attggttaca acaatattga
    14161 tttaaaagca gcaaaagaac accagacaat cgtatctatc atacctgctt tagttgaacg
    14221 aaatgctgta gcagaaaata atataactaa tttgttgtcc atgcttcgac gcacgacaca
    14281 agcacaagca agagtcaagg acgatcgatg ggaagatcgg gcggagttcg tcggtaggac
    14341 gctgtttaac aaaacagttg gtgtgattgg tgcaggaaat accggaagcg gagtaatcga
    14401 aattttgcgt aacggttttc gctgtgatgt tctagcttat gatccttaca aatcagattt
    14461 atacatcgaa agctttggtg caaaaaaagt agaacttcaa gaattactgg aacaatcaga
    14521 tatcatttgt ttatgtgcga atttgacaga agagaactat cacatgattt ctgataaaga
    14581 agtcgatcag atgaaagaaa atgtttatct atctaatagt gcaagaggcg ctctagttga
    14641 tgaagaagcg atgattaatg gtctgaaaag cggaaagatc gcaggatatg ccacagatgt
    14701 tttagaagaa gaaccgggac gtcaagatca tccgtattta gcgtttgaac aagtagtgat
    14761 tacgccacat atatcggcct acacaaggga atgtttagaa gcaatgggtg aaaaatgtgt
    14821 cagagatgtc gaacagatca gtcagcacct tcttcctgaa cgttctgtcc agacaaagag
    14881 caactatata aaaggatgat gaagaaaatg gtgaacggtt taaaagtgaa aacaggccct
    14941 caattttatt tatatgaaga aggtggtatt tcaaaagttt ctgatctctt gaaatcatac
    15001 ggcgcgaaaa gagtactggt cacccacgga acggtatcat gggaaaaggc gctacctaaa
    15061 ttagtatttt tgaatgacga aacgattcaa tttttttatc atcgttattc tggagaatgt
    15121 agttatgctg aagccagacg aatagctaca atcatcaaaa aaatgaaatc gatttcgtag
    15181 ttggcgttgg cggaggaaaa ctgaccgatc tagtgggtta tagtgccaat cttgcaagaa
    15241 tcgatttcgg agtcatccct actttagcta gtaattgtgc tccatggaca cctcttgctg
    15301 tcatgtataa ggagaatgga caagcagaag ggaaaacaga acacttttac agacaagctg
    15361 ctttttttat aacagatccc caattagtga ttgattcccc tgttccatat ttcattgccg
    15421 ggttagcaga tacactagca aaatggtatg aatctgagct catcttagaa caagattttt
    15481 tgcaagatga atcatttttg aagctagcac aagatactgc gaagatctgc aaagaagaga
    15541 ttttgaatca ttctgctaaa gcaatccaag atatggcaca aagaaaactg acatcggagt
    15601 tcaaacagct ttcagagatt atctttgctg ttgctggttt agttggagga ttaggagata
    15661 aatacgcaag aaatgcggca gcacatgcta tgcatgacgc tatcagtaaa tatattccgg
    15721 aaagccatcg ttttctacat ggagaaaaag tagcgtatgg gattttctat caactggcac
    15781 tagaaggtcg ctgggaaaaa atagacgagt tatatccttt gtatcgggaa ttagaactgc
    15841 cggtttctct agaacaaatg ggattatttc cgaaagataa acagataata gataaaatgg
    15901 ctgaatttat tgattcgaaa gagaaagtgc atttgattcc tatagaggta acacagaaat
    15961 cactgataca gtcaatgatg gaactggaag gttatatcag aaagatctga aggaggagga
    16021 cacatggaaa cattaagtgt agtacaaagt ttgttgattg ctttatgggt agccgcggtt
    16081 atgtcccgct ggttaggtgg aggagccacg ttgaccttac gtttttctcc tttgatgact
    16141 ggattagtcg tcgggttgat catgggggaa gttgcacaag cgatgattgt tacagccgct
    16201 ttgcaaatga tttatatggg ggttttttct ccaggaggat caatgccagc tgaaccatct
    16261 attgcagcag ctatcgcagt accagtcgca ttattagggg atctgtcgcc agaagcagcg
    16321 attgccgttg cggtgccagt cggattgctc ggaagttact tgtatcagtt tcgttttttc
    16381 atcaatactt ttttaggtaa atatacagac aaagctgtag aagatttgaa tacaaaagct
    16441 atggcccgat caattattct ttatccaacg gttgcctcat ttttattatt cgttccgctt
    16501 gttttcattg ctttatattt aggggcgcca ttgatcgctg atgtaatcaa agctttagag
    16561 ggaacagtcg ttatccacat tcttgaagta gtaggtggag ggttagcggc aatcggtatc
    16621 gcgacaactg tatacgttat cggtcgaaaa gattatctgg tctttttctt ccttgcttat
    16681 tttatgagtg ttgttttgaa atctttagat attacgatgg ttacttatgc catttttggg
    16741 attattatcg ctttgatctt tgtccagtcg caaaaaggga aacaagtaca gcctgccaca
    16801 agcaataaca attcagcatc ttttgatgac gaagatgact atgatgacgg attttaattt
    16861 aggaggaatg ggaaatggct gaaataatgg ataatcaaac aggtgctcct gaagaaatca
    16921 cgaaaaaaga tgtaacaaaa gcctatctga gatggcattt tgcaaacgaa attcctcact
    16981 cttttgaacg ttacttggcg ccatcactac tatacggaat gatgccaatc ttgaaaaaac
    17041 tttataaaga tgaagactct ttaaaagcag catataaacg gcagttactg ttcttcaaca
    17101 ctcaattaag ctggggtggc ggtgtgatta ctggcctaat gtcttctatg gaacagcaaa
    17161 gagcagaaga agagtatgaa gaaaaagaga tcttgatgca ggatgacttg atgtataaca
    17221 cgaaagcggg attgatgggg gcactagcag gaatcggaga tgcaatcgat tcaggaaccg
    17281 tccaatatat ttttatcgca atcgcggtac cttgggcaca acagggaagt cctttaggcg
    17341 cactttttcc ttttatctgc tttgggttgt atcaggtttt actaggggta tttttcgcaa
    17401 gacaagcttt cactatgggc cgtaatgcta caggcctaat gcaaaacact ggtgttcaga
    17461 cagcgattga aatgctatca gttttagggt tgtttatgat gggggtgctt gcgggaaact
    17521 atgtaaaagt agaatcttca ttgaaatttg cgatatccgg acgtgagttt gttatccagg
    17581 aaattcttga tcaaatcgtg ccagggatat tacctttagc tgtcgtaatg ggtgtgtact
    17641 tgttctatac gaaaaaagga ttgaaagtca cacaagcatt attatggctg actggaatat
    17701 taattgtgct agcaggaatc ggtattttat aaaaagaagg gaacgtgaat aagatgggtg
    17761 tagtcaattt agcgcgtgtg gatgagcgtt tgatccatgg gcaagtaatg gtaacgttat
    17821 ctcaaaaaag tggagtgaat tccatttttg ttgtagacga agttgtagca aaagataaat
    17881 ttatgagaga tctttacaaa aatgcaggaa gccgtacagg acaaaaaaca attgtcatta
    17941 caccagagaa agctaaattc tattgggatg aatatcaatt taaagaatac aattgtattt
    18001 tgatcgcaaa aacagtccaa acgatttacg acttagtaaa acacggaatc cccatggaag
    18061 aattgaatat tggagggatt gctcaaaaaa atcctgatac agatctttta gtgacgaaat
    18121 ctgtttattt aaataaatca gatgctgaaa aattgaaaga aatgaatgaa caatatggcg
    18181 taaagaatat ttattttcaa gccactccat ctgcacctaa aacaggatta aaagatgtat
    18241 tgaacaagtt tgatttgtca taaacaaatg cttagaaaaa agataaagag ggcgaaaaaa
    18301 tgaagaagaa cgagctgttt cgtgattggg aatttcgtta tcgctatatt taccgtaagc
    18361 gccgtacaaa aaagagtaaa cagcgttttc tttcagcatt agtatcagat atttacagta
    18421 tgagaacaga tgtgacagtc attgcttacg atacgctagc ctaccgatca aaaaatattt
    18481 atgttggaga tatcgaaaaa gcagagaaag ttatctgtac ttattacgat acacccgttc
    18541 atgcattagg aagttatttc atgtttgatt ggaaagacca aaggaaaaaa acaatctact
    18601 ctatattatt gtccttcatt ttgttgttca gtttaggttg gtggggaatg atgatatata
    18661 acaaaaatcc tcatcacgta ttcgatctgc tatccgtata aacaggtatc actgtactag
    18721 catttgggag ctactttttc ttattgggaa aagcagctcg cggatggcct agcagacaaa
    18781 cttttattcg aaatacttca tccatattaa cgatgctaga aatgatccgt acgattgatg
    18841 atccgagtgt agcgtatgcg tttgttgatg aaggctgtta tggagaaaag ggcttagaca
    18901 gcgtgagatc gggtatgaaa aaagaggcta ttctttttta tctagactct gttggggcag
    18961 atacaccgct acagttttcg ggaaattatt tttcaaataa agaacagtgg ctgaaacaag
    19021 ttgataagtt gaaagaaaaa aacgtcaatt atatttttag tgcaagaaaa aagcaagcgc
    19081 agttcttcta tttgaccaaa acagatttac gagggaaaac atttaattgg caaaatgcca
    19141 atcagattat tgctcttttt cgataagtaa aaagtgcaaa acaaggagtg agaagactaa
    19201 tgttggaaat catgatcgtt acacatggta agttgagcga aggactgaaa gatgcggcgg
    19261 aagtaattgt cgggacatcg agccatattg aaacaatgtg cttagagtct ggggaggaca
    19321 tccaaacatt cggagagaag gtcaaagaaa aattaactat gatcaacaca gcagaaccca
    19381 tgctagtatt tgttgatcta attagcgcaa gtccgtacaa tcaagcgctc ttggcagtca
    19441 atgaactgac tgaagaaaag aaagcagcca cttatgtcat agggggcgtg aatctgccaa
    19501 tgttgttaga agcaatcaat catcagatgc ttcacacacc gatagaagaa gcggtggaac
    19561 aaattgtcaa acaaggaaaa gataatttaa ctgtttggca tgcttcagcg gaagaaaaaa
    19621 aattagatga ggacgatttt tagaaggaag gctgaaaaga tgaagtgggg atttagatgg
    19681 tatggtgaaa aaggggattc gatcccatta aaatatgttc gccaaatacc gggaataaat
    19741 gggataattg gaactttgct gactaaaatg cctggagatg tttgggagat ttcagaaatt
    19801 gaggagttga aagcatctgt tgagagccaa ggactggaac tgcttggaat tgaaagtgta
    19861 gcgatccacg atgcaatcaa ggcagggaca gatgaacgag attactatat tgataactat
    19921 atacgaacaa tcaaaaactt gtctcgatgt ggggttcgat tgatttgtta tagcttcaaa
    19981 ccaatttttg gatgggcgaa aactgatttg tttaatgaaa acaacgatgg aagctattct
    20041 cttttatacg atcagaaaat cgtcgatcag atggagccag gagaaatgta tcaattgata
    20101 cacagccagt caaagggatt caaattgccg ggttgggaag aagaacggtt gaaaaaattc
    20161 gctcagctgg aaaaactgta tgaaggaatg accgaagaag aattatttga aaatctgact
    20221 tattttttag aaaaagtgat tccagtgtgc gaaaaagcag atgtaaaaat ggctatccat
    20281 ccagatgatc cgccatggga actttttggt tttcctagag tgacgaaaaa tcttggcgac
    20341 ttgaagaaaa ttctaaatgc agtagattct ccatataatg gactaacgct gtgcacagga
    20401 tctttagggg caaatccgga aaacgattta gttgaaatca tccatgaggt aggttcgcgc
    20461 atccattttg tccacttcag aaacgtggag tttttaggag aaagaaagtt caaagaaacg
    20521 gcacatccct ctacagaagg ctcccttgat atgtatcata ttatgaaagc gttggtgcaa
    20581 gaagggttcg acggtcctat acgccctgat catggtagaa ccgtgtgggg tgaagtggct
    20641 atgcctggat atggcctgta tgatcgtgca atgggactca cttacatgca aggtctatat
    20701 gaggcgataa gtaaggaaaa accactggga gagcattatg aataaaatca agctcttcat
    20761 ctttgatatg gatggccttt tattagaaac tggacgttta gcttatcgtg cttatgtaaa
    20821 atcagcacaa aagtatgatt atgaaatgcg taaggaagtc tattatttac taactggcca
    20881 aacagaaatg gcgataagag aacaaatggg cattttgtac ggagaagatg ttccatatat
    20941 caaatggcga gaagcaatca atcaatataa agaaaaaatc gtgaaagaag ataagagagt
    21001 atatacgaaa aaaggagcag aagaaatttt atcttttgca aaagaaagag gaatccatac
    21061 aatcgtggct tcgtctaata cacgggtaaa agtagaaatg tatttaaaaa tggaaaatct
    21121 atatgccttg tttgatcaaa tcatttcagg ggatgatgta aaaaaaggaa agccggaacc
    21181 agagatcttt ttgaaagctt gttcaaaaat gaatattcct ccaagtgaag cacttgtatt
    21241 tgaagactcg attgcaggga tcgaagcagc aaggcgagcg ggcattttgt cttttctcat
    21301 caaagatcat ttgatagggt tgcccgatca taatgggaag cataagttga aagtagatgt
    21361 aagtttatat gaatccaata aagcagacta tgaattttat gacctgcatc aagcaaaacg
    21421 atttttagaa agtaaagggt tgtatctcta ataaagagga ctattttcta gtcctcttta
    21481 tttattgtcc tgcacgactg agggaacaga tgaaaaagaa gtaatttttt attttgaagt
    21541 atctacctta tttgtagtga acaatttaga acaaacacaa aacgcatcta ctgttatcta
    21601 ccagtagatg cgtttaaaga gaagaacgag aatcgtccat atgagggttt ccactcctta
    21661 tgcagatttt tttaattctt gcactgcttg ttcgatcgta acacctgtcg ctacatgatt
    21721 ggtattttct ttgtcaaaaa cgacaaatag attcaaatct gtatccaagg ttactcgata
    21781 ttgtatatct ttgttataga atgtcatagc cattctcctt tctttaaata cttgctgaaa
    21841 ggcaacgaac gcgttgataa cgaaattcca tttataagta taccaccaat tgaaaggttt
    21901 tcatagttaa gaaattttaa agtcaaaagt tgcagataaa agcaaataaa caagaaaaca
    21961 aaaagtgaat caatcgcggt tattcaactt tttcttcgat tcgaagacaa tagaagacaa
    22021 tgaattttat atttcattgc attatccttg tgttattaga aaaagcatga tatattaaat
    22081 gagtaatcta ttttgaaacg taatttgagc gatatatcta catagataaa actccttttg
    22141 cctatcaaat atttattgca acgaaaaaac gtacattgat acgtatcagg aggaatttat
    22201 ttatgaataa cggtacagta aaatggttca acgcagacaa aggttttggc tttatcactg
    22261 gtgaagatgg aaatgatgta tttgcacatt tttcagctat ccaaggtgac ggcttcaaaa
    22321 ctttagaaga aggccaagca gtgtcttacg atgttgaaga tggtcaacgt ggccctcaag
    22381 caacaaacat tgttaaagct taataaaaat tgacttttaa ccgtcttttc gaaagaaaag
    22441 acggtttttt tgtacgaaaa aat
//
LOCUS       DAYNVV010000043        22060 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.043, whole genome shotgun sequence.
ACCESSION   DAYNVV010000043 DAYNVV010000000
VERSION     DAYNVV010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22060
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.043"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(57..104)
                     /locus_tag="ACGXWR_001889"
                     /pseudo
     CDS             complement(57..104)
                     /locus_tag="ACGXWR_001889"
                     /inference="COORDINATES: protein motif:HMM:NF011335.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(418..1332)
                     /locus_tag="ACGXWR_001890"
     CDS             complement(418..1332)
                     /locus_tag="ACGXWR_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFK0803444.1"
                     /translation="MMKFGKNQNTEKQTPKEKKPRVYKVNPRKKVVIVLWVLLGLSFS
                     FAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWELNDKSIDNRIEN
                     LKAYLTEELQALNVDTVRKDIPVSSSVKGFQIWTVEADGDNQFDVTYSVDQLITEGEN
                     TKTVHSAYIVSVYVDSTGNMVLIKNPTITSIPKKSDYKPKAIESEGTVDSITTNEINE
                     FLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIYNRKDNQVTVSLTVEY
                     IDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            complement(1347..2348)
                     /locus_tag="ACGXWR_001891"
     CDS             complement(1347..2348)
                     /locus_tag="ACGXWR_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HFK0803445.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDGGFSNIHYGGV
                     DVSAEVLAHKPMVEKVAKEYGIEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLGVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGDEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKFEGWKYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTRHIPLLEAKA
                     GDLVFFHSTYNAGSYITHIGIYLGDNRMFHAGDPIGYADLTSSYWQQHLVGAGRIKQ"
     gene            complement(2345..4528)
                     /locus_tag="ACGXWR_001892"
     CDS             complement(2345..4528)
                     /locus_tag="ACGXWR_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFK0803446.1"
                     /translation="MKPSILNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVTPSGLSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHALMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNMTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRM
                     MRKPRMLMHAHMHRLQRKLGRSVTALGAGSAIASATGKKGQSGSGSSASTQADHSRPN
                     GQEKSTLGKRIGQTIGTVADTKDRMVDTAGNLKEQVKDLPTNARYAVYQGKSKVTDNV
                     HDLTRSISQTKADKASGRKKQQEQRRKTIAERRSEMEQVKQKKQPASSVHERPATKQE
                     QSHDGQTSRQTTVQASYRESQQAKQERPTVKSDSSSLKTERQSNTVQERTVQKPVTST
                     APTDRASQRSITKERQSTVQRVPLQNTKSRPPIKTATIKKGSKKP"
     gene            complement(4531..6978)
                     /locus_tag="ACGXWR_001893"
     CDS             complement(4531..6978)
                     /locus_tag="ACGXWR_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFK0803447.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSILSAQERSKNEVTGKLKTVAYDKIDQQTDALISM
                     IGENQVDYRFFIGFKLLLNDQEFSMKSLTVEAKNAFTDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYPLSKKKLEH
                     ETLIKTYDLIKPTRCLVEEKQRYLKIQQEDETAYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVNLTSDEKNKGLLDPYVIMKNTKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSDGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            complement(6962..7354)
                     /locus_tag="ACGXWR_001894"
     CDS             complement(6962..7354)
                     /locus_tag="ACGXWR_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFK0803448.1"
                     /translation="MKKIRSYTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAV
                     MILGNLPPLSMIEGAFLKYFGIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRRKLTY
                     AGKKVTLGRNQPQEAITAVRSEFYGISN"
     gene            complement(7441..7938)
                     /locus_tag="ACGXWR_001895"
     CDS             complement(7441..7938)
                     /locus_tag="ACGXWR_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFK0803449.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSISELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMSDVARYYIEETGALGEVPASLQNYIDYESYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            complement(8055..8279)
                     /locus_tag="ACGXWR_001896"
     CDS             complement(8055..8279)
                     /locus_tag="ACGXWR_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803450.1"
                     /translation="MSGTYLSIYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFL
                     IIAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            complement(8383..10293)
                     /gene="ltrA"
                     /locus_tag="ACGXWR_001897"
     CDS             complement(8383..10293)
                     /gene="ltrA"
                     /locus_tag="ACGXWR_001897"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFK0803451.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(11077..12282)
                     /gene="mobT"
                     /locus_tag="ACGXWR_001898"
     CDS             complement(11077..12282)
                     /gene="mobT"
                     /locus_tag="ACGXWR_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HFK0803452.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            complement(12305..12458)
                     /locus_tag="ACGXWR_001899"
                     /pseudo
     CDS             complement(12305..12458)
                     /locus_tag="ACGXWR_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(12461..13846)
                     /locus_tag="ACGXWR_001900"
     CDS             complement(12461..13846)
                     /locus_tag="ACGXWR_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFK0803453.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            complement(13875..14261)
                     /locus_tag="ACGXWR_001901"
     CDS             complement(13875..14261)
                     /locus_tag="ACGXWR_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFK0803454.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            complement(14277..14591)
                     /locus_tag="ACGXWR_001902"
     CDS             complement(14277..14591)
                     /locus_tag="ACGXWR_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFK0803455.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            complement(14944..15423)
                     /gene="rlmH"
                     /locus_tag="ACGXWR_001903"
     CDS             complement(14944..15423)
                     /gene="rlmH"
                     /locus_tag="ACGXWR_001903"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HFK0803456.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYGLAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            15851..17140
                     /locus_tag="ACGXWR_001904"
     CDS             15851..17140
                     /locus_tag="ACGXWR_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HFK0803457.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVMMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(17179..17784)
                     /gene="ytpR"
                     /locus_tag="ACGXWR_001905"
     CDS             complement(17179..17784)
                     /gene="ytpR"
                     /locus_tag="ACGXWR_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HFK0803458.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVASYGMICSARELHLPNAPEKKGILVLPEDAVVGEVFPK"
     gene            complement(17980..18444)
                     /locus_tag="ACGXWR_001906"
     CDS             complement(17980..18444)
                     /locus_tag="ACGXWR_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFK0803459.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKALEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKQMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYAIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(18466..18786)
                     /locus_tag="ACGXWR_001907"
     CDS             complement(18466..18786)
                     /locus_tag="ACGXWR_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFK0803460.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VIKG"
     gene            complement(18929..20008)
                     /gene="pepA"
                     /locus_tag="ACGXWR_001908"
     CDS             complement(18929..20008)
                     /gene="pepA"
                     /locus_tag="ACGXWR_001908"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HFK0803461.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            20208..20558
                     /locus_tag="ACGXWR_001909"
     CDS             20208..20558
                     /locus_tag="ACGXWR_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFK0803462.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKTSFLKEGAIEGAWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLDISRKKGAID"
     gene            20743..21696
                     /locus_tag="ACGXWR_001910"
     CDS             20743..21696
                     /locus_tag="ACGXWR_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFK0803463.1"
                     /translation="MESREKIAVLIPCYNEEATISTVIEDFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAAHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVKNTITYLYKTKIRDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMCKDYKPLLFFGIWTIFFFLFGLVMGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYQNKEMK"
     gene            21709..>22060
                     /locus_tag="ACGXWR_001911"
     CDS             21709..>22060
                     /locus_tag="ACGXWR_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803464.1"
                     /translation="MHKKKENLFPTFFATLFASGFAFFTSYGLGTLNPTVIIGLAMVL
                     LLAFKQYGIELFSIKNKVAAIARLFFSAAFALTLSIGRQIQFQYVSANYTKTTIADGS
                     IFYFLVYFSIFVYSF"
BASE COUNT         6221 a         4527 c         4052 g         7260 t
ORIGIN      
        1 gcatcaacat gagctaaaac tccaatatta ataattttca tgtgattttc ctccattcaa
       61 aagcccaaaa gggcataaaa atcccagtga taaatactct tatcactggg atttttatgc
      121 ataaccatag gcatacaaag catacagata ttctccggat actttagaat cacatgataa
      181 aggtattctt aaactgggtg caaaaaacta agccctccta aaaaaggaca tccaattatt
      241 tgttcccact atcaaattga cagtttattt aagaatacct tgccgcatat ttattaactc
      301 cttttaaata gatacttaaa taatagcacg taagagcata tttgtaaagg aatctccaat
      361 tttttatcaa agagagtacg tgattacaaa atagctgtaa taatgtacca atatttgtta
      421 ttctataatc ttccaattac tcccgttctt ttcaagtacc aaatcaaatt gagatacctg
      481 cgttgctttg gtctgctggt cgatatactc cactgtcagc gataccgtga cttgattatc
      541 cttacgattg taaataggat ttaccagttc ttgaaagatg tactcttttc cgattggttt
      601 taatatcccg tcattcacat agtaggaaag ttcactggct gtcgctgtag gatagagctt
      661 gaagaacgtc gttaaaaact cattgatttc attggttgta atggaatcaa ccgtaccctc
      721 actttcaata gcttttggtt tatagtctga tttctttggt atgctagtaa tggtcggatt
      781 cttaatgagg accatatttc cagtactgtc tacatagaca ctcactatat aagcagagtg
      841 gacggtcttt gtattttccc cctctgtaat gagttggtct acactgtagg ttacatcaaa
      901 ttgattgtcg ccatctgctt ctaccgtcca tatctgaaat ccttttacag aagacgatac
      961 aggaatatct ttacgaactg tatcgacatt cagagcttga agttcctctg tcagatatgc
     1021 tttcaggttt tctatgcgat tatcaatgga cttgtcgttt agttcccatg aatagtagac
     1081 tttcgcaaag ttctctacaa aattttccac atgatgagta tcgacatatt ccttttctat
     1141 gatggtggtt tcatgaatgg tatgggtatc aatggctgta aagtgcttga atatcgcaaa
     1201 gctgaaacta agtcctaaaa gtacccatag gacaatcaca acctttttac gaggattgac
     1261 cttatagaca cgaggtttct tttcctttgg tgtctgtttt tctgtattct gattttttcc
     1321 gaatttcatc attgaatcgt cctttcttat tgtttgattc gtcctgctcc cactaaatgc
     1381 tgttgccagt aagagcttgt taagtcggca taaccgatag ggtcgcctgc atgaaacata
     1441 cggttatcgc ctaaataaat cccgatatga gtaatataag agccagcgtt ataggtagaa
     1501 tgaaagaaaa ccaaatcgcc ggcttttgct tccaataatg ggatatgccg ggttacatca
     1561 tattgctgtt gtgctgttcg tggtaagttg attccagctt ttccatacgt ccattgtgtc
     1621 agtccgctac aatcaaaaga ggtagtcggg gaagctccgc catagacata cttccagcct
     1681 tcaaatttca gagcttcgtc catgatggct tgtactgtat catcatcaaa ctctgttgtg
     1741 acaagatact gcgttaccag ttgcacataa aacatattcc cgtaattgta tcgccagccc
     1801 ccattgatag gtatggctat gggattgggg taagacactt tttcgtcacc cgaatactct
     1861 tttgagaaac tttgagccag ttcaaaggta tatttattcc cacgattagc cacatatcct
     1921 aagaaaccac caccataatt gtaggactgg ataaccgatt ctaaatctac accaagcctt
     1981 tcgctactgg ctaataactc actgaaatac ttcacacctt gcttaatgga ttcttctgta
     2041 ctcaatgaat taggtggaag accgagggat tccgaggact gcataacatc ttctgctgta
     2101 ccacccgatt ccacctgtat aatcgcaaga agtatattga cgtattcttc aattccatat
     2161 tctttggcaa ctttttctac cataggctta tgagccagca cttctgcgga aacatccaca
     2221 ccgccatagt gaatgttgga aaaaccgcca tcttgttcat ctgaaaataa aatggcgaca
     2281 aacagaagca gtgagaagac catcaagaat aatcccgaac caccaatcac taaagttttc
     2341 agcttcatgg tttcttactg cctttcttaa tggtggcggt tttgattggt ggtctacttt
     2401 ttgtattttg tagtggtact ctttgaacag tagactgacg ttcttttgtg attgaacgtt
     2461 gtgaagctct atctgttggt gcagttgaag ttactggctt ttgaaccgtt ctttcttgaa
     2521 ctgtattact ttgacgttcc gtttttaaac ttgaagaatc ggacttaact gttggacgct
     2581 cttgtttggc ttgttgagat tccctatagg aagcctgtac agttgtttgc cttgaagtct
     2641 gtccatcatg agattgttct tgcttagtgg ctggtctttc atgaacggaa gaagctggct
     2701 gttttttctg tttgacctgt tccatttcag agcgacgctc cgcaatggtt ttccgtcttt
     2761 gttcctgctg tttcttgcgt ccactggctt tatccgcttt ggtttgagaa atacttctgg
     2821 ttaaatcatg gacattatcc gtcactttag attttccttg atatactgca tatcttgcat
     2881 tggtcggcaa atccttaacc tgttctttca aattaccagc agtatctacc attctgtctt
     2941 tggtatcagc tactgtaccg atggtttgac cgatacgctt tcctagtgtt gatttttcct
     3001 gcccgtttgg tcgagagtga tctgcttgtg tactcgcaga acttcccgaa cccgactgtc
     3061 cttttttacc cgtagcactg gcaatggcag acccagcccc taaagcagtc acggagcgtc
     3121 caagtttccg ctgtagacgg tgcatgtgag cgtgcataag catacgaggt tttctcatca
     3181 tacgacttcc cacactttga gaatcgttac tctgtagaga aaacatactc attaaatcgc
     3241 ccagcttaaa gtagattcct gcaaaggtca caatctgtag aaaagcaatc aaaaagaacg
     3301 gataaccagc cgataaggta tagagcatgg ttgaaatact aaatgctgtc gtaataatca
     3361 atgtgattcc agctcgtgtc aaaatggtat taaagagctt tgttatggct cgttttgaca
     3421 taccatcaaa tgatggaatc atgcttaaaa taaagctcac aggcagaaac atagcataga
     3481 tgataaaaag tacctgcgag aaaatcatga ttcctgttaa taggaataca aatatggaaa
     3541 tcccaatatt gaagacaaat aggaagaaga ctgtacctaa acggttaatc gtctttgtaa
     3601 tcgtcatatt ggtattgctt ctatcttcaa tttcttccgc aacaattttt tctctgtctt
     3661 ccccattgtt ggaatctgga ctggttgaga gcaggctttc cacacggtca ataccaatac
     3721 tttcaatgtc tgaactgtta tattgaagca gtagccacgg ttgctgaacc tgtatggaaa
     3781 ataggctgtc acgtatcaag tccacactgt ccttgccttg actatctgaa tggggcatga
     3841 caatttttgt acccagtgac aaactagcgt tgctgatgtc tgatgaaaag tcattgattt
     3901 ttttaatgta gtcgggagcg taggcaataa aggaagccga taggataaaa accagcacaa
     3961 aattcatgag ggcatgaatt gcctttgtgg tttctctctt tatcagtcct gtataggcaa
     4021 cataaacccc aagaaccaaa atcaagagta aaaggaatcc aacatagaaa ccctctgttg
     4081 atagtccact aggcgtaacc cctgcaaggg tctgcatatt cttgccaatg gaatctgctg
     4141 tagcggaaat gaagtctaag gaataggctt cctgtactaa gtaacccgtc gcattggaaa
     4201 cataaagact gattgtccaa ataaaattgg taatggcata tagtccatac atgacttgtt
     4261 ttccaattcc gtccgaccag ttccacggta gccagcccca gctattatcc acataaaaat
     4321 ccagttgata gttttcaagt gggtatcggc tgtattcatt tgccacattg accgtatcat
     4381 ctaccaagcc cgcagcttga accaccgttc ccagcatggc taaaagaaaa atggcaatca
     4441 caagtgtgaa agccactgtc attgccactt tacctagacg tttcagcgtc cagtttgatt
     4501 ttattctgtt taatattgat ggtttcacat ttacacctct tttcgcacag gtggtctggt
     4561 atcaaaggca tggagcagtt cttcaaatac agggtggaac tgtatcacac cgacacgacc
     4621 atataaatca ctgataaggc attgcccgtt ttccaaatca cgcaatcgct tctgattgtt
     4681 ttcgtcctct gggtctacac caaaaaaggc aagggttttt ttaatctcgt taaggtcagt
     4741 ggaacgaaag gcaaatttta agccgaggtt atttttcagt ttttcatcta agaggtcatc
     4801 tgtattttgg gtcacgaaat ataccccagc gttcatagca cgaccagcac gaaccagctt
     4861 catagatagt gttttccctt gtgccacctg taagaagctc catgcttcgt ctaagtctac
     4921 aatcttgaaa atacttcggt ctgtatggat aaagtccaac gcaaaggtac taatgacaat
     4981 cagcattgct accgatagta actccattgt ggtatattcc tcaaaggaag tttccttgtc
     5041 aggaagtacc aagtcggcaa cctgtataat gttcagttgt ttttcaaggc tgatagactg
     5101 ctctacataa ccatcactaa aaagcagatg ggcaaagtca tagtctgtaa aactttcgat
     5161 atggtcggct atgctggtac ttagtggcgt attctcaacc cgtaattctt caatcacttt
     5221 catcaaccct cgcacttcac tattggttac tgcacgaatg gcttttctaa ggattgggaa
     5281 gcgttcccca tcacgagagg aaatccccgt aaggaatgtc aaaatatcaa tagccagtga
     5341 ttcagaatct ttggtatttt tcataattac ataagggtca agtaagcctt tgtttttctc
     5401 atcagaagtc agattgacga tattgatttc atgggaaatc tctggcaagg tttctttcca
     5461 tctgccacgt tctgcttttg ggtctacaat cactgcttgt gccccataaa gcactgcata
     5521 atagacgata aggttattcg caaaggattt accaccaccc agcgaaccga caaaggcaga
     5581 cgctaacgca ttggttactg aacccttaac cccttgactg gcaagagcag gtttcagata
     5641 gacattgcgt ccagtatcta agctgtagcc aacataaatc ccctcatttt cacccagcat
     5701 ttgagtagca ccaaaaccta aaccagcgag gaaatcagag gtcacgtatt gaatatagtc
     5761 attcatatat cttttgctgg caggtaaaaa ttcttcatgt aagcccagca tatccccaaa
     5821 aggtcgtacc agtttcacgc tcaaatcatc atagaaatct ttcacttcat tacaacgacg
     5881 tttaagttcg tcaaggtcat ttgctgatac ccttacaaca taggacagct tatacataga
     5941 ttccttgctt tggtctaaat tggtttccag ctcgttcaca ctttccagag cttccgccac
     6001 attagagctg gtttcattat cactttgcca agcgtggtta tccaagtctt tcagttcttt
     6061 ctttttattg cggacagtag atagggcttt acgattcgct acaatttcca cattcattga
     6121 cgtatcaatc ggaaaggtaa attgctgttg ctggtagtag aagatttcag aggacgggaa
     6181 gtccagttcg ccgacaatac tgttgatggt aaagtaagct acataggcgg tttcgtcttc
     6241 ctgctggatt ttcaaatatc gctgtttttc ttccaccaga cagcgagtag gcttaatgag
     6301 gtcataggtt ttaatcagtg tttcatgttc cagctttttc tttgatagag gatactcata
     6361 ctcttcatag gcagtgcctg tctgtccgta aaggtgttca atcagatagc cgaagtcatc
     6421 cttatctaat cttcggattt tgaaacgacg ggagatttta ttttctaaaa gcttttccat
     6481 cttctgaaaa cgcaggattt catcattact catactaaca aaatcgccca tcagcttatg
     6541 gttcacatca tagacaaaat cagtaaaagc attttttgct tcaacggtaa gacttttcat
     6601 agaaaactcc tgatcgttga gaagcaactt aaaaccgata aagaaacggt agtccacttg
     6661 attttcgcca atcatggata ttaaagcgtc tgtctgttgg tcgattttgt cataggcaac
     6721 cgttttgagc tttccagtga cttcattttt ggaacgttct tgtgcagaaa gtatgctgga
     6781 ttctgtactg atttgtaaag catgaatctt gccatcacga ttttgtgcga taagctgtct
     6841 gaaagaatca tgtacttgta ttttctgttc cggacttaga aatgagtaat tgtagggaac
     6901 aagctcatag taagcgtaac attccccatc tttattccag accagattgt tttcaatata
     6961 tttaattgga tatgccataa aattcactcc taactgctgt aatggcttct tgtggctggt
     7021 ttctgccaag cgttactttt tttcctgcat aggtcagctt tcgtcgcagt gcataagcaa
     7081 tgacagactt caaaaatcca taaggctttt taccatcaaa ggtttttgta gacataaacc
     7141 atgtgaaagc cacaggaatc ccaaagtatt tgagaaatgc tccctctatc atagaaagag
     7201 ggggcaagtt gccaagtatc ataactgcaa agagtgacac gacaaaccat gtcatttgcg
     7261 taaaggttat gggaaacgga agtctaaagt cattgatgga gtacaacact ttctcaacag
     7321 accagatact ggtatagctt cgtattttct tcatgtaatc aatcctttca taaaaatggg
     7381 gatagtcttt tgactacccc gtaaacaaga aaatctgcca gtaagaatgt accgacagat
     7441 ttaatagacg atttcaaaaa tcccgtgatt ggttgagata aacgttcccg aaaggtctaa
     7501 atcccgacca taggattcat aatcaatata gttttgaaga ctggctggca cttcgcctaa
     7561 agcacccgtt tcttcaatgt agtagcgtgc cacgtcagac atatcatcac aatcggaatg
     7621 aatgataata tcttcttgat gttcgcttag ttcttcaata cttgaaaaat gagtgagcag
     7681 agcagatagc tccgattgta gttcttctgg caactccgat accatttccc ataggcgatt
     7741 gagttcgcta atagaagtgt attcgtcaac cgtaaagggt aactcgtaat catgaatggc
     7801 gtattcctca tattcatcat tcaagccgat tttctctttg acttcctcaa agtcaatggg
     7861 aaaggtaaac cacgcaccga ccaattcgcc ctcattgtat ttgcctaaat tcgcaatata
     7921 gacttgcata tcgtccatat attcacgtcc tttctttgta gagattcaaa aatccctacc
     7981 gcacttcgtt tggtgtacca ttcctttgcg gaacataaga aaaccactta tattccacaa
     8041 aagaacggtt ttatttaagc accaataatg cgattgaata gctctagtaa aatgtctttt
     8101 actccagcag cgttgaagac taagccaacc gcaataatcg caataattaa aaagccaatc
     8161 agtttgctaa actcacgctt gaagccaaga tacaagccaa tcacaacgat tgctaaaagc
     8221 accagtgatt gagcgtttga tagaaaccag ttatatatgg ataggtaagt tcctgatatt
     8281 ataaatatct caaacttttc cccccattca cacggagcgt gcgactttca ccgcactccg
     8341 cgttccatcg tgtttatatt gaaaagtatt tatgtagtag acctatatca agtttaattc
     8401 ttgattgcca gctaatactc tatatttatt tagtcttatg agctggactt tatttagctt
     8461 caatagagct atatattttt gtattgtttc ttctgtttta gcgtgtatta gacggtgtac
     8521 cgcctctttt accaaaataa gatttttata atcgtcattt ccaccagctc cagttggtac
     8581 aatatgatga caatgtattt cattagcttg ttgaaattct tccagagtta tagcacattt
     8641 tccatgttga gcagaaaata gcgaaattcg attgtctgcg tattctattg tgcgattttc
     8701 caaagataat ttcattaact ggtacatcag taatttatca acacttagat tggtgtggat
     8761 aaattttctt ccctctagag tgtagcaatt cgctaaatac acctttgcca ttggttttct
     8821 gtgttggata tatccaacag ggaaaatagg ttcgccctcg ccagcaacat accgaagcat
     8881 tttagattta ccatatcttg ttgcctcctt tgtcgtaagt tgtctgcctg tttttctcaa
     8941 tctgcccctt ttgtttgtac ctaatctgtt agtgaagata gccattacag ctctattcag
     9001 tttcatacaa tccagattta cattcgttgc aatctgataa taattttgca tacctaatac
     9061 cattgaatta taaagtcttg tttcttctaa ttccgttttc ccttttgagg gagaagcaat
     9121 tttctttgcc tgtgatacca gcttgtcttt ttggtttttg aattgtttat cacttatatg
     9181 tgatttaaca actaacttct ttcttctcgg tatcatttta atcttgaaac caagaaagtc
     9241 ggagtatctt tttctaacat ttacaattct tgttttttct tgtgatactt ccaattttaa
     9301 tcgttgttca atccattgag tgattgctat tttggctttt tcagcacttt ccttgtagcg
     9361 gcagaaaact ctaaaatcat ctgcataacg aaccatatac atttccttta actttgtttt
     9421 cttcatttct ttgtaagcgt tgcttttaca tgggctaccg cttttattga tatgaaccac
     9481 atagtttttt gtaacaggat tttcctgcca ttggctttct acccaatggt ctaactcatt
     9541 aagaacaatg tttgctagta gtggggatat tattccccct tgcggagttc ctttctctgg
     9601 atatgttatt gtaccgttag tcattttgat tggagctttt aatatccttt ttaaaatgaa
     9661 tatcaagtgc ttgtcccgta ttcccatagc ccatatctgt tttatcagct tggaatggtt
     9721 cacgttgtca aagaaaccct taatatcaaa ttcaatcaca taatgtagct ggctgatttg
     9781 taggcggtta taggttgctt ttattgcatt ttcaactgac ctattaggtc taaaaccata
     9841 gctgttttca ctaaatttag cttcgcagat tggttctaat acttgtttta tacattgttg
     9901 tataagcctg tcccacatac aaggaatacc tagaggtctg gttttaccat ttggttttgg
     9961 tatttctttt cgcctcactg gcttaggtcg atacccatgt ggactgcctg caacaatgta
    10021 tcttactttt ttgacaactg tttctgctgg caatttgcca atatctttaa ttattgtacc
    10081 gtctgttcct gctgttttac tgcctgcatt tgctttgata tttcgatatg ccagtaatat
    10141 attttctctc gataggataa tatccataag atgagtgaaa atatctccat tcttactttt
    10201 ggcatataaa tcatcaaagg tgttttgcat ttcgtaatat tcagcgtgtc ttaaatcttc
    10261 tacacacaat gtttcatttt tatttttagg cataaggctt cactccttta cttgaaattg
    10321 agtgagcttt tttatcttac tcgtaatcct tattgaaaca acataatact tttctaatat
    10381 atacacgact tgagggcatt cctccattct cattacaaga atttcttagg ttcgccctct
    10441 gcttttcagc attagttcaa ctgcttattg ttcttcgtca gtttattctc ttgatgagaa
    10501 cccaatacct ttcctcgttc cgataatctt atctatacat atatatcctt aggtcactag
    10561 ctataagcct gctggcttga taccgcctgt aacgttatat ggcatttcat aacctatatt
    10621 cttactttgc cacaccagct acgatttctc gtacctttgc atttctacaa agttcaaatt
    10681 tagacccgta cattcgctgt ttcgtcagtt ccttatagaa cattctaacc atagatattt
    10741 tatagacccc cgacctgttg gatacgctac ccacctctgg atagttttcg atagaagata
    10801 tatgttcatc aactattacg gtatctttca gccgtcttta ccgagcttca aacattctga
    10861 gtttcctcat acaatgcttg tcggaggctc agggcaggcg tttcagagcg ttacttcatc
    10921 attccacctg tcagattatc agttctccta ataaccaaac tttttcgttc ttttattagt
    10981 gccttagctt ttcactaagg aacgagtcgc acaaaggttt tgtccaaaat tcataaaaat
    11041 gttctcctct ctatattcaa tgaatttgta tttgagttat ttttttgttg ttatcacgtc
    11101 ctgttctttt actgactgtt gcttcaaaat ctgcttgtgt cggtctgtca gtttcgcatg
    11161 gtcgagaatg tcttttacaa cctgcgtctg gttgatttca tcaagtttaa tcgcaacctt
    11221 taaggtcggg gcaacttgat gagatagcca gttcagcgtc ctttggaagg agtaaggctc
    11281 tggttttgtg gttagtttta atcgttcacg attgttccca ataaaccaag cccattcttc
    11341 attcagtttc caatcagaac gaggtttgga atcgtcttta tctacaaaac ggatataccg
    11401 attgataatt ttaaaggcgg tatgctctgg attgtcatag acgagtaaat cacggactgc
    11461 ataataggca cgctcatttt tcaatcgaat ctcaaaacgg ttttttactt ctgcgtcttc
    11521 aatgggaata tcatttttct tgtactgctc gtagtccttt tcatagatac agaaataaac
    11581 ttcactttgt aatgaaccga tatagagggt gtttcccata cattcctttt cctctttgcg
    11641 taccagttcg ccactgcgat agcttttaaa actgcggaag acggagatac attcttcctg
    11701 ttggcacttt tcagtgagta cagggatatt taaaatccct gtcttatcgt taatggcaag
    11761 gtcaaggcgt ttcatcacac cgccagccac caaaacgtcc ataaagaact cataccagct
    11821 tctttgttgt gccagaagat agctttcaaa ttgtctgcac ccacgacctt tcaattccac
    11881 cagaactcct ttgtccagtt catgggagca aaggacgaat atgtcgccta aagcataatg
    11941 ctctgaataa gaatagaaac catagtcctc atgaagaaaa taggacagtt tcagttgtaa
    12001 gatgttttcg accacctgct gtacgtctgt tgtcggaaag cgaattctta cataatcaaa
    12061 cagcatttca aggggagcgt cgggattgaa gcgttccaga gcttcccaaa gggactgctg
    12121 taaatcctct gatggcttga cttttcctgt ttcaatatcg cttagatact gccttgtaat
    12181 accagtcgca acagctaaac ggttttgaga tagtccataa gccaagcgtt tttcttttaa
    12241 atgctgtaac caagtttgtt cattcagtaa aaatccctcc aatcaaaaag gcgtatgtca
    12301 acttttaaag cccatttgac atacgctgaa attttgtaaa tcccttgtaa ccaaaggatt
    12361 ttctaatgtt tttttgactg tttcctgtcg atttgtaccc ccctgttaga taccgagggg
    12421 ttaagtgctg gcgtggctat tgccacacca gccagcaaga tcagtccaca cctgcgactt
    12481 ccgcttcgca cgtcgcctgc gtggactgtc tgctgttgga taacttttta atttcctcca
    12541 agaaatcata tccttttggt acaaggggag tataaaactc tgatatgaca cttgttccta
    12601 catcaacata gccacgacct ttgattcgct ttaagaagaa atccttttgt acgtcactgc
    12661 caaacatcat gccatagccc atttcagaca tacgacctaa agccactctg aaattaaact
    12721 gatcacggat tccgtcgcct aaatattttg cgtctggacg ttgacaagcc agtattagaa
    12781 agaagccagc ttgacgacct aacatgacaa tctgtttcag cttattcata actgcggtgt
    12841 tttcttttgt tcccagcatt tccatgaaag cgacgtattc atcaaagatt aagaagtgtg
    12901 ccgggagacc taagtaagca taatttttgc cagtcttata gttcttcatc tgcttcattt
    12961 cctcactacg tttcatcatt tcttcataga atgtttcaat gcaagaaagc aagtcttctt
    13021 ttctatagta gacatttgcc atcacagaac ctaagtccgc aaggtcagca tttttcgggt
    13081 caagaatata cagttttgaa tctgtatgaa gcaaggcttc aatcagtgtc agtataaagt
    13141 aagttttacc gccacctgta ccaccagcaa tcaacatatg agggagctta tcatattccc
    13201 accatacgtt tttcattaag cgaagtttac catctttagc ttctacttca tcaatagaaa
    13261 tacgactggc tatggtgtca tagagcaaag tatattccac ataggaatcc tttaactctt
    13321 tatccgtcag ctcacagtac aagccactct ctaatttctt ttccaagtgt aagagttggt
    13381 cttgatattt tcccagcgtg atttccaccc gtatctgtat caagccattt ttaagtcgat
    13441 aatacatttt agggaagtag gttatctttt cctttgtacg accagcacta tctttaaaga
    13501 aaccctctgt tttgacctgt tcagattcat accacttgtt ttcaagtatc atctttgcca
    13561 gtttttgacg gtggtaaagt tgtttaaccg tatcatagcg aacccgtttg aatacaaacg
    13621 ctaccagcaa gcagataaga attgcgacac tgaaactgat aattaaatag ggaatgtcaa
    13681 tcttatctgc ttgtgatagg ttaaaatcct gccagttgat ctgctggatt gtcttcacat
    13741 gaaacagtcc gacaaccagc aggaaaacag gcaggagtga cgctatcgta aaatgaaaga
    13801 ctaaatcttt accagatggg cgaatccttt taccacgctg tttcatgcga aaaagtctcc
    13861 tttctaccta gcgactattt gtcttgtgtc ggttctttct ttgcttgtgg ttgagctttg
    13921 aatgaactag aatcctttgt cagcacaata tcgtctgcct tgatatacca gtcaacatct
    13981 gctccttgat aggtggcagt agcaacggtg tccgcaatgg gattgataag ttccacccgt
    14041 gcgttataat caaactcttt caaaggcacg ctggcaggaa tacttacttg aatcatgcgt
    14101 ccttgtcctt tggattttaa gtcataggta cgttccttga tttcatctga aaccgacccg
    14161 tcttcatttt ggattctcac ttcacgacgt agagcagaga atttcaattc tccaaaagtc
    14221 gtgtctttat ctaatacaat gccatttgct aatctcatca tttttcctct ctttctttat
    14281 tcttttatca tgtcgtcagc atgtaaaagg taatttgtaa aaccacgagt gccgattttg
    14341 tagccctctg cggtaatacg tggattgact aacttcacac gttcctcaaa gccgaaatgt
    14401 ttttcgccag cttcagcagg aagcaccacc acaatatcat ctgctctttg aacatcagaa
    14461 tagagattat agcttcttga taagacagtt agccgtccgt tgattcttcg ctgaacgact
    14521 ttatcctcgc cagcaaattc taaattgccg aatgtttttt ccatgttggg aatcacaaat
    14581 ttaagttcca tatttttacc tatcctttct tttttattgg ctgaatgaat gtttgatggt
    14641 cttaaagagt ggggaacgac cttttgattc ttgatttttt gttttcataa gttcacttcc
    14701 tttcaaaatc gggtaaaaaa atagacacct cattttttga agtgtctacc tattaaatat
    14761 tcaaatttta ttggaagtat ctttatatct tcacttttca aggataaatc gtcgtatcaa
    14821 agctcattca taagtagtaa attagtagta aattgagtgg ttttgacctt gataaagtgt
    14881 gataagtcca gtttttatgc ggataactag atttttatgc tatttttctc ttaaaaaata
    14941 tcattatttg tggtatggag cccccgcgtt gatccggaag gcacggtaga tttgctcgac
    15001 gaggatcagg cgcatcaatt gatgtggata cgtcattttg ccaaaagaga tctgagcatt
    15061 gcttcttttc atgacggctt cgctgagtcc taaagaaccg ccgataacaa aaacaaggtg
    15121 gctttttcct tggataccta attggtcgat ttgtttagca aaagattcgc ttgtgggatt
    15181 tttcccttca attgctaagc catagacgta ttcttgttct ttgattttcg ctaagatccg
    15241 ttctccttct ttttctttta cttgtctcat ttgcgcttcg cttaaattct ccggggcttt
    15301 ttcgtcagga acttcgatca attcgatttt cgcataggca ttcagccgtt tgacatactc
    15361 attgatacct tggatcaagt atttttcttt taattttcct actgaaataa ttttgatatt
    15421 catgttttct ctcctttgat cttcacgctc actttgttta ttataatcaa ttttttcgtc
    15481 tatatgttta ttttgactat ttttgttaaa aagatttccc caacagttat gcacaacatc
    15541 cacaggttta tccacagaaa acagcgttgt tttaccttat ttcatcacat tcattaggca
    15601 aacatacgtt ttataagaat ttatccactt tatacacagg ctgtggatat gttttatccc
    15661 ttatttttcc aatcctatcc gcgtagtttt acacaatatc tgtggaaaaa gaaaatcaaa
    15721 tattttcatc tgaaaacaat gatttttcct aaagtttttc ataaaaagtt caaagtctca
    15781 aagtagacta aagtcaacaa ataagactat actaacagta gataaatgaa tgtaattgga
    15841 ggaggaacac atggatagaa aaaatgtgac accaaagatg aaaaaaaata aaaataatag
    15901 cctctggcgt aagttgggtc tggggcttgt tggagggatc gttggaggac tactgacagc
    15961 tggcattttt tatgcagcga tgggcactgg caacaatagt tctactgcta caagcggcaa
    16021 tcaaaattct gccggtgaaa cagttgtgga aaatgtcaaa gtcaatgtag attctgatat
    16081 caccaaagcg gtagataaag ttcaagacgc tgtcgtttct gttatcaact tacaaagtca
    16141 aaaccaatca agcggttttg gcggattatt cgggcagcaa gaagaaagta gcagctcaga
    16201 tgatagtaat ttggaagctt atagtgaagg aagcggcgta atctacaaaa aagacgggaa
    16261 tactgcttat gtagtcacaa acaatcacgt agtagatgga cagcaaggtt tggaagtcat
    16321 gatgaaagac ggtacgaagg taaaagctga attagttgga acagatgcct attcagattt
    16381 agcggtgttg aagatcaatt cagacaaagt cgaaacggtt gcctcttttg gggactcaag
    16441 tgctttgaag gttggtgaac ctgcgattgc gattggttcc ccattaggat ctgaatatgc
    16501 gaattctgtc acttcaggaa tcatttcttc cttgaaccga caagtaacaa gtacgaatga
    16561 atcgaacgaa acagtcaata tcaatgcgat ccaaacagat gcagcgatca acccgggaaa
    16621 ttctggtggt cctttagtga atatcgaagg acaagttatc ggtatcaact caagtaagat
    16681 cgcaagtact tctgaatcga cttctaatgt aagcgtagaa ggaatgggat ttgccatccc
    16741 aagtaacgat gtagtgaata tcatcaacca actggaaaaa gacggaaaag tgacacgtcc
    16801 agctctaggt atcacaatgg tcgacttatc tgccgtttct actcagcaac aagaacaaat
    16861 cttgaagatt ccttcatctg taactaacgg tgtcatcgtg acaaatgtcc aaacagctac
    16921 accggcagaa aaagctgggt tgaaacaata cgacgtcatt actaagatcg atgacaaaga
    16981 agtttcttct ggtgtagaac ttcaatctgc tttgtataag aaaaaagtgg gagattctgt
    17041 caaaatcact tactatgaag gctcgaaaga aaaaacaact actgttgaat tgacgatcga
    17101 tcaatcggca ttaaaacaaa atcaaaatag tgaaaattaa taaaaaagag gttgtgacaa
    17161 agacttgtca caacctcttt attttggaaa tacttctccg actacggcat cctcaggcaa
    17221 tactaagatt cctttttttt ctggagcatt tggcaaatgc aattcacgag cagaacaaat
    17281 cattccatag ctggctaccc ctcgcaaagt tcctggccag atcatcattc catctggcat
    17341 catggctcct ggttttgcaa cgacaacttt ttgtccagct tcgatatttg gtgcaccgca
    17401 aacaatttgc aatactgtcc cattgtccac ttctgtctca gtaatcgata aatggtcaga
    17461 gtcaggatgc gggacgcatg tttttacata cccgacaacg atcttcggtt catgatcagc
    17521 ttcaagctgt tcttcgaatc ctgcttcttt aatcaatcga ttcaatttcg ctaattcttc
    17581 atctgttaag cttacttggc cgttcccttc aattgttaga tgatcggaga tatggaaaaa
    17641 gttccaagca acaacttgac cttgttcatc tttgatccga gcaacattcc atttacgttc
    17701 gacagtgttt tctgttcctt tatcgtcggc tatgataacc atcaaagtgt ctccgacgtg
    17761 tgctttgtta taagcaaaaa tcatgttctt tcctccatta tcctttgctg agatttatct
    17821 taacaaaaaa ttgcattcac tgcatgagat ttttttcatg ctttatttcc gaagaagctt
    17881 cttctggaac accatttatt cgtaacaagg gactgtgaca agacttttgt cacagtccct
    17941 ttactgtttg attaaaaagg ttatacaagt tccacttgct taattactcg gctgttcttc
    18001 ttcgtcagaa acgatcaaga catcacaagg tgaatgacgt atgacgtagc tggctacact
    18061 tcctgtcata aagcgttcga ctgcatttag tccagactgc ccaaccatga ttagatcgat
    18121 tgcatatttt tttggcaatt tgactgccat ggattcacga acagagccgt atgcaataat
    18181 tccttctata tttgtgtaat caacagattt tccatattct ttacattctt cgatcatttg
    18241 cttggctgtt tcagtttgct gatcgactag attttgatca ataggagcat agcccataaa
    18301 attataaaat tgctgatcga ttacgtttgc tacatatact ttcccattat tacggcgagc
    18361 cacttctaac gcttttttga aagcagcaag tgcttgttca ctaccgtcaa tacctactaa
    18421 aatgttctta tattcttgat tcatcttgac ccctcctaac agatgtcagc cttttattac
    18481 actttctagg aacgattcga tttcctgttt tgttttacga tctttattca ctagacgacc
    18541 taattctttt ccgtcttgga tcacgacaaa acttgggata ccaaaaatgt tccattcagc
    18601 ggctacatct atgtacttgt cacggtctac ttcaataaat tgccaatcag aaaagtcatt
    18661 ttcgatttca ggcatttgcg gtttgataaa acggcagtct ccgcaccagc cggcagtaaa
    18721 gaaaaataca ctttttccag tttctacgta gcctgctaat tcttctaaac tatttgggat
    18781 aatcattctt tttcctctac tttctgttta tgtatttttc aattaaatta tacacctttc
    18841 tttcgaacta acaaacattg atcctctttt tataaaaaaa atctgacaaa aggttgcttt
    18901 tgccagattt tatagtttca ctatcgcgtt atttcccgta tacgatcgtg ttcactgttg
    18961 atttatctaa acctttcaat gtttgaatca acatttctcg tgcagcttca aaatcgcgaa
    19021 tactgaacat cgtttgatgc gtatggatat aacgtcccac tacgccaatc actgtacttg
    19081 ggattccttc attttgtgta tgagcagcac ctgcatctgt accgcctttt gaaacaaagt
    19141 attgataagg gatgttgttt gtttcagcga tatctagcaa gtactcacgc aaacgaggaa
    19201 gcatgatcaa acctggatct tggatacgca tcaatgtacc ttctcctaaa tgtccgaatg
    19261 tgccattttt cgtcactgtg tcatctgctg cagagcagtc tactgcaaag aacagatctg
    19321 gcttgaattt attgacagaa gctttagaac cacgcaagcc tacttcttct tggacattcg
    19381 cgcctgcaat caatgtatga cctaatgttt cattttgtaa cgcttctaaa gcttctaata
    19441 ccattgtaca gccatagcgg ttgtcccacg atttgctgat gatattcttc ccgttggctg
    19501 ttttgatcgt ttcagcgtaa ggaacgattg tgtctcctgg aagaacaccg taactcattg
    19561 cctcttctct tgattcaaac ccagcatcga acaaaatatc tgttacttct actgattttt
    19621 gtccgcttgt tcctcgtaat aaatgtgggg gaacggaaga agaaatacat ggataattct
    19681 taccagtaga ggttttaagt gtaaaacgtt gagcagaaac aacgtaaggg ttccatccgc
    19741 ctagaggtac gactttaaaa agcccgtttt cttggatttg tgtcagcatg aatccgactt
    19801 catccatatg tgctgcgacc attacacgag gtgcatccgc ttcttcatgg tggcgcagcc
    19861 caaaaatgcc gcccaaacca tctaactgta actcatctac cagcggttcc atatgacttt
    19921 ccatataggc gcgaacgtct tgttcaaaac cgcttgttcc ttgtaattct gttaactctt
    19981 tgattcgttg aaatgttttt tcttccatat gctattcgtc taaatttcag actaaactcc
    20041 tctcagactt atattgatct gcggataaaa tatgattttt tctgcagacc gatcgtattt
    20101 attatagctt attttttctg gtagcggtta tttatttcaa agaaaatatg agagtgtggt
    20161 aaaataaaca caaagagtag caagtgagaa gaaggaggta tatccacatg tatgaagaaa
    20221 gcgaattaag ctattttaaa ggcgggttag ccgttgggat cggtctagga ttattgagtg
    20281 gggtagcttc aacgatttgg tatcatcgca aaaaagtgtt atcagcagac caagtgcttg
    20341 aaaatatcaa aacatctttt ttaaaagaag gcgcaatcga aggtgcttgg atctcttttg
    20401 aaaaagaacc tattcggaaa ttcgccgttc ggtcgagtgc ttatcggggt gggctttccc
    20461 ggatagaaga tggcgaaact gtttattatg aatttttagc agatgctcat acaggaaccg
    20521 tattagacat ttcaagaaaa aagggcgcaa tagattaata cgtcaaaaaa atgaaataac
    20581 gaatacgcac ccactatcta aaagagaggt atcctatcct tcttttatag tgggtgattt
    20641 ttataaaaat agggctattt cctcttggaa tagctagtat ttgtagttat tatacggtat
    20701 tcttgaaata agattagttt tattatataa ggagagtgac aaatggaatc acgtgaaaaa
    20761 attgccgtgc tcattccttg ttataacgaa gaggcgacaa tttcaactgt tattgaagat
    20821 tttaaaaggg aattaccaga agcagatatt tatgtctatg ataataattc gaccgatcga
    20881 acatacgaat tggccgttca aggcggagca atcgtaaaga aagaaccacg tcaaggaaaa
    20941 gggaatgtaa tccgtcaaat gttttttgat attgatgccg attattattt gatggtagat
    21001 ggtgatgata cttatcctgc agaagctgca catggtttgc ttgagaaatt acgttctggc
    21061 gaagcagata tggtcattgg cgatcgtcta tcaaatggaa cctattttga tgaaaataag
    21121 cgtcctttcc atgattttgg gaataatctg gttaaaaata caattactta cttatataaa
    21181 acaaaaattc gcgatgtcat gaccggctat cgaggattca atcgaatttt tgtcaaaagc
    21241 ttccctatta tgagttctgg ttttcaaatc gaaacagaat tgacgattca tgctttagat
    21301 aaaaaattca agttcgttga gattccaatc gattatcgcg atcgtcctga aggtagcgaa
    21361 tcaaaattga atacattctc tgacggattc aaagtgatca tgatgatcat caaaatgtgc
    21421 aaagattata aacctttgct tttctttggg atctggacca tcttcttctt tttatttgga
    21481 ttggtcatgg ggattcctgt gattcgtgaa tatatgctga caagctttat tacacgcatc
    21541 ccttctgcga ttttaagtac tggattgatg actttagccc ttctttcatt agtaacaggg
    21601 ttgattttgg atacggtcgt cacaaatgcc aagaaagaat atgaattgaa tttataccat
    21661 gtctaccacg aatatcaaaa taaagaaatg aagtaggagg ccttttttat gcataagaaa
    21721 aaggagaatc tatttcctac tttttttgca actttatttg cgtcaggttt tgcttttttt
    21781 acttcttatg gtctaggaac tttgaatcca acagtaatca ttggtttagc catggttttg
    21841 ctacttgctt ttaagcaata tggaatagag ttgttttcaa taaaaaacaa agttgcagct
    21901 attgcccgat tgtttttttc tgcagctttt gctcttacac tttctattgg cagacagata
    21961 caatttcagt atgtctcagc aaactataca aagacaacga ttgctgatgg aagtattttt
    22021 tactttcttg tttatttctc catttttgtg tattcttttt
//
LOCUS       DAYNVV010000044        21822 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.044, whole genome shotgun sequence.
ACCESSION   DAYNVV010000044 DAYNVV010000000
VERSION     DAYNVV010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21822
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.044"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            3..551
                     /gene="hslV"
                     /locus_tag="ACGXWR_001912"
     CDS             3..551
                     /gene="hslV"
                     /locus_tag="ACGXWR_001912"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HslVU peptidase proteolytic subunit"
                     /protein_id="HFK0803465.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            565..1965
                     /gene="hslU"
                     /locus_tag="ACGXWR_001913"
     CDS             565..1965
                     /gene="hslU"
                     /locus_tag="ACGXWR_001913"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HFK0803466.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            1983..2774
                     /gene="codY"
                     /locus_tag="ACGXWR_001914"
     CDS             1983..2774
                     /gene="codY"
                     /locus_tag="ACGXWR_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HFK0803467.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            2856..3731
                     /locus_tag="ACGXWR_001915"
     CDS             2856..3731
                     /locus_tag="ACGXWR_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFK0803468.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(3863..4501)
                     /gene="plsY"
                     /locus_tag="ACGXWR_001916"
     CDS             complement(3863..4501)
                     /gene="plsY"
                     /locus_tag="ACGXWR_001916"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HFK0803469.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            4628..5062
                     /locus_tag="ACGXWR_001917"
     CDS             4628..5062
                     /locus_tag="ACGXWR_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HFK0803470.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            5228..7273
                     /gene="parE"
                     /locus_tag="ACGXWR_001918"
     CDS             5228..7273
                     /gene="parE"
                     /locus_tag="ACGXWR_001918"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HFK0803471.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            7285..9735
                     /gene="parC"
                     /locus_tag="ACGXWR_001919"
     CDS             7285..9735
                     /gene="parC"
                     /locus_tag="ACGXWR_001919"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HFK0803472.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            10012..12243
                     /gene="pflB"
                     /locus_tag="ACGXWR_001920"
     CDS             10012..12243
                     /gene="pflB"
                     /locus_tag="ACGXWR_001920"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HFK0803473.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            12487..13248
                     /gene="pflA"
                     /locus_tag="ACGXWR_001921"
     CDS             12487..13248
                     /gene="pflA"
                     /locus_tag="ACGXWR_001921"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HFK0803474.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            13333..14259
                     /locus_tag="ACGXWR_001922"
     CDS             13333..14259
                     /locus_tag="ACGXWR_001922"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HFK0803475.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            14441..15334
                     /locus_tag="ACGXWR_001923"
     CDS             14441..15334
                     /locus_tag="ACGXWR_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HFK0803476.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            15468..15593
                     /locus_tag="ACGXWR_001924"
     CDS             15468..15593
                     /locus_tag="ACGXWR_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HFK0803477.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(15727..16359)
                     /locus_tag="ACGXWR_001925"
     CDS             complement(15727..16359)
                     /locus_tag="ACGXWR_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803478.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(16507..17049)
                     /locus_tag="ACGXWR_001926"
     CDS             complement(16507..17049)
                     /locus_tag="ACGXWR_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HFK0803479.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            17184..17573
                     /locus_tag="ACGXWR_001927"
     CDS             17184..17573
                     /locus_tag="ACGXWR_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803480.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            17577..18341
                     /locus_tag="ACGXWR_001928"
     CDS             17577..18341
                     /locus_tag="ACGXWR_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFK0803481.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            18470..19417
                     /locus_tag="ACGXWR_001929"
     CDS             18470..19417
                     /locus_tag="ACGXWR_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFK0803482.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            19547..20287
                     /locus_tag="ACGXWR_001930"
     CDS             19547..20287
                     /locus_tag="ACGXWR_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803483.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(20578..21246)
                     /locus_tag="ACGXWR_001931"
     CDS             complement(20578..21246)
                     /locus_tag="ACGXWR_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFK0803484.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            21380..21667
                     /locus_tag="ACGXWR_001932"
     CDS             21380..21667
                     /locus_tag="ACGXWR_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803485.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
BASE COUNT         7692 a         3699 c         4536 g         5895 t
ORIGIN      
        1 acatggtcga atcaccattt cattcaacca ctatctgtgc cgtcgaaaaa gacgggaaat
       61 ttgctatggc tggagatggc caagtaacaa tgggtgaatc tgttgtcatg aaaggcactg
      121 caaagaaagt acgacgtatc tacaatggag aagttgttgt aggtttcgcc ggaagtgttg
      181 cagatgcgtt tactttagaa gaaaaatttg aaggcaaact aaacgaatat aacgggaatc
      241 tacaacgcgc agctgtcgaa ttagctcaag aatggcggac acagcaatct atgcaaaaac
      301 ttgaagcgat gctgatcgta atgaatgata aagaaatgct tcttgtttca ggtacaggag
      361 aagttatcac accagatgat ggtatcttag ctatcggatc aggagggaat tttgcgttgg
      421 ctgcagcccg agcaatgaaa aactatgctc aaaacgacat gagtgcgaaa gaaattgcag
      481 aaaatgcgtt aaatattgcc gcagatatct gtatctttac taatcataat attatcgtag
      541 aagaactgta agaggtgagt agatatgtat gaattaaaac aaacaccaag acaaatcgta
      601 agtgaattag atgaatatat cgtaggacag cacgcagcaa aaaaatctgt tgccgttgct
      661 ttgcgtaacc gctatcgccg tttgcagtta gatgaaaaaa tgcaacaaga tattacacca
      721 aaaaatatgc tgatgatcgg acctacaggg gtcggtaaaa cagaaatcgc acgacgtttg
      781 gcaaaaatcg tcaatgcacc atttgtcaaa gtcgaagcaa caaaatttac tgaagtcggt
      841 tatgtcggaa gagatgtaga atcaatggtt cgggatttag tagaaaatgc gatccaaatc
      901 gtagaaaaag agcagtacag ccgtgtatac acaagtgcta aaaaaaatgc agaaaaacgt
      961 ttggtaaaaa tcttggtacc tggtatcaaa aaagaacaga aacaatccac taatcaattt
     1021 gaacaaatga tgaatctttt taatgctagt cagcaaaata ccgctgaacc gcaagaagaa
     1081 gtgacagaag atattcgaat caatcgccgt acagtcttgg aacaactaca aaagggttta
     1141 ctggatagtc gtgaagtaac cattgaagtt gaagaccaaa agaaacctgc accaatgatg
     1201 aacaatggat tggagcaaat ggggatcgac ctaaatgaaa ctctaggtgc tttgacaccg
     1261 aagaaaaaag tggaacggac ggtaacagtc aaagaagctt tagagttatt gatcaaggaa
     1321 gaatcagcaa aattagtcaa ggatgctgat atccatagtg aggcaatcaa attagcggaa
     1381 gaaagtggaa ttatttttat cgatgaaatc gataagatca cttctaaatc acagcaatct
     1441 ggagaagtat ccagagaagg cgtccaaaga gacatattgc caattgtcga aggttcacaa
     1501 gtaaacacaa aatacgggat catccaaaca gatcacgtcc tattcattgc ttcaggagct
     1561 ttccatttgt ctaaaccaag tgatctaatt ccagaacttc aaggacgctt cccgatacgg
     1621 gtagaattag atgatttgac agctgaagat tttgtgaaga ttctgaccga accaaataat
     1681 gctttagtaa aacaatacgt cgcgttgatc ggtacagaaa atgtgtcagt tacgtttaca
     1741 aaagaagcaa ttgaacggat cgctcaaatc gctttcgatg tcaaccgtga cacagataat
     1801 atcggcgcac gcagactgca taccattttg gaaaaactac tagaagatct attatttgaa
     1861 gcaccagata tgcaaatggg agaaataacg atcacagaag catatgtgga tgacaaactt
     1921 ggctcaattg cggcaaatga agatttaagt cgctatattt tataaaaaat cggaggacga
     1981 caatgacaga cttgctaacg aaaacccgca agataaacac acttttgcag caaaagaata
     2041 cttttgacat gcaagcagat ttgccttacg ataaaatggc tgtcacacta ggtggtattc
     2101 ttgacagcaa cacctatatc ataggaagtg acggagtatt actaggttat aatgaacgtc
     2161 acgatgtgaa caatgaacga atcaaaacaa tgtttgttga gaaacaattt cctgaatctt
     2221 atactgatac agtggcacag ttgatgaaaa ctgaagctaa tatcccaatt actagtgata
     2281 ttactgcatt tccggtagag tcaagagaga aatatccatt tggtctgacg actgtcgttc
     2341 cgatctttgg agctggcgaa cgtttgggta cgattatctt atctcgtatg gaacaatcgt
     2401 ttgcagatga cgatctagtc ttagcagaat atggagctac ggttgtcggt atgcagatcc
     2461 tttatcagaa gtctcgaagc atcgaagcag atgtacggag tgcaacggct gtccaaatgg
     2521 caatcaacac attatcttat agcgaattga aggctgtaca agctatcttt gaagcattgg
     2581 atggagatga aggtcgtctg actgcttcta atattgccga tagtatcggc atcactcgtt
     2641 ctgtgatcgt caatgcttta cgaaaattgg aatcagctgg aatcattgaa tctcgttcgt
     2701 taggcatgaa gggaacttat ttaaaagtat tgaattcccg ttttaaagac gagttagcaa
     2761 aacacagtta ttagaagtaa ggggactggg gcagatagaa atgtttgttc cagccttccc
     2821 attttaaaaa gtaagtcgaa gttggaggaa tggcaatgac tgttattatt caaaatgacc
     2881 agctgatcgc cgaaatcgct gaacacggtg cggaattgat cagtctgaaa tcaaaagaac
     2941 atggtttaga gtatatctgg caaggtgatc cagcgtattg gggcagacat gcaccggttt
     3001 tattcccttt tgttggacgt ttaaaagatg atcagtatgt ttatcaaggg aaaacatatc
     3061 aaatggggca acacggattt gctcgggata tggattttga agtcattgaa catggacaag
     3121 aaatggctag tttcatctta aggagtacgc cggagacatt agaaaagtat ccatttgatt
     3181 ttgaattagt gatcagctat gaattaggag gagacggcat cacggttcat tatcaagtgg
     3241 caaataccgg tgaaaaagaa atgttctttt ctatcggtgg acatcctgct ttcaatgtac
     3301 ctcttgaaga aggattgtca tttgaagatt tctatctggc attttctcca ttgaaatcaa
     3361 gattacgcct accattgaaa ggcccattca tcgatatgga tcaaaagacg ttaggtcaga
     3421 caaatacgaa tctggctttg aatcgtgaac tttttgagca agatgccttg gtttttgaaa
     3481 caaggggtct aaatgcgtac gccattcgaa gtgaaaaatc ttcccatagc gtaactttaa
     3541 gctataaaga tatgccttat gtagggatct ggtctcctta tccaaaagaa gcgcctttcg
     3601 tttgtatcga accgtggtgc ggaatcgctg acacggtgaa cagtagtgga aacttgatgg
     3661 aaaaagtagg gatcaatcaa ctaggtgccc atgaaatctt caagacaaaa tattccatca
     3721 cagtgaagta agaggttgtg accgagaagt tagcagggaa caccgtttac caaggtgtgt
     3781 aaaaaagcta tcctgtaagt aataagggag tgtgacatcg atttgtcaca ctcccgtttt
     3841 atctctttgg aatgaaaaag tatcaggatt ttttcttgct gctattcaaa ccaaacggga
     3901 ttcgactttc agtatggttt ctgatacgct tgatattgtc tttatgccga taaaagataa
     3961 aggaagaaac taaaaaggca atgatcgtca gtaaccaatt gggcttagcc aaaatcacag
     4021 gagctacata aggaaggacg atcgtagata aagtgatcaa tactgcactg atcatactgc
     4081 tcaaactcac catacttgta caaaataaac taacgataaa gatgatacaa gaataaacaa
     4141 aaaatacagg attaaatcct aaaagcattc ctgcacttgt cgcaacagct tttcctcctt
     4201 tgaacccagc aaaaatcgga aatgtatggc caagaatggc gcatacccca aaccaaagag
     4261 ggttaatccc agaaaggtgg aagatcatcg gcaaacaagt agccaatgta ccttttaaaa
     4321 tatccataag caggacaaca atcccggctg ttttgcctaa tacacgaaat gtattggtcg
     4381 ttccagtatt accgctcccg tgttgtcgga tatctttttt gaaaaacaat ttgccaatcc
     4441 agacaccgga aggaatagaa cctaaaagat atgctaaaat aagtaataag atcaatttca
     4501 ttttttaccc tctttcaagt tgaaaactat cctttatttt agcatgaata ggtaacagga
     4561 acaattgaaa aaatgaaaga tacaagtata atagatggaa taaaaagaaa agcaaggggt
     4621 ggcagaaatg tctgtaaaaa atccaacaca agaaacgatt ttcaactatt tggaagaagc
     4681 aaaaaatatt gccgtcgtag gcttgagcaa taaaccagaa cgaacaagtt acatggttgc
     4741 acaggtattg caagacaatg gatataaaat cataccagta aatccattat tggctggtga
     4801 agaaattcta ggcgagaaag tctatgcgaa tttgacagaa atcgatgatc caatcgatat
     4861 cgtagatgta tttagacgga gtgaattttt acctgaaata gcaggtgatt ttttgaaaac
     4921 tgatgctaaa gtgttctggg cacaattagg gattgaaaac aaagaagcag ctgagatgct
     4981 aagaaaagca ggacgtacag atatcgtaat ggatcgttgt attaagattg aacttggtaa
     5041 gttgaaagaa aaccaaaaat aaaaatgacc acaaagaaga gatgatcgat agaggggaat
     5101 gtcgaaaaag cggttaggag ataattaaaa ttgatttctc gtctaccctc ttttttttca
     5161 cgaccttttc tagtatgata atcgtggtgc ggttttgccg caaagtatta ttgaaggagc
     5221 gtttgccttg gcaaaaaaag taaacaacga atacaatgac tcgtccatcc aagtattgga
     5281 aggattagag gcagttagaa aaagaccagg gatgtacatt ggatccactg acagccgagg
     5341 cttgcatcat ttagtctatg aaatcgtcga taatgcagtt gacgaagcat tatcaggtta
     5401 tggcagtgag attgatgtga ccatccatga agacaatagt ataactgttg cagatagcgg
     5461 acgtgggatg cctgtaggaa tgcatgcttc cggaatacca acagttgaag tgatttttac
     5521 tgtgctgcat gctggcggaa agtttggtca aggagggtac aaaacttctg gtggactgca
     5581 cggtgtagga gccagtgtgg taaatgcctt atcgaaatgg ctaattgtaa cgatcgttag
     5641 agatggcgta gagtatcagc agaaatttaa aaacggcggt aaacctgacg gtactttgaa
     5701 aaagatagga aaaacaaaaa aagcaaacgg gacgactgtc cattttttac cagatgatac
     5761 aatattcagt acaacgaaat tttcatatga aattttagcc gaacggttaa gagaatctgc
     5821 ctttcttcta aaaggcgtta aaatctctct ttctgatctt cgtggagaag aaccagtcaa
     5881 ggaaattttt cattacgaag aaggaatcaa agaatttgtt gattatctga atgaagaaaa
     5941 agatacattg acaccagttg tttatttttc aggagaaaaa gaaggtatcg aagtagaggt
     6001 cgcttatcaa tacaatgacg gttattcaga aaatgtttta tcttttgtca ataacgttcg
     6061 gacaaaagat gggggaaccc atgaagctgg tatgaaagcg gcgatgacga aatcttataa
     6121 tgaatatgcg agaaaagttg gtttgctgaa agaacgggac aagaatctgg aaggtagtga
     6181 tttcagagaa gggttagctg ctgtactttc tatccgtgta cctgaaaatc ttctgcaatt
     6241 tgaagggcaa acaaaagaaa aacttggtac gccagttgct cgtaccgtag tagataacgt
     6301 catcagtgaa caaatgggct tttatttgca ggaaaatagc gaaatgagcc agatgttggt
     6361 ccgtaaagca atcaaagcca gagaagcgag agaagcagca cgtaaagcca gagaagaaag
     6421 ccgaaatggg aagaagcgta aaaaaggcga atctcttctt tcaggaaaat tgacacccgc
     6481 acaatcccga aaccctaaga aaaatgaatt gtatttagtc gaaggggatt ctgctggcgg
     6541 atctgctaaa caaggaagag acagaaagtt ccaagcaatt ctacctttac gaggaaaagt
     6601 catcaatacc gaaaaagcta aaatgcaaga tatcttgaaa aatgaagaaa tcaatacgat
     6661 gatctatacg attggtgcag gagtcggtcc tgagttttct atcgaagact gtaattacga
     6721 caaagtaatc atcatgaccg atgcggatac agacggcgcc catattcaag tattactgct
     6781 tactttcttt tatcgttata tgaaaccgct gattgaagct gggaaagtat atatcgcgtt
     6841 accgccttta tataaagtat ccaaaggaca aggaaagaag caagtcattg aatatgcgtg
     6901 gacagatgac gaattggcag caatgattaa aaaagtcggc aaaggatata tgctgcagcg
     6961 atataaagga cttggagaga tgaatgcgga acaattgtgg gaaacaacga tggatccgac
     7021 ttcccgtacg ttgatccgcg tccgtatcga tgatgctgcg caagctgaac gtcgagtaac
     7081 cacactgatg ggtgacaaag tagaacctcg aagaaaatgg atcgaaaatc acgtgcaatt
     7141 tacgctcgaa gaagatggca gtatcttaga taaaaaagag gatactgaaa tctctccttc
     7201 agtttctaat gatttattag atgaagaacg agcagataaa aatgaaaaca atcagttatt
     7261 tgaagtagaa taggaggtca cctgatggaa aatcgacaag aagtacaaga attaacttta
     7321 gaagaagtga tgggtgaccg cttcggacgt tattccaaat atattatcca agaacgtgca
     7381 ctgcctgata tccgtgatgg attgaagcca gtgcaacgcc ggatattatt tgccatgaac
     7441 aaagatggca atacgtatga caaaggattc cgtaaatcag caaaatctgt cggaaatatc
     7501 atggggaatt atcatcctca tggtgacatc agtatttatg aagcgatggt ccgcatgagc
     7561 caagactgga agttgcggga agtactgatc gaaatgcacg ggaataacgg gagtatggac
     7621 ggtgatccac ctgctgcgat gcgttatact gaagccagat tatccaagtt aagtggagag
     7681 atgctagcag atatcgagaa agaaacagtc gatctcgtgt ggaattttga tgatacagaa
     7741 aaagaaccaa cagtccttcc agctcgatac ccaaaccttc tcgtcaatgg atcgacaggt
     7801 atatctgctg gatatgcaac agaaatcccg actcataact tagctgaagt gatcgatggc
     7861 acaatctata tgatcgatca tccacaagcg agccttgaaa aattgatgga atatattcct
     7921 ggacctgact ttccaacagg agggatcttg caaggaaaag atgaaatcaa aaaagcttat
     7981 gaaacaggac gaggaaaagt tattcttcgt tcgaaaacaa agatagaggc aatgaagggt
     8041 aataaacagc aaatcgtgat cacagaaatc ccatatgaag taaataaagc gaccttggtg
     8101 aaaaaaatgg atgagatccg tttgaataag aaaatcgatg gaatagctga agtacgagat
     8161 gaaagtgata gaacaggtct gcaaattgtc gtcgaattga aaaaagacgc caatgctcaa
     8221 ggaattttga attatttgtt caaaaacact gagctacaga tcaattacaa tttcaatatg
     8281 gtcgctatcg accatatgac tccgcatcaa gttggactga aagacatttt aagaagttat
     8341 atcgagcatc gaaagcaagt cataacaaaa cgtagtcaat tcgatttagc caaagctcaa
     8401 aaaagacagc atatcgtaga aggattgatg aaagctttat cgattctgga tgaagtaatc
     8461 gcaacgattc gtgaaagtaa agacaaaaaa gacgccaaaa agaatttagt cgacgtcttt
     8521 caatttacag aagaacaagc agaagcaatt gtcacattgc aattataccg tttgacgaac
     8581 acggatatca cagagcttca aaaggaatcc gaaagcttga ttgcgcaaat cacagagttg
     8641 aataaaatcc tttcaaatga caaagagctt ttctctgtta tgaaaaaaga attgcgagaa
     8701 gtgaaaaaaa attattcttc cgctcgtcta acgacaatcg aagacgaaat cgaagaaatc
     8761 aaaattgata cgcaagtctt agtggcacaa gaagacgtaa ttgtcagtgt gacgcgagaa
     8821 ggctatgtga agcgaacaag ccttcgttct tatagtgctt ccaaaccaga agaaatcggg
     8881 atgcgagaag gcgactactt gctatactca ggtgaattga gtacattgga ccatgttctt
     8941 ctgatcacaa ataaagcaaa tgtgatctac cgccctgtcc atgaactacc cgatttgaaa
     9001 tggaaagatg ctggtgagca catttctcaa acaatctcca atctgtctgt agacgaatcg
     9061 attttagctg ttttcccata tcaaaaaatt caagcagaga aaacatttgt attcatcagc
     9121 aagaatggat tgatcaagca aacacgaatg acagagttcg aaccatggcg cacctataag
     9181 agccgtccgc tcagctgtat gaagctaaag gcggaagaag atgaactgat tgctgtgtat
     9241 ctgaaagaag atcagccagg cttagatgtt ttcttagtaa cgcatcaagg aatgggtttg
     9301 cgctatcctt taacagatgt tcccgttgtt ggagcaaagg cagctggagt gaagtctatg
     9361 aatttgaaag atggagatag gattatcaac gggctgcttg tgttagcaga aggtgatacg
     9421 ccgatcgtaa tcgttactca gcgaggagct gttaaacgca tgcttgctca agaaatcagc
     9481 caaacttcac gtgcgaagcg gggagtgacg gtcatgcgtg agctgaaaaa aaatccgcac
     9541 cgtattatct atatgtcgga aggaagatca aaagaaataa ccttgatgaa tcaaaaaggg
     9601 cagcagttaa cgattgaccc aactgatttc cctataggtg atcgaacatc gaatggatca
     9661 tttgcgatgg atgagaaaaa aggtggagaa gtcatcgaag ttatcgatgc tcctgagatt
     9721 ttcatcgagt cgtaactgtt gtagtatttt aatgaagaga cgccatctgt attaatacag
     9781 gtggcgtctc tttttcattc atttttaata aatccttata cgtttgcaaa aaaagatgaa
     9841 agtgttcaca atgcttaaat gttggtatgt caacgttgat ttaaatatat gtaaataaaa
     9901 cataaaaatt gttaaataaa aaacaagaaa acccttgcaa agatagggtg ctgtgttata
     9961 ctaatcacgt aaaaactgtt acataaaaca gaaatttagg aggtccatac aatggagcaa
    10021 tggaatggat ttaaaggtac caaatggaaa gaaggcgtag acactagaga ctttattcaa
    10081 aataactaca ctgaatatcg cggtgatgac agctttttgg aaggcccaac agaagcaaca
    10141 gaaaaattat gggatgaatt gcaaaagtta aatgatatcc aattcgagcg taacggtgtc
    10201 tatgatatgg acacagaaat cgtatcaact attacttcac acgatgcagg ctatttggat
    10261 aaagatttgg aaaaaatcgt cggtctacag acagacaaac ctttgaaaca agcattcatg
    10321 ccgttcggcg gaatcaatat ggctaacaat gcgctaaaaa gcaatggcta tacaccaaac
    10381 gatgaattga cacatatttt cactgactgg cgcaaaacac ataatcaagg tgtatttgac
    10441 gcttatactg ctgaaatgcg tgctgctcgt aaaaacaaaa tcattacagg gcttccagac
    10501 gcttacggtc gcggacgtat catcggtgac tatcgtcgtg tggcattgta tggaatcgac
    10561 tatttgatgg aacaaaagaa aaaagatcat gatatgactg gttatcatac aatgagtgaa
    10621 gaagtgattc gtttacgtga agaaatcact gaacaatatc gtgcattagc gcaaatgaaa
    10681 gaaatggctg cgaaatatgg ctatgatatt tctaaaccag ctgcaaatgc aaaagaagct
    10741 gtccaatggc tatacttcgg atatttagca gcaatcaaat cacaaaatgg tgctgcgatg
    10801 tcaatcggac gtatctcagc attccttgat atctatatcc aacgtgattt ggataatgga
    10861 gtaatcacag aaaaagaagc acaagaattg atcgaccact tagtaatgaa attacgtatg
    10921 gtcaaattcg cgcgtacacc tgaatataac caattattct caggattccc tatctgggct
    10981 actttatcca ttgcaggtat gggattagat ggtcgttcat tagttacaaa gaatgatttc
    11041 cgtctgcttc atacattaac aaatatggga ccttcaccag aaccaaactt gactgttttg
    11101 tattctgaac accttccaga aggattcaga acatatgcta gcagaatcgc tatcgaaagt
    11161 tcttcgattc aattcgaaaa tgataatcag cttcgtgaac aatggggttc tgatgattgt
    11221 gcgattgctt gctgtgtatc aggaacagtt gtcggaaaag acatgcaatt ctttggcgct
    11281 cgtgctaact tggctaaaac actattatat gccatcaatg gcggagtcga tgaagtgact
    11341 ggcgcccaag ttggaccaga atatcgtcca atcacatcag aaatactaga ctttgaagaa
    11401 gtgaaacata acttcatgaa tatgatggat tggttagcag aactatatgt caatacgttg
    11461 aacatcattc attatatgca tgataaatat tcttatgaag cagctcagct ggctttgatg
    11521 gattctgact tgcaacgcac atttgctaca ggtattgctg ggatctctca tgcggcagac
    11581 agcttgtcag cgatcaaata tgcaaaagta aaagcaatcc gtaatgaaaa aggaatagca
    11641 gttgattttg aagtggatgg cgacttccct aaatacggaa atgatgatga ccgtgcagat
    11701 gaattagttt catggatctt ggaatacttc atgggacaaa tcaaacgtca taaaacttac
    11761 cgcaactcaa aaccaacaac ttcattattg acgattactt caaatgttgt ttacggtaaa
    11821 aatacaggaa atactcctga tggccgtgaa gctggaaaac cacttgcgcc aggagcaaat
    11881 ccaagttaca atgcggaaca aagtgggtta ttagctagcc tgaactcaac agctaaaatg
    11941 aattacggct gtgcattgga tggaatttca aatacccaaa caatcaatcc ttcaggtctt
    12001 ggaaaagaac aagatacaag aatcgaaaac ttgcgtaatg tcttagatgg atacttctca
    12061 aaaggagctt atcatttgaa tgtcaatgta ttcagtaatg atttattgcg tgatgcaatg
    12121 gaaaatccaa tgaaatatcc gaacttgacg atccgggtat ctggttatgc agttaaattc
    12181 cgtgacttga caagagaaca acaattagat gtcttgatga gaacttcaca cgacagaatg
    12241 taaaaagttc gtgaaaaaag tttttcgact tagcgtcgaa aggacgttga atagccatcg
    12301 catcaaaatc gaataatcag tatgcttatt tgaaagaaac gatttacagg ggcaggactt
    12361 gtatgttccg tccctgtaaa ttttacacat aacgaagcgg caattgcgaa aaattttgtt
    12421 cagaaagctt cgcttcgaca gctaacttgt acttaaaatg aaatcaaaga aaagatgtga
    12481 acttaaatgg aagaaaaaac aatcggctat gttcattcta tcgaaacttt cggttcagta
    12541 gacggacctg gactgcgctt tgtcgtgttt atgcaaggat gccgcatgcg ttgccaattt
    12601 tgtcacaatc cagatacttg gaatattggc ggagggaaag aatacacagc agatgaactt
    12661 ttagataaag cagaacgctt cagaccttac tggggagata aaggtggtat tactgttagt
    12721 ggtggagaac ctctattgca gatcgatttt ttgatcgaac tatttaaaaa agcaaaagag
    12781 cggaagatgc atactacatt ggatacatgc ggaaaacctt ttacgtatga agaacctttc
    12841 ttttcacgtt ttcaagaatt gatgaagtat acagatttac tgttatttga catcaaacac
    12901 atcgataatg aagagcataa aaaactaacg cattgggaca atgaaaatat tttagaaatg
    12961 gctcaatatt tgtcaaaaat caacaaaccg gtttggattc gccatgtact agttcctgag
    13021 cgaagtgatt atgatgaata tttgatccga ctagacaact ttattcaaac cttgtcaaat
    13081 gtagacagag tagagattct tccttatcat acgatgggaa aatacaagtg ggaaacactt
    13141 ggtttgaaat atccattaga agggatcgaa ccacctacaa aagaacgtgt cgaaaatgct
    13201 aaacgattgc ttcatacaga agagtataca aaatatttaa cgcgataggt cgcatcggaa
    13261 agaagataag tattgcttct ttccgttttt ttgctattat taaataggag aaatcacaaa
    13321 ggagcgaatg acatgtcaaa aattttagtt tttggtcacc aaaatccaga tacagatgca
    13381 atcggggcag ccattgcgtt ttcacacttg caaaatgaat taggtaaaga aacagaagca
    13441 gttgctctag gtacacctaa tgaagaaaca caatacgcat tagaccactt tcagctatct
    13501 gcaccacgag tagtagagtc agctaaagca gaaaatgcag atgtcatgct tgtggatcat
    13561 aatgaattcc aacaaagtat ttcagatatc agcgaagtaa atattttagc tgtagtagac
    13621 caccatcgta ttgcaaactt tgaaacagct aatccattgt actatcgtgc agaaccagtt
    13681 ggatgtacaa gtacgattat tttaaaacta tataaagaaa accaagtaac aattcctaaa
    13741 gaaatcgcag gaatcatgct ctcagctatc atttcagata cattgttgtt caaatcacca
    13801 acatgtacgc ctgaagatga agcagctgca aaagaacttg cagcaatcgc tgaagtcgat
    13861 ctaaacactt atggacttga aatgttgaaa gcaggaacaa atctaagtga taaatcagct
    13921 gcggttcttc ttgatttgga tgcaaaaagt ttcccaatgg gcagttccaa cgttcgtatc
    13981 gctcaagtca atacagtgga ccttaatgaa gtgatggatc gacaagcaga gctagaagca
    14041 gcaatggaag atgaaatgaa agcaaatggc tacgatctgt tcgtattagt tgtcacaaac
    14101 atcttagaca gtgattcaga attacttgtt gctggtaaag gaaaagaaaa agtagaagaa
    14161 gctttccaaa caactttgac caacaaccgt gctttgctta aaggtgtcgt ttcacgtaaa
    14221 aaacaagtcg tacctcaatt gacggctgta tttagctaat caaatggtag tatgaagcat
    14281 tcaaaatgaa tggataagcg attgatataa aaagaaacat agaacatact aaaggccgaa
    14341 gaaatggagg agaataacag tcaattatga ctcttgttct tcctcctttt tacgtaaaag
    14401 ccttttaagt aaaataaaac ggatagaaaa gagaacatat atgaactatt attcaaaaaa
    14461 taaggaaaac ttttatcaaa aactgaccga tgatccgctt ttttcttcat tgaccgatta
    14521 tctatatgaa catcgagaac aagaaacgat tctaagagaa ttgaaaaaag aattttcgca
    14581 aaataaattt tcccattttc ttgatttatt gatcgatgca ggattaatca agagggaaga
    14641 acgaagatat catttgaact ttccaatatt tgatcctaaa gattacttgc aacaagccac
    14701 ttcggctgct gaaaccatag ctgaacaatt gaagagactc tctgttgatg aacaaaaatt
    14761 agcgatggga gaagttattt gggcgtattg tttcgaagat gaacggaaag aagcgtattt
    14821 ttatggagta agaaacagcc gagagacaga attgctgagg acaactgcag gaaatgagaa
    14881 gtaccgtttt atcacacttt cctctataga acacttcccg cttactttgg ctaattactt
    14941 ttttgtacag aagaatcagc ttcctgtaac gaaggcattc aaagaattag ccgaacttat
    15001 tggagacgta aatgaatcgt acttttttga tcaaatagaa gttatcgttg acaggatacg
    15061 taagaataaa tataaaaatc gccggcctag tattttccat cagtctctac ttgtgacgaa
    15121 tactataaag gaagaagaat cattcacatt agaattacct attgtcgaaa aaaacaattt
    15181 tgagattgaa ttaccaacat tggatccttc attgacaatg gaggaaatgg cctttcttaa
    15241 acgacaaatc ttttctgagc tgagcaagaa atttataccg catgcatttt cttatatcaa
    15301 agaatatgga acagttttag tgagtaaaac ctaagagagc agtaagcaaa aattatactg
    15361 actcttgcag gaggagcctt tctcttcctt tatggttaaa agaattattt gagtattttg
    15421 cctatctacc acctattaga ttcactacat ggtctggaaa caaaggaatg caaaaaaatg
    15481 gtgagaaatg tggaatgaca aaggaagtag tgataagaaa agttagattt ttaaataatc
    15541 aatattatga ttcagtcaag tatggcattt tatgggaaga actagctgat tagattagga
    15601 agtccatttg ataatccaga atcactaaga aacgaatggc gagtcattaa taatttatcc
    15661 aatcttgggt tattctttta gattgaagtg tttaaaacta aaaaagcatt tatgaagtcg
    15721 taatagtcag gcttcaaaat gctttttatt ttgtttgttt tttctttgcc acataaatac
    15781 acctagactg acgatgaaga gcatatccaa cagatttcct gcgacttgga tcgtcgaagg
    15841 gttggtcagt ggcattaaag caaggacaaa aaaggaaaac aagctgtaaa taaaacaggt
    15901 gacaggaact aatcgaaaga agagcggaca tttcaattgg ctaaaaatga gtgaaaaaat
    15961 aaaataagta aaaatggata aaatcacgac taaaccattc atgataaaga agaaaagcgt
    16021 attgtgatta aacgaataaa aaagaattgc taaaaaagaa aacgttttaa atgcaatcaa
    16081 tacgcttgaa gcttcgttta acgtaccagg atgtcgatga aaaaaatagg caccgaaata
    16141 aacagaaaac agtaagccgc aaagagaaga caaaatcaaa aaaaacggat tttcttcggc
    16201 ttctgtgata tcagaatgat ccaaaagcaa ccagcctaat gcactagaag gcgcatgtga
    16261 ggtcttaagg tatgaataac atagaaaaaa taagatcgtc aaagttgcaa aaaaagagcc
    16321 taaatgtaaa aaattagtgg ttctacgttg aatttccata atatctccaa attaaattga
    16381 taagtatata aagtataata acaaattgat gagtatatgt cgatgttttt taatcaaaat
    16441 aataaataaa aactgtctaa catttaaaat ttaatttaga tattagacag tttttaagtt
    16501 tgtgagttat tttccttgtc gttttctcac ttttttagtc cagaaaccac ctgaaatata
    16561 ttttggctca taagaaatga taaaagcacg ctcttcgatt tctttgatca ggcgatacag
    16621 ttcacgttcg ctttttctag gagaaagtat ttcgagaact agccgctcac cttccagccc
    16681 cattgcagaa gtctgtgtca caccataacc gtgttctctc agtatacccg gcaaactttt
    16741 atcttctgcg ctatttgctg gcaaaatcgt tgtgaccatg atgtatccta atgccaattt
    16801 gtcttcaatc aaaattccga cactgatacc tactgcgtaa cctaacgcat agacaaataa
    16861 attcagtgga ttatctaaac gatctaaaac aagggataag ccgacgatat aaatcgtgat
    16921 ctcgaccata ctgacaagtg gagcaatcag tcgatagcct ttcattgtca acatgaaacg
    16981 taacgtgttc agagtgatat aagcaaaatt aatgaggaag atcatcccca acatttttgg
    17041 atcaatcatt tgtaaaactc ctttcattta tataacaaca atatcaaaaa aaatcgtaag
    17101 tgaagaaaaa ttgaaacttt atacatacaa aaaaatgata aaatgattat aatagaatta
    17161 taaagatagg ttaggtgatt aaaatgaaaa cggtcaatcg tgtgttttgt gccagccacg
    17221 tgctaagtct ccttctcagt atatacttag gtgtctattc gattcaacag ccaattgagg
    17281 tagagaacat tgtttttcag atgtcgctga cagatggttt aattttaagc gtttttttct
    17341 ttttgatact gtttattggt aatattttcg gtagcgttgc cagttttttg aatttttcta
    17401 tttatccact cctttcgcta gcattaggag tggtgggact ttgttctctg tgcttatttc
    17461 ccgagccatt cagtcctgca tttatattat ttggtacact gaacctgttc cagacaactg
    17521 ttggagcatg gttgctatgg cgatcaggaa atttaatgaa aataggtgag taacaattga
    17581 atccaattat attgaaacgt tctgtccatc atattccagt gttagaagtt gttctgaaag
    17641 aattaagaga ggaacgtatt cccgttgtca tctattatca cggatggcag acaagtaagg
    17701 agttagtttt gacgcaagga agaaaaattg cgcagcaggg cattcgtgtg atcctgccag
    17761 atgcgatgaa tcatggggag cgcaaacagc cggtttcttc tattccatcc tatacatttt
    17821 gggatagtat ctacggaaat ctgtttgaat ttgacacact tatcaagcat ttagaaaaaa
    17881 gaggtcttct acatgatcag cttgcagttg gcggggtttc gatgggggga atgacaacat
    17941 gcgccttgtt ggctaaacat cctcatatag tagcgggcgt gtgtttgatg ggttcccctg
    18001 cacctttgga atatggaaaa gaaatcgtaa ggcgcgcatc ggaatataat tatgtcgtac
    18061 caaaagacta ttttgatttg atttcatggg ttaagagcta tgatttgtca ttgcagccgg
    18121 aaaagttagc tggacgtcct ctgttctttt ggcatggaca agctgacgaa aaaatccctt
    18181 atatacaaac ggaacgattt gtagaaaaaa atcggcataa gtcttacgga aaagaaattg
    18241 tttttcgttc ctcaaaaaca cagcgacata tggtacaaat accactaatg gaagaagctt
    18301 ccactttttt agcaaaaaat ttgataaaaa agtataaata attgaaacgg aaaatcactc
    18361 atgacgatag aggattttcc gttttttatt ttgggctata ataaactctg ttaggaaaat
    18421 ttggtataat tgatagtaag aatgacaaca tgttagaaag gaagagagca tgcccacttt
    18481 agcagatgtt gcaaaacgtg ccaatgtttc aaaaatgacg gtctctcgag tcatcaatca
    18541 tccggaacag gtgactgacg aattgaaaga gttagttttc tcagcaatgg ctgaactgga
    18601 ttaccgtcca aatattgctg caaaagcact tgtcacgaat cggtcgcaga tcatcaaatt
    18661 atttatactg gaagaaatcg acacaactga gccctattac atgaatttgc tgatgggaat
    18721 cgctaaacgg atcggtaaag cgcattattc tctccaatta gttacaaatg atgccttcga
    18781 cgtcggttct tgtgatggat acatcatcac aggtgtcaga aaaaaagact tcgattggat
    18841 cgaccgtttg gaaaaaccag ttgtcttgtt tggggaaaat tctgaaggat atgattatgt
    18901 agacagcgat aatgaatatg gtacagcaaa agcaacgcaa tatgccttag aaagagatta
    18961 tcaaacgatt atttatatcg gtatcgaagt ggacgagcct tttgaaattt caagggaaac
    19021 tggttattta tctgtgatga aggaagttga tcttcctagt aaaatcttgc ggtttccaaa
    19081 tcattcgaca gaagtagaaa gatatatgac agaaaactgg gcagatttta cagataaaac
    19141 ttgttttgta tgtagttcag atcggctagc actaggagca gtaagaggga ttataaatgc
    19201 tggaggacac ttgcccgaag aatttggtgt gattggattt gatggggtat ttttagacca
    19261 aatcagttca cctaaattga caacgatcaa gcaagatatt atacgtatgg gtgaagtatg
    19321 tggagaaatg ttgttaaaaa aaatagaaga aaaaggggcg agtcaaggtt atcgtcgttt
    19381 ttttcctgaa ctagttatca gagagacaac gaattaagtc ttattactat atatatattt
    19441 atgaaattca tcgctatttt cttaaaataa tcagcgcatt gctactgaaa acaatgaatc
    19501 tgtgctatta ttgagaaaag ttccattttt gagaaggatg gtttgaatga aagaaatcag
    19561 acgaaaacat ttccgttttc ctgcgtacga tgatgagtta ggcgtaaaat taaccaacga
    19621 caagaagcga gtattatttg acggacaaga agatcttttg actgaacaga atcagtcccc
    19681 gtttgaacag atgaaagaat ttcatttcac gaacacgaac accgagaaaa tccgtcgcaa
    19741 gcgtcgtgca acaaatggat tgaagtcagc tccgcgtaag gaaaatttgg aaaagcataa
    19801 aggaaaatta ccggattata ccggccatta ccaatcagaa atcacatcga caggacgaaa
    19861 aaaacttttt ggtgattcct ctcgttctgt cagacaaagt gaaacaagga cagagtccaa
    19921 gcatactaca cgaaacgcat ctgttgacac gaaggtgcgg gagcgttctt attttgttcc
    19981 taaatatgta cccgcatcga ttatcccaga ccctagagaa agcaaaattt ctgaggatca
    20041 tttaatcgaa tcgatgaaaa aaacggatga ctcttatctg ttgttcgata cagaaccgac
    20101 gccgtatcaa gaaaaaagaa atggtgagcc gtctgtacga acattcaatc gaacaaaaac
    20161 gttagaggaa acaaagcagt cagaagaaaa aaaatcgaaa aaaagccatg gtatcttaga
    20221 acgctcatta caaggattga tcgatgatca aggaaactct ttgggagaaa atagctattt
    20281 taaataagtg atatacaaat ttatattcgg ctacagttgg aaaggaaacg ctgcggcgtt
    20341 tccttatttt atactctatc cgaaagttta tatcgtatcc tcaaattttt ttgagtttaa
    20401 gcgaattttt tctcccaata agtaagaaaa taatggcaaa ataaaaaaac aaactatttt
    20461 cgcagatcgt ttgcaaaaat agtttatttt tttataaaga agattttact gaataatatc
    20521 attttagttt acataatgat atttctgtaa attaaataaa gtagtgaaaa ataagaatca
    20581 gtgctctaac tgttcaagag gatcaagtgg ttcaaatgtt tctgtagtct gttttgcttc
    20641 caattggggc aaaacagatc caatttccag atacttcact ttattcaatg tataagatag
    20701 aatagaacag ctaagtaatg tatacagaaa atgtgtgaga tccaaataaa gcaaggagac
    20761 aactaaaata ccaaaagtaa tcaagaaaag acttttgcca atcttaatat gaaaatattt
    20821 ttcaatggct tgataaatga tatctgttcc gcctgtgctt ccgccgaatc gaaagacgag
    20881 accgcaacca atgccagaaa gaatacctgt catcaaacta ttgatcagta gactatctac
    20941 agcaaaatgt atatgaaggc tctcccataa atgtaaaaag aaaactagcg caaatgttcc
    21001 gacgatcgtc cggagaaaag cgtgttttcc aaaaagaaac aatgagataa gcaataaagg
    21061 taaattaaaa agcagtgaag tgacagaagg agcgaatcca aaaagattat gcaaaagcaa
    21121 agcaatacca gtaaccccac catctgccag cttagatgga atattgattc ctgtcacagc
    21181 taatccgtag attcctgcgc ctaaaatgat tccgcacaat tctgtaaata aatttaattt
    21241 tttcatttct agcctctttt cttttgaaaa ttttcagcaa cttctttatt atactgactt
    21301 atactcttac ttcaagagga aaatgaaaaa aaattatttt tggctgtttc tttttattta
    21361 tcaaataagg agtggaaaaa tgcgagcagc agacttattg acaattctta caaaatcacc
    21421 caaaaaaaca gagtatcaag gagttttttt ggctcaagaa caaaaactgg tgcctgtgac
    21481 aatggtccag ataaataaag caaatcaatt tatcttttta tttgaacacg gcaaagcacc
    21541 acttgctatg aaagacatct ttcttttttt gatgaagaac cgtgagaaag ctgtttatta
    21601 tcagtcaaaa gaagaactca ttcctcttta tggagtgaaa gagatagaaa ataaagtggt
    21661 gatataagta aaaataagaa aacaagacgt ttatgatgtc aaaacaacca ttttttacat
    21721 ttttggcaaa aaagtgtcat gatacagtat aatattcgtt gaacaggcca ataaaggtgt
    21781 tctcccccac gagatttcta ctttattggc tgtttctttt ta
//
LOCUS       DAYNVV010000045        21614 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.045, whole genome shotgun sequence.
ACCESSION   DAYNVV010000045 DAYNVV010000000
VERSION     DAYNVV010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21614
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.045"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..504)
                     /locus_tag="ACGXWR_001933"
     CDS             complement(<1..504)
                     /locus_tag="ACGXWR_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803486.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQ"
     gene            complement(728..1612)
                     /locus_tag="ACGXWR_001934"
     CDS             complement(728..1612)
                     /locus_tag="ACGXWR_001934"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFK0803487.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(1711..2148)
                     /locus_tag="ACGXWR_001935"
     CDS             complement(1711..2148)
                     /locus_tag="ACGXWR_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803488.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            complement(2365..3276)
                     /locus_tag="ACGXWR_001936"
     CDS             complement(2365..3276)
                     /locus_tag="ACGXWR_001936"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFK0803489.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(3733..4161)
                     /locus_tag="ACGXWR_001937"
     CDS             complement(3733..4161)
                     /locus_tag="ACGXWR_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803490.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(4189..4827)
                     /locus_tag="ACGXWR_001938"
     CDS             complement(4189..4827)
                     /locus_tag="ACGXWR_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0803491.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(4831..6867)
                     /locus_tag="ACGXWR_001939"
     CDS             complement(4831..6867)
                     /locus_tag="ACGXWR_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HFK0803492.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERVISLF
                     TDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLL
                     MNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYV
                     FLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFS
                     SSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSI
                     LVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRH
                     TDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSM
                     YLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLS
                     RSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNL
                     IKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            6993..7658
                     /locus_tag="ACGXWR_001940"
     CDS             6993..7658
                     /locus_tag="ACGXWR_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0803493.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDF
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            complement(9593..12742)
                     /locus_tag="ACGXWR_001941"
     CDS             complement(9593..12742)
                     /locus_tag="ACGXWR_001941"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009035 - type I site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HFK0803494.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDSQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDGVYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNEKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSSEQINRMIDQMEPVKKESYLDPAVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQLIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLAIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PDKTKGLIVTFRKPATMEKNVEDATKLYSKAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSPTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYLPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(12755..13954)
                     /locus_tag="ACGXWR_001942"
     CDS             complement(12755..13954)
                     /locus_tag="ACGXWR_001942"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFK0803495.1"
                     /translation="MSNDTRPEIRFPGFTEDWEERKLIDLVVRLNKSTNSSRLPKVEF
                     EDIVAGEGRLNKDVSQKFDNRKGIEFLPNDILYGKLRPYLKNWLKATFTGVAIGDFWV
                     FRAKKSDSDFIYSLIQADRYQKAANDTSGTKMPRSDWKKVSDTVFYIPNDLKEQQKIG
                     IFFKKLDDTIALHQRKLDLLKETKKGFLQKMFPENGAKVPEIRFPGFTEDWEERKLGE
                     LGKTQSGIGFPDAEQGGSEGTPFFKVSDMNNIGNEYEMRNANHYVSNEQIERKKWKPI
                     KDVPAIIFAKVGAAIMLNRKRLVTSPFLIDNNTMAYLFNNTWDIYFGKILFETINLPR
                     YSQVGALPSYNSSDIENISVKVPVKDEQQKIGTFFKQLDDTIALHQRKLDLLKETKKS
                     FLQKMFV"
     gene            complement(13944..15539)
                     /locus_tag="ACGXWR_001943"
     CDS             complement(13944..15539)
                     /locus_tag="ACGXWR_001943"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HFK0803496.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAIAPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVDVLEHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEMWLQGALEVFKHEQ"
     gene            complement(16048..16830)
                     /locus_tag="ACGXWR_001944"
                     /pseudo
     CDS             complement(16048..16830)
                     /locus_tag="ACGXWR_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(16895..17731)
                     /locus_tag="ACGXWR_001945"
     CDS             complement(16895..17731)
                     /locus_tag="ACGXWR_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFK0803497.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(17749..19158)
                     /locus_tag="ACGXWR_001946"
     CDS             complement(17749..19158)
                     /locus_tag="ACGXWR_001946"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFK0803498.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(19172..20995)
                     /locus_tag="ACGXWR_001947"
     CDS             complement(19172..20995)
                     /locus_tag="ACGXWR_001947"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFK0803499.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
BASE COUNT         6550 a         4352 c         3421 g         7291 t
ORIGIN      
        1 ctggaactcg atcgactgag gtatctcatt gatataaata tggtgtgtgc cgaaattgtg
       61 agcgaatcca ccaaaatcaa taacgatatc tcgtttgatc tctaattccc tgtctaaagt
      121 caaaggctga atcagtcgga tcttagttac tgattcgtct gcgagaagct gcgccagttc
      181 ttctgttgtg gcagcttcgc tgtacccatc cgctgaaaca gctcttgcca gtgccgcttc
      241 actgctatca gacgtttgtt cagctacttc tgaggtctca cttgtcttat tttcttcttg
      301 ccttttatta gtagaagcct cactttgaga ttctgtagtt tcagaagtaa tcgattcttc
      361 tgaaaaagta gtcttgtcaa aactttgatt ctctgattgc gttgattcgt ttgttttctc
      421 tacatcggca aaaacggatg tcaccatcaa gagagggaag acaaacaaaa tcgacgcaat
      481 cagctttttt acacattgat tcattctcca ccatcctctc tgacgttttg acaattttat
      541 tttatcgttt taatctattt ccaattgtac tttcatattt aaaatatgta tttttatgga
      601 aaaatttttc tattaggtgt aaatttcttt tttgtacaaa aaaaaggctg tgacaaaagt
      661 cttgtcacag tcccttatcc cgaacaagcg gtgttctccc gccaactcct cggtcacaac
      721 ctccatttta acaataaacc tgtaaatgtg agggcaatac tttgattgtc acaggtaatt
      781 tatccccttc atctccatca acattcgtcg tcaattcttc ctcatcagct aatgacacaa
      841 ctaattgctc acaagtaagg taggctagat ttttcgtaga ttcatctact ccttttaata
      901 ggtctggcaa tgttttaagc gtatcgatca aagaagaatc ttttaaataa accaaatgga
      961 gcttaccatc atccactttt gcatttggaa gtaatgtttc aaaaccgccg actgagttag
     1021 ttagtcctat cagcaaggta ctgctctcaa tttcttcctt ctttccatca acttctacgt
     1081 gaaacgagta ggattgtgtg gaagctaact gtttgattcc tgacatgaaa taagctagtt
     1141 ttccaaattt cgtcttcttc tccgcatcta catcattgat tgattcaggg atagagccaa
     1201 ttgcgacgac attcataaaa tagtcgtcat ttatttttcc aatatccaat ggcttgactg
     1261 attcaatcga aaaatgattg atcgcttcct caggttctag cggtatccct aatgctcgag
     1321 ccaagtcatt caccgtaccc aatgggaaaa atccgaaatt tggccgatgt tcttgttcag
     1381 cgattccact gattccttcg ttgactgttc catctccgcc catgacaaac acactatgat
     1441 acccttccgt agccgcttcg cgagtaaagt tttttgcatc ccctgctttt tttgtatgca
     1501 agacgaccac ttcatcaaac accgattcca attttgctat cgctaattgc tcaaattcct
     1561 ttgcttgttc accgcctgaa ctggggttta ccactaataa aacttttttc atcactttct
     1621 ttcccttctg actgattgat ttctttaata taacgatagc ataaagaaaa aaattaggct
     1681 gtgatgaagt actgttcatg aaacattcat ttattttttg acaagataaa acatccatac
     1741 tatgaaactg aggaaaatta aaacaatgat ataggaaata aaagaaaatg ataggcattg
     1801 tatacctaat aaagtaaaaa tcttaggtgg cagataaaaa cacaaaaata gcaagagaat
     1861 gtaatagcgt ttcttccact ttttgttatc agaccttata gcgatcagag gaataccaaa
     1921 tgcataactg aaaaactctt gatgtactgt taatatgtca cggccttgaa taataaatgc
     1981 gacaatcccc gctataatta gtgtgcctaa caccaaaacg gaaaattgat gaatatattt
     2041 tatatacaaa tgatccattg tacttcctgc ctttttattt gtgagaaaaa caaatccgta
     2101 tacgtgaata acttctagaa ataaaagaaa tttgcaaaac cactccattt atctacttct
     2161 acgtgcattt tttgatattg ttttctttat ttaagattat acagaaaaat atctagggtc
     2221 gctggattct aagtaaaaaa aatttttaaa ataaaaagaa ctaaatcaag tagtaattaa
     2281 actactgttg atttagttct aataaaaaga tttagatgaa cagttttatt gatttaaata
     2341 gttcatattt tttatttata ccgcttattt actacttgct gtactagaat ctgaagtgaa
     2401 tgtactcaaa acattttcaa agtctttgtc tttgattttt acattagcgt ctttcaatac
     2461 ttcgccaatt actttattct ggaaggtact gtcacttaat tttgtgtctg ttgcaatttc
     2521 tttcaattct tttttgtatt tatccatgtc gttgcctttg ttttggtttt tcaccatttt
     2581 aaccacataa tattccgtag tataagttga agcattggta gaagtgatca catcagaaac
     2641 ttgaccatct ttcaacttaa aggctgcttc tttgacttct gccggaaccg ttgtagtagt
     2701 ggaatcaaat ttcacttttc cgccatcttc ttttgtcgta gtatcagttg acttgtcttt
     2761 ggctaattta gagaaatcgt ctcccttatc agcagctttc ttcacatctt ttgcatcatc
     2821 ttcacttgct acttggataa tttgagcttc cacttctgga tggaaagatt cccaagccgt
     2881 ttttaaatct tcatcggtca atttgatatg tttctttaga ccttcttgaa aggctagact
     2941 ttgtttgata ctgtctttga atgtttgttc tgtgtaacct gcagatttca attgtgaatc
     3001 aaatgaatca cccaattgtt tctttgtttg atcatattga gaatcgattt ctttggttga
     3061 tacgtcatct ccatatttat cttcaaatac ttgataaacg atcaactgtt gcacagcgga
     3121 atctgctcct tgcatttttt tcaagctatc cattacttct tgttcgctga ttgtaccgcc
     3181 tttataacta acggctgttt tttcaccggc attcgtacag cctgacaata agccagtgcc
     3241 tagtacgatg gcaagtgcta aaaatctttt tttcatttat caattctcct acttttcgtt
     3301 ttttgcgaat tgctaaaaac aaaggtgttc aagatgaaaa tcatcaagaa cacctttact
     3361 aatctgctcg atacgtcctg aatagatata aggctacaca atccagaaag ttcgctcagc
     3421 agaataaatg tcaagtagca catcacacct taatatacta cttcttttgt taccgttttt
     3481 caagtctatc ttgcgttccg tatttaacgt aactaattct tagaacaaat gttatcgatt
     3541 ttgtttttct tcttccgctg ctgggatatt caaatcagac acttttatgt tcgattttcc
     3601 agacattttt ttgttgtttt tattatgata tatttttata caactaaaaa tgaatatatt
     3661 aaaactacca aaaataactt ttaacgctgt ttcattatat gttttttcta ttttatataa
     3721 acttttggat acttaatacc aaccggttgg attgtaccaa catgagaatg tgtcagttct
     3781 atttcctgtc gcacttgcat aggcccatac tccttttgtt gcatttgctg atcgaataga
     3841 gtttccaact ttcgcttttg caccgtgacg attatagaca cgactatagt ggttagaatg
     3901 acctgttttt ctcgtacaag ttgtatcact ataataaacc catcttccag agctatgatt
     3961 aattgctgtt ctagaaattt cccggtctac tggtaaattt gacttaataa tattaccttt
     4021 agcatcaaaa tgaatctctc ctggctttaa agatttgtaa tagatttcac cgtgaactga
     4081 atttgcttcc acttcagatg acatagcgtt tcctccaaca aaacctatcc ctagtgcaca
     4141 aataataact gcttttttca taaaacgaca tcctttcctt tttgattttt aaagcatgat
     4201 cttcttgttt cctattttgg tcagatatgg atcatgcgtg actacgataa ctaacgtacc
     4261 ttgggaagct tgttgcgata agatttcaac tactttatcc ttatttcttt tatccaatga
     4321 cccagtcggt tcatcggcta aaatgatttt gctattcttc aataagactc tcgcacaggc
     4381 gattctttgc ttctcaccac cagataatgt gtagataggc gtacttagct tcttgtttat
     4441 atttactttt ttcaatgcct catactttgc tgttcgctta tctgaaacat ttaaattcga
     4501 aaacttcaat ccaatatcta aattaaaatc gattgtttca tattcaatca acccaaaatc
     4561 ttgaaaaaga aaagatatgg tatttctttt tatcaagcgc ttctctctcc cagttaattg
     4621 tttcgtctct tgatcgaaca aatagaattg tcctgaactg aactgatcat tcaatcctaa
     4681 tatattcaat aacgtacttt tacctgctcc actttctcca acaacagtca caagatcccc
     4741 agcatccgca gtgaaacgat ccaaatgaag aatcgttttg tttcgaatga tttttttcgc
     4801 accttttatc actatcaacg gctccaattg ttaacctcca ttcatcagca ataactgact
     4861 tttcttttct gtagacaaaa taaaaacaac tgaaagaata aaatcaatga agctaaagaa
     4921 aaaaatatta aaaagatatt taggctctct ttctataaga aaaaggaaga ttacacttgt
     4981 cgttccccat ttgatgaggt tcatcatgaa gaaatcttta tacgtttcaa agagcgaata
     5041 accacttgaa cgaaagatag cgattttccg acaattgtag acaaaatata tgcataacat
     5101 gacatagctc aacaagaaga aagaaaagaa agtgagtaaa aatatctgta tcaagtaatg
     5161 aaatgatctg cttaacactt tgacagctat ctcttcagtc tgagtatacg gaaatgataa
     5221 ctgcaagtta tcacgtaact gactttcttc aatcagctca aataaccttt ctttcgacaa
     5281 agagcctatc ttgatcttta acggtggata gatttctccg ctgagaatat ttctttccaa
     5341 atacatactg tttttcaatg tcagtatttc aacaaccgga taatgttcga tccaggggat
     5401 agaaggaata aatgtataaa tgggttgatt gttttttata aatagaaatt tcggttcttt
     5461 ttcactgatt tcttgataat attctgttat ttgcgccagg tcatttttta aatctgtatg
     5521 tctatatcgt tcagggatca atataacagg gtgcgtttct ttttcggtta tttggatcaa
     5581 ccttccagag acatcaatca aaggaaattt cttaagataa ttcagattta tttttatccc
     5641 tctgccaaac tgttcatttt cttcattcaa gtaatctgat acattgacta atatacttcc
     5701 gtttttattc aaagtttcat ataattcctg atctgctgct gatgcaaaac gattggaata
     5761 aataaaatcc acgtggtttt tcccgatggt tactggataa aatacatgat agtcctcacc
     5821 agcgatttct tttggtggtt catgggaaac agctaactgt gaagaagaaa aaacgatagt
     5881 tgctaattcg acattggcaa cggtcaaaag aagagaaaac aacaatccaa atgtaaaaag
     5941 aatgtattgg atatagttga acgcttctct taacgaagcg attttttcaa ctaataaaag
     6001 agaaatcaaa gagataccat atattccgct gaacaagaaa acgtacatct ggaacaaata
     6061 aagaaattgc tccttataat acataaaaat aaaaccacca atgattcctg caattatgaa
     6121 tgtaataatg attttctttt tccccaataa acaccacaat acttgatgta atgaaaagtc
     6181 attattcaac aataaactga tttctttatt catcaataag aaaaaggatg ataacaaaag
     6241 gaataaaaga atcaatccaa tagttaaata cactcgataa ttatatacgt ctgtatttga
     6301 aataaccgaa tacgaatagc tattttcaaa gtcttcaaaa atattagtgg cataatcagt
     6361 gtgaaatgct tgattgaatc gatcagtgaa tagtgaaatg acccgttcat aggcttcttt
     6421 ttctctcgtc atcaagaaaa attcaccttc aaaatctttt attttgatcg attcttcaat
     6481 ggacgttacg cgaaaggagg tattagaata gggtaccttc tcgtgagaag atttgacatc
     6541 cccttgataa tacaatgtca tttcaagctt tggctgtatc ttgaagttcc aagatgtatc
     6601 tacttcattg gattcattta ctgttttttt catataagaa agctcagttt ctgatgagac
     6661 attttcaaat accatgatta gctgctcata ttcttcttgc ccaataaaat gttgtggcaa
     6721 tcgaatcgga gtataagtat ctgtttgatg gaaaaattca tttgtccgat agagtacctg
     6781 tttatttata ctaaccaagg caaaaccact catgataccg gtcactatga ttgtgagtaa
     6841 aactgtgaac ttttttttga ttatcaccac tctcccttac ttaaatgatt ctttgataaa
     6901 atcataccgt ttttcatcaa aaaaacgtat ctatcaagtg tataggtcat gtagaataaa
     6961 tctatatact gtagaatcga aaggagaaga agatgaacac cggagaaaaa atacgaactt
     7021 accgcagaaa ttgtaagctt acgcaaaaag aattaggcga aaaaattggt gtttccgata
     7081 aaacgatttc tagttgggaa aattctcgta caatgccaga ctttgaaatg ctgtcacttt
     7141 tacatcatac tttaggtctg ccgattgatt ttccttctat tgaatcagct accgaatcaa
     7201 tagaaccaac attgccagat gaacctcttg ttaacaagaa atcttattca tcaaaacaac
     7261 ccttctcact caaaaagaca ctatctttct ttctgctcgt cttttgtttg gtctatcttt
     7321 ttcttatcaa ttatcaatac aaaaatgaaa cgatcgatcg attcaatcct tttttgaaac
     7381 cacaaatcgg ctataccaca ctccctgtag gatacgtgga caattccatc gaacgttggg
     7441 tatgtaatga tatctttggc catggtacat ggctgtcttt tcacgctgga gaggtagaaa
     7501 aagagaaaaa ccatgctgta atcaaacaca aaggaaaaca cgtcatgaac gttcgcctgc
     7561 tcacttggga agccattccc tcagattacc aagaaatcct cagccaagac tatgacgacg
     7621 ccttaaaaag aagccctcag gagccagata ggcattaagt aggagatgaa cgtagagata
     7681 gaaaaaatca atgcacatga tcttatccaa aaaacagggg tacaaattaa ttgaaaaagc
     7741 cttgagatga aagttcctaa ataaaaaagt tcagaatgat aggtatttct ggcttatagt
     7801 ataatattta cgccacagcc tcccaatgat tctttttgga atcataatca aggatggaca
     7861 ttcacaaaaa tattttgctc attcgatccg aatagattaa cgaccaatct agtaagtaat
     7921 atagattggt acgtagtcaa gctgcacata atttagatca attttagttc ttttttatat
     7981 ttctatgatc tgctcattta cttttatatg atggcttaca gtaacataaa taaatatgat
     8041 aatcgctggt agtttatcca agagtactca ataaaataca aaatggattg ttcaagcgcc
     8101 tatcataatg ataaaatgaa acaaataaac gatacaagga ggaagagact ttgagtaatg
     8161 gcagaacaat tttttcattg taaaaattgt tcagttgtta atctatggga tttcggtagc
     8221 atgggcattt ttttatagag gaatcacacc aacctggccg ttttatctct tgttagtggg
     8281 aatattagta ggaaattttg cccctcttca ctatcgtacg aacttttttc caactgattc
     8341 tggccttttt cttaaaacaa agacgcgaaa attagaaaac attattgaaa tgacaattac
     8401 ctgtataatc attttcttag ttatattcct aaacgtcttc taataagaat ctcttaaaat
     8461 tagcttgtta cagttagtta cctagtttat ataacacagt tatcttatct tccttatcaa
     8521 catcttttgc caactctttg tcttaaattc gaaacatata agcagagcta cgaacaccaa
     8581 gactgtttcg gctctgtttt ttgcatcaaa ttcactctta tatagctgat aatctcggct
     8641 ctttaaaaga aattattttc gcttcatttt attataaaaa ggctaggaac cttgatgtta
     8701 tcaggttcct agcctttatt taagtattac cccacagacc cttccatata gatttttaaa
     8761 ttacacacta gtttaaacta aaacaaacaa ggaaaaactt accatttaat caaaaaatta
     8821 gctcatatga atatattaga atgtaaatta gactggtcaa aatctggtca aaaaagagga
     8881 cgaatacagg tagtcctctt ttttgttatt ttgatattct aaatcatttt ttattggatt
     8941 attcccttgt tcgatataga cccaaattga tctatcaata attatcaaac tgagtcatat
     9001 agagacaaaa atttcaaaaa tgacctgtta aatggtcatc gaatatcatt taaaatcaat
     9061 acgacggagt cagacacgga gtcaaaacaa gcccgctgag agtaaaaaat atacagtccc
     9121 ataggtaaag tgccacagga ctgtatattt ttttatttga gattacctga aatgattcca
     9181 tttaattttt atctcatttt ttcctactag ttagtatcaa atactctcct attttctcaa
     9241 taaactattt tgggttacat ggtatctgaa acagctaaaa ccttgtcatt atagcaaaaa
     9301 atcactttat ctccgtttca tttcagatac atttcactta agcggattcc aaaaaaacaa
     9361 aagaaaaagg aacccctagt tagcctatgc tttttattgg ttcctctcaa aacacggtca
     9421 tataacaacg gggtggggta aatgaatgaa aaaggtggag gaaacattat tcaatagctg
     9481 tcttaaatac ttcgttataa aatgtgaaca aataaaagac atctatccct attttctaca
     9541 cttccacttg actaccatct ttgaatcgta caattttctt aactcttctc gtttacctca
     9601 attcattctc aagtggaatc aactcatcat ctaacatttt acgccatgct cgcttcattt
     9661 cttgtgggta tttaaatggc ttcgcttctg gatgtttggc tttatatcct tcgtaatcct
     9721 tactgttgat aattgctttc atattaggaa ttggatcttc acctggtaga tattgcagat
     9781 tagaagcatg taattctttc tcagaaacaa accactcatt ggaaaagaca tgaatcaaat
     9841 catcactcgc ttgtgtaaaa tagcgacgtt taatgacaaa gatatcttca ttactatcta
     9901 aagtccccac atcaaatgca tttaaaattt gtcggtaaac ttctttgact ccttctgttt
     9961 tattcaattt agccaaagct ttttcaattt cttctcgtgc atctgaacta ttcgcagcat
    10021 aagttcctag taattgatca atataagttg aatcaatatc atacaactta gtggtatttt
    10081 cactataaaa ttcgatcgtt gaaaaatctt ctccttcttt ttctggttct tcctctatta
    10141 atgaaccctt cacggtctcg tacacgccaa tttgttcttc caaaagttga atttgattgt
    10201 tcaaagttgg agatttcacc atgtcatcat tgtaatcgtc ataagtcact aacgattcat
    10261 aagcacgatt caattcttga aatgctttga cgtactcgat acggatttca agtggcgtat
    10321 gttcatcaat ggattccatg gatgaaacct cttttaactt accatatgct tgtttgaatc
    10381 tttttttgga ttcctgataa cttggataaa tcaaacctga ttcttctttt gcttttgaat
    10441 acagttttgt cgcatcctcg acattcttct ccattgtcgc tggcttacga aacgtcacaa
    10501 tcaatccttt tgtcttatca ggatacgtac gattcgtacg tgaaaaagct tggatcaatc
    10561 ctgcatactc tagattacga tccacaaata gggtttgaat cgtaggggcg tcaaaacctg
    10621 ttaatagacg atccactaca atcgctaaat cgatttgttt cccaaattgt ttgaattccg
    10681 ctctttttcg tgccaaacga ttattgatgt ctccgttata acgctcaatg tctgctaatg
    10741 accaggaagt atcataatac tgattatatt cctcaataat tttttgcatt tcttcttgtt
    10801 gggcacttga atctcggcta ttttcttcta atgaataggt aatagcgatt cgtggaaaat
    10861 caggatcctc catcgttcgt ccttcacgaa tgagctgatt gggaaactct tttgttaacc
    10921 aatcaggctc tttcgtcatc tctttgatgg cccgataata ctttttggcc atgtcaatgg
    10981 aactcgtggt taagattgca gatttcgttg gcctgccatt tcgaaaatca aattttgtat
    11041 aggcattatc tggacggaac attttatgaa tgactttttg gatatgttca tctgcttcaa
    11101 aaacagctgg gtccaaataa ctttcttttt tgacaggttc catttgatca atcatacgat
    11161 tgatctgttc tgatgaatac tctgcatatg tttctacttc ttttaatttc cgatagattt
    11221 tattctctag tgaagtcggc tccacggtgt tttcatgctc tacttgaaat cctaagacag
    11281 agccatcttc tagcgcattc ttaatggtat aggtatgcaa gacctctcca tactgatcat
    11341 gggttgtacg tgccaattgc cctttggctt gtttccgatt ctcaggaaaa atcggtgtac
    11401 ctgtaaagcc aaaccaagtg gatttcggaa acattttttt gatttcttcc atattttcag
    11461 cacttaacgc tcgatgacac tcatctacta caaacacgat atgttggccc attaattttt
    11521 ggaagcgatt ggttcctttt ttctcttctt gtttctttgc atatttcaac gccgcatcta
    11581 gtttttgacg ggttgtaatg attacaacat ttgcattggc atctgccaac agggtttcac
    11641 ttaattcttt ggcacttccc gttccaacga tcaagctatt cgctttggcg ttcccggaag
    11701 aaatcccagt attaaattcc gaagcaaatt ttgtaaactc tgtggtggtt tgattatcta
    11761 aatctttgcg gtccactaac atgatcgttc gatcgatccc cgattttcgt gctaaaagct
    11821 tagtagatac aaaactagtc aacgtctttc ctgaaccagt cgcatgccac acataccctg
    11881 attgatgttt atttgcggca ataaacaagg cttgaatcgc atgtacttga taaggatgta
    11941 acaccatgag ggttttatta tcttgatctt cactgacgat tgtataatcc gcaatcaaac
    12001 gatgagcatc cgggatattt aacacttgtt tacaaaactc atataagttt tctacttttt
    12061 cattgtcttt cgttcgccaa ctaaataaaa acttagggtg caagtctttc ggtaaggcat
    12121 ttgcaaaata ccgagtggtt tgttcattgg aaaccacaaa caactgtaag gtcgaaaaga
    12181 tattgttccg aaacatacct tcttctgcat attttttgat ttggttaaat gcctgataaa
    12241 caccatcttt tgcagttact tgtttcagct cgatttggac aatcggtaat ccattgatta
    12301 ataaggtgac gtcaaaacgt cgatcccgtg cttctatgtt acttccacgt tttgcaattt
    12361 gatggaccac ttcataagta gagattcctc caccaatgtc ttgattggaa taaaggataa
    12421 gtgagacaga acccaattgc gaatcttccc gttcaatcgt gatccgagcc atcccatttt
    12481 caccttttaa ccatttcgca gcatcaaatg gggttttcgt tcgcagcagt aattccgttt
    12541 tgatcgtttc aaattcttta tcggtcaaag gaaaatcatt cagttctgct tgattatttg
    12601 agataatttt ttggcgtaaa ttgacccaaa ggtcttcttc tgattttaga tccggacgat
    12661 acgtccactg attatgccct tctccaagta cacgaatcaa ctgttcttcg acttctgctt
    12721 cctcacggtg actaattttc attcttcttc cctcctagac aaacatcttt tgtaagaagc
    12781 tttttttcgt ttcttttagt aaatctaact tacgttgatg aagagcgatc gtatcatcta
    12841 gctgtttgaa gaaagtaccg attttttgtt gttcatcctt tacaggaacc ttaacactga
    12901 tattctcaat atcagaactg ttataagaag gcaatgcccc tacttgggag tatcttggca
    12961 aatttatagt ttcaaacaat attttaccaa aatagatatc ccaagtatta ttaaataaat
    13021 aagccatggt attgttatct attaagaaag ggcttgtgac caaacgtttt ctattaagca
    13081 ttattgctgc gccaacttta gcaaatataa tcgctggcac atcttttatt ggcttccatt
    13141 ttttacgctc aatttgctca ttagatacat aatgatttgc atttctcatt tcatactcat
    13201 taccaatgtt attcatgtcg gaaactttaa aaaatggagt accttcagaa ccaccttgct
    13261 cggcatcagg aaatccaatt cccgattgag ttttacctaa ttctcccaac ttacgctctt
    13321 cccaatcttc cgtaaaacca ggaaaccgga tttctggcac ttttgctccg ttttcaggga
    13381 acattttttg taagaatcct tttttcgttt ccttcagcaa atctaactta cgttgatgaa
    13441 gagcgatagt gtcgtcgagt tttttgaaga atatgccgat tttttgttgt tcttttaaat
    13501 cattgggaat atagaatact gtatctgaaa cttttttcca gtctgaacga ggcatttttg
    13561 ttccagatgt atcatttgca gccttttgat atctatcagc ttgaataaga gaataaataa
    13621 agtccgagtc gctcttctta gctctaaaaa cccagaaatc cccaatcgct acgcctgtaa
    13681 aagttgcctt gagccaattt tttaaatatg gacgtaactt tccatataga atatcatttg
    13741 gtaaaaattc aatccctttt ctattatcaa atttctggct cacatcttta ttcagtctac
    13801 cttctcctgc cacgatatct tcaaattcaa cttttggaag tctactggag tttgtacttt
    13861 tattaagtct aacaactaaa tcaattaact tacgctcttc ccaatcttcc gtaaatcctg
    13921 ggaaacggat ttctggtcgt gtatcattgc tcatgtttga acacctccag cgcaccttgt
    13981 aaccacattt cgttttcagg tgttgtttgc agggaagaga tagcttctaa aagttctttt
    14041 tctagcactt gctgttcttg tcgtatcttc ttgatgtcat ttccgacatg aaccatatca
    14101 attggttctt cttcttcgaa agtatctaca tagcgtggga tatttaagtt atagtcattt
    14161 tctttgattt catcaaaggt tgccaaatga gcgtatttct cgacatcttt tctttcagcg
    14221 taggtttcga ggattttttg aatgttttct tccgatagtt tattttgatt tttcccttta
    14281 acaaattcac gactagcatc aatgaataat acatctcgag tttgacgatt cttcttcaac
    14341 acaatcaccg tcgttggaat cgatgtccca aagaacaagt tcgcaggcat accgatcaca
    14401 gcataaatac tgccatcttc tagtaatttt tgacggatga ccccttctgc agcgccacgg
    14461 aataaaactc cgtgtggtaa gacgatggcc atggtacctg tttccttcaa atgatagaac
    14521 ccatgaagaa gaaacgcaaa atctgctttg gattttggcg ctaatttccc ataacgatta
    14581 aaccgagaat catctaagaa agtcgtatct gctgaccaat tagccgaata aggtgggttc
    14641 attactactg catcaaatgt gtaaggttca tctgttggcc agtccttatt caacgtatcc
    14701 ccattgcgga gattcatttc ttcggcgtcg acaccatgta aaatcaagtt catttttgct
    14761 agattgtatg tcgttgtatt tagttcttgc ccatgatatt taacgttatc tgggtgtgtt
    14821 aagtagttac gtacgtttaa catcaatgaa cctgaaccca tcgttggatc aaaaacacta
    14881 aagaatcgtc gttccttttg atcgagcgtt acgatttgcg ccatcatatc agaaaccata
    14941 tgaggtgtgt aaaattctcc ggctttcttc cctgcttctg aagcaaattg actgatcaga
    15001 aactcatacg catccccgat cacgtcccca tcgtgttcta aaacatctac atcattcaat
    15061 ttcttgatga cttcggtaat cgtcacattt cgttgttgct catctgttcc tagttttttt
    15121 gattggagat ccacatcatc aaataaccca ttaaattgat tgtaggtaga tgccaattgc
    15181 acaaaggctt tgtttagatc gttcaattgg aacgttgctt gttttgcttg atccgctaag
    15241 acgttgaaaa gatactctgg tgcaattgca tatcccaaaa tatcaacgat tgtggcaatc
    15301 agatcttctt ttgattcttc atctgaaagt aattcacgat acaacattgt ttgtttgctt
    15361 actgtgtcat attcctctaa ggattcatct gctaaaagaa ccacttgttc caacaatcga
    15421 tcggataaat atttatagaa aatcagtccc aataaataat ttttatattc tgacgcatcc
    15481 attttactac ggagattatc tgccgcacta aataattttt gatttaattc tgcacccaaa
    15541 aagatacact cctatctctt atttaaagtt gctatatacc ctcttatttt agcatacccc
    15601 cttttataaa aagcaaaaaa aaaagaaaga aacttattct tgctaataaa ctacgcgaaa
    15661 ggagtctaac gttgtttgat ataacttaga ctgatcgtta acttattttt tatatttcta
    15721 catagttatc tttagaacca tttcagatac atatgaaaca attacatatg attttttcat
    15781 aaaaaaacag tactgtctag tagtataaaa tatacaaatt tcttaaaaat tttttcacta
    15841 aaatcactac ctgaaacagt ctaaaacact tatatatcaa cgtttaatga aactatctcc
    15901 gtttcatttc agatacaaat aaatatagtc gggctccaaa tccgaaaaaa aataccccca
    15961 gtagcttatc ctaagctact ggagatgtat aagtacggtc atataacaac ggggtagggt
    16021 aaataaatga aaaagatgga agaatcatta ttcaataact tttttaaata cttcgttgta
    16081 atcagttacc tgtccgttct taaataccac agaataatct ttttacccat tttcaagtaa
    16141 ccgaagtgga atgtctttac caacttgctc tgtcactgca ttactgatac ctgttagatt
    16201 agctaataaa tctgataaag attgagcatc tgtagaaatc tctgtatcag tatttatcgt
    16261 gattccttta tcttcattta caagcttcca agtaggtggt atagctgtgt atgtttcgat
    16321 gaatgaatca attctttcat ctatcgtctt cccagtatct acttctgtct cattactctt
    16381 agatgaatcg attctttcat ccatcgtctg ctccgtaact gcttctgtct cattattctc
    16441 accggaaact ctcttcacac ccaaacttat atattgtcca tctttagtgt gcatagttaa
    16501 aattcccacg cttttactaa taaattcact ataaccagtt ctttcaatag agacttcaat
    16561 gtatttcaca ctatcatact caaaagaaaa atagacatgt aaaagcattt tgttgtttac
    16621 atctacataa taatcctttg actctacttg agaccttcct atacggaata cagctttact
    16681 gtctgatatc tctataccag catccttatt attaatctgc caatctccaa gtagctcttc
    16741 tggcaagcta gtagtttctt gtgaacactt taccacttca ctggtagagg tcgaaacatt
    16801 cacctccgca ctgttagaag aattttccaa ggaatcagga gccttagcac aaccaacaag
    16861 tctttatata ttgtgcagcc gatattttct tcattcagta cacccttgaa atatgcagtg
    16921 ttagataaag cagttcgtcc tgatttgctg aggcacccat ctcttcttga acgtactcct
    16981 tgattttcaa ggccgcccga tactctttcg gaaaacgctg cttcactgaa gccagcaaaa
    17041 aatcatcctt ctccggcaac tcttccttct taatcattcg ggcaataaaa aactgtaaat
    17101 gcgtcacaaa tcttaagtaa agcatcgaat ctttatcaac ctttttttcg ggaaacagat
    17161 atcctagcat agccaagata tcctttagtg ctcttaccga gagcatggtt tcttccatat
    17221 ttgcttgttc actttgggca tttacaatgt gaaacgcaat gtttccagcc tcctcttctg
    17281 gcaactgaac attcattttt ttgttgatca attggatagc atagcagccg atctcaaatt
    17341 cttttgggta atacttttga atttcaatca gcaggcgatt ttgaaaaaca atgccttttt
    17401 gactgcgttc aatggcatgc ttcaagtgat caaccaaggt aaaaaataga cttttattca
    17461 gcttaaagtc aaacttggcg ttggcataat cgataattcg cttgacgcaa ataattagat
    17521 catccggagc agcctcaaac agtttaatgt aatccttttt tagagcatca gaaagtgaat
    17581 ctaatttaaa tactttttgg attttgtcag ccggaaccaa atcgcctttc tttagttgaa
    17641 atccaatccc tttccccatc aaaattactt ctttgccttg cttatctaag caaagaatta
    17701 aactgttgtt taacgtttta attactctca ttagattcac cgttctctct aagctaagcc
    17761 atttcttgcg attacttttt gataccaaaa gaagctttct ttttttattc gttttaattc
    17821 tttaagattc tcatcggttc ggtcaacata tataaaacca taacgcttat tgaagccttg
    17881 atgggtacta acaacatcaa tcgctgacca aggtaaataa ccaaaaacat ctacaccatc
    17941 tgttaaagct gcttgaatag ccagaatatg tttggctaga taatcaattc gatcctggtc
    18001 attaattcgt ctatcttcct caactatgtc gggtgcccca tagccatttt cagtaattaa
    18061 aataggtaaa tcatagcgat cgtacaattt cctcaatgtt aatcgtagtc cagtagggtc
    18121 aactacccag ccatatggcg ttttatctac ataaggattt tcagctgccc ggtagacacc
    18181 ttcttctccc aacatgatct gttgatcccc cgctctagcg gaaacatctg atccgtcatt
    18241 tttgctggca gcgatggtgg cagttgaata ataattaatc gcaataaaat cgggtttacc
    18301 ggaggataaa attgcctgat cctctgcctc aattttagga tataatccac gatcattcaa
    18361 atagttttca aacaaataat tgtattttcc ccgaactgct acatctaaga aagaccagcc
    18421 tctcaatgtt tcccaattat gggctgcaat tgcatcttct ggactggagg tagcttgata
    18481 catagccgtt aaattgattg ctggaccgat ttttccttta agattcaact gatgatacaa
    18541 gtgaattact ctagcttgag ctaataaaac atggtgatta atttgaaaga gttctttttt
    18601 tgaaggcagc tctccacttg gtggcaaacc aatcgctcca ggatgaagga tcatcgtgtt
    18661 ttgctcatta attgtcagcc aatagttcac cttgtcacca tactcagtaa gcaatacctg
    18721 tacatagtcc acaaaataat cgatagttgc tcgatttaac caaccgccct gctcctctag
    18781 aaaataaggt aaatcgaaat ggtacatggt gacaatcggt tcgattccct gattcaggca
    18841 ttcatcaatt acttgatgat aaaaagaaat tcccttttga ttggttttat tattttcaat
    18901 atccataatt cgcgtccaag cgatggaaaa gcgaaaagct tttaagccta attctttaaa
    18961 cagctgtata tcttctttat agtgatggta aaaatccgag gcaacttcaa aattagctac
    19021 cccttctgta tgctgatact tgtcaataat agacggttgt ttcccatcct cctgataggc
    19081 accctctgcc tggtaggcac taatggaggc accccataaa aacttctctg gaaatgctga
    19141 aagctgtttg tattgcacaa aaatcctctc cttaactaat ttgcatcaat ggttcgtgtt
    19201 cctttaagct tccgcttgct tcactaattc ctgcgtaatt ttcactgttg gtcactacca
    19261 caatcactgt atcatcgtag ccagcgtttc taatggcagc gaaatcggcg ttgattaata
    19321 attgtcctgc tgacacctga tctcctgctt ttacaaatac ttcaaagggt tcccctttta
    19381 aattcacggt gtcgatcccc acatggatca ataattcaat accttcttta gaacgtagac
    19441 caatcgcatg tttagattct aaaatagtaa tgacttctcc ctcaacaggt gaataaatgc
    19501 tgttttcttc tggatgaatg gctacgccct ttcccaatag tcccttagaa aagacagcat
    19561 cgttcacttc agaaatagga cacacggttc cttttaccgg attttcaaca atgactgctt
    19621 cggctattgc cgtttgctct gattcatcag aagtatcgtc aaatccaatt agataagcaa
    19681 tgataaaggt tgcaacaaag gcgattacac acgtaataat tgcgtgaaca atattcattg
    19741 gattttctcc aataaaggct ggtaaggctg ctaagccagg ggaaacaaag gcatatctga
    19801 ctaaaccgct caagccagca tacaaaccag caattgcacc accaatcatg gaagcaacta
    19861 atggtttttt cagcttcaag gttactccat agagtgaagg ctcagtaatt cccattaaag
    19921 cagtgatccc agtggacaca gctagctgct tcaactcttt gtttttagtt ttcgcggcta
    19981 cagcaaaggt agcacctgat tgagcaatat tagaagccag cattcctggc ccattgatca
    20041 tttcagaacc cgtactgctc aattgcatag tagcgattgg cgtcattgcc caagctgtac
    20101 ccgtaaccac caaaaatggc tgcaaaccac ccatcaaaaa tggaattaac caagctgctt
    20161 tgccgttaat ccattcagcc cccattgcta taagatcgtt cagcaacgtt ccaaacggtc
    20221 caatgacaac caacgctaaa ggccccataa ttaaaaatac cagcatcggc ttagtaaaga
    20281 atttaataaa cgaaggcgaa attcgatccg caaagggctc tacataggac atgatccaaa
    20341 cagtaaagat aatcggtaaa actgatcccg cataatctgc agctaatacc ggaattccta
    20401 gaaaagaaac ggcatcgcca gtagaaaaaa gctgtgaaat atttggatga agcaaaatgc
    20461 cagcaacagt aatcgccaaa attgggttga catcaaactt tatggctgcc ccataggcta
    20521 atagtactgg cataaaataa aaggctgcat cagcaatagt attcaaaatg atgtaagttt
    20581 gactactgtc tgatagtaca ccagtcaaag tcaagacggc caaaatggct tttaccatcc
    20641 cggcacctgt tatagctgga atcatcggtg taaaggtggt agaaatgaca ctaatcaatc
    20701 ttgaaataat actttcttga ttgtctgaag aggggccctt tttaattgaa gttcccactt
    20761 ccttttgaat ttccttgaag gctgtttgga cttcattgcc aatcaccact tggtattgtc
    20821 caccgctatc caccacacta attacaccaa gtgttttttc taaggctttc gtatcggctt
    20881 tccttttatc tttgagttca aaacgcagtc tggtggcaca atgggttaag ctgaccacat
    20941 tttcttttcc cccaacctgt tgcaatacat ttcttcctac ttctctgtaa tccattattc
    21001 tctctcctta aagcagtaaa aaagaccaag tcaaaccacg ccccaatcaa cattgaagtg
    21061 ttagtttgtc ttggtcttgc ctgcataatc agtaacatgc caataacgtt attttgctgt
    21121 aatccaataa tagcacatta tgatagcgca atcaacaggg aatttaattt tttatctttt
    21181 cgtttgaccg tatagggtaa tataacagtt agatcacatc aactagggta tatctgcgta
    21241 tacttactgc taaaataagt atatctaata ttaactatac cagtaaaacc attcctacat
    21301 aaccagcggg aaattcccaa aatcgtgaaa gcatcaaaaa tgcatataac ggatcacaca
    21361 acttcaacaa ttctgctctt gggaaaaatt gatgaatttg gtgagtaaag gatggaataa
    21421 acagcattcc aacaatatag gcaacaatag tgatacttgt ttttttggta aaaatcagta
    21481 agcaatagcc aatttcaatc attccgagat ataaaggtat caatagaatg atttgggcta
    21541 gtattcttaa aaattaacta gcaaatgttt aaactgattt atttctaatc tacatgtagt
    21601 aagtatttca attc
//
LOCUS       DAYNVV010000046        21592 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.046, whole genome shotgun sequence.
ACCESSION   DAYNVV010000046 DAYNVV010000000
VERSION     DAYNVV010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21592
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.046"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            103..1527
                     /locus_tag="ACGXWR_001948"
     CDS             103..1527
                     /locus_tag="ACGXWR_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFK0803500.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            complement(1569..1826)
                     /locus_tag="ACGXWR_001949"
     CDS             complement(1569..1826)
                     /locus_tag="ACGXWR_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803501.1"
                     /translation="MPIRILTALVNKITIRKAFYISSAFFLFSNQTYNHLFLFKNVGV
                     IQFCCKHLFYLHIVNGRTNNGFFLVSLYRILFPKKKKQLEI"
     gene            1988..3097
                     /gene="pdhA"
                     /locus_tag="ACGXWR_001950"
     CDS             1988..3097
                     /gene="pdhA"
                     /locus_tag="ACGXWR_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HFK0803502.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            3100..4077
                     /locus_tag="ACGXWR_001951"
     CDS             3100..4077
                     /locus_tag="ACGXWR_001951"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HFK0803503.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            4102..5745
                     /locus_tag="ACGXWR_001952"
     CDS             4102..5745
                     /locus_tag="ACGXWR_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HFK0803504.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            5753..7159
                     /gene="lpdA"
                     /locus_tag="ACGXWR_001953"
     CDS             5753..7159
                     /gene="lpdA"
                     /locus_tag="ACGXWR_001953"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFK0803505.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            7321..7596
                     /locus_tag="ACGXWR_001954"
     CDS             7321..7596
                     /locus_tag="ACGXWR_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HFK0803506.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            7602..8369
                     /locus_tag="ACGXWR_001955"
     CDS             7602..8369
                     /locus_tag="ACGXWR_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HFK0803507.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            8537..10366
                     /gene="typA"
                     /locus_tag="ACGXWR_001956"
     CDS             8537..10366
                     /gene="typA"
                     /locus_tag="ACGXWR_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HFK0803508.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            10627..12399
                     /gene="recQ"
                     /locus_tag="ACGXWR_001957"
     CDS             10627..12399
                     /gene="recQ"
                     /locus_tag="ACGXWR_001957"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HFK0803509.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            12513..12815
                     /locus_tag="ACGXWR_001958"
     CDS             12513..12815
                     /locus_tag="ACGXWR_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HFK0803510.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            12818..13981
                     /locus_tag="ACGXWR_001959"
     CDS             12818..13981
                     /locus_tag="ACGXWR_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFK0803511.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            14007..17435
                     /locus_tag="ACGXWR_001960"
     CDS             14007..17435
                     /locus_tag="ACGXWR_001960"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HFK0803512.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            17456..18580
                     /locus_tag="ACGXWR_001961"
     CDS             17456..18580
                     /locus_tag="ACGXWR_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP-associated domain-containing protein"
                     /protein_id="HFK0803513.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            18561..19007
                     /locus_tag="ACGXWR_001962"
     CDS             18561..19007
                     /locus_tag="ACGXWR_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFK0803514.1"
                     /translation="MIAVIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESA
                     KVCQLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQ
                     LQSLLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            18991..19329
                     /locus_tag="ACGXWR_001963"
     CDS             18991..19329
                     /locus_tag="ACGXWR_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HFK0803515.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            19448..20008
                     /gene="rsmD"
                     /locus_tag="ACGXWR_001964"
     CDS             19448..20008
                     /gene="rsmD"
                     /locus_tag="ACGXWR_001964"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HFK0803516.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            20005..20496
                     /gene="coaD"
                     /locus_tag="ACGXWR_001965"
     CDS             20005..20496
                     /gene="coaD"
                     /locus_tag="ACGXWR_001965"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HFK0803517.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            20486..21529
                     /locus_tag="ACGXWR_001966"
     CDS             20486..21529
                     /locus_tag="ACGXWR_001966"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HFK0803518.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
BASE COUNT         7320 a         3751 c         4741 g         5780 t
ORIGIN      
        1 atttttgtca cagtccctta tgttttgcaa aaaaagtttt tcttttttct cgtaaattcg
       61 gtaaaatcaa aagaaaaaat agacaataga aaagagaagc ttatgtggga aaaagtagag
      121 aaaaaacaag gaccgattta tcgtcaaatt atggaacaga ttatgagaga aatcgaaaac
      181 ggaaggatca atcctggaag tcaacttgaa tcagaacgaa aactagggca actttttggt
      241 gtgaatcgtt ccaccgttgt ccatgcattg gaagagctta gggagcttgg ggtactaacg
      301 agcaaacgtg gcagcggatg gtttgttaat cagactgaat gggggaaatt cgctgttcca
      361 agaatcgatt ggcggcaaat gatctctcct cgttatgagc agacggactg gtatgagcaa
      421 aaaataagag aagcaaagca gatccaaaaa acatcgtttc ttgatttata cgctagcgag
      481 atgccagatg agcttttgcc gaattttgag tttccttctt attctcttga agaaatctta
      541 gcggaagaaa aagaaatgga tcttttaggc tatactccgt tacgtaacaa aatcaaacgg
      601 tatttggaaa gtaaatttga attggcattt tcccccaacc agcttcttgt gactggtggc
      661 ggtcagcaag caatcttttt gattttacaa acgattcttt cagctggaga ggggatagct
      721 gtagagtcac cttctttttt ttaccgatta cctcttttca aagcttcagg aacgcgttta
      781 tttgggatac cgatggatga agaagggatc gacttagaaa aactgaaaga atcgatccat
      841 aaaaataaat tgaaagcagt gcttatcaac ccgaattttc aaaaccctac aggaaaagtg
      901 atgagtcaaa aacgacgaga aaagctagta gaattgtgtc gacagtatcg gcttccaatt
      961 attgaagacg atgtatttac ggatctttca tttctaaacc aagaagaagt ccttcctata
     1021 cgaacgattg atccggataa tgtgttatac gtcggttcgt tatctagggt tttaggaaaa
     1081 acaacgaaaa tcggttgggt gataggacct gagactttta tctcgcaact agctcaagcg
     1141 caagaaatga tggagttttc gatgaatatc cttacacaaa tcacagtggc taatgtattt
     1201 aatgaagcaa ttgatttgaa aatgcaagat gtaagaaaaa agttgaaaga aaaaagccga
     1261 ctgataagcg cttggggaga ttcacaatcg tttttcaagc ttcattcaat tttaggtggt
     1321 tactatgcct ggattacttg ggatgggaaa aaactagacc ccgaactagc agaaaaagta
     1381 gtagatatgg gtcttggaat tgcaccaagt ctactttttg ggcaagatat aaatggaatc
     1441 agaatcaatt acagtaggct ggatgaaaac caaataccgt tgttttattc aaagatgaaa
     1501 attctagaaa agtggttaac agaataattt cacaaagtaa atagattaaa gaatataaca
     1561 gcttggattt aaatttcaag ctgtttcttt tttttcggaa aaagaatacg atataaagaa
     1621 actaagaaaa aaccattatt tgtacgtccg ttcacgatgt gtaaataaaa taaatgtttg
     1681 caacaaaact gtataacacc aacgttttta aatagaaaca gatggttgta agtttgatta
     1741 gaaaatagaa aaaatgcaga tgaaatataa aacgctttcc ttattgtgat tttattcact
     1801 aatgctgtta atatgcggat tggcataatt tcctttcatc gtgaaaattt gtgcttttag
     1861 cttgtatttc tcataaatcc atgataattt attaatgaag acggttaaat agtgatacag
     1921 ttttattcac tgtttcaatc gcagaatgaa gagattttct tatagatgag agaggaatgt
     1981 gtgacaaatg gcaaacaaaa aagcaccgat cgacttccaa gcactgctag atgaagtcaa
     2041 tgcagatttc ccagtatatc aagcacttga tcaagatgga aacgtagtta acaaagattt
     2101 agtacctgat ttatccgatg atgaactcgt tgaattaatg actcatatgg tatggtctcg
     2161 tgtattagac caacgttcaa cagcgctgaa ccgccaagga cgcctaggct tttttgcacc
     2221 aactgctgga caagaggcaa gtcagctggc tagtgcttac gcatttgata aagaagatgt
     2281 tcttcttcca ggttatcggg atgtacctca actagtaaaa catggtttac ctttatctca
     2341 agctttttta tggtctcgag gacatgctgc aggtaattct tatccggaag aattgaaagc
     2401 tctaccacca caaattatca tcggtgcaca atatgtacaa gcagccggtg ttgcattagg
     2461 tttgaagaaa cgaaacaaga aaaatgtcgt cttcacttat actggtgatg gcggttcatc
     2521 acaaggtgat ttttacgaag caatcaattt cgctggcgct taccatgcaa atgccgtatt
     2581 ttatatccaa aacaacgggt atgcgatctc tacacctcgt gaaaaacaaa ctgcagcaaa
     2641 aacacttgca caaaaagctg tcgcagctgg gattcctggt attcaagtcg atggaatgga
     2701 tccgcttgca gtatatactg tatctaaaat ggcacgggaa tgggcgatca gtggaaatgg
     2761 accagtccta atcgaaacac tgacttatcg ttatggacca catacactat ctggtgacga
     2821 tccaacccgc taccgtacaa aagacacaga tgacgattgg cagaaaaaag atccattgat
     2881 ccgcttccgt aaatatttga cggaaaaagg actttggtct gaagaaaaag aagaacaagt
     2941 catcgaagca actaaagaag aaatcaaagc agctattgct gaagccgaca aagtaccaaa
     3001 acaaaaggtt tcagatttct tgaaaaacat gttcgaagta tctccacaat caatcaaaga
     3061 acaaattgca atttatgaag cgaaggagtc gaaataatca tggcacaaaa aacaatgatc
     3121 caagcaatca cagatgcctt agcacttgaa ctagaaaatg acgagaatgt cgttgttttt
     3181 ggtgaagatg ttgggaaaaa cggaggagtt ttccgggcaa ctgaaggatt gcaggaaaag
     3241 ttcggagaag accgagtatt cgatactcct ttagctgaat ctggaatcgc aggattgagt
     3301 ttcggtcttg cgttagaagg atttcgtcca gttcctgaaa tccaattctt tggttttatt
     3361 ttcgaagcaa tggacgaagt agtagctcaa atggctcgta caagatatcg aatgagcggc
     3421 actagaaatc tacccatcac aattcgttcg ccatttggtg gcggtgttca tacaccagaa
     3481 ttgcattcgg ataatttaga aggtttgatc gctcagtctc ctggtattcg agtagtgatt
     3541 ccttccaacc cttatgatgc aaaaggacta ttgatttctt ctattagaag taacgatccg
     3601 gttgttttcc tagaacacat gaaactatat cgctcattcc gagaagaagt gccggatgaa
     3661 gcttacgaag ttcctttgga taaagcagca gttactcgtg agggaacaga tgtatctatt
     3721 atcacatacg gagcaatggt gcgtgaagca atcaaagcag cagacaatct tgcaaaagaa
     3781 aatatatctg ttgaaatcat tgatcttcgt acagttgcgc cattagatgt agaaacgatc
     3841 attcaatccg tggaaaaaac tggtcgcgta gttgttgtcc aagaagcaca acgacaagcg
     3901 ggcgttgccg cgcaagtagt ttctgagatc tcagaacgcg ctatcctttc attagaagcc
     3961 ccaatcggac gagtttctgc acctgataca gtcttcccat ttggacaagc agaaaatgtc
     4021 tggttgccaa atgcaaaaga tatcgaagac aaagtaaaag aaatcgcgga attttaagaa
     4081 aagaagggac gaaacaaagt catggcttat caatttaaat tgccggatat cggtgaagga
     4141 atcgcagaag gtgaaatcgt caaatggttc gtcaaaccag gagatacgat caatgaagat
     4201 gatacattac tagaagttca aaatgacaaa tcagtagaag aaatcccgtc acctgttaca
     4261 ggaacggtta aaaatgtgat tgttccagaa ggtaccgtag caaatgttgg ggatgtatta
     4321 gtagaaatcg atgcaccagg acacgaagac aatgaagggg acagtggtgt agccgcagaa
     4381 tcccaaactc cagctaaacc ggctgctgaa cccactgttg atacagaatc agctggatcg
     4441 tcaagcgaag gagtcttcca atttaagtta ccggatatcg gtgaaggaat cgcagaaggt
     4501 gaaatcgtca aatggttcgt caaaccagga gatacgatca atgaagatga tacattacta
     4561 gaagttcaaa atgacaaatc agtagaagaa attccgtcac ctgtcacagg gacagttaaa
     4621 aacgtgattg ttccagaagg cactgtagca aatgttgggg atgtattagt agaaatcgat
     4681 gctcctggac acaatagtgc accgtcaact agtgcgccat cagctgaagc accaaaagaa
     4741 aaagtggaaa catcaggttc agcaagtgtc gttgaagctg ccgatccaaa taaacgtgta
     4801 ttggctatgc catctgttcg tcaatttgcc cgtgaaaaag atgtagatat ctcacaagta
     4861 actgcaactg gaaaaggtgg cagagtaaca aaagaggaca tcgaaaactt cttggcaggt
     4921 ggtccaagca gtgcaccagc gaaatcagaa gcgccagaag cggcagcacc gaaagaagca
     4981 gctcctgcag cagaaagcaa accagctgca ccagcaaaac cattcaagtc caacttagga
     5041 gacttggaag aacgtgtagc aatgacgcca acacgtaaag ctatcgctaa agcaatggtc
     5101 aacagtaagc atacagctcc acacgtgaca ttgcatgatg aagtagaagt gtctaaacta
     5161 tgggataatc ggaaacgatt taaagaagtt gctgctgcaa atggtacgaa acttactttc
     5221 ttgccatatg tcgtgaaagc tttaacagcg actgttaaga aatacccagt attgaatgca
     5281 tctatcgacg atgcaaacca agaaatcgtt tataaacatt actacaatat cggtattgca
     5341 actgatacgg atcacggact atatgtacca aatgtgaaag atgcagaccg caaaggaatg
     5401 tttgctattg cagacgaaat caatgagaaa gcaaaattag ctcatgacgg caaactatct
     5461 gcagaagata tgcgcaatgg aacaattacg atcagcaata tcggatctgt aggtggcggt
     5521 tggtttacac cagtcatcaa ctatccagaa gtagctattt taggtgtagg aacgattgca
     5581 caacaaccaa tcgtaaatgc tgaaggcgaa atcgttgtcg gtcgtgtgat gaaactgtca
     5641 ttaagtttcg atcaccgtat cgtagatgga gcaactgcgc aacaagcaat gaataatatc
     5701 aaacgtcttt tagctgatcc agagctatta atgatggaag gatgataaac aaatggtagt
     5761 tggagatttt gctgtagaat tagatacagt tgtaattggt gcgggacctg gtggctatgt
     5821 agctgccatc cgcgctgctg aaatgggaca aaaagtagca atcattgaaa gagagtatat
     5881 tggcggtgtt tgtttgaatg tcggctgtat tccttcaaaa gcactgatag ctgcaggaca
     5941 ccattatcaa gagtcactag attctgaaat gtttggagta actagtgaaa acgtcaaact
     6001 agattttgca aaaacacaag aatggaaaga aaacaaagtt gtccatacgt tgacttctgg
     6061 tgttggtttc ctattaaaaa aacataaggt tgaaacaatc gaaggagaag cgttcttcgt
     6121 agatgatcac acactacgcg tcattcatcc agattcagct caaacttatt cgttcaataa
     6181 cgcaatcatc gcaacaggtt cccgtccaat cgagattcca ggatttaaat tcggaggacg
     6241 tgtgttagat tctactggcg gattagcatt gaaagaagta cctaagaaat ttgtgatcat
     6301 cggtggcggt gtgattggtg ccgaattggg cggagcgtac gcaaacttag gagcagaagt
     6361 aacgattctt gaaggctcac cacaaatttt accaacttac gaaaaagatc tagtaaaatt
     6421 agtagaagat gatttcaaga aaaaaggcgt aacagtcgta acgaatgcaa tggcgaaaga
     6481 agcagtcgat aacggtgaca gcgtgacagt gaaatatgca gtggacggga aagaagaatc
     6541 cgttactgct gattatgtga tggtcactgt aggtcgtcgt ccgaatacag atgatatggg
     6601 cttagaacaa gcgggtgtcg aagtaggaga acgaggattg atcacggtgg ataaacaagg
     6661 acgtacgaac gtacctaaca tctatgccat cggtgatatc gttccagggg cggcattagc
     6721 acacaaagcc agttatgaag caaaaatcgc tgctgaagca atctctggca aaaaagtagc
     6781 tgtagattat aaagcaatgc cggcagtagc cttcactgat cctgaattgg cttctgtagg
     6841 tatgacgatc aaagaagcaa aagatgctgg tatcgaagca aaagcatata aattcccatt
     6901 ttcagggaac ggtcgggcat tatcgcttgg taaaacagaa ggattcatcc gtctagttac
     6961 gacgatcgaa gataacgtgc ttattggcgc gcaaatcggt ggagtcggcg caagtgatat
     7021 ggtctctgaa ttagctttag caatcgaatc aggaatgaat gctgaagata tcgccttgac
     7081 gattcatcct catccatctc ttggcgaaat cgtcatggat gcttcggaat tagcattagg
     7141 tttaccaatc catatttgat ttgaataata caggcgaaac gcaactgaaa aatcagttgc
     7201 gttttgtttt ttagaattat caataatatt attatgtaaa cttaaaaata tgacaacttc
     7261 ttggtttatt accacttcct atgctacact gaagaggaat atgaaatagg agagttgaag
     7321 atgcaagaat atcagtatcc acttgattta gattggacaa cagacgaaat ggtcattgta
     7381 atgaagatgt gggaagatct ggaacgtgcg aatgaaaaag ggataaacaa tgaagctttt
     7441 ttgaagactt atcagcagtt taaaactgtt gtcaaatcca ttggtgagga aaaacgattg
     7501 ggacgggaat ttgaaaaagc ttccggttat tctttatatc gtacagtgca gcaagcaaaa
     7561 aaaaatccaa acaaaacttt gagaatgaac gggtgagata aatggaacag atgattgatc
     7621 atatcaagtc ctggcttgaa gaagctggtg agaaaatcaa atcttctcaa caaacattaa
     7681 caatctcgca aaaatcaaat cgaacggatc tagtaacaaa tgtcgatcga aacatccaga
     7741 attttctaat cgaaaaaatc cattcctttg atccagaggc gaaaatattg gcagaagaag
     7801 aagggtgtaa tcaattatcg gatctcgatg gaagagtctt tatcatcgat cctattgatg
     7861 gcaccttgaa ttttgtgatt gaaggggaaa atttttgtat tatgctcgct gtttatgaat
     7921 ccggcgttgg aaagcttggt ttcatttatg acgtgatgag aaatgaactt ttttggggtg
     7981 gaaaaggaat aggcgtgtat aaaaatgatg agccattgcc tagaccagca aataaatcct
     8041 tatcggaagg cttacttggt gtgaatagtt atcttttcgg tcataataaa tatggaatcc
     8101 gagaaattgc ggaaagcagc atggggacac gtatgtacgg atgcgctggt cttgaactag
     8161 tggcaatctt gaaaggaaac cacattgctt atatttcaaa ccttagccct tgggattatg
     8221 cagcgggaaa tgtcttattg gaagagtttg gtatggtaac aagcggtctt tttggtactc
     8281 ctttgacatt tgaaaaaagg gaatactatt tagcagggac ttcttgtgca tatgcagaaa
     8341 tcgcagacct tttgaaaaaa gaaggctgaa aaaaaggtag aaatcattca caaaaatgat
     8401 aaaaacgagc aaaagattaa ttttctcgaa aaaatgaaaa cattttacta tatttcatga
     8461 aaaaagtctg ctataattag cagtcgagta aaatttgccc tgtcataaag aaccaataaa
     8521 aaaggagtta gttacattga attatagaaa cgatatccgt aacgtcgcaa ttattgccca
     8581 cgttgaccac ggaaaaacaa cattagttga tgaactatta aaacaatcag atacattaga
     8641 cgcacatacg caattgcaag aacgtgcgat ggactcaaat gcgctagaaa aagaacgtgg
     8701 tatcacgatt ttagccaaaa acacagctgt agactataaa ggtattcgcg taaacatcat
     8761 ggatactcca ggacacgcgg acttcggtgg cgaagtagaa cggatcatga aaatggttga
     8821 cggcgttgtg ttggtcgtag atgcgtatga aggaacaatg cctcaaacac gttttgtatt
     8881 gaaaaaagca ctggaacaac atatcacacc aatcgttgtc gtaaacaaga ttgacaaacc
     8941 ttctgctcgt cctgagcatg tcgtagatga agttcttgaa ctattcatcg aattaggagc
     9001 agatgatgat cagttagact ttcctgtgat ttatgcatct gcactaaatg gtacgtcaag
     9061 cttgtcagat gatccagcag atcaagaacc aaccatggca cctatttttg atacaattat
     9121 tgaaaaaatc cctgctcctg tcgataacag cgacgaacca ttacaattcc aagtttcatt
     9181 acttgactac aacgattatg taggtcgtat cggaatcgga cgtgtattta gaggaacaat
     9241 caaagtagga gaccaagtag cattaattaa attagacgga acagttaaga aattccgtgt
     9301 aacgaaatta tttggtttct ttggactaaa acgtctagag attcaagaag caaaagctgg
     9361 agacttgatt gctgtctcag gtatggaaga tatctttgtc ggtgaaacag ttactcctgt
     9421 ggatcatcaa gatgcgttac ctatccttca cattgacgaa ccaacattgc aaatgacttt
     9481 cttagttaat aattcaccat ttgccggtcg agaaggtaaa ttcgtaaccg ctcgtaagat
     9541 tgaagaacgt ttgatggcag aacttcaaac agatgtatcc ttacgagttg aaccaacaaa
     9601 ctctccagat gcatggacag tttctggtcg tggagaattg catttgtcta tcttgattga
     9661 aaacatgcgc cgtgagggat acgaattgca agtatctcgt ccagaagtta ttgaaaaaga
     9721 aatcgacggt gtaaaatgcg aaccgtttga acgcgtgcaa atcgatacac cagaagaata
     9781 tatgggtagt gttatcgagt ccttgagctt acgtaaaggt gaaatgcaag atatggtcca
     9841 tacaggaaac ggacaaatcc gtttgacatt cttaacacct gcccgcggtt tgattggtta
     9901 ttcaactgaa ttcctttcaa tgacacgtgg ttacggaatc atgaaccata cttttgacca
     9961 atatctgcca atgcttcctg gtcaaattgg cggacgtcac caaggggcgc ttgtttcgat
    10021 cgatacagga aaagcaacga cttattctat catgagtatc gaagaacgcg gtacagtctt
    10081 cgtagaacca ggtacagaag tatatgaagg aatgattatc ggggaaaaca gccgtgataa
    10141 tgatttgact gtcaacatca cgaaagcaaa acaaatgaca aacgtacggt ctgctactaa
    10201 agaccaaaca tctgtcatca aaaaaccaaa acaattgacg ttggaagaat ctttggaatt
    10261 cttgaatgat gatgaatatt gcgaagtaac accagaaagc attcgcttga gaaaacaaat
    10321 tttagagaaa aatgctcgtg aaaaagcatc taaaaagaaa aaataatctg taaaaggatg
    10381 aagagagaaa ccagcttgtt ataaaaaata gctggtttct ttttttgtcc aactcttttc
    10441 tgtggagaag tcatctttgt caatggacat aaattcagaa aatacgccga aagacgttta
    10501 aaagactttt aaaaaactta tttctagaga gtttttgttt cataataaga taatgtttca
    10561 cgaaaggaga tcaacttgtc cttcgaagaa aatcgaagta aaatggcaag agaaaggagc
    10621 gggaagatga acgacttatt aaaacaatac tttggctatg atgagtttag acctggtcaa
    10681 aaagaaatta tccagaaagt cattgatcag gaaaatgtat taggaatcat gcctaccgga
    10741 agtgggaaat caatctgtta ccagcttcca gctttactat tagatgggct tactgtggtt
    10801 gtgtcccctt taatctcttt gatgaaggat caggtggacg cggcgaatca attaggtata
    10861 cccgccactt ttatcaatag ctcgttagat ggttacgaaa cagctagacg cttccaagaa
    10921 atcgatagac agcagtaccg tttactttat atcgctcctg aacgttttat catgccggat
    10981 tttatccaag caatgaagcg atggaacgtc cgtatgatcg ctattgacga ggcacattgt
    11041 atctctcagt gggggcatga tttccgccca agttatttac agatggcgaa ccagctagat
    11101 caactgccaa atcgtcctgt aattgttgct ttgacagcta cagcgactgt gcaagtagct
    11161 gctgacataa aaagactttt aaaaattcca gaaaacaacc atattcagac tggttttgaa
    11221 cgagaaaatc tacgatttca agtaattaaa gatcaaaaaa aagaacaata tctaatcgaa
    11281 tatttaaaga tcaacaaaaa tcaatctggt atcatttatg cagcaacgag aaaagaagta
    11341 gaccgtctct atcatttgct taaaaaattc gatttttccg tgggtagata tcatggtggt
    11401 ctaaatgaga atgagcgaac agaaatgcaa gaagcctttt tatacgatcg cttgcagctg
    11461 attgtagcga caaatgcatt tggtatgggt ataaataaaa gcaatgtccg ttttgttatc
    11521 cattatcaaa ttcctggctc tctagaagca tactatcagg aagctggtcg ggcgggaaga
    11581 gatggtcttt ccagtgaagc catcctgctt ttctctcctc aagatatcca agtccaaaag
    11641 ttttttatcc agcagtccca aagagaagaa gggcaaaagc aaaaagaata tgaaaaatta
    11701 aaagcgatga cagaatacgt gtatattgag tcctgtcttc agcaatacat cctaaactat
    11761 tttggcgaga caagcagtcc gtgcaaccgt tgtggtaact gtttagatga cagagaaata
    11821 gtagaagtaa cgacagaagc acagatggtt ctttcttgct taaaacgtat gggtgagaac
    11881 tatggtaaac aaatgctgat gaaagtctta gcaggatcga aagaacaaaa gctgcaagct
    11941 ttaggttttg gacatttatc tacctatgga ctgatgaaaa accaatcgca aaaagaaacg
    12001 atgcagttaa ttgaatattt gatatcgaat ggctatcttc tgaccatcaa tggtgagtat
    12061 cctgttttga aagtaacaga aagagggata caagtattga aaggacaaga atctgtttat
    12121 cgaaaggaac ccaagaaagt ccagcagcta tcggatgaag aaaccgatac actatttgaa
    12181 gtgctgcggg aactgcgaac ggatctagca tcagaagcag gcgttccccc gtatgtcgta
    12241 ttttcagatt ccacattgaa agaaatgagc cgaatacgtc catcaagcag attggagatg
    12301 cttcagataa aaggagttgg ccaaagcaag cttgataaat atggcgaagc ctttttatct
    12361 cggataaaaa atgcggactc taacgttctg gataagtaga aagaacgaat acgtaaaaat
    12421 gaataaaaac aactggttaa atctgttttt tttgctcctt atgaaaatca aatatgttat
    12481 aattaaggaa ttagaatggg aggtaagcac agatggattc tttgtcgaaa aaacttgcga
    12541 tccaagtatt aaatgatgaa gcagaacgga tcaaacgatt aatccgaaat caaaacaaca
    12601 gtctctgtat ctcacaatgc aaagccttcg aagaagtggt agatacacag atgtacggct
    12661 tttcccggca agtcggtttt gctgtccgta taggagtaat cggaaagaac gagggccagc
    12721 tgatgttaag tgagctagaa cgagaattga atcagttata tagtgaggtt taccaagaaa
    12781 tttatgataa aaaagaagtt ggcaaggagg aatagacttg cctaagaaag tgaaaaaaag
    12841 gcatctatta gactatagca tcttgattcc ctatttaatt ttatgtgtat tgggattgat
    12901 catggtatat agttctacgt cgtatctatt attagaaaac ggacaaaatc cgtccgcatc
    12961 agtcattaac cagagtattt tttgggtgct tagcttgatt gctatcgcac tactttataa
    13021 aatgaaaaca gatgttttga aaaaccagcg tttgatcatg gcagccatcg cagttttgac
    13081 gattttgctg ctgattgttg tgttttttgg taaggagatc aatggggcga aaggttggct
    13141 gcaaattgca ggattctcga tccaacctgc cgaataccta aaaatcattt ctatctggta
    13201 cctgtctctg actttatcta aaagacaaaa cagtgtacaa aaagattttc ttgggactgt
    13261 gaaacgtcca cttgcaatgg ttatcggact tactgcatta gtcgctattc ttcccgattt
    13321 tggtaatgcg gcagttatct ttttgattat tttggttctg cttttagcca gcggagtcaa
    13381 ttatgtgtat actttgattg taggagtagg aggcttttgt ctaagtactt ttacgatctg
    13441 gctgatcaat atcacaaacg gaaagatctt acccggacgt ttacagtata tctataatcg
    13501 atttgctatt taccaaaatc ctttctcaga cgaattaaat aaagggcatc aactagtcaa
    13561 cggctactat gccatgttca acggaggact atttggcagg ggattaggta acagtatcca
    13621 gaaaaaagga tttttacaag aagcacaaac cgattttatt tatgcaatcg tagtggaaga
    13681 actgggagtg attatgggga ttttgatatt agcgttgcta ttctttatga ttgtgcgcat
    13741 tgtccttgta ggtatccgtt caaaagatcc gttcaattcg cttttgtgca ttgggatcgg
    13801 cgcaatgttt ttgatccaag tatttgtcaa tcttggagga attactggcg ttattccttt
    13861 gacagggatc acgttcccat ttttaagtca aggaggctcc agtttgctga tgctttcgat
    13921 ttgtgtcggc tttgtcctca acatcagtgc ggatgaaaaa cgcaagagct taggtttata
    13981 ataaaaaaag atgtaggagt ggttcgatga aaaaagtttt agttgctaac aggggtgaaa
    14041 tcgctgtacg tgtatttcgt gcttgtacag aattaggaat taaaactgtt ggaatctatg
    14101 cagaagaaga tgaatattcc gtacaccgtt tcaaagcgga tgaagcatat ttagtaggac
    14161 aaggaaaaaa accgattgat gcgtatctag atattgaagg gatcatttct atcgcgaaag
    14221 aatgcggagc tgacgctatt catccgggtt acggtctttt gtcggaaaac ttgaattttg
    14281 cgcaacggtg cgaagaagaa ggcatcattt ttgttggacc caaactgcat catttagata
    14341 tttttggaga taaaatcaaa gcaaaagctg cagctatcga agcggggatt gcttcgattc
    14401 caggcacaga tggaccaatc gcttctatag acgatgcctt ggagtttgcg aaacaatacg
    14461 gttatccgat tatgatcaag gcagctctag gcggcggcgg acgcggcatg cgtgtagctc
    14521 acgatgaaaa gagtgcaaga gagggctacg aacgtgcgaa aagcgaagca aaagcagcct
    14581 ttggtagtga tgaagtgtat gttgaaaaat acatcgctaa tcctaagcat atcgaagtac
    14641 agattctcgg ggatacgcat ggaaacgtca tccatctttt tgaaagagat tgttctgttc
    14701 agcgccgtca ccaaaaagta gtagaagtag cgccttgtgt ctctatgaat gaacagcaac
    14761 gtcaaaaaat ctgccaggca gctgtccaat tgatgaaata tgtcgggtat gtcaacgcag
    14821 gtacagtaga atttcttgtt gaaggagatg atttttactt tatcgaagtc aaccctcgcg
    14881 tccaagtgga acatacgatc acagaaatga ttacagatat tgatatcgta acaacgcaac
    14941 tgttgattgc tcaaggtttg gatctgcata aagaaatcgg attgcctcag caagaaggaa
    15001 ttaaattaaa tggttcagcc attcaatgcc gaatcactac agaagacccg ttgaataact
    15061 ttttaccaga cacagggaaa atcgatacgt atcgttcacc tggtggtttt ggcgtacgtc
    15121 tggatgtcgg aaatgcttac gcgggctatg tagtgacacc gtattttgat tcattgctag
    15181 taaaagtatg tacgcatggt gctacctttg aaacagccat tcagaaaatg gaacgttgct
    15241 tgaaagaatt tagaatccgt ggagtgaaaa caaacattcc atttatgctc aatgtcatca
    15301 cacatcctga attccaatca ggaaatgcaa aaacaacctt cattgatagt acagcaacat
    15361 tatttgaatt tcctcgacta cgagaccgcg gaaacaaaac gatgaaatat atcggtgaaa
    15421 ttactgtgaa tggttttcca ggtatcgaaa gtggcgaaaa accattttat gaagaaccac
    15481 gtatgcctaa agatctaatc acaagaactg attacgtaac ggctaagaat gtattagatg
    15541 cgaagggtgc cgatgctttg gtcgaatgga tcaaaggaca ggaaaatttg ttgttgacgg
    15601 atacgacatt tagagacgcc catcaaagtc tgctagcaac tcgtgttcgg acaaaggatt
    15661 tcaagcagat tgcacgtttg actggagaag gtcttcctga actcttttca agtgagatgt
    15721 gggggggagc aacatttgat gtggcttacc gctttttgaa tgaagatcct tggcaacggt
    15781 tgagaaaaat tcgttcttta atgcctaata cgttgctgca aatgcttttc agaggttcaa
    15841 atgccgttgg gtattctaat tatcctgaca atgtattggt ggaatttgtc aaagaagcag
    15901 cagcgcaagg aatcgatgta tttcgaatct ttgatagttt gaactggact ccacaaatgg
    15961 aaaaaagtat ccaagctgta cgggatactg gtaaaatcgc agaggcagct atttgctata
    16021 ctggcgatat caacgatcca agtcgggcaa aatacaatgt tcagtattat aaagacatgg
    16081 caaaggaact agaacaactg ggtgcgcata tcattgcaat caaagatatg gctgggctgc
    16141 ttaaaccgca ggcagcttat cgtttgatta gtgaattgaa agaaacgaca gatctgccaa
    16201 tccatctgca tactcatgat accagcggga atggaatcat cacttattct gctgcttcaa
    16261 aagcaggagt agacatcgtt gacgtggcaa tgagtgcaat gagtgggaat actagtcagc
    16321 ctagcatgag cagcttgtat tatgcactgg tcaatggtcc acggctgcca gaaatcacga
    16381 ttgaaaatgc acagaaatta aaccattatt gggaagatgt gcgcatgtat tacaaaccgt
    16441 ttgaaaacgg cttgaatgct cctgaaacag aagtatatat gcatgaaatg ccaggaggac
    16501 agtattcgaa tctacagcaa caggcaaaag ctgtcggatt aggtcatcgc tgggatgaaa
    16561 tcaaacaaat gtatcatact gtcaacttga tgtttggcga tatcgttaaa gtaactccat
    16621 catctaaagt agttggagat atggcactat ttatggtcca aaatgatctt acagaagaag
    16681 atatttatga aaaaggcgaa acactaagtt tccctgaatc tgttgtgact ttcttccaag
    16741 gagaactagg gcaacccgtt ggcggatttc ctaaaaaatt gcaaaagatt attcttaaag
    16801 gcagacctgc attgaatgaa cgtccaggtc ttttggctga atcagtcgac ttcaacgaag
    16861 taaaaaaaga attggcagaa aaaattggct atgaaccaaa acaagacgaa gtattaagct
    16921 atttgatgta tccgcaagtc tttttggact atcaaaaagc atataatcaa tttggcgatg
    16981 ttacattact ggacacacca acatttttcc aaggtatacg tttgggtgaa acaatcaatg
    17041 tacaaatcga acgcggaaaa acgcttatca ttcgtttaga tgaaatcgga gaacccgata
    17101 tcgaagggaa tcgcgtactg ttcttcaatt tgaatggaca aagacgtgaa atcactatca
    17161 aagataattc gatcatcagt acggtccaaa cccgattgaa agctgaaccg acaaaccgag
    17221 aacaaattgg agcaacgatg tctggttctg ttttggatgt attagtgaaa aaaggcgata
    17281 acgttaaaaa aggtgatacg ttgatgatta ctgaagcgat gaaaatggaa acggccatcg
    17341 aagcacgttt tgacggagaa gtcgcacatg tatatgtgtc ttcaggagac actatttcgt
    17401 ctggtgacct tttgattgaa gtgactgaga aataataagc gaaaggtggg gaaacatgaa
    17461 aagactgggt ttgttttggc tgattctgct attagttatt gtggcattct acatggaacc
    17521 agtcttgttt ccgccaaaac ttgaagtgaa ggaaaactct gatcaacaaa tatcaaacca
    17581 aatgacaacg tggaaatacc aggagcttaa agcaactggt ttttctactt atatcggaaa
    17641 accgatcgat cagctggaaa aggattttgg ccaagcctat gatcgattaa ctagcggatt
    17701 tggttttgaa acaagatatt atgaaaataa agctagtcat ctcacatttg aagcgaacat
    17761 ccaagacagc agagtcacaa ctgttaaagt actgcaaaca gggcctgctg atatcgcgcc
    17821 gttttattta gggatgacga tgcaagatct tacgaaaatc actactatct atactaattt
    17881 cacttttgag taccatgata cagaagttgg aatcgaacta atggaagagg atatgaatta
    17941 tcgtccgcta attgcttttg ataacgacac ttttgctatt ttattttttg atcaaacaac
    18001 aaacggccta ttttcagttg tgtatttaga taaagatagt cttttgaaac tattgccata
    18061 tcaagtgttt ggtgaaggcc ttccacatta tcaagcagat aaatcggctg attgggaatc
    18121 aatcaatcgc gttaaagaac gaaaaagtac gactttatta aatatgctta gaagagaaga
    18181 cgaacttccc atatacaatc aaacacttgc ctttcaaaac cacagtcagc tgctactaca
    18241 tgattttttg acaaggcctg aggaaatatt gtcagaggaa cgtatggctg attggcaaaa
    18301 atcgctaggc agtgctcaaa cgacagtgaa attctcactg acgaatgatg aattggagaa
    18361 gttaatcagt aaacaaaaat tagaaaatac tagtgggcta tttattcatc cggcgattga
    18421 cgctactttt tcgtttttat attggtacag cgatccttac aaccatgacc gtttcatgga
    18481 cccgggaacg gattctgtag gcattgcttt ttctaaagaa aatatgttag tcttattgca
    18541 agaagaaaac ggagaaagta gtgatagcag tgatcgttaa cgaagagctg tttcaactgg
    18601 aggatcaatg cctccaagtc gctgaaatga taaaaaagag taaaacgatg gcttcttatc
    18661 ttgaacataa acagtcaatg gaagaatctg caaaagtttg ccagttgaaa gaagcgttct
    18721 tgtctaagaa agaagcattt gaaaatgtag cggcatatgg tgagtatgca cctgattatc
    18781 gtgaaaaaaa acgagctgtt cgaaaagcaa aaagacagct tgatatggat gagcatgttg
    18841 cagctttccg atatagtgaa acacagctgc aaagtctgtt ggatcaaatt gtccaagtac
    18901 ttgccgaaga agtttctaat gaaatcaaag tagatgcagg tagcccgttt tttgaaacga
    18961 aaaaacactt tggatgcgga ggtaattgtc atgcaattag acaatagtga atttgaaata
    19021 acaaaacgac gcgggctgat cgtatgggtc tacagcttaa aacaattaaa gaatctgaaa
    19081 aagttcggct tgttgcatta tgtctcaaga agaatgaaat atgtcgtgct ttacttaaat
    19141 gaagagacat tggaagaaac agaagaacga atccgtaaat tacattttgt tcgaaacgta
    19201 gaacgttctt accgaccgga tatcgaaatg aattttgccg aaaaaatagg aaacaaaaca
    19261 gtattaaaag acgaaggttt cgaaattgaa gagctaaata cagaaatccg attagctgaa
    19321 catctttaaa aatctcttat gagcagtttt taaataaaaa ataacttgga taacgatcga
    19381 tttttgatca ttgtccaagt atttttttgg tatactagta ccagtaccat ttctaaggag
    19441 tgagtagatg cggataatat caggaaatta tggcgggcgc cgtttaaaaa gtttagcagg
    19501 ggcgaacacc agaccaacta cagataaagt aaaagaatcc atattcaata tgattggacc
    19561 atattttgat ggagagacag tattggatct gtttgcagga agcggtggtt tagctatcga
    19621 agcagtatct agaggctgca gtcatgcggt atgcgtagac aaaaattacc aagcgctaaa
    19681 aatcatcaaa gaaaacatcg aaattacgaa agaaccagag aaatttacca caataaaact
    19741 tgatgcggac aaagcaatcg aacggctagc agcggagaaa caacaattcg actacttgtt
    19801 tcttgatccg ccatatgcaa aacaaaaaat aatcgatcaa atccataaaa tggaagaact
    19861 gggacttttt tctaaaaccg cagttatcgt atgcgaaacg gataaaacag tcgaattgcc
    19921 agaaactgtg gctggattcc atcaaataag aaaacagatt tatggcataa cggccgtaac
    19981 tatctataga aaagagggaa atcaatgaaa cgtgcattat tcccaggaag ttttgatcct
    20041 tttacaaaag gtcacttaga tacggtggaa cgtgcggcta aattattcga tgaggtagta
    20101 attggtgttt ttatcaatac ttcaaagaaa agtttgtttc ccccagaaga aagaatgaca
    20161 ttgatcacaa aagctgtttc tcatcttcct aatgtaaaag tcatgcatca agaaaatcaa
    20221 ttgacggtag aaacagcaaa agagattggt gcagatgcgt tgatcagagg catacgaagt
    20281 atcaaagact ttgaatatga acgagagatt gctcagatga atcatcatct atatgatgaa
    20341 ttggaaactg tcttcttatt agcaaaacca gaatatagtc acgtgagttc cagtatttta
    20401 aaagaagtac tgcactttgg cggagatgtg agcagctact taccgccagt gatcaacgaa
    20461 gctttagctg gaaagcgtga atcaaatgaa agctaaacaa tggttgaaaa cagtactgat
    20521 tatcatattt ggaatgttga tcattggatt tgtagtagtt cccttgccgt attatgtaga
    20581 atcaccggga gccacgatcg atctgaaaga actaattacg gtcaatgata aggaagataa
    20641 aggttctggg tctttctctc ttacctctgt tggtatcagg caagctacag gtttcttagc
    20701 tttaaaagct aaaatgaccc cttttgaaga attgatcagt gaagaagaat tgactggtgg
    20761 ggcgacaaat gaagaatata atcaaatgca acagtattat atggattctt cccaaaatgc
    20821 agcaatcgaa caagcgttaa aacttgcaga caagccttat aaaatggaat tcaaaggcgt
    20881 atatgtcatg agtgtagaga aaacatcgaa tttctttggc aagctttcag ttggagatac
    20941 agtaacaaaa gtagacggga aaagctttca aagtacagaa gcatttatgg attatgtaaa
    21001 aagccaaaaa gttggacaaa caatcgaaat cagttatttg cataatggtg aagaaaaaac
    21061 agcttctggt gatctgatcg agttaccaac agataaaaag gcaggaatag gtatcacgct
    21121 tactgaccat accgagatcg aatcagatac agatgttcgt attaattctg gctctatcgg
    21181 tgggccatca gcgggattga tgttcacttt agaaatctat gaacaagtca ctggtaaaaa
    21241 cttgcgacat ggtaagcaaa ttgcaggaac tggaacgatc aacagtgaag gagaagttgg
    21301 ccgaatcgga ggaatcgata aaaaagtggc aagtgcggat aaagctggcg tagagatttt
    21361 ctttgcacca gatgatacga tttcagacga tgttaagaaa gaatatcctg aaataaaaac
    21421 caactacgaa gaagcaaaag ctgccgctaa aaaattgaat tcctcaatga aaatcgtacc
    21481 agtaaaaaca gtacaagaag cgcttgacta tctagagaaa atgaaatgaa actaaataat
    21541 taaagagggg ttgtgacacg agttctgtca caacccctct ttttcgtcaa aa
//
LOCUS       DAYNVV010000047        21279 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.047, whole genome shotgun sequence.
ACCESSION   DAYNVV010000047 DAYNVV010000000
VERSION     DAYNVV010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21279
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.047"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            132..506
                     /locus_tag="ACGXWR_001967"
     CDS             132..506
                     /locus_tag="ACGXWR_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFK0803519.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(620..1249)
                     /locus_tag="ACGXWR_001968"
     CDS             complement(620..1249)
                     /locus_tag="ACGXWR_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFK0803520.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1383..1455)
                     /locus_tag="ACGXWR_001969"
     tRNA            complement(1383..1455)
                     /locus_tag="ACGXWR_001969"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1420..1422),aa:Thr,seq:ggt)
     gene            1669..1742
                     /locus_tag="ACGXWR_001970"
     tRNA            1669..1742
                     /locus_tag="ACGXWR_001970"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1703..1705,aa:Asn,seq:gtt)
     gene            complement(1880..2044)
                     /locus_tag="ACGXWR_001971"
     CDS             complement(1880..2044)
                     /locus_tag="ACGXWR_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803521.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2339..3667
                     /locus_tag="ACGXWR_001972"
     CDS             2339..3667
                     /locus_tag="ACGXWR_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HFK0803522.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3869..4702
                     /locus_tag="ACGXWR_001973"
     CDS             3869..4702
                     /locus_tag="ACGXWR_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HFK0803523.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4718..5455
                     /locus_tag="ACGXWR_001974"
     CDS             4718..5455
                     /locus_tag="ACGXWR_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HFK0803524.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5610..6578)
                     /locus_tag="ACGXWR_001975"
     CDS             complement(5610..6578)
                     /locus_tag="ACGXWR_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HFK0803525.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6810..7643
                     /locus_tag="ACGXWR_001976"
     CDS             6810..7643
                     /locus_tag="ACGXWR_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HFK0803526.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7677..8516
                     /locus_tag="ACGXWR_001977"
     CDS             7677..8516
                     /locus_tag="ACGXWR_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFK0803527.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8542..9102
                     /locus_tag="ACGXWR_001978"
     CDS             8542..9102
                     /locus_tag="ACGXWR_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFK0803528.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9301..11022
                     /locus_tag="ACGXWR_001979"
     CDS             9301..11022
                     /locus_tag="ACGXWR_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HFK0803529.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11187..12329
                     /locus_tag="ACGXWR_001980"
     CDS             11187..12329
                     /locus_tag="ACGXWR_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFK0803530.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12345..13556
                     /gene="thiI"
                     /locus_tag="ACGXWR_001981"
     CDS             12345..13556
                     /gene="thiI"
                     /locus_tag="ACGXWR_001981"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HFK0803531.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14129..14776
                     /locus_tag="ACGXWR_001982"
     CDS             14129..14776
                     /locus_tag="ACGXWR_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFK0803532.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14905..15121
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15169..17814
                     /locus_tag="ACGXWR_001983"
     CDS             15169..17814
                     /locus_tag="ACGXWR_001983"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HFK0803533.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18124..19437
                     /locus_tag="ACGXWR_001984"
     CDS             18124..19437
                     /locus_tag="ACGXWR_001984"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HFK0803534.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19427..20080
                     /locus_tag="ACGXWR_001985"
     CDS             19427..20080
                     /locus_tag="ACGXWR_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFK0803535.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20135..20827
                     /gene="radC"
                     /locus_tag="ACGXWR_001986"
     CDS             20135..20827
                     /gene="radC"
                     /locus_tag="ACGXWR_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFK0803536.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20977..21177
                     /locus_tag="ACGXWR_001987"
     CDS             20977..21177
                     /locus_tag="ACGXWR_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFK0803537.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
BASE COUNT         7183 a         3551 c         4445 g         6100 t
ORIGIN      
        1 tctacactct gagatgtaag aaatatcata agatatttct tacatctttt tgttttgagc
       61 aggactttag ataattttat taatatatgc tagcatgctt ttgtaagaaa aagaaagagg
      121 gcgtattagt tatgtatctt aaaattacgg aacaagcaca agaaagatta caaaaatata
      181 ttgatgaagg cgcaacagtt atattggatt tagatgatgg cgttggggaa tattctaaaa
      241 tgggtgtttg ctctttagat actagttttc gtttacttct tcttgataaa gaacagagaa
      301 aaaatgatta taaactccaa ttagatagtg atattgggga tgtttatata aaagattatt
      361 caaaaatgta catggatgaa catatgaccc tttctttaga tccacgtcta ggtgtattta
      421 ctcttgaaag cccaagtggt tctttagaca gtcatgttca attagtagat ctacgaccag
      481 aaaaattctc tggaataaaa caataacttt ctctctattg tccataaaac tagtctcaat
      541 caagctgtat tgaaaaaaca agacaacatt cttaccatgg taaataaaaa gacgacacat
      601 tttgtcgtct ttttttaaat taactatttt cgataaaaga tcgcatagct tgtgccatta
      661 tttctggctt ttctctattc aattcatgtt ttccgttttt aataaagagt agccggccat
      721 tcgttgaaag tttatataaa cgttttgctg ctggtttatt cgcatgatct ttggtaccgc
      781 ataaaatcaa tttaggaagt cgtgatgtac gaagctgttt tttgcagtct aatgtttcaa
      841 gtgaacgaag tagggtaagg gtttgttttt tagatagacc taatttttca aatatcttag
      901 aaggtacgca gtaaaaataa atattctgga aagtaagcaa taagcgatta ggagactcaa
      961 attgtggagc gactaaaaca acctttttta aatatggaga aggagttgca agatagttta
     1021 aagcaataac agcgcctaaa gataatccac ataaaataaa aggttccttt atctgattca
     1081 attgtacttc gatgtatttg gttaagtcgt ctaaagtagc agtgtctgtg ctgtttaaat
     1141 gattgaacaa tgaaagactt ttgcaagaat aactattggg tagataagag attacatctt
     1201 tccatgattg ttcgtcttgg cctagaccat gcaaaaaaac aattttcata ttgctctcct
     1261 ttttatagtt atcatataga ctttctttgt actattaaaa tataaacatt catttcttac
     1321 gtcataaaat aaaaaaacag cgcagacaca ttgttaaacc aacatgttgc actgtttaag
     1381 gaagccactt gccgggcttg aaccggcgac ctcttcctta ccatggaagc gctctaccag
     1441 ctgagctaaa gcggcattat cattaataca aataatagga taacgaatat taatgtattt
     1501 gtcaacagaa ttttttcgaa aaaatgtgtt tctctaatag gaaaacagat tttagaaaaa
     1561 ataaaaataa caaaaaatgc gaacggtttc tttgataata taataaaaaa attcaaaaaa
     1621 agtattgcgt tatttagaag aaattgatat tatattcatg tacttgattc cggcatagct
     1681 cagttggtag tagcgcatga ctgttaatca tgatgtcgta ggttcgagtc ctactgccgg
     1741 agtaaataaa gcttatgcaa agaaaaagaa atccaatcac ttgggtttct ttttctttta
     1801 ttattatgat gaatcaagct ttctgttttt gtcacgtatg ttgtaatctt tacgaaagag
     1861 tagagttggc tactcataat caaccatact tcccatcatc gctaaatacg aaataaatca
     1921 gcattcctac accaatcaaa gcacaagctg caccaagaaa agggatgaca ttcccaaagt
     1981 tatctgtatt cataagtatg ccaccaccca caaacaaaaa gccgccagca atcaggtttt
     2041 tcattttatt catctccttt cttacgttat agtatttcct tctttcaatg agtattttga
     2101 aagctatctt attgtatgat gttcttctag gcctcttctt tattatacag gccattttcg
     2161 ttatctcata gaaatattcc tttttatctg aaaactattg tataccgtat gacatttttc
     2221 ttcatgaagt tgtaagtata ttctcattca aatgaaaatt tcatcataga agagattgta
     2281 tttctaaatt cttaagagta aaatacgaag tataacttgg atttggaagg atgattggat
     2341 gaaagctatt acgcctgata tgacaacaaa atttaacaaa cagtttcaag caaatatcaa
     2401 acagcaggca ttgcagcggg cagttgtgaa gaacggaatt actgcttctg ctgaaaatgt
     2461 ttcagcacat gtggagaata caccggtatt ttctatagat ttggctacgg ggaaagtggc
     2521 taatcaaatg caatcggggc gttgctggat gtttgctgca ctgaacacat tccgtcataa
     2581 gatgctgaat caattccatt taaaagagtt tgaattatca caaaattaca cttttttctg
     2641 ggataaatat gaaaaggcaa attatttcta tgaaaacatc attgcaacag gaaaagaggc
     2701 aatcgatagc cggaaagtag ctttcttact cgctactcct caacaagatg gcggccaatg
     2761 ggatatgatc gtttcattat tccaaaaata tggcgttgtg cctaaatcgg tgatgccgga
     2821 aagtgcgaat agttcaaatt ctcgagattt gaataactac ttgaacaaat tactgcgtaa
     2881 agatgcagta gtgttacgga aaatggttgc tcaaggagaa acattagacg ctattgaaga
     2941 aaagaaagaa gaaatgctag aaagcattta taacttctta gctatctcat taggaacacc
     3001 tccaaaagaa ttcgattttg agtaccgcga tgaagaaaag aactatcatc ttgaccgagg
     3061 actgacacca caaatttttt atgataaata catcggtgta aaattagatg attatgttag
     3121 cgtgatcaat gcaccaacaa aagacaaacc attcaatcgt tcttatacag tagagatgct
     3181 aggaaatgtc gttggcggga aagaagtcaa atatctgaat gttgatatgg aaactttcaa
     3241 aaaattagcg attgctcagc ttgaagaagg agaatctgtt tggtttggtt gtgatgtagg
     3301 tcaatcttct actagaacta gtggcatcat ggccttagat gcttattcaa tggatgatct
     3361 atttgatacg gattttacaa tgactaaagc tgaacgttta gattttggag aaagtctgat
     3421 gacccatgcg atggtattga ccggtgttga cttagtagac gggcaatcaa caaaatggaa
     3481 agtcgaaaat agctggggcg aaaaagttgg aaagaatggc ttctttgtta tgagtgatgc
     3541 ctggatggac gaatatacgt accaaatcgt tgtaagaaaa gatttattga cgaaagagca
     3601 attaaatgcg ttcaatgaag aaccaattgt tctatctccg tgggatccaa tgggtgcttt
     3661 agcatagacg agtatttcaa tgaagagtat gtagtaaaga taaaaagagc tggcttaagc
     3721 cagctctttt tatctttaaa gtccattccc tgttttttat ggtccctgtg ctataattct
     3781 aaataaagga taaggattgg aaataatcct tttatcatta aaaatatgat gacgaagtag
     3841 aataaaattg ggagtagggg ggaaagtcat ggatatccaa actgttttat ctgatctgaa
     3901 attaaatggt aaagtgattc cagttgttgg tggcgatgtt aatcagacct atcgtataaa
     3961 aaccgaacat cgtgcttatt ttttaaaaat ccatccgaat gtaaaaaaag gattttttga
     4021 agcagaagta gacggattaa aagaactgtc agcattcgta cgtgtaccgg atacgtatat
     4081 gctaggtgaa acaagtgaag gcgcttattt gttaatggaa tggatcgagc cgggaaaagg
     4141 ggatcaacga gatcttgctg cagctttagc taatctccat cagcaaacag cgccacaatt
     4201 tggttttcgt aaagataact atttgggtac acttgttcag aaaaattctt ttgaagaaga
     4261 ttggtggact tttttcttta aagatcggct tgaatcccag atttctttgg cagaagaaac
     4321 gaatcgatgg aatgtacagc gtcaagaaaa gtatctgcga tttaaagaac gtgtattgaa
     4381 atcggttgaa ccaaaaaaga tcactccacg cctcttgcac ggagacctgt ggagtggtaa
     4441 tgtgttcttt gaccagcaag ggcatccagt ttttgtcgac ccagctgttt cttatgggaa
     4501 tcgggaacaa gatattgcaa tgagccagtt attcggtggt ttccgaccgg aatttttaga
     4561 tgcttatcaa actatatttc cattagaaaa gggatggaaa gaccgactgc cgatttacca
     4621 gttatattat cttttggcac atttgaatat gtttggagaa agttacggtt cccaagtaga
     4681 tcaattacta gaaaattttt aagaggaggg cgtgtttttg gcaaaaaaat ataccaaaaa
     4741 gcatgaagtt tcatattatg agtgtgacat caaccaaacg atgacatttc cttcgatgtt
     4801 aggagtagtt atcaaaacgt ctgaagatca aagcgaccag ttgggaagag gcagtgaatt
     4861 cgtcaatagc tttggactta cttgggtcat cacgaattat tccatggaga ttaatcgtct
     4921 ccctagagtc ggtgaagtaa tctcagtaac gactcaagcc atggagtaca ataagttttt
     4981 ctgttatcgg aacttctgga tccatgatga agatgggaaa gaattagtca aaatagaatc
     5041 tgttttcgta ttgatggatt ttgtgaatcg aaaaatgagc agtgttaatg aagagatcat
     5101 tgctcctttt gagagtgaga agatcaagaa aatcaagcgt caggaaaaaa ttgaaaagat
     5161 tgattcgggc ttcatgttgc catatcgtgt tcgtttttat gatatcgata gtaatcagca
     5221 tgttaataat gcgatgtatt ttaattggat cattgacgta ttaggatatg actttttgac
     5281 tacgcatgtt ccagaaaaag taattattcg atttgataaa gaagtagagt acgggaatga
     5341 gatcgaaagc cattttgaac aaatccctat cgaaaatggt gtcaaaacaa aacatgaaat
     5401 ccgaatgcaa gaacagctgt attgtgaagc aaatattata tggaaaaata aataaaaaag
     5461 aggttgtgac agaagggggc aacttcaaga aataagaaga aatttacgaa aattgtttct
     5521 caaatttttg taaattttcg acttagtttt cgaagaagct atttttgtca cagcctctct
     5581 ttttaagttt agctattaga taatgatgtt tagttttgga taaacgaaat caattcttca
     5641 cccgacaaac catagtttac agcaatcaat agttttaaac gtgctttttg actattaata
     5701 ctgttacaga aaataatccc cattttttct agttcttttc ccccgccttc ataatcataa
     5761 acaggctctg cgattccatt gaaacaacga gaaacaagta ctacagggat tttttggaca
     5821 agaagctttt ccaaagcagc taaggcttgt ggagggagat tccccgcacc taaagcttcg
     5881 attaccaaac cgtctacttt cgtatgggcg atggcttcca ataagtcccc ttgcatccca
     5941 gcatatgctt taacgatcgg gatagtccca tctacagcgg aaatgtccag tcgctttgtt
     6001 tctaaaagtt cctgcaagaa taaaattcga ttcttagtta ctaagccgat gggacccaat
     6061 gtaggtgttc ggaaagtagc aacatttgtg gtatgggtct ttgtcacgta gcgtgcagaa
     6121 tggatctcat cgttcatgac caccaaaacc cccttatcta gcgcttcttc acaacttgcg
     6181 acacgaatcg cactttcaaa attataaagg ccgtcacttc caagttcatt acttgaacgc
     6241 attgccccag tcaaaacaat tggtaatttg ttgccaatcg ttgtatcaag aaaaaaagca
     6301 gtttcttcta atgtatctgt accgtgtgtg atcaccactc cggatatacc tgatgcataa
     6361 gcggacaaga tacgttcttt taataccaac atgtgagaag gcatgatgtg tggtgaggga
     6421 agattgaaga tatcttcaac taataattct acatgcttgg ggattgtgat ttctgcatct
     6481 aataatgggt ttgccacatc aggactaaca ccgcccgtga gcatgttttc tttcatggcg
     6541 atcgttccgc cggtgtgtag tacaagtatt tttttcattt tacagacttc cttacgaata
     6601 attttgcata gccgttaaat cttattgtat actatataaa agagttttgc tatcagtgaa
     6661 gaataacgaa tagcctaact tatcataaaa aagctgacct tattaaaatg gaaaagactc
     6721 aaccttgacc tcctaataca atggagtatc tggttgagtt tcttttacaa gaaagcagcc
     6781 aaggaaatca atcacgaagg tggccggaaa tgatcagaat cggattaaca tcgtttaaag
     6841 aacatgacaa attaactggt aaaaagaata acactcttta tgaatatgca gggtttctac
     6901 ccttagtgga attagatact gcctattatg gaattccccg aaagtcctca gttgagaatt
     6961 ggataagtga agtacctgaa tcatttcgct ttgtagtcaa agtctatcaa ggaatcagcg
     7021 gtcaaggaga ctggaagcct tattatcaga ccgaagaaga gatgattgcg cattttttag
     7081 atgttatgtc gccaatggta gatgctggaa agatgttttg ctttttagtc caattcccct
     7141 catcattcaa atgtacgaaa gaaaatgtcc agtacttgcg caaacttaga aagtggtttg
     7201 agggttatcc tgtttctata gaattgcggg attattcttg gtacagcgat gaatttcttg
     7261 aacgtacaag aaactttatg tctagagccg ctttttcttt agccatcatc gatgagccac
     7321 agttgctgaa tacaacgatt ccttttgatc catttgtcac caatccgaac tttgctcttt
     7381 ttcgattcca tggtaggaat gcgcaaggat ggcaagcaaa tgataaagag tggcgtaaaa
     7441 aaagaacgtt atatcgttat tcagaaaaag aactgcaaga actagcacat gaagtcaaag
     7501 tagttgattc taagacaaaa gaggtaggtg tgatttttaa taataattct ggtggtgatg
     7561 cggctgaaaa tgcattagca ctgcaaaaaa tattaaatat caagccagat ggactcaatc
     7621 caacccaaat ggatctgttt taagggctta ttttattcaa gaaaggggcg aagtctatga
     7681 tcaaagctat tttttttgat attgacggaa cattggtcac caatcgttca aaagcgttgg
     7741 aatcaacaaa acaagcaatt gaatatgctc ggaaaaacgg cattttatgc ggtgtagcaa
     7801 cggggcgcag cccagtaaag atcaaagaaa tcattgatga attggaatta gatatgtatg
     7861 tcgtgtataa tggtcaactg gtttttactg cagatcgcac gattatcgac cacccttttg
     7921 aacaaaaagt attggaacat attgttgaat ttgcagatga gaaccatcga caaatcgttt
     7981 ttggtgcgag aaatcggtta gatggatcaa cgacgatgct attaggacaa tcgattttta
     8041 tcaagcgact agtcagcttt ttaccgcgta aattcccggt acgtctgatg aaaaaaatcc
     8101 tccaggtttt tagccctcac cgacaaaagg atcgttatga aacgttagag atattaaaag
     8161 aaccaattta tcaatgtata ttgctcagtc cggagtcaga acagaaaaag ttagaacatc
     8221 gctttcccga gtgtacgttt cagcgttcaa atacgtatac tgtagatatc atcccaaaag
     8281 gtggttcaaa attactaggc atccaagctt tcgcaaatgc tgtcgaaatt gaaatggaag
     8341 aaattatggc attcggcgat cattacaatg atatcgagat gctgaaaggt gtaggaattg
     8401 gagtggccat ggggaatgct cagatcgaag taaaacatgc tgcagacttt gtgactcaat
     8461 caaatgaaga agatgggata tacgaaggac tgaaacactt cggtctgatt tattagtcaa
     8521 tgaaagaagg aaaaaatcag tatggaagca gagacacctt ttcaaaaagt agaaacattc
     8581 cacaaaactt ttgatccaag aagaccagag atacccacgg cttttacaga aaatgaagct
     8641 catacacgtg ctgcgttcaa aatagaagaa cttgttgaat ttgttgcagc tacttcacct
     8701 aataaagaac aactgcatga agctgttatg ctgctgcacg aagcattaga taaagcagaa
     8761 gaaaaaatac ttggtaaaac acagtgggga agtgatccgc tggttgaaca agtagatgca
     8821 ctgacagata tcctttactt tacttatggt tctttttcat tactaggaat agtgcctgat
     8881 cgaatattcg aaatcgtcca tcaggcaaat atggggaaat tatttccaga tggaaaacct
     8941 cattatgacc ctgtaacaaa taaagtgttg aaacctgaaa actggcagat ggaatatgct
     9001 ccagaaccta aaatcgcggc agaaatccaa cgtcagattc aagaagcgat tgctaagaag
     9061 aaatccgctg atataggcat gtgcacaaat gaaaaagagt gatcagagtt tcactatttt
     9121 tgttatcttt atacgatgga aaaacaaaag attttcgttt aagttagtga atgcatgaaa
     9181 atagtatgct ataatctaga atagatgtct tttgcacgag agacgtatta tttggattta
     9241 tgccaagcag aacgccatct gttgcataaa agatgcatac tgaaaacgga ggaaccataa
     9301 atgggaaata atgttatcat cggaatcgtc attgcaatca ttatagtcgc cattgtcgtc
     9361 tttttggtta gttacttgat gaagaaaaaa aaccaagatc gattggatgc cttagaaaaa
     9421 cgcaaggaag aattatttga cttgccagtg attgaagaag tcgatgatgt taaaaaaatg
     9481 catctggttg ggcaaagcca aaataccttt cgtgaatgga gtcaaaaatg gaatgacata
     9541 tctacttcct cgttcgctga actagaaagt caaattttcg aagtggaaaa cctcaatgaa
     9601 agttttcggt tcttaaaagg aaaaaaagca gttgttgaag cagaagctac aatggaccaa
     9661 atggagaaac aagtgacgga aatccgtgaa ggtctaaagg aattgcggga aacggaagaa
     9721 cgcaactcac tagctgttca gcaggcactt gacgtctatg aagaactgaa agaaaaagtc
     9781 agagaagacg agcatgaata cggaccagct ctttttgaat tgcaaaaaca gatcaaagtg
     9841 atcgaaaaag aatttacgca gtttgtgact ttaaacactt ctggagaccc tgttgaagcc
     9901 cgcgaggttt tggataaagc agaaaaacat acgtatgaag tggaagctct gatgaaaaaa
     9961 attccaccgc tgtatgagga gctccatacc actttccctg aacaacttga agaaatcagt
    10021 gatacttacg agaaattgat ggaagaacaa tatgtattcc cagaagaaga tcttgctgaa
    10081 gatatcgcaa aagtaagtcg aagaattgaa aattcattag ccaatcttga aaaaacagaa
    10141 gttgaaacgg tcgaatttga aaaccgtgaa acagctgatt tgattgattc gttatatgat
    10201 atcttagaac gggaaatgga agctcagaga tatgtaaaaa ctaaccaatc aacgattgca
    10261 gagtatatca aacatacaac aaagaataac cgtcaattat tgattgagct ggatcacaca
    10321 tctcaaagct atacattgaa ccacaatgaa attggccgtg tacgaggttt ccaaaccgaa
    10381 gtggaagaaa tggaacgtca aaatgaacag atgattccac agatccgtca acacgaaatt
    10441 ccttattcag aagtgcgcac gttctataaa acagtcttca aagtcttaga agatatcgaa
    10501 aagcaacaag tagagatcga cgactcatta catgaattga gaaaaggcga aaaagaagcg
    10561 caagaaaaga tcgatacatt cgaattcaaa ttgcgcagtt tgaaacgttt tgtagaaaaa
    10621 caacgtttgc ctggcttgcc gaatgattac ctagaattct tttttgttgc tactgaccgt
    10681 attgaagaac taagtgttgt cttgaataaa attcgagtaa acatggaaga ggtcaatcgt
    10741 ttagttgctc tatgtgaaga agatctagaa ttattagata agaagacaca tgatttagta
    10801 gatgcagcag cattaacgga gcaaatgctc caatatgcaa atcgttatcg tcatacacac
    10861 gaagaagtga gagaagcaat tgataaaagc tactatttat tcaataaaga atatcactat
    10921 caagaagcat tagacgaaat cggtacagca ttagagcgag tagaacctgg tgctttcaaa
    10981 cgcatcgaag atttttattt taatcatcca gacttagtat aaagcaaaaa agttagtaaa
    11041 ccagcaagag caagacggat tattgtcttg ttcttgtctt tttttgtata tttgaaaatt
    11101 gaaacaagtg aaaatttcac ctgctcttga aagcaccttg gacaaccgtt ataatagaaa
    11161 agaatttcaa aaaagagggg tttcttatga tatattttga taacagtgca acaaccccaa
    11221 tctttccgca aagcttagat gcatatgtaa aaaccagtca gcggattatt gggaatccat
    11281 caagcttgca tgatttaggc aatcaagcta accggttgtt gcagcaagca agaaagcaga
    11341 tcgctgattt gatccatgta gaaccagaag aaatctattt tacttcaggc ggaacagaag
    11401 gagataactg ggtattaaaa ggaacgatga tcgaaaaaag agaatatggg aatcatatga
    11461 tcatttcagg agtcgaacat ccggccgtca gcgagacagc agaacaatta aaagaattag
    11521 gaatcgaagt aagtatcgcc ccagtggata aacgcggatt tgtacgtgtc gacgaattga
    11581 aagaattaat aagaaaagag acagtattag tctctgttat ggctgtgaat aatgaagtag
    11641 gatcgattca gcccatccag gaaatcagtg atcttttgga tgattttcct aaaattcatt
    11701 tccatgtaga tgctgttcag gcgattggaa aagtaccatt ctcgcaatgg ttgacagaaa
    11761 gagttgattt tgcaacattt tcagctcata aattccatgg cccacgggga actggtttca
    11821 tttattggaa aaagggtcgt cgtttagcac cattactgac aggtggaggg caagaaagaa
    11881 atcagcgaag tgggacagaa aatgttccag gtattgtggc tatggttaaa gctttacgtt
    11941 tatcattaga gataaaggaa caaaaacctg agcagacaca acgcttaaaa gtagctctaa
    12001 tcaatgcgtt gaagacgtat gagaaagtga cgattttttc agaaggaact gactatgcac
    12061 cgcatatttt atgttttgct ctaaaaggaa ttcgcggcga agttctcgtc catgccttag
    12121 aagaaaaaca aatatttgtt tctactacta gtgcctgctc ctcacgtaaa catatggcaa
    12181 gcagtacatt gcacgcaatg catgtaccaa atgatctggc tacatctgct gttcgaatca
    12241 gcttagatga aaacaattcg cttgcagaag tcgagcaatt tatgattatt ttcaagcagc
    12301 tttataagaa attttctgca atcaattaaa agaggagtgt tcttgtgaaa tacagtgaaa
    12361 ttatggtccg ttatggggaa ctttcgacaa aaggaaagaa tcgaaaaagc tttatcatgc
    12421 aactagcaca aaatgtcaga caagctttga aagactttcc agaaatcaaa atccatgctg
    12481 atcgggaccg gatgcatctt ttattgaatg gcgcagacgg gcagctagtt attccaaaac
    12541 tagcaaaaat atttgggatc caaaatttct ctccaagtat tcgtgtagaa aaagatgtcg
    12601 aagttttgaa acaagctgtt caagacatca tgaaagaaat ttatactggg aaagaaacat
    12661 ttaaaattat cgctaaaaga agcgatcacc aatttgaatt gacaagtaat gaattgaatc
    12721 aaacattagg taatgctgtt tttgatattt tcccgcatat ccaagttcaa atgcgtcaac
    12781 cagatattcc attacgtgta gagattcggc gtgatggcgc ttatctatcg tatgaaacga
    12841 tcaagggagc tggaggattg cccgtaggaa caagcggaaa aggaatgctt atgctttctg
    12901 gggggattga ttctcctgta gcagggtact ttgccatgaa gcggggagtg gaaattgaag
    12961 ctgttcattt tgctagtccg ccgtatacaa gtgaacaagc actgcaaaaa gcaaaagatc
    13021 taacagccaa actagcacct tatgtgggaa cgatccattt tatcgaagtg ccatttaccg
    13081 agattcaaga agaaatcaaa aagtcagtgc cacaaggata ttggatgaca attactcgtc
    13141 gaatgatgtt gcgtttgacc gatgaaattc gccgtattcg tcatggttta gtcattttga
    13201 atggtgaatc attaggtcaa gtggcttcac aaactttgca aagtatggtg gctatcaatg
    13261 aagtaacgaa tacgccaatc attcggcctg tagcgacaat ggataaactt gaaatcattg
    13321 aagtagcaga acagatcgat acatttaatc tttctatcca gccttttgaa gattgctgta
    13381 cgatttttgc tcctccacag ccaaaaacac gccctcaact ggaaaaggtc catcaatatg
    13441 aagagcgttt agcaatagat gaaatgatcc aacgagcact agctggcttg aagatggaag
    13501 agatacaagc agaatcgtct aatgaaaaaa ctgaagaatt ttcagaattg ctataagagg
    13561 ttatgaaaat agtgttttga ccagagtatt agagaaacaa aacgaaaaaa tagctccatg
    13621 tattttaccg tttttgaact aatgtcgaag attagctgat tgaataccat ttatcaagaa
    13681 gttatggaaa agccggttct tttttactaa ctgaaaaata aaattttatt tagagatcaa
    13741 gctacagttg ataaatgata taaaaaagag aatttcccat gaaatagcga ggttgtgaca
    13801 gaagtgggca gcttcaagaa ataagaagga atttacgaaa attgcttttc aaatttttgt
    13861 gaaatttcgg cttatttttc gaagaagtta cttctggaac accgtgtatc agaggttgcg
    13921 aaaaagctgc cctgcatcaa gtaataagaa cagccaaaca aaaatagttc ctcatatttt
    13981 acgtttggtt gagcttatta ccgcagatgc aagcttttga acaccgtttt atttgtctca
    14041 cacccttttc cttcctactt gtaaccttgc tcccgtgtta gaaacatgtt acactaaata
    14101 tgtgaaatta ttaacaagga gcgtcgttat gcgagaaaaa acagatacac tgccaaaagc
    14161 aactgcgaaa agattacctt tatatttacg ctacttgaag atgctggatg actcaggtat
    14221 aagtagaatc aaatcaaatg agttcagcga aatcacccaa attccttctg caacgatccg
    14281 cagagacttc tcgcaattag gcgagctagg cagaagcgga tatggctatg atgtcccttt
    14341 tcttatcgat gtattcaata atatccttaa tactaaagaa gaaaaacgaa tcgcattagt
    14401 aggatatgga aatcttggca aagcattgaa acacaacaat tttagaagaa atgaaaatct
    14461 aaatatcgtg tgcgtctttg ataatgatcc agcactgatc aatcgagtaa ttgatggaga
    14521 aatgatctat ccgattgatc gtttcgcgga gatagccaaa gcaaaaaatg tgacagtagc
    14581 aatctctacg gtaccaagta aatattcaca atctgctatt gatgaaattg tcaaaggaaa
    14641 tgtaaccgct atacttaatt ttgcgcctga cagagtaact gtcccagctt atgtcaatgt
    14701 tcaatacatt gatttgacaa ccgagttgca gacgcttatt tactttgatg agaattactc
    14761 agaagttttt tcttaggaaa atttgagtag gcttattgat cttgcgagaa ctcgtcgtaa
    14821 ttctttcaaa aattttttag tactaaatga agtggttttt tcacgaccac ttgttgacta
    14881 aaaaaaaaaa ccattgtaga atgaagcata acgctgaaca agaggagtaa ctggcacatt
    14941 cattcttaga gagagaacta tctgctgaaa ggttctcaat gacaaccagt gaaggtagct
    15001 tgggagtttc tgtcttgaat ggagtagaga tagacgagtc gtgatcgtta actcacttga
    15061 gaggcaataa tgattgatta ttgcaattta ggtggtaccg cgtaaatcat acgtcctaga
    15121 atacgaaagt attttaggac gttttttagt ttaaaggagg aaaacagcat gacggaagaa
    15181 aataacctat caacaaaata taatccgcaa gaagttgaag ctggacgtta tcagcattgg
    15241 ttagaacaag atttgtttaa accgagcgga gataaaaaag caaaacctta ttcaatcgta
    15301 atcccgcccc caaatgttac tggaaaactt catttagggc atgcttggga tacgaccttg
    15361 caagatatgc tgattcgtca aaagagaatg caaggatatg atactttatg gctgcctggt
    15421 atggaccatg caggaatcgc gacacaagca aaagtagaag cgaagcttag agagcaaggg
    15481 atttctcgtt atgatctagg tcgtgaaaag ttcatcgatc aagtgtggga atggaaagaa
    15541 gagtatgcga gccacatccg cgaacagtgg gctaaaatgg gcttatcttt agattacagt
    15601 agggaacgtt ttacattaga tgatggatta tctgaagcag tacgtaaagt ttttgttacc
    15661 ttatacgaaa aaggtttgat ttatcgtggt gaatatatca tcaactggga tcctcaagca
    15721 cgaacagctc tatctgatat cgaagttatt cataaagata tcgaaggcgc cttttatcat
    15781 atgagctatg aactagcaga tggatcaggc gtagtagaaa ttgcgacaac ccgtccagaa
    15841 acgatgttgg gagatacggc gattgctgtt catccagaag acgagcgtta tcaagcgctc
    15901 atcggcaaaa aagtgattct acctttagtc aataaacaaa tcccaatcat tgcagatgaa
    15961 tatgtagata tggaattcgg gacaggtgta gtaaaaatca ctccagcaca tgatccaaac
    16021 gactttgagg taggtaatcg tcatgatctt ccacgcgtaa atgttatgga tgatgatggt
    16081 acgatgaatg aactagcagg aaaatatgct ggaatggaac gttttgctgc tcgtaaagca
    16141 atcgtgcaag atctgaaaga aatcggtcga ttgattaaaa tcgatacgat gatccacagt
    16201 gtgggtcatt ccgagcggac aggtgtcgtt gttgaacctc ggctgtctac tcaatggttt
    16261 gtaaaaatgg cgccgttagc gaaaaaagcc attgataacc aagaaacaga tcaagcagtg
    16321 gaattcttcc ctccaagatt caatcaaacg tttttacgtt ggatggaaaa tgtccatgat
    16381 tgggtaatct cacgacaatt atggtgggga catcaaattc ctgcatggta tcacaaagaa
    16441 acaggtgaaa tgtatgtagg gatggaagca ccagcggata gtgaaaactg ggtacaagat
    16501 cctgatgttt tagacacttg gtttagttca gctttgtggc ctttctcaac aatgggctgg
    16561 ccagatacgg aaagcgaaga ttataagcga tacttcccta ctagcacttt agtaaccggt
    16621 tatgacatca ttttcttctg ggtaagcaga atgattttcc aaagcttgga atttactggc
    16681 gaacgtccat ttgagaatgt cttgattcat ggattgattc gtgacgaaca agggcggaag
    16741 atgagtaaat cattaggtaa tggaatcgat ccgatggaag taatcgaaaa gtatggagca
    16801 gatgctctcc gctggttctt atcgaatggt tctgcaccag gacaagatgt ccgcttcagc
    16861 tatgaaaaaa tggatgcttc ttggaacttt atcaacaaaa tctggaatgc ttcacgtttc
    16921 gttatcatga atatcgaagg aatgaccgta gaagagatcg atttatctgg agaaaaatca
    16981 gtggctgacc ggtggatcct tactcgtttg aatgaaacga tcgaacgagt aactgagcta
    17041 tttgatcgtt ttgaatttgg tgaagcaggt cgacaactgt ataactttat ctgggatgat
    17101 ttttgtgact ggtacatcga aatgagtaaa gaagtacttt atggagatga tgctgtttca
    17161 aaacaaacca cccgtagcat cttagtccat acacttgatc agatcctacg tttattgcat
    17221 ccaatcatgc cattcgttac agaagaaata tgggaacata ttcctcatca gggaaattct
    17281 ctagtagtgg cagaatatcc tgttgtacgt ccagagtttg atgatgaaac agcttctaaa
    17341 gggatggaag tattgaaaga attgattcga gccgttcgaa atattcgttc agaagtgaat
    17401 acaccattgt ctaaaccaat tacgttgcta attaaaacaa acgatgctaa aatcgatcaa
    17461 tttttagttg aaaatacaag ctatatcgaa cgcttctgta atcccgaaga gttgacgata
    17521 tcaagtgaga tcactgcgcc agatctagcg atgtcagctg ttctgacagg tgcagaaatc
    17581 ttcttgccgt tagcaggatt gatcaatatt gaagaagaaa tcaaacgatt agaaaaagaa
    17641 ctggaaaagt ggacaagcga agtaaaacgt gtccaaggaa aactttctaa tgaacgtttt
    17701 gtttctaacg cgccggaaga agtagtagag gcagagcgtg caaaagaaaa agattattta
    17761 gagaagcaaa cggctgtcaa agaacgaatc gaaagtttgc gtactattca ataagaatag
    17821 aaaaagagag tgtgaaatca gctagctatt actaaaagct agctgattga acatcgttac
    17881 aggaaagagt ttgagcctca ctcttagctt cgattcataa ggagatgtga cataaatttt
    17941 gtcgcatctc ttttttagtc tactcttatt atgtaggaga aggagggagg tggatcatgt
    18001 atcaagagtc aataaagtag ttgataaaat cgttcctctc tctgtttctt ttctctttgt
    18061 catactttta tttttcttat gtgttctatt tgttataata aaagagaaat gggggaattg
    18121 ttgatgacga ttgaagaagc aatagaatgg atccatagtc gattaccatt tggttcacgt
    18181 cctggccttg accgagtcga agctttatta gaagtggtag ggcatccaga gagaaaagta
    18241 aaaacgatcc atatcgctgg aacaaacgga aaaggttcta ctgtagctta tttgagaagc
    18301 ctattagaag aggctgggct gacagtaggt acatttactt caccttatat cgaaacgttc
    18361 aatgaacgga tcgcaatcaa tggcaaaagc attccagaca atgatttgat ccagcttgta
    18421 aaaaaatatc agccactgat caaacaactt gatcaatttg aagcagtagc tggtattact
    18481 gaattcgaga cattaacagc aatggcattt gattattttt tgatgaagaa agtggacgta
    18541 gcgattatcg aagttggctt aggcggctta ttggattcta ccaatgtagc tgtaccaatg
    18601 ctgacgggaa taacaacgat tggacttgat cataccgaaa tacttggaga tacaattgaa
    18661 gaaatcgctg cacaaaaagc tggaatcatc aaacaaggcg ttccagtagt aacaggaaat
    18721 attgccccag aagcttttac tgtcatccaa caaacagcta aagcaaaaaa tgcaccgctt
    18781 tatgtatacg gggaaaatta taaaataaac tatctgcatc ctgatgagat gtggggagaa
    18841 gtatttgaat tttttaatga aataggaaag atccctcaat taaccactcc gcttttaggg
    18901 caacatcaag ctgaaaatgc aggagtagcc atcgaattgt attttgttta ctgtcaattg
    18961 gaaaagctgc ctttccgaga aaaagatgtt ttgaagggat tgaagaaatc tcgatggcca
    19021 ggaagaatgg agcgtttgag taacgagcca ttagttgttt tagatggtgc ccataatacg
    19081 catgcaatga accggcttgt tgagaatttg aaaaaagaat tcaaaggata tcaaatcaac
    19141 attttgtttt ccgccttacg aactaaaaat gttagagaaa tgctagaacg attgcagcaa
    19201 gtaccaaatg tccatattta tttgacgacc tttgaacatc caaaagccat cgaattaagt
    19261 gaagtatcag atttagcaag tgagagagta tcaatcgttt cattgtggca attcggatta
    19321 gcagatatat tggaaaagat gacaaatgaa gacgtattag ttgtgaccgg ttcactttat
    19381 ttcatttcag aagttcgcca tttattaata caattaggag gagatcatga agtataatgc
    19441 agtgattttt gacatggatg gtttgctgtt cgacacagag ttagtgtatt acgaagccac
    19501 acaagtagta gcagacaaga tgggttttcc ttatgataaa gacctgtatt taaaattctt
    19561 aggtgtttca gatgaagaag tatgggcgaa ttatcatatg attttctcgg aatttggcaa
    19621 aacaagtgta caaagattca tagatgattc ataccaggaa acgcttgaac gtttttcgca
    19681 aggagcggta caaatgaagc ccggtgtgtt ggaactcctc tcttttttag aagaacatca
    19741 gattcccaaa gttgtcgctt ccagtaacca acgagcagtc attgaacttt tattgaagaa
    19801 gaacaatctg tttgaacgat ttgagacgat tgtttctgca gaaaatgttc aacgagcaaa
    19861 accagaccca gaaattttct tgttagctaa tcagaagcta ggtacagcga agaaagaaac
    19921 attgatttta gaagattcac aaaatggtat tttagcagct tctgcggctg agatcccggt
    19981 agtcatggta ccagatctgc ttccaccatc ccaagaattg atcaaaaaaa cagctggggt
    20041 tgtttcttct ttacatgaaa tccctgcatt gttaaaataa aaatccatct cttttcgtat
    20101 cttattttag ataagataga aaggagatgt ttttttggga aaacgattga tcaaagaagt
    20161 acctactagc tctttaccaa gggaacgtat ggaaatttat ggcgcggaag ctttatcgga
    20221 tcaggagctt ttggcaatct tactgcgtac cggtcaacac ccttatagtg tgatgtcgat
    20281 tgctggaaat ctgttaaaaa cgtttggagg actggcctct ttacgacagg ctactttgca
    20341 tgagttagaa gagattcgag ggataggacg cgtgaaagca atcgaaatca aagccttgat
    20401 cgaattaggt cgacgaattc agacggatca tgaaagagcg gctccaccgg ttcgtaccag
    20461 ctacgaattg gcccagcaat tgattctgga aatgaaagat cacaaacaag aacatttggt
    20521 ttgtatttat ttggacacga agaatcaagt gatcttaaaa aaaacagtgt tcatcggttc
    20581 gctgaatcag tcagtcgctc atcctagaga aattttccat tatgctgtac gttattgtgc
    20641 agcaaggatc gttttagcgc ataatcatcc ttctggtaat gttattccat cgcagcagga
    20701 tatgaatttt accaaaagga tacaaaagtg tggagaaatg atggggatca ctgtactgga
    20761 ccacttgatc atcggacgca aacgatattt tagtttgaga gaagaaggaa tgatggaaga
    20821 gaagtaagtt gctttcttgc aaaaaaaatg aagcaagtgt acaattatat tgtaattttg
    20881 tttgggaata gaagttgaaa catctgttgc acctctatcg tacacgagca atgttacaat
    20941 ttaaattagt gcttttggca cgaggaggat attattatgg aaaacggaac agtaaaatgg
    21001 ttcaacgctg aaaaaggatt tggatttatc tcacgtgaag atggaagcga cgtattcgtt
    21061 cacttctcag ctatccaagg tgacggattc aaaacattag aagaaggtca agcagtgact
    21121 ttcgacgttg aagaatcaga ccgcggccca caagctgcaa acgttgtaaa agcttaattt
    21181 tatctgtaaa tcaaattgat ggtagacatc aatttttacg agagaacaaa gcgagtaaca
    21241 aaaatacctg ccacaagaga caatttctct tgtggcagg
//
LOCUS       DAYNVV010000048        21247 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.048, whole genome shotgun sequence.
ACCESSION   DAYNVV010000048 DAYNVV010000000
VERSION     DAYNVV010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.048"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(137..514)
                     /locus_tag="ACGXWR_001988"
     CDS             complement(137..514)
                     /locus_tag="ACGXWR_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803538.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            770..1498
                     /gene="purC"
                     /locus_tag="ACGXWR_001989"
     CDS             770..1498
                     /gene="purC"
                     /locus_tag="ACGXWR_001989"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFK0803539.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1498..1752
                     /gene="purS"
                     /locus_tag="ACGXWR_001990"
     CDS             1498..1752
                     /gene="purS"
                     /locus_tag="ACGXWR_001990"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HFK0803540.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1754..2425
                     /gene="purQ"
                     /locus_tag="ACGXWR_001991"
     CDS             1754..2425
                     /gene="purQ"
                     /locus_tag="ACGXWR_001991"
                     /EC_number="3.5.1.2"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HFK0803541.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2426..4648
                     /gene="purL"
                     /locus_tag="ACGXWR_001992"
     CDS             2426..4648
                     /gene="purL"
                     /locus_tag="ACGXWR_001992"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HFK0803542.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4633..6072
                     /gene="purF"
                     /locus_tag="ACGXWR_001993"
     CDS             4633..6072
                     /gene="purF"
                     /locus_tag="ACGXWR_001993"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HFK0803543.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6095..7147
                     /gene="purM"
                     /locus_tag="ACGXWR_001994"
     CDS             6095..7147
                     /gene="purM"
                     /locus_tag="ACGXWR_001994"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HFK0803544.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            7144..7722
                     /gene="purN"
                     /locus_tag="ACGXWR_001995"
     CDS             7144..7722
                     /gene="purN"
                     /locus_tag="ACGXWR_001995"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HFK0803545.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7719..9254
                     /gene="purH"
                     /locus_tag="ACGXWR_001996"
     CDS             7719..9254
                     /gene="purH"
                     /locus_tag="ACGXWR_001996"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HFK0803546.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9270..10544
                     /gene="purD"
                     /locus_tag="ACGXWR_001997"
     CDS             9270..10544
                     /gene="purD"
                     /locus_tag="ACGXWR_001997"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HFK0803547.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10666..11580
                     /locus_tag="ACGXWR_001998"
     CDS             10666..11580
                     /locus_tag="ACGXWR_001998"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HFK0803548.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11713..13278)
                     /locus_tag="ACGXWR_001999"
     CDS             complement(11713..13278)
                     /locus_tag="ACGXWR_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0803549.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13271..14722)
                     /locus_tag="ACGXWR_002000"
     CDS             complement(13271..14722)
                     /locus_tag="ACGXWR_002000"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFK0803550.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14736..15752)
                     /locus_tag="ACGXWR_002001"
     CDS             complement(14736..15752)
                     /locus_tag="ACGXWR_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFK0803551.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTSDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15972..17060
                     /gene="chvE"
                     /locus_tag="ACGXWR_002002"
     CDS             15972..17060
                     /gene="chvE"
                     /locus_tag="ACGXWR_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     substrate-binding protein"
                     /protein_id="HFK0803552.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17114..18640
                     /gene="mmsA"
                     /locus_tag="ACGXWR_002003"
     CDS             17114..18640
                     /gene="mmsA"
                     /locus_tag="ACGXWR_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     ATP-binding protein"
                     /protein_id="HFK0803553.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18642..19847
                     /gene="mmsB"
                     /locus_tag="ACGXWR_002004"
     CDS             18642..19847
                     /gene="mmsB"
                     /locus_tag="ACGXWR_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     permease"
                     /protein_id="HFK0803554.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20104..21081
                     /gene="guaC"
                     /locus_tag="ACGXWR_002005"
     CDS             20104..21081
                     /gene="guaC"
                     /locus_tag="ACGXWR_002005"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HFK0803555.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
BASE COUNT         6813 a         3596 c         4822 g         6016 t
ORIGIN      
        1 ataaccaaaa aagaagcaga tccgttagcg gttctgcttc ttttagttta ttatattttc
       61 ttatcaataa taggaacctg attttaaaag cggctacctc tttaccgtgc ctctttacat
      121 acaaaaaata gaggaattaa gcgtaaatgg cttggctatt ataactaaaa tgctggttat
      181 ggagatgttg cagcaagttt tcgagaaaag cgtattccat ctcttgtcca ttgaataaga
      241 tctggatacg ataatgattt ttgaaacgct tctgttcatg aatctgactg attgaaagtt
      301 cgcctttgtg ttctgtctga taaagaaaag tccttttacg gcattcagca cagcgcttgg
      361 ttgctcggcg gatttttcgg aatgtataaa aactagtatc tttattgcat aaataaacgt
      421 ctttgatcga cagcaaatca ttatatagac aggaacgttc ttcagctgtt aattctgata
      481 aaaaaagctg accttgtttt attgcatctt ccatcggcaa gtgcctcctc gaacccatta
      541 tccaaatttt tagttaattc taatatacca tcattaagta taaatgtaaa cgcttgttga
      601 tggtataaga ttttcgtttc tgataaaaca cgaacattaa aagaatctaa tgccttaaat
      661 gtacatattt ttgttgattt ataaaaagat gattgctaaa atttaaagtg aaaaaacgaa
      721 caaaaaacga tgtatttgct tttaatgtaa ataaaaagga gagacgtaca tggagaagaa
      781 agaacttttg tatgaaggaa aagccaaaaa aatatatctt acttctgatg agaacttgat
      841 ttggatagaa tatttagatc aagcaactgc gttgaatggc gcgaggaaag accagataag
      901 tggaaaagga gaattgaata atcaaatcac aagtgcaatt ttccgttatc tgactcaaag
      961 aggaataaaa aatcatttta ttgaacaatt gtctaaaacc gaacaattag caaaaaaagt
     1021 acaaattatc cctctggaag tggttatccg aaatattgca gcaggaagtt tctcaaaacg
     1081 tctaggtgtt cccgaaggta aagaattcat caaaccaatc attgaattct actataagga
     1141 tgaccagttg gatgatccat ttatcaatga agagcatatc tatttcttac aacttgcaaa
     1201 gccggaagaa atcagtgagc tgaaagccca agcgttggct attaatgaaa ttttgaccga
     1261 attatttgct aaggtcggtt tggttttagt agatttcaag ctagaatttg gccggtcgaa
     1321 tggacaaatt ttgcttgcgg atgaagtaac accggatact tgccgattat gggatgaacg
     1381 tacgaatgaa catatggaca aagacgttta ccgcagagat ctaggtgatt tgatcccagt
     1441 ctatcaagaa gtatataacc gtctatcgga actaactgaa gaaaaggagc gagtatgatg
     1501 tatttcgtaa aagtatatgt aacctataaa gattcagtgt tagatcctca aggggaggca
     1561 gtaaaaaaag cagtccatcg tatgggatat gaaacaatcg aagatatccg aataggaaaa
     1621 tactttgaga tacaacttgc tgatgcagaa gaaccaatcg atacagtgat tgaaacgatt
     1681 tgtgacaagc tgcttgcaaa tgtaaatatg gaaacatacc gatatgaaat caaaaaaatg
     1741 gaggaagtat aacatgaaat ttgcggtcat cgtttttcca ggttcaaatt gtgacgcaga
     1801 tatgttatgg gcagttcgcg agatcatggg cgctgatgcc gaatttgtac ggcatgatga
     1861 gtcctcttta gaaggatttg atggggtttt actgccggga ggattctcct atggtgacta
     1921 tttgagatgc ggtgcgattg ctcggttttc tacaatcatg gaagaagtga ttcgttttgc
     1981 tgaagaaggg aaaccagtat tcggtacatg caatggattc cagatattga cagaagcagg
     2041 acttttgcca ggtgtactga gacgaaatga gtctttgcat tttatttgca aaactgtacc
     2101 attgaaagtc aaccccaaga cggcctttac ttcagagtat gaagccgacg aaataatcta
     2161 tcttccagtt gctcatgggg aaggaaatta tttctgtgac gaagaaacac ttcaagaact
     2221 aaaaaaaaat aatcagattg cctttactta taatgacaac atcaacggca gcgtggaaaa
     2281 cattgcaggg attacgaaca aagcagggaa tgtgttagga atgatgcctc atccagaacg
     2341 tgcagtagaa gacttgctag gatcagaaga tgggaaacgg ttctttgctt ccattttaaa
     2401 aaacttcgga aaggtgaccg tatagatgaa aacattgaaa gaaccgacag ctgaagagat
     2461 caagaaaaaa agaatctatg ccgaatgggg attgactgat gaagaatatc gaatgatcga
     2521 agaagatatc ttaggaagaa tgcctaatta tacggaaact ggactgtttt ctgttatgtg
     2581 gagcgaacat tgttcctata aaaattctaa accggttcta cgcaaatttc ctactagtgg
     2641 acctcatgtg ttgcaaggcc ctggagaagg cgcaggcatc gtcgacatcg gtgatggact
     2701 agcagttgtc ttcaaagcag aaagtcacaa tcatccttca gccgtggagc cttatgaagg
     2761 agctgcgaca ggagttggcg gaatcatcag agatattttc agcatggggg ctcgtccaat
     2821 tgcgttgcta gattcattga ggttcggcga attagataat ccaagaacga aatatttact
     2881 agaagaagta gttgcaggta tcggcggata cggcaattgt atcggcatac cgactgtagg
     2941 cggcgaaatt gcatttgatc cttgttatga aggaaaccca ttagtcaatg caatgtgcgt
     3001 aggtttgatt gaacacaaac atatccagaa agggcaagcc gctggcgtcg gtaattcgat
     3061 catgtatgta ggtgcaaaaa caggtcgcga cggtatccac ggagcaactt ttgcctcaga
     3121 agaatttaat caagaagaag aacagcaacg ttctgctgta caagtaggcg atccttttat
     3181 ggaaaagctg ctgcttgaag cgtgtttgga attaatcttg catcattcgg attctctaat
     3241 aggtatacag gatatgggag cagcaggact tgtttcatct agtgcggaaa tggcttcaaa
     3301 agctggctca ggacttatat tgacattaga tgaagtccca caaagagaaa ctgggatgac
     3361 accttatgaa atgatgttat cggaatcaca agaacggatg ttgatttgtg ttaaatcagg
     3421 agaggaagaa aaaatccaag aactatttca gaagtatgat ctagatgcag tcactatcgg
     3481 taaagtaaca gacgacgggc aatatcggct atatcatcaa ggagaagaag tagcaaatct
     3541 gccagtcgat gcattagctg aagatgcacc agtttatcat aaagaaatga aagaaccagc
     3601 tcgaatcgta gaatttcagc agttagctcc ttatcagcca gttatcgaag aacctggaca
     3661 agtattgctt gatctgctgc agcaaccgac gattgcttca aaacgttcaa tctacgaaac
     3721 ttatgattca caagtacaaa ccaatacagt tgtccgtcca ggaagcgatg ctgctgtgat
     3781 gagggttaga gggacgaata aagcgttagc tatgaccaca gactgcaacg cgcgctatct
     3841 gtatttggat ccaaaaatcg gaggacaaat agcagtggca gaagctgcta gaaatattat
     3901 tgctagcggt ggtaagccct tggcgatcac cgactgcctg aactatggtt ctcctgataa
     3961 accagaagtt ttttgggaat tatcgacttc agctgacgga attgctgctg cgtgtgaaac
     4021 gttaggaact cctgttattt caggaaatgt ctctttatat aatgaaacgg atggtcaagc
     4081 aatctatcca acaccaatga ttggtatggt cggattgatt gaggatcata aacatatcac
     4141 tactcaggaa ttcaaaaaat caggggatct aatctatata ttaggtaaga cgtttgcaga
     4201 ttttgatggc agtgaattac aaaagatgca gcttggaaga atcgaaggtg tgatccgaaa
     4261 ctttgatcta tccattgaaa agagaaacca agagttagta ttgacagcca tccaaaacgg
     4321 attgattgaa agtgctcatg actgttcaga aggtggcttg gcaattgcac tggcagaatc
     4381 agctttcaaa catcagctag ggatatctgt acagtttgaa ttgtcctctg ctcaattatt
     4441 tgcagaaact caatcaagat ttgtgttgac agtcgcaccg gaaaataaga cacgattcga
     4501 agaaatgatg ggagatgctg ctgttttagc aggtaaggtg acggatgaag cgataatcga
     4561 aatttcagca actgacggtc agatcaaaat agaaactgca gtagcaagaa agtgctggga
     4621 ggatgcaatc gtatgtctta tgaagtgaag agtttaaatg aagaatgcgg gatcttcggt
     4681 gtttggggtc atccagacgc cgctagtgtg gcatacttcg ggctccatag tcttcagcat
     4741 cgaggacaag aaggtgcagg tatcgtgtcc aatgatcgag gaaagcttaa ggggcatcga
     4801 gatttggggc tgctttctga ggtattcaaa gatcaaagaa aattgcagca gttaacagga
     4861 gaagctgcaa tcggacatgt acgttatgca acagcaggca atggaagtgt ggacaatatt
     4921 cagccttttc tattcaaatt tcatgatcag tcgatcggct tagcgcataa tggtaacttg
     4981 atcaatgctc gttcccttag aaaagagtta gaggaaaatg gggcgatctt ccattctaac
     5041 tccgatacgg agatattgat gcatttgatc cgacgaagtg aagaaacaga ttttttaaat
     5101 aaattaaaaa gtgctttgaa tgaagtcaaa ggtggctttg cctatttatt aatgacagaa
     5161 acggcaatga ttgccgcttt ggacccaaat ggttttcgtc cattagcaat cggacaaatg
     5221 aaaaacggag catacgtgat tgcctcggaa acttgtgcat tagaagttat tggggcacgt
     5281 tttataagag atgtccagcc tggtgagata gtgatcatca atgacgaagg aatccagatt
     5341 gattgcttta cgaaggacac gcagctttct atttgttcga tggaatatat ctattttgcc
     5401 agaccagatt caaacatcgc agggatcaat gtgcatactg cacggaaaaa tatgggacgg
     5461 aatttagcga aagaatcgcc agtaaaagca gatatggtcg ttggcgtacc taattcttct
     5521 ttgtcagccg caagcggtta tgcggaagct agtggaatcc cttatgaaat cggattagta
     5581 aaaaatcaat acattgcccg aacatttatc cagccaacgc ctgagctaag agagcaaggt
     5641 gttcgaatga aattatctgc tgtacgagga gtagtggaag gtaaaaaggt gattatggtc
     5701 gatgattcaa ttgttcgggg tacgacaagc agacggatcg tccatctttt gaaagaagca
     5761 ggggcaaaag aagtccatgt gaggattgct tctcctcctt tgaaatatcc atgtttttac
     5821 gggattgata ttcaaacgcg taaagaactc attgcggcaa atcacacgat tgatgaaatc
     5881 aaagaatgta tcggtgcaga ttctttaggt tttttaagtg aagagggtct gatcgaatcg
     5941 atcggtctgg aaaaagatgc tccgtattca ggattgtgta tggcttattt caacggagat
     6001 tatccgacgc cgttatatga ctatgaagaa aaatatcagg aatcactaaa agaaaaagta
     6061 tcgttctttt aaaagcagac caagaaggga gtatatgaat tcaatggcaa atgcatacgc
     6121 aaaagctggc gtagatgtcg aagctggata tgaagtagta gaacggatca agaagcatgt
     6181 caaaaaaacg gaacgtttag gtatgatggg cgctatagga ggattcggcg gttgttttga
     6241 tttatcggtc tttcaattaa aagagccagt ccttgtctcg gggaccgatg gcgtggggac
     6301 gaaattagca gtggcaatcg aagcagacaa acacgataca atcgggatcg actgcgtagc
     6361 gatgtgtgtc aatgatatct tagcacaagg cgcagagccg ttatatttct tagactactt
     6421 agcaacgggg aaaaatgatc cgttacgttt ggaaaatgta gtaaaaggtg tagcagatgg
     6481 atgtgttcaa ggaaatatgg cgctgattgg cggagaaaca gctgaaatgc ctggtatgta
     6541 ctcaggtaat gattatgatc tagccggatt tgctgtaggg atagctgaaa aatctcaatt
     6601 attgacagga gaaacgatca acccaggaga tgtgttgctt ggaatagcat ctagcgggat
     6661 tcattcaaat gggtactctc ttgttcgcaa aattttcttt gagcagcagc agttttcttt
     6721 atcatcaaaa ctgccagaat tgaaaaaaac acttggcgaa gaattgcttg agccaacgaa
     6781 aatctatgtt tcttccttgc ttccgctgat caaagaaaag aaaataaaag gagctgcaca
     6841 tatcactggt ggagggtttg tagaaaatat cccgcgaatg ttaccagaat ctatggctgc
     6901 acaaatcaaa cttggctcat ggccgattct tccaatattc ggctgtttac aaaaatatgg
     6961 tgaaattcct gagatggaga tgtatgaaat cttcaatatg ggcatcggta tggtcctggc
     7021 agtcgaagaa tcgaaagtaa aagaaatagt acacgaaatt gagcaagctg gcgaaaaagt
     7081 ttatgaaatc gggaaagtga tcgccaaaga aaaacatcgt gtggtgttta taggagaaga
     7141 acgatgagaa tcgctgtttt tgcttctgga aacggaagca actttcaagc gctagccgat
     7201 tatctatcga aaaaaggatt ggaatcttcg attgactggt tgttttgtga tcagcctgaa
     7261 gcatatgttt tgaaacgtgc aactgcgttg agtgtaccgg cagattgttt ttcacctaaa
     7321 gaatttgatt caaaaaaaga gtatgaagaa gcaattttgc ataaattgaa agaaaaaaag
     7381 atcgatttga tcgtattagc tggatatatg cgaatcattg gaccggtatt gctgaaaaat
     7441 tatgataaaa gaatcatcaa tatccatccg tctcttttac ctgccttccc tggtttgcat
     7501 ggcatacgtg atgcctttga agctggagta aaagaaacgg gtgtcacaat tcattatatc
     7561 gaccaaggtg tagatactgg accaatcatc cggcaggaaa aagtgagaat tgaacaggag
     7621 gacacgttcg attctttaga agaaaaaatc catagagtag agcatcgaat ctatccagaa
     7681 gtgattagtg aaattattga aaatggaggc tatctgaaat gacaagagca ttgatcagtg
     7741 tatcagataa aactgggatt gtagcattcg cccaaggttt gattgaacaa ggagtagaaa
     7801 tcatttcaac aggaggaaca aagcatgcgt tggataaagc tgggatcaaa acgctttcga
     7861 tcgaagaagt gacagggttt cctgaaatga tggatggccg tgtcaaaaca cttcatccta
     7921 aaatccatgg tggtctttta ggaagacgcg atctccctag ccatatggag gcaatggaaa
     7981 cggaaaatat ccaaccaatc gactttgttt gtgtcaattt atatcctttc aaagaaacga
     8041 ttatgaaacc agatgtcgaa atagcagaag ctattgaaaa cattgatatc ggtggtccta
     8101 gtatgctccg tagtgcagca aaaaaccatg aatttgtcac ctctgttgtt gatccatctg
     8161 actatgaaga agtactttca gaattacgtc agtatgggca tacttcactt tctttcagac
     8221 aaaaactagc ggcaaaagtc tttcgtcata ctgcggcata tgatgcactg atcgctcaat
     8281 acttaacgga ttgggtggaa gaaaaagaac cggaaaaatt gacacttacg tatgaacgaa
     8341 aacaaacgct tcgttacggt gaaaatagcc atcaagccgc tgccttttat cagtccgctc
     8401 ttctggaaaa atattcgatc gcagcagcaa aacaactcca tgggaaagaa ctttcttata
     8461 ataatatccg agatgcagat gctgcgctac ggatcatgaa ggaatatgac gagccaacgg
     8521 tagtcgcctt gaaacacatg aatccttgtg gtattgggac agcatctacg attttagaag
     8581 cgtgggaagc agcgtatgaa gcagatcctg tttcaatctt tggtgggatc atcgttttga
     8641 atcgagaagt agatctgcca acagcagaac agatgcataa gctgtttcta gaaatcatca
     8701 ttgccccttc ttatacacaa gaagctttgg aattactgca aaaaaagaaa aacatccgat
     8761 tactgacagt agactttgcg caggaagaaa atcaaaatcg agaagaaacg gtctcagtct
     8821 taggtggact tcttgtacaa gatcaagatc tggcaataga aaatgaagaa gagtggaaag
     8881 tcgtgacaaa acgtaagccg actccagcag aagcaaaagc attagcgttt gcttggagag
     8941 ctgtcaaaca tgtgaaatct aatgcgatcg tactggcaaa cgaacgtcag acagtaggaa
     9001 tcggagccgg gcagatgaat cgagtcggtt cagtaaaaat tgcgattgaa caagcgcaag
     9061 agaaaatgga aggtgcagtt ttagctagcg atgcttattt tccaatggat gattcggttg
     9121 aatatgcagc caaacatggt ataaaagcaa tcattcagcc aggaggaagc atcaaagacc
     9181 aagattctat tgatatggcg aataaatacg atctagcaat ggtctttact gatgttcggc
     9241 attttagaca ttagagagga gtcggataaa tgaacatttt ggtgatcggt gcaggtggtc
     9301 gtgaacatgc aataagtaaa aaacttttag ccagtccgaa ggtggatacg gtgtattgtg
     9361 cgccaggaaa tccggggatg acaaaagatg gtatcaattg tgtcgctatc agtgagcgag
     9421 atcattcagc gttaatccat tttgttaaga aagaggctat tgattggagt atcgttggtc
     9481 ctgaagttcc tttgttaaat gggatcgtcg atgattttat ggcggaagga ttgaaaatct
     9541 tcggtccgac aaaagcagca gctctgatcg aaggttcgaa aagttttgct aaacaattaa
     9601 tggatactta tcaaatcccg acagctaaat ccagaagttt tgaatgttac gaaaaagcag
     9661 cagcgtatat caaagaaaat ggtgcgccaa tcgtagtgaa agcggacggc ttagcagctg
     9721 ggaaaggtgt agtcgtggct accacagtga aggaagcgct ggatgcggca gaacaaatgt
     9781 tgaaccagca tcgatttggg gatagtagca aaaaaatcgt cgtagaagag tttttggcag
     9841 gagaagaatt ctcccttttg gcgtttgtcc gtaataccaa ggtgtatccg atggtcattt
     9901 cgcaagatca taagcgggca tttgataacg ataaagggcc aaatacaggc ggaatgggtg
     9961 cttattcacc agtaccgcaa atttcaaaaa agatgattga aaaagctgtg gaagaagttt
    10021 taaaaccagc ggctttggga atgaaagaac taggacgctc tttcacgggt gttttatatg
    10081 cgggtttgat tgctacgaag gaaggaccaa aagtgatcga attcaatgcg cgtttcggtg
    10141 atcctgaaac gcaagtcgtt ctttctcggt tgaagagtga ctttgcgcaa gtaatcgatg
    10201 atttattaga gaatcgtaca gtagagttaa agtggcagca agaaggatac aatgtaggcg
    10261 ttgtggttgc agctgccggt taccccgaag aatatgagac aggaatggtt ctaccagatt
    10321 ttctggaaga agagctttct gtttactatg ctggagtttc ctcaaataac ggcaaactag
    10381 ttggagcagg aggacgtctt tatttagtag aagcatacgg tgagacgatc aaagaagcac
    10441 agaaaaaaat ttacaccgcg ttaatggata aaacgacaga tggaacattt tatcgtacag
    10501 atattggaga aaaagctgcc aatagcgaac tgatcgtgaa gtaaatcagc tgcttccatt
    10561 tataaaaaat acaacaaaca taatcggaag cgccgatttt agtgaagcct tttcataaag
    10621 agtgtggtac acttttgttg tgtatataaa taaggaggag ttcagatgaa aaaaattcaa
    10681 ttaggtactt ctgatcagaa agcagctgca gtgatcttag gctgtatgcg tatcaacaat
    10741 gcggaagatc cagtaaaagt gattgagaca gcttatgaaa acggcattga tttttttgac
    10801 catgcagata tttatggaaa cggtgaatgt gaagaaatct ttgcagatgc tctagcaaaa
    10861 acatcaatca aacgagaaga tctttttatt caaacaaaat gtggaatcgt tccaggtgtg
    10921 atgtttgatt tttctaaaaa acatatcatt gaatctgtag aaaaaagttt gacccgtctg
    10981 aaaatggatt atgtggatgc tttacttctt catcgtccag atacattggt agaaccagag
    11041 gaagtagctg aagcgtttga tgaattggaa cggtcaggaa aagttcgtta ttttggcgtc
    11101 agcaatcaaa aaccaatgca aatcgaattg ctgaaaaaat atgttcgtca accattagta
    11161 gctaatcagc tgcaatttgg cttgaaacat actggaatga tcgatcaagg gattcatgtc
    11221 aatatgacag atgaagcaag tatcgatcat gacggtagtg tacttgatta ttcccgattg
    11281 catgatatga cgatccaagc atggtcacca taccagtatg gattttttga aggtgtattt
    11341 atcgggaacg aaaaattccc tgaattaaac caaacattag aagaactagc agctaaatat
    11401 caaacgacac caactggctt ggcttctgct tggattttac gccatccagc caatatgcaa
    11461 gtgatcgccg gtacgatgaa cgtagggcga atcaaggaaa tcgctcaagc ttcagaaatt
    11521 aatatgtctc gggaagattg gtacgaattg taccgtgctg ctggaaacat tttaccttaa
    11581 agattgtcat aagcaggtca aaagggctat aaattaaaaa gacagaataa cttgaaagct
    11641 gttttcagct tcgagatatt ctgtcttttt ttattgcaaa tggaaagagt atcattgtac
    11701 ggatttcgtt tattagttat ttttgttttt aaggaaaagc tgtgtccgat attcttttgg
    11761 agaaatccct tgttttttct taaataaata actgaaatag ttagggtcat tataaccaat
    11821 ttcaaaagca atatctgaaa tacgatagtc tgattgctgc aataattttt ttgctaattc
    11881 gattctttgt tctgtcagat aatcgatgaa tgtttggtta aacgattgag aaaaaatcgt
    11941 actgaaatga gagggactta atgcaacttg ttgagcgacc caagttaagg acatatctgg
    12001 atcggtaaaa ttttctttga taaaatccaa tgcatggttc aaaattggct gatatttgtt
    12061 ccttgaaggc tgtgagggca gagcagttaa gaaagaaatg aacatataaa ctgtcgaacg
    12121 gtaaagcgag tcgtcggcgc tgattgctaa gcgttgactg gtggatgtgc aatgaaccat
    12181 ttcttgcggg attttctttt ctttcaggca gacatgctgg agtagcttag tcaagacaaa
    12241 taaacgatat aatcgtgttc gagttggtgt gccttgtggt ttcgtcaagt gttcgatgta
    12301 cttagatact tcgtttttcg ataatgaaga caaatcaagt gagaggtcaa agtaaaagac
    12361 agaatcaact ggaagtttcg cttcttgaat caaatcctca tagctgataa tttgttcttt
    12421 aagggaactg gcggtttcaa gtatcatctg cgtgatctca aaagatgcag gtaattcgct
    12481 gattctttct gcgacaggac caatggcgac agaaaaatta tttttttgtc ccttttctaa
    12541 ttcatggacc aacgtttggg ctacctgata actggtctcg atcacatttt cttcaagaga
    12601 atcaactatt aaaaatttga tgaatcgaga ggaaacagca gagaagatca cttgttgatt
    12661 ctccctaaat aaaaacttca aataatcact gagatgagcg taatcttcaa agtctgtact
    12721 gacttggttt gctgctaata atacggtcat ttttttccct gctaaagagc gattgaaaga
    12781 ttcagcaagt ttcaatgttt cactgatcgt aagtgagcct ttgaacaaac cgttcaagaa
    12841 atgatttttt ttcaattcga aaacaagatc agaagaagtg tgcgtttctt tttgctgcaa
    12901 atctaaagca gttactgctt tttctattgc ttgtttcaat tcgctacttt taatcggttt
    12961 aagcagataa tcatctgcct gtacctggat tgctcctttc atataatcga aatcgtcgaa
    13021 tccactaata aatatgagac gagtccaagg aagtagtttc cttgcttctt ttgaaaaagt
    13081 caacccgtcc atgaaaggca tttggatatc agtcagaatg atgtcgggct gtaagtcgat
    13141 aattgaagac agtgccatct caccatctcc agcttcgccg acataagtga ttggataata
    13201 agaaccaagg acagttattt gttcccgcaa gttattgcga atgaggtatt cgtcttcgat
    13261 gataaaaact ttatacatgt ttgtttcctc caattgtttt gggagataga gggatcatca
    13321 gtgtgacagt tgttccttct cggtatttgc tgtcaatcgt gataggtttt tgatcatttc
    13381 cgtaataaag aaggagacgc ttgtttacgt tgtaaagtcc gtagccgata ctgaaatctg
    13441 aatcgatccc tttggctaac tctttacgta tttctgccag tttttctgca gggatgccaa
    13501 tcccgttgtc tataactttg aattggatca tctcatcaat tttgcatgtg gtaatacgaa
    13561 taaatccttt gtgacggacg tacttcgttc catggtatac agcattttca atcaatggct
    13621 gcaagatcat ttttaaaata gaaacaggaa aaagtgtttc tggtatatcg atcttatagt
    13681 caagcatatg gccgtatctt atttttaaga tgactagata atcattgata tggctaattt
    13741 ctttttcaag aggaatccag tcttgtcctt tgcttaaaga cgtacgaaaa aagccggaaa
    13801 gtgcatgggt catagtcaga gcttcttcaa agcagtcttg ttcgatcaaa gaaataatgg
    13861 catccaaact gttataaata aaatggggag taatctgagc ttgcaataca cgaacttcac
    13921 tttgtgctaa atggtattgt ttcaaagcgt tctcccgtaa agactggttt agatcttccg
    13981 ccattttatt catgctagcg gtaagtgttt gtaattccag tgtttccggc agggttaaac
    14041 gaaagccaag gttccctgaa gaaagttgtt ctgacatctc gatcagctga ttgatcggtt
    14101 cttggacctt tctctctaaa aagcgacgat tctttttcgc atagaaaaaa atggtactaa
    14161 gaactccaag ttccactatt gttaatagaa tgagcgagcg gacaagtgtc gtattttttt
    14221 tgcttgctaa gtcgatctcc acacgaacaa aatcttgtaa gatatctgac agcagttgag
    14281 tgacagaatc tacctgattg atgatctctt cattggtatc cataaaatct tttgccaaga
    14341 tattattgat cagctcgttt tgataatctt ccagtgtatc gatcgtacgt agcgatacat
    14401 ctaacgtact aatttcttta agtgtatttg tattattttt gatctctcga atatcattcc
    14461 taagttcttc taggatattt tcctcattga actcatctac ggttacttgg ccagaaatca
    14521 agtcccacat actttccaaa actttttgat caaccttcaa agcaattgca tctgcttttt
    14581 ggatatttgc gatcgtctgt tgataaatca aaagctgttg cgaatataac agtatgctca
    14641 gtagcaaagg gataacagca aatagaagca tggctttgtt tgcttgggca aaaatctgtt
    14701 ttatgcttaa attttttgtc atgatacttc tccagtcaat aatttctggt tgggatgtta
    14761 gctatattct gctgggaaaa gacagtctcg gaaataaaaa tatctttagg taatgttttt
    14821 cctgtttgaa tatttccaaa ataacgagta acggtattgg ctacatacca gccgacatca
    14881 ggtttacact cgactacaca attgacgatt cctgagcgta gcttctcgat catatcttct
    14941 tgtccatcaa tagttacaat gatcaaatct tctccaggtt tgattgatgt ttcttttatc
    15001 gcagctaaag caccgtgagt catttcatca ctatggctgt ataatacatc gatttcggat
    15061 aaatcatttg tttctaaata tcgtttcatc tggtcttttc ctttcatccg aataaaatca
    15121 ccgacaattc ggtgaacaat agtcatcgga ggtttatggt cgatggttcc atcttttttt
    15181 agggttggtt tacgattgat tgattccaaa aatccttcgg agcgtagctt ggtcggtgtg
    15241 gagttctctg aaccagcaag ttctaggatt ctgatttcct gtttctttga atttgtgaag
    15301 tgattgctga caaataaacc cgcccgattt ccttctgctt tgaaactggg gccaatgtgg
    15361 gtgacgaaaa gctcgggatc actcgtttga atatgtctgt cgacaagtat gacagggatc
    15421 cctgctcgct ttgcttcttt taatacagag tcccacccgg attcttgcaa aggagtaaaa
    15481 atgatcatat ccactttata ggcaatgaac gtccgtatat cttggatttg ccgttcctga
    15541 ttcatgtagc catttcggta gagaacttgg taatcttctt tttcaagcgc agtgataatt
    15601 gattcagtat gctttttccg ccagctactc tccgttcctg attgcgaaaa accaacgact
    15661 agtgggtcag gtgcttcctt tgtattaggt gtacacccca tcatttggta agcgattaca
    15721 acaagggcta aaaaaaataa aacacgtttc actttaaatc actccatctg gatttgttag
    15781 tactatctta tcagataaaa gggaaaatca aagtcaaaag gaatcaatcg aaaaaaatcc
    15841 aagaaactta aaaaaatcca agacaaaaaa agtacaccta aaaaatttaa agtaaatccc
    15901 ataaaaaaat caatgttaac gctttcttta ttagctatac tcggtgtatc aattgaaatg
    15961 ggggataaaa aatgaaaaac aaatttagaa agattgttgg gactatcgct attttgaccg
    16021 caagcattct attaagtgcg tgtggcaatt caggatctgc agatgatagt acggggtatg
    16081 taggaatcgc tatgccgacc aaatcagcag aaagatggat cgctgatggg aacaacatgg
    16141 tctcggaatt agaaaaactg ggttataaaa cagatcttca atatggagaa gataaagtag
    16201 aaaatcaagt agcacaaata gaaaatatga ttacaaaagg ggtagataca cttgtgattg
    16261 cttctatcga tggttcggct ttaactgatg tgttagctaa agcaaaagaa gcagatatca
    16321 aggtgatcgc ctatgatcgt ttactgatga attcagaaaa tgtcgattat tacgcgactt
    16381 ttgataattt tggagtaggt gtatcgcaag cagcttatat tgaagagcac ttaggattga
    16441 aagaaggaaa aggaccattc acgattgaat tatttggtgg ctcgcctgac gacaacaacg
    16501 cactaatcaa ttacaacgga gtgatgtctg ttttacaacc atatatggac aacggtcagt
    16561 tggtcgtgcc atctggacag acgagtttca gtcaaatcgc tacgcttcgc tgggatggtt
    16621 ctacggcgca agcaaggatg gataatctgt taagcgcaaa ttatactgac caaacattgg
    16681 atgctgtttt gtcgccatat gatccaataa gtttaggaat catttcgtca ttaaaaggcg
    16741 tggggtatgg gagtgaaagt aaacctttac ctgtgattac tggacaagat gcgacagttg
    16801 ctggcgttaa atcgatcatt gccggggaac aaacacaaac gatctttaaa gacacacgta
    16861 tcttagcaaa aaatacgatt gaaatgatca aagcaatcag tgatggagaa gaggttccgg
    16921 tcaatgatac tgaaacttat gataatgggg tgaaaactgt ccctacgtat ttagcaaata
    16981 cagtatctgt cgataaagat aattatcaag cagagctgat cgacaccgat tattataaag
    17041 aatccgatct gaaaaattaa gaggaaccaa acaaggaact aaagagatct aagtcagaga
    17101 gaggataaga attatggcgg attgtatttt aaaaatggca gatatcacca aaaaattttc
    17161 tggaatccga gcgttagatt gcgtgaatct gatgattgaa cgtggggaaa tccatgcatt
    17221 gtgcggagaa aacggagcgg gaaaatcaac attgatgaat gtcttgagcg gcttgtatcc
    17281 atatggctcc tatgacgggg aaatctttta tgatggaaag ctgtgtcaat ttaaagattt
    17341 gaaagatagt gaagaaaaag gcatcgtcat cattcatcaa gaattagcac taagtcctta
    17401 tctttcaata aaagagaata tttttctcgg aaatgaacaa gcagaaagag gcgtgattga
    17461 ttgggaactg acagaaaaga aaacatatga actgctgaat aaagtcggtt tgtctatcga
    17521 cccgaatctt ctagtatccc agattggcgt agggcaacag caactagttg aaatagctaa
    17581 agcattatca aaatccgtcc gtctgttgat tttggatgag cctaccgctg cattgaatga
    17641 agaagaaagc gcgaatttgc tgagattgat ccgagagttg aaagagcaag gtgtaacctc
    17701 catcattatt tcacataagc tgaatgaaat cgtggatatc gcagatcgaa tcaccatttt
    17761 acgggatgga cagacgattg agacactaga aaatgaaatg atcagcgaag agcatattat
    17821 tcgcggaatg gtgggcagag atttagttga tcgttatcct gaaagaaaac cggatattgg
    17881 agaagtttat tttaaagtag aagactggac ggtctatcac cctcttgatc acgagcgaat
    17941 cataaacgac cacatcaact tgcatttgaa aaaaggagag attgtaggaa tagctggact
    18001 gatgggagcg ggcagaactg aattcgctat gagtctattt ggacattctt atggaagcaa
    18061 gatatccgga cgtatattaa aggaaggggc agagatatca gttaagaccg ttccttcagc
    18121 cattgcaaac ggactcgctt atgtctcgga ggaccgaaaa tctttaggac tgaatctgct
    18181 gatggatatt cgggaaaacg tgacgctgag cagtttggat aaaataagtc aaaaaggagt
    18241 attagataaa gaaaaagaag taactgaggc agaaaatttc cggaaaaaga tgcgtataaa
    18301 aacaaactcc atccatcaaa ttgtcagtag tcttagtggt gggaatcaac aaaaagtcgt
    18361 tttatccaag tggctgatga cacaacccga tattcttttt ttggatgagc caacccgtgg
    18421 gatagatgtt ggggcaaaat atgagatcta cacgattatc gaagaaatgg cagcaaatgg
    18481 caaagctgtc tgtcttatct cttctgaact tcctgaaata ttagggatgt gtgatcgaat
    18541 ctatacgatg aacgaaggac gtattacagg agaagtctcg cgagaagatg cagatcagga
    18601 agtcttgatg aaattaatga cgaaagaaga ggtgggttaa gttggaacag gcaaaaaatc
    18661 ttacggataa aaaagagaaa aaactaaatt tgaaaagtag agcagctgat ctttttggtc
    18721 gctacagcat ggtgatcatt ttagcgggac tacttattgc gtttcaattg atgacggatg
    18781 gtattttctg gcgtccattg aatataacta accttgttct gcaaaatagc catatattag
    18841 tactagctgc agggatgtta ttagttgtgc tcttaggtca tgtggatttg tcggtagggt
    18901 cagtgatggc gtttgttggt gcaattgcgg gcatgatgat ggtcaatcgc caaatgaacc
    18961 cgtggatgac agttatcgca tgtcttgcag taggcgggct gatcggcgca tggcaaggtt
    19021 tttgggtagc ttatgcaggg ataccggcgt ttatcgtgac tttagcagga ttgctgatgt
    19081 ttcgtggact gacacaagtt gttctaggag gccaatctct agcacctttt ccagctgttt
    19141 tccaaaaaat gtctacgggt tatttaccag acttaagcga aggaagcagc cttcacttct
    19201 tgacattgat tttaggaatg atcatcacga tcgtgttagt tgttggtcaa tggcgaacaa
    19261 gaaatcgtcg gaaaaatcat ttatttgaag tggaatctcc aacagctttc ttggtaaagg
    19321 cggtatttac agcagtcgtt gtactaggaa taacttatat ctttgcctct tatcaagggt
    19381 atccgattat tttgatcatt cttggtttga tcgttgcagc atatgggttt ttgacaaata
    19441 aaacagtagc aggtcgacag atttatgcga cgggcggaaa tcgaaaagcg gctgaactat
    19501 cagggatcaa aacaaagcga atcacgttct gggtattcgt caacatggga gtcatggcag
    19561 ctttagctgg attagtttta gctgctcgat tgaatgcggc aacacctcaa gcaggtacat
    19621 cgatggaact ggatgcaatg gcggcagtat attttggtgg tgcttcgact tccggcggca
    19681 ttggaacaat catgggtgcg attgtcggtg gcttggtcat gggtgtattg aacaatggca
    19741 tgtcgatttt aggcgtcggg gtagactggc agcaggcaat caaaggattg atcttgcttt
    19801 tagccgttgt gctagacttg tataataaga aaaaacgaac aacgtaggag aacgccggtt
    19861 attcagaaaa aagactgtga caagacattt gtcacagtct ttttttcgct aaaagcgaac
    19921 attcattgtt tcgtttgtat agactaaaaa taatatatgt ttttttacca ttcgtataaa
    19981 ttctcttttt gctcttgatt tttttgctta attgagttaa attacatagg gcgctaaaaa
    20041 aagccttgat taaattaata atgttcgtgt tttgctggat gtgaacatca ggaggataat
    20101 gtaatgaaag tatttgatta cgaagatatt caattaattc ctaataaatg tatcgtaaat
    20161 agccgttctg aatgtgatac aacggtcaca ttaggtaaac atacattcaa aatgccagta
    20221 gtgcctgcca acatgcagac gattattgat gaaacaatcg cagaattctt agcggaaaat
    20281 ggttatttct atatcatgca tcggtttgat gaagcagctc gaattccgtt tatcaaaaaa
    20341 atgaaaaagc gtggattgat tacctcgatc agtgttggcg tcaagaaaga ggaatattcc
    20401 tttatagaga agttggcaga agaatcgcta aatcctgatt atatcactat cgacatcgcg
    20461 catggacatg ctaactcagt tattgatatg attcagcata ttaaaaaata tttgcctgaa
    20521 acttttgtga ttgccggtaa tgttggtaca ccggaagccg tccgtgaatt ggaaaatgcg
    20581 ggcgcagatg caacaaaagt cgggattggt ccaggaaaag tatgtattac aaaaatcaag
    20641 acaggctttg ggactggagg ctggcaactg gcagctctta gatggtgtgc gaaagcagct
    20701 cgcaagccga tcatcgctga cggtgggatc agaacacatg gcgatattgc aaaatctgtc
    20761 cgttttggtg cgacaatggt catgattggt tcattgtttg ccggtcacga ggaatctcct
    20821 ggcgaaacaa aagtcgaaaa tggaatcgtg tataaagaat actttggttc tgcttcagaa
    20881 ttccaaaaag gcgaaaaacg aaatgttgaa ggaaagaaaa tctggatcca acacaaagga
    20941 tctttgaaag atacactagt ggaaatgcaa caagaccttc aatcatctat ttcttatgct
    21001 ggaggaagag atctggaagc cattcgaaaa gttgactatg tcatcgtgaa aaattcgatt
    21061 tttaatggag acacaatcta aaaaataaat aaaatattag gatgttgtga aaaagttgtc
    21121 ctgcattaag taataagaac agccaaacaa aaatagttct ttatatgttt tgtttggctg
    21181 gaattattat cgcagataca agcttttgaa catcattatt cagaataagg gactgtgata
    21241 agatttt
//
LOCUS       DAYNVV010000049        20307 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.050, whole genome shotgun sequence.
ACCESSION   DAYNVV010000049 DAYNVV010000000
VERSION     DAYNVV010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20307
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.050"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            194..493
                     /locus_tag="ACGXWR_002006"
     CDS             194..493
                     /locus_tag="ACGXWR_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803556.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(590..1024)
                     /locus_tag="ACGXWR_002007"
     CDS             complement(590..1024)
                     /locus_tag="ACGXWR_002007"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFK0803557.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1256..1966)
                     /locus_tag="ACGXWR_002008"
     CDS             complement(1256..1966)
                     /locus_tag="ACGXWR_002008"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFK0803558.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(1956..2816)
                     /locus_tag="ACGXWR_002009"
     CDS             complement(1956..2816)
                     /locus_tag="ACGXWR_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HFK0803559.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(2821..3459)
                     /locus_tag="ACGXWR_002010"
     CDS             complement(2821..3459)
                     /locus_tag="ACGXWR_002010"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HFK0803560.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3474..3773)
                     /locus_tag="ACGXWR_002011"
     CDS             complement(3474..3773)
                     /locus_tag="ACGXWR_002011"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFK0803561.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKEVTVIGIKNVMSAKEISEKFAETKWYQKNK"
     gene            complement(3816..5300)
                     /locus_tag="ACGXWR_002012"
     CDS             complement(3816..5300)
                     /locus_tag="ACGXWR_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFK0803562.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPEGYFLIVEDYDTYAEKQRV"
     gene            complement(5320..5781)
                     /locus_tag="ACGXWR_002013"
     CDS             complement(5320..5781)
                     /locus_tag="ACGXWR_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFK0803563.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGEDEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(5799..6866)
                     /gene="ulaG"
                     /locus_tag="ACGXWR_002014"
     CDS             complement(5799..6866)
                     /gene="ulaG"
                     /locus_tag="ACGXWR_002014"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HFK0803564.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADSKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7084..7854
                     /locus_tag="ACGXWR_002015"
     CDS             7084..7854
                     /locus_tag="ACGXWR_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFK0803565.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8127..8954)
                     /locus_tag="ACGXWR_002016"
     CDS             complement(8127..8954)
                     /locus_tag="ACGXWR_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0803566.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTEIDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9521..10756
                     /locus_tag="ACGXWR_002017"
     CDS             9521..10756
                     /locus_tag="ACGXWR_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFK0803567.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(11755..12015)
                     /locus_tag="ACGXWR_002018"
     CDS             complement(11755..12015)
                     /locus_tag="ACGXWR_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFK0803568.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12042..13343)
                     /locus_tag="ACGXWR_002019"
     CDS             complement(12042..13343)
                     /locus_tag="ACGXWR_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFK0803569.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEKAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNATLLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPMIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(13635..14093)
                     /locus_tag="ACGXWR_002020"
     CDS             complement(13635..14093)
                     /locus_tag="ACGXWR_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFK0803570.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14106..14936)
                     /locus_tag="ACGXWR_002021"
     CDS             complement(14106..14936)
                     /locus_tag="ACGXWR_002021"
                     /inference="COORDINATES: protein motif:HMM:NF023401.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HFK0803571.1"
                     /translation="MINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYD
                     KELQREIMPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYY
                     LYPDMVVEHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDI
                     AISLLNDDRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVETITLRKPISDFHKGL
                     MEAQVAAEKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK
                     "
     gene            complement(14949..15436)
                     /locus_tag="ACGXWR_002022"
                     /pseudo
     CDS             complement(14949..15436)
                     /locus_tag="ACGXWR_002022"
                     /inference="COORDINATES: protein motif:HMM:NF014148.4"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
     gene            complement(15447..16889)
                     /locus_tag="ACGXWR_002023"
     CDS             complement(15447..16889)
                     /locus_tag="ACGXWR_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFK0803572.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAIFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(16876..17640)
                     /locus_tag="ACGXWR_002024"
     CDS             complement(16876..17640)
                     /locus_tag="ACGXWR_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HFK0803573.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(17744..18619)
                     /locus_tag="ACGXWR_002025"
     CDS             complement(17744..18619)
                     /locus_tag="ACGXWR_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFK0803574.1"
                     /translation="MKESASCFVLSYSGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAIEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(18874..18958)
                     /locus_tag="ACGXWR_002026"
     tRNA            complement(18874..18958)
                     /locus_tag="ACGXWR_002026"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18922..18924),aa:Leu,seq:caa)
     gene            complement(18976..19047)
                     /locus_tag="ACGXWR_002027"
     tRNA            complement(18976..19047)
                     /locus_tag="ACGXWR_002027"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19013..19015),aa:Gln,seq:ttg)
     gene            complement(19057..19129)
                     /locus_tag="ACGXWR_002028"
     tRNA            complement(19057..19129)
                     /locus_tag="ACGXWR_002028"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19094..19096),aa:His,seq:gtg)
     gene            complement(19191..19275)
                     /locus_tag="ACGXWR_002029"
     tRNA            complement(19191..19275)
                     /locus_tag="ACGXWR_002029"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19239..19241),aa:Leu,seq:caa)
     gene            complement(19296..19366)
                     /locus_tag="ACGXWR_002030"
     tRNA            complement(19296..19366)
                     /locus_tag="ACGXWR_002030"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19332..19334),aa:Cys,seq:gca)
     gene            complement(19412..19483)
                     /locus_tag="ACGXWR_002031"
     tRNA            complement(19412..19483)
                     /locus_tag="ACGXWR_002031"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19449..19451),aa:Gln,seq:ttg)
     gene            complement(19495..19567)
                     /locus_tag="ACGXWR_002032"
     tRNA            complement(19495..19567)
                     /locus_tag="ACGXWR_002032"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19532..19534),aa:His,seq:gtg)
     gene            complement(19570..19643)
                     /locus_tag="ACGXWR_002033"
     tRNA            complement(19570..19643)
                     /locus_tag="ACGXWR_002033"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19609..19611),aa:Trp,seq:cca)
     gene            complement(19650..19730)
                     /locus_tag="ACGXWR_002034"
     tRNA            complement(19650..19730)
                     /locus_tag="ACGXWR_002034"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19694..19696),aa:Tyr,seq:gta)
     gene            complement(19732..19807)
                     /locus_tag="ACGXWR_002035"
     tRNA            complement(19732..19807)
                     /locus_tag="ACGXWR_002035"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19772..19774),aa:Phe,seq:gaa)
     gene            complement(19843..19915)
                     /locus_tag="ACGXWR_002036"
     tRNA            complement(19843..19915)
                     /locus_tag="ACGXWR_002036"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19880..19882),aa:Asp,seq:gtc)
     gene            complement(19925..19997)
                     /locus_tag="ACGXWR_002037"
     tRNA            complement(19925..19997)
                     /locus_tag="ACGXWR_002037"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19962..19964),aa:Val,seq:tac)
     gene            complement(20013..20084)
                     /locus_tag="ACGXWR_002038"
     tRNA            complement(20013..20084)
                     /locus_tag="ACGXWR_002038"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20049..20051),aa:Glu,seq:ttc)
     gene            complement(20099..20187)
                     /locus_tag="ACGXWR_002039"
     tRNA            complement(20099..20187)
                     /locus_tag="ACGXWR_002039"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20151..20153),aa:Ser,seq:gga)
     gene            complement(20227..20300)
                     /locus_tag="ACGXWR_002040"
     tRNA            complement(20227..20300)
                     /locus_tag="ACGXWR_002040"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20264..20266),aa:Asn,seq:gtt)
BASE COUNT         6364 a         4286 c         3226 g         6431 t
ORIGIN      
        1 agacgcagtg ttgacaattg aaaaaaaata aatgtttgta taccatatga ttatttcaat
       61 atgtatcctg gaattggaga tctcgtagag ctatatcaag atgaatcaaa tatacttgtc
      121 attcatcatg aaatatagag acttataaaa ttgtttattt ttataatgta tcagtataga
      181 aaggaaataa aacatggatt atactgttga atttgacagt gaactactta agcaatttcc
      241 acaagaagaa catttcatgt ataaagaagc aatttcccac aaagtgacag agtatttgga
      301 gcataatttt tttcgtataa agccagtgcg tactcgttcg gcaaaaggaa tatacgagat
      361 gaaagtcaaa attaataaaa aaaattatcg catagcattt gctttaaaaa aaaatcatgt
      421 gttcattttt tatattagtt cgaatttgca aaaaattgta tttgataaag aggtgagtaa
      481 aaaaataaaa tagctgagca ttggaggata gattgagtga tactaagtct atcctcttgt
      541 ttttctaaag aactaagcta gaattttttc ttttgtacgt tattatatgt tatttgtcat
      601 taccaaaaag cacctttttt cttctagtat ctatgacata agaaatacca cccatttcct
      661 ttacttgaac aaatcctact gattcataaa atttttttgt tttctcagta tcatctgtca
      721 ataattcgat ttggactggt ccataactag tgatcttctc caaagcttca ttcaaaagca
      781 ctttgcctat tccttggcgc tgatacctcg gatgaatgag gatatcttga ataaatgcga
      841 tcgtcgcaaa atcagtgatc caacgaacga ttccgataat cttcccttcc ccattacgct
      901 ttatcagaga ttcagattgt tcaaatgctc tagctaacct tgcagtgtct tttgtgtaat
      961 tcgtccaacc aacgctctta tataattcag aaatctcatc gatcataagg gaatcaatat
     1021 tcattttttt cttcctttct tatacaattc tccctctaat aatacagttc tttgactatt
     1081 taatctatca catataactc tcctgtaaag attctctcga ttccttaaaa tctctctttc
     1141 cttttagaat gcatcctttt tgataaataa aaaggttgtg ataaattttc ttcacaacct
     1201 ctgtttctct ctatcaagtg ttatctttta attttctacc cttaccctag catctctatt
     1261 gcccgtagta tgcatacttt ccatgtttgc gaaaataatg tttatctagt aaatattgcg
     1321 ggatttcaca tatattgggg ttgatcagct cgttttcttt ggccatcaga caaatttcat
     1381 ctaagatcaa actgttttct actgctttca taggtgaatc cccccatgtg aacggtccat
     1441 gtccatagac aagtactcca gggacttcgt ttggatctaa ttttctttcc ttaaacgtct
     1501 cgacaatcac attccctgta tgaacttcgt aagcttctct tacttcttct ttcgttaatt
     1561 ggcgtgtaca aggaacctta ccataaaaag catcagcatg agtcgtgcca taagctggca
     1621 aatcgcgtcc tgcttgcgcc cacatgacgg agtgcgtgga atgagtatga gtaatagcag
     1681 ttatatcttc aaaagtttga tacaaaacaa catgtgtggg gagatctgaa gatggtttta
     1741 agctatcttc ttctattata tttcccgaca aatctgttac caccatttga tctgcttgca
     1801 tgcattcata tctgacaccg cttggcttaa tgacgatgac tcctagctca cggtccactt
     1861 cactcacatt gccccaagtc aatttgacta atccgtatcg cggcaatgcc agatttgctt
     1921 caaggacacg ttgcttcatt gctgcaattt tttcttcaca agacatcata gccagcctcc
     1981 ttcaatttag aacttaagta gtcttttgcc tgctggattt ctcttcgaaa gtcttggctt
     2041 ttttcactcc acatttcaat cagaaatgtt ccatcataat ctagacgttt caaatgtctt
     2101 aataatccaa gaaaatcaac acaaccgcta ccaaaaggaa catcacgaaa ctggcctgaa
     2161 tattcttttg ttacagggta agtatctttt aagtggatag cagtgatata atcgatccct
     2221 ttctcaagtt ctcgagccgg attattttcc ggccatgcgg acaaattgcc taggtctgga
     2281 tatacttgta gaaaagggga atgaatctgt tctttgattt ctaaaaattt tgaaatggag
     2341 ttcataaatg gatcatccat gatttccacg gaaagaatga tgccatattt agaagcttcc
     2401 tttacgcttt cttttattcc ttcgataaag tcttctctgg aattcattga tttctcttca
     2461 taataaacat cgtatccagc tatttggatt actttgacgc ttagattatg cgccaaatgg
     2521 attgcttttt tcattagttg tttcgctgct tttttctttt ctggatcagc agaaccaaac
     2581 ggaaatcgcc gatgcgcact taaacaaatc gaatggatac gtacaccgga gctgaacatc
     2641 tcttctctca gctcagctat cttttcttca gaccaatcta atcgtgctaa ccgctcatcc
     2701 gtctcatcaa tcgacatctc gataaaatcg aagtccattt cttttacaag ggaaaaacgt
     2761 tctttccatg aaatatcttt gggtaatgct ttttcataaa tcccaatttg agccatttcc
     2821 ttacccccag atacgaatga tctcatcttt gaagttttgt gcggccttca tcggatcatt
     2881 tgctgctgta ataccacgac cagtgataaa ggtatacaca tcgatccctt caaataagtg
     2941 taatgtgtgt ggatttaatc caccagttac agaaacatta aagcctagtt caatcagttt
     3001 tttgatcttc gataaatctt tttcacccca agtttcacca gataacagcg catcacggct
     3061 ttgatggtag attacctgcc ggataccgat gttatgccaa tccatggctt gttcaaaagt
     3121 ccaattgccg tagagttcta cttgcaattc acctatttct ttttgtgctg cctccatagt
     3181 tggaatcgtt gcacaacaaa tgactgtcat ccagtctgct cctgcttttg caacattact
     3241 cgccactgtt cctccagcgt ctgcacattt cgtatcagcg actagttttt tatctgggaa
     3301 catactgcga atacagcgaa tcgctttttg tccttcctgt aagcaaagaa ttgtgcccac
     3361 ttcaataata tctactacat caccaacttt cataacatct cctaatgcat gttctaagtc
     3421 attgtgatct aacgcaattt gcaaattcgg cctgctcatc ttagttcctt cctttacttg
     3481 tttttttggt accactttgt ttcagcaaat ttttcactga tttctttggc tgacatcaca
     3541 tttttgatac cgataactgt aacttctttt ttctctgcct gagtaaacat attcaaaaaa
     3601 ttgactggcg taaaaactac atcgtattgg ccagctgaac tttttccctc tgaaatggca
     3661 caatgatgga ttttggtaat tggtacgttt agttctttca ttgctttttc cacacttctc
     3721 atcatcatca agcttgttcc tgatccattt gcacacgata ctaaaattct catcttaatc
     3781 cctccattat gagtgttgtc taatcagatt ttcttttata ctctctgctt ttctgcatat
     3841 gtgtcatagt cttctacaat caaaaaataa ccctcaggat ttttccgata ttgtaactgc
     3901 ggaatagcca ataaaccaat gacaactacg gcaattccag cataacctag gactttcatg
     3961 attactgtaa acaatggcca agctgttgcc cagtcgaaca tcccgatata accaccatat
     4021 gttgacatcc caatccatgt agcgaataat gctgaaccgc ctacttgtat gattcctgaa
     4081 agaaacggga acaggcaagc ggctttgaat ccacctcggt tattggcata aactgctata
     4141 acggcattat caaagaacaa cggaatgaaa ccggctatga cgatcgttgg tgatttcaat
     4201 aaaatcagta aaccaatcat caaaaactgt cccaaagcac caaacaagaa cccaatcgtt
     4261 accgcatttg gcgaaccaaa gccaaaagta gcagctacgt caattcctgg aacagctcct
     4321 ggtaaaattg tgtttgagat tccttggaaa gattgagtta gttcatcgac gaatgtccga
     4381 acacctaatt gcaagatcgc cagatatacc gcaaaattta aagaagtcgt cataatgtag
     4441 aataagaaac tctgtccttc ttgcatgaat tgcgcttgaa tcaaataatc tttgcctagt
     4501 acaatcagaa tgatcccaaa gaaaaatagc atgagtaacg aagtagcaac catattctca
     4561 ttgaaaatcg acaagaatcc tggtaatttg atatcttcga tttttttgtc ttgcttgatt
     4621 gatctatttt tcttttcatc ccgctttttc atccactcag ctaattttgc aaatataaag
     4681 attccgaaca tttgctgatg tgccactgca aatccggcac cttctgtcaa ttcctgcgtg
     4741 attcctactg ttaagttaga agctactgcc caataacaac ctaaaatcag tcccataaaa
     4801 atcaatactt gtatcctacc tagatcagga aagcaaaaca gtaaaatcca aaaagcggta
     4861 gctgcttgtt gaacctgaac gtttccggta gtgaaaacgg aacgcagttt cgtatatttc
     4921 tgaaaacgga ctaataagat atttaaaaca aatgcaatca gtaataaaat catcacatct
     4981 ccaaaggtac ggccaaatgt ctccattaat ccagcatcca cagcattttg tccaaaataa
     5041 ggatctgtaa ccatggcatc caaattgaac cgttccttta gtccaaccaa aatcggccga
     5101 aaattattga ccaaaccacc agagccaaca gtcaaaataa agtaaccgac cgttgccttt
     5161 aagaatccag cgatgcattc atgaagcggg cgtttcagca aaatatagcc taataacacg
     5221 ataaaaccaa tcaggtatgc tggctgcgtc aagatatttg ttgcaaaata cgtccaaatg
     5281 cttaacaaaa attcccccat cttttttctc ctctatcaat taattatatt ctgccatcac
     5341 aacttggtaa tcatcgatgg agttcgtaga gatgagacgc tcaaccaatc catctgtcat
     5401 taataattcg gataattttt ggatattttc tagatgttct tctggatctt ttgctgcaag
     5461 tgtaaaaaac aaactagccg ttttctcctc atcctcccct tcactttcaa aacggattgg
     5521 ctgtttcaac ttggtaaatg aaatagctgt tccaaaaaca ccatcacttt tttctgaaga
     5581 atgcggcatt gctacttgag gtgcgatcac aatataagga ccgtattttt ctacacaatg
     5641 gatgatctcc tccacatacg tttcatcaat aatttcctta tcgatcaata caagacagct
     5701 ttcggcgata gcttcacgcc aatccgtgat ttctttatct gggtaatgaa tcaattgatg
     5761 gtcaaaaaag tatttcagca agaaactccc cttctttctt ataaaaacga cggaaacggt
     5821 gtatcatttt caatcgagaa gacatcttca aatcctcgat aaaaattaaa ctcaagatca
     5881 tctttgtttg tcggatagat gaatttcccg cctacttgcc agatataagg tttaaatcca
     5941 tacttcaggc gatccttttt gaatttccaa atttcagtga tctcttttga atcagccata
     6001 aaattagacc aaatatcgta gtggacagga atcactactt ttgcattcaa tgactccgcc
     6061 atgcgcagca tatcaacaga agtaactttg tctgttatcc ctcgtgggtt ttcaccatag
     6121 gcccctaaac agacatcgat tttgtgttca ttaccatgtt tggcaaataa attggagtaa
     6181 tgtgaatctc ctgcatgata aagattccct cctgatgttt cgaataaata gtttactgca
     6241 atttgatcca tctcctgagg catttttcct tttaatacct cttctggatc ttcacaagtg
     6301 accaacgctg tccgatcaaa cgcttctaaa gctactacat tgatgtcttt gattttgact
     6361 gcatcacctg gctttactgt aatcgttttt tcttcaggaa ttccccattt ttgccacgtg
     6421 cgaaccactt cttttggccc aatgaatgtt gcttcaggac aattttgatg aactgctgcg
     6481 gctgtatgga tatctagatg atcggaatgg atatgtgtaa cgattaaagc gtctacattt
     6541 tttatcgcaa aaggatcgat tacgaaaggc tgagtacgta aattaggctg catattttga
     6601 acgccactca tacgcatcat ctgatggcct tttttcatca tgccattccc atgactacgt
     6661 tttcccgtcc cacaccatag atcacataaa atattcgttc cttcatgact tttcagccaa
     6721 attcccgtac agcccagcca ccacatagca aaagttccag gatccactac ttctgtttcg
     6781 atttcttcat tcaagtatgt gccccactca ggaaatgttt ctactaacca cttttctttt
     6841 gttacttcat tgacagtttt actcatttgc ttgctccccc catatcgttg ttccaactta
     6901 caagtaaata ttaatgtgta tcagcatcca tggaaaccct tttatatgac cgtttgtttt
     6961 ttatatgatt ttctttcagt aatcaatgat tgtttcagta taataaagac agatatgaat
     7021 gtttaaatga acaactagtc aaataaatcc atggatcaag atgtccctca ggaggcaaaa
     7081 gtcatgaaaa actcacttgt caatattgaa aaacgtcaaa aagaaatttt ggaactgctt
     7141 cagcagactg aacaactatc aactttcgaa ttagctgaat cccttgatgt atctattagt
     7201 acgatacgaa gagatttaaa tttattagaa gaaaaaaacg agatcatacg caattacggt
     7261 tattgttctt ataattacaa aaaccagact gattttgatc aatctggtcc tgaaaggatt
     7321 aaacaagcga ttgccagaga agctagtaaa tacattaacg attatgatac gctgtttatc
     7381 aattctagct cgactgcgtt gaaaacactg gattttcttc aatctaacca tttgacagtc
     7441 attacaaaca acgtgaaaat caattactct ccgcacaaag ataattgtag ttatatttta
     7501 actggtggag agatgcgctt tccaaaagaa gcactagtgg gcgacatcgc attaaatacg
     7561 atttcttcag tcaatgcaga catttgtatc attggctgta gcggagtcga tgtagtacat
     7621 ggggtcacaa caaagatatt aaatgaatca acgatcaacg aaatgatggt caacaagaca
     7681 atcaaatgta agattttagt cgctgatcat cgaaaaatcg gactgacatc aaagttcaag
     7741 attgctgata tttcagtctt tgattatttg atcactgata aattttgttc tgaaaaagta
     7801 ttagaggaga tcagaaatac ggggataaaa accattcaag tagattcatt ttaagaacca
     7861 ggacgtaaat atgtaaatag gattatcaaa aaaatgaata acaaatttat cgataaatga
     7921 aaaacacgct acgctcaaat tgataaagga atcccaagat gtgtccatcc aatcgatacc
     7981 atcataatct attgcttctt ttataaccgt tatatgttgc ctaaatagga atcaaacaat
     8041 atcgaaaaaa ggaggtatga caaaagtcac acctcctttt ttcgaataaa cggtattcaa
     8101 atcagaacac tgatttcaca accactttat ttcaggtcgt tttcaatcac ctttaccgcg
     8161 taatcatttc cgttgaaacg cgctattttt tttgcgtcca tatatctttc taaataatca
     8221 tcttctccta attgcttatg gcaagaagca atttcataaa gcaagtattc caatgcataa
     8281 gtcgatttat gtttcttatt atactcaata cccttctcac ataattggat tgctttatca
     8341 taatcctcga ttttacggta ataggtggcg atatcataat atacaatgca gaccatcaga
     8401 ttatcaaaat cagtctcact caatatttta agtgtacgct ccacataaac tttcgcaaaa
     8461 tctaattctc cttttgacaa gtagatcatt gccacgtttg cagctgcttg taagtgatgg
     8521 atatctattt cggtcgtttg ttccaacact tgattaaaat aaaataatgc tgcatctggt
     8581 tttttcgcat aaagatgatc aagcagtcct tgataaaata aaatttgatt taaaagatca
     8641 gaattactta ctttttcctg atcgatcgtt tgtaaaattt tataagattc ttggtatttt
     8701 gatacagaat tcaatgattg aatctcattt atttttttcc tgattttgtc ttcttctgtt
     8761 tctactaata tatcggagat ctcgacattc agctttttgc aaagcgcact taagatattg
     8821 atgcctggcg acatattctt gttttcgata ttgctgacag ttgcttgttc acaaatgcct
     8881 tctgctaatt gtacttgtgt taaccccttt ttctttcggt attcttttag taatgctcca
     8941 tctactttaa tcaaaacaat ttccttccct ttaaaaaatt atttctcctt tatatcatac
     9001 acaaaaaaaa gttctaaaca accaaaaatg tttagaacag aataaaaatt ttaattttaa
     9061 aataatattc aaattaaaca actggcgtat ctgctccttg atttcttttt gtgttatctg
     9121 aataattatc gtttacagtt ataacacata gtgaaaattg tcatggcgag aaagtctaag
     9181 aatattttta aacataacta tttctttctt acgtgtgtat aatgacgaca gcacacctat
     9241 caattaatat aattatttta ttttttatgt tctcatgttt atttttaatg acacaacttc
     9301 tcgtatttat ctggcacaac atataaatcg atcaaaaaat tgttgcgtgt ttttttgaaa
     9361 attggagttt caacttgatt acaaaattta aatttagaag ttgtgaaaac agcgagagac
     9421 agtttaatat tcaaaatata cataggctac tcgaacgctg tgttttttag tatactagta
     9481 agaaacgaag ggatagactc attccaataa ggaggatttc atgaagacaa ttctttttgc
     9541 tcctgcagta ttcaatttag ctgagacaac acgaatgatt gaggttgcca aagctatgaa
     9601 agaccgttat tactgtgtat tctttggctt ttctaaaact tttgctcctt tgatcacaga
     9661 aagtggcttt gagtatcatt tactagcgcc gatccttacg aaaaaacaag aagaacaaat
     9721 cataaaattt gaccagttgc gtacacttaa aaaccctttt accaaagaaa tggttgcctc
     9781 tcgtatcact agtgaacaga gtctgattgc taagtttgag cctcgactga ttgtgacagg
     9841 ttcgaatgtg acaatttttt tatcggcccg caataaaaag attcctttag tatatgttaa
     9901 accctatgct ttgagtgaac ctttttttca atcagagcat gcgctgatgc cccacgagtt
     9961 acgtttcttc ggccctttaa gcaatcccct ttggcactgg acaaaaaagc gtatagtaaa
    10021 tacccgatgg atccccaatg ccttcaaaca cgctgcacaa aaagaaatgc ttcctttacc
    10081 aaaaacaagt ttacaaatga tggatgctga tctaaatctc atcacaacgc ctaaactatt
    10141 tttggaagaa gaacagctgc cggaaaatta tcgaatcgtt ggtccaattt ttgctaagct
    10201 cagtacttcc ttgcctgaag aagtgctaac ttttatacag cgaaagcaac aagaaagaaa
    10261 acgtattatc tatttcgcaa tgggtagttc aggcaatccg cgtatgttac gcaaaatttt
    10321 gttcttctta caaaaacaac cggatctagc ggttattgca cctattgact atctgcttga
    10381 tgacattcaa tctgactcag aagatctttt aataacagaa tatctgtcta gtcatctttt
    10441 gcatgaattc attgattttt cttttatcca cggcggggaa gggaccgtcc aaactgcctg
    10501 tgaatccggc aaaccgttta tcggtgtggg gatgcaattt gagcaaagct gtaatattga
    10561 ctattgtgta aaatacggaa acgcaatcgc cctcacaaaa ccagtgactg aaagaaaact
    10621 gcagattgct ctgcgcgaag tttcttcacc caagattcgt cagcaggcac gcacgctgca
    10681 agccgttttt ccaataaatg gtccacaaca agcaattcaa gaaatcgaaa ccttcctgag
    10741 caaccaccca atatagtttc aagtagaaaa agctttttta atagagactc atcagtaatt
    10801 tcgctattcg agacccagac agtgaaaata caaaaaaagt aaatagtgga ttgaaaagtt
    10861 agagttactt aaattacggt gtctaaaaaa cacaaaatca tccttaaaat aaaagatctg
    10921 acgcaatcca aatgagcata ggtagcgtct gccatttatt cttagtcaaa ttctttgaca
    10981 cctttctctg gttggatcat ctcaacgttt cttcaaaaga aagaccataa taattaggca
    11041 aatacatttt cttaaaatgt gtcatataga tctagaagca tcgctttgta gagatttgtg
    11101 ctgctagtcc cttcaacaat tactaaatca aatgtaggat ttaccacttt atctttgata
    11161 atcaacctcc ctcttctgtt gagacaatga tctcgcaatc cgatgcatac tcctatataa
    11221 actgccagca atccccacat gctgagtaga tcatgtcaga atgttctatg tcgtcagcaa
    11281 cgataaacta aaagtcacgt tcaccatgac tgattgctat tcccagcgca attatttcta
    11341 tacacgtttc atgatttgaa taaacactct catcatacat attaccattc atacaccata
    11401 ctgcagcccc tactatatgg ttgtaagctc ccaaatctat atttgccttg atcactttgg
    11461 tagtagatcg actaattctt aatccattgc tgataaaatt ttcatttttg cctccttctt
    11521 tctgccaaaa cagttaaaac aataataatc tttatgtaaa aaagggctgt gacaaaagcc
    11581 ttgtcacagt cccatattcc gaataaacgg tggtcaaaag cttgcatctg cggtaataag
    11641 ttcaaccaaa cgaaaaataa gccaacattt cacaaaaatt taagaagcaa ttttcgtaaa
    11701 tttcttctta tttcttgaag ctaaccactt ctgtcacaac cacttttaga acatttaaag
    11761 cttcgatgtg acaaaccatc tatgctgctc gatcataaaa ttgatagcaa aaattccaca
    11821 aagtacatat gtcccccatg aaaacaaaac attcatatgc ggtacaatga tctttggaag
    11881 aatcacgatc aaaaatgatg ccagtgccca aatccatcga ttgatttgaa tatgatatgt
    11941 agctagcata ttcaatataa ggtgactagc cgttaataaa aagataaaaa caaaaaataa
    12001 aatcagccaa tacattgttt cccaccttct aaaaaccaaa cttagacagt ttggacttcg
    12061 ttttctccac gactttgttc atctgacagc atctttttat cataagcttt tacaaatgga
    12121 taatagataa taaatgctat caatgtgttg atcatgatca agataacaac acgccagtca
    12181 tttcctgctg aaagataacc gccgattgga gctggtaatg tccaagttgg caaaacagta
    12241 aatctattga ccatttctaa tttgactgca aaataactga taatagtcaa aactaaagga
    12301 actaagttga acgggatgaa catgtaagga ttcaacatca taggagctcc aaaaatcatg
    12361 ggctcattga tattgaagat accaggaata atagaaaaac gaccaacctc tttcaagaat
    12421 tttgatttac agaagaatat aaacaaaaca gataccacga tcgttgctcc tgcaccacca
    12481 attgttaccg tccattgata aaactgttca ggagcgatat agggtaattg ggtggcagct
    12541 gtaccatctg ccaatgcctt tgcattctca tccaacatga tcagccacat tggacgaaca
    12601 acagccccta caatactcat gccatggata ccaaatgacc acaacaaatg gatcaaaaac
    12661 attggtagta aaacaccaag caaattattc cctaaaatat tggttaaagg ctcgaataac
    12721 gataataagg tagcgtttac atcaaagccc gcgacgcttc gaatcagcca agtaattgtt
    12781 aaaatgactg cacctggaat caatgcctca aaactacggg caacagcagg tggcacttgt
    12841 tctggcattt tgatagtaat atttcgattt ttaaagaaac gatatacttc cactgcaaaa
    12901 atcatagata agatccccgc aaacatccca gatgctccca aagaactcat aggtaagacc
    12961 cagccaagag gtgccttttc aggagttaaa acgtttacag gaacttgtaa cataaagaac
    13021 gttcctaaag ataatatacc acctgtcaca ctatctaatc catatgattt agctagatcc
    13081 gaacccataa caaaagttgc ataaatagcc atcaatccca tcgtcatcct aaaaggtaaa
    13141 acaatcgttg ccgaataagg ggcaataaat tcattccatc caggaaacgg taaattgata
    13201 aagaccataa aaaatgtccc aatcaaaatc aatgacaatg ttgaaacaac cccattacga
    13261 attgctaata aatgacgctg tgtaccaatt tttgccattg gtgggacaag tttctcttcg
    13321 acccatttca tcagcttttc cactaaaacc actccttttc aataaaatat gaaccattca
    13381 ttgcatgaca acgcaaagaa tgttcataac taattatata attaagaaat tttatttcaa
    13441 tatattctct taaataatca aatttatttt taagaatcct gaaaataagt tttctaaatc
    13501 ataggagcaa caaaaaaatt cgataattaa caaaaatcaa aatgattaaa tctagtgatt
    13561 gaaacttatc atttcaaaaa aattttgtaa attcacccat aaatatcacc ctatttaact
    13621 tttttcatcg tacactaaaa ttcaaaacaa ctatctttaa tctttacttc ttggttttgt
    13681 tttaataaat ttccttcaaa aatgcctgga gaaactacaa tgatcaccgt atctttttgt
    13741 gcttgctcca acttcttcaa atctataata gctaacagtg tcccttcttt tacctcctgg
    13801 ttactttcaa cccgtatctg aaacggactt ccttcgagtt caactgtatc taaacccata
    13861 tggatcagta tttttctgcc agattcactt tcgatcgtta tggcatgtcg ggtaggaaat
    13921 atattatcga ttattccttt aactggcgca tggatatatc catcatgatt cgttatagcg
    13981 tatccaactc ctatcatttt tgaagaaaag acctcgtctt ttactgctgt taatggaata
    14041 atttgaccac tagctacagc ttttagaatg tttcttgttt taaagaaatg cactttttat
    14101 cacctctact ttaatgctgg ccaatatttt ttgtttactt tgatcatttc atctagtatt
    14161 ttttttgcga ctctggcatt tggtacggtt tgattcaatg taaatgcttg taaagctttt
    14221 tgataagaac cttcaaagta agcatctact agtaacttct ctgctgcaac ttgtgcctcc
    14281 atcaatcctt tatgaaaatc actgattggt tttcttagtg taattgtctc cacaccagtt
    14341 gcaccaacat atgccggtat ttcaacaact gcatctgacc gtagattcgg aatcgcccct
    14401 tgattaggaa cgattagcat aaagcgacga cgatcatcat tcaacaagga aatagctata
    14461 tcgacgatat attgtccatg ctccccaaaa ttaaagttca atacttcttc cacaataccg
    14521 cggcgtattt tatcagccat ttctttggta tttttctctc gtccatccat gaccatatta
    14581 gcacgtgtat actctttgtc agtatgctca acgaccatat caggatataa gtaatactct
    14641 aagtaattat tcgggatatt acttggaaaa tttttcgtga tgactgacat catttgaaag
    14701 gttttttgcc aagttttgtc tcctatatta aaatcggcga cttgcatttc ttttgttatt
    14761 agtttttcaa taatctctgg cataatttct cgttgcaatt ctttatcata aatcgatgta
    14821 taccagccaa agtggtttaa accataatac gtaacgatcc aattcttacg atcataaccg
    14881 taattcactg caatcgtttc ttcaattgaa atagtcatat cacaggcatt aatcattttt
    14941 acattcggat atttacgacg aacagcttca gaaacgatcg actctggatt tgtataattc
    15001 aaaatccatg ctttgggggc atagtcttgt atatgatcga caatttccaa taaacctttg
    15061 attgagcgca tcccataagc aaatcctccg agtccacacg tttcctgtcc tactaatcca
    15121 tgtttaagtg gaatcttttc gtccttttct cgcatctcca atcctccaac acgaatttgt
    15181 gagaaaacaa aatcgcatcc tgtaaaagca agctttggat catccgttgc acgaatgcga
    15241 atatttgaaa aacctttttt ttcagcataa atttaacaat caagtacata tccatatttc
    15301 tttcttcatc aatatcatat aaacgtattt cagataatgg caaccgtttt tcattgttca
    15361 aaatggcttg aacgattcct ggtgtatacg tactcccgcc tccagctata gtgataatct
    15421 gttttttcat catcatcttt tcctttctat tcttctaata atttattgaa ttctgccata
    15481 acataagtca cttctaagcc gatgataatt tgataatttt tttcagttgg tttaatgatc
    15541 ccgcttatcc ctaattgctt gattcgctgt tcctcgacca tggtgggatc cactacctct
    15601 acccgtaggc gtgtattaca actatagaca tccaggatat tggcttttcc tccaaacgct
    15661 tgtagcattt ttgttgccat atattcataa tttttacttg ctaaccctaa ctctgtttct
    15721 tctaaggtta cttcattgcc aaactctgcc ttagcttcac gtcctaatgt ctgaatgttt
    15781 ctcttattga tcaaataata aaaagtaacg taatacaagg caaaaaagaa aattccgatt
    15841 ggaagaatca aaatagcatt ggtagcgatt cgaaaattga tgagataatc aacaatacat
    15901 gctccgaatg taaaaccaat tcgtatattg aataagtaac agacaatccc tgctaaaccg
    15961 gcaaaaagtg catggatcac gtacaacata ggagaaagaa acatgaaact aaattcaaca
    16021 ggctcagtga tatttgcaat aaatgaagtt cctgcaccgc ttcccatgat tcctttgacc
    16081 atctctttat tttctttata agctgcttta tagatagcta gacatatagc tggtatacca
    16141 aacatcatta ctacaaaaaa acctgataaa aacagtccag cctgaggatc tccgttgata
    16201 aagcgtgtca tctctcctct gaaaacttcc ttgctaggag atgtatagct tcctaaatcg
    16261 taataaatat acgtattcaa cacatggtgc agtccaaagg ggatcagcaa acgattcaaa
    16321 aacataaata tccccacacc taatgccccc atatcaacga gcagttttgc aaaattatca
    16381 atcccaattt ggatgagcgg ccagataaag cccaaaaaaa tagctgcgat tgtttgtaga
    16441 atcatcacca tagtcaatgg gaatttttcg cccgcaaaat aagaaaaaac tactggtaat
    16501 ttttgttctt taaagcgatt atacgtccat gccgctacta aaccggaaat aattccacca
    16561 aaaatcccca tattcacttc tgggtccatg atttctaagc cttttttcaa ggtagcaatc
    16621 gctaaaaaac cagtaagtgc aggtattcct ttgtccttat ttttgacaaa accgattgca
    16681 actcctatag caaataagat atccaagttt ccaaaaacgg catttccagc tgcaccaatt
    16741 actgggatgt tcagcatatc atcagctgat aaacgcatga tcaatcccgc taatggcatc
    16801 gctgcaactg gaagtagcat cgctcttcca agcttctgca catttgattt aacattcatt
    16861 tttattcctc ctctattaaa tatcctcata tgttactaac tcaatcaaag gatcattttt
    16921 cactttttga gcaaatgctg aatgaattaa aaattcgact tggtgagtac gaggatacac
    16981 aaaacttgaa ccatttaaca attcctgatc caaatacgct gcgtgacaca tgacttcgat
    17041 cgttttatct tctctcaata tcatgagtaa acttgccaaa tattcttcca cactcgtatt
    17101 gatttgtcgt tttttttcat cagtttctcc tacgacatcg aaacaaggct caaaataatc
    17161 gacatgacga acttcatctt ttcgttcaaa gttgctccga accggcaaat catatttttt
    17221 tgctaatgta acaactacct cctggttttc atccaaagta tgagtatgat gatgactgtc
    17281 taaatgagtt ggtatgatcc ccgcatgata aattttttga atctgagcat tccattcctg
    17341 atacagttga tctttgtcaa tgttaaatgg atgctgataa taagataagg atctgaactc
    17401 tccgctttcg ataagagtat cgacagtttt gagaagtggt ttgccacacg tcaatgttaa
    17461 atggactcct acacctagcc taggcatttc ctttcttagt ttcacagcgt gctcgaaacc
    17521 cggcatattt gccatcaatg tagttgatgt caaaattcct cgctgataag catccataat
    17581 cccataattc acaccatggc tatagccaaa atcatccgaa ttaaaaatca cttttcccat
    17641 ttcattctcc ttcttttttc tactaaaata ggcgcaacca aataatcata gtccatttac
    17701 tatgtgtcat ttggttgcgc ctatagatag ttacgccctt attttaatag attcgtgcta
    17761 gatgaattgc caaatagatg atttcatttt cttgaatggc aagttgaaat tgctgttcga
    17821 tgatatcttt aatctttagt gctgtacaat acgctttgct atgtttaaat gtttcagtaa
    17881 aaaaaccaat attttctact ggcgtttctt cctgataaat caagcgttta accaggaatt
    17941 tgatatgaac cattaagcga tgataagtca gtgattcttt atcataaacg tttgaatagg
    18001 atttttctag atgggacaaa atcgtggtcg tcatttctac tatttttaag ctctttaaac
    18061 tattaggctc tcctagctca gcattaatga tatgcatagt gatgaatcct acttcatttg
    18121 accctaactc ggtttgatat cgatgattga ttcgctcgac cacttctatt gctatatcat
    18181 attcatttgg ataaaggaat ctcatttctg gcaacataat tgctgtgaca tctctatctt
    18241 ctctttttcg ttgaatagca aaataaatat gatctgtcaa tgtaatatag atatttgaat
    18301 ctaatggaga ggagatccta gctgttatca gttcaatcac ttcttccgca aaatccataa
    18361 attcgattgg aatctgcgag actatctcac tgaatcgttt gatcttttct ttagaatcta
    18421 atacaaataa tttgtcagca tcctcaacat caaatggctt actcacttta gcagaaaagc
    18481 caatcccttt ccccatcgca attttttcta ttccatcgtc atcgatcaat acagcattat
    18541 gattcagctt tttcatcaca tacaccgtta attcacctcc actatatgat aaaacaaaac
    18601 aacttgcaga ctccttcata catatttttg tctccaaaca atttttaaag acaaaaaacg
    18661 acctaagaaa gaaccctttc ttaggtcgtg cctaattgaa tagtagcacc ctacataatt
    18721 tacaaaaata gtttaacaca taataaaagc gttatcaata tcttttttac tcgttttatg
    18781 ataatacttg tatcgaattg atttggaggt aattacataa aaacaaaaaa aatatagcaa
    18841 ctctctataa gaaagttgct atattgataa ttataccggc ggccggggtc gaaccggcac
    18901 gtcctcaacg gacactggat tttgagtcca gcgcgtctgc caattccgcc acgccggcaa
    18961 atttaaaaat aataactggg gtagctggat tcgaaccaac gcatgaggga gtcaaagtcc
    19021 cttgccttac cgcttggcta taccccaaga ataaagggcg aatgatggga atcgaaccca
    19081 cgaatgccgg agccacaatc cggtgcgtta accacttcgc cacattcgcc atcataaaag
    19141 atgttattta atttctcaat aaaaaactaa gatgaagaca tcttagtcaa taccggcggc
    19201 cggggtcgaa ccggcacgcc ctcaacgggc actggatttt gagtccagcg cgtctgccaa
    19261 ttccgccacg ccggcaagtt gatttattag tactaaggcg gtaaccggat ttgaaccggt
    19321 gatgaaggtt ttgcagacct ctgccttacc acttggctat accgccatta tactattatc
    19381 aatctacaaa ataaagaata aattatagaa actggggtag ctggattcga accaacgcat
    19441 gagggagtca aagtcccttg ccttaccgct tggctatacc ccaagaataa aaagggcgaa
    19501 tgatgggaat cgaacccacg aatgccggag ccacaatccg gtgcgttaac cacttcgcca
    19561 cattcgccat ggcaggggca gcaggaattg aacccacact aacggttttg gagaccgctg
    19621 ttctaccttt aaactatgcc cctataaaat ggaggagagt ggattcgaac cactgaaccc
    19681 taaggaacgg atttacagtc cgtcgcgttt agccacttcg ctactcctcc atggtggcgc
    19741 gggacagaat cgaactgccg acacacggag cttcaatccg ttgctctacc aactgagcta
    19801 ccgcgccata ttttaaaatt attaattgaa taacaagaac gacggttccg acgggaatcg
    19861 aacccgcgat ctcctgcgtg acaggcaggc atgttaaccc ctacaccacg gaaccagttc
    19921 attatggagg ttaacgggat cgaaccgctg accctctgct tgtaaggcag atgctctccc
    19981 agctgagcta aacctccaac attcaattaa aatgacccgt acgggattcg aacccgtgtt
    20041 accgccgtga aagggcggtg tcttaaccgc ttgaccaacg ggccaggtaa atttgctacg
    20101 gagagtaagg gattcgaacc cttgagacag tttgcaccat ctacatgatt tccaatcatg
    20161 ctccttcggc ctctcggaca actctccaga gtgaaagaag ctcaatactc tttctcaaaa
    20221 tgagaactcc ggcagtagga ctcgaaccta cgacatcatg attaacagtc atgcgctact
    20281 accaactgag ctatgccgga ataacat
//
LOCUS       DAYNVV010000050        18911 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.052, whole genome shotgun sequence.
ACCESSION   DAYNVV010000050 DAYNVV010000000
VERSION     DAYNVV010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18911
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.052"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(20..250)
                     /locus_tag="ACGXWR_002041"
     CDS             complement(20..250)
                     /locus_tag="ACGXWR_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803575.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(686..1252)
                     /locus_tag="ACGXWR_002042"
     CDS             complement(686..1252)
                     /locus_tag="ACGXWR_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFK0803576.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1252..2208)
                     /locus_tag="ACGXWR_002043"
     CDS             complement(1252..2208)
                     /locus_tag="ACGXWR_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HFK0803577.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2208..2864)
                     /locus_tag="ACGXWR_002044"
     CDS             complement(2208..2864)
                     /locus_tag="ACGXWR_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFK0803578.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3234..5252
                     /locus_tag="ACGXWR_002045"
     CDS             3234..5252
                     /locus_tag="ACGXWR_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFK0803579.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5322..5528
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5679..8093
                     /gene="leuS"
                     /locus_tag="ACGXWR_002046"
     CDS             5679..8093
                     /gene="leuS"
                     /locus_tag="ACGXWR_002046"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HFK0803580.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8441..9994
                     /locus_tag="ACGXWR_002047"
     CDS             8441..9994
                     /locus_tag="ACGXWR_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WD40/YVTN/BNR-like repeat-containing protein"
                     /protein_id="HFK0803581.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10375..12159)
                     /locus_tag="ACGXWR_002048"
     CDS             complement(10375..12159)
                     /locus_tag="ACGXWR_002048"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0803582.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12174..13895)
                     /locus_tag="ACGXWR_002049"
     CDS             complement(12174..13895)
                     /locus_tag="ACGXWR_002049"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0803583.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13995..14756
                     /locus_tag="ACGXWR_002050"
     CDS             13995..14756
                     /locus_tag="ACGXWR_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFK0803584.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15723..15991
                     /locus_tag="ACGXWR_002051"
                     /pseudo
     CDS             15723..15991
                     /locus_tag="ACGXWR_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16663..>18911
                     /locus_tag="ACGXWR_002052"
     CDS             16663..>18911
                     /locus_tag="ACGXWR_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFK0803585.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGE"
BASE COUNT         6213 a         3354 c         3790 g         5554 t
ORIGIN      
        1 tcattaaaaa gcataaccat tactccgatc tgtttttaaa attagtttct acctctaata
       61 tatatcgagt ttttattttg ccttcagaga atactgtttc tttttttgca gttacaggtt
      121 gtttattttc ggaaaaagct aatatagcta agattgaaac atccatctgg aatttatctt
      181 ttttactgct ttgatcataa aagtctgcat attcatcact gatatttttt ctaataaatt
      241 cttccatcat aaaaatcacc tcaaaacgat tatacgaact tacgttcttg ttgtaaagcg
      301 atatttgagg ggcaaaaaag gggcataatt tgactgatat taagttagct attgatatat
      361 gaatgacata caaaaatata aaatctttta aaaatgctta tatatcaatg tttttgccat
      421 tcttttatat atctgttata tgtcaaaaaa atgtgttcaa tttcaatttg tatttgaata
      481 aagaggttgt gaaaaagctg tcctgcatca agtaataaga acagccaatc aaaaacagct
      541 tctcatgttt ttgatttggt tggacttatt accgcagata taagcttttg agcaccgtga
      601 ataaagaggt tatgaaatca acgctctaac ctgagtatta gagaaaaaaa cgcaaaacat
      661 atcatttatg ttttgcgttt tttatttatc tttttttctc aatacaatat aaaataggcg
      721 gctggttctt ttggttgata aaccgataat tcagcacatt atatgtttcc tgtggcagtt
      781 tggaacaaaa agaatcaacc atatccagtt ctttttctcc accttcatga ccatagtaga
      841 cgacaaggat caatcgtccg cgaggcacaa gtcgtttcaa tatttcttcc atagctgtgc
      901 gtgtagtctc tggcatagtg atgattgctt tatcactttt tgggagatac cctagattga
      961 aaatccctgc tttgagattt tgttgttcag ctatcacttc tcctaacgtt tcgtggcctt
     1021 gtagaaacaa tgagacacgt tcttctaact gacgctgttc tagcctttca cgagtagcat
     1081 cgattgcttg ttgctggata tcaaaactat agacatgacc agtttttccg atgtgttctg
     1141 ctagaaaaac cgtatcgtgg ccattgccca tcgttgcatc tacgacgtga tcccctggtt
     1201 gcaagatttc ttgcagtaat gtatggctga aatgcaaagc agtttgcaac atcagacgct
     1261 cacctttttc cgtacatcat attttccttg gaagctatct ctgcgaagaa gttcttcatc
     1321 aattgcattc aagacttccc attttttcaa gctccacatt ggtccaatca aggaatccca
     1381 cggcgcatcc cctgtcaaac gatggatgat gatctctttt ggtatcattt ccagctggtc
     1441 gcaaatgaca ttgacatagt caggacggct cattaattga aggcgacctt catgatagtc
     1501 ccgcaacatt ctcgttttgc gcatcagatg catcaaatgg agcttgattc cttggatatc
     1561 tgaatctaaa atggtgcgtc tgacattttc tttcatcatt tctaaacttt cgcctggtaa
     1621 tccgttgatc aaatgcgtac aaacacggat attatgtttg cgtaatttag ccacgccatc
     1681 taaataagtt tgataatcat gtgctcggtt gatcagtttt gaagtttctt caaaagttgt
     1741 ttgcaatcca agttctaccc ataaatacat ccgctcgttc agttcagcaa ggtaatcaac
     1801 tacttcatct ggcagacaat ccggtcgtgt accgactgat aatcctacga cacctggtaa
     1861 attgactact tgctcaaatc gttctttgat tatttcaact ggcgcatggg tgtttgtaaa
     1921 attttggaaa taaacgatgt attgttggac atgaggccat ttttgatgca tcatgtcgat
     1981 ttctttctgg aattggattg gaagagggtc ttcaggtgca acgatcatgt ctcccgaacc
     2041 agatacactg caaaaagtac aaccgccatg ggcaacagtc ccatctcgat tcggacagtc
     2101 aaatcctcca tcgatcggca ccttgaaaat tttcccgcca aactcatttc gtaaagcgta
     2161 attccaagaa tgatatcttt tatttccttc tgaataagga aaagtcatta aaagtccttc
     2221 tttctgtaag agttatctat ttgttttctt ttttctctat acactggata agtcaggcac
     2281 agccaagaaa gactgagtaa gtagccgccg atgatatcag taggaaaatg aacgcccaga
     2341 taaatgcggc ttatcccgac acttactata ataaacatca tcagcaattg aagcaatgtg
     2401 cgtaaggttc ttttttgaac aaaagctgga agcagaaata gtaaagaacc gtaaagaatc
     2461 atactgcctg ctgcatgtcc actagggaaa ctgtaacttg tttcaactac taagtgcgcc
     2521 aatgaaggac gctctcgcat gaaaaatagt ttgatcaccg ggttgatgat tccagcaatt
     2581 acaataaatc cagaaacgaa ccaaaatgtt tctgcccttt ttttcttata ccacatccat
     2641 aaagccgcac aagcaaataa aatgatgacg gtaagaggat taccgaattt agtcataaag
     2701 agttggtagc tgttcagatc aggataagaa gctctgacaa tgcctgtaaa ccactgatcg
     2761 aaaccagaaa gccacgacag atggaacttt acgatccagc ccaaaatgaa aaacaggaca
     2821 agaaagaagc taccagccac ctgaaatgat gttttatatt tcatacaatt cctcctttga
     2881 agcaatgact tattatagca tttttggtcc agcgaaaaaa acggtaaaga gataaaacca
     2941 atgtatgatt cctctttgaa taaccaatat tcttataaaa aaaataactg taatcggaaa
     3001 gacatttttt ggtaatgcaa atgaaatgtt agggaaataa aatcagtgtt tttcgaaatc
     3061 cttttaaaca agaacgtaga cgtaggaaga acttgaaaat gaacagaagt tgttcattac
     3121 ggtaaattac aatatgatta caaaaaacaa caaagctctt aaataacttt taataaatat
     3181 taagagaagt tataattatt aataatagat aaattgaagt tggaggatag aagatggaaa
     3241 acattgcaag aaaagaacgg agacgtttag aacagaccaa acgttttcga aaagcaaaac
     3301 gaggggcagc aatcgtggga actgcgatgg taggctgttc tgtcgctgcc ccattagtac
     3361 agccggttcc tgttcaagcg gatgaaacac ctgttcagtt cggcgcaaga atcaatacag
     3421 cggcatttat cacagaaatt gctacttatg ctcaaccaat cgctcaagcc aacgatctat
     3481 atgcatcagt gatgatcgca caagcagttg tagaaagcgg ttggggcagt agtgcgttat
     3541 ctcaagcacc ttattataat ctttttggga taaaaggcag ctatcaagga caaaccgtct
     3601 acatggatac gcttgaattt ttaaataatc aatgggtaaa taaaaaggag cctttccgac
     3661 aatatccttc ttttgctgaa tctttcaatg acaatgccta tgtacttaga aatacttcat
     3721 ttggcaacgg ttattactat gccggtactt ggaagagcaa cacgaaatcc tatacagatg
     3781 cgacagcttg tttgacaggg cgttatgcga ctgatcctgg ttacgcaggc aaattaaata
     3841 atatcatcgc aacttacgga ttgacccaat atgatacacc agctagcgga aacgcaggcg
     3901 gtggagcgac tacaggtggc aataatactg gaagtgcagg tagtactggc ggttcaagca
     3961 attctggtaa tacaaactca ggttcagcaa cttcgaccac ttatactgtc caatctggtg
     4021 attctgtttg gggaatctca aataaattcg gtatcacaat ggatcaattg atccaatgga
     4081 acaacatcca aaacaatttc atttatccag gacaaaaact gacaatcaaa ggtagccagg
     4141 aaaatggctc ttcgacgaat aattccggta acaataccaa ctcttcagga aatgctggta
     4201 catcaaacgg aggacaaaca actggtgcga aatacactgt tcaatctggt gattctgttt
     4261 ggaagatctc aaatgatcac ggaattacga tggctcaatt gattgaatgg aacaatatca
     4321 agaacaattt cgtttatcca ggacaacagc taatcgtatc aaatggcggt tcttctaatg
     4381 ctggagcaaa tactggctca aatactggga atacaagtgg ctctagttcg tccagctcaa
     4441 gttcttctaa tacagcttca ggaacgaaat atacagttaa agccggagac tctgtttgga
     4501 gcgtctcaaa taaatacgga attacgatgg ctcagctaat ccaatggaac aatatccaaa
     4561 ataactttat ctacccagga caacaactga ctgtttcaaa cagtggatca acaaacagca
     4621 cgtcaggtaa tacaggttcg tcaaccaata caaataacag cagttcagtt aatactggca
     4681 gcagttcgtc tcaaggcact tataccgtga aagcaggtga atctgtttgg agcgtggcaa
     4741 ataaaaacgg catcacgatg gatcagttaa tcgaatggaa taatatcaaa aacaacttca
     4801 tttatccagg acagcaattg atcgttaaag gtggaacttc ggcaaataca aatacaggtt
     4861 caactacttc tgcagcgaaa ccaaatacac cgaatacgtc tgctacgaca agtacatcat
     4921 ccactggtaa tacgatgtat accgtgaaag cgggcgagtc agtttggagc gtagcgaaca
     4981 aacatcatat cacgatggat cagttaatcg aatggaataa tatcaaaaat aatttcatct
     5041 atccaggaca gcaagtgatt gtgaagaaag gttcatctca atcaacaaac caacaatcag
     5101 ttactggttc gaaaacctat actgtgaaat ctggagaatc tgtttggagt gttgctgaca
     5161 gtcatggaat tacaatggct caactaatcg aatggaacaa tattaagaac aactttattt
     5221 atccaggtca aacgttgatt gtagctaaat aaaatagctg ttcgaagaaa taacgattga
     5281 attccacaaa aatatttgtt actataaggc tacttaaata tgacaacact tgaaaaggaa
     5341 gtagtaaaaa gactgaagtt tcagagagcg catggctggt gagaatgtgc acggatgctt
     5401 ttgaactcgc ctttgagttg cccttgctga atacccgagt aagcaagcgg cggtgacggc
     5461 cgttacaacg ttcgaggcct tttcactaag gtaaaattag gtggtaccgc gtagattacg
     5521 tcctataaaa agagcaatct ttttatagga tttttttatt tcttttgtga agtttgagaa
     5581 aacaaagcaa aaggaaataa aaataaacag attctgccgg ttttttcgtt atatttataa
     5641 tagaaacaag tgttttcaat agaacaggag gacagcaaat gagttacaat cataaagaaa
     5701 ttgagaaaaa atggcaaaaa tactgggcaa aaacgaatac tttcaacacc catgatgatc
     5761 ctgaaaagcc aaaattttac gcactggata tgtttcccta tccatccggt caagggctac
     5821 atgtagggca tcctgaaggt tatacggcaa cggatatcct ttcacgtgtg aaaagaagtc
     5881 aaggatacaa cgtgctgcat ccaatggggt gggatgcatt cggtctgcct gctgaacaat
     5941 atgcgctaga tacaggaaac gatccagctg agtttaccca aaaaaatatc gaaacattcc
     6001 gacgccaaat caattcttta ggatttagtt atgactggaa tcgcgaagtg aatacaactg
     6061 atccggagta ttataaatgg acacaatgga tctttacgaa gctttatgaa aaaggtctag
     6121 cttatgaagc agaagtagcg gtaaactggg tacctgaatt aggaacagtt atttcaaatg
     6181 aagaagtgat cgatgggaaa agtgaacgtg gtggctatga tgtagtcaga aaaccaatgc
     6241 gccaatggat gctgaaaatc actgcttatg ctgatcgctt attggatgat ctagaattag
     6301 ttgattggcc agaaagcatt aaagaaatgc aaagaaattg gatcggtcgt tcagtaggag
     6361 caaatattga atttaaagtg gctggtacgg ataaatccta taccgtattt acgacacgac
     6421 cagatactct attcggtgca acttactcgg ttcttgcacc tgaactagat cttgttagag
     6481 aaattacgac ccctgaacaa aaagctgctg tagaagctta tatcgaagag acagctaaaa
     6541 aatcagatct aaagagaacg gatcttgcaa aagaaaaaac aggagtattt actggtgctt
     6601 atgcaatcaa tccagttaat ggcaaggaaa tcccaatctg gatcgccgat tatgtattat
     6661 cttcatacgg cacaggagcc atcatggctg ttccagcaca tgatgaacgt gactttgaat
     6721 tcgctcaaac tttcggacta gaaattcttc cagttatcga aggtggagat gttgaaaaag
     6781 ctgcttacac agaagatggt acgcacatca actctgaatt tctagacggc atgaacaaac
     6841 aagaagcaat cgataaaatg aatgaatggc tagaagaaaa tggcgtaggg aaaaaagaag
     6901 tcagctatcg cttacgtgac tggctattct cccgtcaacg ttactggggt gaaccaatcc
     6961 caatcatcca ttgggaggac ggaacagtca cagctgtccc agaagaagag ctaccattac
     7021 ggttgcctaa gacaaaaaac atcaagccaa gcggtactgg agaatctcca ttagcaaata
     7081 tcgaggagtg ggtcaatgtc gttgatcctg taacaggtaa aaaaggccgt cgcgaaacga
     7141 atacaatgcc acaatgggca ggaagctcat ggtattacct gcgttatatc gaccctcata
     7201 acaaaaaaga actagcagat tatgaaaagt tgaagcgttg gctaccagtt gacatctaca
     7261 ttggtggagc agaacatgcg gtacttcatt tactatatgc acgattctgg cataaattct
     7321 tatacgatat cggtgttgtt cctacaaaag aaccattcca aaaactatac aatcaaggaa
     7381 tgatcttagg cgaaaacaac gaaaaaatgt caaaatctcg tggtaatgta gtcaatcctg
     7441 atgatgtggt cgaaacttac ggtgcagata cactgcgcat gtacgaaatg ttcatggggc
     7501 cattagatgc ttcgattgct tggagcgaaa atggcttaga aggaagccgt aaattcttgg
     7561 atcgtgtatg gcgtttgatc gttgatgaga acaataaaat gcgtgaccgt atcactacat
     7621 tgaatgatgg caagcttgat aaagtgtatc atcaaacagt gaaaaaagtg acagaagact
     7681 atgaaaatct tcatttcaat acagcaatct cccaattgat ggtctttatc aatgaagcct
     7741 ataaagtgga cgctctgcct tatgaatata tcgaaggatt tgttcaacta ctcgcaccga
     7801 ttgctcctca catgggtgaa gaactatggg caatccttgg aaatgatggt ggtatttctt
     7861 acgcaccatg gccaacatac gatgaagcag cacttgttga agacgaagta gaagttgttt
     7921 tccaagtaaa cggtaaagtt cgtgcgaaaa gcaatgttcc ccgagactta ggaaaagatg
     7981 agctagaaaa agcagcatta gccaatgaaa tagtgcaaga atatattgaa ggcaaaacag
     8041 tcagaaaagt tattgcggta ccaaacaagt tagtcaatat cgttgctaat taattggctc
     8101 tttgtcaata aggactgatg agttgtgcaa aatcaaatct gggccagaat gaacttcatt
     8161 ctgtctcaga ttttttgtta tttcaaattg attaattgat tgatcaaaaa ggttttgatt
     8221 ttcatgttct caaacacgtt caatgtcttt ttcttctgaa tggtcttgta agagatctct
     8281 gtaatcatca aatttttgtc tattaatctt agtatttttt gatgtataaa ctacctgaaa
     8341 ttgagagtac ataccaaatt cataaatttt ttattagtgg gactagtgat tgtatggatt
     8401 ttgacgcata atgaatgaag tatgagaaaa ggagagacaa atggatcaag aactatttat
     8461 tatcgaagta ttatcagcta aacaaaaaat tatcgagaaa gcgaaaaaaa gagcgaaaag
     8521 aataatgttc aagcttttaa gcttagtatt tttctctggt ttgctttttt tcggagctgt
     8581 atcgttccta tatcgccata tgagtgcagt agtccgttca gctgaaggga tgcaaaaatt
     8641 aaataatttg tatcactttt cgtggggagt tggcggaata acaattgttg tgcttattgt
     8701 ttttcttcta cttatttggc tccgttacca tcaattgtcg cgtcatttcg atcaatggct
     8761 tagtcaaaga gcacaacagt ttttacataa taaaccaact tctcaagatg atgactatct
     8821 ttattttgag aagacttcga cgagtcaagc ttttcggata caaaaaagtg attgccagtt
     8881 attgctgaga tcacttgatg atttacctat ctacttaggc gaaagcaaat caaaattcgg
     8941 aatgaacaca ttccatattt ttttactaga aaacgaaccc agatgggaaa aaagccagtc
     9001 ttcgcctggt ggatacctga caactaagat gagtacatta gtcactggtt ttttcctcat
     9061 tcttttagct ggaacaatct attatgggag atacactcag ccaaaaatgt cttctcatat
     9121 aaatgctgct tctcacatga caatgaactc aactaacgat acgcatatac aaaagacaaa
     9181 tgaagggttg ttagctgatc ctaagcaaaa ggtaaatttg acaacacaaa agataaatga
     9241 tctcaaactt gatacagaga cgcactctct ctatatgaca acagatagtg gtgctaattg
     9301 ggtatttgtg ccgattgatt cgcaatggtt gcgttttggc gaatacaccc tgacaacggg
     9361 gctgattcct gaaggttatt ggatggacaa cacatatgat atttccgccg atttctcatg
     9421 gtttatctat tcttctgggg atgatgtacg tctgctgact tcaagagata atggtaaaac
     9481 atggcaaacg tctattatca cccaatcagt tcagccgata cgttatcgaa aagcggtatt
     9541 ttatggcaac gatggtctat ttatctgtac atcagccagt gggatgtctg cagaaacttt
     9601 gtacatttac actactatgg atggcggaat cacttggata aaaagtggaa gtacaatgat
     9661 caatcagcca gtacaaaatg tcagcttcgt tacaacttct ttaggttttg tttcgacacg
     9721 tgaaagtttg ttttatacaa acaacggagg acgctcattc aaagaatcag ttctgtcgat
     9781 tccggaaaac tatcagacag gggggataga tctttttcaa tcaccaaatg aagttactca
     9841 aataagcgcg aatacgttag agacaaaatt ttatttgttg aaaaaaggac caatcgatgc
     9901 agggaaaatg tttgcctgcc tcttccgttc aactgataac ggggaaacat ggcaattcgt
     9961 tcagcaacta tcgcaagtag aacaaggaga ttaaagaaga gagattgtga gcctgacgtt
    10021 cagcaccgag tcacaagaaa caaattcaaa aaacagcttc tcatatttgt tgaatagtgt
    10081 aactcgtgat tcggagttga caagagcaac aagaagcgat tttgaagtat agcttctcgt
    10141 attttacaag atcgtgtctt attgccgata ggttgtctct tgaacaccgt ttattcgtaa
    10201 aaagggattg tgacaagtct tttgtcacta cttaccgaac gaaactgaag gagctatcca
    10261 aaaagtatca ttagtattat tctttgtgtt tctagtggca ccactagtac atttaaaaaa
    10321 gctatcgatc atggactaat catacatgat cgatagcttt ttagataatg tttgttacgc
    10381 tatctgaaat tgactattat aaagactggc ataaagcgtt ggtgattgga gtagttcaga
    10441 atgtgttcct ttttcgacga tatcgccatt cttcattaca aggatcatgt ctgcattttc
    10501 aatcgttgac aaacggtgtg caatcacaaa acttgtccta tcttttgtca cagcttccat
    10561 tgcttgctga atcaatgctt ctgttcgtgt atctacgcta gaagttgctt catctaaaat
    10621 aacgacagga ggattcgcta gaatgactcg agcaattgtc aataattgtt gctgtccttg
    10681 agataacgtg ccgttttcgc tagaaatgat cgtatcatat ccgtctggca gtgttcgaat
    10741 aaagtgatca cattgtgcga tttcagccgc ttcgataatt tgttctcttg tggcatccat
    10801 tttcccgtag gcgatattat cagctaccgt tccttcaaac agccaggtat tttgtaaaac
    10861 catcccaaaa gaacgacgta gttctccacg tgaaagcttg gtaatatcaa gaccgtcgaa
    10921 ttcgatcttt cctttattca gttcataaaa acgcatcagc agattgacta aagtcgtttt
    10981 tcctgcacca gttggaccaa cgatcgctac cgtttgtttt ggctttactg aaaaatcgac
    11041 ttgattcatc aatattttat ctgatgtgta accaaactgt acatttttga aagctatttt
    11101 tcctttcggt tgttctaaaa gtcttgcatc tggaaggtct ggaatttcat ctgtttcatc
    11161 taatatctca aatatcctat cgattgctgc cattgcggat tggatcgagt tgatcacata
    11221 agaagcggta gaaattggtt cagaaatctg attgatgtac tgaagataag cttgtaagaa
    11281 gccgatcgtc acaccacctg atagaacaag catagcaccg aataccgcac ttatgatgaa
    11341 ggcgagttga ttaatgaaac gaatggccgg atagatagca cagttcataa attgagcacg
    11401 tttaaaagcg ttgtattgct ttttatttac ttcgtgtata gcagcttctg catgagcttg
    11461 ctgattgaat gttttgacca ctagattacc agctaagatt tcttccattc gattatttaa
    11521 aacacccagt tcatactgat tctgttcaga aatctgtttg tttttgttcg caatcttagt
    11581 tgtaacaatt gaactgccaa cgatcagcaa taagacgagc aaagtaagct tgctttcgat
    11641 ataaaacagc atcagaccag cagcagctat tgttacgaca gaagtaaaaa attgattgat
    11701 acctgtcaat aacacttgag aaagttgatt gagaccggta gttgtccgac taatgatgtc
    11761 acctacttga tgattgtcaa aaaacgacat cggtaatgtt ttgaattttt ttgtgatttc
    11821 ttttcgcacc ctcaatgtga tcttttcgct taacgctgcc attgtccgtt cctgaataaa
    11881 tgaagtgatg ctgcttaaga ctgaacagcc gatcagcaat aagacaggga acaacaatgc
    11941 ttgtttgata tcactgaaag aaagctgtcc aatacctgtt tttcttattt ctgataagag
    12001 atcatcgatc ccgattccca tgatcaaggg catggctacg actaataggt tcccgaataa
    12061 actgcataga aacaatccgt aaaaatattt atgttcaggt ttgatcattt tccaaaaacg
    12121 tatcaaagca cgcgtgttca acgttttttt cttttccatc gtatcccttc tttctatatt
    12181 ccttgtgatt ttgcaaactc ctgataagtt tggcaattag acagtagttc ttcatgagta
    12241 ccttgtccaa cgatttttcc ttcatctaaa acaatgatgt tatctgcttg ttggattgta
    12301 ctgaggcgtt gagcaacaat cacgagagtt ttctccgaca tgtgtttatg aagggctgct
    12361 cttaatgctg catctgtttt atagtctaaa gcggagaaac tatcatcgaa tacatagatc
    12421 tctgctggtt tgatcaacgc tcgagcaata catatccgct gtttctggcc ccctgaataa
    12481 ttagaaccgc cttgagcaac aaagctgtcc aatccgtcag gaagggtgtc cactagttct
    12541 tctaattgag cgatcttgat cgctttagac aactcttctg ttgaggcata ttcatttccc
    12601 atctgcaagt tgcttaaaat tgtcccgctg aataagaaag ccttctgagg gacataactg
    12661 atgtgggagc ggatctgttc ttgagtcatt tgagtaagag gaataccacc aagggttact
    12721 tttcctatcg tagggtcact aagtctcaag agaagtttcg ccaaactact ttttccagat
    12781 ccggtcccgc caacgatcgc tgttgttttt cctttaggta ttgtgaaatc aatatcttct
    12841 agaactggat cagagatttc agtatattta aatgtgacat gttcaaaagc agctgcattt
    12901 gtctgatcaa aggttggttc agctactgtt ttgatcgtct cttcctcaat ttcgatctct
    12961 gcttgcagta tttcttctat ccgtcgtaat gaggcaaacg atttagggat aatgaccaat
    13021 accatagctg cgatcatcaa gtaagcaagt gtcagcatag agtattcgac tacagcagtc
    13081 acgacaccga tttgtaatgc tccttctgct acaagatttc cgccaaacca caaaatagaa
    13141 gcataaacga ttcccatgag caaaaaagca attggagtga cccaagcaaa tattcggttc
    13201 actttgatca tttgattagc atagtcagca aagctcttat tcgttcgctt ttcttcatat
    13261 gattgattat caaaggcacg gatcatatta atcccagtaa agaattctct caatgtgatg
    13321 gtgatccgat ccatttttgg ctggatactc aaagataaag gtgcccctcg tttcatcagt
    13381 cgataaacaa tccatacata aaaaacaaca gagatcaatg taacccatgt tagtaataga
    13441 gaataacgaa acatcatgag aatggtgaaa acgcaaataa ccggtgctgg taagatcatt
    13501 tggcaaaata aaacaatcat ttgctggaca ttatcgacat cattcgtcat tcttgtcaaa
    13561 agagatccag aactaaaacg actgatatcc ttcattgaca gctgttggaa tttacggaaa
    13621 tatttctccc gcgtttggaa tccaaaccta gcggaagcca atgctgaaaa gtaactagag
    13681 gcaactgcag cgattgttcc tagaaacgct acaagcagca tttcaactcc aatttttttt
    13741 ataactgagg cttcgccact tgctatacct gtgtcgatca gctttgctac taattttggt
    13801 acacctaatg taccggcgat ttctaaacag atcatcacaa aggtaaggag agcgagtcct
    13861 ttgtttttct gtaagaatgt ttttaagata gacatattat tcctcctttt ttcctgatac
    13921 ttttcgattc tataccttca agtaacttga aggtcaatag aaaaaagaat aaactgaaaa
    13981 agaggtgaga aaaaatgaaa aaaatgtata cgattggcca agtatcggaa ctatttgatt
    14041 tgccaaaatc aacgatccgc tattgggatg aacaaggatt aatccgttca agtagacaag
    14101 aagagaatga ttatcgattg tttgatatcg atgatatttt tatgctttat gatatcgttt
    14161 tttatagaaa attagatata ccgatcaaac agatgaagaa tttatatgga aaaacattga
    14221 cggagttata tgagacactt gatgaaacag aaagaagaat ccataaagaa ctggtggtga
    14281 tgaaacaaaa acaaaaagag ataagggagc aaaaaaaaca gttgaaattg atgatcgata
    14341 caaacgagga agaatttcct gtagaagaga tcccttttga ctgtatgatc tcaacggagt
    14401 ttgaagatat tgtggaaatc aaaaaatttc tacctaacta ttcaagcttt gggatgatga
    14461 gtatgccagc ttccagttca cagacgatgt atggattttt tatcgaccct agtgaagtac
    14521 atttatttac tcaagacgtg atttgggaga aaaaagatac ggctgtttat cgtcgattct
    14581 tattgaaatc cgagatgaac catgcggaac gtaataatat tttagaaatc agagaaagaa
    14641 tgtatgaaaa aggatggaaa acaggagaag tgatcggcca gtatctattg acgaatacgg
    14701 atgaaaacaa tatcagaact gaatattatc atgcatggat agaaatgaaa aaataggaaa
    14761 tatgtgttta agataactcg aaaatgatgg ttgttttagt tataaagaaa aattttctgg
    14821 ttcgattacg ggtttaatgt gggggattat tagtcgtgga tagatagaat tttagttttt
    14881 tagaggaaat atgtctttaa aaatggaatg gttgcaattc ttagcgatat atacgatgta
    14941 attgtcctct taaaaaagta tggaaaaata attgtattgg gtgttatgta taattcatgg
    15001 tgaactgaga ctaatgagaa gaaaaattca tattgttatg agtgagattg tatcagatga
    15061 gaatgataaa ttaaataggt gcataaaagc attacactta aaatacattg ttgcttacat
    15121 tattacaata tgttaataag gcaaaaataa atagatggat tgaataaaca tattttttaa
    15181 tcaaatagtc cctactgtga ctttcctcag ctatcggtga tactaccgat agcatttttt
    15241 tgcttataaa ataattataa gtatttagag atttttcttc taacattctt caaacaagaa
    15301 aaatcacaaa ggttattgtt atttttatat attcttttta agaatgattg tttttttata
    15361 gaaattttaa aaaataaaac acgttattga tggatagtta gtttgttatt tggtaatatt
    15421 atagaagttg actggtagtg atttattttt cgtcgtttta taaaaatgtt attttttgga
    15481 aaaattcaca aatatgtaac gaatgttttt ctggaatttg ctgtgttaaa aagcagtatg
    15541 actaatataa atactattgt catttatgca attttttatg gatagtaatt ttagagggga
    15601 atcaatgaag gaagaataga agggaaaaat agttgcaaat acgccagtta gcaaaaatag
    15661 caatacatct tcaagcttta aaattcgaga gaatcatctt ggtagtggaa tcaactacaa
    15721 caaaaggatt aaaccaatta atagatagaa ttaccaatgg aaaaatagaa aaggtagtta
    15781 ttctatacaa aagttgttta attcgcttcg gttatgaact tagtgaaacc ctttgcaata
    15841 tatggtacag aatatagaaa ttattgacat tacagaaaat gatgaagatt taatacagat
    15901 tgtcactatt tgtagatacc ttttacaagg aaaccgagcc aataaagcta agaagatgat
    15961 taaggagttg atggaagacg atacaagtta agaaagtgaa actacgccca aataaagagc
    16021 aaaaagagta attggacgtg gaaaatgcaa gaaatgaacc atcgattcgg tggacagttt
    16081 attagtaatg acggtttgag aacatccatg acgagaatga aggaacatcc taaatgcgtt
    16141 tagttgaacc aagtgccaaa taatatggcc aaataagcga tcagttatcg atgaatccca
    16201 agtattctaa actatatatt cattttgatg ctaagcattg atatattttt ttgggattga
    16261 tgaaggttaa ccaatacagg gactcactga tgaaattcta gagtctgacc ttggtatcaa
    16321 cgatttagtg attgtttcta atggaaaagt ataaaagtat ataagtacat taacaaaata
    16381 actattaggg ttacgctcca gcttgtgcaa ggcactggca ggaggaatcg tgaaatcata
    16441 attatggtta agccacacgg acaactaaaa gtcatacaaa gctatcgaat caatcaacag
    16501 aagacaatcg gcaatcatta gctttgttta cagcttacat tgcaacgctt gagttgaacc
    16561 gaaaatacga gggaggtaac gcagccattt tgagttgggg aatcttttta gaaaattatc
    16621 gggtaccttg ttgtttagtc aaaattataa gggggagtaa tagtgaggaa caaatttcat
    16681 aaactgttaa gtatgtttct agttatgctt attgtgatca atcaatttgg gaacataacg
    16741 gttctagctg agtctttagc agaacagcca gagcgttcgc tgacgatcga agttgatcaa
    16801 gaggaggctg ctttgggtga gcagttccag ttgcgagtca gaggaacacc agacctgcta
    16861 aatgcattgg tcattgataa gagtgaggat ttgattgaag gggaagtgaa gcaactcaat
    16921 gattacgaac gtctgattac ttattcttcc cagcattcag gtaaatacga attgaccgca
    16981 agaagcggtg atattcaatc aaatacggtc tcaatagaaa tcagtgtacc agaagaaagc
    17041 acaagtgagt cttttaatgt accagaagaa agcacaagtg aatcttttaa tataccagaa
    17101 gaaagcttaa gtgaatcttt taatgaagcc agatcatctg agccatctat aacgcaggaa
    17161 tctcagattg aaagacaaga ggagctcttg aattatgaca tcggcatctc tgctgagcgc
    17221 cccactttgc cgagcaggca tacacaaacg ttaaagggat acattcaagg aggcgctggc
    17281 gatattcttg aagaatatgg ggagatggtc gtacgagttc ctagagcatc gattggctta
    17341 attgagttca ttagagtgga ggtcgctgat gattcacctt taaagccact ggcattttac
    17401 caagaaggca cagacgttgt ttttccattt acctttgatt atgaaggatt aaatgaagcc
    17461 gctcagtcgt atacattcag tatcacgttt gaagttgctt tctttcaatc aggcggtact
    17521 gagccaaata atgactttca agtgagtctt acttatgctg agcgagcagc aaacacggaa
    17581 ttttcaatta cgcctattcc ttcatcaaga cccatttttt cgaaattata ctatggctct
    17641 agagaaatcg acagccaagg aaatcttggg aatctgctga ttgacgggca agacgtgacc
    17701 aacagtaata aatttatttt gcaggtaaat tatgaaggat cacgaaaaga cggtgtagtg
    17761 gttaccgatg tactaccgca aggaacaact ttggcaccga atccgactac atggagttcc
    17821 actggaaata gagaacctat ttcaggtggg gttcggatcg cagaagtaac gaatccaggt
    17881 gaagcaaacg ttagaactca ttatgtttcc gaggaatttg tggacaaagt atcttttaat
    17941 aaggaaacga atacacttgt tgtggacttt ggtaatctag cagagggtca atcgtatttt
    18001 attgaatatg ctcttgaagt gaccgatgtc gacttgttca atgaaggaag acaagaggat
    18061 gggttttctc ggaatcgagc gagtatgacc tacaataatc aggtaatgag ccgagactac
    18121 cgcttgagaa tccctgaaag taatcttccg gcaatctctt taagaaaaag tgtggacaaa
    18181 aatgttatca atctcaatga aaatgaacta acgtatactc tgcatgtctc gatgttttct
    18241 ggaacaagaa atacgcttgt tattgaagat gttttggaag aaggcatgga atttgtgtca
    18301 tttctatcag atattccctc tttcattgat gccgaagtca ataatggaat agttcgtttc
    18361 agtgcgaata atacgattgg tggtccgaca agttttaccc tctcttttaa ggtcaatgta
    18421 gaggcgtatg cggtcggcga tcaaatttta aactttgcaa cgcttgtgaa tagtgacaat
    18481 cgattgaata cgagtactgt aagaacaagg aaaatcgatg ggcgtattaa agtaattaaa
    18541 actgatgaga atggccaaag gctggcagga gcaaaatttg aaattttatc aagcgattca
    18601 caagtgatac aagaaggtat aacggcagaa aacggagaat ttttaagtga accgcttcct
    18661 gtaggtagct atcaagtccg agaaacagaa gcaccggaag ggtatctttt agatgcgacg
    18721 gtacatgatg tttttataaa tgaatactcc atagaagaag tgacgttaac cattgaaaac
    18781 atccttgata cgggtggtgt tgaactaatt aaacatgctg aaggcagtgg tgaagtcctt
    18841 caaggagctg tttttgagtt acagaaccga gaaggagaaa cgctacaaac cggtttaact
    18901 acaggagaag a
//
LOCUS       DAYNVV010000051        18612 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.053, whole genome shotgun sequence.
ACCESSION   DAYNVV010000051 DAYNVV010000000
VERSION     DAYNVV010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18612
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.053"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(51..1598)
                     /locus_tag="ACGXWR_002053"
     CDS             complement(51..1598)
                     /locus_tag="ACGXWR_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HFK0803586.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="ACGXWR_002054"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="ACGXWR_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFK0803587.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2043..2237)
                     /locus_tag="ACGXWR_002055"
     CDS             complement(2043..2237)
                     /locus_tag="ACGXWR_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803588.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
     gene            complement(2481..2765)
                     /locus_tag="ACGXWR_002056"
     CDS             complement(2481..2765)
                     /locus_tag="ACGXWR_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803589.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(2783..3673)
                     /locus_tag="ACGXWR_002057"
     CDS             complement(2783..3673)
                     /locus_tag="ACGXWR_002057"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HFK0803590.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(3693..3911)
                     /locus_tag="ACGXWR_002058"
     CDS             complement(3693..3911)
                     /locus_tag="ACGXWR_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HFK0803591.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(3881..5581)
                     /locus_tag="ACGXWR_002059"
     CDS             complement(3881..5581)
                     /locus_tag="ACGXWR_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFK0803592.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            5848..6621
                     /locus_tag="ACGXWR_002060"
     CDS             5848..6621
                     /locus_tag="ACGXWR_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803593.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(6702..7271)
                     /gene="thiT"
                     /locus_tag="ACGXWR_002061"
     CDS             complement(6702..7271)
                     /gene="thiT"
                     /locus_tag="ACGXWR_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015234 - thiamine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HFK0803594.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(7337..7439)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(7445..8416)
                     /locus_tag="ACGXWR_002062"
     CDS             complement(7445..8416)
                     /locus_tag="ACGXWR_002062"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFK0803595.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(8510..9883)
                     /gene="glmU"
                     /locus_tag="ACGXWR_002063"
     CDS             complement(8510..9883)
                     /gene="glmU"
                     /locus_tag="ACGXWR_002063"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HFK0803596.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(10386..11204)
                     /gene="purR"
                     /locus_tag="ACGXWR_002064"
     CDS             complement(10386..11204)
                     /gene="purR"
                     /locus_tag="ACGXWR_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HFK0803597.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(11371..12195)
                     /locus_tag="ACGXWR_002065"
     CDS             complement(11371..12195)
                     /locus_tag="ACGXWR_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HFK0803598.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(12168..12848)
                     /locus_tag="ACGXWR_002066"
     CDS             complement(12168..12848)
                     /locus_tag="ACGXWR_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFK0803599.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(12871..13809)
                     /locus_tag="ACGXWR_002067"
     CDS             complement(12871..13809)
                     /locus_tag="ACGXWR_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFK0803600.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(14054..14905)
                     /gene="ispE"
                     /locus_tag="ACGXWR_002068"
     CDS             complement(14054..14905)
                     /gene="ispE"
                     /locus_tag="ACGXWR_002068"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HFK0803601.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(15059..17632)
                     /gene="mprF"
                     /locus_tag="ACGXWR_002069"
     CDS             complement(15059..17632)
                     /gene="mprF"
                     /locus_tag="ACGXWR_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFK0803602.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            17773..18579
                     /gene="proC"
                     /locus_tag="ACGXWR_002070"
     CDS             17773..18579
                     /gene="proC"
                     /locus_tag="ACGXWR_002070"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFK0803603.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
BASE COUNT         5420 a         3969 c         3207 g         6016 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagttctttc aaaatagctt gaagaatata attgttaata
     2101 ccgttataga tcaaaacttc agaaccattc tctcttttga tgcgcatcgc taacttggca
     2161 gccgcgggtt tacctttttc tggtgcactc ttttcgtttc ctaattggac aggaacaatc
     2221 tcatttaatt tatacataga aaacctccag acttcttgat agctcaagta tatcttgagg
     2281 tgcatttgtt agtaaggtac tgttctatgg ggcgcttact taataccgag aaaatggttt
     2341 ttgaacatca cttattcaaa ataaaaaaag attgtgacac gaattttgtc acaaccttta
     2401 aatgtattcc tagagcaaag aagctaagcg aagaaatcca attctgatta tttattgtat
     2461 ttctttgttc agcatccttg ctaaaagccc atattggaca aagtattcac tacacccatg
     2521 atctcatctt ttcgagaacg tgctttttct gtcggatctt ctacctcttc tgtgtcaatt
     2581 cgaacaataa atttccgatt catcgtcacg taagcaccgt cgttgatcaa aataaacagt
     2641 tcgttctcat tatagtctgc acaggcatct ttccatacgt caaagccgtt tttttcagaa
     2701 gggatatccc gtttaaccac agtttttcca cttaattcgt ggaacgttac gtcataatat
     2761 ttcattatct ctacctcttt cgtcattcaa tattttgtac ttgttctctg attttttcta
     2821 agatcgtctt agactggacg acttgatttt taatttcgat tgcatttgat ttggaaccga
     2881 tcgtgttgat ttcccgattc atttcttgga tcaggaaatc taattcccga cctacaggac
     2941 attgtgcttc gataagttca tctagttttt gtacatggat cgccagacga tccagttcct
     3001 cgtgaatatc tccgcgttcc aacaagatgg ctagctccgt caacaaccgt tgctcatcga
     3061 ctttcgctcc aagaaattcc tccagctttt tttgatacct tatttgaaat tccttttcat
     3121 agatttctac aaaactatcg agttttttta gtacttcttt gaattcttca gtattctttt
     3181 tcaacactaa agctaaagct tgaccttctt tttctcgact cgcctcaata gaatcaagtg
     3241 cgcttttcaa tgtatctaga gctaactgtg ccaattcttc catgctctct tccggttttt
     3301 cttctaccgt tacgaagttt tcgtccagcg cgaagcgttc cgccatccga ctaattgaca
     3361 cttgattttg actaccgtat cgttgttgaa ttccgtctgt caattgagtg ataagtgaat
     3421 caatcaattc ccagttgatg acgatctgtt tttcgttttt gccaatataa gctagattca
     3481 caaatacttc gattcgaccg cggcttaact gctgtttaat aagctgacga aaatcgtttt
     3541 caacaaagtt caggatttta ggacttcgta tttgaacatc tagaaaacgc tggttgacac
     3601 tttttatttc aatatctaac tgatacgctt ttgtttcgcg gatggctttg ccaaaaccag
     3661 tcatactttt cattcgacag ggtccttcct cattacatat tttctattgc tttttgcagt
     3721 tgttcaaact cttcgttcgt caatgtcagg cctttcccca ttttttcatg gtctggcgcc
     3781 caatctcgaa gatcgaattt tggcgggcga ccattccagc tgactaggtt cagttcttta
     3841 cgccacccct tgttgttttc tgacaatata gcgatttctt ctacgatttc atatgaaaat
     3901 tcttgtgcca tggttgttcc tccttgagat aatataaata taggatcagt aatgtgtcaa
     3961 ctggttgctt aagcaattca tgctgcaaac gatccttgcg ttttccttgt agcagataat
     4021 caaaataaac agttttcgtg cgctcatttt gtattttttg ctggtatttt cgataccttc
     4081 gccattcttc agtacttaat tgaccaattt gtgccaataa atcatccggc atacttttta
     4141 tatcttgttg gcagatcatt tgaatcatca tgtctacttg atagatttca ttgggcagta
     4201 aaaaatgttt ttttgctaaa agttctagca tcgccaatcc gcatgtctct ggtacgaccc
     4261 tgttcttata taaattacgc agtttttgcc aaaattttat gcttttgaaa aaagataatt
     4321 ctaactgaat ttcttttgtt aagtaagaca aaaatcctcg ccagtatgtt cttgcaggtt
     4381 taacagaatg aaatgtatac cagttcccat agtaatagcc taatcgtttt ttcatttcca
     4441 gatagcctaa ttgtaaattt aattggttcc tttggctatc aaaaagcaga aagctgccta
     4501 gtgtccacaa tgtttgacat ttccaatgga taaaaatgtc tggcatacga atttttttcg
     4561 ctgggcctgg cccttgcaca tctacgacaa atgcctctgt tgctcctttg ttaatcgcaa
     4621 tatcaatagg tattttgttg cgatacccac cgtctgcata tttatttttt ccgatctttc
     4681 gataagccat agcgggataa aatgaagcag aggcgagtat ccaatctggt atttcttctg
     4741 tttttgtctg ttggatatca gtcactactt ccgctagttc tggcagttta gtagacaccg
     4801 tatataaacg tattttggga ttatgtttga gtaaggacaa atccaaattg tctttgacca
     4861 tcttttccaa tggagcagaa gaaaccccgc cttcaattag tgctgttttc gtcatttggc
     4921 gtctttctcg atagaagcgt tcacgaaggt cttcaactgc agccatttct ggtaacgcaa
     4981 gcacttgtct tgtcgacagc tttttccata aattcacagc ttttttcata tctccttgta
     5041 aaatcaatgc gccgttcaac gcacctaccg aggtacctgt gataatctca aagttgatat
     5101 catgttcctt cagcgcctgc cacacaccaa tctgataagc accgtgcgct cctcctccac
     5161 ctaaaacaag tgctgtatga tagaccagct ttttatttaa ttgtgtggtt ccttgatagc
     5221 cgtttttatg aaaaatacgc aaccattctt ctgatagagg agattgaaat aaaaaacaac
     5281 agttttcttt aataaaaaaa cgagcgcaag cttccatata ccgaaaaaat tttttccatt
     5341 caaaagtttc accttcaatc aacagattat taaaaataac atctcctcta cttttagcaa
     5401 tagtaaaata gacggtatat tttttcgata ctgctttaaa agcacattgc ttttttgcag
     5461 aacgccaaaa agcgtctcta ctttcttgat gactttgaaa aaatggaagg ggttgttttg
     5521 cttgctggat aggcgaatac agcgacattt tctgtgaaaa gtaaactttt tttatctcca
     5581 tcgcgctctc ctttttcttc aagtatacca gtacgtcata aaaaggtcat gagtctcgta
     5641 ttcgactttg tagattccat aagaaaacaa ttcataaaac ctcctttaaa taaaaaaata
     5701 caaaaatcac aaaaattaat tgaaaatgag agtgttttca atgaaaacgt gattttgtaa
     5761 tggaatttta aaataaaaga aacaagcttt tttaatgcaa atgttgtaaa ataaaagaga
     5821 ttaagaggaa ataagaggag gaacatgatg actgagtcag tttatgtaca tattgatacc
     5881 acaagtaatg ctgttttaac aaaagggctg actgctactg actttgcaaa cagtatcgtg
     5941 cattttcctc aaaacttgct cttgcttgat ccatctgctt ctgctggaga atatgaatcc
     6001 catacagggc tgaaagtaat ccgtggtaca gaaaatattc agcgtttctt ttcctcttct
     6061 cgtaacaggc gtggattcga tgaattgaag tggatcgact ttactgattt aacgatgctg
     6121 aaagaattga cacctttaga aatttcagaa ttattatatt ttggtcatat gaaaacacat
     6181 cttcattcgc cgttttttta taaactacag aataattttg tatacttcga tcttaatgat
     6241 cagctgaatc ggatttatta tcgctattta gatgaatttt ataggatttt tgctagtaaa
     6301 ttaagttcga tcttgtcaga taagatcaat gtaaaaaaat cttttttcaa aaaagaaaca
     6361 cctgttgaaa aaatcagtgt ggaattattg aaagaaatgc gtaatttgat gcaggaaggg
     6421 atcatttttt cttttgatca agttggtttg atcgatggta aatatcgtat cccaatctat
     6481 gtgattgaag attatatttg gaaattaaaa ggcacccggt atcgagaaga ggaaatcatc
     6541 gctactttaa tctactctgt caccgatcga cactggcaat tggtagaaga tgccgatctt
     6601 tcttatctgc cattgaagta gatctatttc ttatcaaaaa ataaaaagga aacaagaaac
     6661 taggacatga ttctgtctca agtttcttgc ttctttttta tttacagctc ctgtcgttta
     6721 tctggcacaa aaatcgaagg agtcgtttgt tggatcccta ataaaacgat gatcgttaca
     6781 atagctgtac tcaacccgct ggcaccattc attacgaaag aaaagagcca aggattcatc
     6841 ccccatagtg catacgctcc ccagaaaacc actcctgcaa taaaatgcca aaaatatctg
     6901 gaaagtgcgc caatcaatgc accaaacacg atgctttttc taatttgttt cgtattatcg
     6961 tctacatagc ctttttggac atttgaagcc atgagccctg ctgcgcctgc aaaagtatag
     7021 gcaatcgggt actcaatcaa cacttgaacg acacttaaat aataaacttg tcccaacgga
     7081 aaatgtagga tgccccaaat gaaacctgcc agcatccctg cctttgtccc tcttcttaac
     7141 gcaaaaagag tcaatggaat ctgccctaat gaaatagaaa aactgctgcc gatctggatc
     7201 ggaatcaacg acaacaccat cgctaacgct gcaacaatcg ttccttctac ccaaactcta
     7261 ttttttccca taaaaaaact tcctcctttg aataaaaaag tcacaaagga ggaagcagct
     7321 ttcgaaaata gtcaaacagc tgtttattca caattcctac gctcgcataa ccgatacagg
     7381 tacgaagggt ttagaaatag attcaatctc agcccaattg gactcccctt tgtgagttta
     7441 tttattattt attttttgtt tcaaacaatg gactaactgg tttgttttca tggatacgtt
     7501 tgattgcatc tcccattagt ccgccaacac ttacttcatc gattttgtcg attttacgat
     7561 cttctggaag atagatcgag tctgtaacaa ctagacgctc gatagctgaa tcttctattc
     7621 tttgtaaagc agggccggat aatactggat gtgtacatga agcatacaca ctagttgcac
     7681 cagcttcttt caaagcattg gcagccaatg tgatcgtacc tgctgtatcg atcatatcat
     7741 cgatcagtac acaagttttg cctttgactt gtccaatgat attcattact tctgcaacat
     7801 ttgcttttgg acggcgtttg tctatgatcg caatcggaga tttcaaaaat tccgctaatt
     7861 tacgtgcccg tgtgacacca ccatggtctg gtgaaacaac gacaacatca tcgcctttga
     7921 ttcctttttc taagaaataa ttggcaataa gtggcgcacc catcaaatga tcgactggaa
     7981 tatcaaagaa accttggatt tgaactgcat gaaggtccaa agtcagcatt cttgttgcac
     8041 cagctttttg aatcatgttt gctactaatt tcgctgtgat tggttcccgt gcacgtgctt
     8101 tacggtcttg acgcgcatag ccataataag gcatgactac gttgattgtt tttgcacttg
     8161 ctcgtttcag tgcgtcaatc atgatcagca actccatcaa gttatcattg actgggctgc
     8221 tcgttgattg aataacatag acatgcgatc cacgaatact ttcttcaatg tttacttgaa
     8281 tttctccatc actaaattga gtaacagatg attttcctaa ctcgacgccg actgctgctg
     8341 caattttctc tgctaatggg cgattggaat ttaacgcaaa aatttttaat cttgggtcaa
     8401 agtaatgttt tgacatgggg acctccactt tctttttcac aactctagaa ttctacctaa
     8461 taaatagtag tcatattttt taaataaatc aagtgatttt gcaaaagtct tagtttagat
     8521 aagggagttt ttttgcatat ccttctttat tgacttgtct tgctctcgca attgccagcg
     8581 catattctgg aatattgtct gtaattgttg acccggcagc aatcgaactg tttttagcta
     8641 cctcgacagg tccgatgata ttcgtgctag aaccaataaa gctgtggtcg ccgacagtcg
     8701 tatgatgttt gttctttcca tcatagttga cgaagacaac accacatccg acattgattt
     8761 cttctcccag cgtagcatca ccaacataag tcaagtgacc gactttagtt cctttgccga
     8821 tttgagcatt tttcacttcc acaaagtttc cgatatggac gttttcgcca atttcagctt
     8881 ttggtcgtaa atgtgcataa ggtcccacat ctgcatgttt cttgacatgg ctgctttcaa
     8941 tgactgagtt ttcaatgacg acgtgatcct caatcctact gtctacgatt tttgaatgtg
     9001 acccgatgac acaatcagaa ccaatgactg tatttccttg gatttgtaca cctgcttcga
     9061 tcaatgtgtc tggaccgatt tctacgcctg catcgatgta tgtcgttgct gaatcgacaa
     9121 agcttacgcc attgaccata tgcatctggt taattcgctt tctcatgatc tcatttgctt
     9181 tagctaacgc gatccgatca ttgactccca ttgattcttc aaaatcatcc gtttgataag
     9241 cagcaactgt atggccttct tcttttaaga tttcgatgat atctgttaga tagtattcac
     9301 cttgagcatt gtttgttcca actttgctta acgcatcgaa caaagcttcg ttgtcaaaac
     9361 agtaagttcc tgtattgatt tcttgtacaa gagcttcttc tggtgttgca tctttttgtt
     9421 ccacgatttt ttctacgatc ccaatatggt cacggatgat tcgtccatat cctgttgggt
     9481 tttctgcttg tgccgtcaag atcgttgcac ttgcattttt tccttggtga tattcaaaaa
     9541 gattgttcag cgtttcagta gtcaataatg gtgtatcgcc actgataact aacgttgttc
     9601 ctttttttcc ttccaagaaa gaagcagctt gcaaaacagc atgtcctgtt cccaattgtt
     9661 ctgcttgtaa cgcatattta ctgcgttctc ctagttgtgc tttaacttgt tctgctccgt
     9721 gtccaacgat cgtaatcact tcatctggtt tcgtttcact gacccgatta atgatatgtt
     9781 ctaccatagg tttaccagaa acgggatgta aaactttata taattttgac ttcatgcggg
     9841 tacctttccc tgccgccaaa ataattgcat aacgtgcgtc caactgcgtc actcctaaat
     9901 atagtttgct gatttcagtt tatcccagta tacccatttt ttcaacaaaa caagtgattt
     9961 tcttttatcc cagcgttttc tggataaaaa aatagataga ccataacggg cctatctatt
    10021 tggtaaccgg tgctctcctg ccaactcctc ggtcacaagt cacactactc ataaaacatg
    10081 aaaagctgtt ttttgaaatc gtttcttgtg acttagagtt aaacggtagg cttacaacct
    10141 cttcattaaa cgtttttcaa tcagctgacc ttcggtatta gctcaataaa cggcaaaata
    10201 tgaggagcaa tttttccgtt tattgagcta atactcagga caggacgctg atttcacaac
    10261 ctctagataa acggtgttca aaagccagtt tctcggtatt aagccaaatt tatgaaaaaa
    10321 tgtggaaagc cattttcaca aaatttttct tactactcga aactaagcag ctttttcaca
    10381 acctcttatt ctgaaaaata atttcctggc acaaccgtaa tatttttcgt ttgagtatct
    10441 acatctttga cataaagcag tgacgtataa tcatcgatgg cgcgatgacc gttgaatttt
    10501 gattcggcaa atacagtgat gccaacaagt tctgattcga attcttcaat caagctcttc
    10561 attccgttga ctgttccgcc gcctttcatg aaatcatcca ctacaaggac acgtgaacca
    10621 cgtttcaaac ttctcttaga cagttccatc ttttcaattc tttcagaaga tccagacaca
    10681 tagttgacac ttactgttga tccttctgtt atttttgagt cccggcgtac aataacgaat
    10741 ggcgcattca gataatagga cacagcttgg gcaataggta cgccttttgt ggctacagtc
    10801 attacagcat cgattttttc accaaggtat ttagaagcaa tgattcttcc aacttgacgc
    10861 agcagttcag gttctcctaa caaatcagag agataaacat atcctcctgg aagcagacgg
    10921 tcttgttctg atagacgttc tgctagagat tcaatatatt ttttcgcctc ttcatatgaa
    10981 atttcaggga tgaacaatac accacctgca gcacccggga ttgtttccaa ggttccatac
    11041 cctcgttctt taaatgtttt cttgatgatt cccaaatctt cactgataga agatttagca
    11101 gattcataac gttcggcaaa gcttgttaag gaaatcaatt catgcgggtg attcaataaa
    11161 tactgtgtca tgtcaactag acgttcactg cgacgtactt tcacctattc caactccttt
    11221 taagaaattt tatcgtttta cattatataa gtttttcttc aaaaattcga gcattttatg
    11281 aaaaaataag aaaatagttc ggtatttatt aaaataaaaa gaagcctata aaaaattttt
    11341 cgtttttata aggcttcttt tctttataat ttagttattt tttcttctga aggcaaccaa
    11401 tattcgtttg atgatattta caatcaggaa caaagcaata aagactaatg tgattgttgc
    11461 tcctggaggt gtatctagat aaaacgagct agttagtcct gacagcatcc ctagaaatcc
    11521 tacacaaaca ctgatagcaa tcacgacatt gaagcttttg cctaatcgca taccgattgc
    11581 tgcgggaaga accatgattg cggatatcaa aagtgcaccg gcaatcggga tcatcacagc
    11641 aatagccaca ccagtaatca cattgaacat catcgacatc aaatgaacgg gtagcccatc
    11701 cacgtgggcg gtatcttcat caaaagtcag aacatacatc ggccgtttga ataaaaagaa
    11761 caatataccg atggcaacga ataagattcc taaaaagatg acttgctccc atgtaatggt
    11821 cacgatcgaa ccaaacagat aggattggat acttgttgct gaattccctc cgctcaaatt
    11881 catcaatact aacgctagcg ccaaaccacc agccattaaa atggcaatgg agatttctga
    11941 ataggttcgg tagatcgttc gcagatactc caatatcaca gctgctaata caacgactag
    12001 catggtcgta agtgtaggat taaggttcaa aaagaatcct aacgctaccc ctgctaaaga
    12061 gacatgagaa agcgtatcag ccatcagcga ttgtcttctg atcactaaaa acacacctag
    12121 catcggggcg attccggcaa tgaagatagc ggcaagaaac gctcttctca tgaattcata
    12181 tgaaagcaac gccattgaga atcctccttt ctcaccagtc ggatctgtct gtccgcatac
    12241 tgtttgatat cttcatgatc atgggtgatc attagaactg atttcccatg gacatgcgca
    12301 ctatgtcgga gaagacgata aaattcattt ctggattctt catccatacc tgttgttggt
    12361 tcatcaagaa caaataagtc agggtcagta gcaaaaatac gcgctaaact gattcgctgc
    12421 ttttgtccgc cagacaattc acctattcgc cgatttcgca tatcccacat ccctacagct
    12481 tctaaagcac gctgtacatg ttgatgatct ttttcagaga gacgcttgaa ccagcggcct
    12541 cttggatatc ttcctgaacg gactaattcg atcaccgtac taggaaaacc tgcattgaaa
    12601 gatgcaactt gttgaggaat ataaccgata cttaattttt ttccttcttg atttttctca
    12661 gcaatcttta tcattccttt tgaaggtttc agtaatccta acgatgcttt caccaaggtt
    12721 gacttggctg ctccattttc tccagttaaa atgacaaatt cacccgcatc tacatgataa
    12781 gagacatctt ctagtacagg ttcatcatca tagtaaaagg tcaaatcaga tatttcgata
    12841 taacgcacct tacaacctcc attctaaaac ttaattgata ctttctttta aagctttcag
    12901 atttttttcc atgacagaaa tataattttc gcctgctttg atttgttcat tagtcaagct
    12961 ttctaaagga ttcaacactt ctagcttcac tcctgtttca ttcgacaatg tctcagctac
    13021 cttcgaagag gcattttctt caaaataaat cactttgatg ttgtttttct tcacaaattc
    13081 ttttagctca gctaagcgac ttggtgtggg ttcctgatct ggtgaaacgc ccgaaatcgc
    13141 tacttgtttt aagtcgtatt gattcgctaa ataagcaaaa gcagcatgct gagtgacaaa
    13201 tgtgcggttt gttgcatctt ttagctcatc ggagtatttt tgatccagtg cttcaagctt
    13261 tttgatataa gcatcggcat tcttcgtaaa agtttccttt ttatctggat atttttcgcc
    13321 taattcttca gcaatcgttc tgacttcttt tatagctaat accggatcga gccaaacatg
    13381 tggatcgtat tcatgtgaat gaccatgccc ttcttctgat tcttcatgtt cgtctgcttc
    13441 ttgcgattct aaacggtcga ttcctttagc tgcttcgatc atcaaggtct gtttgctatc
    13501 cactgaatcc tttaacgaat ccacaaaaaa ttccatgtct gaactattat acacgaaaac
    13561 atctgcatcg gaaatttctg ctctttcttt tgcacttggt tcgaaatcat gcggctccgt
    13621 tccagcaggg atcaaaagtt tcacgtttcc ttcatcccct acgatctctt ttgtaaaatc
    13681 atacatcgga taaaaagtcg taacgatcgt caaatcctct tttttgtctg cttccttgtt
    13741 cgtatttcca catgctgcaa acagtaaagc acctatcatt accgtagctg tcaaaagata
    13801 ttttttcatt tatatgctcc tttcaatgaa caaatcggaa ttttacgatt tattaacgtg
    13861 aactaatgta tcaaaataaa aaaacacagt caatagaaat ccatcaattt ctgatttaag
    13921 catgtatatt cttgattaaa tcgtaaaatg gatgagttgc tgctcatatc tagccatttc
    13981 actacaataa aaaactgaag aataccattt taggattcct cagtttttca tcacctattt
    14041 tacttcttat attttattgc agggttcgta ctaaataaac ttcctcacaa aaacctttta
    14101 acccattata tactctctgc gctcttgaat aatgttgaca caaggcaaaa acggttggtc
    14161 cgcttccact catcaatgca gcatctgctc cgtacttgat catacgctct ttgatttgat
    14221 ggatgactgg atgccgcttt cccgttatat cttctaaact gtttcccatt tttttgatca
    14281 tctgctgata atcttgctct cggatggctt cagcaagtcc gtggatgtct tgatgttgga
    14341 tggcttgcgt atctacttct ctaaacactg tacgtgtaga gacactcatt cttggtttga
    14401 ccaacacaac ccagcactgt ggcatagaag gtaatacttg gatttcttcc cctttgccac
    14461 cgacaaatgc cgtacttccg tagacacagt aaggaacatc tgtaccgact tccaaaccga
    14521 tttctgccag ttcttctaac gaacagccca gattccataa ttggttgatc cctcttagag
    14581 cagctgcaca gtctgtactt cctccgccta atccagctgc tactggaata ttcttcttaa
    14641 caaagatctt gacaccggtt ttgatattgt atttattttt tagcaataaa gcagcttgat
    14701 aaacattgtt ccgttcatct accggtaaaa atgctttatt tgtttctaca atgattttgt
    14761 cttctgttat ttcttcaaaa aatagatgat ctgccaagtc tacgctcgac atcaccattt
    14821 ccaactcatg atacccatct tgccgtctat ataatacatc cagtcctaaa tttatcttgg
    14881 ctggcgcttt ttcaatcaat tccatcctct cacccattcg aaaagtctaa gtcgcaagta
    14941 ttctatcata gggaaaaata aaagtatagc ttatgtctgc ctagtggttg attttgtcat
    15001 cgtttcaaca gctttcacag aattttctct tcataatcca aacaagttct agtgattctt
    15061 ataattctgt gagcacttct tctgccaaac tcggaacatt tcctttttct tttcctatca
    15121 gactgagtag ctgcatggta gcaaatccga aattacttcc tttcctataa gcaaaataac
    15181 gtccttccca atgatcgaca tattttaatt tcttttcata agcagactgg aaggaataga
    15241 aaaaattacc ataattatat acgatatgca tgactttttc ttgaaagaaa gaaaaatctg
    15301 tttctccaac attagctaat ggagctaagc ctagattggc ttccgagtag cccattttct
    15361 cgtatacaat aaacagattg gctaacagat agtcagctaa ttcctcagat tctttaggta
    15421 agacccgcaa caaatcatat cccgcctgct tcttcgtcat cggctgagcg gtgatgaagc
    15481 caacgacttt ttgatcttta cggacaatac cgacaccgct agataataca tatgatttat
    15541 caaatcgtcc cacagagaag tatttttctc gtgcaccttg aagccatttt tgtgaaactt
    15601 catttacagc ttgatgtaat tcttccggca gttgatcgta ccaagtaaaa tggtatcctt
    15661 ctttcatcaa acgttgatat tcaagttgct gactcagccg agacaagtct tctgttgcta
    15721 gatcaacaat ccctgcttca cctactttcg tgaagtgaaa acccaattca tgaagcatca
    15781 ctacgtagct ttctgatatc ttataaaacg caagctgata gcctaaacaa tctgcttgtt
    15841 tcataaactg attcgttgct gcccgcatca ttttaggatt gccaactgga tctcctaaaa
    15901 caaagcattt gtttcctttg atctgataac caaaaacgac ttgatcttgg tcgtcttctt
    15961 ggtaataaaa ataactgtaa cctgacaagc gaagctgatg gcttgtagct gtgcctccgt
    16021 atgtttccaa taaacggtca aaacggtctt tttcgtactc actgccaagc ttcgtagtat
    16081 cttcagctaa atattgataa agcgccacta aagctagcaa tgagatgccc aaaccaataa
    16141 gccctgagaa ccacacatca tctgaaggaa acaaaataaa atgatttcct gttattcgac
    16201 cgactaaaaa gcgtccgctg tgatagcctg caattgcgta aacgataaac aaaaagccga
    16261 acaagctagc atcaaagatt atagctcccc aagaataaac gaattttgtt cgataaaatt
    16321 cttttctgga taaccacaca gctaacagaa tcaagacata taccaatatc aactgccaag
    16381 ataacgtacg tgtgattgta tttaaaatac caaaagatag taaagcaatc gtaggcagaa
    16441 atgccttttt gacttttact gaaagtgctc tagcaaggcc gagtaataaa aagccaacca
    16501 atagattcac tgtctgatct aaaaaattga atgagaacgg caataatact tgaaatagcc
    16561 gactgattgc agacagatta gtgattgttg atagaagtac catcatgatc cccgcaaaat
    16621 agacagcact tacgagcacg atatgcgcaa ccttttggaa aaacagtcgc ggaatgttat
    16681 ctaaaaatcg attgattttg actcctgtat gtgtgatgaa caatagaagt cccgtcataa
    16741 aaggtagaac ataataaaac aaccgataat ataatagcca aactactgct acatcttgcc
    16801 gaacaggcaa ttgactcatt cctaagatca tcaaaacgtc aaaagtcccc attccacctg
    16861 ggaccatcgt cagcattcct atcaatgtag caatcatgaa cataggatag atcgaaagca
    16921 tcgaaatatc tattctcatc aacttgccga tgatcaaaaa taccgcaagg gctcccgtcc
    16981 attgtccaaa ggatgccagt agcagaccaa gcaagccttt tggataaaac tcgaagaaca
    17041 atgtctttct ctttagataa gcaaaaaaga aaatgactgg tgctaaaaaa ctaccgccga
    17101 aaagccagat ccaatagctt cgaaaaatac tttctgactg aataaaaaag acatcaataa
    17161 atgtaagaaa cgaccataca gacaaaccag tcagcataaa tagtgcgact tttgatacag
    17221 tggctaaaac catttttcta tttgtctgct ttccataaaa actagcccgc agacttgctc
    17281 ctaccacacc accaaaaccg gcgagattgt tgatcgtgtt tgttacccac gcagcaagaa
    17341 gaaactcttt tctttccatt tttggttttc cttgtttttc taagactctg atcgtcaccc
    17401 aatcatacaa caacatcgga gtgacaccca gcagtccagc cagaatcatg agcaggatcg
    17461 tcatgcggct ttgttgtccc atcctttgcc aaatatcttg ccaactcatg ccattagcaa
    17521 tatttgcgac ttgatttgcc acaaagacta acacggagcc gaaaaaaatc agttttaaaa
    17581 tcagactatg ttcctttatc cattgcagca tcaagtatcg tttatttttc acattttccc
    17641 attcctaact tgtatacttt tgtgtcatac cccaatgtta tcttatttat tttaattttt
    17701 ccactttaga cctgttcttt gcttgcgatg atagaaaaag aaagatatcc taatgctaaa
    17761 ggagaggata acatgaaagt aggatttatc ggcacaggga atatggcaca agctattatt
    17821 gatggtttat taaaaaaagg aacagtctcg aaagaagagg tgttcgtttc cagtggacat
    17881 tttgaaaatg cacaaaaatt tgctgctgaa actggcgtcc atgcatgcaa aagtaatcag
    17941 gaagttgcat cacaatcaga tatcgttctt ttagccgtga aaccaaaaat cattgaaaaa
    18001 gtattggaag aactaagaga atatagccag aaagtcttat tcatttctat tgcttcagga
    18061 aaatcattaa cagatttaga aacagcgctt gaagatcctc aggcctccat cgtacgtgtg
    18121 atgccgaatg tcaatgtcag cgtaggagca ggcgtttctg cgatttgcaa aaatgaagct
    18181 gccacggagg aacagcttca gcaagctacg atgatttttg aagcaatcgg cagcgtctat
    18241 cctttagcag aatcagattt cagtacattc attggccttg ctggcagctc acccgcattc
    18301 gtttacatgc tgatcgatgc gatgggacgg actggtgtac tgaatggttt gtccaaacag
    18361 acagccactg agattgctgc aaaagcaatt atgggttctt gtcaaaaatt cctttcaagt
    18421 gataaaaatc catgggaact tgtagaccaa gtttcttctc ctggcggtac aactgttgca
    18481 ggtgtagttg ccttagaaga agcaggattc atcccagcaa tcatcaaagg aatcaatacg
    18541 acgatcgaga aagatcttga gatgttgaat aaaaaataat gatagcaatg ttttttcgtg
    18601 ccttacaaaa aa
//
LOCUS       DAYNVV010000052        17537 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.054, whole genome shotgun sequence.
ACCESSION   DAYNVV010000052 DAYNVV010000000
VERSION     DAYNVV010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.054"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(36..845)
                     /locus_tag="ACGXWR_002071"
     CDS             complement(36..845)
                     /locus_tag="ACGXWR_002071"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFK0803604.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            1138..2574
                     /locus_tag="ACGXWR_002072"
     CDS             1138..2574
                     /locus_tag="ACGXWR_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFK0803605.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            2744..3940
                     /locus_tag="ACGXWR_002073"
     CDS             2744..3940
                     /locus_tag="ACGXWR_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFK0803606.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(4002..4187)
                     /locus_tag="ACGXWR_002074"
     CDS             complement(4002..4187)
                     /locus_tag="ACGXWR_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HFK0803607.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            4418..7732
                     /gene="dnaE"
                     /locus_tag="ACGXWR_002075"
     CDS             4418..7732
                     /gene="dnaE"
                     /locus_tag="ACGXWR_002075"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HFK0803608.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KRQLIYLLGEDNVVFK"
     gene            7900..8862
                     /gene="pfkA"
                     /locus_tag="ACGXWR_002076"
     CDS             7900..8862
                     /gene="pfkA"
                     /locus_tag="ACGXWR_002076"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HFK0803609.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            8936..10720
                     /gene="pyk"
                     /locus_tag="ACGXWR_002077"
     CDS             8936..10720
                     /gene="pyk"
                     /locus_tag="ACGXWR_002077"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HFK0803610.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(10755..11657)
                     /locus_tag="ACGXWR_002078"
     CDS             complement(10755..11657)
                     /locus_tag="ACGXWR_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFK0803611.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            11843..12412
                     /locus_tag="ACGXWR_002079"
     CDS             11843..12412
                     /locus_tag="ACGXWR_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HFK0803612.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            12470..12649
                     /gene="rpmF"
                     /locus_tag="ACGXWR_002080"
     CDS             12470..12649
                     /gene="rpmF"
                     /locus_tag="ACGXWR_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFK0803613.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            12819..14240
                     /gene="gndA"
                     /locus_tag="ACGXWR_002081"
     CDS             12819..14240
                     /gene="gndA"
                     /locus_tag="ACGXWR_002081"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HFK0803614.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDEAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            14433..15119
                     /locus_tag="ACGXWR_002082"
     CDS             14433..15119
                     /locus_tag="ACGXWR_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFK0803615.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            15116..16621
                     /locus_tag="ACGXWR_002083"
     CDS             15116..16621
                     /locus_tag="ACGXWR_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFK0803616.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            17308..>17537
                     /locus_tag="ACGXWR_002084"
     rRNA            17308..>17537
                     /locus_tag="ACGXWR_002084"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT         5674 a         3057 c         3679 g         5127 t
ORIGIN      
        1 gtcacaacct cttttttgtg gaatctaatt ctctattata gtttaagtag tttttccaga
       61 taaacagcta aaccgtcttc ctgattgctc aaaggagtga catcatttgc aatgcctttg
      121 agttggtcag taccgttagc catagctact ccccaacctg cataatccaa caattccaaa
      181 tcattatgct cgtcaccaaa ggcaatgacg tctttttgat cgatagacag gtagttagca
      241 atctcttgca cgccttttgc tttttggatt ccttttgaaa caatctctaa gatggcagta
      301 ggtccacccc atgtccgaac atcgacataa ctgccaaatt gacgtgttaa ttcagcagat
      361 acagctcctg caaaacgttt gtctgttcgg acaagcaaag atgtaggatt tgtcgtcaaa
      421 tttttaggag aaagcaaatt cttctctcct ggacgagaag aagcaaaaat tttttcatca
      481 aagaaatcaa aactgtcaat aaaaaaagta tcacgatttt cagcagcgat aaaatctaaa
      541 tttagctgct ttttttgcga taagatttca aaagcgattt cacgattgat caacgtttct
      601 ctttcaccat cccagtgctg attagggatg tgtactaatg cgccgttaaa attaaccatc
      661 ggtgttgtta attctaattg ttggtaaaac tgatggctca ttcggaatgg gcgtcctgta
      721 gcaatactga catgatgacc ggcattgatt gcttttttta gagtctcttt tgttttagat
      781 gtaatcatcg aatcttgatt gagggtagtt ccgtccagat cgatggcaat taatttttta
      841 ttcaataagg gtccttcctt cctcaactag catttgtttt agtctagcat attttaggta
      901 attaacaaga gcaatcagct attcctaaca aaaactacag ttatggctat ataaatagct
      961 aaacataagc taaacacgaa cgttaagtat tattttcgct ttttttgtta aaaaaacgtt
     1021 gaaaagcgaa tgaaacgtct atataatttg aaattgttcg atggatttgc cctattttac
     1081 ttatttttta ttattatagt tttccatcag aaaaaaattc agggagtgga actttttatg
     1141 gaaaagtttt tcggtttaaa gaaaaacaat acaaatgtat caactgaaat aatggcggga
     1201 gtaacgacat tctttgccat gagttatatc ttattcgtaa atccgacgat tttgtcagca
     1261 tcaggtatgc ccttccaagc agtatttcta gcgacaatca ttgcatcgat tattggtacg
     1321 ctggtaatgg gattgttcgc aaatgtacca tatgctcagg cacctggtat gggattgaac
     1381 gcatttttca cttttacggt cgtttttggg cttggttatt cttggcaaca agccttggca
     1441 atggtgttta tttgcggatt aatcaatatt tttattactg tcacaaatat tcgaaaaatg
     1501 attattcggg cgattcccga aagtcttcaa catgcgattg gtggcgggat cggtattttc
     1561 gttgcgtatg tcggaatcaa aaatgcagga ttcttatctt tttcagcaga ccagtcagct
     1621 atttcgagct ctgtcgttga aggcggaaaa gcgacaaatg ttacgataaa tggtggaatc
     1681 gtccctgcgt tagccaactt tgacaacgct cctatcttat tggctgtgat tggtttggta
     1741 ctgacagcca ttttagttgt aaaaaatgtc cgtggggcta ttcttatcgg tatcgtagcg
     1801 accacagtcc ttggtatttt tatgggtgtt gttgatttaa gttccattga ttggcaaacg
     1861 aattcgttag gtaattcatt taaagaatta ggaacaactt tcggtgcagc atttggttct
     1921 gaaggcatgc aatctttatt cagtgattct tccaagattc ctcaagtatt gatgacgatc
     1981 atcgcattca gtttatctga tactttcgat acgatcggaa catttatcgg tacaggacgc
     2041 cgcacaggta ttttctcaaa agaagacgag atcgcgttgg aagatggtcg tgggttcaaa
     2101 acaaaaatgg ataaagcact atttgccgat gcgatcgcta cttctgtggg ggctatcttt
     2161 ggtacatcga atacaacaac ttatgtcgaa tctgcagctg ggatcggggc cggtggacgt
     2221 actggtttga cttcagtagt agtggcagtg ctattcgcat taagtagttt attctctcca
     2281 ctgatcgcca ttgtaccaaa tcaagcaact gcgccagcat tgattttagt tggagtaatg
     2341 atgatggctt cttttgcaga catcaaatgg ctagatatgg aagaagcttt accggccttc
     2401 tttgcatcga tctttatggg attgtgctat agcatttcct atgggattgc agcaggattt
     2461 attttctata caattgtgaa agtaatcaaa ggaaaataca atcaagtttc tgttgctttg
     2521 tggatcgttg atattttatt cattatcaac ttcatcattc tagcaacaat ttaactaaag
     2581 agaagggatt ggaacagtat ttgttctgat ctctttttgt tttacataaa aagaacgtta
     2641 catataaaat gacctttgcg ggatttttct ctttttactg gcgagatcgt tgcttgttta
     2701 ttcgaaaata ggtatgataa aagagacgaa agagggatga tagatggaga ttaattggag
     2761 aaaaaattta gtgattgcgt ggattggctg ttttttcact ggtgcaagta ttagtttagt
     2821 tatgccattc ataccagttt atgttgagca actaggaaca ccaaaagatc aaatcgaatt
     2881 gttttcggga ctagcaatct ctgtgactgc ttttgcatct gccgtggttg caccaatctg
     2941 gggaaatcta gctgatcgaa aaggccgaaa actcatgatg atccgtgcag cagcagggat
     3001 gacattaaca atgggatctt tggcttttgt accaaacgcg tattggcttt tgatcatgcg
     3061 gttttggaat gggattttgt ctggatatat tccaaatgcc acagcgatga ttgcttcaca
     3121 ggcacctaga gaaaagagcg gatgggcgtt aggaacattg tctaccggag cgattgctgg
     3181 aaatctgatc ggaccttcaa tgggcggtgc actggctcag tggtttggta tggaaaatgt
     3241 attcttgatc acaggggctt tgttgatgat cacaacggta ttgaccattt tcttagtcaa
     3301 agaagatttc catccaatcg agaaaaaaga tctgataagc accaaagaaa ttttttcaaa
     3361 aatggatcat ctctctattt tgatcggtct cttcattacg accttgattt tacagatagg
     3421 aatcactacg atcagcccta ttttgacctt atatattcgt gaattgagcg gaagtacaga
     3481 aaatatcctt tttgtcagcg gcttgattgt ttcgatagct ggtgtttccg ctgtcttttc
     3541 ttcaccgaaa ctaggaaaac taggggataa gattgggaat caaaaagttc taattggagg
     3601 actcatttta tcattttgct gttatttacc tatggcattc gtcactacac cgctccaatt
     3661 aggtatactt cgctttattt taggcttttc aactggcgct ttgatgcctt ctgtcaatac
     3721 actgatcagt aagattacgc ctcaagaagg agtcagccga atctatagct acaatcagat
     3781 gtttagcaac tttggacaag ttttaggtcc catgctagga tcgacagtcg cgcatgctta
     3841 taattacagt gctgttttta ttgtgacaag tttgtttgtt ctgtcaaata ttcttctttc
     3901 tttattcaac tttcgtaaag ttcttcgcag cagattataa tggtggtgag gagtagaaaa
     3961 taaaaaagag cttgagaaat ctcaagctct tggctgtttt tttacgaatg ggcagaggtt
     4021 tcttttcttg gcgcaactgc accaatcaaa aggataatga cacccgcaat gaatgaaatg
     4081 attgttgtca aagtaaaatc atatgttccg cttgttaatg cagcaccaat ataaccgact
     4141 acttgaccta gaacgacagc ccagaataat gtaacgatat atcgcataaa gaacacctct
     4201 tttctatctt aattttacca gattttcttt gaatgtaaag aaacgagacc aaatctcaat
     4261 aaaatttgag ttcttgcgaa agaactcatt cctacagatt acaagcaagc aaatgaagtg
     4321 gaataatcaa cttcagcgcc tgctatctta atgaaagtaa aaggatcaaa ccttttaacg
     4381 ctagtgaatt ttaacgaaaa aaaaggcgga atgcaagatg tttttcccac aactttatac
     4441 aattacttct tattctcttt tacaaagtac gatacgtatt cgagaatatg tacaagaagc
     4501 aaaaaaacaa ggctacactt cattagccat aacggataaa gatgtcttat acggtgcacc
     4561 tgaattctat cgtatttgtg tagaagaagg agtacagcca atcattggat tacatcttag
     4621 ttatacttat gaagaaaaaa attatggctt gcttgcgtac gcaaaagatg aaataggtta
     4681 tcagcagctg atgaaacttt ccagccgaaa aatgatccaa gaaaaattgg aacttgcaga
     4741 aatgacagaa accgaccatc tagcgtttgt tgttccggca aatcattctg tttctgaggc
     4801 tttcaataaa gaggataact ttttcggtca ttggcagttt ttacttgaaa atgtttttac
     4861 tagaaatttt tatatcggct tgacagaaaa cacgcctgat caattgcctg aatggtatca
     4921 gtatgtgata aaagaaaatt attcgctttg tgcattacat cccatcgcta gtttacaaca
     4981 agaagaactt tttgcacttg aagtgatgaa acatatcaaa gagggaagcc aaataccttt
     5041 agaaaattta tctgcatctt taccactaac agcaaatgtc tatcttcttt cagaacaaga
     5101 aatgatcaaa cgattcgaaa aagcgggtct ttcccaagct gtaataggcg cccagcgttt
     5161 agctgaatcg atttcatttg aattccagtt ccatcagaaa ttacttccgc attatccagt
     5221 tcctaatgga aaacaagctg gagaatattt aagagagtta tgctattcgc aagtggaacg
     5281 ccgaatcact gactatacaa aggaatacca agaacgtttg gactacgagt tatctgtcat
     5341 ccatcaaatg ggattcgatg attatttctt gatcgtatgg gatgtaatgg cttttgctca
     5401 tagaaacaaa atcgttaccg gtgcaggtcg tggttctgct gcgggttcat tagtagccta
     5461 tgtgttagaa atcacagatg tggatccatt agaatatgat ttgctgttcg aacgcttttt
     5521 aaaccccgaa cgctttacga tgccagatat cgatttggat attcctgaca atcgacgtga
     5581 agaagtattg aattatgttc gagaaaagta tggacaatat catatggcac aaatcgcaac
     5641 atttggcaca atggcagcaa aaatggttct tagagatgca gctagagtgt ttggtttatc
     5701 gcaaagtgaa gcaaaccgct ggtcaaaagc aatacccaat caattgaaaa tcacattgac
     5761 ccaagcttat aaaacttcgc atcaattagt agaattagtt caggcaagcg aaaaaaacca
     5821 acttttattc aaaactgcag tgattttaga aggattgcca agacatgttt cgactcacgc
     5881 agcaggtgta gttatcagcg ataagaatct acttgaacta gttccgctcc aacgcggttc
     5941 tgatgaagct tttctgaccc agtatacgat gaatgaggta gaagcaatcg gtcttttgaa
     6001 aatggacttt ttaggactac gcaacttatc gattattgat tttactttga aagctgttaa
     6061 gcgagtagaa gggtatgaga tccgattaaa agagatcccg ctaaatgatg caaaaacgct
     6121 gctcttgttt caacgaggcg aaacctcagg agtatttcaa tttgaatctg ctggtatccg
     6181 gaacgtttta cgaagattag atccagaaaa catcgaagat attgccgcag tcaatgcatt
     6241 gtatcgacca ggccctatgc aaaatataga taccttcatt gccaggaaga aaggaaaaga
     6301 agccattcgc tacccagatg attcactgat cccgattttg aaaaacacat atggagtgat
     6361 cgtctatcag gaacaaatca tgcagatcgc ctcgactatg gctggattta cattagggca
     6421 gtcagatatt ctgcgacggg cagtgagtaa aaagaaaaaa gacgtattag atgaagaaaa
     6481 gtcgcatttt gtatcaggag cattacaaca gggatattcg gaaaaaacag cagcgaccgt
     6541 atatgaatat atcgaaaaat ttgcaaacta tggattcaat cggtcacatg catttgctta
     6601 ttcattcgtg ggattccaaa tggcgtatct aaaagcccat catccaggtg ctttctttac
     6661 cagcctgatg aattctgttc ggcataacac atcaaaattg aaagaatata ttgcagaagc
     6721 acgtaaaaat aaactcaaac tttcctcgcc gtccattaat caaagtaatt ccagttttga
     6781 gttggtcaat aaggaagaaa tcagattcgg actgacagcg ataaaaggta ttcggcgtga
     6841 ttttgtagaa gatatattaa acgaaagaaa acaaaatggc ccgttccagt cagtggatca
     6901 attcctcata cggatcgata agcgttggct gaaattagag ttactgcaat cactgacagc
     6961 agtaggagtt tttgatgaat tatctcctaa caggaaacaa ttgatgcttg atctcgaagg
     7021 aaaaatccaa aatatcgttt acagtggtgg aagtcttgac ttgctgggaa tcatggcatt
     7081 aaaagaagaa gaagtcgctg actatacact agaagaacgc ttgaagctgg aagaggagta
     7141 cttaggtatt tatttgtcag gtcatcctgc agaagggttt gatcgtcttc gtttagctaa
     7201 acaagttcag ctgattacag atatcgtccc taatcaacca gtcaatttat tagtgatgat
     7261 caaggaagtt agagaaattc ggacaaaaaa aggagaactg atggcctttg ttgaaggaac
     7321 cgacagtagt ggagaaattt ctgtcacagt ttttccaact ctttatcgta aatatcgtaa
     7381 tttgtttgcc gttgatcgag tgatctttgt tcaagggcgg agcgaaatca gcaaatataa
     7441 tcaggaactg caactaattg gagaaagctt tgctgatcct aaccagttag aagcccagta
     7501 tccttcacaa acttgctatt tgcgtattac agaagaacgg gaagatcccg agataatgaa
     7561 acaattacaa gtgatttttc agaaacaccc aggatatata ccagtagtta tgtatcacga
     7621 aaaaacgcaa cgaaaagtag ttctgtcaga tgcttattgg gtggatgaca gcaagagtat
     7681 aaagcggcaa cttatttatc tgcttggcga agataatgtg gttttcaaat aacttacggt
     7741 aaaaaatact acttgctttc attttttttc atttttttat ccgtaaatca agacaagtga
     7801 gaaaaataat gttagaatgt tagtcgtggt taacgcaaaa atggttgtaa acctaagtca
     7861 tacttaggat aaagtatttt aatgaggtga atgtttatta tgaaacgcat cggaattttg
     7921 accagtggcg gagacgcacc tggaatgaat gcagctgttc gtgccgttgt tcgtaaaggt
     7981 atttacgaag gactggaagt atacgggatc aattatggtt ttgccggttt agttgctgga
     8041 gatattcgtc gtcttgatgt ggcagatgta ggtgacaaga tccaacgtgg tggtacattc
     8101 ttgtattctg cacgttatcc agaatttgca actgaagaag gtcaattaaa aggaatcgaa
     8161 caattgaaaa aattcggaat cgaaggtcta gtggttatcg gaggagacgg ctcttatcat
     8221 ggcgcaatgg ctttgacaaa acgcggtttc ccagcagtag gtattcctgg aacaatcgat
     8281 aatgatattc ctgggactga tttcacaatc ggttttgata cagcaatcaa tacagtacta
     8341 gaatcaattg accgtattcg tgacacagcg acttctcatg ttcgtacatt cgttatcgaa
     8401 gtaatgggac gcaatgcagg agacatcgct ttatggtcag gtgtggctgg cggagcggat
     8461 gaaatcatca tcccagaaca tgattttgat atggcttcag ttgctaaaaa aatccaagaa
     8521 ggccgcgatc gcgggaagaa acattgcttg atcatcttgg ctgaaggtgt aatgggcgga
     8581 aatgaattcg ctgagaaact ttcagaattt ggtgactatc atacacgtgt atctatcttg
     8641 ggacacgttg tccgtggtgg agcaccaagc gcacgcgacc gcgtgttggc aagtaaattc
     8701 ggtgcttacg ctgtcgaatt gcttcaagaa ggaaaaggtg gattatgtgt cggtatccat
     8761 gacaacgaaa tcgttgcgtc tgacatcatt gatacacttg aaaacaacaa acataaacca
     8821 gacttatcac tatatgatct aaataattca ctttcatttt aagagtgaaa gaaaccaagc
     8881 tatttaagct gtgtacagct ttaaataaac aaaattgaat gggagagttt tttaaatgaa
     8941 aaaaaccaaa atcgttagta cattaggacc agcaagtaac tcagtagaaa ttatttctca
     9001 attgattgaa tctggggcaa atgtcttccg ctttaatttt tctcatggtg accatgaaga
     9061 acaattatca cgtatgacta tggtccgtga agcagttaaa aagacaggaa aagatgtcgg
     9121 tattctttta gatacaaaag gagctgaaat ccgtacaact gttcaaggca caacagaagc
     9181 tgattttggt cgtgcaggat acatcaaatt tgaagtagga gatcaaacac gcatctctat
     9241 ggatcctgaa catgtaggtt caaaagaaaa aatcgcggtt acttacccag gattatttga
     9301 cgatgttcac gttggcggac acattttatt tgatgatggt ttgatcgata tgcaaatcat
     9361 tgaaaaagac gaagcaaacc gtgaattagt cgtagaagtt aaaaatgcag gtatgctagg
     9421 atcacgtaaa ggggtaaatg caccaggcgt ttctattagt ttgccaggta ttactccaaa
     9481 agatgctgac gatattcgtt ttggtttaga caacgatatc gactttatcg ctgcaagttt
     9541 tgtacgtaaa gcacaagacg ttctagatat ccgcgaaatc ttagaagaaa aagacatgac
     9601 tcatgttcaa atcttcccta aaatcgaatc tcaagaaggt atcgacaaca ttgacgaaat
     9661 catcaaagtt tctgacggtg ttatgattgc ccgcggagat atgggtgttg aaatcccagc
     9721 tgaactagta ccaatggttc aaaaacgcat tatcaaaaaa tgtaatgctg ctggtatccc
     9781 agttatcact gctacacaaa tgttagaatc aatgcaagaa aacccacgtc caacacgtgc
     9841 ggaagcttct gacgttgcta acgctgtatt tgatggcaca gatgcaacaa tgctatctgg
     9901 tgaatctgca aacggggact acccagttga agctgtttca acaatggcac gtatcgacca
     9961 agaagctgaa aatgcattat cagaattagg tacattccaa ttgaacgaat tcgataaaac
    10021 agatgtaact gaaacaatcg gtttatctgt agctcgtgct gcaaaaaatc taggcgtgaa
    10081 aacaatcgtt gctgcaactg aatcaggata cactgcaaaa atgatttcaa aatatcgtcc
    10141 agatgcagat atcttggctg ttacttttga cgaacgcaca aaacgtggtt tgatgttaaa
    10201 ctggggcgtt tacccaacag ttgctgaaaa accatcaaca actgatgaaa tgtttgaact
    10261 agcagctaaa aaagctgttg aattaggttt cgcatcagaa ggcgatttaa tcttgatcac
    10321 tgctggtgta ccagttggtg aacgcggaac aactaacgtg atgaaaattc aaatgattgg
    10381 ttctaaatta ttagaagctc aaggcgttgg acaaaaatct gtcgttgcaa atgcagttat
    10441 tgcttcatct gctgaagaag ctgtaaaaaa agcaaaagac ggaatggttc tagttgtacc
    10501 atcaactgac aaagaatata tgcctgcaat cgaaaaagca gctgctgtta tcgttgaaga
    10561 aggcggattg acttctcacg ctgcagttgt aggaattgca caagatattc ctgtaatcgt
    10621 tggtgctaaa ggcgcaacaa caacaattac agaaggtgaa ttgattaccg ttgattcacg
    10681 tcgcggcatc gtttaccgtg gcgaaacaac agctatctaa tttagcttaa taaaaaataa
    10741 aaacagctct tcttttacga agagctgttt ttttgtgctg taacgaattc atggataact
    10801 tggactactt gttcttgaag aggcgtgacg atctgctgtg ttcgttttgc caatgaaatc
    10861 aagaagcgag gctgaacttc atctgaaaga gggaggcaaa ctaaatgatc ttcaggatgg
    10921 acagcaatct ctgccaaaaa accgataccc acattttctc ggaccatact ctttaaaatc
    10981 gtcaagtcat tgctttgata aacaactttt ggatgagtat gtgtttgttt agaaagctta
    11041 gtgaatgctg cggggtggac ataatgttcg ttcaatagta caaactgttc atctgctata
    11101 tctttgaaag agacagtatc ctgcttggaa agaggatgtg taggtggcac gacgatcatg
    11161 aaacgtttgt ccaaaagtaa ctctgtttct aaatattgat ccacgattgg ctgtgttgag
    11221 cctaatacag ctaaatcgat cctcccttgt cggatcatcc cgtataagtc ccgagagcct
    11281 ccatcggtaa tctcaatttg attcatcaat tcatgcttga taaagtaact tgacagttta
    11341 ggaaagtatt cattgccgat aataggaggc atgccaaaac gaagcttttt cttttgcaac
    11401 tgagtgattt cagctcttgc agtagaaatc tcttggagaa tggtttgtgc atggagaaac
    11461 agctgctttc cagaaggcgt gacgattaat tcgtgatgcg atcgatctct tgtaataagt
    11521 acggtgtcaa actctttttc aagacgttgt aatgcatatg taatagtagg ttggctcaca
    11581 cggaaataat tagccacttt cgtaaaattt ttttgtttga cgatttggac atagtattcg
    11641 atatctttcg tgttcatgaa gatcatccgc tcctttaatg gaataatgat tattgtaaat
    11701 gattctgagg atgatagcaa acagaggctt tctaataaag atttttctgt ttttttatga
    11761 actgcaaggt gtcaagaaaa tttcattgac aacatgcttt ttgccctgta taattgcttt
    11821 tgttgcttag gagtgatgaa aaatgaaatg gtctttattg gaattgagaa aataccagga
    11881 gacaccgtta acttttcatg agacgctcga cttgaaagcc gctctcatga agcgagacaa
    11941 tttaatactt gatgttgcgc cagtggaagt cgaaggtttg gtctcagttg ataagaaagg
    12001 ctatatcgtt cattacactg tgcagacgac tttgacagtt ccttcaacac gttcactaga
    12061 acctgttgaa ctgcccatgg atttttctgt agacgaagta ttcatgacag aagaacaatt
    12121 ccaaagtaga gatgaacaaa tgtctgcgga tgagattttg ctaattgaag gtccattatt
    12181 gaatttagca gagtcgattg aagacaacat cttattggcg attccaatgc gggtattgac
    12241 aaaagaagag gaagcagcaa cagaacttcc aaaaggcaat gattgggaag ttgtttccga
    12301 agaagaatac cagcgcagaa aaatggaaga agccgagaat aaaattgatc ctcgtcttgc
    12361 aaaactatct gaactttttg attctaaatc aaaagacgac gataacaagt aagattggaa
    12421 tatattgtgt ctaatttaga tacaagactt tacaaggagg tgtagcaaaa tggcagtacc
    12481 agctagaaga acatcaaaag ctaaaaaagc aaaacgtcgt acacactaca aattgacaat
    12541 caaagggtta aacgaatgtc caaactgtgg tgaaatgaaa aaaagccatc acgtatgtgc
    12601 aaattgtggt tactatgatg gtaaggacgt aatgtcaaaa gaagcttaat acattttaat
    12661 tagaaaatgt aaaacctcaa ggctaaccat ggagccttga ggtttatttt tttgtagtcg
    12721 gtaaataaaa aatatgttgt tctttagttt gcaatgtagc cgtgttaagc tataatgtaa
    12781 gagattaggg agaaatcccg tatgtaggag gagttcatat gtcaaaacaa caaatcggcg
    12841 ttgtcggtat ggccgttatg ggtaaaaatc tagccttgaa catagaaagc cgcggctatt
    12901 cagtggcttt attcaatcgt acaggggcta aaacaaccgc tgtagtagaa gaacacccag
    12961 ataaaaattt caaagcaaca tatacaatcg aagaatttgt agaatctatc gagaaaccac
    13021 gtcggatctt gctaatggtc aaagcaggac cggcaacaga tgcaacgatc caagagttgc
    13081 ttcctcacct tgataaaggc gatattttga ttgacggagg aaatacattc tttaaagata
    13141 cgatgcgtcg taatgaagag ttagccaact ctggcatcaa ctttatcggt acaggcgttt
    13201 ccggtggtga agaaggagct ttaaaaggac cttcaatcat gcctggtgga caaaaagaag
    13261 cctatgcgct agttgcacca atcttagagc aaatttctgc aaaagcagaa gacgaagcac
    13321 catgtgtcac atatattggc ccaaatggag ccggacatta tgtgaaaatg gtacacaacg
    13381 gtattgagta tggagatatg caactgattg ctgaatctta tgacttaatg aagaatattt
    13441 taaacctttc agtagaagaa atggctgata tctttaaaga atggaatcaa ggcgaattag
    13501 acagctattt gatagaaatc actgctgaca ttctgacacg taaagacgat gaaggaacag
    13561 gtaaaccagt agtagatgtg atccttgatg cagctgggaa taaaggaaca ggtaaatgga
    13621 caagccaaag cgcgcttgac ttaggtgtgc cacttccatt gatcactgaa tctgtatttg
    13681 cccgctatat ttctgcttat aaagaagaac gcgtacaagc aagcaagatt ttatctcgta
    13741 cgaacgattt tgagttcacg ggagacaaaa aagaattggt cgaaaaaatc cgagaagcgt
    13801 tgtatttcag taaaatcatg agttatgccc aaggatttgc tcaattacgt gtcgcttcaa
    13861 aagaatttga ttgggacttg ccatttggtg aaatcgcaaa aatctggcgc gctggatgta
    13921 tcatccgagc tcgattcttg caaaaaatta cggatgccta tgacaaaaat cctgagatcg
    13981 aaaatttatt gctagatgat tacttcgttg aaatcacgaa aaaatatcag caatcagtca
    14041 gagacgtcgt tgccttggct gtccaagctg gcgtacctgt accgactttc tcatcagcca
    14101 tcgcttactt cgattcatac agagcagaac gtctgcctgc aaatataatc caagcccaac
    14161 gcgattactt tggcgcacat acctatgaac gtgtcgacaa agaaggaatc ttccattact
    14221 catggtacca tgaagaataa tagtctttcg gctgttagga aatgagaaaa taaaaagagg
    14281 acgaaagagc tgaagtcgat tgttatgagt agacttcagc tcttttttaa aattgctatc
    14341 catgataaaa tgactataga tttttaagca tattatcggt ataatgatag agtttttaaa
    14401 aagccagtag aatagaaagg ataaaataat aaatgagcaa tattctaatc attgaagatg
    14461 aaaagaactt ggcacgattt gtcgagctag agttgaagca tgaagggtat aacgcagaag
    14521 tccactacaa cggccgaact ggtttagatg cggcattaaa taatgagtgg gatgccatat
    14581 tgttggatct gatgctccca gaattgaacg gtttagaagt ctgcagacgt gtacgccaag
    14641 tcaaaaatac accaatcatt atgatgactg caagagattc tgtgatcgat cgtgtatctg
    14701 gacttgacca cggagcagat gactacatcg tcaaaccatt tgctatcgaa gaattattag
    14761 cacgtcttcg tgcattgttg cgtcgaatcg atattgaagg cgataaaaat gtggctaaac
    14821 aaactactat tacttatcgc gatttgacta tcgaaaaaga aaaccgtgtc gtacgtcgcg
    14881 gaaatgaagt aattgaacta acaaaaagag aatacgagtt gctgcttact ttaatggaaa
    14941 acgtgaacgt ggtattagca cgtgacgttt tactaaataa agtgtgggga tacgaaacag
    15001 aagttgaaac aaacgtagtg gacgtatata ttcgttatct tcgcaacaaa attgacgttc
    15061 ccggggagga aagctatatc caaactgtac gcggaacagg ttatgtgatg cgctcgtgat
    15121 aaagccgaaa aaatcggaaa aaagagaact gaaagggccc tccttgacaa tcaagtgggc
    15181 ctttgcgagt tctttcttca tattcgttgt gtttacaatt ttcgctgtca ttacctataa
    15241 atcatctatc aatctgattg tggcaaaaga aagaaacaat gtagagcgta cgatttcaga
    15301 agtagcttct cgtttggcta actcggatga agaactgaca ttagtaaata cgtatcgtaa
    15361 tctgacgaaa gcgacaaatg acggagatga ggtcgtagat catacttcac tggtcgaagg
    15421 aaacttaatg aagatcgatt cctttatagc tgagctaggg cagccatcaa tggatcttta
    15481 tgtttatgat ttggacgaga acttgatttt taaaacccat gaaaacagtc gaaacctgat
    15541 tcagactaca cgtaaagttc caacgatcgt tacactagaa ggaaaaactg gctttttatc
    15601 tatccagcct atatattcta aaggtacaag agaaaagatc ggctatgcgc aaagcttcta
    15661 tgaattatct tctttctatg atattcgaaa taagctatta ttgactctta ttgttttaga
    15721 agttgtttct ttgatcttaa gtagtatttt aggtttcttt ttatcttctt atttcttaaa
    15781 accactcaag gtactcagag atacaatgga tactatacgt aaagatccgc aatcagatat
    15841 ccacatgcct gaaatcgaca caaatgatga attggcagat ttagctgaaa tattcaatga
    15901 gatgcttgac cgtatgcgtt tgtatattga acaacaagag caattcgtgg aagacgtatc
    15961 tcatgagtta aggacacctg ttgcaattat tgaagggcat cttagtctgc taaatcgttg
    16021 ggggaaagat gatcctgaga tattagaaga atcattaagc gccagcatgc aagaaattag
    16081 ccgtatgaaa agcttagttc aagagatgct agacttatca agagcagaac aagtagatgt
    16141 tcattatgcg aatgaaacaa ctaaaggaaa agaagtcacc tatcaagttt ataataattt
    16201 caagatatta tatccagact atgtgatcac tttagatgat gatttgacaa aagaagtgac
    16261 cctgcaaatt tatcgtaatc actttgaaca attaatcatt atcatattgg ataacgcagt
    16321 aaagtattca actacacgaa aagaagtcca tatctctatt tcttccactc tgaatgaatt
    16381 tgagatcgcg attcaggact ttggcgaagg aatacccaaa gaagacctta ataagatctt
    16441 caatcgtttt tatcgagtgg ataaagcaag agctagaacg aagggtggaa atggtctggg
    16501 gttgtctatc gctaaacaac tggttgaaaa ctataaagga cgtatcttag cagaaagtgt
    16561 agtagggcaa gggacaattt ttagaatctt tattcctatc gcaaaggcag aagacaagta
    16621 aagcatgtgc tttacttgtt tttttatata tccaacaaag aataaggtac aaaatacaag
    16681 caagttagaa attcagggat gtcattataa aaaaaactag cgaacaatta aatagaataa
    16741 catccgttaa ttaaacgtaa gtagctttta gatgaacgaa aaaacaatga aatgctgtaa
    16801 tattcgtgtt taaaaataat aaataaaaat agggaatttt ctattgcaat tttataaaga
    16861 gattgctata ttattatttg ttctaaatga ttcctttaag gtgtcactaa aaattataaa
    16921 aaatagggtt gacgcacttt tgatgtcatg ttataataac gaagtcgttt ggatgaggta
    16981 gctaataaag cttgatttta tcgaaaaaaa cttcgaaaaa gttgttgaca aataacaata
    17041 aagatgatat gataatcaag tcgctgctaa tgagtgacaa agacgtttag aaaaaataaa
    17101 caaagaagtt gttgacattc tcttctgaat ctgataagat taaagagttg ttgaaacaaa
    17161 aagattagac ctttgaaaac tgaacaaagt aagacaaacc aaatgtgtag ggcgtcttga
    17221 ttcaattcaa gacaacaaac atttttaaca agcaagcaat atgctagcaa acaaattgag
    17281 cttaacaatc gcaagattgt tcgaactttt tatgagagtt tgatcctggc tcaggacgaa
    17341 cgctggcggc gtgcctaata catgcaagtc gaacgcttct ttttccaccg gagcttgctc
    17401 caccggaaaa agaggagtgg cgaacgggtg agtaacacgt gggtaacctg cccatcagaa
    17461 ggggataaca cttggaaaca ggtgctaata ccgtataaca atcaaaaccg catggttttg
    17521 atttgaaagg cgctttc
//
LOCUS       DAYNVV010000053        17006 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.055, whole genome shotgun sequence.
ACCESSION   DAYNVV010000053 DAYNVV010000000
VERSION     DAYNVV010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17006
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.055"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..125)
                     /locus_tag="ACGXWR_002085"
     CDS             complement(<1..125)
                     /locus_tag="ACGXWR_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HFK0803617.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(229..540)
                     /locus_tag="ACGXWR_002086"
     CDS             complement(229..540)
                     /locus_tag="ACGXWR_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFK0803618.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(542..739)
                     /locus_tag="ACGXWR_002087"
     CDS             complement(542..739)
                     /locus_tag="ACGXWR_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFK0803619.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1133..2860)
                     /locus_tag="ACGXWR_002088"
     CDS             complement(1133..2860)
                     /locus_tag="ACGXWR_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HFK0803620.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2853..4046)
                     /locus_tag="ACGXWR_002089"
     CDS             complement(2853..4046)
                     /locus_tag="ACGXWR_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HFK0803621.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4233..4877)
                     /locus_tag="ACGXWR_002090"
     CDS             complement(4233..4877)
                     /locus_tag="ACGXWR_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFK0803622.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4971..5105)
                     /locus_tag="ACGXWR_002091"
     CDS             complement(4971..5105)
                     /locus_tag="ACGXWR_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HFK0803623.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5107..7239)
                     /gene="feoB"
                     /locus_tag="ACGXWR_002092"
     CDS             complement(5107..7239)
                     /gene="feoB"
                     /locus_tag="ACGXWR_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HFK0803624.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7236..7709)
                     /locus_tag="ACGXWR_002093"
     CDS             complement(7236..7709)
                     /locus_tag="ACGXWR_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFK0803625.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8110..8334
                     /gene="nrdH"
                     /locus_tag="ACGXWR_002094"
     CDS             8110..8334
                     /gene="nrdH"
                     /locus_tag="ACGXWR_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HFK0803626.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8493..10652
                     /gene="nrdE"
                     /locus_tag="ACGXWR_002095"
     CDS             8493..10652
                     /gene="nrdE"
                     /locus_tag="ACGXWR_002095"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFK0803627.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10702..11667
                     /gene="nrdF"
                     /locus_tag="ACGXWR_002096"
     CDS             10702..11667
                     /gene="nrdF"
                     /locus_tag="ACGXWR_002096"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFK0803628.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11756..12895)
                     /locus_tag="ACGXWR_002097"
     CDS             complement(11756..12895)
                     /locus_tag="ACGXWR_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFK0803629.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13204..13917)
                     /locus_tag="ACGXWR_002098"
     CDS             complement(13204..13917)
                     /locus_tag="ACGXWR_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HFK0803630.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14171..14872)
                     /gene="nagB"
                     /locus_tag="ACGXWR_002099"
     CDS             complement(14171..14872)
                     /gene="nagB"
                     /locus_tag="ACGXWR_002099"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HFK0803631.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15106..16638
                     /locus_tag="ACGXWR_002100"
     CDS             15106..16638
                     /locus_tag="ACGXWR_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFK0803632.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16829..>17006)
                     /locus_tag="ACGXWR_002101"
     CDS             complement(16829..>17006)
                     /locus_tag="ACGXWR_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFK0803633.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5278 a         3495 c         2910 g         5323 t
ORIGIN      
        1 gaaaaaacac attccactaa atttgatgcc ggttttcctt gaggttttgt tccagcacct
       61 cctttaattt ttttaagctc ttgatctgaa cattgtttag catttagtct atttttttct
      121 tccattacga ttccccctac aaactataaa tacttttatg tcactgattc aatataccta
      181 tttttctaat caaaaaattt tgagacatat ttaatattat aagtatcatt aaaattgaga
      241 tttatctcca taatctgctc gatataaacc atttattcca gcagttcttc caatttcact
      301 caaatttctt attaattcct cttgatattc agtgaatctt attttattag tataagcagt
      361 aaaatataga taattcacca atctatttat taaaggactg ggatctaatt catatttttg
      421 tttttctaat tttaaatata ccttttgtaa aacctcaaga atatcagaat atttaggatc
      481 tttacttata gatatatcat tatataattc atgaacaatt tgcttagcat tttttttcat
      541 tttagcactt ccctggaatt gctccaccta aaaaaccacc tatagacatt cctgcaatac
      601 aagtagttgc cttggcccaa tcgaccgtac atttattttt agtgcaatac actccatttc
      661 cataatattt tccactatga gtggtacccc catagataag ttgtgtctct ttaatagaca
      721 aaatttttaa atgtttcata atctaatcac ccctaaatta atgtttttag actattattc
      781 taacattcat taaatttcaa aaaacaattc cttcttgaaa cgtagcaaaa taattcctga
      841 ataagaattt aatcactttt aagtatataa actatgtata ttctttaata ttttttgaga
      901 atgcacttcg tacataataa actttaatca cattagtctt tcatacctac gatcgatctc
      961 tttgactcgc acccataaat tcataatagt ttgtcggcgt ctttgaacgt ttcgaagatg
     1021 agctacgcat tctctttttt tatagacaaa aaagatagag acgaacatgg agcttccaaa
     1081 tttggatatt tgatccaatt ttggaagctc catttatttc gtgtctgtct ttttattttt
     1141 tccagctttc gactaattct tggttctctt tgatccagtc ttttgctgct tgctgtggat
     1201 cttttccatt gttgatttcc aacataactt tttccatatc tttttctgac caatggaaat
     1261 tgtctaatac tttgtaagct tctggctggt cttctttcaa tccttttcga accatcgtat
     1321 ggatctgctc ttcgcttccc attccgtttt caggatcttc taagtatttc agatcatatt
     1381 tggcaaacat ccaatgaggt gtccatcctg taactacaat tggttcgtgt tttttgatcg
     1441 cttgacctag tgcaacggtc attgctcctg aagaagatgt ctctactttc cagtctttca
     1501 agttgtcata tttttggatc gtgttttcag cagccgtaac tacaccagct cctggctcga
     1561 ttcctatgat tttcttacct gcctgatcgg ttaactcatc gatcgaattt acatccatgt
     1621 aggctggcac tgctaaacca acttttgctc ctgtcaaatt ggcacctagg tcttcgactt
     1681 gatctttata ttgtgcatat tgtgaaccat gagttttagg tagccaagct gaaaccatgg
     1741 catctgactc gccatttgaa acagatttcc acatgattga attatctaat ggcgtcatcg
     1801 ttacatcata gcccatttgt ttcaatactt caccgactac atttgttgaa gcaacttctg
     1861 tatcccattc aacataagat aagttgatac gttttgtttc tttggcagat gaaaaactcc
     1921 ctataccaat cgcacctaag atcactacta ctacagcacc aatgatcagt ccttgacgtt
     1981 ttttactttt ctgtgttgtt gctcctgcag cttttttatt gtttggctgg ttcaaatgct
     2041 gtgtaaaacg gtcaatgatg attgctaaga taactaatgc aaccccgttg acaaatccat
     2101 tcccgacttg tgctctttgc aatgctgata atacgccgcg tcctaagccg ggtgcaccga
     2161 tcatagaggc aataacgacc attgaaagtg acagcattgt tgtttgattg atccctgcca
     2221 tgatcgtact tttagctaaa ggcaattcta gtttgaatag tttttgacga cttgtgctcc
     2281 cgaatgaatc agaagcttct actaattctt taggaacttg tcgaatccct aaattcgtaa
     2341 aacgaacggt tggtggcaga gcaaagatga ctgaggcaaa tacccctgga accatcccga
     2401 taccgaaaaa tgcaactgct ggaatcaaat aaacgaatcc tggcattgtc tgcataaagt
     2461 caaggatcgg tttgataata ctttgggctt tactgctttt tgccatcaag atccctaatg
     2521 gtaccccaat gatgatcgag atcacactag ataaaagaac aagtgtgaca gtattcatca
     2581 aatcattcca tagaccttgg ttataaataa accatagacc gattaatgtg aacaacgtaa
     2641 gtcctggacg tttcttagaa ataaagaaag ctgctaccgt caataacaag ataaacaaag
     2701 gagctggaat cactaacagt aaatttgtaa tccccgacat cactgcctgt ccaatcgttt
     2761 gtaaaaatga aaataggcca gaaaaagttg tcgtaaacca ttctgtgata ttttctaccc
     2821 agtttgccac tggtaattga tagttcaata gattattcat gttcactcac ctcgcttgtt
     2881 tctgctaatg cttcaatcac actacctcgg atgacgacac cttttaattt tccatcctct
     2941 acaactgcaa gtggagtcgg tgagtcataa ataatattga aaatatcact taccaccatg
     3001 tctttcccaa tcaccgtcac attttcatct aggaagtcga tcaatggacg tttttgcttc
     3061 ctagcttcta acgcttgatc tgcagtgatg atccctttca ggtgtctctt tctgtcaaca
     3121 gccatcagca tgctgacttc ttcattacgc atccttgtca atgcaacgtt tggtccatca
     3181 gattcgatat tcgtcgtcaa tgcaggtacc atgatgtttt gagccgtaag cactttggaa
     3241 cgatcgactt cttccacaaa ttcacgtaca taatcatttg ctggattggt caatatttct
     3301 tcacctgttc cgatctgcat gatttcgccg tctttcatca aggcgattct gtccccaatc
     3361 cgtaaagctt cattcaaatc atgggtaatg aaaataatcg ttttttgaac attggcttgc
     3421 aggtccagta attcgtcttg catttctcgc cggatcagcg gatcaagagc cgagaacgct
     3481 tcgtccatca gcaagatctc aggatcattt gctaaagctc tggctaggcc aacccgttgt
     3541 tgcatcccac cagataactg actaggatat tggtctttaa atgaaagcaa actagaattt
     3601 tctaatgctt tttctgcttt ttcttgtcgt tcttctttag gtacaccacg gacttctaac
     3661 ccgtattctg tattttccaa gatcgttcga tgtggaaaca gaccgaagtt ttggaaaacc
     3721 atattgattt tatgacgacg gacttctcgc aattcttctt tgcttaactt cgatacatct
     3781 tctccatcaa tatagatact gcccgaagtt ggctcaatca gacgattcaa tagacggatc
     3841 aatgtggatt tcccactccc ggaaagcccc atgatcacga agatttctcc ttcttttacg
     3901 tcaaaattca cgtcatacac accaaccgtt gcaccggttt tctttaaaat ctccgttttc
     3961 ggctggtgat cattcatcat atctaaagcg gcttgtgtct ttttaccaaa tatctttgtt
     4021 aaatgtttta cttctacttt taccaaacaa attctccttt tttatgtaaa ttcatttttc
     4081 tttctgaaaa aagtgaccac actatgttaa catcatgtag tcactttgtc aaaaatgaaa
     4141 gaaatttgct tgtccaaact gaaaaaaact tggctaaatc tttgtaaata aaaggtttag
     4201 ccaagttaat atttttttaa tatttcacac aatcattctg caagctgatg ctccgggtaa
     4261 aaaaagtttg tcatacgctg tagtgtatat tcatttccaa taaaatgaac gatgtcccct
     4321 gccgtaaatt tagcataggg gccaggtgaa acaagcagtt cttcattatg agaaattgcg
     4381 ataactgtgg cgccagtcgc ctgccagata ttcaactcgc taattgaacg gtccagatgc
     4441 attgcttttt ctgataaaga taattcaaac ggaagtaaag gattcatctt atgtattcgc
     4501 ttcgtttgat tgaccagctg atccaataat tgagaaaaat gattcagctc atcttgttgc
     4561 ttctccacac ttgccatgat ttctgctttt gtatcttgga tggattgtac atcttgatat
     4621 tgcaatagga aatcttttgc tttttccttc gaagcaacaa atgccccact tccatgccgt
     4681 acttccatga ttccaagatc taccagcaca ttgatagcct tgcgggtagt ctcaggagaa
     4741 gcattgtacg tactggcaag tgttgagcgg gcatggatct tctcacccac tttatatcgg
     4801 ttttcaacga tacgttcggc taaatcaaca gcaatctgct ggtagcgcgg gcggacgatt
     4861 tttttctttc cagacatttt ctttcctctt tcttttttta ctttccctca tcttactatg
     4921 ctctagcaaa ataagcaaaa aaggggagaa tagcctcttg caacgactga tcatcgcttg
     4981 atctgttcct tttttactgg gcaagctgtt tgacagtcat cacaattctt accggatttt
     5041 aaacgagtat agacaattgc gcctgcactt ccaaagatta acacacttaa taagaatgtc
     5101 gccatcctat tcctctcctt ctaatgacaa tatagtataa aactggttct tggattttgg
     5161 ctgacggaac aaaacataaa cgagtcctat catcagtaaa atagcaagat acgtccctaa
     5221 cgctacctgt ccaccctcca ataagtgtcc caactgataa atcacaaaac taactaaata
     5281 agctaaaccg cattgatagc ctatggcgat ccaagtccat ttcttggcat tcatttcccg
     5341 atggatagcc ccaattgccg caaaacaagg cgcacaaagt aaattgaagg ctaacaatga
     5401 ataagctgct gcgggagtat atgtgtgttg tagcacttgc cagatttctc tgccattttc
     5461 ggatacttcc gcatgaccaa acaaaatacc aaatgtgcca ataatatttt ctttagcgac
     5521 caatcctgta atcgctgcga ctgttccttg ccagtttccc caaccaagcg gctgaaaaac
     5581 aactgccagg attcgcccga aaaaggctaa gatactttgg tcttcagaaa caggttgagc
     5641 ataaaaatta taagaagagc tgaaccagat cacgatacta gaaacaaaga taatcgttcc
     5701 tgctttttta acaaaagact tgctgcggtc ataggtttgt cttaggaccg ctgaccattg
     5761 aggaaaatga tatgcgggca attccatgat aaaaggagct gtatctccag caaacaaacg
     5821 tgtttttttc aagctgattc cagagaaaat aattgcagtc ataccaagaa aataggcaga
     5881 aggagctacc caagattgat gaggaaaaaa ggcccctgct actaaggcaa taatcggcaa
     5941 ctttgcagaa caaggcatga aggttgtgac catgatcgtc aaacgacgat cttgctcgtt
     6001 ttcaatcgtg cgactggcca tgacgcctgg cactccacat cctgtagcaa tcagcatagg
     6061 aatgaaggat tttcctgaaa gaccgaattt cctgaaaagt cgatccatga caaaagcgat
     6121 cctcgccata tatccgcagt cttccagaaa gctcaagcat aaaaacaata taatcaattg
     6181 cggtagaaat cctaacactg ctcccacgcc tgcgatgatg ccgttcaaga tcagctcctg
     6241 catccatccc gctacttgcc attcagctaa caatctgcca acatgttctg gtaaccatgt
     6301 accaaacaat gtgtcattga tccaatctgt ccccattgtt cctactgttt gaatagccag
     6361 ataatagatc agccacatca caaatgcgaa gatcggcaag gctaaccaac gattcgttgc
     6421 aatctgatcg attttgtcac tcatcgataa ttggaaagaa tcatttgaca caacacagag
     6481 tgtacatagt tgggtaataa attcataacg ttcattgacc agaatcgtct cactatcgtc
     6541 gtccaatagt ttctctgtta actggatcag ttgctcgatc tctttttgct gagaaactgc
     6601 tatctcgtaa tcctctctta ccttctgatc tcgttcaaaa tatttcattg cataccagcg
     6661 tttcttgccg ctttgttctc ctagtacatc ttcaatttca tgtaaagctg cttctaaacg
     6721 tggatcatat gtacagggaa caggaataga aggccgcttt tttgcagact cctgaatctt
     6781 ttcgattagt ttttcgattc cttgcttttt caatacgctg attggtaaaa ctggtacacc
     6841 aagaccatag gaaagctttt ctagattgat tttttttcct tcttttttga tgacatccat
     6901 catattcaga ccaatgatca taggaatgtc taaatccaat aactgcgtag ttaaataaag
     6961 atttcgttct aaattggtag catcaataat gttgatgatc agttcaggct gttcctgaac
     7021 caaataatct cttgcaatca cttcttctgg tgtataagga gacaaagaat agatgccggg
     7081 taggtcctga atatgaatgt tcggattttt tttcaacgat ccttcttttt tttctactgt
     7141 tacgcccggc caattcccta catattgatt cgaaccagtc aagagattga acaagctagt
     7201 tttcccgctg tttggatttc cgactaacgc gatattcatt ctttttcctc cctttgtatc
     7261 aagattagtt cggcctctga ctttcgtaac gtcagttcat accctcgcac tgtcagttcg
     7321 attggatctc ccagaggggc tagttttcgg ataactattt ttacatttcg cgtcaatccc
     7381 atatccatta accgtcgctt cactgcgcct tgtccgtgga ttgctacgac gatcccagtc
     7441 tctcctgctt ttaattgatc aagagaagtc cagctttcag aggaagcagt ctttttattg
     7501 acaaagattt gacctagtat ttcccgactt actgccactc gatgactttt taccagtaaa
     7561 atggcattgt tgcctgataa attgacgacg acgattttac ttccggcaac gatcccgata
     7621 ttttgcaaat ggcgttttgt tttttcttct gtttcgattc gttcgacttg ataaacgaaa
     7681 ttctgctttg cctgcgctaa ggtctgcata ttgattcctc tcttgtgaaa taaatcatgt
     7741 attaaaatca ttcattatat gttctaattt tcttacgtgt tacgcaaata aatgagaatc
     7801 attctcacat agaatactct cggtaattga gaatgtcaat tatacttgtg atattatgag
     7861 cgaatcttta gtattgatag ataaaaatga gaaaaaaata tttcttcata gttttccaca
     7921 attttttctc tattaaattt gctattttcc cacacgatac ttgttttcag ctcttttttc
     7981 aaaaacacaa aacttagtat tccacagttt ccacaacaca atatgtagtg tttgttgttt
     8041 gactttttta ctaagagttt tatactatct attatagata ataagaatgt gttagaggag
     8101 gcactcacca tgaacgtaaa aatcttttct aaaaataatt gtatgcaatg taagatggtc
     8161 aaacggtttt taacagaaaa tcaaattgct tttgaagaag tcaatatcga tgaacagcct
     8221 gaagcagtag actggttgaa agcacaagga ttccaaagtg ttcctgtcat tacttctgat
     8281 gcagaaacag ttatcggatt ccgtcctgat cagttgcgta aacttgccag ctaacatgac
     8341 taaaagaatc aaaacgtgat acatggattt gaagggcttg agacagcacc agtttttgtc
     8401 gcaaacttcc aaatcctttt ttaaagctta aaaacaatgc aatgatttgc aatcaagcat
     8461 catcaaatac gaaatgaagg ttgggcgtac gtatgagtct taaaaattta caagatgtca
     8521 gttatttcaa gctgaataat gaaatcaatc ggccagtcaa tggtcaaatc cctttgaata
     8581 aggataaaga agctttagtt gccttttttg aggaaaatgt caaaccaaat acgatgactt
     8641 ttccatctat tatggaaaaa atcaattact tgatcgatca agaatatata gaagcagaat
     8701 tcattcaatt gtattcacca tcatttattg aaaagctata tcaatttttg gacgagcaac
     8761 atttttcttt caaatctttt atggctgctt acaaatttta ttctcaatat gcgttgaaaa
     8821 ccaacgacgg ttccgcttat ctggaaactt atgaagatcg agtagccttc aatgcgcttt
     8881 actttgcgaa cggggatgaa gaattagcac ttgctcttgc agacgaaatg atccatcaac
     8941 gatatcagcc agctacacct tctttcttga atgctggacg taaacgtcgg ggcgaattgg
     9001 tgtcttgttt cttgactcaa gtcactgacg atatgaactc tatcgggcgc tcaatcaact
     9061 ctgctttgca attgtcccgt attggtggcg gcgtagggat tactttatca aatcttcgtg
     9121 aagccggcgc tcctatcaaa ggatatgagg gtgctgcaag tggtgtcgtt ccagtcatga
     9181 aattattcga agatagtttc agctattcta atcaattagg tcagcgtcaa ggagctggcg
     9241 tggtttattt gaacgttttc catccagaca ttattgcttt cctttcagca aaaaaagaaa
     9301 atgcagatga aaagattcgc gtaaaaactc tttctcttgg cgtgatcgta cctgataaat
     9361 tttatgaatt gacacgtaaa aacgaagata tgtatttatt tagtccatat agtgtcgaaa
     9421 aagaatatgg tgtcccattc tcttatgtaa atattacagc tgagtatgat catctagttg
     9481 caaatccaaa cattcgcaaa caaaaaatca aagcgcgtga tcttgaaaat gaaatctcaa
     9541 aattacaaca agaatctggc tatccttacg taatcaatat tgatacagcg aaccgcgaga
     9601 atccaatcga tggcaagatc atcatgagta atttatgttc agagatttta caagttcaaa
     9661 cgccttctgt gattaacggc aaacaggaat atgaagtatt aggaacagat atctcatgta
     9721 acttaggctc gacaaatatc gtgaatttga tgcaaagccc taactttggt caatctgtgc
     9781 gtacgatgac tcgtgcattg acatttatta cagatgcatc tgatatcgat gtcgtaccac
     9841 cgatccaaaa cggaaataag ctgaatcata cgattggatt aggtgccatg ggcttacaca
     9901 cttatcttgc aaaagaacaa atggaatatg gctcagagga ttcattagac tttacaaata
     9961 tttacttcat gctgttgaat tattggacac ttgttgaaag caacaatatc gctcgtgaaa
    10021 gaaaacaagt tttccataat tttgaaaaat cagcttatgc tgacggcact tatttcgaaa
    10081 aatacgtaac tggagaattc cagccaaaat cagaaaaagt caaagcattg tttgaaggca
    10141 tttttatccc aactgctgaa gattggaatg ctttgaaaca agcagtaatg aaagatggac
    10201 tgtatcatca aaatcgcttg gcagtagcac caaatggctc aatttcatat atcaacgata
    10261 cgagtgcaag tattcatcct atcactcgca tgatcgaaga acgccaagag aagaaaatcg
    10321 gtaaaattta ttacccagcg ccttatctat ccaatgagac gattccgtat tacacttctg
    10381 cttatgatat ggacatgcgt aaagtaatcg atgtttatgc aacggcacaa caacacgtcg
    10441 atcaaggcat gagtttgact ttattcatgc gttctgaaat cccagaaggc atttatgaat
    10501 ggaagacaac aacgaagcaa acgacacgtg atttgaatat tttaagacat tacgctttcc
    10561 acaaaggaat caaatccatt tattacgtac gtacctttac tgatgatgca gaagaaatcg
    10621 gaagcaatca atgtgaaagc tgcgtgatct aatatcatag atagattcgc ttattcatat
    10681 tttaattaaa ggagcattct catgtcagaa acatattatg aagcaataaa ctggaatgaa
    10741 attgaagata tcattgataa atccacttgg gagaagctga cagagcaatt ttggctagat
    10801 acacgtatcc cactttcaaa tgacctagat gattggcgta cattgtctca attggaaaaa
    10861 gatacagtag gacatgtatt tggcggtttg acactgctag atactgtcca atctgaaagt
    10921 ggcatggatc agttgcgtaa agatgtccgc actccccatg aagaagccgt tttgaacaat
    10981 attcaattca tggaatccgt tcatgccaaa agttattctt ctatttttag tacactgaat
    11041 acgaaaaaag aaatcgaaga aatttttgac tggacaaata cgaatcctta tctgcaaaaa
    11101 aaagctgagc gtatcaatga aatctacaaa cacggtacac cgctagaaaa gaaaattgcc
    11161 agcgtctttt tagaaacatt cttgttctat tcaggttttt atactcctct ttattattta
    11221 ggaaacaaca aattggctaa cgtagcagag atcatcaaac taatcatccg agatgaatct
    11281 gtacatggaa cctacatcgg ttacaaattc caattaggat tcaacgagtt acctgaagca
    11341 gaacaagaaa cgttaaaaga ctggatgtac aatcttcttt atgagcttta cgaaaacgaa
    11401 gaacgttata cagaagaatt atacgatcca atcggctgga cagaagaagt caagacattc
    11461 ctacgctata atgccaacaa agcattgatg aacctaggga tggatccact ctttccagat
    11521 actgccaatg atgtcaaccc aatcgtaatg aacgggattt caacaggcac aagcaaccat
    11581 gacttcttct cacaagtcgg aaacggctat ttgttaggtc atgtagaagc gatgaaagac
    11641 gacgattatt tgattggatt ggaataagga tttattttaa ttcaaaaatt tttcgaaaaa
    11701 taaaaagagt ttagcgtaca gatattttaa atgtacactg aactcttttt tatgcttatt
    11761 cacttgtttc ttccagcact tttggactgt ctaacttttc cgaaacatgt tccattcttc
    11821 tcaataaata gattttccgg atatttaata ttatcgtctt aatcactgca tagacaggta
    11881 tgcaaatcag catgcctaat attcctgcga cacttcctgc tccaatcaat accaagatga
    11941 tcgtcaaagg atggatattc attgatttcc caaataacaa cggcttgatc aaatttccat
    12001 ctaattgttg gatcactaaa atcgacaacg ccatatacaa agcttgaaat ggagagataa
    12061 acaaaccgac aatgattgct ggtaccgctc caataaaagg gccgacatac gggataatat
    12121 tcgtgattcc gcaaatgacc gcaagcaaca agctataagg ctgatcgaat attctcattg
    12181 ccaaaaagct cattacacca ataatcaaag catctaagat cgtactgctg atataggcag
    12241 ataatgtttc gtttaattct tttaccgttt ggcgtaactc tttacgaatc gctttcggaa
    12301 agaagtgaga caacgcatca ataaatttgt gcccatcctt gaacataaat agcaaaataa
    12361 atggaacggt aaataacaaa ataaaaaatt gcatcataaa tgaaatgatt tttgagacac
    12421 ttgcagataa actgactaat atgatattga acaaattact aagagataaa tttgctgatg
    12481 ctaattgttc ttccaaattg aaatttttaa actcttcccg ctgcgccaat tcatttaacc
    12541 atttgcttgt ttcatctgca tacattggca agctctgggt caattgaatt gtctgttcca
    12601 ttaactgagg cactacattc atgacagtta aaacaactaa aatgattacg accaaaaacg
    12661 tcaataaaaa accgaacact ctcgggatcc gatgcttttc gagaaaaaca acgattggat
    12721 cgaacatata atagataaaa ccagcaacaa gcaatggtaa aaaaattgcc gaaagcattt
    12781 tcaatattgg actaaaaata ttcggcattt gtaaaataaa gtacacgccg atgatcgtga
    12841 gtactagctc cactgtccag aaaaataatt ttgattgttt aaaacgtgat tgcatacatc
    12901 tcctccaagg tcctttgata cttctattct atcatttaac aaagagttac gcgctgagat
    12961 tttcatttgc ttaaaaaaaa caaaaaaaat aaacatattt taatgagtag acgagtactt
    13021 aaacaaaaac acggtttgga gtagtgacaa aaattatact gcagtccctt tttccaaata
    13081 aacggtgttc aaaagcttgc atcttcgtaa taagcccagc caaacgaaaa atataaggaa
    13141 ctatttttat ttggctgggc ttattacttg atgtaggaca tctattttac aacctcagat
    13201 catttattgc gcaatactga ctaaatgcaa ctttgtgata tttttgtgta cggacaactc
    13261 ctcgatcaca tcggcataag tgagcccttt tggaagatca atcgtataga tatttttgta
    13321 cactcggtag tcatcaacga attttacgtc aaaattcaca tcttcgatta cgatattttt
    13381 ctcttcaaaa taatcggtaa gaaaatcttt ggtttctttt ctatggataa attggatttc
    13441 taacttttta gtcgtaggta catggatcac gcgtttcact actgtgagtg caatagcaat
    13501 cccgataaaa ctgatgatcg caatggaata gtaacccatg ccgatggcga tccctaatcc
    13561 agcaattgcc cataaagaag cggcagtcgt aagtcccgtc accgattgtt tcgtgacgat
    13621 gatcgttccc gcgcctaaga aaccgacacc actcaccact tgagcaatca gccttgcttc
    13681 atctgaacga atcgttccag caagctgtgg atactctaaa gcatctctta atgcaccact
    13741 agcgatctca acttggatca atgcaatgat acatgctccc atacaaacta aaatatgcgt
    13801 acgcatacct gctggacgat ttttatattg tcgttcaaaa ccgattgctc cgccaaatag
    13861 catagcgatc cctaaacgta aaataatctc tggaattgtc aataccatat cattcatcta
    13921 aacaccctcc agtccaatat atcatgtctg aaaggagcag acaaaaaaag tgcaattttt
    13981 acctcttacg aaaaaaggac tgtgacaaaa tttttgtcat agtccttttt atgaataaac
    14041 ggtgttcaat cagctgaccc tcggtattac tcaacaaacg gcaaaatatg gggagctatt
    14101 tttcctttgt cttctctaat actcaggtca aaacgctgat ttcacaacct ctttagccta
    14161 ctattgaaaa ttacaactta cttgctgctt cttcatcgat gatcacaaca acattgtcgt
    14221 gattttgcaa tacacttgct ggcaaatgat tcgttacagg tccttcaatc atccctttga
    14281 ttgcatcagc tttgctttcg ccaaatgcca tcaagacgat ttctttactt ttcataattg
    14341 aaccgattcc cattgaaaca gcttttgttg gtacatcttc tgctttatcg aagaatcgtt
    14401 tgtttgcatt gattgttgat tctgttaagt caactactga agtcgttccg tcaaatgaag
    14461 caccaggttc attgaaaccg atatgtccat tttgcccgat tcctaagatt tggatatcga
    14521 ttggatgtgc atcgatgatt tgatcatact ttttgcatgc tgcttccaga tcttctgctt
    14581 ttccatctgg tacaaacgtt tctttgaatg gttttttatc aaataattgg acatccatga
    14641 aatgacggta gctttgttca tctgaaccgc ctagtccaac gtactcatct aagtttacag
    14701 aagtcatttc actgaaatcc aaatcgcttg aagtcatttc tttatataaa gtaactggtg
    14761 tgcttcctgt tgccaatcct aatacttttg cacctttgtt cataccttct ttgatgattt
    14821 caaatgcttt ttttccgcct tcttcagcgt tttttacacg aatgatttcc atagtgattg
    14881 ctcctttata ttttggtata gcccaattat agcattcttt ttttcttttt acaataatta
    14941 gtatagacca aattgcattt ttttcatttt cttgacaata aataggaatc cgtgttaggt
    15001 ttcataagat ggttcaatca aacaatccat gttgcatgaa aaccaagcaa gtgattcact
    15061 gtggacgctt tatgtctgca gtttttttat gaaaaaggag ttattatgag tatactgaca
    15121 ttaaacaaca ttacccagca atttggcgac aaaatcctct atgaaggtgt cgatctgcaa
    15181 ttaaatgctg gcgaacatct tgggctgatt ggacaaaacg gagccggtaa aagtacattg
    15241 attaaaatca tcactggtga gatcttacca gatgacggac agatccattg gcaaaaaaat
    15301 attcacaaag gttacctcga tcaatatgtg gaagtcgatg aaacattaac aatcgaagaa
    15361 tttctaaaaa ctgcgtacgc aaaagaatac gaaaaggaag aaaaaattgc ttttctttac
    15421 caaacatata gcgagacctt cgatgattcc ttgctggaaa aagctgggaa actccaaacg
    15481 gaattagacc aaggagtgtt ttatcaaatc gacaccttag ttgctgagat gagcagcggg
    15541 ttggggatcg atgtcttagg tttagattca ctgttgaaaa atctaagtgg tggacaacgt
    15601 tcaaaggtga ttttagcaaa actactttta gaaaacccag atgttctgat cttagatgaa
    15661 ccaaccaatc acttagatga tcagcatatc caatggctga cgcagtttct tcaggatttt
    15721 gacggtgcgt atatcgtgat ttcccatgac caagaatttc ttgatcagat caccacccat
    15781 atcgcagaca tcgagtttgg aaagattact aagtatactg gccatctaaa acaagcattg
    15841 aaacaaaagg aacaaaatcg cgaaagctat ttgcgccaat atcatgctca acaaaaacaa
    15901 atcgaaaaga ccgaagctta tattcgaaaa tacaaagccg gttcccgatc aacgatggca
    15961 aaaagccgac aaaaacaatt agataaaatc gaacggctga cgcctccagc ttcagcaagt
    16021 aaagctgtct ttgattttcc attctcgcct attgtcacga cattagcagt ggaaacaact
    16081 gatttagtca tcggatatga tcgaccgcta cttgcaccca tcaatttgac catccgcttt
    16141 ggtgaaaata ttgccattcg aggcttcaac gggattggaa aatctacttt attaaaaaca
    16201 ctgatcggtg agattgaaaa aataagtggc gatttccact tcccagataa cacaaaaatc
    16261 aattactttt cacaagatct gtactgggaa aatccattag aaacaccact acaatattta
    16321 agcagtcaat ttccaaaagc gactatcaaa gaattacgtc gccaactagc taaagcaggg
    16381 ttagttaatc aattagcaag tgaacctctc actacattaa gtggtgggga acaaactaag
    16441 gtgaaacttg cacagttgac aatgaaccaa ggtaatttac tgattctcga tgaaccgacg
    16501 aaccatatcg atcaagaaac gaaagaaagc ttacaagacg ggatacagaa atttccagga
    16561 acagtaatca tcgtctctca tgaacaagaa ttttatcaag atcttgtgca acgagtcatt
    16621 gagattgaac caaaataaac gtttgattga atagttgaaa aaaaggagct gtgacaaaag
    16681 ttttgtcaca actccttctt ctgaataaat ggtggccaat tagctgacct tcggtattag
    16741 ctcaaaaaac ggcaaaatat gaggagctat ttttatttgg ctattcttat tacttgatgc
    16801 agaacagctt ttcacaacct cttttcgtct attttttatt ttcgagattt ctctttcctt
    16861 taaaaacaac tgtttgaaag aagaacgcac atccttgaaa aacaagcccg ctaaccgtta
    16921 cacctaacca gccatactgc tgccacattg tcgtccctag caatgaacca gccgcacctc
    16981 caataaagta cataaacata aataca
//
LOCUS       DAYNVV010000054        16820 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.056, whole genome shotgun sequence.
ACCESSION   DAYNVV010000054 DAYNVV010000000
VERSION     DAYNVV010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16820
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.056"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(18..293)
                     /locus_tag="ACGXWR_002102"
     CDS             complement(18..293)
                     /locus_tag="ACGXWR_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803634.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            587..1402
                     /gene="thiD"
                     /locus_tag="ACGXWR_002103"
     CDS             587..1402
                     /gene="thiD"
                     /locus_tag="ACGXWR_002103"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFK0803635.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKDAQQETVNDYVLLESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(1607..3058)
                     /gene="cls"
                     /locus_tag="ACGXWR_002104"
     CDS             complement(1607..3058)
                     /gene="cls"
                     /locus_tag="ACGXWR_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFK0803636.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQKALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            3399..6065
                     /locus_tag="ACGXWR_002105"
     CDS             3399..6065
                     /locus_tag="ACGXWR_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFK0803637.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNE
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            6429..7181
                     /locus_tag="ACGXWR_002106"
     CDS             6429..7181
                     /locus_tag="ACGXWR_002106"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFK0803638.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(7203..8357)
                     /locus_tag="ACGXWR_002107"
     CDS             complement(7203..8357)
                     /locus_tag="ACGXWR_002107"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HFK0803639.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            8542..10983
                     /locus_tag="ACGXWR_002108"
     CDS             8542..10983
                     /locus_tag="ACGXWR_002108"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HFK0803640.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKPYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     KVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(11313..12017)
                     /locus_tag="ACGXWR_002109"
     CDS             complement(11313..12017)
                     /locus_tag="ACGXWR_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803641.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(12204..12449)
                     /locus_tag="ACGXWR_002110"
     CDS             complement(12204..12449)
                     /locus_tag="ACGXWR_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803642.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(12466..13317)
                     /locus_tag="ACGXWR_002111"
     CDS             complement(12466..13317)
                     /locus_tag="ACGXWR_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFK0803643.1"
                     /translation="MNSLTSTYRLLNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQPTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            13483..14487
                     /locus_tag="ACGXWR_002112"
     CDS             13483..14487
                     /locus_tag="ACGXWR_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HFK0803644.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(14728..15084)
                     /locus_tag="ACGXWR_002113"
     CDS             complement(14728..15084)
                     /locus_tag="ACGXWR_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFK0803645.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            15452..16639
                     /gene="tuf"
                     /locus_tag="ACGXWR_002114"
     CDS             15452..16639
                     /gene="tuf"
                     /locus_tag="ACGXWR_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFK0803646.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
BASE COUNT         5377 a         2973 c         3489 g         4981 t
ORIGIN      
        1 taaagaacag ttagaagtta aaattgctga ttcacataga gtttatgact tcttggaaat
       61 tctttttcaa tcagtttttt catctgttta tgaaattctt ttttttcagt aaacataaag
      121 gtttgggtat cgtaaccttc ttcatgtagg aaatagatta ttcctttttc tgtgttttgc
      181 gtataagctt ttatactcct gtcttttttg aaagaacaga tcgtatagcc atctatttgg
      241 tctggtagtc gtttgatttt cttcaaaatg acttttttat cctcaagttt catttttttc
      301 acctgacttt atttttttca tatggaaatc atagcgcctt tggttatatg aaaacaagaa
      361 ggatactgaa atatatataa atcaaatagt ggttatttat tattagaata gcgaatacaa
      421 acaaatgaca actattttct gatttattac aaatgttttt tcaaataaat ttgattacca
      481 agaaaaggta gtggtatatt tactgaggga tactttgaaa aacatatgat agaaacagta
      541 acagcattat gaaaaatctt tttataaaaa tggaggaatc gatttgatgg aagatcagta
      601 tgtacaagca atgacgatcg caggatcaga tagcgatgga agcgcaggga tgcaagcaga
      661 tatgcataca ttctttacaa gaaatgttta cggtgtttct gtcatgaccg catgtgttgc
      721 aggtaattct tacggaatcg gagcaagtgt gacattgcca acagatttta tcgacaaaga
      781 atttgaactg attgcgaagg actttcaaat acgtgcagct aaaacaggta tgctagcaga
      841 ttcaaagttg attgagacag ttgtaaaaaa ttaccaaaaa tatgattttg gaccattagt
      901 cgtggatccc gtaatcgtaa cgaaacatgg aaatctttta ctagaagaat ctgctttgca
      961 aagcttgaaa gaaaagcttg tccctttggc cgaagtactg acacctaatt tttatgaagc
     1021 agaaaagctg actggacgga cattagcagc tgaagaagat tttgtgcaag cagcaaaaga
     1081 actgcaagat atgggtgcaa aaaacgttat gatcaaagga catcatgcta aagatgcgca
     1141 gcaagaaaca gtcaatgact acgtattgct cgaatcagga aaatcatttt ggttaaatgc
     1201 accattttat cctaccgacc ggatcaacgg aactggcgat tcgctatctg catgtattgc
     1261 agctgagtta gcgaaaggaa aaacagttga acaagcgatc cgattggcaa aagactatgt
     1321 aaaccgtgca attcgtgaag aaataaatgt agggcacaaa tatggaccca tcaatcattg
     1381 ggcagctggt gaattagagt aaaagaaaga ggtcgtgagc ctgccgtcca gctccgagtc
     1441 acaaggaaca agttcaaaaa acagcttctc atgtttgttg aatattgtga cttgtgaccg
     1501 aggagttggc aggagaacac cgtttgttcg gaagaaggga ctgtgacaag atttttgtca
     1561 cagtcccttt aatcttagta tatttttctc tacttgaata aaaaaattat aggattggag
     1621 aaaataatcg agaaatttgt tgcttgaata atagccagtt agacatttcc ttgactgttt
     1681 cagttgtcat ggatgaacaa tgtgtctcat cttctttgaa ctgagtagca agttcttcta
     1741 aaaactcagg atcgtaaatg acagcacttg tttcaaaatt caatcggtag ctacgaatat
     1801 cttgatttgc tgaacctacc atgcagattt catcatccat tatcaatgtt tttgcatgga
     1861 ggaagccgtt ctcatagaca aggatttgta cattttcctt gatcagctgc cgagcataat
     1921 attgtgttgc tcgataaata aaaggatgat ccggtttgtt gggaatcatg attttcacat
     1981 ctacaccaga ggcagttgcg atttttaaag cagcaatgac actttcatca ggaacaaggt
     2041 aaggtgtctg tatccaaaca cgttttttag cagaagtaat caatttgata aatgaaagct
     2101 tgatttgttc cctttcgtta ttcggtccgc ttgaaacaag ctggatggat gtatcagcaa
     2161 gcttagattc atctcgatct gcttttttaa agaaataatt caaatgatag ccgacctttt
     2221 tttcttcagg taccgagacg ttccagtctg ttaagaagcg aagctggagc aaagaagaag
     2281 cggcaccgaa aatccgtata tgcgtatcgc gccaatagcc gaattttttt gttgtattta
     2341 catattgatt ggcaatattg aaaccaccgg tataactaat ctttccatcg atcacaacga
     2401 tttttcggtg atcatggtaa ttcaatcgga aacgaagtaa tgccttttgt gaggtaacaa
     2461 atgtatggac atgtccacca tttttgatta gacgattgaa atcttttgct tttgtaccat
     2521 gagagccaaa tgcatcatat aatattcgaa cttccacgcc ttctgcggct ttttcttcta
     2581 aaacatgtaa gacttgctgg ccgatattat ctgtcacaaa tgcgtaatat tcgatatgga
     2641 tcgaatgttt ggcttttttt agatcttgaa gcagtgaatc caatttctct tgtccgtctg
     2701 tgagaagagt gacagaattc attcttgtca gcggcatacg atttaatgaa gagaagaagt
     2761 cgacaaattg ctgtttgtct ttatcgccca tgtcaggatc gtaatgttca atggtatctc
     2821 ctctaaaaga ctgaaagttt tctaattctt tcaagtcact ttgtcggaga tagaattttt
     2881 tcttatccgt taatccacgt ccgaaaaata aatataatac aaagcccacc ccaggaaggg
     2941 caaacaatac taagagccat gcccaaatgg ctgctacatc tcggggtttg atcaaaatag
     3001 ccaccaaagc aataagtgca tttaatagat aaagggcggt tataatacta gataccacaa
     3061 aaatgttcct ccttacatac aataacatta gtatagcatg atagaagaaa gaagcctacc
     3121 aaggtgaata tacttttcac tcctttcatg aaaatgtagg taaatcgggc taaagtagtt
     3181 gctttttgta ggttaataag gtaggatatt agtacagttg aatatctcct taggggagta
     3241 accggcaacg tttgttgcga taatatcaac agtaagttaa ccaaatggtt ttctggtatt
     3301 gtatgaaatg gtgagaccta agacaaatgc gtatttgtct taggtctctt ttttttcaga
     3361 caggactagg gccaagatca aaaaatgggg gatgaaattt ggaaaacaag gaacaagcac
     3421 aacaagcggt ctataaagaa acgatcgact cgttgatgca gcaaacgcag agctcaaccg
     3481 atggattgag caccacgcaa gcgaaggaaa aattagaaag agatggcttg aaccagctaa
     3541 aagaaaagcc gaagaagcca acttggaaat tgttcttaga aactttcaaa gatgcaatgg
     3601 ttatcgtatt gctgattgtc gcactgattc agatggtcat gggtgactac atcgaattct
     3661 tagttatttt tgcagtattg atgttgaatt ctataatcag tgttgtccaa acaaaaaaag
     3721 cagaaggttc tttagaagcg ttgaaaaacc tttcagcgcc cgatgctcga gtgattcgtg
     3781 atggtaagga aaaaacgatt ccggcaaacg aacttgtggt aggagatatc gtgttgttag
     3841 acgcaggcga ttatgtacct gctgatggac gtttactaga tgcgggatca ttaaaagtag
     3901 atgaaggtat gctgacagga gagtcgactt ctgcagaaaa agaagtaacg gatatcacaa
     3961 gtacggtacc aatcggagat cgtacaaata tggtattcag tggaacgatc gtaacttacg
     4021 gacgcggtaa attcttagtg acttcaactg ggaataatac ggagatcgga caagttgctg
     4081 gccttttgga atcaacaact gagcaagtca ctccgttaca acgaggtctg gataaattca
     4141 gtaaaaaact aagtctggct attttggcat tgtctttatt gattttaggt atccaactgt
     4201 ttcgtattta tcttggagaa ggtacaggag atatgactgc agatatcgtc agcgcagtga
     4261 tgtttgccgt agccgtagcc gtagctgcta ttccagaagc attacagtct atcgtaacaa
     4321 tcgtgttatc tttgggaacg aataaaatgg caaaacgtca tgccattatt cggaagcttc
     4381 cagcagttga aacacttggt tcgacaagta tcatctgtac agataagact ggtacattga
     4441 cacaaaacaa aatgacagtt gttgactact ttttaggtaa tggcgatact ggggatttca
     4501 caaatgaccc ttcaaaatgg acagctgacg aacgtcgctt gatcgaaatc agtgttttag
     4561 cgaatgatgc atcgatcagt gaagacggta ctaaattggg cgaccctacg gaagtagcgt
     4621 ttatcgactt tagtgaaaaa ttaaaccagc cttatcagga aatccgaaac aactacccaa
     4681 gacaagcaga acttcctttc gattctgatc gaaaattaat gtctactgga cacacgatcg
     4741 ataacgaaaa ttacttgttt gtcaaaggcg gaccagatat cgtcttccaa cgcagtaaaa
     4801 aagtattgct aaatggtgaa gtcgttccga tgacggatga attgatgaaa aaattccaag
     4861 agcaaaatga agctttttca acacgcgcat tacgtgtact agcttttgct taccgtccac
     4921 ttgataattt tgatttatca tttgaagatg aagacgattt gatccttgtt ggtttgcttg
     4981 ctatgatcga tcctccacgt gctgaagtga ctcaggcggt aacagaagca agaagtgcag
     5041 gaatcaaaac aatcatgatt actggtgacc acaaaacaac agctgttgct atcgcaaaac
     5101 aaatcgggat ttttgaagaa ggaaacctgg ctttgaccgg gacggaacta gatgaattga
     5161 cagaagatca actaaacgaa gttttagaaa aagtcactgt ttatgcacgt gtttcacctg
     5221 agaataaaat tcgtatcgtt cgtgcttggc aaaataaagg tcatatctca gctatgacag
     5281 gtgatggtgt aaatgacgca ccagcattga aacaagcaga catcggaatt gctatgggaa
     5341 cgggtacaga tgtggcaaaa gatgcagcag cgatggtatt gacggatgat aactttgctt
     5401 ctattgtcag cgcagtagaa gtaggacgta atgtgtttga taatatcaag aaagctattt
     5461 cttatctatt tgcaggaaat ttaggtgcga tcattgcgat catctttgcc ttagttgctg
     5521 actggtccaa tccatttaca gcattacaac tgttgttcat caatttagtc aatgattcac
     5581 tgccagcaat tgcattaggt acagaaaaag ctgaacctgc tacgatgaac cgcccgccaa
     5641 gagatccaaa ttcaggaatc tttacggaca aaacattgat ttctgtaacg tatcgtggtg
     5701 tgctgattgg gattgctgtt atctttgctc aatggcttgg catgcagcat tcacctgaat
     5761 tcggtgtagc catgtcattt tcaacattga tttggtgtcg gacattgcaa acattcccag
     5821 cacgttcaaa cacacaaaca gctatccaag cagggttctt ctctaacaga agtgtcttac
     5881 tagctgtagt tgtatgtagc gcgctttact gcttaacaat gatcccagga ctgaaagaag
     5941 tcttctctat cccatcagca tttggattga cagaagtctt tacatgtatg ggaatcgcac
     6001 ttgtgacaat tgttttgatg gaaatcacta aattgatcat tgtacgagta caaggaaata
     6061 aataaaacga atcaacgagg ttgtgagcct gccgtttaat tctgagtcac aaggtgcaat
     6121 ttcaacaaac agcttctcat gtttgttgaa tattgtgact tgtgaccgaa gagttggcag
     6181 gagaacaccg tttaaggaag aagttgtaaa atcagcattt tgagctaata ctgagggtca
     6241 tctgattgga cactgtttat tcggaaagag ggactttgac acgactttgg tcacagtccc
     6301 tttttttatt tatgatagac ggaaagccaa tcattttatt attcatcaaa agagatagaa
     6361 tagataaaag aggagaataa tttattccga aaagtgaaaa catataacaa aaaattagag
     6421 gaaatcaaat gaatgaaaaa gaatgggatg aatttgctga agaatattat gaaatccagc
     6481 aagaatcgca agtaactatt gctgaagatg taaaaaatta tctgaaaacg gagaaagtcc
     6541 tgcctgctga aacagcagca gacgttgctg gaggatctgg cagatttctt tccttagcaa
     6601 aagaaattaa tcgctatgat ttgatcgatt tttcttcagg aatgctagaa aatgcaaaaa
     6661 aagaagcaga aaaaaatgag ttgccaaatg tttcctttat caaacagtcg ttagaagaat
     6721 ttatccaatc aaatgagaca tatgaaatgg tttttacagc agcaaatcca gcattggtac
     6781 atcttattca attagaaaaa ttgatgaaaa agtcaagcaa atggtgcgtg ataatcaggg
     6841 tagtggaatc aatcgatgat gttttttatc ctatcgaaaa gcaactagga atgatagaag
     6901 aagatcctaa tacatcgcca gttgtaatgg atcaatttga aacatactta attgatgaag
     6961 gattcaaagt gaagaaaaaa gattttactt attttacaca ggaatcaatt actgaagaat
     7021 tgatgaagct atactatgac gcgtacgcaa aagatcctgt tgtgaccagg tacattcgca
     7081 aactattcag tgaaaaacga gaaatcctta gtacgactaa gctgacctat agactgctcc
     7141 tttggtccgc agataaaaaa agaacctttc acgactcgtg aagggttctt tttatgattt
     7201 tattatattt tgtagtaacg aatatcattt tcgatctttg taatcgaaaa aggtacatct
     7261 gaagtatatt ctgcacattc tccgtgttca ggaagcgtct cactgaaaat cgtttcatat
     7321 tcgtcaacag tgatccgtgt tcgagaatct agcatctctt gatgagattg tgcgaagaga
     7381 tattcttgat agttttcttc cagataacct gtaaaaaatt cacttactgc accagaaccg
     7441 tagctgaata gaccgatgcg atctcctggc tgtagtgatt tcgaattttc cagtagagaa
     7501 gttagcccca ggtataatga accagtgtaa agattaccga ttcgtcggct gtaacggatg
     7561 ctttcttcat agcgagccat aagacgttcc tgattttctt cgtctgtttg gtctaatacg
     7621 ctttgcaatg ccttttttcc catcttagta tacggaatat ggaaagcaat cgcctgataa
     7681 tcttcgagtc ctcgacccga caattcttta tgtcgattcc aaactttttg gaatgattcg
     7741 atatacgtag aattagataa aggaccatca acaacaggaa attcgctata atctggacgc
     7801 cagaaatcat agatatcttc tgtcagaaat acgctgtcgt cttcaatcga taaaatacgc
     7861 gggttttgag tgatcatcat cgcaacagca ccgacacctt gcgtcacttc accaccgctt
     7921 gccaagccgt aacgagcaat atcacttgct atgactagta cttttcgttc tggatgattt
     7981 ttgacatatt ctttcgccat gtgcaaagct gcggtgccac cgtagcaagc ctcttttact
     8041 tcaaaagaac gagcaaaaga ttggattttc agtaaatggt ggataattac cgcactcgct
     8101 tttgaatgat caatcccgga ttctgttccg acgatgacca tgtcgattag ctcacggtct
     8161 ttttctgtta cgattttgct ggcagcattt gctcctagtg taatgatgtc ttcatttgca
     8221 cgattgactg ccatttggtc ttgaccaatc cctatatggt attttgcagg atcatcccca
     8281 cggctttctg ccaactctgt catatctaaa tataaattag gaataaaaaa ggaaagacga
     8341 tcaatcccta ttttcatttc aacacctctt tacttatgat aaaaaactta ctttactaag
     8401 gtatcataaa aagattaaaa gaaatataaa aaagagaata tttaaggatt gttaaaattt
     8461 aatcttagaa aaaaacaact ggaacaagag ctatttgttt ttacagcaaa gaatggtata
     8521 tttttgtagg aggtggctta cttgaaagaa gtcgttatga tagatgctgc aagaacgccg
     8581 ataggaaagt atcgcggaag tttaagtcca tttactgcag ttgaattagg cacacttgtg
     8641 actaaaggat tattagataa aacaaaactg aaaaaagata aaatcgatca agtaatattc
     8701 ggaaatgtcc tgcaagctgg taatggtcaa aatgttgcca gacagattgc tttgaacagc
     8761 ggtctccctg tagatgtccc agcaatgacg atcaatgaag tttgcggatc tggtatgaaa
     8821 gcagtgatct tagcacgcca gctgatccaa ttaggtgaag cagaacttgt gatagccggc
     8881 ggaacagaga gtatgtctca agcacctatg ctgaaaccgt atcagtcaga aacaaatgaa
     8941 tatggtgaac caatttccag tatggtcaac gacggattga ctgacgcatt ttcaaatgca
     9001 catatgggat taaccgcaga gaaggttgca acacaatttt ctgtgagcag agaagaacag
     9061 gatcgctatg ccttgtcgtc ccagttgaaa gcagcacatg ctgtcgaagc cggtgtattt
     9121 tctgaggaga tcatcccagt caagatttct gatgaagacg tgttatctga ggatgaagca
     9181 gttcgtggaa atagtacatt ggaaaaactg ggcacgttac gtacagtatt ctcagaagaa
     9241 ggaactgtaa cagcaggaaa tgcttcgcca ttgaatgacg gtgcctctgt ggtgatcctt
     9301 gcatccaaag aatacgcaga aaataataat ctgccttatt tagcaaccat caaagaagta
     9361 gcggaggtcg gtattgaccc aagtatcatg ggaatcgctc caatcaaagc cattcaaaaa
     9421 ttgacagata gatcaggaat gaatttatca acaatcgatc tttttgagat caatgaagca
     9481 tttgcagctt cttctatcgt agttagccaa gaactgcagt tagatgaaga aaaggtcaat
     9541 atatatggag gagcaatcgc attaggccat ccaattggtg caagcggtgc acgtatcttg
     9601 actacattag cttacggatt gcttcgtgaa cagaagagat acggtattgc ttcattatgt
     9661 attggtggag gtttaggctt ggcagtcttg ttagaagcga atatggagca aacacataag
     9721 gatgtgcaaa aaaaaaagtt ttatcagctt acgccatctg aacggcgcag tcaattaata
     9781 gaaaaaaatg tattgacaca agaaactgcg ttgatttttc aggaacaaac actttctgaa
     9841 gagctctccg atcacatgat cgaaaaccaa gtgagtgaag tggaaatccc aatgggcatc
     9901 gcgcagaatt ttcaaatcaa tggtaagaaa aaatggattc cgatggcaac agaggaacca
     9961 tctgtcattg cagctgcaag taatggtgca aaaatctgtg gaaatatctg cgcagaaaca
    10021 cctcagcggc tgatgcgagg gcaaatcgtt ctatcaggaa aatcggagta tcaagcagtg
    10081 atcaatgcag ttaatcatcg aaaagaagag ctgattcttt gtgcaaatga aagttatcct
    10141 tcaatcgtga aacgcggggg cggtgttcaa gatatctcta ctcgggaatt catggggagt
    10201 ttccatgcat acttatctat tgatttttta gtggatgtaa aagatgcaat gggcgctaac
    10261 atgatcaact cgattcttga gagtgtggca aacaagttac gggagtggtt ccctgaagaa
    10321 gagattctat tcagtatttt aagtaatttt gctacagaat cattggcttc tgcctgttgt
    10381 gaaatcccat tcgaacgctt agggagaaac aaagaaatcg gtgaacaaat tgccaaaaaa
    10441 atccaacagg caggggaata tgcgaagctt gacccttacc gtgcagcaac gcacaacaaa
    10501 gggatcatga atggtataga agctgtagtg gcagctacag gaaatgatac acgtgcggtt
    10561 agcgcttcga ttcacgccta cgcggcaaga aatggattat accaaggatt aacagactgg
    10621 cagatcaaag gggataaact agttggaaaa ctaacggtgc ctttggctgt tgccacagta
    10681 ggcggagctt ccaatatcct gccaaaagca aaagcatctt tagctatgtt agatattgat
    10741 tcagccaagg aactagcaca agtaattgct gcagtagggt tagctcaaaa cctggctgct
    10801 ttgcgtgcat tagttacaga aggaatccaa aaaggccaca tgggacttca agctcgttca
    10861 ttagcgatct caattggggc tattggtgag gaaatcgagc aagttgcgaa aaaattacgt
    10921 gaagcagaaa agatgaacca gcagacagct atacaaatat tggaaaaaat ccgggaaaaa
    10981 taaaaaagca atatctttag aagaataaag caagatttac agttatttta tttactgcaa
    11041 atcttgcttt tttctctatc agaaaatatg tttattatta gaatttttta tagttaaggt
    11101 taggcatctt aagaaatcag gcaactccaa gatatcttca ggtagaagag aagtcgccta
    11161 acattgtagg atcataggtg atttgttgga caggtcaagc tgatatttga gcctgatgtt
    11221 agaaggaatt tctttttact tgctgtagaa attattatat gactaaaaag gctgggattt
    11281 taaatcccag ccttttatga caaatagaat ttttatcgat cagtaatcgc tgtcgctgca
    11341 aattgttcga tcaaaggaat caaagtcaat ttgactttgt atttccgttc gagtgctttt
    11401 tcgataacga actcattttc agtagtcata gaaatagttg ctaatttacg aggttcatca
    11461 gcattttttt cattaataac tacttcatgt tcattttgtt ctgtgtaaaa tttaggatac
    11521 tcagcaacgg cttttgaaaa atcagcaaaa cttaaagcgg cattcgtatc agttgagcgt
    11581 gtattttcag ttgtgtccgc ttttggtttt tccgtttttt cttctggcac actgactgtt
    11641 tcttctgtaa ctggtgtcgc aacagcttgc gcagttggtt catcgttttt caatcgttga
    11701 tcattccagt aagacacgat ttcaataaga agattgtcac ggaatcgttc gaaaatcccg
    11761 ttttctcctg aacgaattct ctttaataca gtattgaagt tgtcatcgat tggcacgttg
    11821 atccgtgtat cttcatttgt tttcccagct aatccgatcg ttaagatttg acggtttttg
    11881 ggatcaagca tgacttgtaa cggcaaacca tagcgtcgca agctctcttc ttctagagaa
    11941 cggaataatt gtcctcttac accatccaat gaaggacgga attgatttaa taatttttgt
    12001 ttctgttttt tcttcatatg ttctctcctt cgctcatacc ctttcgatta taagaaaaaa
    12061 acagccaaat gaaaaggagt aatgcaaaaa aacttgcgta tacgcaaatt acaacagaaa
    12121 aatttgcgta ttttcccgtt ttttgaaaga aaaataaaaa atggaacgga ttatgtatat
    12181 atacataatc cgttccattc tttctatttt ttcggtatca aggcaaaaac aggtagttca
    12241 ggtgaataaa tgacttcatg ttcgtgccag ggtttgacca ttagcgaatg atcgaaccgt
    12301 tttttcagtt cttcgatgat ttgatcatgt gtccagtttc ttgcaggaaa atgttggatt
    12361 ttctctgcat cgatcaaaaa gacaaaatcg gaatgaaaag tctgggtaac ttcttccgag
    12421 agagaattca agcgttcgat tggatccata aaatcacctt tcgacttaaa attgggtagt
    12481 atctgggtct tttgctttgc cgactacacc atctaactga tcgatttgtt tcatttcttc
    12541 ttctgttaat tcaaaatcaa ataattcagt attttctttg attctgcttg gtgtcactga
    12601 cttaggaaga ggaaggaatt cgtgttgcag cgaccaacgc aaagcaactt gtgcaatcgt
    12661 cttgtcatgt gcttcagcga tttgtttcat ttcaggcaca tcgaagattt taccagtgcc
    12721 taatggacta tatgcttcga ggatcatatc atgttttttt gcatactcaa ctacagttgg
    12781 ctgtaattcg cctggtgcaa ggaaaacttg attgaccatc ggcataattt ttgctgtttt
    12841 tgctagtgta tctagatggt ggggtaagaa attgctcaca ccgattgctt tgattttacc
    12901 tgcttcatac agttcttcaa atgctcgcca tgtatctgca tttgcttgtt cccaattatc
    12961 acgaaaagca acagggtttg gccagtggat caaaaacaga tctaaataat ctgtttggag
    13021 cttcttcaat gattcttcaa aagaagacat cacaagttca tagctgtggt ttgcattcca
    13081 taattttgtt gtcaagaata tctcttctct aggaattcca ctttccttaa tcgcttggcc
    13141 gacactttct tcattcttgt atccttgggc agtatcgata tggcgataac ctgcagccag
    13201 cgcttcttta acagaggaaa cagcgacatc cccatcaggt gtttgccatg tgccgaatcc
    13261 tactaccggg atttcgtaac catttaatag acgataagtg cttgttaatg aattcatact
    13321 ttcagctcct tttttattcg ttcaactata agtgtagcgc atttttcgaa aaaaagaatc
    13381 cattttgttt ctactcttga aatttttgtt taaaagaaaa tgattttgat tctggtattt
    13441 ttgatttttt ttccgtaaac taagacagaa gggaatgaga aaatggatat ctatttaaaa
    13501 aaagcaattc tgcatattat tgacagagaa actggttctc cagtcttttc acaaaaagag
    13561 ctggatctga caaaagaata tattcgtgat tttcttcaaa agaagatcca aaaaatctct
    13621 tctgctcaaa caaaaactgg acaactagca gaagaaagca tgatcgttga atcacttaaa
    13681 atcgctcaag aaaattttgt ggaagcaagt gaagcaatcg ttcagcggtg gttcgatatc
    13741 taccaagaaa gtgaagaagc acctagtgca gatgtatttg ttgttttgta tgaattagat
    13801 acagtgatgt acttatcttt attgaaagtc aattatcgtg aggcttacac tcactttgtt
    13861 gaagcagacg aagcagggat cgacaaccgc ttgattttga atcgagcaat tctaggggcg
    13921 aaaacacaaa aagcagatga agcattcgct gtgaatttga ctgattggac ctacgaatta
    13981 attgaaaaaa aatatgagtt ttctggcaaa aaagagcttt atttttctgg aagagtgatc
    14041 gaaagtgttc ctgcaccttc tttagaagaa aatgtaaaag tgatccaaaa agtagccaag
    14101 catcttggaa aaaaatttga gacagaagaa tttgatatca tggctgattt gaaagaagct
    14161 gtctatgata cgatagaaga aaaaggtcgg ttggatcatg agatgattgc ggaaaaagtc
    14221 ttcaaggaaa acatcacggc aaaaatggct tttaaagaag aagtacaaga gcaaggattt
    14281 gtcccagaag cacctcctgt aaaagaagta caagaaattt ctgagaaaaa atttggaaaa
    14341 caaaaattca agctatcaaa cgggatcgaa ctgatcgtac cagtagatgt atatcgcaac
    14401 ccagatttga ttgaatttgt gaataatccg gatggtacga tatccgtgat gatcaaaaat
    14461 gtggatgaag tattgaatcg tttataaaaa tgactagaac attaggtgtt caagtaccag
    14521 tgatcagtta aatgaattgt gtcaagagaa ggatcggaaa agacgaatat aacaaaaaaa
    14581 gagcgtgaga caaaagtaaa gaacactttt gtctcacgct ctaaacacgt ataaacggcg
    14641 gaagcagaag caactccttc ttatttcttg gagttaaacg cttctgtccc agcctctttt
    14701 tatctaataa aattttaaga ccatttacta attatcgatt ttttctgccg catttttagg
    14761 cacttcagaa gcctttattt cttcccagct taatacacct ttacgaggat tgactttgag
    14821 tttaagatac gcattcatct ttaatggatg ttctctttct tcgcgaagcg tcacctgttt
    14881 tttttcacca tctttattat aagccgcttg cttgtaggta taagtcgtga atttctctcc
    14941 gttatctgct tgggtagctg acatttcgcc attcgtcgtg atttttgtat aataagcttc
    15001 gccgccgtaa aaataatgat aagctgcaaa acttccgccg agaaatatgc ctaaaacgac
    15061 aagtacgcca attaattttt tcatgtactt cacctctttc cttattatta acgaaataga
    15121 agatttcgtc tattgaaagt tgttggcaac agctgaattt taaacttttc ctcattttgt
    15181 tcttattgct tcaaaagaaa gttaaggact atcttgaagt ttttctcaaa aaacacattt
    15241 ttttatttat aaaaggtact tttttcgcgt ataagacaag cgagtgctct tagttgactt
    15301 tgaccaatat tgacgtataa taagcttagt tcgaatctta caaaaagtaa gtcggacgta
    15361 ttctttttga tttagtcaaa aaaagactat aataaaaagg tgagagctga aatttttcag
    15421 tgatctatat tatttaggag gtttgtaaat tatggcaaaa gaacattatg acagaagtaa
    15481 accacacgtt aacattggta cgattggaca cgttgaccat gggaaaacta ctttaactgc
    15541 tgcgatcact acagtattag gcaaaaaagg cctagcaaat cctcaagact atgctagtat
    15601 tgatgcagct ccagaagaac gtgaacgtgg gattacgatc aataccgcac acgtagaata
    15661 tgaaacagaa aaacgccact acgcgcatat tgatgcacca ggacacgcgg actatgtgaa
    15721 aaacatgatt acaggggcag cacaaatgga tggtgcaatc ttagttgttt ctgcaactga
    15781 cggtccgatg cctcaaacac gtgaacacat tttattgtca cgccaagttg gtgtaaaata
    15841 cctgattgtt ttcttgaaca aagttgattt agtcgatgat gaagaattga tcgatttggt
    15901 agaaatggaa gttcgcgagt tattgagcga atatggtttc ccaggcgatg acactcctgt
    15961 gatcaaaggt tccgcattaa aagcattgca aggcgatcca gatgctgaag ctgctattat
    16021 ggaattgatg gatacagtag atgaatatat cccaacacca gaacgtgata cagataaacc
    16081 attactattg ccagtggaag acgtcttctc aattacaggt cgaggaactg ttgcctcagg
    16141 tcgtattgat cgtggtgctg ttcgtgtcgg tgatgaggta gagatcgtag ggatcaaacc
    16201 tgaaacacaa aaagcagttg taacaggtgt agaaatgttc cgtaaaacgt tagattacgg
    16261 ggaagctggg gataacgtag gcgtgttgtt acgggggatc caacgtgacg atatcgaacg
    16321 tggacaagtg cttgctaaac caggttccat tactccacat acaaaattca aagcagaagt
    16381 gtacgtgttg acaaaagaag aaggtggacg tcatactcca ttcttcaaca actatcgtcc
    16441 acaattctac ttccgcacaa ctgatgttac aggaacaatc acattgccag aagatacaga
    16501 aatggtcatg cctggtgaca acgtgacgat tgatgttgac ttgatccatc caatcgctgt
    16561 tgaaaacgga acgacattct caattcgtga aggcggacgg acagtgggtt caggtatcgt
    16621 tacagagatc gaagcataag aaacgcgact cgaatatttt ggtaatgaaa aatgtttaaa
    16681 ataaaagagc ggtccaaaca ggatttctgt ttggaccgct ctttgttctt caattgtata
    16741 agaagagatt gtagaagcat gaactttcgt tttacttcag tctcttttat tcatcatgag
    16801 agtgttcatc tatcggtatg
//
LOCUS       DAYNVV010000055        16615 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.058, whole genome shotgun sequence.
ACCESSION   DAYNVV010000055 DAYNVV010000000
VERSION     DAYNVV010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.058"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..525
                     /gene="scm"
                     /locus_tag="ACGXWR_002115"
     CDS             <1..525
                     /gene="scm"
                     /locus_tag="ACGXWR_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFK0803647.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSD
                     TRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVI
                     GLRITFMSYKKSKR"
     gene            complement(680..1666)
                     /locus_tag="ACGXWR_002116"
     CDS             complement(680..1666)
                     /locus_tag="ACGXWR_002116"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFK0803648.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1689..2255)
                     /locus_tag="ACGXWR_002117"
     CDS             complement(1689..2255)
                     /locus_tag="ACGXWR_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HFK0803649.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2269..2685)
                     /locus_tag="ACGXWR_002118"
     CDS             complement(2269..2685)
                     /locus_tag="ACGXWR_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HFK0803650.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3142..5076)
                     /locus_tag="ACGXWR_002119"
     CDS             complement(3142..5076)
                     /locus_tag="ACGXWR_002119"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFK0803651.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5378..6313
                     /gene="pplA"
                     /locus_tag="ACGXWR_002120"
     CDS             5378..6313
                     /gene="pplA"
                     /locus_tag="ACGXWR_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular electron transfer flavoprotein
                     PplA"
                     /protein_id="HFK0803652.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6403..7506
                     /locus_tag="ACGXWR_002121"
     CDS             6403..7506
                     /locus_tag="ACGXWR_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFK0803653.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7519..8472
                     /gene="menA"
                     /locus_tag="ACGXWR_002122"
     CDS             7519..8472
                     /gene="menA"
                     /locus_tag="ACGXWR_002122"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HFK0803654.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9407..10753)
                     /gene="gor"
                     /locus_tag="ACGXWR_002123"
     CDS             complement(9407..10753)
                     /gene="gor"
                     /locus_tag="ACGXWR_002123"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HFK0803655.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10887..12140)
                     /locus_tag="ACGXWR_002124"
     CDS             complement(10887..12140)
                     /locus_tag="ACGXWR_002124"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HFK0803656.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(12146..13069)
                     /locus_tag="ACGXWR_002125"
     CDS             complement(12146..13069)
                     /locus_tag="ACGXWR_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HFK0803657.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13290..15782)
                     /locus_tag="ACGXWR_002126"
     CDS             complement(13290..15782)
                     /locus_tag="ACGXWR_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HFK0803658.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15789..16256)
                     /locus_tag="ACGXWR_002127"
     CDS             complement(15789..16256)
                     /locus_tag="ACGXWR_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HFK0803659.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(16392..16465)
                     /locus_tag="ACGXWR_002128"
     tRNA            complement(16392..16465)
                     /locus_tag="ACGXWR_002128"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16429..16431),aa:Arg,seq:acg)
     gene            complement(16523..16596)
                     /locus_tag="ACGXWR_002129"
     tRNA            complement(16523..16596)
                     /locus_tag="ACGXWR_002129"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16560..16562),aa:Pro,seq:tgg)
BASE COUNT         4907 a         3475 c         2958 g         5275 t
ORIGIN      
        1 acatcagctt caagtgacag tacagatact acctctacca caagtgatag cacggacacg
       61 tcagcttcaa gcgacagtac ggatacatct accacaacaa gtgatagcac ggacacgtca
      121 gcttcaagtg acagtacaga tactacctct accacaagtg atagctcaga ttcatctacc
      181 actacaagtg atagcacgga cacgtcagct tcaagtgaca gtacagatac atcctctacc
      241 acaagtgata gctcagattc atcaacttca agcgatagta cagacacgtc gtctaccaca
      301 agcgatacac gtcatgcaag tgtctccttc tcaaaaacaa gttcggataa caggacgaac
      361 tttaacttaa ctaataaaac aagcaatgac aatggaaaca aatcaaaaag agcacttcct
      421 aaaactggaa gtcaatcgaa taattggata acactcgcag gcgttatatt acttgtaatc
      481 ggtttaagaa tcacttttat gagttataag aaatcgaaaa ggtaaaaaaa tattcaagat
      541 aaaaaagagc aacgtcgcta acggacgttg ctctttattt ttgcttttta tcataaatac
      601 aagaactaca attcaatttg tcaaaaaaca cgtagatttc cttctgagaa atttatttac
      661 gtatcgaacc tttccctatt cagtctttgc gatccaaaat cagttgggta agggaaaaga
      721 gattctcttt tgttcgaaga gaggtggcag gtaatttctt tatttccttc aaagcctttt
      781 ctgtgtaaga ggccgctaac ttcctagctt cttccacgcc tcctgtatgt tcaacgattt
      841 tgcgtacggc gtcgacatct tcttctgtca ttgccgcttt cttctctaaa taaggtagta
      901 gctttggttt gtttttttgc aaagagtaga tcaacggtaa agaatagacc ccttgacgca
      961 tgtcttctag tacaggtttg ccgatttcct ggctctcttt tgtataatct aaaatatcat
     1021 cgataatctg aaaggccatc ccgatagaaa gtccgatatc tcctgctttt tttgcgaagc
     1081 gctcgcttgt tccactttca aaagcgccaa cagaacaact taattggaac agttcagctg
     1141 tcttacctga aatattttcc aaatattctt ttacagaaag ttcataatta tagcgatcat
     1201 ccatctgccc taattcgcca ttcaatactt tttccatact gcgagaattc aattggagac
     1261 ttttcaagga agtggagtaa tcagacaata gtttaaaaca gcagacaaat aaatagtctc
     1321 ctgcatagac agaaacgaca ttaccaaact gactacggat attaggctga ccacgtcgca
     1381 gatccgcttc atcaacgata tcatcatgga tcagtgtggc cgtatggagc atttcgatag
     1441 aagctgccaa agcgatggct ttgtctcgat cttgctctgg tccaaattgt gagaacaata
     1501 gctgataggc aggacgcaac agctttccgc cggcatggat cgtttctttg atggcttgtt
     1561 cgacaggttt gtttttcagg cggacagttt cttccatccg ttttagtgtt tctgtcaatt
     1621 ctttacttaa agcaggatag ttttcccaca ttggatgtag cttcataaaa aaactccttg
     1681 tgtgacgatt attttttggt aaacattggg ctccattttt gtttggttcc ctgctcataa
     1741 tctttttgga atcgttgaag tgtctgcaca tgtcgtaaaa gataattcgc tgcgatcccg
     1801 attgcaatcc ctgataaaat ccctaaaact gaaaggactg gcaagtacaa catgactgtc
     1861 catgattgtg caatgaaaga agccatcaaa agctgtccga cattatgcat gaaaccgccg
     1921 gccgcactaa ttccgatgat actgacacgt tttggtccta attgcttgac caataacatt
     1981 ccaaaataac taagcaaagc accactcata ctataaagga atgtggaaat cgttccgcct
     2041 agcaaagtag tcaggaatag tcgtagccaa agtagtaaga agctgtcttg ttttttcatg
     2101 gtaaaaatgg caacgatcgt gattagattg gctaagccta gttttgcacc aggcgcaaaa
     2161 gaaaaaggat aagggatcat attttccaat aaaccaatga tcactccttg tgcaacaagt
     2221 agcgaaatat aaatcatttt ttgtaattta ctcatggtgt gtgaaggtct aataaatcag
     2281 actgtcttcg tcacctccat ctgttgaacg gacttcgatc actaatttat gtggcaaaca
     2341 gacgatggtt tcgccatttt tcgttgccca gcctcgacgt acgcagatct ggtcatcgca
     2401 atctgcttct tttatccgta ctcgatcgcc atctatctcg atcaagttat aatctccgtg
     2461 ttcatctttg taagtatatg tgttgctctc ttctccagcc atcaaaggga atgttttgat
     2521 ttctgtgcca tccacacgca gtaccgcttc tttttctgct gttgcggtgt tttgctgaag
     2581 accaaaaatc atgactggta aaaaagaaag aacagtcaaa agcaaaataa taaaaacatc
     2641 ccaaggtttg agcagacttt tttcagcaaa ttctttaagg ctcatttttg ttctcctttt
     2701 tccagattaa ctcacccaat tttagcataa aaacaagagg ttgtgacacc tgtgtcttgc
     2761 tttgagtaat aagaacgaag aatagaaaac agctttccat gttttctaat tctttgggct
     2821 tattaccgag aagcagcagg tggaacaccg tttataacaa gaggttgtga cagaagtggg
     2881 caacttcaag aaataagaag gaatttacga aaattacttt tcaagttttt gtgaaatttc
     2941 ggcttatttt tcgaagaagc tacttctgga acaccgttta taacaagagg ttgtaacaga
     3001 ggttgtgaca cctgtgtctt gctcatggag gcttatctcg ggcatcttat tcctttaatt
     3061 ttacataaaa aggaggctgt gacggtttgt ctcagcccct ttctattgaa atcttgcatt
     3121 caaataacgt tctttatcta tttatttctt gccgtactgg gaacttggtc taccgtacca
     3181 ccaattacct agtgtacgtt gtagccatgg aattacccag cgatccaacc caatcgcacg
     3241 tccggaaccg ttcatcaatg cgaaagcaac aaaaatgaac caaatgttta cccagtaaaa
     3301 catgcctgat aagcagaacg tgatcaccaa tacaatcgtt gtcgcactgc atagccatgt
     3361 gaataatcca gcaatcaatg ctaatgccaa ggcaatttca aagaatacca tgaatttttg
     3421 gaagaacatt gctacatcat tgtttggcat gatcacttgc atgatctttg tgaaccagtc
     3481 tggtgacttc tcaatcacag ccattggttc ttcaccgtat gcataactca aaccaaaatg
     3541 tgcagcttga gtcgctgctt ctccggcact tgcccctgct ccgctggcag ctgtggttgc
     3601 atcaccagca gcagaagcac cactggcaac atctgttaca ttgtattccc atgtccaagg
     3661 gaacacactg tttccagtga accatgatcc ttcaccaaac caagtacttg gtttgaacac
     3721 ttcaccattc ccaatgattt ttttggaagc ttcaacgaac caaactaaac catagaaaat
     3781 acgaagtggc acactccata agacattgcc gtaacgagaa gaatgtcctc gagtcacgtt
     3841 gcgatcatct ttgatatgga aaaactcatg cattaaatat tggaacatat aataaccaga
     3901 acgaatatca aagaagtatt tcaaattcac gatatgtttc attacgatag ctaaaaatcc
     3961 gcttaaatgg atcttatcaa ataggttagc taccccccat ttggcaccaa tagaaaccat
     4021 aaatccttga tagtttcctt taaatttatg cttttctccg cctttgatcg aagccacgat
     4081 attcgctgcg gctgtgtgtc ctgtttgttc agcagcttga acgatctgcg gtgtcggtgt
     4141 tcctgggaat tcttcataaa agactaaatc accaatgata tagatgtttt tatcttcgta
     4201 gccttttgcc tgcatatatt cattggcgat caaccgctgt ccgcgtgctg attctaatcc
     4261 aaagtcagca gcgtcagaag ttcctttgac accagctgtc caaatcagtg tgtgagtcgg
     4321 aatgttgcgt ccgtctttca atttgatatg atcagcagcc acttctacga ttggtgcatt
     4381 caataataat tccacgttgt gcttacgcaa atagcgttca gcttttgcag catcatttcg
     4441 atccaacata ttcaagatcg tcggcattgc ctctacgacc atcagtgtga tttcgtttgg
     4501 atctaattta taatctttgg ctaggcgatt tttccagtcg atcagttccc caatcatttc
     4561 aataccggta aatccagaac cacagacaac gaaagtcagc atggctttac gcagttcatc
     4621 atctggttcc aatgcagctt ttgctactgt cttctcaata tgttcccgaa tccttacaga
     4681 atcttcaaat gaccaaaggg tgaatccgtg tgctttgaca ccaggtgtac caaagtcatt
     4741 cggctctccg cccattccaa ggatcagctg atcaaaagga taggaaccta atttggtctt
     4801 gacgattttt cgttctttat cgataccgat tacagtgtct gtgacaagtt gtacattctt
     4861 ttgacgagca aacaaatgct gcagatcgta ttggattgct tctggttcta cacgtccgcc
     4921 agctacttca tgcaactcgg tcatcatagt atggtacgaa tgacgatcga tcagagtaat
     4981 tgctacatct tcttttttca gtttctttgc caagtatttt gtagctgaaa caccggcata
     5041 tcctgctcct acaacgacaa tattttgctt tgccattgat catccgctcc ttatagacta
     5101 tctatataat gaatatatga taattctttt agtttgatac ttattacaca atctccatat
     5161 attatataga tgttctgttc ttttgtctaa ctccttttgg atttttttca aattttaaaa
     5221 taaagcgttt tttcacgaaa tttgctgaaa gaaaacgttt gaaatattac atgggttatt
     5281 tatcaaaaat agttgactta taggctaaaa agattagaat gtataatgaa tcacaaagaa
     5341 aaattgtgga ctagaaatgg aatggtgggg tattaaaatg aagaaaaaac gttttgtaac
     5401 tggatttgcc gtattagcat tttcagctct agtgttaggc gcttgcggcg cagatgacaa
     5461 cggaagctca aactcttctt ctgaatcatc tacagcacaa tcttcgactg caaaaagcac
     5521 aacagaatca tctgcaaaag ttgtagctgg cggagatttg caagacggca catataaatt
     5581 agaagaaaaa aattattcaa atggttaccg tgcagtcttt gaaatggttg taaaagacgg
     5641 caaaatcact gaatcaaaat atgataacgt caatgaaaac ggcgaatcaa aaacaaaaga
     5701 tgcagaatac aacaaaaaca tggaagcaaa atctggcaca aacccagaaa aatacattcc
     5761 tgagttgaat gaccaattct taaaagcaca aagcgcaagc ggtgtggaag tcgtaactgg
     5821 agctactcac tcatctgaaa gcttccaaaa ctacgcacaa caattgatcc aagctgctca
     5881 agctggtaac acagatacaa tcgaaatcga caatggtgct gatttgaaag acggcactta
     5941 caagcttgaa gaaaagaact actctaacgg ctaccgtgtg caattcgaaa tgacagttgc
     6001 tggcggcaaa gtaactgaat caaactttga ttatatcgac aaagacggta aatcaaaaca
     6061 agatgataca gaatataatg aaaatatgaa agcaaaaagc ggtacagaac caaaaactta
     6121 catccctact ctgaacgacg aattcgtcaa agcaatgggc gaagaagatg gctcacctgc
     6181 taatgtagaa gttgttacag gtgctacaca cagctcacat tcattcatca tgtacgcaca
     6241 acaattagtg aatgcagctg aaaaaggcga cactcaaaca atcgaagtag ataatatcgt
     6301 aacagaaaaa taatcacata atcatactaa taaaagttgg agggtgggac gatagccaga
     6361 ttaggcagtc gtctcacctt tcaaaatgaa gagaggaaaa agatgcggaa aaaactacta
     6421 ttttccttaa tcacactggg catctctttt atggtgctaa ctggctgcag caactcagca
     6481 aataaaacaa ccactgaaag ttcagcagct accaagatat tgaaagatcc atattctgat
     6541 gaacagttct tgttagggac ttacgttcgt atccgtgtgt atgatgaagg caaagaatca
     6601 gcattgaaac ctgccttcga tcgagtaaaa gaacttggtg ataaaatcac gatcaatcaa
     6661 aaaggttctg agatcgatga agtgaatgag caagctggga tcaaaccagt aaaagtttct
     6721 gatgacgtct acacgttagt caagcgggcc tacgaatata gccaagattc tcaaggcgga
     6781 ttcgatatgg cgattggtgc aatcacacaa ttatggcgaa tcggttttga tgacgccaga
     6841 aaaccttccc aagaagaaat cgatcaggca ttgaaattag tggattatca taagatcgaa
     6901 ctaaatgaca aagaaaaaac tgtttatcta aaagaaaaag gaatgatcat cgatttaggt
     6961 gcaatcgcca aaggttacat tacggacgaa gtagtgaaag tcttgaaaaa acaaggagtg
     7021 accactgcca tcgttgactt gggcggtaat gtctatgtct taggccacag cccaagaggc
     7081 gaaaaccaag actggacagt cggcatccaa gatccgaaca tggctcgcgg atctgtttta
     7141 ggttctatta aagaacggaa caaaacatta gttacctctg gaatttacga gcgttattta
     7201 gaagtagatg gcaaaaaata ccatcatttg tttgatccaa aaacgggtta tccgttcgac
     7261 aatgatatcg caagtgtcac gatcataaca gataaatcaa ttgatggtga cgggttgtct
     7321 acagcagtct tttcaatggg tgtgaaaaaa ggactggaat acgtcgaaag cgaattgaat
     7381 aacgggacgg aagcgatctt cgtgacaaaa gacgataaag tatatgtgac cgatccaatc
     7441 aaagacacct tcaaattatc ggaggactcc cattacacga tgggtgaccg ttctgaacta
     7501 aaataaggag tacgaaccat gacactaaaa atctttttag aagtagttga aatacgaaca
     7561 aaggtggcta gtgtatttcc ttttgcggta ggggtattat tctctatcgc tttttttcat
     7621 gagatacatt ggctaaacac ttttttattt tttattggaa tgctagtttt tgatttagcg
     7681 actaccgcta tcaataatta catggattat gaaaaggctc attctgaagt atataagtat
     7741 gaagaaaatg tcattggccg cagaaatcta tctcctgtat tgattcgaaa catgatttta
     7801 gctatgattg catttgtttt tgttatcggc gttattctaa cgatcaatac gggttggctt
     7861 ttacttttga tgggatttat ctgttgtttt attggagtat tctatacatt cggaccgatt
     7921 cctttatctc gaatgccttt aggggaaatt ttcagtgggg tgactatggg ccttggaatt
     7981 tttgccatgg tcgtttatgt caatacattc ggttcagatg tctatgatct gacagtcaac
     8041 ttttcatctg gacaatttga tttggtagga aatctttggg ctatagcagc aatcgtatta
     8101 gcttccttac ccttggtgtt tacgattgcc aatatcatgt tggctaataa tttgcgggat
     8161 cttgaccgtg atattgaaaa tcatcgctat acactagttt tttatatcgg acgtcctgcg
     8221 ggaacagtct tattccagct attgatgtat gcttgctatt tcgtgatttt aatggggttg
     8281 ttgagcggta tctatgaatg gccgatcttg gtcaccttct tgaccttgcc aattgtgaag
     8341 aagcatttgg atcaattcaa gcaaacgtta ccccagccta tcagtttcag ctattccatc
     8401 aaaaatatgg tcttattcaa tgccagttat gtattggggc tattactaac aatcattatg
     8461 caagccattt aacagcatga agaggttgtg aaaaaactgc cctgcatcaa gtaataagaa
     8521 cagccaaata aaaatagctc cttatatttt tcgtttggtt gggcttatta ccgcagatgc
     8581 aagcttttga acaccgttta tcaggaggtt gtgaaaaagt cgcttagttt cgagtattaa
     8641 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttggctta ataccgagaa
     8701 actggctttt gaacaccgtt tatcagaggt tgtgaaaaag tcgcttagtt tcgagtatta
     8761 agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttggctt aataccgaga
     8821 aactggcttt tgaacaccgt ttatcagagg ttgtaaaatc agtgttttgt cctgagtatt
     8881 agagaaacaa atggaaaaat agttcctcat attttgccgt tttttgagct aataccgaag
     8941 gacagctgat tgaacactat ttgttcggaa aaagtgacta actatgacac aatttttttc
     9001 acagtccctt ttttcacttg atttgattcg taccagcgaa cttgacgaga actttcttgg
     9061 tttggtaact atatggtatt cttttaacat cctcgtttgc ttcttctaat ttatttatac
     9121 aaagtcacac ttttttaaac atctgttctt cgatacattt ctatttcttt taaacatcga
     9181 taccaatatt ttgaacttaa gagtgcatac caaatggatt catttactct tcgtcagtta
     9241 cgaagataat caaaatctcc aacttcccta cttatttcgt tttgagaatt atcgaagcaa
     9301 tcttacataa ataactaaaa aacaaaaaac cagaaaatca gtatactgat tttctggttt
     9361 tacatggttt gttcaataaa aagctgttgg aactgttaat attaaattat cgcatcgtta
     9421 cgaattcttc cgctcctgtt ggatggatgg ctactgtatt gtcaaagtct tctttagttg
     9481 cacccatctt gatagccacg gcaaaacctt gcagcatctc atcgacacca acaccaatag
     9541 catgtaagcc gacgattctt tcttcttttc cgacacagat caatttcatt tcgcattttt
     9601 ggcgataatc atttaatgca aagtacattg gggtaaagcg tgaacgataa actttcaatt
     9661 cattttcgcc atatttttcc aatgcttctt cttctgtcaa accaattgtt gcaattggtg
     9721 gatgcgtaaa gacgactgtc ggaacaagtt tatagtcaag ataagaatct ttctttccat
     9781 taaataaacg ttctgataaa cgtctaccag ctgcgattgc aacaggagtc agatctaatt
     9841 taccgatcac atcaccaaca gcaaaaatat gttcatccgt tgtattttgg tatttatcta
     9901 ctttgataaa cccttttttg tccaattcca catttgtatt ttccagacct aatttttcgg
     9961 tattcggtac acgtccaccg gcaaaaagta cacaatcacc agttaaggtt tcaccatttt
    10021 caaatagcac cgtatattcg tcattgtttt tagtaatttc tttagcaata tgatgtgcgt
    10081 aagtttttat tccagcttct tggtacattt ggatcaaatt gtccgaaagc attttatcaa
    10141 acgttctaag tggtcgttct tttcgatatg cccacatgac ttcactacct aaaccacgaa
    10201 atacacctga aagttcagcc gcaatgtatc cagcacctaa aacgattgct ctcttaggta
    10261 actctgttaa ttcaaaaaat ccatttgaat caattgcgta ttctccacca ggaatggtca
    10321 ttttacttgc acggcctcca gtagcgatca agattttagg agcacgatag gtttcaccgt
    10381 ttacttcgat cgtttgacta tcgataaaag tagcgtaacc ttttatagcc tcgacatgat
    10441 tgctatctaa tcctctttga taagcaccgt gtagaaaatc aatatatttt tctcgtcttt
    10501 ctactagacc ggcgaaatca acatttttta aatctgcttg gataccgtaa cttgaggcat
    10561 ctcgttcaat tgtttccaaa atcgtacttg cttgccacat aactttttta ggtacacaac
    10621 cgacgttgac acatgttccg cccaattcat tcgcttcaat cagcaaaact tttgcgccat
    10681 gcatccctgc tctgtttgct gaagcaatac cgccagagcc gccaccaatt acgatgtaat
    10741 catatatttg cattttgttc ctccttattg aagagatcaa tcaaaacctt tatttaacga
    10801 tcctttttct acagaaaaca agtgtaacac ttttcttgaa ttttgtatgc gaagatgctt
    10861 aaaacaggga tatatcagct ttttccttat ttacgttttc ggatcatatc tccaggtttc
    10921 accggctgtg cgactggcat agttaaaatc atcattggat ttggtgctcg gtcaatggat
    10981 tcgccttctt cattatgcat aacttcaacg gtttgactga aatgactgaa tcctggacca
    11041 taaaattcga tttcatctcc tacagaaaac aagtttctct gacgtatcgt agcaatctgt
    11101 gttgcctcat cataagataa tacttcaccg acaaatttat atactgggat tttacgacgt
    11161 tcaccgaata attgttcgtt ttcagttggt gtattgtagt aaaaacctgt agctaattct
    11221 cgttgtgcta ctttccataa ctcgtcgatc cattcttgct tgcagacata gttttcagga
    11281 tcttccatat aactgtctac agccgcttta tagacatttg acaccgtaga tacataatgg
    11341 atcgatttca ttcttccttc gatcttgaag ctgtctacgc cgttttcaat caattctgga
    11401 atatgttcga tcattgacat atccactgca ctcatcgaga attcttcttc cacttcgcct
    11461 gtatcagtta aactgtttcg ttcttgacca aaaggcatat cgaacaatcc atacttccag
    11521 cgacaagatt gagaacatcc gccacggttt gcatcccgca tcgacatatg gttggacaat
    11581 gtgcatcgac cagaataaga gatacacatg gcaccatgga taaatgcttc gatttcggta
    11641 tccgtatttt tacgaatctc tgccacttcc tccattgaaa cttcacgagc taaaacgaca
    11701 cgttccaacc cttcttcttt ccagaattcc aatgtctcaa aattagttgc tgaagcttga
    11761 gtggataaat ggatcggcag acctggggct tctgtcgcac aaatttcgat caaagctgga
    11821 tcagaaacaa tcactgcaga aataccgaca tcacgcaaac tgcggaaaaa ttcccctgct
    11881 ccatcttcat ttccttcatg ggtgaccata ttagcagcaa cgtatacctt cgcatcatgt
    11941 tcttttgcaa aagcaactcc ttcagccatt tcttcataag taaaattacc tgcacggctt
    12001 cttaaaccat atgcattccc gccaatatat actgcatctg ctccataatg gatcgcggtt
    12061 tttaactttt ccagtgttcc tgctggcgct aggatttctg gtcgtttcaa ttttcttttt
    12121 actgtcattt ctttcatcat actccttatt tgatagcaga aggatcaata taaaagaatc
    12181 ctgtatctaa ttcacggttt tcaggatgca atttactgat ttcgctagtc attttttccg
    12241 ctttttcttg atcccagcta ccttctaaaa tttgtttttt tgcttcggcg aatagtcgag
    12301 tgatgtttac gaatttttcg cctggagtaa ataatccgtc caatttccat gtacagtaat
    12361 gatgctgata aagttcattc aattcattcg agagattcag atcattgctg gcaaaaatat
    12421 gtgtgccatg actatcttca taaatagaat aatgtgtctc ttctttttta ggttccgaga
    12481 taaaaagacc tctttcacga tctttttgtt cgtcttgttt cgtatagtta tagtaattct
    12541 gtagcagtgg acgtttggat tgatggatgc atgtagcacc atacacaagg gtttctacag
    12601 gaatatcgag tttttcttcc atcgccttca tctcttcaaa aggaacttca cgagcaagta
    12661 ctgctccaac tgcgcctttt ttcgcccaga aattgatttg acgtgcgctc gttactaatg
    12721 tttcagcatc ataaatatac ggtatacgca attcaggatt ttttttcatc gtataaataa
    12781 tacctgtatc accaactgtg atcacatcta cgtttatttc ttttaaaaaa gccaaatatt
    12841 caggtacatt tttcattttt tcaggatgaa tgatcccatt tacagcaata ttcgcttttt
    12901 taccatactt gtgtgctaat tctaccaatt gtcgctgttc ttctcgtgta aatgaagcag
    12961 gcagacgcaa tccaaattgc tcttcaccga aatatagtgt atctgcacct gcagcaagca
    13021 actgttctgc ttgttcaata gtttctactg tggttatgag ttcgatcata attttctcct
    13081 cctacaactt cataatagta gcatagctct aaaaactttc caatacttct tctatttaaa
    13141 gtcggatttt tgaaaattat ttcacaaaaa atcaaaataa agttcgatat attctgtcca
    13201 aatataaaaa gagattgtga caaaaatctt gtcacaacct cttaatcaag tcttactatt
    13261 ataaaaattc agctacacag gccaagtaac tatagggaac ctactgtttc ctttttaggt
    13321 ccgcgaacat tcaatgtgat cttacctttt gaagcaccta ctgttacgtg gtcacctaaa
    13381 cgaatttctc cgccaagcaa agcctcgctc aatcgatctt caatttcttt ttgaagtgcg
    13441 cgacggattg gacgtgcacc atattcagga tcaaatccag ctttcccgat cacatcgatt
    13501 gcagatggtg tgattttcac ttgaatatct tgttctttca atcgtttgat aatcgctttg
    13561 ctcatgattt ggacgattgt atggatttca tctttactca atgaatggaa gacgacagtc
    13621 tcatcgattc gattcaagaa ttcaggtcgg aaagctttct ttaactcttc taagatacgt
    13681 ttttgcatgg ctttgtgatc tttagtaaca tcttggacat tgaatccgac atttttttct
    13741 tctcgaattt gtgtcgctcc gatatttgaa gtcataatca tgattgtatt tctaaagtcc
    13801 acttttctac ctttagaatc tgttaaatga ccatcatcca atacttgcag aagtaaattg
    13861 aaaacgtctg gatgtgcttt ctccacttca tctaagagaa tcactgaata tggtttttga
    13921 cgaatttttt ctgtcaactg tccaccttca tcatacccta cgtatcctgg aggagacccg
    13981 attaatcggc ttgtactgta tttttccata aattctgaca tatcaacacg gatcagggca
    14041 tcttcacttc caaacatgac ttctgaaagt gctttggcca attctgtttt tccgacacca
    14101 gttggtccaa ggaacatgaa tgaaccaatt ggacgatcag gatctttcaa tccgcttcgt
    14161 gcacggcgga tcgcacgtga aactgctttg acagcctcat cttgaccaac gacacgttca
    14221 tgcagaagtc cttccagttc taacaagcgt tcgctttctt ttttctccaa ctgctgtaga
    14281 gggacaccag tccactccga tacaactgta gcaacatctt cttctgttac acgatcagaa
    14341 taaccttgct cctgttttgc ttcaattgca gaaacttttt gcagcttttt acgtagtgct
    14401 ttttcttgtc tgcgtaattg agcagcattt tcaaagtctt gtttttggat cgctgcttcc
    14461 ttttcttgta ctagttcatc gatttctagt ttgatcacag ttgattttgt taagtgatcg
    14521 gtttgatcca aacggacttt cgctgctgat tcatcgatca aatcaattgc tttatcgggt
    14581 agttgacgag aagtgatata acgaacagaa agattgactg ctgctcgtac agcttcatct
    14641 gtgatctcca ctccatggtg ctcttcatat cttgtacgta atccttgaag aatcacttct
    14701 gcttcttcag gagttggctc atctacttga atgcgagcaa aacgtcgctc taatgcagaa
    14761 tctttttcga tatatttttg atattcatct agggtcgttg ctccgatcgt ttgtaattct
    14821 cctcgagcta acgccggttt caagatattc gaagcatcaa ttgctccttc tgctccacct
    14881 gcaccaatta aggtatgcaa ttcatcaatg aataagatta cttgaccatc attatagatt
    14941 tcgtcgatga cctttttcat tcgatcttca aattcaccgc gatatttcgt accagcaacc
    15001 aaagatccca tatcaagcat catcaggcgc ttttcttgca tgtcttctgg cacttcacct
    15061 aaaatgattt tttgagctaa cccttcagca atggctgttt tgcctacacc aggttcaccc
    15121 accagtacag ggttattctt tgtccgtcgg ctaagaatct ggataagccg tttcacttct
    15181 ctcgaacgac caacaactgg gtccagcttg ttttcttttg ctaatttcgt caaatcacgt
    15241 gctaatgaat ctagcgtagg tgttccttgc ggtgtttgcc gtttatcttg tacatttaca
    15301 tttctacgac gattcattcc ttttccagca gaatcaccag ctagccccat tttttgtttc
    15361 agaacttgac gggcttttga aaggctgata cctaagttga tcatgattcg agtagccatg
    15421 atactttcat cttttaataa gctcatcaaa atatgttctg ttccaacttt ttgagaacca
    15481 gttttcttca cttcgctgct agctaaagca aaaacttgtt tcattcttgg tgaatatgga
    15541 agaaagactc ctttagggta agaacggata ccaccataac caatcagatg ttcaatttct
    15601 tcataaattt ccgtttcatt caaatccatt tcacgtaata cttttccagc aattccattt
    15661 tgctcgacca ctaaggctag taaaacatgt tctgaactaa ctgattgatg tttcaaccgt
    15721 tttgcttctt cttgtgcaat ttctaatact gcttgggctc tttcagtaaa aagttcttcc
    15781 atctaatctc acttcccatc ttcataactt aaacgttcca gaaatgctcg gagaatccga
    15841 gcacgtgtat gatcttcata ttcattgaaa ttcaatgtgt tttttgcaat tgcactcaac
    15901 atcaagtttc cttctttttt tgtaattatt tggtcttcat aaagtttttg aataatagca
    15961 aaagcatttt tctcactgat tgtatcatca aataactgat ttatctgctc aagtaattgt
    16021 tttttatctg aaatccttac ttttgcaatt cgtatataac caccaccacc acgtttgctt
    16081 tctactagat aaccacgttg gatggtaaaa cgggtattaa tcacatagtt gatttgtgaa
    16141 ggaacacagt taaagaggtc tgccatttca atccttcgaa tctcgatcat ttcactattt
    16201 tccagaattt tctttatata tgattcaatt aaatccgagg tattctgatg tgccatctta
    16261 ttcattccct ttgactaata ttgaccttaa ttataacgaa tttgataata gaaagaaaga
    16321 agaacgcttt ttgttaaata aatcctttag aatcaacaaa aaaaaatacg gaatatacta
    16381 ttccgtatcg acgcgcccaa gaggagtcga acccctaacc ttttgatccg tagtcaaaca
    16441 ctctatccag ttgagctatg ggcgcatatt caatttaaaa aaattataaa tcatttgaaa
    16501 acaaaaagca agataaaaaa aatcgggaag acaggattcg aacctgcgac cccttggtcc
    16561 caaaccaagt gctctaccaa gctgagctac ttcccgttta aaaaataaaa aagac
//
LOCUS       DAYNVV010000056        16050 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.059, whole genome shotgun sequence.
ACCESSION   DAYNVV010000056 DAYNVV010000000
VERSION     DAYNVV010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16050
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.059"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            172..516
                     /locus_tag="ACGXWR_002130"
     CDS             172..516
                     /locus_tag="ACGXWR_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFK0803660.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            517..936
                     /locus_tag="ACGXWR_002131"
     CDS             517..936
                     /locus_tag="ACGXWR_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFK0803661.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1028..1378)
                     /locus_tag="ACGXWR_002132"
     CDS             complement(1028..1378)
                     /locus_tag="ACGXWR_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803662.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1344..2675)
                     /locus_tag="ACGXWR_002133"
     CDS             complement(1344..2675)
                     /locus_tag="ACGXWR_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HFK0803663.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2930..3496
                     /locus_tag="ACGXWR_002134"
     CDS             2930..3496
                     /locus_tag="ACGXWR_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFK0803664.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3641..3728
                     /locus_tag="ACGXWR_002135"
     tRNA            3641..3728
                     /locus_tag="ACGXWR_002135"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3673..3675,aa:Ser,seq:cga)
     gene            4064..5038
                     /gene="bsh"
                     /locus_tag="ACGXWR_002136"
     CDS             4064..5038
                     /gene="bsh"
                     /locus_tag="ACGXWR_002136"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFK0803665.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNINKEDLDRHELVSYPVIKEQQINYVN"
     gene            5363..7258
                     /gene="asnB"
                     /locus_tag="ACGXWR_002137"
     CDS             5363..7258
                     /gene="asnB"
                     /locus_tag="ACGXWR_002137"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HFK0803666.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKLDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(7453..7899)
                     /locus_tag="ACGXWR_002138"
     CDS             complement(7453..7899)
                     /locus_tag="ACGXWR_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HFK0803667.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            8127..8276
                     /gene="rpmG"
                     /locus_tag="ACGXWR_002139"
     CDS             8127..8276
                     /gene="rpmG"
                     /locus_tag="ACGXWR_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFK0803668.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            8364..8882
                     /locus_tag="ACGXWR_002140"
     CDS             8364..8882
                     /locus_tag="ACGXWR_002140"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0005542 - folic acid binding [Evidence
                     IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFK0803669.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(8959..9915)
                     /locus_tag="ACGXWR_002141"
     CDS             complement(8959..9915)
                     /locus_tag="ACGXWR_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFK0803670.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            10081..10887
                     /locus_tag="ACGXWR_002142"
     CDS             10081..10887
                     /locus_tag="ACGXWR_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0803671.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKITLLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            10884..11873
                     /locus_tag="ACGXWR_002143"
     CDS             10884..11873
                     /locus_tag="ACGXWR_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFK0803672.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            11870..12874
                     /locus_tag="ACGXWR_002144"
     CDS             11870..12874
                     /locus_tag="ACGXWR_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFK0803673.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIGLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            13006..13548
                     /locus_tag="ACGXWR_002145"
     CDS             13006..13548
                     /locus_tag="ACGXWR_002145"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HFK0803674.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            13568..14266
                     /locus_tag="ACGXWR_002146"
     CDS             13568..14266
                     /locus_tag="ACGXWR_002146"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HFK0803675.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            14287..14499
                     /locus_tag="ACGXWR_002147"
     CDS             14287..14499
                     /locus_tag="ACGXWR_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HFK0803676.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            14499..15461
                     /locus_tag="ACGXWR_002148"
     CDS             14499..15461
                     /locus_tag="ACGXWR_002148"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HFK0803677.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRYLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACANLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            15479..15874
                     /locus_tag="ACGXWR_002149"
     CDS             15479..15874
                     /locus_tag="ACGXWR_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFK0803678.1"
                     /translation="MVLWVINIILLLIVLAIIFWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
BASE COUNT         5142 a         2702 c         3308 g         4898 t
ORIGIN      
        1 ataaaaaaag cgttagcaac tatgcttaaa aagcatatcg actgaataaa ctaagcattg
       61 gacaggctga aagactacat ttaaaatgaa atgcgaagaa acaatagaaa ataaagttgc
      121 cttagaacca tagttgaatc acctaacagt cgtgaaggga gaataagaga aatggcagaa
      181 aaacaaaccg caggacgaga tcaattagga gattttgcac caaaatttgc agaattaaat
      241 gatgatgttt tatttggaca agtatggtcc agagaagaat tatctgctca tcagcgtagt
      301 atcatcacca tatctgcatt aatttcagga ggaaattttg aacaattgcc agctcatctg
      361 aagattggca agcaaaatgg cattactagt gaagaaatag cagaaatcat tacccattta
      421 gctttttatg tagaatggcc aaaagcttgg tcagctttta gtttagcaaa agaaatctat
      481 ttagaagaaa atagcgaaga taagaaagag gcgtaaatga tgacaaaaca cgaagaaata
      541 cacaatggcg tgatttttcc agcaggtgaa aaaaacgaag cttacgctca agtatttacc
      601 gggcaaagct atctgaatat gttagtgaat gatcccgaag tttctgttgg tgtaggtaat
      661 gtaacttttg aaccaggttg tcgcaatcac tggcatgtcc atacagacgg ctatcaaatc
      721 ttacttgtga ccggaggaga aggctggtat caggaagaag gaaagccagc aagacgatta
      781 atggctggag atgtcgtcgt aacgcacaaa gggattaaac attggcatgg tgcgacaaaa
      841 gacagttggt ttgaacattt ggcgatcact gctggtaatt cagagttttt agaacctgta
      901 acagatgaag tgtatgaagg attggaaaat caataatgtc aagcttgaac agctcctgaa
      961 agtagatttt aatcgaactt tcaggagctg cttttttgat tcagtctttt ataaatagaa
     1021 aatagggtta ataataggaa tgagaagcac gtcgaaagat cttaatattg ataatcggct
     1081 gggcatacat gatttccacg tcatcaatca aactacctaa cagatgataa tcttcccgat
     1141 catgtcgggg attacctaat agttcttgat agtagatttc catactaggg tcccgaggat
     1201 tgttcagcaa atcagcaagt acatctaaat cttctggctg agtttctgcc gtaccctgta
     1261 tctctatgaa aagcccttcc tcagcaaatt ctactccaat acgtatttca gttatttcat
     1321 gggaatataa ataagtaaga agctcatcga tgattctttt tgataattct ttttccaagt
     1381 gtcttttttt cctttctgac agcggtaaag ttatctagta tcggtacaag gatacctgca
     1441 acgaaaccag ttgaaaaacc actgttatat agatttagtc ctccgtgcaa agtgctgacg
     1501 ttatggacaa gagcaatatg tagcacacca gctattacac cgtaaaaact gccgtaaaaa
     1561 ccgcttatgg gcgcaagacc tgtcccaaac acagctgcaa caagcatgcc agtactggtg
     1621 atctcatgaa aagttccaaa caaagaagca ataaatattc cgactagtat cggaaaactg
     1681 ttttttaaat gacaaccaaa agcactgaaa cccaccgcag ataaaatagc accgatgaca
     1741 ggtccattta actgaccgcc aaccagcaaa acataagaag acagcatcag accaactaag
     1801 cccatgttga tcaaagtagc accaatacca gaattagcaa tgaaatcagt tgtcaatttt
     1861 ccagatgaat cgaaaatttc tcgaatcccc gaaagccgaa aggaattata atagaaacca
     1921 attccgactg tcagcgaaaa aaagccaaaa ataatccaaa tgagaggaaa gtgatattca
     1981 ttgaaaacca atgtattttc gacgattgaa tagctgaata acctcaaaac agcagtaaaa
     2041 gtcatcgcaa tcaacccaga ggtgaatcca atattataaa gtgtgaatcc acgatggaaa
     2101 actaaagttt gagcagctaa gggcggaaga agtataccaa ttgctatgcc agctaaattc
     2161 cccaataaaa tacctatcag taaaggaaaa cgcataccaa aagtgatata actaacgacc
     2221 ggtgataata cgctaccaaa cagtccgatc atgatgtact gagaaaaagg tttattgaca
     2281 aatacagcgt atagatacac acctaaaatg attgagatag aattataaag gtttttgcca
     2341 aaaaaagaga aaccggtaac tgttagaatc gaagcaaata agggaccgtt taaaatcacc
     2401 ttgtgccgat aagctaaaag cacagaaagt aaggtcaaaa tccctacatt tatgaatgcg
     2461 cttccgaaaa cacctaaagc aaaataatct gtcaaaagat tgcttggcga ggtaagaata
     2521 gttagcaatc cactccaatt atcagtagga gtattagaaa gcaagccaat aaaaagaaaa
     2581 aaaacacctg taaaaccaag ataaaaatac tttcttttct gtgaaacgat tcgtttttga
     2641 ggatgaatat aaataacgtc agtttcgttt tccattacac accttctttt tcattttctt
     2701 taactataac ttgaaatgaa agatttggac aactatcatt taggtcaaaa ctaaaaatgt
     2761 aagggaaccc attgaattta accaaatttt tttaattttg caaaaaaaag ttaaagaaga
     2821 ctgaaaaaaa tttaaaatat aacgttttga gtaaaatgtt tgcaaaaaat gctaaaaata
     2881 gggtacaata aaacaacata tactgcagta aagaagtggg ggagttttaa tgagaagaaa
     2941 agtctatacc aaggatcaaa ttctaaaagc tgcttatgat gttgttgcaa aggaagggtt
     3001 taaaggattt actgcgagaa atattgctaa aaagatgggg atttcgacac agccgattta
     3061 tctggaattc aaaaacatgg aagatttaaa aaatacgttg ctggattcta tctttgaaca
     3121 actaaaagaa gatgttttcc ctattgaacg tactggtgat aaaatcattg atctcggttt
     3181 gaactatatc tactttgcaa aaaagcatca tagtctttac atggcattgt acattgatga
     3241 acatggggac ggaaagaaaa tgcatgattt ttcatacaat tatttccgtg aaatagttaa
     3301 agaagatgaa agatacaatc aattatcgga tgaatatgtc gatgctctgc atactggtac
     3361 atgggtagca gtgactggct tagcgtcatt gatgtcatca aacatcatgc atccaacaga
     3421 agaacaaatc attgcactga tcaaacggac aattgactcg attttagcat tagataatcc
     3481 tgaaataatc agatagtgtt ctatcagtat gaatttgatc ggtaagtccg ttggctgcaa
     3541 actgtcaatg gacttttttg ctaaaaaaag cgatttctgt tatttatcta ttagaaatag
     3601 gcttgacatt tcgtgaaaaa agtttaaaaa tagtacttac ggaaggttgg cagagtggta
     3661 atgcaccgga ctcgaaatcc ggcgaaccgg ctaataccgg cgcgcaggtt caaatcctgt
     3721 accttcctta tatcaacgat tagaggttgt gaagaagctg tcctgcatca agtaataaga
     3781 acggccaaac aaaaatagct tttcctattt tttcgtttgg ttgggcttat taccgcagat
     3841 gcaagctttt gaacaccgtt tgttcggaat aaggggctgt gacaagactt ttgtcacagc
     3901 cccttattgt tgtactttta acctacaata ttttttgatt ccccctgagt actatttttt
     3961 ataaatgcta gtaaatcaat cttctttggc cttttttttg ataaaaaaaa atactagatg
     4021 taagataaaa gtgtaaaaac gatttgtttt aggagggaaa acgatgtgta ccgcaatcac
     4081 ttatgcaacg aaagaccatt attttggaag gaattttgat tatgagatgt cttataatga
     4141 agtagtcact attactccaa gaaattatcg tttcgatttt agaaaggtaa aaaatttaga
     4201 taaacattat gcaatgatag gaatagcagc tggggtatcc aactatccac tctattatga
     4261 ggctacaaat gaaaaagggt tgagtatggc aggactgaat tttcctggca atgctgatta
     4321 taaagaatta caagaaggaa aagataacgt tgcaccattt gagtttattc catggatact
     4381 agggcaatgc tcaaccatag acgaagctaa agaattattg gctactatca atctagtcaa
     4441 tatcgatttt agtgaaaaac tacccttgtc acctttacac tggttattag ctgataaaga
     4501 aaaatcgata gtaattgaaa gtatgaaaga tggacttcat ttatatgata atcctgtcgg
     4561 tgtgttgaca aataatccgc catttgatta tcaattattt aatctgaaca attatcgctc
     4621 gctatcaaat ggaacaccag aaaatcattt ttcaaaccag atcagcttga atgtttatag
     4681 tcgtgggatg ggaggattgg gcttacctgg agatctctct tctgtttctc gatttgtaaa
     4741 agccacattt actaaaatga atgctgcatc aggtgattca gaatctgaaa gtatcagtca
     4801 attttttcat atactaggct cagtcgagca acaaaaagga gtatgcgata ctggagaagg
     4861 aaaatacgaa tatacgattt attcttcttg ctgtaacgtt gataaaggga tttattatta
     4921 tcgtacgtat gaagacagtc aaattactgc tgtaaatata aataaagaag acttggatcg
     4981 tcatgaattg gtcagttatc cagtcataaa agagcaacag ataaactatg tcaattaatt
     5041 aatgaataga tccgtttggt atcatatttt ctgatacagt cataattaga cacgatcttt
     5101 aggtcgtgtc tttttttgct gttttttttg gaaatagcat ccactaatat ttttttaaca
     5161 cgaagagaat aaggtagcct caaaaaagaa aacatggtaa attagatatt gggactttat
     5221 tttctgtaaa aacagaaact ttcatctttt gttttcacgt gacgaaattg taagagagaa
     5281 aatattcgtc cgctatttat tctatgataa gatgcatatg aatgaaataa acagtaattt
     5341 tatattagga tgtgaaagtt aaatgtgcgg tattgtaggt tttgttaacg acaaggacaa
     5401 caaaaaaaca attattaata caatgatgga tcgaatcgtt caccgtggac ctaatagttc
     5461 aggagaatat atcgataaac atgttgcttt aggattcaga agattaagta ttattgactt
     5521 agagggcggt actcagccta tttacaatga agatcggaca aagatcatta tttttaatgg
     5581 cgaaatctat aattaccagc ctttgagaga agaattgatt gcagctggcc acgtttttca
     5641 aacacatgca gatacagaag tccttttgca tggttacgaa gaatggggaa cagaattatt
     5701 gcaaaagatc cgcggaatgt ttgcttttgc tatttgggat aatgaaaaga atgagttatt
     5761 cggtgcaaga gaccactttg ggatcaaacc atattattat gcagaaatga acggaacatt
     5821 tatgtttggt tcagaaatca aaagttttct gcctcatcct gattttaaca aagaattgaa
     5881 caaagaagcg ttgaaacctt atatgacttt ccaatattct ccattaaacg gcgaaacatt
     5941 cttcaaagat gtctatcgtt tgcctgaagg ccattattat acgtataaag atggaaaact
     6001 agacattcag caatattggg atgcagattt tgaaacaaaa gaaacgcatt cccgacaaga
     6061 atggatcgaa aaaatcgacg aaaccgttca agcttctatt gaagcacata cggtcagtga
     6121 tgtagaagtt ggttctttct tatccagcgg ggttgattcc agttatgtaa cctctgtatt
     6181 gaaaccagat cattctttct caatcgggtt tgatgataaa acctataatg aagcgattga
     6241 agccagaaaa ctaaccgaac tattggactt agataataca gcagcagtga tcgacggaga
     6301 catgtcgttc aaagcattcc ctttgatcca gtatcactta gatgaacctg attcaaatcc
     6361 ttcttgcgta cctttgtact ttttagcaaa tcttgcttca caaagtgtgc gggtagtcca
     6421 atctggagaa ggggcggatg aactgtttgc gggataccaa acgtatggat tccatacgaa
     6481 ttcaaaattc atccgtgtga ttgctcaagg attgaaaaaa ttaccaaaag gaacacgcta
     6541 taatttagga cgtaaaatcg gaaaaatgaa aaatttccat ggacggatcc atttatatga
     6601 atcacttgct cctgcaaaag aatattttat cggtcatgct cgagtgttcg aagaatcaga
     6661 agcatcagaa gtgttaacac caaaatatca aacagcacca tctgtggatg aaatcatgac
     6721 tgttcattac gagaaaacag aaggaatcaa agatgaagtc aataagatgc aatatgtcga
     6781 tcttcatcaa tggatgccaa aagatatctt gttaaaggca gataaacttt ctatggcaag
     6841 ttctttggaa gtccgagtac ctttattgga tatcgaagtc atgaaattgg ctcaacaaat
     6901 accaagtaag tttttattga atcaaaacaa cacaaaagat attttcagac aagctgcgaa
     6961 caaacatctt ccggaagaat ggtcgaatcg tgtgaaatta ggattccctg tgccaatcaa
     7021 agcttggttg aaagaagaac acggctacga acaagtcaaa gcattattcg aagcagattt
     7081 tgcaaaagaa ttttttgatc aagaaaaaat catgaagttg ctagatgacc atcacgaagg
     7141 acgtaaagaa gagcaaagaa aaatctggac aatcttcagt ttcttgacat ggtataaagt
     7201 ctactttgta gatgaaacga ttccgcaagc agaagcaatc gactatgtga ctgtttgatg
     7261 aaaatcaaat atcaataaaa aagaggtttt ctcctaccgt ttaacactga gtgataagaa
     7321 acaatttcaa aaaacagctc ttcccgtttt atagatatta tgacttatgg ttcggagttg
     7381 gcagaggaac accattgttt cgaacataag ggggttgtga cacgattttc gtcacaaccc
     7441 ctttacatat gttcaataat cgatttcttt ttcttttgtc ccatcttttt tataaatgaa
     7501 caaagttgat tctttgtttt gtgctacttg ctttcctttt tcgattgctt ctttttttgt
     7561 atcaaaatgg ttgcttgcct tttttgcccc tttagatttc acgatccatt gttcttcctc
     7621 atattctacg atcacatctg aatcaagcag ttttccagca cgaggattcg tatcgtgttc
     7681 atccgtcttg cttggatttt tttctttttc gaaagttcgt ttttctgatt cactagcatc
     7741 ttcataccat ttttttgctt gatcaatggc aattgggatc gcacggttat cagggtaccc
     7801 ttcatctaat aatgcatttg cgatgtcgat tgcttttttt cttgtcaatt tatctaagtt
     7861 tttcattgat gcaggaaagt ccttcatgtt ccatggcata ttagtatccc cctttattaa
     7921 aaaacataat ctatataaac aagtgtaagg gtatttatac aaaaagaaaa agattttgtt
     7981 tgagaagtaa aaccgttgta tttatcgtca agtagtttta cttaacaaaa tcgtgaaaaa
     8041 cactagcaat ctagaaaaaa tcatggtaag ataatcaagt ctgagagtca tcttagagga
     8101 ttcttgtaaa aatgggaggg aaaaacatgc gcgtaaacat cactttagag tgtacttctt
     8161 gtaaagaacg taactatcta acaagcaaaa acaaacgtaa caatcctgat cgtttggaaa
     8221 aacaaaaata ttgcccacgc gaacgcaaag ttactttgca ccgtgaaaca aaataatgtt
     8281 tttaaagttc tcaattcctt gctggtcaaa gaattgagac tttttttatc tcaaaacatc
     8341 taaaatcata aggagcggat aatatgttta tttccatgtg ggcacaagat aaaaatggtc
     8401 tgatcggcaa aaatggtttg ttaccatggc gattgccaaa tgatatgcgt ttctttcgcg
     8461 aacatacaat ggatcgaatt ttagtgatgg gaagaaagac ctatgaagga atgggggatc
     8521 tttcacttcc ttatcgccat atcatcgtgt tgacaacgca accaaatttt cgcacgaaag
     8581 aaaatgcgga agtaatgcat tcgatcgatg aacttttgtc gtatagtcaa acgatctcag
     8641 aagatatcta tgtttcgggt ggtagtcgga tttttcaaga acttcttcct tacactggtc
     8701 ggatctggcg aacattgatc gatagcacgt ttgaaggcga tacgtatatt gggaatattg
     8761 atttttcaga cttcgccctt atagaggagt atgaggggat aacggatcaa gaaaatctat
     8821 atgcccatcg ttttcaaaaa tgggaaagag taaaaaatag ggttgcttca aaagaagaat
     8881 aaaatctatg cgtctagttt gttaataaga aaaaaagcat ctcacgacta atcgtgaaga
     8941 ttcttttttt agttaaaatc aatttagttt ttctttgata tcattgacca tttcctgact
     9001 ggcaataggt ccgttatata gccaactaga ttcaggtccg aattgcagta catgattgtc
     9061 tgtcactgct ttaagattct tccagcttgg ttcattgaac atggcagcat ctttgtcact
     9121 gttcacaagg atgatgtagt cagcatctaa ttcagctagc ttttcagagg aaacagcaga
     9181 ccagtcagaa gtggcttttt tggagacctc ttccactaga tcaggaacac caaattccag
     9241 atcgtcgtat acgattcttc cacttgaccg atttttgctg accataaagg ctgagttgtt
     9301 ggtcacccac aacactgcag ctgtcttgtt ctcgatttta tctgctagtt cttctcgagt
     9361 tttcttgatg gatttttgat aatcggaaat gattttttct gcctcttttt cttttgccaa
     9421 agctttgccg acatctttta gttgttcttc ccatgtgaca tctgttccgt tttttacaac
     9481 ataagttggc gcgattttgc tatattgttc gtatttcccg ccttcgacag tagcggaaga
     9541 agaaatcaac agcaaatcag gctcaaagct taacactttc tcataaggaa ggtcataaga
     9601 aatcgttggg acatccttta aatcatcttg cagataatct tgaatggaac cactgccaac
     9661 agtccactgg gcgataggtt tttcccctag tgcaatcaga tagtcttcta agtaactgcc
     9721 gatgatccgt ttgggcgcgt ttggaatctc tactttatgt ccaagtgtat ctgtgactgt
     9781 atgagtacta ttggatgaag tcgtcgaatt ggcagttgta gctgtttctt tatctgaaga
     9841 gggggagcaa gcgctcagta ctccagccag cagcaatatg ctagataatg tgaatacttt
     9901 tgtttttaat ttcatttctt tcctcctaac ataattgaga atctttctca ttggttatta
     9961 ttcctgatat ttcgaacgct gtcaaccgct tcatttggct atagatatga aagtagcgct
    10021 tgacgaaatg ttgaaacagc gtcataattg agaatgattt tcagcgaaag gatgggtgaa
    10081 atgacgagat taagagcagc tgacattgca gccggctacg aaaacaaaaa aatcattgaa
    10141 aacatgtctg ttacgattcc tgaagggaaa atcactagtt tgattgggcc aaatggaagt
    10201 ggaaaatcta ctttattgaa aagttttacc cgtatactac ctgtgaaatc aggaaagatc
    10261 attgtcaata actctgatat ctctacatac agttcaaaag aacttgcaaa aaaaattaca
    10321 ttattagcac aaactagtga acaccctaca ggtatgacag tagaagaagt agtatcttac
    10381 ggacgatacc cttatcaaaa actgttcagt ggcatggaca cgcaagatca tgaagcaatc
    10441 gagtgggcgt tggatgctac aggtctagct ggatttcgta tgcgggatat cgcaacgctg
    10501 tctggtggac aaacccagcg tgtctggatc gctatggcgc ttgctcagga aacagatatc
    10561 ttgatcttgg atgaaccgac aacattttta gatccggcac accaattaga gatcctacag
    10621 ttattgactg aaatcaatca aatgaaacaa acaacgatct tgatgtcgat tcatgacatt
    10681 aatcatgctt cacgtttttc agattattta ttagcaatga aaaacggtaa gttgatcaca
    10741 gaaggtacac ctgaagaagt gatcacaaaa gagtgtatga aaaaaatatt tgagattgat
    10801 gcaacgattg tcacgcttcc aagaacaaat aaaccagttt ttctaaccta tgatttgttg
    10861 ccaaaagagc aggaggatca attatgagga ctatgaagaa aaatagactc ctgcttttgg
    10921 tctgttttgt tcttttgatt attttttttg ttgctctttc aaatggcgca gcgactgtgg
    10981 gaaaagcaga tttttggcag gcgttgtttg attttgatag atcaaaacaa agtcaccaaa
    11041 tcatacgaaa tattcgtttg cctcgtgtgg cgggagcatt tcttgtaggg agttgttttg
    11101 cattgagcgg tgcattgatg caaggagtga caagaaatcc tttagcagat tcaggcttac
    11161 taggaatcaa cgcgggtgct tcgttggcaa tggcccttag ttttgctttt tggcctaaag
    11221 cttctgattt ttctgtgttt ctaatgtcat tggcaggttc ttttgctgta actttgctcg
    11281 tatttggttt tttgcagttt tcgaaaatgg gcatgaatcc tttacagctg attttagctg
    11341 gcgtagctat tagttctttt tttactgcta tcagccaagc acttacccaa ttctttaatc
    11401 tgcagcagga tcttgctttt tggtttgtag gcggagctgc caatatcaca tggaaacaat
    11461 tagcagtatt gtttccttta tatatacttg ctgttttggt ttctttttca ttaggaaaag
    11521 caatatcttt gattcatttg agtgaaacac atgcattagc tcttggaagt catcctaaac
    11581 gaacgcggtt gattgttttc tgtctagttg cagtgttagc agccattgcc gtttcgttag
    11641 tcggacctgt ttcatttatt gggctgttgg ttccgccagt tgttcgcgga atggttggaa
    11701 cggactatcg ttatgttcta cctgtctctt ttttagttgg cggtggattg gttatgttgg
    11761 cggattttac agcgaggatg atcaatcccc cttttgaaac accttttgga ttagtcattg
    11821 cattgattgg cgttccgttt ttactgatac aagtaaggag ggaacaacgg tgaaaaaaat
    11881 atattggacg ttctatttct tgctttttgt acttgtcatc ctgtctatag gtagtttaat
    11941 gattggtacg ccttttattt acctggatca gctttttgcc acgttcatag ggaaagaatc
    12001 atcttctttg gcgctgattg ttagagaatt tcgagttcct cgattactga tcagtttatt
    12061 agcaggagct tgtcttggcg tttctggtta tatcttgcaa ggagtaacaa gaaatgaatt
    12121 ggcagattct agtatattgg gcattaatgc cggagcagga tttttagtga tgctttattt
    12181 aggtttcttt tcgcactatt cgctgccgtt tctattgcta gttgtagcct ttctaggtgg
    12241 tgttttagct gcttgctgtg tctatcttgc ggcctatgat cgaaatggct ttttgggtat
    12301 gaatcgaatc ttattgtccg gtattgccgt taatgccggc ctttctgcat taacattgct
    12361 atgcacgatc caattatcta aggaaaatta tggatttgtg aatgcatggt tagcgggatc
    12421 aatctggggt gcgagctggc cttatgtttg ggcattgctt ccatgggcgg ttatcttaat
    12481 tccgctagga ggactttatg cacagaggat tggattgcta tcatttggtc aagaacgcgc
    12541 gcaaggatta ggccttaacg tggctaaaag tcaaaaaatc cttttgttgt tagctgttgc
    12601 tttggcaagc ggtagtgtag cggtgacagg tagtttatct tttgtaggac tactagctcc
    12661 tcatgctgcg aagctagtcg tacgtaaaga aaataactgg acctttgttc tgagcggttt
    12721 gttcggttcc atttttctgc ttagtgcaga tatggttgct agagtgattc taccaagtgg
    12781 ggaagtacct acaggaattt tgattgccct ttttggtgcg ccatattttc tgtatgcact
    12841 ttttatcaga caaaaacacg cgctgaacag ttgaaattta ttaaaaaagg aaggccaatc
    12901 atttctaggt cttcttttta ttctatttat gcatttattt gaaagttcga ttgctatttt
    12961 tctttttttc ctataccatt ttatgagaga aggaagggtg agtttttgga ccaattgaaa
    13021 gtaagattac gccggaaagg aatcgaaaag ctgaaaaatc tggccaaaag tggcaagaaa
    13081 aaggaaaaag aacagcgaat ctataaacag ctattcgcca gcgagtactg gaagtcagca
    13141 aaagtgatag ggacgacttt atcgaatgaa tttgaactgg atacacagcc ggttatccaa
    13201 cgagcagaaa aagaacaaaa gaaaatagtt gtacctaaaa ctttgccgaa acgtcagatg
    13261 gcgttttatg aaatggatga acagtccgtt cttgtacgtt cgagttttgg tgttcttgag
    13321 ccacaatcag agaagctcta tttgccggag atgatcgatc tcctcattgt accaggtatt
    13381 atctacaata gagccggtta tcgaatcggt tttggcggtg gttattacga ccggtattta
    13441 aataattttc ataaaaaaac atgtagcctt gtttttcgtg aacaattgaa tgaacaatgg
    13501 caaccggaga gctttgatca gaagatccaa caattgttta ttgactaaaa tgaaatggga
    13561 ggttttcatg aattatcaac agcaaataaa attgcgtgca tggttaagac gaccgttatg
    13621 gacctatgct tttttaggga tacagacagc ggtcttcctc atgatggaat tatttccgcg
    13681 acttgagatc ccttattatg ccggaatgta tggtccttat cttgttcact tcaatgaatg
    13741 gtggcgttta gtgacaccaa tcttcatcca ttttggactg atgcatttcg taatgaactc
    13801 actgatactg tattttatgg ggcagcaaat cgaggcaatc tatggccatt ggcgtttttt
    13861 cttgatttat atgttcagcg ggataatggg aaatacagca agctttgctt ttaacgaagc
    13921 gaatgttctg tctggtggtg cgagtacttc gatattcggt ttgttcggtg cgttgtttat
    13981 cttagggttt cattttaaac ataacccagc gatccagcag ctagtcagac attttctttt
    14041 atttattgtg ttgacatttg tttttggtct tctggatacc tctgtagatg tttggggaca
    14101 tgtcggtggg ctaattggcg gattagtgtt agggaatgtt ttgggtctac cgaaacaaca
    14161 gacaagctat tcgatacacc aaaggattct ttctacacta gtttttgtat ttctttttgt
    14221 aatatgtatt ttactgggtt taaaaaaata tggtttactt gtataatatg aaggaagtgc
    14281 ttaaagatgg agagcttata tgatgtacag cagctgttca aaaaatttgg catctttatc
    14341 tatgtgggtg cacgcatcta tgacattgaa ttaatgacta tcgaattgcg taatctgtat
    14401 gatagccgtt tgattgatca tgatacatac atgacagcgt ggcgcatatt aaaaagagag
    14461 caccgaattg aagaaagccg aaagaaagga aatttgtaat ggacaagaag attattggga
    14521 ttgatttagg tggaacaaca gcaaaatttg caattttaac accagaagga gagattcaac
    14581 aaaaatggag catcgatacc aatattttgg atgatggtaa gcatatcgtt cctgaaatca
    14641 ttgaatcaat caaccatcgt ttgaatttat ataatatgaa agccgaagac tttatcggaa
    14701 tcggcatggg taccccagga agcgtggaca gcgaagctgg aacggttatt ggtgcgtata
    14761 acttaaactg gacagaagtt caatttgtga aaaaactgat cgaggcagga acaggaatca
    14821 aattcgctat cgataatgat gcgaatgttg ctgctttagg tgaacgatgg aaaggtgctg
    14881 gagaaaacga tccagacgtt gtattcgtta ctctaggaac aggtgttggc ggtggtatcg
    14941 ttgctggcgg aaatttgatt cacggcgtga gcggagcagg cggagagatc ggccatatca
    15001 ctgtggatcc tgaagggttc gaatgtactt gcggtaaacg cggatgttta gaaactgtgt
    15061 ctagcgctac tggtgtggta cgtctaggtc gttacttggc agaagaatac gcaggagatt
    15121 caaaactgaa agcaatgtta gacaacggtg aagaagtaac aagtaaagat atctttgaaa
    15181 tggctcaaga agacgatccg tttgcattga tggttgttga tcgcgtatgc ttctacttag
    15241 gtttagcttg cgccaacttg gggaatacat tgaatccgtc aagtattgtg ttaggtggag
    15301 gagtatcggc agcaggagaa tttttacgta gccgtgtaga gaaatatttt aaagaattta
    15361 ctttcccgca agtaagagaa tcaacaaaaa tcaaattagc agagcttggt aatgaagctg
    15421 gtgtcattgg tgctgcctca ttagccttga aatttgctta aaaaaacgga ggcattacat
    15481 ggttttatgg gtaattaata tcattttgct attgattgtg cttgcaatca tcttttggga
    15541 agtctatcta cgagtaatgg ccaagcgttc agcaacgact ttgacagaag aagaatttcg
    15601 agaaggaatg agaaaagcac aagtaatcga tgttcgcgaa aaagatgtgt ttgatgctgg
    15661 gcatatttta ggtgcaagaa acatccctta cactgttttg aaagattcat taggatctat
    15721 tcgaaaagac cagcctgtct atatttacga tcaaaagaaa agcttgagca tccgtacagc
    15781 aaataaatta cgtaaagcag gttatcaaga gatttattta cttaagggtg gatatgacgg
    15841 atggtctgga aaaatcaaaa gtaaaaaagt ataaaacaga tgattgtatg acagctttaa
    15901 aaaccgaatc aatcattaga ttttgaccaa gatcacatga acggcgcaat ggatagttgt
    15961 gccgttcatt ttttttattt tgtgctatta tctacatata taagctaagc gaaaaggcag
    16021 aaagaaggaa acaactatga tcaaattaaa
//
LOCUS       DAYNVV010000057        15993 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.060, whole genome shotgun sequence.
ACCESSION   DAYNVV010000057 DAYNVV010000000
VERSION     DAYNVV010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15993
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.060"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(69..1208)
                     /locus_tag="ACGXWR_002150"
     CDS             complement(69..1208)
                     /locus_tag="ACGXWR_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HFK0803679.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1607..2905)
                     /gene="eno"
                     /locus_tag="ACGXWR_002151"
     CDS             complement(1607..2905)
                     /gene="eno"
                     /locus_tag="ACGXWR_002151"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HFK0803680.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            complement(3021..3776)
                     /gene="tpiA"
                     /locus_tag="ACGXWR_002152"
     CDS             complement(3021..3776)
                     /gene="tpiA"
                     /locus_tag="ACGXWR_002152"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HFK0803681.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            complement(3880..5070)
                     /gene="pgk"
                     /locus_tag="ACGXWR_002153"
     CDS             complement(3880..5070)
                     /gene="pgk"
                     /locus_tag="ACGXWR_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HFK0803682.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            complement(5180..6181)
                     /gene="gap"
                     /locus_tag="ACGXWR_002154"
     CDS             complement(5180..6181)
                     /gene="gap"
                     /locus_tag="ACGXWR_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFK0803683.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            complement(6222..7313)
                     /locus_tag="ACGXWR_002155"
     CDS             complement(6222..7313)
                     /locus_tag="ACGXWR_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HFK0803684.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            complement(7462..8796)
                     /gene="rpoN"
                     /locus_tag="ACGXWR_002156"
     CDS             complement(7462..8796)
                     /gene="rpoN"
                     /locus_tag="ACGXWR_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HFK0803685.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            8856..8927
                     /locus_tag="ACGXWR_002157"
     tRNA            8856..8927
                     /locus_tag="ACGXWR_002157"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8889..8891,aa:Arg,seq:ccg)
     gene            complement(9119..10003)
                     /locus_tag="ACGXWR_002158"
     CDS             complement(9119..10003)
                     /locus_tag="ACGXWR_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFK0803686.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNYTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(10090..10989)
                     /locus_tag="ACGXWR_002159"
     CDS             complement(10090..10989)
                     /locus_tag="ACGXWR_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsiV family protein"
                     /protein_id="HFK0803687.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            complement(11006..11512)
                     /locus_tag="ACGXWR_002160"
     CDS             complement(11006..11512)
                     /locus_tag="ACGXWR_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFK0803688.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            complement(11701..12321)
                     /gene="rpoE"
                     /locus_tag="ACGXWR_002161"
     CDS             complement(11701..12321)
                     /gene="rpoE"
                     /locus_tag="ACGXWR_002161"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HFK0803689.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            complement(12397..12834)
                     /locus_tag="ACGXWR_002162"
     CDS             complement(12397..12834)
                     /locus_tag="ACGXWR_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HFK0803690.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTGGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            12997..13827
                     /locus_tag="ACGXWR_002163"
     CDS             12997..13827
                     /locus_tag="ACGXWR_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HFK0803691.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            13811..15178
                     /locus_tag="ACGXWR_002164"
     CDS             13811..15178
                     /locus_tag="ACGXWR_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFK0803692.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            15197..>15993
                     /gene="yidA"
                     /locus_tag="ACGXWR_002165"
     CDS             15197..>15993
                     /gene="yidA"
                     /locus_tag="ACGXWR_002165"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HFK0803693.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIK"
BASE COUNT         4328 a         3341 c         2948 g         5376 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgtttatta
       61 aaaaaatctt acgctaagta ggataaaata attccttgat atttttcgat catatccaaa
      121 taattatcga tttcaacata ctcatctact tgatgaggca aagtaacgac accaggccca
      181 aagacgacaa agtcgaagga atggttagct ttcgtaaatt cggctgcatc cgttgttgct
      241 gccgctccaa ctaaaggtaa tggctggctg aattgttgct gaatgcaatg aatcaaagga
      301 gaatctggat cagctttgac aggtattttg ttgtaatcga tcatcaattc caaatgatag
      361 tctgtctctt gattcaattc attgacgatt gattgcagca atgcaatgat tttatcattt
      421 gggtattctg gaatcgatcg aatgttccct tggagctgcg catggcttgg gatgctgttg
      481 acttgattcc cgccactgat caatgtaaca ttatggattg tttttcctag gacaggattc
      541 tcgattgttt cagcgaggtg attcatttca gcatttgctt tcgtaatgaa ttcatttagg
      601 tgattgattg cattataacc ttggtctggc atagagctat gcgcttcttt tccgtgcgag
      661 gtgactgtat agttgattga tcccatgtgc gtatacatca aactgtaatt ggttggctct
      721 ccgatgatca aggcatctaa gtcatctaca tagcctgctt tcgtgagctg ttccccacct
      781 agttcaccca cttcttctcc gacagtggct aataatttga ctgttccgtt aaatggtttt
      841 cctgactctt tcagttcgat catggcaatc accattgctg ccaagccact cttcatatct
      901 gtagcaccac gtccgtacaa acggttccca tggatttctg ctgcaaaggg tgcataggtc
      961 caagacgatt catcaccagc cgccacgaca tccatatgtc cagataggcc taacactttt
     1021 cctgattggc ccttttggta acgagcaatc aaattatctc taccatctct gtaagaaaca
     1081 atctctcctg ttatgtcatg ctttgccaaa agcttattca aataggctgc tacttcacct
     1141 tcgtttccat tcactgattt aattcggata atctcttgta aaatcgcgat tttttcttct
     1201 tttttcatct aatcctctcc cttgccattt ctttttattg tatttgagtg tgctcgaatt
     1261 ttcaaatagg agcaaccaaa gtaaaaatga agaaagagag ccactttatg aaaaatatgc
     1321 tgctacttcc ctcctatttt atttatacga gaggacttgc ccatagattc ctattctact
     1381 gttctatcct taaaagctct tatatgatgc tagttattgt tagctttcct ttttcaagga
     1441 tgatcttttc ttgtaccatt ctttgtaaac atcatataca gaagctagtt gcaaaaaaac
     1501 tctctacctg ctgatatttc agcaagtaga gagttcgatt acttaactaa gtgatcatac
     1561 tcgactatct ttcaatagtc gatcatgtat cttcattaga aaagaattat ttgtttttta
     1621 agttgtagaa agatttcaaa cctttgtatt ctgcaacttc accaagttgg tcttcgatac
     1681 gtagtaattg gttgtattta gcaatacggt cagtacgtga tagagaacca gttttgattt
     1741 ggccagcgtt tgttgcaaca gcgatatcag agattgttga atcttctgtt tcaccagaac
     1801 ggtgagatac aactgctgtg tagccagctt ctttagccat ttcgatagct tcgaaagttt
     1861 ctgttaatgt accgatttgg ttcactttga taaggattga gttagcaatt cctttttcga
     1921 taccttcaga taatttttga gtgtttgtta cgaacaagtc gtcaccaact aattgaactt
     1981 tgtcgcctaa tacgtcagtt aatttcttga atccgtccca gtcgttttcg tctaatccat
     2041 cttcgattga gatgattgga tatttagaaa ctaattcttc gtagaatttg atcatttcgt
     2101 cagttgtttt ttcgccttcg cctgagtcag ctagtacgta aacacctttt tctttgtcgt
     2161 agaattctga agaagcagca tccatagcaa gaacaacgtc tttaccaggt acatagccag
     2221 ctttttcgat tgcttcgatg attacttcaa aaccttcttc gtttgaacca aggtttggag
     2281 caaatccacc ttcgtcacca acagaagttg ctaatccgcg agctttcaag attgaagcta
     2341 atgcgtggaa tacttcagca cccatacgta gagcttcttt gaatgttgga gcgccaacag
     2401 gcatgatcat gaattcttgg aagtcgattg agttatcagc atgtgatccg ccgttgatga
     2461 tgttcatcat tggtgttggc aatacttttg tgttgaatcc gcctaggtag tggtataaag
     2521 gtacttctag gtagtcagca gctgcacgtg caacagcgat agaaacacct aaaatagcgt
     2581 tcgcacctaa tttacctttg ttaggagttc cgtctaaagc gatcatagct ttgtcgatag
     2641 ccatttggtc acgaacatcg tagccaatga ttgcttcagc aatgatgttg tttacgttgt
     2701 cgacagcttt agttacacct ttaccgccat aacgagcttt gtctccgtca cgtaattcaa
     2761 ctgcttcgta ttcaccagtt gaagcacctg aaggaaccat tccgcggcca aaagctccgc
     2821 tttctgtgta tacttctact tcgattgttg ggttaccacg tgagtctaag atctcgcgag
     2881 cgtaaacatc agtaataatt gacatgtttt gtctctcctt tgagtttgtt ttttcctaag
     2941 ggatttccct catatacgat tttagttaat tttgctcatt agtgcaaaca tttcttgcat
     3001 ttttcgcaaa ttttcaacaa ttattttaca gcgtctaaca atgacaagaa tgaatctgct
     3061 tgcaagcttg cgccaccgac taaagcaccg tcaacatttt cttttgccat gtattcagca
     3121 atattttctg gttttacaga accgccgtat tggatacgaa ctgcttctga tacttctttt
     3181 ccataaagtt tttcaactgt ttgacgtaca actccacaaa tttcgtcagc gatttgtgcg
     3241 tcagctgatt taccagtacc gattgcccag attggttcat aagcaataac catgtttgac
     3301 acctgttcag ctgaaagatc agctaaacca gctgtaattt gtccttcgat ccattcagca
     3361 gttttgcctg cttcataggt ttctaaagat tcgccgcagc ataggattgg tgtcatacca
     3421 tttgcaaaga tagctttcgc ttttttattg atgtcttcgt ctgtttcatg gaaatattca
     3481 cgacgttctg aatgtccgat gatcacataa tgaacaccta gatcagcaag agctgctggt
     3541 gaagtttcac cagtgaacgc acctgagttt tcccagtagc agttttgtgc tgagattttt
     3601 agttctgtac cttcagctga tgtcattaat tcttgtaaga ataatgcagg agatccgatg
     3661 actgaatcaa ctttgtcatt tgaagggatt ttgtttttta ctgcttcagc aaattctttt
     3721 gcttctgatg cagttttgtt cattttccag ttacctgcga taataggttt acgcattgag
     3781 gaacacactc cttaatttat tgaaaaatgg ctagggagtc atgaaaactc ccttcacctt
     3841 ttgttcgatt actcgtcaga attgagcaaa cttggtcgtt tatttatcgt tgattgctgc
     3901 tagtcctggt aattctttac cttcaagcaa ttccaagctt gcgccgccac ctgttgagat
     3961 gtgtgtgaat ttgtcagcaa atcctaattg ttctgctgct gcggctgagt ctccgccacc
     4021 gatgattgtt gttgcgcctt ctaagttagc gattgcttca caaacaccga ttgtaccttt
     4081 agcaaagtta ctcatttcaa atacacccat aggtccgttc caaacaactg tttttgcacc
     4141 ttgtaatgta tcagcaaata attttactga tgctgggccg atgtctaaag ccatcaaacc
     4201 atcaggaatg tctccttcga ttacttgtgt ttcaacatca tttgaaaatt ctggtgcaca
     4261 gacattgtcg attggcaaga caagtttgtc gcctgctttt tcgattaatt cttttgctag
     4321 ttccacttta tcagcttcta ctagagagtt accgatcttg attccttttg cttcgtagaa
     4381 tgtgtaagtc attccgccac cgatcaagat tttatctgct ttaggaatca agttttcgat
     4441 tacgccgatt ttatcagaaa cttttgcgcc accaaggatt gcaatcattg gtcgttttgg
     4501 ttcttctact gcttcaccga tgaacttgat ttctttttcc atcaagaatc cagcaactgt
     4561 tgggatacca gttgaagcga tacctacgtt agaagcatgt gcacggtgag ctgtaccgaa
     4621 agcatcgtta acaaatacat cgcctaatga agcccagtat ttacctagtt ctgtatcatt
     4681 tttgctttct tttttaccgt caatatcttc aaatcgtgta ttttcgaata cgacaacgtc
     4741 gccgtcattc atgttgcgga ttgcttcttc taattgttct ccgcgagttt caggtacgaa
     4801 tgttacttct ttacctaata attcgcctag acgttttgca actggagcta aagattttcc
     4861 ttctttatct tcttctgttt ttacacgtcc aaggtgagag aaaaggattg cttttccgcc
     4921 ttgttctaga acgtagttga ttgttggcaa tgctgctttg atacgagtgt cgtcagtgat
     4981 cacgccgtct ttcaaaggaa cgttgaagtc aacacggaca agaacttttt tgtcttttaa
     5041 atcgatatct ttcactgttt tcttagccat tttatttcct cctgaataaa cttattatca
     5101 aaaaaagcgg aagaagcgcg attgcttccc cgcttttaaa tgtacatgtc tataatttac
     5161 acttgtacgt ttgtctatct tataagttag cgaagtattc taaagtacgt actaattgtg
     5221 cagtgtatga catttcgttg tcgtaccaag caacagtttt aactaattgt ttgtcgccaa
     5281 ctgtcattac tttagtttgt gtagcatcaa ataatgaacc gtaagtcata ccaacgatat
     5341 ctgaagaaac gatttcgtct gtgttgtatc cgtaagattc gtttgaagct tctttcattg
     5401 ctgcattgat ttcgtcaaca gttacttctt tttcaagaac tgttactaat tctgttaatg
     5461 aacctgttgg tacaggaaca cgttgagcag ctccgtctaa tttaccgttc aattcgggaa
     5521 ttactaaacc gatagcttta gcagcacctg ttgagttagg aacgatgttt gcagcagcag
     5581 cgcgtgcacg gcggaagtca cctttaggat gaggtccgtc tagagtcatt tggtcacctg
     5641 tgtaagcgtg gatagttgtc attaatcctt caacaacacc aaatttgtcg ttcaatgttt
     5701 tagccatagg agctaaacag ttagtagtac atgaagcacc tgagataact gtttctttac
     5761 cagttaatgt ttcgtggttt gtgttataaa cgattgttgg aacatcgttt ccgccaggag
     5821 cagagataac aacgcgttta gcaccagctg ttaaatgttt ttcagctgct gatttagaag
     5881 tgaagaaacc agtacattct agaacgatat ctacgcctag ttcgccccat ggtaattctt
     5941 ctgggttgcg gttagctaat actttaactt cttttccgtt tacgttgaat gaaccttcat
     6001 gaacttcaac tgttccgttg aaacgtcctt gagttgtgtc gtattttaac aagtgtgcca
     6061 acattttagc atctgtcaag tcgttgattg ctactacttc gattccatct acatcttgga
     6121 tacgacggaa tgctagacgt ccaatacgtc caaaaccatt aatacctact ttaactgtca
     6181 tttaagattt cctccttatg aaaatcaaaa aaatatttat tttaaagggt tacccctttt
     6241 aaaatctcat ttgcagcagc ttcatcagtg atgagccacg tttgttttgg tgcatttttc
     6301 atataagctc gaattgcttt agcttttgat tttccgcccg cgattgccat gatgatcggg
     6361 actttttcca aatcttgcaa ttctatgccg attctaggga ccttataaac gacttcacct
     6421 ttttcattga aaaagtagcc aaaagattcc gcaacagcat ttgcttgttt cagcatgact
     6481 aattcttttt cagtcatctt acgacgtgct gccatgtgta atgcacgccc aatactatga
     6541 ataacacaat tcgcttcact aatcaagttt aagacttctt ggatagatgg ctcattgagt
     6601 aaagaattgt aagttgccag acttaattgt tccggaacat aaagtgcgcg gtggttaccg
     6661 tttgctttag cagccattct tgcactgaca gaatttgcct gtacagttat cgcttcacca
     6721 atcccgcctc ttgcagggac aaacaggtta tgccgtttct tattttccag attagacaat
     6781 tgttcggcta ccacagccat agtagttcct cccatcacag cgatgatatt ctcgccttct
     6841 ggaagtagtc ggtctaaggc ttcgctcagc gcttcgccga atgcatcagc cactttggtc
     6901 tgctcttcgc tgtttcctga aacaacgata cagcgttggt taccaaaata ttctgccaac
     6961 tgttgttcgg tttgatgcgt acctaaaagc tgatccatga agttttcaag gctttgataa
     7021 acttcttcgc ccttagttgt cagcgtcata ccgctttttg aggtgtcgat caaattcaga
     7081 tttttcaaaa ggtctgtttc tgttcgtaag actcgttctg tgatccccat actttccgat
     7141 aaacttcgac gcccaatcgg ctgcatccaa tagatatttc gtaaaatttt atagcgttct
     7201 tgcaacactt cgataatatc tggtgcaaca gattcaatca tttttatttc atccagcata
     7261 gcgatctcct tagttggaca ctttacgtcc aatgtagact taaaacgacc catatacgat
     7321 aaaaaaagaa attaactatt cgaatttcac atcaataaag ggaaatctca acctcacgac
     7381 tgtaagtcta acagtttcgc tctcgttttt caactaaaaa gactagaaaa agtgaaatac
     7441 tttttctagt cttttgactg attagttatc ataacgtttt ctttttgatg aactcgggat
     7501 tcctaataaa tcacgatatt ttgctactgt tcgtcttgag atcgctatct catctttttt
     7561 cagcaattca accaatttct ggtccgacaa cggcttgttt ttgtcttctt gatcgactaa
     7621 ttcctgcagc tttttcttcg ctgtatctgc tgaaaggtct tctgtctgtt ctgtactatt
     7681 cgtaggaatt cgtgtagtga aaaatttttt taattcaaat acaccgaaat ctgtttccaa
     7741 atatttcccg ttgactgcac gactgaccgt ggattcatgc acatctatct cagttgcaac
     7801 ttcctttaac gtaagaggct tgattggacg ttccttgtcg ataaagaaag ctttttgccg
     7861 ggaaacaatg acttgagcaa cccgcaaaat tgtatcccca cgttgtagga tcgttttctt
     7921 caaccattcg aattcctgtt tccgttcttt taaataattt tcagtttctt tatctgcttg
     7981 ttgtgacatt tgtttgaagt aactctcttg aaagcgtata tttggctgat tttttcggtt
     8041 tgagataact tgtacatttt tatcgtcgtc cactaatacc cggacatcag gaataatgta
     8101 caattcgctg ctacggtcga aaatccggcc agggcttgga ctcaacgttt gtaaatagtc
     8161 gaatatctgc tgaacagcat gtagatcaac agaaaaacgt tgtgcgattt ctttccattt
     8221 tcgctccacc agttcctcaa aacattcttc caacacgata taagctaatt ccggcgcata
     8281 atcatctcgt tctgtttgaa gcatgagaca ttcttgcaaa ctacgtgcac ctactccagc
     8341 tggttctaat tgctgaatca gagtcaacgc atcgagcatt tggataggcg tagctccaat
     8401 ctcttttccg gcttcttcta aactaatcgt caaaaatccg ttcaaatcga tgtattctac
     8461 aagataaaga acgattttcc tcaaaaaagt atctcggtaa ttcaaatgga cttgttcgat
     8521 caatgaatca aataaagacc cttttgtatc aggaatctga tttaggtaat ttgtctcttc
     8581 tccttcataa gaagatgaag aagcttttat gtaatctggc tgccattccg gctcaacaac
     8641 ttccaccaat ggattttcca ttgcttgatt ctcaacgaat gccaacagct cctcactgtt
     8701 atattgtaaa acttggatgg actgttgcaa ctgttgcgtc atggctagtt tctgtgtctg
     8761 ctgctgtttt tgtgaaaaat tttgctcaaa tttcattttt ttgtccaatc cccttgtaat
     8821 tttttatctg tttagttaca attatcccag tgcttgcgtc cttagtgtag tggatatcac
     8881 gtaagattcc ggttcttgag acgggggttc gattccctca ggacgcgttc tactgctatt
     8941 ttagcataat ttacgaatag ttgcttcttt atttttaagt gaaaactgtc cgccaaagaa
     9001 aattggtgga cagttttttg ttgtacctgt atagatattg ttaagccttt gcaagtaagg
     9061 tagttatgtg ttcaactact tattaaaatg tgttatttat taaagatact tgtctcactt
     9121 actgaactgg ccgatgatcg tttctgccat aatagttctc gacagccgtt ggatgcccta
     9181 ataaatcccc aactgtcgtg atgcgatacc cttgctcttt cagataatcg atcacttgag
     9241 gaacggcacg aatcgtttca ggatagatat catggaataa aataattgcc ccatcgtata
     9301 ctgttgcttg gatcttctgc aaaatcaaat caggatttct tgtcttccaa tcttctgaat
     9361 caacagacca ttcgatgatc ggtcgctgga tgatcgttgc tcctacattc gtgacagaac
     9421 catagggcgg acgaacaaaa gtgggggttt tgccagtgac ttttttgatc tcagtgtctg
     9481 ctttcgtcac ttcctccgtc atcgactggg cagaaagagt ggccagattc tgatgatcgt
     9541 atgtgtaatt gccaatctcg tgccctgctt cagctgtctg cttcacgatt tcaggatgct
     9601 gcgccgtatt ttctcctaag acgaaaaaag tggcatgcac gtttttttct tttaagattc
     9661 gcagaagctg cggtgttgtg gtcgctcctg gtccatcatc aaagctgatt gcgacgcttt
     9721 tgacagccgg atctcggctc gtttttgtac tgtcttgtgt tgattgtgat gactgacttt
     9781 gtaccttttc cgctgattct tgaatggctt ctttgacgtt agctgtttca gttgattggc
     9841 ttttaatggt tgattgttct gattgtttga aagattgtga cgaatgctcc gaagagtgtg
     9901 tttgtccttt tacttcggtg atcaaggagg ccaccgaagt aatttcgaaa aacaaaagca
     9961 cggataaagc aataatactg ataactaaat aatttctttt cactatatct cttctttctc
    10021 tttttctctt cttattattt acttgtactt acttgaaaat tgaaactgct agtcgcaact
    10081 acttctcgtc taatgatcca aataatcttc cgatgccaaa atcgtttttg tcacggactt
    10141 aggaatgaca aattctggtg tacccatata accaggagca atttcgtatt gagaaaaagt
    10201 caaaactaat tgatgctctt tgttcaaata aaaacttcgt gtaggcgtaa caagtgttgg
    10261 tttttctatc gtcccttctt gaatatcttg ctcagtccaa tagtacttag atggatcttc
    10321 cttgacttgt tcggccatct gccgtttgac ttcttttgtc aaaacagata gataggtgtc
    10381 atctttgaat aaaagtggaa gtgagagctg gacactgttt ttcttgtcga ttgtgtcgta
    10441 tcttttttca acatggctat ctgctgctgt ttgggtgatc tgcctttcaa tcacgagaaa
    10501 ccggttatcg tctacgattt tctgataatc tcccaaaact tggtaatgat ccgtttcaaa
    10561 atttccatat tctttttcag ctttttcaaa atctgcttgt ccttcgcgaa agtatttttg
    10621 atttaatcca tgaattgttt tattttcttt ctcattttgt gtattgatct tcggtacctg
    10681 aatatcgatt ttttcagatc gatcagtaaa gcgttcgcct aagatcaatt caatgactga
    10741 tcctaagatg ggtaaatctt ctgcaaagct tcgaacttga ctattaaaaa gaaggctact
    10801 tgttgtaatc attacgatag ccaaagatac tccgaaccct tggagacgtc tctttctccg
    10861 ctttgctttt ataaatgatt gctcttcgat aataaaacgc tggcggatct cctctttaag
    10921 ccctttggga attgcttgtt ctttataagt tttctttagt ttttttaaat tttctttttg
    10981 ggaatacatg gcactcttct ctccttcatt ctaggatttg acgtaaagca ttcaatgagc
    11041 ggtacatttt cgttttaact gtgttttcat tcatatccaa gatagtcgca atttctttca
    11101 aacgaaatcc ttcaaaaaag tagaggatca gaatctcttt ttccggactg tctattttat
    11161 ctaaaatcat atggagctct gcaacggaag tttctaaagg taactgttgg gggatatctt
    11221 gaatttcaaa taagtccaca ggcgtccttt tttgtctgcg ccaactatct aatgccgtgc
    11281 ggatcaatat ccgataaaac catgcactaa aatgctcgat ctctttttct ttttcaaaat
    11341 agttcagggc tttatgaaaa ctatcttgca tcacatctaa ggcctcttct ttatcatgta
    11401 cgtaattcat cgtgatacgg aacatttttt gataatcagt ttcgatgagt ccattcagca
    11461 ggtgacggta tttttcgatc tgccgttttt tcttatatcc agtaaaaatc attctccact
    11521 cctttctgcc tcacttaata tgacgtacaa ggtgcgctaa aagtttcaat ttttttattt
    11581 tttatgtatt tacttgggat ttttatatac aaaaaagaag gtgtgacaaa aatcgtgtca
    11641 cacctcctta ttctgatagg ctgatcgtct ctgtcacaac ctctcgtaag aaaataatgt
    11701 ttattctttt tcagagtcag aaaattcttc ctcttcataa tcttcatcat catcgtcttc
    11761 gtctatgata cttaaatctt cttcgatatt tcctggcaag tcttcttcat catctgtcgg
    11821 gtcatctgct ccgatttctt gcaagtcaga attataagca gcgatttctt catcttcatc
    11881 atcatcgtca tcaaacagat catcgtcatc ttcttctgtc agatctgtat cttctgggtc
    11941 atcgtcattg taatcgatcg cgtcttcatc atcattgata aaggcgttga ctttcttgcg
    12001 tttacggcga cgtggagtat cttcatcctc ttcgtccatt ccatggttta cttcttcatc
    12061 gatcgaatcg atagcatacc atgaacgcaa gccccaacga ttatccccta atgagataaa
    12121 gctgccgtca atattcaagt cagtataaaa ttgtgcgagt gaatcacgaa tttcactgtc
    12181 tgatttccca agatagtttt ggatctggtt agctaaatca gaaaaatcca tgacatcgcc
    12241 acgttgttct aagatcgcgt gtgctacttc gatcattgat aattcgcttt tgtttgcacc
    12301 ttcaaataca ctaatttcca atcaggacac gtcctttcac agtctactcc ttatcataca
    12361 aaatcagaca caaaaaatca aacttttctt ttatatttac gctgtaaaat ccaaggtcaa
    12421 ataatattcg ccgatttttt ccggtcccat gaacagatca taatcgattc gaaccttccc
    12481 tcctgtggga cggtctttca aactaacatg cagttctttc gtaaaagtag caatctggat
    12541 cataccgtat ggtgttcgat aggatgtttc taaccgttct ttatagccaa atttcaaacg
    12601 catccgcatt tctcctgcac ggatcagctg tacatgacca tctggaacta atttgatcgt
    12661 tacaggaatc tcatcgcccg tctcctcctg aatctcttta taacgtatgt acagcgtatc
    12721 gccaattgtc accatttgcc ctttcaaatc aaaataaaaa tcttgcactt ccccttgctg
    12781 ttttactttt gtacgcaatt tgattgaaat cggtgttcct tgtgataatt ccattattca
    12841 ttctccttta cttctcatag ctacattgtt cctagtttct tttgttttgt caaccaactt
    12901 gtccattttt acagaaaacc ttttttccaa aacaactctt tgattttaga gtataatatt
    12961 gtagaaaata tgaatttata caaaggagcc ggttgaatga accctgcgat tcgactagat
    13021 cagcacattt atcaaaaaaa cgacttttcc ccttttgcat taacagatat attaacggaa
    13081 tattctaaag aacaccagca aatcttttta catttctggc aatatgactg cacagtcatc
    13141 ttaggtatga aggatgttcg aactcctttt ctaagtgacg ggatccaaac actgaaagat
    13201 gcaggttacg ctccagtgat cagaaattca ggtggattag ggatcgtatc agatgaagga
    13261 attttgaata tttctttgat tttcccccaa agtgacacaa aaaaaataac catagatgac
    13321 gcttacgagc aaatgctcct attgactaaa tacgcttttc caaaggcacc gatacaagca
    13381 ttcgaaatca cccattctta ttgtcctgga acttatgatt taagcatcca tggcaaaaaa
    13441 tttgccggta tcgctcagcg tcggatcaaa aatgggattt ctgttatgat gtacttaagt
    13501 gtcaacggta atcaggaaaa acgcgggcaa gtcatgaagc gattttatca atctgcttta
    13561 aaagaagact ttggtacaaa tggctatcct gcagtggatc ctgctacaat ggcaacactt
    13621 gaagaactgc ttgaccaacc cctttttgta aaagaagtca aagaagcatt tgcaaaagct
    13681 tttgaaaagc tgtattctgc aagtgattta caggattcta ccgactggct aaaaaaagaa
    13741 atccagctgg agcaatggaa caaccaaatc cagagaatgg aacaacgtaa taacataaag
    13801 gagctacatt atgacaaccc cttataaata tcaaatgctg cctatggaaa aagtttttcg
    13861 tgatccagtc cataactata tccatgtcca gcatcaagta atcttagatt tgatcaattc
    13921 gaaagaagtc caacgtctac gacgcattaa acaattaggc acttcttctt tcacttttca
    13981 cggagcagaa catagccgtt ttactcattc attaggcgtt tatgagattt caagacgaat
    14041 ctgcgatatc ttttctcgaa atttttcaaa agaaaaaata ggcaacggag gctgggatga
    14101 tcaggaacgg ctggtgactt tatgtgcggc actgttgcat gatgtcggtc atggtcctta
    14161 ctctcataca tttgaacata tcttccatac gaatcatgaa gccatcactg tagagatcat
    14221 cacttctcca gaaacagaag tgtatcagat tcttaaccga gtagaagaag gttttcctga
    14281 aaaggtagct agtgtgatcc aaaaaactta ccccaaccca caagttgtcc aaatgatttc
    14341 tagtcagatc gatgcagatc gaatggacta tttgcttcgg gatgcttatt tcactggaac
    14401 agaatatgga acatttgatc ttacccgaat attacgtgtg attcgtcctt atgaaggcgg
    14461 gatcgctttt tccatgagtg gcatgcatgc agtggaagat tatatcgtta gccgatatca
    14521 aatgtatgtg caagtgtact tccatcctgt ttcccgtggt atggaagtaa ttttggagca
    14581 tctgcttcat cgcgcacacg agttgtatca agaagatgcc agcagttttg aactccattc
    14641 tcaattactt ctgccatttc ttgacggaag ctttacttta gaagaatacc tcaaacttga
    14701 tgatggggtc ttgggcactt actttactca atggtctgaa tctgctgatc ctattttaaa
    14761 tgatttagct aaacgttttt tgaatcgtaa accactgaaa tctgctactt tttctggcaa
    14821 ccgggattca aaattagtcc aagaactcac tttgttagta gaaaaggtcg gatataatcc
    14881 tgtttattac actgctgtga attctagcta cgatctacct tatgattttt atcgcccaga
    14941 acaaggcaga catcgcacac aaatcgagat tttgcgaaat gacggaactt tgatagaatt
    15001 atcacaggtt agtcagcttg ttgctgcatt agcgggacaa gaacaaggag atgagcgatt
    15061 tttctttcca aaagaaatgg ttgatccgtc cttgcgtgat cattatgatt tatttgacga
    15121 aacttatcaa gaatttgcca gccatatccg taatggcgca ttgattgaaa taaattaaaa
    15181 tatattggag gaaattatgt ctatcaaact agtcgctatc gacatcgatg gtactttatt
    15241 aaatgagaaa agagaagtaa caaaagaagt aaaagaagcg attgccgctg ctgttgcaaa
    15301 aggtgtttcg atcgttttat gcactggccg tcccttacca ggtgtccagg aacagttaaa
    15361 cgagttgaac ctttttcaag ataatgatta cgttattact tataacgggg cactcgtaca
    15421 acaaacgaaa tcaggtaaaa tcatcgcccg tcacggactg acacatgaag atttcctaga
    15481 gatcgaagtg atggcacgcc gtgtcggcag tcatctccat tcgatcgatg acaaagcgat
    15541 ctacacgcct aatcgagata tcagcgctta tacgatccac gaagcaagtt tagtcaagat
    15601 gccgctaaaa tatcgaacac ctgaagaaat gacaccagac atgaacatcg tcaaaatgat
    15661 gatgatcgac gaaccagaaa ttttagatgc agcaattgcg cgtttaccgc aaactttccg
    15721 tgataaatac acaacggtca aaagtgcgcc ctattacttc gaagtactaa ataaagaagc
    15781 aagtaaaggt gcggcagttg cgaatctcgc acagcacctt ggtattgatc aagatgaaat
    15841 catggctatc ggagataacg agaacgactt atccatgatt gaatatgctg gtctaggagt
    15901 agcaatggga aatgccgttt ctcttgtcaa agaagcagca aatgtcatca cttcatcaaa
    15961 cgacgagcac ggtgtagctg aagcaatcaa aaa
//
LOCUS       DAYNVV010000058        15934 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.061, whole genome shotgun sequence.
ACCESSION   DAYNVV010000058 DAYNVV010000000
VERSION     DAYNVV010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15934
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.061"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(11..886)
                     /locus_tag="ACGXWR_002166"
     CDS             complement(11..886)
                     /locus_tag="ACGXWR_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFK0803694.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            1034..1366
                     /locus_tag="ACGXWR_002167"
     CDS             1034..1366
                     /locus_tag="ACGXWR_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFK0803695.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            1478..2686
                     /locus_tag="ACGXWR_002168"
     CDS             1478..2686
                     /locus_tag="ACGXWR_002168"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HFK0803696.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            2840..3295
                     /locus_tag="ACGXWR_002169"
     CDS             2840..3295
                     /locus_tag="ACGXWR_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803697.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            3657..3932
                     /locus_tag="ACGXWR_002170"
     CDS             3657..3932
                     /locus_tag="ACGXWR_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803698.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            3945..6023
                     /locus_tag="ACGXWR_002171"
     CDS             3945..6023
                     /locus_tag="ACGXWR_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFK0803699.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            6186..8069
                     /locus_tag="ACGXWR_002172"
     CDS             6186..8069
                     /locus_tag="ACGXWR_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFK0803700.1"
                     /translation="MKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKTS
                     LLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVRA
                     YEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIST
                     LSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDRY
                     FLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMRA
                     GVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRINDQ
                     TLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQE
                     NEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEKR
                     RLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVAD
                     KLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEW
                     ETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEW
                     VED"
     gene            8081..9028
                     /locus_tag="ACGXWR_002173"
     CDS             8081..9028
                     /locus_tag="ACGXWR_002173"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFK0803701.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            9048..9575
                     /locus_tag="ACGXWR_002174"
     CDS             9048..9575
                     /locus_tag="ACGXWR_002174"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFK0803702.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(9638..10291)
                     /locus_tag="ACGXWR_002175"
     CDS             complement(9638..10291)
                     /locus_tag="ACGXWR_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HFK0803703.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            10423..11265
                     /locus_tag="ACGXWR_002176"
     CDS             10423..11265
                     /locus_tag="ACGXWR_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFK0803704.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            11423..12319
                     /locus_tag="ACGXWR_002177"
     CDS             11423..12319
                     /locus_tag="ACGXWR_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFK0803705.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            12322..13035
                     /locus_tag="ACGXWR_002178"
     CDS             12322..13035
                     /locus_tag="ACGXWR_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HFK0803706.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            13055..13573
                     /gene="msrA"
                     /locus_tag="ACGXWR_002179"
     CDS             13055..13573
                     /gene="msrA"
                     /locus_tag="ACGXWR_002179"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFK0803707.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            13570..13797
                     /locus_tag="ACGXWR_002180"
     CDS             13570..13797
                     /locus_tag="ACGXWR_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HFK0803708.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            13949..14500
                     /gene="lepB"
                     /locus_tag="ACGXWR_002181"
     CDS             13949..14500
                     /gene="lepB"
                     /locus_tag="ACGXWR_002181"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFK0803709.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(14583..15125)
                     /locus_tag="ACGXWR_002182"
     CDS             complement(14583..15125)
                     /locus_tag="ACGXWR_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFK0803710.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(15362..15760)
                     /locus_tag="ACGXWR_002183"
     CDS             complement(15362..15760)
                     /locus_tag="ACGXWR_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFK0803711.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
BASE COUNT         5520 a         2740 c         3211 g         4463 t
ORIGIN      
        1 gtcttttttc ttatagtttt ttcagtaatc ttgtctgtgg cttcaaataa gtaaagcctt
       61 gcccttccac ttcatgcaca ttgatgattg aaaggaaagc tttttcgtca atctcgtgga
      121 cgatcctctt agcttcagtt aattcactag agctaacgac catatagatg attttttttg
      181 aattaccaga gaatgcgcct tctccagaaa ggaaagtcac acctctttgc agaccggtca
      241 tcagtagtgg tgcaatctct tcgcttttgt tggagacgac aagtagacct tttgcagaat
      301 atccgccatc taagatcgaa tcaatcacac gactgaaaac atacgaaaca atcaacgtat
      361 acatcatacg tttcaagtcg atataggtta atgaagcaag taagacgatg atatcaaatg
      421 ccaataggga acgccccata gtgatgccgt aattttgttc taaaatccga gcgataatat
      481 cactgccgcc tgttgttcca cccatgcggt agacgatccc gcttcctaca cctgcaacta
      541 aacccgcaag tagagaaacg atcagtagat catgctgtaa attgatttct agtggaaccc
      601 tttgccagat ccataaaaag aatgacaaag aaagtgtacc tagaacagta taggccaagg
      661 aacgtttacc gaggatcttt cctcctagta aaatcaatgg gatgttgatt aataaagtcg
      721 tataagctgg atcaatacca aataaagctc ttaagatcaa ggtgatccct gagactcccc
      781 cttctgctaa atgattagcg atgttcaagt aaacaagacc aaatgcataa atacttgttc
      841 ctataatgat aaaaagaact tcttttactg tttttcgttt gaccatatga attccagctt
      901 tcaattatgt attttcacag aatttccatt tagaaattcc ttcctaaatg tagcatggaa
      961 attcgatttt ctcaattgct cttatctagg atttgcgtta aagttttggt aagatagttt
     1021 tggagggaaa aagatggata aaaagcgttc tttatacagt atgcagcagg aagtggatga
     1081 atatatccag caattcaagg tggggtattt ctctccatta gctcagatgg ctcgattaac
     1141 tgaagaagta ggtgaattgg caagagaagt caaccacact tatggagaaa aaagcaaaaa
     1201 ggcttctgaa ccagttaact cggtagcaga agaacttggt gatgttttat tcgttacgat
     1261 gatcatggct aattcattga atatcgactt aactgaagtt tttgaaaaaa acatggaaaa
     1321 attcaatcaa agagaccata atcgctttga gcgtaaggac gagtaaacaa gatgaagtgg
     1381 tcctggcctt gaagactctg aaacggactt gtcaaacagt caccatgcaa ctgagtcttt
     1441 atctcaggac aagaaacacg caggaaaggt tggaaaaatg aaattaaaac aattacctct
     1501 ggaataccaa aaggcaattc cagttctgaa aaaattagag aatgcaggat atgaagctta
     1561 ttttgtaggt ggaagtgttc gtgatatctt gctgaaccag ccaatccatg atgtggatat
     1621 cgcaacaagc gcatttccag aagaaatcaa acagcttttt ccaaaaacga tagatattgg
     1681 gatcgaacat ggaactgtgt tggtattaga aaatgatgaa caatatgaga tcaccacatt
     1741 tcggacggaa tcaacttatc aggactaccg tagaccagat catgtcgaat tcgttcgttc
     1801 gttggcagaa gatttgaaaa gaagagattt tacgatcaat gcgtttgctt tgaaagaaga
     1861 tggagaaatc atcgatttgt tcgatggtct gcaagatcta gaagaacaga tcttgcgagc
     1921 tgtaggcaat cctcatgagc ggttccatga agatgcctta cgaatgatgc gcgggttgcg
     1981 ttttgtcagt caactagggt tcaaattaga ggaagaaacc ttctacgcca tcaaagaaaa
     2041 ccacgagcta ttaggtaaaa tatctgtaga acgtataaat gtggaattca tcaagatgct
     2101 cttgggaaat gaacgggccg cgggaatcca tgcatttatt gaaacagagt gctacatttg
     2161 ctgtcccggt ttgaaagaag aaggcgaagc acttttacgt tttgctgaat taccatccgt
     2221 cccattgaaa gaagagagcc aagcatgggc attattgatc agccaactgg atctaaaaga
     2281 aaatgagatt cgttcctttt tgaaatcgtg gaagtgttct aaccaaatga ttaaagacgt
     2341 tcaagcactt gtccaaggac tacgacaacg agaaactgga gctttggaac cattcgaatt
     2401 gtacttctta ggcaaaaaac atgcactgca agtagaagaa ttgatgatct attttgacga
     2461 aacacctcag atggatgccg taggagaatc ctatgatcgt ttacctatca agtcattaag
     2521 cgaattagca gtagatggta aaatcttgct agaagaaact ggaaaaaaac ctggtaagtg
     2581 ggttagtgaa gctttgcaat tagctgaaaa agccgtcgta gaacaaagaa taaaaaatga
     2641 taaaaaacag gttttggatt ttttatcgaa agaaaaattg atttaaaaaa cactagactg
     2701 tatctgctca gctttgttgg ctacttaaag tgggcagata cgtcattaga agaaaaaaca
     2761 taagatgtga ccacttacat aaatttgtgc taaactgagg tagtacaaga ataaattaca
     2821 tcataaagga gtctttttaa tgagtaaaga aatgacagcg ctaaaatttt attttagaaa
     2881 tggagaaacc tggacgatca accgccgtca tatcggcgat ctttggatca aacaaatcac
     2941 aacaagtttt ggacgaatca atggcagtga atttgttgaa atccatccgt gtgctggatt
     3001 taaaatcgaa atcttccatg aaggggacgc agttgcgaca catgatatca acctaggcgg
     3061 actggaaatg ggcatgttta atcgcgcatt gaaatacgaa gatatcgagc gaatggaaat
     3121 cctttaccga aatggcacac ctgatcttgt gtacttccca tatctagata aaggaacaga
     3181 aggattagac aatcaatatc aatcaacaaa aatcagcgaa aaaacaggta acttgtatat
     3241 cgtgatcaat ccagatcaac gtgtagaaga tgtatacggg gaatttttcg aataaatcga
     3301 tttttacgca aaaatgaggc tgtgaaagag atgtgtctta ttactactga taggctgtct
     3361 cttccacacc gtttattcag aataagggac tgtgacaaga tttttgtcgc agccccattt
     3421 ttttgttgtg ataaaagaac aagaaaggca ggaatgggaa agtaaacatc cttttgtcag
     3481 aaacttttat ctttcttaag ttttacttga tatctgatac tatttggaat agaatgaggc
     3541 gttgaaaaat ttatggaaat ttctaactag caataaacga tgaaacaatg aaatattttt
     3601 catccaaaaa gaactttgct ataatgatgg aagtttgtgt ataggagatc tggaaaatga
     3661 gagagagttt tgaacaacaa aaaaaactgt tgcatgatcg ctatggcgcc ctttcgatgg
     3721 atgaccgccg tcaaatactt tgtaagttgc gtaaaagaaa tatattgatg tatcgtcagt
     3781 tggaacgtct gaaacatgat ctgcttcgtt tggagtcaaa acgtgtacag tgtgaattag
     3841 aggggaacca aacacaggtt gaagtagtcg aaaccaaaat tttaaagaaa aaagaacaat
     3901 ttttaaaaat gcttacacaa aataaaaaat aaaggggatg gacgatggaa tttgctgagt
     3961 tagttattgt atttgcagta acgatcacct tatcgaacat agctagccgc attttgccaa
     4021 tgattccagc tccactgatc caaattttcc ttggagtggt attaggtctg acagagtggg
     4081 gacaatcaat cgattttgaa cctgaattgt tcttagttat gattattgca ccattgttat
     4141 ttagagaagg agaaaaagca gatatttctt cgattctcaa aaatttcggg acaattttgt
     4201 tcttggcatt tggaggagtc attttgaccc ttgtcggggt aggtgcgacg ttatcattcc
     4261 tgttgccaag tgtcccactt gctgcctgct ttgcttttgg agcagcgtta ggtccgacag
     4321 atgcggtagc agtcagttct ctttctggac gagtgaatat ccctaaaaag gcgatgcata
     4381 ttttggaagg agaaggtctt ttgaatgatg catctggtgt tactgccttc cagtttgctc
     4441 ttggtgcgct gatcaccgga tctttttcag cagtaaacgc ggggatgagt ctagtagttt
     4501 ctagtattgg gggagctttg atcggctttt tgcttgtctg gttcaaacaa aaaataattc
     4561 atttgatcga aaaagcatca gcacaagatg tcacagggta tctgctgatc gaacttttgc
     4621 ttccttttct agcctatgta ttggcagagg catttgatgt atctggaatc attgctgcag
     4681 tggcagcagg tattctccaa gcttctggtt ttaggaaaat ctctgtgttt gatgcagaat
     4741 tgtcgagctt gtcccacagt acatggacaa ctattgcttt tacactgaat gcattagtat
     4801 ttatattttt aggaatcgaa ttgacgcaag tgttctcgcc agtatgggga gacggtttat
     4861 atccaaacgg tcttttatta gcgattatcg tattaatctc tgtcatgctt tttgtgatca
     4921 gattcatttc tatcagtctt ttttatgtat tcaaagatgg cagtaaaaag ttcaaaaaac
     4981 agttgaacga gatcttgatc ttaacatttg gcggtgtaaa gggaacagtc agtttggcta
     5041 cgatttttat tttgccattt tcaatcaata atatgatgtt ttaccagcgg tctttgcttt
     5101 tgtttctgac ggcgggtgtc atcttagtga ctttggtcat agggatcatt gtcttgccta
     5161 tgctgacgga aacagaggaa gcgaaaagca cggatttgaa tgctttgatg attttagaag
     5221 aggtcgttga agttttgcga aaagaaataa aggaaattga tcgtaataca aaagaatttt
     5281 tagccactga agcagtgata gaaaattatc aagaacggat acgtgatctg tacttggaag
     5341 atttaaccga tgatgaaaag caagaagtac aagaaataca agcactgatt ttgtcgatcg
     5401 aacgggatgg attggatgaa agttatcgtt cgggcaagct ttcttctaat ggttatcgtt
     5461 tttactcccg ttttctttct cgattcgaac attctatcac aagccagatt ttgtctttta
     5521 tcggcttttg gttcattgtt gtccgtaggt taatgcgaat cgttctccat ccgaaaatgt
     5581 tttggcaaag aagatatgct gatcgtcaga catttattag tgatgaagat atccaagaaa
     5641 tcagagagac atatcaaaaa aatactcagt tgattattga aagtttagat aacttgactg
     5701 atatttatga tgaaacgatg gttcaatttt ttatccagca acgcaaactt gaaggaataa
     5761 aaatgaactc ggggaatttg atttcttcgt ggatgatcca gcaagatagt ctgtttacga
     5821 aaaaaatgct aagaggttat tatcttgaaa gaaaaatcat tgatgaatac gaagttgctg
     5881 aaaaaatcac gacgttttct gcgaacagct atcgcaggaa tatcaatttg ttagaatctt
     5941 atacgatgaa caaaccatct gataactttt ctttccgatt tgcgtttcga gcaaagtcaa
     6001 aaaaaacgag tccaataaaa taaaaaggta aaaattttca agttttataa aaaacaaaac
     6061 atatcagaac aggatcgaat cggtcctgtt ctttttttga gaacacaaaa agaacaaata
     6121 ccaaaaaaat tttcctgaag ttcactattt ttatgataca atatccaaga taaggaggga
     6181 acatgttgaa agaattaaaa gtaactgacc tcaaaaaaac ttatggtgaa aaagatttgt
     6241 ttgaccagat ttcttttttg gtccacgaaa aagaccgtat cgggttgatt gggacgaacg
     6301 ggacgggtaa aacaagtctc ttaaatatta ttgccggtat cgatagcagc gacggtgatc
     6361 ggcaaacagt gttttatcca actgattacc gtattggtta tctttctcaa gcagctgaat
     6421 tttccgatga attaactgtt ctccaagcag tctttcaagg aaacagcccc ttgatccaaa
     6481 ctgttcgagc atatgaggaa gcattgatcg aactagggga aaacggagaa gaccctgatg
     6541 tgcaaaaacg ttatgctaaa gcagaagaac aaatgaataa agaagatgct tggactacag
     6601 ataccaacgc aaagattatt ttgcaaaaat taggaatcag tgaattagat aaaaaaatca
     6661 gtactttatc aggtggtcag aaaaaacgag ttagtctggc gcaagtgttg attgatgaac
     6721 ccgatttact attactagac gaaccaacaa accatttaga ttatgaagcg atcgagtggt
     6781 tggaaaacta tttgaaacaa taccgtggcg cactattgat ggttacccac gatcgttatt
     6841 ttctagatag agtagcaaac cgaatcttcg aactttcatt tggaaaatta tacgagtata
     6901 aaggaaatta tgaagcttac gtcttagaaa aagcagaacg tgatcgtgta gaagtagaac
     6961 aagaagaaaa gcgcaagcgg ctttataaac aggaattagc ttggatgagg gctggcgtac
     7021 aggcacgtgg caccaagcag caagcacgga tcaaccgttt cgaagatcta aaggagaact
     7081 tgtaccaagt aaaccaagaa gatgatttag agctgaacct agcgacacaa cgtttaggga
     7141 aaaaagtact ggaaatcaaa gatggcagtt accgtataaa tgaccaaaca ctgctagaac
     7201 atttagattt attgattcaa tctcgggaaa gactaggtat tactggtaaa aatggtgcgg
     7261 gaaaatcgac attgcttaat attctagctg gcagaattcc cctggatagc ggtacaatgt
     7321 ctatcggtga aacggttcat cttgcgtatt atacacaaga aaatgaagaa atggcaccag
     7381 ataaacggat gattgcttac ttacaagaag ctgctgaaga agcaaaaaca gcagatggca
     7441 gtcaaatcgg agtagcagaa ttacttgaac gatttttatt tccaagattt atgcatggga
     7501 cactgatagg caaactttca ggcggagaaa aacgccggtt atttttgttg aaactgctga
     7561 ttcagcaacc taatgtttta ttattggatg aaccgaccaa tgatttggac atagcaacat
     7621 tgacgatttt ggaagattat tttagaagtt ttccaggtgc tgtgatcact gtttcccatg
     7681 accgttattt cttggacaag gtagcagata agttattagt attccaagga aacggaaaac
     7741 aagaacttta ttacggaaac atgtccagtt atttactgaa gcaaaaagag acccagcagc
     7801 ctgctgaaaa agcgaaacca aaaatacaga gcaaggaacc tgctgaaaag aagaaattat
     7861 cttacatgga acaaaaagaa tgggaaacga ttgaagatga gattgcagaa cttgaagaaa
     7921 aaatctcatt gctccaagaa gagatgaatc atcaaggaga taatttcact cgattacaag
     7981 aattgcaaaa cgacgtatct gaaacagaag cacaacttga agaaaaaatg gcacggtggg
     8041 aatacttgag tgaatgggta gaagattagg aggaaaaagg atggaacaag cgtatcttga
     8101 cttaggaaga aaattgttgg aagaagggca tcgtaaagaa gacagaacag gcacaggcac
     8161 attaagctta ttcggatacc aaatgcggtt tgatctgcaa aaagggtttc ctttgttaac
     8221 aacgaaacga gtaccttttg gattgatcaa aagcgaattg ctttggtttt taaaaggaga
     8281 tacgaatatc cgctatctat tacaaaataa aaaccatatt tgggatgaat gggcatttga
     8341 acgctacatc aaaagtccag actataatgg accagatatg actgattttg gccatagatg
     8401 tttgacagat cctgaattca atgaagaata taaaaagcag agcaagcttt tttgcgagaa
     8461 gatcctaacc gatgattcct ttgctgaaac atacggcgat cttggacaca tctacggcta
     8521 tcaatggcgt cactgggaaa caaaagacgg tggctttatc gatcaaatca aacaagtgat
     8581 cgaagcaatc aaaaagactc ctgattctag aagattgatc gtttctgcat ggaatccgga
     8641 agatgttcct agcatggctt tgcctccttg tcatacgatg tttcaatttt atgttcaaga
     8701 gggacggcta agctgccaat tgtatcaacg cagtggggat gtgtttctag gcgttccgtt
     8761 caacattgca agttatgcgt tgctgactca cctaattgca catgaaacag gtttagcggt
     8821 tggcgaattt gttcacacat taggagatgc tcatctttat atcaatcata tcgaacaaat
     8881 gaaagaacaa ttgagccgag aaatacgcgc atttccgact ttagttttga atcaggaaaa
     8941 gcagtcagta tttgattttg agatggaaga tatccaatta gaaggatatg acccacatcc
     9001 ggcgatcaaa gctcctatcg ctgtttagaa tcagaaagga tgagaaaatg ttagctgcaa
     9061 tttgggcaca ggatgaaaac ggattgattg gaaaagaaga ccgtcttcct tggcgtttgc
     9121 caaatgatct gaaattcttc aaacaaatga cagaagcaaa tacactagtg atgggacgaa
     9181 aaacattcga agggatgggt agccgtccgt tgccgaatcg tcagacgatt gttttgacga
     9241 gagattcttc ctataaagca gaaggcgtgc atgtcatgca tagtgtggaa gacgtgcttg
     9301 ctctggaaaa agaaacagac ggtatctttt tcatcgctgg agggtcagct gtttatcaag
     9361 aatttctgcc attttgtacg atattatacc gtacagtcat ccatcatgta ttcgatggag
     9421 atgcttattt tccacctgtt gactggtctg attggtcact gatcaatact agtcaaggag
     9481 aaatggatga aaaaaatcgt tatccgcatc aatttgaaac gtatcagcgt aatgagaatc
     9541 ctgtaaaaag cgggacaggc gaattgacga tataaaaaag ctatggatag actagctgtt
     9601 atttagagct gtcccatcca tagctttatt ttttttatta agtaaagaat aaaacagaga
     9661 agtacataaa acctgcacct aacataacaa acaaatgcca aacaacatgc atatagcgga
     9721 tagaattcaa gctataaaag aatgcgccta tcgtgtaaga aagcccgcct gctaccatca
     9781 aaataacacc agtcattcca agagagtgat aaagaggaac agcagccacg acacagagcc
     9841 accccataaa aatatagatg atcgtagata cttttgatac tctctcccgt ttatgcaacg
     9901 tcaacgcttt atatataatg ccaagaatcg caaacaacca gattaataca aataaagtcc
     9961 aacctagcca tcctcggata ctcagcaaac aaaaaggagt ataacttcct gcaatcaaaa
    10021 gaaaaatcga actatgatcg aatacttgga acaccttttt tgcttttgta aaaatcaatg
    10081 aatgaaacaa agtagacgtt aaaaataaaa gaatcatcat cgatccatag atagcataag
    10141 agacaatatg gagggaggaa tgcaagtggg caccttttac taaaagaacc actagtcccg
    10201 cgatactcaa tccagtccca attccatggg tgactgcatt aaacacttca tttaatattt
    10261 catacgttcg attaaatttc gttttttcca tgaaaacggc tcctttacta ggtgtaatta
    10321 atgaaaaatc attatttgtc tgttatacta aaaatagaaa ttgtcttaca tgtagtttaa
    10381 catgaataag gcatcttgtt aaagaaagag agagagaaaa taatgacaaa tgtaaaaatc
    10441 gtaacagatt cttcatgtac gatggaaaaa aatgtacgcg atgctttagg cattcgtgtc
    10501 atgccgctat ccatcatgat cgacggaaca gtatatcccg atgatgacca actagacggc
    10561 gaaagattta tggaaatgat ggcgaaagca aaaaatctgc ccaaaacaag ccaaccacca
    10621 attggagaat tcatctcgat gtatgatgag ctaggagaag acggcagtga agtgatttcg
    10681 atccatatga caaaaggctt gagtggaaca gtagaagcag caagacaagc cagtaatcta
    10741 acaaaaacga aagtaacggt tatcgacagt gataccactg accaaggatt atcttttcag
    10801 gtaattcgag cagctgaatt agcaaaagaa ggtaaaacag tagagaaaat ccttgaagaa
    10861 gtcaaaaaag tacaagacaa tacaaaatta tacatcggaa tatccacact agataacttg
    10921 gtaaaaggtg gaagaatcag ccgaacaact ggtttgctgt ctagtgtttt gaacatacgc
    10981 gtggtgatga atttcgccca ttctgaatta atccctgtaa ctaaggggcg aggaaagaaa
    11041 acgttcgata aatggtttaa taatttgaaa aatgaactga aagaattgcc aaatgtgcga
    11101 caaatcggta tttcacatgc ggatgcaaaa gaattggcgc aagaattcaa agagggtttg
    11161 caagaattat tcccggacat gcatatccct gtactgcata cgaatccggt tatcgctacg
    11221 catactggta aagacgcgtt tgcaatcatg tattatgtag attagtcgaa aagaggataa
    11281 gccctcagcc tgaaaggctt gcagcttatt ctctttttct ttataaaatt aggaaaataa
    11341 ttgttttctt ttttcataaa gactaccttt ttgataaaat ttttgataac attagaacca
    11401 atcgaataca agaggtgaaa aaatgaaatt aacgaaacga catttgatcc tcgttttgtt
    11461 cccattatta attgcgatca tcatctatgc aggtttagct gcttctatac cgaaagctgg
    11521 cccactaatg aaaccagtaa ctactgtgag agaagatcca aataaaaaag aaaaacttca
    11581 ctacatagct atcggagatt cgctgactga aggagtagga gatcaaacca agcaaggagg
    11641 attcgttccc cttgtcgcaa atgatctaaa agaccgttat aatttgaccg cggttgaaac
    11701 agaaaactat ggtgtaaatg gtgaacgaag tgaccagatc ttaaagcgag taaaaacaaa
    11761 agaagaaatt cgaaacaata tcaaaacagc tgattttatc acactgactg ttggcggtaa
    11821 tgatttgatg aaagttatcc aaaataattt attcgggtta acggtcaatt cctttaaaaa
    11881 gccactgaaa aactatcagg aaaatgtcac agaactattg gaagaatttc gatccctcaa
    11941 taaaaccgca cctatttaca ttttaggcat ctacaatcca ttttatttga actttcctga
    12001 gatcactgac atgcagacaa ttgttaacaa ttggaacaaa ggaacagaaa cggtgacaaa
    12061 aaaaatgccg aactgctact ttatcccaat caatgatttg ctttatcaag gattgaatca
    12121 ggaagtaggt gtcacagaag aaggaacaga tcaaacaact agcacgacag aaaatctaaa
    12181 tggcatcaaa aataatgtgc tctatgaaga agatcatttc catccaaata atttaggtta
    12241 tcaattgatg gcaaatgcag tgagagatca gctgatcgag acacaaaacc aatggttaga
    12301 gaaggaggat gatcaataaa catgaaaaca agatctgacg tatcttcaaa caaaacaaag
    12361 aaaacaaatt actggaaatt cgccttcctt atccttcttg gggtagtact tggttcgacc
    12421 gtatttttag gcagccgtat ttttgctaat cgggaaccag aactcccaga aataccagct
    12481 cttacggaaa gacaaggaga tcctgtctta acgatcaatt caaataaaga aaaagtcaat
    12541 caaatcatca gctttttcct tagtgagtat caaaaagata gtgatattga atataaattt
    12601 tatttggaaa atgaagcact actcaatggt actttcgaag tactaggttt tcctatcgat
    12661 ttctatttat attttgatcc gtatgtgatg gaaaacggaa atgtccaact aaaagctaga
    12721 agtctttcta tcggaacatt gagtttgcca atcaaagatg tgatgaatat gatcaagaga
    12781 aactataaat taccagattg gatcgaagtc aatacagatg atctgactat catgcttagg
    12841 ttggatcaat tccgaatgca aaacgggatg tatattaaag cagataaaat cgacttagta
    12901 aatgatgaca ttcggtttag tctatatttg ccaaaagata cctctgatgc ttcaaacaac
    12961 tcaaatacca acaaaactag caccagcagt actgaaagca agacaaaaga aaataaaaaa
    13021 tcatcggatg agtagtatta gagggggaat cataatggaa cgagcaatat ttgcaggagg
    13081 ctgcttctgg tgtatgatcc agcctttcga cacgcttcct ggtatccata cagtgatgtc
    13141 aggatatact ggagggcatg taccagatcc gacttatgaa caagtaaaaa gccaaacgac
    13201 tggacataca gaagcagtgg agattatcta tgatccaaca ttgatttcat atgaacaatt
    13261 agtagaactt tactggcagc aaactgatcc aactgacgct ttcggacaat tcgaggatcg
    13321 cggtgacaat tatcgcccgg tgatctttta tttgacagaa gaacagcgga tcattgctga
    13381 aaaaagtaag aaacagttag ctgaaagtgg acgtttcgaa cagccaatcg ttacaaaaat
    13441 cgaaccagcc caaccatttt atctagcaga agaagaccat caagagtatt ataaaaagca
    13501 tcctgaaaat tttaaaagaa accatgcacg ccgggctgcc tttatcgaag aaaattggag
    13561 gaacgaaggg tgaatcgaag cttttttcat tatttaatga cactgcgagg cggtggcaca
    13621 catgatgctt tatctgtttt cgctacagaa gccggtaaag acatccaatt tcctaagcac
    13681 agctctagct acgaagaaat ttctaattat ctggaactga atgtcgacta tttgccgtcc
    13741 atggatatct ttgacgaagc atgggaaaaa tatttagaaa ataatcatga catataagag
    13801 atagttttgt actttatgat caaaaaagtt ttttgtccaa tagcctaatt gaaagaatta
    13861 tttttatttc agctatctag tcgcattttt ttgatatttt tcttataata aagaaagaat
    13921 gaaaaaaaga gggatggatt gatagagatt gacaaaaaaa caacgctata ttaatcgctt
    13981 ctggcttgta ttcaaatact tacttgtttc tgtattcctt gcgttcatgt tgcggggatt
    14041 tttattcatc ccggtaccag tggaaggcaa ttcaatggaa aacgtgttga agcaaggtga
    14101 tatggttgtg atggaaaaat tttcggagat cagacgattt gatattgttg tttttcaatt
    14161 agcagatggc acgatttata tcaaacgagt aatcggtctt ccaggagaaa atgtcagcta
    14221 ccaaaatgat caattgaaga tcaatgggaa agtagttaag gaaccttatc taactaaaaa
    14281 cctgaaatca gatcatgcaa atgcatccta tacgacggac tttacactac aagagctaac
    14341 gggacaatcc aagcttccgg aagataatta ttttgtactt ggagataatc gaagagtttc
    14401 aaaagatagt cgttcgtttg gcacgatcaa taaaactgat attctaggta aagcaagatt
    14461 tgtctattat ccacttgatg aaataaaatg gatccagtga gaaacaataa agcgtgcagt
    14521 ctgttgagac tgcacgcttt attgtttaat ccaaaatcag tttactacct tagtacgtaa
    14581 aatcaaacag ctcgtttaaa cacttttcta gcctctaaag ttttgataaa tgaataaaca
    14641 accattattt gaatagggat ttggatcata ttcctgatga atctacctag aaaaattact
    14701 ttgaaatctg caccaaacaa aacagacatc agccaagaat tgataaaaag gctgactggg
    14761 atcataatca ataattgggc agcgatgacg gaaggcaggt ttatcttttt atgatataaa
    14821 aataagccat taataaatcc accaaggaaa gccgtgataa gaaaagcagc ttgaaacgtt
    14881 cctgaaccaa atatcgtgaa atttaaagtg ttcgacaaca tttcaagcaa accagcccag
    14941 atcggtccat atagataacc cataagcgcc atacttaaaa atccgaatgt gatttgaaaa
    15001 taagcaggac caatcgctat cttgtataag atgacatcaa gggctaataa aagagcagag
    15061 gtcgacaaca atcttgcatt catttcgggc aatctaaaaa cgtcttttgc aatcaaagtg
    15121 ttcaaaatat tctctccttt gtcagttaat aataaaagga taccataaaa tcaccaatgt
    15181 gtcatgacac attggtgatt tacatacact ggcatctaac aattaaaaaa agggtgagaa
    15241 gactgctttt ataaactgta aaaaagagat tgtacgaata aaaaaaatag aggcggagaa
    15301 tacttatcgt atcatccgcc tttgtttttt tgttataaaa aacgtcagat tagttatctg
    15361 cttacatctt catccatacg ggttctaatg tatttccgtc tagatcttgg acttctaatg
    15421 aaaacatttc ttcttcaggc attcccatat ctacttcgtg gaaagtacca ccattttctt
    15481 ttgcaatttg agcaaatttt tttacttcat ccgcattttc aacactaaac gaaatcaaag
    15541 caccacttgt ttttttatta tcagctattt ctttatcttt tataaatttt ttataaaaat
    15601 catgagagag aagcattatc caaaaagtgt catcccatac cattgaacca gcttcttcag
    15661 tagaaaattc ttcatttttt ttaaaaccca gcttttcata aaaagcaacg gaacgattga
    15721 catcagcaac aggaaaatta acaaaaacca tactattcat ttgtttcgtc tcctttctgt
    15781 tttgttcgtc tatcatctct tatttaggaa acgctgtcaa aaatttagat tcatatatag
    15841 aaaccaaaat aaaaatttgc atcatcaaaa aagtgaagat gtgatagaat gaggactggt
    15901 tcactttcac ttaactaata gatggaattt cttt
//
LOCUS       DAYNVV010000059        15933 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.062, whole genome shotgun sequence.
ACCESSION   DAYNVV010000059 DAYNVV010000000
VERSION     DAYNVV010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15933
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.062"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            134..3661
                     /locus_tag="ACGXWR_002184"
     CDS             134..3661
                     /locus_tag="ACGXWR_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HFK0803712.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3658..7380
                     /gene="addA"
                     /locus_tag="ACGXWR_002185"
     CDS             3658..7380
                     /gene="addA"
                     /locus_tag="ACGXWR_002185"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HFK0803713.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7449..7790
                     /locus_tag="ACGXWR_002186"
     CDS             7449..7790
                     /locus_tag="ACGXWR_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFK0803714.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8099..9142
                     /gene="pheS"
                     /locus_tag="ACGXWR_002187"
     CDS             8099..9142
                     /gene="pheS"
                     /locus_tag="ACGXWR_002187"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HFK0803715.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9147..11567
                     /gene="pheT"
                     /locus_tag="ACGXWR_002188"
     CDS             9147..11567
                     /gene="pheT"
                     /locus_tag="ACGXWR_002188"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HFK0803716.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11737..12747)
                     /gene="trpS"
                     /locus_tag="ACGXWR_002189"
     CDS             complement(11737..12747)
                     /gene="trpS"
                     /locus_tag="ACGXWR_002189"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HFK0803717.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13001..13738
                     /locus_tag="ACGXWR_002190"
     CDS             13001..13738
                     /locus_tag="ACGXWR_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFK0803718.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13752..14567
                     /locus_tag="ACGXWR_002191"
     CDS             13752..14567
                     /locus_tag="ACGXWR_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFK0803719.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14580..15227
                     /locus_tag="ACGXWR_002192"
     CDS             14580..15227
                     /locus_tag="ACGXWR_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFK0803720.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSTLAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15243..15899
                     /locus_tag="ACGXWR_002193"
     CDS             15243..15899
                     /locus_tag="ACGXWR_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFK0803721.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
BASE COUNT         5342 a         2745 c         3376 g         4470 t
ORIGIN      
        1 ttttttgcgt atacttaaaa aagtagaaat atcagaacct taaaaggata taatttgaag
       61 aatatagaac aaatgttcag tattttttga tataataaag gagcaccgta tcatgtgttg
      121 aaggaggaaa agcatgtctt tacaatttat tcttggaaac gggaaaaaag atcaccgtca
      181 agtcttgatc gacgaagcat ccgcttggct cgaccaggat gcaagtaacc aagtattttt
      241 ccttgttccc aactacagca aattcgaaca ggaacaagaa attttagcgg agatgcgaag
      301 aagaagcgga aaaaaaactt tcagcacaac aaacgttcaa gtatttagtt tttatcgtct
      361 ggcttggtat ttgctgcaac agacaactct tcttacagga aatgaattat cagaatcagg
      421 atctgcaatg atcttgcgac agattttaga aaaaaatgag gaagaattaa caatctttcg
      481 cggagaaatc aataaaagag ggtttattcg tcaattacaa gaactctaca gtgaattgcg
      541 tacaggaaat attcaaccag aagacctgat gcttttattt ggtgattcac ctaatgcaga
      601 agaccagcaa cttaaaatga aagacttgaa gctgattttt tcagcttatg acagcgaatt
      661 gactcaacgt gcactaacaa atgaagatgc actatctata ctagcaaatt atatgcagac
      721 acaagatttc aacaacgtca aatttattgt cagtggtttt tctcgaatca atggtcaaga
      781 gtatcaatta ctgcaggcaa tgatggaaaa ggggcaattg gttgtcgatt tattgctgga
      841 tcgtccttat acagcggatc ttccagaagt acttacgctc tttcatgaga ctggaaagct
      901 ttatttccgt ctttttcaaa gtgcaagaga acggaaagtc cctatattag tggaccgatt
      961 tgcaccagag cagactcgtc cgacagagct tcaactgctg caaacaatgt gggaagagac
     1021 atctagccaa aagaaagcgg cagtacacaa aataggggga caagagcatc tccatttgtg
     1081 ggaagctgaa aatccaactg aagaagtccg acaattagct gttgaaatca gacgactagt
     1141 cagtgaagaa aactaccgtt atcgtgatat ccaagtgctg acaaaaaata tgtctttata
     1201 tggaaatatc cttcggccga tctttcaaga aatggcaatt cctttttata tcgatgaaga
     1261 acaaatgatg gaaaatcatc cgctgatcga atggatcaac agtctgttcg ctcttgaccg
     1321 ctattcttat cggctaagtg atattatgcg ttttttcaaa actgaattat ttctgtcgac
     1381 ggaagcagaa accgaacttg atgaatggaa acaagagcga gatgaattca ggaaaaaact
     1441 ggacatcact gaaaatgtag cacttgctta caattatcaa ggaacttatt ggactcgtga
     1501 aaaagactgg cagtttgtgg cgtatgattt tgaagcagaa cagattgaag acgtacagta
     1561 tttggaagaa cagtcaaata cgattagacg attatttcag aaagctgtac cagtattttt
     1621 gaaaaaaata aagaaaagca aaacaggaca agaggccgca aatgtttttt atcaattttt
     1681 gatccaaagt ggcgtacagc aacaattatt gttttggcgt aatcaggaag tagacagagg
     1741 aaacttagaa gcggcaagaa accatgagca gacatgggga gcgctgattg atctgttgga
     1801 tgaatatgta gtaatttatg gtgaatcggc ttttgactgg tcactgttcc aagaaatcat
     1861 tacaagtggt ctagaaaatc taagttatgg taaaatccct accgcaatcg accaagtgcg
     1921 aatcaatcgt ttggaattag ttcgaccaaa tcaagctgcc gtcacttttg cattagggtt
     1981 gaatgatcaa gtgtttccag accgaaaaga gacaaaagga ttgttgtcca gtgaagaacg
     2041 agaagtatta aatcaggcct tgccagatgg acagttttta ttcgacccat caaaggaaag
     2101 tatctctttt gagcctttcc aagcctatct tgtttttctt tccggaacag atcgattata
     2161 tcttagttat gcacaaagct atgacacaga tggttcgctg aagatgtctc cttatttgcg
     2221 tagaatcaca gaatatttat ctgttcccgt cgagagaaaa gagcatttga cgatcgaaag
     2281 cgaccctaat tgttatgtag ggacttacag aagcggaatc aatacagtca ataggattta
     2341 tcgattagct ttagatgaaa aaaaacctgt accaaagcac tggcaaaagc tcaaagaatt
     2401 agtactgaat tcgtcatggc gaaattttgc tttacagatt tttgaaagtc aggaacattt
     2461 aaatgttcct gtttcgatgc cagaaaaaat ggcggaagag ctttatggaa aagagattta
     2521 tacttcaatt tcacgtatgg agaattttta taattgtgaa tacaaatact tcatgcaatt
     2581 tggtttgaaa ttgaaagaac gaactgttta tggtctaact ccagcagcaa ctggtgattt
     2641 ttatcatgaa tcattggatc gtttcttcaa gctactgttt tcaaaccaat tatccttagt
     2701 gaatatgtcc gatgcgcagc gtagagactt tactgaaaaa gtgctgcagg aagtattcgg
     2761 agaacttcgg tttgagatat tggatagttc tgcaagaatg aactatatcc gctaccagtt
     2821 aggacagacg attcaaaaag tgacatgggc tttgcaaaaa cagagcaaaa atacaggcat
     2881 gcatcctctt cagacagaga ttctatttgg tcagattgct ggagcaaaag gtatcacagg
     2941 tctggaatta ccgttgagta atggtggaaa actccatgtt cgagggaaaa tcgatcgaat
     3001 cgatgtagct tctgaacaag aagatacttg gctaagcgtc gttgattaca aatctagcgg
     3061 acgttcattc gatgtcacag aagcttatta tggcatggct atgcaattat tgacgtatct
     3121 ggacgtagca ttgatggatg cggtacgttt gactggaaag gcggctgtta aaccagcagg
     3181 atcatattat ttacatgttc ataatcctgt attgacggag acagatgatg tagagaagaa
     3241 tacattgaaa aaatttagtt atgatggcgt ttttgtcgat gatcccgctc ttttagaagt
     3301 actagatcat tcactggaag caaaagaaca atcactgatc tatccagtga aaaaaaatgc
     3361 gaaagatgaa taccaaaaag gtagtttcag taaagacaaa tttttcacgg aagaagaact
     3421 gcaactattc atggcgcata atcgggaaaa tatgcggtta gctggagatg cgattacttc
     3481 cggagaaatc aaactaaatc cagcttataa agataaacag cggattgcct gcgaattttg
     3541 tccattcaga agcatctgta cgtttgatgt gatgctgaaa gaaaataatt accaccgtct
     3601 ggagaaaata gataaggaag aagcactgcg tagaatattg aaaaggagtg aagaagagtg
     3661 aatcaaattc ctttaaaacc gcaaaatgaa cgattcacag atgatcagtg gcaagcgatt
     3721 tttgatcaag gagataatct attagtctct gcgtctgccg gatcaggtaa aactacagtg
     3781 cttgttcgaa gagtgattga aaaactaaaa atgggttttg atatcgatga attattgatt
     3841 gtgacattta ctgaagctgc cgcaagagaa atgaaagaaa gaattcaaga ggcattacaa
     3901 gaatccgtca atagcgaaag tgaccctgta cgtagacagc attttactaa gcagttagtt
     3961 ttattgccca cagcgaatat ctcaacctta catgcttttt gcctgacagt tattcgacgt
     4021 tattattact taattgatat tgatccagtc tttcgcatgt taacagatga aacagaaacg
     4081 atcttgatga aggaggatgt gtgggacgag ctgagagaag cactttatgc agaaaatgat
     4141 gaacgatttt tccaattaac aatgaatttt tctaatgatc gttcagatga cggcttgacg
     4201 aatctggtgt tttctcttta tgagtttgcc cgtgccaacc ctgaccccca aaaatggcta
     4261 gaacagttaa gcgataatta tcgtttgcct gaggggctag cgaaatctcg attatatcaa
     4321 aaacaaatcc gtcctttagt tttggcagat atataccaat gtgtacagtt atatgaacag
     4381 atgactcagt tagcacaagg tgaaggatta gaaaaaatgc atgagcaagt agctggagaa
     4441 caacagcaga tcaagaatat ctatgaagcg ttctcgcaag atcggttaga agaagcttat
     4501 gctggtttgg aacaactaac tttttcaact tttaagagca gtcggaaagc agaattgaaa
     4561 gaaatttcca atgaagtcaa gggcatgagg gataaagcaa aaaaactgat tcagcagata
     4621 agtaaaagtt attttcctgt ttccccaagc caaatggaag aattaacgga caaagcacta
     4681 ccgttagtcg aagaaatgac aaaagtcacg caaagcttca tggacggttt cagtatgcgt
     4741 aaacgggaaa aaggtgtgct ggatttcaat gatctggaac atttagcgtt gcagattctc
     4801 acagaaaaaa cgaaagatgt atggctgcca agtgaagctt caaaacatta tcgaaaaaaa
     4861 ttcaaagaag taatggtaga tgaatatcaa gacgtgaacc aattacaaga agccatttta
     4921 tactggctaa gagaacccga tgatacaaaa ggaaatatgt tcatggttgg ggatgtcaaa
     4981 caatccatct attctttccg tttagcagat cctagtttat ttatcgggaa atacgagaat
     5041 ttctcaaaga aagaaggcgg acgtcgaatc gttttggctg agaacttccg ctctagaaaa
     5101 gaagtccttt cttttacgaa tcttattttt gaacaactaa tggatccagc agtgggtcaa
     5161 atcaattatg acgaagcagc caaactgatc caaggatttt cagactttcc agagaatgaa
     5221 cagtttgagc cggaaatcat gatctatgaa aaagaacagg aagaatcaga gattgagatt
     5281 ccgacggatg atatactgga agacaaaaca gaaggcgaac tttttatgac aggactaaaa
     5341 attcgtcaat taattgattc ctcctttatg atttatgata aaaaatcaaa aaaaagtcgt
     5401 ccgatagagt acaaagacat tgttctcttg acacctacaa agaagaacaa cttaacgatt
     5461 ttagagattt tcaaaacatt ggatattcca ttagagatga atgatgctca aaactatttt
     5521 caagcgacag aaattcgcac gatgatctcg ctgctacaat taatcgataa tccctatcaa
     5581 gatattccgc ttgcggctgt attgcgctca ccgatcgtgg gtctgattga accagaatta
     5641 gccagcattc gattagctaa ccgtgcacat acttactatg atgctgtgct tgcttatcaa
     5701 gcatcaaacg aagatgaatt agcagctaag ctggaacatt ttggcaagca actagagcat
     5761 tggcgagaac ttgctcgccg ttcttcgatc actgacttgt tatgggatat ctattatgag
     5821 acgggatatc tagagtatgt ggtcggtctg ccagcagggg cacagagaca agccaatctt
     5881 tatgcattgg ttgatcgtgc caaagcttac gagcaaagtt ctttcagagg attataccag
     5941 ttcgtgcgtt tcattgaaaa aatgcaagaa aaagataaag acttagcaga accagtcatt
     6001 tcaatagaag ataatgctgt tcgcgttatg acgatccatg caagtaaagg cttggaattc
     6061 ccagttgtat ttttgttaga tatgacaaag gagttcaact tacaagactt gcgcaatcgg
     6121 tatgcttttg aagaaaaact tggagcagga attcgctata tggatcctga aacacgagtg
     6181 ttatatgata cgttaccgtt tcaagccatc aaattggcaa agcaaaacaa attgttgtcg
     6241 gaagaaatgc gtaaattgta tgtaggattg actcgggcag aacaaaagct tttcattgtc
     6301 ggttcctata aaaataaaga gcaaatgatc caaacgtggt ctgaagcagc tgatcatgag
     6361 gagttagttt ttgatcctgc gctacgtttg aagggcagaa gcagcttgat gaattggatt
     6421 ggttacggat tgatccgtca tcctgaaatg cagaaatact tagaggaaga aatttcgact
     6481 tctcttcttc aacattcaaa tgcacagttt tctatttcat ggatgaatca gcaatcgatc
     6541 attgaacaaa gacagttgct tgctgaaaaa gaactggtta acttagatca gcagatgaaa
     6601 gaagatgaaa ctttattagc agattcgtta caaaaacgtc tggcatatga atatccttat
     6661 caagcttctt cacaaaccac aagttatcaa tctgtatctg aaatcaaacg attattcgaa
     6721 gatccagatg atacacaaga atcacgtttg actctggaaa gcagtcagaa caaagcagca
     6781 tcccgtcaat ttcgttatac gcaagaacaa ctagcagaac caaaattttt gcaaaaagat
     6841 cggcaagtgt cagcagctgc tgttggaact gctacgcatg ctttgttaca attactgcca
     6901 ttagagatgc caactacaga gagtatccat caaaaattac aggaattggt aaggaaacgg
     6961 ttagtagacg aaaaagtcgc gaaaaaagta gatgtttctt ctattatatg gttctttcaa
     7021 acagaacttg gtcaacagct gattgccaac aaagaaaacg taaaacgaga acaacctttt
     7081 tccatgctgc ttcctgctga cgaagtattt caagactatc caaatcaaga agatgaacta
     7141 ttaatccacg gaatcgtcga tggataccta gaagaaaaag atcatctcaa tatctatgat
     7201 tttaaaacag attttatttt acatccggat gatccagcag aaatagatgc aatcgtccaa
     7261 aaatatcaag gacagctaag actttaccaa caagcaatgt cagaagcttt gaataagcca
     7321 gtagaaaatg ttttcctaat tttgcttcga gtgaaacaaa ttataaacat taacaaataa
     7381 ttataattga gcaaacttga cttatgtttt gtaaggatta tgctatactc tgggaagagg
     7441 tgagtatgat ggagctaaca cagacagaat tcgttttatg ccctaaattt gaaaaaacat
     7501 tctctatttt aggaaaaaaa tggaacggat tgattatcga tgtactactc gaaaacggtc
     7561 cgcaacgctt tgttgagctt gcggcaaaaa tcccgatggt cagtgatcga gtattagtcg
     7621 aacgcttgaa ggaattagaa aaagaaggaa tagtcactcg aaactttgcc tgtagcgaaa
     7681 agagccgttc agaatatctc ttgactgaaa aaggagcaga cttgcaaaaa gcgatgcgtc
     7741 aaatacaagt ttggagcgaa aaatggatca cagaggaaga atgcggttga ttttgtaaaa
     7801 aaaatcttgt aaactatagt ccatacgaat aagtaaagaa cgatgacgaa aaagagtagt
     7861 ttggctaaac cagttcaggg agatctgtcg cagactgaaa gcagatcctg tgtttgaaaa
     7921 atgaagttca ctttccgagt tcgtctgata aaatcagacc ggcaattgtc gttaacgaag
     7981 taagagtgcg gtgtaagtca tttatccgca aattaggatg gtaacgcgaa gacctcgttc
     8041 cttaacagga atgaggtctt tttgttttgt atttggaatt taaaggagga acaagcacat
     8101 gtctctacaa gcacaattag agagcttgaa agaagcaacg ctcgtcaaaa tcacagcggc
     8161 acaagattta aatgaattaa atcaaatacg tgttgaaacg ttaggaaaaa aaggaccgat
     8221 cacagaagta ttacgtggga tgaaagatct aagtccagaa gagcgaccaa aagtcggaag
     8281 tttcgcaaat gagatccgag atcttttgac agaagagatc gagcgaaaaa aacaagtatt
     8341 agaagaagaa gcgttaaatg cagctttggc aaaagaaaca atagacgtga cactacctgg
     8401 tagaaaagta aaacatggta cacgtcatat cgtgacacaa atcatggaag aaattgaaga
     8461 tatttttgtg ggtatgggct atcagatcgt agaaggatat gaagtagaat ctgatcatta
     8521 caatttcgaa cggatgaatc tgccaaaaga tcatccagca agggacatgc aagatacttt
     8581 ctatatttca gacgagatat tgattcggac acatacttca ccagtccaag cacggacaat
     8641 ggaaaaacat gatttctcta agggtgctct acgaatgatc tcgccaggga aagtcttccg
     8701 cagagataca gatgatgcga cccacagtca tcagttccat caaattgaag ggctagttgt
     8761 tgataaaaac atcacaatgg gcgaccttaa aggaacatta gaagtcgtaa tgaaaaaaat
     8821 gtttggggaa gatcgtgaaa ttcgtttgcg tccaagttat ttcccattta cggaaccatc
     8881 agtagaagta gatgtcagct gtttcaaatg tggtggtgcc ggttgtaacg tatgtaaata
     8941 cactggatgg atcgaaattt taggagctgg catggtacac ccgaatgtgt tgaagatgtc
     9001 aggaatcgat ccagaagaat attcaggctt tgctttcggc cttggaccag accgcgtagc
     9061 tatgttgcgg tatggagtga atgatatccg taatttctat caaaatgact tacgtttctt
     9121 aagtcagttc aagggggagt aagaaaatgt tagtttcata taaatggctc aatcgttatg
     9181 tagatttatc gaatgtaaca ccaaaagaat tagcggataa gatgtctgtg acaggaatcg
     9241 aagtagaggg agtaacggtt ccagaagaag gcttgaaaaa aatcgttgtc ggtgaagtca
     9301 aggaatgcgt accacatcca gattctgatc acctttctat ttgtcaagtc gatattggcg
     9361 aagacgaact gtctcaaatc gtttgtggag cgcctaatgt gaaggttgga atcaaagtga
     9421 ttgttgcact tcctaactca cgtatcgctg gtaatgtaaa aatcaaaaaa ggaaaaatgc
     9481 gtggccaagt atcaaatggc atgatttgct cattacaaga aattggctat tcagatagtg
     9541 ttataccgaa agaatacgct gaaggtatct attatatgcc acaagaagct gtaaatggcg
     9601 atccagtttt tccttatttg gatatggatg attcgattat tgaattatct atcacaccga
     9661 atcgtgcgga tgcattgtca atgcgtggcg tagcttatga agttggggca atttatcgtc
     9721 agactcctac attcgatgac gaaaagctgg tagaatcctc acgtcctgct agcgataaaa
     9781 ttcaagtgga agttgaagat aaagaagcag ttcctgctta tcaaatcaga atcattgaag
     9841 gagtaagaat ccagccaagt cctcaatggc tgcaaaatct tttgatgaac gaaggcattc
     9901 gtccaatcaa caatgtagta gatgtgacga actatatttt gcttttattc ggacaaccac
     9961 tacatgcatt tgactacgac aaattgaaat caaaagagat ctttgtccgc cgtgcaaaag
    10021 aaaatgaaac attagtaaca ctagatggag aatctcggga attgacaact gacaatctcg
    10081 tcattactaa cggcaaagaa ccagttgctt tagctggtgt catgggaggg ttagactcag
    10141 agatcacgaa tgaaacaaca acagttgcac tagaatctgc tttatttgat ccaatttcga
    10201 ttcgtcgtac agcaaaacaa tttaatttgc gtagtgaatc ctctgcacgt tttgaaaaag
    10261 gaatcaacca tgcgactgtt ggagaagcca gtgaggttgc tgcagcaatg atcgtttctc
    10321 ttgcgggtgg ggaagttcta caaggcgcgg tcaaaggctc agagatcaaa gcagaagacg
    10381 tatcagtgaa gatttcactt gaacgcatca atcaatattt aggaacatct cttgtcgtta
    10441 aagaagtaaa tgagattttt gaagcacttg gatttagcta tgaagaaaag gagtatgttt
    10501 attccgtagt agtaccacca agacgctggg atatccaaat cgaagcagat attatcgaag
    10561 aagttgctcg tatttatgga tacgaccagt tgccatctac acttccaagt ggagaaacgg
    10621 ttgctggaag cttgtcaaaa gaacaagaaa ctactcgtaa aattcgtaca atctttgaag
    10681 gaagcggatt gagcgaagca atcagttatg cattgacaac agaagaaaaa tcaagacagt
    10741 ttgttataaa tgaaagtaat attacacgtt tggactggcc aatgagcgaa gaacgttctg
    10801 tattacgaat gaatttgatc agcggactat tagatgatat cagttataac actgcccgaa
    10861 aaaatacaga gattgcttta tatgaaattg gtcgggtgtt cttccaagaa aatgatccac
    10921 gtacacatct gccgcaagaa gtaaaacatg cagcaatcgc tatttctggt atttgggaag
    10981 aaaaagattg gcagacgaaa gctcaaaatg tagacttttt caccatcaag ggtcttttag
    11041 aaaacttatt tgaacaacta ggcatcactg aagatgtcca ttatcaaaca gtgacagaaa
    11101 tgaaggaaat gcatcctgga agaactgctg cgatttacct tggcgaaaaa tttattggtt
    11161 ttgtcggtca agtgcatcca acgattacaa aaagttatga tattccagaa acatatgttg
    11221 ctgagtttga tttatctgct atagtggaag ctgctcaaaa agggatcgtt ttcgaagcag
    11281 tgacaaaatt cccagcagtc agccgggaca tcgctttgct tgtaaaagaa actgtgacaa
    11341 atcaggaatt aacagaagtt atccgttctg ctgccggaag atttttaaca gatatccaat
    11401 tatttgatgt ctatcaagga gaaaacattg aaaaaggaca taaatccatg gcgtatagcc
    11461 tgacattcgt caacccagaa gcaacattga cagatgaaga aatcaataaa gcaatggaaa
    11521 aagtcgaaaa agcgttggta gaaaacctag aggcaagtat tcgctaagaa ggaaaatata
    11581 gtaagtaacg atcaagtagc ttttgaagac catacatttg aaaaaaagat gtgacacaac
    11641 ttcgtcacat ctcttttttt gattttaaaa aaggaatagc acagagacga gataaaaaaa
    11701 caggccttta cagcctgctt ttttagagta aatgaattaa tggaagtaat tgattcccat
    11761 tgctgatttt acttcagaaa gtgtttgtgc agctacttta gcagcttctt cactaccttt
    11821 acgtaagatt tccataacag ctgaaggatc tttttccaat tcttctcggc gcgcacggat
    11881 cggtgcaaat tcagcttcca atacatcaat gaggtatcgt ttgatcttta catcaccaag
    11941 tccgccgcgg cggtaatgag ctttcatttc ttcaattgct tctttatctg ttccgaatac
    12001 atccaagtag gtgaagacca tattcccttc tacttgtcca ggatcttgta catggatgtg
    12061 gtttggatca gtatacatac tcatgacttt tttctgtaag acatcggcag gatcggagat
    12121 ataaataccg tttcctaacg atttactcat tttgccattt ccatcgattc caggtaatct
    12181 acccattcct tttggtggga atacgccttt tggttccacc aagacttcac catatgtatg
    12241 attgaagctt tgtacgattt cctgtgtctg ctctagcatt ggtttttgat cctcaccaac
    12301 aggtacaaga ttcgctttga atgcagtgat atctgctgct tgagaaacag gatagataaa
    12361 gaatcctgta ggcacgcttt caccgaattt tttttgttcg atttctgttt tgacagtcgg
    12421 attgcgccga acgcgtccta cgctgactaa gttcaaataa tacatggtta attcagctaa
    12481 ttccggaatt tgtgattgga taaataaagt agattttgca ggatctaatc ccacggctaa
    12541 atagtctaaa gcaacttgca agacatttga tgaaaccttc tcaggatttt tagcattatc
    12601 tgtcagtgct tgcatgtcag caatcatgac aaacagttgg ttgtcttcat ctgcctgcat
    12661 agccactcgg gtttttagag aaccgacgta atgccctaaa tgcagcttcc cagttggtcg
    12721 atctcccgtt aaaataatat ttttcaaaaa agacacctct ttacgatttg taagtctgag
    12781 cacttaatat cttaccgttt ttcctgaaaa gaaacaacag ttcctaagga aaaaacaagg
    12841 aaagaggata aaataactaa tagattagaa atggaagaaa tatttatggg agaataaacg
    12901 ttctaagaaa ctttacaaat tactaaacta tcagatataa tgtattttat tatacatctt
    12961 taaaagaaat cttactaaat aataatggga gtgtaattct atggcaatga ttaaatttga
    13021 tcacgtggat aaatattatg gcaagttcca cgcattaaaa aatatcaatc tcgaattcga
    13081 gaaaggagaa gttgtcgttg tcattggtcc ttctggttca ggaaagagca cgatgcttcg
    13141 ctgtatcaat ggattagaga cgatctcttc aggtaagctg ctgattaatg atactgactt
    13201 gcatgataaa aagacaaaac tgacagaagt ccgaaaaaac atcggcatgg ttttccaaca
    13261 tttcaatttg tacccaaata aaactgttct ggaaaacatc aaattagcac caatcaaagt
    13321 gttgaagcaa gaccaggcaa ctgcagtcaa aaacgcggag aaatttttga aaactgtcaa
    13381 tatgttagat aagaaagatt cttatccttc catgttatcc gggggacaac agcaacgggt
    13441 ggcaatcgcc agaggtttag cgatgaatcc tgagatgctg ctgtttgatg aacctacttc
    13501 tgctttggat ccggaaatga ttggtgatgt attagacgtt atgaaaaaat tggctcatga
    13561 cggtatgtca atgattgtcg tgacacatga aatgggcttt gccaaagaag tggcggatcg
    13621 tgttatcttc atggctgatg gagaagtatt ggaagacagc agaaatgtga gagacttttt
    13681 cgaaaatcca aatgaagtcc gagcacagca atttatcagt aaagttatca atcattgata
    13741 ggaggaaaaa gatgcgcagg ttaaaaaaaa tacgcctgat tttcctttta ggcattgctt
    13801 ttcttgcact agccggatgt aaaggaaatg ggttggcaaa tgaagatatt ttagagcgaa
    13861 gcaaatctac caatgaaatc atctggggtg tcaagtatga tactcgatta tttggaatga
    13921 tggatattga gagcagaact gtacaaggat ttgatgtaga tattgcaaaa gcaatcacta
    13981 aaaagatcct tggtgacaat ggaaaaacag aatttgttga agtcacttct aaaactcgga
    14041 ttccattatt gaaaaacgga aatatcgatg caattattgc aacgatgacg atcacagatg
    14101 aacgaaaaaa acaggttgac ttttcagatg tctatttcga tgctggccaa gctttgttgg
    14161 taaagaaagg aagccaaatc aaaagtgtag atgatttgaa tgcttctaca acggttctag
    14221 cagtcaaagg ttctacatcg gctgcgaata tccgacagca tgcaccagat gcaaaaattt
    14281 tagaattaga aaactatgca gaagcattta ctgctttaca atctggtcag ggagacgcga
    14341 tgactacgga taatgcgatt ttgttaggga ttgcagatga aaatccagag tatgagttag
    14401 ttggtggaac gtttactaat gagccttacg ggattgcgat caacaaaggg caagaaaact
    14461 tcttgaaagc tgttaaccaa gcgctagagg aaatgcatgc agatggcaca tacgataaaa
    14521 tctatcaaaa atggtttcca aatgaaactg aaggaaaagt agagtaaggg ggagaggcaa
    14581 tgagcgaatt gatacaaact tatggaccaa tctttgtcga cgggttcaag atcacattgt
    14641 tttcgagtgt cttagcactt gtgtttagtt tgattatcgg aacgttaatg gcaatcttcc
    14701 aattatcaaa gaataaagta gtgagcacct tagcaaaggc atatgtagaa ttttttagaa
    14761 acattccatt attaatcatc gtgatgtttt tttatgttgt cgtaccgatt tattggttta
    14821 atctagatgg attccaagca ggtacgattg gattaacgat ctatacatct gcttttattg
    14881 ctgaaacagt acgttcaggg attcaaaccg taccaaaagg tcaaacagaa gcaggactat
    14941 cttctggttt tacctattca gaaatcatgc gttatattgt tttaccgcaa gcattcaaaa
    15001 tcgttatccc gccattaggc aaccaattta tcaacctcgt aaaaaactca tctattttag
    15061 caatcgtagc tggtttagat ttgatgtatc aaggagactt gatcgctagt gaaacattca
    15121 ataccttcga tacgtatatc atcgttgggt tattttactt agttatcacg ctaccgttat
    15181 cttacttaat ggtttatctt gagaaaaaat gggcggttcg ttcatagaag gaggggaaat
    15241 acatggattt tagcggcgct ttttcatgga tgaatatccg ttttttattg gaaggattaa
    15301 aggttactgt tgaagtttca ttgttttcga tcatttttag tttcttgatc ggtggtctga
    15361 caggtgtgat tcgttttgcg aatatccctt tcttttccaa aatccttggt gtagtgattg
    15421 atattatacg gaatcttcca ttattattga tcattttctt cacttacttt gccttacctc
    15481 aaatcggcat tcagatgaac atcttctggt ccgctgtcgc agcattaacg atttttgagt
    15541 cagctatgtt gtcggaaatt ttccgagctg gactcaatgc tgttccaaaa ggacagatgg
    15601 aagcaggatt atcaacggga ctgacttatg tagaatcgat gcgaacgatc gtgttaccgc
    15661 aagcatttaa atcaatgatc ccggcaattg tgagccaatt gatttcactg atcaaagata
    15721 cttcattagc agtaatcatt tctttacctg aactttctca tcaggcacgt attatttatg
    15781 gacagaacac caattatgtg cttccgatgt tcatcatcat gacacttatg tacttcgtgg
    15841 tatgttacgc gctttctctg ctttccggtt acttggaaaa gagacggtac agttattaat
    15901 agatgattct tttagcggtt gtggcaaact aaa
//
LOCUS       DAYNVV010000060        15877 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.063, whole genome shotgun sequence.
ACCESSION   DAYNVV010000060 DAYNVV010000000
VERSION     DAYNVV010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15877
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.063"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..350
                     /locus_tag="ACGXWR_002194"
     CDS             <1..350
                     /locus_tag="ACGXWR_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFK0803722.1"
                     /translation="KKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNLFLFDEPTS
                     GLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKKDIKLRVED
                     STLIEQIFNDITK"
     gene            368..937
                     /locus_tag="ACGXWR_002195"
     CDS             368..937
                     /locus_tag="ACGXWR_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HFK0803723.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVVSWVLMQLGSAAGQWIPIWFFTDRFRQDWIDRGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            1047..2801
                     /locus_tag="ACGXWR_002196"
     CDS             1047..2801
                     /locus_tag="ACGXWR_002196"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0803724.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQYLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHRVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            2761..4527
                     /locus_tag="ACGXWR_002197"
     CDS             2761..4527
                     /locus_tag="ACGXWR_002197"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0803725.1"
                     /translation="MQMIGGLTMKNFYKKKFALTDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENAKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            5050..5319
                     /gene="rpsN"
                     /locus_tag="ACGXWR_002198"
     CDS             5050..5319
                     /gene="rpsN"
                     /locus_tag="ACGXWR_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFK0803726.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            5334..5513
                     /gene="rpmF"
                     /locus_tag="ACGXWR_002199"
     CDS             5334..5513
                     /gene="rpmF"
                     /locus_tag="ACGXWR_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFK0803727.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            5545..5922
                     /locus_tag="ACGXWR_002200"
     CDS             5545..5922
                     /locus_tag="ACGXWR_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803728.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            5943..6092
                     /gene="rpmG"
                     /locus_tag="ACGXWR_002201"
     CDS             5943..6092
                     /gene="rpmG"
                     /locus_tag="ACGXWR_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFK0803729.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            6116..7099
                     /locus_tag="ACGXWR_002202"
     CDS             6116..7099
                     /locus_tag="ACGXWR_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFK0803730.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            7129..7251
                     /locus_tag="ACGXWR_002203"
     CDS             7129..7251
                     /locus_tag="ACGXWR_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFK0803731.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            7269..8792
                     /locus_tag="ACGXWR_002204"
     CDS             7269..8792
                     /locus_tag="ACGXWR_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFK0803732.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            8816..9055
                     /locus_tag="ACGXWR_002205"
     CDS             8816..9055
                     /locus_tag="ACGXWR_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0803733.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(9248..9709)
                     /locus_tag="ACGXWR_002206"
     CDS             complement(9248..9709)
                     /locus_tag="ACGXWR_002206"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFK0803734.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(9904..10122)
                     /locus_tag="ACGXWR_002207"
     CDS             complement(9904..10122)
                     /locus_tag="ACGXWR_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0803735.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            10240..11856
                     /locus_tag="ACGXWR_002208"
     CDS             10240..11856
                     /locus_tag="ACGXWR_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFK0803736.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            complement(12097..13437)
                     /locus_tag="ACGXWR_002209"
                     /pseudo
     CDS             complement(12097..13437)
                     /locus_tag="ACGXWR_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(13875..14021)
                     /locus_tag="ACGXWR_002210"
     CDS             complement(13875..14021)
                     /locus_tag="ACGXWR_002210"
                     /inference="COORDINATES: protein motif:HMM:NF012870.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803737.1"
                     /translation="MMDITYIPCNDGRLYLSTYIDLATRILRYYMVDSHMKKEIVVRP
                     LQIY"
     gene            complement(14060..14254)
                     /locus_tag="ACGXWR_002211"
     CDS             complement(14060..14254)
                     /locus_tag="ACGXWR_002211"
                     /inference="COORDINATES: protein motif:HMM:NF024673.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFK0803738.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKC"
     gene            complement(14164..14496)
                     /locus_tag="ACGXWR_002212"
     CDS             complement(14164..14496)
                     /locus_tag="ACGXWR_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFK0803739.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            complement(15010..15201)
                     /locus_tag="ACGXWR_002213"
     CDS             complement(15010..15201)
                     /locus_tag="ACGXWR_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0803740.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            complement(15295..15681)
                     /locus_tag="ACGXWR_002214"
     CDS             complement(15295..15681)
                     /locus_tag="ACGXWR_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFK0803741.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
BASE COUNT         5313 a         2403 c         3039 g         5122 t
ORIGIN      
        1 taaaaaaaat ggaactttat aaaatgaaag atcaattacc gtttgattta tccggtggag
       61 aaaaacaaag attattggtt tctatagctt cattgtcaaa aactaattta tttctatttg
      121 atgaacctac aagtgggttg gattatatca atatggaaag gattgctgac cttattaaag
      181 acttaaaaga aaagggtgca gtagttatag ccactcatga tccggaattt ctttataaaa
      241 catgcaatag aattatttat ttaaaaaatg gtggaataaa aaaagatata aaacttagag
      301 tagaagattc aactttgata gaacagattt ttaatgacat aacgaaatag aattgaggag
      361 aatatatatg aaaacaaaag attatatttt tattggttta gctacagtta tttccctagt
      421 aatttacttt ttttcaataa tggttagtag tattggtggg gcgtttggtc acagcatatc
      481 cccagggatt tttggattat tatctggaat catatttgtt tatattagct ataactaccc
      541 tagaaaagga atttttacta tttacacaat tgttttattg ttatttttta cgttaatggg
      601 cggggcgtac ttaccttggt ttatcagttc gattagtatg gcgatcttag ctgatattat
      661 tctatctgta tttggatatg atcgagcaat tcctcaagtt gtgtcttggg ttctaatgca
      721 actaggcagt gctgccggac agtggattcc catatggttc tttacagatc gttttcgtca
      781 agactggata gatagaggac aatctgctgc aacaatggat gcaatgatcc actacgcggt
      841 gggtatatgg ggaattattt cagtgttagt tgtagcaagt ttatctatga ttggtgtatt
      901 gattggaaga aaagtcttaa aaaaatacaa aaaatagaac gtagtttacc ttctatctgt
      961 ttgtacatct ctaatttacg ctattacgga aagcattaac agttgtaaac gaataagaga
     1021 agaaattgaa tgcgggggag gaaaaaatga aagtatacaa aaaattattt agttatgtcc
     1081 ctaaaatgaa atactacgga tggttagcca ctttattttc tgatttttct gtcgtattaa
     1141 cagtctatgg atattacagt atttacaaat ttcttcagtc tctaattatt gtaggagatg
     1201 aatatttagc taagagttat gcggttcaaa ctgttgcttg gttaacttta ggagctttat
     1261 tttatatttt ttctggctta ttttctcata tccttgggtt tcgcttagag actaatttga
     1321 gaaaaaaggg aattagcggt ttaacagaag caagttttcg tttttttgat ttaaattctt
     1381 cgggatatat tcgaaagaca attgatgaca acgcggctaa aacacatatg gcaattgctc
     1441 acttgattcc agatagtgct caagccatag taacacctgt tttatcagtt gccttaggct
     1501 ttttcattaa ctttaaaatt ggattggttc taatcgccat gttagtaatt ggtgtattct
     1561 tgttaaagaa aatgacagag aatacaaatt ttattcaaaa atatcaagaa tcgttagatg
     1621 tgttaagctc tgaaacggta gaatatatcc gcggaattca agttataaag atatttggtg
     1681 ctaaagtaac atcatttaaa gccttgaata aagcaattaa cgattatgct aagtttgcat
     1741 ataagtattc tttgagtggg aaaacacctt ttgttctttt tcaatggcta ttttttggca
     1801 tagtttgcat tttgatagtt cctataacct tttttataac ttctcttacc actcccaaga
     1861 tcttagctgt tgacttgttg atgttgtttt ttttaagtgg aattattttt gtttctttca
     1921 tgagaataat gtatgtaagt atgcacttgt ttgaagcaag atatgcagtc gaaacactag
     1981 actcccttta tttagaaatg aagcaagacc aactaaaata tgggaacgag acacagatta
     2041 aaaattgtga cattgcattt gaaaatgtca gcttttcata caaagaagag tgtgttttag
     2101 aaaatttcaa cttagtttta gaacaaaaaa gaatttatgc attagtagga aaatcaggaa
     2161 gcggaaagag tacgatagct aaactaattt caggtttcta caatgtggat aagggacaga
     2221 ttaaaattgg tggtaagcct ttaaatcact attcaaaaga cacaattatt aacacaattg
     2281 cttttgtctt tcaagatacg aaactattca atcagagtat ttacgataac gtttctatag
     2341 caaatcctca agcgccagca agtaaagtat ttgacgcgct aagattagcc ggttgcgaat
     2401 cgattttaga aaaatttccc gaaagagagc ataccttaat tggtagtaaa ggagtttatc
     2461 tgtcaggagg agaaaaacaa cgtatagcta ttgccagagc aattttaaaa gatgcaaaga
     2521 ttgttattat ggatgaagcc agtgcatcta ttgatccaga taatgagtat gaactacaaa
     2581 aggcttttca atatttgatg aaagaaaaaa cagttattat gatagctcat cgattatcca
     2641 gcattaaatc tgtagatgaa attcttgtct tgtcagaagg aaaaatagta gaacgtggaa
     2701 atcataatga attaatggct aaacatcgag tgtataaaca attggtcact aattatgaga
     2761 atgcaaatga ttggaggctt gacaatgaaa aatttttata aaaaaaaatt tgctttaact
     2821 gatcagggcg cagaagcttt aactaaagct tctatttcta gtttttttgt atactgcatt
     2881 aatatggtac cagcattcat tataatgatg ctgatagacg aattagtttt agaaaatgca
     2941 aagccccgtt ggctttattt tgcagtatcg tttgttactt tgcttttcat gtattggttg
     3001 ttagataggg agtatgaaaa cttatataat agtacttata aagaaagtgc gcatttaaga
     3061 gtgcaaattg cagacgattt gtcaaattta ccattatcct atttttcaaa acataattta
     3121 tcagatttat ctcaaactat catgtctgac gttgaaggta ttgagcatgc gatgagtcat
     3181 gcaataccta aagccggcgg tatggctctg tttttccctt ttatttcagt gatgcttttg
     3241 gttggtaatg tcaaaatggg attagctgtt attttgccaa cgttatttag ttttgtctta
     3301 atcttgttat caaagaaatc ccaaacgaaa gccaatacta aatattacga tactttgaga
     3361 gaaaactcgg aagaatttca agaaactatt gaattgcagc aagagattaa tagctttaat
     3421 ctatctaaaa aagttcaaga cagacttttc aaaaaaatgg aagagagtga aaggattcat
     3481 ttaaaggtag aattaagtac tttttcagtc atggccttat cctctatttt ctcatatgtt
     3541 agtttagcag tagtcattct agtaggtgtt cacttactgt taacgggtga agtgactata
     3601 ctctacgtcg ttggttactt actagccgca ataaaaataa aggattcctt cgattctatg
     3661 aaagaagcag tgcttgaaat attttattta gctcctaaaa tacagcgaat tagagctatg
     3721 aaggaaacca gtatccaaga gggatcagat agtcctctga aatcttttga cattgagttg
     3781 cgagatgtct ctttctcata tgataacaat accccaattt tagatcatat ctcttttacg
     3841 gctaaacaag gagaagtgac tgcgttagta ggtgctagtg gttccgggaa aactagtatc
     3901 ttgaaattag tgtctagact gtatgattat gatgaaggct gtattttaat tgatgggtat
     3961 gatattaaac gtgtatctcc agcttctttg tttagcaaaa tcgctattgt ttttcaagag
     4021 gtaactttgt ttaatacaag tattttggaa aatatacgta ttggaaatag tcaagcgtca
     4081 gatgaggaag tgaaaaaagc agctcgttta gctaactgcg aagactttat tgaaaaacta
     4141 cctgacggtt atcatacatt ggtcggagaa aacggaagtt cactttctgg aggagagcga
     4201 caacgcctat ccatagcacg ggcttttttg aaaaatgcgc caattttaat tttagatgaa
     4261 attactgcca gtttagatgc ggaaaatgaa aaacgtattc aggaaagttt aaatcgttta
     4321 atacaagata agacagtact aattatatcg catcgcttga agtctattga aaaggtaaat
     4381 aaaattgtag tgatggatca aggaaaacta gttgatcaag gtactcataa tgagttgtat
     4441 cgaaggtcag aaatatacaa aaatctcata aagaaaacta aactatctga gaaattcgtc
     4501 tatgaaaaag aagctcaatc acgatgatga aataggcttt aaattaacct acaatttttg
     4561 ggatatagtt ataattcttt ttcaaaaaga ataattttat taaacagcat ctaattttga
     4621 atacacgaaa gaatcagtat gattgaatta gttcacttaa tgtctattct tataatataa
     4681 ggaataatca aagttttaaa aaattggcga taaaccagtt aaacataaaa gattgaataa
     4741 aaagttatag tttctttcat attgccgttt taagtagagg aaaagctact taaaacggta
     4801 tttgtgtttg attggactaa taaaagtgaa ttcttatttt tcagagccta aactgcatat
     4861 tcttttaaat gatttgatta tctctatgta ccgataaatt cgttttcaaa tagttatcta
     4921 ttcatatgag ttttatttca tgttatttat tgttgacaag agcaactctt gttggtaaag
     4981 tatcagtgtc aaaacgtaac gattacgatt tgaggtgtct aaatcaaaat aaaaggagta
     5041 taaaggtata tggcaaaaaa gtcgaaaatt gctaaagcaa agaaacaaat ggcgatgatt
     5101 gaaaagtatg cagataaacg tcaggaatta aaagccgcag gagatcgcac cgctctcgct
     5161 aaattgccaa gagattcaaa tccgaatcgt ctgaggcttc gtgatcagac ggatggtcgt
     5221 ccaagagggt atatgcgaaa gttcggtatg tcccgtatta agtttagaga acttgcccat
     5281 caagggttga ttcctggagt aaaaaaagca agttggtaaa aggaggaaat atcatggcag
     5341 taccagcaag aaaaacatct aaggcgaaga aacggttaag aagaactcat caaactgtag
     5401 taaaaccaga aatttcattt gacgaagcga atggtgatta tagacgtagc catcatgtat
     5461 ctttaaaagg gtactataat ggaaagaaag taattaaagg agcttcaaaa tagtttaata
     5521 tataactttt aggagggaat caaaatggaa attatttacc cacctttagt tgaagaagga
     5581 ttaaagtatt atcttgaaac gacccagcaa tcgctagata aatgcacttt ttatcgttcg
     5641 atggtagaga gaggaattat tactgaaacg ggtttaccga cccaacaggc aattgaaaat
     5701 ggattagtca aagattacta tgaggaccaa ggcttatcat ttgatgattt tttaagaatc
     5761 tatccaattt ttgaagagta tgacgaggag ttatttcaat gtatcgatgg ttattgggag
     5821 atacctgttg atatgaaaga aaatttagtt tcacaattgg aatctggcga gttaactttt
     5881 gaagatgcac aacaaattca agcatatctt gaagatcgat aagtattgaa ggaggaagat
     5941 ttatgcgtca aaatattatt ttggaatgtg tcgaaactgg agaacgtctg tatctcacca
     6001 gcaaaaataa acggaataac cctgaacggt tagaattaaa aaagtattcg ccaaaattgc
     6061 gcagacgggc aatttttaaa gaagtgaaat agctaagtgg taaaaaggtg acaaaatggg
     6121 cataccagtt acaatcgttt ctgggttttt aggggctgga aaaacaacgc taatcaatca
     6181 agccttgcaa gtctcaccct accccaggga agaaattatt ataattgaaa atgagtttgg
     6241 tgaagttggg attgatcaca aattattagt tcatagcgag gaacgggtgt tacaactaaa
     6301 taatggatgt atgtgttgca gtcttcgcag tgatttatta gcaatattga tttctttact
     6361 ggaaacaata gaagaacatc aacaaccaat ttcacaaatc atcattgaaa ctacaggtat
     6421 agcagatccc caaccaatca ttcaaacact tttaacagcg cctcaactaa gaggaagagt
     6481 atatatcgat agtttattga ctgttattga tagtgacagt tttgaactta ttgaaagaga
     6541 accacaagcc cttaagcaac ttgtcatggc agatcgcatt tttgtgtcta gaaaacaaaa
     6601 cttgaattta tctgcactaa aaaaattaca gagagaaatc aaaagtatta accctttatc
     6661 cgatattcga atgttcacac atagtgaaac gattcaaaaa aaggattttt ataatttgaa
     6721 aaaatttaat catcccttag tttttgaaag tgattcatca gaaaatcact ataatggcaa
     6781 atactatcat caacaccatc aagtacatga gtttaaatca attctcttaa cttcagatca
     6841 agacataaaa aaagattttt tactccaatg gattgactgg ctgattttaa ccaaccaagg
     6901 gagcctgtat cgttttaaag gattgattgc tttacaagag caggatttta tagttgccat
     6961 gcaagaggta aacgaacagg ttaattttca atacaccact cgacaaaaag accaaaccac
     7021 tattattcta atcggaaaaa tgttggatga agaaaggatc aaacagagtt ttgataaatt
     7081 actggcggaa agcaaataat gataagtagt gattgggggt aatttctaat ggagaaaacg
     7141 gatatatcta gtgcatatcg acgacttaaa agcccgaata ttaaaactag aaaaagggca
     7201 ttaaaaatta tcaaagaaca taaacgaaat aaaatgaaga aattagcata attaaggaag
     7261 gaaaaagaat gaagaaaatc agtgtaggac ttattgggat agcagctcta ggattattgg
     7321 gagcttgctc cagcactaat gatgcaaaag tatcgaatga taaagatgga aaattagaaa
     7381 ttgtaacaac attctatcca atgtatgatt tcaccaaaaa catcgtcggc gatgaagcga
     7441 acgtggattt aatggttcca gcgggatcag aacctcatga ctatgagccc tcagctaagg
     7501 atatggcaaa agctcatgat gctgatgttt ttgtatatca taacgaaaac atggaatcat
     7561 gggtaccaaa agctaaagaa agttggaaga aagctgggcc taatgtagta gaaggaacaa
     7621 aagacatgat tttattgcca ggtagtgaag aagaagatca tgatcacgga gaagaagatc
     7681 accatcatga actagatcct catacgtggg tttcacccaa aatggcaatt aaggaagttt
     7741 caaatatcaa ggatcagtta gttaaattgt atccgaaaaa agcaaaagta tttgagacaa
     7801 atgctgaaaa gtatttgact aaactgaaac ggttggatgc tgactatacc actagtctta
     7861 aagaagcgaa acaaaaaagt tttgtgacgc aacacgcagc ctttggatat ttagctttgg
     7921 attatggatt gaaacaagtt cctattgctg gactaagtcc tgaagaagag ccatcttctg
     7981 gtcgattagc tgaattaaaa gagtatgtta aaaaaaataa gatcaattat atttactttg
     8041 aaaagaatgc taatgataaa attgcaaaaa ctttggccaa cgaagctggg ataaaattgg
     8101 aagtactgaa tcctcttgaa agtcttacaa aagaacaaat ggataatggt gaagattatg
     8161 tttcagtaat ggaagacaat ctaaaagcgt tagaaaaaac aactatggtt gctggtgaag
     8221 aggtagttcc agaaaaagaa gcgaaggatg aaaagacagt tgctaatggg tactttaaag
     8281 atgccgatgt gaaggatcgc gaattgagtg attatacagg cgaatggcaa tctgtttatc
     8341 cgttgttaaa agatggaatt ttggatgaag ttttcgatta caaagcaaaa atcaataaag
     8401 acatgacagc tgccgagtac aaagattatt atactactgg ctataagaca gatattgata
     8461 ctatcaacat taaagacaac accattgatt ttgtagtcaa cggtgaacat catcaataca
     8521 catacaaata tgttggatac aaaattttga attatgaaaa aggaaaccgt ggtgttcgtt
     8581 ttaattttga aactgatgat gcaggtgctg gtcgttttaa atatattcaa tttagtgatc
     8641 atggaattgc accaagtaag gcagagcatt tccatatttt ctttggtgga gaaagtcaag
     8701 aaaaactcta taatgaattg cataattggc ctactttcta tccagcttca ttgtctaaac
     8761 atgaaattgc tcaagaaatg atggctcatt aaaattcaat ttttggagga aatacatggt
     8821 aagaaaagta ttattgtcta tggattccaa gaatattgat gcttatcggc gttatcgatt
     8881 tgcaaagcaa atgagattaa atgggagtac attagctgat attgctgcaa ctttacatgt
     8941 tagtattgac acagttcata gagtattaaa acgggatcct gattgttgtt ttatcaaggt
     9001 caatactgga agaagtagac gtttagcaaa acggcataat agcttggcca attaattgat
     9061 aataccagag tagatcattt ttcccttatt tggatttgat ctgcttttta ttatgtcttg
     9121 aattgtcaaa tcaagcgcaa cactttatca aagaagactt cataaggtgt tctccaatct
     9181 aaacactttc taggtctgtt attcagtttt tcaatcatct gatttatcgt tgagttatct
     9241 accgtagcta tctctttcga ttttggcaag tattctcgaa tgagtctatt cgtattttaa
     9301 tttgttcatt gttgccaagg gcatgaggat ctggaaaata aaagggcata ttattcaatg
     9361 cttctgtaac tgcgaaatga ttggagaatt cttttcctct atctggagtg atcgttttga
     9421 ccgcctcatt tggaatactg cttaaaagtt caatcatttt ctcgctcaca taagcggctt
     9481 tctttctggg gaccttcttt cctgctaaaa ggaagcatga ttttctgtct gtcaaagtca
     9541 ctaaacaagt accaccagtt ttgccagcta caatatcggc tttccaatga ccaaaatcac
     9601 ttctatcatc tgcggatttt ggacggccat ggatcgaatg agtaaggcaa atctttccac
     9661 gagactcgac atgatttttt gtatgtcttg tttttcctcg atggtgcaat gaacggatca
     9721 ggcctttatt gccgtgtgag aggggttctg tatcgaaaag atcattgcaa attgcacgtt
     9781 agatcgtgat aaaactaatt gaaaagtcca tatgttcatg cttcaaacga ttcgagattt
     9841 cctctggcga ccactgaaaa tcgacaaata aatgacgaac aattgaccaa actcacggat
     9901 catttagaat gtgataacgt ccgcattttt ttcttcgata agcataattt ttttccgctt
     9961 tggaaggtga atagtttttt tcttgtttct tctcagttca tgtaaaatag taaacgggct
    10021 atgctgaatg tcgttgccaa ttatactaat agaaaatcct tcttcgtgaa gcagaaagat
    10081 tctttctcgt tcgagtatag taagatgacg atactggctc ataattattt tccttctagg
    10141 agtgttctcg acaaacttat actagttgga tatcgattat gactcatttt tatgtgttgc
    10201 acttaaagtg taaattcaag gtatagaaag aggttcccta tgaaaaaaat acctattaca
    10261 atcttaactg gctatcttgg ttcaggaaaa acgatacttc taaatcatat tctgtacggt
    10321 gatcacggaa aggaaattgc tgtcattgta aatgacatag gggaagtaaa tgttgatggg
    10381 gtattagtcg acaagaaagg ttttaaaaga actggagaaa aacttgtttc gatgccgaat
    10441 ggatgcattt gttgtacatt acgcgaagat ttgattgttg aactagatca attagtgcaa
    10501 ttttctgact tgaatcaaat tgttattgaa gcttcaggaa tcagcaaacc aattccaatt
    10561 attcaagcaa ttatattagc taaaaaccct ttagacattg atttgaccca acgattagag
    10621 attggtgcca ttattatagt agtggatgta aaacgttttt gggataattt cgaaacgggt
    10681 gaaaagattc aggaaagaaa agctgaaggt aatgtagttg aagaagaaca ggatattcgt
    10741 ggcttgttaa ttgatcaatt cgagtgttgt aacatattac ttttaaataa tagtgactta
    10801 gtgtcaacca agacgattta caaaattaac ggtctaattg ctaagttaca gtccaatgcc
    10861 aaaataatta ggacaattaa aggtgaagta gacttatcga aaattctaaa tacaaatctt
    10921 tttaatatag atgagacttc ctattcagtg ggctggttca aagagttaga gcttggctat
    10981 caaaatcata ttcctgaaac agaagaatat ggtatctcaa gttttatcta tcgaaatcgg
    11041 ttactccttg acgcacaaaa atttgcccat cttacggata aaaattttcc tggcaatatt
    11101 acaagagcaa aagggtttct ttggtttgcc caacatagtg atttttcgac gatctttgaa
    11161 acatcgggta gctataaaag tattgaatca ttaaattatt gggtagctag tttacctaaa
    11221 attgagtgtc aaatgattat acaaaaaaat cccgaattga aggaagcctg gcatccgttg
    11281 tttggtgaac gcattaataa actagttttt attggtatga agatggatca acaatgtatt
    11341 aaggaacaac ttgagggttg tttaactgat tctcttaatg cagataattt ccgaaaaatt
    11401 tcaccatttc catggaaaaa gtctaatatg tttagccaga tatcgttaat gaaattttta
    11461 agaaaagctg gtgtcaagat aggcgatgtc ataattattg gcattttgat tattacctct
    11521 tttattccct tatttgtatt ctctatagaa aaggagaatg aaacaactga agatgctatc
    11581 aaatatgcca tcgttcgaat tgatggcaag gaaatggatc gcttcgattt ggataagatc
    11641 aatcataaac tcgtgaatta tcatcctgcg aagggacaat ataatattgt tgagattaaa
    11701 gatggaagaa ttcgagttaa agaagataat agtcctgatc aaatcgcggt tagaactgga
    11761 tggatctcaa aacccggtca aacgagtatt tgtttacccc ataagttagt tattagtatt
    11821 gagaaaaaag aaagcacaga ttactacatt tactaatctg gaaatagatg aggaggtttt
    11881 taataagaaa aagatattat tattaataat agcaggggct ttattaagtg tgttaagcgc
    11941 ttgtggacaa gaaaaagaag cggtgacaac aggcacaagt atctttaacg ggacctgcaa
    12001 tggtttagtt aacagtcggt tagattactt attttggctc ttcgtcaatg agtgttggtg
    12061 aagaaattca atagaataat cgagatactc acacggctag acagctatct tgtctagccg
    12121 tgttgttgtt ctggctttag tcagttgggt agtattctta gttttcttaa aatattttcc
    12181 tcgatataaa aagattcgtt ctcggtagtt ttgaaagttt ctatagccat aggcaattcg
    12241 ttttagtact ttgatatggt tattcaaaca ttctataggg ccgttggaat agggaacgcg
    12301 caacgctcgt ttgatttctg tttggtattt cttgaaggtc gtgaacactg gttggtagtg
    12361 ctctggcaac tccttgtagt cttcttttag gagcgcgacg aattcaggaa catcttgtct
    12421 tctgataacg gaaagaaaat cctggtagac ttcgtagcct cgctttaagg aatcatcata
    12481 agataatagc cgatcgacta tctctgcttc tgtcagatga tctcgaaatg acggacgcca
    12541 gtagcgatgc tgacctttca attcccacgc attcttttga agtagtttcc agtatttctt
    12601 taagtgcttc gaccgacgat cccctttttt aaaggtcttc attacttgaa ttcggtggtt
    12661 ggtaaaagcc cgaccaatgt gttggctaat atgaaagcga tcggcgacga ttcgggcatt
    12721 cggaaaacac tctttcacca atgtgcgata gggtgtatag aaatctgaaa ccactagacg
    12781 cacttgttca cggactttta tagggtagcg caagaaatag tcgcgtaaag gattgagttg
    12841 ccgattttcc acaatatcaa tcagttgatg ggtcttgccg tccatcatga caaagctcat
    12901 ggctcccgag acatttttca ctgatttgaa ttcatcgaaa cacaccactt ctggtaacag
    12961 ctggctcaaa gaaatggttt taggccgaag gctgcgaagt attcgaatga cagtggtcgg
    13021 agaaatgtgc ttcatacgtg cgatcaaaga catagaaaga ggttcgctta atagctcaag
    13081 aatggcttgt ttgactctgc gagcaatgga gcagcgacga tcactaactg aatcttctgc
    13141 taaaaaagtc tttccacagt gtttacattt gaagcgctgt ttgttaatcc gcagaatggt
    13201 cttgtagtta ctgacatcat tcaataagat ggatactttt ttccagccct atttaatgat
    13261 cgtttgttca ttttgatagt ggcgatgaaa gcattcctcc ggttgatagg tcaatgtgcc
    13321 atcaaaaaca aaacatgttt cgtcattgat tcgctctttg cgaaaggcat cttcatgaaa
    13381 gataagattt aggtctagaa tatctagtaa ctctttggta aactctgaat aggacatctt
    13441 gaaacactcc tttgaatggt tttcgtcgac tttattctaa aggattttaa ggtgtctgtt
    13501 tgcgtttatt agaaaaaaga aaaagtattg gcaacagaag gcgtcaccaa cactagatat
    13561 tatagatccc ttattttctt cgcttcaaat tgtcaaggag tcatcataaa ttttgtatgg
    13621 attcttttgt ttgggtagta gtcttctaaa taatcttgga ttaacacctt catctctatt
    13681 ttacttttat atttgttgga gtcgattaat tctcatttga ttgatcgatg aaacgcttca
    13741 attactgcat tgtcaacagg agtcccagtt tggctcactg aatgtgtgat gtggtggtcg
    13801 ttcaacagct cttgataaat aaaagaccga tgctggctac ctctatcgga atgaattacc
    13861 gtaggcaatt ctccttaata aatttgtaat ggacggacga caatctcttt tttcatgtgt
    13921 gaatctacca tatagtaacg tagaatacga gttgctaagt caatataggt ggacaaatag
    13981 aggcgaccgt cattacatgg aatgtaagta atatccatca cccaaacagc atcaatttgg
    14041 ttctgttcaa attatcgatt caacattttt ttaccatttc tttgattgtt ttttctctac
    14101 catgagaaga tttgcgtcga tgaaatcctc ttgtgcataa attcatttca cgcataagaa
    14161 cagctacaac acgtttattg atttcgattc cttcatcgta aagtttttga gtgatccctg
    14221 gagatccgta tcgatctttg tgttcgtaga acactcgtct tcctctttta gtcgtttatt
    14281 ttcctgttca agaatgtaga aatctgcttt atcaggtaat ctttttcctt gtccagcaaa
    14341 agcatttttc ccgtatcgac gatattctga aacccatcgg gaaattgttg gacgagagat
    14401 attgtattct tcagcaattt tcttggtagt tacttttttc tcaaggatat cctgtgaaat
    14461 ctttagttta aatttacgat catatgtttt tctcaataga gttcattcct tccggtaacg
    14521 taactgatag tcaagaaaag tgtatcatag cccaacttag tatcagggtt tgtcaactaa
    14581 actgtggaag ttgatagata agagttttta acaaccaaaa ttctcttgac tatttttgaa
    14641 atcagacaaa ttttgattgg acacatagtt gaataaatct accgtcgtta cggaaggtaa
    14701 atcgcatgct tttcaattct agaggagaag tcctcgttga agtaccatag cccagttctg
    14761 gattcgacct cctgcccact tcatacgtaa ataaagtaat tttaggagtg agactgtgac
    14821 aaaagttatt tttaagctaa aaacgaatta aaaaacgttg ataattaaaa tcattcgttt
    14881 tagattctat gaatcattat agaacgctgt aaaatcgata ctttataatt ataaagaaga
    14941 tagtttcaaa tttattgttc gaaatttgaa actatctttt tacttatgtc acagactccc
    15001 ttagttgagt tattctttaa tttcgaattt cgagatagct agatatattg caagcataca
    15061 ttcttgataa caatcttgat catattttcc agttctccag gattgcttat gaatcaaaga
    15121 gctaaatctt ttgagaattg cctcaacagc ttcttcattt ccagcctttg ctaaaatgaa
    15181 atcttctttt aaagaattca taaatctacc ttcttcccat ggacttataa tctatttctt
    15241 tgggaaggag gagaacgagc aaagaagcat acaaaattag ttattatgca gatattaaac
    15301 cagcattttt tgaatttttt tgtaaagtcg atgttttaaa tttgtcgcac cctgtcttgt
    15361 aatccccaga acctttccaa tttctttatc agttttatca aagataaatt tttcgataag
    15421 aaaaatttgt tcaggttctt tcaacaaagg aaggattttt gctaatttta tatcttcaac
    15481 aaggagagtc acatttaaaa cattaatcgg ttgtttaaat tttatagtat ctttagtaaa
    15541 caaatatggt gggagttgat caagttgttc atgtttttga atttcttctt gttttttata
    15601 ataagtatta gcggtgttca aaatgacctt ttcaaagaat cgaatcaact gggcatttac
    15661 gcgttcgtcg ttatctgaca tattgcacac ctcctccatt aagatttaaa gggaaaagag
    15721 gcaaaaaaca cgaaaagaag ctaatgcaat tatgctgcgc tgcgaataac ttctataagc
    15781 tcacatgcat tgataggact gctgatgttt attttcaaaa atgttttttt agttgataat
    15841 ggatagttat ctttatactt agaaaagaaa attcata
//
LOCUS       DAYNVV010000061        15707 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.064, whole genome shotgun sequence.
ACCESSION   DAYNVV010000061 DAYNVV010000000
VERSION     DAYNVV010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15707
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.064"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..1065)
                     /locus_tag="ACGXWR_002215"
     CDS             complement(<1..1065)
                     /locus_tag="ACGXWR_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0803742.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQNPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKI"
     gene            complement(1076..1744)
                     /locus_tag="ACGXWR_002216"
     CDS             complement(1076..1744)
                     /locus_tag="ACGXWR_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HFK0803743.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(1875..2459)
                     /locus_tag="ACGXWR_002217"
     CDS             complement(1875..2459)
                     /locus_tag="ACGXWR_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFK0803744.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(2790..3023)
                     /locus_tag="ACGXWR_002218"
     CDS             complement(2790..3023)
                     /locus_tag="ACGXWR_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFK0803745.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(3038..3988)
                     /locus_tag="ACGXWR_002219"
     CDS             complement(3038..3988)
                     /locus_tag="ACGXWR_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein"
                     /protein_id="HFK0803746.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(3985..4827)
                     /locus_tag="ACGXWR_002220"
     CDS             complement(3985..4827)
                     /locus_tag="ACGXWR_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HFK0803747.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            5149..6336
                     /locus_tag="ACGXWR_002221"
     CDS             5149..6336
                     /locus_tag="ACGXWR_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFK0803748.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
     gene            complement(6428..7168)
                     /locus_tag="ACGXWR_002222"
     CDS             complement(6428..7168)
                     /locus_tag="ACGXWR_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFK0803749.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGETNYIESSKN"
     gene            8086..9312
                     /locus_tag="ACGXWR_002223"
     CDS             8086..9312
                     /locus_tag="ACGXWR_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFK0803750.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGITSEKYQKVFPTRQLAIKA
                     ENAMKRKIETVLREENANSLELKGKIKFKEFYESKWLPRYELGQTTRSKRAPSYVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQCITAPKKIALEERRIREGNQALSSEELIAWIEAVNTDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFEKQTVRLKHALDKYQKKKFTKGRKDTV
                     IQVPEIVMALLSKWKSVQAEQLLRLKINQTPDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPELAHLSPHKLRHTYATIARQGGANMNQISSALTHSDISTTRIYVNTPDVV
                     DKTVFEAFQRGLNKCD"
     gene            complement(9472..10089)
                     /locus_tag="ACGXWR_002224"
     CDS             complement(9472..10089)
                     /locus_tag="ACGXWR_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFK0803751.1"
                     /translation="MAKIGYARVSSLDQNLDRQLELLSECDKIFSDKASGKDTNREGF
                     QEMMKFIREGDIVVVTELKRLGRNNKELTETMNLIQLKKATLEVLNLPALTGITDDNL
                     RRLLNNLIIELYKYQAEEERRYIRETQQQGIALAKAKGKYKGGTLKYRENDPRLQLAF
                     NLFLTGSTDKEVEELTGINRRTFRRYRMKHGITNEVREQKNKSFS"
     gene            complement(10772..11767)
                     /locus_tag="ACGXWR_002225"
     CDS             complement(10772..11767)
                     /locus_tag="ACGXWR_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFK0803752.1"
                     /translation="MRPKLEDVAKRANVSKTTVSRVLNNRGYLSQKTIDNVYKAIEEL
                     NYQPNVVARQLFQKKTNIVGLLFPTVANPFFSELVEALEKKLYEIGYKVLIGNSMNNK
                     EKETNYLNQLLSDQVDGLIVGTHNQGIQEYKYQNLPIVAIDRVMNEDIPVVESDNYNG
                     GKLATKLLIAQGAKNIIHTNGPIDLQTPANRRRLAYEDTMKAYQLIPRTVTLDFNISY
                     VKKKQIFFQMFEDYPKIDGIFASNDIDAALILQVAKEKGLNVPADLLVVGYDGTLMTR
                     SILPDLTTVIQPINDIADTAVAILMKRINKEETKKEYILPVTLWMGKTSVKKKNN"
     gene            complement(11862..12734)
                     /locus_tag="ACGXWR_002226"
     CDS             complement(11862..12734)
                     /locus_tag="ACGXWR_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFK0803753.1"
                     /translation="MLIGSIEAGGTKFVCAVGDEDYRVQDQIICPTTTPRETLKKTVD
                     YFKQFDINALGIASFGPIEIRKNSPKSGYITSTPKVGWRNVNVLGYLQDELNVPMSWT
                     TDVNGSAYGEYIMSTLSNEKINSLVYYTVGTGVGGGAVVDGKLLGSFGHSEMGHTFVK
                     RHPDDIDFKGICPYHGDCLEGLVAGPTFEARFGKKGEDVSLTDPIWDVMAYYLAQAVI
                     QTTLIIRPDKIVFGGSVVNEKLLEKIRVNVNKLLDDYVEIPPLSKYITRPLIKNNGSA
                     TLGNFALGLNQLQE"
     gene            complement(12747..14174)
                     /locus_tag="ACGXWR_002227"
     CDS             complement(12747..14174)
                     /locus_tag="ACGXWR_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HFK0803754.1"
                     /translation="MTKRAIELTNTRYRLGYHVSAPSGWINDPNGFCYFDGYYHVFYQ
                     HHPYSAEWGPMHWAHARSKDLVHWESLPLALTPGDQEDEGGCFSGSAIEKNGVLYLFY
                     TGHHYYGDNDPDHFWQNQNMAYSTDGIHFTKYEKNPVIAKAPEDNTHHFRDPKVWKHD
                     EKYYMVLGSQEKDGLGRAIVYQSLDLLNWDYIGPISKAKEVLTEGFMWECPDFFELNG
                     KSILLLSPQGIEANGKDYLNLYETGYFIGDYDYETAKFIRGNFYELDKGHDFYATQTT
                     LSPDGRRIVMAWMDMWESPMPEKVDGWAGALTLPRELELIGDRLYMKPVRELEQLRVG
                     SGVETTVNLAGEIIIAQDASFKEALIDVLLTKSKNQEVKFSLKTKDEELINIFYSKDK
                     NECTLTRNGKNDPRYGTIQMCDRLSLRVFIDKSSAEIFINDGELVFTERYYTENQPSM
                     HLSVSEEAFVSSTIYHLKKDAISYE"
     gene            complement(14228..15502)
                     /locus_tag="ACGXWR_002228"
     CDS             complement(14228..15502)
                     /locus_tag="ACGXWR_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFK0803755.1"
                     /translation="MSKVNVFKNQSYLQSSATLLLFFASWGVWWSFFQLWLTSESNGL
                     GLSGSAVGTVFSANSLVTLILMFIYGTLQDKLYIKRNLLIFASVLATLVGPFFIWIYG
                     PLLDNNFNLGIIMGALFLSAGYLASVGVFEAVSERFSRLFGFEYGQARAWGSFGYALV
                     ALLAGFLFVKNPHLNFWAGSFFGSLLLLNLLFWNPKVEREANQNFNQEQAESNSIPSL
                     KEMFDLMKLPQLWTIIIFIVFTWTFYTVFDQQMFPGFYTGLFSTSANGEKIYGTLNAI
                     QVFCEALMMGIVPIIMRKLGVRNTLLLGVTIMCVRIGLCGFASTPLFVSCIKMLHALE
                     VPLFTLPMFRYFTLHFDTKLSATLYMIGFQIAAQIGQVILSTPLGILRDNVGYQPTFK
                     IISLIVLLAGIYAFFILKQDDRDVQGDPFIRG"
BASE COUNT         5213 a         2872 c         2238 g         5384 t
ORIGIN      
        1 aattttttct tgctgatctt tactaactat ttcattcccc agggctaact cgctcctcac
       61 tgattctgtg aaaaattggt aatccatttc ttgcattact aaaaacggcg atgacaaatt
      121 ttttttattt tcgattatct ttcctttggt agggcgaata atcttcatga gtattcttag
      181 taaggttgtt ttccccacac cgtttttccc taccaaacca ataacatctc caactttgac
      241 atcaaaattt atgtctttta gaatattttc ataagtaatt tcttcaactt ttaatacatc
      301 tgcacttacc ttttcgatat agggaacttc aatcgaacta ttaaaaatgt caaatttcct
      361 taatgcgtta ttgttttcag tttttaacaa ctgaatagtt gtagttttta cagttctatt
      421 tttaacaaat agaacttgat caattaattc tttcaaatag taaaaacgat gttcagctat
      481 aacaatagta aatcctttat tttttaaatc acaaagtaag tcagcaagtt tcttagtcgc
      541 tttgaagtcc aaatttgaag acggttcatc caatataatt aatttagagt ttagcgataa
      601 actacatcca atagaaattt tctgccgttc accacttgat agcgaaaaaa tgtttttatc
      661 taatatattt gaaagatcta ataattcagc taattcattg attcttttat ccatatgctc
      721 ttttgtaaat ccaaagtttt ccatcgaaaa tactaactca ctcgttgtat ttgttgtaaa
      781 gaattgtcct ctaggatttt gacttacgta gccaatattt tttgatatac tttcttgtgt
      841 taaggattgt agcgagttat tttcaaataa aatttcccca accaattttc cgtcataaag
      901 tcttggaata agtccattca ttaactttaa tagtgtggat ttcccactcc cagaagaacc
      961 agtaatcaat gtaagactgc ctttttttat tgaaaaatta aggtcaacaa gcgcttgttc
     1021 cttaacatcc ttatatgaaa aagaaacatt gttaaattca aacaattctt tcacctcaaa
     1081 tcaaaatact taagaaaaaa atagtaacgg aaaacaggat gatatagtct aataagctca
     1141 tgtttgtttt atagtaagaa cttcttttca caggagattc tatccccttt gttattgcat
     1201 tagcggtcat ttcttcagca atcatagttg cacgtataag aacgggaact aacagaaatt
     1261 ccaaatattg cagaggctga aaaaaagaca agcgaatgtt tctcattttt aaagattctt
     1321 taatcattct tatttcagaa cgataagtcg gaaagaatct gatcactact gtaatactta
     1381 acattatttt tttcggtaaa tgtatttttt ctaaagagga taataattca ttgctagtat
     1441 agacactaac caacaaccat gagatcatta cgaccggcaa cattcgaaat acaatatata
     1501 aggatgtccc aaaaaatata gtaaaaaact ctatcttgat agcatcaata attttcatta
     1561 ctaaaaacag aactgaataa atcaagatga aataaataca tgtctttatt ttacgaaaca
     1621 tcaatactaa aactgtagca ataatgaaac accccacttg aaatatattt ccctttccta
     1681 aaaaaataat gaccggaaaa aaaatattta aagtaatcaa ggttaacgga ttgatttttg
     1741 acactctttc acctccaaaa aataagatcg cactgttatc ttaagctgac aaaaatgcac
     1801 cgttattcag ataacagtgc gatcttatca aaaagcataa ctgagaacaa ttctcaatgc
     1861 aagctttttt ttaattaact cagtaattca atccacccag gaacagaaaa ttgatacaat
     1921 cttctggtta atagcatagt cttttctttt gaatagctat gcttcaatat atcatagaat
     1981 gtagcgtaga atgagtaaat gtagaagtgg atttcttctt cattaaagac taaattttga
     2041 ttgatcattc cgatagtctt taacttatct agacaacaga ctgtcttttt tgtcacaaat
     2101 gatgtaattt tttcaacaat atcttgatat ttggttccag ctgattggaa taaaaccaaa
     2161 tcgaatatac gtttattctc aaaaatataa ttaataaatg gatctaattc attgaagttc
     2221 tctctccaac ttttctctat atctatattt tctaagttta agaggtattt ggtaaactct
     2281 tcattataca tattaataag cgcattaata tgcggctgaa taatttcttc aaataacgct
     2341 tccttagaag taaaatgttt ataaaaagca cccgtagtta cgcctgcggt caagcacagt
     2401 tgccttatct tagtttgctg aaatccttct ttttcaaaat ggcttagtcc actttctatt
     2461 aatttttggt gagttgtaat ataatctctg gtttctatgg gtacttcctc ctaataagat
     2521 gaattaacta tattatctta cacaggactt gaagtttcaa tcgttaacgt ctattactga
     2581 actcattcct tagagctaaa ctaatgagaa agagcaaaat aactgataca aaaagcaatc
     2641 ctacaagaat taatagactc atctaaatca ttcacctttt ctaaaataat ccgagaaaga
     2701 tttaaaaaaa ttatatccag ctattagggt aagtcctatc ataatcactc caatagccat
     2761 tttcttatcc tccctaaaaa taaagtcttt tacttaaaac cttttttgta atcgtcaata
     2821 aattttttcc ctttatcagt taattgaaat cctatatcta aatagtcctc atatctaagt
     2881 ttagccagca tctcacttac agatgctgga ctaacactta gaacttttgc taaatcatta
     2941 ttttttaatt tcttttttct ttttgataat tcctgaattg ctagtaaata aattagtata
     3001 gtagtcgttt taatttgtac catacctacc ctccaaatta tttcgaaagg ccttcagcaa
     3061 ttttatccag gttccatttc atcatcgcat agtaactatc accatcttgt cctttttctg
     3121 caattgaatc agtaaaaatc gttgaataga taggaatatt ggtatctttt gatactgttt
     3181 tcattggtct atcgtccaca ctgctttcta cgaataagga gggaactttt gttgtgcgta
     3241 atttttcaac taagtgtttt atttgatctg gtgttccttc ttcttcagtg ttgatttccc
     3301 aaatgtaagc agaaggcaca ttatacgctt tcgagaaata tttaaagcat ccttcacttg
     3361 taacaatcat ttttttatca ttcggaattg aagcaaattt agatttagct tctttgtcta
     3421 gagaatccaa tttttcaata tacttatcta gattttcttt atagaatttt ttattatcag
     3481 gatctttttc cgctaactgt ttttcaatat ttttagcgta aataataccg ttttctaaat
     3541 ttaaccaagc atggggatct tccttacctt tctcactctg accctctaag taaataacat
     3601 ctatgccatc acttgctgca aaatagtctt tgttttcctc tttgttcgca ttttttacta
     3661 attttgtaaa ccaagcattt cctccagttt ccaagttaac accgttataa aaaatcaaat
     3721 ctgcttttga agttttttga acatcttcag gcaaaggttc atattcgtgg ggatctttcc
     3781 caataggtac gatactgtgt aaatcaattt tatcttttgc tatattttca gtaatatctg
     3841 ctaaaatcga attagtaact actaccttta atttttcgtt cgaagccact gtatctttgt
     3901 ctttactatt tgttgaacat gccccgaata taaaaagagc aatcaaaatc cccagacttc
     3961 ccagtactgc tttccatttt ctcatcataa ctttctctcc ttctttctta aaaatttttg
     4021 ttttggtgag attagaaaac taattacaaa taagaatgcc gctgttaaaa caatacttga
     4081 tcctgctgct atgttaaaac tataaccaat gaacaaacct agcaatgatg agcacgctcc
     4141 gactgtcgcc gaaataaata tcatagtttt taagctgttt gcatataaat atgctgtagc
     4201 agctggtgta attaacattg caacaattaa tatagttccc acactttgca tagctgttac
     4261 tgctactaaa gttaatagaa tcattaatag ataatgataa aaactgacat tcatccccat
     4321 tgcttttgcc attaatggat caaaagaagt gattaataat tctttaaaaa atagaacaac
     4381 tgtaaccaac actaaaacag aaacgccaat tgtaatccac ttatcaatat cttgtacagc
     4441 taaaatattt ccaaataaga tatgaaataa atccgttgag ctatttgcaa ctcctataag
     4501 gataactcct aatgctaaaa aagaactgaa agtaatacca attgctgtat ctccttttat
     4561 tacactattg ctttttataa aagtaataat gatagaagct aatagaccaa atacaatcgc
     4621 accaataaaa aaattaatac ctaaaatata agaaattgct actcctggca aaacagcatg
     4681 agaaatagca tcacccataa gagacattcc tcttaaaata ataaaacaac ctactgttcc
     4741 agaaacaatc cctataacta cagatgtaat tagagcattc tgtaaaaagt gaaagtcata
     4801 cagaccatta ataaaatttt gaagcatatt attccccctt gtatattaga gttagggttt
     4861 taaccttccg gttttgattg gataacccta tgaaccatcg ttattttaat ttggtattaa
     4921 ctcatttctt ttgagataat atatttattg gattgagagg ctaagccgtt ccccccttgg
     4981 gccattgaac ccgcactcga gagactggct cctctctctg ataagtggat tgcgtatgag
     5041 ttagatgttg aaagtcctta ctttactccg tatctcgtac aaggtagtga cgcttttcag
     5101 ttgagtggat ttcaatccaa aattcttttt ttgaaaggtc agatatacat gtacttttta
     5161 ggcattgata tcggtaaacg cactcacgtt gcttctatca tgaacgagga aggaaaggta
     5221 ttactaaaag gtttttcatt tcctaacacc actgaaggag cagagtcatt aattgagcga
     5281 atggtcgact attccggagc acccagtgac tttgttatag ggatggaagc cacggggcac
     5341 tattggctgt ccatcttttc ataccttcac gaatcagatt atttgattca cgttgtgaat
     5401 ccccttcaaa cagacggatg gcgtaaaggt acagaaatac ggaaacgaaa aaacgatatt
     5461 attgattctg ttttgattgc tgacttaatg cgctatggct catttgtcga aacggtctta
     5521 tccgatgaaa atgttttttc tttgaaacaa ctttctcgtt accgaactta tttagtaggt
     5581 acagcgagcg acttcaaaag aaaaattata gccgtattgg atcaagtctt tccagaatac
     5641 gcgacgattt ttaccaagca gggcgttttc ggaaaagctt ctaaagagtt attgctggcg
     5701 tttagtgccc cgatcgactt agaaaacatt tcctcagaaa ctttggccca atacttagct
     5761 gagttaagca ggaaccgaat caaggcagaa aaagcggacc aattgaagca agcagcttct
     5821 aactcctttg gagtaaaatt tgctcaagaa gcgttcacct tccaactacg ttcaatgatt
     5881 gaacaattaa aattcattga aagccaaata aaggaaacgg aaagagaaat caagcacata
     5941 atggacactt taaattctgt tattctcaca attcctggaa ttggtcctat aaacggtgcg
     6001 actattcttg gtgagatcgg agatattcaa aaattttcta acccgaaaaa actcgttgct
     6061 tacgctggga tagacgcttc cgtgacacaa tcagggcaat atgaggcaac gcataatgtt
     6121 atgagtaaac gagggtctcc atatttgcga aaagccttgt tttcggcggc tttagtagct
     6181 tctcaatgtg atcctgtttt tagtgcgttt taccagaaaa aagtttccga aggaaaacat
     6241 catctaactg ccttaggtgc ggtttctcgt aagctttgtt acgtgattca tgctattttg
     6301 actaaaaacg agccttatat aattgtttct gattagctat tgaacattca aaaaaactaa
     6361 tggtaagaag cttatttgtt gtaccctttt ttcggaatta tctgttataa aatatttttt
     6421 gatttggcta atttttactt gactctatat agttagtctc tccaataaat atagtatctc
     6481 cataggcttt ttttaaattc tcttcattaa atacagattc tacacttccg tgagcaatta
     6541 gatttcgatt caaaagaata atattatcaa aatacttctt taccttgctt aaatcatgat
     6601 gcacaattag cactgttttt ccctgatgtt tcaattcttt taacgtatcc ataattattc
     6661 gttcactaac taagtctatc cctacaaatg gttcatctaa aaatatgaaa tccgcatttt
     6721 gagcaagaca tcttgctaaa agtacacgtt gaaattgtcc tccagataat tctcctattt
     6781 gatgattaga atattttccc atatcgacct tttccaaagc ctttgaaact ctttgccatt
     6841 ctgcattttt aattctttga aaaactttca ttccggcata tgttcccata gatacacatt
     6901 cttttacttt tattggaaaa gtaaaatcaa tatcagcttt ttgctctaca tatgcaatct
     6961 tcaccagttt tttattgata tcttcattat taatggagac ctctccctga tgagggataa
     7021 tatttaacat tgctttaagc aatgtagatt ttccagcacc atttggacca ataatacctg
     7081 ttaaagcacc ttcttgtatt tttaaagaaa tctcgttcaa tgctaaaaaa tcgttataac
     7141 aaacattaag ctttttcact tctaacataa ctttctcctt ctaaatgata atgattatca
     7201 cgatcatatg gtatacaaaa attatatttt agtcaaccct aaattttata atttagattt
     7261 ttttctgttg ctgaagatta gaatgacaaa actatttgaa actacgcgta tagtaagtag
     7321 ctttcaaaat atataaaaaa ggagcgttct caaatgagaa catgctccta aaactacttt
     7381 attggcgtat ggaaaaatta tacttaaagt ggatagcggg ttgaataagt tgataagcat
     7441 caaaacattt ataaaaatta ttcaagacta tgtctgttcc atatacaaat atgaaaatca
     7501 gtaaactcca tttaactttt ttcgtagtgt gtctttttat acatgtttat cgttattaat
     7561 agtgaatagg aaaaaaccta tttttgatca ttgacaatta aatacaattt ttgaataacg
     7621 atccctgcta ttcgagctag aaactcaagt acgccatgac ctgattagcg acaaatactt
     7681 agagatttct ttttgttctg ggaaaacaaa atgccatgac aatagcagca aataatgata
     7741 cttccgtaag gctcgccgta aactggggag aggtgaaatt cctatgtgct tacccaaagc
     7801 aattcaaaaa ttctaatctt ttttaggaga tgattttata aaattgagag tctacttgaa
     7861 taaaaaacaa acctgtgagt ttctaggaat tgataataat actttagata agtggattcg
     7921 tatatataat tttccagtaa tcagaattga cggtatagtt cgctttgaca tagaggatat
     7981 caaagatttt atgaatacat ttaaaacaat ttgaaaattt cttctcgccg catatactaa
     8041 gaatagcgaa atatactgcc ttacttttta agggagtgag gaattttgcc tacaaaactt
     8101 tcaaatggga aatataaaac taatctgagg tatccaaaaa aattcagaga aatcactgga
     8161 attacatcag aaaagtatca aaaagtattt ccaactaggc aattggctat taaagccgaa
     8221 aatgcaatga aaaggaaaat tgaaacagtt ttaagagagg agaatgcaaa ttcactagaa
     8281 ttaaaaggaa aaataaaatt taaggaattc tatgaatcaa aatggcttcc tagatatgaa
     8341 ctaggtcaga ctactagatc aaaaagagct ccaagttacg taacaattag taatactaaa
     8401 gatatattcc gattgcacat ccttccaatg tttggtgagt atgcaatgaa ctatctaaat
     8461 tcaaatactg agataatatc agatgaatta acaaaaaaat cgaaagaata cgcaaatata
     8521 aaaattatca aaggatatgt ccgttctatg tttgatattg cagaaatact aaattatatt
     8581 gaatttaacc gaactaccaa aattattcaa tgtatcactg cacctaaaaa aattgcttta
     8641 gaagaaagaa ggatacggga aggtaatcaa gcattatcgt cagaagagct tattgcttgg
     8701 atagaagcag taaacactga cttgaataat cacttgctta ctcttcatga ctatactctt
     8761 ttcatgctta ccctatatct tggtgataga aaaagtgaga cgtatgcttt gcaatggaaa
     8821 tatatcgact ttgagaaaca aacggttcgc cttaaacatg ctttggataa atatcaaaaa
     8881 aagaaattta caaaaggtcg aaaggatacc gtaattcaag tacccgaaat tgtaatggca
     8941 ttactaagca aatggaaatc agtgcaagct gagcaattgt tgagattaaa aattaatcaa
     9001 acaccagatc agtatctctt tacctatact aaaccatccg gagaagtaaa ttgccctgtt
     9061 cacgctgatt acctaaacta tcgaatcaat tcaattaaaa gacgacatcc tgaattggct
     9121 catttatctc cacataagct tcgtcatacc tatgcaacta tagctagaca aggcggagca
     9181 aatatgaatc aaatatctag tgctttaaca cactcagata tttctacaac gagaatatac
     9241 gtaaatacac cagatgtagt agataaaact gtttttgaag cctttcagag aggattgaat
     9301 aaatgtgatt agtatgtgtt cttaaatgtg ttcttaaaca agaaaaagac acttttcaaa
     9361 caattgaaaa gtgccttgaa acattgatat ataaataata ttaacgttta gagaattgag
     9421 atgctttacg agcctttttg agacctggtt tcttgcaaaa ttatattagc ctcaactgaa
     9481 agatttattt ttttgctccc taacttcatt agtaatacca tgtttcattc gatatcttct
     9541 aaacgttcta cgattaatcc ctgttagctc ttcaacttct ttatctgtag atccagtcaa
     9601 aaacaaatta aatgctaatt gaagtcgcgg atcattctca cgatatttta gcgtacctcc
     9661 cttgtatttc ccttttgctt tagcgagtgc aattccttgt tgttgcgttt cgcgaatata
     9721 ccgacgttct tcttcggcct ggtacttgta tagttcgata attaagttat taagtaatcg
     9781 acgtaaatta tcatcagtga tacctgttaa cgctggcaaa ttcaaaactt ccagtgtagc
     9841 tttcttcagc tgaattaaat tcatcgtttc tgttagctct ttattatttc gtccaagtcg
     9901 ttttaattct gtcacaacga caatatcacc ttcacgtatg aatttcatca tttcttgaaa
     9961 tccttctcga ttggtatctt tcccacttgc tttatcacta aaaattttat cacactctga
    10021 taataattct aattgtcggt ctaaattttg atctaagctg cttactcgag catacccaat
    10081 tttcgccata ataaaactcc tttaaaattc tgaaatccgg atcattttta aattctgttg
    10141 cccaactctg ttgtcatttt tctagataaa tggcataaat tttcagcgct aagtgacaaa
    10201 agcaactaat ttttcatgat agatttttaa atatctcaat ctatctccaa aattagttgc
    10261 ttttgtagct atagttgact atgaatatga caaataatta gaaaaaactg tgccaattaa
    10321 atataaaaat gacactcatt tacattcaat agaacaccaa gagcccaaca gggtatactc
    10381 tggtgtcctt ttaaaaaagt aactttctga cctaattaat tgagctacta aaaaagctat
    10441 gaaatgagga ataaaaaagg gatcaaaaac ttttaagttt ctgacccttt tgagttctaa
    10501 ttatttcttc cagaacgaag aatgttatct gctttatctg caattgattc tgttagaagg
    10561 actgaaaaat ttatgccagc ccttttgcct agcttatccg cccattgagg aattgttaag
    10621 gtttttctga caagttctat gtctttcaaa tatttggcaa catctacaca gattaaaagc
    10681 atgattttgt atcatagtct attataagag atttaacaat tttttatatc acgaattaat
    10741 aatgaaatta tcattgatag tctttataaa tttaattgtt ctttttcttt actgatgtct
    10801 tccccatcca taatgtgaca ggtaaaatat attccttttt tgtttcttct ttatttattc
    10861 gtttcatcaa aatagcaaca gctgtgtctg ctatatcatt aattggttgt attactgttg
    10921 tcagatctgg taatatactc cgagtcatta aagtaccatc atatccgact actaataaat
    10981 cagctggtac atttaacccc ttttcttttg ctacttgtaa tattagggcc gcatcgatgt
    11041 catttgaagc aaaaatacca tctattttag gataatcctc aaacatttgg aaaaaaatct
    11101 gttttttctt tacataagaa atattgaaat ctaatgtcac agttcgtgga attaactgat
    11161 atgctttcat agtatcttca taggctagtc tccgacgatt agccggagtc tgtaagtcaa
    11221 ttggaccgtt tgtatgaata atattttttg caccttgtgc aattaataac ttggttgcaa
    11281 gttttccacc attgtagtta tcggattcaa caactggaat atcttcattc atcactcgat
    11341 caattgcaac aatcggtaaa ttctgatatt tatattcctg aattccttgg ttatgtgtac
    11401 caacaattaa accatctact tgatcagaca ataactgatt taaataattt gtttcctttt
    11461 ctttattatt catcgaattg cctattaata ccttataacc aatttcatat aacttttttt
    11521 ccaatgcctc aacgagttca ctaaaaaaag gattggctac tgtaggaaat agtaacccga
    11581 caatgttagt tttcttttga aataattgac gcgctacaac gttcggttga taattgagtt
    11641 cttctatagc cttataaaca ttatcaatcg ttttttgact taaatagcca cgattgttta
    11701 atacacgtga aacagttgtt tttgatacat ttgctctttt ggcaacatct tctaattttg
    11761 ggcgcattct cttgtctctc ctaaataatg caataattaa ctatcgaaaa aaagaactct
    11821 atagaactac tatacctgat aatcgatatt ttttctatgt tttattcttg taattgattc
    11881 aagcccaaag caaagtttcc tagtgttgcc gatccattat ttttaattaa aggacgcgta
    11941 atatatttac ttaacggtgg tatttccacg taatcatcca ataatttatt aacattaaca
    12001 cgaatttttt ctaacaattt ttcatttact acgcttccac caaatactat tttatccggt
    12061 cgtataatca atgttgtttg aatcacagct tgtgctagat aataggccat tacatcccaa
    12121 ataggatccg ttaaagaaac gtcttcaccc ttttttccaa aacgtgcttc aaacgttggt
    12181 cccgcaacta agccttctaa acaatcacca tgataaggac aaattccttt aaaatcaata
    12241 tcatcaggat ggcgttttac aaacgtatgg cccatttctg aatgaccaaa cgatcctaat
    12301 agttttccgt caacaacagc tccaccacca acgccagtac caacggtgta ataaactaat
    12361 gaatttattt tttcattcga taaagtggac atgatgtact ctccataagc tgatccgttc
    12421 acatccgttg tccaagacat tggaacattc agctcatctt gtaaataacc taacacatta
    12481 acatttcgcc atcccacctt tggtgtagac gtaatatatc ctgattttgg tgaatttttt
    12541 cgaatttcta ttggaccaaa tgatgcaata cctaatgcat ttatatcaaa ctgtttaaaa
    12601 tagtcaacag tttttttcaa tgtttccctg ggggtggtcg ttggacaaat tatttggtct
    12661 tgtactcggt aatcctcgtc tcccacggca catacaaatt tagtcccacc tgcttctatg
    12721 ctaccaatta acatcataaa acctccttac tcgtaagaaa ttgcatcttt ttttagatga
    12781 taaattgtac tcgagacaaa agcttcttca ctaacactca aatgcatact tggttgattt
    12841 tctgtataat aacgctctgt aaaaacaagc tcgccatcat taataaaaat ctctgccgaa
    12901 cttttatcga taaacactcg aagtgataat ctatcacaca tctgaatggt tccatacctt
    12961 ggatcatttt tgccgttacg agttaaggta cattcatttt tatccttaga ataaaaaata
    13021 ttgattaact cttcatcttt tgtttttaat gaaaatttga cttcttgatt ttttgattta
    13081 gtcaatagta catcaattag agcttctttg aatgaagcat cttgagcgat tattatttct
    13141 cctgccaaat taactgtcgt ttcaacgccg ctgccaactc gaagttgttc taattctctc
    13201 acaggtttca tatacaaacg atctccaatt aactctaatt ctcgaggaag cgttaatgct
    13261 cctgcccatc cgtctacttt ttcaggcata gggctttccc acatatccat ccaggccata
    13321 acaatacgtc taccatctgg agataaagtt gtttgtgttg catagaaatc gtgtccctta
    13381 tctaattcat aaaaatttcc tctaatgaat tttgctgtct cataatcata atcaccgata
    13441 aagtagcctg tttcatatag atttaaataa tcttttccat ttgcttcaat tccctgaggg
    13501 gataataaaa gaatagattt tccatttaat tcaaaaaagt ctgggcattc ccacataaat
    13561 ccttctgtaa gtacttcctt cgctttagaa attggtccaa tgtaatccca atttaataaa
    13621 tctaacgact gataaacaat agcacgacct aatccatctt tttcttgact acccaaaacc
    13681 atgtaatatt tttcatcgtg tttccatact tttggatctc tgaaatgatg tgtgttatct
    13741 tctggtgctt ttgctattac aggatttttt tcatatttag taaagtgaat gccatccgta
    13801 ctatacgcca tgttttgatt ttgccaaaaa tgatctggat cattgtctcc ataatagtga
    13861 tgtcctgtat agaacagata caacacacca tttttttcaa tagcgcttcc tgaaaaacaa
    13921 ccaccttcat cttcttgatc tccaggagtc aaagcaagtg gtaaagattc ccaatgaact
    13981 aaatccttac ttctagcatg tgcccagtgc attggtcccc attcagcact atatggatga
    14041 tgttgataaa acacatgata atacccatca aaatagcaaa atccatttgg atcattaatc
    14101 catcctgatg gtgcagacac atgatatccc aaacgataac gtgtatttgt taattctata
    14161 gctctttttg tcataatata ttcgctcact ttctagataa aattgttttt tattctgttg
    14221 gtttccatta tcctcgaata aatggatccc cttgaacatc tctatcatct tgtttaagaa
    14281 taaagaatgc atatatgcct gctagtaata caataagaga aataatttta aatgttggtt
    14341 gatagccaac gttgtctctt aatattccca atggtgttga taaaatcact tgcccaattt
    14401 gagcagctat ctgaaatcct atcatataga gggttgctga tagctttgta tcaaaatgaa
    14461 gtgtaaaata gcgaaacatt ggtaatgtaa ataatggtac ttctaaagca tgcaacattt
    14521 ttatgcatga aacaaataat ggtgtcgagg caaacccgca caatccaatt cgtacacaca
    14581 taatggttac acctaataac aaagtatttc gaacccctaa ttttctcata atgattggaa
    14641 caattcccat cattaacgct tcacaaaata cttgaatagc attcaatgtc ccatatattt
    14701 tttcaccatt agctgatgtt gaaaacaaac cagtataaaa tcccggaaac atttgttgat
    14761 cgaataccgt ataaaatgtc catgtaaaaa caataaagat gattatcgtc cataattgag
    14821 gcagtttcat tagatcaaac atttctttta aagaaggaat actatttgat tcagcttgtt
    14881 cttgattaaa attttgattt gcttcccgtt caactttagg gttccaaaat aataaattta
    14941 acaatagtaa agaaccaaag aaagatcccg cccaaaagtt taaatgagga ttttttacaa
    15001 ataaaaatcc tgccaaaagc gctaccaagg cataaccaaa tgatccccac gcccttgctt
    15061 gtccatattc aaagccaaat aaacgactaa acctttctga cacagcttca aaaactccta
    15121 cagaagctaa atatccagct gacaaaaata gcgctcccat aataatgcct aaattaaaat
    15181 tgttatctag caatggccca tatatccata taaaaaatgg tccaacaagt gtcgctaata
    15241 cagaagcaaa aattaataaa tttcgtttaa tatacaattt atcttgtaat gttccataaa
    15301 taaacatcaa aattaaggta actaacgaat ttgccgagaa tactgttcct acagcactgc
    15361 cagataaccc taaaccattt gattcagatg ttagccaaag ttgaaaaaat gaccaccaaa
    15421 caccccaaga agcaaaaaat agtaataatg tagctgaact ttgtaaataa gattgatttt
    15481 taaatacgtt aacttttgac atatttttat cctccaacga tatatttgta tcccctttca
    15541 tgataaccgg ttaacatttt tagaaaagga cttgtactcc taaaattata aaagaaatcc
    15601 gcttacatgt caaccggtta ttctatttgg ataatgccat ataatgtcac aggatatgac
    15661 ttttattggt gtgtcgcttt tcttttttaa tggcactatt ttttata
//
LOCUS       DAYNVV010000062        15413 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.065, whole genome shotgun sequence.
ACCESSION   DAYNVV010000062 DAYNVV010000000
VERSION     DAYNVV010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15413
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.065"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(41..964)
                     /locus_tag="ACGXWR_002229"
     CDS             complement(41..964)
                     /locus_tag="ACGXWR_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RodZ domain-containing protein"
                     /protein_id="HFK0803756.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(1703..2989)
                     /locus_tag="ACGXWR_002230"
     CDS             complement(1703..2989)
                     /locus_tag="ACGXWR_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFK0803757.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(2982..4250)
                     /locus_tag="ACGXWR_002231"
     CDS             complement(2982..4250)
                     /locus_tag="ACGXWR_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFK0803758.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            4502..4963
                     /gene="mscL"
                     /locus_tag="ACGXWR_002232"
     CDS             4502..4963
                     /gene="mscL"
                     /locus_tag="ACGXWR_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HFK0803759.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(5022..5468)
                     /locus_tag="ACGXWR_002233"
     CDS             complement(5022..5468)
                     /locus_tag="ACGXWR_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFK0803760.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(5561..5806)
                     /locus_tag="ACGXWR_002234"
     CDS             complement(5561..5806)
                     /locus_tag="ACGXWR_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HFK0803761.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(5921..6499)
                     /locus_tag="ACGXWR_002235"
     CDS             complement(5921..6499)
                     /locus_tag="ACGXWR_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFK0803762.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(6576..7106)
                     /locus_tag="ACGXWR_002236"
     CDS             complement(6576..7106)
                     /locus_tag="ACGXWR_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HFK0803763.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(7110..7970)
                     /gene="rlmB"
                     /locus_tag="ACGXWR_002237"
     CDS             complement(7110..7970)
                     /gene="rlmB"
                     /locus_tag="ACGXWR_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HFK0803764.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(7963..8358)
                     /locus_tag="ACGXWR_002238"
     CDS             complement(7963..8358)
                     /locus_tag="ACGXWR_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HFK0803765.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(8355..9767)
                     /gene="cysS"
                     /locus_tag="ACGXWR_002239"
     CDS             complement(8355..9767)
                     /gene="cysS"
                     /locus_tag="ACGXWR_002239"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HFK0803766.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(9764..10300)
                     /gene="epsC"
                     /locus_tag="ACGXWR_002240"
     CDS             complement(9764..10300)
                     /gene="epsC"
                     /locus_tag="ACGXWR_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HFK0803767.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(10386..10625)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(10622..12082)
                     /gene="gltX"
                     /locus_tag="ACGXWR_002241"
     CDS             complement(10622..12082)
                     /gene="gltX"
                     /locus_tag="ACGXWR_002241"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HFK0803768.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(12252..13409)
                     /locus_tag="ACGXWR_002242"
     CDS             complement(12252..13409)
                     /locus_tag="ACGXWR_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HFK0803769.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(13443..14813)
                     /gene="radA"
                     /locus_tag="ACGXWR_002243"
     CDS             complement(13443..14813)
                     /gene="radA"
                     /locus_tag="ACGXWR_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HFK0803770.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(14876..15403)
                     /locus_tag="ACGXWR_002244"
     CDS             complement(14876..15403)
                     /locus_tag="ACGXWR_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFK0803771.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         4037 a         3375 c         2774 g         5227 t
ORIGIN      
        1 atacctacaa gtaaacagat gcgtaaacta atttatacga tcattctgcg tattgaagag
       61 taaggttcac attttttgga ctctgattgt tttcccctgg attaactggt acggattctc
      121 cattcgcttt gatcgttgca ttgcttgctg caccaatcgt gatggtcgca tttgttgctg
      181 tttccggtaa cacggtactc tgtgtttcat ttgctgccag tgtcccttga taaacatagg
      241 cattgtctac tagcacacct aaccatacac gattgacagc agtaaattca agggttacag
      301 gcttggtagc gtctgtgata tttactgcga tggcactgcc agaatcttct cctgtagcta
      361 ttgccatttt cttttcttca cttgattttg ttgttgattc tactgtagaa gactctttgg
      421 tctgcgtgct ttgctctgag gaagaggact cctcgactga tccttctact ttaagcgaag
      481 aagctgtgtc tccgattatt ggatcagctt gacgatcttg ccaagtcata tagcccacga
      541 caacgacaat cgccaaagca accaatccta ataaaatgac aggaagactt gtccaaaagc
      601 gacttggatg cgattcttcc tgatgcattg cttttctaga agtacttact gtttcaggct
      661 gcggacgttc agggaccgat cctgtcaatt tgcttttccc atcaaaaaca tcgactaaat
      721 ggtctccatc ttctcctaca gcttcagcgt attgccgaat aaatgcccgc acgtaaaatt
      781 taccaggcaa ttggtcaaaa tcatcattgt cgattgcttc caaataacgt ttttgaattt
      841 ttgtaatctg ctgtaattca tctaaagata tttttttatt caggcgtgct tgccgtaatt
      901 tttctccgat ggtttcaaaa gccactcgtt catcttctcc agtctgtttg attctccgaa
      961 gcatctgctg ttgcaacgaa agacgttatg tttgggtgct gtgacaaaag tcatgtcaca
     1021 gctccttttt tccgaataaa cattgttctc ctgccaactc ctcggtcaca agtcacaata
     1081 tccaataaat ataagaagct gttttttgaa cttgttcctt gtgactcgga gttaaacggc
     1141 aggctcacga cctctttctt aaacggtgtt caatcagctg ttcctcggta ttagctcaaa
     1201 aaccggcaaa atataaggag atatttttcc gtatgtttct ctaatactca ggtcaaaacg
     1261 ctgatttcac aacctcttcc ttaaacggtg ttcaaaagct tgcatctgcg gtaataagtc
     1321 caaccaagtt aaaaacatta agaagctgtt tttacttggc tgttcttatt acttgatgca
     1381 gggcagcttt ttcacaacct cttggtacac ggtgttccag aagtagcttc ttcggcaata
     1441 agccgaaata tcacaaaaat ttgagaagca attttcgtaa attccttctt atttcttgaa
     1501 gctgaccact tctgtcacaa cctctttgat tacttcgttt gattttattt taatataagt
     1561 tgattaaaag agagcatgat ttgttttatt ttctcactaa tttttccaac acaactaaga
     1621 ataccataaa agctgatttt ggaggaggtt cctactacaa gtctaaaacg aaatttaaga
     1681 cttttcctca taaaatactg gtttattttg gtctcatgta aaactcgctg aaggcctctt
     1741 cacttataaa tgcttcccca gctgccagta cgtctttcat ttggatcgaa tcgatgattt
     1801 caggaagatc aaataaagtt cgatcgccaa ataaactttg cgtaaattga ttggcaatat
     1861 attcgatcga atttaatgat tggaaatatt gtccaagcat tttcttcttc agcaaatcga
     1921 gatttgtttc tgacacttcc ggatcatcag cgaatccaag aatgatttct ttgacttttt
     1981 ctgctgcttt ctctggttcg tccgtatctc cgctgaagtc cgcaaagtga aattcacgat
     2041 ccaagctgaa ttcaaaacca aagctgtcat cgataattcc ttgattgtac atcgctagat
     2101 agtttcgaga agtattgcct aaaatcattt ggaacaacag attgattgct gttttatagc
     2161 gtaacagttc tgttccttct tgcggcaatg tgtctaatcc tttaatacca agtacaaatt
     2221 tatctcgtgt aatggctgct tccaatgcac tttgtttgat gatttctttt gtgttttcag
     2281 ggaaataacg tacaatttct tgctttggag ggaaattttt tgcttcttgg ttttcccgaa
     2341 taagtttcat caatttctca ggctccatct taccaactac aaataaaacc atattgcttg
     2401 gctgataaaa cgtccgatag cacgtataca agtcttgagc tgtgattttg tcgatacttt
     2461 caaccgtgcc cgcaatatcg atatgcaatg ggtgtgtagg atacaagtta tttagtatgc
     2521 caaaaaacat ccgccagtta gggtcgtctt catacatttg gatttcctga ccgatgattc
     2581 ctttttcctt gtttacagtt tcttctgtga agtaaggtgc ttgtacaaaa tcgatcagag
     2641 tcgtcagatt cttttctacc tgatccgtcg tagaaaacag atagctggtt ttcgtaaaac
     2701 ttgtgaaagc attggcggaa gctccttgtt tcccaaataa ttgaaagaca tcaccatctt
     2761 ctttttcaaa caacttatgt tctaaaaaat gggcaattcc atctggaact ttcacctttt
     2821 ctttttcacc atagggaata aattcgttat cgatcgaacc ataattcgta ctgaacaaac
     2881 catatgtctt gtgatagtca tttttaggca acaaatacac ggtcaaaccg tttggcagta
     2941 cttcatgata aagtgtttca ttgatttgct catattctgt tttattcatt tgcatttcct
     3001 cctgctaaaa agaagattgc ctgcaattcg atttgctcag ctacttgttg tatctctttg
     3061 atcgttacgc tctccatacg tttcaaccat tcttcatcag ataattttgt ttccggcagc
     3121 cagctgtcca aaaaagaagc ttcgattgcc gcttgcggag agtctagaga aagcagatat
     3181 tggtttctca gcattgcttt tgtctgagac agttccaact ctgttatttc accatttcgc
     3241 aaactttcta attgctcgtg aatcagatga agtacttgat ttcggttctt ttcatcgata
     3301 ccggtttgga cactcatgaa tcctcggaac gtatccacgc tactagaggc ataataagct
     3361 agactttctt tctctctgac attcatgaaa agtttagagt gaggaaaacc gccaaataaa
     3421 ccgttaaaga ccattagcgc aaaacgttct ggttcatcgt aatacacatt tgtctgataa
     3481 gctaggttca gctttgcttg aacgattggc tcacgtactt gtcgttcctt cacgatattc
     3541 acttgaggtt gggtataaaa cagatctgga taaactgttt cccgcgactc aaatggtaat
     3601 tgcccaactg cttcagctgc tttgtccgga tcaacatcgc cgacaacaaa aatgtcgatt
     3661 tgatcatttg ccatcatttc ttgatagtag gacgctagcg aactagcagt gatcttgtcc
     3721 aaatcttcga ctacgcccaa ccctgggatc ttttgttccg ggctgttttc aaaataaagt
     3781 tcttgcaagg cataggaagc aaaagtttgt ttatcttcct tcaaactttc caaatataga
     3841 cgcagattgt tcttttccaa gtcaaacgtc aactgatcaa actgatgatt tttaatattt
     3901 ggataaaata aaacctcttt taaaaaatct accgcttgag aaaaaaggtt tggatcattg
     3961 acatattcac cattcacaaa actgatccct gcgtttagcc aatgtaaatt tccttttttt
     4021 ctaactgata atccaaagct tgcgccataa agctctgcaa gttgcgcact taactttgtc
     4081 tgatccggat aattcaaact atttgtttcc aacatgctgc tgagaagtga acgtttcgtg
     4141 atgacttctt gttgcagacg cgcagtaaaa cggataaaaa tccggatcgt tttgtattgt
     4201 tttgttggta agacatgaag attcacgcct tctgccaatt gatacaccat atttatatgc
     4261 tccttttcac agttgattgc ccgcttactc ttttaatggg tcaacctgcc ttttttactt
     4321 attcctctgc ttgaaattta taagttcagg caattcgccg ttttttctaa atgatgttac
     4381 actttatagt atagcataga tgttttttat caaaagaaac agacggctaa aagcgtatat
     4441 tgttttttta ttttttattt ttcgatatac taaagacaaa taaaagaagg gagggtcatt
     4501 catgatcaaa gaattcaaag agttcatcat gcgtggagat gtcttggatc ttgctgtcgg
     4561 cgttgttatt ggtagtgcgt ttacaagcat cgtaaaccaa gtggtgcaag gcttgatcac
     4621 accactaata ggttggtttg tcgcaatgat cacaggtact tctgatttag aaggagcact
     4681 ttcaattctt gactggtcgc cgacaaaagg cgtcacattt gcgtttggta acgttattag
     4741 tgctatcatt acatttctga tcactggttt tgtcttattc ttagttgtca aagcggcaaa
     4801 ccgtgcgaag aatttacgct ccaaagaaga gcaagtggaa gtggaagaaa ctcctactgc
     4861 agaagattat cttagtgaca tacgcgatct tcttgccaaa caagtggcag aagacaatac
     4921 acatccagta gagcaaacaa atctttccga tacttctaaa taataaagaa tctaaaaaaa
     4981 agaaagccga ttttcagtgt cggctttctt tttttagatt cttaacttgc tacttgttcc
     5041 tttttcatgt cgatatgtgg aatatcatct tccaaataca catctgagat tgccttgaat
     5101 ccaaacgact cataaaaagc ttgtaggtat tcttgtgcgc cgatcacgat tggtttttct
     5161 ggaaaatttt tctggatcat gttaatcgtt tcttgaacaa tctttcttcc taaaccatct
     5221 ttacggttgt cctgatgaac aaggacacgt ccaaaatgga tactctccgc ttcttcatat
     5281 actcgcgtgt aggcaaggat cttcccatca gtatcttgaa aaaacgtatg ccaagcttgt
     5341 ccatcaatgt catcaacttc ttgataagga cactgttgtt ccacaacaaa aactgcgatt
     5401 cgttctttga cgatcgcgta aaactctgct gttgacaatt cttcaaattt ctttacctga
     5461 tattccacta agcaaacgcc ccctgctttt ttattcttag cataccgatt cgcacacaaa
     5521 aaagcaaacg aaccttacga atctcaggct cgtttgcttt ttaaactgct tcagttaaaa
     5581 attcgatctc aactgtccga gtaagtacat ctgaatagct gtaagatact cgttcaaaag
     5641 aattttcttc aggatccaaa tcaacaacga atactgaagg ataggtttct gttaaaacgc
     5701 cgcggcgttc tgtttgacgc tttcttcctg tctgagcaac caacatgatt gggctgccga
     5761 tacgaccttc taaatctttc ttgattgaag ctaaagttgt tggcatacag ttcacctcta
     5821 ctatcaacta taccacatat ttttaaaatt ttcaagttta ccataaaaaa aaaagaaatg
     5881 caataaaaat aaataagaag ctcattaaga tttttctaaa ttattcctca ttataaaatt
     5941 tcaagtgttt ttttattttg agttttactc tcccgtaagc gctcattact tgcttgtgat
     6001 ccattgctaa acattcagcc atgtctacaa aatcaacgcc ttgcatataa taatgaaaaa
     6061 ttttagcttc tatttttgaa aactggattt cgcaattttc gattgcttct tttaataaaa
     6121 gatgctgaat cgctaaaggt tcttgcaatg tgatctctgc taaaaagtct ggtccttctg
     6181 tctctatttt ttggtcgatt gagacttcat ctttttgatc acgacgcttc agcgcgttct
     6241 gcttcctcaa cagagaatag atttgattgc ttataatgct tttataataa cttccaaagc
     6301 taacaccttt gcttttttcg taagttctca atgcctgata taaagcgatc cttgcttctt
     6361 gttcccaatc ctcagaaaca taatttctta aataataggt gtttttcaaa cgtagtaaaa
     6421 gtggaaaata tttttgatac agggcagcaa atgcttcttc gtcaccatta cgtgcagcgc
     6481 gcaataactc ctcagacata aaataattcc tccataaatt cgtttatgga ggaatcttat
     6541 catcaatgat tcatcgaact gattagaacg atatgttatt tattttttct cattaaatcg
     6601 tccaattttt gggacaattt ttttaactgc tcttcattcc atggagaatt acgtcggaaa
     6661 tcaataaaat gcatatcttt attttcttgg gctattgttt tttccgtttt ttttatcgtc
     6721 ttatataatt cataagcaga agttcgtaat gctccttggg aaaagatcat ccactgttct
     6781 gctaaatcgc ttgtcgccac tgtcacttgt gtcaaacggt cattcagctg accagcgatt
     6841 ctctcgatat aactgtcagc cgtttcgtct tctttcgtaa aaacaacatc caactggtat
     6901 ttcttataat tttgttggat gcccggaact agttgggcat cgaagacaac gatgacttcc
     6961 attccttcat atttcgcata atttgataaa cgatgtaaaa gagcttctct tgcatccgcc
     7021 attttgtcct gctttttaag ctggacaagt tccggccacg aaccaatcat gttgtagccg
     7081 tctacaatca acagctgttt tttcatggtc tactccccct gacgttggga aaaagcctga
     7141 tacataagca aaccagcagc aacactggca tttaagctct ggacgtgccc ggtcatcggg
     7201 atcgtcagca attcatccat ttcttttttc aatcctggac tcattccttt gccttcatta
     7261 ccaatgacta aagcaattga tcctttggca ttccattttt ggaagtttgt gccggtcata
     7321 tctgtgccaa atacccaaaa tcctgtttct ttgagctgtt gcacagcttg taccaaattc
     7381 gtcacgcgtg caacagggac atgttcgact gccccagtgg aagtctttgt tacgataggt
     7441 gtgattccaa ctgctcggtg ttttggtatg atcacaccat cgacgccact tgcgtctgct
     7501 gtccgtaaaa tcgacccaaa attgtgtgga tcttcgatgc tatccaaaat caaaaagaag
     7561 gggtcttctt ttttctcttt tgttcgttca atcagttggt caagggataa atattcataa
     7621 ggtgtaatcg caagaacgac tccttgatgc acgccgtgat cgctcaaagt ttctaatttt
     7681 tgtttaggaa cccatttgac tggcacagct tgttcacgtg cgatttcttt cagttcttct
     7741 actttttctc ctcgtgaatc ttcttgaaga aagagtttat tccctcgccc ttgttgtagc
     7801 gcttctactg cggcatggtg cccaaagacg aaattatctt ctaatgcttc ttcattttga
     7861 tcagaaactg actgatttcg tccagtttgc tttttatttg aatatctatt ttgttttttg
     7921 tcttcaaatc cacgtttcga ttgatgtttg tttgttcttt ctttacccat ttttttcacc
     7981 aactttctga atacaccagc ggatcaattc ttccatccgc tcggtttgtt ttgtcaaatg
     8041 cagatagccc atgagcgctt cgaaccctgt tgcgacccga tacgtcgtaa catcagcatt
     8101 ttttgcgctc gtatggcttt tagcatttct tcctctgcga taataaagtt cttcttcttc
     8161 tgtcaaaaga tgttcttcca gcatttgctg aatcaaaaag gcttgtgcat tcgcagaaac
     8221 ataattcgtt gccgcacgat gcagcttatt gggttttgtt tctccttgat caatcaggtg
     8281 gtcacgaaca tagatttcgt aaatcgcatc tccaacataa gccaaggcta aaccgttcaa
     8341 ttgtgtgtaa tctctcatgc ttctcttctc catcgggttc cttgcggtgt atcttctaat
     8401 aagatccctt tttctttcaa caaatcacga atttcgtcgc ttcggacaaa atcacgattg
     8461 cttcttgctt gatttcgttc ttcgatcaat tgttcaatct cttcatctaa taactcttct
     8521 gctgtaaata aaataccgaa gatcgaaagc cattgcgaga ataaagcttc tccttgtgcc
     8581 aagacagcgg cagaaacttt cggctggtct agataagtgt tcagccactt agcaagctca
     8641 tagaccactg tgatcccatt tgctgcatta aaatcatcgt ccatttcttc gatgaatcgc
     8701 tgttctaaat tttctaacaa agcgatttta tccgcatcat ctgccaaatt ctctgaggca
     8761 gtttcttggc ggaatttcaa attgtcaaac gtattcttca gtcgttgtaa attggtggct
     8821 gcttctttca tcgtcgtttc actgtagcgg atcggacgac ggtattgtgt ggtcgccatg
     8881 aagaaacgca agacttgtgg atcaacgttt ttgatcattt catgtacagt gatgaaattc
     8941 cctagagatt tactcatttt ttcatcgtct tcgccaatcg ttacatagcc attgtgcatc
     9001 cagtaattag cgaatttttt ccctgttttc gcttcacttt gtgcgatttc attttcatga
     9061 tgaggaaatt ctaaatcttg cccgccacca tggatatcga tcgtttctcc taaatgtttt
     9121 gttgccataa cggaacattc aatatgccaa ccgggacgtc ctttgcccca tggtgaatcc
     9181 caagaaatct cgccaggttt tgcttgtttc cataaagcga aatctaatgg gtcttctttt
     9241 tgctgctgtt cttcccctgt acgctgactt gctccgactt ccagttcatc gatggattgg
     9301 tcacttaatt tcccataatt ttcaaattta cgggtacggt aatacacatc acctgaagat
     9361 tcataagcat agcctttttc aaccaacact tgaataaatg ctaaaatatc tggcatatga
     9421 tccatgactc ttggatgcag tgtagcaggc tcgacattca acgctttcgt atcttcttca
     9481 aatgctcgga tgaaacgatc agcaacttct ggtgctgtaa tacctaattc gtttgctgta
     9541 cggatgattt tatcgtctac atccgtgaaa ttcgatacga aatcgacttt atagcctcga
     9601 tattcaaaat agcgtcgaat tgtatcgaaa gcaatggtgc tacgagcatt tccgatatgg
     9661 atataattat acacagtcgg tccgcagaca tacataccga catgtccctt ttgtataggg
     9721 atgaattctt ctttttttct ggtcaatgta ttgtagattt ttatcattct gatctcctca
     9781 ctttttctcc tttgattcga acgacttttg ctggtactcc taccgctgta gcgtcgtctg
     9841 gaacatcttt caacacaacg gcacctgcac cgattttggc gttttttccg atcgttaccg
     9901 gtcctaatat ctgcgcattc gcagagagca tggctccttg tttaacagtt gggtgtcttt
     9961 tacccgtttc ttttcctgtg ccgcctaatg ttacgccatg gaataaaatc acatcgtcct
    10021 cgatttctgc ggtttcgcca atgacgattc ccattccatg gtcgatgaac acgccagttc
    10081 caatcgttgc tcctggatgg atctcaacac cagttaggaa acgccagaat tgagcattga
    10141 tcttcgccaa taaaaagagc cggtgctgat ataaaaaatg agagaaacga tgccaaaaca
    10201 aggcatgaaa accagggtat gtcaaaacga tctcagctgt cgaacgtgca gccggatcgt
    10261 ttctctttgc tgcatcaatc gctcgggtaa accaactcat gactttccac tcctttcgta
    10321 agaattttat gtaggaaatc atcttcttat aaagaaaaga agcgcctttt aaataagttt
    10381 ccttatcaaa agacgctttc cgcgtggttc cacttttctt cataatcaat gattatctct
    10441 gacagctaac gcctgttata cgttcttggc tactttgttt cctataaaac agtttttcct
    10501 gttttctgtg tttcgccaag accactccca gaggcatttc ggcaaccatt cattgatacc
    10561 ttgcaccacc cggtatctct cttgtaatga tcagctgctt acttttttct gttcatcgtg
    10621 tttagttcag tacttgattt aaatgtgcta atgatttttc acgaccaagc aattcgatcg
    10681 tttcaggcaa ttctggacca tgcatttgtc ctgatacagc tacacggatt ggcatgaaaa
    10741 gattttttcc ttttacgcca gtttcttttt gaacagcttt gatggcagct ttgacagttg
    10801 gagcatctac tacttccatt tgttctagct gtgctttgaa tgcgtggaga acagtaggaa
    10861 ctgtttcacc agcaagtact tcttttgctg cttcattcaa tacaggatgt tcattgaaaa
    10921 atagcgtaga cagatcaacg atttctgcag catagctcat ttgaggttga tacaggctaa
    10981 cgatcttctt cacccattcg attgtctttt catctgggtt ttctgctaca cgtccatcag
    11041 cgattagata aggcagacac atgtcagtaa atgcatctag atccattgct ttgatgtaat
    11101 ggttgtttac ccattgcagt tttttcgcat cgaaagctgc gggtgattta cttaggcgtt
    11161 ttggatcgaa cattttgatc aattcttggt gttcgaagat ttcgtcttcg cccacaggtg
    11221 accagcccaa taatgcaata aagttgaaca ttgcatctgg tagatagcct aattcgcgat
    11281 attgttcgat aaattgcaag attgattcgt cacgtttgct tagtttttta cctgtttcac
    11341 tgttgatgat caatgtcata tgtccgaagg ttggtggtgt ccagccaaat gcttcataga
    11401 tcatcagttg ttttggtgta ttggcaatat ggtcatctcc acgtaaaacg tgagtgattt
    11461 tcatcaaatg atcatcgacc gcaacagcaa aattataagt tggcatacca tcgcgttttt
    11521 gtatgacaaa gtcgccaccg atattatcgg attcgaacga aatagcgcct ttcaccatat
    11581 ctgtaaatgc gtattctgta ttgcgaggca cacggaaacg tacaacagat tctagacctt
    11641 gtgcttcttt ttctgcttgt tcttcaggtg tcaagttcgc acatgttcct gcgtaatgag
    11701 gcatttctcc tcttgcgcgt tgtgcttccc gttctgcttc taattcttct tctgtgcaat
    11761 agcatttgta tgctcgattg ctagcaagca gctgatcaat cagcggttga tagatttctt
    11821 tacgttcaga ttgacggtaa gggccgtatt ctccaggatt ttcaggagat tcatcccaat
    11881 tcattcccaa ccaagcaagg ttttccaact ggcttttttc gccatcttcg atattacgtt
    11941 tttggtcagt atcctcaata cgaataataa agtctccatc attgtggcgg gcaaacaaat
    12001 aattgaataa tgcagttctt gcatttccaa tatgcaggtg cccagttgga cttggtgcat
    12061 agcgtacgcg tactttcgtc attttcttcc tcttctttca aactagactt tgactaacag
    12121 caaaaattcc gtcagttacg gcttctcaaa tatcatttat ttaaagccac tcagcacaaa
    12181 ttttaccttt tctaaggtaa atagtaaagc caactggttg aatttcctta ccagttggct
    12241 gaatttcttt tttattttga ttgtttagtc tttttctctg tctctttttt attgtcgatt
    12301 cctcgtcctg catgtgcagg tttagcaaag atcatgcgtc cagcagctgt ttgaagggca
    12361 cttgttacaa cgacttcgat acgttcattc atgtaatgct gtccatcttc tacgacaacc
    12421 atcgtgccgt catcaaggta ggctactcct tgttggcgtt ctgtcccggc ttttactact
    12481 agaacattca tcgtttcacc agggatgacg actggtttta cggcatttgc caacgcattg
    12541 atattaagaa caggtacatt ttggaattca gagactttat tcaagttata gtcattggtt
    12601 acaatgacac catctaaaag cttagccaat ttgatcaatt tgctgtctac ttcactgata
    12661 tcttcaaagt ctccatcgta catttcgaca gatataccct cttctttttg caaggcattt
    12721 aggatatcta atccgcgacg accacgcaca cgtttcaaac tatcccctga gtccgcgatg
    12781 tattgtagtt cgtaaagaac aaaattaggg atcatcaagg ttccttctaa gaatccagtc
    12841 tttgtaatat cataaatccg accgtcaatg atcacgcttg tatccaagat tttatattta
    12901 tggaaatttt ctcctgattt tcgttctaac agttgactct caacttgact agctgtttct
    12961 tgctcgattt ttttgcttcg tgaaccaaaa actttcttcc attcttcgat tcgtgtcgtt
    13021 cccattctca atcccagata gcctaagatg atcatcagta aaatcggcaa tacactattg
    13081 acgaatggaa tttccatatt gtaaagaggg gtcgagatca caacacctaa agtcaatccg
    13141 atgatcgcac cgatcgcacc gaagagaaga taagtcaagc tgacctcact tagtttttgt
    13201 tctacttgtt tgataatagc tgagatatgt ttggccaaca gcaaagataa taaaaagaaa
    13261 ataagtgcgc ctaacaggct gttggtaaat gtattattca gccatccgtt tgactgttga
    13321 ccgattgcct gccaagctga gggtaaaaat gaaataccca agcttgcgcc gacaatgatc
    13381 atcagcaaag taatgacacg tttttgcatc gtttttcctc cgtttcgaca atcatttatt
    13441 agttagcgga acacacgctt caacgtttca gccaaagttg ctactccaac tatctcgatt
    13501 ccttttggcg cttcccagtt acctaagttg tttttaggta ggtatacttt tgtgaagccg
    13561 agtttttgga cttctttgac tcgttgttca atatgactga cacgtctgat ttctccagtc
    13621 agtccaattt caccgatgaa acattccgtt ggctgtgttc ctttttcttt atagcttgaa
    13681 gcaatactga cagcgatagc taaatcaatc gctggttcat ttaattttac cccacctgca
    13741 gcttttaagt aagcatcttg attctgaaga agcaacccag ctcttttttc cagcactgcc
    13801 atgatcagag atacccgatt gaaatcaaga cctgttgttg ttcgtttggc atttccgaac
    13861 atagtaggtg tgactaatgc ttggatctct accaaaattg gacgtgtccc ttccattgcc
    13921 acaacgatag cagagccagt tgcaccgtct aggcgttctt ctaagaaaat ctgtgaagga
    13981 ttagcgactt cttccaatcc atgctcatgc atttcaaaaa tcccaatctc attcgttgag
    14041 ccaaatcggt tttttactgc tcgcaaaatc cgaaaactat gatgttgttc accttcaaaa
    14101 tataacaccg tatccaccat atgttctaac attcttgggc cggcgatcga gccttctttg
    14161 gtaacatgac cgacgataaa aatggctatc ccatttgttt tagcgatttt gagtagttct
    14221 gcagtggttt ctcttacttg gctgacactt cctgccacac ttgtgatgtc tggctgcgtc
    14281 atcgtttgga tggaatcaat gataacataa tcaggggaga tatgttcgat ggcacgactg
    14341 atttcgttca tatctgtttc agcgtataga taaaattctg tgttgatact tccgaggcgt
    14401 tccgcgcgta attttatctg ctctgcgctt tcttcgccgg atacatataa gacttttccg
    14461 cctatggctg ctaattgctg agaaacttgt aacagcaaag tggatttccc gatacctgga
    14521 tcgccaccaa tcaagaccat agaccctggc accacacctc cgcctaacac acggttcagt
    14581 tcttctaatt ttgttttgat ccgaggttct tttttaggga cgacgtctgc gatttttgtt
    14641 ggttttgctt tttctcctgt caaacttgtc cgagttctgc ggtccgttgt atcttgttcg
    14701 atttcttcga ccatcgtatt ccattttccg caatttgggc agcgtcccaa gaacttaggc
    14761 gacacatacc cgcaattttg gcaaacaaat tgtacttttg atttttttgc cattgtaccg
    14821 cctcctttta tcctaatcat gagacattaa atcaagctta agtatcttta acgttttatt
    14881 tactggaaga accaaatccg ccttgacgtt gagcagtcgt ttgatcttga tctgctttta
    14941 aaaacggcaa aaagatccct tggccgatac gctcgccttt tttgatcact acatccttga
    15001 aaccaaagtt ggtgaattgg aacatgatat ggccttcatt tgcctcatta ttgtaataat
    15061 cactgtcaat cacacctact ccgtttgtca acactaaaaa ccgcttcaac ggattgcttg
    15121 aacggttagc aagctgcaaa aattcatctt ctcccatgta agctttgatt ccagtaggca
    15181 cgagggttgg tttcaattgt ttttcatttt ctgatacatc ttttttcaat ccatctgcga
    15241 ctgtttccaa cccctttttc cagcctgctt tccagatact tggaatcacg acctcttctg
    15301 ctgcttcaaa atcatagcca gcagcatgat gtgtagcgcg ctgcggtaga ttgatatttt
    15361 gatctttata tttagaaata acttcaaatc ctctttttct caccggtttt cct
//
LOCUS       DAYNVV010000063        14212 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.066, whole genome shotgun sequence.
ACCESSION   DAYNVV010000063 DAYNVV010000000
VERSION     DAYNVV010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14212
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.066"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(163..2160)
                     /gene="tkt"
                     /locus_tag="ACGXWR_002245"
     CDS             complement(163..2160)
                     /gene="tkt"
                     /locus_tag="ACGXWR_002245"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFK0803772.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2262..2513)
                     /locus_tag="ACGXWR_002246"
     CDS             complement(2262..2513)
                     /locus_tag="ACGXWR_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HFK0803773.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2660..3283
                     /gene="lexA"
                     /locus_tag="ACGXWR_002247"
     CDS             2660..3283
                     /gene="lexA"
                     /locus_tag="ACGXWR_002247"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HFK0803774.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3463..3681
                     /locus_tag="ACGXWR_002248"
     CDS             3463..3681
                     /locus_tag="ACGXWR_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803775.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3970..4482)
                     /locus_tag="ACGXWR_002249"
     CDS             complement(3970..4482)
                     /locus_tag="ACGXWR_002249"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HFK0803776.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4496..6793)
                     /gene="recJ"
                     /locus_tag="ACGXWR_002250"
     CDS             complement(4496..6793)
                     /gene="recJ"
                     /locus_tag="ACGXWR_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HFK0803777.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6935..7378)
                     /locus_tag="ACGXWR_002251"
     CDS             complement(6935..7378)
                     /locus_tag="ACGXWR_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA
                     domain-containing protein"
                     /protein_id="HFK0803778.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7379..8167)
                     /locus_tag="ACGXWR_002252"
     CDS             complement(7379..8167)
                     /locus_tag="ACGXWR_002252"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFK0803779.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8164..9105)
                     /gene="rnz"
                     /locus_tag="ACGXWR_002253"
     CDS             complement(8164..9105)
                     /gene="rnz"
                     /locus_tag="ACGXWR_002253"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HFK0803780.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9282..9869)
                     /locus_tag="ACGXWR_002254"
     CDS             complement(9282..9869)
                     /locus_tag="ACGXWR_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HFK0803781.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10090..11403)
                     /gene="obgE"
                     /locus_tag="ACGXWR_002255"
     CDS             complement(10090..11403)
                     /gene="obgE"
                     /locus_tag="ACGXWR_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HFK0803782.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11700..12710
                     /gene="gap"
                     /locus_tag="ACGXWR_002256"
     CDS             11700..12710
                     /gene="gap"
                     /locus_tag="ACGXWR_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFK0803783.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12795..13730)
                     /locus_tag="ACGXWR_002257"
     CDS             complement(12795..13730)
                     /locus_tag="ACGXWR_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFK0803784.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            13916..>14212
                     /locus_tag="ACGXWR_002258"
     CDS             13916..>14212
                     /locus_tag="ACGXWR_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0803785.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKER"
BASE COUNT         3969 a         3159 c         2510 g         4574 t
ORIGIN      
        1 tctcaagaaa cacaaactaa tccgaagaat tctttgtttt gtcatttaaa tgtaacatag
       61 ccgaaaacga aaagtaatat tgatttattc ttctaacaca taaagaacag ctgtctccaa
      121 cttgcagaca gctgttctta tcagtcaaac aattgcttgg atctatgata gttgattgta
      181 cgtattcacg acattttcta ctgtaaatcc aaattcttct aaaattttag tgccaggggc
      241 agatgcaccg aaatgatcga ttgtaatcgt tgcgccctct gttcctacgt agcgttccca
      301 tccaaatgat gcagcagctt cgatagccac acgtttcttc actgatttag gaagtacact
      361 ttctttatat tcagaagatt gtttttcaaa gaggtcaaag cttggcatag aaacaacaga
      421 aacatctttg cctttttcag ccaattcttt ttgagctttc acagccaaat caacttcaga
      481 acctgttgca atcaaaatac cttctggtgt ttctccttgt gatggagaaa gaacatacgc
      541 gccttttttc accatttcat ctgctacttc ttttgtagaa ggcaatactg gaaggttttg
      601 acgactcaat acaaggatag taggcgcatc tgttgtctcc atcgctactt tccaagcagc
      661 acgtgtttca tttccgtctg ccggacgaat cacttgaaca ccaggcatgc agcgaacaga
      721 tgctagttgt tcaatcggtt cgtgcgttgg tccgtcttct ccgacagcaa ccgagtcatg
      781 tgttaagacg taaacaacag gagtatgttg gattgctgct aaacgaactg ctggtcttag
      841 ataatcgaca aagacaaaga atgttccacc gtagatacga gttccgccat gaagttggat
      901 accattcata gccgaagcca ttgcaaattc gcggacaccg aaccagatgt tgcgtccttc
      961 ataatgttca ggagtgaaat ctttatctgc agccaccatt gtattattgg aacctgacaa
     1021 gtccgctgaa ccaccccaga agcttggtat agctttcgat aattcttgga tgacttcttt
     1081 acttgaaaca cggcttgctt gactgcttcc aacttcataa gttggcaatt ctgcatccca
     1141 gttttctggt agtttgccat caaaagcatc ttcaaattgt tgtgctaatt caggataagc
     1201 ttttttataa ttggcaaaca tttcattcca tgcatcttca gctttttgtc cttcttctat
     1261 catcgtttga tggaagcggg cagctacttc ttctggaaca gtgaaatctg gatactccca
     1321 accataaact tctttagcca tcttgatgcc atcttcacca agaggagcac catgaacagc
     1381 agatgttcct tctttaggag caccatagcc gatgactgtt tttacttcga tcaatgttgg
     1441 tttgtctgtt tcagcttttg cttcttcaat cgctttagag attgcttcta ggtcatttcc
     1501 gtctttcact aagatatgtt gccagccata tgcttcatag cgagcaccaa cgttttctgt
     1561 gaaagctttt gaagttggac cgtctagtga aatatcgttt gaatcgtata aaacgatcaa
     1621 tttccctagt ttcatatgac ctgccatcga acttgcttct tgagataccc cttccatcaa
     1681 gtctccgtca ccgcatattg catacgtata gtgatccatc acattaaagt tttctttgtt
     1741 atacgttgct gcaaggtgcg cttctgccat tgccataccg acagccattg caatcccttg
     1801 tcctaatggc cctgtagtgg cttctacacc atctgtatga tgtacttcag gatgtcctgg
     1861 tgttttagaa tcccattgac ggaattgttt caaatcatcg attgtcactt gatagccagc
     1921 taaatgaagc aagctataca acattgctga cccatgtcct gccgaaagaa cgaaacggtc
     1981 gcggtcagcc cagttttttg atgtcgttgg atttactttc aggtgttttg tccataacgc
     2041 atatgccata ggtgctgcgc ccatcggcaa tccaggatgt cctgagtttg ctttttggac
     2101 tgcttcaata cttaatgtac gaattgtgtt aacgccaagt tggtcaattt tgtcaaacaa
     2161 aataacccct cctattaatt taggtttttt ttacctttat ttcttacact ttcattctat
     2221 aagatgtcac acgaaaaagc aatctttttc agtatttttt actaaaagtt gtcatttcgg
     2281 ttgtgtaagc cttttttctt ttggatttct tttaattttt ccggggtcac gtcattgccc
     2341 tcaggatcga cgactttcat tccttcgata tgatgacgca taccggaacg aaaagcttcc
     2401 aaatactctt tgcgcaagtt gatttgttct tgttcttcgg cttttgagag accattttcc
     2461 ttctttttac gtgcaagttc attgatccgc tctatttttt caggtgacag catgctcagc
     2521 cctcctttta ctctccttca tattatataa aaactgaaaa aaaaacaact agataaacta
     2581 aataaaatac gaacattcgt ttgatttagc gctttttata tggtactatt tatttatcaa
     2641 gtgaaagaag gtgtaccttg tggcccgaca aactgaatca agacaaatcg aagtcttacg
     2701 atatatccat gaacaagtaa cccaaaaagg atacccgccg actgtccgtg aaatcgggga
     2761 agctgttcag ctttcttcta cttctactgt tcacggtcat cttgcacggc ttgaaaaaaa
     2821 agggtttatc caaagagatc cgacgaaacc tcgtgcaatc gagttgacaa aacaaggttt
     2881 agaaaagatt gggattcgtc caacaactat tccagtactt ggcgtcgtaa cagctggaga
     2941 acccatttta gcagtagagg atgcttcaga cttctttcca atccctccta atctttcttc
     3001 cgaagaaggc agtctcttta tgctgacaat tcgtggagat agtatgatca atgctgggat
     3061 attggatggt gacaacgtga tcgttcggaa gcaagaaact gctcaaaatg gcgatattgt
     3121 cattgcaatg actgccgagg acgaagcgac ttgcaaacga ttctataaag aaaaaaactt
     3181 tttccgtctg cagcctgaaa acgacttgct cgaaccaatc atcttagatc aagtatctat
     3241 attaggacga gtagtaggac tttatcgtag tcatatctat taattgctac taattaaaag
     3301 aaaacttttt aaaaagagtt tgagacgttg gtctcaaact cttttttcgc ccgggttctt
     3361 cttctttcaa atttttatca cttccctctt tacaaaccga acaaatattc gtatactaaa
     3421 tatacgaaca attgttcgca taaattaaag aggtgagaat tcatgaaatc aatgagacgt
     3481 cttggcttag tattaactgt tttgttttta ggtattatta ttggtaattt cggcatacgt
     3541 ccagctttac ttgtgtttgt tccgttattt actttgtggt tcatgttgtg ggatgaaaag
     3601 aagtaccgtc aatctgagcg gcgcagaatt catgaagatc atttctatca tgagccctac
     3661 tacagatcca ggcaatcata ataaggattg actgctaatt attcaaaaga caagaagtta
     3721 aacttttacg ggggtgtgac aaaaatcggt cacatccttt ttttcgaata aacggtgttc
     3781 taaagccagt ttttcggtat taagtcaaat tgcggaaaaa gtgatttttt aaacttctac
     3841 tggtctttgc ttgtttccat ttataaaaaa atagcgaccc tcaaaagtca gatagagaat
     3901 ctgacttttg agggtcgctt taaaatcgct tctttaagaa taacatcaag aatagcttct
     3961 tttttctgct taatattcca ttaatgtaat gatgtcatat cctttgattt tgtcgcgtcc
     4021 atggagatcc atcaattcga tcaaaaatgc gcagcctacg actacaccgc ctaattgttc
     4081 gatcagttcg atcgtcgctt tgattgttcc tccagtagct agcaaatcgt cacaaatcag
     4141 cacacgttga cctggtttaa tggcatcctt atgcaatgtc aatgtatctg ttccatattc
     4201 taatccataa gtcacttcga tggtttctcg aggtaacttc ccttttttgc ggactggggc
     4261 aaaaccgact cctaactcat aagcaacagg acatcctacg atgaatccac gggcttctgg
     4321 cccaactacc atatcaattc gtttttcttt tgcataattt acgatttgtt tagtagcttc
     4381 ccgataagcg tcaccatctg ccatcagtgg ggaaatatct cgaaacacaa ttccttttga
     4441 cggatagtcg ggaatactgg caatataatc ttttaaatcc actctttgtt tcctcctagg
     4501 ttgttaacca tttctttatg gtaggaatat cgctcaaaag caaaaattcc tcaactttga
     4561 ttttattgag ccgtcgctgg tataatctgc tctcagtcaa aggatgactt tctgggctag
     4621 cgactttttg taaaacaccg ttctctattg taacaaattt caattcaaaa aacacctgta
     4681 tcataaaaat taataatttt tcagggatac gcaaatattg agctattgct tttattttat
     4741 gacgtatatc aattcgttct tgagaatgga tcaatttaaa caattttgcg tactgttctc
     4801 ttgtgcctac cccattcaaa taggcctcat caggtgaaat ccccatcaga taaacacgat
     4861 tgaatgaata agaccgaaaa acttctttca gatccgctaa atcatctgga caatccataa
     4921 caactagaga gtttggtttt cttttttcaa ttattgcctt tacagaatct agtccttcga
     4981 aaacaatcgc agcttcctgg ataatctcag gcacgaattt caacgtcgaa gaatcaaatg
     5041 ctaaataaag gctaccttcc gacgttcggc tctgttcacg gaaacgtttt gcccgccaat
     5101 caaatacttg cagaccaccc acagaaaaat cagataccat cagctgcggt ttcttacgcc
     5161 cgttccattc attgatcgaa agctttccta ccacatctac ctgattattc agcagttctt
     5221 cttcttgagt accaaaacca aaagcgaccg catcaagctg actcgatgca tcggaaagga
     5281 caaatttcag atgctgttgg tttgctccga ttcttttgat attttctgct tggacttgtc
     5341 gaaataaaaa ctgaggcaaa ggattatccg taccaaatgg cgccaatagt ttcagctcat
     5401 caattcgctc tactgttact tcatttggca gcaatacttc atcaattctc aactcaggcc
     5461 ctctcatcaa gtcaatttga tgatcgacta tatattggtt catcttctcc tgtagtatag
     5521 tgacattttc acttggcatc gttaaaccga ctgctgcatg atgtcctccg aagtaagtaa
     5581 ataaatctcg catctggtca agcatttcaa aaagattcaa ggcttcaata ctacgtccag
     5641 atcctttagc tgatccatct tcttttaaag taaggacaag agttggttta cccgtttcat
     5701 tcattatttt cccagcaaca atgcccaaaa cgccttcatg ccatcctcgg tttaccaata
     5761 gatggatatg attctcctta ttgaccatcg ctaatgcttc ttgtgttatc tgctctacga
     5821 ttgcttttct ttcttcattg atctcattca atttttttgc ttgaacggat gcttcctctt
     5881 catcaaacgt cgcaagtaac gagacggcag gacgtggatc gcccatccga ccgattgcat
     5941 ttagtctggg agcaatcgaa aaaccgatcg ttgtttcgtc tgcgtccctc atttttacgc
     6001 cgctttcttc aaatagcgcc tgaagtccta tccgttctga atgatgaatg gcatcgattc
     6061 ctaatgaaac aaggattcga ttctcatcag tcaatgaaac taaatcggcg atcgttccta
     6121 tcgctactaa atccaaaaat tctgcaggcg gttcttccaa taatgcagaa gctactttga
     6181 atgctactcc gactcctgcc aaatctggaa atggatagtg ccccgctgga tgacgagggt
     6241 gaacaatcgc ataagcgtct ggtaaattct caggtagttc gtgatgatct gtaatgatca
     6301 cgtctacacc agcttgctga gcgtatgcta ccgcatcatt tcctgctacc ccgttatcaa
     6361 cagtgatgat caactggatt ccttcttcga tcttttcttg gtataccgat tggtttggtc
     6421 catacccatg ctcaaatcga tttggcagga atacttctac ttctgcacca agtaattcca
     6481 gtgtttcttt cattaccgtt gcactggtga tcccatctgc gtcataatca ccgtaaacga
     6541 ggattttttc tccactgatt acagcttctt ggattcggct gattgcttta tccatatcgt
     6601 gtatcagata cggatcatgt aattcttgtt cctttggatg taaaaatcgg ttgatatcct
     6661 tttcctcatg gtaacctctt tgccacagta acttaccgac aaatggagat aatttcagtt
     6721 cacggatcat ttggagaaag gattcagaag gctctgtctc gcttaacttc caatcaaaat
     6781 ttgcttgtct cactttctca ctcctaactt agttattata gcaaaggaaa tcagcaaaaa
     6841 aaagcagaaa gaaagaataa aaacagatca gatccgctag acagatgttc agcaggacct
     6901 gatcttttgt acgaccattt atgaaatatc cctattagtc aaaataattg aagctttgtt
     6961 tgggcgattg agttttttgt tcttccggcg ctttcaattg actgatttgt gcggttttcg
     7021 cttgtaactc cgcctgataa gcagcttcca actccgcacg ttcgtttcta aactcgcgtt
     7081 gctgttcttc ttttgcttct tcaattttct tttgaagttc tgtttgatat tctgacattt
     7141 cctgagtcag ctgtttgatt tgcttttttt gctgccatag tgttgccgaa gcagtcaaaa
     7201 atacaatcag tgcaccaatc agcgcagaac cgatgatcac taagatcaat ggcgcagaaa
     7261 aggaagtgaa gccaaaactt acaggaacat ttttattgtt caatacagca aaaagaacaa
     7321 taatcaaaac taaaacaaat ccaagaatca cattgctttg ctttttcaat tccttcacct
     7381 actttttgtt aaaaattccg ctggctaaat aatcaccaat cgttggaaac agcgtataaa
     7441 attttgatgc aacttctaaa ataaacggtt gattgatttc ccgttttgga tgtctcatat
     7501 tgcggacgat catttttgcc aacttggcag gttctaaaac gatttgtccg actttttcca
     7561 aatagcttcc gcttggatca gccttatcga agaaatttgt ctcgattgga cctggattca
     7621 ctgtcgtaac agctacgcca agtggtttca attctaatcg caaagcgttg gagaagccaa
     7681 ggactgcaaa tttcgtggca gaataaaccg ttgattttgc agttgccatt tttccagcca
     7741 tagaggcgat attaatgata tgaccttgtc ttctttctgc catatcgatc gcaaattttt
     7801 gtgtcaaaac catcattcct aagatgttga cttcaaacat atcgtatgct tttccaaggt
     7861 cgaatgtaag gaagtcttcg aaaatcccaa aacccgcatt gtttaccaga atatcgacgc
     7921 gcccgacttc ttccatcacc ttttcatata attcgtccac gctttcagga ttgctgacgt
     7981 ctaccttgaa agcataagcc tctttgccgc tcaagcgtct gcactcgtct ctgacacctt
     8041 ctacaaatgc cattcttcgt gcgcaactta taacgattgc tccttgcttt gctgcttcat
     8101 aacagatttg tgcgcccaga ccgcctgaac tacctgttac taaaacaact ttatcttcta
     8161 aattcatgcc tcttcctcct cgcgaaatgg aatctcaatg ctatcaaaat ctttcataat
     8221 cgtcgtgttt tcaaacactt cttgtgcttc tttttcaagc tctaaagctg cttttcctaa
     8281 atatctcgca ctgatatgag taagtagcag ccgttttgcc tgcgcttctt ttgcaacttc
     8341 agcagcttga tgagtcgtgg aatggaaata gttgtgcgcc attcttgctt catctttatt
     8401 aaatgtgctt tcatgtacca gaatatcgct attttccgca agcacaacgg aattatgtgt
     8461 ttttctcgta tcgcctaaaa tagtcacgat tcgtcctttt ttatctggac ctacgaaatc
     8521 ttttccattg atcgtccgcc catcttctag ttggatcgtt tcaccttgct tcagtttgcc
     8581 gtacagtggt ccagctggaa tacctaattc ttttagacga tccacctgca attctccttt
     8641 atgatcatgt tcaaccacac gataaccaaa actgtcgatc ccatgattta gtttttttgt
     8701 ataaacagaa aattgctgat cagtaaaaat cggggctgtt tcatttagct caatgaattt
     8761 cagcggataa cttaaacgcg tttgcgaaat acctaaagag acttttatgt attcctctat
     8821 cccttttggc ccgtaaatct ctaatggcgt atccccacct tgaaatgacc ggctgctgat
     8881 gagcccggga agtccaaaaa tatgatcgcc gtgtaaatgt gtaatgaaaa ttttaccgat
     8941 ttttctcgga cgaatagtcg ttcgcaaaat ctgcatttgc gtgccttcgc cacagtcgaa
     9001 caaccaaact tcattgcgct cgtctaaaag tttcaatgct atacttgtca catttctatg
     9061 ttttgcagga acacctgcac ctgttcctaa aaattgtaat tccataatct acctgacttt
     9121 ctttaagttc ctctttaatt ttagggtaaa aagaagggat aatcaaccgt aagtcgagaa
     9181 tgggttcaaa ttaaaaataa cgttctaaag cgatagcgtt ttctttgaaa attactataa
     9241 aaacagcagc gaacccgttt gagatcctct gctgtttttt attaatttga agatccagaa
     9301 ctttcattgt cgttggaagt ttgcggatgt ttgtccttcc aagtcttttg tgcagcttct
     9361 ttcgcatgat tttcagcttc tttcgcatca tgcacatctt tttcgacatc ttcataatcc
     9421 aagcgagtaa tttctccgcc taattccatc attaccaatt gattcagtgg gcgattgtcc
     9481 tcttcatcag caatcaagat cagtcctgta gctccttcac cgattttatt tcctacaaag
     9541 tcgaacacgg tctgggcatc ttttatttct ttggcatctt gtgtcgcacc gatcattcct
     9601 ccggcaaacc atcctaataa aatccctagc ggaccaccta atacaccaac caacattccg
     9661 attaatccac ccgtagaaga tttgttatta ccggtaaagt cgataaaatc ttctattttg
     9721 aattgatgtg tcccattagg atcatggctg acaactgcca tctgttctcc tttaatcgaa
     9781 cgaacagcat gtaacttttt gatttctgaa aatgcctgat atgcctggct ttctacttga
     9841 aaatttaaaa tgattactcg tttgctcatt aaaaacgccc ctttcatacc ttcttgttat
     9901 ttattttacc tttaattgta aaataagaaa agaaaagcac tctttttttc caataaaata
     9961 gggctgtgac aaaagtcgta tcacagctcc tttttccgaa taaacggcgt tcttgaagct
    10021 gatcacttct gtcacaacct cccttaaatc tgaatctata ttttttggta tttgttttta
    10081 tttgcttgcc tattcgacaa attcaaattc aaactcaccg atacgtacaa ggtcgccatc
    10141 tttcgcaccg cgtgcccgaa gagcttcatc cacacccata ccacgtaatt gacgagcaaa
    10201 acgcatcact gtttcatcat gatcgaaatt cgtcatttgg aataattttt cgatcttctc
    10261 accagataag atccacgttg catctgaatc acgatcgatt tggaactcag gaccttctgg
    10321 attgaatcca tagtgtacag tttcttcttc cagttcttct tcgtacaatg ggaattctgg
    10381 cgttacttct aacaaatctg ctgtagcatt caataacgcg tccaatcctt gtcgagtcac
    10441 tccagaaatt ggaaatactg ggatgtcatc agcaaattca tcttcttttt ccttgttcag
    10501 ctgttctttg aatttcacta gattttccgg tgcatccggc atatccattt tgtttgccac
    10561 gatgatttgc ggacgctcta gcaagcgtaa gttataagta gataattctt tgttgatggc
    10621 aagatagtct tcataaggat ctcgtccttc catcccactc atatcgatca catgtaaaat
    10681 tactcgtgtt ctttcgatat gacgaaggaa ttgtgtaccc agcccaacac cttgcgaagc
    10741 tccttcaatc aagcctggca agtctgctgc ggcaaaactt ctgccatcac ttgtagtaac
    10801 cattcctaga ttaggtacga gcgtcgtgaa atgataagcg ccgatttttg gacgagcaga
    10861 tgaaataacg gatagtaaag tcgatttccc gacagatgga aaacctacaa gtccaacgtc
    10921 tgccaatact ttcaattcta gttcgatttt tcgctcttgt cctggttcac cgttttcagc
    10981 aatttccggt gcaggattcc gaggagaggc aaaacggata ttccctcgtc caccgcgtcc
    11041 accttttgcc acaactagtg tttgaccatt ttcaattaaa tctcctaaaa gagcaccagt
    11101 ctccgcatct cggacagtgg ttccttgtgg tactttaaca taggtatctt ctgaaccacg
    11161 accgtgcatc cctttactca tcccattttc acctggctgc gctttgaaat ggcgattgaa
    11221 ccgaaaatcc atcaatgtac gtaacccttc atcgacgatc aagatgacat cgccgccacg
    11281 accaccgtct ccgccagccg gtccgccgtc aggaacgtat ttttcgcgac gaaatgcaac
    11341 cattccgtct ccgcccttgc cagctttcac atcgatcgtt acttgatcta aaaacatgga
    11401 cataattaag tcctcctatt attcatttat ttatttgact gcctgaattt ccacaataaa
    11461 caaaagtctt acttatttta tcggtgaaat ctgattttgt ctatcatttc agcaaaaaga
    11521 ttgtttacct tcttcttttt ttatcatttg gtaaggtttc caaccttttt tctgctacca
    11581 agtataattt tttgacaaaa tattctttgc gtagcagaat aacagtgtat taattgtatt
    11641 aattgtatta attgaggatg ccgtttcaca gcacccctaa taaaggagga acttttgata
    11701 tgacagtaaa agtaggtatt aacggatttg ggcgtattgg ccgtctggct ttccgccgca
    11761 tcaaagaagt ctcagatgat attgaagtag tagcaatcaa cgacttaaca agtccaacta
    11821 tgttagcaca attattgcaa tttgactcta ctcatggtac ttatcctggc acagttactg
    11881 caacagaaga ctcaatcgta gtggatggcg aagcaactcg tgtttatgca gaacccgacg
    11941 caagcaaaat cccttgggca aaagaaaacg gtgtagatat cgtactagaa tgtactggtt
    12001 tttatacatc tgaagaaaaa gcaaaagcgc atttagatgc tggtgtcaaa cgagtagtta
    12061 tttctgcccc agctggtgct atgaaaacca tcgtctataa cgtcaatgat gatacattag
    12121 atgaaaacga caaaatcatc tcagcaggtt catgtacaac aaactgttta gcacctatgg
    12181 cttatttctt aaataatgaa tttgggatcg aagttggtac aatgacaaca gttcatgcct
    12241 acacttccac acaaatgctc ttagatggac ctgtaaaagg cggtaatttg cgtgctgctc
    12301 gttcagctgc tgacaatact atcccacatt ctactggtgc tgcgaaagca atcggcttag
    12361 ttatccctga gctacaagga aaattacaag gacacgcaca acgtgttcca gtcgttgatg
    12421 gttcattaac tgaattggtt tcagtattga aaacaaaagt aactgctgat caagtaaacg
    12481 aagcaatcaa aaaacacaca gttgacaatc cttcattcgg gtatgatgac cgtcaaatcg
    12541 tttctagcga tgtcattgga acaactcaag gttcgatctt tgacccaacg caaacagaag
    12601 taacaactgc tggtgatttc caacttgtta aaactgttgc atggtatgac aatgagtatg
    12661 gatttacttg ccaaatgatt cgcttactag aaaaattcgc taacttgtaa tttgatagat
    12721 caatcgataa aagaagcctt tgactggatc cagtcaaagg cttctttctt ttcatcccct
    12781 acttttaaac tcgttcaatg aacatattgg cttaaaaatt gttggactac ttgctgatat
    12841 ttttcaggat ctgtcttgta tgcttccgca tgctcggctc cttttacaac atacttttct
    12901 tttggtccct tcgttgcacg atagacctta tctaacattt caaatggtac aaatgtatct
    12961 tcgtctccat gtataaagag cattgggcgc tggtttttct tcaattgttc cactgcattt
    13021 gcttcaccga aaaagtagcc agcacggact tttgtcacta gactcgttac ttgcataagc
    13081 ggaaatgctg gaagactaaa catatcgtct agctgataag caagctcatc atgaacggaa
    13141 gaataaccgc aatcttcaat gattgctttc acattatctg gtagtttttc tccgctagtc
    13201 atcataactg ttgctgctcc catgctgaca ccgtatagaa cgatttcttg cgattttcca
    13261 ttgttttcta gcactttgtt tatccactgt acatagtctt tacgctctgg ccatccaaat
    13321 ccaatgtaat ccccttcgct ttttccatgt cctcttgcat caggaacaag gacattgtaa
    13381 cccatatcat gaaacatctt tgcgtaattg gtcatcgttt cagcgtttcc catatagcca
    13441 tgagccacaa gagctgtttt ttcacttttc gtttcagcag gaagataaat cgctgataat
    13501 ttcagaccgt cttttgaagt gatggtccaa tcgcttcggt tttcttttga actaaaccat
    13561 ttatgtgcat ccgtttcttt ggatgtctgt gttgtaccag gtgtatcttc gtctaaaaag
    13621 tctttctcag aaggcacaac agcataatta taaaaataat tccctgcaaa cactaacgca
    13681 acaatcagag ctaaagcgac gcctaaaagg attttcatcc aaagtttcat aaatcatcca
    13741 tctcatttct cttttttcat ataaccttga attagtataa tcaaagaatc tctactatgc
    13801 aatgttcatt tttataaccc gcgaattgta aaattaagtt agaaaaataa aaaggcattt
    13861 atggtacact caaattgtat ttccgacgaa agaaaacaaa ggagtgtaac cataaatgac
    13921 ctacaaacat cttaccatag acgaactgac aatgatagaa tcatattatc ttcaacataa
    13981 taagccggtt gaaatcgcta accgaatggg acgtgctata caaactattt ataatgtagt
    14041 caataagttc aagcaaggca agactgctct tgattattgg caccagtata aagaaaataa
    14101 gaaaaaatgt ggtagaaaag tcattcaatt acctgctcat gaagtagatt acattaaaga
    14161 gaaagtcact cttggttgga cgcctgacgt cattatcggg cgaaaagaaa gg
//
LOCUS       DAYNVV010000064        14118 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.067, whole genome shotgun sequence.
ACCESSION   DAYNVV010000064 DAYNVV010000000
VERSION     DAYNVV010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14118
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.067"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..556)
                     /locus_tag="ACGXWR_002259"
     CDS             complement(<1..556)
                     /locus_tag="ACGXWR_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HFK0803786.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGA"
     gene            complement(572..1051)
                     /locus_tag="ACGXWR_002260"
     CDS             complement(572..1051)
                     /locus_tag="ACGXWR_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HFK0803787.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKARLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(1057..2081)
                     /locus_tag="ACGXWR_002261"
                     /pseudo
     CDS             complement(1057..2081)
                     /locus_tag="ACGXWR_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
     gene            complement(2098..3204)
                     /locus_tag="ACGXWR_002262"
     CDS             complement(2098..3204)
                     /locus_tag="ACGXWR_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFK0803788.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(3433..6030)
                     /gene="adhE"
                     /locus_tag="ACGXWR_002263"
                     /gene_synonym="adhC"
     CDS             complement(3433..6030)
                     /gene="adhE"
                     /locus_tag="ACGXWR_002263"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HFK0803789.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(6335..6715)
                     /gene="yajC"
                     /locus_tag="ACGXWR_002264"
     CDS             complement(6335..6715)
                     /gene="yajC"
                     /locus_tag="ACGXWR_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFK0803790.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(6812..7957)
                     /gene="tgt"
                     /locus_tag="ACGXWR_002265"
     CDS             complement(6812..7957)
                     /gene="tgt"
                     /locus_tag="ACGXWR_002265"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HFK0803791.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            8175..8873
                     /locus_tag="ACGXWR_002266"
     CDS             8175..8873
                     /locus_tag="ACGXWR_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFK0803792.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(9041..11680)
                     /locus_tag="ACGXWR_002267"
     CDS             complement(9041..11680)
                     /locus_tag="ACGXWR_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFK0803793.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(12299..13330)
                     /gene="queA"
                     /locus_tag="ACGXWR_002268"
     CDS             complement(12299..13330)
                     /gene="queA"
                     /locus_tag="ACGXWR_002268"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HFK0803794.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            13523..>14118
                     /locus_tag="ACGXWR_002269"
     CDS             13523..>14118
                     /locus_tag="ACGXWR_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0803795.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEA"
BASE COUNT         3959 a         3096 c         2543 g         4520 t
ORIGIN      
        1 aagcgcctac gagataacct cccataaaca aagcagagat cgaagcacca ccagcaacaa
       61 gtgaatacat gataaaagca gtacttggag gaatgaccat acctgtcgga gctgacgcga
      121 tattgaccgc tgtcgcaaac ttccggtcat atccttcttc cacttgctga gggatcaaca
      181 ctccaccaat cgcggtagaa gcggcaatgg ccgagctaga gatggaacca aataaagcat
      241 tccctaacac attcgtatga gccaaagccc ccggcacgcg cccgacgaac aacatcgcaa
      301 aatccactag tttcttagct atccctccat tattcatgat aatgcccgag agaacgaaaa
      361 acggaatagc gatcagcgaa aaactattga tacttcccac cattttttga gctgaactaa
      421 aagcagaaac atcaaacggt ataactaaca ataaagtcat catcgatgag aatgcaatac
      481 ttatagcaat cggcatccct aatacaagca acacaacaaa tacaaaaaat aacactaatc
      541 cggcttctat tgccatttta ttcctccatt tttatatttt ttcttgaatt gctggcttgt
      601 tgcttaatgt atcgattaga ttgatcaggc tatagataat gatgagtacc cccgatacag
      661 gtactgacag ataaacatat cccataggaa tacttaaaga aggcgagatc tgccccattg
      721 tcaatgtgac agcattccat ccgccataca ccatgatcat cgcagcaaat accagaaata
      781 aactttgaac aacaacttct aaaattttac tttttttgcc agttaatttt tcacttaaaa
      841 ccgttacggc taaacgtgct ttttgtccca caacatacgc ggaagacaac atggcaaacc
      901 agacaagacc gaatcgaaca agctcttccg tgaccgtatt tggatttcct aaaaccgttc
      961 tggaaaatac ttgccataaa acaacagcga ccatcccaac aagcaaaaca gctcccagga
     1021 tctctaatac cttgtttaaa atcattttca ttacagctac gctccttgct cttggatctt
     1081 ttgataaagg tctttgtagg taggatcgtt tttgaatata tcatgaagtg gggcaactgc
     1141 ctctcgaaac ggtgtattat ctacatcatt gaattggact ccatgttctt cttgtgctaa
     1201 agctttttct tcttcaattg cttttgcaaa agcttcaatt tcaaaaaccg ttgattcttt
     1261 cgctgcttct tcaatggctt tttcctgttc atcagttagc tgttctttga tggcatcatt
     1321 catgatgatg atatctggca cacgtgtatg ctcatcatag gaatagtatt tagctacccc
     1381 gccatgtcca gctgtataca agacaaattc attgttttct gatccgttga tcaaattgga
     1441 ttgaagagac gtgtacactt catcacttcc cataggtacg ggcgaaccgc ctaaaagctc
     1501 taccattttg atagcggttt cgctttgcat cacacggatc ttctttccct tcaaatcttc
     1561 cggcgtatgg atcggaccgt ctaccatata aaagctgcgc tgaccagaat cataataggt
     1621 caatccggta aatcctaaat ttttggtcga ttggtagatt ggctccatta tttcttcatt
     1681 atccatcacc ttaaagaaat gttcttcatc attgaataga taaggaacgg aaaaaatcga
     1741 ataatcttta gagaaacttt ccaacgctga ggcacttact tttgtgaaat ctactgctcc
     1801 tgactgtgtc aattcgatca gttcacgttc tccacccagt tgtccatctg ggaaatactg
     1861 gatctgtacg gaaccatctg ttttttcttt tactaaacgc ccaaattcat tcattgcatc
     1921 aattactggc tgttgcttgc ataagcaaag cgcaaggtaa ctatctcatt tacgtctgca
     1981 tctgcgacag ttgccacact agaattattt ccgcagccgc ttagacctag cagacctagg
     2041 ctaagcgaac ttgctgcaaa cagcagtgat gtttttttca tatgggtttc ctttctttta
     2101 acaataagag acgagcaatt ctgtcaaaca aagcaccgtt aacgactgtc cataaggcat
     2161 tgctgtgatt ccgatattcc gataaaaatc taaactgtcc cccattcctg tcccgattga
     2221 aacgttttga acttctcctt tttcatcgat ttgttcaagc aatccttgga tagcacgata
     2281 agcgacttct ttatattctt gtggtaaata acgtttatgg accgctttca aaataccgta
     2341 agcaaatcct gcagttgcag aagattctac gtaagaagaa ggatcatcca acaacgtatg
     2401 ccataaaccg ctttcagact gataagtttt taatgcacgc acttgtgctt caagtgtttc
     2461 gatcaataat ttgcgcaatg catcttcttt cgataattct aagatttcaa tgatctctgg
     2521 aatagcaatc gtcaaccagc agtttccacg agcccaaaat gcttcggcat agttatgatt
     2581 tccttcaaac gtccagccgt gataccacaa tcctgttcgt ttatccatca agtatttgat
     2641 atggatcata aactggtaac gagcttcttc taaatattct gggcgattca acagtttccc
     2701 gatttttgcc aaaggaagca ctgtcatcat caatgtatcg tcccacaact gattcttatt
     2761 ttccggtcca tatgtggcat gctgtaaccc gtcttcattt gtccgaggca tgtcattcat
     2821 gacccattct gcccattgtt ctaaataagg caaatagcgt gaatctttcg tgtcttcata
     2881 caagtaagcc atagtcaata gcggtgccat tgtattgacg tttttgggcg gagcgccttc
     2941 ttccatacga tcctcaaacc attcattgac cacttgataa gcgcgaggat tttttgtcat
     3001 ctggtaattt ttataaatac catatagacc gacaccttgt ggccaattcc acactgtcca
     3061 gcttttgtca tctactttca gtccatcaaa gtccaacaaa aattcaccat tatcgtcttt
     3121 gatcgttgtc aggttttcaa cgagcaggtc aattttttct ttcactaatt ctttaggtac
     3181 aaaaatctct tctttaataa tcatctttac gccacctttt taaacgcttt cattttatat
     3241 ccttaatata gcagtaatac cgtccactat aaatatcgct ttttgaacaa aaactgtcta
     3301 aaattgacct aaatgttaaa taacaaaagt aactttcagt tacttggaaa ttaaaaaaag
     3361 aacttggaga aacaacgttt tccaagttct ttttcatcta ttttcttatc ttttttctac
     3421 gctttctttt gcttatccgt tgtaagcatc aatgatgatc tgtttcaatt cagagatcaa
     3481 tggttctttc ggattagctg tcgtacattg gtcttcgtaa gctaattcag ccatacggtc
     3541 tacggttgta tctagtgttt cttgtgtgac tccttgagct tttagactca tgttgatgcc
     3601 gacagatttt cctaattcat aaacagccgt tgctaaagct tcgactaatt cctctgttgt
     3661 ttcgcctttc agacctaaga attttgcgat atctgcgtaa tctgtatctg cacggaaata
     3721 gtcatattta gggaacatcg catgtttttg tggatctttt gcattatagc ggataatatg
     3781 cggtaaaaga atcgcatttg tccgtccatg agggatcccg tattccccgc cgattttatg
     3841 tgcgactgag tgacaaatac ctaggaatgc gttagcaaac gccataccag ccattgtaga
     3901 agcgttgtgc attttttcac gtgattccat atcaggtgtt tttactgatt tttctaaata
     3961 gtcaaagact aacttgattg cttgtaggct caatccacgt gtataatctg aagccatgac
     4021 tgaaacatag gattcgattg catgtgttaa cacatccatc ccggtatctg ctgtgacaga
     4081 tgctggaact gacatgacga attgaggatc gacgattgcg acatctggcg tcaatgcata
     4141 atctgctaac ggatatttca catgtgtttc actgtcagtg atgaccgcaa atggcgttac
     4201 ttcagaacca gtccctgatg ttgtcgggat acatacgaat tgtgtttttt ctggtttgtc
     4261 gatcttatat gtccgtttac ggatatccaa gaatttttgt tttgcaccaa agaaagatgt
     4321 gtctgggtgt tcatagaaca tccacattcc cttagctgcg tccattgcag aaccgcctcc
     4381 aagagcgatt actgtatctg gcttgaagtc tgccatcagt ttcgttcctg cgtatacggt
     4441 atttgtcgat gggttcggtt caacatctga gaagacttcg atcttcacat catttttacg
     4501 tcgtgccaat acttcacgaa ctgtatcgca gtaaccgaat tggaccatac cagggtcaca
     4561 aacgatcatg acacgttcaa cgttttccat tttctctaag tacaatagag agttcttttc
     4621 aaagaagatt tttggcggta atttgaacca ttgcatgtta tttctccgtt tcgctacagt
     4681 tttgacattg attaagttta cagcagagac gttacgagaa acagagttct taccataaga
     4741 accgcatccc aaagtcaatg acggaatcat ttcgttatag atatcaccga tgccgccttc
     4801 tgcagatggt gtattcacta aaatacgaca agctttcatt cgaagaccga atttgacatg
     4861 caactcttcg ttttctgaat ggataactgc tgtatgtcct aatcctccaa gattcaacat
     4921 accttcacac aaatcaaacg catggtccgt gttgttagct ttgatcatgg caagaactgg
     4981 agaaagtttt tctcttgata gcggataatc tgggcctacg ccttccaatt cagcaatcag
     5041 cattttcgtt ccttttggta cactgattcc tgccaatttt gcgatttcca tcgcagaatg
     5101 tccaacgatt gatggattga ccgcatattt tccttcgttc atcactgcat cttctaattt
     5161 ttgcaattca tctggtttta cgatataaac ttggtgtgct tggaattctg cttttactgc
     5221 tgcatagatt tctttatcca cgatcacagc ttgttcagaa gcacaaatca ttccattatc
     5281 aaatgttttc gaaacgatca aatcgttcac tgcacgttta atttttgctg ttttttcaat
     5341 ataagctggt acgttacctg gacctacacc taaagctggt tttcctgtag agtaagcaga
     5401 cttgaccatt ccagctccac ctgtcgctaa gacgatcgcg atacctggat ggttcattag
     5461 catagaagtc gcttcgatcg aaggatgttc gatccattgg atacaatttt caggagctcc
     5521 ggcagcgata gcagcatcac gtaccactcg tgctgcttct gcagaagatt tttgggcact
     5581 tggatggaaa gcaaaaacga ttggatttct tgttttcaac gcgatcattg atttgaaaat
     5641 cgttgtggaa gtcggattcg ttgttggagt tactccgcaa accacaccga ctggttcagc
     5701 aatttcaatc aacccttttt ggacatcttc attgatcaca ccaactgttt tatcatgttt
     5761 gatattatgc caaatatatt cggacgcata catatttttg attgctttat cttcgtaaac
     5821 accgcggcct gtttcctcta cagccatctt cgctaatggc atatgttgat ccaaagctgc
     5881 cattgccatt tcatgcacga tatggtctac tttttcttga tcaaagcttt ccatttcttt
     5941 caatgctgca tttgcttttt ctgccaaatc atcaatcatt gcttgtacgt caattgtctt
     6001 cgttttttct ttttctatta ctttagccat cattatcctc ctaatgggtc atggttattt
     6061 gttaaataat tcacatgtat atcatacaat atttattttt ctatgtaaac acttttttgt
     6121 gatttttttc acagttattt ttaaatataa aattgcttta tttacaggtg tttgtataga
     6181 aaaatatata aagttattta ttattattta tatgacacac ccgattattc aatattgagc
     6241 aatatatccc atgctcttat ctctttcttt tttgaataaa aaatgaggta ggacatcttt
     6301 ctgccctacc tcgtctttaa ataagctttg atacttattt ttcttccttc tcttctgtct
     6361 cttccagcgt ttctgttgtt tcagttttta cttcaactgt ctcagctggt tcttctgttg
     6421 tttcaacagt agtcgttgca tcatttgtta cgacagtccc tggtttgacc gttttgattg
     6481 ctgcacgatc gtactcaagg aagatccctt cgcagtctaa aacaactgtc cgtttgtcat
     6541 tgtcgatttc tgaaacaact ccatgtaatc cgccgatcgt tacgactgaa tcacctggtt
     6601 tcatgctatc taacaagttt tgacgttctt gctgttgttt cttttgcgaa cgtgacataa
     6661 aaaaccacat tgctaatagc gcgataaaca tcacaagcat tggtaatgtt cccatttttt
     6721 tcacctcact aattctgtat ctacaaaaaa cactttagca gaaaaatgct gataacacta
     6781 gttttttact taatttttaa aagattttcc tttagaagct ttttgcgttt tctttattga
     6841 acccgtattc ttcaaaaaag gcttctctaa attcaagcaa attatcatcc atgattgctt
     6901 gacgtacttg tttcattaga ttcaacaaga agtataaatt gtggtaagaa gtcaaacgaa
     6961 tcccaaatgt ttcatcacat ttgatcaaat ggcggatata ggcacgtgta tagtttttac
     7021 atgtataaca atcacatttc tcatcaattg gacggaaatc atgggcatat ttcgcatttt
     7081 tcactactag acggccttga gaagtcatac atgtgccatt tcgagcgatt cgagtaggca
     7141 agacacagtc aaacatgtct actccacgga taacaccatc gatcaatgaa tcagcagcac
     7201 cgacacccat caagtaacgt ggtttgtttt cggggatcaa cggtgtagtg aattctaata
     7261 cacgattcat ttctgattta ggttccccga cagataaccc gccgattgag taaccaggga
     7321 aatccatccc gactagatct ttcgcgcttt gacgacgaag atcttcaaac cctgctcctt
     7381 ggatgattcc aaataatcct tgacggtctg gattagcatg agctttcaat cctcgttctg
     7441 cccatcgaga cgtacgttct actgattttt tcacgtagtc gtaactttca tcgaatggtg
     7501 gacattcgtc aaaactcatc atgatatcag agcccaattt attttggatg ttgattgctt
     7561 tttctggtga taaaaacata cgcgaaccgt tcaagtgatt tttgaaatgc acgccttctt
     7621 cttcgatatt ccgcatatca cttaatgaaa aaacttgaaa gccgcctgaa tctgttaaaa
     7681 tcggttgatc ccagttcata aatttatgca gtccgccagc ttcttctact aagtcttcac
     7741 cagggcgtag ccataaatga tatgtattac ttaaaataac gccagcaccc atttctttca
     7801 actcttctgg ggacattgtt tttactgtag ctaatgttcc tactggcatg aacattggtg
     7861 tggggaaagt tccgtgtggc gtgatcaatt cccctaaacg cgcgccagta tgtttttctt
     7921 tcttgattaa acgatagcga atggcaggtt gcgtcattca tttccctact ttctatataa
     7981 aatatcttga caactcccac catcataatc gtttcaagtg ctttttgcaa gttccctcgg
     8041 cttccttcta ctttatttaa tattcttttt tttatccttt ttttatgaat aacaaaaaaa
     8101 agaaaaacat tatgacagaa atattttttg atacatggta tattggtgtt attaaagaaa
     8161 aggagggaaa aatcatgcaa tcttctgcag aattaaaacg ccaagcaaaa gagagtctaa
     8221 aaggacgttg gggacaagct gttttactaa atctaatccc tacattgatt ggtattgcta
     8281 ctattcttct tattatgatt cctattatct tgtttgccac caccatatat gatggatcag
     8341 cgagcgtctc agaagcgaca acttcaggag gcggtagttc aggaggcggt ggcggaatta
     8401 tttccagcat cattagcgct ttgttcatga gcggtatttc ttggacttat cttgatattt
     8461 tacgtggaca aaaagatcag atcgaaccat tcaaagatgc atttcgtgga ttcaaaggtt
     8521 tgtttatcgg cggagtgatc agcttagctg tgctgatctc gatctttaca acattatggg
     8581 gtttgctatt agttattcct ggaatcatta aaagctattc ttattctcaa agctatttta
     8641 tttactacga tatcgtccaa gaaacaggac aaacacctaa agtactggat acgatcactg
     8701 caagtcgaaa attgatggat ggttataaag gacaactttt ctggttagat ctttcattta
     8761 tcggctggca tatcttagca ttagcaactg ctggtattgg ttatctatgg ctcagcccat
     8821 acatttctgc aacaaaagca gcattttatg aacaattgcc aaaagatatt taaaagagag
     8881 tgtgacttgt gaccgagggg gtggcaggag aacaccgttt atcgagaggc agtaaaagaa
     8941 acattcagcc cattagcaaa aaggaggtgt gacaacattc atgtcacacc tcctttttgt
     9001 atagttccag taaaaagaaa atcaacttag aaacagttaa tcattcctct tcttctgctt
     9061 ccggtaatcg atggaacttg atcagttcat tcaccgcgat tggtacgata gataaaatcc
     9121 ctaccaagaa ccagtgattc aaactgatgt gtactaggcc gaatagttct tgcgtaaatg
     9181 gcagcaaagc aacagccgtt gtaatagcta atgccagtaa cgccatttct accaaagctt
     9241 tattggtcgc taaattgact ttgaagatcg attggctgct gcgtacattg aacacatgca
     9301 gaatcgatga ataagctaag atcaagaatg caacagtttg accgacatgc tgacttgcgt
     9361 ctacccatgg gctgatagta tcgacataac tacctaaata ataaccaaac aaggttacga
     9421 tggtgaagac ccctgcattt atggcaattt tttgcaataa acctcgagca aagatccctt
     9481 catttttcgg aatgggtggc tgatccatga tgccgtgttc cgctggctct cttcctaaag
     9541 caaatcctgg aagtccatca gcaactacat tgacaaacag tagttgcaca gctgtaaatg
     9601 gtgctcccca tcctaacagc atcgcaatca aaacaataaa gatctccgaa atattacagc
     9661 ttagcaaaaa gttgatagct ttacgaatat tctgataaac cgaacgtcct tgactgacag
     9721 cgtctacgat cgtcgcaaag ttgtcatccg tcaaaatcat atctgcggca ctttgcgcca
     9781 catctgttcc tgtgatcccc atggcacacc caacgttact tgctttcaac gctggtgcat
     9841 cattcacacc atccccagtc atcgctacga ctgcacccgt acgttgccaa gatttgacga
     9901 tccggatctt gtcttctggc gttacccgag catagacaga gagagctttg acacgcgcat
     9961 ctaattcttc gtctgataat tgatgcagtt ctgatcctga aagtgcttct gacggatcat
    10021 tcaagatacc taattctttc gctatggcac tggcagtcac cacatgatct ccagtgatca
    10081 tgactgtttt gatgccagcc tttttcgctc gcttgattgc tcctttactt tctggacgtg
    10141 gtggatcgat cattccgatc agaccaatca aacgtaagtc tttttccagt gcttcagaag
    10201 aaatatcttg cggttcttcg tcataagtag cataaccaac agcaatcact ctcagtgccc
    10261 gtttaccaaa gcgatcatta acgatcgccg cttgttctac atcgcctgaa ctaaagcgcg
    10321 gagcaagaac atcgaatgct cctttggtga ttgagatgta tttttcgccc atttggtgaa
    10381 ctgttgtcat catttttcgt tcagaatcaa aaggaagctc gtttactcgt ggatattttt
    10441 cttctaattc tgcctttgta tgataattct cttcaacagc ccttacgatg gctacttctg
    10501 ttggattacc tttgataaca aggtcgtcat cttcttgctc gaccgtcaca tctgtacata
    10561 gtgcagccat tttcaatatt tccatcgcgc tgttcgtcat tgaatcttcg atattcgtta
    10621 cttcatcttc tttgctccat acccggcgga cgcgcatttc attttgtgtc agcgttcctg
    10681 ttttgtctga gcagataaca ttagcggttc ctagcgtttc aactgctggc aactgtcgga
    10741 tgatcgcatg tttcctcgcc atcttctgca caccgtatgc aagtgtcaac gtaacaataa
    10801 cagtcaaggt ttccggtaca gctgcaacag ccaaggaaat cgaagtcatg aacatctcaa
    10861 ggagtggttc tccttgcagt tcaccaatca caaatactaa agccgcagcc gctaaagcga
    10921 tcatactgat tcgtttgcct agctgattca atcggacctg taaaggtgtt ttttgcatag
    10981 tattttcgtt caaaagatcc gcgatcttac ccatttctgt agccatgcca atggcagtga
    11041 cgatcgcttt cccacgacct gcagcaaccg tacatccttt aaataccata ttaagttggt
    11101 cacctaatga ctcatcttct tcagcaataa atgctgcatc tttttcaact gcttcacttt
    11161 ctccagtcaa cgccgattct tctacacgta attgtgatgc ttcgatcaaa cgggcatcgg
    11221 cagaaatagc atcaccggac tctaaaacaa gaatatcacc cactaccagt tgctctgact
    11281 caacagtggt cactttgccg tctcgtatga cagttgccgt ttgtttattc atatcttgca
    11341 aggattccag tgctttttct gcgtttcctt cttggacaat cgccaatacc gagttgatca
    11401 caacgatagc gatgatcagc agtccttcaa ataaatcccc atgttctgta gcaaatgcgg
    11461 tataaaagga aatcaccgct gctacaagaa ggatgatcgt tgtaaaatcg gacaagcttc
    11521 gaaagaattt tttgatcatc gattctttcg gcgcctcatc gaatttattc aatccctgct
    11581 tttttcgccg ttcatccact tcttgtgaag acaacccagt atctggatct gcttctgtta
    11641 ccttctttac ttcttctatt gtctgcttgt attcttccat cctattcctc ctttaaaatc
    11701 ttcgtacaaa aaaaggtact tattttacta taacatcctt tttttattta cttcaaataa
    11761 agggcttatc gattatttgt taagaaagcg taaaatttaa agtgcttata tttgcaaacg
    11821 ctaccaaagg atgctattat atagatgtaa ggaaggagga taccatcaaa tagacagaag
    11881 aatttctcga tagaacagtg taagcaaaca aagttgttag aagtacaggt ttcacccaga
    11941 catgcgtgta gagtacaaac ctataaatag tgaatgcgta tggatgtttg gatcacgaag
    12001 tatccgaaac aagaagtaat gcgatacgta acaattgaat aacgtaaacg tctgaaaatt
    12061 gaataggaac aagagatgtt tcaaatgttg aagatgtaac gaaaacaaaa tttttgttta
    12121 acatgaagaa attcaacacc gtgctttgca tgtatgatgg aaagttacaa tcatttctgt
    12181 ttatttgaat ccttccgagg tacaagaaag ccgagcttat cgagagctcg gctttttctt
    12241 tgtcataaaa tctttgtaaa gcttttttgt tattcaaaac tagcggcttt tcataacctt
    12301 atttcacgaa catcgcatct ccaaaactaa agaaacgata gcgctcttca atcgcatgct
    12361 ggtaagcaga taaagtcaat tctcttcctg caaaggcact aactaacatg actaaagtcg
    12421 attttggcaa atggaaatta gttgagaaag cttctaccac tttgaattca tagccaggcg
    12481 taatgaaaat atcagtccat ccgctgtctg ctttgatttc tccattaaat ttcgttccaa
    12541 tcgtttctaa tgttcgaatt gaagttgttc cgacagccac gattttcccg ccatttttac
    12601 gtacttggtt caatcgctca gccgcttctt ccgtcaaacg gtagaattca ctatgcatat
    12661 ggtgttcttc aattttatct acgctgacag gtcggaatgt acctaaccct acatgtagtg
    12721 tcagatagac taattcaaca ccctttgctt cgatctcatc aagtaattct ttcgtaaaat
    12781 gcaatccagc tgttggcgct gcagcagaac cattttcttt cgcatagaca gtttgatagc
    12841 gatctgggtc ttccagacgt tctttgatat atggaggcaa tggcatttct cccaatgatt
    12901 caagaatctc tagaaaaatt ccttcatact caaagtcaat gatccgtccg ccgtgttcca
    12961 attcttcttt cactactgct tgcaatctgc catcaccaaa agagattctt gtcccaactt
    13021 tggcacgttt cgcaggtttg atcaatgtct cccacgtatc tccttgtgta ttcgttagaa
    13081 gaaggacttc taaatgcgca ccagtatctg gtttttctcc atataaacga gcaggcagaa
    13141 ctcgtgtatt attcataact agcgcatcac caggctgtaa ctcttcaatg atttcatgga
    13201 aatgtttatc ttccatctct ccagttttcc gatccaaaac aagtaaacga gaatgatcgc
    13261 ggtcttttaa tggtgtttgt gcgattaatt cttccggcaa gtcaaaatca aaatcttctg
    13321 ttgttaacat atcgtcactc actttctatc atgtgcttca tcattctatc atgtttttcg
    13381 ttctgttggc aaaatcagca ctttttcact tctatttttt gttttcctaa ataaaaaaac
    13441 taccctattt gtattttttc attgttttag gcatactagt aatagatagt tcttcattga
    13501 aaatagaaaa agaggtggca ccatgattga atttcaaaat gtgtcaaaaa tttataaagg
    13561 tggaaaagtc gctgtagagg acgtcaatct ttcatttgaa aagggtgagt tcatttgttt
    13621 tatcggtacg agcggaagcg gaaaaacgac gacgatgcgg atgatcaacc gaatgactga
    13681 tccaacacaa gggaaaattt tgattgatgg aaaatccatc caagaaattg atccagtgga
    13741 attgcgacgt cagatcggct atgttatcca aagtattgga ttgatgcctc acatgacgat
    13801 ccgtgaaaat atcactcttg tccaaaaatt gttgaaagtc agtcaagaag aacggaataa
    13861 aacagctgaa aaaatgattg atcttgtgga attgccccgt gagatgttag atcgctaccc
    13921 acatgaatta tctggtggtc agcagcagcg tattggagtc gttcgtgccc ttgcagcgaa
    13981 tcaagatatc atcttgatgg acgagccatt cggtgcgctt gatccaatca ctcgtgattc
    14041 cttgcaagac cttgtcaaag atttacaaga gcgtttggga aaaacgatcg tatttgtaac
    14101 ccatgacatg gatgaagc
//
LOCUS       DAYNVV010000065        13945 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.068, whole genome shotgun sequence.
ACCESSION   DAYNVV010000065 DAYNVV010000000
VERSION     DAYNVV010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13945
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.068"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            137..310
                     /locus_tag="ACGXWR_002270"
     CDS             137..310
                     /locus_tag="ACGXWR_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803796.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            950..1423
                     /locus_tag="ACGXWR_002271"
     CDS             950..1423
                     /locus_tag="ACGXWR_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HFK0803797.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1432..1659
                     /locus_tag="ACGXWR_002272"
     CDS             1432..1659
                     /locus_tag="ACGXWR_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0803798.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2295..2666
                     /locus_tag="ACGXWR_002273"
     CDS             2295..2666
                     /locus_tag="ACGXWR_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803799.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2922..3164)
                     /locus_tag="ACGXWR_002274"
     CDS             complement(2922..3164)
                     /locus_tag="ACGXWR_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFK0803800.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3196..4098)
                     /locus_tag="ACGXWR_002275"
     CDS             complement(3196..4098)
                     /locus_tag="ACGXWR_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFK0803801.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4111..4299)
                     /locus_tag="ACGXWR_002276"
     CDS             complement(4111..4299)
                     /locus_tag="ACGXWR_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFK0803802.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4313..4876)
                     /gene="amaP"
                     /locus_tag="ACGXWR_002277"
     CDS             complement(4313..4876)
                     /gene="amaP"
                     /locus_tag="ACGXWR_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFK0803803.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4914..5807)
                     /locus_tag="ACGXWR_002278"
     CDS             complement(4914..5807)
                     /locus_tag="ACGXWR_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFK0803804.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5885..6808)
                     /locus_tag="ACGXWR_002279"
     CDS             complement(5885..6808)
                     /locus_tag="ACGXWR_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFK0803805.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPIYFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6857..7207)
                     /locus_tag="ACGXWR_002280"
     CDS             complement(6857..7207)
                     /locus_tag="ACGXWR_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFK0803806.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7240..8142)
                     /locus_tag="ACGXWR_002281"
     CDS             complement(7240..8142)
                     /locus_tag="ACGXWR_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFK0803807.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8135..8992)
                     /locus_tag="ACGXWR_002282"
     CDS             complement(8135..8992)
                     /locus_tag="ACGXWR_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFK0803808.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9326..10135
                     /locus_tag="ACGXWR_002283"
     CDS             9326..10135
                     /locus_tag="ACGXWR_002283"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFK0803809.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10175..10672
                     /locus_tag="ACGXWR_002284"
     CDS             10175..10672
                     /locus_tag="ACGXWR_002284"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HFK0803810.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(11057..11130)
                     /locus_tag="ACGXWR_002285"
     tRNA            complement(11057..11130)
                     /locus_tag="ACGXWR_002285"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11094..11096),aa:Ile,seq:cat)
     gene            11317..11640
                     /locus_tag="ACGXWR_002286"
     CDS             11317..11640
                     /locus_tag="ACGXWR_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803811.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            11804..12058
                     /locus_tag="ACGXWR_002287"
     CDS             11804..12058
                     /locus_tag="ACGXWR_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803812.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            12128..12373
                     /locus_tag="ACGXWR_002288"
     CDS             12128..12373
                     /locus_tag="ACGXWR_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFK0803813.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            12449..12814
                     /locus_tag="ACGXWR_002289"
     CDS             12449..12814
                     /locus_tag="ACGXWR_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02328 family protein"
                     /protein_id="HFK0803814.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(12875..13438)
                     /locus_tag="ACGXWR_002290"
     CDS             complement(12875..13438)
                     /locus_tag="ACGXWR_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803815.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT         4088 a         2577 c         2303 g         4977 t
ORIGIN      
        1 tttttcggag aattaaaaaa tacaataaat aactttagtt actttaatgc gttcttactt
       61 tatttttata ttatcatttt tcttattcac ttctttggtt tatactattc ttataaataa
      121 aaacgaggta tgtcctatga tgaaaagatt gtactattca ttgatcataa cgattggcta
      181 tttgattgta tcaaatctag gaaatatggt atttggtatc agtaaagaat tcagttggac
      241 tactacatta tgggaatctc tattcttttt catcttcgta tttttgttac aaaattatcg
      301 aaaaaaataa acatgtgcca tctatctgtt ggcacatgtt ttaggattta tggtactttt
      361 tattcggcaa tccattttat ttttctactt cttcttaata cctctaacac ttttgattta
      421 taaactaatc caatgcatct acttgcgctt attaagctat ttcagctaga tagtaccacc
      481 ccatgcgtca atgcttgatt ttccttttgt ataacattgt ataagcaata aaggacaaat
      541 aagtggtgat tacaccaaac cattgaataa gaaaaattct gatacgtaaa taaacatgaa
      601 cttgaaaaaa ttaatgaatc ggttagctac tacgtagttg tcttttttct catacagttc
      661 tgttaactta cacttctctt cgctagataa taaaaaatcc tccaactgta ttgtccaata
      721 taatcccagg catctaaact agcattatag aagagacaca catagaatct aaaataactg
      781 gttttaaatg tttcttacaa tcaaaaaaag ctgttaaatg cactccacac cttcatactc
      841 tatcattttt tataaacgat atatttttat tgtttttcga taaaaaatag ttgttttaca
      901 ataattattc tgctatattt tagctatcaa agataaaaga gggataaaaa tgaaatttaa
      961 aacattgcta ttaaaatttg tcgttttagg tataagtgcc gtatttattt tgttcggcgt
     1021 acttttttat actcagatcg ctacaagcga aaaaggattc aattttgatt ggcagaccac
     1081 attatttgtt tctgtcattt actttgccct tctcctaggg atcgttattg cttatttctt
     1141 attgaaacta ttgaaaaaaa tcgaagataa ccaagctttt tccactcaaa gcttaaacat
     1201 actaaaaaaa atcgaacgaa ccattttgtt tattggtttc gccttttttg gcttacttcc
     1261 taaatttatg aaagtagcgg atttagacga tgctccaggt ttgatgttgg taggaatcgc
     1321 tgtcgtattc attccttttg cagtatacac attaacaagc gtgctggaaa aactgcttga
     1381 acatgcgatt ttacttaaga cagatcatga tttgacagtg tgaggtgcga catggcaatt
     1441 atcgttaatt tagatgtagt attagctcaa aaaaaaatga gtgtgactga attgagtgag
     1501 aaagtgggca ttacgatggc aaacatctct attctaaaaa atggaaaagc aaaagccatc
     1561 cgtttttcca ctctcgaaaa aatctgccaa gttttggagt gtcaaccagg tgatttgttg
     1621 acctataaaa atgactcgaa tactatacca gaagaataaa ataaagtaga acaaacagta
     1681 aataaaaaat aatctgaatg atagatgtgt gagactttta gaagttattt acgtctatta
     1741 ttcagatttt ttatttcgat tgaataccgt tttatctata aataagatat gtactgactc
     1801 atacaaaggg ggccttttct tctccatgta ctatcacttt tcctgataca actggtttcc
     1861 tgttacgttg tagttggatc tgcttttagt ataatacttt attcattcca ccagactgat
     1921 agcagtttga gcagtctaaa taatcatgta gtattacagg ccattctgtt tcataccttg
     1981 aagtgcttaa aacttcagct aatggcccat tgtgttaact cttactccat tcttttttag
     2041 taagctccca tatatactgt aaagccttct atatattatg tcatgttgct ttttaacatt
     2101 tactatgtag ttttgataaa atgatttgaa taacagtgat ggacaattct tttttatttt
     2161 taacattatt ttgataataa tgattattta tttaaaaata cattagataa catttgttac
     2221 gacacgaaaa agcttcacaa acaaatatcg ttattttaaa atgagggcga actcacacaa
     2281 ttaggaggaa tagtatgcca tttattgttt acttttttct ttcattactc gtgatctata
     2341 ttccattacc aacatttttc ctgctcgtca atcgtctagc agagcaacat gatacgattg
     2401 ctgctcttac gaaactttgt ttacttctat ttgtttgtct agattacttt acgagctatt
     2461 attggctaaa acagacaaga gtaaaaaaga gatattattt cttccttgtc tttttcaatc
     2521 tctttgagtt tctgatccat tgctttttac ttcatcagta tcatacgatc catttgtgga
     2581 tcatctgggt tttcaaagtg gtcgtattat tttgtatgtt cacctttcct atctcaagaa
     2641 aatttaggga ggcattgttt tattaaagaa gcttctctgt atcaataaag acacatttaa
     2701 ggaaaaactt ttaaaaatct aattgggaat ttgcccgcat aaataagagg ctgtgacaaa
     2761 agtcttgtca cagcctctta ttccgtataa acagtgttca aaagcttgca tcttcgataa
     2821 tatgcccaac caaatgaaaa atatgagaag ctatttttgt ttggctgttc ttattacttg
     2881 atgaagaaca gctttttcac gacctctttt taaaagtctt tttacagttt tcgagcaaag
     2941 aatgatacga ttagtactaa aatgatggca ccaatcaatg atggcacgat tgccattcct
     3001 gcaatacttg gtccccaaga acctaataat gcttgaccaa gtgctgatcc aactaaacct
     3061 gctacgacat ttgcaataat ccccatcgaa gaacctttat tcgtgattgc tcctgcaatt
     3121 gctccgataa ttcctccgac gataagtgac caaataaatc ccatgtttcg ttcctcctaa
     3181 tgttttactt ccttattact gaacccgtgg ttctgtattt tcttttactt tttgtgcgcc
     3241 gcttccagct gctgatttta ctttatctgt ttgattcgaa gcaaattcac cggttttttt
     3301 cgctgcgtca gttactttgt cttgcaccgt ttcttgatct ttttcaaatt cttcttttgt
     3361 tttgatgtcc actacgttag cgttgacttc gatcacttct aaatgtgtca tattttttac
     3421 ttctttgccg attacttctt gcatttcttc aaagattttt tcgatatctt tgccatattc
     3481 cacaatgaca tccatatcaa ctgctacttg ttttttaccg acttctgttt cgatcccagc
     3541 cgttacatta tctgtattca caagttttcc tgccacatta gagaagaaac caccgtttgc
     3601 agataataaa ccgtctactt gttcaattgc gattccgatg attttttgca caactttatc
     3661 ttcataattc agctcaccgc gcattgaatc ttcctgttca gaatcatgct ttccttggtt
     3721 atttgtatga tcagaaccaa gttttccttg tccgtttgtg tggtcagaac taagtttttc
     3781 ttgtgctttc gcatggtcag aaggatgttt ttgctcttcc acaggtttag aaggatcgat
     3841 tgcatcatgt tgttctggaa ctttagattc tggagttcct ggatgatgag gtgcatgctt
     3901 ttctgcatca tgtttcttct cttctactcc ttgttgaacg ttagggacta ctggatctgg
     3961 atgtgcagat actggtgctg ttttgttctt ttcatcgttc acaccatttg attggtttgg
     4021 tgtcgttggg tctggatgtg cagacactgg tttttggttg ttcattttat tgttattatt
     4081 tttgttattg ttattcatgg atgtttcctc ctaagattta aaatagtgat ctaagatttt
     4141 cgtttgtttc agataaaaac cgatagcgac gccgatcgct gccatgatca agatcaataa
     4201 ggtcttgaaa aagcccacgg tgatccataa aacggctaat atcaatccaa gtaccccaaa
     4261 gatgataggg agcttgtatg tcgaaaatag ttctttcatt tttggtcccc ccctattcta
     4321 ctcgtttgcg gtcattgctt cgtttagctg gttcttcaaa gcctgtgtat ttcaccgata
     4381 ctttcactgg ctcttttgtt cccaatatgt gttgtacttc attttcgatt tctttcatca
     4441 atgttcctgt tttaccaatg agtgctgaag ttcgtttcaa ctcccctttt acattgacgg
     4501 cgatcttgtt tttcgttgct ttgacattta cttttggtga atggatgaat tcatcttcat
     4561 gcaagtgaga acgaaccatt ccttcaattg cttttttatc caacgtcaac tccccatcac
     4621 catgtttcag tagaaagttt ccgattgttt ttggataaaa caggaaaaca agtaacgtga
     4681 taattgtcaa aatagcaaat gcaacggcaa gccaaaatac atattgttgc acgtatgaat
     4741 tagtgatgga aaagaatcga aacttctcta gctgaaaagg caatggatag gttgcactta
     4801 atagtatcgc aaacaaaagc acagatagca aaagtaatgt tccgatcact ccgatcgttt
     4861 ttacaccttt attcattttc gcacctcctc ataggggtga aacgatcaac ttcttataag
     4921 ttgatcgctt ctccaccagt tactccgtaa atttgggctg taacataact tgctttattc
     4981 gatgctaaga aaacataaac tggtgctaat tctcctggct gacctgcacg ttctagtaaa
     5041 ctttgctgac caaattcagg gatcgaatca gaaggttgtc cttcgtctag ttgtaatggt
     5101 gtccagattg gaccaggtgc tacaccattt acacggattc ctttaggtgc aagctgtttt
     5161 gctaaaccga tcgtaaagtt agcgattgaa gcttttgttg ctgcgtaatc taataaatgt
     5221 tcgcttggat tgaatgcttg aacagaagtt gttgttacga ttgctcctcc tgctgggata
     5281 tgcggaacag cttctttcac taaagcaaac atagcgatga tgtttatcat aaatgtgtct
     5341 ttgacttgct caagtggtaa ctcagcaata gactgacaag aaatttgctg tcctgcgttt
     5401 agtaccatcg tatctagccc gccaagttca ctcacggctt tatctatgat ttctttaggt
     5461 gcttgttcgt cacgaagatc aaaaggtagt aagacaatct tacgtcctgc atctttcacg
     5521 tattttgcta cttcctctgc atctttttct tctcctggga agaattgaag agcgatatct
     5581 gccccttctc tagcaaatgc aatcgctgct gcacgaccga tccctgaatc tccaccagtg
     5641 attagtacac ggcggttttc tagttgatta ttgccttcat aggattcttc tccacaatca
     5701 ggaacaggaa tcatattctg ctgtaaagct ggtgtatcct gatcttgttt aggaaatttc
     5761 tccgtatggt acaagtttcg cgggtcgatt aattttggtt ctgtcattgc tgtattcctc
     5821 ctagttttta aattgtattg ccaaaacaaa tttctttgtt tgatacctgt tttaaataga
     5881 ttctttaatt tgtataatct ttccggtata aatggtaacc taaaactact gctgctatca
     5941 aagagccaaa gactacgagt ataaagccta gagcagaact tttacccggt aatcctcctg
     6001 tattcattcc ccaaatccct gcgaacaacg ccggaacgga aatgattaat gcagctgaat
     6061 ctagatattt catgatatga tttagattat tgtccatcat cccgttgaat agatcaccaa
     6121 tactctctaa taaatctcga tagatctcga tcattttttc tgtttgtcgc tgtctcaaat
     6181 ggacatcata gagtagctgt tcatcgtcta aacgtttgat gaaagtttca gaattccata
     6241 attgatccat tgtttcccgt tgatctctta aggtatgatc gatatatacg atgtctcttt
     6301 caagatctgc ctgtttatac agttcttcat tttccgttgt tttacgagct gctttatcca
     6361 aagcgtcaat tcgctttttc atctctctta gttctttcac gtaatgggtg taaatatcta
     6421 ataatgtata cgtgatgatc ttttcaaacg agtttaaatg atttccatgc tttgtcagca
     6481 gccgatccac aaattcggtt tttctatcga tacaagtaat caagagatta tcggaaagta
     6541 caaaatatat tggcgttaat tttttttcga tacgattatc tgactgatct agattaatca
     6601 ctaccaaaga aaatggatgc tctagtttcg tctcataaag gcgctccatc cgagaaactt
     6661 cttccggata ttcggttcct acgaaaatat catcaggaag ctcgaattct tcgattgctt
     6721 gctcaatctc ttcgggcttt gcactatcaa gtacgagcca attatatttt ttttcatctg
     6781 tttctattac attcttttct tcatccacaa agtagtatct caatgtatac ctcctttttg
     6841 gactttctcg aaactattag ctgaagaagc agttctttaa tttgatatta taatcgagta
     6901 ctgcgatttc attttctaat gaaaagctgt caagctgttt gttgaagtcc atgttcaatc
     6961 gtttaccgaa ataattttgc tctaatttag atgtatagat gtccaataat ggatgctcga
     7021 ttttagtcgc atattctcca aattccgaaa caaaaggaat gatttgaaaa aagctgcctt
     7081 ttgcaaaagc acctttgtcc cttagaaatg gatcggaatc attgataagc gcgagtgcga
     7141 tttttgtatt ttccccaacc ttttcaatta acgtctctac tgcattttta gacattgtaa
     7201 tttccattcc tactccccct cttcagttgt tgtcttctat tatttaacaa ctacatctgt
     7261 ttttggttga acttttgcat attttggata tttagggaat ttagctacac aacggaaagc
     7321 cgtcatccct gcatattttt cgtaatattt cttcgttggc ccttcaaaat ccttgctcca
     7381 cggtttcaca tgtcctgaaa aatggataat gtaaggattg ttgcgagttt cttcgtattc
     7441 acgttcacct gctgctgttg gatgtttttt tgcttttgcc atgatatagc cttgtgcatt
     7501 ccaacgcgga tgaagtggta accaacggtc atgtaagata gcatttaatg catcttggtc
     7561 atggaatcgt aatttttctg gattatgttc gatgaaatct aatacttttt gcgtaatatt
     7621 ttcatctaac cattttttca cattgatcag catcaaacct gagttgaaat aacgcattga
     7681 tttagctgaa attttcattt tttccagtcg ttgatggaac ccagcgtctt caacagctgc
     7741 tacgattgaa tcaccgaagt caagacgcca taatttagag atatcttgta aagcgatcat
     7801 gtcgcaatcc atatataaga tacgttcaac ttctgtgccg cggaacaatt ccggaatcgc
     7861 aatacgataa taagctgttt ctggaatacg atcgctgatt accacatttg taaagaattc
     7921 tttattgatt ttcaagaatt ccacatctga gttcattcgt gcgtttttca ctgagaagcg
     7981 taaaagctgt ttactttcaa aatcgatatc atcgtcaatc acatagaacc gaacaaattt
     8041 agacgggttg caattatcta atactgagac aaataatgca gctaaatgtg gtacgaattt
     8101 tgtgttacaa cttgcgacta ctgctatttc ttttttattc attgatctcg cctactttcg
     8161 ttagagtact gtgtgctaat ttttttaagt ataaattggt atacggatga tctttcaacg
     8221 tattccaagg tttatcatgt cctgtaaagt gaacgatcga aggtttttca tttccttctt
     8281 tatactgacg ttcatatttt tcatttggtg ctggatgacg ttcaaaaatc agcgaagtct
     8341 gcatgttcca ttttggatga agttgttccc aatcttcata aagtacagca ttcaaagcat
     8401 cttggtcgtg atagatgatt cgatcgccat tttcactgag gtaatggata gttttttctg
     8461 taatttcttt tttattccat tgatcaatgt caatcaccat cactcctgaa ttgaagtaca
     8521 agtcatcgga atcgattcct aatctttcca aagctttcac ttggcctgga tcgataatag
     8581 cgccgattgt ttttccattt aacggctcat catatagttt tacgatatcg tctagtacta
     8641 acacatctga atctaagtaa aggactttct tataatcctc tttagctaat aagtttggta
     8701 aagaaattct taagtaagcg gtagttgtga tatggtcact gactaggaag tcttcgtaga
     8761 tatctttttc cactgtcagg aattggatac ttgcattact tgaatattta tttaccgttt
     8821 cttccaatcc ttctttacta tattctgata gaccatcgtc aatcacataa aattttatgc
     8881 gtcttgtttt attgcaattt tctaatgcag ttgcgatcat cacgctcaag taaggagcat
     8941 aattttcgtc tgaagcagtt accacaggaa ctacgccgta tctcttctcc atcaaaatca
     9001 ctcctttttc taatcttttt ctaacctgtt ctacatctag aatattcctc atttggtttt
     9061 aaagcaaaat atatgctttg ttttcattga atattttaaa atttttttat cacaaaacgc
     9121 atcggtaagc gctaactatt cgtttttcat ggctttttat tcaaaggtat tgaccaaaaa
     9181 ctactatata tagccacctt tttcttaaga atgttttttg aaaaaattca taatgacaaa
     9241 gcaagttagt ttcatttttt taaattctca tttaatctta aggtaacagg aaaatagata
     9301 tgtaaaaaga aagtaggaag ataaaatgaa actagcagcg attgatttag acggtacctt
     9361 gcttgatcga aatggaaaga taccagaaga aaatatccaa gcacttcgga aatttgatga
     9421 aaatggcgga atcgtaaccg tcgctaccgg aaggaacagc atttctgcta aagatatttt
     9481 ttccgaatta ggaatcggtg gctatttgat ttcttccaat ggttcactga ttgctgaaat
     9541 gaaggatgga aaaatggcga aagttctcag acgttcaaaa atagatagcg atacactgag
     9601 aaaagccttc ttctatgctc aagaagcgaa aatatccatc attgctagcc gagaaaccca
     9661 agatgatcag ctgacattcg atgaatcaaa tctagtcaaa gatgaccctt attatgaaca
     9721 tttcaattta cagaaccatt cttttgatca aattttaaat atgttggaag atccttctct
     9781 tagctatctt aaattagcat taacagataa gagtgaagaa aaactacaga agctacaaag
     9841 agatctgcaa gcagatggta tccaatcagt attctctgat ccgcatttct tagaaatcac
     9901 gcctacaggt atcactaaag ctcattcact tgtttttctg gcggattacc ttggaatcga
     9961 atcgagtgac atcatggctt ttggcgatca agaaaacgac attgctatgt tgaattacag
    10021 cgggttgagt attgcgatgg ggaatgcaca gcgacaagta aaagaaattg caaaccaagt
    10081 aacactgacg aatgaagaag ctggtgttgc ttatatttta aaaaacttct attaaaaaga
    10141 ataaaatgac gatatgaatg taggaggaaa gaaaatgtta gttattattg atatgcaaaa
    10201 tcatattctt gatccaaaca gcgaatttta tattccagag tcagatcaat tggcagaacg
    10261 tattgctcaa agattagcta aagcacgcca aaataatgaa tatattctct tcacacggga
    10321 tataccagtt gaactgaagg acaaagaaga agaacgagaa gatttgcaat tgatccctct
    10381 tctttctcca caagaaaatg aacgagtgat taaaaagtat tactttacga ttccacctga
    10441 aactttagct gaaatccagg aaactttatt tgaaagcaaa gaagaacaaa aagagatcga
    10501 agtagtcggg attgaaacaa acttgtgtgt actctctaat ctgataggcc tgcagagtgc
    10561 ttttcctgaa gcagactttt ttgttgatcc aatgttagtc tccagtagaa aacacggaga
    10621 atccgcttta gagctgttga aagatttcaa cgtctctatc gtcgaatcat aaaaatatct
    10681 atcttcattt acgatattta acacacaata aaaaaagcac gcagaactgt tttagtccta
    10741 cgtgcttttt ctatcaaagt agattggctt ttttatgaca cagagtgaaa cggcaggctc
    10801 acgacctctt tcttaaatgg tgttcaatca gctgaccctc ggtattagct taacaaacgg
    10861 caaaatatga ggaactattt ttccgtttgt taagctaata ctcaggtcaa aacgctgatt
    10921 tcacaacctc ttccttaaac ggtattcaaa agcttgcatc tgcagtaata agaacagcca
    10981 agtaaaaaca taagaagctg tttttacttg gctgttctta ttacttgatg cagggcagct
    11041 ttttcacaac ctcttatgta ccttgtagga ctcgaaccta cgaccggacg gttatgagcc
    11101 gtctgctcta accaactgag ctaaaggtac atcataaata aaatttattt ttgttacttt
    11161 tcaactatag cacgaatgac aaactctcac aagtttcaaa atataagtaa aataatattg
    11221 ttattcttat ttcttttact tgtgtcataa ctattttgtt actttaattt ttatttgctt
    11281 attttagaaa aaatgttatt cttttattta ttctcaatgt taggagtgat tattttgcca
    11341 tttattgcga ttttattcga tttagttgcg gcagcagctt attttctcca attaaattat
    11401 caaacctcag gaattctgtt tattggaatg atttttcaag gtgtgattac ccttttgctt
    11461 cttgtcatga tgctcagcta taaaggaaaa agatatgccc gtattcaaac aaaagtattt
    11521 gttaaatatg tttccattcg ctatgggatc atcattcttt cctttttagt gaatgcgatc
    11581 gtcctctttt tatatgtatt gaattactta gatatcaatc cattgatttt ttctcgatag
    11641 ataagacaca ttcagcggaa cagttcctgc ttatcagcag aaaactgttc tgctttttca
    11701 tttttcattg atctattctt cttttatttt cctagcattt catttgtgat gtatgcaata
    11761 acatgttatc ttttattata tgaatcgttg aggagtccgt tacatgatta cgttggtgag
    11821 agttttgttt tgggtgcctg cggtcgcact ggtcgcaagt attgtttatc ttatgaattg
    11881 gaacaaagaa cggttttatt tagctatttt gactcttccg gctatctact ttatgtggaa
    11941 agtttttaat tacaactact ttgaacccga tagtgttttt atagaagaat tatcaggact
    12001 ggttttgtct ttattgatcg tcattcttta tttgatacgt ttaaataaaa aacattgagt
    12061 actattgatt gcatgtgtag ctttctatag tcattataac tattctacta taatgaaagg
    12121 tgattaaatg agtatcgaag aagctatttt actggatact ttacgttgtc gtctgaattt
    12181 cttaagaact ggccgatctt tatctcaagt agctgtttct agcgcgttaa gtattccttt
    12241 attcaaatat cgtaagtacg aagaaggaga agaaattcca agcatcattg aattaatcta
    12301 tatcgctgac ttttacgata tttccgttga ttacctaatt ggtcgctcag aaacagcaag
    12361 caaactgaag tgattttttc cagccttggt gctggttttt tcatttaacg tctaaggtta
    12421 acaatctata tataaaggag acatttctat gcgattatgg catgaaaaat tgatttcaaa
    12481 gcttcctcgt caacagcttt taggacaaca tcgggaatgc tgtgcattaa gaggaaatgg
    12541 ctggggaaag aaacatgcta ctgtggatta tgtttttcac tattctcctt atagattatt
    12601 ccaatatcat cagcttgtca tggatgaaat ggaaaaacgt ggttacagcc cagcaccaga
    12661 gtggaaaaat cctatgtatc gtggcaaatc atgcgaagca ttttttgatt tacctactgt
    12721 agagcgcaac gtgccgattt atccggaaca cgatgaagtt tatctagcag aatgtttagc
    12781 aaatttggag caaaaaggaa tttatcttac ctaatataac tagaaaagcc ttctatctcc
    12841 tcttacttca ttaaaaagct ttaaccatct tagatcaagc taaaatgtcg taagttttag
    12901 ggttatcttc atcctcacgt gcaaaactaa aagcgtactc tagttttggt tcatcgccaa
    12961 cttccctaga cataaatgaa catctcctga cgtggtttaa aagtaccgca tcttcgacgt
    13021 ctgtatacga tgcacagcac agattgcttc ttttgatctt tcttttgatt tttctgttgc
    13081 ttcttctaca ccttcttcga ttactacatc gatgcttaca attgcttctg cctaatattc
    13141 ccatgcatcg tcgatttaag cctctgtagt cactgtgatc gtttccacat tttaactcct
    13201 ctgtcgtggc ttcagttgat tttgtgatca gttcagttgc taagccagag tcagaacaac
    13261 ctgccattgc tagcgttaat attgatagta aaaatagttt ttttatcata aggttccccc
    13321 cctgaaaata gactaaaata ataacgcttt ctttttttgt tttcagacga aaattaataa
    13381 tttctaaata ttctttaaaa aagcttataa ctattatgcc ttttttaata tataacacag
    13441 ttatttttaa aaataagaat gctaaatcac tctacaataa cggcgaaagc acaaaaaata
    13501 aaaaaattat tacgttatta aaaaaacaga tgaaagatca ggttttatta gatctcattc
    13561 tttcatcact tgaagggatt taatgaacta ctttttcctc tttgtcgttt ttatatattc
    13621 gtattccttc aaacagtagg atagcctctt tcaatgcttg atatttgaac tgtccgttac
    13681 ttaaaaattt agatgtgccg ccctcttcct agaacatatt cttttttact ttttcattaa
    13741 ttgacagacc aatcgaacga aactgtaaat ttcgatagga taatgattgg tcaaactcat
    13801 tcattttcaa gacatctcga ttcatattca agataggaat ctttttatca acatcacttt
    13861 attcgtattt tcctctacca taaaagcttc acgctccaca aaattgtttt atacactact
    13921 attcagccca ttcaacgacc aatga
//
LOCUS       DAYNVV010000066        13784 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.069, whole genome shotgun sequence.
ACCESSION   DAYNVV010000066 DAYNVV010000000
VERSION     DAYNVV010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13784
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.069"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="ACGXWR_002291"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="ACGXWR_002291"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HFK0803816.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="ACGXWR_002292"
     CDS             complement(1172..1867)
                     /locus_tag="ACGXWR_002292"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HFK0803817.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="ACGXWR_002293"
     CDS             complement(1880..2596)
                     /locus_tag="ACGXWR_002293"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HFK0803818.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3531
                     /locus_tag="ACGXWR_002294"
     CDS             2926..3531
                     /locus_tag="ACGXWR_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HFK0803819.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3856..4179
                     /locus_tag="ACGXWR_002295"
     CDS             3856..4179
                     /locus_tag="ACGXWR_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HFK0803820.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4361..5731
                     /locus_tag="ACGXWR_002296"
     CDS             4361..5731
                     /locus_tag="ACGXWR_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFK0803821.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5861..7162)
                     /locus_tag="ACGXWR_002297"
     CDS             complement(5861..7162)
                     /locus_tag="ACGXWR_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFK0803822.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7392..9383)
                     /locus_tag="ACGXWR_002298"
     CDS             complement(7392..9383)
                     /locus_tag="ACGXWR_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HFK0803823.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9527..9793)
                     /locus_tag="ACGXWR_002299"
     CDS             complement(9527..9793)
                     /locus_tag="ACGXWR_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFK0803824.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="ACGXWR_002300"
     CDS             complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="ACGXWR_002300"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HFK0803825.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="ACGXWR_002301"
     CDS             complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="ACGXWR_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HFK0803826.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13137..13700
                     /gene="def"
                     /locus_tag="ACGXWR_002302"
     CDS             13137..13700
                     /gene="def"
                     /locus_tag="ACGXWR_002302"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFK0803827.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
BASE COUNT         3946 a         2881 c         2544 g         4413 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcgaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 agcacaggtg aaggtggcga accagaagtg atcggttcaa cagaagaata atactgaaac
     3541 aatcaggtgg tgttagaagc ggcgggtcag cagcttttaa cacgcctttt ttatttctaa
     3601 tcgtttattt tcatatgggg cttccacttt tgtaaatggc tttacaaacg aaaaatccta
     3661 atttaccaag cttttcctcg catactttta tcgtaccttt ataaaaattt atactttgaa
     3721 aaaaagtatt caattattgt tgcatttttc ctgattcttt attagaatga accctcgttg
     3781 aagtaagtat ttctagttta tcctaggatt aattataaaa ataaaacatt cgttgattcg
     3841 aaggaggtta aacagatgtt tgaaagtttt gatagcagcc gcaaccgtta cgcttcagtt
     3901 ggtgtcgtat caagtttgcc agatgaattg attgacagta tatggtttat tattgaccta
     3961 gatcttaagg gagtcattcc attagaaaat atattaacct ttgatttgat cgaaaatcgt
     4021 ggaaaagtga cgatgcattt ttctcaagca ggaagcaatg tggaaatgga tattgatttg
     4081 ccgtttgcct attcgaacca atttcctgct caagtatacg cctatgatga cggtacgaga
     4141 gaaacgatcc ttttaccaag tgagattaga caatattaag gtgatagata aacgtggatg
     4201 tcccttattt tacagaccag gccaagttgt tgattctttg actcaattct tggcttcttt
     4261 ttatggagtt tcataaatta tcattgattt ctaattggta ttctcaggat aaacgctata
     4321 tactactaac taaattttaa agatataagg agtttaaaag atgcgcgatt taacaaaagg
     4381 aagccccgct aaactgattt tgatgttcac tgttccttta ctgatcggaa atgtttttca
     4441 gcagttctac aatatgatcg atatgatcat cgtgggtcag acgctaggta aaaatgcgct
     4501 ggcagcggtt ggtgcaactg gaagcctgac atttttgatc attggctttg cccaaggttt
     4561 aacagctggt ttagccatta ttaccgcaca acgttacggt gcaaaagatt atcggggtct
     4621 gaagaaaagt tttgctgcta gtgttgtcat tagtcttgtc gtcactgtga ttttaactgt
     4681 cctaagtctc ctgtttattc gtccgatgct tcaattgatg caaactcctc ctgaaatact
     4741 tgatcaagca caaacattta tttcaattat tttattaggg atctttgcat cagtcagttt
     4801 caatttgctt tctaatgtca ttcgcgcact tggtgacagc cgcacaccac tattctttct
     4861 gatcattgcg gtcatcatca acgtcgtact tgatttgatc tttattatct attttggcat
     4921 gggtgtggaa ggtgcagcta ttgctacagt aatcgcacaa gtttcttcca gcgtactgtg
     4981 tctagtgtat atcaagaaaa aaatgccttt gttacagtta cgcaaaaaag atttcaaatt
     5041 tgaaaaagaa gagtttgctg tacacctaaa tgctgctttg ccaatggcgt ttcaatcttc
     5101 gatcatcgct gttggtgcta tcgtgttaca agcagcacta aatagtctag ggacagatgt
     5161 cgtagctgct caagccgctg ctggtcgtat cgaccaattt gcaaatcagc cgatgatgtc
     5221 atttggtatt gcaatggcaa ctttcactgc acaaaactat ggtgcgaaag aatatggccg
     5281 aatcttgcaa ggggtacgtc aaactttact gatgagtgtc ggatttagtc tcttagcagg
     5341 tgctatcgtc attttcttcg gtcatttctt tgttcaattg tttgttagcc catcagaaac
     5401 acgtgtattt gaattagcac aaacctactt caatatcaat gggtctcttt actggatctt
     5461 agcagtcctg ttcattttac gctacacact tcaagggctt ggacaaagca agatccctac
     5521 gatcgccggt atgatggaat tgcttatgcg ttcttttgca gctatcgttc ttacaggaat
     5581 gtggggatac ccaggagcag cagcagcttc tcctttagct tggatcggtt ctgttgccgt
     5641 gttgctttac tcttatatgc gttcgatgaa acaattgaaa cacatgggtg aagaggaaca
     5701 tttcacatta gaacatgcag aagcaagata gccttgatta aaagaaatcg ttgcggctaa
     5761 aaatgaaaac ttttattgaa aatatcttct tcgtttaccg aaaacaggtt ttttagataa
     5821 caaaaaggct gtgacaaaaa atgtcacagc cttttttctt ttattctatt tttctttccg
     5881 tggactctac tttgaaataa tcgatatgtg catgctggta ttctaatacc gtgaaacgga
     5941 atgatgcaat ctcaatgatt gttcctgctt ttatttcttt atatcggcta gaagcaaagc
     6001 ccgcaagtgt agtaaaattc gtttcttcaa actctggaat ctctacatga aaataacgct
     6061 ggaaatcatc taatgttagt ttgccggaga tgatataaga gccatctgac tgttccgcta
     6121 tcaatgcttc gtccaaatct gtctcatctc ggatttcccc gacgatttct tctaaaatat
     6181 cttcaatcgt cactaagccg cttgtccctc cgtattcatc ttttaagata gcaatatgct
     6241 ttcccttttt tcgcatgatc gtcaataatt tttttatagg gatcgtttca gttgttacga
     6301 tcggctcttc aatcaactgt tctactgtca gctggtcatc tttataagat tgcttgatca
     6361 aatctggcaa ggtgacataa cctaaaacat tgtcttttga ttctaagata accggatagc
     6421 gagtatgtcc ttgttcaatc gaagctttta tcgcttcttt gacggtttct gaagcttcga
     6481 atacttgcat ggacgtacgg tctacttgta tatcttttgc caaggtatca tcaaattcaa
     6541 acacgttttc caaataatga tattcttctt tggtcaactc tcctttttca taagaattca
     6601 atgcgactaa tgtcagctct tcttgagaca atgtctcttc tccttcagat acgagacgca
     6661 cacctaatag cttccctagc cctgcagctg aatgattcaa tacccaaata aaaggaaaca
     6721 ttactttata aaaataatga agtggtttaa ctacgaacaa gacgaccttc tccgtattga
     6781 cgatactata gctcttagga agcagttcgc caataaccac atcgatatac gtaactaaaa
     6841 taaatcccag cgccacagag attgtactgc taatagccga actaaaaggt agtttaccga
     6901 tcactggttc tagtaaagcc gcgacagatc cttcaccgac ccacccgatg atcaaaccgg
     6961 ttagcgtaat tcctaattga ctagctgata aatagttatc taaatggtgt gtaacatgaa
     7021 gagctagctt ggcgttcttt acattttcct tttctagttg ttccaatctt gatcgtctga
     7081 ttttcactaa agcaaattca cttgctacaa aaaatgaagt aattgcaatc atcaaaaata
     7141 aaataatgaa attgataacc atattctccc gcctttctct ttttctattg tacccttttt
     7201 ctacaaaaag attgaaaata atgcgtattc atatttagga ataaaaaagg agatgcggca
     7261 tttttcagcc acatctcctt atcacttcaa aatcattgcg ttacttgttg ctaaacagct
     7321 ttttcatgac ctctgataaa cggtgttcaa gtagctgaca ttcgacatta gttcaggtca
     7381 aagcgctact ttcacaaccg ctctttcaac catgttttcc gagtatttcc aatgataagc
     7441 ggaacagttt catgttttac ttcgctgtac tctagcccaa accatgtttc tggcgaggta
     7501 gcgatttttt tgattgccag ttttgcctgc atgatttgac gttgccattt tcctagagtt
     7561 gtcacattgg aaactacttc atcaatcagg acaaattgga aatcgccaac ttctcgccct
     7621 ggtgtcagag agtatctttg tggctgtttt ggcaaacggc cttgtttcat caaatcatgg
     7681 atgacttggc gaacatatac gttgatttcc tgttggaccc tgaaacctaa gaacagattc
     7741 acttggacaa taaaatcagt gtccatcata tctacttgat attctttcgt atatggctca
     7801 tccgtcactt ccacatgaac aaaccaatag actcgtgctc ttttaggccg tttatctaaa
     7861 atcgaataga tgaactgtcg gccaacttta tcttcagcca tatcaggaac caagaagacc
     7921 acatttgtct gatagattgg taaagaagta tcatcacgta attctctaag ctgcgggata
     7981 taatctctca aagacacatc ctcggttgac gattcgcgaa taatgttccc ttgttcccaa
     8041 ataaacatca cgactaagat gatcaaacca atcagaacgg ctacaaaacc gcctcggaag
     8101 aatttgacaa cacttgagat aaagaaaacg acttctatcg caccgaagaa aaaggtaact
     8161 aaatatgcaa gccaacgaga atgcccattt tggataagat aaaagtaaag cagtgctgtt
     8221 gtcatcaaca tcgtcacagt gatcgataga ccgtaagcag cttccatatg atgagacgtt
     8281 cggaatgtga caaccactag agaacaggcg atccataaaa tcagattgac tgctgggata
     8341 tacatttgcc cgatactgtt cccaggatac atgatcttta accgaggcag cagtttcaac
     8401 ttgattgctt ctgaaactag cgtaaacgaa cctgtaatca atgcttgcga agcaatgact
     8461 gcagcgactg ttgcaaaagc aacgccgatc acgatccaac tttgaggcat catttggaag
     8521 aatggattca ggttcttgat ttgctgtgct tcagggtttt gataaacatt caacaaccac
     8581 gcagcctgcc caaaataatt gataaccaaa caaattttga cgtaaggcca gctcagacga
     8641 atatttcgtt tgccgacatg tccaagatcg gaataaagcg cctctgcacc tgtcgtagcc
     8701 aggaaaatat ttccaagaat gaacaagcct aatttgttat ctgcactaaa aagcagctgg
     8761 atagcataat aaggattcag tgcacggata actgtccagt cttgactgaa gttcattaat
     8821 cccattacgc ctaaaaaagt aaaccaagcg aacatgattg gtccgaatgc ttttccgaca
     8881 atatctgtac caaagcgttg gaccatgaat aaaacaaaaa taataactaa agtgataatg
     8941 acgatcacgt tctggttatt accgaaccgg tcaaaaaact gcggaattcc tcgcaagcct
     9001 tcaatcgcag tcgttaccgt cacagcaggg gtcaataccc catctgctag taaggcagct
     9061 cctccgatca ttgcaggaat gatcaaatat ttcccacctt ttcggacaag tgtgtagagt
     9121 gagaaaattc caccttcacc atggttatct gcattcaatg caatcacgac atatttgatt
     9181 gttgtcagta gagtcaatgt ccaaaaaatc aatgagactg atccgataac aaaatcagga
     9241 ttgattcctg acaatccgcc attatcttca acaatcgatt tcataacgta aagcggactt
     9301 gtcccgatgt ctccgtagac gactcccatc gctacaagca ggccagccat tgatatcttt
     9361 ttggtattgt gcgttgttgc cacgtttttc cctcatttct tgttatatgg atatccttta
     9421 ggtaagcttg aatgatagat gatattctta tccatgacac ccgctttcct aaattgcttc
     9481 taattatcca agtaacacac tgaagtgtca acttatttga ataaaattat tctttctttg
     9541 gacgttctct gatacgtctt gccacaaatg aataaagagc aaggcaaaaa attgcaccca
     9601 ataatgctgg tatcaaataa aaaccgccga gttccggtcc cagtggtcct agtaaaaatt
     9661 cgccgagcca actacctaaa aaaccgataa tgatatttcc agatacgcct cccgggactt
     9721 cctttcctaa aattgcgcca gctatcaaac ctaatatacc gccgataaat aacgaccata
     9781 aaaaattcag catctccttt ccctccttta tccatatttc tcacttttat tttacgcttt
     9841 attcagaagg actccaaaaa tatgcgccaa gaaactccag aaaaaaagaa gttgtaacaa
     9901 aagtgttcag cttatttccg tagaagctgc ttctggaaca ccgtgaatca gaggttgtga
     9961 aatcagcggt ttgacctgag tattagagaa acaaacggaa aaatagttcc tcatattttg
    10021 ccgttttttg agctaatatc gagggacagc tgattgaaca tcgtttattg gagaggttgt
    10081 aaaaaagctg ttctgcatca agtaataaga acagccaagt aaaaacagct cctaatgttt
    10141 ttaacttggc tggacttatt accgcagatg caagcttttg aacaccgttt attcgaaaaa
    10201 aaaggactgt gacacggctt ttgtcacagt cccctttttt cgaataatta ttgtccccct
    10261 gtcaccttca cgatcacaag tacattattc ctatgaatta aattattttt cttcattttt
    10321 cgttgaacca tcttcgttca acattgcttt tcttgacaga tttacgcgtc cttgtttatc
    10381 gatttcagtt actttcacaa ggatctcatc acctagttta acaacatctt cgactttatt
    10441 gacacgatcg tttgctaatt gggaaatatg gacaagtcca tcttttcctt tgatcaagtt
    10501 gacgaatgca ccgaattttt cgatacggac aactttccct agataaactt caccaacttt
    10561 gacttctttg gtcaaatctt cgatgatctt gatagctttt ttgatcattt ctgcatcagc
    10621 tgaagcaata cttacttttc catcttgatc gatatcgatt ttcacaccag tttcatcgat
    10681 gattccgttg atcgtatcgc cgcctttacc gataacatct ttgattttag caggttcgat
    10741 ctggatcatt tcgatttttg gtgcatattg gcttaattct tcacgtggag cagcaatcgt
    10801 tgaagtcaat tcttctaaga tttccatacg tgcttgtttt gcttgagtta atgcttcagt
    10861 taggatttgt tctgtgattc cttgaatctt gatatccatc tgtaaagcag tgataccatc
    10921 ttttgtaccg gcaactttaa agtccatatc gccaagatga tcttccagcc cttggatatc
    10981 agttaggatc gtatagtttt caccatcaga aacaagtccc atcgcaatac cggcgactgg
    11041 cgctttgatt ggtacacctg catccatcaa tgctaatgtg ccagcacaga tacttgcttg
    11101 ggaagaagaa ccatttgatt ccaatacttc tgctactaaa cggatcgtat aaggaaattc
    11161 ttcttctgaa gggattactt gtgctaacgc acgttcacct aatgcgccat gtccgatttc
    11221 ccgacgccct ggagagcctg cacgtcctgt agaaccaaca gaaaattgag ggaaattgta
    11281 gtggtggatg aatcgtttgc tgacttccac ccctaaacca tcaatgattt ggtgctctcc
    11341 tagaggtgcg agtgtacaag ctgataaagc ttgtgtttgt cctcgtgtga acaaacctga
    11401 tccatgtaca cgtggcaata agctgacctc tgatgacaat ggacggattt catccaattt
    11461 acgcccgtca ggacggatct tatcgatggt gatcaattca cgtacgacat ctttttcaag
    11521 atcttctgtg atttgtttaa cttctttcaa caagtgatct tcatcttcat gacctgcaaa
    11581 tttctcagca taagcttcgc ggatatcgat cttcacctgc tcgatattat cttcgcgagc
    11641 aagtttttct tcagtcatta ctgctgcttt cattgtagcg taagaagcat caaagatttc
    11701 ttttttcaat acttcatcaa cttgcagtaa agtcacttcc attttttctt tccctactgc
    11761 ttgaacgatt tcttcttgga aagcaactaa ctctttgata gcgtcaaaac caaacagcaa
    11821 tgcaccaagc atgtcttctt ctgaaacttc tttcgcgccg ctttcaacca tattgatggc
    11881 ttgtttcgtt ccggcaacag tcaattcgat atctgtttgt tctgcttgtt ctactgttgg
    11941 attcaagacg tactcgccat ttacacgacc aacttctacg cctgcgattg ggccgtcaaa
    12001 tgggatatct gagattgata gtgctaaaga agaacctagc attgctgcca tagctggcga
    12061 gcagtctgtt tctacactca tcacgatgtt cgttacttgg acttcattac ggaagccttc
    12121 tgcaaacatc gggcgaattg gacggtcgat caaacgggca gtcaatgttg cttccgtact
    12181 tggacggcct tctcgtttga tgaaacctcc agggattttc cctgctgcat acattttttc
    12241 ttcataattg atcgttaatg ggaaaaagtc tgtatctttt gcttctttag aggccacagc
    12301 tgcacttaag actactgtat ctccataacg gactaaaacg gctccgtttg cttgttttgc
    12361 tagctgaccg acttcgattt gtaagggacg gccgccccat gtcgttttga atacttgttt
    12421 ttctgacata acttctcctt ttccttctcg tgaaagcaag acgctactaa acaaatgaaa
    12481 actgccgaaa gccgtctttt gagcagcttt catttggtta gtaggagtcc atctagcttg
    12541 atcacggaat tttacttaat tgatatacga gtaaaaaaag tgagattcat gtgaatccca
    12601 ctctttttga ctaaaattaa cgacgcaagc ctaaacgttt gatcaattcg cggtaacgtt
    12661 gaacgtcagt tttacgtaag taagctaaca agttacggcg gtgaccaact tttttcatta
    12721 ggccgcggta tgaatgatgg tcttttttgt gcacgcgtgc atgttcattc aagtggttga
    12781 tttcttcagt taatacagcg atttgtactt ctggagaacc agtatcccct tcatggcgag
    12841 cgtattcgtt gatgatttca ttcttgcgtt cttttgaaat tgccatttct ttcacctctt
    12901 tcgattattc ccctgcgact gagtaaaacg ttggtgattc gcttaaccaa gtggcaggtc
    12961 atgtgcctag agcacacagc tatactttac ctgaaaccgg gttgaaaatc aagtagttaa
    13021 tcattaagaa aaggtagttt tcaaacaatc ttactactac ttttccattt ttgtggtaaa
    13081 ctataatgcg aaaatagact tgaaacacag tcttttaaga aaggggtaca tattccatga
    13141 ttacaatgga tgatatcatt cgtgaaggaa atccgacctt acgcgaagtt gcaaaagaag
    13201 tttctcttcc attaagcgaa gaagatatct ctttaggaaa agagatgctt gagttcttaa
    13261 aaaacagcca agatccaatc aaagctgaag aactacactt acgaggcggt gttggcttag
    13321 ctgctcctca attagatatt tctaaaagaa tcattgctgt tcacgtacca agtcctgacc
    13381 cagaggcaga tggaccttct ctaagtactg ttatgtataa tcctaaaatt ttgagccatt
    13441 ctgttcaaga tgcttgttta ggggaaggtg aaggctgttt atctgttgat cgagaagtac
    13501 caggatatgt tgttcgccat gccaaaatca ctgtgtctta ttatgatatg aatggtgaaa
    13561 aacacaagat tcgtttgaag aattatgaat cgatcgtcgt tcaacatgaa atcgaccata
    13621 tcaacggtgt gatgttctat gaccacatca acgatcaaaa tccatttgca ctaaaagaag
    13681 gcgtattggt gatcgagtag agaattggca ggttccttcg atactatgct acaagaaagc
    13741 tttataaaaa aggggagtgc tcaaaagctg cacttccctt tttt
//
LOCUS       DAYNVV010000067        13379 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.070, whole genome shotgun sequence.
ACCESSION   DAYNVV010000067 DAYNVV010000000
VERSION     DAYNVV010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13379
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.070"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..899)
                     /locus_tag="ACGXWR_002303"
     CDS             complement(<1..899)
                     /locus_tag="ACGXWR_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HFK0803828.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFS"
     regulatory      complement(923..967)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1182..2150
                     /locus_tag="ACGXWR_002304"
     CDS             1182..2150
                     /locus_tag="ACGXWR_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFK0803829.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            2263..2541
                     /locus_tag="ACGXWR_002305"
     CDS             2263..2541
                     /locus_tag="ACGXWR_002305"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFK0803830.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            2659..2895
                     /gene="secG"
                     /locus_tag="ACGXWR_002306"
     CDS             2659..2895
                     /gene="secG"
                     /locus_tag="ACGXWR_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HFK0803831.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            2998..3753
                     /locus_tag="ACGXWR_002307"
     CDS             2998..3753
                     /locus_tag="ACGXWR_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFK0803832.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            3756..6113
                     /gene="rnr"
                     /locus_tag="ACGXWR_002308"
     CDS             3756..6113
                     /gene="rnr"
                     /locus_tag="ACGXWR_002308"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HFK0803833.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKFGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            6135..6599
                     /gene="smpB"
                     /locus_tag="ACGXWR_002309"
     CDS             6135..6599
                     /gene="smpB"
                     /locus_tag="ACGXWR_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HFK0803834.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            6901..7620
                     /gene="atpB"
                     /locus_tag="ACGXWR_002310"
     CDS             6901..7620
                     /gene="atpB"
                     /locus_tag="ACGXWR_002310"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HFK0803835.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            7673..7888
                     /gene="atpE"
                     /locus_tag="ACGXWR_002311"
     CDS             7673..7888
                     /gene="atpE"
                     /locus_tag="ACGXWR_002311"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HFK0803836.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            7979..8503
                     /gene="atpF"
                     /locus_tag="ACGXWR_002312"
     CDS             7979..8503
                     /gene="atpF"
                     /locus_tag="ACGXWR_002312"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HFK0803837.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            8490..9032
                     /locus_tag="ACGXWR_002313"
     CDS             8490..9032
                     /locus_tag="ACGXWR_002313"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HFK0803838.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9055..10611
                     /gene="atpA"
                     /locus_tag="ACGXWR_002314"
     CDS             9055..10611
                     /gene="atpA"
                     /locus_tag="ACGXWR_002314"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HFK0803839.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            10625..11527
                     /locus_tag="ACGXWR_002315"
     CDS             10625..11527
                     /locus_tag="ACGXWR_002315"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HFK0803840.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            11550..12956
                     /gene="atpD"
                     /locus_tag="ACGXWR_002316"
     CDS             11550..12956
                     /gene="atpD"
                     /locus_tag="ACGXWR_002316"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HFK0803841.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            12970..>13379
                     /locus_tag="ACGXWR_002317"
     CDS             12970..>13379
                     /locus_tag="ACGXWR_002317"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HFK0803842.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVS"
BASE COUNT         4425 a         2403 c         2917 g         3634 t
ORIGIN      
        1 tcggaaaaaa gacgagtatc tacttttgtc ataattttac tgttagcagg tttctgccaa
       61 aattcataac gatcaaccaa tgtttgtcca cgacttattc cctgagtttc cacagcggtg
      121 aagcttttga aaccttcaca gatggccccc tcgatgaaat aagcaacagc taacggatca
      181 ttgatgacac atcctaaaat tctttcttgt ttccagtgga agtcaaaata aaaacgagtg
      241 atcgctttta aatactctcc ctcttcagga ttcatttgac agcagtattc gaggatagtc
      301 ggtgtcaaga cgatttctct tgtcacatct aacccaacca tttctatcgt ttgtttgaga
      361 ttctcgaata cataagaagc tgcttcagga tcacaccagt aattgtattc agcaactggc
      421 gaacagttac catggctttt gtaagttcca cccatcgaga caaaacgatc catatgtttc
      481 ccaatatttg ggttgacttt caaagcaaaa gcgatattgg tcaaaggacc caaagcaatg
      541 actgatgtat ttgtcttttc tttgaaataa tcagccaaaa aatcaacggc atggagaggt
      601 tctgcctgtt ttctcaagat catcgggaaa tttgtttccc ctaaaccatc cataccatga
      661 gtgtcttgtg cactgatgaa aggttgcttc aaaggttttt ccattccttg ataaacagga
      721 atgtctaaac gatcacagcg ttccaggcat ttcagcacat tctgcgtacc tatatctgca
      781 gggacattcc cacaaactac ggtaatagca actacttcga tatcagggga tttgacagct
      841 aatgataaag ctaaagtgtc gtcgatccct ggatcgcaat caataattac ttttcgcatt
      901 atttccaatc tcctttcttt agagatactt agttttttat tctgggaagt ttccgaacca
      961 gtccaagacg agcgtcttga ttataatgca cgaaattagt atactggctt ttattgcgaa
     1021 tgtaaatgct ctcttacaag taaatctatt gaggagaact ttaagtaaat gatacaatga
     1081 aaaagaaatg gaatttacgt gtgccgaaaa taaagaatcc tatggatcgg tacattggat
     1141 aatagataga ttatagtttg gcagaaagcg gcgggtgtac aatggttatt ttttatttca
     1201 ttcttattct gataattata gggatcagtt accattttct ttcttatttt tatgcaaaga
     1261 aattagtaag agcgggagta cagagaggat atgactggta tgaagacact ggtcatcgtt
     1321 tgatggaccc tgctgcagtc acgtcagtag aaaaaaaacg acaaaaatta gaagaagagt
     1381 gtgaaagctt ttgggagcag ggaacaccca aaacaatcaa aagttatgac gggttgaaac
     1441 tagctggtca gatgttcatc catccaaata agcagaataa atgggtcatt tgcgtacatg
     1501 attaccgaag cacagggaaa agagacatgt ctcatatagg taaaagatat gcagagaaag
     1561 gattcaacgt tcttgtacct gatttacgtg cgcacggaga aagtgaagga gaaatcatcg
     1621 gaatgggatg gctagatcgg ctagatttaa ttgcctggat ccaactcatc ttagatgaac
     1681 agccgaatgc gtccattatt ttacacggcg gatcaatggg agcttctacg atcatgatgg
     1741 caagtggtga aaaacttcca tcagcggtca aaggatttat tttagacagc ggatatgttt
     1801 ctgtttatgc agaattccga tatatgttaa gtaaaatcac tgtctttcct aaaaaaatgg
     1861 tcatgagata tgcgaatcat tatgcccaga aatacgccgg ttactcctta aagcaagcat
     1921 cagctacgag acagcttggc agcaaccatc tgcctttatt agtcatccat ggtgaaagag
     1981 atcattttgt ccctacagaa gcagcgtaca cgattcaaaa tgctacggca ggggataaag
     2041 cactgctgct tgttccagaa gcagaacact tggaagcatc gatgaaagat ccgaaaacct
     2101 attggacagt gattttttca tttattgaac aaagaataac gatggattaa ttttctcttc
     2161 ttttttgtaa gtaattcgag gataaataat tgtttataga tctggagact gctaaaataa
     2221 ggtaggaata aaaaaatatc agttatttga ggagtgcggc atatggaaat caaagaagaa
     2281 aaaaatcgtc ttgctttatt caatgatgag caacaagaga ttggagaaat gacatggtca
     2341 gatgcgggcc cagacatcat gatcattgac catacatttg tagatccagc atatcgtggt
     2401 caaaagttag ctgaaaagct agtgtatact ggagtagaat tagcaagacg agacgggaaa
     2461 aagatcattc ctttatgccc ttatgcaaaa aaagagtttg aaaagaaacc agaatatcaa
     2521 gacgtcttac gtcagtcata agaataacag ctgaaagttt tgaactttca gctgttattc
     2581 catttatata gagttgtcac ggacttttat ctatgataaa gttaaagaga cgatatcttt
     2641 tgggaaggag gctgcgatat gtataattta attttgggaa tcgtgatcgt tttatcgatt
     2701 gttatggtca ttgcgattat gatgcagcca agcaagcaaa atagtgcagc gagtgcattt
     2761 accggcggtg cggatcaact attcggcaaa caaaaagctc gcggctttga agctgtcatg
     2821 cagcgatcaa ctgcagttat gggagctatc tggatgatct tattatttgt cctagcatat
     2881 ttatcttcga agtagttgaa taagcctctc gcaaaacggc gggcggcttt ttttattgca
     2941 aagagaacgc ttaagaagaa gttatgaaag aaactatggt aaaatgaggc gaaagaggtg
     3001 agacgagtga gacaattacc aaaacccctt tatgcaaaac atggaaagcg agcggttttg
     3061 ctgcttcacg cttactcagg aagtccaaac gatgttcgaa tgctcgcacg atttttggaa
     3121 aaagcagatt atacagttta tgcgccgctt tttaaaggac acggaacaat ggagccatat
     3181 gatatcttgc aagaaaaagc agaaagctgg tgggcagaca ctaaaaaagc catccatttt
     3241 ttacagtctg agcagttttc tgatattgcc gtattaggat tatcaatggg cggcatcttt
     3301 gctgtacgag cactagaaga agaatcagtg attggcggcg gttttttctg ttcgcctttg
     3361 tctcctgtaa aaacaaacgt gcctgaaaac tttgaaaaat acgtacgtca agtgctgaag
     3421 acagcaggta aatcagagaa agaaatcaat gaaaaagcag ttgcttaccg ctcgttagct
     3481 gaacaacaat taatggatat acaagatcag gcagcaatcg tagaaagtag gttgtcagat
     3541 atccaacagc cgatattttt agctcaagct gggaaagatg aaatgatcga ccctaatggc
     3601 gtatttgaaa ctgcacgcaa gttgagccgt cagcgagtga cacttcaatg gtatcctgaa
     3661 agtggtcatg tgattacagt tggtacagca agacgcgaat tagaaaaaga cgtcttggaa
     3721 tttttagaaa aattaccttg gaatgaggaa taaatatgac aaaagaaacg ataaaagaga
     3781 aaattctctt tttcatggaa agcagtcgca aacgcagttt ttctatggaa gaaatcgctg
     3841 aaggtttagg gttccaaaaa agcgatgatt ttaaattact agtacaaacg attgctcaaa
     3901 tggaaagaga acagagtata gttttcaata aaaaaggaaa agtgaaactt cctttaaaac
     3961 caatcttgat cgaaggaaca tttcgagcaa atgaacgagg atttggattt gtaacgattg
     4021 atcccgaaga agatgacatc tatatcccaa aagaagcgac tggttttgca atggatggag
     4081 acaccgtagc aatcgatatc atgaagcgag caaatacaga tatggatcgc ggagcagagg
     4141 ggaaagtagt cgagattcga gaccgggcga ctactcagtt agcaggggaa ttcgttgctt
     4201 attcagaaga agaaatacaa gaaacagatc tttacggcgt tgttatcccg aaagatagaa
     4261 agctcaacca atttaaagta tatgcagcag cagagggagt tcgtccagtt gacggaagta
     4321 ttgtgctgat cgaactgacc cattaccctg aaaaagggta tgcgactagt ttagaaggga
     4381 taatcaagca agtgattggt cataagaatg accctggcat ggatatcctc tcaattgtcg
     4441 tggctaatgg tatccctacg aaatttcctg atgatgtatt gtctgaagca gatgaagttc
     4501 cagatcaaat cagcgaaaag gatataactg gacgtagaga tttaagaaat cagctcattg
     4561 ttacgattga tggagaagat gcaaaagatc tagatgatgc agttacggtt aaaaaattag
     4621 ataacggtaa ttattttctt ggagtacaca ttgcagatgt ttcttactat gtgacacaag
     4681 gcagtcaatt ggacagagaa gcatatgaaa gagggacaag tgtatatttg actgatcgag
     4741 tgattccgat gatcccgcaa cgtttatcga atggtatctg ttcactgaat ccccatgttc
     4801 caaggctgac catgagttgc gaaatggaga ttgatccaaa tggacaagta gtctctcatg
     4861 atattttccc aagtgtgatc caaacaacag aacggatgac ctacacagct gtcaatcaaa
     4921 tcttagaaga tcaagacgaa gaaacgatgc aacgctatgc tcagctcgta cctatgttcc
     4981 aagaaatggg tgaattgcat cgaatccttg aaacgatgcg aatcaaacgt ggcgcgattt
     5041 cttttgagga tcgcgaagcg aaaatccttg ttgatgctga aggacaccca aatgacatcc
     5101 agctaagaag cagaggaatt ggtgaacgct tgatcgaatc tttcatgctt gcggccaatg
     5161 aaacggtagc tgaacattat aataaattaa atctgccgtt tatttaccga atccatgaac
     5221 agccaaaaga agaaaaaatg cagcgcttct ttgattttgc ttcagctttg ggcattctgg
     5281 tccgaggaac gaaaggaacg atcacaccaa aagatttaca gcatgtgatc gaaggagtag
     5341 aagacaaacc agaagctgca gttatcaata ctatgttgct aagaagcatg caacaagcac
     5401 gctattcaga agacaatttt gggcattatg gcttagcggc agattactac acacacttta
     5461 catctcctat tcgacgctat cccgatctaa tcgtccatcg tctgatccgt tcttacagtg
     5521 aagataaaag tgaaagcaat caaagttcgt gggctgcgga acttcctgaa attgcagatc
     5581 atagttctaa gatggaacgt cgtgcagtag aaacagaacg tgaagtagat tccatgaaga
     5641 aagcagaatt catgatggac aaagtgggag aagaattcga tgggatcatc agctctgttg
     5701 tgaaattcgg cctgtttatc gaactgccga atacagtaga aggattgatc catatcaatg
     5761 aattgaaaca ggactacttc cattttgttg aaaatcattt agctcttgta ggtgaaagaa
     5821 ctggtctgac ttttaaaatc ggacaaaaag tgcgcgtaaa agtagtcaaa gctgatccag
     5881 atgaacgagc agtggatttt gaactcgttt ccgcagaaga ggtcactgcg ttggaacgtc
     5941 caaaagcacg caatggaaaa tttggaaaac gagaaggaaa acaagcaggc aaacgctcag
     6001 aaaaaaatgg caagaagaac aaacgatata gtgatagtaa gcaaacgttc ggtaagaaaa
     6061 aagggaaaaa gccattttac aaagatgtca aaaagaagaa aaagaaaaaa taaaatgagt
     6121 tggaggaaac agctatgcca aaaggcgagg gaaaactaat tgcacaaaac aagaaagctc
     6181 gccatgatta ttcgatcatc gacacgatgg aagcagggat ggtcttgcaa ggaacggaga
     6241 tcaagtcgat acgaaacagc cggatcaatc tgaaagatgg atttattcgc gtccgcaacg
     6301 gggaagcttt cttgcataat gttcatatca gtccttatga acaaggaaat atttttaatc
     6361 atgatccgtt gcgcacgaga aagttattat tacacaagaa acaaatcgtt cgtcttgaaa
     6421 acgaattgaa aaacactgga atcactgttg ttcctttaaa agtctatatt cgtaacggct
     6481 atgccaaggt attgattggt ctggcaaaag ggaaaaaatc gtatgataaa cgggaagatt
     6541 tgaaacgaaa agatatcgat cgacaaattg atcgaacatt aaaaaatttc tctagataat
     6601 ttcattatcc tttttcgcat attcggtgct tttgctttta cttaatgata aaatttgtta
     6661 gcatttaatc tgataaaaca tgattatcac aggttttttc ttagatcagg agcaccgtgc
     6721 atggggaaaa attcgcttcg tttttgactg aaataaaaaa gtgtctaatt ttcatgaaaa
     6781 tgttttgaat tttctgtttc atggtggtat gataccgtgt ggttagaaac cgattggaaa
     6841 aaaccagata cgcacatgaa ttgattttat gtgaatttcg gggaaaagag gtgaaatgga
     6901 ttggatgaac gctcgctaac gtttcacatt ggaccaattt ggtttgatgg tacagtttgt
     6961 ataatggtgt tactgacctg tttgattgtt ttcttcttag cttacttttt tacaagaaat
     7021 cttaagttga aaccaacagg caaacaaaat gcgatagaat gggtcattga ttttagtcga
     7081 ggaatcgtaa cagataatct gcctagaaaa gaattgagca atttccattt gttggcattt
     7141 acattgtttt tatttgtttt tgttgcaaac aacataggtt tagtaacaaa aatcgtctta
     7201 cctaacgaaa caacactttg gaaaagcccg acagcagacc cgtttgttac tttaactttg
     7261 gcatttataa tgatcttact tactcactta ttcggggtga aaaagttagg cttcaaagga
     7321 tatttcgtaa attcgttctt gaaaccctat agttttatgt ttccgatgaa actgattgaa
     7381 gaatttacaa atttattaac acttgcttta cgtctttatg ggaatattta tgcgggggaa
     7441 gttttgctaa ccttgattgc aaaaatgatg acaagcttag gctggttctc attaccatta
     7501 gcaattccat tagagatggt ctggatcgcg ttctccttgt ttattgggag catccaagca
     7561 tttgtctttg tcactttgtc aatggtttat atgagccata agattgaagt agaagaataa
     7621 tactcggtta aaaaacaaac tactatttat ctattttagg aggaaaacaa ttatgaatta
     7681 tatcgcagca gcaatcgcaa tcatgggagc agcaatcgga gccggttatg gtaacggtca
     7741 agttatctct aaaacaatcg aatcaatggc tcgccaacct gaaatgtctg gtcaattccg
     7801 tacaacaatg tttatcgggg tagctctagt tgaagctgtt cctatcttag gggtagttat
     7861 cgccttgatt ctagtttttg ccgtttaatt gaatcagtat taaggcagaa acaacatcgt
     7921 ttgttactgc ttttttacat ggaaactaga aatactccaa agaaaggaag gctcgcctat
     7981 gctgaatcaa ttggcaattg cagaagttgg caatgcgatg ttaggtaata tcatcgttgt
     8041 cagcggctca tttttgatac tactggctct cttgaagcac tttgcttggg gaccaatcag
     8101 cgatattttg aaaaaacgtg aagacaagat cgccaatgat ttagattctg cagaacaatc
     8161 tcgcatcaac tcagcgaaaa tggaacaaga acgcgaacaa caattgttag cctctcgttc
     8221 tgatgcagct gatatcatca aaaatgcgaa agaaagtgga gaattaagcc gccaaaatat
     8281 tttgaaggat gctcaagaag aagcagctcg tctaaaaagc aaagcccaag ctgatatcac
     8341 tgtagaacgt gattcagcgc tgaactctgt aaaagacgac gttgcagaac tctctcttca
     8401 aatcgcggaa aaaatcttga acaaagaatt atctccagaa atgcatgaat cattaatcaa
     8461 tcaatacatt gaaggtctag gttcttcaaa tgaaactaga taaatataca gtaggaagac
     8521 gttacgggaa agctttattt gaactggcga tcgattcaaa tcaagcagaa gaaatctatc
     8581 aagatctcgt aagtttacgt caaatctatg aacaagtacc tggattaggg aatatgttaa
     8641 gtgatgttcg tctagaacct catgaaaaac gagaaatcat ggacaagctt gtcagcggtt
     8701 atgatgggat cgttaaaaac tttttagaag ttgtttatga gtataaccga atggatgacc
     8761 ttttgttcat gatcgaagaa tatgaacgtc gatatgatga acatcaaggg ttactattgg
     8821 gaagtgtcac aacagcagtc ccactttcag acgaacaacg aatacaatta gaaaagaatg
     8881 ttgcaaaaac aatggactat caatcagttg aattaaaaca aatcgttgat tcttctatta
     8941 ttggtggcgc gattgttgaa gccaaccatc gagtaatcga cggaagcatt cgcacgcaat
     9001 tagaaaaaat gcgtaatcaa ttaaacagat agtacaaaga ggtaggtgaa tcgaatggcc
     9061 atcaaagcag aagaaattag tgccttgatt aaagaacaaa ttgaaaatta tcaaaacgtg
     9121 ctttcagtcg aagaaatcgg taccgtaact tatgtaggtg acgggatcgc tcgtgcacat
     9181 ggtttagaaa acgcgatgag tggtgagttg cttgaatttt caaacggctc atacggaatg
     9241 gcgcaaaact tagagtcaaa tgatgtaggt atcattatcc ttggcgattt cgagtccatt
     9301 cgtgaaggag ataaagtaaa acgaacaggt aagatcatgg aagttccagt tggagaggcc
     9361 ttgatcggtc gggtagtcaa tccgctaggt caaccaatcg acggactagg tgaaatcgtt
     9421 actgacaaag ctcgtccagt agaagcgatg gcaccaggtg ttatgcaacg taaatctgtt
     9481 aacgaaccaa tgcaaacagg gctaaaagcg atcgacgccc ttgtgccaat cggacgcgga
     9541 caacgtgaat tagtcatcgg tgaccgtaaa acagggaaaa cttctattgc gatcgatacg
     9601 atcatcaacc aaaaaggtca agatatgatc tgtatctatg tagcaatcgg acaaaaagat
     9661 tctacagttc gtacacaagt tgaaacattg aaaaaatatg gcgcaatgga ttacacaatc
     9721 gttgtgaatg ccggtgcgtc tcaaccagca ccattgcttt atatcgcacc atatgctggt
     9781 actgcaatgg gtgaagaatt catgtacaac ggtaaacatg tattgatcat ttttgatgat
     9841 ctttcaaaac aagctgttgc ttatcgtgaa ctttccttgc tgcttcgccg tccaccaggt
     9901 cgtgaagctt atccagggga tgttttctac ttacactcac gcttattgga acgtgcagca
     9961 aaattaagtg atgatttagg tggcggttca atgactgcct taccatttgt tgaaacacaa
    10021 gctggagata tctctgctta tatcccaaca aacgttattt cgatcactga tggacaaatc
    10081 ttcttagaaa gcgacttgtt ctacgcaggt actcgtccag cggttgatgc cggactatct
    10141 gtatctcgtg tagggggttc tgcgcaaatc aaagcaatga aaaaagttgc tgggacttta
    10201 cgtctagact tagcaagtta ccgtgaatta gaagcattta cacaattcgg ttctgacttg
    10261 gatgcagcaa cacaagcaaa actaaatcgt ggacgccgta cagtagaaat cttgaaacaa
    10321 aaattgcatg caccgctagc tgttgaaaaa caagtagtga ttttgtatgc tttgacacat
    10381 ggattcttag atagtatccc tgtagacagt attttagact tcgaacatga attattcgaa
    10441 tatctggata ccaatcattc agatatcttt gaaacaatcc gtacaacaaa agatcttcca
    10501 gaagaagaag cgttgaacag tgcgattcag gaatataaag acatgttctt agctacaaaa
    10561 ggaaataatt cctctacaga agataaattg aaatccattc aaaatgcata gtgaggtgag
    10621 atgaatgggt gcttcattaa atgaaatcaa gacacgtatc gcttcaacga aaaaaacgag
    10681 ccaaatcacg cgggcaatgc agatggtgtc tgcttctaag ttgacaaaat ctgaagcttc
    10741 ttcacagaag tttcaggttt atgcaacaaa agtaagagaa atcgttacgc atttgactgc
    10801 tactcagtta aatgatattg cctcagaaaa tcctagaggg gatatcaatt acaacagcat
    10861 gttgctcagc cgtcctgtta agaaaacggg ttatatcgtc atcactgcag atggcggttt
    10921 agtcggtgga tataacagct cgatattgaa acaaacgatg tctattttag aagaagacca
    10981 ccaatcaccc gatgattacg tgatgatcgc aattggcgga actggtgcag acttctttaa
    11041 agcacgcggt atcaatctag catatgagct gcgcaatcta tctgatcagc caagctttga
    11101 tgaagtccgc aaaatcgtaa atatggcaac aactatgtac caaaacgaag tattcgatga
    11161 attatacgta tgttataacc atcatatcaa ttcgctaact agtcagtttc gtgtagaaaa
    11221 aatgctgcca atctcagact tagatccaga agaagcaact actttcgaac aagaatatat
    11281 ttttgaacct tcaaaagaag aaatcttgtc tcagttattg cctcagtatg ctgaaagttt
    11341 gatctacggt gcgatcgttg acgccaaaac agcagaacat gctgctggta tgacagcaat
    11401 gaaaacagca actgataatg ctgctaatat cattgatgag ctgacggttt cttacaaccg
    11461 tgcaagacaa ggggctatta cccaagaaat taccgaaatt gttgccggag cttcggcact
    11521 agaatagtat tgagattgga ggaaaaaaga tgagttcagg caagattgtt caagtaatcg
    11581 gtcccgttgt cgacgtggaa ttttctttag accaatcctt accagatatc aacaacgcat
    11641 tagttgttta taaaaatgac gaaaataaat caaaagttgt tcttgaagca gcgttagaat
    11701 taggggacgg agtgatccgg accattgcga tggaatcaac agatggttta caaagaggaa
    11761 tggaagtcat tgatacaggc aaagcaatct ctgttcctgt aggtaaagaa acattaggtc
    11821 gcgtattcaa cgtactagga gatacgatcg atttagaaac acctttccca gaagatgcgg
    11881 aaagaagcga aattcataaa aaagcaccag cctttgacga attaagtaca agtacagaaa
    11941 ttttggaaac agggatcaaa gttatcgatt tgcttgcccc atatttaaaa ggtgggaaag
    12001 tcggactatt cggtggtgcc ggtgttggta aaaccgtact gatccaagaa ctgatccata
    12061 atatcgccca agaacatggt ggtatttctg tatttaccgg tgtaggtgaa cgtactcgtg
    12121 aaggtaatga cttgtattat gaaatgaaag attcaggagt tatcgaaaaa acagccatgg
    12181 tgttcggaca aatgaacgaa ccaccaggtg cacgtatgcg tgttgctttg actggtttga
    12241 cgattgcgga atatttccgt gatgtagaag gtcaagatgt actgttgttt atcgacaaca
    12301 ttttccgttt cactcaagct ggatctgaag tatcagcctt gttaggacgg atgccttctg
    12361 cggttggtta tcaaccaaca ttggcaacag aaatgggtca attgcaagaa cgtatcacat
    12421 ctacgaaaaa aggttcgatc acatcgatcc aagcaatcta tgtgccagcc gatgactaca
    12481 ctgacccggc gccggcaaca gcattcgccc atttggatgc gacaaccaac ttggaacgta
    12541 aattaacaga acaagggatt tatccagcgg tagatccatt ggcttcttct tcaagtgctt
    12601 tagcacctga aatcgtggga gaagaacatt ataaagtagc aacagaagtc caacacgtat
    12661 tgcaacgata tcgtgaatta caagatatca ttgctatctt aggtatggat gaattatccg
    12721 atcaagaaaa agtgttagtt tctcgtgccc gcagagtcca attcttcttg tcacaaaact
    12781 ttaacgtggc tgaacaattt actggtcttc caggttcata tgtccctgta gaagaaacag
    12841 tgaaaggatt ccgcgaaatc ttggaaggca aatacgatga tcttcctgaa gaagctttcc
    12901 gaagtgttgg ccgaatcgaa gacgtcgtag aaaaagcgaa aacactaggc tactagaaag
    12961 gggtgcccca tggatcaata tttaacagta aatgtggtaa ctcctgccgg tttggtctat
    13021 gatcaccatg cagctatcgt cgttgcacgt acgacagctg gtgagcttgg gattttgcct
    13081 aaacatgcac caatcatcgt tccattgacg attgatgaag ttcgtgtaaa acgaacagat
    13141 tcagataccc acgtcgattg gatcgctgtt aatggcggaa tcatggaagt tcgtgataat
    13201 gttgtttcaa tcgttgctga tagtgcggaa cgtgaacgtg atatcgatgt atctcgtgcg
    13261 gaacgtgcaa aacaacgcgc agaacgccaa atcgaagaag caaaagcaaa acaagatacg
    13321 aacgaattga aacgggcaac tgttgcgttg caccgagcaa tcaatcgtat caaagtatc
//
LOCUS       DAYNVV010000068        13147 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.071, whole genome shotgun sequence.
ACCESSION   DAYNVV010000068 DAYNVV010000000
VERSION     DAYNVV010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13147
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.071"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(78..150)
                     /locus_tag="ACGXWR_002318"
     tRNA            complement(78..150)
                     /locus_tag="ACGXWR_002318"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(115..117),aa:Lys,seq:ctt)
     gene            531..1100
                     /locus_tag="ACGXWR_002319"
     CDS             531..1100
                     /locus_tag="ACGXWR_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HFK0803843.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1087..1947
                     /locus_tag="ACGXWR_002320"
     CDS             1087..1947
                     /locus_tag="ACGXWR_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFK0803844.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2137..2841
                     /gene="yycF"
                     /locus_tag="ACGXWR_002321"
     CDS             2137..2841
                     /gene="yycF"
                     /locus_tag="ACGXWR_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HFK0803845.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2846..4681
                     /gene="walK"
                     /locus_tag="ACGXWR_002322"
     CDS             2846..4681
                     /gene="walK"
                     /locus_tag="ACGXWR_002322"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HFK0803846.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4678..5994
                     /gene="yycH"
                     /locus_tag="ACGXWR_002323"
     CDS             4678..5994
                     /gene="yycH"
                     /locus_tag="ACGXWR_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system activity regulator YycH"
                     /protein_id="HFK0803847.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5995..6864
                     /locus_tag="ACGXWR_002324"
     CDS             5995..6864
                     /locus_tag="ACGXWR_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HFK0803848.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6919..7728
                     /locus_tag="ACGXWR_002325"
     CDS             6919..7728
                     /locus_tag="ACGXWR_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFK0803849.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7831..8460)
                     /locus_tag="ACGXWR_002326"
     CDS             complement(7831..8460)
                     /locus_tag="ACGXWR_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFK0803850.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8630..9922
                     /locus_tag="ACGXWR_002327"
     CDS             8630..9922
                     /locus_tag="ACGXWR_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFK0803851.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9998..10660)
                     /locus_tag="ACGXWR_002328"
     CDS             complement(9998..10660)
                     /locus_tag="ACGXWR_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFK0803852.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10885..11169
                     /gene="groES"
                     /locus_tag="ACGXWR_002329"
     CDS             10885..11169
                     /gene="groES"
                     /locus_tag="ACGXWR_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HFK0803853.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11220..12845
                     /gene="groL"
                     /locus_tag="ACGXWR_002330"
     CDS             11220..12845
                     /gene="groL"
                     /locus_tag="ACGXWR_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HFK0803854.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4370 a         2265 c         2833 g         3679 t
ORIGIN      
        1 ataaaaaaag aacagcgtaa atgttttcga aatgctttcg caccaacatt tacctgttcc
       61 gtgggtttgg cacccaatgg gccgtgaggg gctcgaaccc gcgacccgct gattaagagt
      121 cagctgctct accaactgag ctaacggccc gtacaaaaag tacttaataa tagtagcact
      181 aagaatttta aaatgcaaga ctacatttaa agaaaatcag aaaaatcttt acttccttat
      241 aggaaatcat tcatagatta ttcacatttg ctcgctatta tataagcata ccaacaaaca
      301 aagttcttgc aagagaacaa accctaacac ttttttcatt ttttactcct ttcccgccgt
      361 ctccccggcg ggtctcctgt tcttaacgat aaaagacaag aaggcttagc cttcttgttt
      421 tttgttttca tggaatcccg ctaatcaaat cacctagtta aagcaactag attgaatgtt
      481 tatcataagt ctgatatcat gtttatgaaa tgaaaaaagg agcggttatg atggaaaaaa
      541 tgcgtcagca attaatggag tgggggaagg aactagaaac attccgtctg cctcactggg
      601 aagaactccc tgacttagaa ctttatatgg accaagtcag aacgttagtt gatcgttatc
      661 tttcacctgt gatacaagga gaaaagcatc cattgcttac ctcttctatg gtaaacaatt
      721 acgttaaact aggtttgata ccagcaccag ttaaaaaaag atataacaaa gaacacgtag
      781 catttttact tgcaatcact acgttgaaac aagtattgac tattcctgaa atcaaagaag
      841 ggatattgtt ccaaggaaaa acagtaggaa ttcgtgaagc ctataatcta ttttgcgatg
      901 aacaagaagc agctgtgtgg atggtcagcc aattagcaca aggtaaatct catccgcaaa
      961 aattcgacca ggcaacccct gtagaatata ttgctgtaag agcggcaact ttatcgtttg
     1021 caatgaaact tcttgcggaa aaaacgattg ttctagaaac cgaatattta aaagaggaga
     1081 aaacaaatga aaaacaataa aatcgcaatt ttagtagatt caggtacgga tgtgccagaa
     1141 gaattgataa aaaaatacga gatgtatatg atcccattga aaattattta taaagatcag
     1201 gtatatacag ataaaattga cattacctct gaagagatct atcaacgttt gccagaggaa
     1261 atccctggta catctttgcc ggatggtgag tcgatcacag aaatctttga gcaaatcaaa
     1321 aaagacggtt atgaaaaggt acttgcggta acaatttcca gtggattgag cgggacatat
     1381 aatgtggttc gtttaattgc acaacagcaa gaagaattgg aagcatatgt actagatacg
     1441 aaaaatattg gtattggtgc aggtttttct gcgatccaag cagcaaaatg gctggaagaa
     1501 ggagtagaat gggatcaact gatcagtaat ctgaatgagt tagtcgaaag aacaaaagtt
     1561 ttctttaatg ttgcgacatt ggaatatctt caaaaaggtg gacggatcgg tttagttgct
     1621 tctattgtag gaaccgcttt aaagcttaac ccaatcatct catgtaatga agaagggatt
     1681 tattacacag taggaaaagc taggggacgt aaaaaaagtt tggataaaac ggttgcttac
     1741 gtcaaagaaa aaatcggtaa tgcaaaggtc ttcaacttag ctgttgccca tggggatgcg
     1801 aaagaagaag caattgaaat ggaagcgaga cttaaaagag agttcccaca agcaaaccaa
     1861 atctactttg gccagatttc tccggcatta gtagtccaca ctggtccggg attattgggt
     1921 gtcggtgtac aagttttaga aggataaatc aaaaaaagga aacactgagg tgaaaatcag
     1981 tgttttcctt ttttattgaa gttagaacaa aaaataataa agtattttgc actttcattt
     2041 taattttctc ttttgtttta taggcaaaga tgaaacaaaa gcagaaatac ggtataatga
     2101 gaaggtatga caataatata taagaggtgg ctctttatga aaaaagtttt agttgtcgat
     2161 gatgagaagc cgatttcgga tatcgtcaaa ttcaatttag ccaaagaagg ctatgatgtt
     2221 tatactgcat atgatgggga agaagccttg gaaaaagttg ctgaggtaga acctgatttg
     2281 attttacttg atttgatgct acctaaaatg gacggcttag aagttgctcg tgaggtacgc
     2341 aaaacttatg atatgccgat cattatggta acagccaaag attctgaaat tgataaagtc
     2401 ctaggcttag agttaggcgc cgatgattac gtgaccaagc cattttccaa ccgagaatta
     2461 gttgcacgtg tcaaagcaaa tcttcgtcgc ggtgccacgg ctgcgaagga accagaagag
     2521 gcagcacctg cggaattgac gattggtgat ttgacgatcc atccagaagc ttacatggtg
     2581 acgaaacgag gagaaacaat cgagttaaca catcgtgaat tcgaactact cttttacttg
     2641 gcgaagcacc ttggacaagt gatgacaaga gaacatttat tacaaacggt ttggggttat
     2701 gattattttg gagatgtacg aacagtggat gtaactgtac gtcgtttgcg tgaaaagatc
     2761 gaagataatc caagccatcc aaattattta gtgacacgtc gtggtgtcgg ttactatttg
     2821 cgtaacccag aacaggagta attggatgaa aagaaaagtc cgcttttttc gatcagtcaa
     2881 ttttaagatc gctattacct ttattctgat tttattgatc tcgatcgaaa ttattggtgc
     2941 ctactttata cgtggtttag aacgttccac gatcaataca tttattaaag atatgaatca
     3001 aacggtggaa tcattagcaa caacaatcag cccggaattg aatcgaaaag ataatgcaga
     3061 tgatgaagag gtaaatgcga atatcaaaag atttattgaa aacagtgcga ctagcgatat
     3121 catcgaaata cgggtcgttg acgaaaaagg gatcatccga ggaacaaccg atgtcaatga
     3181 acaaagcgct gtgggaaaga aaaatgatta tgttgatatc aatgatttca cgactaaacg
     3241 ttatgttgct ttagataacg acgataaacg ggtgaatatc aatgttcaac cgatcctgtc
     3301 cccgaccggc gatgccgtta tcggggctct ttacgtcaaa agtaatatcg aacaaaaata
     3361 ttcggaaatc aataacacag cagtcatttt ctttactgcc tcactaattg cggcatttat
     3421 ttcaatgatc gtatctgttt tagttgctcg ttcgattaca cagccgatcg gtgaaatgag
     3481 agaacaagcc attcgaatcg ctagaggaga ctacagtcgg aaagtcaaag tgcatggaca
     3541 agatgaactt ggacagctgg ctgatacctt caatcagtta gctgaacgta ttgaagaagc
     3601 tcaagataca atggaagctg aacgcaatcg tttggatagc gtgctatccc atatgacaga
     3661 cggcgtcatt gcgacagatc gcaggggtaa agtcattacg atcaatgata tggctgtttc
     3721 cttgctagat atcaaaaacg aggaagcaat cggacaatcg attttgacac ttttagatat
     3781 cgaagaagaa tatacgttgc ggaaattatt agaagatcca aacgaaatgg tacttgaccg
     3841 ttcaaccagt acattggaaa gtgatcagat gatcttgcga gtagactttt ctatgatccg
     3901 tcgcgaatca ggttttatca gcggattagt agctgtcttg catgatgtga cagaacaaga
     3961 aaaaacagaa cgggaacgtc gtgaattcgt ctctaatgtt tcccatgaac ttcgtacacc
     4021 gttgacaagt atgcgtagtt atatcgaagc attgagcgaa ggtgcgtgga aagacgagga
     4081 agtagcacca aattttttga aggtaacgct agatgaaaca gaccgaatga ttcgaatgat
     4141 caatgacctc ttaaatctat ctcgcatgga tacaggtaat acccagcttc aattagaata
     4201 tgtcaatttc aacgagttag tgaattttgt tcttgaccgg tttgatatga tggtgggaaa
     4261 tcaggaaaaa aattataaga tccgtcgtga atttacgcaa agagatcttt gggtcgaagt
     4321 agatacagat aaaatcatcc aagtagtcga taatatcatg aataacgcga tcaagtattc
     4381 accagatggg ggaacgatta cttgtcgctt attagaaacg cataataacg tggttttaag
     4441 tatcaccgat caaggattgg ggattcctaa aaaagatctg aaccgagtgt tcgagcggtt
     4501 ctatcgagta gataaagcac gtgcaagagc acaaggtggg acaggacttg gattagctat
     4561 ttctagagaa gtgattaagg cgcatcgagg cgctatttgg gcagagagca aggaaggaaa
     4621 agggtcgact ttttatatct cgctgccata tgaaccttat gaggaggaat ggtgggaatg
     4681 agaatctctg aaaaagtcgt tcgtatagga ctcattttga tggttgcgtt aagcatatac
     4741 ttctcttatg caatctggct gagcccagca ggaaaaagtt caatcaacgt agatgagaca
     4801 aacactcaaa tgatcgagtc tcaaagcaat cgaaaaactt ccgaagtctt tcttccgctt
     4861 catgttacat ggcaccattc gggaatgatc caagaaacca acagtgaaaa tctcgtgtac
     4921 cgattgcaat tgatcatcga taaagcaaga tttggaaagc tttctgaagt agtttcagga
     4981 gacaaatcac agtttgaaca ggtgaaaaat ctgaactctg gttttgagtt ggcctataat
     5041 gcgccttttt tgctaagaga atacaaggaa gcatttgatt tagatttaga tgtgtcgaac
     5101 ttggcaaaag aaagcgaaaa tatgtatttt actagaatac aattcgatca aggaaataaa
     5161 aaaatccgat ttttgaatta ttcgaaccat ctcgtatatg aagcaaatat ttcgttgaat
     5221 tggacagata tcaataaaga attaacagca aaagacacaa aatggacaga aatgacaaca
     5281 gaaccatcga cgatcgacac gcaatatgct acgaaacatt cgatcaaact gaaaaagtat
     5341 agttatatcc tgtcacagca accctataca ctttttagaa atgctttttt ccagaaacca
     5401 gatagcgtga aaaataatga tgaaagcaat gaattgattt tttacggtgg gaatgaaaca
     5461 atgtctatcc attcggaaac gcaagtagtt gattttcgtg gagagctgcc agagaaaaaa
     5521 gaaaatgcta gtgtattttc tgaaagtttc ccctatatta gcaaattagg cagttcttta
     5581 gggaacctca gatattttga ccgcagtgac aatacgatcg attatcggat attcgtggaa
     5641 ggcttcccgg tttttgggac agacagcaga ggacagattg gtgtggaagt tggcggtgaa
     5701 acgaatggtt ctgtgcaagt gaatatccaa accagtttga atacgattca agtgccgata
     5761 ccttcagacg aagaagtaga acttgcaagt acgaatgaaa tcatccagca gttaaaagct
     5821 aagggagcag atagcaacaa gattggttca gtgatcgttg gctatacatg gcaaaatgtc
     5881 aaagaaacga atcgtgtcgt tgatctctta cctgaatggt atgtgaaata taaagataac
     5941 tggtattcag ctaacgacct tctggaaaaa ttacctggat tggaggcgaa ttaattggat
     6001 ttcaaaaaaa tcgaatggat atttttcgtc gcttttttag ggttgaatgt gtttttattc
     6061 agcagttatc atgacgcggt ataccaagaa aacaatgtca ttcgctctaa tcagactgaa
     6121 tcaatccaac aacgtctggc tagcgacgat atcacttaca cggggaagat ttcgtctgag
     6181 aacaagcaag gctattatct tagcgcggag cagaccaatc ttagcacttc attagcgaat
     6241 tatcgcaagg ctggtaaaag cggcttgctg gcaagtggtg tgtttttaga cggtgatgtt
     6301 ttgacgaaat ctttatccag ttcagatgct gaaaagaacg tgatcgatcc agataaaatt
     6361 agtagttcct tggaagattt tttatctaac aaagacaata ttttattcgg taatgattat
     6421 gtgtacacga aaaacttttc tcatttagaa gaagaaccac tagaaatcca agcaagccaa
     6481 gagtatgaag gcatcccatt caatgatgat acagcaaaaa tcgttctttc tttagaaaaa
     6541 aacgataatg attatagcat cacgaaatac atgcagacgc atttatctga tatcgagcag
     6601 ctgcgcgaaa agacggaact gtatacggaa gaggaagcaa tcaatacatt gtacatcaat
     6661 aacaaaatac caagaggatc aaaaatttta tggcgtcagc tagcttattc ctgtattctg
     6721 aaagtccggg aaaaaaatgt gtatgttcct gtttggcatg tagcgatcga aacaagcgat
     6781 aaagtggtcc aaattgagag tgtcaacgct ttcagcaata cgatcgtgac aaacaatact
     6841 gtaccaaaag tggaagatca ataaaaaagc gagtataatg aaaaaagttt acaaagtaag
     6901 aagggaagta ggagtcaaat ggctgaagaa aaaccagctt ttaaaatcag tatcctagca
     6961 agtggaagtt cgggtaattc actttatatc gaaagtgaaa aaaaacggct tttggtcgat
     7021 gcaggactta gcggtaaaaa aatcacttcc ttgatggctc aaattgatcg gacaccggac
     7081 caattagatg gaatacttgt gacgcatgaa catcgagatc atatacatgg cgtgggtgtc
     7141 ttggctcgta agtatcattt ggatgttttt gccaatcagc agacttggga agcgatggaa
     7201 ccactgattg gaaatgtacc agtggaacaa aaacatctat ttgagatggg gaaagtcaga
     7261 acattcggcg atatcgatat tgagagtttc ggcgtctccc atgacgcagc ggctccgcaa
     7321 ttttatcgtt tccataaaga aaatcggtca ttcgtcatgt tgacggacac cggatattgc
     7381 agtgattata tgcgaggtgt cattgaaaat gccgatggtt atttgatgga aagtaatcat
     7441 gatcttgaga tgttacgcat gggaccttat ccgtggaatt taaaacagcg tattttagga
     7501 gatagaggac atctttccaa cgaagacggt gcacttgtca tgactgatgt gatcggtaat
     7561 cggaccaaac gaatctatct tggccatctt agcaaggaaa acaatatgaa agaacttgct
     7621 catttaacaa tggaaaatgt tttgaaagaa aaagattttg gcgttggaca tgattttgaa
     7681 atctatgata cagatccaga tgaagcaact gagctatttt cgatttaaac agttcaatca
     7741 ataaaaatat aaaaagcaga agataaaatc aatcagggtt ggttttatct tctattttta
     7801 tttttttagc atattaaaaa aataaccgta ttatcgactg actacactga tgtgctgctt
     7861 ttcatgtttc tcatccagta tctcatctac taatgcaatc gcgtaatctg ccatgctgat
     7921 cgtactgtcg ccagcagcgt ttctttgtaa ataatcatca cttaacaaat aagtacctgt
     7981 acgtttgcca tgtggatcaa ataaagaagc tggactgata taagtccaat gtagattttt
     8041 agattgtttc aattttaaca atccttcgta catattgaaa gctgttggat agaagggtgc
     8101 atttttaggt acttggtcaa tcatacgagt cgtcttttct gtatctaaga ataacgaaga
     8161 ggcaccccca acgacaatta agcgtgtatc ggttccttca agcatctcaa tcaaatggga
     8221 caaagaagtt tgatgcattt cttcttttcc tttgggagcg ttgaaagcat caacgacaac
     8281 atcaaaagat gcaagatcag tagttgtcaa ctcaaataaa tccttttgta taaacggaac
     8341 atctgatggc aatttttctg gatgacgcac gattgccgtc acgtctaaat ctctggacaa
     8401 tgcttcgtct aaaataaatg aacctgcatg gccagtagct ccaatgagtg caattttcat
     8461 aaaaaacctc cttttttatt cctgtccatt gtaagcagtt gctgaatatt cgtcaaagaa
     8521 tccgattttt gaaaagctca gtgcgcattc ctttcatggt tcgtgatcat tgggtatagt
     8581 taaattaaga aaactgattg ataaaaatag aagttgaagg agataagaaa tgaaagagtg
     8641 gttagatcgt gcctttttac caatgataac atctgttgtg aatcttagac ccttaactgc
     8701 tttgcgtaat ggaatgactt acacgatccc aataattatt gttggctcgc tgtttttctt
     8761 atttgctcat tttcctgtgg attacatcgc tcagtggata gacaaaacag gattttctat
     8821 gtattttaca caagtatacc aggctacatt tgatgtgata gccttttgga tcgtttttgc
     8881 cattgcatac gcttatgcaa aagaagaaga catcgatcgc ttaccagtcg gcataacagc
     8941 cttgtctgct tatctactgc ttattcagcc actaaatact cagatagata ctgtctggac
     9001 aggtgctgaa gggatactag gagcagttac aactgggctc atcatcggat ggggctatgc
     9061 acgtttagta agacttgcga aagggtggaa gcaaagagag aagatacctg aaaatgtttg
     9121 gcagtctttt acttcattga ttccaatcat tgttatagtc acttttacgc ttatcggttc
     9181 agcggttttt caacagttgt tcagaatgac tgttgttcaa ggagtatgga catatgtcca
     9241 gcttcccatt caatcgttca tagacacgtt gtttggtgtg cttttattag gtttttttgt
     9301 tccgttttta tggttatttg gtcttcatgg atctgcgatg gtcaatgggt tggttagtcc
     9361 cgtcttgcaa gcgaattcat tagcgaatgc agaaatctta gcctcaggac aagagttgac
     9421 ggtggcaaat ggcggacata tcgttactca gcaatttctc gatcagttca tgacggttac
     9481 gggtgctgga ttgacgttag gggctgtatt ttttatgacg gtttttgcga aatcgaagaa
     9541 atacagagaa ttaggaaatc ttgctctttt accagccttt ttcaacatca atgaatcaat
     9601 tattttttcc acaccgatcg tgatgaaccc gatgatggct gttcctttta ttttcgcacc
     9661 ggtcgtttca ggattgatta cctattccgc tttatatttt ggattcgttc ctttatttac
     9721 agcagtccaa gtcccttgga caacaccgcc gatcctctcg ggtttcttag taggcggagt
     9781 gcctgcagcg attttacaag gtatcgtgtt gtcaattagt tttttcattt atttcccatt
     9841 tttgaaaaaa atagattctg caaactgcaa aaaggaaaga cagacaaaaa atgatggagc
     9901 agcagaaaag atgaacgact aaaaaacaaa aatactcctg tcgctttaga ttgggaaaat
     9961 caccaatcta ggatgacagg agtatttata gtcatgttta tactagccct ttttggacag
    10021 ctaattgaac aagaacaact aatgtgttca ttcctacgtg tgtgatcatc gatgtccaga
    10081 tccgaccagt tgctttgtac tctaggctga agaagaaacc taggaaaaag tagattagca
    10141 gatgaccatc attatgagca aacgcaaaca gcaaagagct gatcactgct ccgacccaaa
    10201 aatttgaata tcgactgatg atccccagta tactgcggcg gaatacgaac tcttccatga
    10261 tgggtccagc aacagttgtc gccaaaataa aagcgggtgc ttccatgatc atctggatga
    10321 tattttgtgt attctcggaa ggggttgctt tgccaaacaa tacagattct aacatgacag
    10381 cgatgctttg cagaatcaat gcgacaaaga ttccaaccaa tccataaata acaatctttg
    10441 gagcagaagc tttttttacc gctgattcga tcgctaaggg ttcacgttgc ttaaaataaa
    10501 aaatagctag gacaacggcg cctagtatat acatgactgc agttgctgtg atcaattcag
    10561 acgtagattt tacaagtcct atcgaagcta ggatcaaggg tgagataaaa attagaccat
    10621 agcaaaaaat gctgaggaag ctatattttt ttaaagacat gtaattcctc cttttaaggg
    10681 ataacaagca tgcaaggcaa gcttatatcg attgatttca attatatcat aatttcaata
    10741 agcagctgtc agaataaaat ttcttttctt tgatttaaaa gcttgcaaaa aagagggaga
    10801 atgagtatta ttaaaaatgt aggttagcac tcgaaggtta agagtgctaa cagattaaaa
    10861 aaagagttat cggagggatt tatcgtgtta aaaccattag gtgatcgcgt cattatcgaa
    10921 gtcgcaaaag aagaagaaaa aactgtcgga ggaatcgttt tagcttctgc tgctaaagag
    10981 aaaccccaaa ctgggacagt tgttgcagtc ggtgaaggcc gtttgttaga aaacggtgaa
    11041 aaagttcctg ccgctgtaaa agcaggcgac caagttatgt tcgaaaaata cgccggtaca
    11101 gaagtaaaat acgaaggaaa agaatatctg atcgtcgcag gaaaagatat catggcgatt
    11161 gttgagtaaa tttggaagat aaaaaaataa tcaaaaataa tcaatgaggt gaatcaatca
    11221 tggcaaaaga attgaaattt gcagaagacg cacgcgcagc tatgttacgc ggggtagata
    11281 aattagcaga tacagtgaaa gtaacattag gacctaaagg ccgaaatgtc gtactagaaa
    11341 aatcttacgg ctctccattg atcacaaatg atggtgtgac gatcgcaaaa gaaatcgaat
    11401 tagaagatca ttttgaaaac atgggtgcaa aacttgtatc agaagtagca tcaaaaacaa
    11461 atgatattgc aggagacggt acaacgacag caactgttct gacacaagca atcgttcgcg
    11521 aaggtttaaa aaacgtaact gcaggtgcta atcctctagg cattcgtcgc gggatcgaat
    11581 tggcaacaaa agcagcagtc gaagaattgc ataatatctc aactgttgtt gattcaaaag
    11641 aagccattgc acaagtagca gctgtttctt cgggttctga taaagttgga catttgattg
    11701 ctgatgcaat ggaaaaagtt ggaaacgacg gtgtcatcac aatcgaagaa tcaaaaggga
    11761 tcgaaacaga actagatgtt gtagaaggta tgcagtttga tcgtggttac ttatcacaat
    11821 atatggtaac agataacgac aaaatggaag ctgttctaga aaacccatat atcttgatca
    11881 cagacaaaaa aatctctaac atccaagata ttctgccatt gttagaacaa atcttgcaac
    11941 aatcacgtcc attgttgatt attgctgacg atgtagatgg tgaagcattg ccaactcttg
    12001 tattgaacaa aatccgtgga acattcaacg tagtagctgt aaaagctcct ggtttcggcg
    12061 atcgtcgtaa agcaatgctt gaagatatcg ctattttgac aggtggtaca gtaattactg
    12121 acgatctagg tttagaattg aaagatgtaa caatcgaaaa cttaggaaat gcttctaaag
    12181 ttgttgtaga taaagacaat acaacgatcg tagaaggttc tggagaaaaa gaagcaatcg
    12241 aagctcgtgt gcaattgatc aaaaaccaaa ttgctgaaac aacttctgat tttgaccgcg
    12301 aaaaattaca agaacgctta gctaaattag caggtggtgt agctgttgtt aaagttggtg
    12361 cagctactga aacagaattg aaagaattaa aattacgcat tgaagatgca ttgaatgcta
    12421 cacgtgccgc agtagaagaa ggaatggtct caggtggtgg tacagctcta gtgaacgtta
    12481 tcagcaaagt ttctgctgta gaagcagaag gagacgtggc aacaggtatc aagatcgttg
    12541 ttcgtgcttt agaagaacca attcgtcaaa tcgctgaaaa cgctggttat gaaggatcag
    12601 tgattgttga taaattgaag aacgtggaac taggcactgg tttcaatgct gctactggag
    12661 aatgggtaaa catggttgaa gcaggtatcg tagacccaac taaagtaaca cgttctgcct
    12721 tgcaaaatgc cgcttccgtt tctgccttgt tattaacgac agaagcagtc gttgcagata
    12781 aaccagaacc agcagcgcca gcagctcctg caatggatcc atcaatgatg ggcggtatga
    12841 tgtaagaaaa agcaacttgc ttatctacaa ctgatcatta gtgaaagaca gataaaaaga
    12901 ggctggaaca gaagcgttta actccaagaa ataagaagaa attcacggaa attgcttttc
    12961 aaatttttgt gaatttcagc ttatttccga aggagttgct tctgcttccg ctgtttatac
    13021 gtgtttagag cgtgagacaa aagtgttctt tacttttgtc ccacgctctt ttttgtgtgt
    13081 aattataatg aaaatagtta tttttaatag ttataatatt ttatctatta aaagtaaata
    13141 tccattc
//
LOCUS       DAYNVV010000069        13135 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.072, whole genome shotgun sequence.
ACCESSION   DAYNVV010000069 DAYNVV010000000
VERSION     DAYNVV010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13135
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.072"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..456
                     /locus_tag="ACGXWR_002331"
     CDS             <1..456
                     /locus_tag="ACGXWR_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803855.1"
                     /translation="AERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQEH
                     KNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGKS
                     YGKEIQTALPSEEFALGNSFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            517..1986
                     /locus_tag="ACGXWR_002332"
     CDS             517..1986
                     /locus_tag="ACGXWR_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFK0803856.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVGDDRLDHAVAFLWKDPQTGETVGASYQGTIVDFNRFGKRGTYKHIDKNPTPNHGFN
                     LKIGDPKHLKFFESSIDLLSYAALNREKLQDAWLVSMDGLKHHVISHYVEESISELRR
                     KQTFPQSIEICVDNDRAGHIFYEKEQMKGIVDPFTNKKIRCERGIPNDWQVPKEYKAT
                     YEAVAKEMSVEPEAIMAIHKTETNLQLTNQLVSAHDVQSTFGKMLAKGEPVETIDLKE
                     ACTTVAKELKVCERADGTYNFDRFYSRKANIKDVNAGILLSYKAEQYYKGYKKHEHEF
                     VPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            1997..4201
                     /gene="topB"
                     /locus_tag="ACGXWR_002333"
     CDS             1997..4201
                     /gene="topB"
                     /locus_tag="ACGXWR_002333"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFK0803857.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFTGETVIT
                     YGFGHLVELDSPDMYDEKWKQWALEHLPIFPNQYHYHVPKDKKKQFSVVKRQLQSADT
                     IVIATDSDREGELIAWSIIQQAGANQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEVQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEAYLKEKGVQLGKQPGTILQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ENDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            4217..4366
                     /locus_tag="ACGXWR_002334"
     CDS             4217..4366
                     /locus_tag="ACGXWR_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803858.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            4440..5033
                     /locus_tag="ACGXWR_002335"
     CDS             4440..5033
                     /locus_tag="ACGXWR_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFK0803859.1"
                     /translation="MKDKIQCIFDKHNGNLSLKDARSEGLSPMTLDRLAEKDKIEKVA
                     PGFYTLKDAFVDELYLAQSIYSRGIFSHETALDLFQVGTYIPKKINMMFPKGYNVSKE
                     KLDQYAIQPHYTNKENFDLGVTETESFYGNKILVYDLERTLCDMWNPRYKASVEVKQE
                     ALKEYMTSTSRNTNKLRRYMDILKSPKEMTLYMLPLY"
     gene            5049..5948
                     /locus_tag="ACGXWR_002336"
     CDS             5049..5948
                     /locus_tag="ACGXWR_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFK0803860.1"
                     /translation="MTPTQFKEKTRNFAAEKHLNPQIVQRYYMMEKLLECIVESPYHD
                     DFVLKGGFLIGSKYGLENRSTVDIDTTYRNSKLTKEKLETVFSELTANPTKDGIRFEL
                     KGLTETREADYYPGFQAKFIAYLENARVPFKLDITSGDSIIPAALMYEHKLMFEDKTI
                     HIPAYPTEQILAEKLHATFSFGKDNSRMKDFYDLYMIPKLERIDEKNLYKSVQGTFKE
                     RNNQSVFKHLYDQEMPQLVKDEGLREKWKRYQQENYFAKDISFESTLTSVDSLMQSIV
                     EQEKAERKQNFKRSQQMNQEMER"
     gene            5951..6436
                     /gene="ssb"
                     /locus_tag="ACGXWR_002337"
     CDS             5951..6436
                     /gene="ssb"
                     /locus_tag="ACGXWR_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFK0803861.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFSLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRMHADQSSSSPSPTTFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            6802..7062
                     /locus_tag="ACGXWR_002338"
     CDS             6802..7062
                     /locus_tag="ACGXWR_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803862.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            7503..7709
                     /locus_tag="ACGXWR_002339"
     CDS             7503..7709
                     /locus_tag="ACGXWR_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFK0803863.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            7709..7960
                     /locus_tag="ACGXWR_002340"
     CDS             7709..7960
                     /locus_tag="ACGXWR_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803864.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYEIEYWLTKLEN"
     gene            7975..8412
                     /locus_tag="ACGXWR_002341"
     CDS             7975..8412
                     /locus_tag="ACGXWR_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803865.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFESIEKNGAFYTIESEEKDNE"
     gene            8405..9112
                     /locus_tag="ACGXWR_002342"
     CDS             8405..9112
                     /locus_tag="ACGXWR_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803866.1"
                     /translation="MNKVVYQLTTEDVSQFLTSKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNHLDVYKRRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGK"
     gene            9277..9477
                     /locus_tag="ACGXWR_002343"
     CDS             9277..9477
                     /locus_tag="ACGXWR_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803867.1"
                     /translation="MNKIIPLLFVLFVGEILMRHAAAVHLNFVVFLGILVFCLIFWRF
                     VLALVSLLFKMIAAIFFIGLFR"
     gene            9493..9672
                     /locus_tag="ACGXWR_002344"
     CDS             9493..9672
                     /locus_tag="ACGXWR_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803868.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            10013..10276
                     /locus_tag="ACGXWR_002345"
     CDS             10013..10276
                     /locus_tag="ACGXWR_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HFK0803869.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            10270..10620
                     /locus_tag="ACGXWR_002346"
     CDS             10270..10620
                     /locus_tag="ACGXWR_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFK0803870.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(10644..11258)
                     /locus_tag="ACGXWR_002347"
     CDS             complement(10644..11258)
                     /locus_tag="ACGXWR_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFK0803871.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRL
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            11572..11994
                     /locus_tag="ACGXWR_002348"
     CDS             11572..11994
                     /locus_tag="ACGXWR_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803872.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            12004..12207
                     /locus_tag="ACGXWR_002349"
     CDS             12004..12207
                     /locus_tag="ACGXWR_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803873.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            12418..13002
                     /locus_tag="ACGXWR_002350"
     CDS             12418..13002
                     /locus_tag="ACGXWR_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFK0803874.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         4754 a         2142 c         2625 g         3614 t
ORIGIN      
        1 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
       61 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
      121 aagcaggagc ataaaaatac tgtagaaacg gcagaacaaa agaatattgt tcctgttggt
      181 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
      241 catttgaagg atgcggcgtt tattgaagat ccacagcata atcaagtaat tttaaaagga
      301 aaaagttatg gaaaagagat ccaaacggcg ttaccttcag aagaatttgc gctaggaaat
      361 tcattccgat tttcacttga gacagtgtca gaagtggcaa aacgaaaaaa tgaaatctat
      421 tatgaacaac aattgtcaca aaaagaacgt gtataaaaca agtaaaaaag actatctgaa
      481 aaacggatag tcttttttct tttgggaggt tttaaaatga ccgagaaaaa aatgagtctt
      541 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
      601 gtcaataaag gacgagacta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
      661 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
      721 ctttttttca tagacaaaga gatccaagac cctaagcaac aatttaaagc agccactgat
      781 tttattctaa agaatgaaga caaaacagaa cgagtggaaa atcttcattt tgagacagaa
      841 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
      901 aaggaagaac gaaaactacc agagtggctg attgattatg cagaaaaaga agggttgatt
      961 gctgaactaa agccgaaaca tgaacggcaa aattttttag ttggagacga ccgtttagat
     1021 catgcggttg cttttttatg gaaagatcca cagacaggag agacagtagg ggcaagttat
     1081 caaggaacga tcgtcgattt taatcgtttc ggtaaacggg gaacgtataa acacattgac
     1141 aagaatccta cgccaaatca cggatttaat ttaaaaatag gcgatccgaa gcatttaaaa
     1201 ttctttgaaa gtagtattga tctgttaagt tacgctgcat tgaatcggga gaaactacaa
     1261 gatgcctggt tagtttcgat ggacgggtta aaacatcatg taatcagtca ttacgttgaa
     1321 gagtcgattt ctgaattaag acgaaaacaa acatttcctc aatcgattga aatatgtgtg
     1381 gacaatgatc gtgcaggaca tattttttat gaaaaagaac agatgaaggg aatcgttgat
     1441 ccttttacca ataagaaaat ccgttgtgag cgaggaattc caaatgattg gcaagtacct
     1501 aaagaataca aagctactta tgaagcagtc gcaaaagaaa tgagtgttga acctgaagca
     1561 attatggcca tacacaaaac tgaaactaat ttacagctga caaatcaatt ggtgtctgct
     1621 catgatgttc aatctacgtt tggaaagatg ttggcgaagg gcgaaccagt agaaacaatt
     1681 gatttgaaag aagcatgtac cacggtcgcg aaggaactga aagtatgtga acgcgcagat
     1741 ggaacataca actttgatcg tttttatagt agaaaagcca acataaaaga cgttaatgca
     1801 ggaatccttc tttcctataa agcagaacaa tactacaaag gctataaaaa gcatgaacat
     1861 gaatttgtac ctgaagtgaa aaaggattgg aatgatcaat tgaagcatga gatccagcaa
     1921 caagaaatca gaaagcaaaa acgtgcgatg ttgtttcaac aaggcagaca acaagaaagg
     1981 gagtgaagtc gtcactatga aaaccgtcat tttagcagaa aaaccgtcac aagcgaaggc
     2041 ttatgccgat agcttttcta aagctacccg aaaagatggg tattttgaga tccaagatcg
     2101 attgtttaca ggagaaactg tgatcacgta tggttttggt catttagtcg agttagattc
     2161 gcccgatatg tacgatgaaa aatggaaaca atgggcatta gaacatttgc ctattttccc
     2221 caatcaatac cactatcatg ttcctaaaga taagaaaaag cagtttagtg tcgtcaaacg
     2281 acagctgcag tcagctgata cgattgtgat cgcgactgat agcgatcgtg aaggggagct
     2341 gattgcctgg tcaatcattc aacaagcagg cgccaatcaa ggaaaaacct ttaaaagact
     2401 ttggatcaac tccttagaaa aagaagccat ttatcaggga ttccaacagt tacgagacgc
     2461 agaagagacc tatccaaaat ttgaagaagt acaagcacgt cagatcgccg attggttaat
     2521 tgggatgaac ggtagcccac tgtatagttt actcttgcag caaaaaggca taccaggaag
     2581 tttttcttta ggtagagtcc aaaccccaac actctatatg atttatcaat tgcaggaaaa
     2641 gattagaaac ttccaaaaag aaccatattt tgaaggaaaa gcccaagtaa tcgctcaaaa
     2701 tggcgcattt gatgcgaagc ttgatccaaa tgaaacccaa gcgacacaag aagcatttga
     2761 agcctattta aaagaaaaag gtgttcaatt aggaaaacag ccaggtacga tccttcaagt
     2821 cgaaacagag aaaaaaagtg cggctagccc acgtcttttt tctttatcga gccttcagtc
     2881 taaaatgaat caactcatga aagctagtgc caaagatact ttggaagcca tgcaagggtt
     2941 gtatgaagga aaatatctaa gctatccgcg aacggatacc ccttatatta cggaagggga
     3001 atatgcgtat ctgttggatc acttagacga atacaagcat tttttaaaag ccgaagcgat
     3061 tccgactcct attcatacac cgaatagtcg gtatgtgaat aataagaaag tccaggaaca
     3121 ttacgcgatc attcctacaa aaacggttat gacagcagcg gcttttgaac aactaagtcc
     3181 actgcagcag gccatttatg aacaagtgtt aaaaacaacg gtggccatgt ttgcggaaaa
     3241 atatacctat gaagaaacaa cgatcttgac gcaagtccag cagcttcagt taaaggcaat
     3301 cggaaaagta ccgatagatc taggttggaa gaagttattt ggcaaagaga acgacggaaa
     3361 agagaaggaa gaagagccgc tacttcctaa agtgacaaaa ggagaaatgg tgacggtaga
     3421 tctacaagtc cttgaaaaag aaaccaagcc accacagcct tataccgaag gtacgttgat
     3481 cacggcgatg aaaacagctg ggaaaaccgt tgatagtgaa gaagcgcaat ccatattgaa
     3541 agaagtggaa ggaatcggta cagaagcgac acgggcgaat attattgaaa ccttgaaaca
     3601 aaaggaatat atcaaggtag agaaaaataa gctcgtggtg acgaataaag ggattttgct
     3661 ttgccaagcc gtggaaaaag agccgctgct tacgagtgcc gaaatgaccg ccaaatggga
     3721 aagctacttg ttaaagatcg gtgaacgaaa aggaacacaa accacttttc tagccaatat
     3781 ccaaaaattt gtctctcact tattggaagt cgtaccaggg caaatccaat ccactgattt
     3841 tggatcgacg ttacaagaag tgaaagcagc cagtgaaaag caagaagccg cgcgtcattt
     3901 aggaatttgt ccaaaatgcc aggaacaaga agtcttactc tatcaaaagg tggcagcatg
     3961 tacgtctgaa gcctgtgatt tcaaactatg gacaacgatt gccaaaaaga aacttacagc
     4021 gacacagctg aaagagatca ttcaaaatag ccgaacaagc caaccagtga aagggttaaa
     4081 aggtcagaag ggttcgtttg aagcaacgat tgttttaaaa gaagacttca ctacaggctt
     4141 tgaattttct gaaaagaaaa aaacgaactt caagaaaaga acacgacgca ctacaaaata
     4201 atggagggtt aatcttatgc gtaatacaac acacaaacaa caagaaatcg aaaatcaaaa
     4261 agccaaaatt cgttcagaac aggaaaaaat gcgtgccagc aaacgaagac tgcagcaatt
     4321 gaagaaccag cagcggattc aaaaagaaat cgaattagat cgataaattc ctttcttgtt
     4381 aatataaaac taacatgtta tagttgtgtt agttttatat taactttagg ggaagagtaa
     4441 tgaaagacaa aatccaatgt atttttgata aacataatgg caacctatcc ttgaaggatg
     4501 ctagaagtga aggattatcg cctatgacgt tagatcgatt agccgaaaag gataaaatag
     4561 aaaaggtagc accaggtttc tataccttaa aggatgcgtt cgtggatgaa ttgtatctcg
     4621 ctcagagtat ctattccaga gggatttttt ctcatgagac tgcgctcgat ctttttcaag
     4681 taggaacata tatccctaaa aagatcaata tgatgtttcc taaaggatac aatgtatcaa
     4741 aggagaaatt agatcagtat gccattcaac cgcattacac taataaagaa aattttgacc
     4801 tgggagtcac agaaacagaa agcttttacg gcaataaaat tttagtctat gatttagagc
     4861 gaacgttatg tgacatgtgg aatccaagat acaaagcaag cgtagaggta aaacaagaag
     4921 cattaaaaga atatatgaca agtaccagta gaaatacaaa taagctaaga agatacatgg
     4981 atattttaaa atcaccaaaa gaaatgactt tgtatatgtt gccactttat tgagaggagt
     5041 aaagatgaat gacaccgaca caatttaaag agaaaacaag aaatttcgca gcagagaaac
     5101 atttaaaccc acaaattgtc caaagatatt atatgatgga aaaattatta gaatgtattg
     5161 ttgaatcgcc ttatcatgat gattttgtat taaaaggggg atttctgatt ggatcaaaat
     5221 acgggttaga aaaccgttca accgttgata ttgatacgac ttatcgaaat tcgaaactaa
     5281 caaaagaaaa gttagaaact gttttttctg aattaacagc taatcctaca aaagatggaa
     5341 ttcgttttga attaaaggga ttaacagaga cgagggaagc cgattattat ccaggttttc
     5401 aagcaaagtt tattgcttat cttgaaaatg cacgtgtacc ttttaaatta gatattactt
     5461 caggtgattc tattattcca gcagcattga tgtatgaaca caaattaatg tttgaagata
     5521 aaacgattca tattccagct tatcctacgg aacaaattct agctgaaaaa ttacatgcca
     5581 cgtttagttt tggaaaagat aattcgcgca tgaaagattt ttatgacctg tatatgattc
     5641 cgaaattaga acgtatcgat gagaaaaatt tgtataagag tgttcaagga acattcaagg
     5701 aaagaaataa tcaatcggtg tttaagcatt tgtatgatca ggaaatgcct caattggtga
     5761 aagatgaggg cttgagagaa aagtggaaaa gataccaaca agaaaactat tttgccaaag
     5821 acatttcttt cgaatctaca ctaacttccg ttgattccct gatgcaatca attgtagagc
     5881 aagagaaggc agaacgaaaa caaaatttta agagatcaca acaaatgaat caagaaatgg
     5941 agagataaag atgatcaata atgtaacttt agtagggcga ttaactaaag atccagattt
     6001 acgttatacc gcaagtggca cagcagtggc gactttttcc ctagccgtta atcgtaattt
     6061 cacgaatcaa aacggcaatc gagaagctga ttttatcaat tgcgtgattt ggcgcaaacc
     6121 agcagaaacg atggcgacat tagctaaaaa aggcagcttg atcggcgttg tcggacgaat
     6181 tcaaacacgg acttatgaca accagcaagg acaacgtgtg tatgtgacag aagttgtggc
     6241 cgataacttc caactattag aaagtaaagc agcgacagaa agccgtatgc acgctgatca
     6301 atcgtccagc agtccaagcc ctaccacctt tgaacaacgg gatacagcga cgcctaacaa
     6361 caatggattg aacgcttcac agaatccatt tggtggacaa tcaatcgata ttagcgatga
     6421 tgatctaccg ttctaagtag cattttctat tggttgcatt tgctacggtt tatgttataa
     6481 tttagacaac aaaaagaatt ttcaatctat aaccaaaaac cactagctgg cgggctagtg
     6541 gctttctttt acgtttctat tataagaatt aacgggtagg cttactgtct ttcttggcaa
     6601 atttacaatc aagccatttg cagatatagt gcgcggctac ttctgccatg attgcaaaaa
     6661 caaaatcaaa aagaattttc aaacctataa cctcctcccc ttgccagatt aggccggggt
     6721 agcagacagc aagactatta tagcataatt gaaatatcca aatgattgga tttttgctat
     6781 aattttagcg aggtgattgt gatgaacaaa tatgttggtt tgcttgataa aatccgagta
     6841 ataaaaacgc aaccgttatt ggttcgcttt actttacaaa cgattcatga atcgattaat
     6901 tgtgtagttg cagatattga aattatcgat aaattgctaa ttatggatga tggaaaatac
     6961 aatattgccg tcacaggtca cttcaataaa cgaaatcagc tagttattgc tagcatgtat
     7021 gttagaaatc ccgatcattt tacgcgatcg atgggcatat aaataaaaga agagttgtag
     7081 tcctaaatga ggattgcagc tctttttgtt ttacatagaa acaggaaaag acctttttag
     7141 gaagacacaa gtgccttctc aattgaaaaa cctttctctc actccaaccg ccaccgccgt
     7201 tcgagaagaa aggaagtgaa cgctgcacgt tcactaagat atggtgtctt gcaaagcaag
     7261 acaaaataga caaaacttcc tctcaccaaa aggttcgttc ctgttcgtta tctctttatt
     7321 gatttgccag accggcaaca agttgccttt tatcaccaaa aagcgacaag gacaagggta
     7381 aatggcacgc tgcgcgccct tgtccttgtc gcttttcgtt gatttattct ggccaacaaa
     7441 tcaataaaga aagaactaac gaaaggaagt aaaacctttc ctaagaggag gcagaatcaa
     7501 acatgcgaaa gaaatttgat tattggggtg ttcccttcag cgaattattc ccaaactatc
     7561 atgcaccaca tactgttgaa tgcgattgtg gagaaagagc gaaatgtatc aaaagctatc
     7621 gtttgtatca atgtccaaca tgcgggaaaa aatatacctt gtcttatggc gattacattt
     7681 tgattgatga gaaaggaaag aaacgctgat gaaaacacaa cacaaattat tgactgtaaa
     7741 agaagtcgtt caaattttgg tggacaaaga agtcatttct gaaaaagtag cagaagcttt
     7801 acttattccg cggtactgga cgatagaaac ccctttagta gaggatgcac cgactatgct
     7861 atttgaagac ctagtgaaga ttgcaggata tgaactgcat tatcaagaaa acatggaaac
     7921 ttatgaaatc gaatattggt taaccaaatt agagaactaa aaaggagaaa aaatatggct
     7981 caaaattact atgacgaatt tgtcaaatta cctttggata aaatggcaca aaaaatggag
     8041 gatatgacgt tcctatacca tgaaacacgt gtacccaaaa aacattacaa ggaaaaattg
     8101 tcagtcgcag tggaagaaat gattgaatca ggtgtcgaaa tgaatctcat tgcgacgtac
     8161 tatcgaacac tggaagaact gaaaaaacaa aatggaaaat ggtttttcca agccttacta
     8221 tgcttggaag taggtgtcaa accaagcact atcaaacctt ccgaatatca agccttagaa
     8281 ctgacttatg caaaattcgc acagattaag aaagctaaag caatggctag cgactggcta
     8341 gatacttttg aaagtatcga aaaaaatggt gcattttata cgattgaatc ggaggagaaa
     8401 gataatgaat aaggtggttt atcagctaac aacagaagat gtttcgcaat ttttaacaag
     8461 caaagaacac ttgaatgaag taatcagacg gattcaaaaa gactttagtt gtatggaaga
     8521 aatgaagtac tttattcaaa gagtggaaga acagttgtat atggaaagcg aaacaagtca
     8581 aacgaaggtc acagtcagcc ataatcattt agacgtgtat aaacgtcgtc ctgaaacggt
     8641 aaaaaaagga acagagcttc tacgactaga aacagaaaaa tacatcatga atgtgtacct
     8701 agaaaggagt gagctggtcg aaaactttgt cagctacacg atttgtagga aacactatta
     8761 ctcagaatca gaatattatt caattttcga gagcatggaa ttaatggaag aagaaatgga
     8821 agagctaaac agcaaaaatg cgacggtaga cgattattac cttgtattta ctaggttttt
     8881 gacgtgtggg acggaatcta tcgtgttaat gggaatggat tatgaactcg ctgtacccga
     8941 agcatttttg agggaatatg tagaagaagt agataaccca ggcgacgact ggtacacgac
     9001 tttaactgat tttttagaca cctacactta cgacgataca gaagaaatcc aaaatgaact
     9061 tgaccgtaaa cgaatgccat atcaacgatt tgaaaggaaa aaaggtaaat aaccatttat
     9121 accgaaaagt gaggatgtgt gaaataagaa caaaaaacct tgaaattaag ggaatggttc
     9181 ttatttcgca ccaatcgctc caaccgcccc cgccgcttag gtggtgcgaa ataagcgggc
     9241 aaagcccgat aacctaagag aaagaaggag atccatatga ataaaatcat tcctctattg
     9301 ttcgtactgt ttgttggcga gatacttatg cgtcatgctg cagctgtaca tttaaacttc
     9361 gtagtattct taggaatact ggtattttgt ttgatctttt ggcgatttgt attagccctt
     9421 gtgagtctac tattcaagat gattgcagcc atatttttca tagggttatt tcgatgaaag
     9481 gagagagtac taatgccaat tgcaatagga aataaacggt tacccgtgac attagatgaa
     9541 aagagacaaa aagaattgca gcaactaaag cagaagtacg gaaaaagtga atctaagatt
     9601 atgtgtattg cgttagatct attgatcgcg caagaaaaag caggatttga tataccagca
     9661 ctaaaaaagt gacgtcactt ttcatttgaa gaaacaaaag tgatagcact taattgttcc
     9721 tactatttag aatattttct atgtcctttt tattccattt tgtatcaata actatgaaat
     9781 ctttaaagta tccagaagag attattttta gatcaatttt tttcttacct gattctaaag
     9841 attttgtttt cttaaacata ttatgatttc ctttcgacta ttttcatata aatgttaaca
     9901 tagtttatgg attcatggaa tgttaatcta atttaataga aaaggataat taagtatata
     9961 cgttttttct tatgtatgtt atactatgta tatacagaaa gaggtgtcta ctatggaaat
    10021 gttacctata aaaaaatggg gaaatagtaa tggccttaga ttgccaaagt atattatgga
    10081 atatcttgga attcatacag aagacaaagt gaagataata caagaagaag taaacggtca
    10141 gaagcggcta attatcgaag cggctaatat agaaaatgaa ttaacaattg aacagttatt
    10201 tgaaaattac actgatgaaa gaaatcatgt gacgattcaa aatttaggtg aagcagtagg
    10261 taatgaaaaa tggtgagaaa acctagacaa ggcgatattc tattattgaa tacagcacct
    10321 cgatctggac acgaacagac aggtaaaaga ccttatattg ttttaagtca tgatattatt
    10381 gcggattata gtaacgttgt tacagttgct ccaatttcta gtacaactag aaactatccg
    10441 ctatatgtaa atataaactc agaatatgaa atgaagacaa caggaaaagt attattagat
    10501 caactaacga caattgatta tgaagccaga gagtgtattt ttttggaaaa agcgcatgat
    10561 agtttagttg aggagttatt gatgaaagtt agaacagttt ttcaaaaagt aagcaaataa
    10621 aatagaaaca gcagcatgat caactattcg tgattgacca tgctgtcttt ttttattcta
    10681 tatacggttt gtctcgtaac attgtagtct tttgcaatct tagcgatcgc aacacctttt
    10741 tttagatcct caacgatgtt tttataaaca agacgacgtt ggggatcttt tgcattggca
    10801 ctgtatagct taggacgtcc tttataaaca ccgttcgctt ttgcaatctt aatgccttgt
    10861 gcctgacgtc gtttagattc ggtacgttct tgttcagcga tcatggccaa aatttgaatg
    10921 atcaaatctt taatgaattt atccaggaga ggattgccaa ttgcttcggc catgatcggt
    10981 agacttgtga tgatcagctg cacatttttc ttcttcaagt aattgactga agcgatgatc
    11041 tcgtcgtaat ttcttccaag tcgatcaata gcttccacaa taaaaatatc ttgatctcgg
    11101 acgaaatcca gtgcttcttg aaaaacaagt cgatgagtaa tcgttgcgcc agattgtttc
    11161 tcaatgaaaa ttctctctgc accgaatttt ttcatttctt caatctgccg ttgttcattt
    11221 tgatcgatgg atgagacacg tatgtatgca actctcaaaa tttttaccta ctttctgcaa
    11281 ctatttaaaa aacaccctaa tcatacacga gaaaaccaga tttttcaatg tcgcggtcgt
    11341 gtctagttag ggtatacctt atatagacaa aaactaatga tggaggaaat agtatgtgtc
    11401 acttttcttt ttaaatggca atattttttg taaataaatg tcaatcaaga aaatttaaac
    11461 gattatgaca ttaaaaatat attttatgaa ttttctagta tataacttga tttatctgtt
    11521 aagatttatt aagaaaacgt tttcttattt ttgatttcga ggtgatagac aatgaaaaat
    11581 aagtttattt tatctttagg tattttaact attggaatta gtgtaactgg aactacaatt
    11641 cctacatttg ctgatagtac aaatgaacca actactgtag tagataataa ccaagaatta
    11701 actcctttag ataggaacgg aatagccatt ggtaacccaa ctaacgactt aactgttact
    11761 gaaaattatt taatagtttc tccattactt gctcgagcag cttctaaaac gatacgagtg
    11821 acaggaacga tgatttttga taaagttggt tggccttcta gacctcctca atcacggaat
    11881 tggaaagaaa aaagaaatgg ttattggtac tatggaaaat tgtatttaca aagttataaa
    11941 tcagctggaa acaattggat tgcgacttat tcaggaacct taactagaaa gtagggattt
    12001 tttatgccag aatttgtgaa cacaccaaat ttttatcaag atagcgatat tctaagtaaa
    12061 attaatttac cgaaagaaga atcagcttta caagttcagc gaactttaca ggagacacaa
    12121 aaaattcaaa aatcaatttc taatctagaa gattctgaag aaaaaagaaa aaaaagagac
    12181 caaaaaacat atcaaaaaga aaaataatga ttttaaaaaa agagtgtcta gtcgacattc
    12241 tttttttcta attgaaagtg ttcataaaat cacccatttc tggacacttt ctttttttgc
    12301 tttatttttc aaaaaaacaa ttcatttcat gttcataaac ccataacaat atctatgttc
    12361 agttaaacta tatggataaa gttatgttac aataaaatta atgaaggagt gatttttttg
    12421 aaaataggat acgcccgggt atctactggt ttacaaaatt tggatttaca agaagacagc
    12481 ctaaataaat ttggttgtga aaaaattttt actgatcata tgagtggggc aaaaagtaat
    12541 cgaccaggat tagaaatggc cattgatttt gttcgctctg gcgatacact tgtcgtttgg
    12601 cgcttagatc gtttaggtag aaatatggaa gatttgattt caatcgtcaa tcgactgaat
    12661 gagcgtggtg tgagttttca tagtattcaa gaaaatatta cgatggacaa atcaagttct
    12721 acaggacagc tcatgtttca tttgtttgcg gcatttgcag aatttgagcg taatttgatc
    12781 ctggaacgat ccgcagcagg acgagcagct gctcgtgcaa gaggacggtt tggtggtcgt
    12841 cctgaaaaat tgtctgaaca agatttggaa ttactgaaga ctttagtgga tagcggtaca
    12901 cctattaaga ctattgcgga acggtggaac gtctcaagaa ccaccattta tcgttatttg
    12961 gcaaaaatgg aggagaaaaa tggaaagaca aattctcatt agtttttgtc atttaatgct
    13021 gaaaattttt gccatttatc tagaaaagtg acaatagtat gagaattttt tgtaagtgtc
    13081 tactgataac ttattctcaa atgttgtaag gattttattc atttgttaat attaa
//
LOCUS       DAYNVV010000070        13084 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.073, whole genome shotgun sequence.
ACCESSION   DAYNVV010000070 DAYNVV010000000
VERSION     DAYNVV010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13084
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.073"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(78..2198)
                     /locus_tag="ACGXWR_002351"
     CDS             complement(78..2198)
                     /locus_tag="ACGXWR_002351"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFK0803875.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2428..3606
                     /locus_tag="ACGXWR_002352"
     CDS             2428..3606
                     /locus_tag="ACGXWR_002352"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HFK0803876.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3622..4380
                     /gene="aroD"
                     /locus_tag="ACGXWR_002353"
     CDS             3622..4380
                     /gene="aroD"
                     /locus_tag="ACGXWR_002353"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFK0803877.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4403..4888
                     /gene="ybaK"
                     /locus_tag="ACGXWR_002354"
     CDS             4403..4888
                     /gene="ybaK"
                     /locus_tag="ACGXWR_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HFK0803878.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4959..6212)
                     /locus_tag="ACGXWR_002355"
     CDS             complement(4959..6212)
                     /locus_tag="ACGXWR_002355"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFK0803879.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6328..7677
                     /gene="gdhA"
                     /locus_tag="ACGXWR_002356"
     CDS             6328..7677
                     /gene="gdhA"
                     /locus_tag="ACGXWR_002356"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HFK0803880.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7789..9135
                     /locus_tag="ACGXWR_002357"
     CDS             7789..9135
                     /locus_tag="ACGXWR_002357"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFK0803881.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9443..9829)
                     /locus_tag="ACGXWR_002358"
     CDS             complement(9443..9829)
                     /locus_tag="ACGXWR_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFK0803882.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(10097..10246)
                     /locus_tag="ACGXWR_002359"
     CDS             complement(10097..10246)
                     /locus_tag="ACGXWR_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803883.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            10708..10920
                     /locus_tag="ACGXWR_002360"
     CDS             10708..10920
                     /locus_tag="ACGXWR_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803884.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(11198..12997)
                     /locus_tag="ACGXWR_002361"
     CDS             complement(11198..12997)
                     /locus_tag="ACGXWR_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HFK0803885.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRSFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT         4291 a         2353 c         2577 g         3863 t
ORIGIN      
        1 tattctaaga tttctcttta ccaacatcat ttgacaaaga gcctaatttt gtcgctgctc
       61 cttttaaatt tattttatca ttcggaagaa cttgtggtcg ttccgtgaag ttcttggtac
      121 gtttgcgttt tataaagatc aacagttgat tgtcccttgt gttcactaaa gacactagtt
      181 gacttgtcac caagagattt ttcagcttct tttaatttct ctaagccatt cttgtagtca
      241 taatcactgg tatcaattgg gtctaatcca ctattcgtat agaaccgaag aagatcacca
      301 ttattgattt ggtcagaaac agctaactgt ttatcaactt tttctttcag tgaatcaatt
      361 tcattctgta cttcctcagt aggttcagta atagcttcac cagtttcgtt actatagatc
      421 gtaccaccgt agtaagtata ttttggtgta acaaaatcac catcacggaa agaaacaagc
      481 tgttcatgat ctttcgagaa tagatcttgt cctaactgaa tataattttt tgtatctaca
      541 cctagtaagt gaagtaatgt aggcaaggca tcaacttgtc cgccgtaagt gtgattgatt
      601 ccgccctgtg tttgtccagg gatatggatc atataaggga cacgctgcat ttgtgcattg
      661 tcgtagtttg tccaagtaga acttgttttt ccaactaatt cagctagatt tttatttctt
      721 gaattcgaga caccgtaatg gtcaccgtaa aggacgatga ctgaattatc atacaagccg
      781 ctttctttca aataattgaa gaattcttgt acggcggtat ctaaataatt ggctgtcgca
      841 aagtaaccgt tgatcgtttc atcatttgta ttggctaacg ggaatcctgc ttcgtcattg
      901 gtgaattttg aataaggata atggttagat acagcaatga attttgaata aaatggttgt
      961 tgcagacgtt ccaagtattg tacggattgt tggaaaaatg gtttatcatg caacccgtat
     1021 tggaacgaat tgtcatcatt aacatcataa taagaagaat caaagaaata atcatatcct
     1081 aaattcttgt atgtctcgtt tcgattccag aatgtaccag cgttcccatg gaataccgca
     1141 ctagtgtaac cttgtgtttg acttaaaata tcaggtgcag cttggaaagt attttttccg
     1201 cctaattgtg tgaacaagga gccttgattc aagccaaaca atgaattttc catcagcgtt
     1261 tccgcatcgc ttgtttttcc tgcttttact tgatggaaaa agttgtcaaa actgaacgtg
     1321 ctgttgctgt ggtaaagact attgatgaaa ggtgtaactt caagctggag accattctca
     1381 tctgtcaatt tataatcgat caggaattgc tggaagcttt ctaaatggat ataaatcaca
     1441 ttttttcctt tagcgagccc gaacaaatca tcatttggtg ctgcataatg ttcttttaca
     1501 taattttcta cttctttcat atcattggga cttgcttctg cccgcacttg gtttgtctgg
     1561 taagtttgaa caccgtcata aaccatgaaa gcattcaagc caagatattt gaccaaataa
     1621 tcacgagaga atgttcgagt cagcaattct ggacgatcag cttccgccat aaaaagattt
     1681 cctgagaaaa tcataactgc taatgtagag atcgcaaaag ccattcttgc tcggatcggg
     1741 cgagggtcca acttgatttt ttttgcaatc agcagaacag tcaagataat aaaatcgatc
     1801 caatagatca catcatatgg gcgaaacagt cgaatggcac tttctcccag accactcgct
     1861 actttcccag cacctaaaat cgtgttgatc gtaatgaagt ccgtgaattc tcgataataa
     1921 gtgacattcg aaaaaacaag caatgtcaaa agaaaataaa tgaccatcat cgtgatataa
     1981 gcaactctag ggcgtctgat ataaagagca attccaagta ataacaatgt agttgcaata
     2041 gggttgataa acaagataaa gtattgaatg ccactttcga ttccgagatg gaaatcaact
     2101 aaataggcaa aaatcgtttt caaccaaagt aaaacaacta gtaaagaaaa aaatccgagc
     2161 ctcttattca aaaaggcagg tgtttttata catttcaaga taatcttcct ttctgcactt
     2221 cttaatcaca gaagtgtcat gaaaccatgt tacacagctc acttattctc atttatttta
     2281 ctagtatgac aatatagtgt caattgaaac cagaagttta tgctgtttca ttaaggtttt
     2341 ctttaagctt catgaaaaaa tgagcagtaa gacaagtcct atgttttttg ttatacttgg
     2401 gaagagaaag ctaaagcagg tgaaggaatg aaagtaaaag taaaaaaaag agcaagcaat
     2461 cgattgaaaa aaggatatcc actgatccaa aaagaagacc ttgctcatcc ccaaaaagaa
     2521 accacgcaat gggtggaatt agttgattcg caaaaccaat ttatcgcaaa aggatatcta
     2581 ggaaagcaga ataagggaat cggttgggta ttgagccagc agaacatccc atttgatcaa
     2641 tctttttttg aagaattttt tgtgaagtca aaagaaaaaa gaactttctt tttttcagat
     2701 gattctacta ccgcttttcg tatattcaat ggagaaggag acgggatcgg cggtctgatt
     2761 gttgattatt atgcaggtta tgctgttttt tcttggtata acgaaacgtt atatgcacat
     2821 cgtgaattat tgattcaagc ttttcgtgaa atctacccgg aaatcgtagg aggctatgag
     2881 aaaattcgat ttgaatcagt aaatctgcct gagagccagt tcatttacgg aaaagaggca
     2941 ccggaaccct tgatcgtaaa agaaaacgga gtaaaatttg ccgtttattt aaatgaagga
     3001 ttaatgactg ggatcttttt agaccaaaaa gaagtacggg gatcattagc agaaggtttc
     3061 gcttctggga aaacagtttt gaacatgttt agttataccg gcgccttttc tgttgctgcc
     3121 gcaatgggag gggcaatcga aacaacaagt gtcgatctag caaaacgcag tttaaaaaaa
     3181 acacaggaac agtttgaagt gaatggtttg gatgtcgatc agcaaaaaat cattgttatg
     3241 gacgtattcg agtatttcaa atacgccaaa agaaaacaat ttttatatga catgattgta
     3301 ttggatccac caagttttgc cagaaataag aaaaaagtct ttcgcgtagc aaaagattat
     3361 ggggaactgg tcaaggatag tctggatatt ttagcagaag acgggatact tattgcgtct
     3421 acaaatgctg cgaatgtctc gatagaacaa ttccaaacaa tgattgaaga ggaattccat
     3481 gccaaaaatg tttcttttga acaacttgct ttatatcgtc tgccaaaaga tttccagacg
     3541 acggatacct ttttagaagg caattatctg aaagtgtttg tttatcaaat taaaaataac
     3601 cattagaagg agcgatgcag aatggtttgg gtaaagggat tgaatatagg aagcggtaga
     3661 ccaaagattt gtgcgcctct tatcggggcc gtccgagagg aagtattacg tgaagcagtt
     3721 cttgcacgtg aagcaggggc cgatttagtc gaatggcgag tcgatcatta tcgtgaagtt
     3781 ttttcttttg atgaagtagc agaaacattg gttcttatcc atgagatgct tgatggactg
     3841 ccgttattat ttacgtttcg taccttagct gaaggcggag aacaagacat atcgatccgt
     3901 cagtatcgcg acctttatga acatgtgata cacacaggat tagtagatat ggtcgatatc
     3961 gagttgttca aagtagaaag tctaggaaaa agactgatag aggaaatcaa gtctttaaac
     4021 attcctttaa ttatcagtag tcatgatttt aaagaaacac cagcagaccc tgtcttgctt
     4081 taccgattga atgttatgga acattttgga gccgatatcg gaaaactggc agtaactccc
     4141 aataatgaac gagatgtttt gcggttgatg gagttgacta gacgggcaaa tgcttttgtc
     4201 tccatgccta ttattacgat gtccatggga aatcttggta aaatttctcg tctggctggc
     4261 ggaacgacgg gttccgttat gacatttggt tccttaagca gcgattctac ttctgctcca
     4321 ggacaattac cggtcaaagc attgaagcaa attattcaat tattaaatga accgttgtag
     4381 aacaagtttg aggtgatatt ttttggcaaa gaaaaaaata gtaaaaacga atgcaatccg
     4441 tatggtcgaa caaaaaaaga ttccctatac agagcacgaa tatgagtggg acgaaagcca
     4501 cctaagtgcg tcatcggtcg ctgaacagct tccagaaagc caatctcata tatttaaaac
     4561 actggttgct gtgggcaatg tgacggggcc tcttgttgct gtgataccgg gagaagccga
     4621 attgaatcta aaaaaattag caaaagtttc agggaataaa aaagtagaaa tgctccattt
     4681 aaaagatttg gaagcaacga ccggatacat acgtggtggc tgctcgccta taggtatgaa
     4741 aaaactattt cctacttatt tagatcaaat tgcagaaagc tatgaacaaa tcattgtctc
     4801 ggctggcaga agagggctac agatggagtt agcacctcaa gatatctgtg cattaacgag
     4861 cggacaattt gcagatataa aacaataaat catacgtata aaagaaagaa ggaggccggg
     4921 atgttgtttg tccagtctcc ttctttcttt tttatacatt atgctctttg cccggcattc
     4981 attcctgcta catgccctgt agcgaaagcc gctgtgatat taaagccgcc agtataacca
     5041 ttgacatcca gtaattctcc cgcaaaatac agaccatcaa tgattttact ctccaatgtt
     5101 ttaggataaa tttcctttag agaaacccct ccgccagtta caaatgattt ctcaatagga
     5161 aaagttttgt tgattgatag cttaaactct ttgcatagtt gaacaaaatc ttgaatttgt
     5221 ttttgagagg cttgttgtcc tgtcagatga tccatttcaa gccgctcaag aaagaaaact
     5281 aacaatcgct caggcaatat accatgccaa gcattgacca agttcttttt ggttgcttta
     5341 cttttttctg tcaatatatg aataagctct tgtttggttt gtgtagggaa acaatccaga
     5401 gaaagtgtca ctggttctcc cgttttctct aattctttat tgacaaaact tgaacaacgc
     5461 agtgcagccg gaccagaaat accgaaatgg gtgaaaagta aatccatcgt atgttcagtc
     5521 aatacacgac cttttttatt taaaacgcgt aaagtgatgt cttgtaaaga aagcccttga
     5581 agtgttttct cctgaatata cggttcatcc gatatcaagg gggactctgt cgcataaaga
     5641 ggcgtcaccg tgtgacccac tcgcttcacg atcttgtacc catctccagt agaaccagta
     5701 gatggataag tccgtccacc agttgttaag ataatggcag gagcatggaa ctcttcgaat
     5761 tccgtgcgta taccgtaaat tttatgttct ttgtggatca atttctctac tcgagtagag
     5821 aatagaagcg tcacatctag ttctttcaga cgattgagca atgcttcgat aatcgttttt
     5881 gatttatttg ttacaggaaa catccgtcca tgatcctctt cttttaaatg tacgccttgt
     5941 gattcaaaga agttcatgat atcgaaatta ttccattgcg caaacgtact atataaaaac
     6001 tttccatttc caggaatatg tgcaatcaaa tcatcaacag gacgattgtt cgtaacattg
     6061 caccgaccac cacctgtcat cagtagtttt tttcctgctt ttttgttttt ttcgatcaag
     6121 agtacgcgtg cgccttgttc agctgcactg atcgctgcca tcatcccgct tgttccagcg
     6181 ccgactacga tcacatcata cagtttttcc attccctcac ctcaaggaaa gtgtagcata
     6241 tctgaagaaa gaaaacagaa aaaatgtttt gagccaaaag agaaaatgag ctaaaatgag
     6301 ggaagataag caaaggagcg tggaacgatg acaaacgcaa cagaatatgt tcaagcaatt
     6361 caagaaaagc tacatcaaaa ggatcaaggg caagaagaat ttttacaagc aatcgatgaa
     6421 ttcatgccca cggttatgtc ttttttggac actcatcccg aatatatcga aaagaatatc
     6481 ttagaacttt taacggaacc agaaagagtt attcaatttc gagtgccttg gcaagatgat
     6541 gaaggaaact ggcgagtaaa tagagggtac cgtatccaat acaactcagc tatcggccct
     6601 tataaaggtg gattgcgctt ccatcctagt gtcaatctaa gtatcttgaa atttttggct
     6661 tttgaacaga ttttcaagaa tagtttaacc ggtctgccaa tcggtggagg aaaaggcgga
     6721 agtgacttcg atcctaaagg aaaatctgat aatgagatca tgcgtttttg tcaaagtttc
     6781 atgctggaat tgtcaaaaca tatcggccca tcgattgatg ttcctgcggg agatatcggt
     6841 gtaggagcta gagaaatcgg ctatttgttc ggcgaatata aacgattgaa aaaatatgat
     6901 actggtgtgt tgacaggtaa acctttggat ttttggggaa gtaagatacg tacggaagct
     6961 actggttatg gattagtgta ttatgtcaaa catctattga acgaagaaaa agattcattt
     7021 aatcaaaaaa cagtttttgt ttccggaagc gggaatgtag ccatttatgc aatcgaaaaa
     7081 gtgcaagagc taggcgggaa agttgttaca tgttcagatt ctagcgggta catctatgat
     7141 ccagaaggaa tagatgtgaa actattgaaa gaagtcaaag aaatcaatag acaacgtttg
     7201 acggaatacg caaaccaacg tccttctgct atttatcatg ctggagaatc tgtttggaca
     7261 ttgaaagaaa aagcggatat cgctttgcca tgtgctactc aaaatgaaat agacgaaagc
     7321 ttggccgaaa tcttagtaga aaatgggatc aaaatcgtag cagaaggcgc taatatgcca
     7381 tgtacagtaa aagctgtttc tgttcttcat gaagcaggcg tgtggtattg tccaggaaaa
     7441 gctgctaatg ctggaggagt agcagtatct gctttagaaa tgagtcagaa cgcccagcga
     7501 ttgacttggg aaagagagca agtggatgag cagctggatc aaatcatgga aacgatttac
     7561 catacgtgtc gccaaacagc agccgagtac ggcgacgaaa aaaatctgct tcttggagca
     7621 aatgttgctg gatttgaaaa agttgccaaa gcaatggcag cagaaggttt agtttgaaaa
     7681 atgaaacttt cttggaaata ttgtcagcat tttgtttatt tgcttgaaaa ataataaaaa
     7741 aaaacgtaaa gtattacctg tagagtaaac ctataaggag gagaacaaat ggcacacatt
     7801 cattttgact attcaaaagt agcaccgttt gtcaacgaac aagagttagg gtacatgcaa
     7861 agccaagtaa cagcagccca caacgaatta cgggaaggta ctggcgcagg aagcgacttc
     7921 cgcggctgga tcgatttacc aacgaactat gacaaagaag aatttgcacg tatcaaagaa
     7981 gcagctaaaa aaatccaatc tgattctgaa gtattagttg ttatcggtat cggtggttct
     8041 tatttaggcg ctcgtgcagc gatcgacttc ttgaatcaca cattcttcaa tttattagat
     8101 agcaacacaa gaaaagcacc acaaatcttc tttgccggaa attcaatcag ctcaacatat
     8161 attgctgact tgatcgaagt aatcggtgat cgcgactttt cagtaaacgt tatttcaaaa
     8221 tctggaacaa ctactgaacc agcgattgcg ttccgtgtat tcaaagagct tcttgttaag
     8281 aaatatggac aagaagaagc aaacaaacgt atctacgcta caacagataa agcaaaaggt
     8341 gcagttaaag tagaagcaga tgcagaaggt tgggaaactt tcgtgattcc tgatgacatc
     8401 ggcggacgtt tctctgtatt aactgctgtt ggtttgttac caatcgctgt tagtggtgca
     8461 gatatcgatg cattgatgca aggtgccgct gatgcaagca aagcatactc aagcgacaaa
     8521 ctagaagaaa acgaagctta ccaatacgca gcaatgcgca acattcttta ccgtaaaggc
     8581 aaagtaactg agttgttgat caactatgaa ccaggaatgc aatacttctc agaatggtgg
     8641 aaacaattgt atggtgaatc tgaaggaaaa gaccaaaaag gcatctatcc ttcaagcgca
     8701 aacttctcaa ctgatttgca ctctttagga caattcatcc aagaaggacg tcgcaatatt
     8761 tttgaaacag ttgtgaaggt tgaaaaacct cgtaaatcaa tcacaattcc tgaacaagca
     8821 gaagatttag acggtctagg ctacttgcaa ggaaaagaag tggacttcgt aaatacaaaa
     8881 gcatttgaag gaacattgct tgctcataca gacggtgacg tgcctaactt gctagtcaaa
     8941 attccagaaa tggatgctta tacattgggt tatacaatgt acttctttga aattgctgta
     9001 ggtatttcag gttacttgaa tggaatcaac ccattcgacc aaccaggtgt agaagcttac
     9061 aagaaaaaca tgttcgcact tctaggcaaa ccgggctttg aagatcttgc taaagaattg
     9121 aacgaacgcc tgtaagataa gggtttttcg ctagatttaa ataatcagtg atagaaacat
     9181 gttcgcttta aaatgaaaac tggtacccat ttaggtactc aaacatactg catcgtttat
     9241 tcagaataag gggctgtgac aagacgtttg tcacagtccc ttgtttgtat agaaatcgat
     9301 tgattgcctt gctctttagt ttgttttagg actttaagaa cagtgaggct gacttcgaag
     9361 gttaattctg tttttttgtt ttctagaatc agtaagcaaa aaagcactca cttcgagtgc
     9421 ttttttgcga tatattctta gcttaagata ggcctaattt ttcttttaca gatgagggta
     9481 ccttatcgct ggtaattact tttttctcta tgatccgctt ttcgcttgct ttcaactgca
     9541 agatcgttcc ttcggtgtaa gcagaaccat tggcagagtc accagaagta atgacatcga
     9601 aatctaactg tcttttttca ccgttttcag cataagcatc tacgttgtat ttaaaacctc
     9661 ttccaattac ttccccatta tctgctttga tatcagtttc tgcaggcatt ggagctttga
     9721 ctaccgcata ataatcttta cctacataag tagactgata gtagtcccaa cctttccatc
     9781 ctataaaagc aatcaatatg ataacgatca accctaaaat ttttttcatg aaagatctcc
     9841 ttttttattt ttattatatt aaatattata cagataataa cggaatatta tcatcgaaac
     9901 agctaacaaa attgtcataa aaaacgagat ggttgatatt agaacttgtg tttttgttta
     9961 ggtctagaga taaagagaga caatttccaa atatatgtaa tgaatacaaa aagacgtttg
    10021 tcgcggatta ccgttacaaa cgtcttttat tgattttccg agatctcatc agtcgccatt
    10081 tggaatggtt cactccttat ctagattcgt ttaatgctcg gactgcttgt tcgattgtaa
    10141 taccaaacgc aacgttattt tcgttttgtg catcaatcgc cataaaacgg ttagaagttg
    10201 tatcaaaagc tacgcggtat tgcatatttg tttttgtaaa cgtcataaaa ttcatctcct
    10261 ttgtaatgta atttagttct tgaaagtttc ctttaaactt tcgaacttat accaagttta
    10321 gcatcgtacg ttttttgatg caattaaaaa gcatttatca ttttccttat ttattttttc
    10381 ttaaatggtt tagctatttt cttttaatcc gataagtagc ccaatcatca aggttacaaa
    10441 tactattgct tgaatataaa tcatatgctc acctctttat aaataactta gcaatataaa
    10501 gaaaaaaacg cacgaacaac ataggaatat aaacaaacgt ttttgtcaca acgtctaaga
    10561 tcgtgttaaa aaatagttat ctaaaaagca gaaagatact caaaataaaa aataaaaaaa
    10621 tgaataaaaa cgttttcaaa tacaaggtaa tttgttatta taaaataaag aaaaaacaaa
    10681 ataaaaataa agaaaagagg gaatgaaatg gtaaaagcag aagtaggaag atcttatata
    10741 tgcaaaccga tcggagtatc tcatgaacta atcggctgta ttgaacgtac atatatcaac
    10801 acggctgtcg tgtatgttga aagttatgac caacgagact atcaacttat caatgaaagc
    10861 aagtatcgca tgctcgtaaa attctgtgat attagcgcac ctactgaatt ggtttcttaa
    10921 acagtatttt tgagaattcg caagaactcc cttataatat aaataaagac agaagggagc
    10981 gagaagatat gccaaaaaga aaaagttcag ggaaaatggg aattattctt gcagtgatct
    11041 ctgcaattcc tgctatttta gctattgttc gtgcgatgaa ggaatcaaga gaaagttaag
    11101 cacacattat gagcgtcaaa caaaaaacgc atatacctgc ggtggcaggt tatgcgtttt
    11161 ttgttgtata aagacttttt tcattaacga tttttgatta gccgactccc aaaacaaaat
    11221 ttagcagttt atctgaataa gtgatttctt catctgtttg tttcacactt tcatttagta
    11281 gtcccatctc atcggttatg ataccatcca caccataaaa catcatgcga ctcatggcat
    11341 ctgaatcgtt gattgtccat acatatactt cttttccgtc ttggtgggca gaattaatga
    11401 agttacggtt gatcgtacta tattccattg tcagaaaatc agcaggcgtc acagggggcc
    11461 caacaatatt gaaaggtaag atgtagccca cataaaagtt tggttctgct tcttttaaat
    11521 ctgaaacggt ttggtacgtc aaactttgca aaatatgatg gttctctaag ataactttgc
    11581 ggtatttatg gacaaatcgt tcgacaaggt catccgaatc ttttttagag gtcttgatct
    11641 caataagtaa tttttggttt agcttatgtg ctttttccaa ataagaatca aaagaacaaa
    11701 caggggcttg cactccgttt tcagtaactg taagatttgt caattctttc aatgtaagat
    11761 cctgtggtgt tccatttacc cctgttaagt gacgaagatt tgcatcatgc atcactacga
    11821 aatgaccatc ttttgtttcc tgaacatcca tctctacata atcaggatga tagtctctgc
    11881 ttgttttttc aagtgcttct aaagtatttt gcgccccatt ttgggtactc acacctctgt
    11941 gagagacagt cactggtttt gtctgaacag ctgaagtcag ataatccata ttgtaaagac
    12001 agacgccaat accgaaaaaa actgcaaaaa gagtcaaacc agtgtttttc agcgcagaga
    12061 aacgcaagtt gggggcttgt gggataaacc acttagggat ctcaggcaag aagccttcgt
    12121 catccatgaa atcaacaatg atataaaaaa tccctacggt agacatcacg atattgaata
    12181 ataaaatccc ttgtaaaagc gtcatagcaa acacagcgct gatcaatgca tagtctggga
    12241 aaaattgttc aaccatactt tgtgccaaaa taacaacgat atatcctaaa gaagaaagga
    12301 gtaaaatcgt accgccaatc acaataaatt ggcccgtgat ggccaaaaga cgcgatttgg
    12361 tcaatgacca gctttcccga atggctgctc gaaaagaacg atctcgtaga atcatttccg
    12421 gtaaagcaaa aatcagtcga atcccaatat agccaaggaa aatataaacg agtaaaaagg
    12481 aactgacgat gatccaacga ttagcaaaaa taaaatccat aatgaaagcg gggattttta
    12541 tttttgacag tagatcagaa ttaaaactta atccgctgat cggtagaatc aataaaaaat
    12601 aagcaaggaa aaacaaaaaa gtaatgggtc tcactttctt cagctgaagt atcgtcaagt
    12661 gtaagagttg cttcaaagag attggttctt tctttttaat aaaaaaaaca ctcatcaaaa
    12721 gaaaagtaaa ttcgaaataa actaacagta aaatcgtcat caaaactacg attaacgaga
    12781 gtagaacccc aggatgttga gaaaaaattg aaggaatatt gtcataagac aaatagtcaa
    12841 ttgcccctcg gtgtaaaata aaacgggtcg tactgctcaa taagggtaaa caaataaata
    12901 aaataaagcc atgcatcagc aagacatcac ggaaataagc ttgtgttcct tttaaaaagt
    12961 cccaagcatt acctaagcta cgtttcaaat aattcatcct atcacctgct cttcacattg
    13021 tagcgcaaat ctaatgaaaa aggaaagggt gcagtgtgtt ttgcagaccc tttcccagat
    13081 ttaa
//
LOCUS       DAYNVV010000071        13052 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.074, whole genome shotgun sequence.
ACCESSION   DAYNVV010000071 DAYNVV010000000
VERSION     DAYNVV010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13052
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.074"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(28..2067)
                     /locus_tag="ACGXWR_002362"
     CDS             complement(28..2067)
                     /locus_tag="ACGXWR_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFK0803886.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKIAFDSLGGKAASTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFINNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(2125..2682)
                     /locus_tag="ACGXWR_002363"
                     /pseudo
     CDS             complement(2125..2682)
                     /locus_tag="ACGXWR_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     regulatory      complement(2830..2996)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            complement(3221..3427)
                     /locus_tag="ACGXWR_002364"
     CDS             complement(3221..3427)
                     /locus_tag="ACGXWR_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803887.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(3443..4057)
                     /locus_tag="ACGXWR_002365"
     CDS             complement(3443..4057)
                     /locus_tag="ACGXWR_002365"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HFK0803888.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(4204..4887)
                     /locus_tag="ACGXWR_002366"
     CDS             complement(4204..4887)
                     /locus_tag="ACGXWR_002366"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFK0803889.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(4996..5454)
                     /locus_tag="ACGXWR_002367"
     CDS             complement(4996..5454)
                     /locus_tag="ACGXWR_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HFK0803890.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(5538..7301)
                     /locus_tag="ACGXWR_002368"
     CDS             complement(5538..7301)
                     /locus_tag="ACGXWR_002368"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HFK0803891.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(7522..8982)
                     /locus_tag="ACGXWR_002369"
     CDS             complement(7522..8982)
                     /locus_tag="ACGXWR_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803892.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(9190..10116)
                     /gene="glsA"
                     /locus_tag="ACGXWR_002370"
     CDS             complement(9190..10116)
                     /gene="glsA"
                     /locus_tag="ACGXWR_002370"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HFK0803893.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(10139..11566)
                     /locus_tag="ACGXWR_002371"
     CDS             complement(10139..11566)
                     /locus_tag="ACGXWR_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFK0803894.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(11597..12811)
                     /locus_tag="ACGXWR_002372"
     CDS             complement(11597..12811)
                     /locus_tag="ACGXWR_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HFK0803895.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
BASE COUNT         3751 a         2720 c         2177 g         4404 t
ORIGIN      
        1 cttttactgt acttaaaaag caatttttta ttgataattt tggttgaggt attgcaatag
       61 ttccgatgct cgtttggttg ctgaatcatc atcttcttta ttttccaaca tgctgaccat
      121 catataacct tggttatcaa gattgaaagc aaacaagaaa ctgttctctt gcccctttac
      181 atcctgtttt tctttgattt ccgctgtacc agttttcgct gccaacggaa tccctaaagc
      241 agaaagagaa tgtgctgtac catttacatc ttgcacaact tctctcagat ctggcacgat
      301 cgtttgtact gctgtttcgc tgatgacatt cttcttatct tttgtctctt tatctgcaat
      361 caatttagga tagacaagtg tgccattgtt gataaaaaca gaatacattg ctgcttgctg
      421 gataggagta attagaagtt cgccctgtcc atatccagta tcagctagca agatatctga
      481 gttaaagcta tcttcattag aaatttgtgc tggattcata ctaattggca aatcaaggtc
      541 ttcaccaaaa atgaatttat ctaagcctgt acgaaatttt ttctcaccca ttttcaacgt
      601 ttcttgtgcc gcatatatat tatcggaata gatcaaagca gtttttaagt ctacttgtga
      661 tacatcacta ctgacacgcg ttgttttaaa agatccccaa gaactgtctt tttgccattt
      721 aagcccgttg atcgtcaaca cttcatttgg atcgatagtg ccgttgtcga gaccgattgc
      781 tgctgtaatc attttaaacg tagatccagg agcataacct gtcgcaaatc ggctgatgaa
      841 tggatgttca ggattttctt cataagcttt gtaatcttct tgtgagatcc cgtttgtcat
      901 tttgtttgga tcatagcttg gagagctagc aagcgcaaga agatcaccgg tttttggcgt
      961 tgtcgcaaca gttgatgcag cttttcctcc tagactgtca aaagctattt tttgtgcctt
     1021 cgcatcgatt gtcaatttga tatctttgcc attttgaact tcatgttcga tcagaacttt
     1081 tttctctaca ccgtctgcat ctgtaatgct taatttccca cctgttgtcc cacgaagatc
     1141 cttatcaaaa gccatctcca aacctgagcg accgattttt ccattactgc ttaattctgg
     1201 attcttatca atatcttctg ctgtgatatc tcccacgtaa ccaatcagct gagcagctgc
     1261 ttcacccaaa ggataatatc tgccgtctac ttcttgaatg gtagctccag ctggaagttc
     1321 tggcgttgct ccatcaatga ttttcaatgg gacaaagtaa tcgggttgta cccagctttg
     1381 tgaaatcgcc tgattgatag catcttctgt taagtcgaag gaggaagcaa tcgctttgat
     1441 attggctgtt ttttcgcctc catctccaag tttacttgga acgactccta attgttttag
     1501 tttgcctgtt gttgctaatg gttcaccatt tcgatctata atattccctc ttgctgcttc
     1561 ttgtgtggtc aggcttactt tgtcatttcc ttccatttct ggaaaaacca agttgggttg
     1621 ccagttgatc gtggtttgac catcatttct gtctaatgtt cctttataag aaagatcttt
     1681 caattcacct aatgaggtat tcatctttgc tttatatgaa aaactgtaag tagaatcgtc
     1741 ttttttatct acttttagat tcgatatctg aagtcctttg acatcagcag caccgtatat
     1801 attctggtat ttatctaaga tctctttttc agataatgca cttttatttg ccgccttttt
     1861 tgatgtcatt tctgcagctt tgttataatc tcccttgttc aaagcttgga caaattgctc
     1921 aactgtcttt tctccagctt ctactgcttg ggtttcttga tagtgctggt agtaaaaata
     1981 accgccaccc gcagctgcta ttaagatcac tgcgccggca atataagcgc ctgttcgatt
     2041 tttgccgtgc ttgtcacttc ttttcatttt ttcctccttc tcttgcttgt cattccttta
     2101 tttcactatt tatacctgtt tattctaaca tatgtctttg aggaaatcca taccacaatc
     2161 cagaagcaca ctttctggaa ggttcgtttg gatactacca agtaatttcc caaccgcttt
     2221 gggtagcttg aatattgaag ttacgtcttt cagctgctga gagatagctt tgatcacttg
     2281 ctgctgcctt ctgatcctcc cgaagtctcc ttctttgtct tcccgaaatc gagcatactg
     2341 gagtaaagta ttaccatcca tcacttgctc tcctttgttt atatatacgc catctaaatc
     2401 tagagatttt tctgcatcga tcttgactcc accaggaaac agttcattaa cgcaatcgat
     2461 aaaatcttga aatgtgatac ttgcataata gggagcttca aatttgaaat tttcctttaa
     2521 tgtttgattt aataaatcaa ctcccccata agagtaagct gcatttatct tattcattcc
     2581 gtaacctgga atatcgacat atgaatctct catgatagag atcagttttg cttgttgtgt
     2641 tttctggttg tattgtgcaa ccagaagtga atccgagcga cctccaccaa tcgatctttt
     2701 ttcaccgcat ctcctcctca cacagcaatc cacttgtcag gtgaggagcg agtttgtctc
     2761 atcaaataag tcagtcacaa aaatataaag aaaaggtcag aaaccttttc gaacaagaat
     2821 tctgacctag catcatctca tcgtccgagt tttagcacta tacaacgtaa agaaaacatt
     2881 cttagctatt ggaaaaagcc ttaatccaac agtttctgtt ttacccattg gcgactttcg
     2941 acgtttctgg gcaacagcct atgtttgtat aggagcctca cctaacaagg ttattactat
     3001 attctattta cgagttcatg atagactttt cctaatgatt aggcaatgga atttgaaatg
     3061 aaatagtgaa atttaacaat ctttaatatt ttttagaaaa aaataacaaa taagttgaaa
     3121 gaatcccgtt gcaaattctt tcagttgcac caggattctt tgataatttt ttagttttat
     3181 gtgttttttt atatgttttt tcacttttcg gaataaatat ttatttgtta aagtaattaa
     3241 acaatccgct aatcgtttga tctggcattt ctatttcctt accatctaaa gtaacagtag
     3301 taacgacaaa atggtcttgc aatggcggaa cttctaagta ctgcccttgc agaaaatcat
     3361 tcactgtttc atattctttt ttcatttctt ttgaatctgt cgatggttta tagcttattt
     3421 ttaacataac tagtgctcct ttttattcgg gacgtgcaat cgtgaaaatt tctcctattg
     3481 ctgcataatc atttcctgcc aaacggctta cagcattcaa ttttcttgga tcgatccttc
     3541 ctgtcttatc atcatagact gtttcattta aatgatattt ctgtacttct agcaaaaata
     3601 aatcagctgt tactttattt ttattccgta tctcgacatg ttcatataag gatgtttcaa
     3661 aacgaacttt tgcttctgtc aatgctggta ctgaaatgat tactgaatca gttaaagtca
     3721 agtcagtcag gtacagttcg ctttcctcat taggcagatt ggctgctgtt ttatttactt
     3781 cttctacgtt gtcctcatca aggatatgga taacagcttc tcttgtctca agaatattct
     3841 ttgctgtgtc ttttactgca tcttgttttc tctggatcgc caaggataag atgggtcgat
     3901 tcgaactgac gatattgaag taactgaagg gtgcgatatt cactatatct tttgctgatt
     3961 tagtcgttac tactgctact ggtctaggga tgactgaacc aatcagcaac ttgtaatttt
     4021 cacgttctgt caattctgaa ggactccgtt caaacatggt ttcgccttct ttctataaaa
     4081 ttcgttaaaa agcagatctt gaagacaaaa tgaaaagtaa tgcttttttc atcttcttag
     4141 aatctgcttt aaactatcta tcaatttttc ttttttgtca agaatctgtg ccgtgcgtgt
     4201 tttttagtta tttgctttac ttgcggcttc gacatatctt ttagtgatca attgcggacg
     4261 ggtgataata gatccaacta cgactgaaaa agcacctaat tcatatgctt tctctacttg
     4321 ttcaggagag tcagtatgtc cttccataat tactgggata tcgacttgtt ctatgatttg
     4381 attcaataaa tcaaaatcag gtgtctgcgt ctttcgtgaa tattctgtat agcctgctaa
     4441 agtcgtagac aaaagatcaa aaccatcttc ttgcgcttga agcgcttcct caaaagtcga
     4501 aatatctgcc atagctaacc gaccgtgttc gtgaatcatt tggacaagtt cagcagttgt
     4561 tttttctgtc ggacgtttac gagaagttgc atccagtgca atgatttctg cttgcgtctc
     4621 caaaagttct tccacttctt tttctgtcgc agtaataaac acttctgacc catcgtaatc
     4681 tcttttgata atccctatta ccggtaaatc aacgattcgc ttgatttcat tgatatcttc
     4741 tgtcgtattt gctcgaatac caactgctcc gccttctttt gcagccaaag ccattctccc
     4801 cataataaaa gaactgtgta gcggctcgtt ttccaaagct tgacaagaaa cgacgactcc
     4861 gcctttgatt tgttccagtg tatccacaat atctcctcca gtaatgttat ataaaaatac
     4921 agcttcatat aaaaatgtaa cccttttcta ttcaggagac aataatgagc tatttctttc
     4981 agcagacctt tcttactaaa agaaaattac ttcaaattct tcgtatacga ccagcttctc
     5041 ttctgtaaat tctatgttca acgcttcttt ataagcatgt ttaaaaaact cagcatggac
     5101 tttccgccaa taagctaatg tccgatcccc ttctccttct ttccaagcat gctctttcgt
     5161 gacttcacta aaaggcaaga tggtcacatt tatatttttg atgatacaaa ctggttcatt
     5221 ttttccattc aggaccacgt ctaattgacc aacttttggt aaaggctcat tctcttgttt
     5281 atacagatcg taaccacttg atgtaccagt ctttatcttt tttacaacta gttcgctcaa
     5341 ctcgtctgcc attttttctg tatccccaaa tgaaaagaaa cctaattttt ctgattgata
     5401 actaggatat ttttcttgga actttttgac atattcttct acttgctgat acataacatc
     5461 cacccctttg ctttttataa tgaaaaaacc atccagatac tagtataaac aattatctgg
     5521 atggtgagca taatgaatta ttgaatattc aagacacgca gactatcttc aacgatttgt
     5581 tttggtgtta aatgataacg ttcataaagc tgccctacag gaacgctatc cgtgaattct
     5641 ttctctgcac caaaatttaa tacgttcatt gaagaatcac cataataacg actgatattt
     5701 tcgccaaatc ctcctgacaa actaccatct tctaatgtga tgactaattc gtgtgtttct
     5761 tttaatttat ctaatgtttc tacgtcattt tctgtgatcg ttcctggatt gatcaacgtt
     5821 gcttcgattc ctttttttct aaaagctttt actgtttctt ttcctaattc aagaaaaccg
     5881 cctaaagcta aaattgctac ttttcctcca ttatttactg tttgataggc tggaatacta
     5941 taatcatttg cgatagctgt accatgttct acaccatgtg taggaattcg gattgctaca
     6001 ggctgcgctg tttgttcgaa cgcccaatct agcatagaga tcatatcctc ttttgttgct
     6061 ggagcaagat atttgatgtt cgggatactt gataagtaag gaatgtcaaa tgttccttgg
     6121 tgtgttcggt cactagctga gatcgttccg ccaccgacta aaataatcac tggattctcg
     6181 ttgatcgcta aatcatgtga taattgatca tatgcccgtt gcaagaaagt acttgattgg
     6241 aagacgactg gacgtactcc ctgagaagcc aaagcagaag cgaaagtgat agagtgctgt
     6301 tcagcgatcc ccacgtcaaa ataatgatct ggatgttttt cttggaatgt tttcagtcca
     6361 aaggcgcctg gtatcgctgc attgactgcg gcaataggag ctgtacttgt ttgcattttc
     6421 ttatccaaat aatccatgat gatcatatta aatgtttctc cagaagttac ttgctttgcc
     6481 tccccggtgg acagatcaaa tggtacatgc caatgatatt tcattttatt atcgattgcc
     6541 ggctgataac cgcgaccttt ttccgtatgg acgtgaagta caatcggatg atcaatatct
     6601 tttacttctt caaataaacg gatcaccgtt tccagatcgt ttccattatc cacgtaacga
     6661 taatcaaatc ccattgcttt aaataggtta ttgctgcttt taccgttggt ttgacgaagc
     6721 tcagctaagt ttttatataa actgccatga ttctcatcaa tagacatctc attatcgttt
     6781 actaatacga ttagattgga ttgtaaaaca ccaccattgt tcaatccttc aaaagctaag
     6841 ccaccactta gggagccgtc accgataaat gctaccacat ttcctgattc tttcttcaga
     6901 tctctcgctt tagctaaacc tgttgctaag ctgatagatg tagatgtgtg ccccactgta
     6961 aaatagtcat gtttactttc atgttggttg gaatatccgc tcacttcacg gtaatgtcct
     7021 ttttcaaaac cattttttcg accagttaaa agcttatgac cataagactg atgggaaaca
     7081 tcccaaacga ttttatcctt tggtgaatca aatacataat gaaacgcaat cgttaattct
     7141 actacaccta gattcggacc aacgtgccca cctacatcgc tgtccttttg caagattttt
     7201 tggcgcatct cttctgccaa ctgtttcatt tcctcaacag ataatttttt gacatctgcg
     7261 gggctattga ttgcatccaa tacatgtaat actgtactca taatacattc tctcctccgt
     7321 actatcttct tttaatgaaa atagatttgt tacactttat ctattctact acttagagtt
     7381 gactctaagt caatagcatt ttaaaaaaat ttcagagaaa gcttgttata taagtagatc
     7441 ttcgcacgaa tcaggactca aataaaaacc ttctacagac aattaaaaag ctttgtagaa
     7501 ggtctcctaa ttaaggtctc atcaagaaat atgttttttt aataggtgaa gttcctgagc
     7561 aatatgatac aaatggatgt ttgcaccttt taatgagatt ggatagatct ttgtcttttc
     7621 agtttctaat ccattttgat agctagcagc atcgcacaaa accactcttt ttttcgcaca
     7681 tagacattca tcaggcaatt cttctaatga acgaaataaa ataggattta tttcagcgat
     7741 gccttcttcc gcatacaaat gaaattgggt tcgataaaaa aattgtttga ctgaactttc
     7801 tgaaacaaca aaaatttcta tttcctgtct ccccgcttgt tcactgttga tcaaagaaag
     7861 acttttgacg aattttcgaa tgaaattttc attccatctt agttggattt gatttttctt
     7921 tttccactct tccaatattt ctacaatttt tccgtacaga agttgttctt tttctgatag
     7981 aagatagatc ctttccggta aaaatacttg tccatctgcc cacaacgtac ggacaaattg
     8041 taaaaaggat tgcttgaaaa taaaattttc tgcatcgtcg atttcagcga tactaataat
     8101 ctgtaaaatc aattcattca gtgataggtc attgagaaca aaatttttat aaacaacttc
     8161 gaaatctttt cttaacagct ccatgttctc attggtataa tttctactgt tgaacaaaga
     8221 aaaaatataa tagacatctt cttcttgtaa gtctagaatt cctttttgct cttccaatcc
     8281 ttgacagact aattgaaata acggcttcgt ttctgcgctt ttcttatctt cttctttcag
     8341 tccaagggga aatgcctttc ttccgattgc gatctctatt cctcgtatga taaaggactt
     8401 ttcatcttcc gaatatcttc ttttaaaaaa atgagtctct acataatcaa tcaactcgtt
     8461 acaagcttct tctacatacg gatttttatt ttcatagcct tcccaattga cataacgtac
     8521 taaagctagc aagatgttcc gcgagtcaaa ttctgggata atgatttctt tatttttcaa
     8581 ataatcattt tctttaaaaa aatccaatac gatttttttg attgtatata ctttgctcaa
     8641 agaaataaat tcaagatcag ccagttctgt actcgtgaat ataccattaa aataataact
     8701 taaaaacttt aaaaaataag attgaccgta cagaaactgt gtgagctcag aaagagcaat
     8761 accatgtttg aatacgagtt tatacttatg cttctctctt acttgttctt ttatacaata
     8821 ttctagacac tcggctagac tttctagatc gtgaaggatc gttggtgtag tcacccttag
     8881 agaaatagct gtttgttcga tgtctatttc ttggaattca aataattgtt cacacagata
     8941 cacttttcta aatatatttc gctcgatgta attttccagc attcctgata cacgcctcca
     9001 gtttttctta tgattttatt taatcatatc tgtaaatcgt atttttgttt cctttttatt
     9061 tagaaaagcc ctttcaaaaa ccaataaaaa aagaaactgg gacaaaagtc aaacaagctc
     9121 acaatttcag cctcattgta ggtagctttg agccgtttgg acttttaccc cagcctcttt
     9181 caagaatggt tattcaaaga tgtcagcgtc tagttctttg actacatctt tcaacaattg
     9241 gataccagct gcgctgttac caaatggatc tagtgccggg ctgaagacac ctatgccgta
     9301 acgatttggc acagctgcca tcaacccgcc gcctacaccg ctttttgcag gtacaccaac
     9361 atggacggaa aactctcctg attcatcata caaaccagca gttgtcataa ttgatttgac
     9421 gattgtagca ctttcttcag taatgatttg tttgccattc caaggagcaa ttcctttatt
     9481 tgccagcaca gcagctaatt ttgctatgcc tgtagcggtg acattgaggg agcattgtct
     9541 gaaataagca tcgagtatct ccggtacgtc tccttcgatc atttgattac ctttcatata
     9601 gtaagcaaga gagcgattga tatcacctgt tcttgattca gaatgataga tttcttcatt
     9661 caatgtgata ttaggatcat cacagatctc tttcataaat gacaagattc gctcaaattt
     9721 ttcatctgca tctttaccgg caatcaacga ggttgttgca atcgctcctg cattaacaaa
     9781 aggattcatt ggatgtttgc gatgattgat ttccatattc atgatagaat tgaaggcaaa
     9841 accggttggt tccgtgttga ttgtttgaaa gactttttct attccgttgt ctttgattgc
     9901 taataacaat acgggaactt ttgacatgct ttcgatggca aagcgcacat cggcgtctcc
     9961 tccctcaatc agttgttttg tatccaaatc ataaatcgcc atacctaatt gtttgggatc
    10021 cacttcagct aatgctggaa tgtaatccgc cacttgtcct gtttgataat agtggaaatt
    10081 ttttccaatc aattgttcta attcttttac ttccatttga ataaccagct ttcatttttt
    10141 atttttctgc atgctggaat ttatgacggc atgcgtagat cgtaaatgga ataactaaga
    10201 cgataagata agaaacaatc agaatcgttt cataaatccc atgctgtcca gctgcgatac
    10261 tagcaggtgg aacaaatgag atacaaaaag caaaaagtga agtcaaaaga cctaaacaag
    10321 caacgattac ttttacaact tttccgcctg gaacctgata ggctctttca agactgtcat
    10381 ctttaaaaac cagcttcaaa tagcccgcga aaaacataaa gtacaacatc aggtagatta
    10441 caacagtcaa tgacatcgct gcaagaaatg aaagattatt ccccccgccg cttaatgtaa
    10501 agacggctgc ccagattgtt gcaacgatcc catttgcgat catcaaatga gcaggaacac
    10561 cgtgtgtgtt ttcttttgca aaatattcag gaagtaatcc ttcttctgct gctacgtgaa
    10621 gtgcttttga aggagaggtt acccaagaag caatttctcc gatgacacct aaacaaacaa
    10681 gaatcgcaag aattttcgca atccatgcaa gatttggatc aatgtgtctt aataggaatt
    10741 ctaacgattg aatcacccct gtattaagag acaaaccatg ttgaggtact gtagtagcga
    10801 cggtcaatcc gccaaaagta tctaaaatga ttgccagaat aaccaataca aacattgcta
    10861 atggataatc ctttttaggg ttttccattt catttgcatg actggcagat gtttctacgc
    10921 ccatatatgc taaaataaag gaaacaaaaa caaccagcgt aggcaatttc gaaaaatcag
    10981 gaatcaatgt tttcatagac agtatcgttt gtagtggagc gcctgaagcg acataatgga
    11041 tccctaagcc aaacaagact aatgctggca acaagatacc agctacaaaa ccgatccgag
    11101 caatcaatga agtgtatttg gttcctttta actgtgagag taaaatagcc cagaaaataa
    11161 tcaataggat tgccaatttc agatatttat tgttttgtat agcaccaata cccgttgcat
    11221 aggataatgc accagttaag aaatacagca tggtcaagta gccaactgtt atctcaaacc
    11281 attggaaaaa gattgcggca aaaccgaatc gttttcccaa tgtgcgactg acccaagtat
    11341 agacaccgcc tttttcccat cctttcaccg ttgccatctc tgctgcgcac aatgccacag
    11401 ggataaacca tagcaaaccg cctaataaca agaaaaatac taagctgaag cctgaggtcg
    11461 cgaatgtggg atattcatat aatgaaacga ccattgagat ggtcatagcc aaaaagccaa
    11521 agaacgttaa tttttttgca ggaattttcg ttttgctttg ttgcatgaat cttcctcttt
    11581 tctatttgaa tttgtttcaa ttgagtttgt tgccaaagaa gaaaaagtcc aatccttctt
    11641 cttgttcttc ttttgtagta gtgatcgttg taaagtgcat cgccgatttt aaaatcactg
    11701 ttgtcagcac ataggcatac acggcagtaa tgatgacacc aatcacttga atccctaaga
    11761 agtaccagct gcttggattc gttagtaaat ggctgttaga tgcaaagatc cctatcagaa
    11821 tcgtacctgt gaatccgccc atgccatgaa caccccacac atcaagtgca tcatcccatt
    11881 gtttcttttt acgaaaatca acagcagcat gacagacgat acccgcaatg atcccaatca
    11941 gcatggcact ttttgcttct acataaccgg cacaaggcgt aatggctgcc aatccagcaa
    12001 cggatcctgt tagtacgtcg acaaaatcaa agccatttcc ttttactttt gcaatgatca
    12061 gccaagtaat catcgcaaat gcaagagcga tgaatgttga accaaatgca ttgactgctt
    12121 gttcatctgc tcgaagtgca ccaccggaat taaaaccgaa ccagccaaac caaagcagtc
    12181 ctgtaccgat agcagctgcc ataagactgc tatgctgact tctttctcct aaaggaatct
    12241 ttctttgacc aagtgtgagg atacatgcta aagagccgaa tccagctgtc gtgtggatga
    12301 ctgctccacc agcgaaatct ctaaatccca tctgatccaa aaatccgcca ccccatatcc
    12361 agtggcaaac agggaaataa atcagcagat tccaaaaaat aacaagtata atatagcctt
    12421 ttaaattcaa tctccctgca aaagctcctg tcatcaaagg aacggtaatc acgataaaca
    12481 tcagttggta aagaaagaac attaaaaatg gaatcgttgc accatgaaac atgttgggga
    12541 agcttgtaac atgtctcatc aaaaagaaat ctgccgggtt tccaataaca ccgccgatat
    12601 cccgtccaaa ggccaatccg aatccaccaa atacccacat aatcgttgtt atcccaacgg
    12661 agagaaaaga ttgagacatg atcgttagta tattattctt ccgtgctaat ccgccgtaaa
    12721 aaaaagctag accaggagtc atcaggcaaa ccattgctgt acataaaatc atgaatgctg
    12781 tatctcctgt attgataggt aatgtattca tttttttcgc ctcctttcta cgattacgag
    12841 tataaaagaa ggtgtagttg tttttttctt ctgttttttt gaattaatac ttgcatttat
    12901 aaaagacaga caattaataa aagcttgatg tgttgtgctc tttttcgttt ttcacacaaa
    12961 taaagacaaa aaataaacgg tcttcttttt atagaaaacc gtttattttc gtcttttttt
    13021 atttttaaag atattttttc ataaggaata aa
//
LOCUS       DAYNVV010000072        12874 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.075, whole genome shotgun sequence.
ACCESSION   DAYNVV010000072 DAYNVV010000000
VERSION     DAYNVV010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12874
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.075"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            69..503
                     /locus_tag="ACGXWR_002373"
     CDS             69..503
                     /locus_tag="ACGXWR_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFK0803896.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(581..1114)
                     /locus_tag="ACGXWR_002374"
     CDS             complement(581..1114)
                     /locus_tag="ACGXWR_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HFK0803897.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(1208..2386)
                     /gene="mutY"
                     /locus_tag="ACGXWR_002375"
     CDS             complement(1208..2386)
                     /gene="mutY"
                     /locus_tag="ACGXWR_002375"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HFK0803898.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(2379..3176)
                     /gene="recX"
                     /locus_tag="ACGXWR_002376"
     CDS             complement(2379..3176)
                     /gene="recX"
                     /locus_tag="ACGXWR_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HFK0803899.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            3283..4665
                     /gene="rlmD"
                     /locus_tag="ACGXWR_002377"
     CDS             3283..4665
                     /gene="rlmD"
                     /locus_tag="ACGXWR_002377"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFK0803900.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(4839..5417)
                     /locus_tag="ACGXWR_002378"
     CDS             complement(4839..5417)
                     /locus_tag="ACGXWR_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HFK0803901.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            5739..6209
                     /locus_tag="ACGXWR_002379"
     CDS             5739..6209
                     /locus_tag="ACGXWR_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HFK0803902.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(6317..7543)
                     /locus_tag="ACGXWR_002380"
     CDS             complement(6317..7543)
                     /locus_tag="ACGXWR_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFK0803903.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(8297..8497)
                     /locus_tag="ACGXWR_002381"
     CDS             complement(8297..8497)
                     /locus_tag="ACGXWR_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFK0803904.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     LEVEFTIVEGARGPQAAEVTKL"
     gene            complement(8631..9239)
                     /locus_tag="ACGXWR_002382"
     CDS             complement(8631..9239)
                     /locus_tag="ACGXWR_002382"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HFK0803905.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(9324..9794)
                     /locus_tag="ACGXWR_002383"
     CDS             complement(9324..9794)
                     /locus_tag="ACGXWR_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HFK0803906.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(9842..10756)
                     /locus_tag="ACGXWR_002384"
     CDS             complement(9842..10756)
                     /locus_tag="ACGXWR_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFK0803907.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            10902..11705
                     /locus_tag="ACGXWR_002385"
     CDS             10902..11705
                     /locus_tag="ACGXWR_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HFK0803908.1"
                     /translation="MTTKQLIISSFIRFKDLKESRNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            11883..12830
                     /locus_tag="ACGXWR_002386"
     CDS             11883..12830
                     /locus_tag="ACGXWR_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HFK0803909.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
BASE COUNT         3914 a         2544 c         2122 g         4294 t
ORIGIN      
        1 gaaaacttgc catacttttt atttgtttta ttttccagta tactatacga aaggaaggtg
       61 gctagaccat gaaagttgta caaacaaaag atacaatgag caatatttac ttagatgctg
      121 tacggatcag gcatcaagtt tttgtagtcg aacagggtgt gcctttgtct cgagaaatag
      181 acaaagatga agcccattgt atccacttcg tcctgtactc agataaaaaa gaaccgcaag
      241 gaactgtacg tcttttgcct ttagaaaacg gaaaaatgaa attacagcgg atggcgattc
      301 tttctgaata cagacaccaa gggttaggaa aaatattgat tgaagaagca gaaaactttg
      361 ctaagaatca aggctataat acgattttat taggggcaca gtccacagct gaaacttttt
      421 acgaaaaact aggatataca gcttacggcg atccttttga agatgctggc atgcctcata
      481 tttatatgaa aaagacttta taaaaattta tttcgaaaaa agcaaaaaac agcaagcttt
      541 tgagaaaaat ctctcactgg cttactgttc ttttttgtgt ttacttacgc gacaattgct
      601 tgtaacggtt ataccaaata tcaatatagc cttccgagaa cgggccatct ccattattga
      661 tccagtcaac cagaatcttc acattttctt ttaggatgaa gtcaatatcg ttcgggtaat
      721 tcatcatttt gctgtgcatc tcatattcat cgacatccaa tagtcgtttc tcgccgtcag
      781 gaaatacctt gatatccaag tcatagtcga tatatttcaa ggcctcatcg tccagcaaaa
      841 aaggtgaagc tagattacaa taataggaaa cccccttttc tctgatcatt gctattacat
      901 tgaaccagta ttttttatga aaataaacaa tcgctggttc gcgcgttacc catcggcgtc
      961 catcagattc agtgactaat gtgtgatcat tcacgccgat catagagtgt tcgcttgttt
     1021 ttaataccat ggtatctcgc cacgttcgat gcaatttgcc gtcgtgcttg taactttgga
     1081 tcgtcacaaa ctctccttct tttggaactc ccatagcaac ccttccttaa gcagcatttt
     1141 gtgctttgtg tttgggtgtt cattacaccg acatcataat tattatatca ataaaaatga
     1201 gctttgccta gaaaggattc ctattgtttc gatttttctc taactgatct accagtttca
     1261 tttggacctt aggaaaaacg accgaatcaa atgcatcagg cttcaaccac ttcgaagttt
     1321 tgttctcggt aaattcttgt tctgctccct cggttgcccg tccgtaaaaa aggagaacat
     1381 gccatttcag atgactaaaa atatgagtaa cttctcctaa atgtcgtgtc tgccaaacaa
     1441 agagttcctg cttttcaaat gggagatttt gctcttcttc tgctactagg tcatcaaaca
     1501 gatcgatttc tggctttgtt tcccattctt ttttcaatcg ctcatactcc tcttgtgtca
     1561 cttccatcat tggaaatgtc cacatattcg ccagcaattt ttggctatct ctttcttcaa
     1621 aataatacgc tccagaatga ttttgaagag ctgcactgat ataataaacg tcttttggct
     1681 ttgctttttt tgtttttaca ggaaaactcg tttggattcc tcgtttgtta gctaaacaaa
     1741 aggcttggat cggacaagtc tcacactttg gagaagttgg tgtacagata gctgaaccta
     1801 gatccatcat tgcttggttg aattcacctg gatgcttttc atcaatgatt ttccgcatcg
     1861 cttcatcaaa gattttcctg ctagaagctt ttgcgatgtc tgcttcaatg caaaacaatc
     1921 tgctgactac tcgcatcacg ttgccgtcaa ctgcaggttc tggaagtcca aatgcgatac
     1981 ttgcaatcgc gcctgtcgta tatggtccta ttcccttcaa tgagctaatt tcttcaggcg
     2041 tttgcggcat ttccccatca aattctgaca tgatctgttt agcagcagct tggatgttcc
     2101 gggctcttga gtaataacca aggccctccc atgcttttaa aagcttttct tctggagcat
     2161 ttgctagctc ttcaattgta ggaaaccatt ccatgaaacg ataaaaataa tcgatcactg
     2221 tgtctactct ggtttgctga agcatgatct cagagatcca gatacgataa ggatcacgat
     2281 tatagcgcca aggcaggttt cttttttctt gttcatacca ttgaatgaac tgatcttgaa
     2341 attcttttgt ttctttatct gtccattttt cccattcttt attcactttc ctcttccttt
     2401 tccgtaatga atcgctggat catatccaaa tcaaatcctt tttgatataa gctttgcttt
     2461 acttttagat ttcttttttt aggttcaaac cttaaatttc ttcgccatag tttatctcct
     2521 tgtttgacta aataatcata ttctatttct tgatctgctt cttgcggaag atcagctatc
     2581 gcttgttgga tcacttcttg agaaaagcct ttcgtcatca atgtttgttg gatttttctc
     2641 aataattctt tttggctttt tccgtgattt tttccaaacg ctttttcggc tgtctgatgt
     2701 gcattttgaa cttggtcttc aaatgtatat tggctgagcg cttgttcaat gatttcaggt
     2761 ttcaaacctt tttgctgcat ctgctgcgct aatttctttg gtcctttgtc acttaagcgc
     2821 atattcgtgc gcacataact ttccccatag accaaatcat cgacaaggtc caattctttt
     2881 aagcgggcta cgattttatt tcgatcttct tgaaggattt ccttttcttt taagtatgtt
     2941 cggatttctt tttccgatcg caactgataa cttaagtaat tcattgctag gtgaaaaccg
     3001 aaatcagctc cgctactctt cttgatctct tggatagttt cttcgtctaa ttcccgtcct
     3061 tttaataatc gatagcgtac taatacatct tcagatactt gtaaagcttc tccttcagat
     3121 aaatctacgc gatagaaagg gcctttgcct ttactgattc tcgtaacggt taacataaac
     3181 atcctcctcg aacatatatt ctctatcata ccacagaaaa tccccgtaat caggtattat
     3241 atgttagaat aaaccacaga aaaaagaaaa agggagatac ttatggcaga aacaattgtc
     3301 aaaactggac aaacggttcc tttgaaaatc aagcgtttag gcataaatgg tgaaggaatc
     3361 ggttatttca aacggttgat catatttgtt ccatatgcac taccaaaaga agaagtacta
     3421 gtgaaaatca cgaaagcaac tcctcgctat gcagaaggag aattaataaa agtcaaaaaa
     3481 acaagcaaag atcgcgtagt ggcaccatgt cctgtttact atgaatgcgg tggctgtcaa
     3541 ttacaacact tagcttatca agctcaattg gattttaaaa aggatctgct tttgcaagca
     3601 ttggaaaaat tcaaaccagc aggctttcga tcttatcaac ttttgccgac gatcgggatg
     3661 gatgagcctt ggcattatag aaacaaagca caatttcagt tacgaaaaaa taagcagact
     3721 caaaaaattg aagctggttt atacgaagca aactctcatc agttagtccc tataacagac
     3781 tgcttggttc aagaacctcg aacacaaaaa gtaatgaata ctgttgttca actattgaat
     3841 aaatttgatg cacccatcta tgatgaacgg acaaacagtg gaatcttccg cacaatcatg
     3901 gttagaatcg gtgttaaaac tggggagtta caagttgttt ttattactcg cagtaaaaaa
     3961 ttcccgcaaa aaaacgcaat gatccgtgag atcaatgaac gactgcccga agttgtttca
     4021 atcatgcaaa atgtccaggc acaaaaaacg tctctcgtga tgggggatga aacgatccac
     4081 ttatggggaa aagaagccat tgaagaacaa atcaatgaag tgactttcga tctttctcct
     4141 cgtgccttct ttcaactcaa tcctcagcag accgaattgc tttatggcga aggaatcaaa
     4201 gcattagatg tccagcctaa tgaaacgatc gtggatgctt attgcggagt tgggacgatc
     4261 ggcttaagtg tagcaaaaca agccaaagaa gtacggggaa tggataccgt tcctcaagca
     4321 atcgctgatg caaaaaaaaa tgcggaaaga ttaggatatc acaacactcg atatgaagtc
     4381 gggacagcag agcaagttct gcctaaatgg ttgaatgaag gttttcagcc tgatggtatc
     4441 atcgtagatc caccacgtac gggtttggat aacgcattga tccaatcatt attgaaatac
     4501 cctccaaaaa aacttgttta tatctcctgt aatgtttcta cacttgccag agatctggtt
     4561 aatttaagta aaaagttcaa gattgaatat ttacagtccg tcgacatgtt tcctcagact
     4621 gcacgttgtg aagttgtcgt gaagatgacg agactcgctg actaaatgaa agaggttgtg
     4681 aaaaagtctg ccctgtatca agtaataaga acagccaaac aaaaatagct cttcatgttt
     4741 tatgaatact gtacttgtga ccgaagagtt aacaggagga cactatttat ttaaaaaaag
     4801 ggttgtgaca tagtttttgt cacagccctt tttgattatt attggatatt cacgtctatc
     4861 acttgataaa atgcatttgt cgtatcgctg atattccata ctgctaaaat cacattatat
     4921 ccttttcgat cctgcggaag tgtgatcgtt tggttgactg tttttggtgg aacagttgct
     4981 ttgtcgtcta tttttgtgat caattcaaaa tcactaaatt tcaaaggttg attaggattc
     5041 caagttggtt tggtaatgta gtaatcccaa gtacttgtcc gatgttgtgc tgttaaattc
     5101 caagtaatat ttaatgttcc tggattaacc atgtttttat gccatctgtt agatgtctgt
     5161 tcatctaaag gctcaaagcc gctgactcct gcactagcaa tttttccatc aatgaatgta
     5221 tttttggtag cttcgatact ttgcggttcc cattgtgctc ttccgacatt ttgatttaag
     5281 tttcctgctg ctgatgttcc taggtatgca cggcttcctg gagaagtaat ataaccatgc
     5341 gcaaaacctg gaatgctaaa accgaacaac cctaaactaa ctaacccaat aaacaataac
     5401 gtactaatct ttttcatgta gaaacctcct tcatttgata accacattgt aaacgcttta
     5461 ttgtattaac acaaacatta tgcttttata attttatgtt gaagtaaaaa aggtgaaaaa
     5521 agtaagatgc agattataac agaagtagac gagaaaagta caaatagaaa acatgagaat
     5581 caaatcatat gatctttttc aaaaacatca ttcatataaa caaatgttca actttttaat
     5641 aacaacaatt atcaattttt ttcttacttc acaaactaaa tacaggtctt gctgtgagcc
     5701 ttcatggtaa actaatatta tagaaaggag ttagtaaaat gaagatgata aaagatattc
     5761 gtttttgggt ttgtgttata ggaattgtca tattaggctt tttatcaggg ttgcttagcg
     5821 gaaatcccgg aaaatattac tattctttgc aacttccacc atttgcacca cctagctgga
     5881 tatttgggcc gatgtggacc ttactgtata tattgatggg tatttctctt tatttgttac
     5941 ttaatcacaa caacaaaaaa cagcgaaaca atcttgtcgg tctttttgtg attcagttca
     6001 tttttaattt tatatggtct gctctatttt ttaatttaag aaatattttc attgcagcaa
     6061 tcgatattac acttttagtt attttcttgt cagtgcttat gtatcagttg tggctgcatc
     6121 atcgcctggc aatgtggctc atgattcctt attatttatg ggtactattc gcaactctat
     6181 tgaattattc aatttatttt ttaaactaag cgctaaaaag agacgtcctg taatttaaca
     6241 catagaaaaa gtgccaccta agttagattt tttgtctaat ttaggtggca ctctttatta
     6301 accaaactat ttttttctag tacccacttg ttgttccata ctcattattc tggtcataac
     6361 cataaccatt ttgttcctgt ccagcgtaag gatcataact ttgagtatct tgacttggtg
     6421 tatagtactg acttgtatct tctgtttgct gataataggt attcggatct tggtactgat
     6481 catatgtgtt ttctgaatag gaagaataat cggtgtaccc ttcactattc gatccatcac
     6541 cgtttgtcga atcgccatct tccgaatcat caaagaacat cattgaagca ttctcatttt
     6601 tcaaattagg taatgtatcg cttgttttta tatttaattg tttcttcagt tcattttgga
     6661 tcgaaagaag atcatttttt cctaaaattt gatagtagat atcattgatc atttgtcctt
     6721 cgccttgcaa ctggtcttgt ttgattgttt caaacgccgg ggtgtagttc gtcgctacat
     6781 caagcatgtc atcccaatct aagtccgtcg tcacattgtt ctcaactgct tttaaaattt
     6841 ttctataatt gcttacgcca tctaaactta aaactttatt gacgattttc gtcactactt
     6901 cccgctgacg acgttgtcga ccgatatcgc cttctggatc ttcgtgtcgc attcgagaat
     6961 aggctaaacc tttttctcca ttcaatgttt gttcacctac tggtacatgg acaccatcca
     7021 aagtaaagtc aattttatta ttcactttga tgccaccgac cgcattgatc aaatcttcca
     7081 tgccatccaa attgatcgtt acataatgat caataggaat atcgagcagt tgctcaattg
     7141 aatccatggc catttcgaca ccaccaaatg cgtaggcatg atttaattta tctaccgttc
     7201 cataacctac gatattcgta taaatatctc ggtccaaact gatgatcgtt gatttttttt
     7261 gtttcggatt aactgttact accatcatcg tatcagaacg tccttgttcc gttcttccta
     7321 atccaccggt atctaaacct aatagcaaaa ccgaaaaagg ttctttgtca tcaatgctta
     7381 ctctctcaga acgtttggag gatattcgat tagagttttt agaaattttg tttactgttt
     7441 ggctcgcttc tcccataaat ctgattccgt atgctgataa tccggcaatc agcaaaacga
     7501 atacccctaa caaggttaat agaacttttt gccatcgctt cataatacac ctctgtttca
     7561 cattttctaa aatattgtct catataactg ttcaatcagc aaattcactt tttaatcata
     7621 agaaaacttt aaaaaacatt tttgtgtaac gattattatt ttttaaaatt tctcaaaatt
     7681 cttaactatc ataccatacc gtgaaaaaga tcgaaagacc gaatacacgc agttcgcaat
     7741 cgttttatct ttttttatgt attttttcca gaaaaagcga acaacaaggt attttccaaa
     7801 taatcgtgca gtaaaatgat cgcacatacc tttcccatct ttttaacagt ctttgcctac
     7861 cgttcagatt atcattcgat ttcacgacaa tttcttccta tgactggtcc ttttgttaaa
     7921 cccatcttct attcgtttta tttccagctc actgcatggc tcttaaaatg actcgaacta
     7981 gtgattgcat taccatcatc ttttaatgga tagatatgct cctcttcaaa gtaaaacgat
     8041 tttcttttaa agtaatagaa ttgacatggt aatgagtatg tatactagtg gtttcacaaa
     8101 tggtctttta ttcaacatcc aaaaactgaa atttctttaa aatccattac taacgaagaa
     8161 aatgttcctt gcttgataat tagttaggac atgtcaagtg aacaaatgca tttacttagc
     8221 caaaaaatct aaaaacttca taaatagaca aaaagacacg actctctaag aagtcgtgtc
     8281 tttattcaac aaattattat aatttagtca cttcagcagc ttgaggtccg cgtgcacctt
     8341 caacaatcgt gaattctact tctagacctt cttctaggct cttgaagccg tctccttgaa
     8401 ttgctgagaa atgaacaaat acgtcatctc cgccgtctac tgtaataaac ccaaatcctt
     8461 tttcattgtt gaaccattta accgttccgt gttccataaa tgtatatcct ccaaaaaagt
     8521 tcttgcaagt aaccttgcaa gaacattata cccaatttag aaaacgctag caagctttcg
     8581 ctcttttatt ttccaaatta tttttaagac tgatatgacg gaggaaatgg ttattttgct
     8641 gcttcgaaac gtttgtttac ttcatcccaa ttaataacat tccagaatgc tgcaatataa
     8701 tctggtcgga catttttata tttcaaataa taagcatgtt cccaaacgtc caaacctaga
     8761 attggtgtct ttccttccat caatggagaa tcttgatttg cagtagaggt aatagctaat
     8821 tttccatttt ccattacaag ccaagcccat ccagaaccaa atcgtccagc ggctgctttt
     8881 ttgaattctt ctttaaaaga agaaaaatca ccaaaagctt cattaatcgc ttcttttatt
     8941 tctcctgtag gttcgccacc agcatttggt gccatgattt cccagaaaaa tgaatggtta
     9001 gcatgtccgc caccattgtt acgtacagct gtcttgatat ctgttggaat agcgtccata
     9061 tcagataata attcttctat tgttttttcg cctaattctg ggtatttctc aattgctgaa
     9121 tttaaattcg tcacataagt attgtgatgc ttatcatgat gcagatgcat cgtttcttcg
     9181 tcaatataag gttccaatgc gtcatatgca taaggtagat ctggtaatgt gtaagtcata
     9241 aaaaaattcc tcctcaatgt tttcttaata atgtctacat tacaaagagt aacaaagaga
     9301 aggaaattct tcaattgtta tgcctagtcg tctttttcac tttgacctac ttcttcttca
     9361 aaaacctcag tttctttaaa aataaacaac ttgctgaaaa tatagttcgc aaggataaca
     9421 ataatttgag tgatgatttt cgccacatac tcattgctgt tcataacatt gatcaacaat
     9481 accattgccc ccatgtccaa tccgtaagaa aggatacggt agaagaagaa cttaccgcat
     9541 tcaataagtg catgtgtaaa attcggtgat tttgaatgga atacccaaag tttgttcgtt
     9601 acaaaagcaa acaatacaga acaaaaccac gaaatagaat tggataaggc catacttaaa
     9661 tcaaaatatt ggcgtgcgag agcaaaacta acaaaattta caatcgtagc caaaccacca
     9721 aaaaagagat agactagtat ctcccaatat ccttttgctt ctaaatatcc ttttaactgt
     9781 cgatactgct tcatgagcca acctacctta ttaaaaattc ttatttatca tactctatat
     9841 ttcaataact ttcatcttta tttaaaaaaa ttaatttttt ttgatccttt gcctttgtct
     9901 ctgcttggat cgtcacatgt gtaataccat attttaattt taataaagaa attatacgag
     9961 gatatatctt ttcaatctcg cttagtagct gatcttcaaa atcaatatgt ccgtcgaaaa
    10021 taattatctt ttcgctatac tgccaaatat ggacatgatg aacatccttt accccatcga
    10081 ttgcttcaat ttcttgttcc attttttcat agtcgatagc aggtgcactt tgtatcaaaa
    10141 tagcggcagc ttttttgatc accattatcg cttctatcaa tatatatatc gaaatgatca
    10201 gtgtaataac tggatcgatc cagtagatat cgaaaaaacg gatcaaaatt gctccgataa
    10261 tcacacttac cgaagacagt gtatcactta acaaatgcaa ataactagat tttatattca
    10321 aactttcatc tgcttcttgt cgtaataata atactgagaa caaattcgcg agcaatccaa
    10381 taactgctac tgttagcatc aaatgactat ttatcttttc tggtgaagtg aaccgcttga
    10441 atgcttcaac ggttaaaaac aaggataata tgatcaatat gaatgagttg atgaaagcac
    10501 tcaatatttc taaacgctgg tagccatacg tacgtttttt atttgcttct tttcgggcca
    10561 ttttttgtgc cccgtaagaa aaaataattg ccaatgtatc actaaggtta tggaaagcat
    10621 ctgaaacaag agacaaactc cctgacataa tccctccaat aaattctgat aaagtgatca
    10681 ccgcattcaa aaccactact ccaaatagtt tttttgatga tctctgtggc tgtgtaggca
    10741 ctattccttc ctccatttta tttatattgg atagtcttta gacaagaata acattttttt
    10801 gatatttcac caatcattca gctgtttcct taaagcactt gtatttcact tgatacttcg
    10861 ctagaattgc aagtgatgac actactagat gaggagtact tatgacaaca aaacaattaa
    10921 ttatcagttc ctttatacga ttcaaagacc taaaggagtc gagaaatgtc ccattttgga
    10981 aagccattgt ctatctttta gttttgagta taattatggc tttgccaatc tcttttcaag
    11041 tttttcaagt cttaaacaac attcaattgg atgggcaaaa gattgctact cgcattcctg
    11101 attttacaat ccaaaacggg cagcttcaaa ccgaagaaaa agaaggattc atttaccaaa
    11161 caaactccat tatcttcaca tttgatccag agggaaaacg aacagaacag gacatctcta
    11221 ctgatttgat ggggaatttt gttagtgtcg ggatgttaaa aaacaaactt atcatagctc
    11281 ttcctaatac aggcacgact tctgctttgt tgaacaataa ccaattagaa cttccctaca
    11341 ccaatgaatc tttaaaaaac ttaacaggta agcagctccg ttctttttta agtgaagcat
    11401 ctataccact ttggataaaa gtcctgacat ttatattttc tatttatcct agttttctga
    11461 atctgctgat cactttgcta tttaccaaca ttgctgcttt tctctatgca cgctttcgac
    11521 taacaaaagc tacttttctt gattgtttaa aaacattgat ctattcaatt tcattgccta
    11581 ctataattgc aacaatcttg atggtctttc ttccttcttt tgacactagc gccttcattg
    11641 cttttgcagg aatctttatt tttgctcaag ctgtcaaagg atgggcaaaa atatcgatca
    11701 attaagaaat aaagacaact cgttatttct acttcaatag acccttttag aggttgtgac
    11761 atttttttgt cacagcccct tttttatttg aaaaatattt ctttctcaaa aaacaagcaa
    11821 ggcgcttcaa agttcttctt gtatgcgcta cacttagagt aaagaaaggc gggaaattaa
    11881 ctatgtcaga aagaatcatt tatgcagatc gtccatttcg tgatgaattt atcgaagaaa
    11941 tccatactat agcgcctggt tatatcttta aaacagaatt acaaccagag gatctacaaa
    12001 atgtagagat cagtttgggc tggaactcag actaccaaga aaaactatta gcctcttcta
    12061 ccttgaaatg ggtccaatct atctcagctg gtgttgatca gctacccctt gagacttttt
    12121 caaagaaaca tattttactt tcaaatggta gtggcatcca cagtgaatcg attacggagc
    12181 atgtcttagg aatcatcctt gggtattctc gtggtctttt tcaagcacaa aaggcacaga
    12241 gtgacatgaa atggttaggt tcatcggtcc attaccaatc tatccaaggg aaaaaaatac
    12301 taatcattgg aactggccat attggaaaaa tgattgcaaa aaaatgcaaa gcattagaca
    12361 tgaactgcta tggaatcaat acatccggtc atccagcaga aggaatggaa aagacttttt
    12421 ctttaaatca actaaaggaa gttcttcctg aagtagattt cgtagtcaat atcttacctc
    12481 taacggagga aacaactggg ctctttgatc agcatatgtt tgaacacttt gatccaaaat
    12541 ctgtattcat caatgttggc cgtggtgctt ctgttaagac acaagatctg gtgcaggctt
    12601 taaataacca gcaactttcc tttgcagcat tagacgtttt tgaggaagag cctcttccac
    12661 aagatcatcc tctttggaaa atggacaatg tactgattac ttcccacatt gcaggtttga
    12721 cacctgattt tcaaaagaaa ttaatggcta tttttttaac caatctgaaa agctactttg
    12781 ccacccatga gcttcaaacc aatcaagtaa aattgtctgc aggatattaa tagctgaaaa
    12841 caatattttc aaaagaaaaa agagaaggtg acaa
//
LOCUS       DAYNVV010000073        12323 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.076, whole genome shotgun sequence.
ACCESSION   DAYNVV010000073 DAYNVV010000000
VERSION     DAYNVV010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.076"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..260
                     /locus_tag="ACGXWR_002387"
     CDS             <1..260
                     /locus_tag="ACGXWR_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803910.1"
                     /translation="LKRKVTDRNKNLLNVVMICYISFLILGLPQAVFPEMFSGDWGIV
                     SYSILTLIAMVLGTSFYNAFVSKHVEEYEVLMYLKEKKTSN"
     gene            467..667
                     /locus_tag="ACGXWR_002388"
                     /pseudo
     CDS             467..667
                     /locus_tag="ACGXWR_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1379..1984)
                     /locus_tag="ACGXWR_002389"
     CDS             complement(1379..1984)
                     /locus_tag="ACGXWR_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFK0803911.1"
                     /translation="MAKIGYIRVSSQDQNLDRQLAMMEDLNIDKLFQEKASGKDIQRP
                     EFQKLLNYIREGDCVIVASLDRLGRDYEDIKNTVTFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAKKAGRYKGRPIEYSENSTDPQ
                     KRLVFKTVVDMLNQGVPVAEIAKENGLSRPTIYKIKKANDL"
     gene            2166..2501
                     /locus_tag="ACGXWR_002390"
                     /pseudo
     CDS             2166..2501
                     /locus_tag="ACGXWR_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387932.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            2666..2881
                     /locus_tag="ACGXWR_002391"
                     /pseudo
     CDS             2666..2881
                     /locus_tag="ACGXWR_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3019..3990
                     /locus_tag="ACGXWR_002392"
     CDS             3019..3990
                     /locus_tag="ACGXWR_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFK0803912.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            4130..5443
                     /locus_tag="ACGXWR_002393"
     CDS             4130..5443
                     /locus_tag="ACGXWR_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HFK0803913.1"
                     /translation="MKKRMLAIAAILALTAGGLAGCGSKEKSSGSSDPGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFIWSNGGDVVNADGTKAEDYFNGKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMMLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIMSLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQLSGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            5486..6352
                     /locus_tag="ACGXWR_002394"
     CDS             5486..6352
                     /locus_tag="ACGXWR_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0803914.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQIGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            6349..7197
                     /locus_tag="ACGXWR_002395"
     CDS             6349..7197
                     /locus_tag="ACGXWR_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFK0803915.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            7211..8683
                     /locus_tag="ACGXWR_002396"
     CDS             7211..8683
                     /locus_tag="ACGXWR_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HFK0803916.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWMNDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMIAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQERIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPDHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            8700..9572
                     /gene="scrK"
                     /locus_tag="ACGXWR_002397"
     CDS             8700..9572
                     /gene="scrK"
                     /locus_tag="ACGXWR_002397"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HFK0803917.1"
                     /translation="MIYGSIEAGGTKFVCAISDEEMTIKERVSFPTTTPEETIPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKVAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
     gene            complement(9808..11190)
                     /locus_tag="ACGXWR_002398"
                     /pseudo
     CDS             complement(9808..11190)
                     /locus_tag="ACGXWR_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            11652..11975
                     /locus_tag="ACGXWR_002399"
     CDS             11652..11975
                     /locus_tag="ACGXWR_002399"
                     /inference="COORDINATES: protein motif:HMM:NF015824.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HFK0803918.1"
                     /translation="MDSFQRLSLVNQFELLAKFEDQNRSYYERKIEILREGYEYHYDD
                     EIWSDLSEPFPKEDSRFVLDVLNMYRDINFSKSKLNLDENQITNSYYTHFGSVAKFSK
                     KSILV"
     gene            12007..12323
                     /locus_tag="ACGXWR_002400"
                     /pseudo
     CDS             12007..12323
                     /locus_tag="ACGXWR_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
BASE COUNT         3837 a         2095 c         2480 g         3911 t
ORIGIN      
        1 atttaaaaag aaaagtgaca gataggaata aaaacttatt aaatgtagtt atgatctgtt
       61 atatttcatt tctaatacta ggtcttccac aagcagtgtt tcctgaaatg ttttctggag
      121 actggggtat tgtcagctat tctatattaa cattgattgc tatggtttta ggtacttcat
      181 tttataatgc ttttgtaagt aagcatgttg aggaatatga agtattaatg tacttaaaag
      241 agaaaaaaac aagtaattaa tatgagaaca ccacgcatag tttttatttt gagatattct
      301 agaatgaaac acattaagaa cgaaagcaaa gcaaaagacg ccagaacttc tactaccttc
      361 taagtttttt catatttgtt tgttatgcta tacatagatc tgcataatta gacttgcgct
      421 gcccgttatt gaagtttcag gcagcgctct ttttggggga tcgataatgg aagaagaaaa
      481 aatatttgag aaacgctggc agctagcatc aagtgaacaa agagcaagat acaataattt
      541 gatcacctcc taccccactg ttgactagac atataaggaa aagaaatact tactttggct
      601 gtgccagtta gatatagata cctttgaaac atttgaagtg atcctagata aaattaaaca
      661 gaattgatca gaaacaagcg aagccttctc tcggttcgct tgttttgcta tttattagtt
      721 ggctcagggc aactctaagc tcgtttgaaa gaaaaccgat ggataatccc cttgtttgta
      781 ccactttaga atacatggat gtacgtattg ccattgactc ctattagtta ctgaaaaaaa
      841 atttaaacaa gttgagtatt gcagataaat agctccagtg aggtgaataa ctgctccact
      901 caaggcaata gatagctcca tccagggcaa caaactgctc cactttcata tttaatagat
      961 gaataacctt ctgtataata gaaaggcata cctttcggta tgacaactta tacagaatgt
     1021 tattttattg gttcactatc gaaaaatttt ggagctttat ttttccggta tttctcaacg
     1081 aacgattagt ttaactgtgg gaagctccag acatacgatt cgagaagtta cttctcgagc
     1141 agacaggaag ggggtgactg aactaaccgc tgatatgagc gatacttggc tgtaggaata
     1201 tctttttccg gaaaaacaaa caacagcacg aggttacctt cctgtagact gggaatatgt
     1261 tcataaagaa ctaatgaaaa agaatatgac attgaaactc cttcatagag aatatggggt
     1321 acatggaaca tagaaacgaa aatgcacggt agaaaagcga atgaatatag tataaattct
     1381 acaaatcatt cgctttcttt attttatata tggttggtcg agagagacca ttttctttgg
     1441 caatttctgc aactggaact ccttgattta acatgtccac cacagtttta aagactaatc
     1501 gtttttgcgg atctgttgag ttctcagaat attcaattgg tcgcccctta tatcgaccag
     1561 cttttttggc caataatact ccttgccgct gacgttcacg gattttctca cgttcgtttt
     1621 gtgcaatata acttagcaat gataaaaaca tatcgaacat agcagtatct aggagttcat
     1681 ttccagtatt aaaatctaaa aactgtgcat ctagtatttt taatgctact tttttctgtt
     1741 tcataaaggt aactgtattt tttatgtctt cataatctct gcctaggcga tccagtgatg
     1801 caacaatgac acaatcacct tctcggatat aatttagtaa tttttgaaac tcaggtcgct
     1861 ggatatcttt accactggct ttttcttgga ataatttatc aatgttaagg tcttccatca
     1921 ttgccaattg tcgatctaaa ttttgatctt gtgaagacac tctaatatat ccaatttttg
     1981 ccataaaaac tccttttaaa aaatgatata atttacatgt aaaatttact tgtagtttta
     2041 ctgttatcat agcattttta aaaataaatt ttaagtctac ttataattta ctttggaggt
     2101 tttgaatgaa tgaaattaag cgcaataaaa attcttttgg tgtttattta ggagagccta
     2161 gctcggaaca gttaaataaa ggtgaagctc gtcatgctct atgtcgaaat atattttatg
     2221 gtagaaaagg caaactttat caaacttatt acgacggtat ggaggaacag ctcaacgcat
     2281 taggattagt aactaatgct atcatatatt ggaattcact atatttagaa aaagtctttg
     2341 aacaaattaa aacggaaggg ttcgactgtt ccgaagaagt gttacgcaag caatttccat
     2401 taattagtga tcacattaat tttgttggca aatatagttt ccgctatgaa aaagaattat
     2461 cgaatggaat actacgtccg ttaaatatag agaattattg agaatgttcg tcttttggtt
     2521 cctaccgtgc attttcgcac ggatgttcca gatactattt ttgaatgtat aaaattgaaa
     2581 acacaagaat actaataaat caacgattct tgtgttttta atttttcact accgtgcatt
     2641 ttcgtttcta tgttccatgt accccaatct tgaaaaatta attaaagact tagataaagc
     2701 cattgacgac ttagtcgtgg tgctaccgga gtatcaatgt ttaaccagta tcccaggtat
     2761 tggtcctgtt taggctgctg gaatactcgc tgaaattggt ccaattgaac gtttttctga
     2821 tgaaataaaa ttgacaaagt atgccggcct atattggcga cagagtcaat ccggtaaatc
     2881 tgaatacgaa aattttttta cgaaaagctt cacgtctaat atctatttta aaataaaaat
     2941 attcctgcta atttggaatc gtttccttct tttggtataa taatacctga aattcttttg
     3001 agaggagttg ttcgtgaagt gaaaactact atgaaggatg ttgctgcgtt agcaggagtt
     3061 ggtgtgggta cggtatctag agtaataaat ggagtaaagg tgaaagaggt taccaaagaa
     3121 aaagtaatgg ctgcaattag tgagcttaat tatgagcctg atgaatatgc cagaggtatg
     3181 aaaacgaata gtagcaatac aatagctctt attttaccta cgatttggca tcccttcttt
     3241 tccgagtttg cctactatgt agaggaagct ctcagccaaa aaaattataa gctttttttg
     3301 tgtaatgcga acggcagtgc ggaaaaagaa aaagaatata tccaaatggt caagcagagt
     3361 aaagtagacg gaattatagg tattacctat tcagacattg ataaatatgt atcatcaaat
     3421 ttaccatttg tcagtataga ccgccatttt tcggaacagg tttcttatgt aacggcagat
     3481 aattatttag gtgggcaaat tgccgctcaa gaactactta ctcgtaactg taaaaacttg
     3541 tgctatgttg ggggtgtttc accttaccct aacgaaacaa acaatcgtaa agctggtttt
     3601 tacaatattt gtgaggaaaa taaaatagct gtgaaggtat tggatatgcc tgaaccaatt
     3661 agcaatttag aggaacaatt gctcgctttt ttttcggata atcctgaaat tgatagcatt
     3721 tttaccatca atgatttcat ggctttggat gtgataaaag cccaaaaaaa actagggaag
     3781 gaagcaccta aggattttca aattattggt tttgatggag tcaagctatc gttgcaaaaa
     3841 gactatttac tatcaacgat tgtacagccg atagaggaaa tggccaaggt ttcagtagaa
     3901 acactcatgg cgatgatttt aaatgaagaa ccgcctaagc gtgtggtagt accggttttc
     3961 tttcacgctg gagagacgac taaagagtaa aaaaccggtt tataacgatt tttttgagat
     4021 aggttgacag aaagtgattt caatgatatc ttaaaaccaa ttaattggaa acgttaccaa
     4081 ttaattgaaa aataaaacgg aaacgtttca aaaaatagga ggaacatcga tgaaaaagag
     4141 aatgttagca attgcagcaa ttttagcatt aacagctgga ggacttgcag gatgtggcag
     4201 taaggagaaa agttcaggta gcagtgatcc aggagaaatt aagatttggg ttcagttttc
     4261 tgatgaaacg cctgaaggaa aagcttgggc agagattgtg aacaatttta atgatgaata
     4321 cgagggtgaa tataaagctg ttactgagta tattcctcgt agcggaagcg gcggtggata
     4381 tgaggataaa gtaaatgctg caattacaac caataccctt cctgatgtta ttacgttaga
     4441 tggaccgaat actgcagctt atgctcattc aggagtcatt gctccattag atgattattt
     4501 gaaagatgcg gacatggatg atgtattaga cagcattatt cagcaaggaa cctacgatgg
     4561 caaaatgtat gcgtttggtt tctcagagtc cagtgtgggt gtctattaca ataagtcgct
     4621 gttcaaagat gctggaatta cagaagatca attgccgacg ttagaagatc cttggacttg
     4681 gacggaattt caagcaattt gccaaaagct gactgataaa tacaaaacgc ctgcaattga
     4741 tatgcaaatg gcgtcgggag acgaaatgct gacctacgca tatacaccat ttatatggtc
     4801 gaatggcggc gatgtcgtta atgctgatgg aaccaaagcc gaagactatt ttaacggtaa
     4861 aaaatccgtt gaagcgttgg aatttattca agaattggtt gaaaaaggtt acaccacaat
     4921 cagtcctatt gaaaaaggat ttgaaactgg caaatatgcc atgatgctga gcggttcttg
     4981 gacaatggca gatttagagg aaaactatca agagattgat tatggtattt tgccttaccc
     5041 cgtttcagat gcaactgggg agttagtttc accaaccgga agctggcagt tagcaatgac
     5101 tgagaaaaca gagaaaaagg atgcttctgc ggcctttatt aagtttgcaa ccagtacaga
     5161 atctagtcgt attatgagtt tagggaacag tgttctacct atcagaaatt caacagttga
     5221 tttaattaaa gatgaagtgt cggaaggaat gcaggtatta attaagcaaa accaactttc
     5281 tggacatgcc cgcccagtgg ttgtagctta tccgcaagta tctagagcat tccaacaagc
     5341 agttcaagat attagctact tcgaggaaaa cccagatgta caaaaagtag cagatagtcg
     5401 cgctgctgaa atgcaacagg caattgatac ttcactaaaa tagaagtttc taaagggggc
     5461 caatcaagtg ttaaaaaaac cgacaatgaa agacaatttg ataggttacg gctttctagc
     5521 gccagctttg ctgctgctga cgatttttct gatcataccc gtaatcatgg taatttatta
     5581 tgcctttact gattattatt tgttaacgcc agatgctaga caatttatcg gcttagaaaa
     5641 ttttaagcga ctgttcgctg atccaatttt tgtaaaaagt atttggaaca cggctaaatt
     5701 tgttgtttgg attattccgg tccaaatagg ggcagcttta ggaatggcac ttattatcaa
     5761 caaaaatcgt aaaggaaata tcttttttaa agtagccttt tttgcgccag tcgtgatgtc
     5821 cttagtcgtt atttcgattt tatggttgta cttgttaaat cctaatgaag gtctggttaa
     5881 tacgctattt gcaaagattg gaattgcttc gcagcctttt ttgactagtc ccaaacaagc
     5941 aatgtatacg cttgttttcg tatcggcatg gcaaggtgca ggatatcaga tgctgctgtt
     6001 tttaggggga atgcaaaata ttccgcaaga cgtttatgag gcagccgaaa ttgatggttt
     6061 ttctaagttt cagcaatttc gctatatcac catgccatta ttaaagccca cggcgatttt
     6121 tattttactt accacattga tttcggcctt taaactaatc attcagccaa tggtaatgac
     6181 tcaaggtgga ccaatgaatt ctactatgac aatggtttat tacatttacc aaactggatt
     6241 tacagaccgt atggtaggct actccagctc cattgcgtta atctttacca ctatgattgg
     6301 tttaattaca attgctcaaa gaaaattggt aaaggaggat gatccagcat gaccaagaaa
     6361 tttggaccgc taatgatcgt agaatattgt ttgctgttcc ttttagcggc attattcatt
     6421 ttcccgatgc tgtggatggt agtttcctct atgaagcctg aagcagatgt ctatcaaaat
     6481 ttagcttcct tcaaagcttt tttacctagt ttgaatccag ctaattggtt taaaacttat
     6541 caagaggtta tttcccggtt cagtgtggga acttatttat taaacagtat tttttatggt
     6601 ttaacctttg cctgtgggtc aatcattgta aactctttgg cgggttttgc ctttgcgaag
     6661 gttaattttt caggcaagaa aattatcttt ggagctttgt tagctctgct gattgtcccg
     6721 atggagacgg ttttaattcc gcaatttacc atcgttaatt cactaggctt agtgaatact
     6781 cgcttggcag tgattttacc agcgatggcc agcgcgttta atatctatct gtttagaaat
     6841 ttctttatcg cgattccaga agaaatcatt gaatcagcga aattagatgg tgcaaatatt
     6901 gttaaaattt tctttcacat catgctgcca atgtctaaac cagccatagc cacagtaggt
     6961 gtcttatcct ttatctccag ctggaatgat tatatttggc cgttaatggt cttaactgac
     7021 agcagcaaat tttcaatgca agtggcaatt actacgatca atactacaca gccagtttat
     7081 atcaatcaag tgatggctgt tttaaccatt gcaacgattc cactgattat tgtttatatc
     7141 gttgcacaaa aatatattct gcagggactt ggcggttctg gaacgggtat aaaataggag
     7201 tgaatagtga atgttgcaaa aacttttaaa ggccaatgag tttattgaga aaaatgctca
     7261 aacagtcaat caagaatacc ggaataaatt tcatttgatg gctccgattg gctggatgaa
     7321 tgatccaaat ggttttgttt attatcaaga ggagtatcac ttgttttatc aatattatcc
     7381 ttacgacagc atctggggac caatgcattg gggccatgct aaaagcaagg atctaattca
     7441 ctgggagcat ttgccagtag cactggcacc aggtgaaagc tatgacaagg aaggctgttt
     7501 ttccggcagt gccatagaaa aggatggcaa gctgtatttg atttatacag gacacaatgt
     7561 tgtggaaggg caagttcgac aagttcagtg tttggcagtt tcagaagatg gcattcactt
     7621 tgaaaaatat gccggaaatc caatcatcgc agaagatcac ttagcttctg ttgcaacgac
     7681 cgaagatttc cgcgatccca aagtgtttca gcgaaaagaa gactatttta ctgtagtcgc
     7741 tactaaaact gcagatgctc gtggacaaat tgtgatgttc cattccaaag atttactaac
     7801 ttgggagttt tattccgtat tgctggaggg aactccagaa caaggcattg tatgggaatg
     7861 cccagacttg tttgaactag atggcaaaga agtcttgatt ctttctccta ttcaaatgac
     7921 tccacaaggc aatgcttacc aaaatacgaa ctcaactgtt gctttcatcg gtactgtcga
     7981 ttggcaaaca ggcaaatttc tagtagagaa ttttcatgaa atcgatggcg gtttagattt
     8041 ttatgcaccc cagacctgtg aaaacgaagc aggccaaaga ataatgattg cttggatgca
     8101 aatgtggcag cgtaaaatac ctacgaatga tctgggccat ggttggtcag gttccatgac
     8161 cttgcctaga gagctgaggg tggctgataa tcaattgttg caacggccag tttcatcaat
     8221 ttatcaagta attgatccgc aggaaaggat tgaatgggcg aagactgaag agaatcgctt
     8281 cttactgaag gacttagtat atgaccagca ctatttacgc ttggaaatca atttaaaaca
     8341 ggcaacgaaa ctagaacttc actatgcgaa gggacccgac catacattac tgcttaacta
     8401 tgatgttgaa cgggagtgct ttactgcttc cagggaacac atgccgtatg atttatcagg
     8461 agctgaaaag gaagtgttga aaaagcgcag tgtgacgatt cctttggaaa ataattgtct
     8521 aaccatcgaa attttccgtg atacttcagc tattgagctt tttctaaatg atcgtctgac
     8581 tatgagtaca actttttatg agacagaaaa aggacaggat tttcttttgc tggcagacag
     8641 tgaagtaacc ttttcattgg aaagcggctt aattaatcta tagaagggag agctcagtga
     8701 tgatttatgg ttcaatcgaa gcaggcggca caaaatttgt gtgtgccatt agcgatgaag
     8761 aaatgacgat caaggaaaga gtgagctttc cgacaacgac acctgaggaa acaatacctt
     8821 tagtcattga cttcttcaaa caataccaag cagatttagc agggattggg attggctcat
     8881 ttgggcctat cgatatccat cgcgattccg ccacttatgg gtacattacc tcgaccccga
     8941 aagtggcatg gcaaaatttt gatttcatcg gtaccatgaa aaaagaattt ccgatcccga
     9001 tttcttggac aacagatgtc aatgcggctg cctatggtga gtatgtcttc ggcagtggca
     9061 aaggattgag cagtgtcgtt tactatacga tcggtacggg tgttggcggc ggtgccttac
     9121 aagaagggcg ctttatcgaa gggtttagtc atccagaaat ggggcatatg ctcgtcgtcc
     9181 ctcatccaaa agatgacttt gctggcagct gtccatttca tggcaactgt ttagaaggga
     9241 tggccgctgg acccgccatc gaaaaacgct tagggaaaaa aggacaagag gttgcagaag
     9301 atgatcctta ttgggaaatc gaagcctcct atattgctca atgtgcctac aatacaacct
     9361 tgatgttttc tccagatgtg atcatttttg gcggtggtgt gatgaaacaa cgccatatgc
     9421 tgcaaaacgt ccacgacgca tttgcaaaat tggtcaatgg gtatgtcgaa acacctgagt
     9481 taagcaaata tatcgtgacc ccagcattag aagacaacgc tggaacgctc ggttgtttgg
     9541 cattggctcg agaagcggtc ttacattcat aaacgaaaaa aggctcttcg acatttagtg
     9601 ttggtagaga aagatacaac tgaaaattta gtcataacca gttaggcaga gtgcttaact
     9661 ggtttttgtt ttacttggaa gatcaagcct tgaatgagat aagttcttgc tcgaaagtta
     9721 tggaaatttc gatagccgta ggctacttgt attgtgcaat agttttttac aaaaaaaagg
     9781 gggtgcggat attttttttg gaccttttta acaaatatat ctttgcttct tccgatattg
     9841 aagagggctt agccttccta aagataactt aattcgttga ttattatacc aatgaatata
     9901 atcatccaat ttgtttataa actgattgat tgttgtattc ttccagtcac gttgataaaa
     9961 catctcgttt tttaatcgtc caaagaaacc ttcgcacgct gaattatctg gtgaataact
    10021 ctttttagac atagagtgaa gcaagttggc tttgttccaa tagtccaact aacaatagca
    10081 ccatcgtaac aatcgacaag tggtgataag tagattttcc ctgcgagaat tctaaattca
    10141 gtaatatctg ttaaccattt ttcatttggc ttctttgctt taaaattccg atttaataaa
    10201 ttggggtgtg caggagaaat ttccccagca tacgaagaat acttttttcg tctagaaaat
    10261 ttaacaaata gattttcctc agtcatcaat ctacgtacaa ctttttcaga aagcttttta
    10321 cccatatttt ttaaagcttg gtgaattcta cggtaaccat acgcacagaa gttatgattg
    10381 aaaatcgtga taattaattt gacgttcttt gtaatactta tctggtttct caagtgcttg
    10441 tttttgataa aaatagctgc ttttaggaaa ctggagctgt tgaagaagct ctttcaaggt
    10501 gaactgattt cgtaaggcat caatcaatat cgttttttct tgatttgata gacaaagaag
    10561 attgacgcct ttttcttttt ttagcagttc agccgctcct tcgagtaatg ctttttcgag
    10621 ctgtaattgg tgtacttgtt tttgtaagtc ttctacttcc tttaaaagta gctctttttg
    10681 tttttcctga ttttttaaag tcatacacaa tggaaaatcc tttccaagaa ccgtgttttt
    10741 ccattgatat agagtaactc tactaattcc tccagattcg gctaaatttt tcctattagt
    10801 ttgcggttta tagaattttt tcaacacagc ttctttttga tcttgtgtta actttaccgc
    10861 actttttcgg agttttctag ctcctggtgc aagttcttca caccgctgcc gcaaggactc
    10921 tctattagga taaccaagca tgcgaatggt tcgtgcataa cattgaccat attcaaaata
    10981 atgattcacc gctattcgtt tttgttcttc agaatacttt gatttttttc ggtgctcctg
    11041 atggagctct ccggattcca aatactcttt ataccatttc cgtagtgcac caatcgacgg
    11101 ataccctaat tctcgaatgg ttgcagcata agagcaatcg tattttaaaa ataactgaat
    11161 tgcccttaca cgctctttgt gggaaaacac acggacattc ctcctaagtt tattttttcg
    11221 tccaggatta tgtccgcacc cccttgcttt ctgatgactt attctggttc tttgagtgtc
    11281 aatgcataga tgtgatgtag ctagttagaa aaaaattttg aatactcttt ttttctttca
    11341 gactcctttt taagtaagat tttgaagtgt gagttacggg gtcagaaact taaaagtttt
    11401 tgatccttta ttttcaagtc tgatttggca gcttttcggc agctcattta tttatggtca
    11461 gaaatagatg ctgaaatttt aatctattag caaatagtcc agaacgtatg aagaggagtc
    11521 ggatatcatt tgtcattaac accataaata tttataaaat tcgtgttcac ctacaattaa
    11581 atttaatata taatattcgt tgtaagggct tataattttt tgttaatgaa caagatagga
    11641 agaaacattt aatggacagt tttcagagat tgtcactagt aaatcaattt gagttattgg
    11701 ctaaatttga ggaccaaaac agatcttatt atgaaagaaa aatcgaaata ttgagagaag
    11761 gttacgagta tcattatgat gatgaaattt ggagtgatct ttctgagcca tttccgaaag
    11821 aagattctcg atttgtatta gatgtattga acatgtatcg agatatcaat tttagtaaat
    11881 caaagctaaa cttagatgaa aaccaaatta ctaattcata ctatactcat ttcggttctg
    11941 ttgcaaagtt ttccaaaaaa tctattttag tgtaaaattg agaaaaaaga cagagaggac
    12001 agagtaatga atcattttaa aggcaaacaa ttcaaaaaag acgtcattat tgtcgctgtt
    12061 ggttactacc tgcgttacaa tctaagctat cgtgaagttc aggaattgtg atatgatcgt
    12121 ggaataaatg tttgtcatac tacgatttat cgttgggtac aagagtacag caaagtcctc
    12181 tattatcttt ggaagaagaa aaatagacaa tccttctatt catggaaaat ggacgaaacc
    12241 tatatcaaaa ttaagggacg ttggcattat ctttatcgtg caattgatgc ggacggctta
    12301 accttagata tctggttacg aaa
//
LOCUS       DAYNVV010000074        11838 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.077, whole genome shotgun sequence.
ACCESSION   DAYNVV010000074 DAYNVV010000000
VERSION     DAYNVV010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11838
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.077"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(560..1600)
                     /locus_tag="ACGXWR_002401"
     CDS             complement(560..1600)
                     /locus_tag="ACGXWR_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFK0803919.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1949..2275)
                     /locus_tag="ACGXWR_002402"
     CDS             complement(1949..2275)
                     /locus_tag="ACGXWR_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803920.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2262..3050)
                     /locus_tag="ACGXWR_002403"
     CDS             complement(2262..3050)
                     /locus_tag="ACGXWR_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFK0803921.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQG
                     NATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVG
                     SEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKL
                     SETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRRT
                     ITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3418..3708)
                     /locus_tag="ACGXWR_002404"
     CDS             complement(3418..3708)
                     /locus_tag="ACGXWR_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HFK0803922.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(3844..4023)
                     /locus_tag="ACGXWR_002405"
     CDS             complement(3844..4023)
                     /locus_tag="ACGXWR_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803923.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4020..4370)
                     /locus_tag="ACGXWR_002406"
     CDS             complement(4020..4370)
                     /locus_tag="ACGXWR_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803924.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4363..5688)
                     /locus_tag="ACGXWR_002407"
     CDS             complement(4363..5688)
                     /locus_tag="ACGXWR_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFK0803925.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            6138..6752
                     /locus_tag="ACGXWR_002408"
     CDS             6138..6752
                     /locus_tag="ACGXWR_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFK0803926.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(6917..7159)
                     /locus_tag="ACGXWR_002409"
                     /pseudo
     CDS             complement(6917..7159)
                     /locus_tag="ACGXWR_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7363..8682)
                     /locus_tag="ACGXWR_002410"
     CDS             complement(7363..8682)
                     /locus_tag="ACGXWR_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HFK0803927.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            complement(8816..9424)
                     /locus_tag="ACGXWR_002411"
     CDS             complement(8816..9424)
                     /locus_tag="ACGXWR_002411"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803928.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSLNNSYF"
     gene            complement(10062..10319)
                     /locus_tag="ACGXWR_002412"
     CDS             complement(10062..10319)
                     /locus_tag="ACGXWR_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFK0803929.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(10312..10581)
                     /locus_tag="ACGXWR_002413"
     CDS             complement(10312..10581)
                     /locus_tag="ACGXWR_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFK0803930.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(10712..10891)
                     /locus_tag="ACGXWR_002414"
     CDS             complement(10712..10891)
                     /locus_tag="ACGXWR_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803931.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            10989..11225
                     /locus_tag="ACGXWR_002415"
     CDS             10989..11225
                     /locus_tag="ACGXWR_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803932.1"
                     /translation="MKQNTSIAKNTTKFKCTAAAWRISISPTNRTNNRGMILFIWISF
                     FLLGYRVLPAYFAPPKRRGRLERLVRNKNHSLSY"
     gene            complement(11272..>11838)
                     /locus_tag="ACGXWR_002416"
     CDS             complement(11272..>11838)
                     /locus_tag="ACGXWR_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803933.1"
                     /translation="EEQLYLESETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETE
                     KYIMNVYLERSELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATID
                     DYYLVFTRFLTCGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTY
                     TYDDTEEIQNELDRKRMPYQRFERKKRQ"
BASE COUNT         3604 a         2163 c         1789 g         4282 t
ORIGIN      
        1 ccgttgcggg taataccgta acactgaagg gcacgcatta aggcgtcatc ttaatgcttt
       61 cctgtaggac actgacggag attaccagtc tcccgagcct tacaggggcc tttctttttt
      121 ttgtattttc aattatcaca atttatcgtc caaaagtgca gaacgaaaat caattcatca
      181 caagcatatc agacaattaa atttaaaaca actaaaaata tacaaaaaag tgtaattgaa
      241 tattagcagc actgcctgaa aagaagtaat atcaggcttt tcagcttggg gaaataagtg
      301 aattacctct cttcatgaat tattataact caaaaaagca catatgcaaa cactagttcc
      361 ctattttttt gaatgaaaaa taactaaaat atctaacgat tatgacttta aaacctacgt
      421 ttgtgattgt tttcataaac ttttaatcta aaaactccgg aataatagct atttatttgt
      481 aacatttgta ataaaattaa aatcataaaa aagttctaat ttaaaattga tcatttttat
      541 agtgatcgct ttttatcaac tactctagcc aattttccgt actaactgtt ggtaattcgt
      601 taaatgtttc tctttgttcg tttgcaagct ttgccgcaat agctttttcg acaaaccaat
      661 tttttacata aacgaaaatt agattctgca aattgtttac tttttcagtt ttttgttttt
      721 gataagcttt cagcaaagtc atatataatc ctttgtcagc atcaattcca taagattcca
      781 gttcttcata aacaacaact gtttgctcta attcttcagc ttttttcttt gcattatgaa
      841 tagtttggac ggttttttga gcgtcttcgt aagtactaga aaatgttttt atcaagttta
      901 atacattttc tggtacaaat gtatttatac tgtcctcttt catgatgtcg acgaagttat
      961 ctagtaaaac ttgattttgt aactgatcag tttcagtgtc tattatgtgt ctattagtgt
     1021 ctatagaatt agaatagaat agattgtctg cgattttcgc aattacggtt gagtccttga
     1081 tatgactgga ttttgccgta tttgcgattt tcgcaattac ggtggtatca ttgatttctc
     1141 gcggttttgc cgtatttgcg attttcgcaa ttacggtggt atcagtattg tcttcctctt
     1201 ccatgatttt aaagacgtct tgattcgtta cttctggctt gcctaagtac aataaattag
     1261 gcatggattc aatcttaccg tcacgtttat ttactcttcc tctcttctgt ttcagaagac
     1321 ctgctttttc taattccttt ttgattttag atactttacc ttcgcggcat tgtaacaatt
     1381 tcattaattc ttcaactgtg aatatgaaaa atatattatc atcagaatct acccagttat
     1441 ttttgactga ataatcaaat cgatctttaa gtagcatata agcaattttt gcatcatttg
     1501 atagatccat gtatttttcg ttagtaaaaa ataccttagg catttgataa tatttttcac
     1561 gataaatttc ttttgatttg taataattaa aatcattcat agccaatcct ctttctgtag
     1621 gatagcgttt tgttcaaaac tatgttacaa tgaattaaac aaatatatct atccactata
     1681 tatttttcta ctgctgataa gtcgccaaac tttgttaaag cagtagtctt tttttatctt
     1741 tttttagttt accttaaaaa ataaattaaa gcaaaccgct ctatttcaag gtttaagctc
     1801 atagtaacta tatcacgata ttacaataat attatatcac gatatcgtaa tattacaata
     1861 tgaagataag cgacttatca gctttgatac tactgatttt tataaaaaaa atatcacgat
     1921 attatgatat cgtgatattg aatgtaaatt aaattttatt ttgtttcttt gctagtttat
     1981 atccttcaat caagtattct tcaggtatgg actttaatag cgcatcttct ataacgtctg
     2041 gtttactttt gtctgattca gcaatagtcg tccaatattt gagtgctgac attagaattg
     2101 gatttatacg aatgctatct gctgttctta cactacttcc ttgatctttt atgactttac
     2161 ttatattttt cttggttaat tcgatttctt ctacttcttt tgatttaaaa ttctttttat
     2221 ttttatttcc tagtaatcta cttactgcag cttgactgcg attatcttct gccatcaaaa
     2281 tcaccaactt cttttaaata ttcttctgta aatgctttat agtcatcttc agctgttgag
     2341 ggtttattaa aattgattag atctgatcca gcagcttgcg cttcgtcaac ggttattgtc
     2401 ctacgaatat aagttttgaa aatttttgca ccaatgactc tagaaatttc ggttgctgca
     2461 gacgtcattt ctttagaaat gttataacgc ttattatact tagtaaatag aactcctcgt
     2521 acttcaagct tgtcgttcgt atattctttt accgtttcaa tagtttcact taactttatt
     2581 agtcctttta atgagaaata cgcagcttca actggaatga taatttcatc agaaacagta
     2641 aatgcgttga ctgtaagcat tcctaaactt ggtggacaat caattataat ataatcatag
     2701 ttgtccttga ttggttgaag tactctttta agcctgtgtt cacttcctac ttgagtaaat
     2761 tccctctctg cagaagaaag ggctatgtcg gctggcaaaa catcaattcc tttatagtcc
     2821 agaatagcat ctgtaatgtc agcctcccct tttaatactt cataaattgt aggttggttt
     2881 gttccatcta tatcgaaacc tacattatct gtagcatttc cctgaggatc aatgtccact
     2941 aaaagtacat ttttaccgta aacaaatttc aaacatgctg ctaaattaac gctagtcgta
     3001 gttttagaaa ctccaccttt ttgattggct actgacaata ttcttgccat taaaatatcc
     3061 cccattcatc ttatattata atataattat atcataatat tgtgatattg caatatcgta
     3121 tatgcattat attgtaatat tgtgtgatta ttttgtttta aagatatata tcggttcgga
     3181 tataaagatt attcatatgt tattcgaaat taaaataatc actttttatt actttaaaat
     3241 tttttattaa tgataagaaa tatgttttgc gagcagcaac tagaataatt taaacattac
     3301 taaactgtct atattgttac taataattcc cttcttatag tgcattttct tagaaaaaaa
     3361 caatattacg atatcatgat attaagatat cgtaatatta tacaattgtg attgatatta
     3421 tatatgtttt tttatttttt tatcatgttt aatcttgaag gaatcatatt ctttttctaa
     3481 agacaggagc ttttcataaa catcagacat gtttaaacta gaggccaggc ttaaatcata
     3541 aacgaatgaa gcaggtaatg attttattct acgttgtcgg gttatccagc ttgcaaccgt
     3601 tccttgtggg taggcatata actcacaaaa ttgttctaca gtgattccta aattcttgat
     3661 aatgtaaaca ttgatcgggt gcgagtaaac aaatgtattg atagacatgg tgcgtaagcc
     3721 tactttcttt tattattgcg tttgcaataa tagtttaaca cacgcattat tctagtatct
     3781 actcctattt gtaaaaacaa aaaaggattc atagagataa ctctatagaa tccgtaaaat
     3841 accttatata tataacggga agatataaaa cctaaaatta tgataacctg ctgcagcttc
     3901 tacatagaaa gagaagcgct caacaccaac ctcatttatc aaacgttggc cataacccca
     3961 aatctcttct gatagctgat caaaggttat atactttagc tcatattgct ggataatgtt
     4021 cattctaatc gactccattt attatcctgg taaaattcga tatgacgtat ttcgtcgtag
     4081 tgaattttgt cttttccaac gtagatcccc agctcatcac tacctaagat cttgccaatg
     4141 atatcttctg gatagtatcc ttcagcgttt cgttcttctt tttgaataga tactgatcta
     4201 ttttttatga ctgcagcgtt caatacttcc gcaatctctt cagtcgtcat ttgttctttt
     4261 gctaaatttt gactggttcg ttgttcattg tcggcatcaa tttcttcagt atgatcagat
     4321 aaataaaacc ctgcccactt taaacgtcca cgatcattgt aatcaatcat ttttaattcc
     4381 cccatttccg cccgcatgac caccaacaag tgtgcttcta gtaatgcttc tagcgccttc
     4441 taacattgaa gaagcatgta caatcgacgt aaaaccatat ttttgccgaa tcttgtcaat
     4501 aattttatct aaattttctt cgtcaatttg cttttgtgga tcactaaata aatccagctg
     4561 aagcgaatcg gtgtacacaa gcttgctata ggttattcca acatgcctta cttcttgtcc
     4621 ttcataatac ttatcaaaca agaaaagaca ataattctgc aattcctttg tattatctgt
     4681 gatagggatc ttcatctggt gtgaaaaccc tggtctcgtt tctaagatcg acgtgccaat
     4741 gtgtaaatgg acacaacctg ttttacagtt atgctgccta atgcgtatcg ctacttgttc
     4801 cgccatttct tttaccacca gctcgatttc atttcttcta gtataatctc gtggtaacac
     4861 ttgtgaattt ccatatgatt tttcctttgt cggttctggt gggattgcta tatctgttcg
     4921 atcgatccca ttagcatgga agtacagctg taagccaatc acacctagtc tattcttaat
     4981 cgtataagga ttccagttag caagatctct aatgctcata atccccatct gattgagtct
     5041 ttttttcatt cgagagccaa ttccccaaaa gtccgtcatt tcaggaatat tccatacttt
     5101 ttcaggaacg ttttcgtacg tccattccgc aacaaatcct tcattatgct ttgcttcgtt
     5161 gtctaaggct agtttagcca aaaggggatt atctccgaca cctactgtag caatcaatcc
     5221 tagctcttct ttaatattct cctggatcat ttgagccagc ttctttctcc gttgacttcg
     5281 tgttccttca gtcgtaaaaa gattcagtga tcgggtcact tttaagattg attcatcgat
     5341 cgagtaaatc agtagatctt catcagccac atatcttctg aaaatattat ttacctgcat
     5401 atttcgcttg atatataggt tcatacgtgg tggaacaacg tgtagtgttt taggaaatgg
     5461 ttgtggtaag tcacgtggtc tactcacatt tgtaatacca taccgctttt ttgcttcagg
     5521 agaagaagct aatatcaatc ctgaaccagt attatcagct cgactcataa caacaagttc
     5581 tgttgttaat ggatctaaat ttctttctat acattcgaca cttgcgtaaa agcttttcat
     5641 atcgattaaa aagtaatcat ttactggctc ttttgaataa tccatcataa ataacactcc
     5701 attctttcac attatacaaa catatgttcg atattgtaaa gaagaaatag ctaaatacat
     5761 aaaaaaagaa gcataggtat gctatcaccc tgcttcttct tttgatttgt atgatcaatt
     5821 tattctatca ctttactaat taatttgaaa atctaataaa aactctcact ctaaaagagt
     5881 gagagactgc aaattagagt acggactttt ttggagttcc gttctttaat attaacaaat
     5941 gaataaaatc cttacaacat ttgagaataa gttatcagta gacacttaca aaaaattctc
     6001 atactatttc ctccatcatt agtttttgtc tatataaggt ataccctaaa tagacactgg
     6061 tataacattg aaaaatatgg cttcctcgtg tatgattagg gtgtatttta aatagttgca
     6121 gaaagtaggt aaaagttttg agagttgcat acatacgtgt ctcatcgatc gatcaaaatg
     6181 aacaacgcca gattgaagaa atgaaaaaat tcggtgcaga gagaattttc atcgagaaac
     6241 aatctggcgc aacgattact catcgacctg ttttccaaga agcattagat tacgtccgag
     6301 atcaagatat ttttattgtg gaagctattg atcgacttgg aagaaattat gacgagatca
     6361 tcgcttcagt caattacttg aagaagaaaa atgtgaagct gatcattact agtttaccga
     6421 tcatggctga agcaattggc aatcctctcc tggataaatt cattaaggat ctgatcatcc
     6481 aaattttggc catgatcgct gaacaagaac ggactgaatc gaaacgtcgc caggcacaag
     6541 gaattaagat cgcaaaagca aacggcgtct acaaagggcg gcccaaatta tacagtgcag
     6601 acgcaaaaga tccccaacgt cgccttgttt acaaaagcat cgttgaagat cttaaaaatg
     6661 gtgttgcgat tgctaagatt gctaaagact acaatgttac gagacaaacc gtgtatagaa
     6721 taaaaaaaga cagcatggtc aatgacaaat agttgatcat gctgctttta ttatcttctc
     6781 atctttaatt tcctacatat aattactatc tataaaatta agtcttactc agaacagata
     6841 aagcataaaa ttccaacaaa ccatttttta cttaactaaa taaagagtct gttaatataa
     6901 tcttcactta tttacgttaa tcccctactg tatttgttgg ttccttatct atattttcta
     6961 caaaatcctt attatcttgt gatttagctt cgtataattc tttgtatgtc gacacattgg
     7021 ttatactaat tcctatagct agttcttgag actctacttt tctctctagc tcctttgaca
     7081 aagtgatttg agatttattt ggttccgttg gagtcaattc tatagattct tcataaaaat
     7141 ctctatacat aaagctatcc ctgaataatt catagcttta attctttggc acattttatt
     7201 gaaatatgta tcactaatat ccctatcaac tgattttgac taaaaagtta cttcaaacat
     7261 tcactgttca aaaatattga ggaataaatt ttgggtgtaa ggcattttga gcatacttct
     7321 ccctggataa cttcccagta aaaaaatcgt tagattgttg gattagatcc attgactggc
     7381 tcgcctcagg cgagcaaaga ccctgtagaa ttcattctga tacacatgat aactagataa
     7441 tttgagatag actcgtctac ccgtttggac taatttccca gcaactttca gaaacttcaa
     7501 tcgaatagaa tgaatggtca ttcccttttg gacttcttca aagccaatcg ttcttaagaa
     7561 gttgactaag ttgtaagcta tcaagctgag catcattcgg acatgattct ccaaaaagcg
     7621 aggactgtct gttttgtcaa agtaaaagcc agctttcgct tctttaatga agttctccat
     7681 tgtgccacgt ttggcataga tagaaaagat ggtatcagga gaaacatttt ctgatagatt
     7741 cgtcacgata aattcatgtc gaaagagtag ttcgcccgct tcacgtgttg agcgtataca
     7801 cacgcgacga ctttgtgacc aggattgtgc ttgataagtg gtcgagaagt actgaacttc
     7861 tcgttcttcc cacttttgat tatcgccata aagtactgat ttctcagcta tttgacctag
     7921 tctacgatta ttcttcagtc gaataacata atgactcttt tttgattcac acgaatcata
     7981 cacaccaggt gtagcgaacc cgctgtctcc acgaaccaag atgtcagtgt ttggtagaga
     8041 gtgattatag tgctctaata aaggtgtgag aaactccttt acgccttttg atgtatattg
     8101 atttcctgaa cgtagttcag cttttaagaa gtcaccagtc aatccgtcaa aagctaccaa
     8161 tggatggtaa ccataggttt ggtagtgtgt attataattc gtttgttctt ggtgaccaaa
     8221 tgtatctgaa tgggtcgaat ctaaatcaat gattaattcc gtatcattac ggatgaggcg
     8281 tgctttatcg ataagttctt ggttcaaagc ttgaagttca tggatattct cctcagatag
     8341 tcgatctaaa aatcgggaaa gtgaagattg agaagcgagt tctttcctat ctaaaacagc
     8401 tttaaacaca ggatcttgtc tcaggagatt agctgcagaa tcagctgagt aaccagcaat
     8461 taattgcata atgaactgct caagtatgga taagttgtca tgagtaaaat acgctcgttc
     8521 gtcttcaatg tgaatgtgtt gcttagccag ttcagaaaaa ccaaagatgt tcatcagctc
     8581 tttcactagg acgagacccg aatcactcga taattgacca cctgtatgag aaatagtgat
     8641 atttgaattg aattttactt ggtttttgtg taagctagtc atgaaaagaa ctcctttctt
     8701 ttggttggtt tagtcacttt aaccatagca gaaaggggtt cttttttcat cacttaacgg
     8761 gtgaagatga aaaagtaatt gtaagctgcc gtgaggcagt ttcacatggt tttaattaaa
     8821 agtatgaatt attcaggcta tcattaattt tataaaaaaa attaaatgtt tttagcactg
     8881 ccatataaca ttcaaaacat tcttctatag ttggtttact tccttgagga gaatgaacca
     8941 atttattacg tttttctatg aaatttttaa tttcctttct tatttctttc ggaaactcaa
     9001 tattaaagta ccctttaaac atgctcccta ataatttgtc tacaggggga gattgtaaat
     9061 tctcaaatat tagagttaaa tcaggtttct cttgttgata aaattccttt acccctattt
     9121 cacaggctgt aattatcgaa ataaacctat ctctagtatt tgatatattt ttacttcttt
     9181 taaggagtat aagagaaaag gggatacttt cgtgtccatg catgtaatta actaattgtt
     9241 gagcttcaga agttatatct ctaattatat agttaacgga attaggaagt gtctttaact
     9301 ctaatgaaat ttctatccaa ttactatctt ctaatctgta tatgctcgaa gtataatttg
     9361 attcgtcagc aagcatcgct acatcccaaa cactgatcat aaaatctttt aaacgttcaa
     9421 tcatttcagc aatattgcta aaatcagcta atttttcttt agaataaaaa aaaacattta
     9481 tatcagaatc aataaattct atttttttat tactatatcg tcatcattat cttgaccatt
     9541 tatgtttatt gttccctgag tggggagtac ttctttcaaa ttcaagttaa atttatattc
     9601 cattacttct cctccaatat ataaaaatta cttaactgta tccaaattta atatgtaaat
     9661 aaatcattaa tttttagcta aattctatga gaagtttatt tttgttgttt ttgctaatta
     9721 actaaaacta gtacaaaaaa tttaaaatag attattaaac ctattgctta ttctattcag
     9781 tcatatatat aagcgtcatc ctttagtaac taacatccca cactacaata gtattataac
     9841 atatctattc aacttcaaat tgttgaaatt taagccattt atatttactt ttcctcaact
     9901 ttagaaatga ttttactaac cttatatccg taatacgcgt aacaaacaca ttcattaata
     9961 acaatcaaca ctaagctata ttagcttttt aaatgactag ggtaaataaa ataaggatca
    10021 aaaactttta agtttctgac cctttcctta cttccgattg gttaatagtg atcttttgca
    10081 gaataaataa atatcgtttc attttcaact ctatatatca gtctatgttc atctgtaatt
    10141 cttctggacc attttccaga taaatcatgc tttaatggct caggttttcc taatccagca
    10201 aagggggaac gatcgatatc ttttattaac ttgttaatct tttttatatt gcttttgttt
    10261 ccttgctcat gccaataaag ataatcatcc caagcatcat cagaccaagc cttaatcatc
    10321 agattcaacc tcgattaagt catgtgtttt aaatgcacct ttggagaatt gttcatctcc
    10381 tcgacgaatt ttttccatga cgtaattatt agaaagtgtt ctcaacgttt cttgcataga
    10441 atcataatct ctttttgata atacaacaac tgtatcttct acatctttac ttgttacaat
    10501 aagtgtttca gcatcctcat taacttgttt catataacta cgtaaatttt ggcggaaatt
    10561 tgaataagct actgcttcca ttcctttcac cccttattta tttctataaa acaattgtac
    10621 attatattgt acaattaagc aaatgattaa tattctaact tcttataatt aaaagtgcta
    10681 tcacttttag tttttaggat aaaaagtgac gtcacttttt gagtgctggt acctcaaatc
    10741 ctgctttttc ttgggcaatc aataaatcta acgcaataca cataatcctg gattcacttt
    10801 tgccgtactt ctgctttagt tgctgcaatt ctttttgtct cttttcatcc aacgtaacgg
    10861 gtaaccgttt atttcctatt gcaattggca ttagtactct ctcctttcat cgaaataacc
    10921 ctatgaaaaa tatggctgca atcatcttga atagtagact cacaagggct aatacaaagc
    10981 gccaaaagat caaacaaaat accagtattg ccaaaaatac tacgaagttt aaatgcacag
    11041 ctgcagcatg gcgcataagt atttcgccaa caaataggac taacaataga ggaatgattt
    11101 tattcatatg gatctccttc tttctcttag gttatcgggt gttgcccgct tatttcgcac
    11161 cacctaagcg gcgggggcgg ttggagcgat tggtgcgaaa taagaaccat tcccttagtt
    11221 actaggtttt ttgtccttat ttcacacatt ctcacttttc ggtataaatg attattgcct
    11281 ttttttcctt tcaaatcgtt gatatggcat tcgtttacgg tcaagttcat tttggatttc
    11341 ttctgtatcg tcgtaagtat aggtgtctaa aaaatcagtt aaagtcgtgt accagtcgtc
    11401 gcctgggtta tctacttctt ctacatattc cctcaaaaat gcttcgggta cagcgagttc
    11461 ataatccatt cccattaaca cgatagattc cgttccacac gtcaaaaatc tagtaaatac
    11521 aaggtaataa tcgtctatcg tcgcatcttt gctgtttagc tcttccattt cttcttccat
    11581 taattccatg ctctcaaaaa ttgaataata ttctgattct gagtaatagt gtttcctgca
    11641 aatcgtgtag ctgacaaagt tttcgaccag ctcactcctt tctaggtaaa cattcatgat
    11701 gtatttttct gtttctagtc gtagaagctc cgttcctttt tttaccgttt caggacgacg
    11761 tttatacacg tctaaacgat tatggctgac tgtgaccttc gtttgactcg tttcactttc
    11821 caaatacaat tgttcttc
//
LOCUS       DAYNVV010000075        11544 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.078, whole genome shotgun sequence.
ACCESSION   DAYNVV010000075 DAYNVV010000000
VERSION     DAYNVV010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11544
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.078"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            6..305
                     /locus_tag="ACGXWR_002417"
     CDS             6..305
                     /locus_tag="ACGXWR_002417"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFK0803934.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="ACGXWR_002418"
     CDS             378..1739
                     /locus_tag="ACGXWR_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFK0803935.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFLSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLLFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGILTMPIYLYGATYLAPILSDSAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="ACGXWR_002419"
     CDS             1761..2021
                     /locus_tag="ACGXWR_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803936.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="ACGXWR_002420"
     CDS             2035..2787
                     /locus_tag="ACGXWR_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HFK0803937.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="ACGXWR_002421"
     CDS             complement(2881..3486)
                     /locus_tag="ACGXWR_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFK0803938.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIEQAREWTDHLLTK"
     gene            complement(3542..4516)
                     /locus_tag="ACGXWR_002422"
     CDS             complement(3542..4516)
                     /locus_tag="ACGXWR_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HFK0803939.1"
                     /translation="MYTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DCPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4894..5613)
                     /locus_tag="ACGXWR_002423"
     CDS             complement(4894..5613)
                     /locus_tag="ACGXWR_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFK0803940.1"
                     /translation="MPKYEEIANILRERIRSKEYPPDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5740..7011)
                     /gene="celB"
                     /locus_tag="ACGXWR_002424"
     CDS             complement(5740..7011)
                     /gene="celB"
                     /locus_tag="ACGXWR_002424"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFK0803941.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7164..8561
                     /locus_tag="ACGXWR_002425"
     CDS             7164..8561
                     /locus_tag="ACGXWR_002425"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFK0803942.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWNHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSRLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKAIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGTIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8642..9082
                     /locus_tag="ACGXWR_002426"
     CDS             8642..9082
                     /locus_tag="ACGXWR_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFK0803943.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9229..9555
                     /locus_tag="ACGXWR_002427"
     CDS             9229..9555
                     /locus_tag="ACGXWR_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFK0803944.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9556..10305
                     /locus_tag="ACGXWR_002428"
     CDS             9556..10305
                     /locus_tag="ACGXWR_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HFK0803945.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10331..10741)
                     /locus_tag="ACGXWR_002429"
     CDS             complement(10331..10741)
                     /locus_tag="ACGXWR_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFK0803946.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNK"
     gene            11248..>11544
                     /locus_tag="ACGXWR_002430"
     CDS             11248..>11544
                     /locus_tag="ACGXWR_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0803947.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKER"
BASE COUNT         3697 a         2010 c         2365 g         3472 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttcgaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcctgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtctta ttgctgcttt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattacca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcctc acgatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgattcagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaaggaccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcaaaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgggagat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc tcgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccaatc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa aaatgaagta gcatgaagag
     3541 attattcacg ttttttattt gcatcacttg tatcgaaagg acggacatag gcttcaatgg
     3601 cttcacgacg ttcttctaag aatggaggaa gagatagttt ttctcctgct gattctgctg
     3661 gttcatcttc aaggaatcca ggacaatcag ttgctaattc aaacagtacg tgatgagcgg
     3721 ctaggaagta ctcagattgg aaatagaaac gatcgacgaa accagaattt ggcaattcaa
     3781 tcttattgat tacttgaatc cagtattcca atgcttcttt gtctgctaca cgcaatgcta
     3841 agtgatggat atttccaaat ccttcgattg cttttggcaa gtctgtccga tgttcaataa
     3901 tgatgcttgc accatttccg ccttcaccga tttcaaataa gtagaaatct cctgaatggt
     3961 ctgtttcttt gaatcctaag attttttcaa gaatcaagcg gatatgctct aattgactga
     4021 cacggacaaa gacaggtcca agtcctgtga tcgcaaactc tgtcggtaca ttgctgtttt
     4081 tccaaggaat gccagctgct acaccttgat tgttttcgtc agagatcaat tgataatact
     4141 gattatcgaa atcttcaaat tcgatatatt ttttgccgaa acgttcattg attgctgaat
     4201 gagtaacgtc atatttttca aaacgttcca accaaaagtc taatgctgcg tcacttggca
     4261 cacggaaaga agcacgagag atcgtatctg ttcctttttt tccttttggc tgatttggaa
     4321 aatcaaagaa agtcatatct gttcctggcg caccagtatc gtctgtaaag taaagatggt
     4381 aagtttcgat gtcatcttgg ttaactgttt ttttgattaa gcgcattcct aaaatatctg
     4441 taaaaaagcg gtagattttt gtagcgctag atgtcattgc tgtgacgtgg tgaattcctc
     4501 tgatttgtgt atacatgata aatttcctcc tgtcaactta caaaaagtaa gtagttgatt
     4561 tagacatagt atagagggtg catctctatt ttgcaattaa tttgtcttct aaagtatcag
     4621 gaaggaatca agaatggaaa agaggaggga cggatcaata aaataaaaag acttacgact
     4681 agctgtatcg atttcaaaaa aactagcttt aaaaagctaa ctttagaatc attacgggtg
     4741 gtcataagtc tttttatgct gagttatttt ttcatttttg agctaatgct taggatagga
     4801 tagaatgttg atttcacgat ctcttcttgt tacttgaaac tgcttactac tgtcacgatc
     4861 tcttggtaaa cggctttttc acaacctctt catttaagtt gaacgcacat ccagcacaga
     4921 atagttccga acatcaaatc ggtttcggct ggaagaatat tcaatcggct gtccatcttt
     4981 gagatagacg acttgctgaa cttccagtac aggatcgttt tctgcacagt tcaaatattg
     5041 ctgatcatat tcatcacttt tatctgcaga aatagcacga taagcccctg caaaatggac
     5101 attcaattct tgatgaagat gatcatagat agaggctaac aaatgttctt tttttaaacc
     5161 cggcacaaga tggactggca taaaagtatg ctctaaaaca tatggctcgc catctaagat
     5221 ccttaaccgg tgaatattgt agacaggttg ctcggcatcg atcatcaatc gttcttggat
     5281 atattgatta gggaattcaa catcaaaatg aatgatttga ctcttcaaag aacgatgtct
     5341 gcgtttcatt tggagactca aaccttcata ctcgttagcg ggcgatgtgt ctttttgcat
     5401 aaatggatga ttcaagattt tcgttcctga tcctcgctgc gaatagacaa gtccttccat
     5461 tgctaagata ttgatggctt ttttgattgt catccggctc gcaccaaatt ctttgaccaa
     5521 gtccacttga ttaggcaaaa aactatcggg aggatactct tttgaacgga tacgttctct
     5581 taaaatattt gcgatttctt cgtattttgg cacgttattc acctcttcta gagtataacg
     5641 aaagattatg cttccgacaa ctcgaagtag catctggaac attgtttatt cgaaaaaaga
     5701 ggtcgtgaca agtttttgtc acaacccctt aatgatctat taagcaatat ctaaatctgg
     5761 ttgtttatct agtactttca ggaatgggta ccagataaag gcaacgatga caaagtcgat
     5821 gacttgcagc ataccaccaa gccatgaatt tgttgctaag acaccgcttg caatgattgg
     5881 cacagtccat ggaacagaga cgccagttgg tgcagggaca agtccagcag ccattaccaa
     5941 ataattgaac gtcgttacga ttagaggtgc cacaacccaa ggaataagga ttgttgcatt
     6001 caatacgatc ggtagaccga agatcgctgg ttcatttaca ttgaaaatac caggtgctaa
     6061 agctaatcgt ccaacatcac gatactgttt ctttttaaga acaaaggcca tcaataaaac
     6121 gacagctaaa gtcattccag agccaccaat accaacagtg aaggtttcca tgaatggttt
     6181 tgtgatgatg tgtggtaatt cttttccatg ttgataagct tctaagttat caagcatcag
     6241 tgtattccaa atcgggtcca ttacagagtt gacgatgatt tgtccgtgaa gtccgaagaa
     6301 ccataagaat tggacaaaga acaaagcaat caatgttgca ggtaaactac ttcccaaacc
     6361 agttaatggt ttttggatca cttcataaac gacgtcatgt aagttagcat tgaaaatacc
     6421 agtcatcaca gcattgatta ctaagaaaat agttagtgtc actacagcag ggatcaaagc
     6481 ggcaaatgat tttgttactg caggcggaac tccatcaggc attttgatct gccagccgcg
     6541 tttcgtgatt ctgcagtaga tttctccagc caagaaagca gcgatcattc caatgaacat
     6601 tccttttgcg ccaagacgat caagtgaaag cacaccagtc acatcttcac cgccagcggt
     6661 tttcattgca aaaggcgtaa gaatcaagaa gctggcaaaa gacacggcac caccgaaaat
     6721 accttcaacg tcataagatt ttgataaata atagccgata ccaaaagtaa caaaaaccga
     6781 catgatgctc attgttgcat tttgcccatt accgaataag ttcgataaag ttccctttgt
     6841 tgcgtcactg aaaaaaggca agttattgat aacgacaacg atcgaaccga acatcgttaa
     6901 agggaaggaa agcatgaaag catcccgcag cactgtaagg taacgatttt gccctaataa
     6961 attagctaag ggcatgattt tctcagaaag cttgtccata aaaccgttca tttttattca
     7021 cctcaaattt atttgcaatc gattacatac aaagtataac gccaaaaatt ttaaatgtct
     7081 agtcattttc ataaaaagta ttgatttatt ttttagggtt cgttatgatt acgatatcaa
     7141 gaaaaaagag aggaagtaaa aaaatgaaaa cctacacatt cccagaaaat ttttggtggg
     7201 gttctgctgc tagcggaccg caaacagaag gaagagtaag tgatgatggt aaaggagaaa
     7261 atatttggaa tcattggtat gaattagagc ctgaaaaatt cttcgatcaa gtaggacctg
     7321 aaaaaacttc gcaagtttac acaaaataca aagaagatgt tcagttaatg aaagaaactg
     7381 gccataacac atttcgtaca tctatccaat ggagtcgttt gattccagaa gggacaggtg
     7441 aaatcaatca aaaagctgtt tctttttatc gagattattt tactgaattg ctggataatg
     7501 gtatcgaacc ttttgtgaac ctttaccatt tcgatatgcc actaccactg caagaaaaag
     7561 gcgggtggtt atcaagagaa acggtcgacg cttatgtttc ttatgcagca gcgtgctttg
     7621 aactgtttgg agatctggtc aaaaaatggt ttactcataa tgaaccaatc gtacctgtag
     7681 aaggaggcta cttgtatcaa ttccactatc caaatcatat caatatgaaa gaagcggtcc
     7741 aagtaggcta tcatgagaat ctagcaagcg caaaggcaat caaagcctac catgaaggcg
     7801 gacatgatgg tgagatcgga atcatcttga atctgacacc aagctatccg agagatgaaa
     7861 cgaacccaga agatgtaaaa gcggcgaaga tcgctgacgc attcttcaac cgatcattcc
     7921 ttgaccctgc agtgaaagga gagtttccac aagagttgat cgaaattgtc aaagaattgg
     7981 ctataatgcc agagatccat gaaggagacc tagaactcat ccgtgaaaac acgattgacc
     8041 tgctaggaat caattactat cagcctcgtc gaatcaaagc aaaagaaact ccaatcaatc
     8101 acgaacatag ccccatgcca gatgattatt ttgataatta cgacatgccc aataaaaaaa
     8161 tgaatccata tcgtggatgg gaaatttacg aaaaaggaat ctatgatatt ttaacgaata
     8221 caagagaaaa ctatggtaat atcaaatgct atatttctga aaatgggatg ggggtcgaag
     8281 gagaagaacg atttgttaac agcgaaggaa ctattgaaga tgattaccgg attgagtttg
     8341 ttacggatca tttgaaatac gtccatcaag caatccaaga aggaaccaat tgtgtgggtt
     8401 accacatgtg gacatgtatg gacaactggt cttggacaaa tgcttataag aatcgctatg
     8461 gctttatcgc tgttgatttg gcacaagacg gtaaacggac gatcaaaaaa tcaggtcgct
     8521 ggtttaaaac ggtctctgaa aaaaacggat ttgatgcctg atattttttg ataaaacgtt
     8581 cacaaaatgt ttgttctaac actgtaatcg tgctacacta acagtgaagg aggcgtttac
     8641 aatggtagat acttatcgta atattttagt agcaattgat ggttctgaaa aggcagaaaa
     8701 agcatttctt gaggcaatca cgattgccaa acgaaatcag gcaacgttgc acatcctgta
     8761 tgtcaatgaa gtaacaggca attactttgg tgattttgca tttgttacaa caagccttca
     8821 ggaagaattg gatgaggttg cggaaaacca gatgaaagaa catcgaaact tggcaattga
     8881 aaaaggcttg acagatatcg agacatatgt tctttacggt tatccaaaga cactgattgc
     8941 taatttccat gaatcgaaag aaccaatcga tctgattgtc atgggggcga caggtctgaa
     9001 tgcggtagaa cgtgcactag taggttccac tacttcctat gtagtcaacc acgcatcatg
     9061 taacgtcatg gttgtaaaat aaataaatta agggaacaga aagcaaaaaa gcataacgct
     9121 tcttttgctt tctgttcctt taattttttg taaaaaatta ctttacctga tgaagtaatc
     9181 atgctattct aattacaacg acagatggag taatatggag gaaagaaaat gatttcaagt
     9241 gatggaatac gcggatacaa tgatgcgatt attttatcga tccttaacaa aaacgattct
     9301 tatggatatg aaatttctaa aacgattcgt gagaggacaa atgattccta tgtgatcaaa
     9361 gagacaacac tttactccgt ttttgcccgt ttagaaaaga atcaactgat tgtttcgtat
     9421 cctggagaag tgactcatgg aaaaaagcgg acatattata aaatcactga aatagggcgt
     9481 aatcttttag aagaaaaaaa gcaagagtgg ctgacgacga aagacgtagt cgatcaattt
     9541 ttggagggaa attaaatgga tacaatccgt aattatttag acagtctttt tatcggagta
     9601 cctcaaagta ccgagataga taagctgaaa actgatttgt tggcaaatat ggaagaccat
     9661 tatcatgaat tgatgggaga aggaaaaaat gaacaggagg ccatcggtac agtaatttcg
     9721 acatttggtt caatcgatga attattagaa gaactagatg tcgaaaaaaa acatcaagct
     9781 gacgagacgg aaacaaacac agcttctatt tatttaagcg aagcagaaaa ctactggaaa
     9841 gaatacagag cggcaagtct ccaagtggca tcaggtgttc tattcattag cttatctttt
     9901 gcaagttttc ttttcttttg ttcagcaggg tatgtgttca tgggtatttc ttgtctgatt
     9961 ttcggtatag cattagctgt cggttttttt attgcttctg gtatgaaaat cacacgttta
    10021 aatcactttt tgcaccatcg gaaaatacct gaaaaagtat tagcagaagc aaaagaaaaa
    10081 gaagaagagt atcagcgaag ttttggcttc tcactgattg caggaattgg attatgtatt
    10141 ttttcacttt tcccactttt ggcttcttta atgtggtata tggatggtag tatcggtgcc
    10201 tctatatttt ttgttacggt aggaacggga gtcttcttga tcatttatgg cagtctggtc
    10261 cgtcattctt atcgtcaatt cactcaaagt gcttattact ggtgaatgta ttcagatttg
    10321 taaaaatatt ttatttattg cttacccatg taaaatcgtt atagacagat ttcagttgac
    10381 ttctgcgcca ttgtacaggg ataaaaagac gcatactatc ttcattgaat ccgactaata
    10441 atttctttcc gtcagtaatg atgggacgtt gtaacaaagt aaaatgcgag acgatcagat
    10501 cgacaagctc tgaggtcgta cattggtcga tttgatcttt caaattttta taatcaatcg
    10561 agcgtttagc taatagatcg tcaaatccgt tttctgttaa tgacaataaa taaaatatct
    10621 ctttccttgt taaaggctgt ttaggtgtga aaattcgttc tctgtaaggc atttgatggt
    10681 ctttcagcca gtttgccatc agatggtaac tatgtgtgcg agaagaatag atcgtaagca
    10741 taaaaaaact ccttaaatag tccattaatt tgttagatct gttgagataa ataataggta
    10801 aggagctgtg cataagcatt gatcaaaaca acccaaacat cattagaaat aactttctaa
    10861 agtcttaaac ttgcgacgag aaacaactag actaatagaa aaaatgtctt agccatttgg
    10921 cttcctgttt gtttttttgc ttatgctgca gctcctcggg aaagggttct aacaatttga
    10981 agaaggttga tgattgatct agtttaaatt gtgtgaaatt tgaaatctgg tgtttttact
    11041 agatgaatca cctaacaact atgattataa cttatagaac ttctgttttg tacttggttt
    11101 tgttatagtt gttataaagt tttattttat tacagaacat ttttaattaa tcgcgaattg
    11161 taaaattaag ttagaaaaat aaaaaggcat ttatggtaca ctcaaattgt atttccgacg
    11221 aaagaaaaca aaggagtgta accataaatg acctacaaac atcttaccat agacgaactg
    11281 acaatgatag aatcatatta tcttcaacat aataagccgg ttgaaatcgc taaccgaatg
    11341 ggacgtgcta tacaaactat ttataatgta gtcaataagt tcaagcaagg caagactgct
    11401 cttgattatt ggcaccagta taaagaaaat aagaaaaaat gtggtagaaa agtcattcaa
    11461 ttacctgctc atgaagtaga ttacattaaa gagaaagtca ctcttggttg gacgcctgac
    11521 gtcattatcg ggcgaaaaga aagg
//
LOCUS       DAYNVV010000076        11382 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.079, whole genome shotgun sequence.
ACCESSION   DAYNVV010000076 DAYNVV010000000
VERSION     DAYNVV010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11382
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.079"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(296..903)
                     /locus_tag="ACGXWR_002431"
                     /pseudo
     CDS             complement(296..903)
                     /locus_tag="ACGXWR_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313657.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
     gene            1426..2100
                     /locus_tag="ACGXWR_002432"
                     /pseudo
     CDS             1426..2100
                     /locus_tag="ACGXWR_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            2093..2254
                     /locus_tag="ACGXWR_002433"
     CDS             2093..2254
                     /locus_tag="ACGXWR_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803948.1"
                     /translation="MTEKEQVQQIVKKYNKSIADLSENASAKEFKTVMNYVADEANRK
                     QRKLVGLDK"
     gene            2738..3334
                     /locus_tag="ACGXWR_002434"
     CDS             2738..3334
                     /locus_tag="ACGXWR_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HFK0803949.1"
                     /translation="MNPTLITKKELLKKLDISTGVLANLIRNGMPKEGEMFNLDKIIT
                     WRENWSKNILGELEVGRVYTNKEISEKFKCSKQGGMRRSHQTNTLVLFSDQTGSNVYK
                     DKWLNGILQYTGMGLKGDQVLDKNQNKVLANSKSNFVKIHLFETFKPKEHTYLGEVYL
                     AGQIYTVNEKDSSGNSRKVYKFPLALINQEQLIEDKDI"
     gene            3315..3761
                     /locus_tag="ACGXWR_002435"
     CDS             3315..3761
                     /locus_tag="ACGXWR_002435"
                     /inference="COORDINATES: protein motif:HMM:NF013964.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFK0803950.1"
                     /translation="MKIKIYNQEENQTRHIRNLSNAKLEEEARKVSNYNKKMAAKYVN
                     EEEFCFSKTKIYKRNPFVSEYVKRLAKGICQLCQEKGPFIKDGVPYLHCHHIEYLSQG
                     GKDVIENCIALCPNCHARIHELELPDDKEKLLKIVEKRENSFSKIP"
     gene            4104..4427
                     /gene="relB"
                     /locus_tag="ACGXWR_002436"
     CDS             4104..4427
                     /gene="relB"
                     /locus_tag="ACGXWR_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HFK0803951.1"
                     /translation="MRFFKRGNYRAMITVRVSDAKKEWLSYMAEFYGITLSELLKNYS
                     MEQLEDEYNRQTAEIAHKHWIRSGKTTVFMEESLMNLVGWNDLPFKIHARNSEAALIG
                     KYVYW"
     gene            4747..4974
                     /locus_tag="ACGXWR_002437"
     CDS             4747..4974
                     /locus_tag="ACGXWR_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HFK0803952.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            4990..6156
                     /gene="hemW"
                     /locus_tag="ACGXWR_002438"
     CDS             4990..6156
                     /gene="hemW"
                     /locus_tag="ACGXWR_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HFK0803953.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDHETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            6391..7434
                     /gene="hrcA"
                     /locus_tag="ACGXWR_002439"
     CDS             6391..7434
                     /gene="hrcA"
                     /locus_tag="ACGXWR_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HFK0803954.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            7528..8091
                     /gene="grpE"
                     /locus_tag="ACGXWR_002440"
     CDS             7528..8091
                     /gene="grpE"
                     /locus_tag="ACGXWR_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HFK0803955.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            8142..9971
                     /gene="dnaK"
                     /locus_tag="ACGXWR_002441"
     CDS             8142..9971
                     /gene="dnaK"
                     /locus_tag="ACGXWR_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HFK0803956.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            10122..11288
                     /gene="dnaJ"
                     /locus_tag="ACGXWR_002442"
     CDS             10122..11288
                     /gene="dnaJ"
                     /locus_tag="ACGXWR_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HFK0803957.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
BASE COUNT         4002 a         1830 c         2328 g         3222 t
ORIGIN      
        1 agagattggc gcagcgaatc cttgataatg agctcggatg tgctaacgct agcgaggcag
       61 tctaacttta actgttagct cctgccgaag atcgtcacat ccgaggaggc tcattgtcaa
      121 ggacaatcgg aatagcatac ggaaagaagt tctgcacctt ataaaatttg tcaaaaaaac
      181 tgttgccatt ccatctatga atataaatag agtgtatctt ctttgataaa tgtcagaaaa
      241 agtgtgacaa ataaccatca gtaaaattac ttgtcatact attgataagg agtatttaat
      301 tgaagagaat gattaggaga aaggatctcc gtacttttta tagtaatcat agaatccaag
      361 tttgtataga cgaatctttt tttctcttat ttcttctgtt tcaaaatgga ctgcttgaag
      421 aatcaagtct gtgaattcta taggagctgt tccattcgca gtaatcaaat tacgatcttt
      481 cacagcttgt tgttctataa aatcttcttt attctgataa ttttccgatt ctaaccaagg
      541 aaattgcgca tttccggtgt gtttgtaacc ttgcaataat ccgctctgag ctaaataatc
      601 aactgcccca caaatagcag ctactggtac gtctgttttt aacaatttat cgattatttg
      661 atataaatga tgatttttta tgtcccatga attgccaccg atcataataa aaaggtcaac
      721 tttttcaggt atttgttcga ttaagtaatc gatttttgtt tttaatcctc caatggaagt
      781 gacctctgat tggatagaag cagttttgtt ttgccatccc tctttttggt ttagtgtgct
      841 agtaatataa gcaccttccc aatcggcata ttcctctaat agaaacgtaa tcgcagtttt
      901 cattttcaag ctctccttta ctatctatga caaggacaac agttttaaca tacagacatt
      961 cattaaattt ggatagcgac agcgaaaaca acaattctta agttttagac agagtataca
     1021 gacagtcaac ttaattaaat acgaactaaa taaaaatgac aggtaatcat ttttgtttac
     1081 cagcattata acattttgca tacatggatg acaaaagaac caattcccac ttgcttgagt
     1141 acaatcttaa aagaaactgg aaggcaaaaa gtaattatag aaacgaaaaa taaatcatat
     1201 cgggcactca gacatgaaaa caaccctaga aatatataac tagtccaatg aaaaaaaagc
     1261 gaatgccgta gaaaacaagg attctgcgta cattcatatc tcattttgcg agcatatctg
     1321 ctattactgt gactaaatgt taatatggtt aaaatgaccg ttatattttt tatataaata
     1381 tcgtataatt agtatgaata tagaagaagg aaagaaggtg caatcttgga acctaaagac
     1441 aagtatttag attacgctag ggtcaataaa gataaattta ttgaaacaat catcaaggga
     1501 aaaatccctg atgatgaaaa agatgcggta ttcatggctg gaagcccagg agcaggtaaa
     1561 acagaggttg cactaggttt agcttaaaat tatgacaacc atgttgtgat tgatgcggac
     1621 tattttagag cacaatttcc agaatacaat ggaaagaact caagtgtttt tcagaaagct
     1681 tcttcttggt tagttgaaca atcattaaaa tatgtactgg aacatggcta ttctttcata
     1741 ctagaggata cttttgctat ccttagtgca gagaaaaata ttattcgagc ccttaaaaat
     1801 aactttcgcg ttacgatttt ctatgtttac caagatccca aagttgcctg ggatttcact
     1861 cgaaaacgtg aactagctga aggacgtcat gtgccaaaag aaatgtttat caatgcgttt
     1921 tttaagtcca gagagaatat tgaaaaagtc aaaaatagac atcctgaagt agtccttcac
     1981 ataatgatta aggattatca aaacgacatt tctgaagtgc attatgcagc agataatatt
     2041 caattagtac taccaataca atatacttca aaagagttgg aggaggaatt acatgactga
     2101 gaaagaacaa gtacaacaaa tcgtgaagaa gtataataaa agtatcgctg atttatcaga
     2161 aaacgcctca gcgaaagaat ttaaaacagt aatgaattac gtagcagatg aagcaaatcg
     2221 taagcagcga aaactagttg ggttggataa ataaattttt taaaccatat ccttgtaaag
     2281 ttgagttttt tattttaatg aattaagact attaaataga taattattgt aacttaaaaa
     2341 acacagctaa aaattagttg tgttttttat taggtttact tttctggtat aaaaggaact
     2401 agctactttt tcaaaatttc taaatcattc aatatgtagc gcttactaaa ttattcgcca
     2461 taaaatttta taattggatc actcattgtt ttacctaagt catatttaag taataaccgg
     2521 tgtttttaca taagaagact tcgggtattt tttagtttga ttagctctga tatacctata
     2581 aagaatatgc taaggtaaga atagtaaaaa ttcacataga tgaggtataa taatgatatt
     2641 tttatatatt acagataact tgacacaaaa tgagtttttt tcgatttttc aagttatcta
     2701 atgcaattat attgatatca ttaggagctg cattgttatg aatccaacat tgattactaa
     2761 gaaagaatta ctaaaaaaat tagatatttc tactggtgta ttagctaatt taattagaaa
     2821 tggcatgcca aaagagggag aaatgtttaa tcttgataag attattacat ggcgagaaaa
     2881 ttggtctaaa aacatattag gtgagttaga agttggtaga gtatatacta acaaagaaat
     2941 ttcagagaag tttaaatgtt ccaaacaggg tggaatgaga agatctcatc aaactaatac
     3001 tcttgtactg tttagtgatc aaacaggaag taatgtttat aaagataagt ggttaaatgg
     3061 tattttacaa tataccggta tggggctaaa aggggatcaa gtattggata agaatcaaaa
     3121 taaagtttta gccaattcaa aaagtaattt tgtaaagatt catttatttg aaacatttaa
     3181 accaaaagaa cacacatatc tgggagaagt atatttagca ggacaaatat atactgttaa
     3241 tgaaaaagat agttcgggca acagcagaaa agtatataaa tttccattag ctttaataaa
     3301 tcaagagcaa ttgattgaag ataaagatat ataaccagga agaaaatcaa actagacata
     3361 ttcgtaattt atctaatgct aaattagagg aagaagcaag aaaagttagt aattataata
     3421 aaaaaatggc tgcaaaatat gttaacgaag aggagttttg cttctcaaaa acaaaaatat
     3481 ataaacgtaa tcccttcgta tctgaatatg ttaaacgact tgcaaaaggt atttgtcaac
     3541 tttgccaaga aaaagggcca tttataaaag acggtgtacc ttatttacat tgtcatcata
     3601 tagaatattt gtcgcaaggt ggaaaagatg tgattgaaaa ctgtatcgcg ttatgtccca
     3661 attgtcatgc tagaattcat gaacttgagt tacctgacga taaagaaaaa ttgctgaaga
     3721 tcgttgaaaa aagagaaaat agcttttcta aaataccgta atttattttt ataggacaaa
     3781 taagctaatg tgagctatgc cttctatata agactaagtt ctattataag taacgaagta
     3841 attctcgttc cttcctgtag taatattttt taaataacct ataggcttct tcaaaagtac
     3901 atcctccagt aaattctaag tactggagga ttctttttct agtgttgctt tactcatgaa
     3961 aaagtagttg gctacttcat caaaatttct gaactttttt aatgtataat aaagagctcg
     4021 atcatttact acaaggatgc tagctcctac attttcacag ttttttagca agtaaatttt
     4081 tctaaaatca catcaggaaa tgcatgagat tctttaagag aggcaattat agggctatga
     4141 ttacggttcg tgtaagtgac gccaaaaaag aatggctttc ttatatggct gaattttatg
     4201 ggattacttt atctgaactt ctaaaaaact attcgatgga acaactagaa gatgaataca
     4261 atcgtcaaac ggctgaaatt gcccataaac attggataag aagtgggaaa acaacagtat
     4321 tcatggaaga atccttaatg aatttggtgg gctggaatga cctgccgttt aaaattcacg
     4381 cccgaaattc agaagcagct ctgattggca aatacgtgta ttggtagaga tagaagataa
     4441 tcaattcgtt gttatcgcta ttcaagtagg gcaccgaaga aatgtctatg attaagagac
     4501 tgtttatttt tacaaaaaaa taataattgg aatctagtta aaactcttga agtgagagat
     4561 ttgactagat ttttttatga ataaaataag gacaaaattg tttaggaaga atcatgagtg
     4621 taaaaaaatc atccaagaag tcgattcttg gattttttag tggatttgtt cgccaaatac
     4681 gtttagtatg cgtatatgag aggttgtaag caaagcgttg tggtctgagc acttaaggag
     4741 gaatctgtga aaatagcttt tcatattttt gcagattttg acttaatgcc gaaggtcagc
     4801 tttgcgatta ccgtttatcg agaggctgta aaagcaccgt gtagctccga tgacaataag
     4861 caagcatttt tagagctagg tttccttgat tctaaatatg cggcttattt caatgagttg
     4921 gtgcttgaac gcgattttaa gaaggtcgaa aacaggcacg acttttcgac gtaaggagaa
     4981 agaatttcaa tgatagaaac aataaatccc gcagaaaaca aggtttctgc gtacattcat
     5041 atcccatttt gcgagcatat ctgctattac tgtgacttta ataaagtttt tttagaaggg
     5101 cagccagtag atgagtatgt ggaaatgctg ctgaatgaaa tgagattaat gctggaaagt
     5161 catcctacag cgaatttgga aacactttat gtaggaggcg gaacaccaac ttctttatct
     5221 gctaaacaac ttgatcgact attatcaggt gctagagaga tcctgccttt tcaaaatggt
     5281 aatgagttta ctgtagaagc gaatcctggt gatttgaccc gtgaaaaact tcaagtgatg
     5341 aaaaactatg gcgtcaatcg tttatccatg ggagtgcaga catttgacaa tcgcttattg
     5401 aaaaaaattg gacgtaaaca tactgcagaa gatgtgtatc aaacaatgca atttttagaa
     5461 gcagaaaatt ttaccaatgt aagcatcgat ttgatttatg cattaccggg acaaacacta
     5521 gaaggatatc gggatacttt ggaaaaagct ttggctttgg atctgcctca ctattctttg
     5581 tactcattga tcctcgaaaa caaaacaatg ttcatgaact gggtacgaca aggaagactc
     5641 gaactgcctg atcatgaaac ggaaaccaga atgtttgaag agacgattga agcaatggaa
     5701 aagcatggac gtcaccaata tgaaataagt aactttgggc tctccggaca tgaatctcaa
     5761 cataacctca tgtactggaa caatgaccac tattttgggt ttggagctgg tgctagcggt
     5821 tatcttggag atattcgtta ccgcaacaaa ggaccaatcc aacactattt acgcccatta
     5881 cgagcaaatg aacgcccggt attggaagaa gaaaaattga cacgaaaaaa tcaaatagaa
     5941 gaagaaatgt tcttaggact aagaaaaaaa acagggatta ctaaaaaaca tttctatgat
     6001 cgctatcaaa aaacaattga atcggtgtac ggtgatgtgc taagggaatt agagcaagaa
     6061 gggttacttg ttaatgaaga agaccgtgtt tatttgacac caagagggac ttttttgggg
     6121 aacaatgtgt ttgagcgctt tttatttgaa aaatagtttg aagaatattt gttttttatc
     6181 gaaacttgaa aagaaaaagt ttagaaagtt tgacaatgag gtattgaagt attgatataa
     6241 ctggatttac atcaattatt tagaattagc actcttgtgt ttagagtgct aaaaaatgga
     6301 gtctttctct tgacaggaga agggcttctt gctatattta taagtgaatt agcacttaga
     6361 atatatgagt gctaatgaga ggtgaggaag atgttaacaa agcgacaaaa cgacatttta
     6421 cgtctgatca tccaacacta tacgagtagt ggcgtgcccg ttggttccaa aacattaatg
     6481 tctgagggag tcaaggccag ctcagcaacg attcgcaatg atatgaaagc attagaagat
     6541 gaaggattgc tgttgaagac tcactcttct tctgggcgga ttccatctgc tttaggctat
     6601 cgttattacg tggatcattt gttaaaacct gctcgcgtag cagaagatga tttgctgctg
     6661 attcgtcagt ctctaggcag agaatttcat gaaatcaatg agattattaa gcaatctgct
     6721 gagatattat ctgagctgac aagctatacg actttttcat tgggacctga aataaaagac
     6781 cgccgactga ctggctttcg tatcgtaccc ttgaataatc gacagattat tgctatcgtc
     6841 gtaacagata tggggaatgt agaaagccaa gtgttcactc ttcccgaata tatgggaagt
     6901 caggaactag aaaaaatggt acagattgta aacgaccgtc tagtcggaga tcctctgatg
     6961 acggtgtacc ataaacttcg tacggagatt ccgatgattc ttcataaata tttccagacg
     7021 acagaaggga tgtctcagtt atttgacacc gttcttggtc atgtttttga agaaaaggtt
     7081 tatgtcagtg gacaaatgaa tctcttggat tatgagcccc gtcaagatct tgatcagttc
     7141 aaatcgatgt tttcttttat gaaagactca gacggactta cacaaatgat cactccgatg
     7201 gatagcaata ttcatatcaa gattggtgct gaattaggca atgatttatt gcagaatatg
     7261 agtatgattc aagcaagtta cgagatagat ggtcatggaa gaggtacaat agccttgtta
     7321 gggcctacta gtatgcctta ttctcggatg ttcggtctag tcgatgttta tcgaagagaa
     7381 ctagcagcta aacttgctga ttactaccgc tcgcttgact tgtcaaactc gtaatgtgaa
     7441 taacgaagct atttgcagct gatcgttctc tctttcttag taagagcaat caaacagctg
     7501 actgaataat gaaaggaaga ctgtatcgtg aaagaaaatc aagaagaact agataaagaa
     7561 atgacagatg ctcagccaga accggaaatc gatgtcgaag ctgcagaaga ttcgggtatt
     7621 tcagaagctg aagcggaaga attcgaaaca gcgaaattaa aagctgagtt agaagaaatg
     7681 gaagataaat acttgcgggc tcgtgctgaa atcgcaaata tggcaaatcg aggaaaaaat
     7741 gagcgtgagc aattacaaaa ataccgttca caagatttag ccaaaaaatt acttccatca
     7801 attgacaacc tggaacgtgc attagccaca gaagtgtcag atgatcaagg ggcaggtttg
     7861 aaaaaaggcg tggaaatggt cttggaaagt ttgcgtaacg cactggaaga agaaggaatt
     7921 gaaaaaatcc ctgctaaagg agaagccttt gatcctaatc ttcatcaagc agtacaaact
     7981 gttccagcga ctgaagatac accagccgat acgattgtag aagtactaca agaaggctac
     8041 aaattacatg atcgcgtgtt aagaccaact atggtcattg ttgcacaata attgtgcgga
     8101 tataaaactt acactttcaa ttaaagaagg agacgttaat tatgagtaaa attatcggta
     8161 ttgacttagg tacgactaac tctgcagtag cagtattgga aggaaacgaa gcaaaaatca
     8221 tcgctaaccc agaaggaaac cgtacaacac cttctgttgt atcattcaaa aatggagaaa
     8281 tccaagtagg ggaagttgca aaacgtcaag ctgtgacaaa cccaaatacg atttcatcaa
     8341 tcaaacgcca tatcggtgaa gcaggttaca aagtagatgt agaaggtaaa tcatatacac
     8401 cacaagaaat ctcagcaatg atccttcaat atatcaaagg attcgcagaa gactatttag
     8461 gtgaaaaagt cgaaaaagca gttatcactg tgccagctta ctttaatgat gcacaacgtc
     8521 aagcaacaaa agatgctggt aagatcgctg gtctagaagt agaacgtatc gtcaatgaac
     8581 caactgcagc tgctcttgcc tatggtttag ataaaacaga tcgcgacgaa aaaatcttag
     8641 tattcgacct tggtggcggt acttttgacg tatctatcct tgaactagga gacggtgtct
     8701 ttgatgtatt gtcaacagct ggcgacaacc atctaggtgg ggacgacttt gataacaaaa
     8761 tcatcgacta catggtagca gaattcaaaa aagaaaacag cattgacttg tctcaagaca
     8821 aaatggcttt acaacgcttg aaagacgctg ctgaaaaagc gaaaaaagat ttatctggcg
     8881 tatcaagcac acaaatcagc ttgccattta tcacagcagg agaatctgga ccattgcatt
     8941 tggaaatgac attgacacgt gcaaaatttg atgaattaac agctgactta gtagaacgta
     9001 caaaagtacc agtacgtcaa gcgttaaaag atgcaggtct gtcacaatca gaaatcgacg
     9061 aagttatttt agtcggtgga tctactcgta tccctgcagt tgtagaagca gtacgtaaag
     9121 aaacaggaaa agaaccaaac aaatcagtta accctgatga agtagttgct atgggtgctg
     9181 ctatccaagg tggcgtgatc actggtgatg tgaaagatgt tgttttactt gacgttacac
     9241 cattgtcatt aggtatcgaa acaatgggtg gagtgttcac taaattgatt gaccgcaata
     9301 caacgattcc aacaagtaaa tcacaagtat tctcaactgc ggcagataat caaccagcag
     9361 tagacatcca tgtattacaa ggtgaacgcc caatggctgc tgacaacaaa actctaggaa
     9421 gattccaatt gacagatatt ccagcagctc ctcgtggtat tccacaaatc gaagtaacat
     9481 tcgatattga taaaaacggg attgtaaatg tatctgcgaa agatctaggt acacaaaaag
     9541 aacaaaaaat cacgatcaaa tcttcttcag gtctaacaga cgaagaaatc gaacgtatgg
     9601 tgaaagatgc agaagcaaac gctgaagcag ataaagctcg taaagaggaa gttgacctac
     9661 gtaatgatgt agacgcattg ctattctctg tggacaaaac attgaaagaa ttagaaggca
     9721 aagtggacga agaagaagtg aaaaaagcag aaacagctcg tgacgaatta aaagccgctg
     9781 ttgaagcaaa caacatcgag gaaatgaaaa ctaaacgcga tgcattgaac gaaatcgttc
     9841 aaaacttgac tgttaaacta tacgaacaag ctgcacaaca acaagctcaa gaaaatccag
     9901 aagcagctca aggcggagca gatgatgtcg ttgatgctga ttttgaagaa gtcgatggcg
     9961 acgataaata atcagttcac tgaatttcga gagaaggcca aagttgctac tttggctttt
    10021 tcttttgaaa aatagtttga agtatcggtt tttgtttcaa acaaaatatg atatgataac
    10081 aagcgacgtg aaaatgatga gaaccaatag gaggaaagcc tatggcaaca aaacgtgatt
    10141 attatgaagt cttagggctc tcaaaaggag catcagaaga tgaaataaag aaagcttatc
    10201 gtaagctttc gaaaaaatac catcctgaca tcaataaaga acctgatgcg gaagaaaaat
    10261 tcaaagaagt atcagaagca tatgagattt taagtgaccc gcaaaaacgc gctgcatacg
    10321 accaatacgg gcatgcaggc acagatccaa attacggtgc tggtggagct ggtggcggat
    10381 ttggtggatt cggcggcttc tctggtggcg gcttcggtgg ttttgaagat atcttcgact
    10441 ctttctttgg aggaggcggt cggtcagtcg atccaaatgc gcctcgtcaa ggtgctgatt
    10501 tgcaatatac ggtcgacttg tcttttgaag aagcgatttt tggtgtagaa aaagaaatca
    10561 agtataatcg ggaagaaatc tgtcatactt gtggtggaaa cggtgcaaaa ccaggcacac
    10621 aaccaactac ttgtcataaa tgtcatggtg caggtacgat caatgtagaa cgccaaacgc
    10681 cacttggacg agtgatgagc cgtcaaactt gtgatgtttg tcatggcaca gggaaagaaa
    10741 tcaaagaacc ttgtccaacc tgtcatggct caggacatga gaagaaagca cattcagtta
    10801 aagtgaatgt accagctggt gtagaagaag gacaacaaat gcgtttagct ggtcaaggag
    10861 aagctggaga aaacggcgga ccatttggtg atttgtatgt ggtttttcgt gtagaagaaa
    10921 gtgatatctt tgatcgtgaa ggttctgaaa tttactatga attgccttta agttttgtac
    10981 aagcagcttt gggggatgaa gtccaagtac caactgtcca tggagatgtg aaattgaaga
    11041 tccctgctgg aacacagaca ggtacgaact tccgtttacg tggaaaaggc gctccgaagt
    11101 tacgtggtgg tgcaacaggc gaccaacatg tcaaagtaaa actgatcaca ccgaaaaatc
    11161 taaatgaaca acaaagagaa gcattacgtg cattcgctga agctggcggc atcaaagttg
    11221 aagaacagca agaagacggt ttcttcgata agtttaaaga tgcttttggc gggaaaaagc
    11281 ggaagtagtt tttctagtaa aaatataaag tagacttgcc caaattttct atttctagta
    11341 aaaacgctaa gtcattaata attaaaaacc agacgaacaa tc
//
LOCUS       DAYNVV010000077        11381 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.080, whole genome shotgun sequence.
ACCESSION   DAYNVV010000077 DAYNVV010000000
VERSION     DAYNVV010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.080"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(1..460)
                     /locus_tag="ACGXWR_002443"
                     /pseudo
     CDS             complement(1..460)
                     /locus_tag="ACGXWR_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
     gene            complement(712..1071)
                     /gene="rplT"
                     /locus_tag="ACGXWR_002444"
     CDS             complement(712..1071)
                     /gene="rplT"
                     /locus_tag="ACGXWR_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HFK0803958.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(1124..1324)
                     /gene="rpmI"
                     /locus_tag="ACGXWR_002445"
     CDS             complement(1124..1324)
                     /gene="rpmI"
                     /locus_tag="ACGXWR_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HFK0803959.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(1396..1920)
                     /gene="infC"
                     /locus_tag="ACGXWR_002446"
     CDS             complement(1396..1920)
                     /gene="infC"
                     /locus_tag="ACGXWR_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HFK0803960.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(1964..2089)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            2240..2872
                     /locus_tag="ACGXWR_002447"
     CDS             2240..2872
                     /locus_tag="ACGXWR_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFK0803961.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGNQSYLDAKN
                     MVLRESHIQKLTMQKTGLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTTIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(2874..3779)
                     /locus_tag="ACGXWR_002448"
     CDS             complement(2874..3779)
                     /locus_tag="ACGXWR_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFK0803962.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWEIALIISLVLSIWMLIALWRRIR"
     gene            complement(3864..4523)
                     /locus_tag="ACGXWR_002449"
     CDS             complement(3864..4523)
                     /locus_tag="ACGXWR_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFK0803963.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     CVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVS
                     I"
     gene            4839..5783
                     /gene="mvk"
                     /locus_tag="ACGXWR_002450"
     CDS             4839..5783
                     /gene="mvk"
                     /locus_tag="ACGXWR_002450"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HFK0803964.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            5776..6753
                     /gene="mvaD"
                     /locus_tag="ACGXWR_002451"
     CDS             5776..6753
                     /gene="mvaD"
                     /locus_tag="ACGXWR_002451"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HFK0803965.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKKGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            6766..7851
                     /locus_tag="ACGXWR_002452"
     CDS             6766..7851
                     /locus_tag="ACGXWR_002452"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HFK0803966.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            7848..8912
                     /gene="fni"
                     /locus_tag="ACGXWR_002453"
     CDS             7848..8912
                     /gene="fni"
                     /locus_tag="ACGXWR_002453"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HFK0803967.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKDPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAQEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(9161..9964)
                     /locus_tag="ACGXWR_002454"
     CDS             complement(9161..9964)
                     /locus_tag="ACGXWR_002454"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HFK0803968.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIRDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(9984..10307)
                     /locus_tag="ACGXWR_002455"
                     /pseudo
     CDS             complement(9984..10307)
                     /locus_tag="ACGXWR_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
     gene            complement(10340..10477)
                     /locus_tag="ACGXWR_002456"
                     /pseudo
     CDS             complement(10340..10477)
                     /locus_tag="ACGXWR_002456"
                     /inference="COORDINATES: protein motif:HMM:NF018513.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
     gene            complement(10521..>11381)
                     /locus_tag="ACGXWR_002457"
     CDS             complement(10521..>11381)
                     /locus_tag="ACGXWR_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HFK0803969.1"
                     /translation="EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPD
                     KYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKR
                     YKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIIS
                     YSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMS
                     RKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLS
                     PVEYRKQSIK"
BASE COUNT         3351 a         2365 c         2125 g         3540 t
ORIGIN      
        1 aatacctaat gacatcaaga tcggcaacac aataactgca atagaaatca ctggtccgat
       61 tcctgtcatc gacatgaata taacagcggt tacaatacat agtaagctca tcgtgattct
      121 tggcttgtcc cctccaagtt caactacctt tcgaatcagg gtagctgcga ttccgctatc
      181 tactagaaca cgcccgaaaa aggcaccaaa gaagacattt accaagatcg atttggcgta
      241 ctcagctggc cccgtcgtat agatatgcgt caacacatca attactcctt gcccttccat
      301 cgccgagttt ggtgaaaacg tgtttccgac tagcgctaat cccatccata cagtagccat
      361 gatgacaaaa gccgaccatc aagttgtagc cttttacaca gtaccagacc atgaaaaaga
      421 atgagataac taacaaaata ccaataataa tatcactcat gttattcctc cgtccatttt
      481 gtttttctga taagcaaact aatatatcag tcaaactcat tctaacttat gtagttagcg
      541 ctttcattaa aggatgacca taaatgttca gttttcaatt aaaaaacctt aattatgtta
      601 ttttagactt atacgttatt gtcctgtttc atttgatgga ggattgtaaa taaaaaaaga
      661 ggaaagaaca taacttttcg ttatcttctt tcctctttat aattgtttag cttatttagc
      721 caaagcttct tttgcttggt cagccaatgc agtaaatgct gctgcatcgt taacagccaa
      781 gtcagctaac attttacggt tgatgtcgat ttcagcaact ttcaaaccgt gcattaattt
      841 tgagtagctc aagccattca tacgagctgc tgcgttgata cgagcaatcc acaatttacg
      901 gaagtcgcgt ttcttttgac gacgatcgcg atatgcgtag ttgtatgaat tcattacttg
      961 ttcttttgct gttttaaata aagtgtgttt tgaaccgtag taaccttttg ctaattttag
     1021 cactctttta cgacgtttac gagttactgt tccaccttta acacgtgcca tgtataattc
     1081 ctcctaataa aaataaatct tcagattctg ttatttgtac ttcttatttc atttttgcta
     1141 gttgttggcg aatacgtttg aagtcgccac tagaaaccat gcttgcttta cgcaattgac
     1201 ggcgttgttt ttttgttttg ccgtggaaac ggtgacttgt aaacgcgcgg aagcgtttca
     1261 atccgccttt accagtacgt ttgaaacgtt ttgctgatcc gcggtgtgtt ttttgttttg
     1321 gcatgactat atttcctcct caaaatcttt cgttatccga ctatcggctg tccaacagcc
     1381 agttagtcat tcaaattact tactgtcgtt tttcggtgcc agcgtcaaga acatgctgcg
     1441 tccgtccatt ttcgcttttt gttccactgt tgcaatatcc gcagtttctt cagctaagcg
     1501 attcaagact ttttgaccaa tttctttatg ggtaatggca cggcctttga aacggataga
     1561 agctttcact ttatcgccct tttccaagaa cttacgtgca ttacgaagtt ttgtattgaa
     1621 gtcattcaag tcgatcgtag gacttaagcg aacttctttt acattgatca ctttttgttt
     1681 tttacgcgct tcgcggtctt tcttttgttg ttcgaaacgg tatttaccgt agtccatgat
     1741 tcgcgcaact ggtggtttcg caccaggggc aactaacaca agatccaagt ttgcttgttc
     1801 tgcaatattc aatgcttctg cttttgtctt aactcctaat tgctcaccat ctgaaccgat
     1861 caatcgtaac tctcgtgcac gaatgccgtc gttaaccatc atatcctttg ctatggtcat
     1921 tcacctccaa atattatgag agaaagaaaa gcttaccgaa taaacggcaa taaaaaaacg
     1981 agttctctta cagaacccgc gcgtacttca cctaatagaa ccagtgaaaa ctatctagcc
     2041 cagtgacatt atcaactaag gcgagaagcg ggtgcttctg cttttatttc tcaaccatta
     2101 tagtatagca aaaactaatc tttttgtcaa tgtttttcat acagtttgtc ttccttttct
     2161 gaaaatgatt agattagcag gctttctagc agtgattccc gcttctttgc tatactaaag
     2221 aaaaacgagg tgaacccaca tgaaaaaaat cgaacctatt ccaccttctc ttcctcttct
     2281 tacaaaggga gagttttatt tagaagatga ggagatcttc tctggtcttc tgatcaacgg
     2341 aggtaaccaa agctatctcg atgccaaaaa tatggtatta agagagagtc atatccaaaa
     2401 acttacgatg caaaaaacag gtttacgtca ttttgaatgc agtaatgtca tttttgaaaa
     2461 atgtgatttt tccaatctgg agtggattgg tggcagtttc caccaagtcg tgtttcatca
     2521 atgtaaatta acaggtacga attttgccga aagttatctt cgagactgta ctttcactga
     2581 ttgtattgct tcgatggctt cctttagtag tacaaacttg aaagctgtct ccttcgatca
     2641 ttgtcaatta gaagacagcg aattttatga ggtcacttgg aaaaaccttt ttttgtctga
     2701 caatcagtta accggttcga actggtttcg aacttctctg aagggattag actttacgac
     2761 taatttcttc acaacaatcg ctttatctca agattctttg gcgggactaa tcgtcaatca
     2821 agagcaagca cttgtgatcg cccaagccct tggtttgcag atcaaagact agatcaacga
     2881 atccgccgcc acagtgcaat aagcatccaa atagataaga ccaaactgat gatcaaggcg
     2941 atttcccatc cgaaaacgga atgggtaaag ggtaactgga gattcattcc gaagaatcct
     3001 gtcacaatag ttggaacggt caagatcagc gaccagaccg tcaaaaattt catcgtgtca
     3061 ttcaagttgt tattcagcaa attattataa gtgccagaga gctggtctaa aatctgcgaa
     3121 gctaagttcg tcatttcaac tgcttgtcgt gcttcgatca gtgcatcgtc caactcttct
     3181 ttttcctttt ctgacaactt gcgataaata gccagtgcct tgatttgttc taaaagtact
     3241 acattttgtt ttgttcctgt aactaagtaa accaaaccga tctctaaatc tgaaagttgc
     3301 agcagattct tgttcgttgt tttttctctt aatttcagat taagccgctg acgttcacta
     3361 ttcacttcct cgattaaagg aaaaaaggaa tcagaaatca aaaacaatgt acgaaacaat
     3421 aaactgtata cactcatgtc tggcatccgt tccaaaagcg atcgaattag tcgaatcacg
     3481 tactcggtat tcggcgtggt aaatgtaaac aaaccgtctt cttttaaaat aaaagcgata
     3541 ggactagttt cataatgatt atcgactttt tgctggtgcg gaacatttga tacaagcagt
     3601 aacgcttcat caaaagaatc gtactctacg cgcgcccgtt catttttatc tagagaataa
     3661 gtcagcatct cgtcactaat gccatattct tcttttaagt ttttaacagc tagcacatcg
     3721 ttttgctgta cattgatcca aaaattacgg tcttgattaa aatagtgttt ttcccgcata
     3781 ctctatcctc ctgacatttg tttccagtat aaagaaaaaa gtcgctcaaa taaaggttta
     3841 ccctttattt gagcaactgt aaatcaaatg gatactttgg tttggcgaat ctctgctaat
     3901 ttttcttcga tcattttcaa gacttcttct tttgcttgag gatcttccac aaaattatag
     3961 cggtctccat cgatttggat ttttggactt tctttgtatt cttcatacca ttgatcataa
     4021 cgtctgttca attctttgta ataatcgtat agacttgggt caaaggacaa ttgttcatac
     4081 gaacgaccac gtttttcgat acgctctaac atcgtatcaa aagatacacg aatatgaact
     4141 aataaatccg gatgtttttt atgggcagca tagggaagtt cttccatcat gttttccagc
     4201 agttcatcat acacacaaac ttctgtttct gttgctcttc ctagatctgc atttagatgg
     4261 aaaagcagtg aatcttcata aatcgaacgg tccaatacat tattgtcatc tttcattgct
     4321 tgtttgatgc ttgcaaaacg tttattcaaa aaataaattt gcagcaaaaa agcatactgt
     4381 tcagggtttg cataaaataa gggcaagact tcattatcat caatcgattc ataaaatgcc
     4441 tgactatcaa agtgttcagc catcatttct gttaaacttg attttccggc accaattgta
     4501 cctgctaaaa cgatcacgct catttacctc cagctcactt catcactaaa tattgtgttt
     4561 aactccaacc ttttttaaat atacccccaa tatctagtag tgtcaattgt attttttcta
     4621 gtcaaagaag aaaaaaagtc aaaaaattct taagaaaaaa gtgttttttc tttagaaaac
     4681 gtattcttag ttttacttct gagatggttt tagtaaaata aaggaggaat gttttttgag
     4741 acccttagtg gacaaaaaaa ttcgtgaagc agcgcaactc gttttgggcg ctttattttt
     4801 tgcttaaaaa tcacttttac gtgagaagga gttagattat ggcaaactat ggccaaggag
     4861 aatcaagcgg aaagatcata ttgatgggcg agcacgcggt tgtttatgga gaaccagcga
     4921 ttgcctttcc tttctatgca acaaaagtca ccgcattcct tgaagagctg gatgcaatgg
     4981 acgatcaact ggtttcttcc tactattcag gaaatttagc cgaagctcct catgcattaa
     5041 aaaatatcaa aaaattattc attcacttaa aaaaacagca tgacatccaa aaaaacttgc
     5101 aactgaccat tgaaagcacg attcctgctg aacgtggaat gggatcaagc gctgcagtcg
     5161 ccacagcagt cactcgtgct ttttatgatt acttagcatt tcctttgtct cgtgaaatac
     5221 tattagaaaa tgtccagctt tcggaaaaaa tcgcccacgg taatcctagt ggaatcgatg
     5281 cagccgctac tagcagcttg cagccgattt attttacaaa agggcatcct tttgactact
     5341 tttctttgaa catcgatgct tttttgattg tcgctgatac aggaatcaaa ggacaaacaa
     5401 gagaagccgt caaagatgtc gctcacctct ttgaaaccca gcctcatgaa actggacaaa
     5461 tgatccaaaa attaggatac ttgacgaagc aagcaaaaca agcaatcatt gagaattcac
     5521 cagaaacgtt ggcacagaca atggatgaat cacagtcact tctggaaaag ctgacaatca
     5581 gcaatgattt tcttaatcta ttgatccaaa cagcaaaaga taccggggca ttgggtgcca
     5641 aattaactgg cggtggacgc ggtggctgta tgattgcatt agcacaaaca aaaacaaaag
     5701 cccaagaaat cagtcaagca cttgaagatg cgggtgctgc tgaaacttgg atacaaggat
     5761 taggagtaca tacctatgtt taaaggcaaa gcacgcgcat ataccaacat tgctctaatc
     5821 aaatattggg gtaagaaaaa tgaagaactc atccttccaa tgaacaacag cctttcgtta
     5881 acattggatg cattttatac agagacagaa gtcatctttt ctgatagcta tatggtagat
     5941 gaattttatc tagatggcac cttacaagac gaaaaagcaa caaaaaaagt cagtcagttt
     6001 cttgaccttt ttcgtaaaga agccggcctc tcactaaaag cttcagtaat cagtcagaat
     6061 ttcgttccta ccgcagctgg attagcctcc tctgccagcg ggctagctgc tttagcagga
     6121 gcttgcaata ctgctcttaa gcttggatta gacgatctct ctctttcaag atttgctcga
     6181 cgcgggtctg gttcagcttg ccgaagtatt ttcggtggtt tcgttgaatg ggaaaaaggc
     6241 catgacgact taagttctta cgctaagcca gtcccttccg attctttcga agacgattta
     6301 gcaatggttt tcgttttgat caacgaccag aaaaaagaag tgtccagcag aaatgggatg
     6361 cgtcgaacag tcgaaacatc cagtttttat caaggctggt tagattccgt tgaaggggat
     6421 ctatatcaat tgaaacaagc aatcaaaaca aaagatttcc aacttctcgg agaaacgatg
     6481 gaaagaaacg gactaaaaat gcatggaacg actttagctg cccagcctcc attcacttac
     6541 tggtctcctg acagcttaaa agcgatggat gcggtgcggc aattgagaaa aaaaggcatt
     6601 ccatgctact ttacgatgga tgctggccct aatgtcaaag ttttagtgga aaacagccat
     6661 ttatctgagg tacaagaaac atttaccaaa ttatttagca aagaacaagt aattactgcc
     6721 catgctggtc caggaattgc gattattgaa taaagggaga tttttatgat tgaagtatct
     6781 gcaccaggca aactctatat tgccggagaa tatgcagttg ttgaaacagg acatccagca
     6841 gttatcgctg cagtcgatca attcgtaaca gtcactgtag aatccgcacg aaaagtcgga
     6901 agtatccaat ctgcacaata tagtgggatg cctgtacgtt ggacaagacg caacggagaa
     6961 ttagttttag atattcggga aaatcctttt cattatatcc ttgctgctat tcgtttgact
     7021 gaaaagtatg cacaagaaaa aaacattctt ttatcctttt atgatctgaa agtaacaagt
     7081 gagttagaca gttcaaatgg ccggaaatat ggattgggtt ctagcggtgc cgtgaccgtt
     7141 gcaacggtca aagccttgaa tgttttttac gcgttgaatt tatctcaatt ggagattttc
     7201 aagattgcag cactagccaa tttagcagtt caagataatg gttcctgcgg cgacatcgct
     7261 gctagctgtt atggtggctg gatcgctttc tcaaccttcg accatccttg gctccaagaa
     7321 caagaaactc agcattctat cagtgagtta cttgccctgg attggccagg tctatccatt
     7381 gagccattga ttgctcctga agatttacgt ttattgattg gttggacggg tagccctgcc
     7441 tctacttctg atttggtcga tcaagttcac cgttcgagag aagacaaaat ggtggcttat
     7501 cagcttttct taaaaaacag tacagaatgt gtcaacgaaa tgatcaaagg gtttaaagaa
     7561 aataatgtaa cgttgatcca acagatgatt cgaaaaaacc gacaattact gcatgattta
     7621 tctgcaatca ctggggtcgt catcgaaacg cctgctttga acaaattgtg taatttagct
     7681 gaacagtatg aaggagccgc aaaatcttct ggtgcaggtg gtggcgattg cggaatcgta
     7741 attgttgacc agaaatctgg catccttcct ttaatgagtg catgggaaaa agcagaaatc
     7801 actccactgc cgttacatgt ctatagcgat caaagaaagg aaaaccgatg aatcgaaaag
     7861 acgaacatgt ttcactagct aaagcctttc atgataaaca aaaaaacgaa tttgacttcg
     7921 tacggatcat ccataaccct ttgccgcaaa tagcagtttc tgatgtcgat ctaagtacac
     7981 aggcagttgg gtttacacta agcagcccat tttatatcaa tgcgatgact ggcggaagcg
     8041 aaaaaacaaa aaaaatcaac caagatcttg caatcgtcgc aagagaagca gatttgatga
     8101 ttgccactgg ttcagtcagc gctgccttga aagacccttc tttagccgat acttatacga
     8161 ttatgcgaca agaatatcct cacgggaaaa tcattgccaa catcggtgca gggacttctg
     8221 tcgaaagagc ccaagaagct atccgattgt ttcacgcaga tgccttacag attcatttga
     8281 atgcacctca agagttggtt atgcctgagg gagaccgtga ttttaccaat tggaaagtac
     8341 ttattcaaga gactcaaaca gccattgacg tccccctcat cgtaaaagaa gtcggttttg
     8401 gcatgacaag agaaacgctc aatgatctag ctgctttagg agttcataca gttgatatca
     8461 gcggtcgaag cggaacaagc ttcacccaga tcgaaaacgc ccgtcgctcc aagcgggaac
     8521 tgagttattt agctgactgg gggcaatcga cagtctcttc attgcttgaa gcaaatgaag
     8581 cagacacttc tatggaaatc ctagcctccg gaggtatccg caatgcctat gacatattta
     8641 aagccctttg tctcggcgca aatgcagtgg gtacttcagg aaccgtactg acgcatctga
     8701 tgaatcacgg cgtagaagaa actattatac tgatgaagca atggcaagaa gagcttcgtc
     8761 tgctttatac tatggtcggc gcaacgaata ccgcggccct acaccaacaa tcactgatct
     8821 tttccggacc agtgaaggat tggtgcgaag caagagggat cgacttagtg aagtatggaa
     8881 gacgcacaga aaagagcgtg ggacaaaagt aaagaacact tttatcccac gctctaaaca
     8941 cgtataaacg gcggaagcaa aagcaactcc ttcggaaata agctgaaatt cacaaaaatt
     9001 tgaaaagcaa ttttcgtgaa ttccttctta tttcttggag ttaaacgctt ctgtcccagc
     9061 ctcttttttc gaataaatga tgtttaatca gctgtccttc ggtattcgtt caagccgctg
     9121 atttcacaac ctctccacta aacggtgtac taaagctctt ttaaggttgt tttccgatat
     9181 aggcaagtat gcctccgtcc acatacaaga catggccgtt aacgaaatca gatgcgctag
     9241 aagccaagaa gacagatggt ccagccaaat cgattggctc gccccagcgt gctgctggcg
     9301 tacgtccaac gataaattga tcgaatggat gacgttcacc gttttcttgt gtttcgcgta
     9361 atggagcagt ttgcggtgta gcaatataac ctggtccaat tccattacat tggatattgt
     9421 attgaccgta ttcagaagcg atgtttttcg tcagcatttt taatccgcct tttgccgcag
     9481 cataagcact gaccgtttcg cgtcctaatt cactcatcat ggagcagata ttgatgattt
     9541 taccgccgcc tttttcgatc atatcccgaa taactgcttt tgaaacgatg aatggggcat
     9601 ttaaatccac gtcgattact tggcggaagt ctgccgcatc catttcgatc atcggtgtcc
     9661 gtttgatgat ccctgcattg ttgactagaa tatcaactga acctacatct tctttgatct
     9721 gttgaaccat cgcttgaacc gcttcttcat cggtcacatc gcagacataa ccttttgcat
     9781 cgatgcctgc ttctttataa tgcgctatac cttcatcaac tgattcttga ttcaagttat
     9841 taaatacgat ttttgctcct gctgtagcta aagagcgtgc aatctcaaat ccaataccat
     9901 agacagcacc ggtgactaat gctacttttc catctaaacg aaacatatcc atactaaatt
     9961 ccatcatttt ctctccctta tgcttatttt aattgatcca tttgcaccat atccatgtct
    10021 gtataggtga tattttctcc gcacattgcc cagatgaatg agtaattgct tgtacctaca
    10081 cctgaatgga tcgaccagct tggcgaaata atggcttgtt cattgtctac gactaaatgt
    10141 tttgtttcat ctggtttgcc catcatatgg aacacacgtg tatcttcatt ggcataatca
    10201 aaatagacat aagcttccat acgacgttca tgtgtatgac aaggcatcgt attccaagca
    10261 cttcctggtt ctaaaatcgt ataacccatt tataaatgac agctatcgct gaagcttcta
    10321 ctgctgtaaa tatccccgtc aagataccac cgataatgat gacaatcaat agaaggctag
    10381 gaatcgcctc ttttattatt tttccagcat gagccatctg tcctttttcg acaacagggt
    10441 atttattctt tttagcaacg atgaatgcta ctagcatgat tcctagcgcc cacaaagtga
    10501 actgaacccc aaaagttgaa ctatttaatg gactgtttcc gatattctac tggagatagt
    10561 ccatttaact ttagttttat ccttttgtta ttataccacc taatatactc atttaattta
    10621 ctttgaaata tctcaattga tcggaatttt tctcgataaa aaaactctga tttaagcaca
    10681 ccaaaaaaat tttctattac agaattatct aagcaatttc cttttctaga catgctttga
    10741 ataatgttat tctcttttaa ttttttttga tattgtggca tctgatactg ccatccttga
    10801 tctgaatgta gaatcagtga accctcagtt cccttttttt taattgcttg ttgaagcatt
    10861 tcttcaatca gtttatatgt tggactagtt gatatactat aactaattat ttctccgtta
    10921 aataaatcaa gtataggaga tagatagatt tttcttcctt ttatcttgaa ttcagtgacg
    10981 tctgtcaccc attttttatt gggtgtatct actgaaaaat ttcgttttaa cacattcttg
    11041 gcaatttttc ctactgttcc tttataagat ttatatcgct ttattcggat ttgacaggta
    11101 agtcccattt gggacattaa ttttctaact gttttatgat tgattgtata tcctttcatc
    11161 tttaacgcta aagtgactct acgataacca taagagtttc ttgattcttt tacaatcgct
    11221 gtaatttctt gctttatctt gctatattta tctggcttat ctaatttttt tacccagtaa
    11281 taataagttg acttcgctaa ttgtgcaatt gaaagtaata gattcaattt aaattctttt
    11341 ttgagctgaa ggattgtttt aaccttgatt tcttcttgct c
//
LOCUS       DAYNVV010000078        11253 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.081, whole genome shotgun sequence.
ACCESSION   DAYNVV010000078 DAYNVV010000000
VERSION     DAYNVV010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.081"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="ACGXWR_002458"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="ACGXWR_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFK0803970.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="ACGXWR_002459"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="ACGXWR_002459"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HFK0803971.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="ACGXWR_002460"
     CDS             complement(2169..2906)
                     /locus_tag="ACGXWR_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFK0803972.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="ACGXWR_002461"
     CDS             complement(2997..3524)
                     /locus_tag="ACGXWR_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803973.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="ACGXWR_002462"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="ACGXWR_002462"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HFK0803974.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="ACGXWR_002463"
     CDS             complement(4401..4886)
                     /locus_tag="ACGXWR_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HFK0803975.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="ACGXWR_002464"
     CDS             complement(5039..5236)
                     /locus_tag="ACGXWR_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803976.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="ACGXWR_002465"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="ACGXWR_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HFK0803977.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="ACGXWR_002466"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="ACGXWR_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HFK0803978.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="ACGXWR_002467"
     CDS             9211..9423
                     /locus_tag="ACGXWR_002467"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit epsilon"
                     /protein_id="HFK0803979.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="ACGXWR_002468"
     CDS             9425..11104
                     /locus_tag="ACGXWR_002468"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFK0803980.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
BASE COUNT         3265 a         2429 c         1971 g         3588 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaa
//
LOCUS       DAYNVV010000079        10928 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.082, whole genome shotgun sequence.
ACCESSION   DAYNVV010000079 DAYNVV010000000
VERSION     DAYNVV010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10928
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.082"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..154
                     /locus_tag="ACGXWR_002469"
     CDS             <1..154
                     /locus_tag="ACGXWR_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HFK0803981.1"
                     /translation="SLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTL
                     RYSLGY"
     gene            complement(208..486)
                     /locus_tag="ACGXWR_002470"
     CDS             complement(208..486)
                     /locus_tag="ACGXWR_002470"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803982.1"
                     /translation="MENKVGYVRYNFFSSTPIMKDFASFNEALAVELSHDRERIHYEK
                     HVIINDLWNTEKTDLLALPDTDYPVFKEIEVKANKYNEIKQNKITNLS"
     gene            complement(601..1209)
                     /locus_tag="ACGXWR_002471"
     CDS             complement(601..1209)
                     /locus_tag="ACGXWR_002471"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0803983.1"
                     /translation="MTDINTIRNLRNNHDKSINHIAKELDVNWRTAKKYADDDLLPQP
                     KARKKTGMMYTEKWGGIVSLWLSEDAKLPNKKRRTAEAMTTALKADGFPGSYRTVCVF
                     IQDWKATHYLETLEDQGFERLEHPPAEAQLDFGTMEVCHDGAFKDVKVLVMTFPFSNA
                     GFAVVLPAENQECLLEGMKELFSQSGGVPRKIRIDNMSTAVT"
     gene            complement(1613..2437)
                     /locus_tag="ACGXWR_002472"
     CDS             complement(1613..2437)
                     /locus_tag="ACGXWR_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFK0803984.1"
                     /translation="MEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAGANKKLV
                     YNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLKILTTFL
                     YVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKFVYDDFS
                     DELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIGIPYINNL
                     GLPEQEVMKIGNKLNDSRVEKILTCHCTGSKAFNILKTQLGNKLEAIKTGQHLEIS"
     gene            2780..3196
                     /locus_tag="ACGXWR_002473"
     CDS             2780..3196
                     /locus_tag="ACGXWR_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFK0803985.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            3193..3663
                     /locus_tag="ACGXWR_002474"
     CDS             3193..3663
                     /locus_tag="ACGXWR_002474"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFK0803986.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            3677..4450
                     /locus_tag="ACGXWR_002475"
     CDS             3677..4450
                     /locus_tag="ACGXWR_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFK0803987.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAASPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            4464..5276
                     /locus_tag="ACGXWR_002476"
     CDS             4464..5276
                     /locus_tag="ACGXWR_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFK0803988.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            5330..6295
                     /locus_tag="ACGXWR_002477"
     CDS             5330..6295
                     /locus_tag="ACGXWR_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFK0803989.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            6432..9155
                     /locus_tag="ACGXWR_002478"
     CDS             6432..9155
                     /locus_tag="ACGXWR_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFK0803990.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESQILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGGSIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            9168..9800
                     /locus_tag="ACGXWR_002479"
     CDS             9168..9800
                     /locus_tag="ACGXWR_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFK0803991.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKALRKEVKPLLDFLKKRDIP
                     LALASSSPAVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTAALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            10008..10232
                     /locus_tag="ACGXWR_002480"
     CDS             10008..10232
                     /locus_tag="ACGXWR_002480"
                     /inference="COORDINATES: protein motif:HMM:NF015692.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HFK0803992.1"
                     /translation="MQQNQNTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEVI
                     PENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            10334..10567
                     /gene="relB"
                     /locus_tag="ACGXWR_002481"
     CDS             10334..10567
                     /gene="relB"
                     /locus_tag="ACGXWR_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HFK0803993.1"
                     /translation="MSQSTITFRIPDDEKELVLEYAKAHNSSLTELYRNAVLDKIEDE
                     IDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            10557..10826
                     /locus_tag="ACGXWR_002482"
     CDS             10557..10826
                     /locus_tag="ACGXWR_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFK0803994.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
BASE COUNT         3625 a         1741 c         2136 g         3426 t
ORIGIN      
        1 ttccttagaa aaattaggtt gtcaaaattt caactcacgt tctgttaaag ggctagagag
       61 tagatttgaa agcatattac tggcttacag tgttctatta agtcgagcac aacgacgttt
      121 tgaaggaact ttgagatatt ctttaggata ttaaaattaa ctagcaccac gggtaaaata
      181 aatagttttt ctatcaagta tattgaacta cgataaattt gttattttgt tttgtttaat
      241 ttcgttgtac ttattggctt tgacttcgat ttctttaaat actgggtaat cggtgtccgg
      301 caaagctagc aaatctgttt tttctgtgtt ccatagatca ttgataatga catgtttttc
      361 gtaatggatt cgctctcgat cgtgtgacag ctccaccgct aatgcctcgt tgaaactggc
      421 gaaatccttc ataatcggtg tagatgaaaa gaagttgtac cgtacatagc cgactttgtt
      481 ttccatacta cctttctcgt ttccgctacg tggattgcac acctgtgtct caaaaccata
      541 gtgcatagaa aatcggagga aaccgtcagt cagcaccgct tgttcagtct ttgtttttgt
      601 ctaagtaacg gccgttgaca tattatcaat ccgtattttc cgaggaacgc cacctgattg
      661 gctgaagagt tctttcatgc cttccaacaa acattcttga ttctcggcgg ggagtacaac
      721 ggcgaatcct gcattactaa aagggaaagt catcactaat accttcacat ctttaaacgc
      781 tccatcgtga caaacttcca tcgtaccaaa atcaagttgc gcttctgctg gcgggtgttc
      841 aagacgctca aagccttggt cttccagtgt ttccaagtag tgtgtcgctt tccaatcttg
      901 aatgaataca cagactgttc ggtaggatcc tggaaagcca tcggctttta aagcagtagt
      961 cattgcttca gcagtcctac gctttttatt tggcagctta gcatcttctg aaagccatag
     1021 ggaaacgatg cctccccact tttctgtata catcatacca gtctttttgc gtgctttagg
     1081 ttgcggcagc aaatcatcat ctgcatattt tttagccgtg cgccaattta catctagctc
     1141 ctttgcaata tgattaatgg atttatcatg attatttcgt aaatttctga tagtattaat
     1201 atcggtcatt gtgagcatac ctttcttacc tccagttaca gtgtcgagac tataacttta
     1261 gaggagtttc aggttgcccg caatggcttt ttatcttaac ttaatcgatt tgcggagttg
     1321 tgtagttttt cgttgcactt gtatgtactt ttattctgcc ataaacagct taatgaatgt
     1381 ccacttgaaa aagtgaataa acgaaataga tgactcgatt taataaggaa gtaaacccac
     1441 acagaaatat aggtgatttt ccttgaatga ccaagatatt gaaagttagt gaaaaaacac
     1501 aaaaaggtag ccctattcac agaaggtctg ccttttgtgt tatcgccagc aaacattaga
     1561 gggggtattt catatagctt ttgtcctctc gacagtccta tcagtttctc ttttaactta
     1621 tctctaagtg ctgtccagtt ttaatagctt ctagcttgtt tcctaactgt gtttttaata
     1681 tgttgaaggc ttttgaacct gtgcagtggc aagtaaggat tttttctact cgtgagtcat
     1741 tcaatttatt tccaattttc attacctctt gctcaggtag acctaaatta tttatataag
     1801 gtatgccaat catatggaag ccaccaatta ggtattttat gggtttagtc ggaaatgttt
     1861 caagagcaat ttccatcata tcgataatgc catgatgact acagccagta aagacaatca
     1921 gaccgtcttc ttgctcaatt acgaccaata attcatctga aaaatcatca taaacaaatt
     1981 tatcatccat ctttttgtat aaattcttgg tggtcgagtt tgctttgcct agggggatga
     2041 tatggaagct cggagcaagt tctgttttcg tttttattgt atgtaaattc tcatgcattt
     2101 taaggatttc atttttagga ataccaacat acagaaacgt ggttaaaatc tttaaataat
     2161 ggggtaaagt tacaccttca gctgtataaa taggggcgtt tcctgatttt aaatatctta
     2221 acccgccggt gtggtcagaa tgaccgtgtg aaataatcac tgcctccaga tcattcaaag
     2281 tttcccccat tttagtcgca ttatagacta attttttatt agcgccagca tcgaagagat
     2341 atttcttccc tgagtagtta attaagagag ataacccatg tccactttta aagttcaaat
     2401 ttattcttga gttttcaaat aaaaccttga tttccactat aacatctcct ttcacatgaa
     2461 cgtgtattca tatattgtag cacattaagt tctatttttt gttgtaatta ccgaaaaaaa
     2521 tattaatgga cgctttttac gctttatttc gtatgtggaa gaaaatttct taggatgtgg
     2581 cgggggattg gggcaaagct aaattccaat tacagtgatc atttaattag acacctttaa
     2641 atacccacac tttcatcaac actataattt agggaaagaa aagtgttggc atgatataga
     2701 aaaaccttta attaacagcg tttcctaaaa ttggcacgca tcttgcttat agaaaagcgt
     2761 aaggatagga ggaatgaaaa tggcaactat aattcttgcc agccatgggg aatttgctca
     2821 aggattaaag caaacagcga caatgattat tggagatagt gtaccaattc atgccttgtc
     2881 agcatttaga gatgaagatg aatctatttt ggtacaaata aaaaaacttt tagccacaat
     2941 agatatagaa gaaacctaca ttttaactga tattctaggt ggtagtgtga ataatgatat
     3001 gctcactatt attaaagagt atgagggatt gcaattaatt actggaatga acttaccttt
     3061 agttatttct attgcaacct ataatggaaa aattggggaa agtgagctag aaaagcttat
     3121 taaagagagt caacaatcag tgattgattg tagaaaatta ttagtagaac aacttactgg
     3181 aggagatgac ctatgattaa gttagtacgt attgaccatc gtttgttgca cggacaggta
     3241 gtattttctt ggagtaaatc attaaatatc aatcgtatta ttattgccaa taaagaggca
     3301 gcgaatgatg aattcaaaaa aatgtctttg aatttatcta aaccgactgg cattaaatta
     3361 acaatttttt cagttgaaca gttactagaa aaaatgccta aaatcgaaac acttaacgaa
     3421 aatatcatgc ttatttttgg taatacaaaa gaaattcgtc aattttgtga agcctatcct
     3481 aaagtacaag aaatcaacta tggagggata atcaaaaaag aaggttccaa gcaatttagt
     3541 aatgccattt tcttgaatga atctgagcaa gaagatgcca aaaaattaaa agctcttggc
     3601 attaaacaat ttattcaaca ggtaccaact tctaaaaaag aagatttgaa tacaatgtta
     3661 taaaggagga atgaaaatgc tcgttcagtc aattggttta gggttaatcg gtgttttttg
     3721 tattttagac tcaaggcttt taggaagaat gaattttgaa cgaccgttga ttgtcagtac
     3781 gcttgttggt ttggtacttg gagacatgga aaaaggatta attgttggag cctctttgga
     3841 attgatgtcc ttaggattag taaatatcgg agctgcttca ccacctgata tgaatatggc
     3901 atcaattatt gctacagcct ttgccatttt atcaaatgcg aatgcagaag cagcattaac
     3961 gattgccatt ccaatttcag tgttaggtca aatactaggt atcttaatgc ggacgatttt
     4021 gtcaaatttg actcacgttg cggatcgctt tatcgaacaa ggaaaattta gccaagcaag
     4081 gagaattcat atactttatg gctcgggatt atatgctctc atgtatttta ttcctatttt
     4141 tctagcaatt tattttggaa cgaatcttgt ttctcagatt gttgatgcga ttcctgagtg
     4201 gctaacaaat ggcttaacgg ttgcaagtaa aattttacca gcatatgggt ttgcgttgtt
     4261 attacaaacg atgttaacga aaaaaatggt gccattttta ttacttggat ttttaattac
     4321 tgcttattct ggattgggaa tcattggtat tgcagccttc gcatgtattg ttgcgtttgt
     4381 catggttcaa gttcaaggta aaaactcaaa tggtaaccaa aatgagccag atccattaga
     4441 tgacttataa ggaggtagat taagtgaaag agaaagatca aaatgcatgg aaatatcggc
     4501 agttcttatg gcgttcatgg gcaattcaag cctcatggaa ctatgaacga caaatgaaca
     4561 tgggttttat gtacggaatt gcaccaattc tagataacat ttacaagaat ccagaagatg
     4621 aagcaatgaa gaaagaagct tacgagcggc atatgatgta ctacaactgt acccctcaaa
     4681 caagtgcatt tgtgttaggg ttaactgctt ctatggagga gcaatactac gaagaccaag
     4741 aaaactttaa tccggaatca atcagtgcag tgaagacttc tctgatggga ccgctatctg
     4801 gtgttggtga ttctttcttt caaggaacga ttcgggtatt agcctttgga ctaggaatta
     4861 atttagccca acaaggtagt attttaggtc caattctagc aatgttaatt tcctttgtac
     4921 cttccttttt agttacttac tatggtggga aaattggcta taacatgggg aataaatact
     4981 tgtctaaact gtatcaagaa ggtttgatgg ataaagtaat gtatgtttgc tccattgtgg
     5041 ggttgatggt cattggttcg atgattgcca gcatgatcgg gattacaaca ccaattcaaa
     5101 tgggtaaagc ttttgtctta caagatgtat tagatagtat tatgccacaa tttttaccat
     5161 taggattaac cttcttcatg tactggttat tgcagaaaaa ggtcaaaaca ggatggatgt
     5221 tggcaatctg tttagtcgga ggaattattt ttagtttgtt aggtatctta caataaggga
     5281 ataaccaata aatttggttg aataatataa ataaggagga attcaattga tgaattcaaa
     5341 agaaattgtt aaagaaatcg tagcgaaaaa agaggtaaaa tcaatcgtat ttgttggctg
     5401 tggcgcttca aaagcggacc tttatcctgc aaagtatttt ctagaccaaa atgcgaagca
     5461 gttacggatt agtcattaca cagccagcga atttaactat gcaacaccag catctgtaga
     5521 tgagtcaact gtcgttattt cagcttcttt aggaggtacg actccagaaa cagttgaagc
     5581 taacgcagta gctaaagaaa aaggtgctac agttattagt ctaacacgaa gcattgactc
     5641 accgttaaca aaagatgcag attatgtaat ttatcatcga tttgcagaga actatgctgc
     5701 taaattagaa aaaacaggct actgtttaga attggcagta gaacttttac atcaagtaga
     5761 aggttatgac cattatgaag caatgcaaga aggatttgct actatctatg atcttgccca
     5821 aaaaagtgca gaatcagctc gtaaagatgc gaagaaattt gctgaacgct ttaaagatga
     5881 aaaagttatt tatgtaatga gtagtggtgc tacacatgaa gtagcatact caacatcaat
     5941 ttgcttgatg atggaaatgc aatggattaa ttctggtacc ttccattcag gagaattttt
     6001 ccacggacca ttcgaaattg tggataaaga cgtaccgttt atattattaa tgaatgatgg
     6061 aaaaactaga aatatagatg ctcgagcatt aactttcctt gaacgctttg atacgaaaac
     6121 agaagttgta gatgccttgg attatggctt gtcttcacat attgctaaag aagtcttaga
     6181 ctactttaac ccattcgtga ttactgcagt atttagagtt tatgcagaag aattgtcaga
     6241 agcaagagaa catccattaa ctaagagacg ttatatgtgg aaactaactt attaaaaaat
     6301 agatcaaact aaataaggtg gcttgagaaa ttaagccacc ttgttttctt caatgtgatt
     6361 ttatacatat ggtaaaataa ctagtacata tggtaaaata actagtacat attgtgaaag
     6421 caggtggcaa gatgcagcga ttaaatgact atctttatca actaacattg cttttgaaat
     6481 ctacgccttc agataattat tcagctcgca gtatttcgca agctctacag ttgaatagaa
     6541 gtacaatcag tagctactta aatgaaggtg ttcgtgaagg gcttttcata aaagtaaaaa
     6601 gttacccggt tttattttta catagaacag ctcttgaaga actacatatc acactgaata
     6661 actccgaaat agaatcaatt gaaagcttgt taacaatttc tcaaaaaccc gcattagatc
     6721 aagtaattgg ctctaaagga agtttgaaag aagcaattga tcaaattaaa acggcagtct
     6781 tatatcctgg aaaagggttg cctttattat tgatcggcgc tagtggatca gggaaaacct
     6841 ttctagcgaa taaaatatat gaatatgcag tagaagaaaa ggtcattcac acatcggcac
     6901 ctttcataga ttataattgt gcacaatatg tgagcaatcc agagttacta tcctctgctt
     6961 tatttggcta cacgaaagga gcatttaccg gagcaagcca ggagcatact ggtttgctag
     7021 aaaaagccga tggaggagta ttgtttttag atgaagtgca tcgcttatct gaagaagggc
     7081 aagagaaatt atttacattt atggatacgg gtgaattctc tcctatgggg gataatagta
     7141 ttcggaaaaa agccgatgtt cgattagtct ttgcaacaac agaaaatata tatacgactt
     7201 tcttaccaac ttttcttagg agattgccag ttattgttaa tctacctaga tttcaacaac
     7261 gtccgtcgtt tgaacgtctg tcattgattg atgaattttt tgtttctgag agccaaattt
     7321 tagctaagga actatctgtt tctgatgcat tgattcattt cttaatgaat agtgattttg
     7381 aaggtaacgt ggggaatatt aaaaatatta tcaagtatgc ttgcggaaac gcatatatcc
     7441 accagaagag tcagcaaaca attcaagtta aattattgga tatgccttta gagtacagtt
     7501 ataaattcaa ggagcaacta aataaaccca gaaagaaaag agcagatcga atctactatc
     7561 cagaagaaac acgacaagtg caactagaaa gaaacaatca gctttttgtt caattttttg
     7621 accaattact tactggattc tctgaagtga ttgaaaataa caaggatatt aaactatttt
     7681 tagaagaaat ggttaccaag gtaacacaag taatggatac gcttattttt caagaggatt
     7741 acgaaaaaga gcagtcttta tacgccattc taaactatca tattcgtcaa agtattgatt
     7801 ttatgcgaga aagctacggg tttgaacaag atggtaaccg ggtagtcgct ttggccaact
     7861 atctatatgt caaggataat caagtgattt ttgaaaatag tcttcaagaa aagaaaacca
     7921 aagatcagct taacgaattt tttgctaatg ttcttgaaac cccttattgg tatgcaaaaa
     7981 aaatcttaag ccttttatct gagtgtttag atcaacctgt gtatgaagag gacattttct
     8041 ttattacgct atatttttat agtttgaatg tcacgaatgt taaaacaggt attaagagta
     8101 ttgtgctagc tcatggttat tctacagcta gtagtatggc gaatgttgcc aaccgtatgc
     8161 tgaataagaa cgtttttcaa gcttatgata tgcctttaga tattacatta gagaaaattg
     8221 aagcaaaatt gattcaattc cttggagatt atcgaacaga ttcaggcttg attttattgg
     8281 tagatatggg ttcactaaac caactaggcg gtttattagt gaatcatcta aatggaccac
     8341 tgttaatcat tgatcatatc aatacaccgt tattattgga agtcggccaa caagtattaa
     8401 acaataaaag tatcaccgaa ataggagcag aaattgaaac aagtcttact ttcaaaaagc
     8461 agttactact tcccaagaaa aagaaaaaga aagccatcat tacttgttgt tatacaggga
     8521 ttggtagtgc gacccagatt caggagattt taacgaaatg cttgaaagat gcagttagag
     8581 aattagtaat tattccgtat gattacaaaa agctgttaga aaacaagaat tttgagactc
     8641 cttttcaatt atacgatgtc atcatgattg taggtacaga agatcccaaa attaatcaga
     8701 ttccatatat tggattagat cgcctgatta atgggggaag cattggcgaa tttgttcatt
     8761 acttggaaaa agagctgact attgaagtga acgatttaca aaaagaatta attttcaatt
     8821 tttcaattag taaaattgtc gaaaatttaa ccattttgga tccagataag gtgctatctt
     8881 ttgtacaaaa agcaattaaa gaattatcga agttattaaa ttttgatttt tctaataatc
     8941 agctgttttt gttgtacctt cactgtagtt gtatgattga acgaattgta cgtaaagaaa
     9001 gtgtggatga gcaagaggac attgaagaat atatgcaagc aaatggagaa ataatggata
     9061 aaattcatag cgcttttttt gagattgaaa gggaatacac aattgaaata ccagatttag
     9121 agttgcgatt attgagcgat attgttcaag gataggagtg aattcgaatg acaatgggag
     9181 taatttttga tatggatggg gtactcatag atagcgagac attttatttt gagagaagaa
     9241 tgaacttctt tcaagaactg gagatagatc caggatcaaa ccagattgat gattatgtgg
     9301 ggaaaacaga agctgcaata tgggaaacat tagttcctga ggacaaatca ttaagagagg
     9361 aactttatcc gaaatatgta gattatcgaa aaacgcatcc aattgatttc gctaaagctt
     9421 tacgaaaaga agtgaaaccg ttacttgact tcctcaagaa gcgggatata ccattggcac
     9481 tggcatcttc ttctccagct gtcgagatag agagtatgct cattcaatgt gaacttactg
     9541 aatatttttc ctttgttata agtggtgagt cattaaaaca aagcaaacca catcccgaaa
     9601 tatatttaaa agcgaaacag caattagact gtgacttctt tattgcagta gaggattcaa
     9661 cgattggtat taaatcagca aaggcagcaa atatctatac ggcggcacta aaacaaccaa
     9721 tgcaaatcga tcagagtgaa gcagacatac aaattgaaag tctacaagaa ctggaacaaa
     9781 ttgttttaga aaaaggttag tgaattaatg gaaataaggc tatatatctg tgctagctat
     9841 tttgactaac caaaaaaact tgctataatt caggtgtagt aaaaggtgct ggtaacacct
     9901 tttacgaaaa tgcttcggca gtgataatgg gattggcttt ttaagttttt tattttgttc
     9961 gcaatcccta aggtcatgtg aatgatccta gggattgcta gaatattttg caacagaacc
    10021 aaaatacgaa tagttatcaa gcagccatat tgactgcggt caatttagga ggggatactg
    10081 atactactgc tgccgtaact ggtgctcttg cgggtattct ttacgggggt gaagtgatcc
    10141 ctgaaaattg gagaaaatcg cttcaaaatg accagcttct taaaacgatc agtcagagat
    10201 tttgcgatac cgtgctatct caaagaattt gaataatgga tatgatgcaa atcttgtttg
    10261 tactaacgtt gtattgacaa aaaggatttt atttagtaca atgttagtac aaatgatgaa
    10321 cggaggtaga atcatgtctc aatcaaccat tacatttagg attcccgacg atgaaaaaga
    10381 actggtatta gaatatgcaa aagcacacaa ttcttcattg accgaacttt atcgaaatgc
    10441 tgtactggat aaaatcgaag atgaaatcga tctacggact ttacggagtg caattgaagt
    10501 ttccaaagag aaaaaagaga gtggtatttc tcaagaggaa atggagaaac tgctaaatga
    10561 attataaagt catctacatg ccgcaagccc agaagcaatt aaaaaaaatg gacagaaacc
    10621 aagctaaaat aattgtcgcc tggatcagaa agaatttaga aaacacgact gacccgcgtc
    10681 agcacggaaa aggtttgact ggaaataaga gtggggaatg gcgctatcga attggaaact
    10741 atcgaatatt ggctaatatt tgtgattctg aaattgaaat ccagatattc tcaattggac
    10801 atagaagtac aatatataaa agataaccgt ttttggaacg aagtagagtt tcgaaagtca
    10861 atgtataatc ttttgaattt tgcataatac cacaggtaga aactacccga tactatcggt
    10921 tggtttct
//
LOCUS       DAYNVV010000080        10809 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.083, whole genome shotgun sequence.
ACCESSION   DAYNVV010000080 DAYNVV010000000
VERSION     DAYNVV010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.083"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(64..1173)
                     /gene="rpoD"
                     /locus_tag="ACGXWR_002483"
     CDS             complement(64..1173)
                     /gene="rpoD"
                     /locus_tag="ACGXWR_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HFK0803995.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(1197..3038)
                     /gene="dnaG"
                     /locus_tag="ACGXWR_002484"
     CDS             complement(1197..3038)
                     /gene="dnaG"
                     /locus_tag="ACGXWR_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HFK0803996.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(3220..5535)
                     /locus_tag="ACGXWR_002485"
     CDS             complement(3220..5535)
                     /locus_tag="ACGXWR_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFK0803997.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(5720..6580)
                     /locus_tag="ACGXWR_002486"
     CDS             complement(5720..6580)
                     /locus_tag="ACGXWR_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HFK0803998.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(6639..7271)
                     /locus_tag="ACGXWR_002487"
     CDS             complement(6639..7271)
                     /locus_tag="ACGXWR_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HFK0803999.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMRSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            7438..8199
                     /locus_tag="ACGXWR_002488"
     CDS             7438..8199
                     /locus_tag="ACGXWR_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFK0804000.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            8225..>10809
                     /gene="mprF"
                     /locus_tag="ACGXWR_002489"
     CDS             8225..>10809
                     /gene="mprF"
                     /locus_tag="ACGXWR_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFK0804001.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLVSVLPMIGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDP
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRR"
BASE COUNT         3062 a         2273 c         1911 g         3563 t
ORIGIN      
        1 tttttttctt ttaaaataaa ccaaacagtt ttactgattt ctcttctggt caatagtcca
       61 cgcttattct aagaaatctt ttaattgttt tgaacgagaa ggatggcgca attttcttaa
      121 tgctttagcc tcgatctgac gaatacgttc ccgagtaaca ccaaacactt tccctacttc
      181 ttccaatgtt ctcgtccggc catcatctaa accaaaacgt aagcgaagga cattctcttc
      241 ccgatcagtc aatgtatcta gtacatcttc caattgttct tttagtaact cataagctgc
      301 gtgttctgct ggacttgttg cttcctggtc ttctatgaaa tcacctaagt gagagtcatc
      361 ttcttcaccg attggcgttt caagggaaac aggttcttgc gcgattttca agatttctcg
      421 gactttttct gttggaagat ccatttccgc accgatttct tctggcgtag gttctcttcc
      481 aaggtcttgc agcaattgac gttggatacg tatcaattta ttaattgttt caaccatatg
      541 aactggaata cggatcgtac gtgcttggtc agcgattgct cgagtgatgg cttgacgaat
      601 ccaccatgta gcataggttg aaaacttaaa tcctttgcgg tagtcaaatt tttcaactgc
      661 cttcatcagt cccatgtttc cttcttggat caagtcaagg aactgcatgc ctcgtcctac
      721 ataacgttta gcgatactta ctactaaacg aaggtttgct tctgccagac gctgtttcgc
      781 ttcttggtcg ccttcttcga ttttcaatgc taacgctact tcttcttccg cagttaaaag
      841 ggagacacgg ccaatttctt tcagatacat acgaaccggg tcattgattt ttacaccggt
      901 tggcgcagaa agatcttctg tttttgcttg ttcagctttt ttctcagcac tcttcaagct
      961 gtgaattgat ggatcaccat tttcatccac cacactgata cctgcgtctt caatcttttg
     1021 gatcaatttg tccatttcat ctgcattcaa agtgaatggt gtagcaagct gattggataa
     1081 atcatcatat acaacttgtc gtttgggttt gttttctttg atgaaagctg ctactgctgc
     1141 ttcatacgtt tttttatctg ttccatttgc cataaaagaa ggcccccctt gagtagctat
     1201 ttggcttgtt ttaactgttt cgttaaattg atgatttcaa tcgtcaattc aagctcaagc
     1261 tgtttgtttc cagttcgtct ggcttcttgc tgcatttgtt tttttaatgt tatttcatca
     1321 gctaagccag atttgctgat cacatctagc aagtcttgga tttctcgtgg cgaactttct
     1381 tctgccaccg gtaaatattc gatttccacc accaaccgcc ttaaattttc atcttgcaaa
     1441 aagtctaaaa actctgcaag gttgaattca taatgttgtg agacatatgc atcgaataaa
     1501 aaataaactt ctgcatatgc atcatgaata aactgaaatt ctcgttcttt taaaatatta
     1561 cggacagaaa cttctttaaa tgcacgatat aatagaatct gctctgcctt ttctacttgc
     1621 gtcaaaggtc tctttttccg tgcagtttct tgtctcgtaa cctgagtgtg ttgactttcc
     1681 tgaggttctt gacgattttg ctgatttgtc cttcgaagat cgcgcagttg tttttgtatc
     1741 gtctctctgc cgatctgaaa ctctgttgac agttgagata gatacatatc ttgttcgatt
     1801 ggtgaaacaa ctcggctaag ttcaactagt aattcttcga ggtattcgat cttgtctttt
     1861 tcattatcta aatttttccc ttgttttaaa taacgtgatt taaaagtaaa gactgtttcg
     1921 cgcccatgag ccactaattc ttggaaagat gcttctccat acttacggag atattcatca
     1981 ggatcaagct tttctggaac gactacgaca gaaagtgcta atcgactgtt ttgccgaagc
     2041 aattcaatcc ctcgattggt tgcttcaaaa cctgcgttgt ctccgtcata gcaaaagacc
     2101 aattctttcg tcagcttttc catttgttgg atctgttgag ctgttagact tgtccccata
     2161 gaagctaatc cagttttgat accagcctgc catgcagcaa tcacatccat aaacccttcg
     2221 aacaacaaaa tttctccgtt tttccggata tcgcttcttg ctttatcaag attaaataaa
     2281 acttgtcttt tattgaacag ttctgtttct ggactattca agtatttggg ctgatctttt
     2341 tcctgccctt tttcaggtgc aagccagcgt cctgaaaaac cgatcgtctg gccttgagaa
     2401 ttacgaagtg gaaacatcac tctttgataa aaacgatcag acatacggcc atcatcatgc
     2461 gtgacaaaca atccagagcg ttctaacaat tcatttgaaa ttgattcatt cttgaatact
     2521 tgctgaagaa aagaacgctc attaggtgca aaacctatgt tgaattcttc aattaattct
     2581 aaagacaacc cacgactttg caaatattct aaagctggct gtccagcttt tgtatgcaat
     2641 agcatgtgat gatagatttc cgctgctttt tcatgagcag caatcagttt ccccgtagca
     2701 gattcaggat tttggacagc tatagtacgc tgacgccatt gatcttctaa cggtatctgt
     2761 tcgaagtctg ccacttttac cactgcttct ggaaaactta gaccttctag ttcttgaaga
     2821 aaagtaaaca cgtttccgcc tttaccacaa ccaaagcaat gaaaaatctg cttgtcttct
     2881 gcaacagaaa aagacggtgt acgttcttca tgaaaaggac acagccccaa gtaattttta
     2941 ccagactttt tcaactggac atattgtcca atcacctcaa cgatattcgt ttgactgcgt
     3001 actgtttcga taacctcttg aggaatccgt tgagccattt tttcaccccc tgctctattg
     3061 atatcttttg ggtttaacag aagatatttc aggagaataa ccggtaaaaa atcgcactaa
     3121 ctgaaatcag tgcgatttta aaggacacaa ttatacatgt ttgattgtat catatttcat
     3181 tgctttttca agtataacac atttctatct cattaagcat caatttgcta ctcttttcag
     3241 taactgattt tgaatatcag ccttccagta caatactcga agaacaatat ttacgagcat
     3301 gaatacaaag aagtatccta cgctctctcc caaccctaag tttacttcca aaattccatg
     3361 gaacagcatt gcagctacat atatccctac gatcgtcgtt actgctagga agatgcgcaa
     3421 tgggttgaag ggataacaag cttttacaac tgccatgcaa ctgatcccaa tcagcaagta
     3481 atacatcaaa gtagtagttt cagcatttcc ccatgcgaat gtttttccaa gtagatacac
     3541 cgcaatgata ttcactacta caagcaaggc atttggtaaa gcattaataa gtgctgtagg
     3601 caaataacgg taagtgattt ttcttttatc ttgttcaaaa gataaaaaga aggaaggata
     3661 cccttcaatc gctaaatcaa tcagcgtgat ttggataggg ataaacggaa atccaattgc
     3721 tgtaacggca catataatcg ataaaataaa tgaataaatc gttttgataa aaaagatgcc
     3781 tgagactttc gtcacattgt tgaccactcg gcgtccttca aacaggactt ctggcaatgt
     3841 agtaaaatca gagtccaaca ataccagatt cgcaatctga cgtgttgctc catcaccttc
     3901 tgccatagca atgctgcaat ctgcttctct taacgccaaa acatcattca caccgtcgcc
     3961 tgtcattgca accgttctgc cgctttcttt caattcattt accagcaatt tcttttgctg
     4021 cggactcact cgtccaaaaa ccgtatagcg atgagcagct tctcgcactt ccatttcttc
     4081 agtaatttga gaaagatcga catacgcatc ataattcggt aatcctgcac gtctagcgat
     4141 attggagaca gtaaaaggat tgtctccaga aatcactttc agatccacac cttcctcatg
     4201 aagataagct agtgtttctt gagcgttttt tcggattgga tcatcgattt caaacagagc
     4261 aaccggctca acaaatgctg gtttttcttc gttcaattgc tgatttggag cgatccccaa
     4321 cataagtacg cgatagccat tcgcttgggc tgtttttaga ctgtccggaa gccgatcttc
     4381 ttccaccaaa cgttcaggcg ctcctacgta cacgactccc agttctggaa attccatcgc
     4441 gccccatttg cgatcagaag aaaatgcgac tttgtttgtc acatcatacc gattagaaag
     4501 ctcaaaataa tctctcatag cccgcatagt gatgttgtta tcactgcttt ctgccagata
     4561 cgtccccata atttctggga tggctttctc gtacagcgga tgtagtgctt ctacccgctg
     4621 gatactcatt ttcccttcag taatggtccc tgttttatcc aagcataatg tatcgacatg
     4681 ggccagcgtt tcaattgaat acatgtcttg aacaaggatt cgtttttttg ccagtttggt
     4741 tacccctgtc gttaatgcaa tacttattag caataccaaa ccctttggaa gcatgcctaa
     4801 caaagctgct gcagatgcaa taacagaaat tttgatagaa gcatcgcgga tgaacagtgc
     4861 ttccaaaaat agtatgatcc ccaaaggaat aatcacgaaa ctagtgaatt tggatacttt
     4921 gcgaatcgaa tctacaagtt cagaacgaat agctttgtga gtctttgcct cgctagtcaa
     4981 gcggacagca taattatctg cacctactcg gataacttca gccatgacag aaccgcttgt
     5041 caaaaagctt ccagaaagca attcagctcc agtttctttg acaatcaaat cagattcgcc
     5101 tgtcaaaaga gcttcatttg cttctgcccg tccagatata acctgtaaat cggctggtat
     5161 ctgttctcct gctccgattt ttaccaaatc tcctaatacc agctctttag tagaaatcga
     5221 ttgttcttta ccgtcccgga tcactagtac ttctgattgg gaaacaatcg ataatttccg
     5281 tacaagattt cttgcatgta tttcttgata aattccaata acgatattga cgacaataat
     5341 tgctaaatac gccatgttgg aatacgcacc tacaaataac agacaaatcc caataccaaa
     5401 gttcagaaaa ttgaataacg tcaatatatt atcgctgaat atttgttttg tactttttga
     5461 tgcatcttcc tggtagtcat tttgctggcc agaagccatt ttctgaacta cctcttgctg
     5521 tgtaagtcca ttcattttct ttttctccat tttccgccaa ctttcaaaaa taatcacgtg
     5581 tttaagtcta gcgtgttcca agattaaaaa caacttgttt ttataaaatt tatagaaaaa
     5641 cacacgaatg attttacaaa aaagatgcca acctttttgt ttgaatcacc cgtgtgctgt
     5701 ttttattatc aatctatctt tacttatatt gttcctccaa acggctcatc caccaaccta
     5761 gtgctgtacc ggctataaaa agaacaggac aagctagtac cccagcaact cccaatcccg
     5821 cgtaatcggt aggaatgatc ataatcgttg aagcaaaaac tacacctaaa atgaaatgga
     5881 atagcttgct atatgccttt gagaaaatgt aatccatgat ttttgacaat ccaagaacac
     5941 aaagaatccc accaattccg atcggcacaa tcacttcaag tcgtacttct ttaaatccgt
     6001 cagccatcgc tttatacaat cccatataca ccaaaaaatt agaagggctc aatcctggga
     6061 cgatcatacc caaaccaatc aatccgccgg caatcagcca tgttccaaaa ttctgatcga
     6121 cttgcccgtc aaataattga gcgccgtata ataaaaacaa ataagccaga acaaaagtaa
     6181 caaccatgat gatcacatca gaagtatctc ttcctttttt ccctgcttct ttccataacg
     6241 caggaacagt tccagcgata catccgacaa aaaaccataa tatcgttgtt tcatacgcac
     6301 ctaataaaaa actgactaaa aaagaaagta gaaagatgcc tgtcactccg cctagaccaa
     6361 caggcagaaa aaacaaaaca ttttctttga aattttttgt aaggtgggct aaaaaagaaa
     6421 tcagccgctc atacatgcca aagacagctg ctaatgcacc accgctgact cctggcaaga
     6481 taaatcctga accgataaac attcccttca caaaccgtaa catccagtct ttggttgtgt
     6541 accccacttc ttgattttcc attttttgcc ttttttccac tatttgcgca ctccttcttt
     6601 catttaattt tattcatgat tgaacatttc ctgctatttt acttaaagac tttttcatag
     6661 gtctctatta ttttttcatt cattttgaca atatcaggat aaaacatgtt acctccatta
     6721 tgatagagat agccgccatt gtaaagcaag gactggatcc gccaatatcg gtattgtttc
     6781 ccttcctcat ttcctaaaag tgggctcagc acatctttag aatacgcttc tgctaattct
     6841 actgtgtttt ctccgccatg attttttaca taggcaatat aatctttccc aaaattatat
     6901 gcttggacag ctgtccataa atcgcatcct tgtttctttg cttctactat catttccgcc
     6961 aaatatttga caccttgatc aatactgtca gctggattat caatgatctc agcttctcca
     7021 tgcagacttt ccgagctccg catgagatct gtcccttttc cttttgattc ggtcaatatt
     7081 atcgccttga tcaaattctc gtagttttcc atatgataat tttttgcagc tgttgttatt
     7141 tctatttgat agctttccac tcgttttacc gaacgataag ttcttcctcc taaaaacaac
     7201 accgcaccaa taaccgtcag aatgatcatg taaaaaagaa tacggataat agataatcgt
     7261 tttcgcttca tttcatcacc tagttatttt gacatctttt tttatcttac tatttcttta
     7321 tcttcttggc tatttcttcc ttgatttctg tgtacgcctt aagaaaaaat gaattttcct
     7381 gtattttttg tcatcttacg aaaatgatcg ttgtttttca gtaaaaacaa ttgcccaatg
     7441 actgatataa tcgttatact ttacacagta ggtgattatg tgaaaaaaga aaagaaatat
     7501 gcaaaaatgc cagatgggag cgaaatttac tatgaaaaga gcggtcaagg cttccctctc
     7561 tttttactgc atggcaatga cggcagcggc cgcttttttt cagaacaggt ccctgtactc
     7621 gaacgctact ataccgtgta tctagtagat agccgaggac atggtcgttc gacaaacgaa
     7681 gcatctatgt tgaattttca gttaatggcc gaggatctga atacgatcat gttgctggaa
     7741 aaaatcgatc aggcagattt tcttggattt agtgatggag caaatctagc actggtattt
     7801 gccagcagct tccctaaaaa agttcatcga ttgattttaa attctggaaa cacgcttgtt
     7861 aaaggcgttc gtttttctgc cagagtcatc agtaatattc attatgcatg ggtatggtta
     7921 ctctctttat ttcgcccaag tcttcgcaaa aatcttttag ttatcaaact tttgctgcat
     7981 gacatcgggc ttacagaaaa tgatttaaaa aaaatcaact cccccacttt gatcatcgtg
     8041 ggaaaaaaag atgtaatcaa gctaaaacat tctttgtata tagctaaaac tataccaaaa
     8101 gcttcctttg tgcttgtgaa agaacaagga catgaattag ctagaaaaga tcctgaacgc
     8161 ttcaatcgag aagttcttca atttctttct gaaacataac tattaggaat agaaggtgat
     8221 ttatttgtta aaaaatacca tacaatggct gaaaaaccac ctaggactgt tcaaaacaat
     8281 ctttttgatt tctgtcattg tcattattgt cggtgaattg atgtccatcg gtaaaactct
     8341 atctatccag caattaggag aaacgtttgc cactatacct gtatggaaaa gcggacttat
     8401 gctgttgatt ggtcttgtct ctgtgttacc tatgattggt tatgatatta ttttgaatcg
     8461 gatgcttgaa caaaagcaga atcctcgtta cttgtttgag acaagctggc tgatcaatac
     8521 aatcaacaat attgccggtt tcggcgggtt tgttagtgtg gggcttcgct ctgaactata
     8581 tggacaaaag aaagagagca gaaacgtgat ccaagcatta tcgaaagttt tcttgttttt
     8641 gatggctgga ctttctattt acagtctgct ttctttttta cttgtagtct tcacgccagt
     8701 tgctcctttt ttgaagcaat attggatatg gttgatcggc ggcggtctat attttcctgt
     8761 cgtcttttta tttactactt tcaaaaagaa aggattcctt ggtggtacct cacttaaaac
     8821 tcaaggacag ctattgctag tttcattgtt ggaatggacc ggtgtcctgt ttagtttcct
     8881 ttctgttggt tatttaatgg aaatccggat tgatctgtgg caaacaattc cgttattcat
     8941 tgctgcttca gtgataggaa tcgtgtctat gattccagga gaaattggga gtttcgatgt
     9001 aatgatgatt atcgggttgt ccgctattgg tgtgccaaga gaaatagtcg ttgtgtggat
     9061 cttgctctat cgcctgttct actacatcat tccgtttttg attggaatcg tctttttctt
     9121 caaaaatatc ggttccactt ttgatcagcg ttattctggt atccctaaac aattagcaac
     9181 agaaattgcg cataaaatcg tggttgtctt attatacttt tctggaatca tgctagtact
     9241 ttctgccact atcccgcaag cttttacaga gtttcgctgg cttcatagtt tgaacccatt
     9301 gaaatttcat tttattatcc aatttcctag tatactattg ggatttcttt taatcattat
     9361 gggcagaggg atcgcagcac gtgtgaaacg agcatatttg cctacaatct tcttgattgt
     9421 tctagcttta ctttatgttt tattaagtga ttttagtttc acaccggtgg ttttcttgtc
     9481 tattctgctt ctgatcattc ttgcttctaa aaacgaatta tttcgggaac aattgatcta
     9541 ttcatgggag tggcgtacga tcgatggaat cattattggt gcactgtcct tgctttacat
     9601 cgttattggg gtatacaatc tgccggattt ccctcatcgg cgtcaccatt ttatttcctt
     9661 tttcttattt ccttctgaaa agatttggtt ttcgggattg ttggccatca tcgctgttag
     9721 tttcatgatc gttctatttg ttcatttcct tcaaggagaa aagaaacaga ttggcgaagc
     9781 ctttaatgaa gaaaaggccc tgaagatcct tacaacttat ggaggaaact ccgatagtca
     9841 attgatcttc ttaaaagata agcggatgtt tgcctatgaa aaagacggtg aaccaactgt
     9901 tcttctccaa ttcgcttgct tcaataataa atgtattgta atgggtgatc cttctggtaa
     9961 gaaagaagat tttccagaag caatcgaagc ttttatcgaa gaaacagatc gactatgcta
    10021 tttaccagtt ttctacgaaa caagcgaaga gattgttatg attttgcatg aattcggcta
    10081 cgatttcatt aagatggggg aagaagctta tgtagacctg aatagtttta caacttcagg
    10141 gaaaaaaatg aagggcactc gtgctgtctt gaatcggatc gaacgagaag gatttacatt
    10201 tgatgtctta caaccaccat tttctactga gcaaatgagt actttcaaaa atatctctga
    10261 taattggttg ggttcacgaa aggaaaaagg gttttcttta ggctttttct ctgaagatta
    10321 tctacaaaga gcgcctattg cagttgtcaa aaatacccaa gaagaaattg tcgcttttgc
    10381 aacgatcatg cctacttaca cgaacaataa agtaggaacg attgatctga tgcgatatga
    10441 tcctaaaaaa gcaccttctg gcagtatgga tttcttgttc ttgcatttgt ttgcctatat
    10501 gaaagaagaa catatccaat ggttcaattt agggatggcc cctctttcaa atgtcggaac
    10561 ttccagaaag agttttttac aggaaaggat tgcatacttg gtttacgagt ttggttctca
    10621 tttttattct ttccatggat taagagaata taaaagcaag tacgctacaa actgggtctc
    10681 acgttatact ctatattcta gagatagttg gattgcatat gttatgattg ctttgctgat
    10741 tattgataat gcgccagttg agcagacaca aggtagaata agtggtttga aaaaatggat
    10801 acgaagaaa
//
LOCUS       DAYNVV010000081        10574 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.084, whole genome shotgun sequence.
ACCESSION   DAYNVV010000081 DAYNVV010000000
VERSION     DAYNVV010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10574
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.084"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            12..84
                     /locus_tag="ACGXWR_002490"
     tRNA            12..84
                     /locus_tag="ACGXWR_002490"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45..47,aa:Val,seq:tac)
     gene            88..160
                     /locus_tag="ACGXWR_002491"
     tRNA            88..160
                     /locus_tag="ACGXWR_002491"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Lys,seq:ttt)
     gene            168..249
                     /locus_tag="ACGXWR_002492"
     tRNA            168..249
                     /locus_tag="ACGXWR_002492"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:202..204,aa:Leu,seq:tag)
     gene            267..339
                     /locus_tag="ACGXWR_002493"
     tRNA            267..339
                     /locus_tag="ACGXWR_002493"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Thr,seq:tgt)
     gene            351..422
                     /locus_tag="ACGXWR_002494"
     tRNA            351..422
                     /locus_tag="ACGXWR_002494"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:383..385,aa:Gly,seq:gcc)
     gene            439..524
                     /locus_tag="ACGXWR_002495"
     tRNA            439..524
                     /locus_tag="ACGXWR_002495"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:473..475,aa:Leu,seq:taa)
     gene            535..608
                     /locus_tag="ACGXWR_002496"
     tRNA            535..608
                     /locus_tag="ACGXWR_002496"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:569..571,aa:Arg,seq:acg)
     gene            618..691
                     /locus_tag="ACGXWR_002497"
     tRNA            618..691
                     /locus_tag="ACGXWR_002497"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:652..654,aa:Pro,seq:tgg)
     gene            711..783
                     /locus_tag="ACGXWR_002498"
     tRNA            711..783
                     /locus_tag="ACGXWR_002498"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:744..746,aa:Ala,seq:tgc)
     gene            811..884
                     /locus_tag="ACGXWR_002499"
     tRNA            811..884
                     /locus_tag="ACGXWR_002499"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:845..847,aa:Met,seq:cat)
     gene            898..971
                     /locus_tag="ACGXWR_002500"
     tRNA            898..971
                     /locus_tag="ACGXWR_002500"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:932..934,aa:Ile,seq:cat)
     gene            995..1084
                     /locus_tag="ACGXWR_002501"
     tRNA            995..1084
                     /locus_tag="ACGXWR_002501"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1031..1033,aa:Ser,seq:tga)
     gene            1097..1170
                     /locus_tag="ACGXWR_002502"
     tRNA            1097..1170
                     /locus_tag="ACGXWR_002502"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1131..1133,aa:Met,seq:cat)
     gene            1189..1264
                     /locus_tag="ACGXWR_002503"
     tRNA            1189..1264
                     /locus_tag="ACGXWR_002503"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1222..1224,aa:Asp,seq:gtc)
     gene            1266..1336
                     /locus_tag="ACGXWR_002504"
     tRNA            1266..1336
                     /locus_tag="ACGXWR_002504"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1298..1300,aa:Gly,seq:tcc)
     gene            1350..1423
                     /locus_tag="ACGXWR_002505"
     tRNA            1350..1423
                     /locus_tag="ACGXWR_002505"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1384..1386,aa:Ile,seq:gat)
     gene            1448..1535
                     /locus_tag="ACGXWR_002506"
     tRNA            1448..1535
                     /locus_tag="ACGXWR_002506"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1482..1484,aa:Ser,seq:gct)
     gene            1557..1628
                     /locus_tag="ACGXWR_002507"
     tRNA            1557..1628
                     /locus_tag="ACGXWR_002507"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1590..1592,aa:Glu,seq:ttc)
     gene            1651..1740
                     /locus_tag="ACGXWR_002508"
     tRNA            1651..1740
                     /locus_tag="ACGXWR_002508"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1687..1689,aa:Ser,seq:tga)
     gene            1753..1826
                     /locus_tag="ACGXWR_002509"
     tRNA            1753..1826
                     /locus_tag="ACGXWR_002509"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1787..1789,aa:Met,seq:cat)
     gene            1845..1917
                     /locus_tag="ACGXWR_002510"
     tRNA            1845..1917
                     /locus_tag="ACGXWR_002510"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1878..1880,aa:Asp,seq:gtc)
     gene            1921..1993
                     /locus_tag="ACGXWR_002511"
     tRNA            1921..1993
                     /locus_tag="ACGXWR_002511"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1954..1956,aa:Phe,seq:gaa)
     gene            1998..2068
                     /locus_tag="ACGXWR_002512"
     tRNA            1998..2068
                     /locus_tag="ACGXWR_002512"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2030..2032,aa:Gly,seq:tcc)
     gene            2081..2154
                     /locus_tag="ACGXWR_002513"
     tRNA            2081..2154
                     /locus_tag="ACGXWR_002513"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2115..2117,aa:Ile,seq:gat)
     gene            2166..2237
                     /locus_tag="ACGXWR_002514"
     tRNA            2166..2237
                     /locus_tag="ACGXWR_002514"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2199..2201,aa:Glu,seq:ttc)
     regulatory      2426..2505
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SMK box riboswitch (SAM-III) riboswitch; SAM
                     riboswitches modulate the expression of downstream genes
                     in response to levels of S-adenosylmethionine; SMK box
                     riboswitch shares no known similarity to SAM-I and SAM-II;
                     Derived by automated computational analysis using gene
                     prediction method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            2503..3696
                     /gene="metK"
                     /locus_tag="ACGXWR_002515"
     CDS             2503..3696
                     /gene="metK"
                     /locus_tag="ACGXWR_002515"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFK0804002.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3826..5298
                     /locus_tag="ACGXWR_002516"
     CDS             3826..5298
                     /locus_tag="ACGXWR_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFK0804003.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            5381..6169
                     /locus_tag="ACGXWR_002517"
     CDS             5381..6169
                     /locus_tag="ACGXWR_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFK0804004.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(6236..6904)
                     /locus_tag="ACGXWR_002518"
     CDS             complement(6236..6904)
                     /locus_tag="ACGXWR_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HFK0804005.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            7019..8731
                     /locus_tag="ACGXWR_002519"
     CDS             7019..8731
                     /locus_tag="ACGXWR_002519"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0804006.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8734..10506
                     /locus_tag="ACGXWR_002520"
     CDS             8734..10506
                     /locus_tag="ACGXWR_002520"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0804007.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         3033 a         1926 c         2453 g         3162 t
ORIGIN      
        1 aagttatcca tggaggttta gctcagctgg gagagcatct gccttacaag cagagggtca
       61 gcggttcgat cccgttaacc tccatatgag ccgttagctc agttggtaga gcatctgact
      121 tttaatcaga gggtcacagg ttcgagccct gtacggctca tatttttgcg ggtgtggcgg
      181 aattggcaga cgcactagat ttaggatcta gcgccttacg gcgtgggggt tcaagtccct
      241 tcacccgcat aatttaagtt ttacatgccg gcttagctca gttggtagag catctgattt
      301 gtaatcagag ggtcgagggt tcaagtcctt tagccggcat ctttaaacac gcggaaatag
      361 ctcagtggta gagcaccacc ttgccaaggt gggggtcgcg ggttcgaacc ccgttttccg
      421 ctttgccaaa gcaatcgcgc cggggtggcg gaactggcag acgcacagga cttaaaatcc
      481 tgcggtgagt gatcaccgta ccggttcgat tccggtcctc ggcatttcaa atatgcgccc
      541 atagctcaac tggatagagt gtttgactac ggatcaaaag gttaggggtt cgactcctct
      601 tgggcgcgtt aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa
      661 ggggtcgcag gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag
      721 ctcagctggg agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct
      781 ccatttcatt taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc
      841 ggttcatacc cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga
      901 cctttagctc agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc
      961 tacaaggtcc attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag
     1021 ggaacggtct tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc
     1081 tcctttttca tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga
     1141 aggtcgtagg ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg
     1201 taggggttaa catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc
     1261 gccatgcggg tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg
     1321 attctcgtca cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg
     1381 cctgataagc gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat
     1441 tggttttggg gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg
     1501 aaaccggcgc gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc
     1561 cgttggtcaa gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt
     1621 acgggtcatt aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa
     1681 cggtcttgaa aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct
     1741 ttttcatatt atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt
     1801 cgtaggttca aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg
     1861 ggttaacatg cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt
     1921 ggctcggtag ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt
     1981 ctgtcccgcg ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt
     2041 gtcgcgagtt cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt
     2101 tagagcgcac gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt
     2161 ttattggccc gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc
     2221 gaatcccgta cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga
     2281 atgattttaa aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga
     2341 cagttctaat gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag
     2401 aaaactgttt tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg
     2461 gagatgcctt gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta
     2521 tttacatcag aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat
     2581 gcaatcttgg atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct
     2641 gtaacaactg gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt
     2701 caaaaagtcg tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt
     2761 gatggagata cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa
     2821 ggagttgatg aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt
     2881 ggtgctggtg accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg
     2941 cctttaccaa tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca
     3001 aatgaattaa cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat
     3061 caaggacaac cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta
     3121 gataatgaaa caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct
     3181 gaattattag atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt
     3241 ggtcctcaag gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt
     3301 tatgctcgtc atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct
     3361 gccagctatg ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa
     3421 gcagaagtac agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat
     3481 actttcggta ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc
     3541 gatcttcggc cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa
     3601 acagctgctt acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac
     3661 aaagtagatg cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc
     3721 caagtggtgg ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt
     3781 atttatctat ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca
     3841 aatgttactt tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt
     3901 acaatcgtaa caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg
     3961 aactgggtat tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa
     4021 cttgcggata aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc
     4081 ggttcgttat tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt
     4141 caagggatgg gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat
     4201 tctattgaaa agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt
     4261 gtttttggac cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt
     4321 tttatcaatg tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa
     4381 ccaaaaatca tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc
     4441 atgcttgtct cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt
     4501 gtttctgctt tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa
     4561 agagctaaag atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc
     4621 aacttggctg cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg
     4681 tggatgcaag gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta
     4741 tcactagtct ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact
     4801 cattgggtct tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt
     4861 atgcctttca gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc
     4921 ttaggtgtga ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag
     4981 cttggtgtag caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt
     5041 tctatttttg gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta
     5101 acaaatgatg cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat
     5161 gcggatattt tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta
     5221 gttggcttgt tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt
     5281 ggtaaaataa aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa
     5341 agttattcaa aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa
     5401 tatttattcg aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac
     5461 aaaaaaggtg attggcacca gttcagagca agagacaacg gatatacctg ttttatattt
     5521 acttcatgga atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta
     5581 tgtagcaaac tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga
     5641 tacagtttat gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca
     5701 tgaattattc ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat
     5761 gggcggatat ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat
     5821 ctctctttca ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa
     5881 agcatctttt tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga
     5941 tccgcaatac ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat
     6001 ggcttgtggg gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca
     6061 ggaacaaggc ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg
     6121 ggaccaatgg attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct
     6181 taaaaagata gctcctatag agatcacaaa catagtgatc tctataggag cttttttact
     6241 gctcgttttc tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg
     6301 ttagaaagag tgctttttca ttcaattctg catgggactg catactttct ttaaatccct
     6361 ctaattgatt ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat
     6421 ttccgtccat aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa
     6481 tcaataaatt gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac
     6541 gaacaagtaa ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag
     6601 tattgatttc taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca
     6661 tatactgcag caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt
     6721 ccattgtttc agccattttt tgcaagagct gttgtttgtt tttgaaatac caatataaag
     6781 caggtgcttg aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt
     6841 gtgtttcagc caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt
     6901 ccattttatc aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt
     6961 ctaattttac agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat
     7021 gaaattaatc ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc
     7081 cgtagcagtc atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga
     7141 agctattatt acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct
     7201 ggctttgcta ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca
     7261 aggcgtaagt gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg
     7321 aaatatcgaa cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca
     7381 aatccaaaat ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat
     7441 tggtgccttc attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct
     7501 tatcgttacg gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat
     7561 gatcattcaa aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat
     7621 tcgtgtagtg aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag
     7681 tgaggactta acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc
     7741 cttcatgctg gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt
     7801 taaagatgat cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat
     7861 tatgatggca atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc
     7921 gctgaagcgg attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc
     7981 agaacaagag ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga
     8041 ggatacagat acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat
     8101 cgtcggggcg actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga
     8161 tccgacagaa ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag
     8221 tttaagacaa acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc
     8281 tcaaaacttg cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc
     8341 tattgctcaa gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga
     8401 agaacgtagc agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt
     8461 tatcggtaat ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc
     8521 tgaaaagctg gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat
     8581 cgcacaaaaa attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag
     8641 attagtcggc gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat
     8701 ctttgaaact caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa
     8761 tttttctatc actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg
     8821 atcattgcta cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa
     8881 ttagctaatt acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct
     8941 gtaatatgga aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt
     9001 attttgttca cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac
     9061 aaattggaaa aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt
     9121 cgttttacca gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc
     9181 atcacgaatg ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag
     9241 ttagcttggg ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc
     9301 cgcaaagcac ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat
     9361 atggatgaaa aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg
     9421 attgaaggat tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct
     9481 tattctggtc tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt
     9541 atctttttcg gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc
     9601 ttagttgtga cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca
     9661 tctggataca gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt
     9721 gatgaaaaag atgaagtcaa accagaaaac ggtaaagcat ttgatggtgt tgaaaaaggt
     9781 cttgcgttgc agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc
     9841 tcgatcaatg tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa
     9901 acgacgatca tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc
     9961 gatggaatag atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt
    10021 ttgcaagaat ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg
    10081 gacgcttcag atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc
    10141 atgacgttag aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca
    10201 ggtcaaaagc agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt
    10261 ttggatgaag caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg
    10321 gatgaagcaa tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg
    10381 aatgcagata gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcat
    10441 gagttattag cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa
    10501 agttaaatta aaagaacctc gttataacgg ggttcttttt atatatttta tgttgtttgt
    10561 ttttataagg ggca
//
LOCUS       DAYNVV010000082        10552 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.085, whole genome shotgun sequence.
ACCESSION   DAYNVV010000082 DAYNVV010000000
VERSION     DAYNVV010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10552
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.085"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            33..656
                     /locus_tag="ACGXWR_002521"
     CDS             33..656
                     /locus_tag="ACGXWR_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804008.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1106..2155
                     /gene="trpX"
                     /locus_tag="ACGXWR_002522"
     CDS             1106..2155
                     /gene="trpX"
                     /locus_tag="ACGXWR_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HFK0804009.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2152..3033
                     /locus_tag="ACGXWR_002523"
     CDS             2152..3033
                     /locus_tag="ACGXWR_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0804010.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3036..3806
                     /locus_tag="ACGXWR_002524"
     CDS             3036..3806
                     /locus_tag="ACGXWR_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0804011.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4085..4939
                     /gene="aroE"
                     /locus_tag="ACGXWR_002525"
     CDS             4085..4939
                     /gene="aroE"
                     /locus_tag="ACGXWR_002525"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFK0804012.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5117..6280
                     /locus_tag="ACGXWR_002526"
     CDS             5117..6280
                     /locus_tag="ACGXWR_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFK0804013.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6397..6807
                     /locus_tag="ACGXWR_002527"
     CDS             6397..6807
                     /locus_tag="ACGXWR_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFK0804014.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6981..9209
                     /gene="topB"
                     /locus_tag="ACGXWR_002528"
     CDS             6981..9209
                     /gene="topB"
                     /locus_tag="ACGXWR_002528"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFK0804015.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9380..9664
                     /locus_tag="ACGXWR_002529"
     CDS             9380..9664
                     /locus_tag="ACGXWR_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804016.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9824..10060
                     /locus_tag="ACGXWR_002530"
     CDS             9824..10060
                     /locus_tag="ACGXWR_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFK0804017.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10057..10455
                     /locus_tag="ACGXWR_002531"
     CDS             10057..10455
                     /locus_tag="ACGXWR_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HFK0804018.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3680 a         1770 c         2230 g         2872 t
ORIGIN      
        1 aataaaaaat aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat
       61 cgagagtaca agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt
      121 attttcgacg tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt
      181 tattgccgga aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa
      241 ccagcaaatt gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg
      301 cgatatcggt gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt
      361 ttaatgatcc tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt
      421 atgatgtaca tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt
      481 tctttgatgg aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt
      541 ttgataagga gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag
      601 aagaagaatt ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca
      661 ttggcgcgat gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg
      721 tttgatcttc aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt
      781 cgattagact taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt
      841 atttcagcag aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg
      901 agactttccc atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga
      961 catgaacatt gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga
     1021 ccgctttggc cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa
     1081 agattgactt tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat
     1141 tattttagtt tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag
     1201 tacttcgacg aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca
     1261 tccggcatta gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa
     1321 agaaggagaa aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc
     1381 cacaatgagt caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc
     1441 tgccgctcaa tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac
     1501 ggatcctgtg ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg
     1561 tgtttctgat cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa
     1621 tgcaaaaaaa gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc
     1681 acaagcagaa gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc
     1741 cactaatgag attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt
     1801 tccattagat aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc
     1861 aaatatcccc gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat
     1921 cgggatcaat caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag
     1981 tggaaaagaa aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat
     2041 caatcaatct caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc
     2101 caaaatcatt acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta
     2161 tcagctattt cacaaggcat gctttgggca atattaggat tagggatttt catgacttat
     2221 cggatcttag actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc
     2281 tgtgtgacag ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt
     2341 gctggcatga tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt
     2401 attttagcag ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga
     2461 acaccaaatc tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg
     2521 ttacctgatt actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct
     2581 gtactgctat tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac
     2641 gaaacgatgg ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact
     2701 ttgtcgaacg gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca
     2761 gatgtaaata aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa
     2821 gtgatcttcc aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc
     2881 atttatcagc tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag
     2941 ttgttctccg ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg
     3001 aacttaaaaa cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa
     3061 atggcagaaa agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta
     3121 accttacaat cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa
     3181 gcacactgtt caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta
     3241 aagatcagct gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt
     3301 tccaagaccc caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg
     3361 cacaaaaaag aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag
     3421 attttttcag actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag
     3481 cgggtgaatt atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag
     3541 ctcctgagtt actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag
     3601 cattaatgcg attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca
     3661 cgcatcgaat ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga
     3721 aaatcgttca agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc
     3781 agttctttga agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact
     3841 tgaaaactca ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa
     3901 catatttggg tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt
     3961 ctttgctctg acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc
     4021 gtactttttc gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa
     4081 taagatgatt tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag
     4141 tttatcccca ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt
     4201 agctttccaa gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga
     4261 tatgttaggt gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga
     4321 ggtaagccag gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg
     4381 tttgattggc tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat
     4441 ttcgatcaaa aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac
     4501 tgttcaagct gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac
     4561 attcgctcaa gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa
     4621 agttcgtgac tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct
     4681 agtcaatgca acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat
     4741 aagcatgatg catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg
     4801 tttattaaaa gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat
     4861 ctaccaagga gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat
     4921 tgaaaagctg tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg
     4981 gtctcaagaa aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat
     5041 tatcaaaaaa tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa
     5101 acgaggagga accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa
     5161 acctctgaag cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat
     5221 ggaaaatgag gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt
     5281 gaaccaatac gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa
     5341 taaaaaattt ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc
     5401 gtggaaaaaa atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt
     5461 ttttattggt aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac
     5521 ctttcatggg caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac
     5581 acgcggagaa gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc
     5641 ccataagccg aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg
     5701 acaaaataag atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt
     5761 agtagaaaat tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga
     5821 aaaagtgatc gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa
     5881 tctggatggt gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca
     5941 gtacgcacgt ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca
     6001 agtaatgaac gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta
     6061 tgcagctggt aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa
     6121 aaacctcttt tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga
     6181 cggttcgtgg aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca
     6241 aatgaatcaa tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag
     6301 aagctgcgca aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc
     6361 ttatggtaga tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa
     6421 aatgagtcgc gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt
     6481 atcaccacat acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa
     6541 aatctaatca cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg
     6601 ccagaaggaa ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca
     6661 agaaatgaag aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag
     6721 atgccactgg atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc
     6781 atcaactggc agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa
     6841 gcagcaaacg gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt
     6901 atcttttttt tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat
     6961 taagtaacgg aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa
     7021 aagcctatgc cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg
     7081 atccattgtt tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg
     7141 ttgctccagg agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt
     7201 tcccagaaac cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa
     7261 aacgagaatt gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg
     7321 aagccatcgc gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt
     7381 tacgtttatg gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc
     7441 aacctggaaa gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt
     7501 ggctgattgg aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg
     7561 atggcagttt ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc
     7621 aagaagaaat caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga
     7681 caaacaaagg gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag
     7741 agttaacgaa ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc
     7801 ttgaagttac gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt
     7861 tgcagacaaa gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc
     7921 aaggattgta cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag
     7981 aaaatgagca tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag
     8041 aagaagtaca gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc
     8101 aagaacatca tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc
     8161 tttccaaatt acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg
     8221 ctgcagatta tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa
     8281 aaagcatcgg aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa
     8341 aaaagaaaga agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac
     8401 tgaaaagtat ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca
     8461 cagcaatgaa aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag
     8521 aagtagaagg aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga
     8581 agcattacat cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt
     8641 gtaaggcagt agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag
     8701 ggtacttgag aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca
     8761 aaaaattcat cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt
     8821 cagatgagat tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag
     8881 gaagatgtcc aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct
     8941 tgaatccgga atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa
     9001 cgaatctcag agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg
     9061 gtaaaaaagg gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt
     9121 cttttccatg gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa
     9181 gaaaaaataa tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt
     9241 ccgaaaagtg agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa
     9301 cgttggggta ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca
     9361 ttcattttta aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct
     9421 aaagtatcct gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc
     9481 accaacgttg attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca
     9541 taaaacgaca agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc
     9601 ggctatgatc attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg
     9661 ttaagaatac gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt
     9721 tcgtaagaaa aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa
     9781 tgtacttact atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa
     9841 gtataaaatt agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga
     9901 attcatgggt gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt
     9961 acgaatgatc aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa
    10021 tcaatatgaa gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa
    10081 attatcaaaa tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta
    10141 aaagatgcaa atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa
    10201 gaactctatc ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa
    10261 catccttttc ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa
    10321 ttgaataatt gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt
    10381 accactagtt cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa
    10441 accgcaataa aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa
    10501 ggaatatgct gattttttta tgtttaatca tacaaaatag ttttttcata aa
//
LOCUS       DAYNVV010000083        10243 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.086, whole genome shotgun sequence.
ACCESSION   DAYNVV010000083 DAYNVV010000000
VERSION     DAYNVV010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10243
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.086"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            160..390
                     /locus_tag="ACGXWR_002532"
     CDS             160..390
                     /locus_tag="ACGXWR_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HFK0804019.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            487..1788
                     /gene="murA"
                     /locus_tag="ACGXWR_002533"
     CDS             487..1788
                     /gene="murA"
                     /locus_tag="ACGXWR_002533"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFK0804020.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1801..1977
                     /locus_tag="ACGXWR_002534"
     CDS             1801..1977
                     /locus_tag="ACGXWR_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFK0804021.1"
                     /translation="MSNQRYIILTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2112..2408
                     /gene="yidD"
                     /locus_tag="ACGXWR_002535"
     CDS             2112..2408
                     /gene="yidD"
                     /locus_tag="ACGXWR_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HFK0804022.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFQLTRNKKDKKEPDYKKVVKNTSSTER"
     gene            2592..3059
                     /locus_tag="ACGXWR_002536"
     CDS             2592..3059
                     /locus_tag="ACGXWR_002536"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFK0804023.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVAPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3144..4028
                     /locus_tag="ACGXWR_002537"
     CDS             3144..4028
                     /locus_tag="ACGXWR_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFK0804024.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNSYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4142..4378
                     /locus_tag="ACGXWR_002538"
     CDS             4142..4378
                     /locus_tag="ACGXWR_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HFK0804025.1"
                     /translation="MMSKKNKDVEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4466..4546
                     /locus_tag="ACGXWR_002539"
     tRNA            4466..4546
                     /locus_tag="ACGXWR_002539"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4500..4502,aa:Tyr,seq:gta)
     gene            4553..4624
                     /locus_tag="ACGXWR_002540"
     tRNA            4553..4624
                     /locus_tag="ACGXWR_002540"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4585..4587,aa:Gln,seq:ttg)
     gene            4749..4919
                     /locus_tag="ACGXWR_002541"
     CDS             4749..4919
                     /locus_tag="ACGXWR_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804026.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            5139..5846
                     /locus_tag="ACGXWR_002542"
     CDS             5139..5846
                     /locus_tag="ACGXWR_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFK0804027.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5906..6550)
                     /locus_tag="ACGXWR_002543"
     CDS             complement(5906..6550)
                     /locus_tag="ACGXWR_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HFK0804028.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6677..6964
                     /locus_tag="ACGXWR_002544"
     CDS             6677..6964
                     /locus_tag="ACGXWR_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804029.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7072..7392
                     /locus_tag="ACGXWR_002545"
     CDS             7072..7392
                     /locus_tag="ACGXWR_002545"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFK0804030.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7473..8786
                     /locus_tag="ACGXWR_002546"
     CDS             7473..8786
                     /locus_tag="ACGXWR_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HFK0804031.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEIAKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            8783..9502
                     /locus_tag="ACGXWR_002547"
     CDS             8783..9502
                     /locus_tag="ACGXWR_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HFK0804032.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            9630..10181
                     /gene="raiA"
                     /locus_tag="ACGXWR_002548"
     CDS             9630..10181
                     /gene="raiA"
                     /locus_tag="ACGXWR_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HFK0804033.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADATALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
BASE COUNT         3415 a         1693 c         2187 g         2948 t
ORIGIN      
        1 ttgtctcagt cccttttttt gcatattttt agcatttatt tcctaaaaaa tgtaagggga
       61 ttcctatatt tttaagtata cttgtttttc cttttataca ttttatggta ttatcatttt
      121 attagttatt ataaaacaat cgttagaaag gacgtcatta tgcaagtata cggaattgat
      181 gcggtgcttc gaatcgtgag tcatttggcg tttatctact tagccttctg gtctttacgt
      241 tcgttacgca ttgaaacttt tttcagacca atgcataata cgcaaattag aatggcaatc
      301 gtactttttt caattttttt agggtacact gcaagtaatt ttttcttaga agttatcgct
      361 ttatgccgaa atcttttcgt tagcctgtaa attttaaaaa aaggtactat tttaaaagca
      421 aggatgttat aatagaaaag attttgagta agtgtatgct cattggaatt ttttggaggg
      481 aacaacatgg aagagatcat cgtaagaggt ggcaatcaat taaatggaac agtaagaatt
      541 gaaggagcta aaaatgctgt tttgcctatt ttagctgcta gtttgttagc agaagaaggt
      601 attacgacat tagacaacgt tccgattctt tctgatgtct tcactatgaa tcaagtgatt
      661 cgtcacttaa acgtagatgt agattttgat gaacaaaaga atcaagtaac aatcgatgct
      721 tcaagacaat tagaaatcga agcgccttat gagtatgtta gtcaaatgcg tgcttcaatc
      781 gttgtgatgg gtccgctact tgccagaaat ggacatgcaa aagtagctat gcctggtgga
      841 tgtgcgattg gtaaacgacc aatcgatttg catttaaaag gatttcaagc tttaggagca
      901 aaaattattc aaaaaaacgg ctatatcgaa gcaattgcgg atgaattgat cggtaacacg
      961 atttatttag atttccctag tgtaggtgct actcaaaata tcatgatggc tgccgtaaaa
     1021 gcaaaaggaa caaccatcat tgaaaacgta gctcgcgaac cagaaatcgt tgatttagca
     1081 aacattttga ataaaatggg cgctcaagtc tatggagctg gtactgaaac aatgcgtatt
     1141 gaaggcgtgg atcatttaca tgcagtcaac cactcaatcg tacaagatcg tatcgaagca
     1201 ggtaccttta tggttgctgc tgcaatgaca caaggcaatg tgctgattgc agatgctatc
     1261 tctgaacata accgcccatt gatttctaaa ttgatcgaaa tgggtgcaga aatcattgaa
     1321 gaagaaggcg gagtccgtgt catcggacca aaacatatct tacctacaga tgtaaaaacg
     1381 atgcctcatc ctggtttccc tacagatatg caagctcaaa tgacagctat ccaattagtt
     1441 gcagaaggta caagtgtagt gactgaaaca gtgtttgaaa atcgtttcca acatttagaa
     1501 gagatgcgcc gtatgaacgc tcatgtcaaa atcgacggaa atgtagcaat catggatgga
     1561 aaccatgaat tgcaaggtgc agaagtatat gcaacagact tgcgggcagc agcagcatta
     1621 gttttagctg gcttgaaagc aaatggaatc acacgtgtgc gtaacttgaa ttatctagac
     1681 cgtggatatt ataatttcca tatcaaacta cagcaattag gtgcagacgt tgaacgtgta
     1741 gacatggatc aaacttctgc tgaaaaaaca gcacaaacga ttgcttaagg aagtggctga
     1801 atgagtaacc aacgatatat catattaact ttgataaaga ttttagtggt gatcttattg
     1861 cttatccttc tttttgtggc cggaacgatg atcggatatg gtgtcatcgg tggcggcaat
     1921 ccatttaaag tattccagcc aagtttgtgg attcatattc gagacttttt tcattgataa
     1981 ataagaatca cagtggttct agtcgatatg aagtgagcca tgaagcagaa catgacaaaa
     2041 gaaaacagaa gggaacgttg acgttagtcg cgatcccttt ttttagtaaa agaaaagaag
     2101 gaatctaatt gatgaagaag atattgattt atttagttag aggatatcag cgctttattt
     2161 cgcctgcatt tccacctagc tgccgttatt acccaacctg ttccaattat atgataaaag
     2221 caattcaaac ccatggtgca ctaaaaggga cggtaatggg gactgcacgg atcttacgct
     2281 gtcatccttt tgtcaaaggc ggtatcgatt atgtaccatt gacattccaa ttaacgcgaa
     2341 ataagaaaga taaaaaagaa ccagattata aaaaggttgt gaaaaatacg agtagcactg
     2401 agcgataaag aaacaatttg gaaaatagct tcttatattt tgcaaaattg tgagttattg
     2461 ccgaagtgtt ggattttgaa caccgtcaaa aaaaggttgt gaaaaatacg ggtagcactg
     2521 agcgataaag aaaaagagga aaattattgt caaagtaaca actccgcaac tacttatatg
     2581 ggggacaaaa aatgatcgaa gaactaaaca agaaagattt accatggtcc ttgttattag
     2641 atgcagatcc tgataaagaa aaagttcaag tatatgtttc cagagggagt ggctggatat
     2701 ggaaagaaaa agaaaaaaca ataggtgtac tgatctatgt ggcaagggaa aaagaatacg
     2761 aaatcgtcaa tgtagcagta gccccaacgt atcaaggaaa ggggattggc ggaaaattac
     2821 ttgagacagc ttttcagaag ctttcacaac tcgcttccag tcaaactcag atcatcatac
     2881 gaaccggcag tactagcagt gcggcgttac atctctatca aaaaatgggc tatgtggaga
     2941 ttggtcgagt caaagactat tttatccatc attactctga gcccattttt gaaaatggag
     3001 atcaattaag ggatcaagta attttagcaa ttcacttacc taaaaatagc tttaactaat
     3061 aaactttcaa ttcgagaaaa tgctttcaaa tgctaaatag atacattaca atagctttag
     3121 caaacaaaaa ggagaatatt tttatgggaa tattagtttt tgattttggt ggatcggctg
     3181 tcaaatatgg ttgttgggat ggcaaagaga ttaaaggtaa gggacaattt gcaacgcctg
     3241 aatcttggga agaaatgaaa gcgcaattat ttcaagttta taaaaaaata ctcgtttctt
     3301 ttgaagtcga aggaattgga atcagctctc ctggagtagt gaataatgag aaacaggtga
     3361 ttgagggaat cagtgcgatt ccttatattc atggatttaa tattttccga gatttggaaa
     3421 ctctgtttca actcccagta acgattgaaa atgacgccaa ctgtgccgga atggctgaat
     3481 tttatgaagg tgctgcccgt gattatcaag atgttgcttt tgttgtggca ggaactggga
     3541 ttggcggggc gttgttcacg aaaggacaaa tcaataaagg ggcacatctt tatggtggag
     3601 aatttgggtt gatgttctta aatggcgata agacattcag taaacttggt acagcggtac
     3661 agatggcttg gcgttattgt gaacgcaaag gtctcgataa aaattcttat accggaaaag
     3721 atgtctttga attagcagaa actggagatg caatagcaaa agaagaagtt gagagttttt
     3781 atacgtatct tacaaaggga ttattcagta ttcaattttc gtttgatcca gaagtgatcg
     3841 tattaggcgg cggtgtttct gcaaaagaag ggctcattga tgagatcaaa agccgaatga
     3901 agaagctgac agaacaattc gatctgcatg atttcgaacc gcagatttta ttatgtgaat
     3961 acagaaacga tgctaatctt gtaggtgcag cagcaaacta tctcgctgta cgtcaagggg
     4021 agaattaaga gctttagaga aggtgcagct tgcataaaag aagtgaatga aatgaatagg
     4081 agatttttac ctaaggaatg ttttatttgc tgcagtatga taaaatatct gagaggtgaa
     4141 aatgatgtca aaaaaaaata aagatgttga agtgcgtata gaagaagtga aaaaagatat
     4201 caaaggtaag aattatgaag tcactcagtt atttataggg aaaaaaatga ttggtgagat
     4261 cttagcctat gggccaaaag aatatgaaat tttctttggt gaagaagatt ttggaaaaga
     4321 aaaaagtctt gaaaatgcga tagaaacagt gattcgacac tggaatctgc acgaataaaa
     4381 aaatatcaaa aaaactttca ataaagggtt gcaaaaatct ggaaaattag gtattataac
     4441 taagtcaggt tgatacaaac ctttcggagg agtagcgaag tggctaaacg cgacggactg
     4501 taaatccgtt ccttagggtt cagtggttcg aatccactct cctccatttc attggggtat
     4561 agccaagcgg taaggcaagg gactttgact ccctcatgcg ttggttcgaa tccagctacc
     4621 ccagtatacc acaatcgtaa gctctcgtta gttcgagagc tctttttttt gctttgctac
     4681 cttgttcctt gaagattctg ctgatttaag atagagttaa gttaactaca agaattggag
     4741 ggatccacat gaaatggaaa gaaaaagtag acgaagcagc tgaaaagtta tatgatttgg
     4801 tcaaatcaga aaaatacaat attgaagtga atattccgaa aaaaggcgga aaagcggtcc
     4861 aggtaaaatc aaaacgccca acgaatcata caaaaaaatg gatggctaaa aaccgctaat
     4921 aataacaaaa gatccataag tcggcatttt catcgatttt agggtctttt gttattttct
     4981 aggttgaaca tatctaaaaa attgtttctg acaataggag taggaagaac gatgtgtgtc
     5041 taaatcctct gttgatggat agaaaccttt atctttttca gttgtgaatc aggtatatac
     5101 cagttataat agaagaaacg aaaggacggg tgtacgttat gtcgaatcaa ttacctgtat
     5161 atatacagat tcatgaccaa ttaaaaaatg aaatcgaaca aggtatatgg aaagtcggag
     5221 accgtcttcc ttcagaaaga gaattagcag tgaaattcaa tgtcagccgt atgacgttga
     5281 gacaagcaat tcaaaacttg gcagatgaag gaatcttaga aagaaagatc ggttcgggta
     5341 catatgttgc gcgagaaaaa gtacaagaaa aaatgtctgg tgcaacaagt tttacagaaa
     5401 ttatggaatc gcaaaatcga gtaccgtcta gtcggacaat ctcttatttc ttgacttcgc
     5461 caagctcaag tgaaatggaa aaactaaact tgagtaaaga tgacacgatc ttgcgaatgg
     5521 aacgtattcg tttcgcagat gatgtcccta tttgttttga agttgccagt gtgccacaaa
     5581 agctgatcga tggctacagc aaagcagaga ttactgaatc gttgtatcgc acgctagaag
     5641 aaaaaggcgg gaaaaagatc ggtccagcga atcaaacgat tactgctgtg ttggcttctg
     5701 agaaaattgc tgactattta gaggtaaaac gaggagatgc agttcttcgt ttgcgccaga
     5761 tttcttattt tgaagacggt acgccgtttg agtatgtgcg tacgcaatac gtaggaaatc
     5821 gttttgagtt ttatttggaa aaataaaaaa caggtgatcc ctgattcctt acttagaaat
     5881 aaaagagaat cagaatcacc tgtttttata tatgatcagt taccagttgc tcgtgataag
     5941 aaacaggacc ctcttcaaat tggacttgtc cgttcagcag ctcaatgatg gattctttaa
     6001 agtggtcagc acttttttca tctacagcac agatgacgct aacttgatca gtatattgga
     6061 tttcttttat aaaaaaatgt tggagttcaa gataattctg taattttcct agttgcggat
     6121 acgtgatcat cacagagatc tcctgttgca aggtaccttc tacgattcca atgtcagaca
     6181 atgcttgaga gacagcatga gtgtatgctc gtattaatcc gcctgtgccg agtttcgttc
     6241 ctccaaaata tcgagtgact actgcagcta cattgatcag ttgatttttt ttgaggactt
     6301 ccaacatcgg tacgccagcc gttccacttg gttctccatc atcgctgctt cgctggattt
     6361 catttttttc tccaatgatg aaggcgctgc agttatggtt cgctttccaa tgttcttttt
     6421 ttatttcttg aatgaaactt tttgcttggt cctctgattc tattcgtcta agagaacaga
     6481 taaagcgtga ttttttgatc tcaatctcac tttgtccatt ttcttttatt gtacgatagc
     6541 gctcgatcat cttgtcacct ctttttttca ttttctttat tcagtataaa taaagttcta
     6601 ggttgtttca acactgtaac ggttgcgcaa tcgctgtagt atgcgataat aaagacaaag
     6661 gtaggtggat ctggggatgc aggaacgaat gaaaaagtac gatgcaatta cgcattattt
     6721 gaagaacaat ggcggctctc aagtaacgtt gacctttacc caatttgacg aactgctgtt
     6781 tcccagtaac ggacttccca aaacagcaag ggaaagtaca gattggtggg caaatgatta
     6841 taaacaccct gaaaaaggtg cctatggctg gataaatgca ggctatgaag tagttgtcat
     6901 caatttggac aaagaatatg tcgtgttcaa taaattagtg aaatctagtt ggctatttga
     6961 ttaaataaac cgcgtttaga aaacgttgac aaatttcttt ctttttatat aatagagtaa
     7021 cagacgcgaa gaaaacgttt gcgtagtttg ttttaaaaag gagagaaaag tatggctaaa
     7081 aaaacaatca tgcttgtatg ttcggctggt atgagcacaa gtttactagt aacaaaaatg
     7141 caaaaagctg ctgaagcaaa aggaatcgac tcggatattt tcgctgtgtc cgcttctgac
     7201 gcagataaca atcttgcaaa taaagatgta gatgtactgt tattaggacc tcaagttcgc
     7261 tttatgaaag ctgattttga aaaacgtctg gaaccaaaag gcattccttt agacgtcatc
     7321 aatatggctg attatggtat gatgaatggc gaaaaagtgt tagatcaagc aatcacgctc
     7381 ataggtgaat aaatagaaca gtataactat cgaacaagcg atccaaaaaa tagatcgctt
     7441 gttttttcgt atattttttt agggcgaata atatgaatca tttttggggt agaaggcttc
     7501 tgacgagaga tattaaagca atagactgtg aggaggtaaa tttaccaaat tatgagaaga
     7561 tcgcagcagt ggaacgtttg ggcaactgga ttctttgtca tcgctgtgga atgaggacgt
     7621 ccgtcattga tggacagctt gcagattacg gttatttttg tacacattgt ctatatttag
     7681 ggcgatgcga cactcaacaa gatttatatt tgtttgatca gcctgaagca aaacctcgag
     7741 aagtcgtctt tttttggaca ggacagctta ctgaaaaaca aacggaaatc gcaaagagaa
     7801 tactttgcca ttcagaaaaa agacatcatc ttatttgggc tgtaacaggt gcagggaaaa
     7861 cagagatgct ttatcctatt ttagtggaaa ctttaaaagc tggaggaaga gtagcgattt
     7921 gtacaccgcg agtcgatgtt tgtaatgaat tgtttttacg ctatcgttat gtttttccag
     7981 aagaaaaaat cacgttgctc catgggaata cagcaacggc ttataccttt acttcttttg
     8041 ttatctgtac gattcatcag ctataccgtt tttatcggtc ctttgattta atagtgatcg
     8101 atgagatcga tgcgtttcct tataacgggg atgcaggatt agctcatgct gtgcaaacag
     8161 cgattaaacc agacggacga ttcatctact taagtgccac acctgataaa aagttactaa
     8221 aggaaatcaa gcagacgttt gacatccaca aacttgcttt gcgctttcat cggcgtttac
     8281 ttcctgaacc cgtcttggtt ttcatgaata attggcgaca aaaatgcaag aacaagaaga
     8341 agataaaatc tttggtgcgg atcattcatc aattaattaa agaaaaccat atccttttat
     8401 tttgtccaag tatcacgatg atgcatcgtt tgaaagccac acttcaagag gctcttccga
     8461 gatatgagat cacagatgtt tcttcaagag acaatcagcg ggcggaaaaa gtccagaaaa
     8521 tgcgagaagc aaaatatgac atactgttaa ccacgatgat ccttgaacgt ggagtcacat
     8581 ttgaaagaat atccgttatc gttttaggag cggatcatcc ggtttttact aaatcttctt
     8641 tggtacaaat cgcaggaaga gccgatcgta aagggcctta tacgaacagt caagtatact
     8701 ttttctatga agaaaaaact gcagctattc gaaaagcttg tcaggaaatc aaagaaatga
     8761 atgaagaagg gaagaagatg ctgtgaggtg cagttgctgc agtaaagata tcgtccaaaa
     8821 tttaacattc agcgagatta ttggtgtttc gaaatacaga ttacctcaga cttgttcagt
     8881 ttgtcgcgca caatttcatt tattggaaac aagaggctgt tctggctgtc aaaaaccaat
     8941 ccatttcaat ctagagagta cgaaaaagaa agtaaagtct attcccgttt actgcagtga
     9001 ctgtcaagaa tggaagaaga aatatccgac ctatgatttt cagcaccgtg ccttttttgt
     9061 gtacgatgaa aatatgaagg cctggctcaa tcaatacaag tttatgggag atatccgact
     9121 agcaggcacc tttgcatata aatggacgca gataaaaaaa gaatacccga catacatcta
     9181 ttgtccaata cctttatctg aaaaaaggcg aacagaaaga ggattcaatc aagtaagcga
     9241 gatgttgaaa gcagcaagaa ttccttttca gatgctactc aaaagagaga agcatctgct
     9301 ggctcaagca aaaaacacgc gaaaggaaag attggagatg cctcaacctt ttgaacttgc
     9361 agtcaccttt tctaagatac aaaataaaaa aatattgatt attgatgatg tctatacaac
     9421 aggacagact cttttccacg cagcagattg tttgcaggtc gcacagccga aaatcatccg
     9481 aaccatttct ttagcaagat gaattagatg tggaaatttg atagcgattt aatttgcaaa
     9541 taacctagag ttcgatataa tagaattaag aagagggaaa gagtggtcct tctccttctt
     9601 gattgtggta gacgaaaggg gtaattttta tgtttagata taatgtacgc ggcgaaaata
     9661 tcgaagtaac tgaagcgatt cgcgactacg ttgagaaaaa agtaggcaaa ctagaacgct
     9721 atttcagtga cgcacccgat gcaacggcgc atgtgaactt aaaagtttat acagaaaaaa
     9781 cagcaaaagt ggaagtaacg atcccattac cttatcttgt attacgtgcc gaagaaactt
     9841 ctccagattt atacgcaagt atcgatttgg ttgttgacaa attggaacgc caaatccgca
     9901 aattcaaaac aaaaattaat cgtaaatccc gtgaaacggg catgaatact gcagatgcta
     9961 ctgctttatt caatgaagag gacgaaaacg aaaatgattc tgaattagat atcgtacgta
    10021 cgaaacgcct ttcattgaaa ccaatggata gtgaagaagc agtcttacaa atgaacatgc
    10081 tgggacataa cttctttatt tttgaagatg cagaaacaaa tggtacaagt atcgtttacc
    10141 gccgtaaaga tggaaaatac ggactgattg aaacagactg atcagcctta cttaaataac
    10201 aacgaaaact tgcagcagct actgacagct gccgcaagtt ttt
//
LOCUS       DAYNVV010000084        10086 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.087, whole genome shotgun sequence.
ACCESSION   DAYNVV010000084 DAYNVV010000000
VERSION     DAYNVV010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10086
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.087"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..722)
                     /locus_tag="ACGXWR_002549"
     CDS             complement(<1..722)
                     /locus_tag="ACGXWR_002549"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFK0804034.1"
                     /translation="MTYKNIVFDLDDTLYDHQLPFKRSVEKCFPTIDIQQIDNIYKRF
                     RCWSDVAFPKYTKKLISIEQLRIFRCQKTMEEFGIDSISRTEALDFQADYEYELDQIT
                     MIPEIHQLLLALHKNRIPIGILTNGPVDLQSRKLQNIGAYQYFEKQNIIISQSTHGGA
                     AENSYEGNVKNLQSYQNVQLSKRAIEILKEEIELNHQHIRFNPDYKDNGWIFTSKSRH
                     KPGMATVFLTNFIRCRTSFRML"
     gene            complement(727..1494)
                     /locus_tag="ACGXWR_002550"
     CDS             complement(727..1494)
                     /locus_tag="ACGXWR_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFK0804035.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
     gene            1983..2408
                     /gene="lacA"
                     /locus_tag="ACGXWR_002551"
     CDS             1983..2408
                     /gene="lacA"
                     /locus_tag="ACGXWR_002551"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HFK0804036.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            2425..2940
                     /gene="lacB"
                     /locus_tag="ACGXWR_002552"
     CDS             2425..2940
                     /gene="lacB"
                     /locus_tag="ACGXWR_002552"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HFK0804037.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            2951..3883
                     /gene="lacC"
                     /locus_tag="ACGXWR_002553"
     CDS             2951..3883
                     /gene="lacC"
                     /locus_tag="ACGXWR_002553"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HFK0804038.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTISHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            3886..4866
                     /gene="lacD"
                     /locus_tag="ACGXWR_002554"
     CDS             3886..4866
                     /gene="lacD"
                     /locus_tag="ACGXWR_002554"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFK0804039.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDPRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            4894..5211
                     /locus_tag="ACGXWR_002555"
     CDS             4894..5211
                     /locus_tag="ACGXWR_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFK0804040.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            5211..6917
                     /locus_tag="ACGXWR_002556"
     CDS             5211..6917
                     /locus_tag="ACGXWR_002556"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HFK0804041.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTLLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVVSNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            7059..8465
                     /gene="lacG"
                     /locus_tag="ACGXWR_002557"
     CDS             7059..8465
                     /gene="lacG"
                     /locus_tag="ACGXWR_002557"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFK0804042.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRLKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            8488..8761
                     /locus_tag="ACGXWR_002558"
                     /pseudo
     CDS             8488..8761
                     /locus_tag="ACGXWR_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209209.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
     gene            8782..9681
                     /locus_tag="ACGXWR_002559"
     CDS             8782..9681
                     /locus_tag="ACGXWR_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFK0804043.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDEDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNSSLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDQL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
BASE COUNT         3181 a         1698 c         2018 g         3189 t
ORIGIN      
        1 aatagcatac ggaaagaagt tctgcacctt ataaaatttg tcaaaaaaac tgttgccatt
       61 ccaggtttat gacgactttt ggaagtaaaa atccatccat tatctttata atcaggattg
      121 aatcttatat gttggtgatt taactcaatt tcctctttaa gaatttctat agccctttta
      181 gataattgga cattttggta actttgtaag ttttttacat taccttcata gctattttct
      241 gcagctcctc cgtgagtgga ctgactaatg atgatatttt gcttttcaaa atattgatag
      301 gcaccaatat tttggagttt tcgactctgt aagtcaacag ggccattagt tagaatacct
      361 attgggatgc ggtttttatg tagagccagc agtagttgat gtatctcagg aatcatcgta
      421 atctgatcga gttcatattc atagtcagct tggaagtcta gagcttctgt cctagaaata
      481 ctatcgatgc caaattcttc catagtcttc tgacagcgaa aaattctaag ctgctcaata
      541 ctgatgagtt ttttcgtgta tttaggaaaa gcaacatcag accaacatct gaaacgtttg
      601 taaatgttat ctatttgttg gatatcaatc gttggaaaac atttctcaac gctacgttta
      661 aaggggagtt gatggtcata aagagtgtca tcaaggtcaa aaacaatatt tttataagtc
      721 ataattctag tccgctttta aaatagtagt gtactggcta aattcctcta agtgttgagg
      781 gctaatctgg ttatctgtaa tgatggtatc gagttgatct agattataga agttaaagaa
      841 atcgtatcga tcgaatttag tactgtctac taataagaat ttttctacag cattgtttag
      901 ggcaagttgt tgaatcacac cttccttgtc actatatgta gcaatagaat tatgggtaac
      961 agcatttgca ctaacaaaag ctttggcaaa tctaattgct tttaaatttg tcgaagccat
     1021 tgaacctaca aaagctccag ttatttctct atattcaccg ccaagaagca ataaatcaat
     1081 ggtttcgcta tcatttagaa tcaagaacac agggagacta tttgtaatga cacgaatttt
     1141 ataaccttta cgacctttca attctaatgc cagttgttca agtgtagttc cgggtccaat
     1201 aaaaatagta tcgccatctt tgattaaaga gcaggctttt ttagcaatgt caattttttc
     1261 ttttgtattt agacttttct tctcgatatg tgtcttttca agtggctttt tagaggaaag
     1321 taattgtgca ccaccatgag tacgtgttaa aagtccatca gcttctagag catcaaggtc
     1381 tctacgggct gtcatatcgg aaatatctag ttcatctatt atttctttta tggttatggt
     1441 cccatcaatc tttaacatat ctaaaatttt ttctaatcgt cgttttttgt tcatatgaag
     1501 acccttcttt cataaagtaa tttttttcca aagataattc tcttttaatt gtatcataaa
     1561 agacaatatt ttcaaggtaa aacaaacaat ttcaaacaaa aacaaatgtt agatgatgaa
     1621 ataagaacag tggattgacg tatattagct taggtcagat tttgtataag acgaaaataa
     1681 agtaggacct cttaatcagt aagttataga aagtaaaaga cttttgtaat acttgaatag
     1741 atatttcacg tccattttgt gatggattaa atgaacaaaa atgaacaata atttaacggt
     1801 gttatctatt ttttaagaaa acaaataaaa aaaacaaaaa ataaacaaaa aagtgttgct
     1861 ttttgtttga atgattgata ttatataaac aaagaaatga tgaaaacgtt ttttcgaaca
     1921 ttttgcaaaa tgttttctac ttctacgtag catttctttc taaaatttag gaggtggtca
     1981 aaatggctat tgttgttggt gcagatctca aaggtacgag attaaaagat gttgtgaaaa
     2041 attttcttgt agaagaaggt tttgaggtaa ttgatgtgac taaggacgga caagattttg
     2101 ttgatgttac cttggcagtt gcctctgaag taaataaaga tgagcaaaac ttaggtattg
     2161 taattgatgc ttatggagct ggtccattca tggtagcaac taaaattaaa ggtatggttg
     2221 cagcagaagt ttcagatgaa cgctcagctt atatgacacg tggacataac aattcacgaa
     2281 tgattacggt tggcgctgaa atcgtcggtg atgagcttgc taaaaacatc gctaaaggtt
     2341 tcgtcaatgg taaatatgat ggcggacgtc atcaaatccg agtagatatg cttaacaaaa
     2401 tgtgttaaga aaaggagtta aggaatgaga atcgcaattg gatgtgacca cattgtcaca
     2461 gatgaaaaaa tggcagtatc agaattcttg aaatcaaaag gacatgaggt ccttgatttc
     2521 gggacatatg accacgcacg tactcactac cctatctatg gtaaaaaagt cggtgaagca
     2581 gtagtaagtg gtcaagcaga cttgggagta tgtatctgtg gtacaggtgt cggcattaac
     2641 aatgcagtca ataaagttcc aggtgttcgc tcagcgttgg ttcgtgatat gacatcagct
     2701 atatatgcaa aagaagagtt aaatgcgaat gttatcggtt tcggtggaaa gattactggt
     2761 ggtcttctta tgaatgacat cattgaagct ttcattgaag ctgagtacaa accaacagaa
     2821 gaaaataaaa aattgattgc aaaaatcgaa cacgttgaaa cacataatgc acatcaagca
     2881 gatgaagatt tctttacaga attccttgaa agatgggacc gtggtgacta ccacgattaa
     2941 ggtataacaa atgattctga cagtcacact aaatccttca gtagacatct cttatcctct
     3001 agaaacattg aaaattgata cagtgaatag ggtgaaagat gttagtaaga cagctggtgg
     3061 aaaaggctta aatgttacta gagtcttgta tgaatctggt gataaagtta ctgctacagg
     3121 tttcttaggt ggtaaaattg gtgaatttat tgaaagcgaa ttagaacaat ctcctgttag
     3181 tccagctttt tataaaatct caggaaacac tagaaactgt attgctatct tacacgaggg
     3241 taaccaaaca gaaattttgg aacaaggacc aacaatttct catgaagaag cagaaggctt
     3301 tcttgaccac tatagcaatc ttattaaaca atcagaagtt gtgacaattt caggaagttt
     3361 accttcagga cttcccaacg attattatga aaaacttatc caacttgctt cggatgaagg
     3421 agtagcagtc gttttggatt gttcaggtgc acctcttgaa acagttctaa aatcgtcggc
     3481 taaacctact gccatcaaac ctaataatga ggaactttca cagttgcttg gaaaagaagt
     3541 aacaaaagat attgaagaac tcaaagacgt tcttaaagag tcacttttta gtggtatcga
     3601 atggatagtg gtctcattag gtcgaaacgg tgcctttgca aaacatggtg atgttttcta
     3661 taaggtagat attcctgata tcccagttgt taatccagtc ggatcagggg actcaacggt
     3721 agctggtatt gcatcagctt taaatagtaa aaaaagtgac gctgacttat taaaacatgc
     3781 gatgacattg ggtatgttaa atgctcaaga aacaatgaca gggcatgtga atatgactaa
     3841 ttacgaaaca ctaaactcac aaattggagt aaaagaggta taaaaatggt acttacagaa
     3901 cagaaacgca aatctttgga aaaaatttca gataaaaacg gtgttatctc agctttggca
     3961 tttgaccaac gtggtgcttt gaaacgtttg atggcacagt atcaagatac agaaccaact
     4021 gtagctcaaa tggaagaact aaaggttttg gttgctgatg aacttacaaa atacgcttct
     4081 tcaatgttgc ttgaccctga atatggactt ccagcaacaa aagcattgga taaagaagca
     4141 ggtcttcttc ttgcctatga aaaaacaggt tatgatacat caagtacaaa acgtttgcct
     4201 gactgcttgg atgtttggtc tgcaaaacgt atcaaagagc aaggcgctga tgccgttaag
     4261 ttcttgcttt actatgatgt agacagctca gatgaactta accaacaaaa acaagcttat
     4321 attgaacgtg ttggttctga atgtgtcgct gaagatattc ctttcttctt ggaaatcctt
     4381 gcttatgatg aagaaatctc agatgcaggt tctgttgaat atgcaaaagt gaaacctcgc
     4441 aaagtcattg aagcgatgaa agttttctct gatccacgct ttaacattga tgttcttaaa
     4501 gtagaagtac cagttaacgt taaatatgtc gaaggttttg ctgatggtga agtggtttac
     4561 agtaaagctg aagctgctga cttctttaaa gcacaagaag aagcgactaa ccttccatac
     4621 atctacctaa gtgcaggtgt atctgctaaa ttgttccaag aaacattgca atttgctcac
     4681 gactcaggtg ccaagtttaa tggtgtgctt tgtggacgtg ctacttgggc aggatctgta
     4741 gaaccttaca tcaaagaagg tgaaaaagca gcacgtgaat ggttgcgtac tactggattc
     4801 gaaaatattg atgaacttaa caaagttctt gttaaaacag ctagtccatg gactgataaa
     4861 gtatagtaaa aacataaaac ggaggatatt gttatgaaca gagaagagat gactctctta
     4921 gggtttgaaa ttgttgctta tgctggagat gctcgctcta aacttttaga agcgcttaaa
     4981 gcggctgaaa atggtgattt cgctaaggca gatagtcttg tagtagaagc aggaagctgt
     5041 attgcagagg ctcacaattc tcagacagct atgttggctc gagaagcttc tggggaggaa
     5101 cttccataca gcgttaccat gatgcatggt caggaccact taatgactac tgtcttatta
     5161 aaagatgtga ttcatcacct catcgaactt tataaaagag gagcaaaata atgcataaac
     5221 tcattgaact tattgagaaa gggaaaccgt tctttgagaa aatctctcga aacatctatc
     5281 ttcgtgctat tcgtgatgga tttatcgctg gtatgccagt catccttttc tcatctatct
     5341 ttatccttat tgcctatgtc ccaaatgctt ggggattcca ctggtcaaaa gacattgaga
     5401 ccttcttgat gactccttat agctattcga tgggtatcct agcattcttt gttggtggta
     5461 ctaccgctaa agctttgacg gactcaatga accgtgacct acctgcgacc aatcagatta
     5521 acttcttatc tacgatgcta gcgtctatgg tagggttcct tttgatggca gctgagcctg
     5581 caaaagaagg aggcttcttg acagccttca cgggaacaaa aggtcttttg acagcattta
     5641 ttgcagcctt tgtgacagtt aatgtttaca aggtctgtgt gaaaaataat gttactattc
     5701 gtatgcctga agaggttcca ccaaatatct ctcaagtatt taaagacttg attccattca
     5761 ctgtagcggt tgttctcctt tatggatttg aactcattgt taagggaact cttggtgtaa
     5821 ccgttgcaga atcaatcggt acccttcttg ctcctctctt ctcagctgca gatggttacc
     5881 ttggaattac acttatcttt ggtgcttatg ccttcttctg gtttgttggt atccacggtc
     5941 cttcaattgt cgaaccagca atcgctgcta tcacttatgc caatatcgat gccaacttgc
     6001 atcttatcca agctggacaa catgcagata aagttatcac ttctggtact caaatgttta
     6061 ttgttaccat gggtggaaca ggagctacat tgattgttcc attcttgttc atgtggattt
     6121 gtaaatcaga acgtaaccgt gccatcggac gtgcctcagt tgttccaaca ttctttgggg
     6181 ttaatgagcc aatcttattt ggtgcaccaa tcgtattgaa tccgattttc tttgtaccgt
     6241 tcattttcgc tccgattgtc aacgtttgga tctttaaatt ctttgttgac acattgaaca
     6301 tgaactcatt ctctgccaac cttccatggg ttactcctgg tccgttggga attgtactcg
     6361 gtactaactt ccaagttcta tcatttatct tagccggact cttggtagtt gttgatacta
     6421 tcatttatta cccatttgtt aaggtatacg atgaacaaat tcttgaagaa gaacgttctg
     6481 gtaaaacaaa cgatgctctt aaagaaaaag tagctgcaaa cttcaatact gctaaagcag
     6541 atgccgttct tggaaaagca ggcgttgcta aagaagatgt agcagcaaac aataatatca
     6601 caaaagaaac taatgtcctt gttctttgtg caggtggagg tacaagtggc ttgcttgcca
     6661 atgccttgaa caaagcagca gcagaataca atgttccagt caaagcggca gcgggtagtt
     6721 acggtgctca ccgtgaaatg ttgccagagt ttgacttggt tatcttggct ccgcaggtcg
     6781 tttcaaactt cgatgatatg aaggctgaaa cggataaatt gggcattaaa cttgcaaaaa
     6841 ctgaaggagc tcaatatatc aaattgacac gtgatggaca aggtgctctt gcatttgttc
     6901 aacaacagtt tgattaataa atttgtaaaa gttatttgag acgagattat tctttcagtt
     6961 ccttataata ttgttaacca tatcattgca tttcatttcc ttggtttccg gaactcagaa
     7021 tatcgtctca aatgcttttt ttgaaaggat ttatagttat gactaaaaca cttcctaaag
     7081 attttatttt tggtggtgct acagctgctt atcaagcaga aggtgcgact cacacggatg
     7141 gtaaaggccc agttgcatgg gataagtatc ttgaagacaa ttattggtac acagcagagc
     7201 ctgcaagtga tttttaccat aaatatcctg ttgatttaga attagctgaa aaatatggcg
     7261 ttaatggtat tcgtatttca attgcctggt ctcgtatttt cccaactggc tatggcgaag
     7321 taaatgaaaa aggtgttgaa ttctaccata atctttttgc cgagtgccac aaacgtcatg
     7381 ttgagccatt cgtgactttg caccactttg acacaccaga agttcttcac tcagatggag
     7441 atttcttaaa ccgcgaaaat atagaacact ttgtagatta tgccgctttc tgttttgaag
     7501 agttcccaga agtaaactac tggacaactt tcaatgaaat tggcccaatt ggagatggtc
     7561 aatacttggt tggtaaattc cctccaggca ttcaatatga tcttgccaaa gtcttccaat
     7621 cacaccacaa tatgatggtt tctcatgcac gtgctgtgaa attgtataaa gataaaggtt
     7681 ataaaggcga aattggtgta gtacatgcgt tgccaaccaa atacccttat gatccagaaa
     7741 atccagcaga tgttcgtgcc gctgagttag aagatatcat ccataacaaa tttatcttgg
     7801 atgcaaccta ccttggacac tattcagata aaacgatgga aggggtcaac cacatcctag
     7861 ctgaaaatgg tggagaactt gatcttcgtg atgaagactt ccaagcactt gaagcagcta
     7921 aagatttgaa cgatttcctt ggtatcaact actacatgag tgattggatg caagcctttg
     7981 atggtgagac tgaaatcatt cacaatggta agggtgaaaa aggaagttct aagtaccaga
     8041 ttaaaggtgt tggtcgccga atcgcaccag attatgtgcc tagaacggat tgggactgga
     8101 ttatttatcc tgaaggcttg tatgaccaaa tcatgcgatt gaaaaatgat tatccaaact
     8161 acaagaagat ttacatcact gaaaacggtc ttggatacaa agatgagttt gtagataata
     8221 ccgtttatga tgatggtcgt attgattacg tgaagaaaca cttggaagtt ttatcagacg
     8281 caattgcgga tggtgcaaat gttaaaggtt acttcatctg gtcacttatg gatgtcttct
     8341 catggtcaaa cggatacgaa aaacgttatg gactattcta tgtagacttt gacacgcaag
     8401 aacgctatcc taagaaatca gctcattggt ataagaaagt agcagaaact caagtgatag
     8461 agtaatatta cttgaaaatg taaaaaattg ttatccgata ctttagaaaa agtacaacac
     8521 ttatttagac caggctttga aaaggtatat attgttagtt tcgaagattg tcctatgatt
     8581 cctgagcttg aagctaccct cgttgctaaa atgtggtaaa tggtatgttt taactggaaa
     8641 agagtggatt tgccattctg atttagagtt atcagcattt gaatgggaat ttttacaatc
     8701 actcgatgta gaaatacgtg agactattca cttcgaggta aattatttgc ctttccaata
     8761 ataaaaagaa aggaattagt tgtgactatc gaattaaaaa acgagtatct tactgttcag
     8821 tttaaaacac ttggtggtca actgacttcg attaaagacg aggatgggat agagtatctc
     8881 tggcaagctg atccaaatta ttggaatgga caggcgccta ttctatttcc tatctgtggt
     8941 agtttacgaa atgattgggc tatttataga cctcaagaaa gacctttttt tacaggtctt
     9001 attcgtagac atggttttgt tcgaaaagaa gaatttattc tggaagaagt caatgataat
     9061 agcgtgacct ttagtattaa accaaatgct gagatgcttg ataattacct atatcagttt
     9121 gaactgagag ttgtttatac cttgaatggt aaatcaatta gaaccgaatt tcaggtaacg
     9181 aacttggaaa tggaaaaaac aatgccttac tttattggag cccatccagc attcaatagt
     9241 tctttagtag aaggtgaaaa ctatgaggat tattatattg aatttagtga ggttgagtct
     9301 tgctcgatac caaagagttt tcctgagaca ggattattag atttgcaaga tcggacacct
     9361 tttttggaaa atcaaaaaat tctcgatttg gactactcac ttttttccca tgatgccatt
     9421 acacttgacc agctcaagtc tcgtagcgta acgcttcggt caaggaagtc tggtaaaggt
     9481 cttcgagtag attttgatga ttttccgaac ttgattctgt ggtctacaac taataaaagt
     9541 ccattcattg ctttggaacc ttggagtggt ctctccactt cacttgaaga aggtaatttc
     9601 ttagaagata aaagacaggt aacgaaaatt tcacctcaag aaacttctag aaaaatctat
     9661 gatattacta tccttaatta aaatttgtta ttatttgagt cttcaataag atttgaatac
     9721 tcttaccttg tgatgataga ttggtcttct ccgtgccagt cttacatcgc aaggttttta
     9781 agttttttgt gggtctatgt caactgtagt gggtgacgaa aagctaatat ctaaagacag
     9841 tctggtagta aaaaataaga ttatttacta cttcttgatt taaaataata gtggagccat
     9901 taatttgtgg caaatttaat ttaatatttt gcctcaaatt agccacactt tttatagaac
     9961 taagaggaaa aatgaaattt tcttcctatt aatatagttg tttgaaatct taaatatagc
    10021 gttttggaat ggcaacagtt tttttgacaa attttataag gtgcagaact tctttccgta
    10081 tgctat
//
LOCUS       DAYNVV010000085         9791 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.088, whole genome shotgun sequence.
ACCESSION   DAYNVV010000085 DAYNVV010000000
VERSION     DAYNVV010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.088"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(173..694)
                     /locus_tag="ACGXWR_002560"
     CDS             complement(173..694)
                     /locus_tag="ACGXWR_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HFK0804044.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(697..1539)
                     /locus_tag="ACGXWR_002561"
     CDS             complement(697..1539)
                     /locus_tag="ACGXWR_002561"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HFK0804045.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(1532..2257)
                     /locus_tag="ACGXWR_002562"
     CDS             complement(1532..2257)
                     /locus_tag="ACGXWR_002562"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HFK0804046.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            2433..2729
                     /locus_tag="ACGXWR_002563"
     CDS             2433..2729
                     /locus_tag="ACGXWR_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804047.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     regulatory      2985..3159
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            3297..4889
                     /locus_tag="ACGXWR_002564"
     CDS             3297..4889
                     /locus_tag="ACGXWR_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFK0804048.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            4902..5642
                     /locus_tag="ACGXWR_002565"
     CDS             4902..5642
                     /locus_tag="ACGXWR_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFK0804049.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            5810..7159
                     /locus_tag="ACGXWR_002566"
     CDS             5810..7159
                     /locus_tag="ACGXWR_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFK0804050.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(7287..7877)
                     /locus_tag="ACGXWR_002567"
     CDS             complement(7287..7877)
                     /locus_tag="ACGXWR_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFK0804051.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            8024..9376
                     /gene="brnQ"
                     /locus_tag="ACGXWR_002568"
     CDS             8024..9376
                     /gene="brnQ"
                     /locus_tag="ACGXWR_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFK0804052.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         2804 a         1865 c         1946 g         3176 t
ORIGIN      
        1 ttttatgttt ctccactaat cgaaatttag atagacatct agaaatcgca attccaaaaa
       61 attctgtgta ttggatacgc atcttttctt attttttctt atttcttcca tatgggtgtt
      121 tatctcagag atgatagaat agtttctagg ataaaaagta gcagctacga tgttatcctt
      181 cgtagaggat tcctgcttca gctagttttt gtttgatgtt tttcagcata tgcttttctg
      241 ggtagcggat cgtatgcaga tggatgccgc ctgttaattc ggataacaaa gtagcattac
      301 ttttttgata acgtctcata aaggaatcga tatcttgtgg cgttttgatg tgcaaagttc
      361 ctgctaactc accgtaaagg ggatgttcca caattacatc aatgatttca ccaccatttt
      421 caacgattag tctcagttct tcttctgttt gatcttttcc atgctggaca gcgattttac
      481 tgatgtgccc agtattggtt tcttctgttt cgaggatata acctcttgct gttgccacga
      541 tacttttacc tgcagctcgt agtaaagcaa tatcgcctac aatgatctga cggctgactc
      601 caaaagtttt cgcaaacttg ctagcactca ctggtttttc tgtatttgcc aaggtttgca
      661 tgatttgttt tcgccgtgtc tctccttcga tcacacttat tcctccttca ttttgttttg
      721 gtattcgcgc gagtgtttca tcaaatcaac atacgtgtct gttattgttt ccttatatcc
      781 cttatttttc agcagactaa caactttatc caatacttgc tgctctcttt ttgcatcata
      841 aactgcttgg ttttcttctt ttttcacttg tcctatttta gttaccgtat ccattctttt
      901 ttctaataaa gcaaccaact ctcgatcgat catatcgatc ttatgacgta atgtttcaag
      961 agactcttct gttagttctt cctctactgt cttgatgata cgagcaggat ttcctgcaat
     1021 cactacattg tcgggaaaag atttggtcac aaccgaacct gcgccgacta ctacgttgtc
     1081 ccctagagtg acacccggcg tgacgataac tcctccgcct aaccaaacat tattaccgat
     1141 tttaatgggt tttgcgtact ccagaccgct gttacgtttc actggatgta gtggatgcgt
     1201 cgccgtgtaa agctggacat tcggagcgaa catgcagtta tcaccgattt caatcgtgct
     1261 gacatctaaa aatgtacaat tgaaatttgc ataaaaattc tccccaacaa atatattata
     1321 tccgtaatca aaattgataa ctggctccat atagattttt ttccctgtac ggccaaaagt
     1381 ctctttcaac aattgggatc gcagttccgc tgattctgct tggttgatga tttggctttg
     1441 acttcttgca aacatacggt cggcaaccag ctcaggatca ttggcaaaat aaagctcgcc
     1501 tgcaatcatt ttttcttttt cggttttgaa ttcagtcata atctgctcct aattcttgta
     1561 tttttttgaa aacaaccgct ccgtcttctt gaataaacgt ataaggctcc gctaaataaa
     1621 caggcgtttg attgattact aagattttgg ctgacggctg gcgaaactgt accagatcac
     1681 aaaacggatg aacttgaaaa ctcgttccaa caatgacgat cagctctgct tggctgacgg
     1741 cataagccgc ctgctccatg actccatctt gaaacccttc accatataac acgatgtctg
     1801 ggcgtatttg tcctccgcat gcttgatgtt tgtcgctgtg aagatattct ttccagtcta
     1861 ccgtttgttg acattttcga caatgacatt gatacagact cccatgaaaa ttgacgagtt
     1921 gcgggctttt agcctttgcg tgcaaaccgt cgatgttttg ggaaacaacc caaacatttt
     1981 tttctttcgc tagatgtgct atttccaaat gaatgatatt gggttttgct tcaggatgat
     2041 aaatcttttt gacaaattga tagaatttat ccggttcatt caccattgct tgatgactca
     2101 gcaagtattc cggctgctcc atcccgtggt agattcctga caaagatcga tagtctggca
     2161 ctccagaagg tgtggatacc cctgcaccgg tcaaaaatgt aatttgctga taagctaata
     2221 tctcttttgc tgcttcgtct actgttaatt gtttcatgtt ttgtcacctc actttccatt
     2281 atagcccata ctcgaacaaa tttattgttg aaaagtcaga aaaatgggaa taaaaaagtg
     2341 ttatgggcat ttgagcaatt tatcacaatg ttcactgaca aaagaatgaa aacgtgttac
     2401 aatactgctg tataaaagtg aggtgaatcg atatgttacc attctttatt tattggggcg
     2461 ttattctggc ttgtatcgcc tggttagcgt taagcgttta tttctctgtt ttttatcttg
     2521 tacgcaaaga aaatggaaat ctttgggctt ttgctttatt caacgtgatt gccgcaattg
     2581 ttttagccat tacattagcc gtatatcgaa catggggctg gggaatcacc caatactcaa
     2641 gtttgattta tctaatatta gccatttatg gcgtcgttgt tcttttgcaa gcgatcctag
     2701 gacgtgagcc aaagaaagcg gcagcttaaa tgatcgagat ggaactggac acaggaaatt
     2761 ttctgttcta gttctttttt tattgtatta catacatttt tgtgtataat tatactatcg
     2821 tttgcaatgg atagatgatt cacattttga ttgttttttc ggtaaaagta aagatttcta
     2881 tatttatcag tattttttca aaaaccagca gttatagatt gacaaagcct ctcgagtatc
     2941 gtaaactttt tttgtataaa taactgaata cgagatgcct caatcaatga ggtagaggtc
     3001 gcgagaatca ttaaccctgt ggagtgaagc aaacatggag aagcaggaat agggaggatc
     3061 gccgaaatgt gcactttttt gcttggagtg tatgttggga cgcaagttaa gagcttgcgg
     3121 actgtcttag cagtgatgct aagttgcgct atgttttgtg agaggtttat caccttatgg
     3181 aattttagcg gcctttttat atctataaat cggtcgcttt ttattttttc agataaagct
     3241 ttaccgcatt tcatctagac cgctcgtgta tcatataatc agaaagggag aaaaaaatga
     3301 aaaaaaatat ggtttcagtt gccgtactat ttgcttttgt cttctcacta ttcagtgtgg
     3361 gatctctggc aaatgcagat gaaaaaacac cgagcgatga gtttcgcgta ggtatggagg
     3421 ctgggtatgc acccttcaac tggtctcaac aaacagatga gaataatgcc ttgccaattc
     3481 aaggccaaaa tagttacgcc ggcggttatg atgttcaaat cgctaaaaaa gtagcagatg
     3541 gtttagggaa aaaattagtc atcgtccaaa cgaaatggga tggtctggct cctgcccttc
     3601 aatcaggcaa gatcgacgcg atcatcgccg gaatgagccc tactgctgaa cgacgaaaag
     3661 aaattgattt taccgatcct tattacgaat cacaattagt agtagtagtt caaaaagata
     3721 gcaaatatgc aaaagcaaaa agtttagcag atctttctgg agcaaagatc actgctcagt
     3781 taaatacatt ccactatact gtgatcgatc agataccaga tgtgcagaaa caacaagcaa
     3841 tggataattt ctcagcaatg agaacagctt tagcttctgg aatgatcgat ggttatgtca
     3901 gcgaacgtcc ggaaggtgta acggcaacta gtgtgaacaa agacttggaa atgcttgaat
     3961 tcagcggtgc agatggcttc cagacaaacc cggaagatgt tcagatttct gttggtatgc
     4021 gtaaaggcga cccggatatc caaaaagtaa accagattct ttctggcatc tctaacgatg
     4081 aacgaaccaa aattatggac caagcagtca aagatcagcc tgctgcaact gatagtgaag
     4141 aaaaacctgg catcatttct gatttcacta cgatttggaa acaatacggc aatatgttct
     4201 tacgaggtgc tggacttacc ttgttcatcg cattgatcgg gacagttgtc ggtactacac
     4261 ttggattact gattggtgtc ttccgttcgg tacctgaatc aggaaatgca ctgactcgct
     4321 tcttccaaaa aatcggaaat gcacttcttt ctatctatgt cgaagtattc cgcggaacac
     4381 cgatgatggt acaagcaatg gtcatcttct acggtctggc actcgctttt ggcatttcat
     4441 tgaaccgaac gattgccgct ttgtttattg tctctctcaa tactggagct tacatgacag
     4501 agatcgttcg tggggggatt tttgcagtag atgaagggca gttcgaagct gcgcaagcca
     4561 ttggtatgac ccatggccaa acgatgagaa aagttgttat tccacaagtt ttacggaata
     4621 tcttgccagc aacaggaaat gagtttgtta tcaatatcaa agatacagca gttttaagtg
     4681 taatcggcgt agctgatttg ttcttccaag gaaactctgc ttccggtgcg aatttccaat
     4741 tcttccaaac atttacgatc gtcgggatca tctacttagt catgaccttt acgatcacca
     4801 gaatcctgcg ggcggtagaa aagaaaatcg atggtccttc agcttatacc aagcttgaag
     4861 aaatcgacaa ttcaaatttg caggaataag gaggaagaat catgaatgaa aaaattattg
     4921 aaatcaaaca tctaagaaaa agcttcggtg aaaatgaagt attgaaagat atcagcgtaa
     4981 cagtcaataa aggtgaagtt gtgacgatca tcggttcttc cggttctggt aaatctactt
     5041 tcttgcgctg tatcaattta ctggaaaaac caacaggcgg cgagatcatt tataatggag
     5101 aaaatgtatt agctcctaaa tataatttac ctaaatatcg aacgaatcta ggtatggttt
     5161 tccaatcctt caacctgttc aacaatatga atgtcttgga aaactgtatg tctggtcaaa
     5221 caactgtcct gaaacgagat aaagaaactg ccaaaaaagt agcaatcgaa aatctggaaa
     5281 aagttggtat ggatcgttat atcgaagcca aaccagcaca attatctggt ggacagaaac
     5341 agcgtgtcgc aattgctcgg gcattatcaa tgaatccaga tgtattgcta ttcgacgaac
     5401 ctacttcggc gttagaccct gaaatggttg gcgaagtgct taatacgatc aaagacttag
     5461 cacatactgg cttgacaatg cttatcgtga cgcatgagat ggaatttgca aaagatgtat
     5521 ctgaccgtgt catttttatg gataaaggtg tgattgcaga agaaggtaca ccagaagata
     5581 tctttgtcca tccgaaagaa gaacgtacaa aagaattcct ttcacgtatt ttaaatgctt
     5641 aggatcaata gctgattggg acaaagagct gcggtgttta ccgcagttct tttttatgaa
     5701 ttactcataa aaggtaaatt tctgaaaatt ttggaatctt agttgtgttt ttcagaaaac
     5761 tctcttaata tggaagtaat taaacttttt tagttaggat gatttaaaaa tgaatgaaga
     5821 gcaagaactg cagcgtggac tgaaaaatag acatgtccaa ctgatttcta ttggcggagc
     5881 gattggaacg gggttgtttt taggttccgg aaagtctatc cagctagctg gcccttcgat
     5941 attgctcgcc tatcttatta ctggatgcat ctgttttttc attatgcgtg cgttaggcga
     6001 acttctgtta tcaaacacca ataaccattc ttttctggat tttgttgcag aatatcttgg
     6061 caaaaaagcg gctttcatca ctggctggac gtattggttc tgctgggtat cgattgcaat
     6121 ggccgattta acagccatcg gaatgtatgt acgctactgg gcgcctggtg ttcctcagtg
     6181 gcttcctgaa ctgattgcat taggtcttct tctttgcttg aatatggtgg ctgtctcatt
     6241 gtttggtgag ttagagtttt ggtttgcatt gatcaaagtt gtagcgatca ttgcctttat
     6301 cctcgtagga gcttatatga tcctcaccca ctatacgaca gatattggca cagccagtat
     6361 cacgaatcta tggtctcatg gcggattctt tccaactggt gcaaaaggat ttatcttagc
     6421 tttccaaatg gtaacctttg cttttgctgg gatagaatta gttggattag tcgctggaga
     6481 aacagaaaat cctgaaaaag tgttgccgga agctatcaat aatattccta tcaggatcat
     6541 cttattttac ttaggatctc tttttgtcat tatggcaatc tatccatgga acagcttgaa
     6601 tccagataac agtccatttg tagaagtatt ttcggaaatt gggatcacga ttgctgcttc
     6661 cttgatcaat ttagtcgtat taagtgcagc agcttctgcc tgcaacagtg caatatatag
     6721 tacaggacgt atgcttcgtt ctttagcgca agaaggcagt gcccctaaaa aattcaaaaa
     6781 gttaacaaca catcatgtgc cagggaatgc tttgacattt tctactatcg tcattttcat
     6841 ttctgttatc ttgaattacg tgatgcctag tgaagtattc acactagtaa gcagtattgc
     6901 cactacttgt ttcttgttta tctggagtat gcttgtctac acgcacatga aatatcgtaa
     6961 aagtatcctc ggcaaaaaag ctcattcatt taaaatgccg ttgtacccat ttagtaatta
     7021 tctggtattt ctttacatgg cctttgtgtg tgtcgtcttg ttcctaggaa aagatacgag
     7081 aatcgcttta ttactaacac ctgtgtggtt cttgcttcta ttactaatct atcatatgaa
     7141 atatgaacgt aagaagtaag aaagtagttg tgacagaagt ggtcagcttc gagaaataag
     7201 aaggaattta cgaaaattgc ttcttaaatt tttgtgaaat ttcggcttat ttcttggaga
     7261 taaaagcttc tgtcccagcc tcttttctat ttccccggaa acaaccgctg ataataggca
     7321 tctgcttttt tataggaaaa aatccaaata ccagatacaa aaaaacgtcc gaataacccg
     7381 atcaacggta caaaaaagac accggcaatc aagcataagt taatcatcat ggagataaga
     7441 cttcgacggt cctttgacaa aactctcacg acatgggaat ctggtttatt tgctttcatg
     7501 atttgcctca tcaagatacc aaaagaaaaa ctccacatcg tgtatactaa gacataagcc
     7561 atctcaggcc aaaaagcttc agggttacgc ccgacccaac tagtaacaga aggacataaa
     7621 gtcagccaaa agagcaaaaa gatattcgac cagaccactc ggtaattaat tcgttctgcc
     7681 atctgaaata tacgatgatg gttcacccag atcaccgcaa caaatataaa gctgatggta
     7741 taagctaata atgtatttcg gatgacccat aaagaatgaa agctagatgt attagggatc
     7801 ttgatctcta atacaataac tctcaaaaca atggctacca ctccatcagt aaatgcttct
     7861 aatctcgact ttgtcacgat gattcctcct cagatgattc agcgctttta ttttatcact
     7921 tacgttatta aataaccatc gttttatata gggaattttc tgaaaattgt tgcatatttt
     7981 tcgaaatttt gttactttta aaaaaaccgt aaaggagtta tgtatgacaa aaaaattatc
     8041 atttaaagac tatcttttta taggctccat gcttttcggt ctattttttg gtgctggaaa
     8101 tcttatcttt cccgttcatt tgggtcaaga agcaggcgct gctacctttt gggcgaatct
     8161 aggtttcttg gttaccggta tcggtcttcc cttcttaggg gtgattgcca ttggtgtatc
     8221 gaaaagctca ggtgtatatg aattagcaaa acggataaat caaacatatg cgatggtttt
     8281 taccatcttg ctttacttag ttatcggacc gttttttgct ttacctcgcc ttgcaaccac
     8341 atctttcgag attggtttag caccatttat cgatcctagc agacagacgc tatatctagc
     8401 aattttcagt attgtatttt ttgtgctggc ttggtggttt tcaagaaaac cgacaaagat
     8461 attagattat gttggaaagt tcctgaatcc tgcatttttg gttttattag gtgctttgct
     8521 tctccttgct tttttgaatc cactaggttc tgtaaatcaa gcgcctattc agccaaatta
     8581 tcaagagcat gcttttttca cagggtttac tcaaggatat aacacattag atgcgcttgc
     8641 tgctttagca tttgggatca tcattgtcac aacaatccaa aacatgggtg taacaaaacc
     8701 tgctgaaatc gctaaagaca cgatcaaatc tggtgcgatc agcattatat tgatgggaat
     8761 catttatact ttgctcgctt atttaggtgc tatgagctta ggtagctttg ctctaagtga
     8821 aaatggcggg atcacgctgg ctcagattgc tgatcattat ttaggtactt atggcagtat
     8881 cttattagca tttatcgtta tattagcttg cttgaagacc ggtattggtt tgattacagc
     8941 ttttgcagaa acattcacag atttgtttcc gcaaagaaat tacgcattct ttgttgcact
     9001 tgctagtatc cttccttgtt tagcggcaaa cgtaggcttg acgaatatca ttcaattttc
     9061 gttgcctgtt ttgatgttca tctatccatt agcaatgaca ctgattttac tagtgttagt
     9121 tggtcctttg tttaagcagc gtacggctgt ttatcgaatg actacttatt ttacattgat
     9181 tgcttcgatt tttgatgggt tgaacgcttg cccagaaact atcaaacaaa cacctattgt
     9241 tcaaaatctt ttatatgttg cggaaagcta cttgccgttt ttcaaattgg ggatggggtg
     9301 gatcgtacca gcagttatcg gttttgttat cggactgatt tggagtttcg ctaagaaaga
     9361 agaagtagca gattgataaa agaggttgtg aaagagacgt tcagccttga gcaataaaaa
     9421 gtaattttga aaaatggctt ctcacatttt tgcataaatt tgacttaata ccgagaaact
     9481 gacttttgaa caccgtttat tgagaggtcg tgaaaaagcc gcttagtttc aagtattaag
     9541 aaatattttg tgaaaatggc ttctcacatt tttgcataaa tttgacttaa taccgagaaa
     9601 ctggcttttg aacaccgttt attgagcgtc tataaactga cctgagtatt agagaaacaa
     9661 aacggcaaag tagctccata tactttgccg ttttgttttg aactaatacc gaagagaagc
     9721 tgatcaaaca acatttcttt tataatatag attttagaca tatatatgat ataaaaatag
     9781 ttttcgcaaa a
//
LOCUS       DAYNVV010000086         9571 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.089, whole genome shotgun sequence.
ACCESSION   DAYNVV010000086 DAYNVV010000000
VERSION     DAYNVV010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.089"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            130..951
                     /gene="racE"
                     /locus_tag="ACGXWR_002569"
     CDS             130..951
                     /gene="racE"
                     /locus_tag="ACGXWR_002569"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HFK0804053.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            954..2309
                     /gene="rph"
                     /locus_tag="ACGXWR_002570"
     CDS             954..2309
                     /gene="rph"
                     /locus_tag="ACGXWR_002570"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HFK0804054.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            2310..2828
                     /locus_tag="ACGXWR_002571"
     CDS             2310..2828
                     /locus_tag="ACGXWR_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFK0804055.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            2935..3435
                     /gene="cbpB"
                     /locus_tag="ACGXWR_002572"
     CDS             2935..3435
                     /gene="cbpB"
                     /locus_tag="ACGXWR_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HFK0804056.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(3715..4635)
                     /locus_tag="ACGXWR_002573"
     CDS             complement(3715..4635)
                     /locus_tag="ACGXWR_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HFK0804057.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            4761..5813
                     /locus_tag="ACGXWR_002574"
     CDS             4761..5813
                     /locus_tag="ACGXWR_002574"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HFK0804058.1"
                     /translation="MIKCGENNEGGKYMQIDWNNLGFSYIKTPWRFIAKWKDGQWEEG
                     ELTEDNYLTIHEGSPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLM
                     PMVPEKMFVDAVKQVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVF
                     CTPVGAYFKGGLKPTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCV
                     YLDPATHTKIEEVGAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIE
                     GDIFIDDLDQFAEAGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGI
                     QFGDIEAPEGWIEVVE"
     gene            complement(5923..6678)
                     /gene="fabI"
                     /locus_tag="ACGXWR_002575"
     CDS             complement(5923..6678)
                     /gene="fabI"
                     /locus_tag="ACGXWR_002575"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HFK0804059.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            6898..7338
                     /gene="fabZ"
                     /locus_tag="ACGXWR_002576"
     CDS             6898..7338
                     /gene="fabZ"
                     /locus_tag="ACGXWR_002576"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFK0804060.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(7453..8214)
                     /locus_tag="ACGXWR_002577"
     CDS             complement(7453..8214)
                     /locus_tag="ACGXWR_002577"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFK0804061.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            8403..9497
                     /locus_tag="ACGXWR_002578"
     CDS             8403..9497
                     /locus_tag="ACGXWR_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HFK0804062.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         3109 a         1679 c         2006 g         2777 t
ORIGIN      
        1 aagtcacaac cgcttttcct ctttccattc gaaaaaaaga gatttcgatt gttttaagca
       61 agtaagagca cttgaaaatt cacgctaaaa agtacacaat agggaggata gaatttattg
      121 aaaaaaagga tgatacgatt gacagataat cgccctatcg gatttattga ttcaggtgtc
      181 ggcggcttga ctgtagtaaa agaagccctg aaacaattac cgaatgaaaa tattttattt
      241 gtaggagaca cagcacgctg cccatatggc cctagacccg cggaacaggt aatccagtat
      301 acttgggaaa tgacggatta tctggtggag caaggaatca agatgctggt gatcgcctgc
      361 aataccgcaa ctgcggtggc tttagaagaa atcaaagctg ctctttctat tccagtcatc
      421 ggtgtgatcc ttcccggtac tagagcggca gtaaaaaaaa cacaaaataa acaagttggc
      481 attatcggta cgattggtac ggtaaaaagt caagcttatg aaaaagcact gaaagagaaa
      541 gtaccagaat tgactgtgac aagtcttgct tgtcccaaat ttgtttcagt tgtcgaaagt
      601 aatgaatacc attcatcggt ggcgaaaaaa attgtggcag aaacattagc tcctttaacc
      661 actaaaaaaa tcgatacatt gattttggga tgcacccatt atccattatt acgccccatc
      721 attcaaaatg taatgggaga aaatgttcaa ctgatcgatt ctggagcaga aacagtaggt
      781 gaagtatcta tgctgttaga ttatttcaat ttgagcaatt caccgcaaaa tggtcggaca
      841 ttatgccagt tttatacaac tggctctgcc aaacttttcg aggaaatagc tgaagactgg
      901 cttggaatcg gacacttaaa tgtagaacat atcgaattgg gaggaaaata aggatgcgtc
      961 atgacgggag aaaagcccaa gagcttcgca aactggagct tcaaacaaat gttttcaaat
     1021 atccagaagg atcggtagtg atccgttttg gtgatacaac agttatttgt tctgcaacaa
     1081 tagaaaattc tgttccccct tttttgagag aaacaggaac aggatgggtg acagcagaat
     1141 atagtatgct gcctcgagca acgagtacga gaaatcgtag agaaagcagc aaagggaaac
     1201 tttctggtag aacaatggaa atccagcgtc ttattggtcg ttccttgcgt gcagtagtag
     1261 acttggaaaa attaggagaa cgtagtatca tcgtagactg cgatgtgatc caagcggatg
     1321 gcggtactag aacagcaagt atcactgggg catttgtggc attgaaatta gccattgaaa
     1381 aacttttaag agaaaaagaa ttgtcagaag atccaataaa agaacatctt gctgcagtta
     1441 gcgtaggaat cttaccagat gggacttgcg tcacagattt ggattaccaa gaagattccg
     1501 cagcacttgt agacatgaat cttgtaatga cagaatctgg aaaattcgtg gagattcaag
     1561 gaactggaga agaagcaacg tttgatggtg aacagttgaa tgaaatgctc ttttttggaa
     1621 aaaacgcgat tgaagatttg atcaaagagc aaaaacatgc tttgctaaca gagtttgctc
     1681 aaaatgatga gcggatagaa gaaacaaaaa caatcatcat tgcgacaaga aatccaggaa
     1741 aagcagaaga gtttcgaaat atgttcaaag aagcgggata tcatgtaaaa acattacttg
     1801 actatcctga attgccagat gtggaagaaa ctggcagcac atttgaagaa aatgcccgat
     1861 taaaagcaga aacgattgca caattgcttg atcagccagt cttagcagat gattcaggtt
     1921 tgaaagtgga tgctttaggc ggtatgccag gaatctattc tgcacgtttt gcaggggaac
     1981 aaaaaagtga tgcggggaat aacgccaaat tattatatga attgacagat gtgccggatg
     2041 aaaaaagaac agcacaattc cattgtacgt tagtattcgc ggcacccaaa aaagacagcc
     2101 ttgtagtaga agcggaatgg cccggtcgag tagcccgtat accatctggc gaaaatggct
     2161 ttgggtatga tcctttattt atcccagaag gtaagaaaca aacagcagca gaattatcga
     2221 gcgaagaaaa aaacaagatc agtcatcggg ctcaagcaat gaaaaaattg agtgccgagt
     2281 ggaaacaatg gctggaagga gagagataga tgcggtattt agtagtaagt gataatcatg
     2341 gagacagaga tatcctcgtt gacttagtag atcgttatcg ttctgaagtg gatatctttt
     2401 tccattgtgg tgattcggaa ttagaagctt ctgacccatt atgggataca ttccaagtgg
     2461 ttcaaggtaa ttgtgattat ggaccaggat tcgaacagaa aaaagtgatc caaactggtc
     2521 aggatacagt attcatgact cacggtcatt tatcgaatgt ccgatttggt ttgacacagt
     2581 tagcaatcga agctcgagct gcaactgccg atatggtgtt ttttggtcat acccatcaaa
     2641 taggctgtga gatggatcag aaaatcctgt ttttgaatcc tggtagcatt tctcagccta
     2701 gaggcccgat ccaaatccca tcatatgctc ttatcgaaag tttagatgac caaatttctg
     2761 ttcaatacta taaccgtgcc catcaggcag ttgaagagtt ggccttttct ttttcgagag
     2821 agcgctgaat aaaaaaactc taatttttaa taaaaataag ctttatttta tgaattttgc
     2881 atccggtttc ggtaaaatag tagtgttgaa tgaaatagaa atggaggcca tcagatgatt
     2941 ggacctatag taagagaaat gctgctggaa aatcaggaaa cgtttttgat tcctgcagaa
     3001 aatgtggcaa atgttatgta tcatcatcca ttgtcccatg gtttacttgt gttatcgaag
     3061 gtcggttatt ccaaaattcc tgtattagga aaagatgatc actttgtagg actagtaagt
     3121 ttatcagatg tggtcaataa aatgattgac ttgcaaacaa tcagcatgga cccgttagaa
     3181 ggactaacgg ttgctgatgt gacagaaaca gatgttccga caattgatga aaattgggaa
     3241 ctagaagaag tactccattt gttagtcgat tcgccttttt taccggttgt cacagaagat
     3301 cggattttca aaggaatcat tacaagaaaa gagctgctta aagccgtaaa cttcatggtg
     3361 catgaattag aacgtcgtaa tatattgtct ccgaaaatcg aagaattaaa agaacaaatc
     3421 gatatcgtga gctaaagaac gagaaactaa aagataatca aaaaataagt agaaaaaaca
     3481 gcgtaccagt tttgacttta tcttgaaaaa gaggctggga caaaagcgtt taactccaag
     3541 aaataagaag gaattcacga aaattgcttt tcaaattttt gtgaatttca gcttatttcc
     3601 gaaggagttg cttctgcttc cgccgtttat acgtgtttag agcgtgggac aaaagtgttc
     3661 tttacttttg tcccacgctc tttttagtga gattcgttgc atcgtttgtc caaattattt
     3721 tccgacagca attggactgt tcggaatcgt gaaaccagaa gctgtcaatt ctttgacata
     3781 ggagctcaag aactcttctt ttaaggcata ttgttttccg ttcaatgcgt agcagaccgt
     3841 acgaatcgca aaattgctgt ttccaagatc cactaatcca aagatagaag gttcagtttg
     3901 gagctcttct tggtattttt cagctaatgt acgatttact cgatcaatga tctcatagat
     3961 tttgtcatat ccttcttcag gaacaatccg aatatctaaa agtacttgca tatttgcacg
     4021 agagagattg ctgatcgtgg tgatgtttcg attcgggatg aaatggacag taccatccgt
     4081 tgctttcagc tgaagggtac ggataccaac agatacgacg gttccttcaa tcgttaagtt
     4141 tgctagcttg atgtagtccc caacatccat ctgttgttcc atgataataa aaaatccggt
     4201 aataacatca ctcatgaacc cttgggcacc aagaccgatt gccacacctg caattccggc
     4261 accagccaaa agtgatccga tcggcacacc gatagcagat aaaattgcat agataaaaaa
     4321 gaaaccaagg gtataatgaa aaatagtatt taaaagacta tgtaaagtct ttaagcggct
     4381 ctcgtttaga atggcttttt tagaatactg attaaaagac ttatcaatca gatattttcc
     4441 cacacggtga agaatccaaa aaaggacgat caaaaaaatc agatataaac ttttttggat
     4501 aaaggcagcc aaaatggcgt cccaatcaat cccgtcccaa aaccgctgaa acgcatttac
     4561 tttgctgaca gcttgatctg tcaatgtctc gccagaagag tctgtcgtac cggcagttgc
     4621 taataatgaa aacataaaat cctcttttct aaaatttgat tctttctgta ttgtaccaag
     4681 aagttttcaa aaaaggaaat agcaaaaata actataatga aggaaaaaag ctgaaaataa
     4741 aatgacaaat aatatggata atgataaaat gtggagaaaa taacgaaggt ggtaagtata
     4801 tgcaaatcga ttggaacaat ctaggttttt cttatatcaa aactccttgg cgttttattg
     4861 ccaaatggaa agacggacaa tgggaagaag gagaattgac agaagataat tacctgacga
     4921 ttcatgaagg ctctccagcg cttcattatg gtcagcaatg ttttgaaggt ctaaaagctt
     4981 atcgtcgaaa agacggcaag gtcaatctct ttcgacctga acaaaatagt cgacggatga
     5041 atcaaagtgc tagacgattg ctgatgccaa tggtccctga aaagatgttc gttgatgctg
     5101 tcaagcaagt ggtaaaagca aatgaagatt ttgtgccgcc ctatggaaca ggcgctacat
     5161 tatacttgcg ccctttactg attggggtcg gtgaaaacat tggtgtccat ccagctccag
     5221 aatatttatt tgtcgtcttc tgtacgccag taggagcgta tttcaaaggt ggactaaaac
     5281 caacgaattt tattgtatct gattacgatc gtgctgctcc taaggggact ggtgcagcaa
     5341 aagtcggcgg aaattacgca gcgagtttac ttccaggaac agaagcaaaa gaactggatt
     5401 actcagattg tgtttatctt gatccagcca cacatacgaa aatcgaagaa gtaggtgcag
     5461 caaatttctt tggaattaca aaagacggaa aattcatcac tccgcaatcg ccctctatct
     5521 taccaagtat cacgaaatat tccttgttgc agttagctga agaacgacta ggactgcaag
     5581 caattgaagg agatattttc attgatgatc tagatcaatt tgcagaagct ggtgcatgtg
     5641 gtacagcggc tgttatttct ccaatcggtg ggatttatca caataacaat cttcatgtat
     5701 tttatagtga aacggaagta ggaccagtaa caaaacggtt gtatgatgaa ttgacaggta
     5761 ttcaatttgg agacatagaa gcaccagaag gctggattga agtcgtggaa taatttcaaa
     5821 gtaatgagtt gaaaaaaacg taaaaagaaa aaatcaggaa gagactttaa aaagtttttt
     5881 cctgattttt atatgtttta ctttaaagaa tgcaacaaaa gtttatgaaa gatggacacc
     5941 tttgtcaacg tagataatat caccgatgat tccgctggaa agtgggctga ttaagaaagc
     6001 acaagcatta ccgacttctt cgatcgtcac accttgctga tcaggcgtac gagattcaga
     6061 taactggatc agtttttgat agtctttaac acctgtgaca gctaatgttt tgattgcccc
     6121 agctgagatt ccattgaccc gaattccttt aggcgagaac tcagctgcca aataacggat
     6181 agcagcttca agagaagctt tcgcaatacc catcatgtta taattcggga ttgcgcgttc
     6241 tgaacctaga taagtcatgc taacgatccc gctgtttggt gcaagaaacg gttgtgcgta
     6301 ttttgataca gcaattaaag agtagctgct gatatcttga gctaattgat agccgtctct
     6361 ggaaatatca gacacatttc cggacaattc ttctttgttg gcgtaagcaa ctgcatggac
     6421 aaggccgtgg atctccccag catattcacc gatggcattc attgcttttt cgatgctttc
     6481 gtcgctagaa acatcacatt ctacagtgaa tgcttcttcg ccgaccaatt tgactaatga
     6541 ttttttcatt cgttcatttt ggtaagtata gataatttct gccccttgtt tcaacattgc
     6601 ttcagcacaa ccccaagcaa tgcttttttt gttagcgacg cccataatga cgattttttt
     6661 tccttctaga aatgacataa tgactctcct ttgtttctga taaaaatttg atagtcgtaa
     6721 aaaaatagag aataatagct aaaataactt cttgatttct taattattag tcaaaatgtt
     6781 ttgattgtca aactattttt tcttaaatta aaaaaagatt gctaaatatt taggaatatg
     6841 atactttgat agtcaaagta atgaaaatgg caattgcctg aaagaaggag tttaattatg
     6901 tcttacgtat tatctgctac tgaagtaatg gaattgattc ctaatcgtta tcctatttgt
     6961 tatattgatt atgtagatac tttagaacca ggaaaaaaga tcgttgcgac aaaaaatgta
     7021 acaatcaatg aagatttttt ccaaggtcac tttcctgaca atccagtgat gccgggtgcg
     7081 ttgattctag aaacactggc acaagcaggt tcgatactta tcctaaaatc agaagagttt
     7141 ctaggaaaaa gagcttatat cggtgggatc aataaggcca aattccgtca aaaagttgtt
     7201 ccaggagatg tgctgaaatg tcattttgaa atcaccaaaa tgaagggatc agtcggtaca
     7261 gcgttatctg cagcatatgt agatgataaa aaagtctgtg agtgcgagtt cacgttcatc
     7321 gtcaaccaaa atgcttgact ataaaacctg atatagcaaa acaaaaggaa gcttacttgc
     7381 tttttatgta aaaagaagac gcctgaatcc tagcatacgt tgtcatctat gcaggattca
     7441 gacgttattt ttttattttt gttttgcttc ttgcagtata ttgattttat cgatttttac
     7501 ttcttctttt ggtttgtctg aactatctgt ttcgatattt gcaatagcat ccacgacatc
     7561 cattccttca atcacttggc cgaagacagt ataatggcca tctagtgaag gataaccgcc
     7621 gtttttataa gcgtcgatga ttgcttgagg atagtcgtct tttaaaagac catcatgcat
     7681 atcatctgta ttttgaacga taaagaactg gctgccgtta ctgttaggat cttgtgagcg
     7741 agccatagat aacgcacctc ttatattata aaggtggttg ttgatctctg tttcaaatcc
     7801 ttctccccaa atgctttccc ctccagtgcc atcgccttta ggatcgccac cttggatcat
     7861 gaaatctttg atgacgcgat ggaaagtcag tccgttgtag taaccgtctt ttgcatgtgt
     7921 cataaagttt tcaaccgctt ttggtgcgtg ttcgggaaat aatttgattt tgattgtgcc
     7981 tttattcgtc accatttcga ccagatcttc attttcggcg acatctttcg tcaattgtgg
     8041 taattccaat gcgttcaaat cgacgctact ggcagtcgtg ctttccgcag tagatgtact
     8101 ttttgaactt tctgtagacg aactagaaga agtcgtgttg tttgcagaac aaccagcagc
     8161 aaacagcaat gctgctgcta aactaatact taaaataact ttatttttct tcataactgt
     8221 tcctttccaa tttactattt tgttatcttt aatgataaca aaatagaggg aaaataccta
     8281 cttaaattat tggaatttat catttatttt aaaagaaaaa gaaaaggtgt agaccattta
     8341 ctttgtgttt gctataatgt aagtggatac aaaaacgaaa agatgcagga ggaaatggta
     8401 atatgggaaa attaggaatc tcgatttatc cagaacggtc aacatttgaa aaggacaaag
     8461 cgtacttgga tttagctcat aagtatgggt ataaacgggt ttttaccagt ttgctgcaga
     8521 tcaatgatga taaagaaaaa gttctttcag aatttaaaga agtagttgat tacgcgaata
     8581 gcctaggcat ggaagtaatg gttgatatca atccagcgtt atttgaacag ttggagattt
     8641 cttacgatga cttatctttt ttccataaga tgggtgccta cggggtccgc ttagatatcg
     8701 gattcacagg agcagaagaa gcaaaaatga cgcgcaatcc ttttggtatc aaaatcgaga
     8761 tcaatatgag ttcgggcacg aattacgttg acaacatcat gagttattcg ccaaacacgg
     8821 ataatttatt aggttctcat aatttttatc ctcatcgata ctctggttta ggatacgaac
     8881 actttgtttt ttgttcagaa aaattcagaa aatataattt gaatacgatg gcattcgtca
     8941 attcgcaatc tgctgagttt ggcccttggc ctacgcaaga tggcttgtgc acgctggaag
     9001 accaccgaga tcttgaaatt gcgacacaag tgaagcattt aatccttaca ggattgattg
     9061 atgatatttc tattggaaat gcgtacgcaa gtgaagaaga attgaaagaa atggcagaag
     9121 catttaacgc ggattatcca acattgaaag tagatacgga agaaggtatt acagaaaacg
     9181 aacgaatctg cttgtttgat aaccttcata gttatcgagg ggatcgctca gaatatatcc
     9241 ttcgttcaac gatgactcgt gtatactaca aagataaaga tttcccgcct cataatacgc
     9301 gagatatgca tcatggggat gtactgattg acaatgaagg gtacggtcaa tacaaaggag
     9361 aaacacaaat cgccttgaag gatatgaaaa acgacggacg tgtcaatgtt gtaggaagaa
     9421 tctccgatga cgaattattc ctccttgact ttttgaaacc atggtcaagc tttaaattaa
     9481 ttgaaaataa aaaatagata attagttatt gcagaaataa tccgctagaa atagccagtt
     9541 atttctgctt ttttattttg tttttttata g
//
LOCUS       DAYNVV010000087         9546 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.090, whole genome shotgun sequence.
ACCESSION   DAYNVV010000087 DAYNVV010000000
VERSION     DAYNVV010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9546
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.090"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            258..1796
                     /locus_tag="ACGXWR_002579"
     CDS             258..1796
                     /locus_tag="ACGXWR_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HFK0804063.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            1793..2758
                     /locus_tag="ACGXWR_002580"
     CDS             1793..2758
                     /locus_tag="ACGXWR_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0804064.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            2745..4067
                     /locus_tag="ACGXWR_002581"
     CDS             2745..4067
                     /locus_tag="ACGXWR_002581"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFK0804065.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      4130..4234
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            4308..5051
                     /locus_tag="ACGXWR_002582"
     CDS             4308..5051
                     /locus_tag="ACGXWR_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0804066.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            5066..6058
                     /locus_tag="ACGXWR_002583"
     CDS             5066..6058
                     /locus_tag="ACGXWR_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFK0804067.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            6070..6807
                     /locus_tag="ACGXWR_002584"
     CDS             6070..6807
                     /locus_tag="ACGXWR_002584"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0804068.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            6797..7519
                     /locus_tag="ACGXWR_002585"
     CDS             6797..7519
                     /locus_tag="ACGXWR_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFK0804069.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(7603..8226)
                     /locus_tag="ACGXWR_002586"
     CDS             complement(7603..8226)
                     /locus_tag="ACGXWR_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFK0804070.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQP
                     VVQETVQTEKQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYI
                     GRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            8621..9313
                     /locus_tag="ACGXWR_002587"
     CDS             8621..9313
                     /locus_tag="ACGXWR_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFK0804071.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT         3194 a         1601 c         2007 g         2744 t
ORIGIN      
        1 aaataaaagt tgtgtgtgta aaaaagatat agctgattcc aagtgacaat ttcgtataga
       61 tttttatggt attcgtagtg aaaaaacgag aaccaaaaag ttgatccgac tttgttgctt
      121 ggattctttt tttgtcagca tatttagagg tatttttttc ttttttttgt tcgtgctgta
      181 aggttaaggc aagacaagtt agttgggaaa aaggaaagaa atgtttatac ttaaagaata
      241 acagaaagga aggtcgcatg aataatttta tacaaacatt aagtgaaaga aaaggcgagt
      301 tgctggaagc tgcatttcaa catctgtcca tttctctcat ttctttgctg attgcagcac
      361 tgattgctat tcctttagcg atttgggcag ccaatcataa aaaaatggca gaagtcttat
      421 tgcagatcac gggtgtgctc caaacgattc cttcacttgc cttattaggt ttacttatcc
      481 catttgtagg gatcggaact gttccagcat tgattgcact tgttatttac gctttgcttc
      541 cgattttcca aaacacgtat attggtctag ctgaaattga cccgtctatt gaagaagcag
      601 cggtagcatt tggtatgtcc agaatgagac gcttgctgaa agtagagctt cccatcgcat
      661 tacctgtcat tatctcaggt atccgaactg ccttagtttt aatcatcggt acggctactt
      721 tggcagcatt gatcggagca ggtggattag ggacatttat tttgttaggt attgaccgaa
      781 atacacctgt tttgacattg attggtgcga tcagttctgc cttgcttgca attatattca
      841 gcggactgat tcgctggttg cagcataaga aacctcgata ttccatcatt actttagcag
      901 cagtggtgtg tttatttggc ggcgtttctt tatatcagtc tgccttgttt aaaaatgaaa
      961 ccatcacgat tgctggaaaa ttaggagcgg aacctgaaat cctgatccaa atgtataaag
     1021 aattgattga agacaacaca aaaacagaag ttgaattaaa accgaatttt ggcaagacga
     1081 gttttttgtt caatgcactg gatcaaggtc aaatcgatat ctatcctgag ttcacaggta
     1141 ctgtcctaga aagcttggtg aaggtacctg aagcaatgaa aagtgctgat ttgacaaaag
     1201 aaaaaacata tgacgaagca gaagaattat tgaataagca attcgatatg acattattaa
     1261 aaccaatggc ttaccaaaat acgtatgcct tggcagtcaa gagatctttt gcgaacgaac
     1321 atcaacttaa aaagatttcc gatttggcag ctatctctga tcagatcaaa gcgggattca
     1381 cactggaatt tattgatcgt tcagatggat ataaaggaat ccaagaagca tatggcttga
     1441 atttttcaag tgtacaaagc atggagccaa gtttgcgtta ccaagcaatc aataatggag
     1501 atgtcaatat tgtggatgcc tattccacag atagccagct caaggagtac gatctagtga
     1561 ctctagaaga tgatcgaggg ttattcccag cttatcaagg cgcaccgctg atgaaaaaag
     1621 attttgctaa agaacatcct gaaatcgtta aagcactgaa taaattaagc ggaaaaataa
     1681 cagaggatca aatgattgat atgaattacc aagtcaatgt cgaaaagaaa aagccgacag
     1741 aagtagcacg aatcttcctg aaaaatgaag gattagtaaa ggaggaagat cagtgactaa
     1801 attaatcgag ttcaaacatg tgcaaaaaaa gtatgatgga aagtatgtca tcgatgacct
     1861 aaatctggca atcaaaaaag gagaaatctt tgttttggtt ggtccttccg gtagtggaaa
     1921 aacaactact ttgaaaatga tcaatggatt atctaaacca tcagcaggag acatctactt
     1981 caaaggaaaa tcgttaaatg aatataatct gcagaaaatg cggtggaata tgggatatgt
     2041 gctgcagcaa atcgctttgt tcccgaccat gacagtcaag caaaatattg aagtcatccc
     2101 tgaaatgtta ggttgggaaa agcagaaaag agcagaccgt gtagatgaac ttcttcaaaa
     2161 agttggctta tctcctgata tttatcgaga tcgtatgcct agagagttgt ctggaggaga
     2221 acagcaacgg atcgggatca tccgagctat tgctgcaagc ccagatgtga ttttgatgga
     2281 cgagccattt agcgcattag atccgatttc aagaaactca ttacaagaat tggttttgtc
     2341 cttacacgaa gaattgggca cgaccatcgt tttcgttacg cacaatatgg aagaagcaat
     2401 caagctaggt gatcgtattg catttatgaa ggatggagaa attatccaat gtgacacacc
     2461 agagcagtta ttgatgaatc ctaaaaacga ctacgttcgg catttctttg atgaaccgaa
     2521 acagacgaaa gagtggcgag tagaagattt agtcgtcaat ggatatttct taaatgaaat
     2581 accagaaaat gctcgtcaac aagtttgctt tgatacgcct atgaaagaag tatattcgct
     2641 tctttcggtg tatccaagca ttgtgatagt agaaaagcaa agaagtattg ggtcgctgac
     2701 aagtaaagaa atctttgctt ttttaagtcg agaggaggaa ggaaatgaaa acatatgatg
     2761 caatcatcat cggttcaggt gtgagcggct taagtgctgc ttatggattg aaagaagcag
     2821 gtaaaacagt actagtggtc gaagaagatc tatggggcgg gacttgtcct aaccgtggat
     2881 gtgatcctaa aaaagtcttg ttaagtgcag tagaggcacg taatcgggta aaacaattga
     2941 gtggaaaagg ttttaacgag atcccaactg ccaactggga agaacttcaa aaattcaaac
     3001 gaacatttac ggatccagtc ccagaaagcc gaaaaaaaca attagcagaa gctgaaatcg
     3061 atcatctttc aggaaccgct cgttttttgg atgattcatc tattgaagtc aacgaagaag
     3121 tcttccatgc ggattactta gttttggcaa ccgggcaaag acctacgatc ttaccagtgg
     3181 agggaaagga atacttgaaa actagtgcag actttttatc attgcctgta ctgcctaaag
     3241 aaatcatttt tatcggtggt ggttatattg cttttgagct agctacgatt gccaatgctg
     3301 cagggagcaa agtaaccatt gtccatcata atcaacggcc attaaaagaa tttgaggcgt
     3361 ctttggtaga ggaagccgtc catcaaatgg aagcatctgg cattcagttt gcttttggtg
     3421 ttgaaaccca aaagatcatt tcagaaggta ctcgctatcg tttagtcgga aaagagacgg
     3481 aattagtagc agatatgatt ttttgtgcga ctgggagaca gccgaataca gaatctttag
     3541 cacttgagca agcgaatatc gtctttgata aacacggaat tgcagtcaat gattatctgc
     3601 aaacgagcaa tccaaaaatt tttgcgtgtg gagatattgt ttcaaggaaa accccaaaat
     3661 tgacaccagt cgccactttt gaaggaaatt atgtagctaa gcggataacg gatgcaacaa
     3721 gcgaacctat caaatatccg attataccta cgatcgtcta cgccagtcct aaacttgctg
     3781 aagtaggagt tacaaaaagt cacgcctctt cgtcagatca agtggtagag atggatctta
     3841 ccagttggtt cacctatcat cgtgtcaatg aaccagttgc taaggctgaa ttgacctttg
     3901 accagcaaaa ttatttgatt ggtgctgcag tgattagcga gcaagcagac gaattgatcg
     3961 atgatttgac actcgtcatc aatcaaaaat tgactaaaaa agagttggat agctatatca
     4021 tggggtatcc gacattggca agtgatctct cctatttatt gaaataatca gcatgataac
     4081 taaagcgctt gttgcttttt ccttcttgtg ctacacttta aaaaatgaat acctgtttct
     4141 ggggatgtcg tagacgacat gagagtaagt tgtgaactta gacccattga acctgtcagt
     4201 taatactggt gaagggagaa acatagcaga cgcttgaagc gggttactat gtcgtgccca
     4261 tttcaagcgt tttttgttat tcatattaga agaaaggagg taacaaaatg aagaaaaatc
     4321 tttatccagc agtcagtatg gcattcattt taattatttg gcagattgtt gtcatagttt
     4381 ggaaaatacc tgcctttatt ttacccggac ctgctgctgt attttctgca ttagcggcag
     4441 atgcacaagt attactttcc cattctgtca cgacattaaa tgaagcagtg cttggtttgg
     4501 taatagctag cgttctttct tttattactg ccttggcaat ggattattgg aagtttttag
     4561 aaatgtcttt ttatccgtta ctagtgattt cacaaatgtt gccaatcatg gtgttagggc
     4621 cattacttac cctatggttt ggtttcggta tgcttccaaa agtgatcctt gttgtcttga
     4681 taagctattt tccgatcgta gtttcttttt cggatacatt gaggaaagta tcaaaagagc
     4741 aaatcatctt tttgaaaacg atgggggcag atacagggaa gatttatcga atatataaaa
     4801 taccagcggg tttatccggc ttcttttccg gtttaaaagt ggctgctact tattgtgtca
     4861 gcggagcagt cgttggagaa tggctaagcg ctcaagcagg cttagggtat tacatgatac
     4921 gcgtaaaaaa cagctaccag atcgataaag tttttgctgc gatcatttgt gtcattctat
     4981 tgagtttatt gctgaatggc gcttgttcat tattgaaaaa agggtattat cgtatgcttt
     5041 atatttttta agagaagggg atcaaatgaa aaaattatgg cttttattac cgctactgtt
     5101 gcttttatcc gcttgtggca ctgcaaaaga aacaagtagc aaacaagaaa taaaggattt
     5161 gaaaaaagtg acacttgttt tggattatgt accgaatact aatcatactg gcatctacct
     5221 agcaaaagaa aaaggctatt ataaagaggc tggtttaaat gtccaaatca tcgaaccagg
     5281 agataattcg acaagtattg gtctagtagg tgcggacaaa gcacaatttg gtgtaagtta
     5341 tcaagaagat gtcacttatg ctcacgcaga tggacagaat ataccagtca aagcaattgc
     5401 tacagtgatc aaacataata cttctggatt cgccacccta tcagacagta acatccattc
     5461 accaaaagat tttgaaggaa aaacatatgc aggttggcaa agtccaagtg aagaagctgt
     5521 cttaaaagct gtgatggaaa aagacggcgg ggacttttca aaactgacaa tggtaggaag
     5581 caatggagaa gggccagaaa gcttaggaaa atcctcagat atccaatggt actttgaagg
     5641 ttgggatatg atcaaagcaa aagaagcggg tattgaacta aactatatcc cattgaaaga
     5701 attagatgaa cggttagatt actatactcc ggtaattatt acgaatgatc aactgatcaa
     5761 aagtgatcca gaattggtac agtcttttat ggatgccacg aaaaaaggct atcaggaagc
     5821 tattaaggat ccaaatgaca gtgctaaact gttgcaaaaa tatgcaaaag aaaatgatcg
     5881 gacgttttta gaagaatcac aagcattctt gtcaaaaaat tatacggatg atcctgagaa
     5941 ttggggattg atggaagaaa aagtttggcg caattataca gcttttatgc aggaaaacgg
     6001 attgatcaag caagatgtac cttcgcaaga actattcact aatcagttta taaaatagga
     6061 gtgatagata tgtcaatcca aatcagccac ttgaatgtag tcattgaaaa cctgaaaata
     6121 ttagaagaca tccatttcac tatccctaaa gataccttta catcgattgt cgcgccaagc
     6181 ggagccggta agtcaacatt gctgaaaact ttaacaggag tccagcctat gacttctgga
     6241 acgatcaaag tagacgatca aaaagtaact ggtctccata cagcatttag ttatatgccg
     6301 caagaagata tgttacttcc ttggctgagc gtctatcaaa acgttacgtt atatcaaaaa
     6361 atcaatcatc taacaatcaa tgaagaacaa gtaagggatt atctggatat ctttgggtta
     6421 aacggctatg aacatttttt gccggaacaa ttatctggcg ggatgaagca gcgaacggcc
     6481 ttgttacgaa caatcatgaa tccttcttct tacttgcttc ttgatgaacc atttggagcg
     6541 ttagatgcta tgaccagagg gcagatgcaa gactggatgt tgaagctgcc taaaaaagca
     6601 aagcggacta ctttacttgt gacgcatgat atcgaagaag caatttattt atcagacagg
     6661 attcttgtgc tttccgcccg tccggcacat gtgattgctg agattcaagt gcctgaaaaa
     6721 cgacggtcac gtgaatggct actgcagcaa tcagagttga agcaaacgat ttatcagtta
     6781 ttggcaggtg aattagatgt taagtgatgc tcattgtcat ttagatggga gtcagagttt
     6841 agcactcctt cagcaggaac acacgatttt gacgatcatc aattgtgatt cgccagaaga
     6901 atggaaggaa aacagacagc ttgcagcaag taagactcaa gccttaagtt acggtatcca
     6961 tccttggaaa gcagatagct atacgtttga acaagttgag ccttttttga aaaaagcaag
     7021 gatcatcggt gaaatagggt tagataatat ttggacgaat gtaccgatga ctacacaaaa
     7081 aaaagtattt gagcgacagc ttgcttttgc agccataaat gagaaacctg ttgtactgca
     7141 cacaaaagga tgcgaaaaag agatcttaaa ttatatccaa gcttacccta atcactattt
     7201 gatccattgg tattcttctt tggactatca acaagactat attgatttag gctgttattt
     7261 cagcattggt cttgatttga aaaagaatcc agcagtctgg caactagcta aagcagtccc
     7321 aatcgaccac ttacttattg aaacggatgg actacatgca gcagagtggg ctttaggggg
     7381 gattttttca gaaaaagatt atgtctcact gcttgaagaa cagttaaaga caatcgctga
     7441 gatcaaagag ctatcagttg aagaagttaa aaaaaatact tatcaaaact tggaacgttt
     7501 cattagatta ggtaaataaa aaagagatgt gacacaacta gtgtcgcacc tctttttggc
     7561 tttctttgta taaaagtaaa ctgtttgatt aataaatgaa tcttagtacc aaccgtttgc
     7621 ttcccagaat gctttcgccg cttcccaaga accataacgt gaagtaacat attgttctgc
     7681 tactctttct tggtttgcag cagagtagtc accatttaag taagaagaat ctaattggta
     7741 acgtccgatg taacgtccgt tcgttgctgt gtaagaaccg cttgattctt tttgtgcgat
     7801 ccattctttt gcagagcttg tgcttgctgg agtagcagca gtttctgtta cagcaggagc
     7861 aggttgtgtt tcagcaacag gcgctgcttg tttttccgtt tgaaccgttt cttgtacaac
     7921 aggttgttca gcttggactg gtgcttcttg aacggctgct tgaggttcag cagctgcttg
     7981 tgcagagcct tctgttggga ttgttaattg ttgtcctgag taaatcaggt taatatcaga
     8041 aattgaattt gattctgcaa tggcattgat caaggagtta tcaccaacgt atttttgaga
     8101 aatcgttgat agagtatcac ctgattgaac ggtataagct tcgtccgcat gagcagtcgt
     8161 tcccatgaag aatgcagcgc cggcagccaa agttgttcca aaaagtaaag ttttaagtga
     8221 tgtcatgaaa aatctccttt attcgttaaa aagttttatt tgttgtgttc aacgaggaat
     8281 actttaacac gtgaaaatat ttcataggta aaagaagcat gacaatttat gacaaatccg
     8341 cgttttttgt aataaataca gtaatctatg aaatgaaaag ggttacgttt aataaaactt
     8401 gcttttttgt ttttgttcac cataaatatt tatttaagaa agtattaacc tgcatttttc
     8461 tctataaaaa agatttttta aatagataaa aaaggaggat taaatgagta tttgatagta
     8521 tttatattaa aattacatat gtaatttaaa aacgcttgac attgtgtttg agatcactta
     8581 cttttagcat gtaaaagtat tggattaagg agctatgcaa atgaaaaaga aatttattac
     8641 tggtgggatt gtcgttgcat ttctatgtct aattggctac acaggcacgc ggtacgcaaa
     8701 tgaaattatt ttgtggggtg gagagacaga tattgataca atcaatgaga atctgacaca
     8761 gcttgatcat acattgacag ataaagagca agcgattaca gatcttaccg ctcgactagc
     8821 acaaaaagaa cagacattgc aagattcaaa ggcagatgtc caagaatacc aaacaaaagt
     8881 aaatgaatta gaaaaccaaa aaaatcaatc ggcagcagaa aaacaaaact tagaaagtca
     8941 attagtcagc aaggatgcac aactacaaag caaacaaaat gaaatcaatg tcaaactaga
     9001 tgagatcaac caaaaaaatg atgaaatcaa tcatctgaat gcagattgga cagcaagact
     9061 acaagaagca caagcaaaac tttcagaatt acaaaatact gtaaatggtt tgaatcaaca
     9121 aatcgcaaca ctgacacaag aaaaaacaaa tgtagaaact cagttaacag atacacaaaa
     9181 gaaattagac gaagcaactg ctgaaaactc aagcttgaaa caatatattc aaaagttaga
     9241 aaaagcaaaa gatgaagtgg aagatacagc tgataaatct cagcaaattg ttgaagaaca
     9301 tttgcgtaaa taatctttct taacaagtaa acctaaatta gtaaagaagc aacagtaatc
     9361 tatactaagt agttcagttt tggagtacaa aatgacaaaa tgtacttcaa aatggactac
     9421 ttttttcatt ttaacttaca taccaaatta catacaaaat gatttataaa atgcaattga
     9481 aaatgataat tgaatgaaaa tttgtgattt tgtggtatta tgataatata acttatagaa
     9541 aaaatt
//
LOCUS       DAYNVV010000088         8937 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.091, whole genome shotgun sequence.
ACCESSION   DAYNVV010000088 DAYNVV010000000
VERSION     DAYNVV010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8937
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.091"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(25..318)
                     /locus_tag="ACGXWR_002588"
                     /pseudo
     CDS             complement(25..318)
                     /locus_tag="ACGXWR_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HesB/YadR/YfhF family protein"
     gene            complement(346..1011)
                     /locus_tag="ACGXWR_002589"
     CDS             complement(346..1011)
                     /locus_tag="ACGXWR_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HFK0804072.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(1151..1783)
                     /locus_tag="ACGXWR_002590"
     CDS             complement(1151..1783)
                     /locus_tag="ACGXWR_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFK0804073.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(1790..2857)
                     /gene="liaS"
                     /locus_tag="ACGXWR_002591"
     CDS             complement(1790..2857)
                     /gene="liaS"
                     /locus_tag="ACGXWR_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     LiaS"
                     /protein_id="HFK0804074.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(2854..3585)
                     /gene="liaF"
                     /locus_tag="ACGXWR_002592"
     CDS             complement(2854..3585)
                     /gene="liaF"
                     /locus_tag="ACGXWR_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HFK0804075.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(3754..4233)
                     /gene="greA"
                     /locus_tag="ACGXWR_002593"
     CDS             complement(3754..4233)
                     /gene="greA"
                     /locus_tag="ACGXWR_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HFK0804076.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(4369..5544)
                     /gene="mltG"
                     /locus_tag="ACGXWR_002594"
     CDS             complement(4369..5544)
                     /gene="mltG"
                     /locus_tag="ACGXWR_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HFK0804077.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            5748..6917
                     /locus_tag="ACGXWR_002595"
     CDS             5748..6917
                     /locus_tag="ACGXWR_002595"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFK0804078.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(7184..8818)
                     /locus_tag="ACGXWR_002596"
     CDS             complement(7184..8818)
                     /locus_tag="ACGXWR_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFK0804079.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTFKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT         2840 a         1698 c         1326 g         3073 t
ORIGIN      
        1 aaaattgtgt caccctctct ttttttattg ttttttaaag tgataggttg gctcctccag
       61 gttgggatca taatcaacaa gtaaatcata tcctttaaag aaccattcat ctgcttcctc
      121 gataaaaaaa agtgtcccat caatttccac tttctttaca ggatgttctg gctgttcaac
      181 tgacattcca atcgaaaaac catcatgaac ctctgttttg ccgtagactt ttcaaaaaaa
      241 acgtattccg taagtttctg gcagatcaat ttctgagtca aaccactttt gtgcttttgg
      301 cgttaccgtt aatttcatcc caacaaccta ctttctcttt tctttctatt gattcatctt
      361 atcgtctaga atatccacat cgcctgtctc tccaataacc agtagattat cattttcacg
      421 aacatattca tctgctgcag gagaagcgat aaccgtttga tctactcttc gtatggcgac
      481 tactgttaag tcaaaacgtt gcctgaaatt taattcagct aatgttttgt tgaaaaattt
      541 aggattggag actcggattt ctgctaaaga atatttatct gacaactcta ggtaatctaa
      601 aatattcttt gacactaaat tatgcgcaat ccttattccc atgtctcgct cgggatggac
      661 gacgcgatca gctccgatct tttcaagtac tctggcatga tactcatttt gggcttttgc
      721 taaaatattt ggtacgccca tttcctttac catcagagta actaagatac tggcttgaat
      781 atcttctcca atagcgacaa ttacatgatc gaaatttctt atgcctaatg atcgaagtgt
      841 catttcatcc tgtgcatttg ccacaacagc atgagtggct atattcatat attcattgac
      901 ccgatcttca ttactatcaa tagccagtac ttcttgacca gcttcgatca gtgttcggca
      961 gatacttccg ccaaatcgtc caagacctac aattgcaaaa ttttgtttca ccgttttcct
     1021 cctttagtat cttcttttct cagtataaca aagcctttac aaaaacaaaa gcaagcatca
     1081 ttattgtaaa aaagccaaga aaaataatag ttattttctc agcttttgat tatcctcttt
     1141 atcatcgttt ttatttcacc aaaccatgtt tgaatgcata gatagcggct tgtgtacggt
     1201 cttccacttc tagcttagcc aatatattgg aaacatgtgt ttttactgtt ttcagtgtaa
     1261 taaacaattc gtccgctatt tcctgattac tttttccttc agaaatcagc attaaaattt
     1321 cattttcccg attcgttagt tcttcatgta atacaggctc atttcgccga ctcatttttt
     1381 ccatcatttt tgttgtcact tctggttcta atactcgctc gccacgttgc gttgccctta
     1441 tagcatcagc aatttcatgt gcggtagagg tcttcaacaa ataccctgct gcacctgctt
     1501 caatggcagg ataaactttt tcgtcatcaa taaaactggt tacgataatg attttagctt
     1561 ctggccaatc ttttaagatt gcttttgttg attcgatacc atccatttct tccatgacta
     1621 agtccattaa aatgacgtcc ggtcgaagtg tcatcgcctt ctcatagcct tgtcgtccat
     1681 tttcagcttc tccaattact tcaatgtctt cttgaataga taaataagaa gagacgccta
     1741 agcgcaccat ttcatggtca tctactaata aaacttttat catccttatc tatgcctcct
     1801 tcatcaaagg gaccttgatt tctacacttg taccttgacc tttaaaacta atgattttta
     1861 ctgttccacc aataccagct actcgttctt tgatattgtt caatccataa cttcccgttt
     1921 tcgtttcatt catattaaac cctgttccgt cgtcaataat acgtaacaaa agattattgt
     1981 ctattttgtg caaatatacc tctaattcat tggctttagc atgtcttaat gtatttgata
     2041 acaattcttg aacgattcgg aacaagtgat cctcaatgga actagatagt tttacatctt
     2101 ctacatccca tttcagcgaa atctggattt tattttgcaa ttccttcaat aactgctcga
     2161 taccttgctt taaacttttc tcttctaaat tgactggacg tagatgaaga agcagcgcac
     2221 gcatctcaga ctgggaagcg ttgatgatct ctgctaccat tttcaactgc ttgcgaaaca
     2281 tttctggtgt ctcgcttttt tctgcttgct ccgtcaatgc cgacatcatc atcattgctg
     2341 caaacaattg ttgcgaaact gaatcatgca gctcacgggc taatcgatgt ctttctaatt
     2401 ctaaaatttc ttctttggtt tgtccatcta catattgggg acggctcgtt acaatttgta
     2461 attcactaga tacttcaatc attttttctt ttatcttagt gatttcctta tcaatatctt
     2521 tgatgtataa atcgtccgat gcacttggga tcggaagaag caacaatttg gattcataat
     2581 tgccagaaga aagtgcacgc agcttttctt cgattttccc gtattttgtc ttttgaataa
     2641 gtgataataa tagaaagaca attaatccta cacctaagga aatggctaac aaatggaaga
     2701 taagcggaac atataataaa cgtgcacgca gtaattctcc ccaccaatga ctttgattgc
     2761 tggcataaaa ataagtgaaa agtgaaaata gaataataag gaaagccgca atccccgaat
     2821 aaacagctag catcgctctg gatatttttc ccatcatatt cgtatcacct cgacatctcc
     2881 aatcaaggta ttagtaataa tcttcaatct acgagggttt tcatcataat cactgctgta
     2941 gattttgatt tgttcatttt tcaaagaaaa ttgctcttct tcaaacaaga catttcctac
     3001 taatgtcgca tgctctaatc ggatggctac gcccaaaggt actaagatcc gtgttctgcc
     3061 tatccctttt cttacaatca caatattatc atcttttggc aaaagcgtat tgcccaaatc
     3121 tatgatagta tcaccagaaa tgacggcgat gttgatatcg tcccattcat agacgtcgtt
     3181 tccaatacgt tggttaccga ataattgctg tcttttccgc tcattattat gtgtttttaa
     3241 ttgctctgtt tggatcatca tgatctgttt ctttcgccaa aaagcatttt tggttaaatc
     3301 tatccctgaa atctctacac ctttcagacc aataaataaa acggcaaata cagccatcat
     3361 ccataaagca ggactgttga ctaagctaaa aaaaatgacc aaacttccta atatcaattg
     3421 aaaattttga aatttagtac gaggatgttt gcgcatagct agatatatat tgaaaatacc
     3481 gaatatcact aaaagcaaaa gtccagtatt gtttacgatt tgccaaacag caaataacag
     3541 cagtagtgct tcaactacca caaaaaaacg ccaagaacta ttcatcgctc tttctccctc
     3601 ctgacacatt ctcatttcat catacctatt tttttaactg ttggctatag gactttagat
     3661 gtaagatcgt ttgttgaaat ctaaaataca caaagagaaa aagatctaga gtgtatcatc
     3721 agtaagatga actctctaga tctttcagtc agactacgct tgttctactt tgacgatttt
     3781 aactaacata tcgccacctg gagtagcaat agttacttca tcatttttac gtttgccaat
     3841 caatgcttgc gcaataggag aatcattgga aattttgcca gaaaacggat ctgcttcagc
     3901 gcttccgaca atcgtgtact cttcttcttc tccatctggt agttcgatga atgtaactgt
     3961 tttaccaatt gatacctcat ctgcatctac accgtcgtta tcgatgattt gagcaaaacg
     4021 aatcatattt tcaattgttg tgattcttcc ttcaacaaat gcttgttcat ctttcgctga
     4081 ttcatattca gagttttcgg aaagatctcc gaaaccgcgg gcaattttga ttcgttcaat
     4141 gatttctccg cgtttgactg tttttagttc ttctaattct ttttctaatt tttctttacc
     4201 ttctagagtc attggataaa ctttctctac catgtgtaac gtctcctttt ttcgataaaa
     4261 taccgcaaaa ggtaatcttt tgaggaatat agtccaaaaa agattaccac gcttttcttc
     4321 aaatgtaaat gtttttctaa aaatgatcaa tgtctagagc ctgtttttct aagaattatt
     4381 tacatatttt tccactaatt ccatatgttc ttcataagtt ttagcgaaat aaacatttcc
     4441 agtgctcgta tctgctacga aataataata gtcattttct gctggttcta atactgcctt
     4501 gattgcctct tcgcttggat tgtcaaaagg tccaggtcca tagccggtat tggtatacaa
     4561 attatatggt gaatctacag ctgtatcttc atacgtcact aattctttgt gttcacctaa
     4621 tgcgtataaa acagagatat ctgactgaag tggcatattt gctttgattc ggttaaagaa
     4681 gacttgtgca atgtttttac gatcattttc ttttacgcct tctttttcaa ctagagaagc
     4741 tagagttaaa acttcttgta cagtcaaatt tttctgcttg atagctgaat aatagttttg
     4801 catgaccgta ttcgtcttgt tcaccatttc aatcactaga tccttaagcg aagtactcgt
     4861 gtaataatca tatgtggctg ggaataagta accttccaaa cggtattttg tgttctcagc
     4921 tttagatgca ctttccaaca gttctgggaa tttttggtgc aactcgttaa agaaagtctc
     4981 atcattcact aaatctaaaa attctttctt gtctttacca gttaccttcg ctacccgttc
     5041 agcaatctga tcgatatcgt acccttctgg aatggcaatt ttcccatctg caacttttgt
     5101 tggctcagaa gtaccgcctt cttgcaactg tttgccaatc tcgtcaagag tcatattagg
     5161 cgctaactga taatagccag cttgaaagcc agttaaattt ttaaattttg tataataatt
     5221 gaaaacaatc ccgcttttaa taatattgtc cttctccaaa atctcaccaa tctgcttgtt
     5281 agaagagcca ctcgggatct cgacttggac taattggtca tctgatttat ctaaaggctt
     5341 caacccgcta tctacataac gatacacggt aaatccaaga aatccgccaa taatcaataa
     5401 tgtaagagca atcactaaaa tgatcttcct cacaatctta tcttcttttt tacgcagatt
     5461 tctccgcttg tcgattatat ctgctgtagc tgccttactg gcttcttttt tatctttact
     5521 tgggtgttgt ttgtttcctg acaaaacaac tcctccttac tatcaagttc gtaactttat
     5581 tcattataca tgatatttga attggcgtga atgattttat ttaaatattc tatcaaaaat
     5641 gtaagtagta aatccattac tataagatta aaataaatgt tatcaagata caagctattt
     5701 tagctttatt ctttctgtaa aaaagaaagg agactaaata aactattatg aaaaaaggaa
     5761 aacatgctaa aaaaagaaaa tattcatttt taatgatcgt tgtcgtgttg tttagcctta
     5821 gtgcgttctc tacaggaact attcttggat ggcaatttta caataatgaa cactctcaga
     5881 tagttgccca tgctcaatca gctcaaaaaa agttgatact gactaccaat gaacaacagc
     5941 tcgttgaaaa aatcgatcaa ctattaagaa aaaatgatta tattggctca atttacgtaa
     6001 agaaaaataa tcgcatcatc atggaaaaag gctatggcta tgcgaataaa ctcacgcaac
     6061 aaccaaatga tccttctctt tattatcaga ttggttcggt tcaaaaagca ttgactactc
     6121 ttttgatttt aaaacaagtc gagcgtgggc acctttcttt agatactaag ctggctcaat
     6181 tctatccaca aattgctggc agccagcaaa ttactatccg tgacttgctg tatatgcgct
     6241 caggcttgca ccgaactgct tctccaacca taccgatgac tgatgaagaa gtcgttcaat
     6301 ttgcgattca gcacttaaaa tttacagatt atcagacctc tcattatgat tcattgaact
     6361 ttaccatatt gactggaatt ttgatcaaat taacaaatca accgtatgaa aaattattga
     6421 ccgatgatat catcgaacct ttaggattac agcatacaaa attttatgac caagtcaaaa
     6481 attcatccaa tcatgcacta tcctatcaaa tgtctaaaga ggatgattac tttaaaccac
     6541 tgacagaatc tgaaacagag atccataacg aattagggac tggtaatatc agtatgtccg
     6601 tctatgattt aaatacgctg tttacacaag ttttatctgg aaaactagtt tccaaagact
     6661 tactcttctc attatggcgt gaaaatgcga atggacatcc atatagtggt ggggtatata
     6721 gcggagataa ttatatcctg tcgcaaggaa atatcgactc ttttgataca tctgctatat
     6781 ttagcaaaga ttcacaggat gctatcatca tggaaagcaa tataaaagct gacaaaacta
     6841 tcaaactgcc tactgctgat ctaagaaacc aaatctatga cctgatggaa ggaactacta
     6901 agttggcaaa tagctgatat gatgaaaaga tagcaaatac tacttctttg aatagcattt
     6961 gcttaaaaaa agtactcgac taaacgtagg aaagagtgtg ggacaaatct aaaaatcaat
     7021 ttttgctaca gactttaatt ccaaataaac agaacagaaa gaggtgttct tctttctgtt
     7081 ctgtccaaat tattctaaga tttctcttta ccaacattat ttgacaaagg gcctattaaa
     7141 tctaaaatag tatctttaga ttgctaaaat atgtgctagc aaatcattca tggcttgttc
     7201 ttatttttaa ttttatgcaa taaaaaagaa gaacaattag cgtgattata gaaataaata
     7261 atgagatttt agaaaaaaat gtgtatgaat acctgattgt tactttattt attccacttt
     7321 cactttttac tgtaacaaaa ggacctcctt gttttagtac tgtagcattt tttgaattaa
     7381 cagtaaccgt taatccttta taccggaata caggtaaaac tattgttttg ccttttgaag
     7441 atttaaacgt aaatgtaatt tcatctttat ttggagaaaa gctactataa ataacttgac
     7501 catcttctgt aacttgatgg tttttcaaaa gcaattgatc ttttttatag cctataggta
     7561 cataatcaaa attctcaaat tcttcaagtt tattttccat ttgttcatta gaataagttc
     7621 cttgaaaatt catttctttc accatgttaa ctactgatga ataatttaaa attgaaatag
     7681 ctaatattaa taatagtata aaatttcttc tccttgtata agaaaatttt tccaactgtg
     7741 gagaaataaa tagagatact gaaaaagata tgaacaatgt tgaaaatatc ataaaacgcc
     7801 aaggagcttg aataatattt aaaggagtat tttgtaaggc aaaccatgga aatatttttg
     7861 tacaaagtag aatagatatt atacccatta tataagtgat tttagataag attcctaatt
     7921 ttttaaagtt aaatgttagt ataattaaac aaataagcaa agttaagcca ataccaaatg
     7981 atagtaattc tgaatctata cttccaatca aaaactcttt acccagataa attgctcttt
     8041 tttgtaatat atccacataa ggtctattca gatcttgata caatgtctgc tcaatcatag
     8101 gacctataaa cgctagtgaa agaagtaaag taactatagc agcttttatt aatttaataa
     8161 ttaagaagat ttctattttc tttttccgat aaaattgaat aattaaagca attataatca
     8221 ttaccatagt catagctaca gaaagaacat gagtgtaaat taataaagtc atgctaatcg
     8281 ccaacataac ccaagattct ttttttgagt cgtaaagctt tataaacccg agtaaaataa
     8341 gaggaagtat tgacattgcg agtaattccc ccattgcccc tcgaagaaat atttctacac
     8401 tcctaaaaga agatgttgta tatataatag cgaaaaagga gctagtaaca tgttttttgg
     8461 taatttcata cattacataa tgacatataa atagagtaat gagcgtaaca atataaagaa
     8521 aaaggttata gcctattgct aaattagtaa acttgatcaa taaaaataaa ggatatagag
     8581 ttaaccatgg gtaaaaatta tttacttgca tgccatatga tctaaacgtt tcaaaattaa
     8641 taggggagct aaaaatagat tctaaactta acgcacgatt aatgtgaaat gccgtatcat
     8701 aaaagccaaa tatttccatg tttttaaatg ctggaaataa atataataaa ctaacaaatg
     8761 cataaactat aaatattttt acagaaaaaa tttttttcaa attcatatac cacctcatgt
     8821 ttttttatat tacatatagt atcatttatt tttttaaaac actagattag tcactatata
     8881 aaatgtgatt aattttatta ttaataaaat attttttata ttacaaaagt agtgttt
//
LOCUS       DAYNVV010000089         8696 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.092, whole genome shotgun sequence.
ACCESSION   DAYNVV010000089 DAYNVV010000000
VERSION     DAYNVV010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.092"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..241
                     /locus_tag="ACGXWR_002597"
     CDS             <1..241
                     /locus_tag="ACGXWR_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HFK0804080.1"
                     /translation="KLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLNEARNRH
                     SLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            302..802
                     /locus_tag="ACGXWR_002598"
     CDS             302..802
                     /locus_tag="ACGXWR_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000425404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFK0804081.1"
                     /translation="MEMKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEE
                     YAIHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENK
                     EDIHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHG
                     VFEYCQ"
     gene            858..1496
                     /locus_tag="ACGXWR_002599"
     CDS             858..1496
                     /locus_tag="ACGXWR_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6037 family protein"
                     /protein_id="HFK0804082.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            1568..1963
                     /locus_tag="ACGXWR_002600"
     CDS             1568..1963
                     /locus_tag="ACGXWR_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFK0804083.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            1947..4400
                     /locus_tag="ACGXWR_002601"
     CDS             1947..4400
                     /locus_tag="ACGXWR_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFK0804084.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            4397..6424
                     /locus_tag="ACGXWR_002602"
     CDS             4397..6424
                     /locus_tag="ACGXWR_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFK0804085.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            6421..7443
                     /locus_tag="ACGXWR_002603"
     CDS             6421..7443
                     /locus_tag="ACGXWR_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HFK0804086.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDDETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            7460..8389
                     /locus_tag="ACGXWR_002604"
     CDS             7460..8389
                     /locus_tag="ACGXWR_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFK0804087.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            8634..>8696
                     /locus_tag="ACGXWR_002605"
     CDS             8634..>8696
                     /locus_tag="ACGXWR_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="regulates the transcription of tet(M) by
                     attenuation; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HFK0804088.1"
                     /translation="MILKYPENICMLCIPMVMHKN"
BASE COUNT         2947 a         1466 c         1736 g         2547 t
ORIGIN      
        1 taaattatat agtaggatac aacaattaat tgaaaaagaa attcaaccta ctgaacttgc
       61 tgatatagtg aagacaacga taaggtcatc aaatggaatg attagctctc ttaatgaagc
      121 aagaaatagg cattcacttg cacaccctaa tacaaatatt attggaaaga gagaagcaaa
      181 actaataata ggtatttcaa gtacagttac agattatatt agcggatacc ttgataagta
      241 gcgtcattaa ctgattgcta ctttttttat gactattttt ataaaaagga tgtgataaga
      301 attggaaatg aaagtctatg tggcaaattt aggacggtat aatgaaggtg aattagtcgg
      361 agcatggttt actccaccaa ttgatgagga agaaatggca gaaagaatcg gtttaaatga
      421 ggactacgaa gaatatgcaa tacatgattt tgagcttcct tttgatgtgg acgaatacac
      481 gccgattagt gaaatcaacc gtctatgtga agccattcaa gaaatcgaag gtacacctat
      541 ttataatgaa ctcaaagaaa ttcaaggcat gtggtttagt agcttggaag aattactgga
      601 aaacaaagag gatattcatt gttatagtga ttgtgattcg atggaagatg tcgcccgtta
      661 ttacgtggaa gaaacaggac agcttggtga agtcccttcc aatttacaaa attatattga
      721 ctaccaatct ttgggacgtg atatggaaat agagggtaat tacctagtta cctctcatgg
      781 ggtatttgaa tattgtcagt aagtttaaca atccgtgtta taattaaatt aataaatagc
      841 acggagaggt ataaattatg gtaaatgtat ttgaaaatct taaactatta aaactagaca
      901 tgaaagataa aggctgggtg atagattcct tttactttcg ttacaaacag caaaattata
      961 ttgtacttgt taagctattt gaaaaagagg aaaaagttcc agaatatgct ctgttaaaac
     1021 tagaattttt aaaggaaaac gatttttcag atatgctagc tgtctatgct aattcggtaa
     1081 aattatatac agacacgaaa acaataagag aatattttgg tatcgaatac agtagtaact
     1141 tgggagatgt tttatttcaa tttagccaaa ctcttgctcg atttattccg acagaagtta
     1201 gtgagaagaa aaatgaagac caaaaagaag ccatgtgttt ctcattaagt caaagtgatt
     1261 cagaagatcc cagaaaaaaa tattgttttt cagttagaag aaatccttta aagggaaatg
     1321 gtgagctggg aaaacgaagt ccttttaatg acaataaaac gagattgtat agacccagct
     1381 tatatgaacg attagggtca gataccaatt taagtttcag atattcaatg aatccagatg
     1441 atgaagaaac tgatgaaggt attattgcaa aatggacaaa aaataaaatt gaatagttaa
     1501 agcattgaaa gagcaatcac ctattttgat tgttcttttt ctatttttac ggaaaggacg
     1561 tgaagacatg aaaaaaataa gaagttacac cagtatttgg tcagtagaaa aagtgattta
     1621 tgcgattaat gatttacaac tccctttccc aattaccttt acgcaaatga catggtttat
     1681 cgtttctttg tttgtcgtca tactctttgg cagtttacca ccactttctc tgattgacgg
     1741 agcactactc aaatacttag ggattcccat tgttctcact gggttcatgt gccaaaagac
     1801 ctttgacgga aagaaaccct atggatttct aaagtctatc attacctatg ctctacgccc
     1861 taaagtaacc tacgctggca aacaaatacg attaaaaaaa gaaacaatga atgaatcgat
     1921 tacgattgta aggagtgaac aactagatgg catatccgat taaatatatg gaagataatc
     1981 tcgtatttaa tcatgatggc gaagtattcg cttattatga attaattccc tataattaca
     2041 gttttttaag ttccgatgaa aaaattcaag ttcatgataa tttctgtcaa ttgattgccc
     2101 aaaatcgtga tggcaagatt catgctctgc aactagcaac cgaatcaagt attcgagcca
     2161 cacaggaaca atcgaaaaaa gaaatcactg gacgattaaa agagatagct tacgaaaaaa
     2221 tagatgaaca gaccgaagcg ttaatttcta tgattggtga caatcaagta gactatcgct
     2281 tttttattgg ttttaaactc tacctcaatg aacaggaagt atccgtaaaa aatgttggga
     2341 aagaaattca aaaagcattt gcggaattct ttcatggtgt gaatcacaaa ttaatgggcg
     2401 attttgtttc tatgcctatg gcggaaatcg aacgcttttc taagatggaa cagttgttag
     2461 aaagtaaatt atccagacgc tttcagattc gtaaattgga gaaagatgat tttggttata
     2521 ttattgaaca tctttacggg caaacaggtg tcccttttga tgactacgac taccatttac
     2581 cgaaacgata cgaagataaa aaagtgttgg taaagaaata cgatattctc aaacccactc
     2641 gctgtttaat cgaagaaaat caacgctatt tacggattga acaggaagat accactactt
     2701 atgtggcgta ttttacaatt aatagtattg ttggtgaatt ggatttccct aatagtgaaa
     2761 ttttttatta ccagcaacag cagtttactt tccccgttga taccagtatg aatgttgaaa
     2821 ttgtcgccaa taaaaaagcc ttatctaccg ttcgcaataa aaagaaagaa ctgaaagatt
     2881 tagatagcca cgcatgggaa agcgacaacg aaaccagtac taatgtggtg gacgctttag
     2941 aatctgtcga tgaattagaa agtaatttag accaaaccaa agaatctatg tacaaactaa
     3001 gctatgtggt acgggtatca gcaaagaatt tggacgagct gaaacaacgt tgtgatgaag
     3061 taaaagattt ttatgatgat ctgtctatca aattagtacg accttttggc gatatgctag
     3121 gcttgcataa tgaatttatt ccctcaagca agcgatatat caatgactat attcaatatg
     3181 tcacgtcgga ttttttggct ggtcttggtt tcggtgctac acaaatgatt ggtgaaaatt
     3241 ctggtattta cgtcggttac aatctcgata caggcagaaa tatttatctc caacctagcc
     3301 ttgcaagtca aggaattaaa ggctctgtaa caaatgcatt agcgtccgct tttattggtt
     3361 cattaggtgg cggaaaatca ttctctaaca atatgctggt ctattattca gtactctttg
     3421 gcggacaggc aaccattgtt gacccaaaag ctgaacgtgg tgaatggaaa gaaaccttac
     3481 ctgatattgc ccatgaaatc aatattgtta atctcacgag tgagaacgac aataaagggt
     3541 tacttgaccc ttatgtgatt ttaaaactcc cgaaagattc agaaagcctt gccattgata
     3601 ttctcacgtt cttaacaggt atttccagcc gagatagcga gaagtttcct gtcctgcgta
     3661 aagctattcg gagtgtaact caaagcaaac aacgagggtt gttattggtg attgatgaat
     3721 tgcgaaaaga agatacgccc atcagcaata gtattgctga ccatatcgaa agctttgtcg
     3781 attatgattt tgcccatctg ttattcagtg atggcagtgt cacccaatcc attagcttgg
     3841 aaaaacaact caatattatt caagtggcag atttggtctt acccgattcc aatagctctt
     3901 ttgaagaata cactaccatg gaattattaa gtgtggcaat gctgattgtc attagtacct
     3961 ttgctttaga ctttatccac tctgaccgtt ccatttttaa aattgttgac cttgatgagg
     4021 cttggagttt tttacaagtg gcacaaggaa aagctctatc tatgcgattg gttcgagcag
     4081 gacgtgccat gaatgcaggg gtctatttcg ttactcaaaa cgcggacgat ttactagatg
     4141 aaaagatgaa gaataatatt ggcttgaaat ttgcctttcg ttccactgac ctagtggaaa
     4201 tcaaaaagac cttagaattt tttggtgtgg acaaggaaga tgaaaacaat cagaaacgct
     4261 tacgtgaatt agaaaatgga caatgtttag tttcagacat ctatggtcgt gtaggggtta
     4321 tgcagtttca cccgattttt gaagagttgc ttcatgcctt tgataccaga ccgcctgtgc
     4381 gaaatgaggt ggaagaatga cacaaaaaca aaagaaattt cttcactata gttggataac
     4441 gctcctttgt gtgggcgtta ttttactttt attaggcacg ctgggcaatg cagtacaagc
     4501 gacaggctta gttgatgaaa ccattgatac aagcaatgaa tactccaagt atggtttgaa
     4561 tcaatatcag cttgattatt atgtggacaa tagctggggc tggcttccat ggaattggag
     4621 tgatggcata ggacaatcgg tgatgtatgg attgtatgcc attactaatt ttatttggac
     4681 aatttctctt tatctatcga acgccacagg ttatttggtg aaagaagcct atgccttaga
     4741 tttcattagt caaacatccc aagcaattgg cgaaaacatg cagacgattg caggcattac
     4801 accgaatggc ttttccagtt cagggtttta tgtcggtttc ctccttcttt ttattctcat
     4861 tgttggaatc tatgttgcct atacaggatt ggttaagcga gaaacgacga aagtgatacg
     4921 agctgtttta aactttgtcg tggtgtttat tctatcggct tcctttattg cgtatgcacc
     4981 cgattatatt gcgaaaatca atgatttttc caaagatgtc agtaccgcca gtctgaatat
     5041 tgggacaaaa attgttcttc ctaacacgga tagtcaaggg aaagacagtg tggacatgat
     5101 acgtgacagc ttattctctg ttcaagtaaa gcaaccatgg ctattgcttc aatatggctc
     5161 cactgatgta gaagcgttag gggaagaacg tgtggaaagt ttattgtcta ccagtccaga
     5221 tacaaacaat ggtgaagata gagaaaatgt agtgattgaa gaaattgaag atcatgacaa
     5281 tacctattta accctaccga agacgatttc cagattagga acagtcttct ttttgtttgt
     5341 attcaatatt ggtatctcga tttttgtttt ccttctaaca ggaatcatga ttttttcgca
     5401 agtgctattt attattttcg ctatgttttt gccaatcagt ttcctattaa gtatgttgcc
     5461 gagttttgat ggcatgggca ggcatgccat taccaagtta tttaatgtga ttatgacaag
     5521 ggctggtatt accttgatta ttaccgttgc ctttagtatt tccactatgc tttattcgct
     5581 gtcagcaagt tctccctttt tcatgattat gtttttacaa attgtgacct ttgcagggat
     5641 ttattttaaa ctgggcgatt taatgagcct attcacttta caaagcaacg actctcaaaa
     5701 catgggcaga caagtgtttc gcagacctcg tcaaatgatg aatcgacaaa ccagaagatt
     5761 tcaacgcagt atgagtaaga tttttcgtgg aaaagcaggg tcaacgaagc aaaagacaat
     5821 gacaacaaag cagaatcaaa ccaataaagc taaccatact cgtcaaaatg aacggactac
     5881 accaaagaaa gaaacagcac tttccaatgt gaaaaagcaa caaggcggta tcgggcaacg
     5941 attaggtgaa aagacagccc atgtattgga cacgaaaaat cgtctagtca ataaaagaaa
     6001 gcaggcaaaa caacagatac aggcgacacc aacccatgtc aaatatgccc ttcatcaagg
     6061 aaaagagaat gtcactcata atgtaacaga ctttaaacaa tctatggcag ataccaaagc
     6121 tcaacgcaaa caacagcgta tgaaccagca ggagcaaaaa cgaaagaaca ttgctcaaaa
     6181 gcgtttggag ctggataaag caaaagaaaa aagacgaaaa gaaaacccat catctcctgt
     6241 tcagaataac cagcagcatg ttcgcaagcg tcagcaaacc gtcacgcctg ttttgtcaca
     6301 aaacactaaa cgtgaaaatc atcagcgacc attgaaaaaa gagcaaaaac aaaagacacc
     6361 accgaagcaa ttcaatcaga ggaagctaaa taaaagaacg gataagcgag gacaacaaac
     6421 atgaagctaa aaataacagt gatttgtagt gtggtcttct ctctcttctt ttttctctta
     6481 ttattcctag tcattttctt tgcagatgat acggacagtg gcgaaaacaa caaggattct
     6541 tctattccac aaggcggtgt gaccgtttca ccagaagtgt tggcacaccg tccgttgatt
     6601 gaaaaatatg gtaaggaata tgggattgaa gactatgttt cttatatctt agccattatg
     6661 caagtggaat cgggcggtac agcagaagat gttatgcaaa gttccgaatc tttgggttta
     6721 ccgcccaaca gtttgagtac cgaagagtcc atcaaacaag gggttaaata tttcagtgaa
     6781 ttattaacca gtgcagaaca acaaggagtg gatatagatt ctgttatcca atcttataat
     6841 tatggcggtg gctttttaaa ttatgtgagg agtcatggga aaaaatatac ctatgaatta
     6901 gccgaacagt tttctaaaga gaagtcgggt ggtcaaaaag cagactatcc caatcctata
     6961 gccatacctg tgaatggtgg ttggcgatat aactatggaa atcagtttta tgttcagttg
     7021 gtttcacaat acctaaccga cacttcccca acagaatttg atgatgaaac cgtgcaagtc
     7081 attatggacg aagccttgaa atacgaaggg tttccctatg tctttggagg ggcgtcgcct
     7141 accacctctt ttgattgtag tggcttaata caatgggtgt atgacaaagc tggcatttct
     7201 ctccctcgtg tcgcccaaga tcagtatgac gctacgcaag aaatctctat ggaagaagcc
     7261 caagcaggcg accttatctt ctttcattca acctataatg caggcacata tgtgactcat
     7321 gtggcgatat atttagaggg aaatcgcttt tatcatgcag gcgacccaat cggttatggc
     7381 gacttaagca gtcgttattg gcaagaccat ctgattgggg ctagacgtgt tattcataac
     7441 taagaaagga atgaatcaaa tgattataaa aatcgagcga aaagaaaaga aggagaaacc
     7501 aaagaaatct aaaaaaccga gcaagcaaag aaaagttccg atgattaaag ttggcacgca
     7561 taagaaatta acctttgttt tatgggtttt attgattggt agtgtcggat ttggaatcta
     7621 taaaaatttt actgccattg acactcatac tgtccgtgaa acagaaatca ttaaacagca
     7681 gattgtcgat accaaccaag tagaaagttt tgtgaaatcc tttgcgaaag actacttttc
     7741 gtggcaacaa tcccaagaag ccattgataa acgaaatgaa aaattgaccc attatttgac
     7801 ggaagaattg caggtattaa atgaagaaat gattcgtaag gatattccta ctagttctag
     7861 tgtgaacgat atacaggtgt ggcaggtttc tcaagtgaat gagaacacct ttgaggtact
     7921 gttttctgtt gaacaagtta ttaccgaaga caaagacaag gaaactatat cgtctagctt
     7981 tcatgtggtt gtccatatag atgaatcaga taatatggtt attatcaaaa atccgacaat
     8041 gagtaagaaa cctcaaaaat cggactacca acccaaacag ctagaaagtg accatacagt
     8101 agatacagaa acgatggacg aaatcactag ctttttagaa acgttcttcc agctctatcc
     8161 taccgccaca gaaaaagaat tgacttacta tgtaagtaat catgtgttac ctatgattaa
     8221 caaggaatat gttttcgagg aattggtgaa tcctatcttt accagaaaag ataaccaagt
     8281 aatcgtgaat gtcgctgtga aatatttaga tcaagaaaca aaggcaaccc aaatctcgca
     8341 atttgagttg atattagaaa aacaagataa ttggaagatt gtaaaataac aaatattggt
     8401 acatgattac agatactttg taatcatgta ctctttttga taaaaaattg gagattcctt
     8461 tacaaatatg ctcttacgtg ctattattta agtgactatt taaaaggagt taataaatat
     8521 gcggcaaggt attcttaaat aaactgtcaa tttgatagcg ggaacaaata attagatgtc
     8581 cttttttagg agggcttagt tttttgtacc cagtttaaga atacctttat catgtgattc
     8641 taaagtatcc agagaatatc tgtatgcttt gtatacctat ggttatgcat aaaaat
//
LOCUS       DAYNVV010000090         8483 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.093, whole genome shotgun sequence.
ACCESSION   DAYNVV010000090 DAYNVV010000000
VERSION     DAYNVV010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.093"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..189
                     /locus_tag="ACGXWR_002606"
     CDS             <1..189
                     /locus_tag="ACGXWR_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804089.1"
                     /translation="APYTQERIQTTIDLQVKKLHQELLDQRNKEQKKAFIQRSMDFLA
                     PLCCLVMTLFAFWLVWGG"
     gene            191..880
                     /locus_tag="ACGXWR_002607"
     CDS             191..880
                     /locus_tag="ACGXWR_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804090.1"
                     /translation="MAFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFLI
                     GCIFSLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQALAQKIEEFTA
                     CYEDMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1001..1087)
                     /locus_tag="ACGXWR_002608"
     CDS             complement(1001..1087)
                     /locus_tag="ACGXWR_002608"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFK0804091.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            1724..2668
                     /locus_tag="ACGXWR_002609"
     CDS             1724..2668
                     /locus_tag="ACGXWR_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFK0804092.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     FTFDQLKDLSNYKATANVRFVEDLKATYEKILSLRFGRRSESGLSYDMFVMFTEFKIN
                     GDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQFNELQSGYAKTMFRLLKQYRTKGFA
                     YFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEDQNKALALADKQKEYEEPATTINEKIKQKKRELELL
                     QQIKQLEKEKKALEKQTESALSEKEKKSLLSDLDNLFQ"
     gene            2689..3222
                     /locus_tag="ACGXWR_002610"
     CDS             2689..3222
                     /locus_tag="ACGXWR_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFK0804093.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            3237..3407
                     /locus_tag="ACGXWR_002611"
     CDS             3237..3407
                     /locus_tag="ACGXWR_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804094.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(3650..4111)
                     /locus_tag="ACGXWR_002612"
     CDS             complement(3650..4111)
                     /locus_tag="ACGXWR_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFK0804095.1"
                     /translation="MEDLGSKLRELRVKKGYTQEYVARKFNVTRQTISKWENNKTTPD
                     IETLKKICEFYSTNINSILNEDNLKNKQNNLLVLTAIIFNIFVTILGLFELIQMNFFS
                     FTHGIFTWFALSGLIVIDILNYFYIYYSYLKNEKFFYTMFFPLVILIILLS"
     gene            4244..4618
                     /locus_tag="ACGXWR_002613"
     CDS             4244..4618
                     /locus_tag="ACGXWR_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HFK0804096.1"
                     /translation="MKKFLCLSALMGVLLTSGGIVSATEALNLDVPEDHTAIYGGGME
                     ATEEGFSSSKLRYAAGGGDFNCGVNGFKVYANYYHARAKHSATAKNGRGGQVRSVQKA
                     GVRAYATCNATLTGNTGWWNVY"
     gene            4672..6798
                     /locus_tag="ACGXWR_002614"
     CDS             4672..6798
                     /locus_tag="ACGXWR_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804097.1"
                     /translation="MLKKINAVLSLFVCITILFFSTNVINGIKTSEALYKNTAEIHMQ
                     YKDDMDFNSYINALYEISTQENINISQYSFTAVNQLTILATNPNANKHWKFSKKNILA
                     RNDSKVHYTNNKNSKYQLKLPNNFLNINIYPFSHVENIGLSEILYVQGNSNKLIPVLK
                     KYGTPTISNINQSDTFQINTNIVLVICYLSIFIVITTIIFAFSKMKEITLKKMLGYNS
                     FDTIKDSIKELNLLFCSLIITFILSIFLSIYYSNENFFLSFLLCSIFHFIISFLFIIV
                     TLSIYHLSSIKNYLKNSRPLKLNLCILNICLFLSMILLLIASTKVINIHNEAENNSLK
                     YWERTTNLYKTNITNQLNRNNTVEENNYLKKASKFVYKIQKNYKTFIIAPYNYATIQE
                     NNKEFFIGQKVYPNFEDYVSQPAGAGICVDLNYLKYYNPISFEESTDLNLINSDPLTT
                     YILVPKKYKEYAKMIEKNYLEDIQFRLEDSPPQAPYKTPNLKNLKIKLIFVNNNQKYF
                     SFNTLYGKAKDNYTITDPIVRVINPEITESLFWGNILTSDGGLFFDQKHTSNQNFFNQ
                     INPYIKEFNLENIINFSYSVFQETGELLSQKKVNKLNAYLQYLLILGLFIIINFQMIF
                     VSFTINSKKIALKKIFGYSPISQVLDLCLLPFTIELFATMCFQLIFSKNTYLYFIIFM
                     IFLINLITSIIIYKKNSFKYFKENIL"
     gene            6795..7415
                     /locus_tag="ACGXWR_002615"
     CDS             6795..7415
                     /locus_tag="ACGXWR_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFK0804098.1"
                     /translation="MILSVENFTLSINKKKIKQNWNFSISEKDFIIVTGKSGSGKTTL
                     LNNLSLIDKQYTGNLFYFEKKVSKHDIQRLRRNHISYLFQNYALLENQTVQYNFELAK
                     KFNSNISNDHIYNLLTDFSLPKDILKEKIFLLSGGEQQRIALIRNMLKPFDILFADEP
                     TGNLDKENSTFIMNFLKNLTEKEKKAVVLVTHDLNVLNYGTNIIEL"
     gene            7529..7666
                     /locus_tag="ACGXWR_002616"
     CDS             7529..7666
                     /locus_tag="ACGXWR_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804099.1"
                     /translation="MILLKKEYEKFYDRLIYSLQLPKKLNRQLQKTYETKSTEEWESY
                     C"
     gene            8108..>8483
                     /gene="mobC"
                     /locus_tag="ACGXWR_002617"
     CDS             8108..>8483
                     /gene="mobC"
                     /locus_tag="ACGXWR_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HFK0804100.1"
                     /translation="MSEQNQNLASNSSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVASG
                     DAQRLSENLKIMQKELQKIWQQL"
BASE COUNT         3238 a         1302 c         1294 g         2649 t
ORIGIN      
        1 gctccctaca cacaagaaag gatacaaact acgattgatt tacaagttaa aaaactccat
       61 caagagctat tagatcagcg aaataaagaa caaaaaaagg cgttcattca acgatcaatg
      121 gattttcttg cccccttatg ttgcttagtc atgacactgt tcgcattttg gttagtatgg
      181 ggaggctaaa atggcatttt atttacccta tctactcatt tttgttagta tttcaggaag
      241 tatttggctc atctataaaa tttttcaaac aagatattca ttaaaaggct ctaaaattcg
      301 atttaagcga tttttcttga ttggctgtat attttccttg ataatcgttt caagcggctt
      361 attcggcgtt ttagagggca ataagcgcgt ttctagaagt attttattag gaaatgtcac
      421 tcaaaagtat gaatcagcac gtgataaaaa gaaaaaagag caagcattag cacaaaaaat
      481 tgaagaattt accgcttgtt atgaagacat gaacgatatt tttgtgaatc aagaaaaacg
      541 tttgacggat aaaaacatgg aaaaactcac tcgtctttat caaaacttgc cagaaaaaca
      601 gcaaaaagag gttcaagaca actatgagcg aaccaaaaaa gacgtgcaat attttaaaga
      661 tacgcagaca gaagaagctt gttataattt attcagtgat acaatccctt tttcaactag
      721 tgaacaggaa cgaaaagaac ggcaacaatc agttacctac gaacgttata aagcactgct
      781 tcagcaagca acgaacatac aaaatccaac gaaaaaagaa acggcattaa attatctaaa
      841 aagtgtcaag gaatggttag atcagcaaca gcaaaattga atttgatcgg caatcatgtt
      901 aaactaaaca tgcaaatgat caaacattag atacacgaaa gccccagaga ggtcggattc
      961 tctggggctt tttttcaggt tgatgtcgcc tttattgatt ttacttcttg tttcggttat
     1021 tcaaccaata actgaataaa gagacacaaa cttctataag aagggggcaa atgaacaatt
     1081 caaacattag atacacctcc ttccagtcgc aagactgtcg gataggcgac aagttattat
     1141 atcttaaaaa attaaacttg tgtggtgttt ttaagtatcg cttattttag ggttgttagg
     1201 gcttgccctg accgcctgta aggcgcttta aagctagata aggattttta tccaagactg
     1261 tcttaaaacg gcttagataa gcattcagaa ccgctcaaag gcctctttac caacatgttt
     1321 ttagcaaagg agcctttagg cgactgcgca gtacaatgtg agagcgtagc gatcacacct
     1381 ttttggcgac cgtaggaagc aaggttttgg attggcagtt ttgaaaaatg cgcgaacctg
     1441 tttaaagaaa aaagaagtgg tttttaggcg ggaaaattag cccccctctt tttatatctc
     1501 tttttaaacc tctttttaaa cctctttacc gtaagctgtg tccttactct accaatggat
     1561 acagaatgtt atgaaggaca ttttgtctgt ttatgaagga cattttgtct gtttatgaag
     1621 gacattttgt ctgtttatga aggacatttt gtctgtttga acgtcaaata tgaatgtctt
     1681 gacatttaaa aaatgtcatt cataattgga ttgaggtgat tatatggcta atgagattgt
     1741 aaaataccac catgaattaa atacaattcc tttaagaaaa tttacaccgg ttgaaatgaa
     1801 tttgtttttt tccatcgtgt ctagaatgcg tgaaaaaggg gataagacag ttcgttttac
     1861 gtttgaccaa ctaaaagatt taagtaacta caaagcaact gcaaatgtac gatttgtaga
     1921 agatttaaaa gcaacttatg aaaaaatctt atctttacgc tttggtcgta gaagtgagtc
     1981 tgggctttct tacgatatgt ttgtaatgtt tacagaattt aaaatcaacg gggacgtaga
     2041 aaatccttac gtagatatac gaatttacga aaaagcactg cctttgttaa ataatttaga
     2101 cgagtgggta cgctattctt tacaacaatt caacgagcta caaagtggct atgcaaagac
     2161 tatgtttcgt ctgttaaagc aatacagaac caaaggtttc gcatatttct ccaaagaaga
     2221 ctttcttgaa ttattagata ttcctaaaag ttataagcaa cctgatatag ataaacgagt
     2281 tataaaacct atacgtcaag aactaactgc aattttcaaa ggactaacaa tcaaaaagaa
     2341 atacggaaaa ggacggggaa aacctgttat tggctatcaa tttacgttca aacctgagat
     2401 caaaaaagca gacgacttta acaaacatgc accaaccaaa gaagaccaaa ataaagcatt
     2461 ggctttagct gataaacaaa aagaatacga agaacccgct acaacaatta acgaaaaaat
     2521 caaacagaag aaacgagaac ttgaactcct ccaacaaatc aaacaactag aaaaagagaa
     2581 aaaagctctt gaaaaacaaa cagagtccgc actttcggaa aaagagaaaa aaagtttatt
     2641 atctgattta gataatttat tccagtagca acctaggagg caaccagtat gcaaccacaa
     2701 gaaaccttta caataaagga attgtcagat ctttttaaga tgagtaggca agcaatatcg
     2761 aaacatatcc aaaaattaga ttcttccatg atagctaaaa atgagcgtgg ttataaggtt
     2821 gtattgcgtt ctggagtatt gcaacttgct cgcaacttag acaatcaaag gttgctagat
     2881 aagttgcata aacatgaaca aaacaacgat aaaaatgctt atataccaaa caaaaacgtg
     2941 gttgcaaaca agttgctaga tcagttgcgt gaagaaaatg aatttttacg agaacaactt
     3001 gccctcaaag agcaaaataa ttctcatata caaaaactac tcgaccagca acaacaactc
     3061 accctgcaag ccaaccaaca aatcgaaaaa cttcaggagc aactgcagtt gacttatacg
     3121 gaagagtctt cagagaatag ttcaacgact ctttctgaag caacagaaac aatggacgaa
     3181 caaacaaaga attggaaaaa atggtggcag ctatggaaat gaagaaggaa atacttatga
     3241 caaaaaaaca cttgctattc ggttctatcc tactaggaat attaagcttt agcccaatgt
     3301 tattatcagt ggccaacaaa ggaaataaaa aaggggaact aaaactcaat cctaattact
     3361 acaacagtca aaatgaggaa gtatttgtag aaaaacttga taaataagaa aagactgctc
     3421 gtacgagcag tctttctgaa agagattatc ctattattaa ccttagaaaa gaataataaa
     3481 tgaatatgag atatgtaaaa agcataacaa acacaaacaa aaataacaag tatttaaaaa
     3541 atgaccgatc aatattcaca aaatcagcgc ctggatccct tggtacaggc gttacttggt
     3601 agtatgtaca ttatgtcaac tatgcaatta aataactaac tacttcatat tagcttaata
     3661 aaataatcaa aataactagg gggaaaaaca ttgtataaaa aaatttttca ttttttaaat
     3721 aagaatagta aatataaaaa taatttaaga tatctattac tattaatcca gatagagcaa
     3781 accaagtaaa tattccatgt gtaaagctaa aaaaattcat ttgaatcaat tcaaataaac
     3841 ctaatatagt aacaaatata ttaaaaataa tagctgtcaa taccagtaaa ttattttgtt
     3901 tattttttaa attatcttca tttaaaatag aatttatgtt agtactataa aattcacaaa
     3961 ttttttttag tgtctctata tctggtgttg ttttgttatt ttcccacttt gaaatagttt
     4021 gacgtgtaac attaaatttt cttgccacat attcttgagt ataccctttt ttcactctta
     4081 attctcttag cttagatcct aaatcctcca ttttttctcc tatgtaaacg attatttaca
     4141 taaaatttta tcataaaaat actaacgcgc caaaaaagtt ctttatttta taaaacacac
     4201 taaaataaaa taattctagt aaaaaagata ggagaaataa gttatgaaaa aatttttatg
     4261 tctttctgct ttaatgggtg tcttattaac tagtggagga atagttagtg ctacagaagc
     4321 tttaaatcta gatgtacccg aagaccatac cgccatttac ggaggaggaa tggaagctac
     4381 agaagaagga ttttcttcta gtaaattgag atatgctgct ggcggcggag atttcaactg
     4441 tggggttaat ggatttaaag tttatgcaaa ttactaccat gctagagcta aacatagtgc
     4501 aacagctaaa aatggacgag gcggtcaagt acgatcagtt cagaaagctg gagtaagagc
     4561 ttatgcaaca tgcaatgcca cacttactgg aaatactggt tggtggaatg tttattaaaa
     4621 aagagagttt aaactctctt ttttatttac atttgaaagg aaattcaaaa tatgttaaaa
     4681 aaaataaacg ctgttttatc actttttgtc tgcattacaa tactattctt ttctactaat
     4741 gttataaatg gtataaagac ttctgaagcg ctatataaaa ataccgctga aattcatatg
     4801 caatataaag atgatatgga ctttaacagt tatataaacg ctttgtatga aatatctaca
     4861 caagaaaata ttaatatttc tcaatatagt tttactgctg ttaaccaact aactattctt
     4921 gctacaaacc ctaacgctaa caaacactgg aaattttcta aaaaaaatat attagcaaga
     4981 aacgattcta aagtccatta tactaataac aaaaattcta agtaccaatt aaaacttcca
     5041 aataattttt taaatataaa tatttatcct ttttctcatg tggaaaatat tggattaagt
     5101 gaaatattat atgtacaagg aaactcaaac aaattaattc ctgtactgaa aaaatatgga
     5161 acacctacta tttccaatat caatcaatca gatacttttc aaattaatac taatattgtt
     5221 cttgttatct gctatcttag tatatttatt gtaattacta caattatatt tgctttttca
     5281 aaaatgaaag aaatcactct aaaaaaaatg ttaggctata actcttttga tactataaaa
     5341 gattctatta aagagttaaa cctcttattt tgttctttga ttataacttt cattttatct
     5401 atttttttga gcatatatta cagtaacgaa aattttttcc tatcatttct tctatgtagt
     5461 atttttcatt ttataattag ttttttattt atcatagtta ctctaagtat ctatcattta
     5521 tctagtataa aaaattatct aaaaaattca cgaccactta agttaaatct ttgtatatta
     5581 aatatctgtc tattcttaag catgatcctt ctgttaatag cttctacaaa agtaataaat
     5641 atccataatg aagccgaaaa taattctctt aaatattggg aaagaactac taatttatat
     5701 aaaacaaata ttactaatca attaaataga aacaacaccg tagaagaaaa taactacttg
     5761 aaaaaagcta gtaaatttgt ttataaaata cagaagaatt ataaaacttt tattatcgcg
     5821 ccatacaatt acgcaactat ccaagaaaat aataaagaat tttttattgg acaaaaagtt
     5881 tatccaaatt ttgaagacta tgttagtcaa cctgctggtg caggaatatg tgttgattta
     5941 aactatctaa aatattacaa tcctatttct tttgaagaat ctactgactt aaatttaata
     6001 aactctgatc cactaactac ttacattcta gtacctaaaa aatataaaga atatgcaaaa
     6061 atgattgaaa aaaattattt agaagacata cagtttagac ttgaagactc tcctcctcaa
     6121 gctccttata aaactcctaa tttgaaaaat ttaaaaataa aactaatatt tgttaataat
     6181 aaccaaaagt attttagttt taatacctta tatggaaagg caaaagataa ctatacaata
     6241 actgatccca tagttagagt tattaatcca gaaataacag aatcattatt ttggggaaat
     6301 atattgacta gtgatggtgg attatttttt gatcagaaac atacttcaaa ccaaaacttt
     6361 tttaatcaaa ttaatccgta tataaaagaa tttaacctag aaaatatcat aaatttttct
     6421 tattctgttt ttcaagaaac tggtgaatta ttatctcaaa aaaaagtaaa taaattaaat
     6481 gcatatctac aatatctttt aatattagga ttatttataa taattaattt tcaaatgatt
     6541 tttgttagtt ttactataaa ttcaaaaaaa atagctttaa aaaaaatatt tggatattca
     6601 ccaataagtc aagttttaga tttatgttta ctccctttta caatagagtt atttgctact
     6661 atgtgttttc aattgatatt ttcaaaaaac acttacttgt attttataat ttttatgatc
     6721 tttttaataa atctaattac ttctattatt atttataaaa aaaatagttt taaatatttt
     6781 aaggagaata ttttatgata ttatcagttg agaatttcac cctgtcaatt aataaaaaaa
     6841 agatcaaaca aaattggaac ttttcaatat cagaaaaaga ttttattata gtaacaggaa
     6901 aaagtggtag tggaaaaact actctgttaa ataatttaag cctaatagat aaacaatata
     6961 ccggtaactt attctatttt gaaaagaaag tttctaaaca tgatatacaa cgtctacgaa
     7021 gaaatcatat tagctattta tttcaaaact atgctcttct tgaaaatcaa acagtacaat
     7081 acaatttcga attagcaaaa aagtttaaca gtaatatttc caatgatcat atttataatt
     7141 tattaacaga tttttctttg ccaaaagata tcttaaaaga aaaaatcttt ctcttaagcg
     7201 gtggagaaca acaaagaata gcattaatta gaaatatgtt aaaaccattt gatatattat
     7261 ttgcagatga acctacagga aatttagata aagaaaactc aacttttata atgaactttc
     7321 tgaaaaattt aacagaaaaa gaaaaaaaag ccgttgtact agtaacacat gacttaaatg
     7381 ttctaaacta tggaactaat attatagaat tataattttt acccgtgatg ctagctgatt
     7441 taaaactagc accacgggta tttattttat attccatctc tcctatccca aaatttaaat
     7501 aatcacttaa taaaaaggag gcacccaagt gattttattg aaaaaagagt atgaaaaatt
     7561 ttatgataga cttatttatt ctttgcaatt gcccaaaaaa ttaaaccgtc aattacaaaa
     7621 gacttatgaa actaaatcaa ctgaagaatg ggagagttat tgctagattt ttggtagaag
     7681 taacaaaaag tggacatatt atcataatga ctcgccgaaa gtctgataaa aaattggcta
     7741 aaaatattgc tgaatgttta ataaaactat cagttttagc taaatagtta gtagtttaca
     7801 caaaaaagca tttatgtttt ttgttgcaaa gcaacaattt catcttcggt gaaataagcg
     7861 aaactttaca aaaagtggct agcatttgct agcttttttt gtattgtgga gcgtgggttt
     7921 tgagggggat tcaaggggga gcttgcgccc ctttgacaag cggttatttg caccaaatac
     7981 ggaggtattt ggctagcaaa tatagagctt gccaaaccct tttagtgagc tttactcatt
     8041 gtaccttttt aggtacaatg gtattgcgaa cgatacgtcc gtaggacgta ctgaaagggt
     8101 gggacttatg agcgaacaaa atcaaaattt ggctagcaat tcttctaaaa aatataccta
     8161 tcgatccgag ccaaaacaaa tcagttttcg agtgagcgaa tccgaatttg caaagctgaa
     8221 gcaatcggct gaagctttgc aaatgagtgt gccggctttc gtgaaagcca aggcacaaaa
     8281 cgcgcgtctg gtgacaccga aagtggcgcc agacattgcc caggcaatcg cgcgcgattt
     8341 agccaaagct ggagggaata tcaatcaaat tgctaagtgg tgcaatacac accaacatga
     8401 cgttgcttct ggtgacgctc aacgtttatc cgaaaaccta aaaatcatgc aaaaggagct
     8461 acaaaagata tggcaacaat taa
//
LOCUS       DAYNVV010000091         8402 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.094, whole genome shotgun sequence.
ACCESSION   DAYNVV010000091 DAYNVV010000000
VERSION     DAYNVV010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8402
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.094"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..770)
                     /locus_tag="ACGXWR_002618"
     CDS             complement(<1..770)
                     /locus_tag="ACGXWR_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
                     /protein_id="HFK0804101.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHFFRKGITMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKVRTLNDKYVAI
                     FMDATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDIYSRG
                     VHDVLLFITDGLKGMKDTIHQIYPKAKYQHCCVHVSRN"
     gene            876..1607
                     /locus_tag="ACGXWR_002619"
     CDS             876..1607
                     /locus_tag="ACGXWR_002619"
                     /inference="COORDINATES: protein motif:HMM:NF019736.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804102.1"
                     /translation="MLSEKEQENFDEYAYFVNTAIDRQSLGKVLGGKMISVVEPYYEW
                     IMDRQQLDPTTSFDMKNVNLVDDMEPYIERKLYIVNAAHAAVAYLGALKGYKTIQEAI
                     QNMEIFNLVKQFLMENIEYFVQKYHFSREELTSFVEKTLNRHGNQKLSDEITRVGSSP
                     IRKLGPNDRLIAPIVKLDSYHLPYDAGIKVIAAGYHYRNLADPEAEQLRRMIVNDGLK
                     ATIKKISRLEGKLLNEVVAAYESQI"
     gene            1619..2050
                     /locus_tag="ACGXWR_002620"
     CDS             1619..2050
                     /locus_tag="ACGXWR_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFK0804103.1"
                     /translation="MLKEQLSGNTMFMDAIDSWQEAIRVSARPLIGKGIIEESYVQAM
                     IQNVLDNGNYIILLPLVAMPHARPEFGSKGVGMSFLCLDKPVMFPSEEPVKFFFTFSS
                     DSPKGHLDLMANLGELLSDEKMYQKLFDVKTEKALLDLIKK"
     gene            2064..3509
                     /locus_tag="ACGXWR_002621"
     CDS             2064..3509
                     /locus_tag="ACGXWR_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HFK0804104.1"
                     /translation="MEVANKKKRVSMRAKVQAIGGFLTNMVLPNIGAFIAWGIVTALF
                     IPTGWFPNESLNELVSPTVSYLLPLLLAYTGGRMVGGTRGAVLGTIGTIGLIIGADIP
                     MFMGAMIMGPLGGWMMKKTDDFLDGKVPAGFEMVVNNFSIGIIGFILMCLSYLVVGPI
                     IQSANQFVTSAIEALVSTGFLPILSLINEPAKVLFLNNVIDQGVYYPLGMQQTLEAGR
                     SIYFMVASNPGPGLGLLLAYSLFGKKAAKQTAPGAIIIHFFGGIHEIYFPYVLMKPLT
                     ILSMIAGGMTGIITFELFDAGLVAGPSPGSIFSYLALTPRGNFLGVMAGVVTATLVSF
                     FVTSVILKADKSTDEDRNFELSVQKSKTMKSEGRKLLKEENAREICTEKKEMNKISFA
                     CDAGMGSSAMGATIFKKKLQKAGITDVEIKNYRIEEVPEDSDLVIVHQDLEERTRKAH
                     PNMKIVTLKNYLQDPVINGLAEEIIGLKTED"
     gene            3795..5420
                     /locus_tag="ACGXWR_002622"
     CDS             3795..5420
                     /locus_tag="ACGXWR_002622"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFK0804105.1"
                     /translation="MKKIYSKEIDCFRGLAVLAVIFYHLPNSLLPGGLQGVTIFFVVS
                     GFLMAKNTIRDEKNRQFSFLHFYYKRIKRIYPFLLFSLVVFIFILGISNIRLIGNIRS
                     ELPSLIFGYNNWWQLNQGVSYFDSYFNASLFKHYWSLSVELQFYLIWPFLFIVIKRMR
                     RKQVFYLIYTLIFVSILFSLFLPSTKAYYHTIAKLFPFLLGVWGYFNRITIGRFFEQN
                     TFSKIWLLLLASLCLILFPIFPYTLNELLISICFALLLASVDDMNIAKKTKIASTKLS
                     FVGKISYELYLVHFPVLIALTNLFKHHHWKYLDIAGLFTVFLCTLLMITCFRKGVQKM
                     RSPKIWTAMALMIIGVSVLVLRAPASRLTADQNQLQSLLKENSSKANAGENLLSQEKK
                     ILFIGDSVMLGAYQELKETFKKEALVDAKESRQITALPEILKEHKDLVSYQQIVIGLG
                     TNGVITDEAIEQTMSLLKDKKVYWVNIKAPTGWQDTINATLATLPNQYSNITMIDWYS
                     ESKNHPEFFYDDETHLNESGRTAYAKYIASVIQ"
     gene            6052..6405
                     /locus_tag="ACGXWR_002623"
     CDS             6052..6405
                     /locus_tag="ACGXWR_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804106.1"
                     /translation="MNSFKKKFVSRFLNMKNFFEKKGDYDAYNYVLNLEKQTYYTLRK
                     NDDNDFWTMLPKMLSIDSKLSLLEEFINLDIEEFCGGKELINMVESDYHTYYKESCGY
                     KVDEQCPQSIIFYIE"
     gene            7186..>8402
                     /locus_tag="ACGXWR_002624"
     CDS             7186..>8402
                     /locus_tag="ACGXWR_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0804107.1"
                     /translation="MQTFLTKTSFKKVVLLDYLLEKDNWCAMEELRNLLNVTEKSVLH
                     YIEELEDLFKQYNGNILLKNEDNKRFFIKKEKDFPIYNIYLHFYKASYNYHLIDFMYK
                     YPRSVLKDFAKEQFTSVSTVFRYAKLLIPYFRRYHITFHPFQLELNASEANIRSFFYY
                     FYWNSTRESSDKWPFHIEQKEIEKYIVAFEGIYDITLTIFQKRVFSFWLAINIERSSF
                     RKVRVDNEYKSVISDDPHFNLLKKWSKQINLSFNSDELCFLYRIIYSFGVIDGNAIYE
                     NSHAYAHQRQNTCSYRAVENLEKVLQSMFRFSLDIKDPELIFNFIAFHERSYLFYGNP
                     DLFFNRSYIEEMKEEEPRTYHIMEKLKKELQANADLDVSKKLENWAQLFLDYYYVLDY
                     YDLFLTNVKPIKI"
BASE COUNT         2898 a         1178 c         1572 g         2754 t
ORIGIN      
        1 atattacggg aaacgtgaac acagcaatgt tggtatttag ctttaggata aatctggtga
       61 atcgtatctt tcatgccttt taagccatcg gtaataaaca gtaagacatc atgaacccct
      121 ctggagtaaa tgtcctgtaa caactcattc caaacgtagg tcgattcagt cggagcaatc
      181 gcataactta gtacttcttt agtgccgtct tctcgtatac caatggcaat atagattgct
      241 tctttggaga cggtttgccg ttttaatgga atataagtag catccatgaa aatagcgaca
      301 tacttatcat ttagagttct aactttaaat gcatttactt cttcagtcag cactttagtc
      361 atgttggaca tggtttgggg cgtgtagtga tgcccataca ttttctcaat caagtctgcg
      421 atttccgaca tggtaatacc ttttcggaag aagtgaatga cggtctcctc taaggtatca
      481 ttcgtccgtc tataagcagg aacagtctgt tgcttgaact cgccgttgcg gtcgcgcgga
      541 atctggagat gaagttcccc gtactcggtc ttgaccgtac ggtcatagga gccgttacga
      601 gaattacccg tgttaaaacc aatgcgatcg tacttttcgt aatcgaggaa agccgttaac
      661 tccgttttga gaagcgtatt gacagctttt tccaaatgga cacggaataa ttcattcaaa
      721 tcgcctttgt tcgctagagt ctttagaatt tctgtagtaa aatcgttcat atggaagtcc
      781 tcttttctgt gaatgtgttg tggtaactct attctacaga agggacttcc ttttttctat
      841 ttacacaaaa tattttacac tctcaaattt attctttgct gtcagaaaaa gaacaagaga
      901 attttgatga atatgcatat tttgtgaata cggcaatcga tcgacaatct ttaggaaaag
      961 ttcttggagg aaaaatgatc tctgttgtcg aaccttatta tgaatggata atggatcgac
     1021 agcagttaga tccaactaca tcttttgata tgaaaaatgt aaatttggtt gatgatatgg
     1081 agccttacat tgagcgaaag ctttatatcg ttaatgctgc tcatgcggca gtagcttatt
     1141 taggcgcact gaaaggatat aagacgattc aagaagcaat ccaaaatatg gagattttca
     1201 atctagtcaa gcaattttta atggagaata tagagtactt tgtacaaaaa tatcattttt
     1261 ctagagaaga attaacatct tttgtggaaa aaacattaaa ccgtcatggg aatcagaaac
     1321 tctccgatga aattactcgt gtaggaagtt cccctattcg aaaattaggc cctaatgatc
     1381 gtttaattgc tcccatagta aaactagatt catatcattt accttacgat gcaggaataa
     1441 aagtaattgc tgcgggatat cattatcgga atcttgctga tccagaagct gaacaactac
     1501 gtcgaatgat tgtaaatgat gggttgaaag caacgattaa aaagatttct cgtttggaag
     1561 gtaagctgct gaatgaagtt gtcgctgctt atgagtccca gatttagagg aggagaatat
     1621 gctaaaagaa caattgtcag gaaatacaat gtttatggat gcgatcgatt catggcaaga
     1681 ggcaatccga gtaagtgcgc gtcctttgat aggaaaggga ataatagagg aaagctatgt
     1741 acaagcgatg atacaaaatg tgttggataa cggaaattat attatattac tgccactagt
     1801 agcaatgcct catgcgcgtc cagaatttgg gagcaaaggg gtcgggatga gctttttatg
     1861 tttagataag ccagtcatgt tcccaagtga agaaccagta aaattcttct ttaccttttc
     1921 ttctgattcg ccaaagggac atttagactt aatggccaat cttggagaat tgctgagtga
     1981 tgaaaaaatg tatcaaaaat tattcgatgt gaagacagaa aaagcattgt tagatttgat
     2041 aaagaagtaa aggagagaag aaaatggagg tagcaaacaa aaaaaaacga gtctccatgc
     2101 gagctaaagt tcaagcgatt ggcggtttct taacaaatat ggtattgcca aatataggcg
     2161 catttattgc atggggaatt gttactgcat tattcattcc aactgggtgg ttcccaaatg
     2221 aatctctgaa tgaactcgta agtccgacag tcagctatct attgccgtta ctacttgcct
     2281 atactggtgg tcggatggtt ggtggtacac gtggagctgt tttaggtaca atcggaacaa
     2341 taggtttgat tattggtgct gacataccaa tgttcatggg agcaatgatt atggggccac
     2401 ttggtgggtg gatgatgaaa aaaacagatg attttttaga tgggaaagtt cctgctggtt
     2461 ttgaaatggt cgtcaataat ttttctatag gaattattgg tttcatactg atgtgccttt
     2521 cttatctggt agttggacca ataatccaat cagctaatca atttgtaacg agtgcaattg
     2581 aagcattagt ttcaactggt tttttaccga tactgtcctt aatcaacgaa ccggcaaaag
     2641 tcttattttt aaataatgtt attgaccaag gtgtttatta tccattaggt atgcaacaaa
     2701 cattagaggc aggcagatca atttatttca tggtagcatc aaatcctggc cctggcttag
     2761 gactattgtt agcttattct ttatttggta aaaaggcagc aaaacagaca gcaccaggtg
     2821 caatcatcat ccattttttc ggcggaatac atgagattta ttttccatat gtattaatga
     2881 aaccactcac tatattatct atgattgctg gtggaatgac aggaatcatc acttttgaat
     2941 tatttgatgc gggcctggta gcaggtccaa gtccaggttc tattttttct tatttagctc
     3001 taacgcctcg gggaaatttt ttgggtgtca tggcgggagt ggtcacagca acactggttt
     3061 ccttttttgt aacatcagta attttaaaag cagataaatc aacagatgaa gacagaaatt
     3121 ttgaactatc agttcaaaaa tcgaaaacga tgaaatcaga aggaagaaaa ttattaaaag
     3181 aagaaaatgc tagagaaata tgtaccgaga aaaaagagat gaataaaatt tcctttgctt
     3241 gtgatgcagg aatgggaagc agcgcaatgg gcgcaacaat attcaagaaa aaattgcaaa
     3301 aagcaggtat tactgatgtt gagataaaaa attatcgaat tgaagaggta ccagaagata
     3361 gtgatttggt gatcgtacat caagatttgg aggaacggac tagaaaagca catcctaaca
     3421 tgaaaattgt gacattaaag aattatttgc aagatccagt aatcaatgga ttagcagaag
     3481 aaatcattgg attaaaaaca gaagactaat ttatgggaat ttttgattaa cctttattaa
     3541 aattattttg cctaatataa aaaggttgtg acatggcttg tgtcgcaacc tttttttgtc
     3601 gcacaaataa ttaatcggat attttatgtt catatttttt gtgatcaacg agaactgatg
     3661 gggcaaagat acattttaga tacttttaac tgttaattta caaaacaagg tgaaacgaat
     3721 agaaaaatga aaaaatcgat acggaagaat atgtttgatt aaaacatgca tgaagagaag
     3781 gaggttgatg atacatgaaa aaaatatatt caaaggaaat cgattgtttt agaggccttg
     3841 ctgttttagc agtgatattt tatcatttgc caaatagttt gctgccaggc ggattgcaag
     3901 gagtaacgat cttttttgtg gtttctggtt ttttaatggc taaaaatacg ataagagatg
     3961 aaaaaaacag acaattcagt tttttacatt tttactataa gcgtatcaaa cgtatttatc
     4021 catttttact gttttctttg gtcgtattca ttttcatact agggattagc aacattcgat
     4081 tgataggaaa cattcgtagt gagctaccca gtttgatttt tggctataac aattggtggc
     4141 agctgaatca aggagtatct tattttgact cttactttaa tgcttcttta tttaaacatt
     4201 attggtcgct ttcagttgaa ctacaattct atttgatatg gccatttttg tttattgtca
     4261 ttaagcgtat gagaagaaaa caagtgtttt acttaatcta tacattgatt tttgtttcta
     4321 ttctttttag tttgttttta ccttcaacta aggcatatta tcatacgata gctaaacttt
     4381 ttccattttt attaggagtt tgggggtatt ttaatcgaat aactattggc cgtttctttg
     4441 aacaaaacac ttttagtaaa atctggcttt tattactagc tagtctttgt ctgattctgt
     4501 tcccgatttt tccttataca ctaaatgaac tactgatcag tatttgtttt gctctattgt
     4561 tagccagtgt cgatgatatg aacattgcaa aaaagaccaa aatcgctagt acaaaacttt
     4621 cttttgtagg aaaaatcagt tatgaacttt atttggtgca tttcccagta ttgattgctc
     4681 tgacaaatct attcaaacat caccattgga aatatttgga tatcgcaggt ctattcactg
     4741 tgtttttatg tacattactc atgattactt gctttagaaa aggagtgcaa aagatgagat
     4801 cacccaaaat ttggacagct atggcactaa tgataatcgg agtttctgta ctggtattac
     4861 gtgctcctgc cagtcgactg accgctgacc aaaatcagtt gcaaagttta ttaaaagaaa
     4921 actctagtaa agcaaatgca ggagaaaatc tgttgtcaca agagaagaaa atattattta
     4981 tcggtgattc tgttatgctg ggggcgtatc aggaactaaa ggagacattt aaaaaagaag
     5041 cattggtaga tgcaaaagaa tcaagacaaa tcactgcgtt accagaaatc ttaaaggagc
     5101 ataaagattt agtttcttac caacaaatag tgatcgggtt aggaaccaat ggtgtgataa
     5161 cagatgaagc tatagaacaa acaatgtctt tgctgaaaga taaaaaagta tactgggtaa
     5221 atataaaagc accaactggc tggcaagata cgataaatgc cacattagct acattgccaa
     5281 atcagtattc taatataacg atgatcgatt ggtatagtga gagcaaaaat catcctgaat
     5341 ttttttatga tgatgaaacc catttgaatg aaagtggacg tacagcttat gcaaagtata
     5401 ttgcttcagt tattcaataa ggtagtgatt acgtgtgtta accttacttt ttcctaatag
     5461 gtgaatcaat ttaaataaaa aatacttcat atgataaacg gtgtttaaga ggaggagctt
     5521 tttaatattc gtggtaaaaa agagatgggc gaggtcgtta actgagagct tcttggaaag
     5581 aaatcgcttt ggatttatcc tctttgttat acagaacatg agcgagacga caatactagg
     5641 atgtatgttc tgatcgaagt tttatggtta caagcagcaa tcagcttaga taaaattaag
     5701 gatcgtagga accaagtaaa gaaggctgtt agtaaagaaa caaacgatca agtatgtttt
     5761 actcttaaga agatgcagtg aataaataat agtaatataa tgctagaagg gactgtgaca
     5821 aaagacgtgt cacagccttt tttgttattt taattatcgt ccagtctttt tttataaatg
     5881 attgcttaag cattaaatat taaaaaatat agagttcaaa attactgcac aattagatga
     5941 aaaatttgaa caacaaaaag tgtattttta tactataata gcttttgaat ttagttactc
     6001 tattcaaaag ttatgctatg gacaagaaaa agaataaata gaggtgagaa aatgaatagt
     6061 ttcaagaaaa aatttgtgag tagattttta aatatgaaaa atttttttga aaaaaaggga
     6121 gattatgatg catataatta tgtattaaat ctagaaaagc aaacatatta tacactacgt
     6181 aaaaacgatg ataatgactt ttggactatg ttacctaaaa tgctttcgat tgactctaag
     6241 ctttcccttt tagaggaatt tattaattta gacattgaag aattttgcgg gggaaaagag
     6301 ttaattaata tggtagagag tgattatcat acctattata aagaaagttg tggatacaaa
     6361 gtggatgagc aatgtccaca atcaattatt ttttacattg agtaatatga actattaagc
     6421 aggaaagcaa ctagaagcta ctgatttagt atttacaaat ataaactata ttgctaacaa
     6481 ttattttcta gaaggaataa aagaactaag aatcaagacg ttatcttgat tcttagttct
     6541 tttaacatgg aaaagatgga taatgcactg ttaattcatg atgcatcatc agaaaagttg
     6601 gaaggagaag atagaaatca ttaaatgatt tctacagatg gtaaatgaaa aaacaaaata
     6661 ttagcaaaaa tttgcctaaa tagatagtaa cactttctaa attaaataca agcgcattca
     6721 taaaatgttt atacaaatat ctatgtgata aaaattggat atgttcacaa taaataggaa
     6781 ttaaaataac gaatttacgt ttgtttttat ttaccaatca aattatctta atgcaggaat
     6841 aaaaaattaa attacatatt gttaatcatt tacatctcca ttaataactc aaaatgaaaa
     6901 gatgttttta tttttattct atatttcaga aaaaaattaa actagattat aataattctt
     6961 catgtaaaaa taaaaacaat tacagctatg atgtttaaga taaaacaatt atgaaatcga
     7021 tatccgttta tatacttatc ataagctaga agcaaataac tagcctatgt atgtaagtga
     7081 gattatattt attaaaaggc ttcttttgtt cgatcagtta tagtcgaacg agagaagttt
     7141 attctttgat taaaataaac aaaagtaact tattgaggtg aaatgatgca aactttttta
     7201 actaaaacat ctttcaaaaa agtagtttta ttagattatt tgttagaaaa agacaattgg
     7261 tgtgcaatgg aagaacttag aaatttactt aatgttacgg agaagtcagt cttacactat
     7321 atagaagaac tagaggattt atttaagcaa tataatggta atatccttct gaaaaatgaa
     7381 gataataaac gatttttcat aaaaaaagag aaagattttc ctatttataa tatttatctt
     7441 catttttata aagcttctta taattatcat ttgattgatt ttatgtataa atatcctaga
     7501 agtgttctaa aagattttgc taaagagcaa tttactagtg tatctactgt tttcagatat
     7561 gcgaagctct taattccata ttttaggcgt tatcatataa catttcatcc atttcagtta
     7621 gaattgaatg catcagaggc aaacattcgt agcttttttt attatttcta ttggaattct
     7681 acacgtgaaa gtagtgataa gtggccattt catatcgaac aaaaggaaat agagaagtat
     7741 atagttgctt ttgaggggat ttatgatatt acgttaacta tttttcaaaa acgtgtattt
     7801 tctttttggt tagccattaa tatagaaaga agttcattta gaaaagtacg agtagataat
     7861 gaatataaat cagttatctc agatgatccg cattttaatc ttttgaagaa gtggtcaaaa
     7921 caaatcaatc tttcttttaa cagcgatgaa ctgtgtttcc tttatcgaat aatttattct
     7981 tttggagtaa ttgatggaaa tgcaatatat gaaaatagtc atgcatatgc acatcagcga
     8041 caaaatactt gttcttatcg agcagttgag aatttggaga aagttttaca aagcatgttc
     8101 cgtttttctt tagatataaa ggatccagaa ctcatattca attttattgc atttcatgaa
     8161 agaagttatc tattttatgg taatccagat ctttttttta atcgttcgta tatcgaagaa
     8221 atgaaagaag aagaacctcg aacttatcac ataatggaaa aactcaaaaa agaattacaa
     8281 gcaaatgcgg atttggatgt atcaaagaaa ttagaaaact gggcacaatt atttttggat
     8341 tattattatg tgttagatta ttatgattta tttttaacaa atgttaaacc gattaagatt
     8401 tt
//
LOCUS       DAYNVV010000092         8385 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.095, whole genome shotgun sequence.
ACCESSION   DAYNVV010000092 DAYNVV010000000
VERSION     DAYNVV010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.095"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(82..1233)
                     /locus_tag="ACGXWR_002625"
     CDS             complement(82..1233)
                     /locus_tag="ACGXWR_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFK0804108.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(1387..1917)
                     /locus_tag="ACGXWR_002626"
     CDS             complement(1387..1917)
                     /locus_tag="ACGXWR_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFK0804109.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(2016..2366)
                     /locus_tag="ACGXWR_002627"
     CDS             complement(2016..2366)
                     /locus_tag="ACGXWR_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HFK0804110.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(2523..4052)
                     /gene="ahpF"
                     /locus_tag="ACGXWR_002628"
     CDS             complement(2523..4052)
                     /gene="ahpF"
                     /locus_tag="ACGXWR_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008785 - alkyl hydroperoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000302 - response to reactive oxygen
                     species [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HFK0804111.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     RTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(4062..4625)
                     /gene="ahpC"
                     /locus_tag="ACGXWR_002629"
     CDS             complement(4062..4625)
                     /gene="ahpC"
                     /locus_tag="ACGXWR_002629"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HFK0804112.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(4769..5431)
                     /locus_tag="ACGXWR_002630"
     CDS             complement(4769..5431)
                     /locus_tag="ACGXWR_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFK0804113.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            5615..7261
                     /locus_tag="ACGXWR_002631"
     CDS             5615..7261
                     /locus_tag="ACGXWR_002631"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFK0804114.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            7252..8334
                     /gene="uxuA"
                     /locus_tag="ACGXWR_002632"
     CDS             7252..8334
                     /gene="uxuA"
                     /locus_tag="ACGXWR_002632"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFK0804115.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
BASE COUNT         2758 a         1610 c         1503 g         2514 t
ORIGIN      
        1 gactgtggcg ttatcgtcac agtccttttt tcaaataaac ggttttcacg atgtctcttt
       61 cacaacttct ttttgattta ctcacacttc ataaactttt tttgtaaaat atttgagaac
      121 aagtggagaa ataagtgtac ttaataaaat cacgataact aaaggtgaat agtactgtgg
      181 ttcgatcaat tgactttgct gtccaatttg taaaatgatc aaagccattt ctccacgcga
      241 aatcatacca gcaccgacca tcaatgaact atgttgagaa aaaccggcaa tctgagcacc
      301 aaaataacct ccaagcaatt tggtcaaaat cgctacaagc gtcaatatag aaataaagag
      361 tagttgttca ctaaagtcag aaaaatcaac ttctaatcct acactgacaa aaaatactgg
      421 tataaatact gcatatccta aagcctctac attgtggtat acttcttctt taacctttgt
      481 ctgactgaca gctatcccag caaaaaaagc accaatgaca gagctaagcc caacaagatc
      541 cgctacgtaa gacattccta aacaaataac tagcgatacg atgataatag aagaatttgc
      601 gtacactttt tctgcaaatg aaagtaggaa aggcgcaatc catttgacta ataagaaaat
      661 aaaaacaaaa taaattagct gttcaatcaa aacaagcggt aaagaagcat tgctagaagc
      721 ttcccccgtt agaaaagata ggctgaaact tagaactaaa acgactaaaa tgtcatctac
      781 cacagaagca cccaaaattg ttgatccttc ttttgtattc actacgttta gttcttttaa
      841 tacttctact gaaatactga cagaagttgc cgcaagaata atcccaaaga aaatcgcttc
      901 atttcccgaa acttggaatg ctttgcctgt caaccagcca aaaacaaccg ggaagatgat
      961 cccaagcaaa gcaacgaaca taccaggtcg gaaatatttt ttcaaaagag ataaatcact
     1021 ttccagacca gctaaaaaca ttaataagat cacaccaatc tccgaaaagt catggactag
     1081 aatatcaggt ttgacccaat tcaatccagc ttggcctagc aaaacaccaa caagtaattg
     1141 tccaatcact gctgggatac ctaatctccg cgagatatgt gagccaatcg ttgttgaaat
     1201 caatatcagg cataaaatac caataaattc cattctcatc attcctttgt ataaaatata
     1261 gcccgaactt agcataacat acattattga aaaaatagga aaatatactc acaaaaaaac
     1321 caacaatcca aaagattttt ttggattgtt ggtttttata cggtctattt taataactaa
     1381 aaatgattaa cgtatagtca tttttcttat tctgatgaaa ttgataatct cctggatgcc
     1441 catgaaaatc aaaataaagc cgaatatttg gaatagaagc atcaaacttt tgaatggatt
     1501 gaacaataag acgaatccgc caatcaacaa cagaatacta ctataaacac tccaactttt
     1561 agcttttgta ttcatgctga agaacaactg gaacaagctg ttgatgataa cagctaatcc
     1621 aagaagaatc ggcaggatag aaacgattgc aggtgcaaaa gcatagacga tcagagctaa
     1681 gatcaggaaa aaaagaccac tgaacagacc gatactccaa gaacctgttt tccttttaaa
     1741 acggtaagcc tcaaaaagat tcaacaaccc aagcaaaaca agataggcgg tgatcagata
     1801 accgataaaa tgaaaaacag cagaagggtt tagcacaatc gcaatcccag aaataatata
     1861 aacagcagct cttaataagg cgtatttttg aatattttgt ttaatcgtct caaacatata
     1921 agaaaacctc ctttgactta ttttaacgtg aactagtcat tttaccaaat taaatgttac
     1981 aaaatgagcg aaggagaaga atatctctgg aaaaatcaac ttctgaggat cttttccatt
     2041 tttttgcctt ttgctagctc atcgatcatt ttatctaaat aacgaatttc tttcatcaag
     2101 ttatcctcga tgtcttctac tcgtacacca caaacaacac ctgtaatcaa ggaacgtgaa
     2161 ggattgggga caggggcttc cgcaaaaaat tgttcgaaag tcacttgttt ttgtagttga
     2221 tattctagtt ctgtttggga ataacccgtc agccaacaaa tgatttcatc tacttcctct
     2281 tttatacgat cttttctctc cgcttttgct acatacatag gataaacgct tgcaaaactt
     2341 gtcgtaaaaa tacgattttg cgccataatc agtcaccttt ctttttttca aattatttac
     2401 tacttatagt atataagaaa aagagaagaa aaagcgatta ttcaaaaaaa caaaaaggat
     2461 tgtgacaaaa ttcttgtcac catccttttt tccgctctct gactttttac aatcttcata
     2521 gctcaagtgc gcatcagata atcgaatgct cctaaagctg cagtagctcc tgaacccatt
     2581 gaaacaatga tttgtttgta tggactatct gtacaatcac cagctgcgaa aacgccgggg
     2641 atattcgttg cgccattttt ctcggtcact atttcatttc ttggattcat ttcgatcgtt
     2701 ctatctagcc aatccgtatt agggagtaag ccgactagaa tgaatactcc tgaaacagct
     2761 agtgtatgca tctccatcgt acggcgatcg atataggaga gagattctac ctgattcgta
     2821 ccgctgattt ctttcgtcgc tgcatgtttg ataacagtga cattcgcaag agagactagt
     2881 ttatcctgta agatttgatc tgcttttaat tctggtaaga attctagaac atatacatgt
     2941 tttgctaacc cagccaaatc gattgctgct tcaacaccag aattaccacc accgataaca
     3001 gcaatctctt ttcctttaaa taaagggccg tcacagtgtg ggcaataagc aattccttta
     3061 tttttaaact ctttttcgcc tggtacattg atagaacgcc agtgcgcacc tgtcgcgatg
     3121 atggcggttt ttgctttaag tgatataccg ttagctaagc caatattaat aaaatgttgc
     3181 tctttattta aggaaacggc ctgttgattc atcataatgt cgatagggta actacgcaca
     3241 tgactttcta cttgctgcat caattttgga ccttctgtgt aagaggtacc aatcatattt
     3301 tcaatcccta gtgtttcaac gacttgtccg ccgaaagaat cagcgacaag tcctgtacgg
     3361 attcctttac gtgctgcata gatagctgca ctactagctg ctggtccacc gccaatcact
     3421 aatacatcat aaggttcttt ttcaaacaac tcttcttcaa tcaaagggcc agtgattttt
     3481 tcaacaattt gttcgatcgt catgcgtccg ctactaaatt cttctccatt taaaaacaca
     3541 gttggcactg ccatgatttt tttatcatcg atttcttttt ggaacatccc accttcaatc
     3601 atcgtatgag taatatttgg atttaataca gctaatatat tcaatgcctg tacaacgtcg
     3661 gggcaattat gacaagtcaa gctaacataa ctgtcaaaat gcaatgtttg tgttattttt
     3721 ttgattttaa gactcaaaga ttcactgatt ttcggtgccc gtccactaat ttgtaacata
     3781 gccagtaaaa aagaggaaaa ttcatgaccg agggggatac cagcaaaaac gattccactt
     3841 tctttgccaa ctggattgat agaaaaacta ggtgtgcgca tcgaatctct tttttcccaa
     3901 gagattttag gagacatttc tgctatttcc ttcgtaaatt cagctagttt ttgactattt
     3961 tcactattat ccaaactaac agaaaaaaca ataggagatt caatcagtgc taaatattgt
     4021 tcgagatttt gtttagtttc tttgtctaac atatccacca cctaaatctt tccaacaaga
     4081 tcaaaacttg gtttcaatgt ttcgccactt tctttccatt ttgccggaca aacttcacct
     4141 gggtgggtac gtacatattg agcagcgcga atcttatcaa tcagtgcact agcgtcacga
     4201 ccgattccat ctgcattgat ttccatagct tgaacgattc cgtctggatc aataataaat
     4261 gttcctcgct gagctaatcc ttgttcttca tccaaaacat caaaaatacg agaaatctga
     4321 tgagacggat caccgatcat cacgtattcg attttaccga tagcatctga tgtatcatgc
     4381 catgctttgt gagtaaagtg ggtatcggta gagcaagaaa agacttcaac acctaaagat
     4441 ttcaatgtac tgtattgttc ttgtaagtct tctaattcag taggacaaac aaaagtaaaa
     4501 tcagctggat agaagcaaag aatactccag ttccccataa gatctttttc actgacttct
     4561 aaaaattctc cttgatgata agcatgtgca ttaaattctt cgattttttt cccaatcaat
     4621 gacatagtaa aacctccaat aataattatt tatttataat tattgtaatt tagttggagt
     4681 tgcaaagtca atggatattt tgttatttaa taaagattac tcaaaaacga aggttaatta
     4741 taaaaataga agaggtcgca agaaaatgct actgctggaa atactcggga taacgttgag
     4801 taacagtttc ctgttctttc agcatcatgt gtaagtgcaa tcccgtttga aatcgagctt
     4861 cttctggttt tttatcaact aaagccttga gtaaatcata atgttgttcc atgatcgttt
     4921 cccatggaag cccctgaatg gtcactcgta accagcggaa acgttctaaa tgggtattat
     4981 ggtcatctaa ccagttccaa acttcttttc ttcctgcaat ttcgaaacaa gcttcatgaa
     5041 ataaattatc tgcacggaaa aaagcgcgtt cgtcatttat tttgactgct ttttcttgtt
     5101 cttctaaaat cgtttctagc actattcgtg tttgtgtgtc caatttggaa caacattcaa
     5161 tcatgatttg ctcttccaac tgttctcgga caaagcgagc attttctgca gaaacaagat
     5221 taatttttga aacatacgta ccactttgag gtatcgtata cacgagttct tgctgacgta
     5281 gttgaatcaa tgcttcgcga atgggagtcc ggccgatagc aagatgttcc tccagtgcct
     5341 tttcagatat tttccttcca ggttctaagt cagcatagat aatttgttta cgaatcgctt
     5401 gataagcttg agattgcaag ctgcttttca tctttattcc tccaaaatca tttctatgaa
     5461 cgtagtataa cagaagaggt ctgaaaaaca atctggtatg tcacattaac tagtaaattt
     5521 gtataaatag taaaattttg gttgacatag cgatttttat tgcataaaat tcacttgaat
     5581 acaaaaacta atatgttagt ttaggagggg aaaaatgatt gatttaaaca actggaggaa
     5641 ctttatccct gaattatctc aaaaagaagt agaaatacct cattttgacc gtgcatcatt
     5701 aagagaaaat ggacaaaaaa atcctgtctg gatccatttc ggtggcggaa atctttatcg
     5761 aggatttcat gcagaaatcg ctcaacgttt agcggatcta ggcgaattgt ccactggtgt
     5821 cattgtttgt gaaacattcg atgaagaaat aattgaaagg gcttaccaag attttgatga
     5881 tttgattctt gaagtggtca tgccaagcag tggagagttc gtcaaacgta tattagctgc
     5941 gacagctgac agtctgtatt gtcatccaga ttgttctgaa cactttgata agatgattcg
     6001 acactttgaa aatcctagtt tacaattagt tacttttgct attactgaaa aaggttatcg
     6061 attgaaagat acaaataata aatatatagg accgattgca gtcgatataa aaaatggtcc
     6121 aaagaagcca tcacatacaa tgagtattct tgctgcgcta ctttataaac gttttttatc
     6181 tggagcttgg ccgattgcac ttgtctctac agataatttt tcacaaaacg gtagtcaatt
     6241 acgtacttct ttgctaacga tcgcaaaaga atggcaaaag gaaggttatg tacaaaatac
     6301 atttatccaa tacttatcga atgaagaaat tgttgcgttt ccatggacga tgattgatcg
     6361 tatcaccccg aatccttcct tgtcagttag caaaatgttg gcaaaagagg gcttttcaaa
     6421 tatgtcgatt ttccaaaccg caaaaggaaa taatattgct ccatttgtca atacagagga
     6481 catccattat ttaatcatgg aagatcattt tcccaatgga cgtccgaaat tcgaaaaagc
     6541 tggagtattc ttgactgatc gtgcaacggt agataaagca gatacgatga aggtgacgac
     6601 ttgccttaat cctttgcata cgtctttagc tattatgggt tgtttactgg ggtataggag
     6661 catagctgag gagatgaaag atccagattt atcgctgcta gtttctgaaa tcgggtacaa
     6721 tgaaggcctc ccagttgtgg agtctccagg tatcattgat ccaaagatct ttctggaaga
     6781 agtaattact gtgcgctttt ctaatccaaa tattcctgat atgcctcagc gaatcgccac
     6841 ggatacctct caaaaggtgg cgattcgtta tggtgagacg attaaaaaat atatggaaat
     6901 agaagttaaa gacccgcaga cacttgtatt cataccattg actctcgctg cttggcttcg
     6961 ataccttatt ggcattgatg atcaaggaaa accattcatc ccgagtccag acccactatt
     7021 gacagacttt cagcataagc tttccgatat tcaactgggt acgcaagata catcacatat
     7081 tcatgagaaa atggctccta ttttgtcaaa taaagaaatt tttggtgtag atctttacca
     7141 agcagagctt ggcagaaaaa tagaagaaat gttcatcaag atggtagcag gaccgaatgc
     7201 cgtacgaaaa acattacagg attacttaca agaacatgga ggaaatttat catggaaatg
     7261 acttttagat ggtacggatc acaggaagaa aagattacct tagatgaaat cagacagatt
     7321 cctgcggtca aagggattgt aggcacattg atggatatac cagtaggaga ggtatggcct
     7381 agggagagga tcaaagaact aaaagaagaa attgagtctc gtgggttaac actaaaagta
     7441 attgaaagcg tcaatgtgca tgatgccatt aaaattggat taccttcccg tgagcagtat
     7501 atcgaaaact ataagcagac aatccgaaac ttggcagaat atggaataga agtcatctgc
     7561 tataatttta tgcctgtatt tgactgggtg aaatctgacc ttgactaccg cttagaagac
     7621 ggctcatcca cgttagcttt tatatctgat gatattccag atgatccaag agaaatcgtc
     7681 gcgcgcatcg aacattccag caatgaattt gaattgccgg gatgggaacc tgagcgctta
     7741 gctcatatca aatccttgct tgaagcctat gcatcagtag acgaagaaaa acttcgagaa
     7801 aattttgcct attttctcca atcaatcatc ccaacatgtg aagaggtagg ggtcaaaatg
     7861 gctgtacatc cagatgatcc gccatactcg atttttggat tacctcgaat cgtaaagaat
     7921 cgagaagatt tagattggtt gtgccgcata gtagacagcc cttataacgg aatcactctt
     7981 tgtacaggga gtattgcaga agatccagaa aatgatgtat atgggatttt agcagaattt
     8041 tgtcaaagag atcgaatccc atttgcacat gttcgaaata ttaaattttt agctaatcga
     8101 gatttctatg aggcaccgca taaatccgaa tacggttcat tagacatgta ccgcatacta
     8161 aaaacaatgt atgacaacgg atttaacgga tacatccgtc ctgatcatgg aagaatgatc
     8221 tggaatgaga caggaagacc aggatacggc ttatatgatc gagcattagg tgctgtttat
     8281 ctaaatggat tatgggaagc aatcgaaaaa ggaaacaaaa gtaaagataa ttagtgaaaa
     8341 aaactgtaat tttattatgt aaataagaag gatgttcaaa ttctt
//
LOCUS       DAYNVV010000093         8229 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.096, whole genome shotgun sequence.
ACCESSION   DAYNVV010000093 DAYNVV010000000
VERSION     DAYNVV010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.096"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            328..1251
                     /gene="truB"
                     /locus_tag="ACGXWR_002633"
     CDS             328..1251
                     /gene="truB"
                     /locus_tag="ACGXWR_002633"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HFK0804116.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVNNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1255..2196
                     /gene="ribF"
                     /locus_tag="ACGXWR_002634"
     CDS             1255..2196
                     /gene="ribF"
                     /locus_tag="ACGXWR_002634"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006747 - FAD biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009398 - FMN biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HFK0804117.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2591..3376
                     /locus_tag="ACGXWR_002635"
     CDS             2591..3376
                     /locus_tag="ACGXWR_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFK0804118.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3389..4240
                     /locus_tag="ACGXWR_002636"
     CDS             3389..4240
                     /locus_tag="ACGXWR_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFK0804119.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4364..4816)
                     /locus_tag="ACGXWR_002637"
     CDS             complement(4364..4816)
                     /locus_tag="ACGXWR_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0804120.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(5281..5649)
                     /locus_tag="ACGXWR_002638"
     CDS             complement(5281..5649)
                     /locus_tag="ACGXWR_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HFK0804121.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5799..6281
                     /locus_tag="ACGXWR_002639"
     CDS             5799..6281
                     /locus_tag="ACGXWR_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HFK0804122.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6318..7328
                     /locus_tag="ACGXWR_002640"
     CDS             6318..7328
                     /locus_tag="ACGXWR_002640"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HFK0804123.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7443..8156)
                     /locus_tag="ACGXWR_002641"
     CDS             complement(7443..8156)
                     /locus_tag="ACGXWR_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804124.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
BASE COUNT         2783 a         1337 c         1667 g         2442 t
ORIGIN      
        1 ttaagaaact gaaaaaataa ataaaaaaaa acggaaaaaa gactggaaga atggacagtc
       61 ttttttttcg tttttgggaa gtgaaaacca aactatttac ctgtaagcca cccataaatc
      121 caatcaaatg gtgcaaagaa aaaatcttcc attctattcc ctcctttaaa aaaaacataa
      181 catgatttct atttacgtga gcatgaattt tgttacgttt ttattgccga aaaataaaaa
      241 ccgttcatta tgatgtcaaa ttcgtcagta attgatgcaa tgtgttataa taattcagtt
      301 aaatcaaaaa tgaaatggag aaaagacatg gacgggttat taactttatg gaaagaacgc
      361 ggaatgacaa gtcatgattg cgtattcaaa ttaagaaaaa tcttacatac gaaaaaaatc
      421 ggacatgggg gtacgcttga cccagacgta gacggtgtgt tgcccatttg tattggaaaa
      481 gccacaaaag ttatcgaata tttgacagat tctgggaaaa tctatgtagg cgagataact
      541 ctaggtttca gtacaacgac ggaagatcga tccggagaac gggtagaaac aaaaccagta
      601 gatatgtctt tatctgaaga aaaaatagat gaagtgatgg cttcatttat tggtgagatc
      661 acccagatac caccaatgta ctcagcggta aaagtcaacg gtaagcggtt atatgaatat
      721 gcccgcaata atgaaacagt ggagcgtcct gttagaaagg ctcagattta ccgttttatc
      781 cggacaagtg aattgacaag agacgaagtg acaggaacca tttcttggcg cttcgaagta
      841 gaatgcggga aaggaaccta tgtccgcaca ttagctgtag atacaggcaa gaaacttggt
      901 taccctgcgc acatgtctga tctgacccga acagcaagtg ccggtatgtc ccagaaagat
      961 gctctgacat tagaagaagt agctcaagct gtgaataatg ggacaatcga tgattgtttg
     1021 ctgccaatag aaaaaggagt gaaacgattc aaacgagtag atattactga tgaagtatgg
     1081 cagaaagtaa aaaacggtat gagacttaat tatactgtat ttgcgctccc agaaatgccg
     1141 tcagaagaaa ttgctttgtt ttataaaggc aaagttgtca gtatctatca gccaaacccg
     1201 aaagaaaaaa acaaattaaa acctagtaaa gtattgagaa atgaggaata acgaatgaat
     1261 atcatcaaga tcagacatcc ttaccaatca gaacaaattc cagaagacga tgtcgtttta
     1321 gtactaggat tttttgacgg cgtgcatatt ggacaccaga aagtcataaa gacaggtatg
     1381 gaaattgcac aaaaagaagg attgaaatta gcattgatga ctttcaatca gcatccatcg
     1441 attgtcttta aaaagatcga tcctagcagc gtgaaatatt tgactagcct taagcaaaaa
     1501 gaagaaaaaa tggccgcttt gggtatagat tatttatatg aagttgattt tacttcttct
     1561 tttgctcatt tagcaccgca ggaatttgtt gatcaataca tcgtagggtt acatgcaaaa
     1621 tatgctgttt ccggttttga ttatacgtat ggaccaaaag acattgcaga tgtcgctcat
     1681 tttcctgaat atgccaaagg aagattcaaa atcgtcacag tttctaaaga agaagaacaa
     1741 ggtgaaaaaa tcagctctac ccgtattcga ggattactag acagcggaca agtaaaagaa
     1801 gcagcaaaac tattaggttg cacatatgag gtagaagggg tagttgtcca tggcgatgca
     1861 cgaggcagac tactaggatt ccctacagca aatgtcaaag taaagagcac agttcatttg
     1921 cctaaagaag gtgtttatgt atcggaaata aaaattgggg aaatttggta tccagccatg
     1981 ggttcaattg gacataatga tacattcggt gaaggacggg agctgactgt agaattgtat
     2041 attttggact ttaatcaaga tatctatggt gaacatgtcg cagtacgctg gaatcaattt
     2101 ttaagagatc aagtgaaatt ttctagtgta gaggaattga ttgaacaact caaagaggat
     2161 gaacaagcaa cagctgaata tttttctcag caataaaaca ttatgcataa aatctcttgt
     2221 ttatgtataa ctagcaattt caataaaatg ggtgataaat aagcccagga aaggggctgt
     2281 gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa gtagcttctt
     2341 cggaaataag ccgaaatttc acaaaaattt gagaagtaat ttttgtaaat tacttcttat
     2401 ttcttgaagc tggccacttc tgtcacaacc tctttcttta tagaaataaa aggacactag
     2461 caattcatga aaacgattgc taaagcgtat catttgcttt agactatata tcttggtgta
     2521 cactcacttt aagacggaaa taaaagttat ccgtaataac aggtttaggt atgaaaaagg
     2581 agtgggtact atgtataagg aattagaaaa caaagtcgca gtagtaactg gtggctcaaa
     2641 ggggattgga acagcgattg ctcaacgatt cgggaaagaa aaaatgaatg tagttgtcaa
     2701 ctataactcg gataaagaag gagcagaaaa agcagtcaaa gcaatcgaag aggcaggcgg
     2761 aaaagcagtc tctgtacaag cagatgtcag ttctgaagaa ggaatacagc gtttacttga
     2821 tacggcttta gaaaattttg ggacactgga cgtttggatt aataatgctg ggatggaaaa
     2881 tcagcatcca acccatgaac ttagccttga agattgggaa agagtattaa aagtcaattt
     2941 gactggcgtt tttatcggaa cgaaagcggc tttaaattac tttacagaga atgataaaaa
     3001 aggaaatatc atcaatatgt cttctgttca tgaacaaatc ccatggccaa cgtttgctca
     3061 ttacgctgct tcaaaaggcg gagtaaaact attcaccgaa acggtagcaa tggagtacgc
     3121 accaaaggga atcagaatca atagtatagg acctggtgct atccgtacac ctattaatgc
     3181 ggcaaaattt gatgatcctg aacaaaaaga actcttggaa agtatgatcc cactaggacg
     3241 cgtaggtgaa ccaaaagaaa tagcggcgac agctgcatgg ttggcttcag acgaatccag
     3301 ttatgttaca ggtattacac tatttgcaga tggtgggatg actttatatc cttctttcca
     3361 aggtggaaaa ggataagggt gaataaaaat gggtttattg attgcattga tcccggcagt
     3421 tgggtggggg atccagccac tgattttgaa aaagattggt ggcagaccaa caaatgagat
     3481 attaggaact ggtattggag ccgtgctcgt tggcttactt gttcaattat tcgcttctcc
     3541 agctggtatt tcagtgacta catttttgat tagtttactt tctggtgcat tctgggtcat
     3601 cggacaaaca ggacagtata catctttcaa cttgattggt gtttctaaaa cgatgccaat
     3661 ttcgactgca ttacagttag tcggaacctc attgattggt gtcttcgctt ttggagaatg
     3721 gtctggaagt atgggaaaaa tcattggtgc agcagcaatc attcttcttg tatttggttc
     3781 tgctttaacg gcaatcagtg atgatcctgg aaaaaaaggc ggtatcacaa aaggaatcag
     3841 tctattagca tcaacaagta ttggttattg ggtttacagt gcattgccca aactagttga
     3901 tgcaagcgga ctttccattt tctttccgca aatgatcggt gtctttttag gggcagtgat
     3961 ttatgtgatt ttccgaaaac caaccgcatt ttctgaagac aagagttgga aagcaacaat
     4021 agttggagcc atcttcagtg tgtcagcatt ggcttatatt ttttcagcaa atgaaaatgg
     4081 ggttgctact gcatatatca ttacacagct aaacgtagtt atctctacat taggcggtat
     4141 gtacatcctg catgaaaata agacaccaaa agaaaaaaaa ttaacgatta tcggattatt
     4201 gctgatcgta gtaggaagca tggtcacggt ctttatttga ggataaagat ggtaaaatct
     4261 catttattaa aaaaatattt gtttgaacca aacagtaagt acttataaaa aaatagcgct
     4321 agaatttcca acatctctgg aatttctagc gctttttaat tgtttaagat acaagtgaaa
     4381 tatctgtctg catcaataat ttttcattga tccattgact aaaatttacg acatgattga
     4441 agttaccacc gattagtatc tccgcatgat tgtctttata aagatcgtat tgtaaaagac
     4501 ggtctttttt atttgcgtaa acatcgttat ggtactggac taattgttct cggatttgat
     4561 tgattgctgt aaaatcacga tactgaaggt tgaaacgcat cgtgattggt gcatttagca
     4621 tgaatcgctg catttctttt gctgcttcct ctgcttgatc tccgtatagg aactcaaaaa
     4681 gattacgttc agaaaatttc cattgcccgc caacctttgt tccttttagt tttccttcat
     4741 gaagataatt tctgatagaa cgtgtagtaa cacctaattg ttcggctaat tcatttactg
     4801 agtaaaaatc tttcaatgtt caccctccta tgtgaatggt tctactgact tagttgatat
     4861 ttgcttaatc acgaaatgta gaaagaacga ttttaattaa ggtcattgta aaaatcaagt
     4921 cagaaaattc taacttttct ttctctaaag aaattcgttc tctcctaaag tgatattata
     4981 tttaaatata cctgaaaata atgggcagta ttatgaaaga tcactgatat tttctcgtat
     5041 tttttcctta ttcaaaagtt ttgcaggaaa attgctgaaa aaataatttt actaagtgga
     5101 aaattcaaag ccattcaatc agtgattttt ttcagcacaa gaaagactcc ttataaaaat
     5161 agcagatact ttgtcaatta agtgtttaac cagggatgat aaaaaggata ggattgaaca
     5221 aaacctgtat aagctgatga atagtttcct cgccagtaaa aggtttattc gtataaagct
     5281 ttatcgccaa aatttatcat gacctttttt atcttcaata ttaaatgaaa tcaattgttc
     5341 aatcaattcc cagttgatta cacttttcca aggaactttg atgacgttat ccgtatatac
     5401 gtagcctgct tcttggatat ttttttcaag ggcacgaatc gctgcttttt ccggtgcgat
     5461 agaaaaatga tttttagcaa aactaaatgc aataataaag gtaccatggt cagtaaacat
     5521 aggttggttc cattttacag ttgtgtctag ctggggatac gtttctgtta tcttagcaaa
     5581 aaggtctttg atcttttgtt gatgttcttt ttctttgatc tgattgatga tcggctgaaa
     5641 tttttccatt ctaaaacgcc tccattaagt ggtttgattt attttaccag aaaaacaata
     5701 gttatgtata aaaaacgaac aaaacacaag taatgttgta accgctatat ttatatgata
     5761 agatgtctca aataataaaa tagaaaagag acataaaaat gattgacttg gcaaagaaat
     5821 tcttacacga aaatatatat tttgagttgt atcatcatcg agccatttat acaaatgaag
     5881 atgctttggt aataaagaaa gaacaaggat ttacaggtac agagaccaaa agcttattct
     5941 taaaagataa aaaagataat aactacgtat atctgacttt tactacgaaa caaacggatt
     6001 tcaaagcatt agggaagatc gtcggtaaaa ggctttctat tgtttcatca gaacgcatgg
     6061 aagaacaaac gggacaaaag cagggcgctg tttctccgtt tggttatgaa aaacagattc
     6121 cgattattat tgatgaagag ctcttatcaa atgaaaaact tgtttttgca ccaggtagac
     6181 cagatcaaac gatggtcatc caaacggttg acttaaacaa aatcatccag ctacttgaga
     6241 tgccgatatt tttgatgccg gcaaacgaaa aaaacaatta accaagtaaa atagtgcata
     6301 cttggaggtg aagcaacatg ataagttatc cattattaga aagaaatgca acgattgggg
     6361 ttactgcacc atcctcaggc gtatcagagg aacaccattc gttactcgaa tcagctttaa
     6421 agagaatgga agaaaaatct ttccaagtag ttactggaaa gacgctttgg acgcaagata
     6481 aggaaaaatc aggtccagca agaaaacgag cagatgaatt caatcaaatg atgcaagatg
     6541 aaaatatcca aatgatcttt ccgccttggg gaggagaatt attgattgag attctcgatt
     6601 ttgtcgattt tgatgctcta caaccaaaat ggatagtagg ttattcagat attagtacgt
     6661 tgctacttgc tgtcacatta aaaacaggga tagccactgc acatggaacc aaccttattg
     6721 atttaagagg agagtacttg gatgaaacga cagcaatgtg ggaaagtgta ctgaaaacaa
     6781 gagaaggaga atcgattcta cagcaacctt ctgaaaagta tcaaaaagag tggccccatg
     6841 agcattcatc atcttctgtt ttccatctca ctgaaccaac aaattggcaa tcagtcagcg
     6901 gagatgcagt aaggatgaag ggacgattat taggtggctg tattgatacg atcagtcatt
     6961 taatcggtac cccttatgga gatgtccaat cttttaaaag aaagtataat gatggaaagc
     7021 cgatcttgtg gtttctagaa aattgtgagc tatcgtcagt tgatttaaga agatcacttg
     7081 ttcagatgaa actggcagga tggtttgatg gcagctcggg gatcatgttc ggtagaagtg
     7141 cagcagagga tttgttagat tataaaatga aggatgtata tgaagatctg tcaaaggaat
     7201 taaaactacc gatcttgtat gatattgatt gtggtcatgt accgccacaa ctgacattga
     7261 tcaatggtgc ctatgcagaa gtagcggtag aagatagaaa agcgactgtt ttgcaaacgt
     7321 ttatttaaaa aattttttcc tgccttggag tttatcaaag accaacaaat ctaaatagaa
     7381 aagaaaatga aagaagctga cagtattttg ccagcttctt tttgtatgat ctattagaaa
     7441 ttttaattat ccataactat cacattgatc agctgtttca catcatttgg attacctgta
     7501 ggaatagcta ctacagatgc attatcaata atttcttgag ttgtttctct aatgaacgct
     7561 ggataagatg tttgatctgc aggcatttgc caatgtgaag gaactggata actagtgatt
     7621 gtcccgtcat ggttacttga atacactaaa actccctggt aactgtattt cccagtgagc
     7681 ataaccacat ctttcggata gactgcactc cctgcatcat aaggggcgat aggtgttcct
     7741 gcaggataat gaataacatg tagttcgaaa tcacccgatg tatctctaaa agtattacct
     7801 ctaattgcta gccaaacacg tgcgtactca atttgtagat cagaatatcc tgctaacgga
     7861 tctattgact gagaagactg tgaggaagtt gtgtctattg ttgaagaaga aatatttgtc
     7921 tcaactgtac tactagatgt agaagaagta ttgggctctg agactttact gcttgttgaa
     7981 gatgtattcg tttcagtaga agctgatttc tgagtacttg atttttcagc tgaactggtt
     8041 tgtttgattg aacttttgtc tgtggtcgca gatggatcac tattttcttt actaggagac
     8101 gtacatccta caaggaataa agagaccaac aataaaataa aacctaactt tttcatataa
     8161 aatacctcat tattttttta ataccagtat agcataatcc tgaatttttg aatccgtaaa
     8221 accttgtct
//
LOCUS       DAYNVV010000094         8067 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.097, whole genome shotgun sequence.
ACCESSION   DAYNVV010000094 DAYNVV010000000
VERSION     DAYNVV010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.097"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..884
                     /locus_tag="ACGXWR_002642"
     CDS             <1..884
                     /locus_tag="ACGXWR_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HFK0804125.1"
                     /translation="ISVPVALFSFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTY
                     NDYFQIGMIGMIVSLVVVLTVANISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVL
                     GVVLLDLQIILGFILAGIWALLFTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMT
                     LAMFNNSAAYASPYFSAIFGDWIPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILA
                     VVLAVNPTMSPAFLFPLFAITTIAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGW
                     IIGAILCLITFLLYGNA"
     gene            932..3061
                     /locus_tag="ACGXWR_002643"
     CDS             932..3061
                     /locus_tag="ACGXWR_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HFK0804126.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKNLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKAIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPHTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            3036..3725
                     /locus_tag="ACGXWR_002644"
     CDS             3036..3725
                     /locus_tag="ACGXWR_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804127.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKEIE
                     KRCTEYDLDYK"
     gene            complement(4133..4818)
                     /locus_tag="ACGXWR_002645"
                     /pseudo
     CDS             complement(4133..4818)
                     /locus_tag="ACGXWR_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(4954..5148)
                     /locus_tag="ACGXWR_002646"
     CDS             complement(4954..5148)
                     /locus_tag="ACGXWR_002646"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804128.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(5198..5638)
                     /locus_tag="ACGXWR_002647"
     CDS             complement(5198..5638)
                     /locus_tag="ACGXWR_002647"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HFK0804129.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELEQLFQAYASLDDVNS"
     gene            complement(5642..6487)
                     /locus_tag="ACGXWR_002648"
     CDS             complement(5642..6487)
                     /locus_tag="ACGXWR_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HFK0804130.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVDWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLVANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAVYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            6636..8054
                     /gene="pepV"
                     /locus_tag="ACGXWR_002649"
     CDS             6636..8054
                     /gene="pepV"
                     /locus_tag="ACGXWR_002649"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HFK0804131.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
BASE COUNT         2480 a         1515 c         1714 g         2358 t
ORIGIN      
        1 gtatttcagt accggttgca ctgttctcat ttatgggctc gattatggct ggaatctttg
       61 ctaatatcgt caatttcaaa caatatcaaa cgatttatgc tggtttcaat ccagcggctg
      121 aaagctatac ttataatgac tatttccaaa ttggtatgat tgggatgatt gtaagcttag
      181 ttgtggtact aacggtcgct aatatatcaa tgaacaaaaa gaaacgctat gcaatggcag
      241 caaacgtacc agctgaaggt ggcgacgcac caatgatctc atggttagcc gtattattac
      301 cagttttagg ggtcgttctt ttagatcttc aaatcatctt aggttttatt ctagcaggta
      361 tctgggcatt gctgtttact ggaaaattgc gcggaggtta taaagaaatc tgtcgtcagt
      421 ttgcgaaatt atttacagat ggcgcagtcg atgttgcacc aatggttggt ttcttgatga
      481 ccttagcgat gttcaataat tcagctgcgt atgcttctcc ttatttttca gctatttttg
      541 gagattggat accgcaatca ccattagtct tggcaatcgt atttgctata ttgacaccac
      601 taggattttt ccgcggtcca atgaatctag tcggttcagg ctcagctatt ttagctgtcg
      661 tgttagctgt taatccaacg atgtcgccag cctttttgtt cccgttattt gcaattacaa
      721 cgattgctcc tcagcattta gatattacac aatcttgggt tgcttgggga ttaggttata
      781 caaaagtaac ttctcgagaa tatatgaaga aatccatccc aactggttgg atcatcggtg
      841 cgatcttatg cctgatcacg ttcttattgt acgggaacgc ctagtaaaca aaacgtcgat
      901 aaaaacgatt agataaatgg aggaaaagaa aatgaaacgt tttgtgcgaa tgggaattga
      961 tgttggcggt acacatacga aagcagtcgc aatcgataat gcgacgcacg aaatcatcgg
     1021 aaaatcttca gtgaaaacaa cccacgatga tgtccgtgga gtagctgcag gtgtcgttca
     1081 gtcttttcaa aattgtttgc gggaaaataa tatcagtcca gaagatgttg tgtttgttgc
     1141 acattctacc acacaagcga ctaatgcact gattgaagga gacgtagcaa aagtcggcgt
     1201 aatcgggatg gcaaaaggtg gattagaagg ttttttagca aaacgacaaa ctagattgaa
     1261 cgatatcgat ttagggaata agaaaaaaat agagattgtc aatgcattct tacctgtcaa
     1321 aaacttaaat gtagaccgtg tttcagaaac gatttcttct ttagaaagag aaagagcgga
     1381 ggtcttggtt tcttctatgg catttggagt agataatggg gaaccagaac gagttgttta
     1441 tgaagcagca tctgtgaaag cgatccctac aacgatggct tctgacatca caaaattata
     1501 tggattgaca agaagaactc ggacagcagc aatcaacgca tctattttac caaaaatgct
     1561 agatacggca acctcgacag aagactccgt acgagaagca ggggtcaatg tttctttgat
     1621 gattatgcgc ggagacggcg gagtaatgga aatcaatgaa atgaaaaaac gacctgtttt
     1681 aaccatgctt tccggtcctg ctgcatcagt catgggctct ttgatgtact tgagagcgtc
     1741 taatggtgtt tattttgaag taggcggaac aacaaccaat atcggggtca ttaaaaatgg
     1801 acgtccagca atcgattatt caattgtagg tggccaccca acatatatct cttcattaga
     1861 tgttcgggtt ctaggtgtgg caggcggttc gatggtacgg gctaatcagt caggaatcat
     1921 cgatgtcggt ccacgttctg cacatattgc cggtctagat tatgcagtat ttacggagac
     1981 agaaaaaatc aaaggtccta aggttgaatt tttctctcct aaagaaggag accctgctga
     2041 ttacgtcaag gtagtgatgg aagacggaga agaagtgact attacaaata catgtgcagc
     2101 caatgttctt ggattagtgc aagaagaaca tttttcttat ggaaatgtcc catctgcacg
     2161 aaaagccata caggcattag cagactattg tcatacgacg gttgaagaca tcgcagagca
     2221 gatcatggaa aaatcctatg ctaagattga accggtgatt ttagaattgg cagacaagta
     2281 tcacttggag aaagatcaga tttctcttgt aggtgtaggg ggcggcgctg cctcattgat
     2341 tacttacttt agtaataaaa tgggtgtgaa atattcgatt cctgaaaacg ccgaagtgat
     2401 ttcttctatt ggtgtagcac ttgcaatggt ccgagatgtt gtagaacgta tcatcccttc
     2461 gccaagtaaa gaagatatac gatcgttgaa aaatgaagcg atgaataaag cgattgaatc
     2521 aggcgctaca ccagaatcga tcgaagtcca cgtagaaatc gatccacata cttcaaaagt
     2581 aacggctatc gctactggtt ctacggaagt gaaagcaacc gatctaacca aggagatcac
     2641 aacagaagaa gcactagagc ttgctgcaga ggatatgcga ttaaataaaa atgaagtttg
     2701 cttattggaa aatacacctt tcttttatgt atgcggcgaa cagaatcgtt caaaaaatgc
     2761 tggaagtctt cggatcatcg atcaaaaagg atttatcaag gtccaacgtg gacatgcttc
     2821 atgtatgaaa acaactgcag ccaattatat gacagctgtc gaacaacttt gggaagatat
     2881 ggcagtttat caaactgaat tgattgcccg accagaattt tatctctgct taggagcaag
     2941 agtctctgat tttacagcga cggatctgga acaactacag cttttgatgg atctggaagt
     3001 atctactatg gaaccggagg aagaagtgat cgtcgttgcc ggaaatatca aacaaacata
     3061 agttagaaga gttactaaac gaattacaac agatccccga agaaatttgg ggattctacc
     3121 agtttcggcg agatttattt tggaaaaaga ttcctttgtc caagcagaaa attcttatac
     3181 aacaatcaat cgattgtggt atcgaaacgg catgtagcat caaaaaaaag tacccttttg
     3241 ccgatgtagg agaaatctgt gaacaaatgg ctgttccaat cgtttcctgt gaatcagagc
     3301 aaataaacga acgaatcact tttgcaactt atgcagaaga tgaagggatc cgattgatga
     3361 cggagccgtt agaaaaatta aaatgttcag gactagcttc gatctctaaa gaaacagcgc
     3421 aagctttgat tattggacat gaactatttc accacatcga agcttctgtt aagggaattt
     3481 atacgcaaag cgaaaaaatt gtgctgtggc ggttgccttt ttatacacat caatcaaaca
     3541 ttcgtgcatt gagcgagata gcagcgatga gtttttcaaa agagatgaat caaagcgatt
     3601 tttcgcctta tgtattagag gcagtcttac tttggccata taatgaaatt cgtagccaag
     3661 ggatcttaga agaaataaaa gaaatagaaa aaagatgtac ggagtatgat ttagattaca
     3721 aataaagaga ctgtgacaaa agtcgtgtca cagtcctttt tttccgaata aacggtgttc
     3781 tcctgtcaac tcctcggtca caagtcaaaa tattcaacaa acatgagaag ctgttttttg
     3841 aaattgttcc ttgtgactcg gagatgaacg gcaggctcac gacctcttgg aaaaaggtgt
     3901 tcaaaagctt gcatctgcgg taataagaac agccaagtta aaaacataag aagctatttt
     3961 tacttggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct caataaacgg
     4021 tgtgcaatca gctgaccctc ggtattagct caaaaaaaac ggcaaaatat gaggaactat
     4081 tttgccgttt atttctctaa tactcaggtc aaaacgctga ttccaaaacc tcttatttga
     4141 tgggtctgtc ctgaatatct tcaaaataat cggggtaatt atgaatcacg tattcttgct
     4201 cctcgataat catatgtaaa tgcatcgtgc aaagaaatcc gacttcatca aagttatgat
     4261 caatcattga ttgaagcatt gtctgatgtt catctaatac tcgaccccag tctaattctg
     4321 aaatcgtcaa acgtaaccat ctgaaacggt tcaagtgcgt actataactt tctagccaat
     4381 cccaaatttc tcgttttcca gcaatttcat aacaagttcg gtgaaaatca gtatccaaat
     4441 caaaaaagct tttttatttt gagcgatcac tgcctgatcg gtttgttcta gtattttttc
     4501 tagtttagct tgatcttgct tggtcatttt cgcactgcat tcttgcagga tcggtttttc
     4561 caacttttcc cgcgtataac gggctaatga agcagatcgg atatcgattt ttgaaacata
     4621 agtgccggac tgtggaatgg tttttacaag ctcttgattg cgcagttgga tcagtgcttc
     4681 tcgaatcggt gtacgcccga tagctagttg ttcttctaac actttatcgg agattttact
     4741 tccgggtgct aactcggaat aaatgatttg tttacgtata gattcataag cttgctgttg
     4801 caaattattg ataaccattt aaccttcctt tctatgcaga tataatctat tataacataa
     4861 atcgcttaca aatcgtgtgg gcataaaaac acagtctgca aaaaaagccc tgataggcat
     4921 gcctattaga gcctcgaaaa gaaaaatatt gaatcaatct ggtcgtacct cttggatcgg
     4981 tttgacacga ccgccgattc ttttagcaaa agcttcggat tcttttttgt ctttgaaaat
     5041 gagcagattg tctaagtttt tttcccgagt gcgacagcca gttttatcga tgtaaccgtg
     5101 cattacttta acgacataca tggggatcac ctgctttttt cttttcatta tacgaactac
     5161 tcgacacaat acaagaaaaa tgcttagacg gtctttatta agaatttaca tcatccaaag
     5221 aagcgtacgc ttggaataac tgttctaact ccggattgac tttgctcagc ttcactaatc
     5281 gttgcgaatc agaaagtaaa aaacagtgtt tactactgcc agtagttttt aattttttgt
     5341 cttcagttcc cacaatttcg tagctaaaat ccaaccgtgt tcccgtatac ttttggatag
     5401 ttgggtggat gctcactttt tctccgtaat ggatcatttc tttatagctg caatttactt
     5461 ccagaacggg gatgatgatc ccagattctt cgattttttt atagggaaac cctagatgta
     5521 ccaataaggc tacccgagcc tcttcaaacc agcggatata attgctgtga tgaataatcc
     5581 ccatttgatc tgtttcataa taaaaaggtt ctcgcacata acctgtaaat ttctccatga
     5641 ctcatgcctc gttttccatt gattttttac aaaaataatt catccacttc ggaagtgctt
     5701 cgctgatttg tgtcggcaaa acaatatatt gttcttttgc cagctggtct ccaatgaaac
     5761 tatgaagata aacagctgct gcaatcgttt ggtcattttg aggaaactgg gctaaaaatc
     5821 ctgtgatcat cccagctaaa gtgtcaccca tgccgcctgt tgccatagca gcagaaccta
     5881 aaggattggt gtagaagtgc tggtgaccat aaatttttgt ctcatgactt ttcaaaacga
     5941 gcacagcacc gatttcctgt tgcttctttt tgttttcttt atcccgttgt tcttgtatcg
     6001 gtagagaact caaccgttgc cactccattt gatgaggtgt aagtacagtt tgttcgggat
     6061 agggtagcaa aagatgatta gcaacaagta aacttaaagc agagccatca atcaccagcc
     6121 attgttcttt tgattggttt tctagtactt gtttgaaacg ttccaaactc ttagaagaag
     6181 tacccaatcc gggaccaatc aagagtacat ctgcttgctt tattacggaa agaaactggt
     6241 cagtatccgt ccaatctaca atcattgctt ctggcagatg actgtgaaga gcactccgat
     6301 ttttttcatc agttactaca gtcgtgagac ccgctccact gtgtacggca gctaaagcac
     6361 tcataatgat tgctccgcca tattgttcat tgccgccaat caaaacgata cgtccaaatg
     6421 ttcctttatg tgaaatcttt ggacgaggtg tgatgactct tttcactagt tgttcgttta
     6481 tcagcatcga aaaacctcct tttactcatt atagcgtata ttttttttag agaaaaacag
     6541 ataagaaaag gaattgtcag attttttgaa ctattttttt ctgtaatttg tggtatcatg
     6601 aacacgaaga cttaaataag tggaggatta actttatgac aattgattgg caaaaagaag
     6661 tagaagcacg taaagaagac ttgcttgaag acttgaaaaa tcttttacgt gtcaacagcg
     6721 agcgcgatga ttcaaaagta acaccagatg caccatttgg acctggacct cgcgacgcat
     6781 tgaaacatat gttagcttat ggcgaacgtg atggatttaa agtaaaaaat gtcgataact
     6841 atgcagggca tattgatctt ggcgaaggag acgaaacgct agggatattt ggacacatgg
     6901 atgtcgttcc tgcaggagat ggctgggaca cagatcctta tgaaccagta atcaaggatg
     6961 gaaagatctt tgcacgcgga tcaagcgatg acaaaggtcc aagtatggca gcttactatg
     7021 cgatgaagat cattaaagaa cttgacttga aactatcaaa aaaagttcgc ttcgtagtcg
     7081 gcagcgatga agaaagcggc tggggcgata tggcttatta tttcgaacat gaagaagaac
     7141 cagattttgg tttctcacca gatgctgaat tcccaatcat caatggtgaa aaaggaaatg
     7201 tttctttagc tttacgcttc aaaggcgaca atgcaggaga ttatgtcttg aaatcttttg
     7261 tttccggact tcgcgaaaat atggtgccag gaacagcaac tgcagcactt caagtaccaa
     7321 gtgcagatgc agctatcgcg atggaagaag cattttacca attcatcgaa gcaaatccag
     7381 taagcggaac gattgaagcg gacaatacgt atgtaaaaat cgaattagtt ggtaaaggcg
     7441 cacatggtgc aagcccacaa tctggtatca atgcaggttc tttcttggca ttgttcttag
     7501 ataactatga attcctagga tctgctaaac aatttatcca tgtagcagct gcttatgtcc
     7561 atgaagattt ttatggagaa aaactaggag tcgcttatga agatgaaaaa atgggcaaat
     7621 tgacaatgaa tgctggacta tttgcttttg aagaaaatgg tacagaggaa gcgaacttca
     7681 tcaatatgaa tttccgtttt ccaaaaggtg taacagtaga cggattgcaa agtgacatcg
     7741 aacaaacagt ggggcaagaa ggcgcaacag ttactcgagg tgctcgcgta atggaaccac
     7801 attacgtacc aatggatgat ccattggtgg ctacattatt gcaagtctat gaagaccaca
     7861 ctggagaaaa aggctacgaa caaatcatcg gtggcggaac ttacggacgt ttgttgaaac
     7921 gtggcgttgc ttatggagcg atgttcccag gatatactga tacaatgcat caagcaaacg
     7981 aatttatgag tcttgatgac ttgttcagag caacagcaat ctatgcagat gccatctatc
     8041 gtttggcgaa ataaaaatac taaaaaa
//
LOCUS       DAYNVV010000095         7755 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.098, whole genome shotgun sequence.
ACCESSION   DAYNVV010000095 DAYNVV010000000
VERSION     DAYNVV010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.098"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..280)
                     /locus_tag="ACGXWR_002650"
     CDS             complement(<1..280)
                     /locus_tag="ACGXWR_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HFK0804132.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAI"
     gene            426..509
                     /locus_tag="ACGXWR_002651"
     CDS             426..509
                     /locus_tag="ACGXWR_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HFK0804133.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            634..1371
                     /gene="erm(B)"
                     /locus_tag="ACGXWR_002652"
     CDS             634..1371
                     /gene="erm(B)"
                     /locus_tag="ACGXWR_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFK0804134.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1541..1801
                     /locus_tag="ACGXWR_002653"
                     /pseudo
     CDS             1541..1801
                     /locus_tag="ACGXWR_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            1964..2629
                     /locus_tag="ACGXWR_002654"
                     /pseudo
     CDS             1964..2629
                     /locus_tag="ACGXWR_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2665..2910
                     /locus_tag="ACGXWR_002655"
     CDS             2665..2910
                     /locus_tag="ACGXWR_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFK0804135.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            3013..3882
                     /locus_tag="ACGXWR_002656"
     CDS             3013..3882
                     /locus_tag="ACGXWR_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFK0804136.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3863..4597
                     /locus_tag="ACGXWR_002657"
     CDS             3863..4597
                     /locus_tag="ACGXWR_002657"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFK0804137.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4630..5538
                     /locus_tag="ACGXWR_002658"
     CDS             4630..5538
                     /locus_tag="ACGXWR_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFK0804138.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            5535..6077
                     /gene="sat4"
                     /locus_tag="ACGXWR_002659"
     CDS             5535..6077
                     /gene="sat4"
                     /locus_tag="ACGXWR_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HFK0804139.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            6170..6964
                     /locus_tag="ACGXWR_002660"
                     /note="aph(3')-IIIa"
     CDS             6170..6964
                     /locus_tag="ACGXWR_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HFK0804140.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            7240..>7755
                     /locus_tag="ACGXWR_002661"
     CDS             7240..>7755
                     /locus_tag="ACGXWR_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFK0804141.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIE"
BASE COUNT         2698 a         1187 c         1603 g         2267 t
ORIGIN      
        1 cgatggctcg atacaaataa tgccattttc ctttaatttt gatgtacgtt tcatccattt
       61 tccatgaata aaaggatttt ttatttttct ttttccaaat ttgatagagt agtttgccat
      121 attcttgcac ccaacgataa atcgtcgtat gagaaacgtt aatgccacga tcatataaga
      181 tttcttgaac ttcacgatag ctaaggttat aacgaagata gtagcccacg gctacaataa
      241 tcacatcctg ctgaaattgc tttcctttaa aatgattcat cgtcattcct cctgctatct
      301 ttttctatta ttctacctta tttgatagta gatttaaaac tttgcaacag aaccattttg
      361 tgtataatag gaattgaagt taaattagat gctaaaaatt tgtaattaag aaggagggat
      421 tcgtcatgtt ggtattccaa atgcgtaatg tagataaaac atctactgtt ttgaaacaga
      481 ctaaaaacag tgattacgca gataaataaa tacgttagat taattcctac cagtgactaa
      541 tcttatgact ttttaaacag ataactaaaa ttacaaacaa atcgtttaac ttctgtattt
      601 atttacagat gtaataactt caggagtgat tacatgaaca aaaatataaa atattctcaa
      661 aactttttaa cgagtgaaaa agtactcaac caaataataa aacaattgaa tttaaaagaa
      721 accgataccg tttacgaaat tggaacaggt aaagggcatt taacgacgaa actggctaaa
      781 ataagtaaac aggtaacgtc tattgaatta gacagtcatc tattcaactt atcgtcagaa
      841 aaattaaaac tgaacattcg tgtcacttta attcaccaag atattctaca gtttcaattc
      901 cctaacaaac agaggtataa aattgttggg agtattcctt accatttaag cacacaaatt
      961 attaaaaaag tggtttttga aagccatgcg tctgacatct atctgattgt tgaagaagga
     1021 ttctacaagc gtaccttgga tattcaccga acactagggt tgctcttgca cactcaagtc
     1081 tcgattcagc aattgcttaa gctgccagcg gaatgctttc atcctaaacc aaaagtaaac
     1141 agtgtcttaa taaaacttac ccgccatacc acagatgttc cagataaata ttggaagcta
     1201 tatacgtact ttgtttcaaa atgggtcaat cgagaatatc gtcaactgtt tactaaaaat
     1261 cagtttcatc aagcaatgaa acacgccaaa gtaaacaatt taagtaccgt tacttatgag
     1321 caagtattgt ctatttttaa tagttatcta ttatttaacg ggaggaaata attctatgag
     1381 tcgctttttt aaatttggaa agttacacgt tactaaaggg aatggagata aattattaga
     1441 tatactactg acagcttcca agaagctaaa gaggtcccta gcgcctacgg ggaatttgta
     1501 tcgataaggg gtacaaattc ccactaagcg ctcgggaccc cttgtaggaa aatgtcctaa
     1561 gtgtggcaac aatattgtat taaaaaaatc gttttatggt tgttcaaatt atcctgaatg
     1621 taagtttact ttagctgaac attttagaaa gaaaaaacta accaaaacga atgtaaaaga
     1681 attactggag ggaaaagaaa ccctggtaaa aggaatcaaa aacaaagaga aaaagcccta
     1741 caatgccgtt gtaaaaattg gggaaaaggg atatattgat tttatctctt tttcaaaata
     1801 aacatggggc tgacccaaaa gtagctccta tatgaaaaat agaggtcttt ccatttagat
     1861 agtagtggaa agacctctat ttatcttttg aaagtgaata caaaaataaa gcacactctg
     1921 ctataatata ggtgattaat ccatttgaga gaggtgcttt atcatgtatc aaaattatac
     1981 cataaaccaa ctttgtttgc ctatagatct tgaaattaaa ttagaagaaa atgattttgc
     2041 tcatgccatt gtgcagtttg ttgactctat tcccgatgaa gtctttcttc cttattatca
     2101 atctatgggt agaccccaat atcatcctcg tatgctactt tccattattc tttgtgccta
     2161 tattcaaggg gtttattcgg gccgccaaat acaaaatatg ctgatagata gtattcggat
     2221 gcgctactta tctcaagagc aattccctaa ctttcgtact attaatcgtt ttcgcgttca
     2281 tccgattatg aacgatattc tagatcattc atttgttcaa tttcgtgagc tactggttca
     2341 aagtggctta atcagtggca gtgctctata cattgatggt acaaaaattg aagcggatgc
     2401 gaataaatac tctttcgttt ggaaaaaaag tattttaaag tataaggata gccttgatca
     2461 aaaagccctt gaaaactacc aacaaatggt ggaaacaaaa atcttacctg agttaataga
     2521 tgatttaaag gatgaacttt ctatagaaga gattgaaagg attcgtcaat ctttggaaga
     2581 aaaggaaaat caattaattg aagcgattga ccaaaccgaa acagtagaag ggggctgacc
     2641 cattattaat aaggagtgga caacatgatt gatgtaaatg agctattgga agaagctatt
     2701 agagaaactg aaaatctaaa tgatggcgaa gtttttcttg ttaaagattt attcaaggga
     2761 tatgtgggga ataggatacc cagaaaggat cgacttctgc ttggaacgtt atttttaaac
     2821 catgttagca aaatgaatgg taatttaaag gctattgaaa agacttcatc taatcagcag
     2881 aggtataaaa agacaattga taagttttaa ctatcttttg tgaaattaaa aaaattataa
     2941 atatgttgag tagaagcaaa agatttggct tggaattttt acagcagtga atcgataaaa
     3001 ggagcatgct tgatggtaga taatattatt aaatcagtag cagagaaatt atcctctctg
     3061 tcttatatag aaggtattgt tttaggtggt tcacgtgcaa ggggcaccca tacagaggat
     3121 tcggatatag atatcggcat ctattacaat tcagaatcat ttgacataaa tactattaat
     3181 caattcgcta caaagctgga tgatgagcat agaaataacc ttgttgtacc tcccggagca
     3241 tggggtgatt ggattaatgg cggcggatgg ttagtcataa acgggtatca tgtggattta
     3301 attttacgtg atattaaacg tgtggaacaa ataatgaaag atacagagca cggaattgtt
     3361 actgccaatt atcagactgg gcatccccat ggttatatta gtgcaatgta tcgaggagaa
     3421 ttagcgatta gcaaaatact atatgctaag aatgaaagct tatgcgaatt aaaaaaacag
     3481 gcagaaactt atcccaatgc tttgcagaaa agtttagtta acttttttat gtttgaagca
     3541 gggttctctt taatgtttgt aaaagcaaat tcgggaacag acgataaata ttatattgcg
     3601 ggtcatgttt ttcgtatagt ttcatgttta aatcaagtgt tatttgcatg taataatgct
     3661 tattgtatca acgaaaagaa agctataaaa ctgcttgaaa cttttgaaca taaacctgaa
     3721 aaatataccg agaaggtaaa tcatattttt gaagtactcg gtatctcact ttttgaatgc
     3781 tacgacatga ccgagaagct ttataatgaa gtgaatgaaa ttgtatcgga gataaataac
     3841 tttttaaacg aggagagttc agatgaaaga aaacaaatat gatgataata tattttttca
     3901 aaaatacagt caaatgagtc gctcgcagaa aggactggct ggtgcgggag aatgggagac
     3961 tttgaaaaag atgctacctg attttaaggg taagcgtgtg cttgatttag gatgcggcta
     4021 tggatggcac tgtatatatg cgatggaaaa cggtgcttcc tctgtagtag gtgttgatat
     4081 ttctcataaa atgctcgaag tagcaaaagg aaaaacccat tttccacaga ttgaatatga
     4141 atgctgtgcc atagaagatg tggatttccc agaggagagc tttgatgtaa tactaagttc
     4201 gcttgcgttt cattatgtag cagactatga gaatttaata aaaaagatat ataggatgct
     4261 gaaggctggt ggcaatttag tttttacagt tgaacatcct gtttttactg ctcatggaac
     4321 acaagactgg tattataacg aaaaaggaga aatactgcat ttcccggtgg acaattatta
     4381 ttatgagggc aaacggacag ctatgttttt ggaagaaaag gttacaaaat atcatagaac
     4441 actgaccaca tatctaaata cactgctttc aaatagtttt ataataaatc agattgtgga
     4501 gccacagccg ccagagaaca tgatggatat tccggggatg gcggatgaaa tgcgacgccc
     4561 aatgatgctg attgtatcgg caaaaaagaa gatgtaataa tatagaaaaa ataaacgagg
     4621 agtatgtaaa tgagatcaga aaaagaaatg atggatttag tactttcttt agcagaacag
     4681 gatgaacgta ttcgaattgt gacccttgag gggtcacgcg caaatattaa tatacctaaa
     4741 gatgaatttc aggattatga tattacatat tttgtaagtg atatagaacc gtttatatct
     4801 aatgatgact ggcttaatca atttgggaat ataataatga tgcaaaagcc ggaggatatg
     4861 gaattattcc cacctgaaga aaagggattt tcctatctta tgctatttga tgattacaat
     4921 aaaattgatc ttaccttatt gcccttggaa gagttagata attacctaaa gggcgataaa
     4981 ttaataaagg ttctaattga taaagattgt agaattaaaa gggacatagt tccgactgat
     5041 atagattatc atgtaagaaa gccaagcgca agggagtatg atgattgctg caatgaattt
     5101 tggaatgtaa caccttatgt tattaaagga ttgtgccgta aggaaatttt atttgctatt
     5161 gatcatttta atcagattgt tcgccatgag ctgctgagaa tgatatcatg gaaggtcggc
     5221 atcgaaacag gctttaaatt aagtgtaggc aagaactata agtttattga aaggtatata
     5281 tccgaggatt tgtgggagaa acttttgtcc acctaccgga tggattccta tgaaaacata
     5341 tgggaagcat tatttctatg ccatcaattg ttcagggcgg tatccggtga ggtggcggaa
     5401 aggcttcatt atgcctatcc ggagtatgat aggaatataa caaaatatac cagggacatg
     5461 tataaaaaat acactggtaa aaccggctgc ctggatagca catatgccgc tgatatagaa
     5521 gagaggcggg aacagtgatt acagaaatga aagcagggca cctgaaagat atcgataaac
     5581 ccagcgaacc atttgaggtg ataggtaaga ttataccgag gtatgaaaac gagaattgga
     5641 cctttacaga attactctat gaagcgccat atttaaaaag ctaccaagac gaagaggatg
     5701 aagaggatga ggaggcagat tgccttgaat atattgacaa tactgataag ataatatatc
     5761 tttactacca agacgataaa tgcgtcggaa aagttaaact gcgaaaaaat tggaaccggt
     5821 acgcttatat agaagatatc gccgtatgta aggatttcag ggggcaaggc ataggcagcg
     5881 cgcttatcaa tatatctata gaatgggcaa agcataaaaa cttgcatgga ctaatgcttg
     5941 aaacccagga caataacctt atagcttgta aattctatca taattgtggt ttcaaaatcg
     6001 gctccgtcga tactatgtta tacgccaact ttgaaaacaa ctttgaaaaa gctgttttct
     6061 ggtatttaag gttttagaat gcaaggaaca gtgaattgga gttcgtcttg ttataattag
     6121 cttcttgggg tatctttaaa tactgtagaa aagaggaagg aaataataaa tggctaaaat
     6181 gagaatatca ccggaattga aaaaactgat cgaaaaatac cgctgcgtaa aagatacgga
     6241 aggaatgtct cctgctaagg tatataagct ggtgggagaa aatgaaaacc tatatttaaa
     6301 aatgacggac agccggtata aagggaccac ctatgatgtg gaacgggaaa aggacatgat
     6361 gctatggctg gaaggaaagc tgcctgttcc aaaggtcctg cactttgaac ggcatgatgg
     6421 ctggagcaat ctgctcatga gtgaggccga tggcgtcctt tgctcggaag agtatgaaga
     6481 tgaacaaagc cctgaaaaga ttatcgagct gtatgcggag tgcatcaggc tctttcactc
     6541 catcgacata tcggattgtc cctatacgaa tagcttagac agccgattag ccgaattgga
     6601 ttacttactg aataacgatc tggccgatgt ggattgcgaa aactgggaag aagacactcc
     6661 atttaaagat ccgcgcgagc tgtatgattt tttaaagacg gaaaagcccg aagaggaact
     6721 tgtcttttcc cacggcgacc tgggagacag caacatcttt gtgaaagatg gcaaagtaag
     6781 tggctttatt gatcttggga gaagcggcag ggcggacaag tggtatgaca ttgccttctg
     6841 cgtccggtcg atcagggagg atatcgggga agaacagtat gtcgagctat tttttgactt
     6901 actggggatc aagcctgatt gggagaaaat aaaatattat attttactgg atgaattgtt
     6961 ttagtaccta gatttagatg tctaaaaagc tttaactaca agctttttag acatctaatc
     7021 ttttctgaag tacatccgca actgtccata ctctgatgtt ttatatcttt tctaaaagtt
     7081 cgctagatag agttctatat tagagatgta aagagttttg gtgaagaggt ttgtgagtat
     7141 ggcttttata accagggtgc aatgagaagc actaacagca gctagcttaa gaacgcatag
     7201 gatatacttt ttatggaagt cacagaggag gaataaaatt tgaacaggat taacagagta
     7261 acctctattc ttattcagct gcaatcaaaa aaaataattc ctgccaaaga aattgcacag
     7321 cgatttaata taagcttaag gacagtttac agagatatcc ggacacttga agaagccgga
     7381 ataccaattg gatctgaggc cggaaaagga tattttcttg tagagggctt cctacttccg
     7441 ccggtaatgt ttacagcggc ggaagtgggt gcattgatta cagcagggaa atttttaaat
     7501 tgccatggag atgaatcatt tataaaggat tttgattcag ctatgtataa aatcaaatct
     7561 attttgaagc atggtgaaaa aaactatgca caggagttgg agaacagtat taacgtgtac
     7621 agcacatctg gacagaaaaa tacattggcg gataacgtta ttgcagcaat tcagactgca
     7681 atctgcaata aaagggtaat atcaattcaa tatcctgcat caggagggca agaaccggaa
     7741 agcagaatga tagag
//
LOCUS       DAYNVV010000096         7598 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.099, whole genome shotgun sequence.
ACCESSION   DAYNVV010000096 DAYNVV010000000
VERSION     DAYNVV010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7598
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.099"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(136..426)
                     /locus_tag="ACGXWR_002662"
     CDS             complement(136..426)
                     /locus_tag="ACGXWR_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804142.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(544..804)
                     /locus_tag="ACGXWR_002663"
     CDS             complement(544..804)
                     /locus_tag="ACGXWR_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804143.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(941..1354)
                     /locus_tag="ACGXWR_002664"
     CDS             complement(941..1354)
                     /locus_tag="ACGXWR_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HFK0804144.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1810..2295)
                     /locus_tag="ACGXWR_002665"
     CDS             complement(1810..2295)
                     /locus_tag="ACGXWR_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804145.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2434..2649)
                     /locus_tag="ACGXWR_002666"
     CDS             complement(2434..2649)
                     /locus_tag="ACGXWR_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HFK0804146.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2873..3673
                     /locus_tag="ACGXWR_002667"
     CDS             2873..3673
                     /locus_tag="ACGXWR_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFK0804147.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3692..5560
                     /locus_tag="ACGXWR_002668"
     CDS             3692..5560
                     /locus_tag="ACGXWR_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFK0804148.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5553..6044
                     /locus_tag="ACGXWR_002669"
     CDS             5553..6044
                     /locus_tag="ACGXWR_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HFK0804149.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6032..6586
                     /locus_tag="ACGXWR_002670"
     CDS             6032..6586
                     /locus_tag="ACGXWR_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HFK0804150.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6604..>7598
                     /locus_tag="ACGXWR_002671"
     CDS             6604..>7598
                     /locus_tag="ACGXWR_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HFK0804151.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2235 t
ORIGIN      
        1 tgttactatg aataacataa taagaaagta aagtggattg atttgagatc tttttatact
       61 tcaaaaaaga taacacccaa ctttcaaaaa tatgttttgg aagttgggac aaacgagtta
      121 atacatttta atacattatt ttttattcaa aaaaaatagc acaatggcaa agatcgtaag
      181 agagatcata agccccaatg aatgactaaa aagaaaagca gaatcacatg ccatatcatc
      241 ccatatttct tcaagaaaat aaataagcgg gaaaaaggga aggaatagta gaacatcgat
      301 ccagcaccat ttttttcttc ttttgaaata acataaaaca ataaacatga acgtgcaggg
      361 aagtaaaaac aaagctttac tcataactaa caaaatacca gctcctttta tttttttctc
      421 ccccacattc aaagagtaac aatggtatgt acttaataat agaaaaatgg atcaacttgt
      481 atgaataaca gctgaaaaga tctgcaccaa ataaaaaact tccagccaaa actgactgga
      541 agtttatttt tttctgaaat attctaacac aaatatgaaa aagatggccg aagctaataa
      601 gccgatttcg tagcaaaaca atgagatacc agagtcgtaa taataaaatc ctctaatctt
      661 atggataaaa tagatcatcg gacaagcaga taagagtaag tatttgttag gccttttgaa
      721 taagtaaaag aaagcactgg tcattatgat aaatggtatc caaaacaaaa gtttacttaa
      781 gacaatcaaa tgatcaactc ccatattttt taccaagaga gatcataaca tctttatcgt
      841 aaaaacaaaa tatttttttg ctcattttga aaatttaaac atactcgttc ttatccaaat
      901 atataaaaat cgcccctcat tcatcgagag gcgataagtt ctaatttaac tcaatttttt
      961 ttgtttcttt tggctgataa gctgttttag gtaataccaa tttcagcaca ccgtttttaa
     1021 aggttccagt gattttttct tcatcaacat taggaagata gaatgaacgt ttgtaagaga
     1081 ccgaatgtct ttctttccgt acatagttgc catcttcttt atcttctgta tgggactcat
     1141 gattggcgga gatcgtcaaa gtattatctg aatattcaac tgtcgtgtct tctttgtcac
     1201 agccaggcat atcagcagtt agtttgtatt ctttttcatt ttcgactaaa tctacttttg
     1261 gataacttga aacacctaaa aaatcattga atgctggact aaacacgtca ttgaaatcag
     1321 ggaacatgtc gcgaatgcta ggtacatttg ccatttttga tcatcctttc aataagtatt
     1381 ttttatttat ccctatttac gtaataactc tattttgaaa aaaatgcaag tataatggtt
     1441 agctttgtga atatttcatc taatacgata caaaggctat ctttctaatt tgaaaaaggg
     1501 atcattaaaa taataagaag aaaatatgtc aaaaggtaaa aaagtaaatt cttctatcca
     1561 aatatagaaa aattgaatct agaaaaccgc ccgacaataa atttcattaa ctcagttgac
     1621 cgaaaatgaa gtagatacca aaaatttatc aagagagcaa gtagagaagt gagtatattc
     1681 ataagagaaa tagctgtaac gaattattag gttaatgcaa atgcttattt atactccgta
     1741 taactttctc agaaaaaatg ataccaataa tgacttgcta gtactgtaaa tccgtataat
     1801 atcatctaat caaaatggtg ttccatttgc atctgtcatc gtaatcgatc cttcgggtga
     1861 cactcgataa aaaccaacgc ttccagatcc tccttgggaa cggatttgtt tgctggaagc
     1921 tgtgaacaaa taatctcgat caattttttg ataaaagcta ataacaatat cgtcactttg
     1981 taattcggaa cggtgggcaa taagaaatag aagtgctttg tcagagtttt ctaatggaag
     2041 agaaggtaca gtgctttctt gcatttcaga tgttgaagaa atgctaaacg actgaatact
     2101 tgattggcta tgttgcgaat ctacattacc agtagaagta ttagtaatgg aagtagtaga
     2161 agtactttta gttgaaccaa cctcagttgt tgaaatggct gctgaagatt ctttaacaga
     2221 attctttgtt ttatatccac aggcagaaaa aagtattaca gttcccaaca agcctgcgta
     2281 aatcccttta tgcatgatag ctcctcctaa aatagattat ctttattcag tatatcactt
     2341 aaacaaagaa aagcagatgg tttaaaatga aaaaaccttc ccaataaagg gaaggttcat
     2401 gaagataata acttttttaa taattatagc tttctaatat ctttcatcaa cttttctagt
     2461 aatcattggg aaaaatttca agcagtagat cgcacaaata cctacgacga tataaatgat
     2521 cttcgcaaaa atagttgttg aaccaccagc aatcatagct actaaatcaa gttcgaacaa
     2581 gcctaccaac agccagttca accctcccac aatcaataaa gttaatgcaa tagcatctaa
     2641 agttttcatt agaattctcc tttcttaaat gataaaacaa ttatatatca aaaagagaaa
     2701 cattgcttat ataacgctca ggaattttag caatctatgc aaaaagatga aaattttttt
     2761 tgctcttcca ttagtacaca ttttttagct gaagctgtaa atttcatgtc ttaatttttt
     2821 ttagtgagct tttatactgg atttgtaaga aaaaagaagg agaggatcac atatgtcgga
     2881 ttggttggat attgcaggaa aagtagtaat tgtaactgga ggttcctcag gaattggaag
     2941 aagtatcgtc gaaaatttgt tgaagcagaa tgcacaagta gcgaattttg atgtaactga
     3001 atgccgtata cagcatgaaa acctactatc tttaaaagtc gatgtgtctt ctaaaacgga
     3061 catagaagaa gggatatata aagtaatgaa acatttcaag acgatcgatg gtctagtcaa
     3121 taatgcagga ataaatattc cttctcttct aatagataga aatcatccaa aaagcaagta
     3181 tgaattatca gaacaagttt ttgataagat gatcgctgtc aatcaaaaaa gtgtatattt
     3241 gatgagccaa gcagttggaa gaatcttggt gcaaaaggga tcaggagtga tcgtgaatct
     3301 ttcttctgaa tcaggattgg aaggatcaga aggacagagc tgttatgctg ctacaaaagc
     3361 agcgatgaac agttttactc gttcttgggc aaaagagtta ggaaagagga atgttcgtgt
     3421 ggtaggtgtt gcaccaggga tactggaaga aaccggtttg agaacacaag aatatgaaga
     3481 agctctttct tatacgagag gtataagcgt cgaacagctg agaaacggtt acagtcgaac
     3541 aagtacgatc cctctaggaa ggagtggtaa gctgcaagaa gtggcggatc tagtctgcta
     3601 ttatctttca gaaagatcaa gttatatcac tggagtcacg actaatattt caggaggtaa
     3661 aacaagagga taaaggatag gggggacgca cgtgacgcta gtaaacagat ggtaccaatt
     3721 attgaaatta ctagtcactc acaagaaagt ttcaatccag gaagtgcaaa aagaaatcaa
     3781 aaccagtaat caaaccataa aaaaagatat tggggagttg aatgaagaaa ttgccggtat
     3841 tgcaaaaatc atccaaaaaa acaaacattt tgaacttgaa atttatgatt ttgatttttt
     3901 tgatgagatc atgcaaggaa aattgaaaac agccagtgat ttcaattcgg catccaaaag
     3961 aatcgcttat ttactaaata ggctgatcga aacagaggat ttcttacgta tggatgattt
     4021 gtctgaagaa gtcggtgtca gcagaggaac agtggtcaag gatctaaaga cattaaaaga
     4081 gatgatcaat gattttgatg taaagattac aggcacacca aataaaggac taagaataat
     4141 aggagatgag ctagaattac gactactttt attttatttt gtttctccct acttttcaga
     4201 gacgaaaaca gaacagtttc tagaagaaaa acaagcaatc aaacattttc agaagaagac
     4261 gaatgctagt aaacaagaaa tcaccctttt aacgaaagtt atcggtattt ctttgaatag
     4321 aatctctagt aactatctgt tgaagaagcc catcaatcgt tacagtgggt gttttgaata
     4381 tatccaagaa ttcaatgaac tgatcaatca gttggaagaa atctatgaac taactttgag
     4441 ccaatatgaa aaagatttta tcagttttcc tttgaacatc atcaacacaa gtataacgat
     4501 gataaggaaa gctaactctg atttgcgctt atatttcgac cccatgatga tgcgtattcg
     4561 acgattagat ctcattgatc tggatgagtc cttcttatat caagagatga aacagcacct
     4621 ctctttattg ataaatcggg taatttttcg ttatcgattg actgatttat tttatggtga
     4681 gatagaaaaa aagtatcctt tttcttacca aatcgctagc gaatgcatac aagcattaga
     4741 agctatcttg caacataaga tctctaaagt agagatcagc tacctaacgt tgtatttgga
     4801 gttagcattt cgatatcaaa aagagcattt ttcctctaaa aaagtagcca ttgttcatac
     4861 gacaggaaaa ggaacagcat taatgatcca aagacaaatc aaaaggatat tggggaggga
     4921 tatacaaata acacatgttt cagaagaaca atatgaaaaa gtagatctaa acaaatattt
     4981 cgctgttttt acaacgattc cgttaaaaaa tgtaaatgaa gagacaccgg tgatccattt
     5041 gactaatctt tttgatgact cttggttaag ggcacaatgg caaaaagcaa aaaaaaagcg
     5101 attagccggg tttcattcta ctgttttttt ctatcaaata tggaaagaaa aaaagacgta
     5161 tcaagaatat ttaaacaaat tagtcgctcc tttgatcaga ggctattatg tggatgaaga
     5221 atttgaaaaa aggatcttga aaagagaata tcagcaaagc acatttgtta acaaagaatt
     5281 tgcttttcct cacacaacca accagctatc tcaacacatt gttttatcag tagggctaat
     5341 aactgatcaa ggtttagcag aaacaggagg aaatggagtt atttttttat ttgccatacc
     5401 tgaagaaatg acggctgaag ttgagaatga attatttgag ctatacgata tcctatttga
     5461 actcataaaa atgggaatag atgagtttat tgaattagca ccgacacaag aatcattttt
     5521 aaaactaatc aaaagtaaag gagagagact tcatgaatga tatgtatcta ttcatagttt
     5581 tcgcagcttc agcttatgtg ctgcaagcag ttatcagttg gaagcaacta aagcatttca
     5641 atcaaacata tagcgaactg cgaagaaaag gaaaagtagc gattggtaaa cgacctggga
     5701 aaatccgttc aggcacgatt gttatgctag ctatagacga tcatgatcaa gttttagaag
     5761 tcagaaaaat gcaaggggtt acatctttgg caaaatttca ttcattacct gtctatgcgg
     5821 gtgaagatat ccattacatc gatcgttacc atccctcagt tcgagcggaa gatcgtttga
     5881 cacaagcagc tttagaaaat gccagagaag tatacttacg aatagaggca ggaaatgaaa
     5941 aaagtgaaca accttcattg ccttttattg ctatgctcaa taattttcgg atatggaaaa
     6001 gtacgatcaa agaaaaaagg agtgacaaac gatggatatc ataacaaaat ttgctgaggg
     6061 atttatgagg ctgttccaaa caggtgcaga aacattcata agctggatga caggaatcgt
     6121 accagttgtc ttgatgctga tggttgcaat gaatacgctg attgcttttt taggtgaaga
     6181 ccgagtaacg aaagtagcca aattatcagc gaaaaatccg cttactcgtt accttgtgtt
     6241 accgttctta tctgctttta tgttgggaaa tcctatgtca tttacaatgg ctcgtttcct
     6301 tccagaatac tacaaaccaa gctattatgc tgctcaagct caattttgtc atacgagcaa
     6361 tggtgtattc ccccatatta atcctggaga attgtttgta tggatgggga ttgctcaagg
     6421 gatcgaaacc ttagggctaa attcgatgga gctggctatc cgatacttgc ttgtgggact
     6481 gctgatgaac tttattggtg gttggataac tgattttact actggatttg tatgcagaca
     6541 gcaaggaatc gttcttagca aaaaagtaga gctttcagtt gattagagaa aggagagttt
     6601 taaatgtatg gtgatattaa gatcgtaaga ggaaacggcg ggtatggagg tcctttgatt
     6661 attaggccga caaaagataa acacaagttc atctatgtca caggtggagg tgagaggcca
     6721 atgatcgtag ataaaataga agaactgaca ggtatggagt ctatcaatgg gttcaaaaca
     6781 tcaatacctg atagtgaaat cgcgcttgca atcgttgact gtggagggac tcttagatgt
     6841 ggaatttatc ctaaaaaagg gataccaacc atcaatatcg tttccacagg aaaaagtggc
     6901 ccattagcac aatatatcac tgaagatatt tatgtttcag cagtagggtt agaacaaata
     6961 cagccactaa tggaaactga tgataacaaa gaaacagtaa atactgcatc tccagataaa
     7021 aagtacaaat atgatacttc taaaaagata accgagcaaa aagcagagca gcaaaactgg
     7081 atagcaaaaa ttggaatggg cgcgggaaaa gtagttgcta cattcaatca atcagcaaga
     7141 gaagcagtag atacgatgat ccggacagtg atccctttta tggctttcgt ttcccttttg
     7201 attggtgtga tacaaggttc tgggatcggt aatgtatttg ctaacattat ggcaccttta
     7261 gcaggaaatg cagttggatt aacaatcatt ggctttattt gttcactgcc atttttatct
     7321 cctttgcttg gtccaggggc agttattagc caagtgattg gaacattgat cggtgtagag
     7381 attgggaaag gaaatattcc tccccaatta gcattaccgg cactatttgc tatcaatact
     7441 caaaatgcat gtgattttat tccagtcggt ctaggtttgg aagaagcaaa agctgagaca
     7501 gtagaagtag gtgtaccatc agttctttat tcaagatttc ttaacggcat cccacgagtt
     7561 atcattgctt gggtagcaag ttttggatta tatagctg
//
LOCUS       DAYNVV010000097         7398 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.101, whole genome shotgun sequence.
ACCESSION   DAYNVV010000097 DAYNVV010000000
VERSION     DAYNVV010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.101"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(18..923)
                     /gene="xerC"
                     /locus_tag="ACGXWR_002672"
     CDS             complement(18..923)
                     /gene="xerC"
                     /locus_tag="ACGXWR_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HFK0804152.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(1121..2497)
                     /gene="trmFO"
                     /locus_tag="ACGXWR_002673"
     CDS             complement(1121..2497)
                     /gene="trmFO"
                     /locus_tag="ACGXWR_002673"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047151 - tRNA
                     (uracil(54)-C5)-methyltransferase activity,
                     5,10-methylenetetrahydrofolate-dependent [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HFK0804153.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(2466..4544)
                     /gene="topA"
                     /locus_tag="ACGXWR_002674"
     CDS             complement(2466..4544)
                     /gene="topA"
                     /locus_tag="ACGXWR_002674"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HFK0804154.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(4666..5523)
                     /gene="dprA"
                     /locus_tag="ACGXWR_002675"
     CDS             complement(4666..5523)
                     /gene="dprA"
                     /locus_tag="ACGXWR_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HFK0804155.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(5579..6346)
                     /locus_tag="ACGXWR_002676"
     CDS             complement(5579..6346)
                     /locus_tag="ACGXWR_002676"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HFK0804156.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDVRSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(6339..7199)
                     /gene="ylqF"
                     /locus_tag="ACGXWR_002677"
     CDS             complement(6339..7199)
                     /gene="ylqF"
                     /locus_tag="ACGXWR_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HFK0804157.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            complement(7293..>7398)
                     /locus_tag="ACGXWR_002678"
     CDS             complement(7293..>7398)
                     /locus_tag="ACGXWR_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFK0804158.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT         1917 a         1633 c         1296 g         2552 t
ORIGIN      
        1 tgttcttttc cttattttta cgctcttgga tggaaagaac gatagttttt ttgtaaactt
       61 tcttttgtta catgggcata gatctgggta gtcgataaat tggcatgtcc tagcaattct
      121 tggactgtcc gcaaatctgc cccattattt aataaatgag tagcaaatgt atggcgcagc
      181 atgtgaggat ggatatcact atccaaactg ctttttttga tcatttgatt caagacatat
      241 tcaattccag taggcgtgat tggttttcca tgatgattca caaaaacgat atcatgctct
      301 tcgtgatatt ttgtcatcaa tacctggcgg ccttccctga aatattcttg cagagcatct
      361 tgagcaaaag aacctagagg agcatatctc tctttgttcc ctttaccatg gatcaacatg
      421 acctctgaat caaaatcaat gtctgatacc gacaaactgc tacactcact taaacggatg
      481 cctgacccgt aaaggacttc cagtaaagcg cggttcctca aatccaaagg actatctcct
      541 gctacgctgt caaaaagtgc ttgcatttca ttttcataaa aaaaacgtgg cagtctcaaa
      601 tttttctttt tgagatgaac gtaagaaaat ggattttctt ttatcacttc ttctttgaga
      661 agatactgat aaaacgaacg taggctggct atcttgcgac tgatagaatt tctgctatag
      721 ctaggacgat gatcagctaa tgcactcaaa tagacacgaa ccgtaaaata ttccgccttc
      781 agcagatcag cgtctccaga ttcctccaaa aaatgtttga aatggagaat gtcttcttca
      841 tatgcttctt tcgttttttc tgaatatcct ctttcgacaa tcaaataacg caaaaatttt
      901 tgttcccacg tggcttctgt cattttctca ccttcctttt gtcccagaga ataatttagc
      961 acagcgttta taaaaagaca aataaattgt cagaatttaa ccaatatttc taagtttgtt
     1021 cacaattggc gcaattcctc acattttgtt tgagaaattc ttaagaaaaa cgcaagaaaa
     1081 agagcgagac tatccgtctc accctcttca tggagtttcc ttactcattt gggattgcag
     1141 ttttttctaa ttctgttttt attgcctcat tagcttttaa agctcgttgt gcaattgctt
     1201 catatcttgc ttttttgtct cgaatgcgct ctggcagttc aggaaacaga ccatagttgg
     1261 cattcatcgg ttggaaatgt tttccttccg catgagtaat gtagtaagcc atacttccaa
     1321 tagctgtttc ttgtggaaac tcgactggtt ccatttcttt tgctaagcgt gcggcgttga
     1381 ttccagcaag tagtccgctc gctgcacttt caacatagcc ttctacacca gtcatctgac
     1441 ctgcaaagaa cagatcttcg cgtttcgttg attggtaagt cggtttcagc aattctggcg
     1501 aattcataaa gctgtttcgg tgcatcacac catagcgaac gaattcagca ttttctaacc
     1561 caggaatcat ccggaaaaca cgtttttgct cgccccattt caagtgagtc tgaaagccca
     1621 cgatgttgta taaagaagct gcagcattgt cttgacgcag ctggataaca gcataaggac
     1681 gtttgccagt tttaggatct tccaatccaa ctggtttcat aggtccgaaa agcatcgttt
     1741 tgaatcctcg ctgtgccatt acttcaattg gcatacatcc ttcaaaatat ttttctttct
     1801 caaaagattt aagttctgcc acttcggcat tgattagtgc ctcatggaaa gctttgaatt
     1861 cctcttctgt catcggacag ttcaagtaag ctgcttctcc tttgtcatag cgggacttca
     1921 aatatacttt atccatatcg atcgtagctt tgtctacgat tggtgcagct gcatcataga
     1981 aataaaaacc atctgaacca ttgaatgctt tgatgctttc tgctaatgga tgagaagtca
     2041 aaggtcctgt tgctactacg gtgattcctt ccggtatttc agtaatttct tcgtttatca
     2101 ctgttactaa tggatgctct ttgacttttc gggtaattgt ttcagaaaaa gaatcgcggt
     2161 caacagctaa ggcaccacca gctggcactg ctgtttcatc tgccgaagtg attactaccg
     2221 aattcaatcg gcgcatttct tctttcaata accctactgc attagccaaa ctgtttcctc
     2281 ttaatgaatt ggaacatact agttcagcaa aattacttgt gtgatgcgcc tcagtcgatt
     2341 tgactggacg catttcatat aaacggacag ggactcctgc ttgtgcgatc tgccaagcag
     2401 cttcacttcc ggcaagccct gctccaacaa catttaccat tttcaatgaa agaacctctt
     2461 ttctattatt tttggatgtc ttcttcgtaa tctccattta cacagactac ttgtttaccg
     2521 cctttgactt tcttctcgac cagatatccg tcacattttg gacaatttct gcccactggt
     2581 ttatcccaag aagtgaattc acattctggg aaacgggaac aaccatagaa tagtctgttt
     2641 ttcttagatt ttcgttcaat gacttgtcct tcatgacata ctgggcaagt cacaccgatt
     2701 tcttttacga ttggtttcgt attccgacaa tcaggaaaat tactgcaagc ataaaacttc
     2761 ccatatttcc ctaattttat caccatcgga tgtccacaga catcacaatc gaatcctgct
     2821 ggttcatctt tgatttgaat tttttcgatt ttttcttccg cattcgtcag ttctttttca
     2881 aacggtttat agaaacgatc aaccactttg acccacgctt ccgtgccttc ttcaatttta
     2941 tccaaatctc cttccatttc tgctgtgaaa tggatatcga cgatttgagg gaagaattca
     3001 cagattaatg aattgacaat ttctcctagt tcagtcggct caaatctttt ttgtgtcaat
     3061 tttacatagt agcgtctttg gatcgtatca agtgttggtg cataagtgga aggtcgccct
     3121 accccgtttt cttctagtgc acgaatcaac gtagcctcac taaaacgtgc tggtggttga
     3181 gtaaaatgtt gttttggttc aatatcaaca gattggacta catcgccttc ttcaagttct
     3241 ggaagaatat tttctttctc ttctttgccg tcatctctac cttccacata cacttgcatg
     3301 aatcctttga atttgatttt tgaaccgttc gcaatgaaga tgacaccatt ttgttctaat
     3361 gtcactttca ttgtatctaa aatagctggt gtcatctgac tagccacaaa acgtgaccag
     3421 atcaatgtat aaagtttcaa ttgatcttta tctaaatatt gtttgagttc atctggtgta
     3481 cgaagcacac tcgttggacg cacagcttca tgggcatctt gtgcgccttg agcatttttg
     3541 atctttcggt gatcatgtct agaaaattct tttccatacg tatcttcaat aaatgctgcg
     3601 gcctctgctt ttgctgtatc ggcaatccgg gtagaatcag tacgcatgta tgtaatcaag
     3661 ccgactgttc cttgtttacc caaagtgatt ccttcatata attgctgtgc taccatcatg
     3721 gtttttcttg ttcgaaagtt taacttacgg gcagcttctt gttgcaggct acttgtagtg
     3781 aaaggattcg cagggtttct tttgcgctct ttcttttcta cttttttaac ttcgaagtct
     3841 gttccatcaa ttctagcagt gacttctttt acactttgtg catctggtaa tttctttttc
     3901 ttaccgtcga ttccccagaa atttgctttg aatttcttgc gagctttttt aaaattaccg
     3961 tcgatgctcc aatattcttc tggaacaaat tctcggatct ctttttcacg gtcaataata
     4021 atttttaaag cgacagattg gacacgtcct gcacttaacc ctttcttgac cttacgccag
     4081 agaataggac tgatcgaata accaacgatt ctgtctaagg tacgacgagc ttgctgtgca
     4141 tctactaaat ctacatcgat cgttcttggt tccttaaaag ctgctttgac tgcgtctttt
     4201 gtgatttcat tgaagaccac ccgatttttt tctttcagat ccaacccaag taggtacgct
     4261 aaatgccaag caatcgcttc tccttctcta tccgggtcac ttgccaagta aactttttga
     4321 gctttttttg ctgcggcttt caggcttttg atgacatcgc cttttccgcg tatagaaata
     4381 taatggggtt cataattgtt ttcaaaatcg atacccattt tacttttcgg taaatctctt
     4441 atatggccaa cactggccat tactttatag tttcgtccaa gatatttctc aattgtcttg
     4501 gcttttgcag gtgattctac aatcactaaa tatttatacg ccattactga atggactcct
     4561 ttccattgtc gtgttcctac tattaaaaga ggattcatac aaatcgtagc taatcatatc
     4621 cattcagaaa acgtttgtca agaaaagcaa atgaaaagta tggtgttatt ctttaaattc
     4681 tgccaagata tcttcacccg aaaccgtgca aactgcaccg tcttggatca aatgatgaca
     4741 tccggtagaa tgttctgtta aaatatttcc tggaacagaa aaaactgttc ttccaagatc
     4801 caatgcttgc tgtgctgtta tcagagagcc gctttttttc ttggcttcaa agacacatgt
     4861 tcctttagac aaagctgcga taatccgatt tctcattgga aaacaatgct ttttcgggcc
     4921 ggattgagga ggatattcac tcaaaagaag atgatcattt gcaatcacct cttgcaagtc
     4981 acgattttca gcaggataga cttgctctat ccctgttcca atgactgcga ttgtccgtcc
     5041 accatgagag attgctgctt ggtgaccgta tgtatctatc cctttcgcgc agccactgac
     5101 gatcacatat ccagcttcta tcactggttt tagtaaataa taaactgttt ttttggctaa
     5161 agcagaagtg tgtcttccac caacaacgct taacatgtta caagaaagta aagatagatc
     5221 accattataa aacagtacaa ttggcggata ggtcaagtga agcagctgag ggggatattt
     5281 gggatcaaag caagtgataa acgactgttt cgattggatt ttgccccagt tagcgtgaat
     5341 ttcctgccaa cttttgcgaa acagctcccg gtgtttggtt attttaccta tcttaatgat
     5401 gtcttcaaat ccgatttctt tataaggata ctgcatcatc cagttagcaa gtgcccattt
     5461 tccttgacta ctgattcctt ttgtataagc aagtttcaat aaattttctt ctatttgata
     5521 catcataaaa ccgcctttcg tctctctttc taataagata cgtaaaagcg gctgtttttt
     5581 attgtaaata tttttttaca ggtgcaaaac ttttacgatg gattggcgta attccttgtc
     5641 gttcaagtcc ttctaagtgt tcctttgttc cataacctgc attatgcgag aaaccatatc
     5701 caggataaag cacgtcatat tctttcatca attggtctcg atatacttta gcaatgatac
     5761 ttgcagcagc aatcgacaca gatcgtacat cccctttgat tattttttcc tgctgaatag
     5821 gcaaatccaa ggtcatcgca tcgatcaaca aatagcttgg tacaatggac aatttttcta
     5881 ctgcttggat catcgctaat ttacttgctt cataaatatt cacatcatcg attgtctgct
     5941 gatcaacgat cccgatcccg attgccaggg ctttttcttg aacttgttga taaagaagtt
     6001 ctcgcttttt ctctgataat tgtttggagt cattcagccc taatatgatc tcatttttcg
     6061 gcaagataac tgcagctgcc acgacaggtc cagctaatgg tcctcttcct acttcatcaa
     6121 tgccggcaat ccattggtga ccttgtgcgt acccttgctt ttcaaagcaa aacatttctt
     6181 catatttttc cttaattaat gcttcctttt tcaatcgtcg ttcaaaagaa gccagtgctt
     6241 gctgcacgcc tttgcgtgga tcatttctta atgattctag tgtaggatca tctattctct
     6301 gtatgctttt caatcgttct ttgatacttt ggatggattc agtcatcact tttttgctcc
     6361 atttcttcgc aacgatccag tgtgtatcgt ccaagttttc cttgacgaat atcatgcacg
     6421 actaattcgc tgccacgatc atagtcttct ttatacccac gttttgctgt aatatccatc
     6481 agtaattccg gtgccaattt ttcttcttgc tcgattgata aaccataacg atcgctgatt
     6541 cttcctgaat aatatcgggc aaaaaagtct aatccgtaaa tcgctaaatc atctaaatgg
     6601 acaagctggt ctttgatcgc gcctgtcagc gctagttttt tgccgatttc ttcatcttca
     6661 aatttgggcc ataaaatccc tggtgtgtct aacaattcca actcattacc taaacgaagc
     6721 cactgctgac cttttgttac gccaggctta tttcctgtct gtgcaatttt cttgcctact
     6781 agtcgattca tcaacgtaga tttcccaaca tttggaatac ctaagaccat tgcccgaata
     6841 gcgcgaggct tgatcccccg agcagcatct cttgcccgtt tttctttcaa tgcttcttta
     6901 gccgcaggta ctagaccttt aattccttta ctttcttgtg ccgtgatagc taatgcaaga
     6961 tggccttgtt tacgaaaata ttcttgccac agctttgtct gttgtggatc tgccagatcc
     7021 gctttattca ataaaacaag gcgaggtttt tgctgaatga tctgatctag cattggatta
     7081 cgagaagata aaggtaatcg tgcgtctacc aattcaaata cgatgtccac atatttcatt
     7141 ttttcagaaa cttctcgtcg ggcttttgcc atatgtcccg gaaaccattg gatggtcatt
     7201 gttctctcca ttcctttcat accggaatat tccccggctt tacttgtttt tttctttttc
     7261 aatataaatt cactttttta ttatcttaat tgtcaaatta agttagacag atcatcaata
     7321 cttacgtaac tcaaaaatac ttccaaaggt gttcgataat ccagtgattt tctaggaata
     7381 ttatttcgtt tagatgcg
//
LOCUS       DAYNVV010000098         7323 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.102, whole genome shotgun sequence.
ACCESSION   DAYNVV010000098 DAYNVV010000000
VERSION     DAYNVV010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.102"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..456
                     /locus_tag="ACGXWR_002679"
     CDS             <1..456
                     /locus_tag="ACGXWR_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804159.1"
                     /translation="AERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQEH
                     KNTVETAENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGKS
                     YGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            517..1977
                     /locus_tag="ACGXWR_002680"
     CDS             517..1977
                     /locus_tag="ACGXWR_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFK0804160.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFIPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            1988..4097
                     /locus_tag="ACGXWR_002681"
                     /pseudo
     CDS             1988..4097
                     /locus_tag="ACGXWR_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
     gene            4113..4262
                     /locus_tag="ACGXWR_002682"
     CDS             4113..4262
                     /locus_tag="ACGXWR_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804161.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            4343..4939
                     /locus_tag="ACGXWR_002683"
     CDS             4343..4939
                     /locus_tag="ACGXWR_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFK0804162.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            4952..5851
                     /locus_tag="ACGXWR_002684"
     CDS             4952..5851
                     /locus_tag="ACGXWR_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFK0804163.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNEIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKERKLAYQRHQQMNREMER"
     gene            5854..6339
                     /gene="ssb"
                     /locus_tag="ACGXWR_002685"
                     /pseudo
     CDS             5854..6339
                     /gene="ssb"
                     /locus_tag="ACGXWR_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            6361..6618
                     /locus_tag="ACGXWR_002686"
     CDS             6361..6618
                     /locus_tag="ACGXWR_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804164.1"
                     /translation="MAKKISLTMDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVF
                     VYLVCSYLLKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(6777..6899)
                     /locus_tag="ACGXWR_002687"
     CDS             complement(6777..6899)
                     /locus_tag="ACGXWR_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HFK0804165.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            7054..7313
                     /locus_tag="ACGXWR_002688"
                     /pseudo
     CDS             7054..7313
                     /locus_tag="ACGXWR_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328871.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         2665 a         1257 c         1543 g         1858 t
ORIGIN      
        1 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
       61 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
      121 aagcaggagc ataaaaatac tgtagaaacg gcagagaata agaatattgt gcccgttggt
      181 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
      241 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtgat tttaaaagga
      301 aaaagttatg gaaaagagat tcaaacggcg ttaccttcag aagaatttgc gctaggaaat
      361 ccattccgat tttcacttga aacagtgtca gaagtggcca aacgaaaaaa tgaaatctat
      421 tatgaacaac aattgtcaca aaaagaacgc gtataaaaca agtaaaaaag actatctgaa
      481 aaacggatag tcttttttct tttgggaggt ttgaaaatga ccgaaaaaaa aatgagtctt
      541 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
      601 gtcaataaag gacgagacta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
      661 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
      721 ctttttttca tagacaaaga gatccaagac tctaagcaac aatttaaagc agccactgat
      781 tttattctaa agaatgaaga caaaacagaa cgagtggaaa atcttcattt tgaaacagaa
      841 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
      901 aaggaagaac gaaaactacc agagtggctg attgattatg cagaaaaaga agggttgatt
      961 gccgaactaa agccaaaata tgaacggcaa aatttcttag ttcgagacga tcgtttagat
     1021 catgcggtcg cctttttatg gaaagatcca cagacaaaag agacagtagg ggcgagttat
     1081 caaggaacgt tcattgatta tgaacgtttt ggtgagagag gcacatataa gcatatagat
     1141 aaaaattcga cagcgaatca tggctttaac ctaaagatcg gtgaccctaa gcagttaaaa
     1201 ttttttgaga gtagtattga tttacttagc tatgctgcac tgaatcgtga tcagttaaac
     1261 gatacgtggt tagtctctat ggaagggtta aaacaccatg tgatcagtca ttattttggt
     1321 gaggcagtat ctgaattgag aaagaaacaa gcctttcctc aatccatcga gatttgtgtg
     1381 gataatgacc gtgcaggaca tattttctac gaaaaagaac aattaatggg cgcagtcgat
     1441 ccatttacga atcagaaagt acgttgtgaa cgaggaatcg ctaatgattg gcaagtgcca
     1501 aaagaataca aaatcattta tgaagaagtc gcaaaagaag aaaaggtcac accagaagct
     1561 attatggcca tacacaagac agaaaacaat ctgcaattaa cgaaccaact ggtttccgct
     1621 cacaaagtaa atgcgttttt tggccagcag ctttctgtta acgattcaat agaagccatt
     1681 aatttgaaag atatttgtag agaagtcgca aaagaattaa aagtttgtga acgcgtggat
     1741 ggtacgtacg attttgatcg tttttatcaa gaaaaagggg atattaatgc gcagattctt
     1801 ttctcttata aagcagaaca atactacaaa ggctataaaa atcatgaaca tgaatttata
     1861 cctgaagtaa aaaaggattg gaatgatcaa ttgaagcatg agatccagca acaagaaatc
     1921 agaaagcaaa aacgtgccat gttgtttcaa caaggcagac aacaagaaag ggagtgaaat
     1981 cgtcatgatg aaaaccgtta ttttagcaga aaagccgtca caagcgaaag cttatgccga
     2041 tagcttctct aaagccactc gaaaagacgg gtattttgaa atccaagatc gattgtttcc
     2101 tggtgaaact gtgatcacgt atggttttgg tcatttagtc gaattagatt cgcccgatat
     2161 gtacgatgaa aattggaaac aatggtcatt agaacatttg cctattttcc ctacacatta
     2221 tcactatcat gttcctaaag ataagaaaaa gcaattcaag gtggtgaaac agcaacttca
     2281 atcggccgac accattatta ttgcgacaga tagcgatcgt gaaggggaac tgatcgcttg
     2341 gacgatcatt caacaagtag gcgccgatca aggaaaaacc tttaaaagac tttggatcaa
     2401 ctccttagaa aaagaagcca tttatcaggg attccagcag ttacgagacg caaaagagac
     2461 ctatccaaaa tttgaagaag cacaagcacg tcagatcgcc gattggttaa ttgggatgaa
     2521 cggtagccca ctgtatagtt tactcttgca gcaaaaaggc ataccaggaa gcttttcctt
     2581 aggcagagtc caaaccccaa cgctttacat gatttatcaa ttgcaggaaa agattagaaa
     2641 tttcaagaaa gaaccttatt ttgaaggaaa atccgaagta atcgctcaaa atggcgcatt
     2701 tgatgcgaag cttgatccga atgaaaccca agcgacgcaa gaagcatttg aagattattt
     2761 aaaagaaaag ggggttcaat tgggaaaaca gccaggcatg attcgccaag ttgaaaccga
     2821 gaaaaaaagc gcggcaagtc cacgtctttt ttctctatcc agccttcagt ctaaaatgaa
     2881 tcagctcatg aaagctagtg ccaaagacac tttggaagcc atgcaaggct tgtatgaagg
     2941 gaaatatcta agctatccac gaacagacac cccttatatt acggaagggg agtatgcgta
     3001 tttgttggat catttagatg aatacaagca ttttttaaag gccgaatcaa tcccaacccc
     3061 tattcatacg ccgaatagtc ggtatgtgaa taacaagaaa gtccaggaac attacgcgat
     3121 cattcctaca aaaacggtta tgacagcagc ggcttttgaa caactaagtc cactgcagca
     3181 ggctatttat gaacaagtgt taaaaacaac ggtggccatg tttgcggaaa agtataccta
     3241 tgaagaaaca acgatcttga cgcaagttca gcagcttcag ttaaaggcaa tcgaaaaggt
     3301 gccgctagat ctaggttgga agaagttatt tggaaaagag agcgacggaa aagagaagga
     3361 agaagagccg ctacttccta aagtgacaaa aggagaaatg gtgacggtgg atctacaagt
     3421 tcttgaaaaa gaaaccaagc caccacaacc ttataccgaa ggtacgttga tcactgcaat
     3481 gaaaacagct gggaaaaccg tggatagtga agaagcgcaa tccatattga aagaagtgga
     3541 aggaatcggt acagaagcga cacgggcgaa tattattgaa accttgaaac aaaaggaata
     3601 tatcaaggta gagaaaaata agctcgtggt gacgaataaa gggattttgc tttgccaagc
     3661 cgtggaaaaa gagccgctgc ttacgagcgc cgaaatgacc gccaaatggg aaagctactt
     3721 gttaaagatc ggtgaacgaa aaggaacaca aaccactttt ctagccaata tccaaaaatt
     3781 tgtctctcac ttattggaag tcgtaccagg gcaaatccaa tccactgatt ttggatcgac
     3841 gttacaagaa gtgaaagcag ccagtgaaaa gcaagaagcc gcgcgtcatt taggaatttg
     3901 tccaaaatgc caggaacaag aagtcttact ctatcaaaag gtggcagctt gtacgtctga
     3961 agcctgtgat tttaaaaggt cagaagggtt catttgaagc aacgattgtt ttaaaagaag
     4021 acttcactac aggctttgaa ttttctgaaa agaaaaaaac gaacttcaag aaaagaacac
     4081 gccgcactgc aaaataatgg agggttaatc ttatgcgtaa taccacacac aaacaacaag
     4141 aaatcgaaaa tcaaaaagcc aaaattcgtt cagaacagga aaaaatgcgt gccagcaaac
     4201 gaagactgca gcaattgaag aaccagcaga ggattcaaaa agaaatcgaa ttagatcgat
     4261 aaaatcttcc taactattgt atacgtataa acttatgtta tactgttttt ataagtttat
     4321 acgtatacaa aggagggaga aaatgacaaa agcaatggta tacaagctgc tagaagaatt
     4381 taatggaact ttggctttga aggatgccaa aaaagcgggc atttctcctg taacgatcaa
     4441 acgtatggta gatcgagggg agctggatcg agagtatcca ggttttttca ccttacctgg
     4501 tcaatttcct gatgaattgt ttatggcgca aaaaaaatat gaacgcggca ttatttcaca
     4561 tattaccgcg ttagatttgt atgatttaac agatatgatc cctagacaga tcgatctgac
     4621 tgtaccttac ggttatcacg tttctgaaaa aggattgaag gaattcgcag ttgagctaca
     4681 ctatacaaaa gcggaatggt atgaattagg taagattgaa ataaaaagtc gctatgggaa
     4741 tcctattata gcttatgatc cagaaagaac tttatgtgac atttggaatc cctggtatac
     4801 cgttgaggat gaaatcaaag taaaagcaat caaaaactat atggagtcgg acagaaaaaa
     4861 tcttagaaaa ttgaatgagt atcgacgaat tttaccaaca gacaaaacga tgcgttctta
     4921 tattatggct ttaaattaaa ggagaagata catgacacct acgcagttaa aagcaaaagt
     4981 gaagaatatt tctagagaaa aagaagttga tccgcagctt gttttaagac attttatgat
     5041 ggaaaaattc ttggaaaaaa tctcagagtc tccttatcgt gaaaattttg tgttaaaagg
     5101 cggcttcttg attggctcaa agtatggcat tgaaaatcgc acaaccaaag atattgatac
     5161 gactttacgg gaaatgaaag taaccaaaga aacattaaca acggttctaa acgaaatttt
     5221 ttcaacgccg acgaaagaag gcattcaatt tgagattcaa ggaatgaaag aaacgagaga
     5281 agccgattac tatccaggat ttagcttacg tgtgctggca catttggaaa acatgcggcc
     5341 agattttaag gtagatgtga ctacaggtga ctcgatctat cctgcaacga tcactcacag
     5401 tcataaattg atgtttgagg atcgaacgat tcctttggaa tcctatccta cagaacaaat
     5461 tattgctgaa aaattaagtg caacctttga ttttttaaca gataattcga gaggaaaaga
     5521 tttttatgat ctctatacta ttcctaaaat ggagaagatc gatgagaaga ccttgaaaga
     5581 tagtgtgaga aatacattta cacgtcgagg aaaaactgat ccgttaaaga tatactatga
     5641 aaaggatatg gatgtactga aaaatagtca cgagctaaaa gatacctgga agaaatatca
     5701 aaaaagcaat ccttatgctg cgtcgatcac gtacgatgag acaatggatt cgattagtaa
     5761 tttgatggaa aaagtgattc acgtcgaaga aaaagagcga aaactagctt atcaaagaca
     5821 ccaacagatg aatagagaaa tggagagata aagatgatta ataatgtgac attagtagga
     5881 cgcttaacca aagatcctga tttacgttat accgcaagtg gtactgcagt agcgactttt
     5941 accctagccg tcaaccgaaa tttcacgaat caaaacggca attgagaagc cgattttatt
     6001 aactgcgtga tttggcgcaa accagcagaa acaatggcga cattagctaa aaaaggtagc
     6061 ttgattggtg tagttgggcg gattcaaacg cggacttacg acaaccagca aggacaacgt
     6121 gtatatgtga ctgaagttgt agcagataac tttcaactat tagaaagtaa agcagcgaca
     6181 gagagccgtg cgcacgctga tcaatcgtcc accagtccaa gcaccgccac ctttgaacaa
     6241 cggaatacag cgacgcctaa caacaatgga ttgaacgctt cacagaatcc atttggtgga
     6301 caatcaatcg atattagcga tgatgatcta ccgttttagt ttgagaaaga aggagtaagc
     6361 atggcaaaaa aaattagtct gacgatggat ctattgatac ccgtaattgc atttatagac
     6421 gggatttctt tgggcgtcac tgaaaatcct ttggtaaata gaattgcgaa aggatcacta
     6481 tttcttgtat tcgtgtatct tgtctgttct tatcttttaa aaagagcagg aaaggataat
     6541 tccttttggc gattgactaa agtcacagta gcagcgacag ctgttatact tacggctatt
     6601 ctaccgcttt atatgtagag ttaacgggaa atcgttgaac ttcttgcgaa atattgctat
     6661 aatgaacatg aaaaagagga gttgcgctaa caacccctca ttaacagcac cgattaaaga
     6721 acggtggcag aatattagtt atttggaaat aaccgctgac ctgctaaagt agacggttat
     6781 ttctttttgt catttttaag catatttaca atcaaactaa tcaaagcaat ggtaaacata
     6841 ccaaaaccaa gaatggtttg aattgtctca tatgcggaca aaaggcttac tcctttcata
     6901 gattttagca cttacattca taagcaccac cacctttcca gaagtcgcca ccgtcttcaa
     6961 actttactgt cttgactatt atagcatatc taaaatcgaa taaaaattct caattttagc
     7021 tgtttttgct ataattttag cgaggtgatc gtgatggaac aatatattgg tttactcgat
     7081 aaattagggt gatcaagaca cagccattgc ttgtgcgatt tacattacgc acgagtcatg
     7141 aaccaatcaa ttgtgtagtg gccaatatag aaatagcgga taaattgctg attttggaag
     7201 aaggcaagta tactatttca gtgacaggtc acttcaataa acgaaatcaa ctagtcattg
     7261 aatcaatgca aattagaaac cctgatcatt ttacgagatt aatgggcata taaataaaag
     7321 aag
//
LOCUS       DAYNVV010000099         6130 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.103, whole genome shotgun sequence.
ACCESSION   DAYNVV010000099 DAYNVV010000000
VERSION     DAYNVV010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6130
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.103"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..413
                     /locus_tag="ACGXWR_002689"
     CDS             <1..413
                     /locus_tag="ACGXWR_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804166.1"
                     /translation="LIGGYFLLNLDSVNSNAQIKDQRVAEHNNKKMSLTKNIYSMSDE
                     ELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSELVSYKQNHRQFIDVN
                     TDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            427..1116
                     /locus_tag="ACGXWR_002690"
     CDS             427..1116
                     /locus_tag="ACGXWR_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804167.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1241..3592
                     /locus_tag="ACGXWR_002691"
     CDS             1241..3592
                     /locus_tag="ACGXWR_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="HFK0804168.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3672..4067
                     /locus_tag="ACGXWR_002692"
     CDS             3672..4067
                     /locus_tag="ACGXWR_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804169.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4392..5009
                     /locus_tag="ACGXWR_002693"
     CDS             4392..5009
                     /locus_tag="ACGXWR_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFK0804170.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5050..5349
                     /locus_tag="ACGXWR_002694"
     CDS             5050..5349
                     /locus_tag="ACGXWR_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HFK0804171.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5383..5550
                     /locus_tag="ACGXWR_002695"
     CDS             5383..5550
                     /locus_tag="ACGXWR_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFK0804172.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5595..6065)
                     /locus_tag="ACGXWR_002696"
     CDS             complement(5595..6065)
                     /locus_tag="ACGXWR_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFK0804173.1"
                     /translation="MEFREGAFDFQTSQQNPSLDRLGRDYEDIKNTVAFMKQKKVALK
                     ILDAQFLDFNTGNELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKG
                     RPIEYSINSTDPQKRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT         2102 a          855 c         1235 g         1938 t
ORIGIN      
        1 tattaattgg gggctatttt cttttgaatt tagattctgt taattcaaac gctcaaataa
       61 aagatcaaag agtagctgaa cataataata aaaaaatgag tttgaccaaa aatatctatt
      121 ctatgtcaga tgaagaattg tataaagaat ttggtgattt atccggggaa cagttagaag
      181 aaagtattcc aggaattagt gactcagata aaattgttgt cttgtctgct ggtgggcaat
      241 taatgggaga tggcaaatcc gaattagtta gttataaaca aaatcacaga cagtttattg
      301 atgttaatac tgattccaac gctatttcga ttaaggatct aaaagagctt ttaaatagta
      361 aaagaaatga attaaagcag ataaaagaaa ctaattcagt ggaattagag taaaggaaga
      421 ttcattatga aaaagatttt tggtgtttct gttgggctac ttatgatgtt aacatttgga
      481 aatgcagtat atgctgctga gaaagaagtt atttcagatc cagagcagta cgcctcacga
      541 tactttgctg attttgaaga agaagataaa gtacttgcat tgccagaagg tggtttttta
      601 aaaggggaag ctaaaattgt atctatggat aatccagata taattcaagg ttcatataat
      661 tcagaaactg atcctgcttc agtttcagtg acagaagcaa aaaaaattgt tgctgaaaaa
      721 ttcaaaaatg atattgaaac tactccaatt atgcctcgag gagcatttcc acccgatgtt
      781 ggtactagcg gacaccttct tgtactagca ggaggaggaa gctataaatc acagccattt
      841 agtggtgcgg gatggcgttt tggaggtatg ggtgtaaaac cagctgatgg tacaggcaac
      901 tttttacgtt ggaaatccta cattgacgat ggaagagtag gaaatgtaaa tcaagccaac
      961 gcaactaaat ctggttctat tcaaggaatg gcattgtatg ctcgtgaagg attcaaatac
     1021 tttgcaccaa acgggcctgg ttggacaatg aatataggta tttattacac ttataatcct
     1081 gttgcaggta cgtattatgt tgttcaaaat atttaataaa acagcacaaa gagatttctt
     1141 tgtgctgttt tattattttt agttgttgac aaacactaaa atataaaata taatcaacac
     1201 ataaacgaac gtatgttcgg caagaaagca ggggattttt atggatgaga tggttttaag
     1261 tactcagaaa tggctaaaca agaaatacag taatgttaca gggtttgata aggttccaga
     1321 aaatgggcga acagggtggc ctacaatcta tggacttatt gaaggactac aagtagaact
     1381 tggtattact aatctagtag ctaattttgg acctaccact gaaaaaatgt acgataatca
     1441 ggttactcct aaatggggca aaaatctacc taaaaatatt gtatttctta ttcaaggtgc
     1501 cttttggtgt aaggggatta atccaggtgg cttcgatggg gtatatactc catatttaga
     1561 tactgctgta aaagagttgc agactgatgc agggtttaat ggaagcgctg taactggagt
     1621 tttggatgcg aaatgggcca aagcgttatt tgatatgagt gcttttgttc ttgttcccgg
     1681 cggagatagt aaaattagaa aaatgcagca atggttaaat gtaaattatt tagaatacac
     1741 gggaataatg ccttgtgatg gtatttatca aagaaattca aatcaagcat taatttttgc
     1801 attacaagct gaactaggat attctcccag tgaagcaaca gggtcttatg gtaatgggac
     1861 aactagtaaa acttatcctg tgtctgaagg taactcggga aactatgtaa gaataattca
     1921 atatggatta tatgttaatg gttattttga agacggtaca ttcgatggta ttttcactaa
     1981 atatatgggt ttagaagtac tggcattccg aaaatttatg gtattgcctg aatatactga
     2041 aatagcagat gttgttgtaa taaaaggact attgtctagc gctggagata ttagaagatc
     2101 tgcagatggc gcagatactt ctacgcaatt aactagatct caaatccaaa cattggttga
     2161 taatgatata aaaatagttg gtagatatct tactggtact gttggaattg gaaaagatga
     2221 acgaaataag tatctaacta cagaggaatt gaataatatt ttttctaaaa atttatctgt
     2281 gtttcctatc tatcaagatg gaggtgcagc attagcttat tttacttatg atcgtggctt
     2341 atcagatggt aagaaggcta tagatgcagc aaaaaatcta aatataccat taacaacagt
     2401 tatttatttt gctgttgatc tagacatgtt aggggaagaa attcttgcat atgctggaga
     2461 atattttaag ggggtatctg ctgtaatgtc atatagcggg tatcaaacgg gtgtttacgg
     2521 aacaagaaat gtttgttctc aaataatcaa taacgggtat gcttcgtttg catttgtttc
     2581 agatatgtcg actggttata gtgggaattt aggttttcct atgcctagac aatggtcttt
     2641 tgatcaattt gttgaattta ccataggaag tggcaacgga gctgttggta tcgatttaat
     2701 cgctacatcg ggtagagata gcggatttaa tgagttatca aatgatacta ataatgataa
     2761 ttacattgcc aaatacaatc agaaggttat aaatcagatg gtacgtgcgt atcaatatct
     2821 atcacaagct ggtcttgata atccttggaa ccctcatttg acattttata gatatgtaaa
     2881 ttattctggt ttgtcatggg acatcatttc ttctcctgta acagagcatg atagaaaaat
     2941 ttatgatgaa tataggaata aattaactaa tagcgagggc ctgtataatt attttataga
     3001 tcctaatact ggttcaataa taggtttgcc tcacttaatt gtgacgttac aatcacagat
     3061 gtttctagcc gacacaatca atgatagtgt ttctgacttt gcaggttggt taggagattt
     3121 aatgacttgc tggggtgaag ttaagaaatt aggaatacaa atggagcaag gtgtatttgc
     3181 attagtaggt acggctgcag gtggaacatt tagtctagaa gatttatacc aagatgttga
     3241 cgcggtaaat gtttatacct tagcaaaaag aaattctgat tcaacagctt tatcggcttt
     3301 aaaaacgtac tattgtgata agggtgctat tgatagattt aatcaatttg ttaagaacag
     3361 atttggttct tcagataaaa tcgcttcagt aacaaatagt ttattagaaa atgacgaaac
     3421 agttgatatc ttaggtgtag ggataatttc atttttcatt gataaaatag ttaataattc
     3481 acttgggaca gattttactt atcttgattt tattggagat gaggggaaag ttgcaaatgg
     3541 attttctgaa aaaattattc aatttcaaga aaatagaagt aaacttaatt aagaatcgtt
     3601 tactatttaa acagtgtcct tttccttttt aaatatatac gataaaataa gtatatgaat
     3661 tgtaaaagga catgatgatt atggaagaaa tagaatggaa taatctgact caaaataata
     3721 aaaataattc tggatgtgga attatcttta tgtttgttat agttttggga atagtagtac
     3781 ttttaataac tgtcaagata gtagattact ttgcgaatac tcctgaagaa caaatacaga
     3841 gaaaacttcc tgagtttgaa agagtaccac cttatgatcc aagagataat tcatttcaag
     3901 taaaaaaatt aaaagagtct ccaaatgaaa tgtggtttga agttacagtt gaatcaagcg
     3961 acttcaaaga aaaaaagaaa gaatacaatt atattgtaaa ggcaaaagta tcaaaaagat
     4021 ttatttttaa ccctaaatta gaaatatata gtgttgtaat agaataatag tgttaaaaaa
     4081 attgtaaaag ttaaagaagt caaattctga tgtgaaaaat aaaatatacc atggaagaca
     4141 taaaagaaaa actggataac tagtttattt aatggcagac cgttaaggcc tgccattttt
     4201 atgtatttta gcggaataaa tataatcatg cgggagtgta aacttactgt ttcaaaaagt
     4261 atactttttg acatgccttg attttctttg tttatgtatg gcataataac cacataatac
     4321 aatttgaaac gtttctgatt taatctgatt gttttgaaac aattttagtg aaaaaagggt
     4381 agataaaaac gatgagaaaa tttttttata tccgggtcag tagttatgat caatcgatcg
     4441 aacgacaact gatttccgcg aaggaattag gaatccctga agaatatata tttgtagaaa
     4501 aagccagcgg caaagatttt aaacgccctg aatatcaatt aatgaaacgg atgtttcgaa
     4561 aaggagattt actctatcta caatcattag atagactagg cagaaataaa caaatgattt
     4621 tagaagaatg gcgagaatta actaaggaaa agcagattga tatttctgtg ttagacatgc
     4681 ctctgttaga tactgctagt tacaagcaac tagatgggtt agagacgctt atctctgact
     4741 taattctgca attactcagc tatatggccg aagacgagcg gaaacgaatt aatagccggc
     4801 aaagagaagg cgtagaagct gcgaaacaaa agggtgtaaa attcggcaga aagaaaattg
     4861 ctttacctcc tgaatttcct gcgatctatt ctgactggaa agcaggaaag ataactgcag
     4921 tctatgctat ggatcaattg ggcatgaaac gaaatacctt ttatcgacgg gtgaaagaat
     4981 atgaacatac cttgcaccac ttttcttgat agatataaca gctattagac gggaagggag
     5041 agtttgaaaa tggacttaac gaatcaaagg gtcgttttta ctggaacgct gcagcaaatg
     5101 acacgaaccc aagccatcgg tttggttcac tctttaaacg gccattgtca atcaagtgtt
     5161 acttcaaaaa caaatttcct ggtttgtggt cagtattcta agtcgttgtt tgatgattct
     5221 ctctatacaa aaaaggaaca aaccgcgcgg gacttgattg cgttaggtca tgagattacc
     5281 attttatcag aagtcgaatt ttatgcgtta attagtcaac agttgaaaga atggcaacgg
     5341 tatttataat cgttagtaaa atttacaagg aggaaaattt ttatgaagcg aaaatcttat
     5401 gatcgttggg gcattgaaat aactagtttt aatcgaaata ttgcttttca cgtggagtgt
     5461 gactgtgggg aattagcaaa aagtgtttat caaaaaaatt acttttactg tcctaaatgc
     5521 catcgccgat acggggtaca tggaacatag aaacgaaata gtgcggtaga aaagcgaatg
     5581 aatgtagtat atttctacaa atcattcgct ttctttattt tataaatagt tggtcgagag
     5641 atcccgtttt cttttgcaat ctctgcaact ggaatgcctt gctttaacat gtccaccacg
     5701 gttttaaaaa ctaagcgttt ttgcggatct gttgagttaa tagaatactc gattggtcgt
     5761 cccttatatc ggccggcttt ttgagccaat aatactcctt gccgctgacg ttcacgaatt
     5821 ttctcacgct cgttttgtgc aatataactt agcagtgata aaaacatatc gaacatagcg
     5881 gtatccagga gttcatttcc agtattaaaa tctaaaaact gtgcatctaa tatttttaac
     5941 gctacttttt tctgtttcat aaaagcaact gtatttttta tatcttcata atctcttcct
     6001 aaacgatcta gtgatgggtt ctgttgcgaa gtttgaaaat caaacgcgcc ctctctgaac
     6061 tccaaatatc ttaggctgtt attcccatta ataccttgat ttcagtagac accgaaaagc
     6121 cgaagagcgt
//
LOCUS       DAYNVV010000100         6128 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.104, whole genome shotgun sequence.
ACCESSION   DAYNVV010000100 DAYNVV010000000
VERSION     DAYNVV010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6128
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.104"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            196..921
                     /locus_tag="ACGXWR_002697"
     CDS             196..921
                     /locus_tag="ACGXWR_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804174.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            911..1420
                     /locus_tag="ACGXWR_002698"
     CDS             911..1420
                     /locus_tag="ACGXWR_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804175.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(1490..2938)
                     /locus_tag="ACGXWR_002699"
     CDS             complement(1490..2938)
                     /locus_tag="ACGXWR_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFK0804176.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(2938..3654)
                     /locus_tag="ACGXWR_002700"
     CDS             complement(2938..3654)
                     /locus_tag="ACGXWR_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HFK0804177.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLAAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            complement(3635..3985)
                     /locus_tag="ACGXWR_002701"
     CDS             complement(3635..3985)
                     /locus_tag="ACGXWR_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFK0804178.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            4129..4902
                     /locus_tag="ACGXWR_002702"
     CDS             4129..4902
                     /locus_tag="ACGXWR_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFK0804179.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            5073..5439
                     /gene="ssrA"
                     /locus_tag="ACGXWR_002703"
     tmRNA           5073..5439
                     /gene="ssrA"
                     /locus_tag="ACGXWR_002703"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(5744..>6128)
                     /locus_tag="ACGXWR_002704"
     CDS             complement(5744..>6128)
                     /locus_tag="ACGXWR_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFK0804180.1"
                     /translation="LKPEGRKAVDIENSINEWLQSVLKNLFKSITFDCGKEFSNWKSI
                     SNTNDIDIYFADPGTPSQRGLNEHSNGLLRKDGLPKEMDFHQVNQGFISSVASKRNHI
                     PRKSLNYQTPLEVFLSYVNGKFCLA"
BASE COUNT         1775 a         1189 c         1071 g         2093 t
ORIGIN      
        1 aaaattattg tcgctgctcc tcttttcgaa taaacagtgt tcaaaagctt gcatctacgg
       61 taatagaata gggcagcttc ttcacaacct cttgcttttt acaaaatatt ttctggtttt
      121 aattcgtgat ttcactaaag gaatttcata ctttattcat attcattttc tatacttttt
      181 atagaggtga aaagtatgaa aataatccgc tatgctactg ctcgattaat ttattacaaa
      241 aagcagacaa tactctattg tttattttca agcttttctg cttttttatt gatagcatgc
      301 ctgactcttt accattcgca atcggcttta gccaatcaag tccaagatcg gctttcattt
      361 attggcgctt ctgcatctac agagcttctt ccggctttag aattagctag ccgattttat
      421 ataaaaggca tattcagttt attttttcta tttgccttcc tttttatctt tttcttttac
      481 tattcagtca ggcaaaacaa gcaggaattg atcaattggc gcctgactgg tctttctaaa
      541 accaaattat tcctttttat tttctggcag ctgttctttc ctctctttct ttgttgtatc
      601 ttggttttat tgtggatcgt cagcttccag tcagtttatg aagcgcttct tcaaaggatc
      661 aattttcttg tcttaaagac tactgaactg ccagatatcc gtgatatctt gacttcggta
      721 agcggactta caattccgat ggatcaacag acttttttta ccatcgattt ccaaaatgat
      781 ctttttttca cagatatact taagggattt gcccaaactc ttattgggct cagtggatgc
      841 tgtctcattc ttagtctatt ccctttcact ttttttatcc atcatttgca aagtaggagg
      901 cctggacgta atgaaacctg aatatttgat tcatgctgaa cacttgaccg ttattttgtg
      961 tcctctcgaa aaacagcata aaatattgga gcacttgaaa aaagaggttc ttgttgcaaa
     1021 actggataat tttgcgatca tccaaaaaaa ttggccgatg tttccttatc tgaatcttaa
     1081 agaccatgtc ctgttggatg taccggaaaa agaaatcaaa caagatcgtt tggcctatca
     1141 agaaaaactt gatatctctc cttccttgct taattgtgcg gcagctgagt tgacgtcttt
     1201 tgaaaaagta aagctgcaat tacttcatgc cttgctttcc aagcgaaaca atattgttat
     1261 tgaagataca tttgatgaac ttagtgtatt ggagatccaa gagctactcc acttgctttc
     1321 ttatttagct catgaagaaa atcaaggtat cttactcttt actcatgatg ctactattgc
     1381 tcaaagtcct tatattgatc gtttagagcc cgcgggctaa atcaatcatt ttatagtaaa
     1441 aacaagcggt atagaagatc gattcatgat cttttatacc gcttgttttt tactcttttt
     1501 tgatttctac gtcaggcaaa cgaacagcga attttgttcc ttttcctagt tcgctttcta
     1561 cttctaattt tcctttatgc aagcgtacaa gttgctgcac gattggtaaa cctaatcctg
     1621 attcaccata ttttgtattt tttcttgaag gatctacttt ataataacga tcccagatac
     1681 ttttcatttg ttgttcagac attccaattc ccgtatcttc aatcgtgatg atcgtttcaa
     1741 gatagccttt ttctaaagta atcgtgattt ggccgttttc agtaaactgt atcgcgtttt
     1801 gaataatatt gaccatgatt tggacaaatc ggtcataatc agcgtaaaca tcaatatcat
     1861 caacggcttt caatgtcaat gtatctcctg ctgcttctgc tttagcttct aactgtgcaa
     1921 caatattttt caatgtttct gttccattga attttttaat gaccatactg atttgattcg
     1981 tacggatttt ttcataatcc aagttttcat tcaccaaacg gatcagacgc tctgtttcat
     2041 ttttcatcaa tttaatcgcg ttttctcgct gattttcagg gattgcattg tattctaacc
     2101 cttccagaag tccgttgatt gtcgtaagag gtgttctcat ctcgtgagaa gcatctgcca
     2161 taaattgtct tcgacgattt tcttgttctt caatttctgc ttgagattct ttcaatgaat
     2221 tcgtcatttt attgaaatca tctgctaact catcaaattc atctttgtca tgtacgggga
     2281 gctgtacatc aaaattacca ttcgtcactt ctttcgtcgc attccttaac cgattgatac
     2341 gcttaacttg gaatgctgca aaagcatagc tggcaataac tgcaacgata ctggaaaaaa
     2401 taaatccttt gaacaggttc agtgtaattg gacgaacgct gttatcgata tttcgcgcag
     2461 gttgactaac tacaagtgct ccatagaatt catgattcaa attaaatggc acaagtgcgt
     2521 aagaggtcgc ctgtgcttgt cctaaaatat ttttattcga tgtgaatttt tcttgacgtc
     2581 cattcctcag atttttccat tgatcagctg ttaaggtaaa attcagtaaa gctgtattag
     2641 tcggataaat gacacgttcg tttttatcga taaatataaa gttcacattt tgttctgtca
     2701 gtacttgctc tgtcagcagc aatgcatttt gaaacgcctg atcttgacta aactgcggga
     2761 gcgtatcggc ataggtttgc gttgtctttt caactgattc agcatatcca aacagttgct
     2821 ggtaattgtt ttcttcaatc gtttgttttg tcagttgtgt aaaagaaact ccaacgatca
     2881 ataagatcaa cgcgaccatt ccgcaaaaag ctaagagttg ctgatacaaa taacgcatta
     2941 ggcaacacca gaatcatcga atttgtagcc gactccccaa acagtttgga tgacttgtgg
     3001 tccgaccttt tcgatttttt gtcgtaattt cttgatatgg gcgtccactg tccgttcatc
     3061 accaaagtac tgataatccc agactaattc aagcaactgc tcccgagaga atacttgacg
     3121 tggttttttt gctaaagtaa acaatagatc gaactcttta ggcgtcagtc cttcaattgg
     3181 ccggttgtcc agatacgctt ctcgtgtttt cgtattcatc ttgaaatgac tagtctcgat
     3241 atcaaaatga tcatctgaaa ctgctgcttc ttctcttgct tctgccaact cactacggcg
     3301 atgcaaagct ttcattcgag caataagcgt cagaggactg aaaggttttg tgacataatc
     3361 atctgccccc atctctaagc cgatcacctg atcgctttca gaatctctag ctgtcagcat
     3421 gataatcggc acagtacttg aaactttgcg gatctctctt cctactagca taccgtccag
     3481 tgtgggcaaa ttcaggtcta gtgtaatcat atcccaatgt tgtgggtttt ctaaaaaggc
     3541 agcgagccct tcttttccat catacttgaa agttgcttcc caaccttcat ttaagaaaaa
     3601 catctgcatc atttcagaaa cagattgatt atcttcaatc attaaaatat tcattatcgt
     3661 tccctccagt ttccaggtca tatttctgta atttcttttc tgtcataata aaaataggca
     3721 taattggaaa tactagcaga agcatttcaa tcagaaaata attcgtatgc ccagatgtct
     3781 ttaaataata gccgatcaat gccatcagta agcccataag aaaaaaccag tttccgcttg
     3841 tcttttgagc cagccgccaa tgagcgtctg tttttgcggc aagaggcgaa tgatacccat
     3901 aaaaaggcag atttcctttt gagggcagaa tccgaaaaag actgccaatt attaagaata
     3961 agataccaat actgaaaaaa atcattcttt ccctcctaaa ttctcttctt atagtatact
     4021 ctaaattgtt gactgaacca atatgttcag gaattcttca cgaaaggttt gtcttttgtt
     4081 cattctttgt taagataaac ttattccaat aaaaaaggag ttttatttgt gtcaaattat
     4141 cgtgcaatca ctttctttga tcttgatgga acattactag atgcgaaatc aaaaatcaca
     4201 cccgaagtgg caaaagctat gaacgcatta aaagaaaaca atgttctccc cgtcatcgct
     4261 acaggacgta cagaagcaga aatccactct atcatggaag atgcgggcat tacttctgcg
     4321 gtcaccatga atggttcttt cattcgagta gacggcgaag aaatctattc tcaaacattt
     4381 tcttcagaag aatgtcaaaa aatgtatgat catgtacagt tgaacggtca tgaactttct
     4441 tactataacg atcagaaaat ctggtgtacc ggtcatagcc aaacaatgat caatgcttac
     4501 gacttcattc attcagatgt tccggaaatt gatcctttag gctttaaaga aaacacagta
     4561 aatatgttgc tgatcttatc tcaatcaggt gacgaatact atcacgaaca ttttcctgag
     4621 ctaacttttt atcggaatgg tccttactcg atcgatacag tgaagaaagg aatctcaaaa
     4681 ggggcaggtg tcaaacgtct gcaaaaagaa cttcagctgg aaaaagttcc tacttttgga
     4741 tttggcgatg gtccgaatga ttttgccttg ttggaagctt gcgacaacaa aatcgctatg
     4801 gacaacgcct atgacggatt aaaagaactt tctaccttta tcacaaagaa aaatacagaa
     4861 ggcggaattg tccacgcatt gaagtatttt gatctgattt aagatctttt tttgaagcta
     4921 cctcttttct taagaaaatc gcttattttt tcttaagaaa ggggcagtta ttatataaat
     4981 aatgggatat gattcgcttt tttattgaat ttatcccaat atatgctata ctaattttgt
     5041 atgaaaaata cacgtaaccc ttgttagcta acggggacgt tacggattcg acaggcacag
     5101 tcgagcttga attgcgtttc gtaggttacg tctacgtaaa aacgttacag ttaaatataa
     5161 ctgctaaaaa cgaaaacaac tcttacgctt tagctgccta aaaacagtta gcgtagatcc
     5221 tctcggcatc gcccatgtgc tcgagtaagg gtcctaactt tagtgggata cgtttcaact
     5281 ttccgtctgt aagttgaaaa agagaacatc agactagcga tacagaatgc ctgtcactcg
     5341 gcaagctgta aagtgaatcc ttaaatgagt tgactatgaa cgtagatttt taagtggcga
     5401 tgtgtttgga cgcgggttcg actcccgccg tctccatata tgtatggttg agacagataa
     5461 acatgtatga aaaacgttgt taaatcaacg tttttttatt ttggtcaagg agagaaaagt
     5521 agagaaatac aaaatttttt gcattgattt tgcattcaaa aaaacattca aacatttaga
     5581 aatccccaat acgtattcag gaaaatctat tttaaggttt acaaaaagaa cttttgttcg
     5641 tacactcttt ttgaggtgaa cttttatgct gatggaagga aaaacacaat tatggtttaa
     5701 gcatgttcct tcaaataagt ttttttaatt attatttgtc aaattaagcg agacaaaact
     5761 ttccatttac gtaactcaaa aaaacttcta atggtgtttg gtaatttagt gattttctag
     5821 ggatatggtt tcttttggac gcaacggatg agatgaatcc ttgattgact tggtggaagt
     5881 ccatttcttt tggtagtcca tcttttcgga ggagtccgtt tgaatgttca tttaatcccc
     5941 gttgggaagg cgttcctggg tctgcgaaat aaatatcaat atcattcgta ttactaatac
     6001 ttttccaatt agagaattct tttccacaat caaaggtaat tgatttgaaa agatttttga
     6061 gtacggattg aagccattca ttaatcgaat tttcaatatc aactgcctta cggccttctg
     6121 gtttcaag
//
LOCUS       DAYNVV010000101         5907 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.105, whole genome shotgun sequence.
ACCESSION   DAYNVV010000101 DAYNVV010000000
VERSION     DAYNVV010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5907
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.105"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            209..307
                     /locus_tag="ACGXWR_002705"
                     /pseudo
     CDS             209..307
                     /locus_tag="ACGXWR_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(530..760)
                     /locus_tag="ACGXWR_002706"
     CDS             complement(530..760)
                     /locus_tag="ACGXWR_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HFK0804181.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(990..1808)
                     /locus_tag="ACGXWR_002707"
     CDS             complement(990..1808)
                     /locus_tag="ACGXWR_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFK0804182.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            1969..2658
                     /locus_tag="ACGXWR_002708"
     CDS             1969..2658
                     /locus_tag="ACGXWR_002708"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFK0804183.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            2672..4174
                     /locus_tag="ACGXWR_002709"
     CDS             2672..4174
                     /locus_tag="ACGXWR_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFK0804184.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            4187..4663
                     /locus_tag="ACGXWR_002710"
     CDS             4187..4663
                     /locus_tag="ACGXWR_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFK0804185.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(4822..5781)
                     /locus_tag="ACGXWR_002711"
     CDS             complement(4822..5781)
                     /locus_tag="ACGXWR_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HFK0804186.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWMPDVIIGRKERPVS
                     CGMRTLYRLFSKGIFDVDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEDDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRE
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
BASE COUNT         1927 a          893 c         1050 g         2037 t
ORIGIN      
        1 aggggcagcg agtgtcgacc ccttctaggg ggattaaaaa tacacccgtc ctcacgggtg
       61 tatgggttac tgatagactt gattttaact ggtgtcagaa acttatgtcc agaaagggtg
      121 atgaaatttt ggcaatttac ggctattcaa gaattagcac aagcaaccaa gattacaaaa
      181 cacaaattca aacattagaa aatgctggcg cagaaataat cttcctagaa aatcactgga
      241 ttatcgaaca cctttggaag tatttttgag ttacgtaagt attgatgatc tgtctaactt
      301 aatttgacaa ttaagagtat atttacttca gatggtaagg caacaaaata aaatacaata
      361 ggcagatgaa ctaataaata aaatctgtat taaatacaga taaattaata taaaaatcaa
      421 aaggatcata aacttttaac aagtgatgaa atgggtggaa attgattctt atagacagtt
      481 tgtctcataa cattgaagta ttttgcaatt ttagcattga aacacttttt taatcttcaa
      541 cgttgttctt ataaacaaga tgattgggaa tcttttgaat taacactgta tagcttagaa
      601 caccctttat agaaaacatt cgcttagcaa tcttaataat tccttgtgcc cgatgtcgtt
      661 tagattcagt aggttcctgc tcatcgatca tggaaaaaat ttgaaggatc agatccttaa
      721 taaatttatt taagagagga tgatccattg cttcatccat actcgataaa ctagtgataa
      781 tgagctacac gtttttcttt caagttgatc aatagcttcc acgataaaaa tatctttaga
      841 taaaatcaag aaccgtagga actacaggga tatttggtca ataagagcca ccgctattag
      901 taaaaaataa gctatcaagt atgctctcat cccaagaatt gcctacttca atcgttaaaa
      961 accgttaggt ttagctaagt gggggtagtt cactcaatac ttttatcaat aatagagcgc
     1021 aaaacttttt ctcttaattc aactgaatca atattattgt tttgttcata accatgaact
     1081 aatagatcac aaatataaag ttgtgatatt tttccagcta aagatccacc attaagaaat
     1141 tcttcaatgg ctgtttgtaa aactaagtct gcagactttc ctataggtga atgaatatag
     1201 ttagttatag caataatttt tgcgccattt tttttagcta ttttcaatga atcataagta
     1261 tctttcgttt tcccagataa agaaaaaatg attactaaat cattaactgt taataaagaa
     1321 gcgacttggg cttgaaaatg agggtctagt acagcttttg cttgaactcc tacgcgaaga
     1381 aacatatttt ctaaatcaag actagtattt ccactagatc ccactccaaa tatatatatg
     1441 ttttttgatt gagtgatcat tttaatggct tcattcaatt tttcttcgtc taaaagccta
     1501 atagtggaat agagagcttc tgttaaacta ttagcaattt catcatagta ctttacacta
     1561 gtcggatgtt cttttttttg actaaagtct tcctttgcaa tttcaatttt taaatcagaa
     1621 aaaccagaaa aaccaatttt ttgacaaaag cgaataatag tagcatcgcc aacttttgtg
     1681 tttttcttaa tatcactcat cgtactataa ataatagttt tcccagaatt taaaataaaa
     1741 tcagcgactt ttttttcaga cttcgttaaa aatggataat tttctttaat taaatagata
     1801 taactcatac aaactcctct acaatttcaa cttttctcca ttatactcca aaataataaa
     1861 aaaaactcct aaatactcca tttttatctt tacttttatg aaagcggatg ctatattgtt
     1921 tttggagtta ttatccaaaa ataataaaaa attggagcgt ttaggataat ggataaaaag
     1981 aggtttttag atcttatttc aaaaggtttg attgtttcat gtcaagcatt acctggtgaa
     2041 ccattttaca aagaggaaga aagtttaatg ccttattttg ctttggctgc tcaaagggct
     2101 ggagcagttg gtatacgtgc aaattctgtt cgagatatta ttgaaattag aaagtgtgta
     2161 tcattaccaa tgattggaat tattaaaaga gattatccac cagaatctcc attcattact
     2221 gccactatga gagaagtaga tgaattagta gaaaccggtg ttgaggtaat cgctcttgat
     2281 tgcactctta gaaatcgaca tgatggacta tctataaatt cttttattac taaaataaaa
     2341 gaaaaatatc ctcatcagtt atttatggca gatatttcta catttgaaga aggcaaaaat
     2401 gcatataaag caggaataga ttttgtagga actactttaa gtggatatac tgaggaaagt
     2461 aaaaaacaag atgggccaga tatagatttg attaaaaaat tggtagaaga agggatttgt
     2521 gtaattgctg agggaaggat tcatactcca gaacaagcaa aagagataaa aaaaatagga
     2581 gttgcaggta ttgttgtggg tggtgctatt actcgaccac aggaaattgc atcaagattt
     2641 gttaaagcat taagttaggg ggagaaataa aatgtttaaa aaattttcac aattaggacg
     2701 cgctttcatg ttaccaattg ctatattacc agtagccgga ttactattgg gactgggagg
     2761 agcgttaaca aatgagagtg ctataaatgc ttatccattt ttagatcaac cgtggttgca
     2821 tacaatttta agtattatga gttatgctgg aaatgcagtt tttgcaaacc tagcactaat
     2881 ttttgcaatt ggtattgctg taggacttgc aaatggagat aaaggaacag ctggtttagc
     2941 tggtggagta gcttatttag tatatactgc aactattagt gggtttcttg aacttttttc
     3001 agcaaaagat gcaacactag atacaggtgt agtgggatca attgttgttg gtggtactgt
     3061 tgcattttta cacaatcgtt atagaaaaat tgaattacca caattcttag gtttttttgg
     3121 aggatcaaga tttattccga ttgtttctag tttagctgca atcattattg gttctttctt
     3181 ttatttaatt tggccaccaa ttcaaaatgg tttagtagtt gctggtgaac aaattgccca
     3241 aatgggtagt ttaggaactt ttttatatgg ttttttattg cgtttaacag gtgctgttgg
     3301 actacaccac accatttacc ctttgttctg gtatacatct ttaggtggta ccgaaactgt
     3361 agctggatca acaattgctg gagcccaaaa tattttcttt gcccaactag ctgatccaaa
     3421 ccacactggt ctgtttactt atggtactag attttttgca ggaagatttg caacaatgat
     3481 gtttgggtta ccagcagcat gttatgcaat gtatcgtgca attcctaaga aaaatcgtaa
     3541 aaagaatggt gggctttatt ttagcggggc ccttacatca tttttaactg gaattactga
     3601 accagttgaa tatatgtttt tatttgttgc tccttggctt tatgtgattc atgcattctt
     3661 agatggatta tctttttatt ttgctgatat cttaaatatt cgtgtaggga attccttttc
     3721 aggtggtttg atcgactttt tattattcgg tgtacttcaa gggaatgaca aaactaattg
     3781 gttaaaatta attccttttg gtattgcatg ggcatttata tatttctttg tttttacatt
     3841 ctttatcaaa aaatttaagg tagctattcc tggaatggaa gaagaatcag aagttcattc
     3901 tgaaaaagta ataaacaaaa atacatcatt acatgaagag tctcttatca ttattgaagc
     3961 tcttggtgga aaagaaaata ttgagtctgt tgaagcttgt gcaactcgtt tgcgtgttgc
     4021 tgttacgaat ggggagatta ttcaaaaaca aacaataaaa gacactggtg caactgctgt
     4081 cttcgaagtg aagggtggca tccaagctgt ttttggaggg aaagctgact tattaagtca
     4141 agaaatcaat caaatattag gaaaagataa ttaggaggtt tttaatatgt ttgaaatttt
     4201 caaaaagaaa aaacaagaaa ctttttatgc accttgttcc ggaaaaatca tttccatcac
     4261 agaagtaaat gatcctgtct tttcacaaaa attactaggt gatggttttg ccgtcatacc
     4321 tgatggttca aaaatttatg ctccattggc tggtcgagta acaaatatat ttcctactaa
     4381 acatgctatt aatataaaaa gcaactcagg cattgattat ttgattcata ttggaattga
     4441 tacagttgaa ttacaaggag agcctttttc gatttgtgtt caagaaaatg atgaggttac
     4501 tcctgaaacc tcgttggttg atgtggattt tgacaaaata ataaaatctg gtaaagatac
     4561 ttctgttata gttgtttttc cggagaaaaa tcagttcaat gatttaataa tagataatgg
     4621 tcgaattgct catgggaatt catgtggaaa aatcactttt taaaaaagtg tatataaaaa
     4681 gctataaaat aagctaaata ggatatttgt caaatgaagt tggtgaacag aaagaactgt
     4741 tttctttctg ttcatttttt tattttatta gtaatgattc cccatgccaa atcatgatcc
     4801 gtaatttaaa gttatgattt gtcaaattaa gctagaataa aatgcttctt gtacatagct
     4861 caaaaatatt tcgattggtg ttctgtaatt caatgatttt cttggaatat gattacgttg
     4921 attgctgaca ctggaaataa atgtctgatt cacttctcta aaatccattg atttcggcag
     4981 tccattacga cgcagaatcc cgttagaatt ctcgtttaat gggcgttgag aaggtgttcc
     5041 agggtccgca aaatatatat caatatcatg ttggttacta atggctttcc agttagaaaa
     5101 ttcttttcca cagtcaaacg taatagattt aaagaagttt ttagggaagc gagaaaacca
     5161 ttgattaagg gcagtttcaa tatctaatgc cttacggccg ttgggtttaa tcgtgataat
     5221 gactttagat aatctttcaa ctaaagtaat gacggcactt ttatgatgaa tgccaacgat
     5281 cgtatcatct tcaaggtgac caaactcaga attgaaatca ggataattat caggtcgatc
     5341 atggattgag cgctgatact gttgttttcc ccgtttttcc tgatggccat tgggttttct
     5401 tttacctttc atcggtagtg tgtcaacatc aaatattcct ttagaaaata aacgataaag
     5461 tgttctcata ccgcatgaaa caggcctttc ttttcgcccg ataatgacgt caggcatcca
     5521 accaagagtg actttctctt taatgtaatc tacttcatga gcaggtaatt gaatgacttt
     5581 tctaccacat tttttcttat tttctttata ctggtgccaa taatcaagag cagtcttgcc
     5641 ttgcttgaac ttattgacta cattataaat agtttgtata gcacgtccca ttcggttagc
     5701 gatttcaacc ggcttattat gttgaagata atatgattct atcattgtca gttcgtctat
     5761 ggtaagatgt ttgtaggtca tttatggtta cactcctttg ttttctttcg tcggaaatac
     5821 aatttgagtg taccataaat gcctttttat ttttctaact taattttaca attcgcgtat
     5881 cactcttaaa caataagtta aaaaaat
//
LOCUS       DAYNVV010000102         5811 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.106, whole genome shotgun sequence.
ACCESSION   DAYNVV010000102 DAYNVV010000000
VERSION     DAYNVV010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.106"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(1..3607)
                     /locus_tag="ACGXWR_002712"
                     /pseudo
     CDS             complement(1..3607)
                     /locus_tag="ACGXWR_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
     gene            complement(4224..4658)
                     /locus_tag="ACGXWR_002713"
     CDS             complement(4224..4658)
                     /locus_tag="ACGXWR_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804187.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(4675..>5811)
                     /locus_tag="ACGXWR_002714"
     CDS             complement(4675..>5811)
                     /locus_tag="ACGXWR_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HFK0804188.1"
                     /translation="NSEFSIIKEYRSDRTTYFFYDYKKLLTDNIKKTKDFHFFTGDFN
                     EMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNLNVAMADRERLYNSLQNLTLYSLG
                     DIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKTIEQIKIDNLLSQNYDPEIYLFLY
                     ENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDTIRSEKNYSIIVFEKLAQTSITLG
                     MDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIVYYTKEIGKTKIEHLSPLISSVVQ
                     FIGLNIYKRITVKEIANYFSVSETKLRESFKNEMHITIYNYISKRKISTAKIMLKSNH
                     TISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLGLVDNFNNIS"
BASE COUNT         1669 a         1126 c          836 g         2180 t
ORIGIN      
        1 ttggtaggtt ggttacatta tctgttagat ctactgtgcc tccaacttct actttttcgc
       61 cttctactgt tggctcatat ttatcggcgt cagaacgatt gtctgtcact gtaacatcta
      121 cttcaacttc atcagatgat ccatctggat atgtcactac aacagtccct tttttatttc
      181 cagctgcgct aacatctact ttttctttcc aagtatactt agtatctttt ggtaaatctt
      241 ctttgttctt aattccctca aatgcgtctg gttccttatt caattctgta gtcacttttt
      301 gaccttcagg attatatttg tcagcgtcag atttatcatc cagttttgtt gcacttgata
      361 caaattctgt atcatctgct gtaattggtt gagttgcttc ctctggccat ttcgcatctg
      421 tataaccatc ttttgctttc aacactggaa gtttatcttc tggtaagctt acgccgtctt
      481 tcactgcaaa gactgttgtt ccactttcaa tacttgttcc ttctcctgcg gtgaaggtta
      541 ctttgtggta gcctgcagga atgttttctc ctggattttc aatgatatca tccagttttg
      601 ttgcacttga tacaaattct gtatcatctg ctgtaattgg ttgagttgct tcttctagcc
      661 atttcgcatc tgtataacca tcttttgctt tcaacactgg aagtttatct tctggtaagc
      721 ttacgccgtc tttcactgca aagactgttg ttccactttc aatacttgtt ccttctcctg
      781 cagtaaaggt tactttatga tagccagccg gaatgttatc ccctgggttt tcaatgatat
      841 catccaattt tgttgcactt gatacaaatt ctgtatcatc tgctgtaatt ggttgagttg
      901 cttcttctgg ccatttcgca tctgtataac catcttttgc tttcaacact ggaagtttat
      961 cttctggcaa gcttacgccg tctttcactg caaagactgt tgttccactt tcaatacttg
     1021 ttccttctcc tgcggtgaag gttactttgt ggtagcctgc aggaatgttt tctcctggat
     1081 tttcaatgat atcatccagt tttgttgcac ttgatacaaa ttctgtatca tctgctgtaa
     1141 ttggttgagt tgcttcttct ggccatttcg catctgtata accatctttt gctttcaaca
     1201 ctggaagttt atcttctggc aagcttacgc cgtctttcac tgcaaagact gttgttccac
     1261 tttcaatact tgttccttcc cctgcggtga aggttacttt gtggtagcct gcaggaatgt
     1321 tttctcctgg attttcataa atatctttac ttacagttac tgctaaatcg gtcgtgccta
     1381 cagaaccatc ttggtaaaca attttaatag gaattgttcc agtaatcggc tccgattctc
     1441 ctacaccttt agctggagtg aatgtaacaa taccagtgtt tgcatcaaca cttgcattac
     1501 cgaagtcctt attatagaca tctgaaattg aaaaggcatc tttagctaaa ggaacatctg
     1561 gtttatcaaa tgtaggtttt ccactttgaa ctgtcgtttc tggagttgtt gttataggta
     1621 cgtatgttgc atcattttcc atagcttgag aagcttttac agcaaactct acatccacgt
     1681 cgaaagttcg atttccgatc ttaacagtta caataccttt cgtactatca gtaacgttag
     1741 aagtatcagg ctctgttttc catgaatact ctgcatcttc aggtaagttt ttattattcc
     1801 gaattgattc tttagcatct ggtttaaatc caactaccac ggtttgttta tcaaccgctt
     1861 ttggtgattc cttaataacg gttgaacctt cttctggttt atcaaaacct ggagaaacga
     1921 tttggatttt taattcatct ttcgcgatta atttacttga atctacaccc gtaaattcaa
     1981 attctacagt atctgaaatt ggagccccat ctttttcatt tggagcgata gttttttctg
     2041 ctaatacagt accttcttta tcaacaagtt gggctttgtg acctgttccc gctaactcgt
     2101 ggatgaatac tttcccctta actgttgtgt caacatcata tacttcttct aattcaggtt
     2161 tcccgatata tggattcgtg tctccgctct cttctttatc gtcagggttt ccatcaccat
     2221 caatatcttg caaataataa taacctgttc cataagtgtt ctggattaat tttttattcg
     2281 tatccgacaa ccaagaatca aagatgaaat cttcaccaaa tggtttattt tcttcaactt
     2341 gtgctgttgc tttcatatct tctaagattt catctaatgg cttagtcaat tgtaaaacat
     2401 atcgaataac gactggacgt ggacttgcat tagcaaaatc gataagttta gttaaatcat
     2461 tattagttat tgaacctatg ccataatttt catgaccttc ccgtcgctcg attgctaaat
     2521 cagctacttt tgttccggat tcaaacgaaa catcatatgt tactttgtca gcctgaacca
     2581 tgtgcatctg tatacccgct acatatggaa ctaatcgttc atcaattttg taattagcat
     2641 accaaggcgt gccctttgcg gaagatgaat atgagaaatt ataatttttc gttaacttat
     2701 gatctaagat tatagctcca ttagcacctg tggatcctga accatctttt gtttgagtat
     2761 taggtttctc atattttgca cttactgatc catgtttaaa ctggtcagga ttattttcag
     2821 atacatctaa gctattatag aaatcatctg aatctgttaa aaagtagccc gtactatcaa
     2881 tacccggtac aattttatca tcgtcttgat gacttaccaa gtagattcga tacattaaac
     2941 gatcggtctt gagattgtct atgcctatct ctttaaaaat ttcatctagg ctcttttcaa
     3001 acgtaattac cccattagga gcggtttgcg tatcggttgt ttctgcccca gcaaataatc
     3061 catcacttgc acgaatataa ttgaccttcc aaatatttgt aggtctaccc agcgaatcat
     3121 taattcttac aaaggtccgt ctagaagatc caattccttt ctttggatcg acctgaattt
     3181 tttctacata tttagctaat cgttcatcta attgaagacg gatttcccag tttttagttg
     3241 atgctgcaat attatgtttt ccgtaaactt caaatccaat tgtattgcct tttagtgtgt
     3301 ctccagttag ttcttgagga ctaaattgta aatcctaaaa gttataattt ttcgtataac
     3361 caggattctc ctgaaaagta ttccccgaag ctactttgtc acctacttgt acggagctta
     3421 tcgctgtttc aagtgggctg cttggagaaa tttcatcttg tgctttaact agttcagttg
     3481 ttcccaagac aagaccaaca ccaatcaaaa cagatgcaac cccaacactt aattttttga
     3541 tactgtactt caatactcgt ttctttgttt tttctagaaa tactctctta ttattcttgc
     3601 taaccattat tcaaatcaac tcccttaata attactttcc tagtaagaat aaaagataaa
     3661 tctgatacgt attattcaca gaataggaat cttactaacc ttatgttaac taatttactt
     3721 agagaatttc atgaacatta caacaaaaaa agtacatttc ttcatgtttt tttcggatat
     3781 ttgtgctttt taaccattca gcagctgaaa acatataaaa agatatgtat gtattctttc
     3841 tgaaattaag ttcatttcta tgcgatgaag catgttttca aaatattacc ctttcttaga
     3901 ttaaacttca gagtattcaa ataacggaat aaggagcctt atcccgcatt actgaatgag
     3961 actgtgacat aagtaaaaag gtgacttcaa attccttctt cggaatttga aatcaccttc
     4021 tttataatta taaagtatcg gtttcacagc atttctgaat gattcctaga atcttaaacg
     4081 aatgattgga gttatcaaca ttttttcact cgtttttagc gaaacaaaaa atgacatttg
     4141 tcacagcctc attaaattat tgattctttt tctttataat tgaattgtcc atatttaaag
     4201 tgtctagtac tctacatgaa taattaattg ctttcactca aatacttata atctattaac
     4261 ttgtagttgt ttaacttttc tgaaaaagtt agacccacgt aataatcttc ccagctttct
     4321 ctttcaatta actgatccaa tttttgataa tccataaatt catcatgtat caaaaagaat
     4381 aaataacttg atattttagc atctagctta atcagattaa ataatgtttg tttaaaattg
     4441 ctaccattaa tatgactgat agattctcta gcttcttcac ataaactttt tactttatta
     4501 attactactt tgtcatattc atttaacaca ctattattac cattacttag acgctcagat
     4561 tctacgaaac aactcaaatc agaaatttcc caaaaaaatt ttttgttaaa atccaatttc
     4621 ctcaactcct ccaaactacg taaatgatat agtctcataa taaaataaaa cctctcagct
     4681 aatgttgttg aaattgtcca ctaaacctaa ttgatattgc ttaggagata cacctgcgta
     4741 ctttttgaat actctcgaaa agtgtgaaga atctgaaaat cctaaaccta aagaaacttc
     4801 actgatagta tggtttgatt tcaacattat tttagccgta gaaatttttc gcttagagat
     4861 ataattataa atcgtaatat gcatttcatt cttaaagctt tctcttaatt tagtttcact
     4921 tacagaaaaa taattagcta tttcctttac agtaattctt ttatagatat ttaagccgat
     4981 gaattgaacg acagaagaaa ttaagggaga aagatgctct atcttagttt ttccgatttc
     5041 cttagtataa taaacaatcc cagaatccct cacttttaag acctcaggta acgatacagc
     5101 taattcgttt tcttgtatca aagcatctct actttgatac gcttctatta tatccattcc
     5161 taatgttata gacgtttgtg ctaacttttc aaaaacaatg atagaataat ttttttcaga
     5221 ccgaatcgta tctccactaa cacttggaat tattccatta ctcagattaa aaaccatgtt
     5281 ttctaaattt cgaatatctc catttttaac atattccagt attttatttt cataaagaaa
     5341 cagatatatt tctggatcgt aattttgtga taacagatta tctattttga tttgctcgat
     5401 agttttactt agattttctg tatattcaat taacggttca tggaatagat cttctatttt
     5461 tccagtaaaa aaataatgaa ctaaaatcag aatatctcga atgtctccta aagaatacaa
     5521 agtcaaattt tgcaatgaat tatagagtcg ttctctatca gccattgcaa cattcaaatt
     5581 gttcattttt agtttaaaaa aaactttatc aatattattt gctctaaatg gaccaaataa
     5641 gtaatatctg gttttaaaca tgtatagaag aaacatctca ttaaaatcac cagtaaagaa
     5701 atggaaatct ttagtttttt taatattatc agttagtaac tttttataat cataaaaaaa
     5761 ataagtagtt ctatctgagc gatactcttt tataatactg aattcggaat t
//
LOCUS       DAYNVV010000103         5689 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.107, whole genome shotgun sequence.
ACCESSION   DAYNVV010000103 DAYNVV010000000
VERSION     DAYNVV010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.107"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(488..1297)
                     /locus_tag="ACGXWR_002715"
     CDS             complement(488..1297)
                     /locus_tag="ACGXWR_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFK0804189.1"
                     /translation="MVKESVIGKKELRSIFWRSFFMQSSWSFDKMMAYGQMNGIERSL
                     RKIYPNDDDYYTALQRHTETFNITPHIAPFVMSLSVTMEEENAKNPEFDTDAINKIKT
                     GLMGPLSGIGDSFFWGTFRVIAAGIGISFAQQGNILGMILYFTLYTAIHFIFKWLATK
                     YGYVLGTKFIDDTEDNHMIDKLSHGASILGLTVIGAMIGTMVTLNTSLKFTVGGAETS
                     LQSIFDQIFPGLLPLGITFLCVWLYSKGHKTITIILGIFVLCFLGTLGGIF"
     gene            complement(1297..2043)
                     /locus_tag="ACGXWR_002716"
     CDS             complement(1297..2043)
                     /locus_tag="ACGXWR_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFK0804190.1"
                     /translation="MIQAILIALVAFLASIDEYTFGASMMGRPLFTAPFVGLILGDLE
                     SGIIIGATLESMFMGSIMVGSATPPEVYASSVLGTAIAIQSGQGVGTAVALTLPLSIF
                     LQMWRNFAYAMPITYFNNKMDEALVNHDFKKAQKYHYVAQPLIVGVPSAILVFVATYF
                     GVSTINAMIKLIPQVVLDSFDVAAGVLSCVGLALLIKMMANKAMMPYLFLGFVGVMYL
                     KMDVVGVAVVGLCLALLAVQKLTFEEEEDL"
     gene            complement(2061..2528)
                     /locus_tag="ACGXWR_002717"
     CDS             complement(2061..2528)
                     /locus_tag="ACGXWR_002717"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFK0804191.1"
                     /translation="MIKLLRVDERFVHGQVAFAWTNNLGANCIFVASNEIATNNLRKK
                     TLKMAVPTGTKFVVKDMTEAISVLNGEKIKKYQVFLIVGTVEDAYEITQHVPEIKEVN
                     LGNLKKNENRKMITSSVYLNEQELDLVKKMTENGITVQCQAVPTDKKINPLHD"
     gene            complement(2528..2938)
                     /locus_tag="ACGXWR_002718"
     CDS             complement(2528..2938)
                     /locus_tag="ACGXWR_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFK0804192.1"
                     /translation="MRKIVIATHSMMAKGLKDTLEFIIGPQKSLLAITAYIDSDYSIN
                     QEIEQLFSDLAPDDELIVTVDLLGGSVSNAFSEQIGKDNFYLISGVNLPLLLELCLSG
                     EQDTKKLIQKAMNSGNEGIVLVNELLEKTEEDDF"
     gene            complement(2949..3962)
                     /locus_tag="ACGXWR_002719"
     CDS             complement(2949..3962)
                     /locus_tag="ACGXWR_002719"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFK0804193.1"
                     /translation="MLGFSEERFLSVLNGAVKNIETINQVADAISEKGFKNLYLVGSG
                     GTYATISPLAYLLSTHSELDYYHEIAAEVVCSQPKKINKDTVLITSSLTGTTQETVDV
                     VKYANSQGATTIAFVGNAATPLGEIVDYAIENDADNDTLVEELQLQFFALGARLMKNN
                     GEFPEYDEFIQTLQKMPEVLLSVRQQNDQKALEFAEKHKNTEFHMFVGAGNTYGAAYE
                     YAMCVLEEMQWIATKSIHAAEFFHGTIEMTDKSMSFVLLKGEDQTRPLVDRVERFVNK
                     YSDVVTVFDTADFELAGVPSAMRQYVAPMVMATALERVSAHFEKVRDHSLDIRRYYRT
                     VEY"
     gene            4179..4913
                     /locus_tag="ACGXWR_002720"
     CDS             4179..4913
                     /locus_tag="ACGXWR_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFK0804194.1"
                     /translation="MNTEELTNKLIQDIEQEKYKYAQAIPSERDFVQIYEMNRSAVKK
                     AIQQLVNKEYLLKIHGKGTFVKKNIHEHLQIKFHGLSELLEREGIQPSSLILASEIKP
                     AGHIVGKALQLEPTEEVFHLVRLRSGDGEPISIEDTYIPLNLIPDLQAFDFQIFSFYS
                     TLAAYHYQIENIYQTISSSKVSNKEARLLKTSLNRPVISLAITAVTTNEQAVEYTEVV
                     VLPEFAAIYTKNVHQGKEMKIYAQID"
     gene            4897..5607
                     /locus_tag="ACGXWR_002721"
     CDS             4897..5607
                     /locus_tag="ACGXWR_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFK0804195.1"
                     /translation="MPKLINLLAYDLIDKIIAYIHEHHLTPGTKLPSERDLSEMFNVN
                     RTTLRGALQKLVDNGTLRAQTNSGYYLTAPKFEKNAHHFFTPIEDSLLSKQRLQLKAT
                     ALSPKKAAALCPELNDFKQQQPQAYLEYIDAEAISLMLLIPMETLKKSNFSDNPFQDF
                     KSLAYTRSQEISLITDNDVAADLLGVDKEEVLLFVREEIRAGKELAAIALGYTISRRC
                     NIQVNVATTLQSGSVAKF"
BASE COUNT         1832 a         1195 c          943 g         1719 t
ORIGIN      
        1 aagcgacaaa aaccacgagc aggtccattc atcctcaaac ctcggtgatc ttcgcggttt
       61 aacaccatca gaagaaatgc acaaaaataa taaggagagt ctgagacata aataaattcc
      121 cagactttta gtgagtctaa atccgaataa acggtgggtc gaaagcaact ctagctgcgc
      181 gtcgatcgca gcaatctcta ggtgctatgt tcggataaat ggtggtcaaa agtcagattt
      241 tcggccattt cgtaacagcc aaccagacaa aaagcgtctg ttttgtcttc tactccaatt
      301 gctcaaatct tagcgacttt tggcttggtc ttactctaaa cagtttgtaa gcctaaactt
      361 tatttgctgt ttgtttctaa gatcaaagca aaactacttt ttagttggtt acttttacaa
      421 gttcttttta ctgttgaata aatgtaaatc ttaagaacaa atatttactt ctataattcc
      481 aagtttctta aaaaattccg ccaagtgtac ctaaaaagca taaaacaaaa attcctagaa
      541 taattgtgat cgttttatgc cctttggagt aaagccagac gcataaaaag gtaattccta
      601 atggcagcaa gcccggaaaa atttgatcaa aaatactttg taatgaagtt tcagctccac
      661 caaccgtgaa ttttagtgac gtatttaaag taaccatcgt gcctatcatc gcgccaatta
      721 ccgttaaacc taaaatcgaa gcaccatgag ataatttgtc aatcatatgg ttgtcttctg
      781 tatcatcaat aaatttagtt cctaaaacat agccatattt tgtcgccaac catttaaaaa
      841 taaaatgaat ggcagtatac aaagtaaaat aaaggatcat gcctaaaata ttcccttgtt
      901 gagcaaaaga aatacctatg ccagccgcaa taacccgaaa agttccccag aaaaatgaat
      961 cgccaatacc tgataaaggt cccattaatc ctgttttgat tttattaatt gcgtctgtat
     1021 caaattcagg atttttagca ttttcttctt ccatggtgac ggacaagctc ataacaaaag
     1081 gcgcaatatg cggtgtaatg ttaaatgttt ccgtatggcg ctgcaacgct gtataataat
     1141 catcatcgtt cggatatatt ttacgtaagg aacgttcaat accattcatt tgtccatatg
     1201 ccatcatttt atcgaaggac caagaggatt gcataaaaaa ggagcgccaa aatatacttc
     1261 ttaattcttt tttcccaata acactttctt ttaccattat aaatcttcct cctcttcaaa
     1321 agttagcttt tgaacagcca gtaacgctaa gcaaagtccg acgacagcca caccgacaac
     1381 atccattttc agatacatta cgccgacaaa tcctaagaaa agataaggca tcatcgcttt
     1441 attcgccatc attttaatta ataacgctag cccaacacaa gaaagcacac cggccgcaac
     1501 atcaaagctg tccaatacaa cctgaggaat caacttgatc atcgcattga ttgtagacac
     1561 accaaaataa gtagctacaa aaactaaaat ggccgatgga accccaacga ttaaaggttg
     1621 agccacataa tgatattttt gtgctttttt gaaatcatga ttgactaatg cctcatccat
     1681 tttgttgtta aaatacgtaa ttggcattgc ataggcgaag ttacgccaca tctgaagaaa
     1741 gatggacaaa ggtaaagtca acgcaacggc agttcctact ccttgacccg attgaatcgc
     1801 aattgctgta cctaaaacac tggaagcata aacttcaggg ggcgtcgcac tccctaccat
     1861 aattgagccc atgaacatgg attccaaggt ggcaccaata ataattcctg actctaaatc
     1921 tcccaaaatc aaaccgacaa aaggcgctgt aaatagcggt ctacccatca tcgatgcacc
     1981 aaatgtgtat tcatcaatag acgccaaaaa agctaccagt gcgattaata ttgcttgtat
     2041 catattcttc ccctcctctt ttagtcatgc aaaggattga tttttttgtc cgttggtaca
     2101 gcctgacatt gaactgttat cccgttttca gtcatttttt tcaccaagtc cagttcttgt
     2161 tcattcaagt aaacggaact agtaatcatt ttccgattct cgtttttctt taaatttcct
     2221 aaattcactt ctttaatctc aggtacgtgc tgagtaattt cgtaggcatc ctccaccgtc
     2281 ccgacaatta aaaatacttg gtatttcttg attttttctc catttaaaac agagatggcc
     2341 tctgtcatat ccttcaccac aaattttgtc cctgtaggaa cagccatttt tagtgttttt
     2401 ttgcgcagat tattggtagc gatttcatta cttgcaacga aaatacaatt tgcacctaag
     2461 ttatttgtcc aggcaaaagc aacttgccca tgaacaaaac gttcatctac tcgtaataat
     2521 ttaatcatta aaaatcatcc tcttctgttt tctctagcaa ctcgttcacc aaaactatcc
     2581 cttcattccc gctattcata gctttttgga ttagtttttt cgtgtcctgt tcacctgata
     2641 agcaaagctc taaaagcagc ggcagattta caccgctgat taaataaaaa ttgtctttac
     2701 cgatttgttc ggagaaagcg ttagacacgc ttcctcccag taaatctacc gtcacaatta
     2761 attcgtcatc aggcgctaag tcggaaaata gctgctctat ttcctggtta atggagtagt
     2821 cactatctat atacgcagtt attgctaaaa gtgatttttg aggaccaata ataaattcta
     2881 aagtatcctt taagccttta gccatcatgg aatgcgtcgc aattacaatt ttcctcatag
     2941 ctcttacctt aatattccac agtccgataa taacgacgaa tatctagtga atgatcccgc
     3001 accttttcaa aatgagcact cactcgttct aaggccgttg ccataaccat tggcgctaca
     3061 tactgacgca tagcgcttgg tacacctgct aattcgaaat ccgcagtgtc aaaaaccgtc
     3121 acaacatcgc tatatttatt tacaaaacgc tctacgcgat cgactagcgg acgcgtttga
     3181 tcttcacctt ttaataacac aaaactcata gatttatcag tcatttcaat agtcccatgg
     3241 aaaaattcgg ctgcatggat cgacttggtg gcaatccatt gcatttcttc cagtacgcac
     3301 atagcatatt cataggcagc cccataagta ttcccggctc caacaaacat atgaaattcc
     3361 gtatttttat gtttttctgc aaattcaagt gctttctgat cattttgttg ccgaacactt
     3421 agtaatactt ccggcatttt ttgtaatgtt tgaataaatt catcatattc aggaaactca
     3481 ccgttatttt tcatcaggcg tgcacccaaa gcaaaaaact gtaactgaag ttcttctact
     3541 aatgtatcgt tgtcagcatc attttcaatc gcataatcca cgatttcccc gagtggtgta
     3601 gcagcatttc ctacaaacgc aatcgtcgtt gcaccttgac tattggcata cttaacaaca
     3661 tcaacggttt cttgagtcgt accggttaat gaagatgtga ttaacactgt atctttatta
     3721 atctttttcg gctgtgaaca aaccacctct gcggctattt catgataata atcaagctct
     3781 gaatgagtgc ttaacagata agctagcggg ctgattgtgg catatgttcc accagagcct
     3841 accaaataaa gatttttaaa tcccttctca ctgattgcat ctgccacctg attgattgtc
     3901 tcgatatttt ttactgcacc atttaatact gatagaaaac gttcttcgct aaaacctaac
     3961 atagttaaaa acctccaagt caataatttg aaaaatatat ttgcaaatgc cggcacatta
     4021 acaaaccact taaccttttt tatataccac ctgttaacgt ttttaatgta ccacttatag
     4081 aaaacgctgt caatagtttt taaccacttt tatttttatt tgtaccaaaa tccttttttc
     4141 atgtataata aacaaaaata gactctggag tgtaacgtat gaatactgaa gaactaacga
     4201 acaaattaat acaagacatt gaacaagaaa aatataaata cgcgcaagct attccttcag
     4261 aacgtgattt tgttcaaatt tatgaaatga atcgttcagc cgtaaaaaaa gccattcaac
     4321 aattagtaaa taaagagtac ctactaaaaa tacatggcaa aggaactttt gttaaaaaaa
     4381 atatccatga acatttgcaa atcaaatttc atggtttgtc tgaattgttg gaacgggaag
     4441 ggattcagcc tagcagctta attttagctt cagaaataaa accggctgga cacattgtcg
     4501 ggaaagcttt acagctggaa ccaactgaag aagtatttca tttggttcgt ttaagaagcg
     4561 gcgacggtga gccaatttct attgaagaca cttatattcc attaaatctc atacctgatc
     4621 ttcaagcttt tgatttccaa attttttcat tttattccac attggctgct tatcattatc
     4681 aaattgaaaa tatctatcag acaatttcca gctcaaaagt gagcaataaa gaagcccgtt
     4741 tgttaaaaac cagcttaaat cgtccggtaa tcagccttgc tatcactgcg gttacgacaa
     4801 atgaacaagc ggttgaatac actgaagtag tggttttgcc tgaattcgcc gccatctata
     4861 ctaaaaatgt tcatcaagga aaggagatga aaatctatgc ccaaattgat taatctgttg
     4921 gcttatgacc tgattgacaa aattattgct tatattcatg aacatcattt aacccccgga
     4981 acaaaactgc cttcggaacg ggacctatca gaaatgttta atgttaatcg aactacctta
     5041 agaggcgcgt tacaaaaact ggtggacaac ggcaccttac gggcgcaaac caatagcggc
     5101 tattatttaa ctgcgccaaa attcgaaaaa aatgcccatc atttctttac accgatagaa
     5161 gattctctgc ttagtaagca gcggctacag ctaaaggcaa cggctctttc accgaaaaaa
     5221 gcagcagctc tttgtccgga actgaatgat ttcaaacagc agcaaccaca agcttattta
     5281 gaatatattg atgcagaagc aattagcttg atgttattaa tccctatgga aacattaaag
     5341 aaaagtaatt tctcggacaa tcctttccaa gattttaaaa gtttggcata tacgcgttct
     5401 caagaaattt ctttaataac tgacaatgac gttgcggcgg acttgctggg agttgacaaa
     5461 gaagaggttc tgttatttgt acgagaggaa ataagagccg gtaaggagtt ggcggcgatt
     5521 gctttaggtt atactattag tcgccgctgc aacatacagg ttaatgttgc tacgaccttg
     5581 caatccggtt ctgttgcaaa gttttaaatc tactatcaga taaggtagaa taatagaaaa
     5641 agatagcagg aggaatgacg atgagtcatt ttaaaggaaa gcaatttca
//
LOCUS       DAYNVV010000104         5680 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.108, whole genome shotgun sequence.
ACCESSION   DAYNVV010000104 DAYNVV010000000
VERSION     DAYNVV010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.108"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..1287
                     /locus_tag="ACGXWR_002722"
     CDS             <1..1287
                     /locus_tag="ACGXWR_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein"
                     /protein_id="HFK0804196.1"
                     /translation="SLYPVYHGSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFK
                     IEYSEERQRLAYVRLYGGILHLRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEI
                     VILQNEFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDS
                     DPLLQYYVDSTTHEIILSFLGKVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAE
                     YTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQ
                     GLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIY
                     APQEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVC
                     LTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT"
     gene            1385..2758
                     /gene="tet(L)"
                     /locus_tag="ACGXWR_002723"
     CDS             1385..2758
                     /gene="tet(L)"
                     /locus_tag="ACGXWR_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008493 - tetracycline transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015904 - tetracycline transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HFK0804197.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIKKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
     gene            3322..4584
                     /gene="mobV"
                     /locus_tag="ACGXWR_002724"
     CDS             3322..4584
                     /gene="mobV"
                     /locus_tag="ACGXWR_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /protein_id="HFK0804198.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTA
                     ARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERFNENVNDYNELLEEN
                     KSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHD
                     LEPKKNEFELTHNREVKKERSRDQGMSL"
     gene            4829..>5680
                     /locus_tag="ACGXWR_002725"
     CDS             4829..>5680
                     /locus_tag="ACGXWR_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HFK0804199.1"
                     /translation="MCPNSSIYSDEKSRVLVDKTKSGKVRPWREKKIANVDYFELLHI
                     LEFKKAERVKDCAEILEYKQNRETGERKLYRVWFCKSRLCPMCNWRRAMKHGIQSQKV
                     VAEVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQRFRRMMQYKKINKNLVGFMR
                     ATEVTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKV
                     QMIRPKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKNLKRLSDLEEGLHRKRLISYG
                     GLLKEIHK"
BASE COUNT         1955 a          805 c         1165 g         1755 t
ORIGIN      
        1 tccttgtacc ctgtttatca tggaagcgca aaaagcaaca tagggattga gcagcttata
       61 gaagtgataa cgaataaatt ttattcatca acatacagaa agaagtctga actttgcgga
      121 aatgtcttca aaattgaata ttcggaagaa agacaacgtc ttgcatatgt acgcctttat
      181 ggcggaatcc tgcatttgcg ggattcggtt agaatatcgg aaaaggaaaa aataaaaatt
      241 acagaaatgt atacttcaat aaatggtgaa ttatgtaaaa ttgataaggc ttattccggg
      301 gaaattgtta ttttgcaaaa tgagtttttg aagctaaata gtgttcttgg agatacaaag
      361 ctattgccac agagagagag aattgaaaat ccgctccctc tgctgcaaac aactgttgaa
      421 ccgagcaaac ctcaacaaag ggaaatgtta cttgatgcac ttttagaaat ctccgacagt
      481 gacccgcttc tacaatatta tgtggattct acgacacatg aaattatact ttctttctta
      541 gggaaagtac aaatggaagt gattagtgca ctgttgcaag aaaagtatca tgtggagata
      601 gaactaaaag agcctacagt catttatatg gagagaccgt taaaaaatgc agaatatacc
      661 attcacatcg aagtgccgcc aaatcctttc tgggcttcca ttggtttatc tgtatcaccg
      721 cttccgttgg gaagtggaat gcagtatgag agctcggttt ctcttggata cttaaatcaa
      781 tcatttcaaa atgcagttat ggaagggata cgctatggtt gcgaacaagg attatatggt
      841 tggaatgtga cggattgtaa aatctgtttt aagtatggct tatactatag ccctgttagt
      901 accccagcag attttcggat gcttgctcct attgtattgg aacaagtctt aaaaaaagct
      961 ggaacagaat tgttagagcc atatcttagt tttaaaattt atgcgccaca ggaatatctt
     1021 tcacgagcat acaacgatgc tcctaaatat tgtgcgaaca tcgtagacac tcaattgaaa
     1081 aataatgagg tcattcttag tggagaaatc cctgctcggt gtattcaaga atatcgtagt
     1141 gatttaactt tctttacaaa tggacgtagt gtttgtttaa cagagttaaa agggtaccat
     1201 gttactaccg gtgaacctgt ttgccagccc cgtcgtccaa atagtcggat agataaagta
     1261 cgatatatgt tcaataaaat aacttagtgt attttatgtt gttatataaa tatggtttct
     1321 tgttaaataa gatgaaatat tttttaataa agatttgaat taaagtgtaa aggaggaatt
     1381 aattatgaag tgtaatgaat gtaacagggt taaatacaac caaattttaa tttggctttg
     1441 cgttttatct ttttttagcg tattaaatga aatggttttg aacgtctcat tacctgatat
     1501 tgcaaatgat tttaataaac cacctgcgag tacaaactgg gtgaacacag cctttatgtt
     1561 aaccttttcc attggaacag ctgtatatgg aaagctatct gatcaattag gcatcaaaag
     1621 gttactccta tttggaatta taataaattg tttcgggtcg gtaattgggt ttgttggcca
     1681 ttctttcttt tccttactta ttatggctcg ttttattcaa ggggctggtg cagctgcatt
     1741 tccagcactc gtaatggttg tagttgcgcg ctatattcca aaggaaaata ggggtaaagc
     1801 atttggtctt attggatcga tagtagccat gggagaagga gtcggtccag cgattggtgg
     1861 aatgatagcc cattatattc attggtccta tcttctactc attcctatga taacaattat
     1921 cactgttccg tttcttatga aattattaaa gaaagaagta aggataaaag gtcattttga
     1981 tatcaaagga attatactaa tgtctgtagg cattgtattt tttatgttgt ttacaacatc
     2041 atatagcatt tcttttctta tcgttagcgt gctgtcattc ctgatatttg taaaacatat
     2101 caagaaagta acagatcctt ttgttgatcc cggattaggg aaaaatatac cttttatgat
     2161 tggagttctt tgtgggggaa ttatatttgg aacagtagca gggtttgtct ctatggttcc
     2221 ttatatgatg aaagatgttc accagctaag tactgccgaa atcggaagtg taattatttt
     2281 ccctggaaca atgagtgtca ttattttcgg ctacattggt gggatacttg ttgatagaag
     2341 aggtccttta tacgtgttaa acatcggagt tacatttctt tctgttagct ttttaactgc
     2401 ttcctttctt ttagaaacaa catcatggtt catgacaatt ataatcgtat ttgttttagg
     2461 tgggctttcg ttcaccaaaa cagttatatc aacaattgtt tcaagtagct tgaaacagca
     2521 ggaagctggt gctggaatga gtttgcttaa ctttaccagc tttttatcag agggaacagg
     2581 tattgcaatt gtaggtggtt tattatccat acccttactt gatcaaaggt tgttacctat
     2641 ggaagttgat cagtcaactt atctgtatag taatttgtta ttactttttt caggaatcat
     2701 tgtcattagt tggctggtta ccttgaatgt atataaacat tctcaaaggg atttctaaat
     2761 cgttaaggga tcaactttgg gagagagttc aaaattgatc ctttttttat aacaggaatt
     2821 caaatctttt tgttccatta aagggcgcga ttgctgaata aaagatacga gagacctctc
     2881 ttgtatcttt tttattttga gtggttttgt ccgttacact agaaaaccga aagacaataa
     2941 aaattttatt cttgctgagt ctggctttcg gtaagctaga caaaacggac aaaataaaaa
     3001 ttggcaaggg tttaaaggtg gagatttttt gagtgatctt ctcaaaaaat actacctgtc
     3061 ccttgctgat ttttaaacga gcacgagagc aaaacccccc tttgctgagg tggcagaggg
     3121 caggtttttt tgtttctttt ttctcgtaaa aaaaagaaag gtcttaaagg ttttatggtt
     3181 ttggtcggca ctgccgacag cctcgcagag cacacacttt atgaatataa agtataatgt
     3241 gttatacttt acttggaagt ggttgccgga aagagcgaaa atgcctcaca tttgtgccac
     3301 ctaaaaagga gcgatttaca tatgagttat gcagtttgta gaatgcaaaa agtgaaatca
     3361 gctggactaa aaggcatgca atttcataat caaagagagc gaaaaagtag aacgaatgat
     3421 gatattgacc atgagcgaac acgtgaaaat tatgatttga aaaatgataa aaatattgat
     3481 tacaacgaac gtgtcaaaga aattattgaa tcacaaaaaa caggtacaag aaaaacgagg
     3541 aaagatgctg ttcttgtaaa tgagttgcta gtaacatctg accgagattt ttttgagcaa
     3601 ctggatccag gagaacaaaa acgatttttt gaggaaagtt ataaattatt ttccgaacga
     3661 tatggcaagc aaaatattgc ttatgcaaca gttcataatg atgagcaaac ccctcacatg
     3721 catttaggtg ttgtgcctat gcgtgatgga aaactgcaag gaaaaaatgt gtttaatcgt
     3781 caagaactgt tatggctaca agataaattc cccgagcata tgaaaaaaca gggttttgag
     3841 ttgaagcgtg gtgaacgtgg ctctgaccgt aaacatattg agacagctaa atttaaaaaa
     3901 caaactttgg aaaaagagat tgattttcta gaaaaaaatt tagcagttaa aaaagatgaa
     3961 tggactgctt atagcgataa agttaaatca gatttagaag taccagcgaa acgacacatg
     4021 aaaagtgttg aagtgccaac gggtgaaaag tccatgtttg gtttgggaaa agaaataatg
     4081 aaaacagaaa agaaaccaac caaaaatgtt gttatatcgg agcgtgatta taaaaactta
     4141 gtgactgctg cgagagataa cgataggtta aaacagcatg ttagaaatct catgagtact
     4201 gatatggcga gagaatataa aaaattaagt aaagaacatg ggcaagttaa agaaaaatat
     4261 agtggtcttg tagagcgatt taatgaaaat gtaaatgatt ataatgagtt gcttgaagaa
     4321 aacaagtctt taaagtctaa aataagcgat ttaaagcgtg atgtgagttt aatctatgaa
     4381 agcactaagg aattccttaa ggaacgtaca gacggcttaa aagcctttaa aaacgttttt
     4441 aaggggtttg tagacaaggt aaaggataaa acagcacaat tccaagaaaa acacgattta
     4501 gaacctaaaa agaacgaatt tgaactaact cataaccgag aggtaaaaaa agaacgaagt
     4561 cgagatcagg gaatgagttt ataaaataaa aaaagcacct gaaaaggtgt ctttttttga
     4621 tggttttgaa cttgttcttt cttatcttga tatatataga aataacgtca tttttatttt
     4681 agttgctgaa aggtgcgttg aagtgttggt atgtatgtgt tttaaagtat tgaaaaccct
     4741 taaaattggt tgcacagaaa aaccccatct gttaaagtta taagtgacca aacaaataac
     4801 taaatagatg ggggtttctt ttaatattat gtgtcctaat agtagcattt attcagatga
     4861 aaaatcaagg gttttagtgg acaagacaaa aagtggaaaa gtgagaccat ggagagaaaa
     4921 gaaaatcgct aatgttgatt actttgaact tctgcatatt cttgaattta aaaaggctga
     4981 aagagtaaaa gattgtgctg aaatattaga gtataaacaa aatcgtgaaa caggcgaaag
     5041 aaagttgtat cgagtgtggt tttgtaaatc caggctttgt ccaatgtgca actggaggag
     5101 agcaatgaaa catggcattc agtcacaaaa ggttgttgct gaagttatta aacaaaagcc
     5161 aacagttcgt tggttgtttc tcacattaac agttaaaaat gtttatgatg gcgaagaatt
     5221 aaataagagt ttgtcagata tggctcaaag atttcgccga atgatgcaat ataaaaaaat
     5281 taataaaaat cttgttggtt ttatgcgtgc aacggaagtg acaataaata ataaagataa
     5341 ttcttataat cagcacatgc atgtattggt atgtgtggaa ccaacttatt ttaagaatac
     5401 agaaaactac gtgaatcaaa aacaatggat tcaattttgg aaaaaggcaa tgaaattaga
     5461 ctatgatcca aatgtaaaag ttcaaatgat tcgaccgaaa aataaatata aatcggatat
     5521 acaatcggca attgacgaaa ctgcaaaata tcctgtaaag gatacggatt ttatgaccga
     5581 tgatgaagaa aagaatttga aacgtttgtc tgatttggag gaaggtttac accgtaaaag
     5641 gttaatctcc tatggtggtt tgttaaaaga aatacataaa
//
LOCUS       DAYNVV010000105         5560 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.109, whole genome shotgun sequence.
ACCESSION   DAYNVV010000105 DAYNVV010000000
VERSION     DAYNVV010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5560
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.109"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            181..495
                     /locus_tag="ACGXWR_002726"
     CDS             181..495
                     /locus_tag="ACGXWR_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFK0804200.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            516..893
                     /locus_tag="ACGXWR_002727"
     CDS             516..893
                     /locus_tag="ACGXWR_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFK0804201.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            903..1676
                     /locus_tag="ACGXWR_002728"
     CDS             903..1676
                     /locus_tag="ACGXWR_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804202.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            1698..3101
                     /locus_tag="ACGXWR_002729"
     CDS             1698..3101
                     /locus_tag="ACGXWR_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFK0804203.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            3283..4467
                     /gene="mobT"
                     /locus_tag="ACGXWR_002730"
     CDS             3283..4467
                     /gene="mobT"
                     /locus_tag="ACGXWR_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HFK0804204.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            4464..4754
                     /locus_tag="ACGXWR_002731"
     CDS             4464..4754
                     /locus_tag="ACGXWR_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804205.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            4751..4972
                     /locus_tag="ACGXWR_002732"
     CDS             4751..4972
                     /locus_tag="ACGXWR_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804206.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            5014..>5560
                     /locus_tag="ACGXWR_002733"
     CDS             5014..>5560
                     /locus_tag="ACGXWR_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804207.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKL"
BASE COUNT         1880 a          941 c         1101 g         1638 t
ORIGIN      
        1 ttttaaatat agtaggaatc ggacgctcag tacggagcgt ctattttttt acccaatttt
       61 gaaaggaagt gaacttatga aaataaaaaa tcaagaatca aaaggtcgct ctcccccctt
      121 taaaaccatc acacaaataa gattcattca aacataaaaa cagaaaggat aggtaaaaat
      181 atggaactta aatatgtcat tcccaatatg gaaaaaacat ttggacaatt agaatatgct
      241 ggtgaaggga acattgaaca acgtcgaata aatggcagac caaccattct ctctcgtagt
      301 tacaatttat actcaacgat tcaacgagca gatgatattg ttgtcattct tccctccgaa
      361 gctggcgaga aacattttga atccgacgaa aaagtcaaac tcatcaaccc acatattacc
      421 gcagaaggtt ataaaattgg caatcgagga tttaccaatt acattatgca cgcagacgat
      481 atggtgaaag cataagaaag gaaaggtgaa aaaatatgag attagcagaa ggtattgtga
      541 ttgaaaaaga ccagacattt ggcacattga aattttccgc cttgcgtcgt gaggttcgta
      601 tccagaatga agatggtacg gtttccgaag aaattaaaga acgtacctat gacttaaaat
      661 caaaaggaca aggacgcatg atacaagtca gtatccccgc ttctgttcct ttgaaagaat
      721 ttgactacaa cgcagaagtg gaattaatca atcctgtggc agataccgta gcgacggcta
      781 cttttcgagg ggcagacgtt gattggtacg tgaaagcaga cgatcttgta ttaaaaggac
      841 agacaaaacc tcatcagaaa tataaaaaag aagcgtccga aagtgaaaaa taggtgttgc
      901 ttatgacaaa cacaccattg attttgaaag aaattccgaa ggatgaagcc atttctttta
      961 ttcggcaata ccattattca aagatactcc ctagattgtg taaatacttt ctagggattt
     1021 tttcagaaga aaaattatta ggcgttgtgg aattaggctg gggtacgcaa cccctacaaa
     1081 ccatacgcaa actctttccc gacagttccc ttcaaaccac agattattta gaaattggaa
     1141 agatgtgttt tcttccagaa atgaatcaaa ccaattattt tggcagtcaa gctctttcag
     1201 ctctaattaa gtggttgaaa gaacatacgg actgtcattt tttatataca ctggcagatg
     1261 gaattgaggg aaaatgtggc tatgtctatc aagcgtccaa cttcttttac tgcgggtatt
     1321 tcaagacaag tgtctatcgt gataagcagt catgggaaaa gatacaccct cgaagtgctc
     1381 gccttttatt agaggaaaat gctcgctttg aacaggtaga gaaaaagcat tggctttccc
     1441 aggcattttg cgaatacaaa gggattgaga aaatcaatgg acgcatgttt cgctatctct
     1501 atccgttgac aaaagaagcg aaaaaactgt taggacacac tctctatcga cgtcattatt
     1561 atccgaaaga aaaaaattta cgctttgaaa agcgaatcgc ttatcagaaa tatgaagcca
     1621 tttctcaacc aacttttgat aaacaggctc gtatctacaa tacacaatta ttttgatagg
     1681 tggaaaggag gatttttatg ccattgcttc atgacagagg agagcgaatc aaagccaacg
     1741 ataagcactt ggtctatcat tttgtactaa tttcattgct ggtagttttt ctagtcgtcc
     1801 tactcccttt tcattggaga gcgttacaat cggtgaactg gcaagcagtt cagttagata
     1861 catttttcta tcaacttcat acgccatact tttggagcag tattctcact gctctttttg
     1921 tatgcggact tatcagctgg ctttattatc actatcgtat agattctata aaacagttag
     1981 agcaccgtca aaagttagct cgtatgattt tagaaaatca ttggtatgaa gccgaagaaa
     2041 ctcaatcaga gggattcttt aaagatttac ccagcaagaa aaccaaacaa cgaatccgcc
     2101 attttcctaa aatatattat cgaatgaaag atggactaat ccatattcat gtagaaatca
     2161 ccttagggaa atatcaagat cagcttttgc acctagaaaa caaactagaa acaggattgt
     2221 attgtgaatt agtggaaaaa acgttgaaag attcttatgt agagtatgtc ctactttatg
     2281 atactattgg caatcgaatt ggcattgaag acgtggtagc tcaagatgga cgtgtcaaat
     2341 tgatggaatc ggtctattgg gagttcgatt ctctccctca catgttaatt gctgggggca
     2401 ctggtagtgg aaaatcctat tttattctca cattgattga atctctcctg catacaaatg
     2461 caaagcttta tattcttgac cctaaaaatg ctgatttggc agacttaggg gcggtcatga
     2521 ataatgtcta ttaccgtaaa gaagatatgt tggcatgtat caatcaattt tacgaagata
     2581 tgattgatcg cagtgaaacc atgaaacaac accctaacta taaaacagga gaaaattatg
     2641 cttatcttgg tttgtctgcc aattttctta tttttgatga atatgtggca atgatggata
     2701 tgctaggtcg tgaaagtacc accgttattc ataaactcaa acaaattgta atgttaggac
     2761 gacaagcagg cttcttttta attcttgcct gtcaacgtcc agacgcaaaa tattttagtg
     2821 atgggattcg ggacaacttt aacttccgtg tggctttggg tcgtatgtct gaaatgggct
     2881 ttggtatgat gttcggaagc gatacacaaa aacaattttt cttaaaaccc atcaagggaa
     2941 gaggttacgt ggatacagga aaaagtgtga ttagtgagtt ttatacaccc cttgtaccaa
     3001 aaaggtacga tttcttagga gaaataggaa aagtcattca aaaaaagcaa tctgagcctg
     3061 taccgcacga agtgaaaggt acaggttcag acttgctttg attggtgtgg cgttagccac
     3121 gccaatcctt tagccccctc tatctaacag gggggcacaa atacaactga aaacaggcaa
     3181 ttctcatcaa ccaatgttga tggtacaaag gattgcggaa aatatgaaag gtgtaaactc
     3241 aagggtcata gtttacatct tttttagatt ggaggtttgc gaatggaaaa cgaaaaaatt
     3301 tggattaagg aattgaaaga aaagcgactg gcttatggcg tttctcaaaa taaactggcg
     3361 gttgcttctc atattaccag accttaccta tcggatattg aaacaggcaa ggcagtccct
     3421 actcaacagg tgaaagaaga tttactgaac gctttggaac gcttcaatcc cgataaccca
     3481 ttggagatgt tattcgacta tgtacggatt cgattcccta ccaatgatgt ggctcaaatt
     3541 atcggtgagg ttttacgttt gaatatggat tatatgctac acgaagactt tggctattat
     3601 tcttatcccg aacactatcg tttcggtgat attgttgtcc tagtctctca tgatgtaagt
     3661 aaaggtgttt tattagaact gaaaggaaaa ggctgtcggc aatttgaaaa ctttctattg
     3721 gctcaacatc ggagctggta tgatttcttt caagattgca tggaacataa aggtattttc
     3781 aaacgcttgg atttagctat caacgataaa acagggattt tgaatattcc agatttggca
     3841 aagaaatgta aacaggaaga atgcatttcc gtctttcgaa gctttaaaaa ttatcgcagt
     3901 ggtgaattgg ttcaccgtga tgaaaaacca tacatgggaa acacacttta tattggctca
     3961 ttaaaaagtg aagtctattt ctgtatatat gagaaagatt atgagcaata cgtgaaaaat
     4021 gatgttccct tagaagacgc agaagtaaag aatcggtttg aaattcggtt aaaaaatgac
     4081 cgagccaccc aagccatgaa agatttattg gcacatcaac aggcggaaaa aacagccttt
     4141 gaaattatca atcgctatat ccgctttgca gataaagacg acactaaacg tcggagtgat
     4201 tggaaaacta atgaacgttg ggaatggttt atcggtaaaa atcgtggagc attacgccta
     4261 accacacagc cagagcctta ttcttttgaa cgaacattga actggttaca tcatcaagtc
     4321 gcccctacat taaaaatcgc aagcatttta gatgttctca acggtacaac cattatctcc
     4381 accatgattc aggaagccaa actgacagaa aaacatgaga aattaattga acaacaacat
     4441 ctagccatgg aggatttgat tacatgagcc ttttaacaaa agaattaaag aagttagggt
     4501 ttcagtgtgg cattgagttt caagcgtata tacaaaatac agggaaatat acgtctctca
     4561 ttattgaggg aaaacggcaa gctggtgata ccatctatac ctatgatttt tacaaggtga
     4621 gattttataa taattatacc aatcgagtaa ccgtctatgg agagcattta accccttttc
     4681 aattattaag gcgtgtaaaa agctatatct attatcgaga aaaatatctt aaggaaagga
     4741 ggacaatcac atgaattttg ggcagaattt gtacaactgg ttcttggata atgcacagtc
     4801 attggtattg ttagcgattg ttgtcattgg actgttttta ggttttaaac gagaattttc
     4861 aaaactcatt ggcttcttga ttattgctct aatcgccgtc ggacttgtgt tcaatgcagc
     4921 tggcgtgaaa gatgtgttat taaacttatt taaccgaatc attggtgctt aacagatatt
     4981 tttcatgata aaataggaag tatatatttt gttatgaaag gatttatgaa tatgtttaca
     5041 aatgatcaat ttaaatctct tttaattaaa acattagaaa gaaagagctc ttcaaattat
     5101 tatgaaggag gtaacgagat tgtttctaaa atgaaaatat cagaggtaac tttagatgag
     5161 actgacgatt ttacttatta taaaggatat aaaaagggct ggaatacgct ttgcacatat
     5221 cttaaaataa gagttccttt tgatgattta gacttttttg aaagtcataa agatttgatt
     5281 acccagacag caagctccat atatgataaa caaggtgata atgtattagt ggatactatt
     5341 ttagtaccac ttccagagaa ttacgaagta attaacttta gtcagttgaa aattagtgat
     5401 gtggtttcac aagctattga agacgctgag tcttttatga gtaatggtga atatcaacgt
     5461 gcctttgaca gagttcacac tgcttttcat ggatatttaa ttgaaatact aaaaaaatat
     5521 gaaattacag ttcctagaga cgaaaatcta tctaaattat
//
LOCUS       DAYNVV010000106         5339 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.110, whole genome shotgun sequence.
ACCESSION   DAYNVV010000106 DAYNVV010000000
VERSION     DAYNVV010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5339
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.110"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(62..286)
                     /locus_tag="ACGXWR_002734"
                     /pseudo
     CDS             complement(62..286)
                     /locus_tag="ACGXWR_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877485.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(840..926)
                     /locus_tag="ACGXWR_002735"
                     /pseudo
     CDS             complement(840..926)
                     /locus_tag="ACGXWR_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            2092..3132
                     /locus_tag="ACGXWR_002736"
     CDS             2092..3132
                     /locus_tag="ACGXWR_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFK0804208.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            3956..4288
                     /gene="traE"
                     /locus_tag="ACGXWR_002737"
     CDS             3956..4288
                     /gene="traE"
                     /locus_tag="ACGXWR_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HFK0804209.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4907..5248
                     /locus_tag="ACGXWR_002738"
     CDS             4907..5248
                     /locus_tag="ACGXWR_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HFK0804210.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDNEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1943 a          728 c          899 g         1769 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aaccgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccacttgcag atgtagtgtg cagttacctc tgcaaatggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa accccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattata ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt agtacttaaa caatctaaaa aatagttatc ccaattgtta tgcttttata
     1081 atacgattat ttgtaacaaa atgaatatta tataattaaa cactaccata tttaggtagt
     1141 gtttaattat tagcaaaaca aaaaatattt attctattct cttaacttca actaagttat
     1201 gctgcacacc tttatataaa tcatatgcaa ctcattagct agacaaacta caagcatgta
     1261 gttttatctg ttaattatgt actacctaaa taaagtagtt tataattagc aagtatatat
     1321 atttaaaaat ttaagattaa tttttttatg acttgtacaa atttatctga tattctctta
     1381 ttaagaacta cctaatttgg gtagttctta ttttttacat tttaagtagt atttaattgc
     1441 aatttggtag tattttttta ttatcttatt cttagaacgg tagtacttaa tataaatata
     1501 ggtagtatct aatttaagta ttaatggtag tatctaaatt aacaggtagt atgtaactac
     1561 tttaaagtaa tttttttcag attaacacag tagtatctta ttaaataagt taattttaat
     1621 ggtagtacat aattattata tatatctgac attggtagta cttattgtat tttttagtag
     1681 tatataatct attgttttct agcctaaagc cttgtcttat aagaataata taatatatac
     1741 tactgaaata aggtagtata tattactagt aatggtagta tgttttatat gcataaggta
     1801 gttcttaatt tattttttgt tttgacactg gtagtactta attatcttta attttaaaac
     1861 taaattttat tcatacgttt ttctggtagt atttaattat aaataatatt tatttaaagt
     1921 agttcttaat gactttaaag gtagtacata attcatttta tttctgattt taggtagtat
     1981 ttaattaaaa aacagtttta atgcgtttgc attttttatt tatctttgct attttcgaaa
     2041 agagtaggta attttacata aataaaacaa cgtgaaagta gaggatctac aatgactgat
     2101 tttaaatttt ttaaggcgga tagagtttac aacgaattat tttatcaatt tccaaaagtc
     2161 tttattgttt ctgacgaata caaaaaaatg aaagattcaa ctaagattgc ctatatgctt
     2221 ttaaaagcaa gattagagat cgcaatcagc aaacggcaaa tcgatgaaga aggtaatgtt
     2281 tattttactt atacgacaaa tgaactatgt agagtattaa actgccaaaa acaaaaagcg
     2341 atagcaatca aaaaagagtt ggaatccttt ggtttattat tacaaaagca gatgggattt
     2401 aacaaacagt tagggaaaaa taatcctaat agactatatc tagcagaatt aaaagtctca
     2461 gaaaatgata tctacttact cgaaaaattt gatagagaga atagggaaaa cgttgataaa
     2521 tcagagggta tgaaaatcat acccaccctc gacgaaaaat cagacgctga atcccttggg
     2581 gctcaagagg gtatgaaaat cataccgtgc caaaacgttg ataaatcaga gggtatgaaa
     2641 atcataccag aacttaataa taatatatta gacactaata gacacaatat agacactgaa
     2701 aaagaccgcc tacaagatca attgttgtta gacaattttg agacaattat gacaaacgac
     2761 agcattgcta cgtttgtccc tgaacgagta ttaaatttga taaaaacatt ttcttcaagt
     2821 tacagtgaag ctcaaaaaac cgtccagact attcataatg caaagaaaaa agctgaaata
     2881 gaaagtgata tttcgatagt ttttgaagaa ctcgatagtt attatgtcaa tgcagaacaa
     2941 gaattataca cgacactgtt aaaagcctat caaaaattaa aaaccgaaaa agtcgaaaat
     3001 atccagaacc tgatttttgt ctatgtaaaa aattggttta tcgaaaaacc aatagctgct
     3061 aaagtatcaa gtgaaaaacg tttgaattat gcaagctccc caagcactat tacgaaagac
     3121 tggttagagt gaaactttac tgacaaagtg attgttgctt catggagtaa cattaaaatt
     3181 aaaaattttt tattattcta attatattac gaatattaca aaataatagc tattttaata
     3241 gaatttataa gttaaaatat tatgataaaa atcacaaacg tagcctttta cgtcataagt
     3301 gttaaaagaa ataattaatt tcaaatatag aaaagggaac gtatgtttgc atactccttt
     3361 tttttgagtt ataataatac gcgaagagag ataatttcat tatttaaaca agctaaaaat
     3421 cttgatatta cttcttttca ggcaatacga atattattcg cttacatttt ttgtataaat
     3481 ttaattgtct gctatgcttg tgatgaattg attttcgttt tgcacttttg gatgataaat
     3541 ttggacaatt gaaaatacaa aaaaaagaaa ggcggtatga actcggaagg ctggtaacct
     3601 tcgtcagcgt tcatacacgg cattaagatt tggcccttaa tgcgttaacc tttcagtgtt
     3661 acggtattac ccgcaatgga tttagtataa cagatattca aaagtgatac cacttttttt
     3721 ggctgtgtta aggttaaaaa tacgtgatat tacgatgaat ctatgcctaa gcataatgtt
     3781 ataaaaatgt ccgtgtggct ctttgccgta tgacgaacgc tgaaattaga gggaacgcat
     3841 gtttggatgc gttccctctt ttttgtttgt catgaacgaa aatcaattct ctatttttga
     3901 aaaataacaa gaaaaacttg ttaaaaatat ttaaagaaat tgggtggttt attttatgtc
     3961 atatacagga attttgagtc tcaaagatat ttgtcactac ggtaaacggt gtaccgctac
     4021 agagaaaatc acgaagaaac tatcaactgg ccaaagtaaa accgttgtgc agtgtaagaa
     4081 atatataatc cagaaagaca aagtctcaga ggaaatgatt tattacattg ggaaacaaaa
     4141 gcaaataatt ttaaaagatc ctatcccctt aaaagagcta tatccaacaa tcaaacatgt
     4201 ttatgaccaa aacggtgtac tgattggtcg aagaaaaaat ggagtcttgc gttgtaccgc
     4261 aaaagggatg gggcgtttga tcggctgaat tgatcattct cataacttgt attttatcgt
     4321 ttttcgcttg cttgaaaata ttgtcgagac ttctaaagga acttagagtc actagaaaaa
     4381 taaggagtag acttgatcta tcaacaattc ccttcgggga gtgacggggt aggttttaac
     4441 gattggtaac gtaaaaaatt ggtcaatcga gtaaatgcgc ttgtttggat agtggtgaaa
     4501 tgaatttgtg taaataataa gcgcagagta aacaagaggg aatttagaag ttagacaagt
     4561 tagaatagcg tctagattaa tcatgagcag ctactaaggg atctagactt tgacgcaaac
     4621 tcatggaata aggagtaggt cttctcgtaa tggggaggac gcacaagaaa ttgtgtcgtg
     4681 tgctgcagta catgtagata cttgcgagga cgttgattat tggatcaatc gagcatttac
     4741 cgctgtctac tagggtttct cgtttcggac gccataaacg agtcgaaatt ttttatgtat
     4801 ttttaagtaa acgaaaaacg ataaaatatg aacaagtcct gaataaagtg aaaaaattaa
     4861 tataaagcat agagaaaatg aaatttacgt aatggaggaa tgacaaatga aaaattatga
     4921 tccgaatata cgattgggca cacatactat taaggtttct ttccaacgtt gggattacaa
     4981 aggatttgtg acgtttagaa ggggcggaaa ttgtaaagga ttagatgttt tagcattaga
     5041 cgaggatgat ttatacgatc aaacattgac tgataatcca attggattcg gcttgctacc
     5101 tgaagataat gaaggtaatg aatggtttaa aatgacgctt atgaatgata atggagacga
     5161 attatctgtt gaagatactt ggtcatattt gagtgattat attgtcagct ttgaaatcat
     5221 tgaatttgta gcggataaag aagaataaaa actggaggaa taaattttac agataaaggc
     5281 ttagaaggag tcacgacgat taataaaaag gtagtattac cttaggcatt gagtaagga
//
LOCUS       DAYNVV010000107         5198 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.111, whole genome shotgun sequence.
ACCESSION   DAYNVV010000107 DAYNVV010000000
VERSION     DAYNVV010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5198
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.111"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            24..695
                     /locus_tag="ACGXWR_002739"
     CDS             24..695
                     /locus_tag="ACGXWR_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFK0804211.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            754..1194
                     /locus_tag="ACGXWR_002740"
     CDS             754..1194
                     /locus_tag="ACGXWR_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804212.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1206..1874
                     /locus_tag="ACGXWR_002741"
     CDS             1206..1874
                     /locus_tag="ACGXWR_002741"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFK0804213.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1938..2561
                     /locus_tag="ACGXWR_002742"
     CDS             1938..2561
                     /locus_tag="ACGXWR_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HFK0804214.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2617..3003
                     /locus_tag="ACGXWR_002743"
     CDS             2617..3003
                     /locus_tag="ACGXWR_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HFK0804215.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3216..4607
                     /locus_tag="ACGXWR_002744"
     CDS             3216..4607
                     /locus_tag="ACGXWR_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HFK0804216.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
BASE COUNT         1727 a          861 c         1095 g         1515 t
ORIGIN      
        1 atgatgaaaa aagggggaga aaaatgaatt ttttagttgt tttaaaagat actctgattg
       61 agcgatctac atttctatat gttcaattgc aggaaaataa aacattgctg catttttcac
      121 cagagttcca tctagagggg ctaacattag gagaaatcta tcaagcagaa gggctgtcgg
      181 ctgttttgca cttttttaag gtagaattgg aattaccagt aaaagattat atcgagcttt
      241 ctcttgaatc ttgggatcga gcagtggttg aactgtttcc agaaggttta atgatcgata
      301 caaacgatgg gaagatccat ctgactgcag cagaactgca aaaacaaatg cgttatcaaa
      361 tagatgacga aaattctttt tctattttta gacgtcagca aaagattcta aaaagctttt
      421 taaaagtgat cagtaaaaaa cggaatctga tcaaaacgac acagctgttg aaaaaatatc
      481 caggtctgct tcacacgtct attcaatttc ctcaattgat tacgatgatc catcgtttta
      541 tacgtatgca acagctacca tctaagaagc tgtttcttcc attgacggac acatttcgag
      601 tagtcaacag agaagataaa aagaaagtga ttgtgattga ctttaccaga aatcggaatg
      661 tccttcacca agttgcaatg gaaaaggcca attaaggctt tttctttttg gatttttttg
      721 tcataataaa tattagatga tggaggagat aatatgatgc aaacatggtt agaaaggcta
      781 atacgatttc agcagaacta tcacaaactt atgcagggaa gatatgcgaa atttgatcag
      841 ttgaatcgcg gtctattgat cgctgcgctt gtctttagtt tgctaagtcg ttggttgccc
      901 tatagaatcg gacaattgtt gttcatcgtc tttttcggat ggatgatatt tcgtttccta
      961 tcaaaaaaaa tctaccccag actaaatgag aatcaacgtt atttgaaata tcttgataga
     1021 gtcaaagaaa aatatcatca gataaaaaac aaaaagcaag tcaaaatgga tcgaaaaagt
     1081 tatacttttt ttgagtgccc gaattgtcat caaaagcagc gtgcacctaa aggaaaagga
     1141 cgaatacgtg tgacatgcaa aacatgtggt ataaaattcg aaacgaatgt ttaagggaga
     1201 aaagaatgaa attagtatta ttacgtcatg gcgaaagcga agcaaatttt gaaaattact
     1261 ggacaggatg gctagatgtc gccttaacag aaaaaggaaa agaacaagca gcagttgccg
     1321 gtcaaaaaat gcttgaagcc ggacttcaat tcgatgccgt ttatacctct gttttgaaac
     1381 gtgcgattct taccggacaa gtcgcactag aagaaatggg tcagttatgg cttcctataa
     1441 taaaaacatg gcgtctaaat gaacggcatt atggggatct tgtgggtaaa aacaaagata
     1501 agatgaaaga aatatacgga aaagatcaag taaaaacatg gcgcagagga tatacggaag
     1561 ttccgccgtt aaccgcagaa aatagatttg accgcagata tgatcacttg gatccgcatt
     1621 tgatcccata cggagaaagt ctggaaatga cagtgaatcg gatcattccc ttatggcaag
     1681 atcatctagc accaaaacta aaagatcggc aagatttact agttgtgggt catggtaata
     1741 gcatccgagc actgacaaaa tatttagaag atgttcctga agatcaaatg gatacgatcg
     1801 atatcccaaa tgcacaacca atccagtata cattagcaga tgatttgaca attctggaca
     1861 aaaaaatact ttaaagaaca cctttatcta aaagtgagag atagaaaaaa gaagcaaagg
     1921 aatggaacaa aaggaacatg aaaaattata tatgggactt tgatggtaca ttgtttgata
     1981 cgtatcccgc aatggtagat ggtgcatggc aagcactaaa agattttggt atcagtatgg
     2041 acaaaaaaga aatctacttc aaaatgaaaa agtattctac tagttatttg atcaatgaat
     2101 caaacttgaa tgccagagag tttaatgaat tatttcaccg atatgaaaaa gaaagtacgg
     2161 aagtttcccg tccatttcca gaaacgaaac aagtactgga aatgctaaaa gacaacggcg
     2221 gtcgtcattt catcctgacc caccgtttga cagaatcaac atggggcctg ttaaaagaac
     2281 atcgattggc acatctgatt gaggaagtag tagggatcga tcaggacttt cctcgtaaac
     2341 ctgatccagc atctttaaat tatttgatcg atacttttca tttagaaaga acagacacga
     2401 tgatgatcgg cgatcgtcgt ttagatatcg aagcagggaa aaatgcagga gtcgctactt
     2461 gtctttacga catcgatcat tttctgggtg agatcccggc agattatgtg gtaggaaatc
     2521 tgaatgaaat ccttaccttg cagagcatca ttaaaaagta gtatcccctt tcaaaggaga
     2581 tatgttataa ttttcataaa ggagtgataa aattatatgg aaatcagaag acaaaaagaa
     2641 gttgtagaag catttcatta tgatatgaga ttgccgaacc aagaagtaga aacagatttg
     2701 aaagtaggct tctcgccttt aaaagaaacg atcgaaaact atccgaaaga acatagcatc
     2761 gtaggagcac gcttagagtt ccgtttagtg tttgatacat atgttttatc tggaagtgtg
     2821 agtcagatca atcatatcct caatcggaaa attgaaggtc aaaatgatgt cacacaagaa
     2881 gaagtggacg agctagtagc accgttattc gatatcgtac gccgaatgtc ttatgaggtg
     2941 acagagatcg ccttagatca gcctggggta aaattgaatt ttcaatcaga aaaacaagaa
     3001 tagacagtaa aaacatacct gcgatagatt aaagctatca caggtatgtt tttttattac
     3061 taattgtaag caaaaagaat gtcatttcga taaaaatcgt ctaaaatata aaagtcactg
     3121 aaaaaaattt tttcaggagg atggttgaag aatcattctc gggaaccttt acttccttcg
     3181 atggacttgt cattaataat atgaggagga gaaaaatgac aacactcatc acagttttag
     3241 tggttctagt ttttgcggca ttattatatg tgttctatcg tatgcaaaag cgccatacaa
     3301 aattttcaac acgcgtcttt acagcattag gagttggtat cgtctttggc ggtctgcttc
     3361 aattgatctt tggtgtagac gacaaagtcg ttactcaatc aatggaatgg atcgggattg
     3421 taggtcaagg atatgtatca ttcttgcaaa tgctagttat gcctttagtg tttatttcga
     3481 tcattggtgc attcacaaaa atgaaagttt ctgaaaagct agggaaaatt agtgcgactg
     3541 tattgacttc tttacttgga acaacagcta ttgcagcatt gatcggaatt ggttcaacaa
     3601 tgctgttcgg actccaagga gctaaattca cacaaggagc tgcagaaaca gcacgaatct
     3661 ctgaactggc aacacgtcag gaaacagttg aaaacttatc gattccacag cagattttat
     3721 cctttatccc taaaaacgtt tttgctgatt tagcaggtag tcgtgcaaca agtacgattg
     3781 gagtcgttat tttcgcggca tttgtcggaa tcgcttatct aggcgtgaaa agaaaagcgc
     3841 caaaagaagc agcattcttt tcagatttag tcgacagtct gtataaaatc attatgcgga
     3901 tcgtgacgct tgttttgcgt ttgacacctt atggagtatt tgctttgatg acaaacgttt
     3961 tggcaacaag tgattttgca gctatcgtca atttaggtaa atttgtcgtt gcttcttacg
     4021 tagcattgct tgctgttttg attgtccact cactgatttt gattggtgca aaagtcaatc
     4081 caatcaacta tttcaaaaaa gcctttccgg tattgagctt tgcgtttact tcacgttcaa
     4141 gtgctggagc tttgccattg aatatcgaga ctcagacaaa agctttagga gtagatgatg
     4201 caacagctaa tttctcagca agttttggtt tgtctattgg acaaaacggc tgtgctggcg
     4261 tttatccagc tatgttggca acgatcgtcg caccagcagc tggagtgaat gtctttagtt
     4321 tggaatttat tttgatgctt gtggcaattg taacaatcag ttcttttggt gtagctggag
     4381 tcggtggggg cgcaacattt gcttcactga tcgttttagg ggcaatgaac ttgccagtag
     4441 caatcgttgg gttagttatc tctgttgaac cattaatcga tatggcacgt acagcagtaa
     4501 acgtcagcgg tagcatggta gctggtatcg tgacaagtgc acgcatcaaa gatttagatc
     4561 gcgatgtcat caatgatgat tctaaagtga tcgatgtgaa tgcatagtca aaaagaggtt
     4621 gtgatagaag tggtcagctt taagaaataa gaagaagttt cctaaaaata gtttctcaaa
     4681 tttttgtgaa atttcggctt atttccgaga agctacttct gaaacaccgt gaataagagg
     4741 ttgtgaaaaa gctgccctgc atcaagtaat aagaacagcc aaacaaaaat agttcctcat
     4801 attttacgtt tggttgagct tattaccgca gatgcaagct tttgaacacc gtttaagaaa
     4861 gaggtcgtga gcctgccgtt tcactctgag tcacaaagag caatttcaaa aaatagcttc
     4921 tcatgtttgt tgaatattgt gtcttgtgac cgaggagttg tcaggagaac accgtttacc
     4981 agaggttgtg acttgttttt agtcacgacc tcttttttta tttattccat ataaatacac
     5041 attatttatt ccgaaaagtg aaagcgcaaa taacaaaaac aaccaactta tttattatta
     5101 aagaaaagcg tatttaagta ggacgattct gttgagagct ttcgtagatt ttcccatttt
     5161 cctatggtaa actgacaaag ttgagaatgt tagaacag
//
LOCUS       DAYNVV010000108         5192 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.112, whole genome shotgun sequence.
ACCESSION   DAYNVV010000108 DAYNVV010000000
VERSION     DAYNVV010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5192
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.112"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            137..748
                     /locus_tag="ACGXWR_002745"
     CDS             137..748
                     /locus_tag="ACGXWR_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFK0804217.1"
                     /translation="MYFILPTLYSLLCVMAPCIIYMVFFCKKNTLKHNILILIFMLYC
                     WKVFELTGTGGLTDIFYRPDTGRKFSLVQGSVNLVPFSGLNISFILNIVMCVPLGFLL
                     PIIWKSYRKIVPVFLAGALFSLIIEVSQIITTRATDIDDLIANTFGAVIGFILWAVLS
                     RVVSLKDKSSTVDYLEPYIYILIGFTGKFLLYFPFWFAFEVLS"
     gene            821..1750
                     /locus_tag="ACGXWR_002746"
     CDS             821..1750
                     /locus_tag="ACGXWR_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HFK0804218.1"
                     /translation="MKRFLKWGLVLLASLIVILMCTAVVISYVNRPYARAVYDRIKRI
                     LDKDFYDHLYLGSSFEIINLDTMDIHSYMKKDQEELPASLSKLFTIDYALSVLSLDEQ
                     ITISPTALDMQKADSSTAHLQEGDILSVYDIICAMVLPSGNDAAYSLAIYTGGKLDPD
                     AKNDEERYQSFMKNLDRYLSEQGYKHTHFTDAAGYDSNATTSAEDLTKVAAKLLKNDK
                     FAEIVAKETYRAKSIKGNVYNWNTTNQFMQQDNRYFTEGVKGVKTGSFDGRYNLCVYY
                     TSSSDNHYLLVSFGSESDSRRYVDVQNLLHNLP"
     gene            1887..2645
                     /locus_tag="ACGXWR_002747"
                     /pseudo
     CDS             1887..2645
                     /locus_tag="ACGXWR_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033645.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
     gene            complement(2693..3895)
                     /locus_tag="ACGXWR_002748"
     CDS             complement(2693..3895)
                     /locus_tag="ACGXWR_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFK0804219.1"
                     /translation="MHRKEDFHMNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKT
                     ELTAFLDYEKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYR
                     RTNDTLEKTVIHLFRKGITMSEIADLIEKMYGHHYTPQTMSNMTKSFTEEVTSFKERE
                     LHDRYAAIYMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEI
                     LIDLQERGVKNVLLFITDGLKGMAGAVQRFYPKARFQHCCVHVSRNISHKVRVDDRKE
                     VCDDFKMVYQASSKKAALEARGAFAEKWKTSYPKMVESILSNDYLLTFYDFPLAIRKT
                     IYSTNLIESFNKQIKKYSHRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTD
                     TLASMFTE"
     gene            3975..4499
                     /locus_tag="ACGXWR_002749"
                     /pseudo
     CDS             3975..4499
                     /locus_tag="ACGXWR_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(4706..>5192)
                     /locus_tag="ACGXWR_002750"
     CDS             complement(4706..>5192)
                     /locus_tag="ACGXWR_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFK0804220.1"
                     /translation="LKEAIDQIKTAVLYPHNGLPILLMGVSGSGKTFLAEKIYEYAKE
                     QQVIESNAPFIAYNCAQYFNFSINKIVENLTILDAMKVLRLVQKAVKELEKLMGIEFS
                     NNQLFLLYMHCCSMIERILRKESVDEQADIKEYIQKEGHNYEISKYPAYKTKFESTVI
                     K"
BASE COUNT         1642 a          878 c         1003 g         1669 t
ORIGIN      
        1 cctctaggaa aaaattaact agcaccacgg gttatgatat aataaaatgt attataggca
       61 tttttttaca agaaatagaa gcttgaagtt tatatgaagt tataaaattt aatttatatt
      121 ggaaggagga aaataaatgt attttatact acctacactt tatagccttt tatgtgtaat
      181 ggcaccatgt attatttata tggtattttt ttgcaaaaaa aataccctga aacacaatat
      241 cctgattttg atttttatgc tgtactgttg gaaagttttt gaattgactg gtacaggtgg
      301 actaacagat attttttata gacctgatac aggtaggaaa ttttctctag tacagggcag
      361 tgttaatctt gtaccattca gtggactaaa cattagcttt atattaaata tagtaatgtg
      421 tgtgccctta ggattcttac taccaatcat atggaaaagt tataggaaaa tagttcctgt
      481 tttcttggct ggggctctat tttcactaat tattgaagtc tcacaaatta taactacaag
      541 agcaacagat attgatgatt taatagcaaa tacctttggt gcggttatag gctttatact
      601 gtgggctgtt ttaagtagag tggtgtcctt gaaggacaag tcatctacag tagattattt
      661 agaaccttat atttatatat tgattggttt taccggaaaa ttcttactgt attttccttt
      721 ctggtttgct tttgaagtat tatcctgata attccataga aaataatgag tttgagttga
      781 gaaagaatat tcttgtacac aactctggaa aggaggaagt atgaaaagat tcttaaaatg
      841 ggggcttgtt cttttagcgt ctttgattgt gattctaatg tgtacagcgg ttgttatttc
      901 ttatgtgaat cggccgtatg caagagctgt ttatgatagg attaaacgca ttcttgacaa
      961 agatttttat gaccatctat atctaggttc ttcatttgaa ataataaacc ttgatacaat
     1021 ggatattcat agctatatga aaaaagacca agaagaatta cccgcctcat tgagcaaatt
     1081 atttacgatt gattatgcgc ttagtgtcct aagtttagat gaacagatta caattagtcc
     1141 tactgcactt gacatgcaga aagctgactc atctactgca catcttcaag aaggagatat
     1201 tttatctgtt tatgacatta tctgtgctat ggtcttaccc tcaggaaatg atgcagctta
     1261 tagtttggca atttatacag gtggaaaact tgatcctgat gcaaagaatg atgaagaacg
     1321 ctatcaaagc ttcatgaaaa acttagatcg ttatctaagt gagcaaggct ataaacatac
     1381 tcattttact gacgctgctg gctatgactc caatgctaca acatcagcgg aagatttgac
     1441 aaaagtagct gcaaagctac taaagaatga taaatttgca gaaatagttg ccaaggaaac
     1501 ttatagagca aaatcaatta agggaaatgt ttataactgg aatactacga atcaatttat
     1561 gcaacaagat aatagatact ttactgaagg tgtaaaaggt gtaaaaactg gatcgtttga
     1621 tgggagatac aatctatgtg tgtattatac atctagttct gataaccact atttacttgt
     1681 aagttttggt tcagagagtg atagtaggcg ttatgtagat gttcaaaatc tattgcataa
     1741 tctgccttga aatttcgtgc ctttaagcgc gtatctaaag tttctttgaa aagtttgaga
     1801 atgaagaaag tgagcagtcg aaaaacggtt gctcactttt ttgccctaaa atcgaaaaaa
     1861 tataaaaaag tcctttacaa cacgtctcag gaaaaactgc taagtcaatt ctaatatctt
     1921 gtggagcaag acttgcacct tttgatataa gagagcttag agaactaatg agcgaagatg
     1981 aactagaact cgataaaatt ggagatagaa aaactgcctt gtttgtaata atatcagata
     2041 cagatgatac atttaatttt gtagtttcaa taatgtattc tcaattattt aatctactat
     2101 gtgataaggc agatgatgtg tatggtggaa gacttccagt tcatgttagg tgtctacttg
     2161 atgagtttgc aaatatcggt ttgattccta aatttgaaaa actaatagcg acaattcgtt
     2221 caagagaaat atcggcaagt ataatactgc aagcacaatc tcaattaaaa gcaatttata
     2281 aagaccatgc agatacaata gttggtaact gtgactctac actttttcta ggaggaaaag
     2341 aaaaaacaac agtaaaagaa ttatcagaaa ccttaggaaa agaaaccata gacctatata
     2401 acacatcaga aacaagatca aatcaaaaat cttttggtct aaattatcaa aagactggca
     2461 aggaacttat gagtcaagat gaaataactg taatggatgg tggtaagtgt atttaccagc
     2521 taagaggagc aagacctttt ctatctgata aatttgatat tacaaagcat aagaattaca
     2581 aattgttgga agattatgat aagaaaaact tgtttgatgt agaagagtat ttaaaacaaa
     2641 gatagcgtaa aatattttgt gtaaataact cgtccttctg caaaataatg ggttactcag
     2701 taaacattga agctaatgta tccgtcactt gttggaagcc tttatggctt ctatttaaga
     2761 atttttgatt gtatgtatca aagatggata ctaggaaacg ctctagtgat tcttcatttt
     2821 gaaactgctc ttttctgtgg ctgtatttct tgatttgctt attaaaggat tcaatcaagt
     2881 tcgtagagta aatagtcttg cgtatggcta atggaaaatc atagaaagtg agcaggtaat
     2941 cgttcgaaag gatcgattcc accatttttg gataactggt tttccatttt tccgcaaaag
     3001 caccacgtgc ttccaatgcc gcctttttag atgacgcttg atacaccatt ttaaaatcat
     3061 cacagacttc cttacgatca tcgacacgca ctttgtgact gatattacgg gaaacgtgca
     3121 cacagcaatg ttgaaaacgg gctttggggt agaaccgctg cacggcccct gccatcccct
     3181 ttaagccatc cgtgatgaaa aggaggacgt ttttcacgcc acgttcctgg aggtctatta
     3241 aaatctcttc ccaaatcgtg atagattcag ttggtgcaat cgcatagctc aacacttcct
     3301 ttgaaccgtc cgggcgaatg ccaactgcga tatgaatggc ttccttggcg acggttttcc
     3361 gctttaaagg gatataggtt gcgtccatat aaatagcggc ataacggtca tgaagctcac
     3421 gttccttaaa tgaagtgact tcttccgtaa atgatttagt catattggac atggtttggg
     3481 gcgtgtagtg atgcccatac attttctcaa tcaagtctgc gatttccgac atggtaatac
     3541 cttttcggaa gaggtgaatg acggtcttct ctaaggtatc attcgtccgt ctataagcag
     3601 gaacagtctg ttgcttgaac tcgccgttgc ggtcgcgcgg aatctggaga tgaagttccc
     3661 cgtactcggt cttgaccgta cggtcatagg agccgttacg agaattaccc gtgttaaaac
     3721 caatgcgatc gtacttttcg taatcgagga aagccgttaa ctccgttttg agaagcgtat
     3781 tgacagcttt ttccaaatgg acacggaata attcattcaa atcgccttta ttcgctagag
     3841 tctttagaat ttctgtagta aaatcgttca tatggaagtc ctcttttctg tgaatgtgtt
     3901 gtggtaactc tattctactg aagggacttc cttttttcta tttacacaaa atattttaca
     3961 ctctcggatt gaaagaacgc ggtctttcag gagtaaagat ggtcatctcg gatgcgcata
     4021 tagggctcac aaaagctgtg aaagaatacc ttctttgtgc gagctagcag agatgccaag
     4081 cacatctcct tcgcaacatt tccgacaaat tctccaagaa aatctcaagc gatatcaaag
     4141 aagactttaa agccatcttc aaaacggcaa gcatcgagct ggctggagaa cgtaaacaac
     4201 ttattatgga taaatatggg gaagacaaga aagtcgcaac tgcctgtaaa atattggatg
     4261 agggcttcga agatgccatg caagtaatgg ttttaccaga aaatatccgt caacgattga
     4321 gaacaacgaa tgttcttgaa agactaaatg aagaagtacg ccgtcgtgaa cgtgttgtcc
     4381 gaattttccc aaattgtgat tctgttattc gtatcatcgg tgctttattg atggaaaagg
     4441 atgacgaatg gacttctgca cctagaaaat atcttgaatt tgatcgtaac gagatttagc
     4501 acattaagcc gccaatagta taatatactg gtgagaagta tcaagagacg cttcgctttt
     4561 tgctcttgac acttcttacc agcatattgg accgtagcta ggctcaacaa ggcaaaacat
     4621 cgtactttga gatttccttt ttacacaaga ttttggactt gacacagccc ctatggttct
     4681 taccttgttt atgcttattt aaatcttact ttattacagt actttcaaac ttcgttttgt
     4741 aagccgggta ttttgatatt tcataattat gtccctcttt ttgaatatat tctttgatat
     4801 ctgcttgttc atctacactt tctttgcgta aaatacgttc gatcattgag cagcagtgca
     4861 tgtaaagcaa gaacaattga ttgtttgaaa attcgatccc cattagtttt tcgagttctt
     4921 tgacggcctt ttgtaccaat ctcaaaacct tcattgcatc aaggatcgtt aaattttcta
     4981 cgatcttgtt aatcgagaaa ttaaagtatt gagcacaatt ataggcgata aatggagcat
     5041 ttgattctat cacctgttgt tccttggcgt attcataaat tttttctgcc aaaaaggttt
     5101 ttcctgaacc gcttacaccc atcaataaaa tcggtaatcc gttatgagga tacaagacag
     5161 ccgtcttgat ttgatcgatc gcttccttta aa
//
LOCUS       DAYNVV010000109         5018 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.113, whole genome shotgun sequence.
ACCESSION   DAYNVV010000109 DAYNVV010000000
VERSION     DAYNVV010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5018
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.113"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..189
                     /locus_tag="ACGXWR_002751"
     CDS             <1..189
                     /locus_tag="ACGXWR_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804221.1"
                     /translation="VPYTQERIQTTIDLQVKKLHQELLDQRNKEQKKVLIQRSLDFLA
                     PLCCLVLTLFAFWLVWGG"
     gene            191..880
                     /locus_tag="ACGXWR_002752"
     CDS             191..880
                     /locus_tag="ACGXWR_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804222.1"
                     /translation="MAFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFFL
                     GCIFSLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQALAQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYVKDTKI
                     EEACSDLFGDTNPWFASEEEKKEKQQSVTYERYEILLQQATNMQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1001..1087)
                     /locus_tag="ACGXWR_002753"
     CDS             complement(1001..1087)
                     /locus_tag="ACGXWR_002753"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFK0804223.1"
                     /translation="MFELFICPLLVGVCVSLFSYWLNNRNKK"
     gene            1732..2469
                     /locus_tag="ACGXWR_002754"
     CDS             1732..2469
                     /locus_tag="ACGXWR_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015060391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFK0804224.1"
                     /translation="MSNDIVRYNNGLNSVPLRKFTPIDMDLFWGICSKMKRKGTKEEI
                     FTFKQIKELIDYNINARGDRFANDLIKMSKKIITLSFIYEDEKTYEQLNLFQKFKIDK
                     VNETLLIKVSEEFEYILNSIGTNFTRFELENMTNLKSSYVKELYRQLMAHKDRRSKKG
                     HWFVKIEDFRALLAIPESYRMRDIDKQIFAQAKKEFLNVNSTHPAIFKTFEIKKIKAY
                     KGNKIGSLQIYFEENIPSITLDNWLEK"
     gene            2497..3036
                     /locus_tag="ACGXWR_002755"
     CDS             2497..3036
                     /locus_tag="ACGXWR_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFK0804225.1"
                     /translation="MQPKETFTIKELSELFEISRQAISKHVDKLDPSLLAKNERGYKV
                     VLRSGVLQLASNLGNQRLLYRLHEYEQENDKNVYISSKNVIVNELLDKLREENEFLRE
                     QLSLKEQNNSNMQKLLDQQQQLTLQANQQIEKLQEQLQLAYTEETPEDESTTILSEET
                     ESIEKHTKKKKQKWWQLWK"
     gene            3052..3222
                     /locus_tag="ACGXWR_002756"
     CDS             3052..3222
                     /locus_tag="ACGXWR_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804226.1"
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNS
                     PNEELFVKETDK"
     gene            3671..3895
                     /locus_tag="ACGXWR_002757"
     CDS             3671..3895
                     /locus_tag="ACGXWR_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFK0804227.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            3915..4202
                     /locus_tag="ACGXWR_002758"
     CDS             3915..4202
                     /locus_tag="ACGXWR_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFK0804228.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            4643..>5018
                     /locus_tag="ACGXWR_002759"
     CDS             4643..>5018
                     /locus_tag="ACGXWR_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HFK0804229.1"
                     /translation="MSEQNQNLASDHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVAPG
                     DAQRLSENLKIMQKELQKIWQQL"
BASE COUNT         1882 a          747 c          944 g         1445 t
ORIGIN      
        1 gttccttata cgcaagaaag gatacaaact acgattgatt tacaagttaa aaaactccat
       61 caagagctat tagaccagcg aaataaggaa cagaaaaagg tgcttattca acgatcattg
      121 gattttcttg cccccttatg ttgcttagtc ctgacactgt tcgcattttg gttagtatgg
      181 ggaggctaaa atggcatttt atttacccta tctactcatt tttgttagta tttcaggaag
      241 tatttggctc atctataaaa tttttcaaac aagatattca ttaaaaggct ctaaaattcg
      301 atttaagcga tttttctttc ttggctgtat attttccttg ataatcgttt caagcggctt
      361 attcggcgtt ttagagggaa ataagcgcgt ttctagaagt attttattag gaaatgtcac
      421 tcaaaagtat gaatcagcgc gtgataaaaa gaaaaaagag caagcattag cacaaaaaat
      481 ggaagagttt accacttgtt atgaggaaat gaacgatatt tttgtgaatc aagaaaaacg
      541 tttgacggat aaaaacatgg aaaaactcac tcgtctttat caaaacttgc cagaaaaaca
      601 gcaaaaagag gttcaagaca actatgagcg aaccaaaaaa gacgtgcaat atgtaaaaga
      661 tacaaagata gaagaagcct gtagtgatct atttggagac acaaaccctt ggtttgccag
      721 tgaagaagaa aaaaaagaaa aacaacaatc tgtcacatat gaacgctatg aaatcttact
      781 tcaacaagca actaacatgc aaaatccgac aaaaaaagaa accgccttaa actatctaaa
      841 aagtgtcaag gaatggttag atcagcaaca acaaaattga atttgattta aaatcatgtt
      901 aaactgaatg tgcaaatgat caaacattag atacacgaaa gccccagaga ggtcggattc
      961 tctggggctt tttttcaggt tgatgtcgcc tttattgatt ttacttcttg tttcggttat
     1021 tcaaccaata actgaataaa gagacacaaa ctcctacaag aagggggcaa atgaacagtt
     1081 caaacattag atacacctcc ttccagtcgc aagactgtcg gataggcgac aagttattat
     1141 atcttaaaaa attaaatttg tgtggtgttt ttaagtatca cttgttttag ggttgttagg
     1201 gcttgccctg accgcctgta aggcgcttct cgactagatt aagggaaatt aatcaagaat
     1261 tgtcttagaa cggcttagac aagctttcag agtctcacac ctcctctttg aacaacggtt
     1321 ttagcaaagg agccggaggc gactgcgcag tataatatga gagcatagcg atcacacctt
     1381 tttagcgacc gtagggagca agttttccag tttagaaaaa ttcgcgaacc tttttggagg
     1441 aaaaagtagg agttttttag gcgggaaatt caatgtgctc ttaagatata ctgttagata
     1501 tactgttaga tatactgtta ataataactg ttagggatta gcaaccttat gggagagtaa
     1561 gtattgacat aggtagtggg ggataaattg tcacactatg ggggataaat tgtcacacta
     1621 tgggggataa attgtcacac tatgggggat aaattgtcac actatggggg ataaattgtg
     1681 ttttacatcc tcttatgtct atgataacat aatttattga ggtgattttt attgagtaac
     1741 gatatagttc gatataataa tggattaaat tctgtccctt taagaaaatt tacccctata
     1801 gatatggatt tattttgggg aatatgttct aaaatgaaaa gaaaaggtac aaaagaagaa
     1861 atttttacat ttaaacaaat aaaagaatta attgattaca atataaatgc acgtggcgac
     1921 cgttttgcta atgatttaat aaaaatgtca aaaaaaatca ttactttgtc ttttatttat
     1981 gaagacgaaa aaacatatga acaattaaat ctgtttcaaa aatttaaaat cgataaagtg
     2041 aatgaaacat tattaataaa ggtttctgaa gaatttgaat atatacttaa ttcaatcgga
     2101 actaatttta ctcgtttcga attagaaaat atgacaaact taaagagtag ctacgttaaa
     2161 gagttatatc gccaacttat ggctcataaa gacagaagat ctaaaaaagg tcactggttt
     2221 gtaaaaatag aagattttag agctctatta gcaataccag aaagttatcg catgagagat
     2281 attgataaac aaatttttgc ccaagcgaaa aaagaatttt taaacgttaa ttcaactcac
     2341 cctgctattt ttaaaacttt tgaaatcaaa aaaattaaag cctacaaagg aaataagata
     2401 ggatctctgc aaatttattt tgaagaaaat ataccttcaa ttaccttaga taattggtta
     2461 gagaaataat acctaacaat ttaggaggca attatcatgc aacccaaaga aacctttaca
     2521 ataaaggaat tatctgaatt atttgaaata agtaggcaag caatctctaa acatgttgat
     2581 aaattagacc cgtccttatt agctaaaaat gagcgtggtt ataaggttgt attacgttct
     2641 ggagtattgc aacttgctag caacttaggt aaccaaaggt tactatatag gttgcatgag
     2701 tatgaacaag aaaacgataa aaacgtttat atatcaagca aaaacgtgat tgtaaacgag
     2761 ttgctagata agttgcgtga agaaaatgaa tttttacgag aacaactttc cctcaaagag
     2821 caaaataatt ctaatatgca aaaattactc gaccagcaac aacagctcac cctacaggca
     2881 aatcaacaga tcgaaaaact gcaagaacag ttacaattag cttatacgga agaaactcca
     2941 gaagatgaat caactactat tctttctgaa gaaacagaat cgatagaaaa acacacaaaa
     3001 aagaagaagc aaaaatggtg gcaactttgg aaataactgg agggaacatt catgacaaga
     3061 aaaaatcttc tattcggttc tattttacta ggaattctag gcttcagtcc gatgttattg
     3121 tcagtaatca ataaagggaa taaacatggt gaattgaaat tgaatccaaa ttattacaac
     3181 agtcctaacg aagaattgtt tgtaaaagag acggataaat aataaaaaag actgctcttc
     3241 cgagcagcca gttaaaaaat aatgagtgtt tattcttgaa aaagcacgcg cttatgaagc
     3301 gctaccaaaa atttaccata ttttacaaaa aataacaagt cttaaaaaaa tgacagataa
     3361 aaatgcacaa agaattagat atagataacc gcgaaaaatc aagctttaga aagttgcttt
     3421 tagctagacc aattaaaaat cacaaagtga gcgtctctat ccattggtag aggggctact
     3481 tggcatagtg tacattatgt ctactagctg tttaaataac tgatcttata attttattta
     3541 aacgattatg aattcaaaac tactttttat gacgttaatc attgttatat aataaaatgt
     3601 tatataataa aattactaag attatttaat ataacaagca attttaaaaa aacgaaaagg
     3661 aaaaacaatc atgaaaaaga aagtattaaa acattgtgtt attctaggaa tattaggaac
     3721 ttgtctagct ggcatcggta caggaataaa agttgatgca gctacttact atggaaatgg
     3781 tctttattgt aacaaagaaa aatgttgggt agattggaat caagctaaag gagaaattgg
     3841 aaaaattatt gttaatggtt gggttaatca tggtccatgg gcacctagaa ggtagtggta
     3901 gggaggttat tataatggat tttactaaag aagaaaaact tttaaatgca attagtaaag
     3961 tatacaatga agcaactata gatgactatc ctgacttaaa agaaaagctc tttctttatt
     4021 ctaaagaaat cagtgaggga aaaagtgttg gtgaagttag tatgaaatta agtagttttc
     4081 ttggaagata tattttaaaa cataaatttg gattacctaa atctttaata gaattacaag
     4141 aaattgttag taaggaatct caagtatata gaggatgggc ttctattggt atttggagtt
     4201 aattctttgg aataaaatga aaatgggact gaagaatcaa ttctgattca tcagtcccat
     4261 aaattataga gccgaaaaat tatcatattt atagatttat taatagtaaa tggcataaga
     4321 atctttgaac aacgaaaaaa atgtagctct acctaattat tgatttgcaa caatttcacc
     4381 gaaggtgaaa caagcgaaac tttacaaaaa gtggctagca tttgctagtc ttttttgtat
     4441 tgtggagagt gggggggagg gggattcaag ggggagcttg cgcccctttg acaagcggtt
     4501 atttgcacca aatacgtagg tatttggcta gcaaatatag agcttgccaa acccttttag
     4561 tgagctttac tcattgtacc tttttaggta caatggtatt gcgaacgata cgtccgtagg
     4621 acgtactgaa agggtgggac ttatgagcga acaaaatcaa aatttggcta gcgatcattc
     4681 taaaaaatat acctatcgat ccgagccaaa acaaatcagt tttcgagtga gcgaatctga
     4741 atttgcaaag ctgaagcagt cagctgaagc tttgcaaatg agtgtgccgg ctttcgtaaa
     4801 agccaaggca caaaacgcgc gtctggtgac accgaaagtg gcgccagaca ttgcccaggc
     4861 aatcgcgcgc gatttagcca aagctggagg gaatatcaat caaattgcta agtggtgtaa
     4921 tacacaccaa cacgacgttg ctcctggaga cgcccaacgc ttatccgaaa acctaaaaat
     4981 catgcaaaag gagctacaaa agatatggca acagttaa
//
LOCUS       DAYNVV010000110         4932 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.114, whole genome shotgun sequence.
ACCESSION   DAYNVV010000110 DAYNVV010000000
VERSION     DAYNVV010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4932
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.114"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            85..972
                     /locus_tag="ACGXWR_002760"
     CDS             85..972
                     /locus_tag="ACGXWR_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFK0804230.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="ACGXWR_002761"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="ACGXWR_002761"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HFK0804231.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="ACGXWR_002762"
     CDS             2274..2720
                     /locus_tag="ACGXWR_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFK0804232.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="ACGXWR_002763"
     CDS             2993..4345
                     /locus_tag="ACGXWR_002763"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HFK0804233.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="ACGXWR_002764"
     CDS             4516..4803
                     /locus_tag="ACGXWR_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFK0804234.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1695 a          813 c         1030 g         1394 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt tt
//
LOCUS       DAYNVV010000111         4681 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.115, whole genome shotgun sequence.
ACCESSION   DAYNVV010000111 DAYNVV010000000
VERSION     DAYNVV010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4681
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.115"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            59..913
                     /locus_tag="ACGXWR_002765"
     CDS             59..913
                     /locus_tag="ACGXWR_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFK0804235.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1010..3259
                     /locus_tag="ACGXWR_002766"
     CDS             1010..3259
                     /locus_tag="ACGXWR_002766"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFK0804236.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     NWVITQEEK"
     gene            3262..4437
                     /locus_tag="ACGXWR_002767"
     CDS             3262..4437
                     /locus_tag="ACGXWR_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFK0804237.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTRVTRGAS"
     gene            complement(4440..>4681)
                     /locus_tag="ACGXWR_002768"
     CDS             complement(4440..>4681)
                     /locus_tag="ACGXWR_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFK0804238.1"
                     /translation="PPRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKLGCQNFNSRSV
                     KGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         1634 a          674 c          850 g         1523 t
ORIGIN      
        1 gtaataatat aaacataata aaacaaaaat tatccaaatc taacatagga gggtggatat
       61 ggaaaattct atatatttag taacagaacc taacactcag ctgaaagatt gttactttaa
      121 tttttgtggg tattcaaaaa cagaacctag acatagtttt ggaccagcta ttcgagaaca
      181 atacttaata cacatagtgc tagaaggtga aggctattat tcaattaatg atcaaaaata
      241 ttttctgaag aaaggccaag gatttgttat cccaccagga gtatctactt tttatcaagc
      301 agatgaaaaa aatccgtggt catatgtatg gttgggttta agtggcaatc ttgtagaata
      361 ctatctaaaa gaaattggtg ttggaaagaa tcatcttacc tttaaagtcg aaaatttaaa
      421 ttcatttaaa ggattaattt ttgaaacttt atcgtatgat caggacaatc tagtcagtga
      481 attgtccaga caaaaacaag tttataaatt tttagaactc ctcttaaatt cagctagtta
      541 tctgaacgaa gggataatta ctaaaaagat gaatcctttt gttcgtcaaa caattgaaat
      601 aatacgtgag aatgcgtatc aaaaattatc tgttaaagat attgctgtca gtctatcgat
      661 acacgaaaat tatttatcac gattgtttaa gaatgatatg ggaatatcaa taaaagagta
      721 tattagtgaa atcaaaattt ctattgcaaa cgatctgtta tcatcaactg aatattcaat
      781 ccagcaaatc agtgacaaga taggattctc aacagtacaa tctttttcta aagcctttaa
      841 gaaagcaaat ggtgtttcac cgggagtata tcgaaaacgt agattaggtc taggaatcat
      901 taatggtgaa taaactaaac atttgatttt gataaatatt cgttacttta aacgcttact
      961 atttatgtga gcgtttttta taatgcaata aagaaacgga ggagagctta tgtataagga
     1021 taatgaaatg aatattattt atcgatcaga aaaccaacaa tttcatttgt ttaatcagga
     1081 gataagttac atttttaaga tatcggaaga tggtaaatta ttgcatttat attatggtga
     1141 gaacttacca gataatgact atagtcatct aattgagatg catcatcggc ctatgacaac
     1201 ctatagaaat gaaaacgatt tgctatattc gttagagcac ttaaaacaag aatttcctga
     1261 atatggtaca acagatttta gacatcctgc tatttcatta ctacagaaaa atggctctcg
     1321 cttatcagat tttgtctatc aagggtacga agtggaagaa ggaaaaccta aactagaagg
     1381 tttacctgct acctatgttg ataataatga tgaaagcaaa acattgaaag tttatatttt
     1441 agattcagtt acaaatgttc aagtagaatt attatataca atttatagag attatcctgt
     1501 tattactcgt agcgcgcgag ttatgaataa aggaaaagat attcaaataa tcgagaatat
     1561 tagcagttta tcattggatt tacccgatgc aaattatgaa tggcaacaat tatctggtgc
     1621 ttggggtaga gaaagaacta ttaagtcgcg tactttacaa caaggaattc aatcaatcga
     1681 atctactcga ggtatttcaa gccatcagca taacccattt gttactttaa aaagaaaaaa
     1741 tactgatgaa aatcaaggag aagctattgg tgcagcacta gtttactcag gaaacttctt
     1801 aattcaagca gaagtagata catgggatgt tactagacta caagttggca tcaatccatt
     1861 tggatttaat tggaaactca atccaggaga aatatttaca gcaccagaag cgattctggt
     1921 ttattcaagt aagggtttaa atgccatgag tcaaactttt catcaactat ttagaaaacg
     1981 cttagctcgt ggtaagtggc gagaaaaaga ccgtcctgtc ttaattaata attgggaagc
     2041 aacatatttt gattttgacg aagaaaagtt ggtaaatatt gctaaaaaag catttgatgt
     2101 tggtattgaa ttatttgtat tagatgatgg ctggtttgga gaaagagaaa acgattgtgc
     2161 aggattagga gattggcatg taaatcctaa aagactacct agaggaatcg gcagcctttc
     2221 agaaaaaatt cgtagttttg gtatgaaatt tggtttatgg tttgaacctg aaatggtgaa
     2281 taaggatagt gagttatatc gcacacatcc gaattggatt atttctacac ctaatcgaaa
     2341 acctaatcat ggtaggaacc aatatgtatt aaattttggg ttagatgagg ttgttgaaaa
     2401 tattttcgat caaatgtgta aaatcattga tgaatcaaac ttagattaca ttaagtggga
     2461 tatgaatcgt ccattgactg atgtatttga cagtcacttg tcagcagatc aacaaggaga
     2521 agtattccac agatatgtac taggcgtata tcgcttatat gaaaaactta taacaaaata
     2581 tcctaacata ctatttgagt cttgttcatc aggtggtggg cgctttgatc ctggaatgct
     2641 tcactatgca cctcaagctt gggctagtga tgattcagat gcaattgaaa ggttaaaaat
     2701 tcaatatgga actagtatgc tgtatcctct ttcgtctatt ggtgctcatg tatcaattgt
     2761 tccaaatcat caaacaaacc gtataacacc tataaaaact agaggaaatg tagctttttt
     2821 tggtgcattt ggatatgagc ttgacttaaa tgaattaagt gaaggcgatt tgaggattgt
     2881 aaaagaacaa attgcctttt ataaaaaata tagaaccata attcataatg gtacttttta
     2941 tagactatta tcaccattcg atgatgataa tcaaaccgcg tggatggttg ttagtcatga
     3001 taagaaaacg gctattgttg ctcattataa aacattaaat gaggtaaatg ctccttaccg
     3061 ccgactgaaa ttaaaagggt tagataatga cggactttat aatgtaggac aaaatagttt
     3121 gcgatctgga atggaattga tgagagcagg actagtctgt tcagatgcat ctagtggaca
     3181 aataaatgat cagaatcgac gcccagaaac atttgatttt gattccaaga attgggttat
     3241 aacacaggag gaaaagtaga gatgaataac caaaaaagct tacttcaaaa aggagcaatc
     3301 ttaagtattt cactaatgtt aacaagctct caagcaatta atggtgttat tccacaaatg
     3361 aaacagtctt tggggatatc acaaagtcaa agtgaacttt taggaactgc accaagtata
     3421 actgttattt tgtttatctt attatctagt tactttgcca aaagaatagg aatgaaaaag
     3481 acaataattt taggtttatt attagctggt ataggaggaa ttattccagt atttacagct
     3541 accttccaaa ccgttcttat tagtcgagta atattaggtg ccggtttagg agtatataat
     3601 tcattggctg tgacatatat cagctcttta tactctggca atactagagc aacgctatta
     3661 ggtattagaa attcaatgga agctttaggt cagacaatcc ttatttttct tgctggagtt
     3721 ttagtgaaca ttaattggac ggcttcgttt ttagtctatg caattgcgtt tcctgtagct
     3781 ctcttattcg cgctaaaagt tcctgaaatt agagatgaaa atagtgacat acctgaaaat
     3841 catgtaaaag aaaagatgaa tccaatggtt tttgccctag ttctatttgc aatcttactc
     3901 gtaatgaata gtattgctat ttctgtacga tttgcatcaa ttgcaactga aattaaaggg
     3961 gtaaacttta atgctagtaa ctatttagct ctaatgccta tcttaggaat actagcagga
     4021 tttatgtttg gaccaataaa taagtggata ggaaaaggaa ccctatactt gggaattata
     4081 ttctttataa tttcaaattt gttaattgct gtgtcaaacg gtaatatgac gttcctgcta
     4141 acgggtttat ttttatcaag tataacagga tcatggtgct tcccatttat ctttagtaac
     4201 ttagataaag tcactacaaa gaatacaatt aattttgcta cttcattgat ttttattggc
     4261 tgtaatattg gtaattttat agctcctatt gctatgcaat tagcacaatt tctaacaaga
     4321 agtacaaatt tgactgctcc attttttgta ttcgcaggaa tatttattgt gatcctattt
     4381 gtaacatttt ttgcgacaaa taaaaaaaat actagagtaa cccgtggtgc tagttaattt
     4441 taatatccta aagaatatct caaagttcct tcaaaacgtc gttgtgctcg acttaataga
     4501 acactgtaag ccagtaatat gctttcaaat ctactctcta gccctttaac agaacgtgag
     4561 ttgaaatttt gacaacctaa tttttctaag gaagaaaaaa cagtctcaac tgtttttctt
     4621 tgttttccaa gtaagctgtg gtctagtttt tctgatttat ccatgttttt acgtggcgga
     4681 a
//
LOCUS       DAYNVV010000112         4656 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.116, whole genome shotgun sequence.
ACCESSION   DAYNVV010000112 DAYNVV010000000
VERSION     DAYNVV010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.116"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..402)
                     /locus_tag="ACGXWR_002769"
     CDS             complement(<1..402)
                     /locus_tag="ACGXWR_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFK0804239.1"
                     /translation="MKAVHFGAGNIGRGLIGQILHQNGFDLCFIDTNPELIHQLNQDK
                     GYTIEIIDEMNRSDFIDHVVALNSLSELEEVITATKNADILTTSVGAINLVKIAPIIA
                     QALSKRFEQKHSINIVANENVINASDVLKKEI"
     gene            complement(410..967)
                     /gene="hxlB"
                     /locus_tag="ACGXWR_002770"
     CDS             complement(410..967)
                     /gene="hxlB"
                     /locus_tag="ACGXWR_002770"
                     /EC_number="5.3.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0043800 - hexulose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="HFK0804240.1"
                     /translation="MSYKAAKQNIVREITETLDRISSKDVEQLIKKIEKAERVFFVGV
                     GRVLLALEGMAKRLGHLGIQTVVVGQITEPAITDKDLLIVGSGSGESAFPLTIAKKAK
                     EFGSQVAHIGSNPDSTMKEYSDLFIRIPVQTKLALPEEISSIQPMTSLFEQSVLLLGD
                     SIALVMIEEKAIDMSKLWQYHANLE"
     gene            complement(1007..1711)
                     /locus_tag="ACGXWR_002771"
     CDS             complement(1007..1711)
                     /locus_tag="ACGXWR_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFK0804241.1"
                     /translation="MEKKIILSPSLMCGDLANLEGSIQELESIGMDSLHIDVIDGSFS
                     PSMPLGIETIKRIREITSMNFDVHIMAKDNDNEFFIGEMLKIGVESITFHYETSLHID
                     RYIQLIKNSGTKVGIALNPATPLNVLQYILPEIDRICLMLINPGFATNKSEKQVSYAL
                     KKITDLCQLVNEKELAVDIQVDGRVSLETIPGLLDAGATNLVLGSTSLFLKGNTLAEN
                     QKLLYQAMKQSVRKNQ"
     gene            1897..2646
                     /locus_tag="ACGXWR_002772"
     CDS             1897..2646
                     /locus_tag="ACGXWR_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFK0804242.1"
                     /translation="MLKLERHQKILDLLNAEQKVIASDLSQRFNVSEDTIRRDLKDLD
                     SQGLLKRVHSGALRVGPPITNFNYRETVASEQKTALAHKALPFLKEESVIIIDGSTTN
                     LALAKEIPQDFRATIITNSPPIAIALAQHPNLEIINIGGTFYKQSMINIGVQAYKQLQ
                     NIRADLYIMGIYNIDLDVGTSVPTMQESDIKREMIRISTEVLGMITNDKFGTISNHIV
                     GPIEDLTYLISEEIPEKVRKEYNKQKIVLID"
     gene            complement(2830..3075)
                     /locus_tag="ACGXWR_002773"
     CDS             complement(2830..3075)
                     /locus_tag="ACGXWR_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804243.1"
                     /translation="MSKSKKNITIIGLGLTVYLFTEFVYRHVNLFAEPLFVLYESNSS
                     IVSELANLMIALLFTPALRVITILVCLVLLFFVNKKK"
     gene            3395..4156
                     /locus_tag="ACGXWR_002774"
     CDS             3395..4156
                     /locus_tag="ACGXWR_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFK0804244.1"
                     /translation="MHTPEEIMELSIHLGTKKIHKPILAKLILGFIGGAMISLGYLAY
                     VRVSASIPESMASLTSLVGASVFPIGLLVILLGGGELITGNMMAVAIAFMDKKVTFSQ
                     LVKNWSVITFANIIGAIFVAYFFGHFVGLTHSGVYLDQVIHIADHKIAVSWWQALGSG
                     IGCNWFVGLALWLSYGAKDAAGKVLTIWFPVMIFVAIGFQHSVANCFVIPAAIFEGQA
                     TWLEFLSNFIPVYIGNIIGGAIFVSGFYYVSYKHH"
     gene            4384..4578
                     /locus_tag="ACGXWR_002775"
     CDS             4384..4578
                     /locus_tag="ACGXWR_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804245.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
BASE COUNT         1500 a          846 c          727 g         1583 t
ORIGIN      
        1 aatttctttt ttcaacacat cacttgcatt tatcacattt tcattagcta cgatattgat
       61 gctatgcttt tgttcaaatc gcttacttaa ggcttgcgca atgatcggtg caatttttac
      121 taaatttatt gcgccaacag atgttgttaa gatatctgca ttttttgttg ctgtaatcac
      181 ctcttctagc tcggataaac tattcagtgc cacaacatga tcaatgaaat cactcctgtt
      241 catttcatca ataatttcga tagtataacc cttatcttga tttaattgat ggatcagttc
      301 aggattcgta tcaataaaac atagatcgaa tccattctga tgtagaattt gtccaataag
      361 ccctctgccg atgttccctg ctccaaaatg taccgctttc atttttcacc tactctaagt
      421 tagcatggta ttgccacaac tttgacatat caattgcttt ttcttctatc atcactaaag
      481 caatactatc tcctaacaaa agaacacttt gttcaaacag gctagtcatt ggctgtatag
      541 aagaaatttc ctctggtaac gctaattttg tttgtacggg tatacgaata aaaagatctg
      601 aatattcttt cattgtgctg tctgggtttg atcctatatg ggcaacttgg gacccaaatt
      661 cctttgcttt ttttgcaata gttagtggga aagcactttc cccactacca gaaccaacaa
      721 tcaataaatc tttatctgta attgccggtt cagtgatttg tcctacgact actgtctgaa
      781 ttcctagatg ccctaagcgt tttgccattc cttctagcgc taacagtact ctgccaaccc
      841 ccacgaaaaa aactcgttcc gctttttcaa ttttctttat caattgttcc acatcttttg
      901 aagaaatacg gtctaatgtt tcagtaattt ctcttacaat attttgtttc gccgccttat
      961 aactcaacta tttcccctcc atttctatta ttcaggacca ctacatctat tgatttttcc
     1021 taactgattg cttcatcgct tgataaagta gtttttgatt ttctgctaat gtatttcctt
     1081 taagaaacaa acttgtactt cctaatacca gatttgttgc gcctgcatct aataatcccg
     1141 ggatcgtttc taacgatacc cgtccatcca cttggatatc tactgctaac tctttctcat
     1201 ttactaactg gcaaagatct gtaatttttt ttagcgcgta agaaacttgt ttttctgact
     1261 tgtttgttgc aaaacctgga ttaatcagca tcaaacaaat cctatcaatc tcgggtaaaa
     1321 tatattgtaa tacatttaac ggagttgctg gattcaaagc tatccctact tttgttccag
     1381 aattcttgat gagctggata tatcgatcaa tatggaggct tgtttcataa tgaaaagtaa
     1441 tgctctctac gccaattttc aacatttctc caataaaaaa ttcgttatcg ttatccttag
     1501 ccatgatgtg tacatcaaaa ttcattgaag tgatttctct aattcttttg attgtttcga
     1561 tccctaaagg catactggga ctaaaagaac cgtcaatcac gtcaatatgc aaggaatcca
     1621 tcccaatact ttctagttct tggatgcttc cttccaaatt tgctagatcc ccacacataa
     1681 gtgaaggcga caaaataatt tttttctcca tacattccct cctttaatta ccccctcatt
     1741 gtaaccgctt aacaaatact agtcaacata aaactgcata aaaatatttt gtttttgctt
     1801 gtttatgcct ttttagtgta ttaaaaacgg aaattattga cataaaaacg cataaatgac
     1861 atgataaaca agaataaata agaaggagca cgcaacatgt tgaaattaga acgtcatcaa
     1921 aaaattctag atttattaaa cgcagaacaa aaagttatcg ctagtgattt aagtcaacgt
     1981 ttcaatgtat ccgaagacac gattcgacga gatttgaaag atttggatag ccaaggtctc
     2041 ttaaaaagag tacacagcgg cgctttacgt gttggtccgc caattaccaa ttttaactac
     2101 cgagaaactg tagctagcga acaaaaaact gcattagctc ataaagccct ccctttttta
     2161 aaagaagaat ctgtcatcat cattgatgga agtacaacta acttggcttt agcaaaagaa
     2221 atcccacaag attttcgtgc aacaatcatt accaatagcc cgccgattgc catagcatta
     2281 gcacagcatc ctaatttgga aattatcaat attggcggta ctttttataa acaatctatg
     2341 atcaatattg gggtacaagc ttataagcaa ctacaaaaca ttcgagccga cctttatatt
     2401 atgggtattt ataacataga tctagatgtt ggaacgagcg tgccaactat gcaagaatcc
     2461 gacattaaac gtgagatgat acgtatttct actgaagtac ttgggatgat aactaatgat
     2521 aaattcggca ccatcagtaa tcatatcgtc ggtccaattg aagaccttac ctatcttatt
     2581 tcagaagaaa ttcctgaaaa ggttcgtaaa gaatacaata aacaaaaaat cgttttgatt
     2641 gattaagcga aaactattgg taactactaa agcaacagat ataaaaaatc taaaaaagaa
     2701 acacgcaata aagttttgaa ataaacttta ttgcgtgttt ccttttttgt ttattctcac
     2761 ttacctagca ccacgtataa catactatag caatcatcat cccacttctt tgtcttttga
     2821 aatactacgt tatttctttt tattaacaaa aaacaatagc actaaacaga ccaaaatagt
     2881 tatgactctc aacgcgggag taaacagcaa tgctatcatt aaattagcaa gttcactgac
     2941 gattgaggaa tttgattcgt ataatacaaa taaaggttct gcaaataaat tcacatgtct
     3001 ataaacaaat tctgtaaata aatatacggt taagcctaaa ccaattatgg tgatattttt
     3061 tttagatttt gacatttttt ctctcctata ataatttttt cagttattca tttccttttt
     3121 tataaaaaat gtagattgtt ttgaagtaat aatatgctgt agtttcaaga aaatttacag
     3181 gaaatttgat aactgatatt atttactttt tgaccaccat atacatgact tttatttttg
     3241 tttctttttt agaatcaaat gtgattaaat agaaaatttt acaataatat gcacatataa
     3301 ataataagat gatataatca acaaagaaaa tgtgattttt ttcactatat tttatcacat
     3361 gaaaattcat taagaaagta ggaatcgaag tattatgcac acaccagaag aaattatgga
     3421 actcagtatt catcttggaa caaaaaaaat acataaacct atcttagcta aactgatttt
     3481 aggttttatc ggaggagcca tgatttctct aggttatttg gcatacgtac gagtctctgc
     3541 ttctatccca gaatctatgg ctagcttgac tagtttagtt ggtgcctcgg tttttcctat
     3601 cggcctgctg gtcatccttc ttggcggtgg tgaattgatc accggaaata tgatggctgt
     3661 ggcgattgcc tttatggata aaaaagtcac attctcacag ctggttaaga attggtcagt
     3721 gattactttt gcaaatatta ttggtgcaat tttcgttgcc tatttctttg gacactttgt
     3781 tggtttaact cattcaggtg tctatctcga ccaagtgatt catattgctg atcataaaat
     3841 cgctgtttct tggtggcaag cattaggctc cggaataggt tgtaattggt ttgtcggttt
     3901 agcgttatgg ttatcatatg gagcaaaaga tgcggccggc aaagtactaa cgatttggtt
     3961 tccagtcatg atttttgtgg caatcggttt ccagcatagt gtggccaact gttttgtgat
     4021 acctgctgcc atatttgaag gtcaagcgac ttggttagaa tttctctcga attttatccc
     4081 cgtttatatt ggaaatatca tcggcggagc tatttttgtt tcaggttttt attacgttag
     4141 ttataagcat cattaagatt gaaggtaatg ttcattcgag cattaccttc aatctcttta
     4201 tatactattt atattttaag aacaatagcc ttttattata tatattattc aaattagtta
     4261 tatcgagtga aaaaaacttt caaattgatt ctttttattt atcataaaga tatagataca
     4321 taatcatttt cacttacata tatttgaata ttaactaaaa acagcaagaa agaagaggat
     4381 caaatgtatt atgtagaagt aaaaacaaaa ggcgtcaaaa acaaacaata tgtgaaaggt
     4441 atcagtaacg aatatccttt acttggttca tggaaagaag ctgctccttt ttccaaacca
     4501 tgtgccataa aaataaagaa cgagctagaa aaagaactga cttgtggcaa agctgttgta
     4561 gatatcatcg aaaagtaaat ccaatgtata gaaaggaaga tcacacatga aaagcgacgt
     4621 acaaattgct aagattatag aattagaaga agaaga
//
LOCUS       DAYNVV010000113         4505 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.118, whole genome shotgun sequence.
ACCESSION   DAYNVV010000113 DAYNVV010000000
VERSION     DAYNVV010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.118"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            544..1107
                     /locus_tag="ACGXWR_002776"
     CDS             544..1107
                     /locus_tag="ACGXWR_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFK0804246.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
     gene            complement(1386..1673)
                     /locus_tag="ACGXWR_002777"
     CDS             complement(1386..1673)
                     /locus_tag="ACGXWR_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFK0804247.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPNLLCGTHENFYEQLKKIR"
     gene            complement(1663..1992)
                     /locus_tag="ACGXWR_002778"
     CDS             complement(1663..1992)
                     /locus_tag="ACGXWR_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFK0804248.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            2297..2626
                     /locus_tag="ACGXWR_002779"
     CDS             2297..2626
                     /locus_tag="ACGXWR_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HFK0804249.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(2913..3398)
                     /gene="vanZ-A"
                     /locus_tag="ACGXWR_002780"
     CDS             complement(2913..3398)
                     /gene="vanZ-A"
                     /locus_tag="ACGXWR_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFK0804250.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(3551..4462)
                     /gene="vanY"
                     /locus_tag="ACGXWR_002781"
     CDS             complement(3551..4462)
                     /gene="vanY"
                     /locus_tag="ACGXWR_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HFK0804251.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT         1493 a          754 c          670 g         1588 t
ORIGIN      
        1 ttaaaacttt tttagcagat tttaaagttt cgtcaaaact aatatattct ggtagctgag
       61 cattcaaata gctttcagac ttcagaagaa aattacgagc atttttatag tccatctcta
      121 ataaagttat tcttttttta tccaatacat tcagctcaat tccttataat attctattcc
      181 ttagtatctc aacattattt actttataaa acgaataaat tttgtagttc taattcaaat
      241 attgcatgtt atatctaata tgggagcatt ttataatttt cattgtgata aactcgttat
      301 taactttagg atacactagt taggattaaa ttaggtatct agaaatttac ttaagatttt
      361 tttgtttatt tcgtatacac actcgtatca aaaacaatcg attatgagac aaaatgaaat
      421 gacctctttt attaaataaa agaggtcata ttttgtatca taacttgttg cattaactat
      481 gtatctataa ctccctttta tgatacaatc aagccagaat taaagtacga aaggaagaaa
      541 agcatgagtg gatacattta tggttatgcc cgagtgagta cacgttcaca agaactaaat
      601 cgtcaattag acttactcaa tgaacaaaat tgtaatgaaa tcctaactga gaaaatgacg
      661 ggaaccaaag cggttcgtcc ccaactaaat cgtttaaaag ataaaattcg tccgggagat
      721 acggtaattg tagaaagttt ttctcgattg ggtcgtagta caaaggattt gattgacctt
      781 gttacctatt ttgaagaaca ccatgttaag ctggtgagct tgaaagaaaa cttcgatacc
      841 agcacgcctc acggacgctt aatgatgact gtcttccaag catttagtca gttcgaacgt
      901 gatttaattg ttgaacgtac caaagaaggt ttgaaaagtg cacgtgcgag aggtcgtaaa
      961 ggtggccgtc cacgagtgaa ccagaaagat gttgatcgag cagtaaaatt gtataaaagt
     1021 caggtttata gcgtaaaaga aattacggaa atgactggta ttagcaaggc aacactctac
     1081 cgctacttaa aagacaatag ggaataatct attttaatct ttaggaatct ataatattta
     1141 tgggagaatt agagtgattt ttttattatt actaaaaaac aatataaaat aacgcatttt
     1201 aagccctctt tgtgcataag gatgaagctt ttaatttgaa agaggcttaa aatgcgtttt
     1261 aattttttct atttttcata aatatatagg ttagtggttt aaaattatag ggtattacaa
     1321 ctctcagctg ttaaaaatta tcttttaaag tgtcgtctat cctctcaagt tgaaacattg
     1381 ggttcttacc taatcttttt taattgttca taaaaatttt catgcgttcc acatagtaag
     1441 ttaggtatca ctgcattatc tttaatttca tatgcaacgc gatatgtcgt acctgcatac
     1501 ttgaatccaa tagcccaaat tcctgataaa tcacccgttt tttgttctcc cgaatgagga
     1561 cgaactgcta tctcatcata aattatcgtt aaaaattgtt cttttaatgt tttctctttt
     1621 aattttttta gatactttat tacgtgttta gaaggtagaa tctcataagc caatttctgc
     1681 tgccaactcc tcttttgtca tcggtttaga atttgcaaca gtatcttcag caatagattt
     1741 aaatgcagaa gttaacgcat tttttctatt tctaaattct tttaagatct cttgtttgct
     1801 ataaccttct gaaagaatat cagccaaaat atcttcacta aaatcaaaaa attctttttt
     1861 aggctctaca aactcataaa ggataccatt ctctacaagc ttagcttcta cttcaacacc
     1921 attgggcaca tcgaattctt tagggaccgt taacataata gaatttcctt gttttcttgt
     1981 ttttgtaatc atattatttc ctccattatt ttacatttcg taattactta gtaattacat
     2041 tgtacgctat ttttagtaga aatacaaaat aataaaactc ctttagaaca attttcaaag
     2101 gagttttatt tgattaggaa attatgtaga ataataatat gtttttaact tggaatcaaa
     2161 aacgcacttg caagtaagtt tacttcaata catgaaattg cttataatag tgtattggaa
     2221 ttaaggtaga ttgacaaaag agtgatcaaa taggtatact tcattcaaat aatcgtttga
     2281 atgtgaggtg agatgaatga aaaaagtttg ccaagtgact gtcgtacata aagaaaaagt
     2341 aaatggaata aaaaataaat tggatcaaaa agatttttca aacttacttg tgttagggaa
     2401 atgtttcagc gatttttcta gaattaaaat tttctatgct ttagaaacct ataaggaaat
     2461 gtgcgtctgt gatttagcag aaatacttac tgctagtgtc gctacaacgt cacaccattt
     2521 acgtttttta aaaaaacatg gaatggcaaa atcacgtcaa gatggaaaag tagtttatta
     2581 ctctttagcg aatgaagaca tcctttccgc tattcgtgtt ttttaaagtt atcagaaaat
     2641 ctatctatga aatcttagtt tgggggtacc gtcaggaaaa tgcggattta caacgttaag
     2701 gaaatttatt aaagagacca attcctcagc actaaaattg ataattgggc tttctttgtt
     2761 actatagtgt taggtaagct ttttacttta tcaccggttt tcccctcact tcacacctac
     2821 gggcgagttt ccccacatcc cgttttccat ctaatccaat tcattcaata tctttatgtg
     2881 tatgaaagat cagattgctt gatttagaca tcttacacgt aatttattct taaatgggta
     2941 cggtaaacga gcaataatac gagcaaaagt atacctacaa aaataataac tctgtctaat
     3001 tttttttgat tcatatgctt attgcttaaa ccatataatt tcagtccaag aaagcctcca
     3061 acagtatttg taattacatc tgttatgtct gtcgctccaa tagcgaagat aaattgaatt
     3121 atttcaaaag taagacttaa aaccagtaca aaagcaaact taggtaaaaa tccgatttct
     3181 ttaaaattga cattcaaaag caagccaaat ggaataaaga ttataacatt atctatcatc
     3241 tctctgaaat tcccagtagc agtaaatgga gtcaagttaa gacttctttg atgataatta
     3301 aatactgata aaatattgta ttgtaatttg aataacacta accagattag tgtcactaaa
     3361 tataaagcta gcaatcctct agataatatt tttcccaata taatttcctc taattctttt
     3421 gtttaagttg tatcattagt atagcaatgt cctagttaac gtgggtttta aattaaaaag
     3481 ctaacgttac cccaaaagtg ctagtacaat aatgctgttc attaatttcg ttggtttcat
     3541 tccgccatcc ttacctcctt gaattagtat gtgttgatcc gggaaacact gtcacaatta
     3601 caccgtctat attgtttcct gatatctcat aacgaagatt agtcggcaca tgaatggtgg
     3661 tatttttagt aacaggataa taaaagatct catatttttc cccatttaca ctaacagaaa
     3721 tggttttttc ttcttttagg taatccatat attcctcgag aacgaaattc ttttctttca
     3781 taatcgcact atgtggtaaa ccaacatagc gaatatgcca tagttcatat tgaattcctg
     3841 ttaactctgt tttgtcctct ggataacgta aaatgaaccc gtatttccaa gcattttctt
     3901 ctatccactt tccttcaggg gctcgttcca ttttcgtcaa gcttgatcct acatctagtg
     3961 ataaacctga attatgctca ctataacctg ctggtaaggc atactcagcc cccatttctt
     4021 ggtaaagcac actttgctca tcaaagtctc gatagccact attaataata aaatgactaa
     4081 cgccaccctt tacagcatca ttgaccatct ctgaaaattt ttgtgctatt tcttttgaca
     4141 tataaatatt actatcaagc aacccgtatc catttattaa ttcgtcatgt ttagataaat
     4201 tcacgatatc tgacttcaca ctttcttggc gaacaggata tttactattg attaatagca
     4261 gatttccttg ataaacctgt tcttctgtaa ttgttttctc ttgggtattt tcagaagtcc
     4321 cactattttc taaatgttct ttgggatttt gatcataatt ttgaaattcg actttttcct
     4381 gagaaaacag tgcttcatta acgtagtcat aacctaagta tattaagaat aacaataaca
     4441 ataaaaaaaa caacttcttc attttcagtc tcctccttaa ctatatagtt ggaagtatga
     4501 aatat
//
LOCUS       DAYNVV010000114         4504 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.119, whole genome shotgun sequence.
ACCESSION   DAYNVV010000114 DAYNVV010000000
VERSION     DAYNVV010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.119"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(97..1491)
                     /locus_tag="ACGXWR_002782"
     CDS             complement(97..1491)
                     /locus_tag="ACGXWR_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFK0804252.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            1583..2554
                     /locus_tag="ACGXWR_002783"
     CDS             1583..2554
                     /locus_tag="ACGXWR_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFK0804253.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            2551..3333
                     /locus_tag="ACGXWR_002784"
     CDS             2551..3333
                     /locus_tag="ACGXWR_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HFK0804254.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(3502..3873)
                     /locus_tag="ACGXWR_002785"
     CDS             complement(3502..3873)
                     /locus_tag="ACGXWR_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFK0804255.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            4007..4450
                     /locus_tag="ACGXWR_002786"
     CDS             4007..4450
                     /locus_tag="ACGXWR_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFK0804256.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
BASE COUNT         1477 a          708 c          890 g         1429 t
ORIGIN      
        1 tattttttga ggcactaccc gttgttgaac ctcgggtagt gcctcttttt tattgaaagg
       61 aatcaataag atttgattcc tttatttatc aataggttat aattcatatt tttttatttt
      121 ttcttttacg atacttagtc cagaagctaa aatttcaagg ttattagagg atagggaaat
      181 tcgaacgaat gcatctggtt gcgcacgtgt agtaaagcgt ctggaatgat aaagtcggat
      241 accgttagca agaaagtcat tctcaattat cttagggtca atctcaggat caactggaag
      301 aattcgatag taagggacac gattcgttgg tttttctact ttgaaaagag aatcaaaaag
      361 ctgattggct ctttttgtaa gacttaattt agtttctaag atcctatttg cttcatttga
      421 atggaggatt tgagtgatga cttccacatc taatccagaa gttttcacat ttatattaaa
      481 aattgcttgt tctatcttgc tttggacatg tactggaact acaagataag caactcgcaa
      541 tccagaacaa ataaattttg tcattccagc taagtagatt gtttggttag gtaataaatt
      601 ttggaaagga ggaatgatcg tatgttgata gtaagttgtt aaaaatgaat ggatatcatc
      661 ttcaataacc catagacctt ctttttcaat cacttcggct aattgctctc gtcttttgtg
      721 agagatttga aaccctatag gattattaca agaaggcata agaaagacac catgaatctt
      781 cttttttcta cattcctgaa tcaatatatc aggtcgcatt ccttgctcgt caaaatcaat
      841 tggaacgatc tctaaatgat ataactgagc caattcaatg aaattagcgt atgtatatcg
      901 gtctgttgct attctatcac ctggagagaa aagtgcagaa agtgtgatag ccaatccatt
      961 ttgaacaccg gaaacaatag atagagattc taaggacgga atgactcctt gagtttttaa
     1021 ccaatttgct gcagtagtca attgaaaatt tgtgcctttg ggatcttggt aattaagcaa
     1081 accaacaaga tttgggttat tactagttga ttgaataaac gggacaacga atttattaca
     1141 ttcttcaaaa gaactaacca gaccaaaatc aatgatatgt tcggttactt cattggtaga
     1201 gatggtgatg gactcaaaga cattgggaga aataaatgtg ccacttccaa tattcgtata
     1261 cagcaaacct ttctcaattc catatttata agccttgcca acggtagtaa aatttaaatc
     1321 taaataatca gctagctctc tttgggaggg taactgagtg tttttctgta atttattctt
     1381 taaaatatct tgttctaatt gttgaatcaa cgatcgataa taaggacgct tcaatttttg
     1441 tttgtctggt cgccaagtta acgggtaatt gtcataagaa ttaataggca ttttctccac
     1501 tccttaaaat tgtataccat acaattttac cattgattgt attgatttta gaagttaatc
     1561 ttttgtgagg agggaattgt ctatgaaaat tattaatttt gaggaagtag tagcttcttt
     1621 tagttttgaa gaagcgattc aagtaatgaa aaaatgtttt tttgattatg aaagtggtaa
     1681 aatcagccaa aatcctcgat tggtggaaat tttacctgac ggaaaaggca aaaatatgtt
     1741 tgcgatgatg cctgcttatt tgggggagaa cagatatttt ggcacaaaag tcattaccgc
     1801 ttttccggat aatcatcagt atcatttacc ttctcattta ggagagattt tcttgtttga
     1861 tgctcaaaac ggactaccca aagcattgat aaacgcaaat gcagtcacct ggattcgaac
     1921 agctgctgta tctgcgctgg caacagatta cttagcaaat ccgcatgcag aaacacttgc
     1981 tttaattgga gctggtcaac aagcattgtc gcatttgact gcgatttcta ccattcgtcc
     2041 catcactaca gtgtttgttt acgatatttt agaagaaaga cgaaatactt ttatcgctaa
     2101 agctaaaaaa cagtatccta aaataacgtt tataaatgca atatcagtag aagatgcagt
     2161 acgtccagcg gaaatcattt gtacgttgac ctctagtaaa gaggcatttc ttcaaaaaga
     2221 gtgggtaagg gaagacgcac atatcaatgc tgtgggcaca tttactcctg atacaagaga
     2281 gataagtaca tcgttgatgg aaacttctca aatctatgta gatgattact cagctgcctt
     2341 aacagaaagc ggggacctgc ttatagccat ggcagaagga gatttagagg aatcttgtat
     2401 tgttggtaca ttaggcgaat tagtttctga gaaaaaaaca ttttataaag gagaatcgag
     2461 gccgacgatt ttcgacgcag ttggtctagc tattgaagat ctttgttgtg cagaatatat
     2521 ttataacaaa ttagagaaag gggctttaaa atgaacttag attattacgt agttgatgca
     2581 tttgcagatg aggtgttcaa aggaaatcca gcagcggttt atgtgctaga agaatggctg
     2641 ccagaaggta cgatgcaaaa aattgccatt gaaaacaatt tatctgaaac agcatttaca
     2701 gtgaagaaaa accaagaatt tgagcttaga tggtttacgc cagatcgaga aatcgatctt
     2761 tgtggtcacg cgacattagc aacagcattt gttttattta actattacaa aatacctgat
     2821 gaaacgatta aattttctac tcaaagcggt aatctatttg tgacaagaat taaagattat
     2881 tattacatgg attttcctag tattatgccg aaaaaagtgc cgatattgtc tgaatatgaa
     2941 gaagcgattg gggctaagat taaagaagcc tacttagcac gtgatttatt tttcgtatta
     3001 gaagatgaaa aaacggtggc taaattgcag ccagatttta cagctatcaa aaattttgaa
     3061 ttaggaatag gagtcatcgt gacagcagaa agtgtgcaaa aagactttgt ttctagaacc
     3121 ttctttccaa aattaacaat caatgaagat ccagtatgtg gatcagcaca ttctaatctt
     3181 attccttatt gggcagaaag aatgaataaa acaaaattgt cagcttatca aatgtcatca
     3241 aggggcgggg atctagaatg tgaattaaaa gaagatcgtg tgataatagg aggaaaagca
     3301 gttttgtttt ctaaaggtac ctcgtttatt tgatttcttt caaatgaatt aaaaataaat
     3361 tggtggagag tggcaacctt atagctacaa tggttgttaa aaaaagacgc aaactttttc
     3421 aatttaatga aaagtttgcg tctcatttta attattggtg tttgtttttt attcaatcaa
     3481 gagtaaaatg ccccatacta actatcctcg gatgacttcg attttataac catcagggtc
     3541 aatgacaaag tagtaagaag gcgcagtgcc aggtaatcct tttaagtcag taatctcaag
     3601 accggcagct ttatgttgct cgtgtaattt ttctagatca tcagctgcta tagcgatatg
     3661 accatagccg tctcctagat catacgcacc atgatcatag ttgtaagtca actctaattc
     3721 atagtcatcc ccaggaagtg tcaaataaac aagtgtaaat ttgttttctg gaaaatcacg
     3781 gcggcggctt tcttcaaaac caaatgcctt ttgataaaat tcgattgatg cttcaagatc
     3841 tttcactcga acacatgtgt gagccatttt catagattca tctctccttt tccttttact
     3901 caatcataac aaaaagaagt aaggaaatag ttgatttgtg cttgttcatg agaaatttct
     3961 catgtaaaat ggatagaaaa taaaactgtt aaggtggaaa ctattcatgg ataaaccaat
     4021 ttttggtgaa aaaaagcaat ttgctgatta tcaaacccgt tatgcagcat atattgtcat
     4081 agaaagagat cagcagattg cagtaatcga ggctccaaat ggtgcttttt ttcttcctgg
     4141 cggggaaatt gaaggagaag agacgaaaga agaagcgatt gtccgtgagc tgatagaaga
     4201 aatgggaatt gtggcagaaa tttcttctta tctgggagaa gctgatgagt atttttactc
     4261 gaattatcgt gcaacttatt attataatcc aggatatttc tttgttgctg attcttggaa
     4321 gcgtatagga gaaccaactg aaaagaccaa taaaatttgg tgggtgagcc ctcaagaagc
     4381 gcttgtgaaa ttgaaacgtg gtagccaccg atgggcagtc gagagatgga tcgaaaaaaa
     4441 taaaaactga aagaaagcga gtagatcagc tttctctcag tttttttatt tattacagta
     4501 cata
//
LOCUS       DAYNVV010000115         4477 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.120, whole genome shotgun sequence.
ACCESSION   DAYNVV010000115 DAYNVV010000000
VERSION     DAYNVV010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4477
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.120"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            326..1054
                     /locus_tag="ACGXWR_002787"
     CDS             326..1054
                     /locus_tag="ACGXWR_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFK0804257.1"
                     /translation="MKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEAG
                     DEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYAA
                     ADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAVS
                     LVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYQFGANENENQDAVQLSVP
                     GKSVKLAQQYSTKLVWTLEDTPNN"
     gene            1199..3226
                     /locus_tag="ACGXWR_002788"
     CDS             1199..3226
                     /locus_tag="ACGXWR_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HFK0804258.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGHSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            3334..4431
                     /locus_tag="ACGXWR_002789"
     CDS             3334..4431
                     /locus_tag="ACGXWR_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFK0804259.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
BASE COUNT         1575 a          717 c          924 g         1261 t
ORIGIN      
        1 aaaaaatata atatacattt tttatttaat tataattaat attgattgaa gtctaggcag
       61 tcaagtcaca ttttgataga taggaggggg acttacgaat tattttaaag gctatgacag
      121 ctgtatttct agattgtgtt tgcatcaagt tgcaataaaa actagaaatc aaatcgggct
      181 gataatcatt tataactaat cgatacatag gaccaaatat aggtctatgt tcttttattt
      241 cataagtatc gtaaaacaga attttgctat ggattaatcc aatcgactga tatgtttagt
      301 aaataaagaa agaggaatgt caatgatgaa aaaagaaatc gtattaacag cagcaatgat
      361 gttattcagc atggtagcaa gtacgacttt tgtttctgca actgaagtat acccaaagga
      421 atataacaca gaaggaacga ttacatttga agcaggagat gagggtgtaa ctcctcctgt
      481 tgatccagag aatcctgatc ccaataaacc tgtcgatcca tcagatcctc caagccctgg
      541 aacaggaggg gcattatcga ttgattatgg atcaaaattc aaatttggga ctcaaaaaat
      601 ttctactgcg gataaaacgt attatgcagc tgctgatgtg atgaacgatg ggtctagaaa
      661 accgacatat gtccaagtga cagataggag aagtacctta tctgggtgga aattaagtgt
      721 ctctcaacca gaacagttta aaactgccag tggggatgaa ctagttggag cacagctgaa
      781 atttacgaaa gggcaggctg tttctttggt tgatccaaca tatacgccgc aaacggtgaa
      841 ttctgaatta acgttgacac cgggaggaaa caatacgtta gcaattaatg ctaaatcagg
      901 aacaggtgtg gggacttggg tctatcaatt tggtgcaaat gaaaatgaaa atcaagatgc
      961 ggtacagctt tcggtacccg gtaaatctgt caagttagcg caacaatatt ccactaaatt
     1021 agtttggaca ttagaagata cacctaacaa ctagtttact gaaaagaact gttaaaaata
     1081 aatacgtagt catattgtct tgcgaggtaa tcgagcaaaa attgtcaaag gctaggctaa
     1141 atttgtttgg atacgaatag ttcatctagg aatttaacga tcaggaggaa aagatatatt
     1201 gaaaaagagg aggatcgtgc tcattttaag cagtctctta gtgactaata tctttccgat
     1261 catagggtac tctttggaat tgaatcagtt ggagcatgga aatagaagag acgaagaaag
     1321 caaactcact tcgacattcg acagtttaat agaatccaac cagacacaag aaagcagtga
     1381 ggatttaagt atttcgagta gtggagagac cactgacaac gtagaagctg agggttcgga
     1441 caaacaagga ctagaagatg caccaatttc tgcggttgag ctgcctgacg atcccaatat
     1501 tatttctatc gataaaattt ttcaaacacc tatcggtact agcacgtcca tattggaaaa
     1561 tgggaagtta ctgcagttga acccagcaga aaggtctcaa agaggagcta tttggtcaaa
     1621 taagaagatt agtttactct cggattttac atttaaatct tatttatact taggaaatca
     1681 acgagataga gcgggagatg gcatgacctt tacattgact ggcgatccta gaatggctag
     1741 taatcccagt caagttattg gatcgccagg tatgggaatt ggctcatatt ctactcgttc
     1801 tggccaacct tacattgcga atgcgctctc gattgagttt gatacgtata aaaatagtgg
     1861 ttcttctgat cgaatggatc gagagataac tgctgataat agagggcatg gacatgtcgc
     1921 ttttgtcacg cctaaaccaa ataataataa ttattctgga gagcatactg gcgtgacggt
     1981 agctcctaca tttctttcta atggcacatg gcgcttgtta ataattaaat gggacgcgga
     2041 gcaaagaagt cttacttatg atttggaagg tgtcggtcac tcttctcgga ttatacctga
     2101 tctcattagg cagtttggtt ctacagaagt aaattggggg tttacttctt caacaggtac
     2161 tttttttcaa gaaaatgctg tcgctgtcac gcgacttcca tcgaatgtca catcaacagc
     2221 tgatgtaaaa gtcaacgata gtgattatgg ggccatcgct gaagctggag gaaacgataa
     2281 gataactatc agaaatacat tgaaggtcga gggggatttt cttgaatata agaaaatgca
     2341 gactagtatc gacctcccac aagaattaac tattcccgag catatcttga tcaatggaaa
     2401 tcaaattgat gccaaagata tcttgataac cggaaatcga gtcacgctaa atctgacaga
     2461 ttattttatt gctggagata cgttaataat cgaattggag acaactttgc aggaagtaat
     2521 tcctgaaaaa gtactcacta tgcattttga ataccttgaa aacgggaatt tgattgagca
     2581 atcgaatgaa ataaacctaa agatcgcaaa gctgaaggag atagatatcc atgtttatta
     2641 taaagataaa gacagtcaga ttgatattgc tgaaatgaaa acaatcactg ggaaaatagg
     2701 agagaagtat aaagaaactc ctattgatat tgaagggtat gtttttgact cggattcagc
     2761 gaatacagaa ggcatcttct ccgaaaatac agaggatatc tatttttatt acagaaaagg
     2821 caaactttat ctctcaactg ctcctcaata tgtcaatttt ggaaaacata aaatatccag
     2881 tagaccatta agtgaattcg gacagttttc aggtgggttg aaaattatag atgaacgggc
     2941 ttttggaagt tggaaattac aattgaaaca agagaaagtt cttacaaatg gagattttga
     3001 gcttccagaa gctctttcct ttgttacctc tgaaaataca acggttatag ggacatccgc
     3061 tgttacgatt ttcgaaagtg atcaaaaggg tgaaagcgat ttgtcctctc ttttagattc
     3121 tacagctcat cgtggaatca gaatagatat tcctgtagaa aaccaaagaa tcggaacctt
     3181 tgaggggaaa ctatcttgga tacttgcaga tgtcccagga aattaacagg aagagaagaa
     3241 tataacaaaa ttattgagtt tcaagaaggg cacaggtacc ataggctctt gtgtcccaca
     3301 gagacaagat tttgttatag tcttctctta catatgatta aaggagcgat tttcttgaga
     3361 ccaaaacaac aattatttat aacactccta gttattttag gggcactttt taacaatata
     3421 tcagtgtcag ctagtgcatt taatttttca gtgacgccga taacttcaga gaatcaaatc
     3481 gacaagagaa aaacttactt cgatcttcaa cttgatccgg atcaggaagt agaagtaaaa
     3541 gcggaattga gaaatgatac agaaaaagaa gtgaaaatcg atatttctgt gaatagcgca
     3601 accaccaatt caaatgtgat ggttgaatac ggaaaaaacg agattgaaaa agacatgagc
     3661 ctgatctttg atctggtaga ttatgtgagc tatccacaga tagtgacgct aaaacctaaa
     3721 agtgtccaaa ccgttgcttt tcatgtcagg atgccgaatg agcgatttga tggtgtattg
     3781 gctggtggga tcacattcca agaaatccag acggaaaagg accaaacaga aactaaggat
     3841 caaagcttat cgattgagaa tgaatacacc tatattattg ctttgttgat gcaacagaca
     3901 ctgaacgaag ttgctccgaa ccttactctt catgaagtta aaccagatca aatcaatgca
     3961 agaaatgtca tcttagcaaa cgttcaaaat gatcaaaaaa cctatatcaa tcaagtagtt
     4021 attgaaacaa aaattacaaa aaaaggacat tctgaagttt tatatcaaga ggaaaaagaa
     4081 ggattgcaga ttgcgccgaa tacaaatttt tcttttccaa ctgctttaaa tggtcaaccg
     4141 ctaaccccag gtgaatatca ccttacaatg actgttttag gaaatgaaaa tgaaaatgga
     4201 aaattttcga gaaaaaaagg aaatactacg atcaactata ccaatcaatg ggtatttgaa
     4261 aaagatttta caatagacgg aaaagtagcc aaggaattga acacgacgga tgttacgatt
     4321 aaaaaagaca ataattggat ttatatctta gtagcttcac ttttcttatt gtttatttta
     4381 ttatgcatac ttttgtttgt tttgagaaaa aaagaagaga aagaaaagta aggttaagat
     4441 aacaaatagt aaatttttat tattgtagga tggttgg
//
LOCUS       DAYNVV010000116         4461 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.121, whole genome shotgun sequence.
ACCESSION   DAYNVV010000116 DAYNVV010000000
VERSION     DAYNVV010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.121"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            574..1008
                     /gene="bacA"
                     /locus_tag="ACGXWR_002790"
     CDS             574..1008
                     /gene="bacA"
                     /locus_tag="ACGXWR_002790"
                     /inference="COORDINATES: protein motif:HMM:NF041453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin 51 precursor BacA"
                     /protein_id="HFK0804260.1"
                     /translation="MKNKIIKIITCLFLFGMIVGASTPLNLFPFSARGIKVEAASSRY
                     NHNHRGFTCYKMNYYVTNKMCRDLKKNYNKLKTPAQIASFIPIGGVGTWVITNAFSSA
                     VDAMNVFVRAANQGKGVQLTYNAHFSNTTSYQYNDYARYVIK"
     gene            2298..3221
                     /locus_tag="ACGXWR_002791"
     CDS             2298..3221
                     /locus_tag="ACGXWR_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFK0804261.1"
                     /translation="MANEIVKYENRLNHIPLRKFNSREMNLFFSIASRVREKGVDEII
                     FSFHDLKKLSGYTERGEQFIKDLSSTYDKLLSINAWNDDGNTLTKFVAFTKYSIIRDK
                     QLVIISVNPEFKGLFNQLKNWTRFNLEQFTNLDSTYSKTMFRLLKQYRTQGWTEFSKE
                     KFFDLLDIPKSYWNSPSNIDKFILRPIKEELTPLFKGLTIRKKYGKGRGKPVIGYRFT
                     WKAEINHADDFSKGKQEDLRIKLFNIDHNGELTREEKWRAKDRILNLPLGTHEADFKQ
                     QQQTEEKQAEKRELSNKLKQDLLGNLQNLFD"
     gene            3237..3776
                     /locus_tag="ACGXWR_002792"
     CDS             3237..3776
                     /locus_tag="ACGXWR_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFK0804262.1"
                     /translation="MADKTIKELAEELGVSKTAINKKVSDKNRKLWFAKNGNKFVINE
                     TGQKAIKSMFLVDNANLNRKLVGEKSKTKNHKNTNQVSELKLLSFLEKQLNRKDIQLQ
                     EKDNQIKQMQKLLDQQQQLTLQANQQIENLQEQLHLTYTEETPTTESTAFSEKKADNT
                     QPLIEKKWWQIWKSNRTNL"
BASE COUNT         1664 a          667 c          758 g         1372 t
ORIGIN      
        1 aaaaaaaact gtgttggtac tgggttctat ttctctagga atattaggtt ttagccccat
       61 gctattatcc gtaattggaa aaaacaattc caacagagaa cttaaattga attcaaatta
      121 ttacaacagt cctaacgaag aattgtttgt aaaagaaacg gataaataat aaaaaagact
      181 gctcttccga gcagccagtt aaaaaataat gagtgtttat tcttgaaaaa gcaacgcgct
      241 tataaagcgc taccaaaaat ttatcatatt ttatgaaaaa taacaatcca gtaaaaaatg
      301 actggtaaaa attcacaaag aaacggaaag aagcaactgc agaaaatcaa gccttaaaaa
      361 gagcttttta cctagaccaa ttaaaaatca caaagtgagc ccctgtatcg gttgatacaa
      421 gggctacttg gcatactgta cattatgtct actaaccttt aaaataacac gttttataaa
      481 ataaaccctc ttgacaatat ttaattttct gattattcta aatatataca gaaagcgctt
      541 tcctaggatt ttatatctaa ggaggaagta acaatgaaaa ataaaattat taaaattatt
      601 acttgtctat ttttgttcgg tatgattgtt ggagcaagta ctccgttaaa tctgtttcct
      661 tttagtgcta gaggtataaa agtggaagct gcaagttcac gatataatca taatcatcgt
      721 ggatttactt gctataaaat gaactattat gttactaata aaatgtgtag agatttgaaa
      781 aaaaattata ataagctaaa gactcctgct caaattgcat cttttattcc tattggtgga
      841 gttggaacat gggttattac aaatgctttt agtagtgctg ttgatgcaat gaatgtcttt
      901 gtaagagctg caaatcaagg aaaaggtgta caattaacat ataatgctca ctttagcaat
      961 acaacatcat atcaatacaa tgattacgct cgttatgtaa taaaataatc agaaagtgaa
     1021 actatctcat gaataaaaag attttagctg taattatttc aataatagtt ttaatcacta
     1081 tgttcttcat atttaggcta attttcaata taagcttaca aaaaagtatt ctttatctaa
     1141 ttcctatagc atttatctta gcaattttta gaagtattta cggaaataaa aactctaaat
     1201 agctaaaaat aaatcatact aaattttaca aaaagtggct agcattttct agccactttt
     1261 tgtattgtgg agcgtgggtt ttgaggggga ttcaaggggg agcttgcgcc cctttgacaa
     1321 gcggttattt gcaccaaata cggaggtatt tggctagcaa atatagagct tgccaaaccc
     1381 ttttagtgag ttttgtagaa agtaccttta aaggtacttt cacattacga acgatacgtc
     1441 cgtaggacgt actgaaaggg tgggacttat gagcaaatta atgcaaaatt tggctagcaa
     1501 aaaagctaaa aaatatatgc taataatcga gcgaaataaa cactttttca agtgagcgaa
     1561 tccgccatga caaagctgaa gcagtttatt tcagctttgt catggcgtgt gccgactttt
     1621 ttaaaagtct aggcacacga gcaaatatct ttatcaagct ctaatttgcg ttttaagacg
     1681 tttgaaacgc ctaagtatat aaatatataa gaataggttt aagagtgctt aaatcgaatt
     1741 ttagagggca tttagacaat tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg
     1801 ttttaagaac aagataaggg atttatacta ggactgtctt aaaatgtctt aaacgaacgc
     1861 tcagagcttc tcaaagggtt ccttatgaac ggcttttagc aaaggagccg gaggcgactg
     1921 cgcagtataa tgtgagagca gagcgatcac acctttttag cgaaccgtag ggagcaaggt
     1981 ttggaattgg cagttttgat aaattcgcga acctgtttag agaaaaaagg agtgattttt
     2041 taggcgggaa aattagcctc ccctcttttt atatctcttt ttatatctct ttttatatct
     2101 cttttatgtc ggctgtgtcc ttactctccc aagcaattca gagttttttc aagtaggttt
     2161 tctacgcttt tcaagtaggt tttctacgct tttcaagtag gttttctacg cttttcaagt
     2221 aggttttccg acattattga gtatttttat aaagtatgtt acttttattt catactttat
     2281 aaaagtagga gaagcttatg gcaaatgaaa ttgtaaaata tgaaaataga ttaaatcata
     2341 ttcctctgag aaaatttaat agtcgtgaaa tgaacttatt tttttcaatt gcttcacgtg
     2401 tacgtgaaaa aggtgtagat gagattattt tttcatttca cgatttgaaa aaactaagcg
     2461 gttatacaga acgtggggaa caatttataa aagatcttag tagcacgtat gacaaattat
     2521 taagtattaa tgcttggaat gatgatggaa atactttaac taaatttgtt gctttcacaa
     2581 aatatagcat tatacgagat aaacaacttg ttataatttc agttaatcca gaatttaaag
     2641 gactttttaa tcaattaaag aactggacaa gatttaatct agagcaattt actaatttgg
     2701 atagcacata ttcaaaaact atgtttcgat tattaaaaca atatcgaact caaggctgga
     2761 ctgaattttc caaagaaaaa ttttttgatt tactagatat tcctaaaagt tattggaata
     2821 gtccgtcaaa tattgacaaa tttatcttaa ggccaattaa agaagaactc actcccttat
     2881 ttaaaggatt aactattcgt aaaaaatatg gtaaaggtcg aggtaaacct gttatcggtt
     2941 atcgttttac ttggaaagct gaaattaacc atgctgacga tttttccaaa gggaaacaag
     3001 aagatttacg tataaaatta tttaatattg atcacaatgg agaattaaca cgagaagaaa
     3061 aatggcgcgc taaagatcga atactaaatc ttcccttagg cactcatgaa gctgatttta
     3121 aacaacaaca acaaactgaa gaaaaacagg cagaaaaacg agaactttca aacaaactca
     3181 aacaagattt actaggaaat ttacaaaact tattcgatta agcttaagga gtatttatgg
     3241 cagataaaac aatcaaagaa cttgcggaag aattaggagt tagtaaaaca gcaattaaca
     3301 aaaaagtttc tgacaaaaat cgaaaacttt ggtttgcaaa aaacggaaac aagtttgtga
     3361 ttaacgaaac cggtcaaaaa gctataaaat caatgttttt agtcgataac gcaaacttaa
     3421 atcgaaaact agttggcgaa aaatcaaaaa ccaaaaacca taaaaacacc aaccaagttt
     3481 ccgaattaaa actcctttct ttcctagaaa aacagttaaa tcgaaaagat atacagctac
     3541 aagaaaaaga taatcaaata aaacaaatgc aaaaattact cgaccagcaa caacaactca
     3601 ctctacaagc gaaccaacaa attgagaacc tacaagaaca gctccattta acttatacag
     3661 aagaaactcc aacaaccgaa tcaactgcct tttctgaaaa aaaagcagac aatacacaac
     3721 cacttattga aaaaaagtgg tggcaaattt ggaaatctaa tagaaccaat ctctaaaatt
     3781 ttctagaagt tagttcggat agtagaggaa aaagttgtac tacctgatgg ggagatcact
     3841 caaattttta tgagaaagaa aaaatagttt acaactgtaa acaatcaatg tttatagttg
     3901 taaactatca aactatatgg tgacttattg cttaaaatag gttgaaatct cactcaattt
     3961 ttggtggaaa aacaaaataa attctaatcg attttgttga aaaagtcata aaaaaacaaa
     4021 tgtgatttta acaaaatttc aaaaaaatcg tttgaaattt cgtttatttt ttttgagaat
     4081 tttgatcatc gtagggtcat tgtagaatca ttatgagatc atcgtgggat catcgaataa
     4141 agtatgggaa aggcttgcgg tgcttggtat taagggcatt ctccgcctcc caggttcttg
     4201 accattttct cttataagtg ggatttttac cacgttgaga gaaaatggtc aagaacctgg
     4261 gaggcggaga aaacatacca agcaccacaa gcaaaaaaag ttagagtaac ttccaaaaaa
     4321 gaaaaatttt ttagaacaac ttttgaaaat ttaattttga tttatatccg ttcaatttaa
     4381 acatttgata aactgaaggc tagtatttaa aatgtgtata caagtggtag cgttaaaaaa
     4441 agtggaggta taacctatgt t
//
LOCUS       DAYNVV010000117         4461 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.122, whole genome shotgun sequence.
ACCESSION   DAYNVV010000117 DAYNVV010000000
VERSION     DAYNVV010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.122"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(44..1600)
                     /gene="rny"
                     /locus_tag="ACGXWR_002793"
     CDS             complement(44..1600)
                     /gene="rny"
                     /locus_tag="ACGXWR_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HFK0804263.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(2011..3060)
                     /gene="recA"
                     /locus_tag="ACGXWR_002794"
     CDS             complement(2011..3060)
                     /gene="recA"
                     /locus_tag="ACGXWR_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HFK0804264.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(3169..4410)
                     /locus_tag="ACGXWR_002795"
     CDS             complement(3169..4410)
                     /locus_tag="ACGXWR_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HFK0804265.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
BASE COUNT         1142 a         1012 c          779 g         1528 t
ORIGIN      
        1 aagagctgtg gcttttgccg cggctcttct tttgtatttt ttattattta gcataatcag
       61 ttgcacgagt ttcccgaata acgattactt tgatgtgtcc aggataatcc agttcttctt
      121 cgattcgttt acgaatatca cgtactaaac gaacagcgtc taaatccgag atttcttctg
      181 gcttgaccat tacccgaact tcgcgtccag cttgaactgc gtaacttgat tctacaccgg
      241 cgaagctgtt cgaaatattt tccagacttc ttaaacgacg gatgtagttt tctaatgatt
      301 cacttcgcgc accaggtctt gctgctgaga gcgcatctgc tgcagctaca aggacagaga
      361 taacagaagt agcttccaca tctccatgat gagaagcgat cgcgttgatt actactgggt
      421 tttctttgta cttggcagct aattccgcac cgatctcaac gtgagatcct tcaatctcat
      481 ggtcaagtgc tttcccaata tcatggagca acccggcacg ttttgctaat tggatatctt
      541 cgccaagctc tgctgctaag ataccagcta attttgcaac ctcgaccgaa tgcttcaaga
      601 cgttttgtcc ataactagtt ctgaatcgca gacgtccgat gatcttgatt agatctggat
      661 gaagtgtatg agcaccgact tcaaacgctg cctcttcccc gtattcgcga atacgttcat
      721 ccatttcttt acgagatttc tcgaccattt cttcgatacg cgctggatgg attcgtccat
      781 cttgtatcag tttttccaag gtcatccgtg cgatttctct tcggattgga tcgaatccgg
      841 aaagaacaac tgcttccggt gtatcatcga tgattaaatc gataccagtc agcgtctcaa
      901 gcgttcgaat attacgacct tctcgtccaa tgatacgacc tttcatttca tcattcggaa
      961 gggtaacgac tgaaacagtc gtttctgaaa cttgatctgc tgcgcagcgt tgaatcgcta
     1021 atgataataa gtttttcgct ttgcgatctg cttcttcttt ggcacgctgt tcagattctt
     1081 ttaccattag agttaactca tgattcagct cttcttcagt cgatttcatg atgacatctc
     1141 gtgcgtcctc ttttgataaa ccagcaattt tttctagttc tttttgttga tcttcaatca
     1201 ttttttcaac gtctttttct cgctcttcaa ttaattgctg ttttgaacta agtgcttctt
     1261 ctttactttc aagtgagttc tcgcgttttt ctaacgagtc atctttacga ttcagcgttt
     1321 gttcgcgttg aatcaaacga ttctcttgag attttaattc taacttactt tctctcagct
     1381 cactttcaac ttcagaacgg tatttctgat tttcttcctt agcttctaac aatgcttctt
     1441 tttttagagt ttctgcttct ttttttgcac tatcgatgat tccagcagct gatgattgtg
     1501 caccagctat ttctttctcg tgacgtgact ttgcgaccat aaaccctaaa ccaagaccga
     1561 caattaaacc gatgatagcg aggagaatgt tgaataccat aaaatccacc tccatactat
     1621 ctttttcatt tttatcatct atacagcttc tatgataaat tattctaaac tcgtcaatat
     1681 gcatcttcgc atatatgtgt acaaaaaaca tgcacaactt tattctaatg tttgtacccc
     1741 gtagtgtcaa ctttaaataa acaaagaaac ggctttctac ttattcatta aacgatggtt
     1801 tttaaaataa atgacactag tttcatatag gtaaaccttt aaattgagaa acttttctat
     1861 taaattattc tttgtagatg aacagatatt tttattttat gtacccactc gtataattaa
     1921 ataactcacg atttctttat tcaataaaaa aacggcaggt caaggagagt acctactctt
     1981 cagaccagcc gtttttgttt atcataattt ttattcttct actaaaggca attcttcttg
     2041 tcctttttca tcttctggga cagcgacttc ttcaccaata ccataagctg ctctaactag
     2101 agcagaaact tctgccatca tttcaggatg attagccata tagattttag cgttttcccg
     2161 tccttgacca atccgatctt ctttataaga ataccaagca ccgcttttat caacaatgtc
     2221 tttttctact gccatgtcta gaagttctcc ttcttgtgag atccctaaac catacatgac
     2281 atctacttca gcgattttga aaggaggtgc tactttgttt tttacgactt tgatctttgt
     2341 acggttacca acaatatctg taccttgttt caattgttct gcacgacgta cttccaaacg
     2401 gatcgttgcg tagaatttca atgcgcgtcc tccaggagtg atttctggat tcccaaacat
     2461 cacgcctact ttttcacgga tttggttgat gaaaatagcg attgtttttg ttttgttgat
     2521 cgaaccagag agtttacgca atgcttgaga catcaaacgt gcttgtaacc cgacatgtga
     2581 gtcacccatt tcgccgtcga tttctgctcg tggaactaaa gcagcaactg aatcgactac
     2641 tacgatatct acagccccac ttgatactaa agcatcagcg atctctagac cttgttctcc
     2701 tgtgtcaggc tgtgaaagaa gtagttcatc gatattcaca cctaattttt gtgcatattg
     2761 cggatctaac gcatgctcag catcaatgaa agcggccgtt ccgccatttt tttgtacttc
     2821 tgcaatagcg tgtagtgcaa ctgttgtttt acctgaactt tcaggtccat atacttcgat
     2881 gatacgtcca cgggggtaac cgccgacacc taaagcgaca tctaacgcaa gagagccact
     2941 tggaattgta gagatttgtt ggtcgatttt ttcgcccaat ttcataatag agcctttacc
     3001 atagctcttt tcaatttttt tcagtgcagc atctaaggct gctttacgat catctgccaa
     3061 tacgataatc ctccttatat ttacaaatca gagcaacatt tcattatcct tatcatatct
     3121 tttttagtga aaaaaagcaa gaaaaaaccg aacaaatatt cgcatttatc attttcttaa
     3181 aagctgtttt ctcaaaagat caaatccttg cataaccgca ttatatctga tagcagcacg
     3241 atctctggca aagtgatatt tttccgaaac cacgccgtct ttagatgaaa tagcgatcca
     3301 tactgttcct gcagattgac cttctaacgt gtccggtcca gccactccgg tgaaagctac
     3361 actgtaatct gttcttgcta tctcacgtgc ttgaatggcc atctgctcca cacattcttt
     3421 gctgactgtt ccatattctg ctaatagctc cggatcaatc tccagaaaac cagcttttgt
     3481 ttggagcgag taggtaacga atccgcctgg aaatacttca gatacaccag caatgtcgcc
     3541 taatgcggct tggaaggcgc cggctgtcaa actttccgct gctgttacag tctgcttgtt
     3601 ttctttcagt agttccacta cgacttttgc tagcgaatta tcatcgccgt atccataaaa
     3661 atattcccct actcgttctt ggattttttc ttctaatgct aaaagagctt gattccctgc
     3721 ctgaacatca tttgttttca ctgtcagtcg taatgtcact tcatttggtt tggcatatgg
     3781 tgcgatcgtt ggattgatct gtgtctcaat cagatctttt agctcagtga ccagtcgcga
     3841 ttcaccaatc ccataaaagc gcaaaacttt agaaattagt ttttcttcag aaggaaaacg
     3901 ttcctctagt aaaggacgta cttgttccac aaacattggt ttcaactcat taggcggacc
     3961 gggaagaagg atatacgcat gtgtatctgt ttgataaaaa gtccctaaag caagccctgt
     4021 acgatttggt agaggaaccc cgccttcgat aatctgggac tgttgcagat tgtttttggt
     4081 catttttcga tgggttgttt caaaatatgc caataatttt ttgtatcctt ccgtattttg
     4141 tatgagagac ttaccgaggt gagccgcagt tgcttctttt gtcaggtcat cttctgtcgg
     4201 tcctaatccg ccacataaga gtatgagttc acttcttgtt tcagctagag caatcaactc
     4261 ttctaaacgc tgctgattat ctcctacaac tgtttgataa taaacttcga tacctagatc
     4321 agctagctgt tctgacaaga aagtggcatt cgtattcacg acttgtccta gtaaaagttc
     4381 tgttccgaca gctattattt ctgctttcat tacttcccgc tcccttatat agtatacgct
     4441 gtatttttat atttttttat t
//
LOCUS       DAYNVV010000118         4430 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.123, whole genome shotgun sequence.
ACCESSION   DAYNVV010000118 DAYNVV010000000
VERSION     DAYNVV010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.123"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(205..660)
                     /locus_tag="ACGXWR_002796"
     CDS             complement(205..660)
                     /locus_tag="ACGXWR_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LMxysn_1693 family intestinal colonization
                     protein"
                     /protein_id="HFK0804266.1"
                     /translation="MKKQLFKTFLLSTSILTFGSAITPSGAVFANENNISDIATYSDD
                     EYYYVLDEPVIQTRTWSKPQSWSIAKGSRTYLGIETHSRGTKLSVSANVFGMKIEIAR
                     NTSASGKFKKYRQNARITVTYRVYRKVDNKYIRTQTSTANTQYIDYIPA"
     gene            complement(1068..1238)
                     /locus_tag="ACGXWR_002797"
     CDS             complement(1068..1238)
                     /locus_tag="ACGXWR_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804267.1"
                     /translation="MTRKKLIFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNS
                     PNEELFVKETDK"
     gene            complement(1254..1724)
                     /locus_tag="ACGXWR_002798"
     CDS             complement(1254..1724)
                     /locus_tag="ACGXWR_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFK0804268.1"
                     /translation="MTDKSIKEFAEELGVSKQAIRKYFDKLPTKLTPKLIGGKYVISA
                     KAQEFIKNSINQINEVDTEVDSLVDSILIAELKEKNKQIDHLQGVIEIQQKLLDQQQQ
                     LTLQANQQIDKLQKRLQLVYTEETSENESTTLSEETESIEKQTKKKQKWWKLWK"
     gene            complement(1734..2702)
                     /locus_tag="ACGXWR_002799"
     CDS             complement(1734..2702)
                     /locus_tag="ACGXWR_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFK0804269.1"
                     /translation="MSNEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYNQGTIDQRVFNPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEEQNRALELANRQTQHEKETTSLQERIKEQKRKLELL
                     QQLEELEKQQKNRENETDKQKLDNNSDIPLELRKDLLDNLQNLFKD"
     gene            complement(3883..4047)
                     /locus_tag="ACGXWR_002800"
     CDS             complement(3883..4047)
                     /locus_tag="ACGXWR_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804270.1"
                     /translation="MKLTKLTISLVIIAGIILYFVLPANQFFLYFGIPTILIVNGVRI
                     FEQRKKCSST"
     gene            complement(4066..>4430)
                     /locus_tag="ACGXWR_002801"
     CDS             complement(4066..>4430)
                     /locus_tag="ACGXWR_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HFK0804271.1"
                     /translation="FSVLFLINILNTSFSEGINPNEVNGSLLLFFLNAATYGAFLEEG
                     IFRFCMIDPQANKKQQYISILISSFLFSIVHGGGLSIFFIGIILSFVYIQTKNIWYSI
                     VAHGFYNTIGILIYLISI"
BASE COUNT         1371 a          737 c          707 g         1615 t
ORIGIN      
        1 aaaaaaaact atatttaaag agttttttta gatttacttc tttgaattca cgaatgaagg
       61 tagaatgaaa tagtataatt attagcacta aaaaaaatat atcactatgt tcaaataaaa
      121 aatatatatt tgacggtact cctaatgatg ggatagcaaa ggtcaaaacc aagtaagcaa
      181 tactaattat ccattttatt gtcattaggc aggaatataa tcaatatatt gtgtatttgc
      241 tgtagaagtt tgagtacgaa tatatttatt atctacctta cgataaactc tgtaggttac
      301 agttattctt gcattttgac gatatttttt aaattttcca cttgcagaag tgtttctggc
      361 tatttcgatt ttcatcccaa atacatttgc actgacagat aactttgtac ctcgactatg
      421 agtttctata cctaaataag tacggcttcc tttagcaatt gaccagcttt gaggtttaga
      481 ccaagtcctt gtttgaataa ctggttcgtc taacacatag tagtactcat catcagaata
      541 agtggctata tcagaaatgt tgttctcatt agcgaatacc gctccgctag gagtaatagc
      601 agaaccaaaa gttaaaatag aagtagataa taaaaaggtt ttaaataact gttttttcat
      661 caaaatcacc tcgaatataa gatacttaag aaaacgcttt ctttatataa ttagaataat
      721 caggaaattt aatgttgtca agagggttta ttttataaaa gctgttatat taaaggttag
      781 tagacataat gtcgactatg ccaagtagcc cttgtatcaa ccgatacaga ggctcacttt
      841 gtgattttgg attggtctag gtaaaaagct ctttttaagg cttgattttt cgcggttatc
      901 tatatctaat tctttgtgca tttttatctg tcatttttta aagacttgtt atttttgaga
      961 ggatttgata cgctttgttt gtatctcatt ttcatctaat aaatggttta tgttgctaaa
     1021 ctaggataat ctcattttgg gctgctcgtt agagcagtct ttttttatta tttatccgtt
     1081 tcttttacaa ataactcttc gttaggactg ttgtaataat ttggattcaa tttcaattca
     1141 ccatgtttat ttcctttatt gatcactgac aataacatcg gactgaagcc tagaattcct
     1201 agtaaaatag aaccaaatat gagctttttt cttgtcatga atgtttcctc cagttatttc
     1261 catagtttcc accatttttg cttcttcttt gtttgttttt ctatcgattc tgtttcttca
     1321 gaaagagtag ttgattcatt ttctgaagtt tcttccgtat aaactaattg taaccgtttt
     1381 tgtagtttgt cgatttgttg atttgcctgc aaggtgagtt gttgttgctg gtcgagtaat
     1441 ttttgttgta tttctatgac cccttgtaaa tgatcaattt gtttgttttt ttcttttaat
     1501 tctgcaatta aaatactatc aactaaactg tcaacttcag tatcaacttc atttatttgg
     1561 ttgatactat tttttataaa ctcttgagct tttgctgata ttacgtattt tccacctatc
     1621 aacttaggtg tcaacttggt tggcagttta tcaaaatact ttctaatggc ttgtttgctg
     1681 acacctagtt cttctgcaaa ttcttttatt gatttatctg tcatgaatac tccttagtct
     1741 ttaaataagt tttgaagatt atcaagtaag tcttttctta gttctagagg aatatcggaa
     1801 ttgttgtcta acttttgttt atccgtttcg ttttctctat ttttttgttg tttttctaac
     1861 tcttctaact gttgtaaaag ttctaatttt cgcttttgtt ccttaattct ttcttgtaat
     1921 gaagtagttt ctttttcgtg ttgagtttgt cgattagcta gttctaaagc ccgattttgt
     1981 tcttctttgg ttggtgcatg tttgttaaag tcgtctgctt ttttgatttc tggtttaaat
     2041 gtgaattggt agccaatgac aggcttccca cggccttttc cgtatttctt tttgattgtt
     2101 aaacctttaa agattgcggt tagttcttgt cgtattggat tgaacacacg ttgatcgatc
     2161 gtaccttggt tgtaactttt aggaatatca agtaattcat gaaagtcttc ttttgaaaaa
     2221 taagcgaaac ctttggttct gtattgtttt agtaatcgaa acattgtttt tgaataactg
     2281 ctttctaatt cattgaattg ttggagagaa tagcgcaccc attcttcaag attattaagt
     2341 aagggtaagg ctttttcatg aacttgtatt tcagcaaaag gaatatcagc ttttccgtcg
     2401 attttaaatt gattaaataa aacaaaacgt tcacgttgca aaccgtcagc acttcttcta
     2461 ccaaaacgta aatccattaa tttgtcatac gttgtttcta aatcatctat gaatcgaaca
     2521 tttgcagttg ctttataatt gcttaaatct tttaattgct cgaatgtaaa ttgtactttt
     2581 ttatcaccta catcacgcat tcttgatacg atagagaaga acaaattcat ttcgactggt
     2641 gtaaattttc gcaacggaat tgtatttaat tcatgatgat actttacgat ttcattagac
     2701 atatttaaaa tagctccttt cttactcgca caagagatac agacgttatg aaatacaaaa
     2761 tgtctgttta tctacatctt atattaacat cgtcgatgta ctaattcaat gtacaaacag
     2821 acaaaacgat gtagataaac agacaaaacg atgtagataa acagacaaaa cgatgtagat
     2881 aaacagacaa aacgatgtag ataaacagac aaaacgatgt agataaaagc gtcattccct
     2941 tgggagagta aggatacagc cgacggtaaa gaggtttaaa aagaggttta aaaagagatt
     3001 ataaaagagg gggacaaaat ttcccgccta aaaaaccact tcttttttct ccaaacagat
     3061 tcgcgcattt ttctaaactg ggaatcttac tccctatagt tgcttaaaaa ggtgtgatcg
     3121 ctctgctctc acattatact gcgcagtcgc ctccggctcc tttgctaaaa ctgttcataa
     3181 ggaactcttt gagaagctat gagccttcgt ttgagacgtt ttaagacagt cttagtataa
     3241 atcccttatc ttgttcttaa agcgccttac aggcggtcag ggcaagccct aacaacccta
     3301 aaattgtctg aattccctct aaaattcgat ttaagcactc ttaactctat tcttatatat
     3361 ttatatactt agacatttga aacgccttaa aacgcaaatt agagcttgat aaagatattt
     3421 gctcgtgtgc ctagactttt aaaaaagtcg gcacacgcca tgacaaagct gaaataaact
     3481 gtttcagctt tgtcatggcg gattcgctca cttgaaaaag tgttcatttc gctcgattat
     3541 tagcatatat tttttcgctt ttttgctagc caaattttgc attagttcgc tcataagtcc
     3601 caccctttca gtacgtccga gggacgtatc gttcgtaatg tgagagtgcc tataaggtca
     3661 ctctctacaa aactcactaa aagggtttgg caagctctat atttgctagc caaataccta
     3721 cgtatttggt gcaaataacc gcttgtcaaa ggggcgcaag ctcccccttg aatcccccct
     3781 caaaacccac gctccacaat acaaaaaagg ctagcaaatg ctagccactt tttgtaaagt
     3841 ttcgcttgtt tcaccttcgg tgaaattgtt gctttgcaac gatcaggtag agctacattt
     3901 ttttcgttgt tcaaatattc ttacgccatt tactattaaa atcgtaggta ttccaaagta
     3961 aagaaaaaat tgattagcag gtaatacaaa atataaaata ataccagcaa taattaccaa
     4021 acttatagta agttttgtta atttcataaa gtatgccacc ttatcttata tagatatcaa
     4081 atagattaat atgccgattg tattataaaa tccatgagca actatggaat accatatatt
     4141 ttttgtttgt atataaacaa aacttaaaat aataccaata aagaaaatac ttaggcctcc
     4201 cccatgaaca atagaaaaca gaaaagaaga aattagtatt gaaatatatt gttgtttttt
     4261 gtttgcttga ggatcaatca tacaaaatcg aaaaattcct tcttctaaaa aagctccata
     4321 agtagcagca tttaaaaaga ataaaaggag agaaccattt acttcattag gatttatacc
     4381 ttctgaaaaa gatgtattta gaatattgat taggaataaa acagagaatg
//
LOCUS       DAYNVV010000119         4424 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.124, whole genome shotgun sequence.
ACCESSION   DAYNVV010000119 DAYNVV010000000
VERSION     DAYNVV010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.124"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            690..1658
                     /locus_tag="ACGXWR_002802"
     CDS             690..1658
                     /locus_tag="ACGXWR_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFK0804272.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADVRNHDLDVRRYMGKVEY"
     gene            1669..2484
                     /locus_tag="ACGXWR_002803"
     CDS             1669..2484
                     /locus_tag="ACGXWR_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HFK0804273.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKEIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            2552..3262
                     /locus_tag="ACGXWR_002804"
     CDS             2552..3262
                     /locus_tag="ACGXWR_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFK0804274.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYIMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            3298..>4424
                     /locus_tag="ACGXWR_002805"
     CDS             3298..>4424
                     /locus_tag="ACGXWR_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFK0804275.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIK"
BASE COUNT         1490 a          661 c          921 g         1352 t
ORIGIN      
        1 atacaaataa ttcaccaaaa aggtgagtaa tgccattttt gaaaattgag cttgttttat
       61 gtctacatct gtatccgtat ataatccaaa ggattataaa ctcagaagag tctttatttt
      121 ttctgaatat aactactgta tcaaaaacaa tcgattatga gacaaaacaa aatgacctct
      181 tttatttaag aaaggaggtc attttttgta tcataaattg tattaaaatc aatgtatcac
      241 tttttaatca gttttaagac cataaattgc gtactaaaag aaattctgca attcaaaata
      301 aagcatttta agccattttc aaatttaagt gcacccatct acccgtcaaa tcactttatt
      361 ttccactcca gtagtttcct aattcaactg tgtgcaaaaa cgatttcttc taaacaaatc
      421 aagacaaact tataaacctt catcccagca ccataattat ttaaatcata ggcatttttc
      481 gaaattagta tatgtactca agtttcactg cagattattt atatttttta gagaaataaa
      541 tttttcctat tgacaaacac aaagaaagcg gatacaatgc aattatgtca catgacgtta
      601 tatgacgtta tgtgatatct ttacatttaa tcagttactt ttattttgga taaaattaac
      661 atttttaaaa ttttaaggag gaaatgttga tggatgtagc aaaaacggtt aacgcaattg
      721 tagaaaaaaa tgatggagag atttctggaa tttatttggt ggcttgtggc ggttcgctgg
      781 tagatatgta tgtctcagat tattttctta aagccgaagc atcgaagtgt attacaggct
      841 tatatacagc gaacgaattt aaccatgtaa ccccaaagca attagatgat aaatctgttg
      901 tcattctatg ttctcatgga ggaaatacag cagaaacggt aaaagcagga gaagtcgctc
      961 aagctagagg agctgtgact gttggtctga ctcataataa aactgcggat ttattaaagg
     1021 tttctgatca tagtttcctt tacgaatggg gagatgatgc aaaaatagtc aataatccta
     1081 tggccatcat tcttgattta actgtatctt tggtcaatgt taccgaaaca tttgaacatt
     1141 acggtaaatt cagagaaggc atgaaggtta tcgataccgt aattgaaaat ggcattaagc
     1201 aggtgcagga tcgtattaaa gtgtttgctg ataagtacaa agatgaaaca atgttttata
     1261 tcttaggtag tggaccatca tatggacatg cttatggttt ttcaatttgc tctttgatgg
     1321 aaatgcaatg gcttgattca acttctgttc attctggaga attcttccat ggaccttttg
     1381 aagtaacaga caaagatacg aattttattc tcttgatgag cattggacgc actcgtgctt
     1441 tagatgaacg ggcaaaacga ttccttgata aatatgcaga aagagtagaa atcgttgatg
     1501 caaaggaact aggattggat atgatatcag atgaagtttc tgaattcttc aatcccattt
     1561 tattctacag tattctttca gaatatcgtt cagctttagc agatgtacgc aatcatgatt
     1621 tagatgttcg tcgctatatg gggaaagtgg agtactagga ggattaaaat gaaggtatta
     1681 ggcttaggtg ataacgtcgt cgataaatat gaaaatctgg gaattatgta tcctggagga
     1741 aattcattga attttgcagt ttttgcaaaa aaactgggac atgaaagtag ctttatggga
     1801 gtttttggct cagatgagga ggcagctcat gttttatcag caataaaaga aataggactg
     1861 gacaacagtc actctcgctt tgaaaaaggc gagaatggct gtgccagagt gaagattgat
     1921 gagggcgacc ggattttcct tggcagcaat tcgggaggtg ttactcgtga atacccgatt
     1981 cagcttactg aagaagacag agaatattta aaccagtttg aattgattca tatgggatta
     2041 tatagccatg tcaatcatct attagaagag ttacaaaatg tttctggaaa gatttcttat
     2101 gatttttctg acgactttac ggaagaagag gttcagcggg caattgataa agttgatttt
     2161 ggcttctttt ctatagaaga cttttccgat gaagaagtaa agcagttttt gatgaagcat
     2221 ttttgtgagc gaaatgatgt attgattgca acccgaggag aaaaaacggc tattggttat
     2281 gatggagcaa agttttatga agtgaacccc gtgctagaag aaccagttga tacaatggca
     2341 gcgggagatt ctttcttaac agctttccta ctttattttc tcgaagggga cgatatagtc
     2401 accgcgatga aaaaggggaa tgaatttgct gggaagtctt gtctggttga cggttcgttc
     2461 ggctttggta ttcattacga ttgagcttgt tttaaattcc tgcatttgat aacctaaaga
     2521 aagaaatccc ggtaaagtgg aggttaaaaa aatgctggat acaaatgcac aattaccatt
     2581 gtacttacaa ttaaaagaaa tattaaaaaa taaaatcaat acaggggagt atcccgagaa
     2641 tacgaaaatt cccgctgaat cagagctgat agaaagttat gaggtcagcc gaatcacagt
     2701 gagaaaagca gtagaagaac tggtagaaga agggtaccta cttaaaaaac aagggaaagg
     2761 aacttttgtc aaccggcata aagtttttcg taaaattgaa tatattatgg gtttcagtga
     2821 gagttgtaaa tctaatggtt ttacaccgac tagcattgtt ttggaacgca agatcattcc
     2881 agcaactgaa gggatggcaa aaaaactcga tatcgctcaa ggtgatgatg ttttatatat
     2941 ccagagaaag cgaatggcgg ataacatccc cattatgtta gaaaacaatt atttttctta
     3001 tgaaagatat agtttcttaa tggaggaaga gctgactgat tctttgtatg aagtacttaa
     3061 agtccaaggt accttagcca tcaatcctgg ggaaactgca cttgaaattg tcacagctga
     3121 tgaccaaatt gccaaaataa tggaagtagc tgttgggacg ccctttttct ttatggatac
     3181 tttaatcaac gatcaaaaca acataccaat tcatgtaggt aatcaatatt acctgggaga
     3241 agtatatcgt ttttacttat gatttcctgt ttggatttca aggagtagat tttatttatg
     3301 aagcaaatat tgcggtcaaa aatgattttt gatggagagc agccaccttt caaaggttat
     3361 attgtaatca atgaagggat cattgaaaag gtggaaaaca actggaatta cagtgatcta
     3421 ttaaatgaaa acacggaatt aattgcttat gatgatcaat tcgttatgcc agcaattcat
     3481 gataatcatg tatttttcag tggttatttg gctatgaatg ctggcataga tttaagcgat
     3541 acatcttcag ctaacgaggc tgtagagcgt attaaagctg taatgaacca taaaaaagca
     3601 gatgaaccaa tttatgctca tggctgggat gctgccctgt ggaaaactga cccatcagaa
     3661 gagctattga atgaaataaa ccactttggt ccaatcacag cgatcgacaa aaatcgcagc
     3721 cattgttgga tgaatgctat tgctaagcag acttatggtt ttacagaaaa agaaaccagt
     3781 gctgaaagtc gagtattatt aattaaggaa atgctagcaa acaaaaagct tttagcagag
     3841 gtttacgctg aatttgaagc attactgctt tcaaaaggtg ttatatcaat gaaagaaatc
     3901 gtttttgatg acgcagaatt tctttctaat atacctcaga ggaaaatact tagtaaccta
     3961 tatgtgcagg cagtccaaga acctctacag catgaacttc tatatgagta taaggaaaaa
     4021 gttttccctg aaaaggtccg ctttggtgga gtgaagatca tggtagatgg tgttgttgcg
     4081 gatagaagtg gagatattta cggtgtttat cagtcaggag tagcttcacc cgagattgac
     4141 tatgaggcaa ttaaagcaga agttgctgca ttcaatgaag tagagattcc ttgctgtttg
     4201 acaacggaag gagataaagc gggttataaa gctgcgtcaa ttcttgtcga atttggaaag
     4261 cggttacctg aaggcgtttt taattcgatt agtgatttgg aaatggttac tcaaaagaca
     4321 gcagaaaaaa tgaacgaagg acaagtagta gcagaggtat atccacaaat tctcggcttg
     4381 aatcaaacgt tagaagaggc ttacatgtca actgttataa aaaa
//
LOCUS       DAYNVV010000120         4386 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.125, whole genome shotgun sequence.
ACCESSION   DAYNVV010000120 DAYNVV010000000
VERSION     DAYNVV010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4386
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.125"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(1..355)
                     /locus_tag="ACGXWR_002806"
                     /pseudo
     CDS             complement(1..355)
                     /locus_tag="ACGXWR_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            425..586
                     /locus_tag="ACGXWR_002807"
     CDS             425..586
                     /locus_tag="ACGXWR_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFK0804276.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            605..1882
                     /locus_tag="ACGXWR_002808"
     CDS             605..1882
                     /locus_tag="ACGXWR_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0804277.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1892..2548
                     /locus_tag="ACGXWR_002809"
     CDS             1892..2548
                     /locus_tag="ACGXWR_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0804278.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2548..3924
                     /locus_tag="ACGXWR_002810"
     CDS             2548..3924
                     /locus_tag="ACGXWR_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0804279.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            4054..>4386
                     /locus_tag="ACGXWR_002811"
     CDS             4054..>4386
                     /locus_tag="ACGXWR_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFK0804280.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT         1690 a          504 c          776 g         1416 t
ORIGIN      
        1 tgacgagaaa tatttagaat tttgcacatc gctgatatgg aatatttatg cttgttggca
       61 tcaattactt gtcttttcgt ccgaatatca gcgccgcttg ctttaaaata tcattctcca
      121 tttcgagttg cttatttttc tttcttagtg cgatcaattc tgcttgttct ggtgttaagt
      181 tgtctctttc tttgaatgag cccgttgatt gtgcttgctt catccattta tcgaaagaag
      241 aaggcgtaag ctcatactct cgaataattt ctgcgcgagg cttaccagcg agatagagat
      301 cgacgatttg ttgtttgaat tcttttgaat aggttcttcg ttgacgtctt ggcatgaaaa
      361 atcctccagt gtgtttttta ttattctaca caccttattt tttctgtcta gtctagtgta
      421 gccgattcag gataaggata agtgtattaa ttgtggaaaa tgtaaaaaag tttgccaaat
      481 gaataaagat tcagttgaga attgcaatca tctggagtgt atcagatgtg gacgatgtaa
      541 aaatgcttgt ccagtggatg caattagtta tggagtaaga aaatagagag gagtagttag
      601 gaaagtgata aaaaatgcta tagcatatat tacaagaaag aaaaatagaa ctttaataat
      661 ttttatcata ttaactatag ttctttcttg cttgtattct tgtttaacaa taatgaaatc
      721 aagcaatgaa atagaaaagg ctttatatga aagttctaat tcttcaatat caataacaaa
      781 aaaagatggt aaatatttta atgttaatca atttaaagat attgaaaaat taaaagaaat
      841 tgaagaaaaa ataattcaat atgatggatt agcaaaacta aaagatgcta aagtagttag
      901 cggagaacaa agaataaata gagaagattt atctgacgaa tttaagaatg ttgtttcact
      961 cgaagctaca aataatacta aaagaaatat tttatttagt agtggagtat ttacaattaa
     1021 agaaggtaaa aatatagaag aaaatgataa gaattcaatt attgttcatg aagaatttgc
     1081 taaacaaaac aatctaaaat taggtgatga agttgatctt gaattactag atattgaaaa
     1141 aagtggaaaa ataaaaagtc ataaatttaa aattataggg atcttttctg gtaaaaaaca
     1201 ggaaacatat acaggattat cttctgattt tagtgaaaat atggtgtttg tagattattc
     1261 aacaagccaa gagatattaa ataattcaga aaataatgaa attgcaaata aaattttaat
     1321 gtattctggt agtgcagaat ctacagactt agccttaaac aaattgaaag agcttaaaat
     1381 tgatgagtca aagtattttg ttgaaaaaga ttctaatgcg tttgaagagt ctttagagtc
     1441 agtgagtgga ataaaatata taataaaagt aatgacttat tctattatgt taggtgggat
     1501 ggttgttctt tcattaatct tgattctatg gttaagggaa agaatttatg aaataggtat
     1561 attcttatct attggaacat ctaagataca aattataatg caatttatat tcgagttaat
     1621 attcatatcg ataccaagta taatatcttc cttattttta ggaaatgtat tactaaaagt
     1681 aattgtagat ggattcatta actcagagga ttcaatgatt tccggtggaa gtttaataaa
     1741 taatagtagt tttatgtcaa atataacaac acttggacaa agttatttaa tattaataag
     1801 tattattgtt ttatcagttg tatttgcttc ttcattaatg ttaatcaaga agcctaaaga
     1861 aatcttatca aaaataagtt aggagaaaat aatggatata ttagaaataa agaatgtagc
     1921 atatagttat gcaaattcta aagaaaaagt tttgtcagga gtaaatcaaa aatttgaact
     1981 tgggaagttt tatgcgatag taggaaagtc aggaacagga aaatctacac ttctttcctt
     2041 acttgctgga cttgataaac ctcaaacagg aaaaatattg tttaagaatg aagatataca
     2101 aaataaagga tatagtaatc atagaaaaaa taatatatct ttagtatttc aaaactataa
     2161 tttaatagat tatttatcac caattgaaaa tattagatta gtaaataaat cagcagatga
     2221 aagtatcttg tttgaactag gtttagataa aaaacaaata aaaagaaatg ttatgaaatt
     2281 atctggtgga cagcaacaaa gagtagctat tgctagagca ttggtatcag atgctccaat
     2341 aatactagct gatgagccta ctggtaatct agacagtgtt actgctggag aaataattaa
     2401 tatattaaag acattagcta aagatagaaa taaatgtgta atagttgtaa cacatagtaa
     2461 ggaagtagca gattctgcgg atatcatttt agaactaagt ggtaaaaagt tgaaaaaagt
     2521 aaataaaatg aatttggagg ttgaataatg ataaaaaatg catttgctta tgtaactaga
     2581 aaaagtttaa aatcattaat tatcatatta gttattttat ctatgtcaac tttaagtctc
     2641 attagtttat ctattaaaga tgctacggac agagcttcaa aagaaacatt tgctaatata
     2701 acaaatagtt tttctatgga gataaataga caagtaaatc caggaacacc tagaggtggg
     2761 ggaaatgtaa aaggtgaaga tattaaaaag atatctcaaa cagatagtat agactcctat
     2821 gtaaaaagaa taaacagtgt tgcagattta gttgattatg atattattga aactcaagag
     2881 actcttgcga atcaatcacc tgaaagagca aagaatttta aaagaacagt tatgttaact
     2941 ggggttaacg actcaacaaa agaaacaaaa tttgtatcag aagcatataa attagtagaa
     3001 ggaaagcatt tagaaaatga agataaaaat aaaatcttaa tgcataaaga tttagctgaa
     3061 aaaaataacc ttaaagttgg agataagata aaaataaaat ctaatttatt tgatgctgat
     3121 aatgagaaag gtgcagatga aacagtagaa gtagaaatta aaggtctatt cgatgggcat
     3181 aatagcggtg tagtaagtgc agcacaagaa ctatacgaaa atacattaat cactgatatt
     3241 catacagctg ctaaagttta tggtaatacc gaagatacag ctgtatacca agatgcaaca
     3301 ttctttgtaa aaggtgataa gaatcttgat agtgtaataa aagatcttgg gaaattagat
     3361 ataaattgga gagaatataa tttgattaaa agttcatcaa attaccctgc attacaacaa
     3421 tctatatcag gtatttactc aatttcaaat aaattatttt ttggctcatt aatatttgca
     3481 ggagttgtag tttcattatt attattctta tggatgaatg ctagaaagaa agaaatagca
     3541 gtattactat cattaggtat atcaaaatta gaaatttttg gtcaattcct aattgagatg
     3601 gtatttatat caatccccgc attcgttggt tcctatttct tagctcaata tacagctgac
     3661 aagcttggga ataatatatt gaataaggtt actggtgata tagctaaaca aatagctaaa
     3721 caatctgcat ctagccaatt aggtggtggg gcagaagctg aaggatttaa caagacatta
     3781 tcaagtttag atatcaatgt attacctaaa ttcatgattt atgtagttat atttatgagt
     3841 ttagtacttc ttgtatcatt gattatttct tcattcaata tattaagaag gaatccaaaa
     3901 gaattattaa ttgacaataa ttaaaatttt cggtgctttt tagcaccaaa aatgagagtg
     3961 taatataaac cgtgtaagta accatcaatc ctaggcgggt ggttgcttca cggtttttat
     4021 ttttctaaaa taagatcaag aggtgattac acgatggcta gaaagaaaag aaatcctgat
     4081 gctgagaagt tagctgaatc cattttgaat acttatcaac ccgaatctgt agaggatatg
     4141 caagatgttt taaaagatgt gtttggtccc ttatttgaaa aaatgcttca aggagaattg
     4201 aataaccatt tagggtatga cgcccattct aaagagccaa agaaacatga caatcgacga
     4261 aacggttatg gcaataagac gcttaaaacg agctttggta aagtaaacat tgatgttccc
     4321 agagaccggg aggcttcttt tgaacctgag ttgattccta atagaaaacg agatgtctcc
     4381 gacatc
//
LOCUS       DAYNVV010000121         4310 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.126, whole genome shotgun sequence.
ACCESSION   DAYNVV010000121 DAYNVV010000000
VERSION     DAYNVV010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4310
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.126"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(65..1285)
                     /locus_tag="ACGXWR_002812"
     CDS             complement(65..1285)
                     /locus_tag="ACGXWR_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFK0804281.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1305..1916)
                     /locus_tag="ACGXWR_002813"
     CDS             complement(1305..1916)
                     /locus_tag="ACGXWR_002813"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFK0804282.1"
                     /translation="MKMKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELP
                     LFNKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVD
                     KPVMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLID
                     EEQVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(1959..2891)
                     /locus_tag="ACGXWR_002814"
     CDS             complement(1959..2891)
                     /locus_tag="ACGXWR_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFK0804283.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLAELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
     gene            complement(3312..4172)
                     /locus_tag="ACGXWR_002815"
     CDS             complement(3312..4172)
                     /locus_tag="ACGXWR_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFK0804284.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
BASE COUNT         1230 a          866 c          707 g         1507 t
ORIGIN      
        1 agcttaaatc atagataccg taagggactt tattctttat ttaaaacttt gcaacagaac
       61 ctttttattt tacagaagca ctcgaaactg catctactgc agtttcatcg tgtgtgctgg
      121 cgctggttac tgcatctgtt tttccaccat gaacagatgc acttgaaacc gcatcttcat
      181 ttccaacaag ttgttgaccc gtttgttgta aataccactc aatgattggt ttgaaatcaa
      241 gaatgtattc attgattcca gcatactctc cattttcatc atgcattgct tggtaattat
      301 gcacaatata tttttctggc acttgttttg gtacatgaac acgtaccgca tctgttgctc
      361 cgcttcgcag ttgttgaatt acccactcta catttttata cgatttttct gggtgacagt
      421 tggctaatgg attccctacc tgaccgggca cacgagcagc taacatctct ttcgcttctt
      481 ggcgcaaatt ataatataaa aattggttat tattatctgc aaaagttaat tccatcggca
      541 tcgaatctaa aaagtaattg atttgatcca ctgtcaataa cccacgattt aatttgacgt
      601 aagtatttcc agaaacggca ccgactgctt cagaagcttt ttccaaccaa tgatcatctg
      661 acatatcaac atcgggtatt gtcgtagcaa ttgttcctgt cgcatgcaaa tcttctggtg
      721 gaagcttttt aggccctgct aaggtagaca cgactttaat gaattttaca aaacttgcta
      781 atgtactgcc taaaaagtca acagttcgtg gatcaatcaa gcgatcttct tggtcaaatg
      841 cttcttttgc ttttcccaat aaaaattcat ttccgggcat cactaatgca ttcacgcctg
      901 gtgcgtccaa aatttggcgc aagtgtaatt gcgcgcgtga agttccttga tcgtagtaag
      961 aagcacccac aaccattaca ggtttatttt caagtggatg gattttaaat gatagccatt
     1021 caagtgcact tttcaatcct gctggaaccg tatgattgtg ttctggcgta gcaataatta
     1081 ccccatcagc cattaagatt ttgcgattta gctgttgaat agcaggacta tttgtttgat
     1141 catcatcttg attgaacaga ggtaaatctt tgatttcaat gatttctaaa ttaaatagtt
     1201 catgatattg tttttggata aatgttaata atttacggtt atatgaaagt tcagctgctg
     1261 atccgacgat acctattaat ttcatctttg tttgctcccc tcgattaaat cgtttcccat
     1321 gaaaagcttt cggcttcacg tttatttgct tggtgcgcat gttgcaattg actagtgatt
     1381 gtgacaaaga gtaagaaatc tttgaatagt tcacgtaatt ttgcgacttg ttcttcatca
     1441 atgagtcgtc cttgctcatc aaaggcttgg agtgaatgac ccaataaaaa ttctgagctt
     1501 ggcataattc gtgcctttaa ctctggtgaa tccaatattt ggcgcaaatg tgcttgtgcg
     1561 cgtgaagaac ctaacgtgcc ataagacgct ccggtaatca tcactggttt atccacaaac
     1621 ggaaaaatac catatgaaag ccaatttaat gcgttaatca atgaagcagg aaccgcatgg
     1681 tcatactctg gtgtgctgat gattacgcca tctgcttgtt caatttttcc agcaatttct
     1741 ttaacaacat ttggtagttc tgtgttttca ggtttgttaa atagtggcag ctccttgatt
     1801 tcgacaattt cgatttctgc ctcatttaca aaataatttt tcataaactg taataattca
     1861 cggtttgttg accgcgttga atttgttcct actaatccaa taaatttcat cttcattctc
     1921 tttcctttct aacatcgatt tctgactgtt cgcacgtact aaattttttc aaatcctttt
     1981 gtatacaaga attgattctc ttttgttaca actgctccct cgatacccgg ctgttcttca
     2041 agcgctttca acacttctaa agaagatgct ccaaataaac gtgtagtcca gatttctcca
     2101 tctacagaag aatcagacaa aatcgtcagg cttgctacgt catttttaac tggaaagcca
     2161 gttttcggat caatgatgtg atgatacact gacgaaccat tttgtagata acgttcgtag
     2221 attccagagg taactaaaga ttggttgttt agtttaacca ccgcaagcga ctcttcacgt
     2281 gaacctttag gatttcgcaa accaatacgc caagcaccat ccgaacgtct tggtgattca
     2341 ccaaaaacaa cgatatttcc tcctaagtta actaaagcaa acgctgcatt tcgctctcgg
     2401 caatgtgtaa ttaatttatc tgcaatgtaa ccttttgcta acgcccccaa gtcaatcatc
     2461 attcctggtt tggttaaaaa aacggttttc attttttcat ctaattgaat ttggtgtgga
     2521 tccgttagca gaagtaactc agttatctct gcttttgttg gaaccaatgc atcttcaaat
     2581 ccaatgtgcc atttttgtac aaccggacca atagcaatat tcagataact atttcttgca
     2641 caactatgtg cttttcctaa tttgatgagc tcaaaaagtt caggatgtac aatcacagct
     2701 tgtcgtccag cagcttgatt gatggccatt aattcagaag ttgcatcatg tgcgctgaag
     2761 cgatgttcat aaacgtgcaa ccattcgcct aactctgcta gtaatcgact aggctcttca
     2821 tgcccaactt gtaatgtaat tgttgtcccc atcatttgcc agattttcgt ttcttcgatc
     2881 acctgattca ttttgtacct tctttacttg aactacggat tacatgagta attagttttt
     2941 atttttgtta ctgttttcac aaccagatga tacgcctgct agatttattt gtcaaccgat
     3001 tttatatatt tttttatata ataaggtaat tttaatataa aattttatat tgtaaaaaaa
     3061 caaataaggg aaacaaacaa cacatttttg tgtgttgctt atttccctct aactatcgtt
     3121 ttctatttga tggttaacct acttaaaata aatactgcaa cgacaaacgg agatcaagca
     3181 tgctttgtaa cgtattttac gataattacg actttatttt attactctat cttgctgcca
     3241 tacccgtcta tccctaatca tctttggtga attttttcaa agttagcata acaaaaataa
     3301 gtattttttc cttagttaat caatagtatc atttttttca tatgatttaa ttcatcaatt
     3361 aattttttgt ttttattaat tttagcaaaa gctagtgcat cttgaatcaa ttcgagcact
     3421 tctgccttcg acttattttt agcctgtgcg ttcttcgcta attgggcagc agctcgtgct
     3481 aagtaataag tcaaatggtt atccgaacaa atatcgattg cgtaatttag tagtgcatca
     3541 cttgtttcca aatcaccgtc ttgcgcaaaa aaaacaccac aatgaaagac gatatttaac
     3601 acccgccaga tatcttctgt tgtacgaatc ggatacgtat aaattttttc aaacactcga
     3661 ttgaaataaa cttctgcttt ttccaactct ttttctctag catagaccat tccaatacct
     3721 gtatatgcca ataaacgaaa caacgtgttg gctgtttctg ccatcaacaa ctgatcaaaa
     3781 tggaacaaca catccgtaat tggtgcattc gtaaaaatca tttcaaatcc ttttagatag
     3841 tagtaacgtg caatcagctc agactcgtca attaccttgg gatcaatggc tgctaaaatc
     3901 tgtgtcaatt gttcatattc actcgtaatc agtgaaaact ctgctttttc tagctgttca
     3961 tcaagttgtg tattgatcac gttcatcgaa gaaaaaagtt caactaacgg aagattgatt
     4021 cgattacata atttgattaa aatttttaac gaagggactt gaccattgtt ctcaaattta
     4081 cttaatgttg cttgtgtaca aattccttca gacacttctt tttgagataa gttggcagcc
     4141 tttcttgccg taataaattt ttcaatgttc attattttct ctccaatcag acctcacacg
     4201 aaaatcattt ctgtctcgat tttagcatgt tttctttggg aatgctttag gttctgttgc
     4261 aaagttttaa ataaagaata aagtccctta cggtatctat gatttaagct
//
LOCUS       DAYNVV010000122         4092 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.127, whole genome shotgun sequence.
ACCESSION   DAYNVV010000122 DAYNVV010000000
VERSION     DAYNVV010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4092
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.127"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..153)
                     /locus_tag="ACGXWR_002816"
     CDS             complement(<1..153)
                     /locus_tag="ACGXWR_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFK0804285.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWV"
     gene            complement(475..696)
                     /locus_tag="ACGXWR_002817"
     CDS             complement(475..696)
                     /locus_tag="ACGXWR_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804286.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(794..1039)
                     /locus_tag="ACGXWR_002818"
     CDS             complement(794..1039)
                     /locus_tag="ACGXWR_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804287.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            1279..1893
                     /locus_tag="ACGXWR_002819"
                     /pseudo
     CDS             1279..1893
                     /locus_tag="ACGXWR_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(2263..3264)
                     /locus_tag="ACGXWR_002820"
     CDS             complement(2263..3264)
                     /locus_tag="ACGXWR_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HFK0804288.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYFLKNEKKISVIMEKYKAPIQADPFSNLDESDLPF"
     gene            complement(3423..3689)
                     /locus_tag="ACGXWR_002821"
     CDS             complement(3423..3689)
                     /locus_tag="ACGXWR_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFK0804289.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            complement(3679..4035)
                     /locus_tag="ACGXWR_002822"
     CDS             complement(3679..4035)
                     /locus_tag="ACGXWR_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFK0804290.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
BASE COUNT         1295 a          744 c          542 g         1511 t
ORIGIN      
        1 tacccaacga taaatcgtag tatgacaaac atttattcca cgatcatata acaattcctg
       61 aacttcacga tagcttagat tgtaacgcag gtagtaacca acagcgacaa taatgacgtc
      121 ttttttgaat tgtttgcctt taaaatgatt cattactctg tcctctctgt cttttttctc
      181 aattttacac taaaatagat tttttggaaa actttgcaac agaaccgttt ttactatata
      241 cttcttccca gaacttgtcc gtctccttca aattatctct acctctcgag ttcattgggt
      301 ggtttgccca tttattaaac atggaatcac ctttctcata ctcatatatt tatgtcctat
      361 ttcaattata tttatatatg cttaaataaa tttgtatcct gaaatttatt gtaatatgaa
      421 gctgtatttt acatatagta accaaagagt taataaaata aaaagagcga accattatag
      481 atcagctctt ttttcattgc tgtttttaat cttatctaga atcacttcaa atgtttcaaa
      541 ggtatttaca tctaactgac ataaccaaag caagtacttc ttttctttgt aagtccaatc
      601 aatattacgg taagaggaca ttagattatg gtaccttgct ctttgttcaa ctgaagccaa
      661 ttcccagcgt ttttcaaata ttttttcttc ttccattatt gatccctcgc aagacgctac
      721 ctcaaactta aataatgggc agcgaaagtc taattcctta gatctaagta tagcaaacaa
      781 atatgaaaaa aacttagaag gtagtaaaag ttcttccgtc ttttgctttg cttctattct
      841 taatgtgttt cgttatcggt gccctacaaa gattttcatt aattacacac tcatttattg
      901 ttgtgtattt tctgacattt ctctcttgat caattatttt aattccatgg gcatcctgat
      961 agttcatagg agaggagcgg ctatcagaaa tagttgcacc tatctcttga acttctttta
     1021 caacttctgg aaaatccatc catcctgctt cagctgtcaa aagtaataat ctataatatt
     1081 tatctttcct tttcaatcta agaaatcgtc accccattct ttttcttcta ttataaacta
     1141 tttaactttt agaattcaaa aaccgtttgt ctatttagag tttaccctaa atagacaaaa
     1201 atataacatt gaaaaattta gagttctaac gtatgattag ggtgtattat aaacgttata
     1261 gaaaagtagg gaataaattt gaaaattgct tatattagag tttcatccat cgatcaaaat
     1321 gaacaacgtc aaattgaaga aatgaaaaag tttggcgctg aaaaaatttt tatcgaaaaa
     1381 caatctggag cgacgattag tcatcggccg attttccagg aagctttaga ttttgtcaga
     1441 gagcaagata tttttattgt agaagccatt gatcgacttg gacgcaatta tgacgagatt
     1501 atcgattcag tgaattatct aaagaagaag aatgtgcgac ttattatcac cagtttaccg
     1561 atcatggctg aagcaattgg aaatcctctc ctagataaat tcatcaaaga cttaatcatt
     1621 taaatctcag ccatgattgc tgaacaagaa cgtactgaat cgaaacgacg ccaggcacaa
     1681 ggaattaaaa tcgctaaagc aaacggcgtc tataaaggtc gtcctaagtt atacagtgca
     1741 gacaccaaag atcctcaacg tcgccttgtc tataggagta tcgttcagga tcttgagaat
     1801 ggggttgcta tctcaaagat tgcaacagac tacaatgtga ctaggcaaac aatttaccga
     1861 ataaaaaaag aaatcgacca actaattgta tgatttcttt tttgaatcac gtaattatta
     1921 attagctttg tcatcaatac agacaatcat tttagattca tctagctaag ttgattacat
     1981 ttatgttaaa aagaatttag ttaacataaa tataattgat gcataaatcg tccttattta
     2041 aaggcattta acattgacaa cttagtataa tgtatcttat gtaaactaat aagatttgaa
     2101 ttttatttta tacacactcg ataatagatc aattttatgg tcccccgcat ttacgattgc
     2161 acaagagaaa cataaagtcg acctattagc atttcttttc aattcaaaca ttaaaaaagt
     2221 ttatacctct gctactaaaa aatgaaatta tctatttaaa atttaaaacg gtaaatctga
     2281 ttcatccaaa ttggaaaatg gatcagcctg tattggagct ttgtatttct ccataataac
     2341 agatatcttt ttttcatttt ttaaaaaata ccttttaaat ttcttatagt cctctgaaat
     2401 caaaatatag cgtgatggat actcatcaaa agaagaatcg tattcttcct ttaaaattcc
     2461 cgatttactt aatttttcta gtacatcaaa tactctatca ctcaagtaac tccttaaatt
     2521 gttatcactt tcccattgaa ctacttttct ataagttgaa ttatcagttg aaaagataga
     2581 attttcatcc ataaacgcat atattagcag caatctttca tcattgtcaa attctattgg
     2641 atcaaaaata tctaagttgt catcaaaatc tttatcagtt ccggtaactt ttttgttaat
     2701 tactgaaggt gtcttgtaag aaatagaatc taaatcaaag cgttttgatt ctaaattatt
     2761 ttgtgctttc tcaattaaat aattcacttt ttttgtgaga aaccttctga tattgtcttt
     2821 gctatatgtt ccataaaaac ccttatcttc taaagagtcc ctgtacttct taacttctat
     2881 atactcttca gccaaaactt gtggaactgg ttcatctaag aaaaaaaccc ctacctcgcc
     2941 tttgctattt ttataaaagt aatcaatttc tgctatagtt cccgatctat aattatcaac
     3001 tggagaaccc aacttatggc caaaaatcgc taataatata tcactatttt ctacaatttg
     3061 tttattaata acactttgcc cagagctatt atttatataa gtaggaatcg cattcgtttc
     3121 ccatcgaatt ggcatcaaaa ttacttttgt attatctgta ttttctatat tccatctata
     3181 tatggtttct tctacttcat tcctctttgc tgctatatca cctggtgatg ctataaatac
     3241 ttttattaga tttatggttt tcatttattg tacctttctc tttatgtctc tttaaagtaa
     3301 tttttgtata aaatttattg acttttacac tataggacaa cttttatcta tttagtacaa
     3361 aaaggcccac taaactaatt gattagttag gagcctatta caggtatatt ttcaactcgc
     3421 ttttaagcaa attctactac cagctttttg cctaatgccc tagcgatatc atcaagttta
     3481 tcgaaagata cgttatcccc tctctcaatt cgagcaatag tagattgagt tgtatgtgct
     3541 ttttgtgcaa gctccgcttg agttaggcct gcttcctccc gtgcatgata aagagcaacc
     3601 gcagtttcga gttttcttcc ttcacggtca tatgcttctg caaaatcttt gtctttttgc
     3661 ttttcttcaa tcaatttttt aatcatcatt tgtgaaccac tcctctctaa gttcttttgc
     3721 atgtttaagt tcacttattg gtgttttctc cgttttttta gtaaatccat gggtaatgac
     3781 ataccttcca ttgaccacat ggaaatagat agctctttgg atgtttgatc ctaccttact
     3841 tcttaattcg tacaaattag tgtctaattt tttcacccat ttcaaccgtt gagctactag
     3901 catcccattc ttttctgttt cttctattgt acgtaaaagc ttcgcactat ctttttttgg
     3961 taatgtttcc aaccattcta aaaattcatc atgaccatta ggtcttttaa atgtttcaaa
     4021 agatattttt tccataccca attatatcat atattgattt tatattatag tatataacat
     4081 aaaaattcga at
//
LOCUS       DAYNVV010000123         3971 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.128, whole genome shotgun sequence.
ACCESSION   DAYNVV010000123 DAYNVV010000000
VERSION     DAYNVV010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3971
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.128"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..1357
                     /gene="mobP2"
                     /locus_tag="ACGXWR_002823"
     CDS             <1..1357
                     /gene="mobP2"
                     /locus_tag="ACGXWR_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MobP2 family relaxase"
                     /protein_id="HFK0804291.1"
                     /translation="NEAQSLMEHGINFDKLEEQDFTKYLSYMTRHYALEQKKELTQRE
                     QKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEVKGSDLKEIKQIFQRGQQKGSI
                     IYQDVISHDNSYLEKMGLYDPKTDTLDEEGLKAAGRKMMETLFEKEQLNETGYWMATI
                     HRNTKHIHIHFAVVEKENTRKPYTEIENGVSYIVPKGKRRQATLDAMKTNYVHELERF
                     SYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYDRHAMNLLNEVYKTLPEKRSEW
                     NYGDENRTKLSPFTRGKLDELTKYVLTKEPGYQEYIQISKALKEEAKSLYGESKRETK
                     NAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVNQMQSIYNERSFRTLKQLPTNE
                     YKYSYQEFVKRRKQFQQRVVTQRSLRQLNRTINAHEEKYHASKAYEEQQRRIQMEQER
                     Q"
     gene            1369..1704
                     /locus_tag="ACGXWR_002824"
     CDS             1369..1704
                     /locus_tag="ACGXWR_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804292.1"
                     /translation="MKQYLDQWKVIEGSLKEERIEQLPDCLEKEHLFQISEMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEINEEGINNFPCESI
                     EESISLTEC"
     gene            1851..2045
                     /locus_tag="ACGXWR_002825"
     CDS             1851..2045
                     /locus_tag="ACGXWR_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804293.1"
                     /translation="MTQTTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQNGNI
                     LTLNLTTKMFVDAVENYPFV"
     gene            2077..>3971
                     /locus_tag="ACGXWR_002826"
     CDS             2077..>3971
                     /locus_tag="ACGXWR_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArdC-like ssDNA-binding domain-containing
                     protein"
                     /protein_id="HFK0804294.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNNQFQKLFDHQKLTNGQ
                     PMNDKRNGRSWFNQQEKIENKIQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKEKDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSSEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTLEKAIPYI
                     AAWTKNG"
BASE COUNT         1603 a          622 c          826 g          920 t
ORIGIN      
        1 gaatgaagct caatcgttga tggaacatgg aatcaatttt gacaagttag aggaacaaga
       61 ttttaccaaa tatctttctt atatgacccg tcactatgcg ttagaacaaa agaaagaact
      121 gacgcaaagg gaacaaaaag aataccaacg gttgaaccaa gcaatgaaaa aatatcaaac
      181 agagccacat aaaaaagctt caggaaatct tcctggagtt ttttctatgg cttcagacga
      241 agtgaaagga agtgatctga aggagatcaa acaaatcttc caaagaggac aacaaaaagg
      301 ctcaatcatt tatcaagatg ttatctctca cgacaattcg tatcttgaaa aaatgggctt
      361 gtacgatccc aaaacagata ccttagatga agaaggtttg aaagcagctg gaagaaaaat
      421 gatggagaca ttattcgaga aagaacaatt gaatgaaaca ggttactgga tggcaacgat
      481 tcaccgtaac actaagcata tccatattca ttttgcagtt gttgaaaaag aaaatacgcg
      541 taaaccgtat actgagattg aaaatggtgt gagttatatc gtaccgaagg ggaagagaag
      601 acaagcaaca ttagacgcaa tgaaaaccaa ttatgtacat gagttagaac gtttctctta
      661 tgaaaaggat cgaatgatcg gtatggagaa acgaaattta ttgacacgaa aaagtgattt
      721 gcgtaacacc ttaacaaaag tagtaaaaga accagcacgt tacgatcgac acgccatgaa
      781 cttattaaat gaagtatata aaaccctacc tgaaaaacgt tcggaatgga attatggaga
      841 tgaaaatcga accaagcttt caccatttac aaggggaaaa cttgatgagt taaccaaata
      901 tgttttaaca aaagaacctg gatatcaaga atatatacag atttcaaaag cattgaaaga
      961 agaagccaaa agcctttatg gggaaagcaa aagagaaaca aagaatgcag aaaaaaacgc
     1021 cctctttgat ttaaaaaagc gcacaggaaa tgcgatttta acagaactga agagacagga
     1081 tagtcaaata aaaccattaa tagaaagtgt caatcagatg caatctattt acaatgaacg
     1141 atcctttcga acactcaaac agttgccaac aaatgaatac aagtatagtt atcaagaatt
     1201 cgtaaagcgt aggaaacaat tccaacaaag agttgtcacg cagcgaagct tgcgtcaatt
     1261 aaatcgaaca attaatgcac atgaagaaaa ataccacgca agtaaagcat atgaagagca
     1321 acagcgaaga atccaaatgg aacaagaaag acaataggag gaagagaaat gaaacaatat
     1381 ttagatcaat ggaaagtcat agaaggatca ctaaaagaag aacgaatcga acaacttcct
     1441 gattgtttag aaaaagagca tttgtttcag ataagcgaaa tgttgagaaa cgaacagttt
     1501 gatccaaatc aatttttagt tgttgagtac ccagctactg gtgtgtattg ttgtaatcat
     1561 gtgaagggtg aaaaatattt tattattcaa gaatacgaag gtaagttagc gccttattat
     1621 actacttggg aaataaatga agagggaatc aataatttcc catgtgaaag cattgaagag
     1681 tctatttctc tcacggaatg ttaaataaat agagacgtaa aagagtcctg aacgtgattg
     1741 tccaggactc tttttcaatg aattgttttc cgccaattca ctgagtggtg cgattcaatt
     1801 ttattatatc aaaagaaagt gagattccaa agtgaaggga ggaagaagaa atgactcaga
     1861 caacgattgg tgttgtggtt gaaaaaagca gggataatct cgtttttgtg acagaaattc
     1921 aaacaggtag agcttttgta gtcacagaca aagctgcaaa agcgtatcaa aatggcaata
     1981 ttttaacgtt aaatctgact acgaagatgt tcgttgatgc agtagaaaat tatccatttg
     2041 tttagacaaa cgatatttta caaggaggaa acggacatgg cagaagaaaa agaaccacta
     2101 gataatagtc ggttgggaaa gtccaaaaga aaattagtac ggttgcaaaa cgaattaaat
     2161 aatcaatttc aaaagctatt tgatcaccaa aaattgacaa atgggcaacc aatgaatgac
     2221 aaacgaaatg gtcgttcatg gtttaaccag caagaaaaaa tagaaaataa aatacaaagt
     2281 ttgagagaag agatcaagca acaagaaaaa caggtagaaa aacttgaaag acaagaagag
     2341 ctaaaggaaa tgggctataa caagtacggc ggactggata tgacgatcga taatattcca
     2401 agaatcaaag aagaaatcga acgctttgaa aaaggtgaat cgactttttc agccgccacg
     2461 atccgaaaat atcaacggaa gttggaaaca ttagaacagc tgaaagaaaa atcagaaaaa
     2521 ggaaaagaaa atatcctccc tgaagtacaa gcgatcattg acagcggacg agtgacgcaa
     2581 tggaaaaaaa atccaaccat ttattttttg aaaggctatc gaaaagttgc tttagaactg
     2641 aatgaaaacg ggggatttga ggaatcaaaa aaataccaag ccacgtcgga agaggaaaaa
     2701 gcagctgttc gtgaattact tgaagaggct gcaccaactg attctctgaa ggagaaagaa
     2761 aaagatcatt tctatcgagt agaattcaac gaaaatgatc cagaaaaagg attgaaaagt
     2821 tatggtgggg agatcgtaac attcgaattg atcgatcaac ttaaaacgtt ggataaccaa
     2881 tacgctgcag aagcaggtta ttataaattc tattttgaag aagtgaagaa cggagaagta
     2941 gtagatcaga tccgaatgga tctaggggat ggcgtcaaca gtaatcaccc catctattta
     3001 gagttagcaa aattgtgcga acaagtacct gagaaggaac aaaaacaatc ggtcaaaaat
     3061 gaacctgttt cgaaagaaca aatgcagtcg aaagaaacaa aaacaaaaca aaagggctat
     3121 caaaaacgaa cggcagaaga gatcaaacaa gaagttaaat ccctttcgca acaggcactg
     3181 gatgcggtga aaaagcatac ccattcttct gaagacgtca aagaactttt gaactttatg
     3241 tctcgttttc cagaacgatc ctttagaaat caattattga ttgaggaaca atttccaggt
     3301 gcaacggctt gtttaggtcg tgccgcgttg aaaaaagaag gaatctatat caaaaaaggg
     3361 gaacaaggga acaagatctt tgtcagaaaa acggtcaaag gattttatga gaaaggacgt
     3421 ggctttgttc gagaaacaga agctacacca gaagataaaa aacgaatcga aagtggtcaa
     3481 atcgaagtga tcaaaaaacc ttactacacg attgaaaaag tgtttgatat cacacaaaca
     3541 cagttaaaac ctgaagacta tccgaaaatc tttccgaacc gtgtctttga ttttcaattg
     3601 gataaaaaag gacagtcaga acttcaagct gggattcaag cggtagccaa caatattgga
     3661 atacaaattc gagatatgac agaaagtgaa gtctatcaaa gagaattagg acaagcacgt
     3721 ggggcgtatg ttcgtaacga atttactggc gaagaagaaa tcgtcatgaa tactcgaaat
     3781 actcctacgc agcatttagc tacaagtatt catgaattag cccatgcaag aatgcacaaa
     3841 ttttcagaat tagataccgc aactaaagaa ttgcaggcag aaatgacttc ttatattgtg
     3901 tgcaaacatt ttggaatgga cacgttggag aaagctattc cttatattgc agcatggacg
     3961 aagaatggtc a
//
LOCUS       DAYNVV010000124         3872 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.131, whole genome shotgun sequence.
ACCESSION   DAYNVV010000124 DAYNVV010000000
VERSION     DAYNVV010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.131"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..132)
                     /locus_tag="ACGXWR_002827"
     CDS             complement(<1..132)
                     /locus_tag="ACGXWR_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFK0804295.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     "
     gene            207..485
                     /locus_tag="ACGXWR_002828"
                     /pseudo
     CDS             207..485
                     /locus_tag="ACGXWR_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific recombinase"
     gene            628..849
                     /locus_tag="ACGXWR_002829"
     CDS             628..849
                     /locus_tag="ACGXWR_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0804296.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGNEIKIGN"
     gene            865..1707
                     /locus_tag="ACGXWR_002830"
     CDS             865..1707
                     /locus_tag="ACGXWR_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804297.1"
                     /translation="MKIITINDVEYAVFAANEGTSKPQPHIIETKSGTIPEGKQLSLL
                     KEYLKQNDISPIKGATTYWCIDKVLKLDSSKEKTISETIHKQKYLSLTEENIEKQHKF
                     VGASSNYGKEGLIIHDVLNAFPLHNDLNTIAMKIAVIDVTNSTHLSQYKSRLSLYDLA
                     KVILEIPNFDDRLAKGDPQLINIIARNIGAVNMFSFASKYCTYHNVEVCGRDDYSIFD
                     GIVKNTLPHYIQGLTTNKIDTWRRSFDYEAFNECVGKLLDENNIHIPFRRRKLDHFLW
                     YANR"
     gene            1770..3572
                     /locus_tag="ACGXWR_002831"
     CDS             1770..3572
                     /locus_tag="ACGXWR_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HFK0804298.1"
                     /translation="MGLFDFLKKKQGKVSKHVDYQLASSLFRTGKVFAEKLEVDISNV
                     DEFRKTFIAFDVETTGLNSSSDRIVEIGAVLFKEGVPIQSFGTLVNPKVRIAASASAI
                     NNITNEMLNSAPNEQEVYPQLVEFLGDALDGKITMCAHNASFDFGFLSNTFSRLGYDA
                     KIKYVDTLSLSRKHIKGIVNHKQETVAEYFGLINDTAHRAESDADICGKIFWGVLDII
                     EESLEEQKKQIEKMTPDIKELEACAFIQDIIEKKGCDTSWIRYRKNSNNYVDVTCLYT
                     FLKFKFAKKGNYIIIRKDATNGIDLPIEPCTVSEGGTTNVRVYFRSPFDLTPLSNYIF
                     SAYSDCYNSMNEYMSVSNYTKKEAEQSLSMLKSISKSAMKELLFDAKNRGYDETEVNL
                     NIEKVISREDVIINGLHNRVSLNKIRNIGNWEKGFDAGYPYWERGETARKNGKVDEAI
                     ALFDKARYNGYDAPALYDSYAKAYRKIKDYDNEILILDEGIMRKTRHDVGTLEARRDK
                     AIKLLFAKQEAERIAKEKSDFLKANKKEDAISEPSKKRGRQIIQMTDDGTIIKEFDTI
                     ASAVKEVGVNSKSIRDAANGVQKHAGGYYWKYKD"
     gene            complement(3631..>3872)
                     /locus_tag="ACGXWR_002832"
     CDS             complement(3631..>3872)
                     /locus_tag="ACGXWR_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HFK0804299.1"
                     /translation="PPRKNMDKSEKLDHSLLGKQRKTVGTVFSSLEKLGCQNFNSRSV
                     KGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         1374 a          562 c          774 g         1162 t
ORIGIN      
        1 atgagaaacg ttaatgccac gatcatataa gatttcttga acttcacgat agctaaggtt
       61 ataacgaaga tagtagccca cggctacaat aatcacatcc tgctgaaatt gctttccttt
      121 aaaatgattc atcgtcattc ctcctgctat ctttttctat tattctacct tatttgatag
      181 tagatttaaa actttgcaac agaaccaaag aactcatcaa gctggctaat aagggtcaag
      241 attatgaaca tctagcagat gagattgatg agctgagaga caagcgacag ctccttttag
      301 tagaagatgc ctccctcagt ggcgagaacg agcgaatcaa tgagctgatt gaatttatcc
      361 gcaagaacaa attccgtacc ttagagtacg atgataagct tgtaaggaag ataatccaga
      421 gcgttacagt ctatgaagaa cacttcgtca tatccttcaa atctggcatc gaaatggaaa
      481 tatgaaaacc agaagtaaat agcccatgat tctacagtag agtcgtgggt tttcttttgc
      541 ttgctgatta taataatatt ttaataacta ttgttattat aaaccaaatg atttataata
      601 ttcttagcgt aaacttggag gtgctgtatg actacggcag aaatgattaa agaactgtgt
      661 gagcaaatga atataagtgt ttccgaactt gctagacgta ttggacagac tccacagaat
      721 ttcaataaga aattacaacg agaaacggta accttagatg agttgaaagc gattgctgat
      781 gtgctaggtg tcaagtttgt gcaggctttt atattgcctg atggcaatga aataaagata
      841 ggtaattagg aggtgtaatt tgtattgaaa atcataacaa taaatgatgt tgagtatgct
      901 gtatttgctg ctaatgaagg tacttccaaa ccacaacctc atatcataga aacgaaatct
      961 ggtactattc cagaaggaaa acaactgagt ttattaaaag aatatcttaa gcagaatgat
     1021 atttccccaa taaaaggagc aacaacatat tggtgcattg acaaggttct taagcttgat
     1081 tcaagtaaag aaaaaactat aagtgaaaca atccataaac aaaaatactt atctttaact
     1141 gaagaaaata ttgagaaaca gcataagttt gtaggtgcaa gctctaatta tgggaaagaa
     1201 ggtctaataa tacatgatgt tttgaatgca tttcctcttc ataatgattt aaatactatt
     1261 gcgatgaaga ttgcggtaat tgatgtaaca aattcaacac atctttctca atataagagc
     1321 aggttgtctc tatatgattt ggctaaagta attctggaga ttccaaattt tgatgatcgg
     1381 ttggcaaaag gagatcctca gttgataaat attatcgcaa ggaacattgg tgcagttaat
     1441 atgttctcat ttgcatccaa gtactgtaca tatcataatg tggaagtgtg tgggagagat
     1501 gattactcca tctttgatgg tatcgttaaa aatactcttc cacactatat ccaaggacta
     1561 actacgaata agattgatac gtggcgaaga agttttgatt acgaggcatt taacgaatgt
     1621 gttggaaaac tacttgatga aaataatata catattcctt ttagaagaag aaagttagat
     1681 cacttcttgt ggtatgcgaa taggtagaat ataagaaaaa ggcatcgtaa aagtgattct
     1741 ggataaaatt aatgggggag gaaataatag tgggattatt tgattttcta aagaaaaaac
     1801 aaggaaaggt tagtaaacac gttgattatc aactggcttc tagtctattt cgtactggta
     1861 aagtttttgc tgaaaaattg gaagtggaca tatcaaatgt agatgagttt cgtaaaactt
     1921 ttatcgcttt tgatgtggaa acaactggcc taaattcttc ttcagataga attgtagaga
     1981 ttggtgcggt gctatttaaa gaaggagttc caattcaatc attcggaact cttgtcaatc
     2041 caaaagttag aattgcagcc tcagcttcgg caataaataa tataactaat gaaatgctaa
     2101 actctgctcc aaatgagcag gaagtttacc cccagttggt agaattttta ggagatgcac
     2161 tagatggaaa aatcactatg tgtgcacaca atgcaagttt cgattttgga tttttaagta
     2221 acacattttc tagacttggg tatgatgcta aaattaagta tgttgatact ctgagtctct
     2281 ctagaaaaca tataaaaggc attgtaaatc ataagcaaga gactgtagcg gaatatttcg
     2341 gattaataaa tgacactgcc catagagcgg aatcagatgc agatatatgc ggaaagattt
     2401 tttggggtgt tttagatatt attgaggagt cgttggaaga acaaaaaaag caaatagaaa
     2461 agatgactcc agacataaaa gaacttgaag cttgtgcttt tattcaagat attattgaga
     2521 aaaaaggatg cgacaccagt tggatcaggt atcgaaaaaa cagtaataat tatgtcgatg
     2581 taacttgtct atatacattc ttaaagttta agtttgctaa gaagggaaat tacatcatta
     2641 ttagaaaaga tgctacaaat ggaattgatt tacctataga accttgtact gtaagtgaag
     2701 gcggtacaac aaatgtgcga gtctattttc gtagcccctt tgacttaacg cctctttcaa
     2761 attatatttt cagtgcttat agcgattgtt ataattctat gaatgaatat atgagtgtta
     2821 gtaattacac taaaaaagaa gcagagcaaa gccttagtat gctgaaatct atttcaaaat
     2881 cagcgatgaa agagttatta ttcgatgcaa aaaatcgtgg atatgatgag actgaagtta
     2941 acctaaatat tgaaaaagtg atatctagag aagatgtaat tattaacggg ttgcataatc
     3001 gagtttcatt aaacaagata cgaaatatag ggaattggga gaaaggattt gatgcaggtt
     3061 atccatattg ggaacgtgga gaaactgcta ggaaaaatgg caaagtagat gaagctattg
     3121 cactttttga taaagctcga tataacggct atgatgctcc tgcgctatat gattcttatg
     3181 ctaaagctta tcgaaaaatt aaggattacg ataatgaaat tctcattctt gatgaaggaa
     3241 ttatgcgtaa aacacggcac gatgttggta ctttagaggc tcgtagggat aaggcaatta
     3301 agctattatt tgctaaacaa gaggcagagc ggatagctaa ggaaaaatct gattttctaa
     3361 aagcgaacaa aaaagaggat gcgattagtg agcctagcaa gaagcgtgga agacagatta
     3421 ttcaaatgac tgatgatgga acaataataa aagaattcga tactatagct tctgctgtaa
     3481 aagaagttgg cgttaactca aaaagtatta gggatgctgc aaatggagtt caaaaacatg
     3541 ctggaggata ctactggaaa tacaaagatt agcagataat ctaagataac ctaggatctt
     3601 cttaatagat acccgtggtg ctagttaatt ttaatatcct aaagaatatc tcaaagttcc
     3661 ttcaaaacgt cgttgtgctc gacttaatag aacactgtaa gccagtaata tgctttcaaa
     3721 tctactctct agccctttaa cagaacgtga gttgaaattt tgacaaccta atttttctaa
     3781 ggaagaaaaa acagtcccaa ctgtttttct ttgttttcca agtaagctgt ggtctagttt
     3841 ttctgattta tccatgtttt tacgtggcgg aa
//
LOCUS       DAYNVV010000125         3470 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.133, whole genome shotgun sequence.
ACCESSION   DAYNVV010000125 DAYNVV010000000
VERSION     DAYNVV010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.133"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            443..649
                     /locus_tag="ACGXWR_002833"
     CDS             443..649
                     /locus_tag="ACGXWR_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFK0804300.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPYTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            649..900
                     /locus_tag="ACGXWR_002834"
     CDS             649..900
                     /locus_tag="ACGXWR_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804301.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYENEYWLTKLEN"
     gene            916..1353
                     /locus_tag="ACGXWR_002835"
     CDS             916..1353
                     /locus_tag="ACGXWR_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804302.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGQWFFQALLCLEAGVKPNTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYLENVNKYGACYIMKKEDNENE"
     gene            1346..2041
                     /locus_tag="ACGXWR_002836"
     CDS             1346..2041
                     /locus_tag="ACGXWR_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804303.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEELNSKDATVDDYYLVFTKFLTCGTE
                     SIVLMGMDYELAVPEVFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNELDRK
                     RMPYQRFERKKGQ"
     gene            2206..2406
                     /locus_tag="ACGXWR_002837"
     CDS             2206..2406
                     /locus_tag="ACGXWR_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804304.1"
                     /translation="MNKIIPLLLVLFVGEILMRLSAAVHLNLAVFLVILMFCLIFWRF
                     VLALVSLLFKMIAAIFFIGLFR"
     gene            2422..2601
                     /locus_tag="ACGXWR_002838"
                     /pseudo
     CDS             2422..2601
                     /locus_tag="ACGXWR_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2663..2847
                     /locus_tag="ACGXWR_002839"
                     /pseudo
     CDS             2663..2847
                     /locus_tag="ACGXWR_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003027804.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
     gene            2881..3312
                     /locus_tag="ACGXWR_002840"
     CDS             2881..3312
                     /locus_tag="ACGXWR_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HFK0804305.1"
                     /translation="MLSEPLAKTYPAIFSPEEGGGYFIEFPDVQGAYTGINEDDISYG
                     IAMAQEVLGMVLADYIEHEDLLPEPTPINKISVEDDSFTTLIRVDVAKYLKDTELVKK
                     TLTIPQWADKLGKRAGINFSVLLTESIADKADNILRSGRNN"
BASE COUNT         1239 a          571 c          714 g          946 t
ORIGIN      
        1 agaagagctg cagtcctaaa tgaggattgc agctcttttt gttttacata gaaacaagaa
       61 aaatgaaaag gcctttttag gaaggcgcaa gcgccttctc aattgaaaaa cctctctctc
      121 actccaaccg ccaccgccgt tcgagaagaa aggaagtgaa cgttgcacgt tcactaagat
      181 aaggggtctt gcaaagcaag acaaaataga aaaaacttcc tctcaccaaa aggttcgttc
      241 ctgttcgcta tctctttatt gatttgccag accggcaaca agttgccttt tatcaccaaa
      301 aagcgacaag gacaagggta aatggcacgc tgcacgccct tgtccttgtc gcttttagtt
      361 gattcattct ggccaacaaa tcaataaaga aagaactaac gaaaggaagt aaaacctttc
      421 ctaagaggag gcagaatcaa tcatgcgaaa gaaatttgat tattggggtg ttcccttcag
      481 cgaattattc ccaaactatc atgcaccata tactgtcgaa tgcgattgtg gagaaagagc
      541 gaaatgtatc aaaagctatt gtttgtatca atgtccaaca tgcgggaaaa aatatacctt
      601 gtcttatggc gattatattt tgattgatga gaaaggaaag aaacgctgat gaaaacacaa
      661 cacaaattat tgactgtaaa agaagtcgtt caaattttgg tggacaaaga agtcatttct
      721 gaaaaagtag cagaagcttt acttattccg cggtactgga cgatagaaac ccctttagta
      781 gaggatgcac cgactatgct atttgaagac ctagtgaaga ttgcaggata tgaactgcat
      841 tatcaagaaa acatggaaac ttatgaaaac gaatattggt taaccaaatt agagaactaa
      901 aaaggagaaa aaaatatggc tcaaaattac tatgacgaat ttgtcaaatt acctttggat
      961 aaaatggcac aaaaaatgga ggatatgaca ttcctataca atgagacacg tgttccaaaa
     1021 aaacattata aggaaagatt gtcggtagct gtggaagaaa tgattgaatc gggtgtcgaa
     1081 atgaatctca ttgcgaccta ctatcgaacg cttgaagaac tgaaaaagca aaatggacaa
     1141 tggtttttcc aagccttact atgcttggaa gcaggcgtca agccaaacac tatcaaacct
     1201 tctgaatacc aagctttaga actaacgtat gggaaatttg tcgaaacgaa aaaagccaag
     1261 actgtttcaa gtgaatggtt ggactactta gaaaatgtca acaagtatgg cgcatgttac
     1321 atcatgaaaa aggaggacaa cgaaaatgaa taaggtgatt tatcaactaa caacggaaga
     1381 tgtgtcacac tttttaacaa acaaagaaca tttgaatgaa gtaatcagac ggattcaaaa
     1441 agactttagt tgtatggaag aaatgaagta ctttattcaa agagtcgaag aacaattgta
     1501 tttggaaagt gaaacgagtc aaacgaaggt tacagtcagc aataattatt tagacgtgta
     1561 taaacgtcgt cctgacacat taaaaaaagg agcggagctt ctacgactag aaacagaaaa
     1621 atatatcatg aatgtttacc tagaaaggag tgaactggtc gaaaactttg tcagctacac
     1681 gatttgcagg aaacactatt actcagaatc agaatattat tcaatttttg agagcatgga
     1741 attaatggaa gagctaaaca gcaaagatgc gacggtagac gattattacc ttgtatttac
     1801 taaatttttg acgtgtggga cggaatctat cgtgttaatg ggaatggatt atgaactcgc
     1861 tgtacccgaa gtatttttga gggaatatgt agaagaagta gataacccag gcgacgactg
     1921 gtacacgact ttaactgatt ttttagatac ctacacttac gacgatacag aagaaatcca
     1981 aaatgaactt gaccgtaaac gaatgccata tcaacgattt gaaaggaaaa aaggtcaata
     2041 accatttata ccgaaaagtg agaatgtgtg aaataaaaac aaaaaacctt gaaattaagg
     2101 gaatggttct tatttcgcac caatcgctcc aaccgccccc gccgcttagg tggtgcgaaa
     2161 taagcgagca aagcccgaaa acctaagaga aagaaggaga tttatatgaa caaaattatt
     2221 cccttattat tagtcctatt tgttggagaa atacttatgc gacttagtgc agctgtacat
     2281 ttaaacctcg cagtattttt ggtaatacta atgttttgtt tgatcttttg gcgatttgta
     2341 ttagccctcg taagtctact attcaagatg attgcagcca tatttttcat aggattattt
     2401 cgatgaaagg agagagtacc aatgccaatt gcaataggaa ataaacggtt acccgtgacg
     2461 ttggatgaaa agagacaaaa agaattgcag taaccaaagc agaagtacgg caaaagtgaa
     2521 tccaggatta tgtgtattgc gttagattta ttgattgcgc aagaaaaagc aggatttgac
     2581 ataccagcac tcaaaaagtg atcgcacttt gcgcacgtgt taatacgtgt tataattatt
     2641 ttgtaaggag gtatagtgca caatgccact tacgggaaaa gaaatgctta agttattgaa
     2701 aaaaatggct gggttgagcg aaggcaagag ggatttcatc atcatcttta taaggatggt
     2761 gttagaatca ctgttcctgt tcatgccaat caagatcttg gccgaggact tgagcgaaaa
     2821 attttaaagg atgcgggatt gaaataatct cgcattcgat taaagaaagg attgactgaa
     2881 atgttaagtg agcctttagc aaaaacctat cctgctattt ttagcccaga agaaggtggt
     2941 gggtacttta ttgaatttcc tgatgttcaa ggtgcttaca caggaattaa cgaagacgat
     3001 atatcttatg gaattgctat ggcacaagag gtgttaggta tggttttagc agattatatt
     3061 gagcatgaag atctacttcc agaaccaaca ccaatcaata agatttctgt tgaagatgat
     3121 tcttttacta ctttaattcg tgtagatgtt gccaaatatt tgaaagacac agaacttgtc
     3181 aaaaaaacct taacaattcc tcaatgggcg gataagctag gcaaaagggc tggcataaat
     3241 ttttcagtcc ttctaacaga atcaattgca gataaagcag ataacattct tcgttctgga
     3301 agaaataatt agaactcaaa agggtcagaa acttaaaaat ctttggcttc tttttttact
     3361 acaaagatgg cttctttaaa ttatttgcct gattgattta aaaaaattgc gcaaagacta
     3421 cgagctaatt aagttgctcg tggtcttttt ttatgaaaac tttttagatc
//
LOCUS       DAYNVV010000126         3241 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.135, whole genome shotgun sequence.
ACCESSION   DAYNVV010000126 DAYNVV010000000
VERSION     DAYNVV010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.135"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            1..168
                     /locus_tag="ACGXWR_002841"
                     /pseudo
     CDS             1..168
                     /locus_tag="ACGXWR_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
     gene            406..642
                     /locus_tag="ACGXWR_002842"
     CDS             406..642
                     /locus_tag="ACGXWR_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804306.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            649..2601
                     /locus_tag="ACGXWR_002843"
     CDS             649..2601
                     /locus_tag="ACGXWR_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HFK0804307.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2673..3170)
                     /gene="dfrG"
                     /locus_tag="ACGXWR_002844"
     CDS             complement(2673..3170)
                     /gene="dfrG"
                     /locus_tag="ACGXWR_002844"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HFK0804308.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
BASE COUNT         1147 a          536 c          570 g          988 t
ORIGIN      
        1 tctctgttcc ctctttatca tggaagtgca aaaagtaata tagggattga taaccttata
       61 gaagttatta ctaataaatt ttattcatca acacatcgag gtccgtctga actttgcgga
      121 aatgttttca aaattgaata tacaaaaaaa agacaacgtc ttgcatatta agtagttcag
      181 ttttggagta caaaaagtga aaatgtaaac ctaaatgagt atcaaattgc aactgaattt
      241 gatactcgtt ttttattgtt aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag
      301 ttaaaatgta tataaaaatg cgaacgtgaa ataattattg taggaatgca aattggtgtg
      361 ttaaaatggt tacaatttac taagcaaaaa ggggtgcatt ttcctatgca atttcttgag
      421 ccaaaaaata agaacgctaa gtctgtggat tgggaaatat cagagcaagt aagggtgata
      481 gttaagcaat acgctgaata tgcagagcgt actgaaagcg aagcagtgga tgaattctta
      541 ttgaacattt tagacgataa gaagtttatt gaatggattg ccaacaagcg aagtaataag
      601 cggattgttg aaaaaatggg tatcaaagat agagtgggtt gatagacaat gaccaagctt
      661 aaaagattag ccacgaagga agatgaaatt gtagatgtta aaattccgat ttcaaacgaa
      721 gaattaaaag atagggctaa acaatatgat ttattaactc caaaacgatt tgcaacaagg
      781 tataacaaaa tgttgttctt gccaacgtct tttaaatgga acggttctga atatcccatt
      841 caatataatt actgcatcaa tccgttttgt tgtaattttg ggaaagaaca gcacaaattc
      901 aaagatgtaa aagggaaacc aagtcgatat aaaatgactg gtagttccaa agataaaggt
      961 cataaaggta tgtactgcaa tgacaatcct attggcagag gtgtatcgca aaactgtaca
     1021 gtaacccctt tatctaattg gtctgttgtt gaagaaatta aacgccttat agaaatcaat
     1081 agcatccaag atgttgagcc agattatcaa tttcataaag aaggctgctc ggaagaagaa
     1141 tcaaccccat tcaatgagcc gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct
     1201 caacgctatc aatgtaaggc gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa
     1261 accactactt atcaccaaca aaagaacacc attcttccaa tgttcgctaa gatggttgtt
     1321 ggaagggttt cagtcagtcg tacttgtgat attttaggaa ttggagttgg aacctactat
     1381 cataagctgg agtggctgta taggcgttgt ttggagtttt tagaacgata tgagacacaa
     1441 ccccttcaaa caaagaaatt taacgagatg tggcttaata cggacaagat gcactactac
     1501 ctaaataacg tccgtaagaa aggacaaggt tcaaagaaat atacggggtt tgaagacctt
     1561 aatatgcaaa cgtatatagt tgtatctgct gaggtcttat caagatatgt gttccgttct
     1621 gatgttgcct atgattggaa tatttcaatg gatgaattaa atgaagatac aagaaaattc
     1681 aaagaagacc atctcaatac ttttagtcgt aaaaatgata ggttagattg gtcttattat
     1741 ccacaagaac catccgctaa cgatagcgaa aataggaatg cttatcttca cgaattaggg
     1801 aaaattacta ataggagtag atttgtcgat ggtttaaatg ttgatgctcc ttatactaca
     1861 actgctcact attggttaat taaacaaatg gttaatgccg acgaatggcg aatgattagt
     1921 gatgatgact tctctattag aaacgccttt tatagagtat tcacgaaaga attaaggttg
     1981 agcgatgcac atcattttat ttgccaagtt aacaagacga aaagcagaaa acaatgctta
     2041 aaagaattcg gacaagcaaa agcagaactg ctcgattggg gagatatcag aggattcaaa
     2101 acaaagtttc tacggacttt ggcatctcat tatctaactg aattactaac aagtcatcaa
     2161 ttccacgaag aggctattag taaagatgga gaaagatatc gcaaatatgc cgataaccct
     2221 atcaaacatc cattagccac taaggataaa ggattttatt cagttgattg tagaacggat
     2281 ttatctgctc tggaaccaaa cgaaatcgca aagatgctat taaatgttaa tgaccattcg
     2341 accaatagct ttattcaaca gataagacgt tatatatcat ctcttgaaag accattaaca
     2401 acagctcgtg gtgataagaa gagctatatt tacgctaact tcaatccgaa gtatgctcaa
     2461 tttgcgatta caattctaag aacttactac aacttttgtc gcccttttaa atcagcggat
     2521 aaaaaggttt tgacacctgc tcaaagatta gggattacag ataaacaatt tgattggaaa
     2581 gatataattt atttcaaatg acaaaaagag cttggagtaa tcccaagctc ttgtgcttta
     2641 tctttactgt tcttcttcaa ttaacgcacc cgttaactca ataagttttt tctttcatat
     2701 acatgaaaat agtagttata cggattttta tcattcttta tccctttttg ggcaaatacc
     2761 tcattccatt cctcataatt cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt
     2821 atttttgtga tgtacatttt ctcaacataa gggaaaaaca aattataaat ctgttctcct
     2881 ccgaaaataa aaatttcttc ttcgttttta cataactcaa aaacatcttc tattgaatga
     2941 acaatttcac aaccattaaa ggtaaacccc ttatctctcg tcagaataat atttcttctg
     3001 tcaggtaagg ctcttccgat tgattcaagg ttcttcctac ctaatattat cggatgtccc
     3061 tttgtagtat ttttaacata ttcccagtcc ttgggaatcc tccaaggaat gtcattctct
     3121 ttgccaatca ctctattctt atccatcgca gcaatcaaag aaactttcat ttataacaca
     3181 gcctttttaa ctaatttacc atctaatttc ttatttctat caaaaaacct tttctcatta
     3241 t
//
LOCUS       DAYNVV010000127         3218 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.136, whole genome shotgun sequence.
ACCESSION   DAYNVV010000127 DAYNVV010000000
VERSION     DAYNVV010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3218
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.136"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..1438
                     /locus_tag="ACGXWR_002845"
     CDS             <1..1438
                     /locus_tag="ACGXWR_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HFK0804309.1"
                     /translation="SKKNQPKDIKDIVDTRMYKERDDLNYTLIINKDGNYSWRPLVLL
                     HPILYVDLVNCLTKEDHWEELKKRFSEFKKDKNINCYSIPVEASKGSKRTDLGETILN
                     WWEYFEQKSLAQNIKYQYCMFTDIADCYPSIYTHSITWAMYGKEKVKNDENKCSGSLG
                     DKIDKKISGMQHNQTNGIPQGSVLMDFVAEIVLGYVDLRLSKELKKLENLKDYKVLRY
                     RDDYRIFSNNRNDLEQIMKVLSEVLYDLNFKLNSSKTKLSDDIIIDSIKKDKLYWEEI
                     KASIRMNATNLDGDREIRYSINLQKHLLEIKKLADKHPNSGQLKKALSEFNKERIIKI
                     TSKPNDLLPLIGILVDIMINNPGSLPQCVLIIGQLLNFENESKAREIVEMIINKYALK
                     PNTEFMMIWFQRLTTIFGEMFDSVLSSEFVSKIKDPVSNQMFSVDWLNEDAKKSFYEG
                     TIKDEEKYIKMSKKIYITEFDDFNDYPF"
     gene            1776..>3218
                     /locus_tag="ACGXWR_002846"
     CDS             1776..>3218
                     /locus_tag="ACGXWR_002846"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HFK0804310.1"
                     /translation="MTEQIEKNSKSLYQALWNSADILRSKMDANEYKSYLLGLVFYKY
                     LSDNMLRYVSVLLEEETDDLNKAQDLYVEAFKDADIKDDLLYELKDEFSYTIAPALTF
                     TAQVAAIHDGSFQLEDLVQGFRDIEQSSENFENLFEDIDLYSKKLGSTPQKQNKTIAD
                     VMKELEGLNMAGHAGDVLGDAYEYLIGQFASESGKKAGEFYTPQPVAKLMTQIVLQGK
                     EDKKGFSVYDATMGSGSLLLNAKKYSHQPGTISYFGQELNTSTYNLARMNMILHGVPI
                     ANQHLHNADTLDQDWPTEEPTNFDGVLMNPPYSAKWSADKGFLDDPRFSAYGVLAPKS
                     KADFAFLLHGYYHLKDTGVMAIVLPHGVLFRGGAEGKIRKTLLENGAIDTVIGLPANI
                     FFNTSIPTTVIILKKDRAKKDVLFIDASQDFEKIKTQNTLRDYHIDAILEAYKTRTIK
                     DKYAYVAEFDEIVENDYNLNIPRYVDTFEEE"
BASE COUNT         1184 a          505 c          581 g          948 t
ORIGIN      
        1 ttcaaaaaaa aaccaaccga aagatataaa agatattgta gatacacgaa tgtataaaga
       61 acgtgatgac ttaaactata cgcttattat caataaagat ggaaactatt catggcgtcc
      121 tctcgttcta ctacatccta ttctatatgt agatttggtt aattgtctca ctaaagaaga
      181 ccattgggag gagttaaaaa agaggtttag tgaatttaaa aaagataaaa atattaactg
      241 ttattctata cctgttgaag cttccaaagg ttcaaaaagg acagatcttg gtgaaacaat
      301 actaaactgg tgggaatatt ttgaacaaaa aagcttagct cagaatatta aataccaata
      361 ttgcatgttt actgacatcg ctgattgtta tccatcaatt tatactcact ctataacatg
      421 ggccatgtat ggtaaagaaa aagttaaaaa tgatgaaaat aagtgttcgg gctcacttgg
      481 cgataaaata gataaaaaaa tatctggaat gcaacacaat caaacaaatg gtatccctca
      541 gggttccgtt cttatggatt ttgtagcaga gatcgttcta gggtatgttg atttgagatt
      601 atcgaaagaa ttaaaaaaat tagaaaattt aaaagattac aaagtactca gatatagaga
      661 tgattataga atattttcaa ataatcgtaa tgatttggaa caaattatga aagtgttatc
      721 agaagtctta tatgatttaa attttaagtt aaattctagt aaaacaaaat tatcagatga
      781 tattatcata gattctatca aaaaagataa gctctattgg gaagaaatta aggcaagtat
      841 aagaatgaat gccacaaact tagatggtga tagagaaatt cgttatagta taaatttaca
      901 aaaacattta ttggaaataa aaaagttagc agataagcat cctaattcag gccaattgaa
      961 aaaagcactt tctgagttta ataaagaacg cattattaaa atcacttcaa agccgaacga
     1021 tcttttacca cttattggta tcctggtaga tatcatgata aataacccgg gttctttgcc
     1081 gcagtgtgtc ttaattatag ggcagttatt aaatttcgaa aatgagagta aggctagaga
     1141 aatagttgaa atgattataa acaaatatgc tttaaagcca aatactgaat ttatgatgat
     1201 atggtttcaa agattgacca ccatttttgg agaaatgttt gatagtgttt tatcatccga
     1261 atttgtatct aaaatcaaag atcctgtctc taatcagatg ttttctgtag actggctaaa
     1321 tgaagatgct aagaaatctt tttatgaagg gaccattaaa gacgaagaga aatatattaa
     1381 aatgagtaag aaaatatata ttactgaatt tgatgatttt aatgattatc ctttttaagt
     1441 gaaaatttag aatgaatata aaaaacatta caatctaatt tttttaaaaa aatgttatat
     1501 cggaagtaat ctcttgattt ctatactata agataagaaa accactattt aacaaggtta
     1561 ttcgaacctt attttaagtt acttattatt taatgtatcg aaaaaggtga aataggtttg
     1621 ttataataag aattaagtaa gacatgaatt gtctaagcaa atgtagctta tccatttcat
     1681 taaaatacat atggtgaaaa aacaagttca aatagtaact aattttttaa aaaactgatt
     1741 tataaaaaat acaacacgaa tgaggaaaat aaccaatgac agaacaaatc gaaaaaaatt
     1801 caaaaagctt atatcaggca ctgtggaatt ccgcagatat cctgcgttca aaaatggacg
     1861 ctaatgaata caagagctat ttactaggct tggtctttta taaatactta tccgacaaca
     1921 tgctgcggta tgtctccgtt ctattggagg aagaaacgga cgacctaaat aaagcacaag
     1981 acctttacgt tgaagcattt aaagatgcag atataaagga tgatctcttg tatgaactaa
     2041 aagatgagtt ttcatatacc atcgcacccg cattgacctt taccgcgcaa gtggcagcca
     2101 ttcatgatgg atcttttcaa ttagaagacc tggtacaagg tttccgtgac attgaacaat
     2161 ccagcgaaaa ctttgagaac ttatttgaag acattgatct gtattctaaa aaactggggt
     2221 caaccccaca aaaacaaaat aaaaccatcg cagatgttat gaaagaatta gaagggttaa
     2281 acatggcggg gcatgctggc gatgtcttag gcgatgccta tgagtactta attggccaat
     2341 tcgcatctga atccggtaaa aaagccggtg aattctatac cccacaaccg gtcgcaaaat
     2401 tgatgacaca aattgtttta caaggaaaag aagataaaaa aggcttttct gtttacgacg
     2461 cgaccatggg ttcgggctcg ttacttttga acgctaaaaa atattcccat caaccgggaa
     2521 ccatttctta tttcggacaa gagttgaata cgtctaccta taatttggcg cgtatgaaca
     2581 tgattttgca tggggttccc attgccaacc aacacttgca taatgcggat accttggatc
     2641 aagactggcc aacagaagag ccaacgaact tcgatggggt gctcatgaac ccaccgtatt
     2701 ctgcaaaatg gtcggctgat aaaggcttct tagatgaccc acgcttctct gcctatggcg
     2761 tattagcccc taaatcaaaa gcggactttg ctttcttatt acatggctac tatcatttga
     2821 aagatacggg cgtcatggcc attgttttgc cacatggggt gctctttaga gggggcgcag
     2881 aagggaagat acgcaaaacc ttgttagaaa atggtgccat tgacaccgtc attggcttac
     2941 ctgctaacat cttctttaat acgtccattc caacgaccgt aattatcttg aagaaagacc
     3001 gtgcgaaaaa agatgtgctc tttattgatg cgtcacaaga ttttgaaaaa ataaaaacgc
     3061 aaaatacgct acgagattac catattgacg ctattttaga ggcctataaa acccgtacaa
     3121 ttaaagacaa gtatgcttat gtcgcagaat ttgatgaaat tgtggagaat gattacaact
     3181 taaacattcc ccgttacgtg gatacctttg aagaagaa
//
LOCUS       DAYNVV010000128         3201 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.137, whole genome shotgun sequence.
ACCESSION   DAYNVV010000128 DAYNVV010000000
VERSION     DAYNVV010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3201
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.137"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            677..763
                     /locus_tag="ACGXWR_002847"
     CDS             677..763
                     /locus_tag="ACGXWR_002847"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFK0804311.1"
                     /translation="MFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(1065..1289)
                     /locus_tag="ACGXWR_002848"
     CDS             complement(1065..1289)
                     /locus_tag="ACGXWR_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804312.1"
                     /translation="MEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNMTPERKRS
                     LEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
     gene            1655..1939
                     /locus_tag="ACGXWR_002849"
     CDS             1655..1939
                     /locus_tag="ACGXWR_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804313.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            1942..2358
                     /locus_tag="ACGXWR_002850"
     CDS             1942..2358
                     /locus_tag="ACGXWR_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804314.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(2495..>3201)
                     /locus_tag="ACGXWR_002851"
     CDS             complement(2495..>3201)
                     /locus_tag="ACGXWR_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFK0804315.1"
                     /translation="ELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLKKVRFS
                     FEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEINKTKK
                     FVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYYVVRIE
                     EFRSLMDIPEYYQMGNIDQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLEFTFSS
                     LTSDLPKISLRNWLEE"
BASE COUNT         1065 a          598 c          500 g         1038 t
ORIGIN      
        1 cgttttttca tccattcctt tcttcccccc ttacaaataa ataataacct ttaacaacca
       61 actcgtaaat aggttggttg ttattataca aaaggatatt agtactcaga taaaaagttg
      121 ttagtactca gataaaaagt tgttagtact cagataaaaa gttgttagta ctcagataaa
      181 aagttgttag tacccttctg tatccgttgg gagagtaagg ctcaactgcc ccctaaaaag
      241 ggttctaaaa aatctttaaa aaataaataa aataaacgcg cgcgcgcgag caaaatttcc
      301 cgccaaaaaa tcacccactt tttaaaataa acaggttcgc gcatgatatt aaactgccaa
      361 tctagctccc tatggtcgct gtaagaagga gtgatcgcta cgctctcaca ttttacttgc
      421 agcagtcgcc tttaggctcc ttcgccaaaa ataattcatt agggactcct ttgtggcgtc
      481 ctgagagctc gtctaagccg ttctaagaca agattcgata aaaactatgt ccttcgttct
      541 aaagcgcctt acaggcggtc agggcaagcc ctaacaaccc caaggcaata aaaaacttag
      601 gcttattttt gcttttttat tgtataattg attgtcgcct atccgacagt cttgcgactg
      661 gaaggaggtg tgtttcgtgt tcactaactt tatttgctcc cttcttgttg ggcttttaag
      721 cgctttgttc agttactggt tgaataaccg aaacaagaag taaaacttaa ttaaggcgac
      781 tcagcccaca aaaaaagccc cagagaatcc gacctctctg gggctttcgt gtgtttcgtg
      841 ttcacttatt tgcaatcaaa ttataacaga aataaatatt tatttcaaaa atatcctaca
      901 aaagtctaaa atccgtaatt atttcttata tgcaacattt acaaataaag tcgctctgag
      961 agctcgtatt tttcgattta agacgtttta tttagttttt ggtgtatttc attggtccaa
     1021 gctaaaaaac tcttagaagc gattttagag ccatttaaac ccacttaatt atattctcca
     1081 tgaaattcgc tccatgcgtc aaaagctgcg tctgaaattc cgccgtcttc gttcactagt
     1141 tgcattaatt tttccaacga tcgttttctt tcgggtgtca tatttttata ttccaacaat
     1201 ttttcgtctg ttaaatcgaa cttgattgct tgaattgctt gctctaattt ttctaagttt
     1261 tgaaaatatt cgtaaggaaa tttttccatt ttttctttct ccagtctcac aatttttcta
     1321 gaaataaaat cacttctttg ccgtctatac tctcaaaaaa aatgtcgttt gaaaaactaa
     1381 ataaattttt gatcgtgcat ttttaaattt ggttatcgat tacacgtgca gcactccccc
     1441 ccgaatttta aagagcataa ggaaacgtgt acccactttc taaaaaaagt gggtagatag
     1501 gctgtgccta tcacgtttct cagaaaaaaa tttgatatca ctttttcgcc atcgtgggta
     1561 gcttatgtat agcattttgg caaaaaacag ctatacaaat atagtatttg tatggtatac
     1621 ataaattata cataattgca aaaggagatt ttttatggac attttagttc ggaatattga
     1681 tccaaagttt gttgcaacaa tagacaaacg ttgccaagaa ctcacgaata aaacaggaga
     1741 aaaatggagt cgaaataaat atctaaaagt tttaatcgaa agtgattttg accgtcaact
     1801 tacgacttac aaaaaagacc aattcgattt attgctcgat aaatttattg ctatccaaac
     1861 agaaaatact caaatattaa gcgagtatgt ctacacaaat aatcaaatca ttgaaatgct
     1921 tatcggagga atgatataac catgagaaaa acttctgtcc aaaaacatgt tactttgtac
     1981 cctagtcatg ttgacgtttt agattccatc atcgaaaaaa atccagatat caataactac
     2041 tcggaagcca ttcgcttttt atgtatgagt tatgaacccg ataccaacac gaccactacc
     2101 agcaatcagg caaaactaaa tgctatggga aaagaaattt ccatcatgac tgaaatcatc
     2161 gcagaatttg ctgatttata tctaaaagat acaggcgttc ttattggcac aaattctaaa
     2221 gtatatcaag aagtgaaaga aaaaatcgaa gctaaactaa atccatcaaa tcgaaatcga
     2281 ccaaagaatc atcaaaaaga aaccagtcaa acagtcactt ctagaaattt cgacccaaca
     2341 aattttctaa aacgataaaa aacagatagg agttattcct atctgttttt tatttagaag
     2401 ccccatacaa tatgctagaa tgtactagca atcttagtcg gttgtaaggg acttgtctac
     2461 ttgcttaatg taaggggggc gagttctttt ttatttattc ttctaaccag ttacgcagag
     2521 aaatctttgg caaatctgac gttaggcttg aaaaagtaaa ttctaatttg gcgattttat
     2581 tgcccttttt tgcttttatt tttgtgactt taagatcatt gaagtatttt tttagttctc
     2641 gtaatgcagg atttaatact ttttgatcaa tgttacccat ttgatagtat tctgggatat
     2701 ccattaagct cctaaactct tcaatacgaa ctacataata accagtagaa cggtactgca
     2761 taagcagtcg gaatagagtt tttgcatacg tagaacgcaa cgacgtgaaa gcagataatt
     2821 caaatctact aaattcagct gttaaaccat taataatata ttctaggtcc ggattaacac
     2881 tgacttcaac aaactttttt gttttattga tttcaaaacc agtaaacaaa acaaagtagc
     2941 gaatagaatc ctcatcttca gtacggtaag taagattaag catatcttta tagagctttt
     3001 ctaaatcacc gacaaaggct tttgtagcag tcatcttata atcacttaac tcttttaatt
     3061 cctcgaaaga aaatctaact tttttcaaac cacgatcttt catacgagcg cataatgcaa
     3121 aaaataaatc catctgctta gcattgaaat ttttcagcgg tactaaattc aattcatttt
     3181 gatatttgac tgttaattcc g
//
LOCUS       DAYNVV010000129         3196 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.138, whole genome shotgun sequence.
ACCESSION   DAYNVV010000129 DAYNVV010000000
VERSION     DAYNVV010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3196
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.138"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            201..1169
                     /locus_tag="ACGXWR_002852"
     CDS             201..1169
                     /locus_tag="ACGXWR_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFK0804316.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1162..2193
                     /gene="vanA"
                     /locus_tag="ACGXWR_002853"
     CDS             1162..2193
                     /gene="vanA"
                     /locus_tag="ACGXWR_002853"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFK0804317.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2199..2807
                     /locus_tag="ACGXWR_002854"
     CDS             2199..2807
                     /locus_tag="ACGXWR_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFK0804318.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          948 a          610 c          778 g          860 t
ORIGIN      
        1 tttttaggaa aatctcaagg ttatctttac tttttcttag gaaattaaca atttaatatt
       61 aagaaacggc tcgttcttac acggtagact taataccgta agaacgagcc gttttcgttc
      121 ttcagagaaa gatttgacaa gattaccatt ggcatccccg ttttatttgg tgcctttcac
      181 agaaagggtt ggtcttaatt atgaataaca tcggcattac tgtttatgga tgtgagcagg
      241 atgaggcaga tgcattccat gctctttcgc ctcgctttgg cgttatggca acgataatta
      301 acgccaacgt gtcggaatcc aacgccaaat ccgcgccttt caatcaatgt atcagtgtgg
      361 gacataaatc agagatttcc gcctctattc ttcttgcgct gaagagagcc ggtgtgaaat
      421 atatttctac ccgaagcatc ggctgcaatc atatagatac aactgctgct aagagaatgg
      481 gcatcactgt cgacaatgtg gcgtactcgc cggatagcgt tgccgattat actatgatgc
      541 taattcttat ggcagtacgc aacgtaaaat cgattgtgcg ctctgtggaa aaacatgatt
      601 tcaggttgga cagcgaccgt ggcaaggtac tcagcgacat gacagttggt gtggtgggaa
      661 cgggccagat aggcaaagcg gttattgagc ggctgcgagg atttggatgt aaagtgttgg
      721 cttatagtcg cagccgaagt atagaggtaa actatgtacc gtttgatgag ttgctgcaaa
      781 atagcgatat cgttacgctt catgtgccgc tcaatacgga tacgcactat attatcagcc
      841 acgaacaaat acagagaatg aagcaaggag catttcttat caatactggg cgcggtccac
      901 ttgtagatac ctatgagttg gttaaagcat tagaaaacgg gaaactgggc ggtgccgcat
      961 tggatgtatt ggaaggagag gaagagtttt tctactctga ttgcacccaa aaaccaattg
     1021 ataatcaatt tttacttaaa cttcaaagaa tgcctaacgt gataatcaca ccgcatacgg
     1081 cctattatac cgagcaagcg ttgcgtgata ccgttgaaaa aaccattaaa aactgtttgg
     1141 attttgaaag gagacaggag catgaataga ataaaagttg caatactgtt tgggggttgc
     1201 tcagaggagc atgacgtatc ggtaaaatct gcaatagaga tagccgctaa cattaataaa
     1261 gaaaaatacg agccgttata cattggaatt acgaaatctg gtgtatggaa aatgtgcgaa
     1321 aaaccttgcg cggaatggga aaacgacaat tgctattcag ctgtactctc gccggataaa
     1381 aaaatgcacg gattacttgt taaaaagaac catgaatatg aaatcaacca tgttgatgta
     1441 gcattttcag ctttgcatgg caagtcaggt gaagatggat ccatacaagg tctgtttgaa
     1501 ttgtccggta tcccttttgt aggctgcgat attcaaagct cagcaatttg tatggacaaa
     1561 tcgttgacat acatcgttgc gaaaaatgct gggatagcta ctcccgcctt ttgggttatt
     1621 aataaagatg ataggccggt ggcagctacg tttacctatc ctgtttttgt taagccggcg
     1681 cgttcaggct catccttcgg tgtgaaaaaa gtcaatagcg cggacgaatt ggactacgca
     1741 attgaatcgg caagacaata tgacagcaaa atcttaattg agcaggctgt ttcgggctgt
     1801 gaggtcggtt gtgcggtatt gggaaacagt gccgcgttag ctgttggcga ggtggaccaa
     1861 atcaggctgc agtacggaat ctttcgtatt catcaggaag tcgagccgga aaaaggctct
     1921 gaaaacgcag ttataaccgt tcccgcagac ctttcagcag aggagcgagg acggatacag
     1981 gaaacggcaa aaaaaatata taaagcgctc ggctgtagag gtctagcccg tgtggatatg
     2041 tttttacaag ataacggccg cattgtactg aacgaagtca atactctgcc cggtttcacg
     2101 tcatacagtc gttatccccg tatgatggcc gctgcaggta ttgcacttcc cgaactgatt
     2161 gaccgcttga tcgtattagc gttaaagggg tgataagcat ggaaatagga tttacttttt
     2221 tagatgaaat agtacacggt gttcgttggg acgctaaata tgccacttgg gataatttca
     2281 ccggaaaacc ggttgacggt tatgaagtaa atcgcattgt agggacatac gagttggctg
     2341 aatcgctttt gaaggcaaaa gaactggctg ctacccaagg gtacggattg cttctatggg
     2401 acggttaccg tcctaatcgt gctgtaaact gttttatgca atgggctgca cagccggaaa
     2461 ataacctgac aaaggaaagt tattatccca atattgaccg aactgagatg atttcaaaag
     2521 gatacgtggc ttcaaaatca agccatagcc gcggcagtgc cattgatctt acgctttatc
     2581 gattagacac gggtgagctt gtaccaatgg ggagccgatt tgattttatg gatgaacgct
     2641 ctcatcatgc ggcaaatgga atatcatgca atgaagcgca aaatcgcaga cgtttgcgct
     2701 ccatcatgga aaacagtggg tttgaagcat atagcctcga atggtggcac tatgtattaa
     2761 gagacgaacc ataccccaat agctattttg atttccccgt taaataaact tttaaccgtt
     2821 gcacggacaa actatataag ctaactcttt cggcaggaaa cccgacgtat gtaactggtt
     2881 cttagggaat ttatatatag tagatagtat tgaagatgta aggcagagcg atattgcggt
     2941 cattatctgc gtgcgctgcg gcaagatagc ctgataataa gactgatcgc atagaggggt
     3001 ggtatttcac accgcccatt gtcaacaggc agttcagcct cgttaaattc agcatgggta
     3061 tcacttatga aaattcatct acattggtga taatagtaaa tccagtaggg cgaaataatt
     3121 gactgtaatt tacggggcaa aacggcacaa tctcaaacga gattgtgccg tttaagggga
     3181 agattctaga aatatt
//
LOCUS       DAYNVV010000130         2856 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.140, whole genome shotgun sequence.
ACCESSION   DAYNVV010000130 DAYNVV010000000
VERSION     DAYNVV010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.140"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(606..962)
                     /locus_tag="ACGXWR_002855"
     CDS             complement(606..962)
                     /locus_tag="ACGXWR_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFK0804319.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(976..1386)
                     /locus_tag="ACGXWR_002856"
     CDS             complement(976..1386)
                     /locus_tag="ACGXWR_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFK0804320.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            1605..2342
                     /locus_tag="ACGXWR_002857"
     CDS             1605..2342
                     /locus_tag="ACGXWR_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFK0804321.1"
                     /translation="MTTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVLKGIE
                     IGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFAQLSE
                     ALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKSAYLY
                     DNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKAKGVTELAIYQKG
                     KRIMVPLPVQKNVLSIKSEDVFLDFFF"
     gene            complement(2325..2822)
                     /locus_tag="ACGXWR_002858"
     CDS             complement(2325..2822)
                     /locus_tag="ACGXWR_002858"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFK0804322.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
BASE COUNT          883 a          514 c          446 g         1013 t
ORIGIN      
        1 tgtttgttgt cttgaattga atcaagacgc cctacacatt tggtttgtct tactttgttc
       61 agttttcaaa ggtctacttc atcaggagtg ttccccgatt cgtttttggc tgccgtagca
      121 acttttatat catatcagag agacaagtaa ttgtcaactc ttttttaaaa gtttttttga
      181 tttcgttttt cgaaatctta cagcaactca tttatcataa cttatcattt gttatttgtc
      241 aagaactttt ttgaagtttt tttcgataga atcaagcttc acaagtggtt cttttttaac
      301 aactcagtta tcttatcatg tcatttctaa catgtcaaca actattttat atgtttttta
      361 aaatactatt ttattgcttt gctacttaaa acaacagaaa tgaatatatc atgtaaattt
      421 acacatgtca atatattttt aactctatat ccccacctag atttgaattt tgaccacata
      481 aattgagcat gtctctatag tagaaaaata aagtcaaaaa aagaacacat aacacgcttg
      541 atgctaagtg ttcgactgtt acaactgtat gaaatgctca gtgacttgat taaaacagtt
      601 aaagtctatt tatttaagat aagctgttcc atcaactgct cattgtatcc aataaataga
      661 acttcatcga taataatcaa aggacgtctg aggagattgg tatgttgtgt gcataaaaaa
      721 atcagttgtt tttttcctac acaggaaagg tcaatcgcaa tgttgtgaaa agcctcagac
      781 caagtcgcaa atagctgttc tgcttgcact tcttcaaaac tgcataattc ttctgcttct
      841 tctgtactta gatcgcgttc ttctaagtca acaaattgat aaggcaattg atggtgttct
      901 aaccattgtt tcgccttcag acttgttaca cagtgcgctg atccatagac tttcacttcc
      961 acgaaggctc cctccctatg aatttaagat gttattgttt tgtaaataga tcagatttct
     1021 ggcaacacat cgaatttcac gagggacaaa tgaccggatc tcatcttcat taaatccgat
     1081 tagtattctt ttttcatcaa tcaaaatagg tcgtctcaat aatgaaggat attctttgaa
     1141 taagacgatc atttgcttta aagttaattc gttaaaatct atgcccagct tttcgtaaat
     1201 tttcgaccga gtggaaataa tatcttgaac tcctccttca gtcgctgcca agatcttttt
     1261 gatctcactt tctgttaacg gttcggcaaa aatattcttc tcttcaaatt caagttgatt
     1321 cgcttgcaac catgctcttg cttttctaca ggaagtacag ctaggcgaag tatatacttt
     1381 tatcattttc tcactccttt ttaattataa tccaattcta cagtaatttc ttttaaaata
     1441 ccaattatta gctaataaaa tataaaaaaa aacccgtggt gctagttaat tttttcctag
     1501 aggaaaatgt ctaaacatgt tggtaaatca acaaaaaaac gcatatagta gtctcaaaac
     1561 tcccaagaaa tgaggactat ttaacaaact acgatggtta cgtcgtgaca actgaacatt
     1621 ttgacttagc caatcctgtt actaaagtcg atgatatccc cgattatgaa atgtacagtc
     1681 aaacaatcga tagcttaaat aagcgttttg gcaatcgtgt tttaaaaggc atcgaaatcg
     1741 gttacatcgc ttctgaaaag gatcggatca tcgactattt agccgataaa gattacgatt
     1801 taaaattact cagtgtgcat cataatggtc aatttgatta tttagatgac gaagtcaaag
     1861 atatggatcc tgctattgtg attcctcagt attttgcaca actttcagaa gcactagttg
     1921 ttatagaagc agatgtcttt gctcattttg actatggttt tcgggtattt ggtctatccg
     1981 ttgctgaatt taaacaatat gaagcgcagt ttttaccgat tctagatcaa gtaattaaaa
     2041 ataaattggc attcgaatta aatgctaaga gcgcttactt gtatgacaat ttagcgttat
     2101 atgaatatgt catcgattta tatctttcac gtggtggtac cttgtttagt gttggatcag
     2161 atgggcatta ccttgaacat ttccgtttcc atttcgatga tctttttgct ctgttaaaag
     2221 caaaaggtgt gacggaatta gcgatttatc aaaaaggaaa gcgaattatg gttccattac
     2281 cagtccaaaa aaacgtcctc agcatcaaaa gtgaggacgt ttttttagat ttctttttct
     2341 aaaatcggac aaatacgatc ttgttttcct aaaggaaaat gtttgatccc gattttttta
     2401 aatccatgac gttcataaaa acgaatacct gcatgatttt tttcataaac agtcaaacgt
     2461 aaataacgtt tttgtttcgt tttagcataa cgattcgctt catcgagtaa ccgttgccct
     2521 aaccctttgt tttgataatc tttgagcaga tagagccgtt gaatctctat agcatctttt
     2581 tcatcattga ctttcatata accaatgagt atttgatgat ccttaatacc aataaattta
     2641 ctggttgact gtgccaattc tactgccaat atttcagttg tcaattgtgt ctgtaaatat
     2701 ccttgcatat caagtggatc tgcgccatcg ataaacgatt cataaaaact gacaacactt
     2761 acaacttgta aagcatctag atcatcataa tctaaatacg ctagtgtgat ttgattgttc
     2821 atctaactcc tccttttgac atagtatact ataaat
//
LOCUS       DAYNVV010000131         2737 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.141, whole genome shotgun sequence.
ACCESSION   DAYNVV010000131 DAYNVV010000000
VERSION     DAYNVV010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2737
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.141"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(58..402)
                     /locus_tag="ACGXWR_002859"
     CDS             complement(58..402)
                     /locus_tag="ACGXWR_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804323.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(478..1725)
                     /locus_tag="ACGXWR_002860"
     CDS             complement(478..1725)
                     /locus_tag="ACGXWR_002860"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HFK0804324.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            complement(1722..2528)
                     /gene="proB"
                     /locus_tag="ACGXWR_002861"
     CDS             complement(1722..2528)
                     /gene="proB"
                     /locus_tag="ACGXWR_002861"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HFK0804325.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
BASE COUNT          771 a          570 c          522 g          874 t
ORIGIN      
        1 aagtccggca gttttttgcc gatcttcaag gcactctact tatcgtacgg atatttttta
       61 gcggaaagtc cgattcaagt ggtttttatt cagctgatat ttataagata agtgaaaaat
      121 cccagcaatc agtagcgtaa tcgtataagc gattgaatga tcgaaaaaag aatagtaatt
      181 gattgtcgct aataagcata atgcaaccat gtaactaatg tgcaagcgtg taaccagccc
      241 tttttgcccg attttgtcaa aatactgcga ccatttttcc cgttgactcc ctatgcttcg
      301 ttttttgaat tgaaagaaaa gggataaaat accgactccc agaaaagcag cgatattcag
      361 agaaataagg taaataaaaa aaatcattaa aatttcaaac atattgacac ctttctagtt
      421 ggatagaacc tttacagaaa aaaggcaaaa ggcgggaata atgtttcaca cgaaacatta
      481 ttcgcggatt tgtccatcgc cataaatgat atattttgtg gaagttaatt catttaaccc
      541 cattggacca cgggcatgca acttttgagt agagatacca atctctgcac caaaaccaaa
      601 taccgatccg tctgtaaaac gagtggaggc attgacatag acagccgccg cgtccacttc
      661 atttaagaaa cgttgactag ccgcataact atctgtcacg atcgtttctg aatgtttagt
      721 attatgccga ttgatatgtg caattgcttc atccaaagaa tcgaccactt tgacagcaag
      781 gatataatct agatattcag tatcccaatc tgtgtcttct gctaaagcag ccgtctctag
      841 atattctaac gcacgagcat ccgcacgtaa agagaccccg tgttctacca gttctttttc
      901 aatagctggc aagaaaaaag gtgcgatctc agaatggatc agcaatgttt ctgccgcgtt
      961 acagacagat ggacgggaag cttttgcatt gacgatgatg ttcactgcca tagataactg
     1021 tgcttcttta tcgatatata cgtgattatt tcctgtacct gtttcaatga taggtaccgt
     1081 tgcctgttct ttgactcgtt ggattaattt tgctccgcct cgaggaatca gcacatctaa
     1141 gtattctgtc aatcgcatca actgtcctgc agtttcatga gaagtatcat cgacaaactg
     1201 gatggcataa ggagattcgc cagcactgac cagtacttgc tgcaataatt ggactaataa
     1261 ttgattcgag aagaatgctt ctttgccacc gcgaaggata acggcattcc ctgatttgaa
     1321 tgctagacta gctgcatctg tcgtgacatt tggacgagat tcgtaaatga tgccggtcac
     1381 gcctagtggc acgcgctttt tgccgattct caatccgtcg gtgttcgtcc acatctcatc
     1441 tacttttcca ataggatcgt ctaacgaagc aattttttcg atctctgtag ccatggcatt
     1501 gattcgctca ggtgtcagct gcaagcggtc ttgcatcgtt tcactgatat tgttttcgac
     1561 tgctttttct aagtctttat gatttgcttc aatgatcgct tgttgattct ttttgatggt
     1621 ttgtgccatt tgaacaagta gctcattttt gcggtttgta ggcataagtg ctagttgttg
     1681 cgcgctatct tttgcctgtt gtcctaattg catcaagtca gtcatttcaa gtcctcctta
     1741 aataaagtac ctacttcttt tcctgcaaga atatcaaaaa taattgccgg attttttcca
     1801 tttgctaaaa tcattgcgct gtttgcttca aatatcctag aagcggcttt taatttactc
     1861 tgcataccgc ctgttccaaa tgtgctacca gcaccacctg cttgtgccag aatcttttca
     1921 tcgattttat cgatatagcg atacatctga gcctcgggat ttgtagtcgg attatctgaa
     1981 taaaacccgt cgatatcaga aaggacgatc aaaaggtctg ccgcgacaag ttttgccatg
     2041 atggctgaca gctgatcatt atcgccaaat tttgtcagat gatctaattc atccactgct
     2101 acagtatcgt tttcgttcac gatagggatc gtgtccataa tcaaaagctg ttccaatgta
     2161 ttcctcacat ttttacgact ttcaggataa tctaccacgt ctcttgtcac gaggatctgt
     2221 gccgtctgtt gattatatac actgaatctt tgattataga tattcatcag ttcggcttga
     2281 ccaacagccg ccgcagcttg ctgttcagga atcaaagtcg gacgttctga caaatgtaat
     2341 ttatgcatac caacgcctac agctcctgat gagactaaga tcacttcctt tccccgattt
     2401 ctaagatcag aaaggacaaa agctaactga tcgattgccg caagattgat atttccattg
     2461 ggataaatca atgtacttgt tcctactttg acaataattc gttttgcatt tttaatttct
     2521 ttacgcatgt gacacctcaa tcaaatatcc actcattaat ttcgttctat tctacttgtt
     2581 ttgacgagta aagtcatgta aaaaatagtt tttttgtaca acttgcagtc gtttggaaaa
     2641 agaacgaatt aatggtttac tttaagatag cagaatttct tgaagaattt gtaaagaaag
     2701 tcttttacag cctcggatat gttagaatag gagtagt
//
LOCUS       DAYNVV010000132         2729 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.142, whole genome shotgun sequence.
ACCESSION   DAYNVV010000132 DAYNVV010000000
VERSION     DAYNVV010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.142"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(39..1415)
                     /locus_tag="ACGXWR_002862"
     CDS             complement(39..1415)
                     /locus_tag="ACGXWR_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFK0804326.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(1543..2631)
                     /locus_tag="ACGXWR_002863"
     CDS             complement(1543..2631)
                     /locus_tag="ACGXWR_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFK0804327.1"
                     /translation="MFWSLELLIIAALIMISSEINFIFEPIGTFFSTLFAPVLIAGFL
                     YYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQISSLASNMPDF
                     IKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSLGSIVGTIASA
                     TVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTLANYISGQAIE
                     CLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLVTVFNDPVKAL
                     LCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLGIFLGVPFYAI
                     CKTIISYIIKIVKEDKQNENKKKIATTS"
BASE COUNT          854 a          557 c          437 g          881 t
ORIGIN      
        1 ttattcaagc aacacgtctt tcataaccaa gtttccaatt atcttcttgg ctcgtcatct
       61 tcgaattctt ttctgaagta tcttcgttct tcttcaggtt ccgcttctgt ttcttccgga
      121 tcatgaaaaa tgacacggat tttaaggatt cgagaacctt ccatttcttc agaaaccagc
      181 gtaatattat cgacatcaaa cgataacttt tcgccttcat ccggaatcat gcctaatgct
      241 gtaatcaaat aaccagccat cgtatctaca tcactcatat gcagatcact gtcaaaagct
      301 tcattgaact catcaatcag catacgtcct tggatgatat attcgtgttc atcgattttt
      361 tcataaagat tctcaacttc atctgattca tcatcgattt ctccgacgat ttcttctaaa
      421 aggtcttcta gtgttgctaa cccaacgacg ccgccatatt catctaataa aatagccatc
      481 tgattctgcg tctttttcat ttcatataac agatcatcaa taaagaccgt ttcaggaacg
      541 aataaaggct cctgcatgat tttcttgata tctaaattat caaagccgaa tttatgggca
      601 gcttttagta aattctttgt atgaaggatt ccgactactt tatctttgtc ttcgttataa
      661 acagggattc ttgaatagtt ttcggataaa acttcattca cattttcttc cacagtgtcg
      721 ttgatatcaa tcataaatgc atccgttcgt gggaccatga cttctcgggc aactttcgta
      781 tcaagagaaa aaaccccttg gagcatttct aattcttcat tattcaatac gccttcgttt
      841 tcaagcatat aacgcatttc atctctggtc atttttgaat cttcatcatc aaaagtcatc
      901 ggcgtgatac gcgccaataa acttgtggaa gcagaaagca gccagacgaa gggcttagct
      961 actacaccaa tcaagcgtat cagccctgaa gtgaactttg cgacttcttc tgatttattt
     1021 aaagcaatac gtttagggta caattctcca aaaacaatcg atacataggt caaaatagcc
     1081 agcacaatga tatttgcaat attttttgcc gctgtgccgc cacctaatac cggagctaac
     1141 cgttccgata aagtattagc tagtgaagca ccagacaaaa tgttgaccaa agtgattcct
     1201 acttggattg tcgataggaa attatttgga ttctgcaata tttttaaaag cttttgagat
     1261 ttcacatctc cttcatcagc tttttgctcg attcgattct tattgatcga aacaacagca
     1321 atttcggaag ctgctaaaaa agcattgatc aatgtcaaaa cgatcaataa taaaatctgc
     1381 gctaacagcg actgactctc agggtcagca ttcataatcg cattctctcc ttataaaatt
     1441 aatttttagt ttacgataga aaaaaacgtg gcactatagc cacgttaaaa tggtatcaca
     1501 aagcaatttt ctttgcaata aaaacaagtg tactaaaact acctacgagg tcgtagcaat
     1561 tttcttcttg ttttcatttt gcttgtcttc tttgacgatt ttgattatat aggaaatgat
     1621 cgtcttgcag attgcgtaaa aaggaacacc taagaagata ccaagcaatc cggcaatatt
     1681 tccagctact agaagaacga taatgatcgt taatggatgg attttcagtg atttcccaat
     1741 tacattagga taaatgatat tcccatccaa ctgttggacg attagcacaa ccacacaaca
     1801 aagtaatgct tttaccggat cattgaagac tgttactaga aatgcaggtg ctagtcctag
     1861 ataaggtcct aaatatggaa ttaggtttgt caatcccgca atgaccccaa ataagaaagc
     1921 ataatccaca ccaattacca tatatcctaa aaatgtgaag gtaccaacga ataaacattc
     1981 gattgcttgt ccgctaatgt aattagccaa tgttttattc agttgcccca ataactccac
     2041 aatttggttt cttctttttt ctgggaaaaa ctgttggatg tttggcacta gtttttctcc
     2101 gtctttcaac atatagaaca agatgaatgg tgctgtaatg attactacgg ttgccgaagc
     2161 gatcgttcca acgatcgaac ctaaactatt ggatactcca ctaaggaatt gctgaatgat
     2221 tgtcccgtaa gaaatgtcta attgctcaaa atatttattg atatctactt ccttgaacaa
     2281 aggcaattcg gctacctctt ttaaccagct ttctacctgt ttgatgaaat caggcatatt
     2341 agatgccaat gaggaaattt gctgtactag acttgggatg acactaagta aaatccaaat
     2401 aattgctgca actaaaagga gcagcacaat tgcgacagcc catattcttt tgatttttgc
     2461 tttcatcaac agcttgacaa taggattcaa taaatagtaa agaaagcctg caatcagtac
     2521 aggtgcaaat aacgtggaaa aaaatgtccc gatcggttcg aaaataaagt ttatttctga
     2581 tgaaatcatg atcaatgcag ctatgatcaa taattcaagc gaccaaaaca ttagtttaga
     2641 ctgtctaagt ttttcaaaca atagatttcc tcctttcttt cttactagta tatattatat
     2701 tcgttaaaaa ttcttttatt cttttttta
//
LOCUS       DAYNVV010000133         2694 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.143, whole genome shotgun sequence.
ACCESSION   DAYNVV010000133 DAYNVV010000000
VERSION     DAYNVV010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.143"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..1444
                     /locus_tag="ACGXWR_002864"
     CDS             <1..1444
                     /locus_tag="ACGXWR_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF6020 family protein"
                     /protein_id="HFK0804328.1"
                     /translation="SFLFLQSIYLSMPKLETFFTAQNTQAFSSRKYFLFFTVFLVLCW
                     LPYLLALYPGVVLPDSLSSVAQSMGDVPISNHHPVLFTLLVKLFVHDLPTDTINHGVF
                     LFSIFQTLITASAISYSLCWLLKRNIHFFPVLISLCYFAFAPVFPIYALNMQKDTLFS
                     IACFLFSLAVFDFIFQREKPTILNQIYVIILALLTTYLRNNGIYVVTGTGLICGLIIL
                     KQKRYQAFFQVVLGYTVIAGLLIHPLMARYAIPTETAEQLGVPLQQISRTIVMDGDLS
                     KKDKAFMNQLLPIKDYEAYSPSLADSIKWHKNFNNEFLNTHKKEFLSLWARNLPSNIK
                     IYTDAYILETFGFWVPGTKNSYGFLDTRVNTNNYGMKQVDLIEHLTGLSGMKKIIDAR
                     DFFGSGTLLWLAIGSALLAIFKKKYRYLLLFLPGMLVFATIMIATPVAFSLRYVFVLA
                     LGLPVYILSPFLLDKREKMKTDIGDTHETI"
     gene            1431..2633
                     /locus_tag="ACGXWR_002865"
     CDS             1431..2633
                     /locus_tag="ACGXWR_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804329.1"
                     /translation="MKLFKKIFFAFVLLIASYCVLLTITFFIPQHSIESNAEKSLQMV
                     EKEGMYPSINQGNMLGTRLDNFTDHLMIRKTKADPELNSLENAMSMADYPRYWHGYQL
                     FLRPLLLGMSLGSIRMIYAAILFLLIGLTSYFLTKCSDIYLTTALLISLAIGNAATFF
                     FSMQFSNIWILTLLSVLLFLTKPQLSNTNQQLFLYFFVIGSLANFFDLLTTPVISWGI
                     PVIIIYYVTNKYLMDKRSSLSKQVGSFVFTGIFWGLGYGLTWVAKWILSSIILNKNIV
                     KDAINQILFRTEGNDKYPLHRLEMLKSNIRLMYPKVAILLLLITCLVFLYFAYRKRNS
                     WRPFQLLVLFVLAAVTPYIWYNILANHSQIHYWFTYRTQIITSFAILSAFAFLIPPEK
                     SKDELNYF"
BASE COUNT          771 a          481 c          465 g          977 t
ORIGIN      
        1 ttctttttta tttttacaat cgatttattt atcaatgcca aaactggaaa cattttttac
       61 tgctcaaaac acacaggctt tctcttcaag aaaatatttt ttattcttta ctgtcttttt
      121 agttctgtgt tggcttcctt atctgttggc attgtatcct ggagtggttt tgcctgattc
      181 gttaagttcg gtcgcccaat ctatgggtga tgttcctata agcaatcatc atccagtctt
      241 attcacctta ctggtcaagc tatttgttca tgatttacca actgatacga tcaatcacgg
      301 tgtattttta ttttcgattt ttcaaacatt gataacagct tcagcgataa gttattctct
      361 ttgctggctg ttaaaaagaa acatccattt ttttccggta ctcattagtt tatgctattt
      421 tgcatttgca ccggtttttc caatctacgc cttgaacatg caaaaagata ctttgttctc
      481 tatcgcttgc tttttatttt ccttagcggt ttttgacttt atttttcaac gagaaaagcc
      541 aacgattctc aatcagattt acgtaatcat ccttgcttta ctgaccacct atctaagaaa
      601 taatgggatt tatgtagtaa ccggcacagg tttgatttgc ggcttgatta ttttgaaaca
      661 aaaaaggtat caagcattct ttcaagtggt gctgggttat acagtgattg ctggactact
      721 catccacccg ttgatggctc gttatgctat tcctacagaa actgctgaac aattaggtgt
      781 tcctttgcag caaatttcta gaactattgt tatggatggt gacttgtcta agaaagataa
      841 agcattcatg aatcagctac tcccgataaa agattatgaa gcgtattctc ctagtcttgc
      901 agactcaatc aagtggcata aaaattttaa caatgagttt ttgaatacac ataaaaaaga
      961 atttctatca ctatgggcaa gaaatttacc aagtaatata aaaatctata cagatgctta
     1021 tattttagaa acgttcgggt tctgggtacc tggtacaaaa aatagttacg gctttttaga
     1081 tactcgtgta aacacgaata attatggtat gaagcaagta gatttgattg aacatcttac
     1141 tggattgtca ggaatgaaaa aaatcatcga tgctcgtgat ttctttggtt ccggcacatt
     1201 actgtggtta gctatcggca gtgcactttt agcaatcttt aagaaaaaat atcggtattt
     1261 actccttttt cttcccggta tgcttgtttt tgctactatt atgattgcta ctcctgtggc
     1321 ttttagttta cggtatgtgt ttgttttagc attaggtcta cctgtttata tcctctctcc
     1381 ttttttacta gataaaagag aaaaaatgaa aacagatata ggagatactc atgaaactat
     1441 ttaaaaagat attttttgct tttgttctct tgatcgctag ctattgcgta ctactgacaa
     1501 ttactttttt cattccgcag cactctattg aatcgaatgc agaaaaatct ctacagatgg
     1561 ttgaaaaaga aggaatgtat ccttctatca atcaaggaaa tatgctaggc actcggttag
     1621 ataattttac tgatcatttg atgatacgaa aaacaaaagc agatcctgaa ttgaactcct
     1681 tggagaacgc gatgtctatg gcggattatc cccgttattg gcatggttat cagctttttt
     1741 tacgaccttt actgctaggg atgagtttgg ggagtattcg aatgatttac gcagccattc
     1801 tttttctgct gattggattg acgagctact ttttaaccaa gtgtagcgac atctatttaa
     1861 cgacagcctt gttgatttcg cttgctatag gaaatgctgc aacctttttc ttcagtatgc
     1921 aattttcaaa tatttggatt ttgactttat tgtctgtatt actattttta acaaaaccac
     1981 aactctccaa caccaaccaa caattattct tgtatttctt tgtcattggt tctttagcta
     2041 acttttttga cttgttgaca acaccggtca tctcttgggg gatacctgtg atcattattt
     2101 attatgtaac aaataagtat ttaatggata aacgcagttc attgagcaaa caagtaggca
     2161 gttttgtttt taccggtatc ttttggggat taggctatgg tttgacatgg gtggctaaat
     2221 ggatcctatc atcgatcata ttgaacaaaa acattgtaaa agatgcaatc aaccaaatcc
     2281 tctttcgaac ggaaggaaac gacaaatacc cgttgcatcg attagagatg ctgaaaagca
     2341 atattagatt gatgtatcca aaagtagcaa tattattgct attgattact tgtcttgttt
     2401 ttctctattt tgcttatcgt aaacgaaata gctggcgtcc gttccaactt ctagttttgt
     2461 ttgttttagc tgctgtaacg ccgtatattt ggtacaatat tttagctaat cactcacaga
     2521 ttcattattg gtttacgtat cgtacgcaaa tcatcacaag ttttgctata cttagtgctt
     2581 tcgccttttt gatccctcct gagaaatcaa aagacgaact aaattacttt taagaatacc
     2641 gatgtactaa ttcattttta aacataaaaa ctccagctgt cagagatagc cgga
//
LOCUS       DAYNVV010000134         2685 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.144, whole genome shotgun sequence.
ACCESSION   DAYNVV010000134 DAYNVV010000000
VERSION     DAYNVV010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2685
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.144"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            154..417
                     /locus_tag="ACGXWR_002866"
     CDS             154..417
                     /locus_tag="ACGXWR_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFK0804330.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            417..689
                     /locus_tag="ACGXWR_002867"
     CDS             417..689
                     /locus_tag="ACGXWR_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFK0804331.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            766..1095
                     /locus_tag="ACGXWR_002868"
     CDS             766..1095
                     /locus_tag="ACGXWR_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFK0804332.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            1085..1372
                     /locus_tag="ACGXWR_002869"
     CDS             1085..1372
                     /locus_tag="ACGXWR_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFK0804333.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            1656..2513
                     /locus_tag="ACGXWR_002870"
     CDS             1656..2513
                     /locus_tag="ACGXWR_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFK0804334.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
BASE COUNT         1002 a          358 c          537 g          788 t
ORIGIN      
        1 ctctaggaaa aaattaacta gcaccacggg tataaaggaa acggataaca ctttacaatg
       61 ctgttttggt actccaattt aaacaaaaca atcgaattta cgtacttaat taagtacgtt
      121 agaatggaga tataaattag agggggagta gatatggcaa aaacagtctt aaatcctagc
      181 tcagcacgga aaaattttta taagttgttg aaagatgtaa atgagaatca tacggaaatt
      241 gaaatcatta gtgagcgcag tgaaaataat gcggtgctta ttggtttgga tgattggaaa
      301 gcaatcaaag aaacgctatt acttgagcaa ataggcactt tgggtgttgt tcgtaagcga
      361 gaaaaagatg atagtggatt tactaatgtt gatgaaattg attgggataa cttataatga
      421 ataactattc tgtgatgatt aaaaactcgg ctaaagctga tttaaagaaa atcaaacagt
      481 ctaatttgaa acctcaattt gagaaggtta ttcagacttt aaaggaagat ccctatctcc
      541 ctacccaatc atttgagaag ttaaaaccta cacatgaagg taggtattct agaagattga
      601 atagacaaca ccgggttgtt tataaggtag atgaagatga acacgtggtt gaaatttatt
      661 cagcaaggac gcattacgag tcacagtaat tacttgtaaa tacattatct cgtggtataa
      721 tgtatttact aagtaattac atactgttag aaatgaggga tttaaatgat tacaaaaaca
      781 agaaaacaag gcaattcaat catgttgaca gtacctaaag attttaatgt tcctaatgga
      841 gtcgaagttg aagcaaagtt ggtagagaat ggtattcttt atgaatttgt tgaaccacaa
      901 aaagaatttt atgattttag cgaagatatt ttgtctgata taattgcaga aggctacgat
      961 aaagatgaga ttcttgtaga atttaagaat agaaaaaaca aaatgcattc ttcctttaga
     1021 gatattgctg aagatacact tactaattct aaagtaatga ctaaagagga gttggcaaca
     1081 gaaattggct tatgaaatcg ttccttcaaa acatgtcatt aagtatttaa aaaagctaaa
     1141 agagaagcca ttgaaagaaa aatttttgaa tttaatttat gatgaaattg cgattgatcc
     1201 atataagggt gaacaaaaaa ctggggattt atcaggtatt tggtctagtg ggttcaaata
     1261 tgcgggcaca acatatagag tagcttacga gattatagaa aacaaggtta ttccagtatt
     1321 gttatgtgga acgcatgaaa acttttatga acagttgaaa aaattaatct agtgatttgt
     1381 tgtcgttctt aagaaggacg gcttcttttt atcgaaaatc tgattcgtct acatgactaa
     1441 agtcgcgagt attctctgct tctcgataaa ttaaataacg tcattacttt gaggaaagct
     1501 ataaatcaat atatttcagc ttttccttat ttatgtacta ccttttactt attaattata
     1561 aggtagtaca tatatatctt tttttggtag taactaaaaa taaatatgtt ataatagtat
     1621 caaatgaata ttgctaaaag aaaagaggta ggaacgtggt agcgaagaaa tatgtaatcg
     1681 gtaattttaa aggtggcgta ggtaaaagta cgtgcgcgca aatgttaggg tttgaatcag
     1741 cagttaatga aggaaaaaga accttgataa ttgacttgga tatgcaagga aatacttctg
     1801 atgtgatgaa cttaacgcat atgaacttca ctaacgaaga aggaggcgga gaaggtgaac
     1861 cgattgttta cgaaaatact gtgactgacg tgttgataaa caatcttcca cctaaagagg
     1921 ctgtctataa agtaatcaat aacctctata tacttccagc agacatgtcc tttgaaatgt
     1981 atgatgattg gatcaaagac caatataatg attcattatc ccaattcaaa tatatgaaag
     2041 aaaagctaga accattattt gatgagtttg acgtcatcta tttagatgtc ccaccttcta
     2101 tttctgtata tagtaaatcc gcgatgtaca ttgcggattg ggcaatcgtc gtcttacaga
     2161 cccaagtaaa atcgatgaga aatgcgatgc aatatcttga gtatatggac ttttttgtga
     2221 aagaatttga tacaaattta tatgttgctg gtgttattcc tttcatgttg gaaagcggtg
     2281 acgcagtaga tcaggaaatg tataaacaag cccaagagat ttatggggaa catttgatta
     2341 aaaatgttgt actcaaaaat gcgcgcttaa aacgatacga cggatcaggt attacgatgg
     2401 agaagacaaa gaaaggtctc ttaaaacaat gggatcgcaa aagccacgaa ttatttatca
     2461 gtattttgaa agaattggaa gaacacgaga attggtatgc ggaggtggag taattggctg
     2521 acatcaaagg acttgatatt tttgggaaca acaaaggact cgccaaaata aaaaaagaag
     2581 cagaagcaaa gaaaaagcag caagcaatta caccatctga aaataagcaa ttagaagtgc
     2641 accaagttca agaaataaaa acttcctcca atgttgaaag acaga
//
LOCUS       DAYNVV010000135         2439 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.146, whole genome shotgun sequence.
ACCESSION   DAYNVV010000135 DAYNVV010000000
VERSION     DAYNVV010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2439
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.146"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..382
                     /locus_tag="ACGXWR_002871"
     CDS             <1..382
                     /locus_tag="ACGXWR_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFK0804335.1"
                     /translation="RITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDNPYSQFLI
                     TVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKLYKEGNMT
                     VNQICEITNVSRASLYRKLSEVNN"
     gene            596..1291
                     /gene="vanR-A"
                     /locus_tag="ACGXWR_002872"
     CDS             596..1291
                     /gene="vanR-A"
                     /locus_tag="ACGXWR_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFK0804336.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1269..2423
                     /locus_tag="ACGXWR_002873"
     CDS             1269..2423
                     /locus_tag="ACGXWR_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="HFK0804337.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          840 a          437 c          515 g          647 t
ORIGIN      
        1 tcgaatcact cgtagtacac aagatctatt tgaattaatc gataacatac gagataaaaa
       61 ggcaagttta aaatcactaa aagatacatg gcttgattta tcagaagata atccatacag
      121 ccaattctta attactgtaa tggctggtgt taaccaatta gagcgagatc ttattcggat
      181 gagacaacgt gaagggattg aattggctaa gaaagaagga aagtttaaag gtcgattaaa
      241 gaagtatcat aaaaatcacg caggaatgaa ttatgcggta aagctatata aagaaggaaa
      301 tatgactgta aatcaaattt gtgaaattac taatgtatct agggcttcat tatacaggaa
      361 attatcagaa gtgaataatt agccattctg tattccgcta atgggcaata tttttaaaga
      421 agaaaaggaa actataaaat attaacagcc tcctagcgat gccgaaaagc cctttgataa
      481 aaaaagaatc atcatcttaa gaaattctta gtcatttatt atgtaaatgc ttataaattc
      541 ggccctataa tctgataaat tattaagggc aaacttatgt gaaagggtga taactatgag
      601 cgataaaata cttattgtgg atgatgaaca tgaaattgcc gatttggttg aattatactt
      661 aaaaaacgag aattatacgg ttttcaaata ctataccgcc aaagaagcat tggaatgtat
      721 agacaagtct gagattgacc ttgccatatt ggacatcatg cttcccggca caagcggcct
      781 tactatctgt caaaaaataa gggacaagca cacctatccg attatcatgc tgaccgggaa
      841 agatacagag gtagataaaa ttacagggtt aacaatcggc gcggatgatt atataacgaa
      901 gccctttcgc ccactggagt taattgctcg ggtaaaggcc cagttgcgcc gatacaaaaa
      961 attcagtgga gtaaaggagc agaacgaaaa tgttatcgtc cactccggcc ttgtcattaa
     1021 tgttaacacc catgagtgtt atctgaacga gaagcagtta tcccttactc ccaccgagtt
     1081 ttcaatactg cgaatcctct gtgaaaacaa ggggaatgtg gttagctccg agctgctatt
     1141 tcatgagata tggggcgacg aatatttcag caagagcaac aacaccatca ccgtgcatat
     1201 ccggcatttg cgcgaaaaaa tgaacgacac cattgataat ccgaaatata taaaaacggt
     1261 atggggggtt ggttataaaa ttgaaaaata aaaaaaacga ctattccaaa ctagaacgaa
     1321 aactttacat gtatatcgtt gcaattgttg tggtagcaat tgtattcgtg ttgtatattc
     1381 gttcaatgat ccgagggaaa cttggggatt ggatcttaag tattttggaa aacaaatatg
     1441 acttaaatca cctggacgcg atgaaattat atcaatattc catacggaac aatatagata
     1501 tctttattta tgtggcgatt gtcattagta ttcttattct atgtcgcgtc atgctttcaa
     1561 aattcgcaaa atactttgac gagataaata ccggcattga tgtacttatt cagaacgaag
     1621 ataaacaaat tgagctttct gcggaaatgg atgttatgga acaaaagctc aacacattaa
     1681 aacggactct ggaaaagcga gagcaggatg caaagctggc cgaacaaaga aaaaatgacg
     1741 ttgttatgta cttggcgcac gatattaaaa cgccccttac atccattatc ggttatttga
     1801 gcctgcttga cgaggctcca gacatgccgg tagatcaaaa ggcaaagtat gtgcatatca
     1861 cgttggacaa agcgtatcga ctcgaacagc taatcgacga gttttttgag attacacggt
     1921 ataacctaca aacgataacg ctaacaaaaa cgcacataga cctatactat atgctggtgc
     1981 agatgaccga tgaattttat cctcagcttt ccgcacatgg aaaacaggcg gttattcacg
     2041 cccccgagga tctgaccgtg tccggcgacc ctgataaact cgcgagagtc tttaacaaca
     2101 ttttgaaaaa cgccgctgca tacagtgagg ataacagcat cattgacatt accgcgggcc
     2161 tctccgggga tgtggtgtca atcgaattca agaacactgg aagcatccca aaagataagc
     2221 tagctgccat atttgaaaag ttctataggc tggacaatgc tcgttcttcc gatacgggtg
     2281 gcgcgggact tggattggcg attgcaaaag aaattattgt tcagcatgga gggcagattt
     2341 acgcggaaag caatgataac tatacgacgt ttagggtaga gcttccagcg atgccagact
     2401 tggttgataa aaggaggtcc taagagatgt atataattt
//
LOCUS       DAYNVV010000136         2421 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.147, whole genome shotgun sequence.
ACCESSION   DAYNVV010000136 DAYNVV010000000
VERSION     DAYNVV010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.147"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..288
                     /locus_tag="ACGXWR_002874"
     CDS             <1..288
                     /locus_tag="ACGXWR_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFK0804338.1"
                     /translation="ETQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINLYYSNK
                     NYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(801..874)
                     /locus_tag="ACGXWR_002875"
     tRNA            complement(801..874)
                     /locus_tag="ACGXWR_002875"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(838..840),aa:Ile,seq:cat)
     gene            complement(1063..2082)
                     /locus_tag="ACGXWR_002876"
     CDS             complement(1063..2082)
                     /locus_tag="ACGXWR_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFK0804339.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RSDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(2093..2299)
                     /locus_tag="ACGXWR_002877"
     CDS             complement(2093..2299)
                     /locus_tag="ACGXWR_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HFK0804340.1"
                     /translation="MNNRTFDILKWIAIVVIPALATFVGLVGKGVNWRYTDITVMIIT
                     GFGAFLGSILGVSNRTYKKISSDK"
BASE COUNT          739 a          466 c          405 g          811 t
ORIGIN      
        1 gagacacaat tatggtttaa atttgaccct tcgaatagat ttatcaaaga tttttataaa
       61 gtatggaatt cagaagtttt ctttttagca atcgaagata gcttattaat caatctctac
      121 tattctaata agaactattt caaaattcct gctgcgaaaa ctagaatgaa gaaggatgta
      181 tactttttgt ttgatatcgt gactgacgtg ccggacgcac gtagcgatca tcggcgttat
      241 gactatataa agtatacttt cgttgatcca gaaagataca aagattaaag taggctacct
      301 aaaaaggtag cccggaacga attttatcac catacttgtg aaaggagata ttttttaagt
      361 tagtattaag attgtgtaat atgatgatat ctatatttta tagtatcagt gctataaaat
      421 caaaaataag tcactaatta actaccactc caattgtaag ccttttttct cacttttttt
      481 caaaaatatg gtatgccttt taatagcttc aaatataaaa gagtttaaag cgtaacacac
      541 ttatggggaa gtggcttggg gtgcgcttta aactcttctt tattatcatc tcacaattta
      601 acccaaatgt ctttctattt aaaaatcaaa gtaaaacttt tcaaatatac agaaatataa
      661 ctatgtgaaa catcctttca ttaatccata aaaggataca taaaaaagcc actcatttga
      721 gtggcaatga agaaaagctt tagcttgtat aatactcttc aaaaaattct aacacagaac
      781 gattcaaatg gctacgttaa tgtaccctgt aggactcgaa cctacgaccg gacggttatg
      841 agccgtctgc tctgaccaac tgagctaagg gtactggttg ttgccacata aagccataaa
      901 caatcaacca gtagaatgtg tggcaacaaa cctgttatcg catagcttgg agtgtgacta
      961 ttatgggtga tagtgaagat atgcgataac atcactattt tatcgaatga tttttatagt
     1021 tgtcaatata gttatgtaat gctcctcaac gaggagctat ttttatcgtt taggaatatt
     1081 taaataccaa cgtttgtcat ggaaatcttg cgcaccgcct ttagtgtttc cctctggatc
     1141 attcgttgcc cgcatcatga catagacttt cttattaggg aagttacgca tgttaaaaga
     1201 tacatgatag ccaacatttc cagaagtatt ataagcttga tttacatctg atctataaat
     1261 tccatcagct cttactcgag ctaattcttt cccagtattg taatccataa tgaagatata
     1321 ctcgtattta tagttagcaa tgtgccatcc agctacatgc aaatttgcat tttcgatttc
     1381 tccaaactga tcaatgtggg cgtaattcgt tccatctgtc agtgtaggat tagctgcacc
     1441 agctcgtgtt ggatcaatga caggcttgtt ttcagaagtt gttggatttt catcggtaaa
     1501 tccatgagct aaatcatatg ctaatttttc tttacttacg cccatttcag aaagataacc
     1561 gtaaggatct gtatgatcgc cccagatgtt ttgtgttacc cataaatgcg atttgattcc
     1621 cggttggtta taaggagtgt ccaacgttaa tggaatacca tatttcattg ctgaatctct
     1681 agccaattca acgtatgcct tgtagttttt ctcaaacgtt gctttatcat gtgtgtgttg
     1741 taactcaatc tgcacaggac tgttggcatt agcatacgaa ccagcaccgt actgtacata
     1801 accaggttga ccgacttgat aaacaattcc gccgtctccc acaatataag cagtataagc
     1861 gctagtccat gaacgttgca tatactgcgc ttcattgcgt cctgttgctg tttcattagc
     1921 cgtttcatgc agtaaaatat actgattatt tgctacttgt gagctacctt catttgcgcc
     1981 caaattaaat tcattgttga tagtataggc aaatccgtta attggcaata aaaaaagagc
     2041 cgttaacagg ctcatcgcag taatagtaat tttctttttc atatctatcc tcctatttat
     2101 ctgatgaaat tttcttatac gttcgatttg atacacctaa aatactccct agaaatgctc
     2161 caaaacctgt aataatcatc accgttatat ctgtgtaccg ccagttaaca ccttttccga
     2221 caagaccgac aaaagtcgct aaagcgggga taactactat agcgatccat ttcaaaatat
     2281 caaaggttct attgttcata ctatccacct cccttcattg gttgggctac tttctttttc
     2341 aatcgcttgt tttcttctat caatatttct ctttctgaaa gcaaggcatc aatttgcccg
     2401 tccagttgtt caattttatc t
//
LOCUS       DAYNVV010000137         2395 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.148, whole genome shotgun sequence.
ACCESSION   DAYNVV010000137 DAYNVV010000000
VERSION     DAYNVV010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2395
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.148"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            316..570
                     /locus_tag="ACGXWR_002878"
     CDS             316..570
                     /locus_tag="ACGXWR_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFK0804341.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            571..888
                     /locus_tag="ACGXWR_002879"
     CDS             571..888
                     /locus_tag="ACGXWR_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFK0804342.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1447..2382
                     /locus_tag="ACGXWR_002880"
     CDS             1447..2382
                     /locus_tag="ACGXWR_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804343.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          861 a          338 c          453 g          743 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaatggatgt taacggaagt gtatggtgag tagttcactc gtattttgat atcgtttgta
      181 tatgttttca gcgttctaag tggcttattt tgtccaataa taatatggag tggaatccct
      241 taagaaacac cgttggcaat tgttgttata acatgttata atttattcat caaaaactaa
      301 aaggagtgtg ataacatggg aaaagaacta aaggttagaa agatcggcaa tagcgtggga
      361 gtgatccttc caagctctct tggattaaaa agcggagaca ttatccaagc caaacaagaa
      421 ggcaacttat tcatattaga tactactcaa atagcaaaag aacacgatcg caaattgatt
      481 gaagaaagtt tccaagactt tgagaaaggt ttaacagttt cagaaattga aatggtaaaa
      541 gctttcggaa aatacggctg gagtgaatag atgaaagagt acacgctagt ttattctaaa
      601 agttttcaga ccagccttga aacgataata gaagaatggg aaaatgagct tgctctttct
      661 ccagccagca taaaaagatt tgtaggtgcg atccagaagg ctttagaact aaccaaaaat
      721 tttccaacta tgcatgagga agtttccgaa atctatggaa tggatatccc aacatatcgg
      781 atcgtgatcg gcaaaagcta tgccttattt tatcggatcg accatgaaaa aaaagagata
      841 cttgtaggac gtattttcca atctaaacaa atgaaactag gcttttaaca ataattagga
      901 aaaagtcgct catcctctac aggtgggtga ttaatgccgc tcgatatggt tgttaaccgt
      961 cggttactcg aagattgata tataagactt agtacctttt tattttgctc catgttatgg
     1021 ccgaaggtct aaagatacaa tcattagtct agagaaaaat taagaaccgt aggaactacg
     1081 gggatcgctt ggtgaataag agacactgct attagtgaaa aaataagata tcaagtacgc
     1141 tctattccca aaaatttcgt gactttactc atgagaggtt caagtagtat atttttaatc
     1201 aaaattgatg taacttttaa taaatactac ctaaataagg tagtatttat ttttgtgttt
     1261 taaaagagga agtccaatat atctatggga aacttcttaa atattatgtt ggtacatgaa
     1321 aatatacatc cctgctagac tatttacaac attttacttt gtacgtattc ttgttttaaa
     1381 aggaatggga taaaatatag gtacaataac tatttgatgc taaatataat taatggagga
     1441 gagatagtga acatacttaa tgaaaaaaga tatgtatggt ttgctggtaa aaaatatatt
     1501 actactttca aaagattatc cgagttaatg cagcagactg ttaaaagtgc tatgcctgaa
     1561 ggatacaagt ttaattttgt tcaatcttca gtatctactg aaagtatcta tttttcaatt
     1621 ctttctgaga gtaggctttt tcattttaga ataagttctc atgtaaagaa aactgatgtt
     1681 gatatatata cgttccgtac aaataattat aaaaatttaa atgatttgag tagaagtatc
     1741 agtgaatatc tcaaggggaa tagctatctc aagattcgat tttcacatat attaatttta
     1801 ctaccatatt tgaatgagaa tttcacccta attcaagtag ataagtcttt cattgcctca
     1861 ggtaatcaag gaaatatgaa tattacaagt aacaaaacgt cacgtgtgct attggcgttg
     1921 atgggttacg gaattcttta tagagatgac caaaatggcc agattctaat aaatcgggct
     1981 gggcgttcat tattaatgaa atatagaaaa tttataccgg aagattttca aaacttacag
     2041 ttagaaaaca tgcgtttaga agatttattt agattagcag aagatgataa gtatagattt
     2101 gaagttttga aaattcaaaa gaatgaacta ttgaataagt tatatcctga gaatgcgata
     2161 aaagcacatt ttggtgatgc taatcatatg tatagttggt tcattcctaa aagatttaga
     2221 gggaaaatca atgctggaga tcaagtgaaa gtactcaatc gaaatagtac agatgtcgta
     2281 atgataacag atatctatgt agaagatgaa gatataatca aatatatgaa gcctgtgata
     2341 aaacttgtta ataaaaataa aggaacccgt ggtgctagtt aattttttcc tagag
//
LOCUS       DAYNVV010000138         2301 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.149, whole genome shotgun sequence.
ACCESSION   DAYNVV010000138 DAYNVV010000000
VERSION     DAYNVV010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2301
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.149"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..258)
                     /locus_tag="ACGXWR_002881"
     CDS             complement(<1..258)
                     /locus_tag="ACGXWR_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HFK0804344.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LKQRDTVIIACVIWGIINGYTSQRATYRAVCSVLFPNGDFPS"
     gene            1046..2272
                     /locus_tag="ACGXWR_002882"
     CDS             1046..2272
                     /locus_tag="ACGXWR_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFK0804345.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFKEITGISSEKFQKTFPTRQLAIKA
                     ENEMKKKIAKVLREENANSLELKGQIKFKEFYKSKWLPRYELGQTTRSHKAPSDITII
                     NTKNLFRLHILPIFGEYAMSYLNANTEIISDELTKKSKEYANIKIIKCYVRSMFDIAE
                     VLNYIEFNRTTKIIQSITAPKKVALEEKRIREGKQALSSKELTDWLDAVRDDFNDQLL
                     SFHDYTLFMLTLYLGDRKSETYALQWKYIDFENQTVRLKYALDKHTKKKFTKGRKDTI
                     IQVPEIVMTLLQEWKSVQAEQLLKLKIKQTPDQYLFSYSKPSGEVNCPVHTDYLNYRI
                     NSIKKRHPHLVHLTPHKLRHTYATLARQGGADMNQISNALTHSGISTTKIYVNTPDLV
                     DKAVFEAFQRGLQKSN"
BASE COUNT          828 a          355 c          367 g          751 t
ORIGIN      
        1 actaggaaag tcaccattag gaaataagac ggaacaaacc gctctatacg tggctctttg
       61 gctagtatag ccattaatta tgccccatat aacacaagca ataatcactg tatcgcgttg
      121 cttcagttga tcagtatttc ttcggttttt aatcttatct ggtacacaat tgtggtatat
      181 gttagaaaca gttctcataa tttccttgaa tgttataaaa gtatctgtat aatgttcagt
      241 atattttgat gaacgcatat gtagtcctca tttcttggga gttttgagac tactatatgc
      301 gtttttttgt tgatttacca acatgtttag acattttcct ctaggaaaaa attaactagc
      361 accacgggta ttattttaaa tttttacata cctgtttatg aaaaactaaa taatctgtca
      421 aaaaaatatg attgttcatt tctaaatatg ttttccaatt ttaaaatctt ttttagcatt
      481 tttgtttcct tttcatatgg tttttcgttg ttaatagtga ctaggatgat attcctattt
      541 tgaccattga caattaaata taatttttga ataacgttcc ctgctattcg agctaagaat
      601 tcaagtacgc catgacctat ttagcgataa ctacttagag atttcttttt gttttgggaa
      661 gacaaaatgc catgacaata gcagtagata atgatacttc cgtaaggctc gccgtaaact
      721 ggggagaggt gaaattccta tgtgcttacc caagtcaatt caaaaatttt agttcattta
      781 taaggggatg attttattaa atcaatagtc tatctaaaca aaaaacaaac ctgtgagttt
      841 ttaggaattg ataacaatac tttagataaa tggattcgta tatataattt tcccgtaata
      901 aaaatagacg gtataattcg ctttgatgta gaagatatca aaggctttat ggatacgttc
      961 aaaaagattt gaattttact tttgactgca tatactaaaa gtagcgaaat atactgcctt
     1021 acttttttat taaggagtga ggaagttgcc tacgaagctt tcaaatggaa aatataaaac
     1081 taatttgaga tatccaaaaa aatttaaaga aattacaggt atcagttcag aaaaattcca
     1141 aaaaacattt ccaactaggc aattggctat taaagccgaa aatgaaatga aaaagaaaat
     1201 cgcaaaagtc ttaagagagg agaatgcaaa ttcattagag ctcaaaggtc aaataaaatt
     1261 caaggagttt tataaatcta aatggcttcc tagatatgag ttagggcaaa ctactagatc
     1321 ccataaagct ccaagcgata taaccatcat taatacaaag aatttatttc gattgcatat
     1381 tctgcctata tttggtgagt atgccatgag ctatcttaat gcaaataccg aaataatatc
     1441 agatgaactc acaaaaaagt cgaaggaata tgcaaacata aaaatcatta aatgctatgt
     1501 tcgttccatg tttgatattg cagaggttct aaattatatt gaatttaatc gtacaacaaa
     1561 aataattcaa agtattactg cacctaagaa agttgctctg gaagaaaaaa gaatacgaga
     1621 aggaaaacaa gctttatctt cgaaagaact cactgattgg ttagacgctg taagagatga
     1681 tttcaatgat caattacttt cctttcacga ttacactctt tttatgctta ctttatatct
     1741 tggggataga aagagtgaga cctatgcttt gcaatggaaa tacattgatt ttgaaaacca
     1801 aacagtccgt cttaaatatg ccttggataa acacacaaaa aagaaattta caaaaggtcg
     1861 aaaagatact attatccaag ttccggaaat tgtaatgaca ctattgcaag aatggaaatc
     1921 agtgcaagct gaacaactat tgaagttgaa aattaaacag acacctgacc aatatctttt
     1981 tagttactcc aaaccttctg gtgaagtaaa ttgtccagtc catactgatt acttaaatta
     2041 tcgaattaat tctataaaaa aaagacatcc ccatttggtt catttaactc ctcataaact
     2101 tcgacatact tacgcaactt tagctagaca aggtggggct gatatgaatc aaatttctaa
     2161 cgctttgaca cattcaggta tttcaactac aaaaatttat gtgaatacac ctgatttagt
     2221 tgataaagct gtgttcgaag cgtttcagcg aggattacaa aaatctaatt aatgtgttct
     2281 agaatgtgtt ctaaatataa a
//
LOCUS       DAYNVV010000139         2230 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.150, whole genome shotgun sequence.
ACCESSION   DAYNVV010000139 DAYNVV010000000
VERSION     DAYNVV010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.150"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..376
                     /locus_tag="ACGXWR_002883"
     CDS             <1..376
                     /locus_tag="ACGXWR_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFK0804346.1"
                     /translation="NVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFRR
                     FPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTDD
                     WQKVMAAEVIATYLDGDLVYKK"
     gene            424..1824
                     /locus_tag="ACGXWR_002884"
     CDS             424..1824
                     /locus_tag="ACGXWR_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFK0804347.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1857..2024
                     /locus_tag="ACGXWR_002885"
     CDS             1857..2024
                     /locus_tag="ACGXWR_002885"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804348.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAFTGSVAKF"
     gene            2078..>2230
                     /locus_tag="ACGXWR_002886"
     CDS             2078..>2230
                     /locus_tag="ACGXWR_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFK0804349.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVREILYDRGINVSH
                     TTIYRWV"
BASE COUNT          626 a          371 c          483 g          750 t
ORIGIN      
        1 aaatgtttcc acagaggact tctttaatta ttgtcgatta gaggaaagtg gtgtaacagt
       61 cactagcggt acagatttac cgctgtttat tactgatatt cctgaatcga ttataagagc
      121 agtattccgt cgttttcctg aaggagaaga agtctgggag aaagaaacaa gcttcacgac
      181 aaccgagctg ctgaaaagtt ttacaagcaa cagcttcaaa gtaaatggtt tatcggagta
      241 cggagaaata aaagtaggga aaagcgccag cttagctgtt ttcagcgagg acctctgtac
      301 tgatgactgg caaaaagtga tggctgcgga agttatcgct acctatcttg atggtgactt
      361 agtttacaag aaataatgct tttcgatata acgttataaa acgaattaaa gagaggttaa
      421 aaaatggaaa caatgaaaag aaaattcacc ttcccacata gttatacatt gatttttatc
      481 ttaattattt tggctgcaat tttaacttgg ataattccta gtggtcagtt tgagacagtt
      541 gttgaaaacg tcgcaggtat ggaaaaaaca acggttgttc cgggaaccta tcaccaaatc
      601 gataaggcag attatggaca aggtttttcc tctatactaa tggcaccagc tgaagggatt
      661 atttcagctg ttgaggttgt tgcttttgtt ctcatcgttg gtggtgcctt cgggattatc
      721 ctaaaaacgg gagccatcga tcgagggctg tttaccttag caaaagttct gggagacaag
      781 gggatcttag ttattccgat gtcgatgatt ctattcagct taggaggatc aacctttggc
      841 atgagcgagg aagtcattcc cttatttgcg gtgtttattt ctctgatgtt ttctcttggc
      901 tatgattcca tgactgcgat cttgattcta tttttaagta cacaagcggg atatgttggg
      961 tcgacgatta atcccttcaa cgttttaatc gcacagggag tagctggcgt ttacggaaat
     1021 cccctgcttt ggtttcggat gctatcctgg attgtcatta ctgggatttc aattgttttc
     1081 accatgcttt atgctagcag agtcaaaaag aatccactgt cctctattgt ttatgagagt
     1141 gatttaaagg ttaagcataa gtttcaaaat tttgacactg aaaaagagtt ttcaacacaa
     1201 gataaactaa ttatcgccgg ttttatcgta ggtttaggaa tcatgatttg gggtatcatt
     1261 tccaagggat ggtatatggt tgaaatttct gcactattct taggattagg tctttttgct
     1321 gggggcatcg ctagattttc tcaaaaggaa attgctgaag cttttgtcga aggctgttca
     1381 gatttcgcct atgctgctgt aatcattggg ctagctagag gagtcttggt aatcttggaa
     1441 ggtggaatga ttattgacac tattctaaac agcttggcta accttttagg tggtcttcca
     1501 aaattcctgt tcactacgat tctactcatt tctcaagtaa ttgtttcctt ttttgttcca
     1561 tcctcctcag gagctgcggc attaacgatg ccggttatgg caccattggg tgatctaatg
     1621 aatgtaagtc gtgatgttgt tgttctaagt aaccagtttg gaaatggttt aatgaatatt
     1681 atctccccaa ctagtggtgt attactggca ggattagcca tcgcagagat taatttctct
     1741 aaatggttta aggttggctt caaaatattt gccatcttaa cccttgtttc tgctgttttg
     1801 ttatacattg ctacactctt ttagtcttaa tcatccatta ataggaggca atagttatga
     1861 ttaaaataaa tcaattagca ggaatgaata tccactattt attttattct ctcaaagaat
     1921 ttttcgctta tcaacagaaa attggtattt cttctgttga actttgggga ggtgctccgc
     1981 attttttcat agatgctttt actggttctg ttgcaaagtt ttaaatctac tatcaaataa
     2041 ggtagaataa tagaaaaaga tagcaggagg aatgacgatg aatcatttta aaggaaagca
     2101 atttcagcag gatgtgatta ttgtagccgt gggctactat cttcgttata accttagcta
     2161 tcgtgaagtt cgagaaatct tatatgatcg tggcattaac gtttctcata cgacgattta
     2221 tcgttgggtg
//
LOCUS       DAYNVV010000140         2176 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.151, whole genome shotgun sequence.
ACCESSION   DAYNVV010000140 DAYNVV010000000
VERSION     DAYNVV010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2176
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.151"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..679
                     /locus_tag="ACGXWR_002887"
     CDS             <1..679
                     /locus_tag="ACGXWR_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804350.1"
                     /translation="VVYGVAYYLLSEPKQIAASNIFTAVMTLMCVMCFSIFSYLLVQF
                     IRQNLTMSKLFKSLLDLLILGSMLTTLTDRFEQSEKTVEGIKNFLTTIDQFINGYMYL
                     FEVGFILTLFGCVFIKLIKRSIEKEMVIDLIPTLSGYEYYVDFGKYEELIHTDIVHTS
                     IHEVTVKGIRSTLKDGQETKTIDRRKEVYNFYKVEASLRYGIGKLRLDGSNIQQNKPY
                     VLGKVVI"
     gene            723..992
                     /locus_tag="ACGXWR_002888"
     CDS             723..992
                     /locus_tag="ACGXWR_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804351.1"
                     /translation="MILLYRIVLIVGTELKILKKEQLFKVKEHHNQLLCIKTGTMNIQ
                     YRTEYLELTNQTDFLSIREQHKQEKLMATYSQLIDEWEQFKESKT"
     gene            1224..1520
                     /locus_tag="ACGXWR_002889"
     CDS             1224..1520
                     /locus_tag="ACGXWR_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804352.1"
                     /translation="MNVKIRDLDPKFISEIDRRCVELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQEKFDQLLEKFSEIQSYNTKILEEYVSQNNRIIEILIEQNRGSEL"
     gene            1522..1944
                     /locus_tag="ACGXWR_002890"
     CDS             1522..1944
                     /locus_tag="ACGXWR_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804353.1"
                     /translation="MAKVIDKHIYFHQTHIDVLDETISTHAEVKNYSEAVRFLCMNYD
                     PEVEKKVNSNQAKLNGMSKEISILTEMVSEFADLHLKDTGILIGKNSTVYQEAKERVE
                     GKIKSNQTKKYSPQLKKPVNESVHARVDPFDPTKILKR"
     gene            1963..>2176
                     /locus_tag="ACGXWR_002891"
     CDS             1963..>2176
                     /locus_tag="ACGXWR_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804354.1"
                     /translation="MTQSPSVILTCQFTLPNKKSFSTYIDYITREQALEEKERRTPEE
                     EQELQRIKNALEEFYIPEGETFSESKT"
BASE COUNT          820 a          296 c          422 g          638 t
ORIGIN      
        1 ggtggtctat ggggtggcct attacttgtt aagtgagcca aaacagatcg cggcgtcaaa
       61 tattttcacg gcagtaatga cattaatgtg tgtcatgtgc ttttctattt ttagttactt
      121 actcgtccaa tttatcaggc aaaatttaac aatgagtaaa cttttcaaaa gtttattgga
      181 cttacttatc ttaggcagta tgttaacgac tctaacagat cggttcgaac aatctgaaaa
      241 aacggtagag gggataaaga acttcttaac gacgattgat caatttataa atggatatat
      301 gtatttgttt gaagtaggct ttattctcac tttgtttggt tgtgtattta taaaactcat
      361 taaaagatca atcgaaaaag aaatggttat tgatctaatt ccgacgctga gcggctatga
      421 gtattacgtt gattttggaa agtatgagga gttgatccat acggatatcg ttcacacgag
      481 tatccatgaa gtaaccgtta agggcatcag atctacttta aaagatggac aggagacgaa
      541 aacaatcgac cgaagaaaag aggtctacaa tttttataaa gttgaagcaa gtctacgata
      601 tggcattggg aaattgaggt tagatgggag taatattcaa caaaacaaac catatgtttt
      661 aggaaaagtg gtgatttaga acttcctatg aaagatgaat aaataaggag aatcttttga
      721 aaatgattct tctttacaga attgtgctta tagttggcac ggagttaaaa atcttaaaga
      781 aggagcagtt attcaaagtg aaagaacatc ataatcagtt actatgtatt aaaacgggta
      841 cgatgaacat tcaataccga acagaatatt tagaattaac gaatcaaact gattttttgt
      901 cgattcgaga gcaacataag caagaaaaat taatggctac ttatagccaa ttgattgatg
      961 agtgggaaca attcaaggaa tctaaaacat aaaattccat ttaaacacct tattttttaa
     1021 agagcataag gaaacgtgac cccactttta aaaaaagtgg ttggataggc tgtgcctatc
     1081 acgtttctga aaaaaataaa tgaccccaaa ataccaatat ataggatagt acaaggatag
     1141 caaaggatag taaaaggata gaggtaggat agcgaaaagg ataggatcct tttcactatc
     1201 ctatattata ttggaggata tttatgaatg ttaaaattag agatttagat ccaaaattca
     1261 tttctgaaat tgatcgaaga tgcgttgaac taagtaatcg tacaggaaat aaatggagtc
     1321 gtaatgatta tttaaagcta ctcgttgaaa atgattttga tcgtcctttg atggaataca
     1381 aacaagaaaa gtttgaccag ttattagaaa agttttcaga aattcaaagt tataacacaa
     1441 agatattaga agaatatgtt agccaaaata atcgtattat agaaatcttg attgagcaaa
     1501 atagaggaag tgaactttga tatggcaaag gttatagaca aacacattta ctttcaccaa
     1561 acacatatcg atgtattgga tgaaactatt tctactcatg cagaggttaa aaactatagt
     1621 gaagctgttc gctttttatg tatgaactat gatccagaag tggagaaaaa agtaaattcc
     1681 aatcaagcaa agttgaatgg aatgagtaaa gaaatttcta ttttaaccga aatggtttca
     1741 gaatttgcgg atcttcattt gaaagataca ggaatattaa ttggtaaaaa ttcaactgtt
     1801 tatcaagaag caaaagaacg agtggaagga aaaattaaat ccaatcaaac aaaaaaatat
     1861 tcccctcagt tgaagaaacc tgtgaatgaa tctgttcatg ccagagtaga tccatttgat
     1921 ccaacgaaga ttctaaaaag ataaaaatga aggaggataa taatgactca atcgccttca
     1981 gttattctca cttgtcaatt tactttgccg aataaaaagt cattttctac ttatattgac
     2041 tatattacaa gggaacaggc tcttgaagaa aaggaacgac gtacgcccga agaagaacag
     2101 gaacttcaac gaatcaagaa tgctttagag gagttttata ttcctgaagg agaaactttt
     2161 tcggagagta agacgg
//
LOCUS       DAYNVV010000141         2059 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.152, whole genome shotgun sequence.
ACCESSION   DAYNVV010000141 DAYNVV010000000
VERSION     DAYNVV010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2059
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.152"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..244)
                     /locus_tag="ACGXWR_002892"
     CDS             complement(<1..244)
                     /locus_tag="ACGXWR_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFK0804355.1"
                     /translation="MEVIIMNVGFIGAGKVGCSFGKYFQEHKIQVTGFYSKSEDSSLA
                     ASNFTSSKQYLNLRELVDENDTIFITTPDGQIQEVWQ"
     gene            482..1651
                     /locus_tag="ACGXWR_002893"
     CDS             482..1651
                     /locus_tag="ACGXWR_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFK0804356.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
BASE COUNT          729 a          346 c          323 g          661 t
ORIGIN      
        1 cttgccatac ctcctgaatt tgaccatcag gagtcgtaat gaaaatagta tcattttcat
       61 ctactaattc tcttaagttt aaatattgtt tactagatgt aaaattcgaa gctgctaatg
      121 acgagtcttc gcttttacta taaaatcctg ttacttgtat tttatgttcc tggaaatact
      181 tcccgaatga acaacctacc ttgccggctc caataaaacc aacgttcata attatcacct
      241 ccataaagaa gtgagactac aagtcccatt cttacgatat gagcttaaaa ataaaaatta
      301 aatcaaatat acagtatgtt tttttcaaat atcatccata gttaatttat cataatatcc
      361 catattttaa aataaaagat agcgtaaaat attttgtgta aatagaaatt tagggtagaa
      421 aaaaaagtcc attctgtaaa attaaagtta ccacacagaa attttatagg aggactttct
      481 catgactaaa tttactatag aaattatgca aacactactc aataaagggg atttagatga
      541 attatttcag gatcatttag agcgagcgat taattcactt ctacaagcag agctaactgc
      601 ttttttagat tacgaaaaat atgatcgaaa tggattcaat tcaggaaatt cccgtaacgg
      661 gaattattca cgtacattta aaacagaata tggcgagttg aatttaacta ttcctagaga
      721 tcggaatggc gaattttctc aacaaacact accagcatat aagcgaacca atgattcatt
      781 agaaacgacc attatccaat tatttcaaaa aggcattact atggctgaaa tctccaaatt
      841 aattgaaaaa atgtatggtc accactatac gccacaaaca atctccaaca tgagtaaatt
      901 ggtggctgaa gatgttttag cttttaaaga aagaacgtta gaagccaatt attccgttat
      961 atttatggat gcgacgcata tccctgtgaa gcgacagact gtttcgaagg aagcagtgta
     1021 tattacgatt ggtattcgtt tggatggaac caaagaagtt cttgggttta ctattgcccc
     1081 aactgagtct gcttatattt ggaaagaagt tcttcaagat cttagaaaac gtgggttaga
     1141 agaagtttta ttagtagtga cagacggatt aagctgtatt gaagaaagta tccatagtgt
     1201 gtatccgaat gcccaatttc aacaatgttg tgtgcatgta tctagaaata tcgctcataa
     1261 agttcgtgtt cgaggtcgaa aagaaatttg tgaggatttc aaattggttt accaagcgaa
     1321 ttcaaaagaa gaggcattgg atcacatcga ctttatgact aggaaatgga aaaagcagta
     1381 tccaagagtc gtcaatttac tcttgaatcc tgccctatta accttttata atttccctca
     1441 cgccatcaga cgaacaattt attcgacgaa cctgattgaa ggctttaata agcagctaaa
     1501 acgatatact cgaagaaaag aacaattccc taatgaagaa tctctagaga gattcttcat
     1561 ttctcaattt aatcaatata accaaaaatt tttaggtaga attcacaagg gatttaaaga
     1621 aattcaggat acattagagt cgatgattta actgtaatta acagaatgga ttttccattt
     1681 acatataatt cttgacgcta ccataatcta aataaccatc atattcatct actacttata
     1741 taattgagtt ttattaaact ttttaagttt ctattctatc aaatatttaa acaatctctg
     1801 catccgaaaa gactacctcg tatagtttta ctaacaatat ttttattagc gtgttcaaat
     1861 cctgatttct tgtatcaatt attttctgtt cactttcaat aagaaaaaag tctttacttc
     1921 catggataat aataagggtt ctgttgcaaa gttttaaata aagaataaaa tcccttacgg
     1981 tatctatgat ttaagctggg attcccaata ataccttgat ttcagtacag accgaaaacc
     2041 cgaagagagt gccttcttt
//
LOCUS       DAYNVV010000142         2056 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.153, whole genome shotgun sequence.
ACCESSION   DAYNVV010000142 DAYNVV010000000
VERSION     DAYNVV010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.153"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            493..714
                     /locus_tag="ACGXWR_002894"
     CDS             493..714
                     /locus_tag="ACGXWR_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804357.1"
                     /translation="MRVIKSEKFTLAEIMTTSELAQELDYNQAYVLRLAKEHLTEGKE
                     YRSAGRRNYLFSPEALKKLEKVITTKEGE"
     gene            715..972
                     /locus_tag="ACGXWR_002895"
     CDS             715..972
                     /locus_tag="ACGXWR_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804358.1"
                     /translation="MPKETTINVEQLEKLLESYSNDFIELTGGKVEETTDLFDLLLTN
                     ILELNSEEQKEHKGKLIAPSYRKAAKSAVPTGFLTKQPYIF"
     gene            complement(1108..1710)
                     /locus_tag="ACGXWR_002896"
     CDS             complement(1108..1710)
                     /locus_tag="ACGXWR_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HFK0804359.1"
                     /translation="MTSRKTKDERTRNWTFVVYPESAPENWREFLDELHVPWVESPLH
                     DKDVNPDGELKKPHWHVLIMFSGKKTYDQIREITQKIRSPNPQKCANAKGMVRYFAHM
                     DNPEKFQYAKSDIIAHGGAEIASYLSVTSAERYELIREMMSFVDSKNITEIKDLIDYA
                     MSERFDDWFPLLCDNSAYIIGQYIKSNRHGGSVNSKINKG"
     gene            complement(1777..1932)
                     /locus_tag="ACGXWR_002897"
     CDS             complement(1777..1932)
                     /locus_tag="ACGXWR_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032993 - protein-DNA complex [Evidence
                     IEA];
                     GO_process: GO:0006276 - plasmid maintenance [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HFK0804360.1"
                     /translation="MISNEKKRVVVTLTKEVADNLDKIAKQMGLSKSGLITIWVNANG
                     KENEQKK"
BASE COUNT          678 a          464 c          313 g          601 t
ORIGIN      
        1 aaaaaaaaac gctgaaaccc ttgggagagt aaggctaaac agctatcgac caatgaccaa
       61 tgaccaataa ggggggtgtc gtagtccccc cctcctccgc ccaattcata aacaccaaaa
      121 ccaaaaaaca aacctcaggg ctccgccccg aaccccgacc tccttctacc gaaatatatg
      181 caggcgccac gcttactatt tcgttcagct atcggctttt gcaatctaac acgaccgttt
      241 cgctaccagt cgccttacag gctccattct cgcttctctt acgtgtttta acgattgcgc
      301 cgataactaa acgaaataga cgctaaatcg cttaaaacgc aaaatagacc ctttttagag
      361 cattgatttt ttctactagt catttcgata atataaaatt gaccacaaca cagaaaactt
      421 atattataag cttatgtcgt aagtccgacg tactcacgta atatagacgg acgttaaatg
      481 gaaggagcat aaatgagagt gataaaatca gaaaaattca ctttggccga aattatgacg
      541 accagcgaac ttgcacaaga acttgattac aaccaagctt acgttttgcg cttagcgaaa
      601 gaacatctga ctgaaggaaa agaatatcgc tctgccggta gaagaaacta tcttttcagc
      661 ccagaagccc ttaaaaaact agaaaaagtc ataaccacca aagaaggtga gtaaatgcct
      721 aaagaaacaa ctatcaacgt tgaacaacta gaaaaattgc tagaatcata ttccaatgat
      781 tttatcgaat tgaccggcgg aaaagtcgaa gaaaccaccg acctctttga cctacttctc
      841 acaaatattc tggaattaaa ctctgaagaa caaaaagagc ataagggaaa actgatagca
      901 ccttcctaca ggaaggcggc taagtcggct gtgccaactg gttttcttac aaaacaacct
      961 tatatttttt gatatcacaa aaaaatccat tttggaccta ttttcggtca taatatagta
     1021 cctacttttg gtcatagttt cgtccgtagt tttggtcata gtgactaaga ctttcacgca
     1081 caaaaaaaga gctgaaatta acagctctta tcctttattt atttttgaat ttacacttcc
     1141 accatgacga ttcgatttta tatattgccc gataatataa gctgaattat cacaaagaag
     1201 cggaaaccaa tcatcaaatc tttctgacat tgcatagtca attaaatctt tgatttcagt
     1261 gatattctta gaatcaacaa acgacatcat ctctctaatc aactcatatc gttctgcact
     1321 cgttactgac aaataactag caatttctgc accaccatga gcgataatat cacttttagc
     1381 atattgaaat ttttctggat tatccatatg agcaaaatat cgcaccatac cttttgcatt
     1441 agcacatttt tgcgggtttg gagaccgaat cttttgagtt atctcacgta tttgatcata
     1501 cgtcttttta ccgctaaaca ttatcaaaac atgccaatga ggctttttca attcaccgtc
     1561 aggattcaca tctttatcat gaagtggact ctcaacccaa ggaacatgta actcatctaa
     1621 aaactccctc caattttcag gagccgattc aggatagact acaaacgtcc aattccttgt
     1681 gcgttcatct ttagtttttc tactcgtcat gctataatca ccttaattga acaacagtct
     1741 aacagcaaaa gcagtgcgcc aacactaatg cttttgctat tttttttgct cattttcctt
     1801 tccgttagca ttaacccaaa ttgtaataag accagactta ctaagaccca tttgtttcgc
     1861 aattttatca agattatctg ccacttcctt agtaagcgtt acaacgactc tctttttttc
     1921 attactgatc ataattcgta tcctccaacg actttttctt aaaaaccata gtaacaaaaa
     1981 agtaactaag gtgcaacagt ttagatacta attagcgaat aataggcctt aaacccttgg
     2041 cattactgat tttgtc
//
LOCUS       DAYNVV010000143         1991 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.154, whole genome shotgun sequence.
ACCESSION   DAYNVV010000143 DAYNVV010000000
VERSION     DAYNVV010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.154"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            272..838
                     /gene="amaP"
                     /locus_tag="ACGXWR_002898"
     CDS             272..838
                     /gene="amaP"
                     /locus_tag="ACGXWR_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFK0804361.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            851..1039
                     /locus_tag="ACGXWR_002899"
     CDS             851..1039
                     /locus_tag="ACGXWR_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFK0804362.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1052..1609
                     /locus_tag="ACGXWR_002900"
     CDS             1052..1609
                     /locus_tag="ACGXWR_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFK0804363.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1641..1883
                     /locus_tag="ACGXWR_002901"
     CDS             1641..1883
                     /locus_tag="ACGXWR_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFK0804364.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
BASE COUNT          723 a          308 c          406 g          554 t
ORIGIN      
        1 ataaatagaa tcttgtaata ataactgagc ataatctttg caatttttaa tcttgaataa
       61 tatcctttaa gtatagccag caatcaaaag taaatagaga ataagtaagc aattgttatt
      121 tcagtatcag actggcaata aaacgccgtt atgatccagc aatgtttggt agcgctttat
      181 ttactgatgc tatgctaact gttcgctatc tatactgtga ttgtcggtag agttatttac
      241 agggtaaaaa taagtttata ggaggtggaa aatgaataag gggttaaaaa taatcggtgt
      301 tatcatgagt ttactgctac tttcagtatt tctagcgatt gcgttgatca atgcgccgta
      361 tattatgcct gaacaattgg aacgatttcg cttctttact ttaacgaatt actacatgca
      421 acaatatatt ttctgggcag ctgtagtatt tgccgttctt gctattatca tcttgctagt
      481 cgttcttttc tatccaaagt caagaggaac tttcgttatg aaacgggaag atggcaaact
      541 aacaatcgac aaaaaagcga tcgaagggtt ggtacgttcc catttacacg aagaagagtt
      601 cattcattca cctaaagtac ggatacgttc aacgaaaaat cgaatccata tccatgtcaa
      661 cggagacttg aaacgaactt cttcattagt agggaaaaca ggtgtattga tgcaagatat
      721 cgaagaagaa gtaactaaag tactcggaac aaaagaaacg gtcaaagtgg cagtcacata
      781 cagcggttat gaagaacaag aagatacaag agactacaag cactctcgag tggaatagga
      841 gggccaaata atgaaagaac tattttcagc atacaagctc cctattatct ttgggggtct
      901 tggactactg ctagctgttt tatggttaac gattggattt ttcaagacat tgttgatcat
      961 aatcatgaca gcaattggcg caggaatcgg tttttatttg aaacagtcag gaatagttga
     1021 tcaatttttt aaatcatagg aggaaacaaa gatggaaaac aaaaacatga atacaacaaa
     1081 tggatcagtt ttggcaaatg aaaaaggaga aaaccgcatg atgaatggtg aattgactta
     1141 tgaagacaaa gtcatccaaa aaatcatcgg ttatgcattg aaagatgtag atggtctatt
     1201 gacattagat ggcggatttt tctcaaatat ggctgaaaaa ttagtcaaca cagataacgt
     1261 aacagcaggt atcaatacag aagtaggtaa gaaacaagta gctgtggatc tagatgtgat
     1321 cgtagaatac ggtaaagaca tcgaagatat ttacaaccaa atcaaagaat tgatcagtac
     1381 tgaagtaaac aatatgacac atttagatgt tatcgaagtg aatgtgaatg ttgcagacat
     1441 caaaacacaa gaagaatacc aaaaagatca agaaacagta caagacaaag taacagaagc
     1501 agcaaaatcc acaggacaat ttgcttcacg ccaaacagat aaagcaaaat ctgctgtagg
     1561 caaaggtgca caaaaagtca aagaaaataa cgaaccacgt gtacaataag aagtaagaag
     1621 tcagttagga ggaatttaaa atgggattta tttgggcatt aatcgtcggc ggtatcattg
     1681 gagcaattgc aggagcaatc acgaataaag gatcatcaat ggggatcatc gcaaacatca
     1741 ttgctggttt agtaggttca gcaattggac aagctttact aggaacttgg ggaccaacaa
     1801 ttgcaggaat ggctatcatt ccatcattga tcggtgcaat cattttagta ttagtcgttt
     1861 cattctttgc acgtaaatta taagcaaatt gaagaaaaac ttatgttgaa atgaagaaca
     1921 aatttgagaa ccgtagcgac actcgctgcg gttctttttt atatatttta tatgaagtat
     1981 tctttattcc t
//
LOCUS       DAYNVV010000144         1596 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.155, whole genome shotgun sequence.
ACCESSION   DAYNVV010000144 DAYNVV010000000
VERSION     DAYNVV010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1596
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.155"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..1407
                     /locus_tag="ACGXWR_002902"
     rRNA            <1..1407
                     /locus_tag="ACGXWR_002902"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            1502..>1596
                     /gene="rrf"
                     /locus_tag="ACGXWR_002903"
     rRNA            1502..>1596
                     /gene="rrf"
                     /locus_tag="ACGXWR_002903"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          447 a          339 c          469 g          341 t
ORIGIN      
        1 ccaagcagta agtctgaaga ggagtcaaat gcttcttttc ttaaggacaa gctgtgatgg
       61 ggagggaaat aatagtaccg aagttcctga tgtcacactg ccgagaaaag cttctagtga
      121 gaaaacagcg gcccgtaccg caaaccgaca caggtagtcg aggagagaat cctaaggtga
      181 gcgagagaac tctcgttaag gaactcggca aaatgacccc gtaacttcgg gagaaggggt
      241 gctgatcata cgatcagccg cagtgaatag gcccaagcga ctgtttatca aaaacacagg
      301 tctctgcaaa atcgtaagat gaagtatagg ggctgacgcc tgcccggtgc tggaaggtta
      361 agaggagtgc ttagcgcaag cgaaggtacg aattgaagcc ccagtaaacg gcggccgtaa
      421 ctataacggt cctaaggtag cgaaattcct tgtcgggtaa gttccgaccc gcacgaaagg
      481 cgtaacgatt tgggcactgt ctcaacgaga gactcggtga aattttagta cctgtgaaga
      541 tgcaggttac ccgcgacagg acggaaagac cccatggagc tttactgtag tttgatattg
      601 agtgtctgta ccgcatgtac aggataggta ggagccgtag aaatcggaac gctagtttcg
      661 atggaggcgc tggtgggata ctacccctgc gttatggcca ctctaacccg caccactaat
      721 cgtggtggga gacagtgtca gatgggcagt ttgactgggg cggtcgcctc ctaaaaggta
      781 acggaggcgc ccaaaggttc cctcagaatg gttggaaatc attcgaagag tgtaaaggca
      841 gaagggagct tgactgcgag accaacaagt cgagcaggga cgaaagtcgg gcttagtgat
      901 ccggtggttc cgcatggaag ggccatcgct caacggataa aagctaccct ggggataaca
      961 ggcttatctc ccccaagagt ccacatcgac ggggaggttt ggcacctcga tgtcggctcg
     1021 tcgcatcctg gggctgtagt cggtcccaag ggttgggctg ttcgcccatt aaagcggcac
     1081 gcgagctggg ttcagaacgt cgtgagacag ttcggtccct atccgtcgcg ggcgttggaa
     1141 atttgagagg agctgtcctt agtacgagag gaccgggatg gacttaccgc tggtgtacca
     1201 gttgttctgc caagggcatt gctgggtagc tatgtaggga agggataaac gctgaaagca
     1261 tctaagtgtg aagcccacct caagatgaga tttcccattt ctttaagaaa gtaagatccc
     1321 tgagagatga tcaggtagat aggtcaggag tggaagtaca gtgatgtatg gagcggactg
     1381 atactaatcg atcgaggact taaccaatag gttaaaagaa aagaactcgg aaaaaaactt
     1441 atgtgacttc aaatccagtt ttgagtgaac aaaatttact caataaaaga taacaccaca
     1501 gtgtggtggc gatagcgaga aggatacacc tgtaaccatg ccgaacacag aagttaagct
     1561 tcttagcgcc gattgtagtg aggggttgcc ccttgt
//
LOCUS       DAYNVV010000145         1570 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.156, whole genome shotgun sequence.
ACCESSION   DAYNVV010000145 DAYNVV010000000
VERSION     DAYNVV010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.156"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            336..716
                     /locus_tag="ACGXWR_002904"
                     /pseudo
     CDS             336..716
                     /locus_tag="ACGXWR_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295591.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            716..1513
                     /locus_tag="ACGXWR_002905"
                     /pseudo
     CDS             716..1513
                     /locus_tag="ACGXWR_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
BASE COUNT          594 a          252 c          288 g          436 t
ORIGIN      
        1 ttcaatttgg cgttgctcat tttgatcaat cgacgaaact cgaatataag caattttcaa
       61 aatttttacc tacttcctca aactatttaa aatacactca aaatcaacac taattttttt
      121 atacactata aagctgtcat ttttctagat aaatggcata aattttcagc gctaagtgac
      181 aaaagcaact aatttttcat gatagatttt taaatatctc aatctatctc caaaattagt
      241 tgcttttgta gctatagttg actatgaata tgacaaataa ttagaaaaaa ctgtgccaat
      301 taaatatcaa aatgacaaat tgatgaatca aattcaaatt aaggggggca accctggaag
      361 tcttaaattt accctcaatg aatggtattg aagatgaaaa tttaaggcgt ttgattaata
      421 gccttgtcat tgaattgtac aagtatcaag cagaatcaga acgaaaaaaa attaaggaac
      481 gtcaggcaca aggaatcgaa attgctaaga aaaaaggcaa attcaaaggt cggcaactga
      541 aatttaaaaa aaatgatcca cgtttaaagc atgctttcga tttgtttttg aatggtttat
      601 ccgataaaga agttgaagaa caaactggga tcaatcgccg aacgtttaga aggtatcgag
      661 caagatataa cgtgacagta gatcaaagaa aaaacaatga aaagagggat agttaatgag
      721 tacggttatt ttagctgaaa aacaagccag gcattagcct acgcaagtgc tttaaaacaa
      781 agcaccaaaa aagacggtta ttttgagatc aaagacccac tatttacaga tgaaacgttt
      841 atcacctttg attttgggca tttagtggaa ttagcagaac caggtcatta tgacgaaaag
      901 tggcaaaatt ggaaacttga atctttgccg atttttcctg atcgatacga ttttgaagtt
      961 gcaaaagata agggaaagca gtttaaaatt gttgcagaac ttctcaaaaa ggcaaataca
     1021 attattgttg caacagatag cgacagagaa ggtgaaaata tcgcctggtc gattatccat
     1081 aaagcaaatg ccttttcaaa agataaaaca tttaaaagac tatggatcaa tagcttagaa
     1141 aaagatgtga tccgaagcgg ttttcaaaat ttgcaaccag gaatgaatta ctatcccttt
     1201 tatcaagaag cgcaaacacg ccaaattgcc gattggttga tcggcatgaa cgcaagccct
     1261 ttgtatacgt taaatttaca acagaagggc gtacaaggta cattttcact aggacgtgtt
     1321 caaacgccca ccttatacct tatttttcag cgccaggaag ctagtataaa agtaaaacaa
     1381 gggtcattta agggcgttct aagccccaca cagcgtttta aaacccaaga ggagcttttt
     1441 tgcttttgtt tcttctaaac aagctaaaat aggcaatcaa gaggggataa ttgctgatgt
     1501 tcaaaccaaa gagatggata ggctacaatt aactagacag aaaaattaag gtgtgtagac
     1561 tagaagaaaa
//
LOCUS       DAYNVV010000146         1466 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.158, whole genome shotgun sequence.
ACCESSION   DAYNVV010000146 DAYNVV010000000
VERSION     DAYNVV010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1466
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.158"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..300)
                     /locus_tag="ACGXWR_002906"
     CDS             complement(<1..300)
                     /locus_tag="ACGXWR_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
                     /protein_id="HFK0804365.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKY"
     gene            393..742
                     /locus_tag="ACGXWR_002907"
                     /pseudo
     CDS             393..742
                     /locus_tag="ACGXWR_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1014..1304)
                     /locus_tag="ACGXWR_002908"
     CDS             complement(1014..1304)
                     /locus_tag="ACGXWR_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804366.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT          469 a          288 c          205 g          504 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tataga
//
LOCUS       DAYNVV010000147         1456 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.159, whole genome shotgun sequence.
ACCESSION   DAYNVV010000147 DAYNVV010000000
VERSION     DAYNVV010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.159"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..1040
                     /locus_tag="ACGXWR_002909"
     CDS             <1..1040
                     /locus_tag="ACGXWR_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HFK0804367.1"
                     /translation="EINQKYDETLKNVYSSLIVSNIEETSSSEIKNKLSLLKLKEKEY
                     IIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGLLNKLTISNIDSTREKIIKIFDKI
                     NNLFKNDNAELRKGLLEFKLQELELHYSYLVKITEEKEQQKAIKEQMIEEEKVRREID
                     REKKRIDKEQRQFNSEISKLIAYMQKANADVEKELYANKIQELEEKLKELEVIRENVL
                     QRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEPMDRIKELSSASVPFEFDVHAMIF
                     SEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLDEIEKVVLENYNGTVTFTKLAKAE
                     QYRRSLELSKD"
     gene            1112..>1456
                     /locus_tag="ACGXWR_002910"
     CDS             1112..>1456
                     /locus_tag="ACGXWR_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804368.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQD"
BASE COUNT          640 a          169 c          227 g          420 t
ORIGIN      
        1 atgaaataaa tcaaaagtat gatgaaacat taaaaaatgt ctattcttca cttatcgttt
       61 caaatataga agaaacttca tcttctgaaa taaaaaataa gctttctttg ttaaaattaa
      121 aagaaaagga atatattatt gacgatgctg tttctgtccc tcttatttta aataaacgag
      181 agaaaaataa tttaaagaaa aaaatgctca ttccatttga ttcagaagtg aaaggattac
      241 tcaataaact aactatttct aatatagact cgactaggga aaaaatcata aaaatatttg
      301 ataaaattaa taatttattc aagaatgaca atgctgaatt aaggaagggt cttttagagt
      361 ttaaacttca agaactagaa cttcattact cttatttagt gaaaattacc gaagaaaaag
      421 aacaacaaaa agcaataaaa gaacagatga tagaagagga aaaagttcgt agagaaattg
      481 atcgtgaaaa gaaacgtatt gataaagaac aacgtcaatt caattctgaa atttccaaat
      541 taatcgcata tatgcaaaaa gctaatgcag atgtggaaaa agaattatat gcaaataaaa
      601 ttcaagaact ggaagaaaaa ttaaaagaat tagaagttat acgtgaaaat gtattacaaa
      661 gagaattaaa tactagagcc ggttatgtgt atgtaattag taatattggg tcttttggtg
      721 aagacatata taaaattggt atgactagaa gattagaacc tatggataga ataaaagaat
      781 tgagtagtgc atcggttcca tttgaatttg acgttcatgc gatgattttt tcagaggacg
      841 ctccgtcttt ggaaactaaa ttgcataatc attttagaaa acaagaagtt aataaaatta
      901 atcaaagaaa agaatttttc aaagtttcac tagacgaaat agagaaagtt gttttagaaa
      961 attataatgg aacagtaaca tttacaaaat tagctaaagc tgaacaatat agacgatctt
     1021 tagaattgtc aaaagattaa atatataaaa agccttcggg ctttttcttt taacaattaa
     1081 taggaacgta tattcgaaag gaatagaaat aatgtggtta gaaaaaataa atgacaaaaa
     1141 atttaagtac accgaacgtt atacggatcc cttaactgaa aaaaagagaa aagtgtccgt
     1201 tactttatct agcaattcac gccaagcttg gaatcaagct aacttacttt tgaatgaaaa
     1261 aatcgcagaa aaaataaaac gaaatgaaga attaccacta acttttggag aattaaaaac
     1321 taaatgggat gaaaaataca agccaactgt aaaagaaagt tcctatcgaa caactcaggt
     1381 ttatctatca ttaatttcaa aatatataaa agatgatgta cttgtaaaaa acgttaatag
     1441 taatcttata caagat
//
LOCUS       DAYNVV010000148         1451 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.160, whole genome shotgun sequence.
ACCESSION   DAYNVV010000148 DAYNVV010000000
VERSION     DAYNVV010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1451
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.160"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            105..1406
                     /locus_tag="ACGXWR_002911"
     CDS             105..1406
                     /locus_tag="ACGXWR_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFK0804369.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          476 a          293 c          264 g          418 t
ORIGIN      
        1 gatagaaaat cattctatcg gtcccttttg agcatgaaaa aacaaaacat acagaagctc
       61 cgttagaatt gaatcaccac aacacaatca aaggagcgtt ctgtatgcct gatcttcatc
      121 atatcaaact actacttgga atcaaagata aaaacatttt catcacaaat gtggaatcga
      181 agagcattaa gaatatcaag agtcttgttg tttctgcgac gttaagtaaa gaaattcgtc
      241 gctgtccttt gtgtaaacag atgaatcatg aaggcatgat cgttaagaac ggaaagaaaa
      301 aatcgctcat tcaacttaat aaatgtgcga accaactgac ttatcttgct ttagcgaaac
      361 aacgctacca ctgtcgtggc tgccacacct attttacggc gaatacctac attgtcgata
      421 gaaactgctt tatcgctaaa caagtgcgct ataaaatttt agaagagcta actgaaaaac
      481 aagcaatgac gacaattgct aagcattgcg gcgtttcttg gtcgaccgtt tctcggacac
      541 tcgcttctct gatccccatg acaaaagtaa aaagaaattg gttaccgcgt tgtttattaa
      601 tggatgaatt tcgttcactg aaaaatcaag tcggtcccta ctccttttct tgtatggatg
      661 gcgatactgg aaaattactg gatattcttc cttcacggaa gaaaaaggct ctcgtttctt
      721 attttatgca atttgaacga cgcgcacgat tgaaggtaaa ggtcatcgtg acggacatga
      781 atgtttctta tgcctctctg ataaaggaat gttttccaaa ggcaaaactc gttgtggatc
      841 gttttcacat tgtcaaacat ctcattcgta aatttgagga tattcgcgta cgaatcatga
      901 aaagctttga tcgaaacgat ccaacacaag ccaaatatta tcgacaatta aaggcgttgt
      961 ctcggcttct gatcaaacga caggacaagc ttgtttatga caaatggacc aaatggcgca
     1021 attttggttg ggcgtatctc accgaaagtg aagtggtgga tcgtctgctt tcgatctctg
     1081 acgaattacg aatcgcctat ttttactatc aagaaattct tcaagcgttt cacgacaaag
     1141 aggcggacac tttctttaaa cttgtaagaa cgatgcccaa ttccgttcca aaagaactgc
     1201 attctataaa aaaagctttt ataaactatg aatccggcat tcgtttagcc ctcgaattgc
     1261 cttattcaaa tgccaaaata gaaaatctgc atacccacat caaagcattg aaacgagtcg
     1321 cttatggctt tcgaagcttt cggaaaatga agaccagaat tttcttacta aataatctga
     1381 ttacctatga atcaaaaaac atctaaagta gaaaaggaat tctaccttag atgttcttat
     1441 ctcactctat c
//
LOCUS       DAYNVV010000149         1445 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.161, whole genome shotgun sequence.
ACCESSION   DAYNVV010000149 DAYNVV010000000
VERSION     DAYNVV010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1445
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.161"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            1..241
                     /locus_tag="ACGXWR_002912"
                     /pseudo
     CDS             1..241
                     /locus_tag="ACGXWR_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612146.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
     gene            347..>1445
                     /locus_tag="ACGXWR_002913"
     CDS             347..>1445
                     /locus_tag="ACGXWR_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
                     /protein_id="HFK0804370.1"
                     /translation="MQGVIAMMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFE
                     FIYPIVEATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYS
                     FEEKIPHFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNLYLDSTHIKANA
                     NKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPE
                     SGYYVKGEREKQFAYSAHTSCDDNGFILSTIITPGNIHDSQVAFQLVKQSKRLFPEIN
                     CVVADAGYKTPKFVHFLTHLNLRPCLPYSRPKGKKGLLSKNEFLYDEYFDCYICPQDQ
                     MLAFSTVTREGYREYKSNPKECVNCPLLNQCT"
BASE COUNT          465 a          270 c          282 g          428 t
ORIGIN      
        1 ctatactgtt gcttatttta aagtacatca ttctacttgc aatgaagcca aaacgacaaa
       61 cgtattgaat cgtaaattct taagagacaa cccattagaa gcgatcgtaa cagacttgac
      121 ttatgtacga gtcgggaaaa aatggaatta tgtctgtttc attttggatc tgttcaatcg
      181 agaaattctc ggctattctt gtggagaaca taaagatgcc gttctagtaa aaaaagcatt
      241 tagccgtatc aaacaacctc tgacagaggt tgacagactg tagacaaagt ccattttatg
      301 gatgatgtct acagtctttt cttttataat agatttatga aaacgaatgc aaggagtgat
      361 agctatgatg tctaaaaaca atacgaatgg tagaaatcaa tttgcgatgc ttacgattga
      421 tgatctagtt cctcaagatc atctcgttcg aaagattgat gccgcgcttg attttgaatt
      481 tatttatcca atcgtcgaag ccacttactc cgatttaggt cgcccaagta tcgatccagt
      541 gattctgatc aaattggtgt ttattcagta tttattcggt atccgttcca tgcgacaaac
      601 cattaaggaa gtcgatacca atgtcgctta ccgctggttt ttaggctact ccttcgagga
      661 gaaaatcccc catttctcaa cttttggaaa gaattatgtt cgccgattta gagaaacgac
      721 ggtgtttgag gatatttttg cctatatttt agaacaagca gttaaagcag gttttgtaac
      781 agaggataat ttgtatctgg attctaccca catcaaagct aacgccaata aacataagtt
      841 tacgaaagaa atgacccatg atgaagcgaa agcctatcag gatgaattag aagatgagat
      901 caatcgtcaa cgaatagagg ctggaaaacg cccttttact ttggacttag aaaaggaagt
      961 gaagctgaaa gaaagaaaaa taagtaaagc tgatccggaa agcggctact acgtcaaagg
     1021 cgaacgagaa aaacaatttg cttattctgc ccatacttca tgcgacgaca atggatttat
     1081 tcttagcaca atcatcactc ctggaaatat tcatgacagt caagtcgcct ttcagctcgt
     1141 caaacaatcg aagagacttt ttcctgaaat caattgtgtt gtcgctgatg ctgggtataa
     1201 gacacctaag tttgttcact ttttgactca tttgaacctt cgaccttgtt tgccttattc
     1261 aaggcccaaa gggaaaaagg ggctattatc aaaaaatgag tttctctatg acgagtattt
     1321 tgattgttat atttgtccgc aagatcaaat gctcgctttt tcaacggtta ctcgagaagg
     1381 gtaccgagaa tacaaatcca atccaaaaga atgtgtgaac tgtcctctgc taaaccaatg
     1441 tacca
//
LOCUS       DAYNVV010000150         1424 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.162, whole genome shotgun sequence.
ACCESSION   DAYNVV010000150 DAYNVV010000000
VERSION     DAYNVV010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.162"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            4..1424
                     /locus_tag="ACGXWR_002914"
                     /pseudo
     CDS             4..1424
                     /locus_tag="ACGXWR_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          590 a          223 c          318 g          293 t
ORIGIN      
        1 gtcatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ttagtacgat tgcaaaatga attaaacgaa caaattgaaa agatgtttga acaccagaga
      121 aagaccaacg gtcaaccaat gaacgataag agaaatgggc attcttggtt taggcaacaa
      181 gagcgaatcg aaaataaagt gcatagtctg agagaagaga tcaagcaaca agaaaaacaa
      241 gtagaaaaac ttgaaagaca agaagagata aaggaaatgg gctataacaa gtacggcgga
      301 ctggatatga cgatcgagaa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcga ctttttcagc cgctacgatc cgaaaatacc aacggaaatt ggaaacatta
      421 gaacagctga aagaaagatc ggaaaaagga aaagaaaacc ttcttcctga agtacaagca
      481 atcattgaca gcggacgagt gacgcaatgg aaaaaaatcc gaccatttat tttctgaaag
      541 gctatcgaaa agtcgcttta gaactgaatg aaaacgggga atttgaggaa tctaaaaaat
      601 accaagccac gtcggaagag gaaaaagcag ctgttcgtga attacttgaa gaggctgtac
      661 caactgattt tttgaaggag aaagaaaacg atcattttta tcgagtagaa ttcaacgaaa
      721 atgatccaga aaaaggattg aaaagttatg gtggggagat cgtaacattc gaattgatcg
      781 atcaactcaa aacgttggat aaccaatacg ccgcagaagc aggttattat aaattctatt
      841 ttgaagaagt gaagaacgga gaagtagtcg atcagatccg aatggatcta ggggatggcg
      901 tcaacagtaa tcaacccatc tatttagagt tagcaaaatt gtgcgaacaa gtacctgaga
      961 aggaacaaaa acaatcggtc aaaaatgaac ctgtttcgaa agaacaaatg cagtcgaaag
     1021 aaacaaaaac aaaacaaaag ggctatcaaa aacgaacggc agaagagatt aaacaagaag
     1081 ttaaatccct ttcgcaacag gcactggatg cggtgaaaaa gcatactcat tctcctgaag
     1141 acgtcaaaga acttttgaac tttatgtctc gttttccaga acgatccttt agaaatcaat
     1201 tattgattga ggaacaattt ccaggtgcaa cggcttgttt aggtcgtgcc gcgttgaaaa
     1261 aagaaggaat ctatatcaaa aaaggggaac aagggaacaa gatctttgtc agaaaaacgg
     1321 tcaaaggatt ttatgagaaa ggacgtggct ttgttcgaga aatagaagct acaccagaag
     1381 ataaaaaacg aatcgaaagt ggtcaaatcg aagtgatcaa aaaa
//
LOCUS       DAYNVV010000151         1424 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.163, whole genome shotgun sequence.
ACCESSION   DAYNVV010000151 DAYNVV010000000
VERSION     DAYNVV010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.163"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(150..1337)
                     /locus_tag="ACGXWR_002915"
     CDS             complement(150..1337)
                     /locus_tag="ACGXWR_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HFK0804371.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DAYNVV010000152         1422 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.164, whole genome shotgun sequence.
ACCESSION   DAYNVV010000152 DAYNVV010000000
VERSION     DAYNVV010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1422
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.164"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="ACGXWR_002916"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="ACGXWR_002916"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFK0804372.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTITPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          497 a          184 c          236 g          505 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtca ctattactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctggactaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta acttattgct tttgcaaaat ttatttacct gttttctgga tcaacgatag
     1141 tgtatattat gctatccttg tttggatttt aggacgttta aagaggcact tttttacata
     1201 acttaatcca tagacctttt aagcatgctg tgagataata ataaagaaga gtttaaagcg
     1261 caccccaaac cacttcccca taagtgtatt acgctttaaa ctcttttata tttgaattca
     1321 ctaagaagca taccatattt ttgaaaaaaa gtgagaaaaa aggcttataa ttaggattta
     1381 gagtaattaa ttagatgttt attttatagg actgatacta ta
//
LOCUS       DAYNVV010000153         1409 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.165, whole genome shotgun sequence.
ACCESSION   DAYNVV010000153 DAYNVV010000000
VERSION     DAYNVV010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1409
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.165"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            84..1376
                     /locus_tag="ACGXWR_002917"
     CDS             84..1376
                     /locus_tag="ACGXWR_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1251 family transposase"
                     /protein_id="HFK0804373.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
BASE COUNT          459 a          287 c          256 g          407 t
ORIGIN      
        1 tttattttcc aaaacatata gaaaagacac cttgaaatcc tttagaatta atttggcgaa
       61 ccaacccaaa aggaggaatc aagatgtctt acactcacct tatcaaagaa acattagata
      121 ttctagactt atcagttact tttaacgaaa attgtctcac aaaagaaaaa tacaaagggc
      181 aaatctgtca tatttatcgt ggaaacttga tttatacagc ccaagaatgc atccactgta
      241 aacaccagat tgcttcagat attgtgcgtt ggggtacaac aaccgtccgg ttgttaatga
      301 acgatgtttc tgaataccgt acctacctcg aattgaaaaa gcaacgcttc aaatgcaaag
      361 cttgtcagcg gacctttgtc gcagatactt ctgttgcgaa aaaacattgt ttcatcagtg
      421 agaaagtccg ctggtctgtc gtgactcgtc tgaaaaaaaa tacctcaatg acagagatcg
      481 ccgctcagaa aaatctatcg gtctcttctg tttaccgtat tatgaagcga ttttatcgtc
      541 cgttgaatcc ttttcggaca ccgttaccta aggtactttg ttttgatgaa ttcaaatcag
      601 ttcggggtgt ttcaggtgct atgagtttca tcatgatgga tggacaaaca cagcgcttat
      661 tggacattgt cgagaaccga caactgcctt ttttaaaacg ttattttagt catttttcac
      721 gagaaattcg tgaagcggtc gaatggatcg tgattgatat gtacgctcct tatgtatcgc
      781 tcgttaaaaa gctgtttcca aaagcacagc tgattattga ccggtttcac atcgtccaac
      841 atattggtcg tacctttcgc aatcatcgaa tcaaagaaac gaaccaacta ttaaaaagca
      901 aagaacaaaa acactatcaa ttaggtaagc aattaaaaag atactggaaa cttcttcaaa
      961 aagatgaacg caagcttgat tatactcgac gcctttggcg acctggcttc aaagctcatt
     1021 taacagagac cgatattgtg gatcgcttac tgaaagggag ccctgctttg cgtgtaggct
     1081 atcagttata tcaagacttt ctttacgctg taaaggaacg agactacgta tcgtttgaag
     1141 aactacttac caataatatc atgcttcccg aaggctatca gacgaccttg agaacgttcc
     1201 agaaatttct gccacaaatc aaaaatgctt tacaacaaag ttattcaaat ggcccacttg
     1261 aatgtctgaa caaccatatc aaagtgttaa aacgaaatgc atatggcttt cgtagctttt
     1321 ataatttcaa attgcgcatc atgattcgtc atggcaacgc attgattttc aactaaaaaa
     1381 gatcaagagg aactgatcca cttgatctc
//
LOCUS       DAYNVV010000154         1371 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.166, whole genome shotgun sequence.
ACCESSION   DAYNVV010000154 DAYNVV010000000
VERSION     DAYNVV010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1371
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.166"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(156..1297)
                     /locus_tag="ACGXWR_002918"
     CDS             complement(join(156..1069,1069..1297))
                     /locus_tag="ACGXWR_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFK0804374.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
BASE COUNT          341 a          271 c          287 g          472 t
ORIGIN      
        1 gacacgattt gtgagaattt tttcgagatt ccagcgggtg agtatctcat cgtttcgacc
       61 agcggtcaaa ccaaaaccgt ttgaccgctg atcgaagcga tgaagttgaa accctgtgga
      121 aatctcgcca aaaaaatgta agtggtagct aggaactaag cttgcaatgc caactcctcc
      181 atctgatttg gtgttaaata gttgatacta ctatggattc gcttgcgatt gtaaaatcct
      241 tcaatgtatt gaaataacgc taaataagca gcttcaaagt tttcatacgc ttttgatgga
      301 tagacttctt cttttttgag tgaggcgtga aacgattcga taccggcatt atcgtaggga
      361 cagcccttac gactgaagga gtgccgaatg ttcaattcat tcagctttgc ctcataggct
      421 tcgctagtgt actgagaacc caaatctgag tggatgatca agttctcgga gggtgtttgg
      481 tttaagagcg cattgtcaag ggtttcgata accaattctt tcgtcatctg cttgccaaac
      541 ttccaaccga tgactttctt tgtgtggagg tcttgaatag tggagaggta ggtccagcca
      601 tcttttaggg tatgaatata ggtaatatct gtcacccatt tttgattgat cgacgtagtg
      661 gtaaaatctt ggtttaacag gtttttacgt ccttcacttt taactttcgc ttgtttgcca
      721 ggcttgtact tcttgagggt gactgaacgc aagcctaatt ttctcatcag tatttgtact
      781 ttctttaagg acaaggtctc gccacggcca acaagaatct tatgaatttt aggcgcacca
      841 tagataccct tgttttcaaa gtagattcct gaaatcaagc ggtttaagcg tttgttttct
      901 gattggcgct tggaaggttt ctttttcttc cagtcatagt agctggattt cggtgcttcc
      961 aaaacggtac acatttgttt tacgtcatga tcatgaacat ttgattgaat aaattcgaag
     1021 acatcactca tttttacttt tgagcgaata tggttaaagc cttttttagg atagtgtttt
     1081 cctcctgcat gcgggccatt tcctttttca tcgctaggat ttctgcctca gtcatgccgg
     1141 ttgctacatt ctttgtatga agcttcttcc aacgataaat cgtttgtgta gcgataccat
     1201 attgcgctgc cagttcttcg accgattggc cagactggtt taaatctaag atcatcttct
     1261 taaagtcttc atcaaatttt ttcttggctt ttgccatcgt ggacacgtcc ttttcttagt
     1321 agttagattc tacggttctg ttgcaaagtt ttaaatctac tatcaaataa g
//
LOCUS       DAYNVV010000155         1340 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.167, whole genome shotgun sequence.
ACCESSION   DAYNVV010000155 DAYNVV010000000
VERSION     DAYNVV010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1340
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.167"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            72..>1340
                     /locus_tag="ACGXWR_002919"
     CDS             72..>1340
                     /locus_tag="ACGXWR_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HFK0804375.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFL"
BASE COUNT          455 a          260 c          255 g          370 t
ORIGIN      
        1 ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca actgagagga
       61 cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag aaagatttga
      121 tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc gtcgatgctg
      181 ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta gatggaaacg
      241 ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt gaacaataca
      301 atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa aactgtcgca
      361 cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca aatcatgtta
      421 gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt gcgaaaagct
      481 gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc tatttaccaa
      541 agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt tcgcatgctt
      601 ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa ttaatagatg
      661 ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt accaatccag
      721 aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc accaaacgtg
      781 ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac atgaatcaag
      841 cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga cagaaaagcc
      901 aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca aacatcaacc
      961 attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt cttactgaag
     1021 caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg tatccctttt
     1081 ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc tccttattgg
     1141 cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac cttctgacct
     1201 atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa atagaagcga
     1261 agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca tttgagaaca
     1321 tgagaattag aatctttttg
//
LOCUS       DAYNVV010000156         1334 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.168, whole genome shotgun sequence.
ACCESSION   DAYNVV010000156 DAYNVV010000000
VERSION     DAYNVV010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.168"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            86..1165
                     /locus_tag="ACGXWR_002920"
     CDS             86..1165
                     /locus_tag="ACGXWR_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006908283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFK0804376.1"
                     /translation="MTQNHDNTVSRKGKHLTYSERCQIAILKKENYSNRQVADVLGCV
                     PQTINNEIKRGTVTQLNRQNQNGKVYDYYHDVYDADAGQAAYEKNRLNCGRRPLWADT
                     DAFIEWADDMMLLEKWSPDVVVGFARKHELFDPAIIPGTTTLYQWIDRGIMKTKNMDL
                     LEKLSRKPKSSRHGNRPNKRVLGKSIEERPEAVGTRKTFGHWEVDTVVGNKTKSDAVL
                     LTLVERQTRFEVILKLAGKDAESVNQAVRQLRERAGAYFGQLFKTVTSDNGSEFAGLH
                     DALQDVANIYFSHPYASWERGTSENQHKLIRRFIPKGSPIGNVSENQILRIQRWMNDY
                     PRKILGYATPHDTFVQAFRQERLTA"
BASE COUNT          359 a          357 c          369 g          249 t
ORIGIN      
        1 agccatttgg aaataaaaaa acgccacgtg aattccatgt tatattgaag ttaccacaac
       61 tctcaataga caaggatgaa ttcacatgac gcaaaaccat gataacacag tttcacgcaa
      121 gggaaaacac ctaacctact cagaacgttg ccaaatcgcc atcctgaaaa aggaaaacta
      181 ttccaaccgt caggttgcgg atgtcctggg ctgcgtgccg cagaccataa acaacgaaat
      241 caaacgcggg accgttactc agcttaaccg ccagaatcag aacgggaagg tctacgacta
      301 ttatcatgac gtctacgacg ccgatgccgg gcaggcggcc tacgagaaga accgcttgaa
      361 ctgcggcaga cggcccttat gggccgacac ggacgccttc attgaatggg cggacgacat
      421 gatgctgttg gaaaaatggt ccccggacgt ggtggtgggc tttgccagaa aacacgaatt
      481 gttcgacccg gccattatcc ctgggaccac caccctctat cagtggatcg accgtggcat
      541 catgaaaacg aagaatatgg acctgctaga aaaactgtcc cgcaaaccga aatcgtcccg
      601 tcatggcaac cgcccgaata aacgggtgct agggaaatcc attgaagagc gcccggaggc
      661 ggttggtacc cggaaaacct tcggccattg ggaagtcgac acggtcgtag gaaacaagac
      721 caagtcggat gccgtgctgc tgacgttggt ggaacggcag acacgcttcg aggtcattct
      781 gaagctggcc gggaaggatg ccgaatcggt caaccaagcg gtccgacagc tgagagaacg
      841 ggctggtgcg tacttcggcc agctgttcaa gacggttacc tcggacaacg gctcggagtt
      901 cgcgggactg cacgatgcct tgcaggatgt ggcaaacatc tacttcagcc acccctatgc
      961 ttcctgggag cgcgggacga gcgaaaacca acacaagctg attcgccgtt tcatccccaa
     1021 gggcagccca atcggcaacg tgagcgaaaa ccaaatcttg cggattcagc gttggatgaa
     1081 cgattacccg cgaaagattt tgggctatgc aacgccgcat gacacgttcg tccaggcatt
     1141 taggcaggaa cggttgacgg cttgacacgt gggcccttga caacgagcct ccctcggcat
     1201 ggcttgtgtc tggaaagctg gccggggcca gccagtcggg agactaccat gcctcagctc
     1261 attgtcaagg gcccactcga ttagaaaaat tagacggttg gtggtaacga gcaaccgggt
     1321 caccatgggt ggct
//
LOCUS       DAYNVV010000157         1298 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.169, whole genome shotgun sequence.
ACCESSION   DAYNVV010000157 DAYNVV010000000
VERSION     DAYNVV010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1298
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.169"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            143..400
                     /locus_tag="ACGXWR_002921"
     CDS             143..400
                     /locus_tag="ACGXWR_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804377.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(632..1063)
                     /locus_tag="ACGXWR_002922"
     CDS             complement(632..1063)
                     /locus_tag="ACGXWR_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HFK0804378.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          490 a          166 c          162 g          480 t
ORIGIN      
        1 ttttctgtcc acgttcatat tactccaaag ttttcctcat tccaaaagaa aagcacagaa
       61 tacacaaaga agcgttttta tttgtataaa ctatatcaaa gttctatact taaattatca
      121 aataaaaagg acgtgaagat aaatgtcaaa tttagaaaac aaagaagaaa aagttgtaaa
      181 caaaattgtt tctgttgtca ataaactgga taaagagtta gacgaacttg atacgttatc
      241 tgaaaatcca gaaaaaaaac ataacctaaa aaaatggtta gttgaacgaa aggctattca
      301 tgaaattaaa aaagttcttc atgaagctga taaatatgaa aaatatgatg aaaaagaact
      361 tgataaagaa tttaaagaaa tcaatgactt gttactataa ttgatttata cgactcattt
      421 ttgagtcgtc agactgcaaa caacactcta aatttaggag tttgtctaca gtctgaataa
      481 attttaaatt tattgtccat aatgttatta tgaatttata gcattaagaa aagagataag
      541 actttacatt tttttaggaa tgtaaagtct tatctctttt cttaattgta caattagtat
      601 tatctgcact actttctaat taaataaatt tttagttatt aacttgatta aaatcagaga
      661 taatatcatt taattcagtt tgaagggttg taacgattaa atggaaattt tcttcatctg
      721 ttttattata tggggatgtt ttcgttatat ataacaactt ttctttttca attttcatta
      781 ataactctgt cgaagtctgt actttatctt gataattaaa tgcagacatc ccactttgta
      841 taattgtaat tattgctgaa gcaattgaaa caatcaatag taaagacctg tgttcggaag
      901 cctgatcaat taatattggg atactagctg ataagactat ttttataata tttccgatac
      961 caattactct attataaaat cgaatttctt tttttaatct atcgattgta gaatcaatag
     1021 attcgataaa cgctttttga tccatcattt tctctccaat cattttatta aaatcattaa
     1081 caaaaatatt ataataggat ttaagtaagt tctaactaat cacatataaa aataaaaaaa
     1141 catttgtatt ttatcaaagt tttattatac ttgtcaattt gtgtacatcc taaaatataa
     1201 gctatttgtt tacttctgta gaatatatac tttgttgtta gataagttgc acatgtttat
     1261 agaatctaaa taataaattt ttatgtaccg cccctcaa
//
LOCUS       DAYNVV010000158         1246 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.170, whole genome shotgun sequence.
ACCESSION   DAYNVV010000158 DAYNVV010000000
VERSION     DAYNVV010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.170"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            200..742
                     /locus_tag="ACGXWR_002923"
     CDS             200..742
                     /locus_tag="ACGXWR_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804379.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1246
                     /locus_tag="ACGXWR_002924"
     CDS             898..>1246
                     /locus_tag="ACGXWR_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HFK0804380.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          514 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DAYNVV010000159         1234 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.171, whole genome shotgun sequence.
ACCESSION   DAYNVV010000159 DAYNVV010000000
VERSION     DAYNVV010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1234
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.171"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(30..1109)
                     /locus_tag="ACGXWR_002925"
                     /note="aph(2'')-Ia"
                     /pseudo
     CDS             complement(30..1109)
                     /locus_tag="ACGXWR_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
BASE COUNT          406 a          209 c          108 g          511 t
ORIGIN      
        1 gacttccttt tttgtatgga ttttttcatt tacacaaaat attttacact ctcgataaat
       61 tcctgtttaa tatttttaat tccataaaca atagtttcaa taggataata ttcttcaact
      121 atatcttgat attcttttgc tttctcaata tctatatttc catacattct taatatatct
      181 tctccaaaat ttgttcctat ttcttcttca ctatcttcaa gtaagtatat aaaatcacaa
      241 tattcatcta taattccaga atctccaaaa tcaattattc cagttaatct attattgcca
      301 tctaacaata gatgattaca actaaaatca ttatggcata aacacttttt accctcaaaa
      361 actgttgttg catttagtct ttccataaaa ctttctatat aatctttttc tatatcagtt
      421 aaatcattat aaatagtttc acgcaacaat atatactctt ctaatacatt ttgtttatta
      481 tcaatagtac attcactaat atctgtataa tctaaaccgt gcatttgtct taaaaaactg
      541 gcaatatctc gttttaacaa attttgttct tcttctgaca tagtagaata aatttctggt
      601 gttaaaaaag ttcctttaat ttctttataa cctagtatag ataattcatc actaatatac
      661 gaatattcaa tattaggaat ttttacatta gtttctaaat ttgtatttaa aaaattatat
      721 attgcttttt cttttgcata accttttttc ttattagtac taaattttgt tttaaaaatg
      781 tattcattat taactaaata tgccacacta tcataaccac taccgattat ttcaatacta
      841 tctactttga aattatcaaa gtaatgctca attaaatatt tcattgcctt aacatttgtg
      901 gcattatcat catatctata ttccattaaa taacaatctt cttttttgcc ctcgtgtaat
      961 tcatgttctg gcaaatcttc aataattcta aaaccagatt tttggtatgc ccttattgct
     1021 cttggattat ttttatgagg gtctaaaata actgcattag catttctttc ttttttcaaa
     1081 aattcaaaaa tcaatttaat atatcttgta cggttctgtt gcaaagtttt aaataaagaa
     1141 taaaatccct tacggtatct atgatttaag ctgggattcc caataatacc ttgatttcag
     1201 tacagaccga aaacccgaag agagtgcctt cttt
//
LOCUS       DAYNVV010000160         1212 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.172, whole genome shotgun sequence.
ACCESSION   DAYNVV010000160 DAYNVV010000000
VERSION     DAYNVV010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1212
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.172"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..559
                     /locus_tag="ACGXWR_002926"
     CDS             <1..559
                     /locus_tag="ACGXWR_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFK0804381.1"
                     /translation="KKFGAEKIFIEKQSGATITHRPIFQEALEFVRDQDIFIVEAIDR
                     LGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGNPHLDKFIKDLIIQILAMIAEQE
                     RTESKRRQAQVIKIAKANGVYKGRPKLYSADTKNPQRRLVYENIVKDLNEGIAISKIA
                     KNYNITRQTIYRIKNDIEYNSNQMN"
     gene            complement(556..>1212)
                     /locus_tag="ACGXWR_002927"
     CDS             complement(556..>1212)
                     /locus_tag="ACGXWR_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804382.1"
                     /translation="QFLEELSGEEYRLFLNNNILKLISYAKKANSLSLVDNLDNLLPD
                     KLIYDENEDNSQKQIIIFELYLKWLSSLSVSPESNDDDKYFANKLFQFIFPDYSSMPF
                     FTLINFMLYVKEHLGYDDLVEMIKAYDKEPYPFKGINTGSDMAMISGETVEEILANYK
                     EQNIKTLELIKKNIKYYDPLLANKENIDKLLNAIADSDVRSPRIDELKEEILMYKELF
                     "
BASE COUNT          432 a          195 c          175 g          410 t
ORIGIN      
        1 gaaaaagttc ggcgcagaaa aaattttcat cgagaaacaa tctggagcaa cgattactca
       61 tcgaccgatt ttccaggaag ctttagagtt tgtccgagac caagatattt ttattgtcga
      121 agcaatcgac cgacttggaa gaaattacga cgaaatcatt gcttcagtca attacctaaa
      181 gaagaaaaac gtgcagctga tcatcaccag tctaccgatc atggctgaag caattggcaa
      241 tcctcatttg gataaattca ttaaagattt aatcatccaa attttggcca tgattgcaga
      301 gcaagagcgt accgaatcta aacgacgcca ggcgcaagtc attaaaattg caaaagcaaa
      361 tggcgtctat aaaggtcgtc caaaactcta tagtgcagat acaaaaaatc ctcaacgacg
      421 tttagtttat gaaaacatcg ttaaggattt aaatgagggc atagctattt caaaaattgc
      481 taaaaactac aatattacta gacaaactat ttacagaatt aagaatgata ttgagtataa
      541 cagtaatcaa atgaattaaa aaagttcttt atacattaaa atttcttctt ttaactcatc
      601 aattctagga gatctaacat cagaatcagc aattgcattt aataacttat caatattttc
      661 tttattcgct agtaaaggat catagtattt tatattcttt ttaattaatt ccagagtttt
      721 tatattttgt tctttgtaat tagctagaat ttcttctaca gtttcgcctg aaatcatagc
      781 catatctgaa ccagtattga ttcctttgaa tggataaggt tctttatcat atgcctttat
      841 catttctact aaatcatcat atcctaagtg ttctttaaca tacagcataa aatttattaa
      901 tgtaaaaaat ggcattgaag aatagtctgg aaatataaat tgaaacagtt tgttcgcaaa
      961 atatttatca tcatcattgc tttctggtga cactgacagg ctgctaagcc actttaaata
     1021 caattcaaat ataattattt gtttttgtga attatcttca ttctcatcat aaataagttt
     1081 atcgggtaaa agattatcta agttatctac taaagatagg ctattagctt tcttggcata
     1141 agatattaat tttaaaatat tattatttag gaataatcta tattcttctc cagataattc
     1201 ttctaaaaat tg
//
LOCUS       DAYNVV010000161         1195 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.173, whole genome shotgun sequence.
ACCESSION   DAYNVV010000161 DAYNVV010000000
VERSION     DAYNVV010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.173"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..1076
                     /locus_tag="ACGXWR_002928"
     CDS             <1..1076
                     /locus_tag="ACGXWR_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFK0804383.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          211 g          332 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tcttg
//
LOCUS       DAYNVV010000162         1185 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.174, whole genome shotgun sequence.
ACCESSION   DAYNVV010000162 DAYNVV010000000
VERSION     DAYNVV010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1185
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.174"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..861
                     /gene="mobL"
                     /locus_tag="ACGXWR_002929"
     CDS             <1..861
                     /gene="mobL"
                     /locus_tag="ACGXWR_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase MobL"
                     /protein_id="HFK0804384.1"
                     /translation="HIHIHFAVVEKENTRKPYTEVENGVSYIVPKGKRRQATLDAMKT
                     NYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYDRHAMNLLNEVYK
                     TLPDKRSEWNYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQISKALKEEAKSL
                     YGESKRESKDAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVDQMQSIYNERSFR
                     TLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEEKYHASKAYEEQQ
                     RRIQMEQERQ"
     gene            882..>1185
                     /locus_tag="ACGXWR_002930"
     CDS             882..>1185
                     /locus_tag="ACGXWR_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804385.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVNGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKS"
BASE COUNT          485 a          178 c          243 g          279 t
ORIGIN      
        1 catatccata ttcattttgc agttgttgaa aaagaaaata cgcgtaaacc ttacacggag
       61 gttgaaaatg gtgtgagtta tatcgtaccg aaaggtaaga gaagacaagc aacattagac
      121 gcaatgaaga ccaattatgt acatgagtta gaacgttttt cttatgaaaa ggatcgaatg
      181 attggtatgg agaaacgaaa tttattgacg cggaaaagtg atttgcgtaa caccttaaca
      241 aaagtggtaa aagagccagc gcgttacgat cgacacgcga tgaacttatt aaatgaagta
      301 tataaaaccc tacctgacaa acgttcggaa tggaattacg gggatgaaaa acgaaccaaa
      361 ctttcaccat acacaagaga gaaactcgat gagttaacca aatatgtttt aacaaaagaa
      421 cctgaatatc aagaatatat acagatttca aaagcattga aagaagaagc aaaaagtctt
      481 tatggggaaa gcaagagaga atcaaaggat gcagagaaaa atgctctctt tgatttaaaa
      541 aagcgcacag gaaatgccat cctaacagag ctgaagagac aggatagtca aataaaacca
      601 ttaatagaaa gtgttgatca gatgcaatct atttacaatg aacgatcctt tcgaacgctt
      661 aaacaattgc caacgaatga atacaaatat agttacgaag aattcatgaa gcgcaggaaa
      721 caattccaac aaagagttgt cacgcagcgg agtttgcgtc aattaaatcg aacgattaat
      781 gcccatgaag aaaaatacca cgcaagtaaa gcatacgaag agcaacaacg aagaattcaa
      841 atggaacaag aaagacagta aagacagtag gaggaatagc aatgaaacaa tatttagatc
      901 aatggaaagt tatagaagga tcattaagag aagaacgaat cgaacaactt cctgattgtt
      961 tagaaaaaga gcatttgttc cagataagag aaatgttgag aaacgaacag tttgatccaa
     1021 atcaattttt agtcgttgag tacccagcta ctggtgtgta ttgttgtaat catgtgaatg
     1081 gtgaaaaata ttttatcatt caagaatatg agggcaagtt agcaccttat tatactactt
     1141 gggaaatgaa tgaagaggga atcaataact ttccatgtaa aagca
//
LOCUS       DAYNVV010000163         1146 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.175, whole genome shotgun sequence.
ACCESSION   DAYNVV010000163 DAYNVV010000000
VERSION     DAYNVV010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1146
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.175"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            72..>1146
                     /locus_tag="ACGXWR_002931"
     CDS             72..>1146
                     /locus_tag="ACGXWR_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HFK0804386.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEE
                     VKFLVTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNELRKVGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAY
                     PYFHELVEAFRDKDPDLFFSLLAE"
BASE COUNT          380 a          214 c          221 g          331 t
ORIGIN      
        1 ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca actgagagga
       61 cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag aaagatttga
      121 tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc gtcgatgctg
      181 ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta gatggaaacg
      241 ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt gaacaataca
      301 atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa aactgtcgaa
      361 cccattggac ggctcaaagt tattttgttc aacccagaca ttcaatcgcg aatcatgtca
      421 gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt gcgaaaaatt
      481 gtcaggtatc tttgaccacc gttattcgta cgttgaaaga gtttaaaagc tacttaccaa
      541 agcaatctaa gaggattctc cccagagtat tgatggttga tgaatttcgt tcgcacgctt
      601 ccatagaaga taaaatgagc tttatttgcg cagatggcga aacaggacaa ttaattgatg
      661 tcttgcctac gcgtaaattg cctcgattaa caagctattt cttaggctgc gctaatcctg
      721 aagaagtaaa atttttagtc acagacatga acgccgccta cttccagctt accaaacgta
      781 ttctgccaaa tgcgaaagta gtgattgatc ggtttcatat tatcaaacac atgaatcaag
      841 cctttaatga gttgcgtatc cgtgaaatga atgaacttcg taaagtagga cagaaaagtc
      901 aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca aacatcaacc
      961 attatgaata caaaacatgg aaaagttttc gagcaccaaa atacccattt cttacggaag
     1021 cgatgatgat tgatcgattg cttggctttt ctacgtccct gaaggaggcg tatccctatt
     1081 ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc tccttattgg
     1141 cagaac
//
LOCUS       DAYNVV010000164         1116 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.177, whole genome shotgun sequence.
ACCESSION   DAYNVV010000164 DAYNVV010000000
VERSION     DAYNVV010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1116
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.177"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(106..1065)
                     /locus_tag="ACGXWR_002932"
     CDS             complement(106..1065)
                     /locus_tag="ACGXWR_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFK0804387.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
BASE COUNT          316 a          201 c          198 g          401 t
ORIGIN      
        1 ttatcttatc gtagatatat attataaatt taataagaaa gcgaggtgag aatcgtgaaa
       61 aaaacgatac taagtatttt ttcagtattt acaatatttc gtttgtcaaa ttaagttaga
      121 caaatcatct tttgtgacgt aactcaaaaa tacttccatt ggtgtccgat agtgtaatga
      181 ttttctagga atatgatttc gtttcgatgc caccgattgg ataaaggttt cagatacacc
      241 attaaaatcc atagctttat acaaaccatc tttacgtaat aagccatttg aatgttcatt
      301 caatcctcgt tgagaaggtg ttcctggatc cgcaaaataa attgaaatat cgttggtatt
      361 actaatcttt ttccaatttg agaattcttt tccacaatca aatgtgatgg atttaaataa
      421 gttttttggg acacaacgaa accattgatt cagcctattt tcaatgtctt tagcctgtct
      481 gccttcgggt ttcaaggtaa tgatgacttt agatagccgt tcaactaatg tgatgaccgc
      541 gcttttatgt tttccaccca cgatagtgtc accttccagg tgaccaaatt catgatcaaa
      601 ctgggtatag tctgtctttc tgtctcggat tgaccggcga aacccttgtt ttcctctttt
      661 ttctttatga ccgtttggtt ttctttttcc cttcattggt aaatcgtgag tgtcaaaggt
      721 tttatcttta aacattcgat acagtgtgcg taccgaacaa gcaataggaa actctgctcg
      781 accaataagg acatcaggag cccacccttg aacaaccttt ttttgaatgt attcctgttg
      841 ctcatcaggt aaaacaatcg gatgtcttcc gcagttacgt ttgtttttct tatattgttt
      901 atagtagctc attgcgcttc caccagattt aagaaaacga tagaccttat aaatagtttg
      961 tcgagaacgt tgtaacagat tggctacttt tgaaacaggt tgtgattgat tgaaataagc
     1021 ttctatcatt acgagttcag ttggtgtaag atggttatag gtcatttgta ctcactcctt
     1081 ataattcttt cgtcggaact attttgagtg tagcac
//
LOCUS       DAYNVV010000165         1113 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.178, whole genome shotgun sequence.
ACCESSION   DAYNVV010000165 DAYNVV010000000
VERSION     DAYNVV010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1113
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.178"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..>1113
                     /locus_tag="ACGXWR_002933"
     rRNA            <1..>1113
                     /locus_tag="ACGXWR_002933"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          340 a          219 c          325 g          229 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttgg cttagaagca
      961 gccaccattt aaagagtgcg taatagctca ctagtcgagt gaccctgcgc cgaaaatgta
     1021 ccggggctaa acatattacc gaagctgtgg agtacacctt taggtgtatt ggtaggagag
     1081 cgttctaagg gcgttgaagg cagatcgtga gga
//
LOCUS       DAYNVV010000166         1062 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.179, whole genome shotgun sequence.
ACCESSION   DAYNVV010000166 DAYNVV010000000
VERSION     DAYNVV010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.179"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(37..>1062)
                     /locus_tag="ACGXWR_002934"
     CDS             complement(37..>1062)
                     /locus_tag="ACGXWR_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HFK0804388.1"
                     /translation="LTGNPKNIRLFLYNLFNSTEISFVELYTLPIIIKTEKMLKDLKQ
                     YYPLSAYEKKKLFHFLAINLLAEQADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFI
                     NKTLSWLYLHDKLDQKYLRKNEDETIEWLNERFIESFENQFNLLREETSQLIRRELTK
                     IHFKLLHYTINKADEFPLDVSFFRENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFS
                     YLLLLINHIPIQLISEPVKIIIDFSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPD
                     VIITNRNNLYEESASQVVVWLDPPRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPE
                     EIIDRIE"
BASE COUNT          346 a          177 c          160 g          379 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcgttcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgtc aa
//
LOCUS       DAYNVV010000167         1049 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.180, whole genome shotgun sequence.
ACCESSION   DAYNVV010000167 DAYNVV010000000
VERSION     DAYNVV010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1049
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.180"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..203
                     /locus_tag="ACGXWR_002935"
     CDS             <1..203
                     /locus_tag="ACGXWR_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFK0804389.1"
                     /translation="IYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYNQK
                     FLNRSHKGFQQVTDTLVSMFTE"
     gene            262..1038
                     /locus_tag="ACGXWR_002936"
     CDS             262..1038
                     /locus_tag="ACGXWR_002936"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFK0804390.1"
                     /translation="MLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNGV
                     SLARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGEL
                     ISLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKLI
                     KNNKDKYIFISKNGNPISIQAYNQSLRAVSKELNIDKKVSSHMLRHSHISLLTELGIP
                     LKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT          438 a          155 c          137 g          319 t
ORIGIN      
        1 ccatttactc aaccaatcta atcgagtctt tcaataagca aattaaaaga tacagccgta
       61 gaaaagagca gtttcaaaat gaagaatcac tagaacgctt tctagtcagc atttttgata
      121 catacaatca aaaatttcta aacagaagcc ataaaggttt tcaacaggta accgatacat
      181 tagtttcaat gtttactgag taactaatta ttttgcagga ggacaattta tttacacaaa
      241 attattgacg ctccccaaga tatgctagat tactactatt ttgaaaaaaa tttatcatat
      301 aattatgtaa tacatttaaa aacttttaca ggaatgattt ttaaattcgc caaccgtcga
      361 tatggattaa aatataatcc cgtaaatggg gtttctttag caagaaaacc taagacaaac
      421 gaagaaataa aaaaagaaaa agatggttat ttatcaaaag aagaagttca aatgattgct
      481 agtaaacaaa aaagttcaca tcaacagtca cgttattctt taattactaa atttttgttt
      541 ttaactggac tacgttatgg tgaattgata tctttgactg aatctgatta tgatggtaat
      601 aaaattacgg tttctggtac ttatgattac gagttaaaaa ttaaaacaac aactaaaaat
      661 acaggttctt atagaaccat tgaattatca agtaatgcta aagaaatcat agatcaatta
      721 attgaagaaa acaaattaat taagaataat aaagataaat acattttcat ctctaaaaat
      781 ggtaacccga tatctattca agcatataat caatctttaa gagcagtatc caaagaatta
      841 aacatagata aaaaagtttc ttctcacatg ttaaggcatt cccacatttc tctacttaca
      901 gaattaggaa tcccattaaa agccattatg gatcgtgtag gacatgaaga ttcaaaaaca
      961 acattaaaga tttatactca tacaactaaa aatatgcaaa atcaactagt agaaaaacta
     1021 ggaaaaatag aaatttaaat tgccccttt
//
LOCUS       DAYNVV010000168         1001 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.181, whole genome shotgun sequence.
ACCESSION   DAYNVV010000168 DAYNVV010000000
VERSION     DAYNVV010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.181"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            370..1001
                     /locus_tag="ACGXWR_002937"
                     /pseudo
     CDS             370..1001
                     /locus_tag="ACGXWR_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          343 a          181 c          183 g          294 t
ORIGIN      
        1 gtttcaaagt tagtagagaa aatgtagtta tatatttaaa tttttaccag aaagaaatga
       61 acaccttcaa ttatctaaat ctcgaaaatg gttagatgta atcatcagga aaaacaatct
      121 taaacgaatt actattcatg gtcttagaca cacacatgct agcttgcttt tagcaagcta
      181 gtgcaaatat taaagatgtg caagagcgtt taggccactc ttctattcaa atcattatgg
      241 atctatatat tcatattaca gacaaaagaa aagaagaaac cgtagcgcaa ttcgcaaaat
      301 ataggctcta taatttatgg gactgatgaa tcaaaattga ttcttcagtc ccattgttat
      361 tttaggtata tgattcgtac attgaaagag ttgaaaaact atcttccgaa gccgtcaaaa
      421 aggaccctgc caaaagtatt gatggtggat gaatttcgtt cgcacgcttc aattgtggat
      481 aaaatgagct ttatttgtgc ggatggcgag actggaaaac tcattgatat tttgcctaca
      541 cgaaaattgt ctcgattaac acactatttt agtcgctgtg caaatcctga agcggtggaa
      601 tatttagtga cagatatgaa cgccgcctac ttccaactga caaaacgtgt cttaccaaat
      661 gcgaaagtcg tcattgattg ttttcatatc atcaaacatt tgaatcaggc gttcaatgat
      721 tttcgtgtac aagaaatgaa aagattacac cagttagggc aacgacggga agccgagaaa
      781 gtgaaaaaga actggcgctt tcttctaaaa aaccgtcaaa aaatcaatca ctatgattac
      841 aaaacatggc gcagttttcg tgcacctaaa tacccactac tcactgaagc aatgatgatt
      901 gatcgattgc tggcattttc aacgccttta aaggacgcct atactttttt ccatgagctg
      961 accgaagcct ttagagacaa ggaatcagac ttatttttta c
//
LOCUS       DAYNVV010000169          940 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.183, whole genome shotgun sequence.
ACCESSION   DAYNVV010000169 DAYNVV010000000
VERSION     DAYNVV010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..940
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.183"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            168..746
                     /gene="pgsA"
                     /locus_tag="ACGXWR_002938"
     CDS             168..746
                     /gene="pgsA"
                     /locus_tag="ACGXWR_002938"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HFK0804391.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
BASE COUNT          267 a          162 c          212 g          299 t
ORIGIN      
        1 aaaaagaagg atcgtgacaa atctgtgtcg cggtccttct tcgttaattc aaaaagatca
       61 atttcaataa aaatactcct ttgaataaat tcatttggaa aagtaaataa tatcggtgga
      121 aacttcgctg atagtcacgt agaataggga agaaaggagt cgatagtgtg aatttaccaa
      181 ataaattaac tgtacttaga atttgtatga tcccgatttt cattttggtt gtaggtttac
      241 ctttagattg gggacaattt aacgtaggag acaccacact ggctgtcaca cagctagtag
      301 gtgcagttat ttttgcttta gctagtatca cagactggtt agatggaaaa attgcccgtg
      361 cgcgaggcct tgtcactaat tttggcaagt ttgcggaccc gttggcagat aaaatgctag
      421 ttatgactgc ttttatcatg ttggttgacc aaggaaaggc ccctggttgg gtagtagcga
      481 tcattgtctg tcgtgaatta gccgtcacag gcttgcgttt actacttgtc gaacatggag
      541 aagtcatggc tgcagcttgg ccgggaaaag tcaagacggc tacacaaatg gttgctatta
      601 tcttgctgtt tatcaataat atcccattca gcctgatcgg tattccagta gatcaaatca
      661 tgctttatgc ttgtctgatc tttactatct attcaggtgt ggattacttc atcaaaaaca
      721 gcggtgtgtt caaaggatca atgtaagtat cgtttagtgg agaggttgtg agcctgccgt
      781 ctaactctga gtcacaaggg ataatttcaa aaaacagctt ttcatgtttt atgtatattg
      841 tgacttatga ccgaggtttt ggcaggagaa cactgtttat ttggaacaag gagctgtgac
      901 aagatttttg tcacagctcc ttgccctctt tttaaataaa
//
LOCUS       DAYNVV010000170          906 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.184, whole genome shotgun sequence.
ACCESSION   DAYNVV010000170 DAYNVV010000000
VERSION     DAYNVV010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..906
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.184"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..879
                     /locus_tag="ACGXWR_002939"
     CDS             <1..879
                     /locus_tag="ACGXWR_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFK0804392.1"
                     /translation="SRAINYAEPRATIKTGINCDVDYAKSEMKQIRMLYGKDDRVQAH
                     LLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHNHIVINSVNLETG
                     KKFQAHGQAFLNKCYDLNDEICLAHNLPITERGKKPEKRTMSEIKLKEKNEPVWKDEI
                     RIAIDQTMKNKKTRTYDQFCNSLKTLGIHCFNRGKNFTYELIHKKKKVRSNRLGKDYE
                     KETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTLTPEQPEIRPARRNH
                     EQHVERGTDHQQELSL"
BASE COUNT          377 a          185 c          166 g          178 t
ORIGIN      
        1 agtcgtgcaa ttaattacgc agaaccacga gcaaccatta aaacaggaat aaactgtgac
       61 gtcgattatg ccaaaagtga aatgaaacaa attcgcatgc tgtatggaaa agacgaccgt
      121 gtacaggcac acttattgat tcaatctttt cgaccaggag aaattaccgc tgaaaaagct
      181 aatcaactag gggcagagta tgcaaaaaaa atagcccccg atcaccaaat agctatttac
      241 acacatacag acaaagacca tattcataat cacattgtca ttaactccgt taatctggag
      301 actggaaaaa aatttcaagc tcatggtcaa gcatttctaa acaaatgtta tgacctaaat
      361 gacgagattt gtcttgcaca taacttacca atcactgagc gaggaaagaa accagaaaaa
      421 cgaaccatgt ctgaaataaa attaaaagaa aaaaatgaac ctgtttggaa agacgaaatt
      481 cggattgcga tcgatcaaac aatgaaaaac aaaaaaacca gaacctatga ccaattttgt
      541 aattccctca aaacattggg gattcattgc ttcaatcgcg ggaaaaattt cacttacgaa
      601 ttgatccaca aaaagaaaaa agtacgatcc aacagactag gaaaggacta cgaaaaggag
      661 acgattttac atgagctgga cagacgagaa cgaacctata accaacagcg aaccaacgag
      721 ctacgaagag ctcgagctag cattcgcgaa actgcagaag aagtacgaag agaacaacga
      781 actcttacgc ctgaacaacc ggaaattaga ccggctcgaa gaaaccatga acaacacgtt
      841 gaaagaggaa cagaccacca acaagaatta tcgctctaaa acgttaaaag acatagaaaa
      901 cgaaat
//
LOCUS       DAYNVV010000171          899 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.185, whole genome shotgun sequence.
ACCESSION   DAYNVV010000171 DAYNVV010000000
VERSION     DAYNVV010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..899
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.185"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            46..105
                     /gene="ermCL"
                     /locus_tag="ACGXWR_002940"
     CDS             46..105
                     /gene="ermCL"
                     /locus_tag="ACGXWR_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002497446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methylase leader peptide ErmCL"
                     /protein_id="HFK0804393.1"
                     /translation="MGIFSIFVINTVHYQPNKK"
     gene            165..899
                     /locus_tag="ACGXWR_002941"
     CDS             165..899
                     /locus_tag="ACGXWR_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011282421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(T)"
                     /protein_id="HFK0804394.1"
                     /translation="MNKKNIKDSQNFITSKHHINEILRNVHLNTNDNIIEIGSGKGHF
                     TFELAKRCNYVTAIEIDPKLCRITKNKLIEYENFQVINKDILQFKFPKNKSYKIYGNI
                     PYNISTDIIRKIVFESTATESYLIVEYGFAKRLLNTNRSLALFLMTEVDISILSKIPR
                     EYFHPKPRVNSSLIVLKRHPSKISLKDRKQYENFVMKWVNKEYIKLFSKNQFYQALKY
                     ARIDDLNNISFEQFLSLFNSYKLFNR"
BASE COUNT          378 a          110 c          117 g          294 t
ORIGIN      
        1 cttgtgctat aattattcta atttcataaa aaggagaatt aatatatggg catttttagt
       61 atttttgtaa tcaacacagt tcattatcaa ccaaacaaaa aataagtggt tataatggat
      121 tgttaatata aacattcatt ataacctcat aggagtgggt tataatgaac aaaaaaaata
      181 taaaagatag tcaaaacttt attacttcaa agcatcatat aaatgaaatt ttgagaaatg
      241 tacatttaaa tacaaatgat aatattattg agattggttc agggaaaggt catttcacgt
      301 ttgaattagc taaaaggtgt aattatgtaa ccgccattga aatagatcct aaattatgta
      361 ggataactaa aaacaaactt attgaatatg agaacttcca ggttatcaat aaagatattt
      421 tacaatttaa gtttcctaaa aataagtcat ataagatata tggaaatata ccctacaata
      481 taagtacaga tataattcga aaaattgttt ttgaaagcac agctacagaa agttatttaa
      541 tagtggaata tggatttgct aaaaggttgc taaatacaaa tcgttcacta gcactatttt
      601 taatgacaga agttgatata tccatattaa gtaaaatccc tagagaatac tttcatccaa
      661 aacctagagt taatagctcg ttaattgtat taaaaagaca cccttcaaaa atatcactca
      721 aagatagaaa acaatatgaa aattttgtta tgaaatgggt taacaaagaa tacataaaac
      781 tattttccaa aaaccaattt tatcaagcct taaaatatgc aagaattgac gatttaaaca
      841 atattagctt tgaacaattc ttgtctcttt tcaatagcta taaattattt aatagataa
//
LOCUS       DAYNVV010000172          882 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.186, whole genome shotgun sequence.
ACCESSION   DAYNVV010000172 DAYNVV010000000
VERSION     DAYNVV010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..882
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.186"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            51..>882
                     /locus_tag="ACGXWR_002942"
     CDS             51..>882
                     /locus_tag="ACGXWR_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFK0804395.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     V"
BASE COUNT          305 a          155 c          168 g          254 t
ORIGIN      
        1 tgctacactc aaaatagttc cgaccaaaga attataagga gtgagtacaa atgacctata
       61 cccatcttac aacggatgaa cttgtaataa tagagtctta tttcaaaatg aatcaatctg
      121 ttgctaaaac tgcccattgc ttgaatcgtt caagacaaac gatccataaa gtatatctgt
      181 tcttcaagca aggaaaatca gccttagaat attatcaaca gtataagaaa aacaaatcaa
      241 actgtggtag acgtccgctt gttttacccg aggaacaatc agaatatatt caaagaaagg
      301 ttgttcaagg atggacaccc gatgtgattg ttggtcgtgc agcgtttcct attagttgtt
      361 ctgctcgtac catttatcgt atgttcaaaa aggggctatt tgattcttct gacttaccga
      421 tgaaaggcaa gcgtaaaccg aatggacatc aagaaagacg tggaaaacaa actttccgcc
      481 gctctattca tgaacgtgaa aaggattata gccaattctc aaatgagttt ggtcaccttg
      541 aaggtgacac tatcgtaggt ctgaaacata aaagtgctgt aattacctta gttgaacgat
      601 tatcaaaagt tatcatcaca ttgaaaccgt gtggtagaca agcgattgat attgaaaaaa
      661 aattaaatca atggtttgaa tctgtaccga aaaacctatt caaatccatc acttttgatt
      721 gtggaaagga attttcaaat tggaaacaga tcagtaatgt caatgatatt gccatttatt
      781 tcgctgatcc aggaacgccg tctcaaagag gcctaaacga gaattctaac ggattgttac
      841 gtagagatgg tttattgaaa tctatggatt tcaattcagt ag
//
LOCUS       DAYNVV010000173          811 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.187, whole genome shotgun sequence.
ACCESSION   DAYNVV010000173 DAYNVV010000000
VERSION     DAYNVV010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.187"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            178..774
                     /locus_tag="ACGXWR_002943"
     CDS             178..774
                     /locus_tag="ACGXWR_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFK0804396.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT          233 a          122 c          150 g          306 t
ORIGIN      
        1 ttaaaaaaaa caagttatta aataagtctt tagttggatg tttttttgag atcaatcttt
       61 tatacttatg atgaacttac aaaattgttt gttttctgtc atatcaaaaa atggcgcagt
      121 tagttgcttt tctagtaaag tatagttaac aaagaacctc taaggagttg atgaataatg
      181 aatattgctg cctctcgaaa actgataaat ttcatatcca ttatcggatt aggcctatca
      241 atcgcgctga cgatttattt tattaattta ggtgttttca aagatttgaa tgcgttaaga
      301 ggattagtag gtgattccat cattttagga ccgattattt ttgtcttcat ccaaatcctg
      361 caagtagtta ttccaatcat tcctggaggg atcagtactg cagctggtgt cctgatattt
      421 ggcccttatg ctggatttat ctataactat attggaatct gcattggttc gattatcatt
      481 tttctgctag ggcgtcgtta tggaaagcca ttcatacttt ccatgattag cgataagaca
      541 tataacaaat atattggctg gctggataat caaaaccgtt ttgagaagct gtttgctcta
      601 gctatttttc ttccagttgc tcctgacgat gcgttatgtt tgatggctgg attgacaaac
      661 atgtcagtga aacgatatac actaatcatt ttgattgcta aaccactgtc gattttctta
      721 tatagtatgg ccttgattta tggaggtcaa tatctaagtg gtcttcttgg ataatattta
      781 ttttgtaaaa ttagtcattg attgacaatg t
//
LOCUS       DAYNVV010000174          789 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.188, whole genome shotgun sequence.
ACCESSION   DAYNVV010000174 DAYNVV010000000
VERSION     DAYNVV010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..789
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.188"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..672
                     /locus_tag="ACGXWR_002944"
     CDS             <1..672
                     /locus_tag="ACGXWR_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFK0804397.1"
                     /translation="SGKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDN
                     NKFTSKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTD
                     FLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRK
                     IIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLH
                     SMGLA"
BASE COUNT          292 a          122 c          146 g          229 t
ORIGIN      
        1 agcggtaaat actatatttc tttgttgtgt aaagaagaaa ttatcgaatt acctaaaact
       61 aattccacaa ttggtattga cttaggtatt atggactttg cgattctttc tgatggacaa
      121 aaaattgata ataataaatt cacgtccaaa atggaaaaga aactaaagcg tgaacaacgc
      181 aaattgtcta ggcgtgcttt attggctaaa aataaaggta ccaatctatt tgaagctaaa
      241 aattatcaaa aacaaaaacg caaagtagct agattgcatg aaaaagtaat gaatcaacgt
      301 actgattttc tgaataagtt gagtacagaa atgatcaaaa atcacgatat tatctgtatt
      361 gaagacttaa acacaaaagg tatgttgcga aatcataaat tagctaaaag tatttctgat
      421 gtttcttggt caaagtttgt gactaaatta caatacaagg ctgactggta tggacgaaaa
      481 atcatcaaag tagataaatg gtttccgtct agtcagattt gttcagagtg cggacataaa
      541 gatggcaaga aatctcttga aattcgagaa tggacttgtc ctgtttgtca tactcatcat
      601 gatcgtgata tcaatgctag tatcaatatt ctgaccgaag gtctaagact acattctatg
      661 ggattggctt agatccaatc atcaagaacc gtaggaacta cggggatagc ttggtaaata
      721 agagacaccg ctgttagtaa agaaatacgc tatcaagtat gctctattcc caagaagctc
      781 ccacttcaa
//
LOCUS       DAYNVV010000175          765 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.189, whole genome shotgun sequence.
ACCESSION   DAYNVV010000175 DAYNVV010000000
VERSION     DAYNVV010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.189"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            660..>765
                     /locus_tag="ACGXWR_002945"
     rRNA            660..>765
                     /locus_tag="ACGXWR_002945"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          315 a          124 c          134 g          192 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaaaa gttattgaca tgttactaac gacatgataa gataactgag tcgttaaaaa
      301 agaaccactt gcgaagcttg attctatcga aaaaaacttc aaaaaagttc ttgacaaata
      361 acaaacgata agttatgata aatgagttgc cgaaagattt cgaaaaacga aatcgaaaaa
      421 aacttttaaa aaagagttga caatcgcttg tctctctgat atgatataaa agttgctacg
      481 gcagccaaaa atgaatcggg aaacactctc gatgaagtag acctttgaaa actgaacaaa
      541 gtaagacaaa ccaaatgtgt agggcgtctt gattcaattc aagacaacaa acatttttaa
      601 caagcaagca atatgctagc aaacaaattg agcttaacaa tcgcaagatt gttcgaactt
      661 tttatgagag tttgatcctg gctcaggacg aacgctggcg gcgtgcctaa tacatgcaag
      721 tcgaacgctt ctttttccac cggagcttgc tccaccggaa aaaga
//
LOCUS       DAYNVV010000176          762 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.190, whole genome shotgun sequence.
ACCESSION   DAYNVV010000176 DAYNVV010000000
VERSION     DAYNVV010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..762
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.190"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(109..>762)
                     /locus_tag="ACGXWR_002946"
     CDS             complement(109..>762)
                     /locus_tag="ACGXWR_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
                     /protein_id="HFK0804398.1"
                     /translation="GRIMKRRGLTSTYTIAHFKGQRTACNEAKTANVLDRTFTQEQPL
                     EAIVTDLTYVRVGKKWHYICLILDLFNREIIGYSCGEKKDASLVKEAFGRIPYSLTDV
                     KLFHTDRGKEFDNQTIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQF
                     ETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          212 a          175 c          145 g          230 t
ORIGIN      
        1 gacaaaaatt ataaggtgtt gtgaatgctg cggtgttatg gctacgattg cccttgacaa
       61 tgagcatcct cggatctgat tttctccggc agaagcacaa tcattcaatt acgctgcctc
      121 tccagaggta tcagatccgc gctcattatc aaggattcgc ttcgccaatc tctgttgtcg
      181 aatttggatc ggtgtttcat acgccaacgt gccatgtaag cgtagatagt tccaccaatg
      241 cacataatca aacaattcta gacgtagctg tgccagtgtc tcaaattggt attgatgcac
      301 gaattctact ttgacagatt tataggttga ttccacaacg gcattatcat acggacaacc
      361 cttcctactc aatgaacgag taattccaaa accattcaga atctcatgaa tggtttggtt
      421 atcaaattcc tttccccggt ctgtatgaaa aagcttgacg tctgttaaag aatacggtat
      481 ccgtccaaag gcttctttta ccaatgaggc atctttcttc tcaccacagg aataaccaat
      541 aatttctcga ttaaacaaat caagtattaa gcagatataa tgccactttt tccccacgcg
      601 aacataagta agatccgtaa cgatggcttc caatggctgt tcttgtgtaa aggtccgatc
      661 taatacattc gctgttttcg cttcattaca agctgttcgt tgccctttaa aatgagcgat
      721 cgtataggta gatgtcaatc cgcggcgttt catgattcga cc
//
LOCUS       DAYNVV010000177          761 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.191, whole genome shotgun sequence.
ACCESSION   DAYNVV010000177 DAYNVV010000000
VERSION     DAYNVV010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..761
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.191"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            51..731
                     /locus_tag="ACGXWR_002947"
     CDS             51..731
                     /locus_tag="ACGXWR_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HFK0804399.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEI
                     KVLLGIPA"
BASE COUNT          270 a          127 c          152 g          212 t
ORIGIN      
        1 tactatcaaa taaggtagaa taatagaaaa agatagcagg aggaatgacg atgaatcatt
       61 ttaaaggaaa gcaatttcag caggatgtga ttattgtagc cgtgggctac tatcttcgtt
      121 ataaccttag ctatcgtgaa gttcaagaaa tcttatatga tcgtggcatt aacgtttctc
      181 atacgacgat ttatcgttgg gtgcaagaat atggcaaact actctatcaa atttggaaaa
      241 agaaaaataa aaaatccttt tattcatgga aaatggatga aacgtacatc aaaattaaag
      301 gaaaatggca ttatttgtat cgagccatcg atgcagatgg tttaaccttg gatatttggt
      361 tacgtaaaaa acgggacaca caagcagcct atgcttttct taagcggtta gtgaagcagt
      421 ttgatgaacc gaaggttgta gtcacagata aagccccctc tattacaagt gcctttaaga
      481 aactaaaaga atacggcttt tatcaaggga cagaacatcg taccattaaa tacctgaata
      541 atttgattga acaagaccat cgtccagtaa agagacgcaa taaattctat cgaagtttac
      601 gcactgcctc taccacgatt aaaggcatgg aagccattcg aggattatat aagaaaaccc
      661 gaaaagaagg cactctcttc gggttttcgg tctgtactga aatcaaggta ttattgggaa
      721 tcccagctta aatcatagat accgtaaggg attttattct t
//
LOCUS       DAYNVV010000178          759 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.192, whole genome shotgun sequence.
ACCESSION   DAYNVV010000178 DAYNVV010000000
VERSION     DAYNVV010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..759
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.192"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..339)
                     /locus_tag="ACGXWR_002948"
     CDS             complement(<1..339)
                     /locus_tag="ACGXWR_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0804400.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYT"
     gene            complement(356..>759)
                     /gene="tnpA"
                     /locus_tag="ACGXWR_002949"
     CDS             complement(356..>759)
                     /gene="tnpA"
                     /locus_tag="ACGXWR_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HFK0804401.1"
                     /translation="ELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERISE
                     SYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKEM
                     FWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
BASE COUNT          228 a          124 c          123 g          284 t
ORIGIN      
        1 tgtataactc tgaacaggat ttttcttact tttgaaacgt ggaaatccaa cggatttatc
       61 ccgaaaaaaa ttcttgtatg ctttatctaa attaagttgg gcattggcta aagcaaggct
      121 atcaatttct ttcaaaaacg gaaattcttt cttgtattta gctggtgtcg gaaaagtcat
      181 ttttttagaa gaatcatttt taacttcttc atacgccttt tttcggtcat caagcattag
      241 attgtagacc ttacggacac aaccaaaaga tttggcaaag aagatttctt gttcctctgt
      301 tggatagatt ctgaatttgt atgcttttag ttgttccata aagttcacct actttctatt
      361 tatgattgtt tccttgattt tggatatact tcttaatcac atcaattggt gcgccaccag
      421 ttgtcagaag acaaaaactt ttagaccaga acatttcttt ccaaagaaat tgtttgactc
      481 ttggaaagtc acgttttatc aatcttgagc tggcactttt ataggcattg atgaattttg
      541 tcaattctgt tttaggttga gctttgaaca taatatgaac gtggtcttta tcatgattcc
      601 actccactaa agtaatgtga tacgattctg aaattctttc aaaagtagtt ttggcataat
      661 cagatatttc atcatcaatc acttgtctac gatatttcgt tactaaaaca aggtggtaat
      721 aaagaagaaa tactgaatga ttatttgtat ctaattcca
//
LOCUS       DAYNVV010000179          714 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.193, whole genome shotgun sequence.
ACCESSION   DAYNVV010000179 DAYNVV010000000
VERSION     DAYNVV010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..714
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.193"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..448)
                     /locus_tag="ACGXWR_002950"
     CDS             complement(<1..448)
                     /locus_tag="ACGXWR_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0804402.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
BASE COUNT          216 a          124 c           95 g          279 t
ORIGIN      
        1 tcaactttct cttttcaaaa aaaatttgat atttttttag atttcttttt agtctttgta
       61 atactttata agccacagaa taactcacgt gatgctgttt agcaaaattt tctactgaga
      121 tatatttttc ctgaaagaaa gccaatacca ttttcataga taaagaatcc gttatataac
      181 gagataacag agctttgcta gaacattttc cattaatttc cagacatata tccaattcac
      241 tgacggttac tcgcaaattt ttctctagat cgaacttttg taaatcatgt ttcagcttat
      301 cgatcgtttt tttcaagaga aatgtcgata gcgacaactc ttcttgaaca ttcgatattg
      361 actctgataa atttgagctt gcttctaaat atttaagtaa tgaataactt ctgtgatctt
      421 ctttgcttaa aaaaaactca taattcatta gtcatcagct ctttctacgt atattacttt
      481 ccatgcattc accaactagc tggggataaa actgatttcc tggatccgag tcactgttgt
      541 cagcgattct tgtttgtata atatacatcg tcctgtcttt tttttaacat tttggagagc
      601 gttttatttg gcctttctcg cgatcaaacc tgttattaga attatatcat ttactagtat
      661 gcatttttat taataaaatg gtatatttta tattgttata aaaagagccc aacc
//
LOCUS       DAYNVV010000180          697 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.194, whole genome shotgun sequence.
ACCESSION   DAYNVV010000180 DAYNVV010000000
VERSION     DAYNVV010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..697
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.194"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..340
                     /locus_tag="ACGXWR_002951"
     CDS             <1..340
                     /locus_tag="ACGXWR_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804403.1"
                     /translation="GLPFLYGFFHLHKIFYTLILIQDDLHHTHRLWLMNKINLYFGHS
                     YVFAFYDYRTNITEVDLVISNYYIDTGKTPLLLMKNIPTERNWRLFEKTIYQLKKEKE
                     VVKSAFCPEY"
BASE COUNT          232 a           98 c          125 g          242 t
ORIGIN      
        1 gggacttcct tttttgtatg gattttttca tttacacaaa atattttata ctctcatttt
       61 aatacaagat gatttacacc atacgcatcg gttatggtta atgaataaaa ttaatctgta
      121 ttttgggcat tcttatgttt ttgcttttta tgattacagg acaaatataa ctgaagtaga
      181 tttggttatt tctaattact acatcgacac tggaaaaacg ccattactgt taatgaaaaa
      241 tatacctacc gaaagaaact ggcgtttgtt cgagaaaacg atttatcaat tgaaaaaaga
      301 aaaagaggtt gtgaaatcag cgttttgtcc tgagtattag agaaacaaac ggaaaaatag
      361 tttttcatat tttgccgttt ttgagctaat accgagggac agctgattga acaccattta
      421 ttgagagatt gtgaaaaaac tgtcctgcat caagtaataa gaacagccaa gtaaaaacag
      481 cttctcatgt ttgttgaata ttgtgacttg tgaccgagga gttggcaaga gaacaccgtt
      541 tattcggaaa aagggactgt gacactacat gtcacagtcc ctttttgatt gaattatctc
      601 atttgttttc taattttttc tttatttgag aaaatagttg aactggataa aaagtactgg
      661 acgtgtcaaa attattttgg atcaaattag atctatt
//
LOCUS       DAYNVV010000181          696 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.195, whole genome shotgun sequence.
ACCESSION   DAYNVV010000181 DAYNVV010000000
VERSION     DAYNVV010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.195"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(53..628)
                     /locus_tag="ACGXWR_002952"
     CDS             complement(53..628)
                     /locus_tag="ACGXWR_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytS/YhcK type 5TM receptor domain-containing
                     protein"
                     /protein_id="HFK0804404.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          229 a          151 c          125 g          191 t
ORIGIN      
        1 atgaaaaaac agagccagat tagcattatt ttgctaatcc agctctgttt attcagccta
       61 tttttctttt tgaatatatc aagcgttggg gcaacatagt gatgactaat gaaacaacga
      121 cgatagacaa caagcgatca aggtagtctg tacccgcctg taccaagatc acacttgttg
      181 tctgacttaa acctaaccca tgtaatagct gaacgatcat actggatcct gaggaggtga
      241 tcccgccaaa taactgaacg gtaatgatcg aagaaacgat cgttccaggt accgacaaaa
      301 tcaaagcgag taataacagt ttcaagctgt ttttatcttt gccgagatat cttggcaaaa
      361 tcaatccagc aagcaagcct gtgagaattt ggattggcga ataatacaga gaaaaaatat
      421 ctgtagtcac tccacttaaa ataccgctgg acaatcctgt cagcattcca ggtacaggcc
      481 caagcaatgc accagcaaaa atcgttccga tagaatcgag atagattggc aaacgaagcc
      541 ataaagcaat cgttcctcca atataattga tcccaataca caaagccatc actgtaagta
      601 cgcgagttgc cattttgttt ttattcattt tgttagccca tctttaacct ttccaaatct
      661 ttcataatcg tttcttcttg tgcatttaaa agaacg
//
LOCUS       DAYNVV010000182          675 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.196, whole genome shotgun sequence.
ACCESSION   DAYNVV010000182 DAYNVV010000000
VERSION     DAYNVV010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..675
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.196"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
BASE COUNT          231 a           94 c          138 g          212 t
ORIGIN      
        1 acggtatgtg gttaaaaaag aaaaatagct aggagatttt tgagagatga ctggtaaatt
       61 taaaaatgat agaaatggag agtatgtatg agtaataaac aatttttatg gtcttctttt
      121 gcatttattg ttgttgatat ttttttccga tattttaata acgatatgat atttaactgg
      181 caaagaatta taatcgatta ctgtattttt tgtataatat attttttagt gaaaacattt
      241 ctaaaatacg caaaaaaata aaattgaaga tgttattaaa tcgcgattat ttacggagat
      301 ttatataaat aaaaaccccc tgacgaagtc gaagggggtt tttattttgg tttgaggttt
      361 gcatacctac cgaaaaggta gggcagcaaa tcgtcaaaca ggtatcagct aattgcacca
      421 taagggtgcg ctgatactcg gctcaaaaga gccgaaagag ccgtctgcaa gacccctcgg
      481 cgagcccaca ctttgcttgc aaagtatagt gggttatact ttacatggaa gtaattgccg
      541 gaaatagtga aaatgcctca catttgtgcc acctaaaaag gagcgattta catatgagtt
      601 atgcagttta cgggccaaga ttgtttaagc aaaataagat aagttaaggg atgcagttta
      661 tgcacccctt aactt
//
LOCUS       DAYNVV010000183          661 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.197, whole genome shotgun sequence.
ACCESSION   DAYNVV010000183 DAYNVV010000000
VERSION     DAYNVV010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..661
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.197"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            63..>661
                     /locus_tag="ACGXWR_002953"
     CDS             63..>661
                     /locus_tag="ACGXWR_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
                     /protein_id="HFK0804405.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVK
                     YLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGI"
BASE COUNT          231 a          115 c          131 g          184 t
ORIGIN      
        1 aaagttttcc aaaaaatcta ttttagtgta aaattgagaa aaaagacaga gaggacagag
       61 taatgaatca ttttaaaggc aaacaattca aaaaagacgt cattattgtc gctgttggtt
      121 actacctgcg ttacaatcta agctatcgtg aagttcagga attgttatat gatcgtggaa
      181 taaatgtttg tcatactacg atttatcgtt gggtgcaaga gtacagcaaa gtcctctatt
      241 atctttggaa gaagaaaaat agacaatcct tctattcatg gaaaatggac gaaacctata
      301 tcaaaattaa gggacgttgg cattatcttt atcgtgcaat tgatgcggac ggcttaacct
      361 tagatatctg gttacgaaag aaacgggata cgcaagcagc ctatgctttc ttaaaacgac
      421 tccataaaca gtttggtgag ccgaaagcaa ttgtgaccga taaagcacct tctcttggct
      481 ccgcctttag aaagttacag agtgtgggtt tatatactaa gacagagcac cgaactgtga
      541 agtatcttaa caatttaata gaacaagacc atcgacctat taaacgacga aataaatttt
      601 atcaaagtct ccgtacagcc tcttccacga ttaagggcat ggagaccatt cgaggaatat
      661 a
//
LOCUS       DAYNVV010000184          604 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.198, whole genome shotgun sequence.
ACCESSION   DAYNVV010000184 DAYNVV010000000
VERSION     DAYNVV010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.198"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
BASE COUNT          226 a           97 c           68 g          213 t
ORIGIN      
        1 aaatcgtgtc catgaaatca tcctaacatc attaaaaacc acgataggta actttaaaca
       61 aacatgaaga gactttaata agacttcttt atctgaaaac acttttgttt ctctctttcc
      121 tttctacatc attaaatagt attttatacg ttatctaaaa tactattcct ctgtcaaaat
      181 aagctaactt acttcattat aaaatatcca cttatcgctt tcatgtatat tccaccgtaa
      241 aaagtacatt ttatcaccga gaactcatca tttttcatca tgatgaatac tatttacata
      301 tatctagttc aaagacaata attattatga tccgttatta tctaagcact atacagataa
      361 taggaatttt tcgtttctaa atattccaat ttgggaatcc aataaaaatt ttcgttcaaa
      421 tacgtgtcta ttcgaactct tttctagttg ttaattatga agggggaaga aataaaaaat
      481 acaatctata cacgaataag aatattatcc aaaaggaggt tttagaaaag atttattata
      541 cgtaaaaagc tcaagacatt ttcttagcca taaggacatg tttgatattt aagaagatat
      601 atga
//
LOCUS       DAYNVV010000185          597 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.199, whole genome shotgun sequence.
ACCESSION   DAYNVV010000185 DAYNVV010000000
VERSION     DAYNVV010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.199"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..355
                     /locus_tag="ACGXWR_002954"
     CDS             <1..355
                     /locus_tag="ACGXWR_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804406.1"
                     /translation="GAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETNMTRDELL
                     RKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTTSQIKQDT
                     EDSLRKGWGMNNKVR"
BASE COUNT          227 a           72 c          120 g          178 t
ORIGIN      
        1 tggcgcacca atcagaaagt ttgataaggt ttattccacc aagcatcctt taaaactgtc
       61 gactttgtta aatgcgactt ccagagtttt agtagaaaag tatgagacta atatgacaag
      121 agatgaattg cttagaaaag ctttagatga gtatattaaa cagaatctta cgcaagaaga
      181 taagcaagat ttgtttaatg acgtggtgaa agaactagac ttgttcagag aaaaatatcc
      241 aattgttcca gaattagatg atcgtggaga aataataaga actaccagtc agataaaaca
      301 agataccgaa gactcactgc gcaaagggtg gggaatgaat aataaagtta gataataatc
      361 aaagaagaac taagtaacta cctttaaacg gtagttactt agttcttctt tgatttgcat
      421 gaaatagagg ggatttattt ttctggttac gtgattaaaa aatccaaaaa atgagcatag
      481 gaacggttat gattttaggg tgtgttttaa tgagatattg tgatttcatt aacaagtgta
      541 tgataatctg ttgttgagtt agtaaataag taatagagct aactctaaaa taaaact
//
LOCUS       DAYNVV010000186          556 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.200, whole genome shotgun sequence.
ACCESSION   DAYNVV010000186 DAYNVV010000000
VERSION     DAYNVV010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..556
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.200"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..>556
                     /locus_tag="ACGXWR_002955"
     rRNA            <1..>556
                     /locus_tag="ACGXWR_002955"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          135 a          130 c          168 g          123 t
ORIGIN      
        1 catgtgtagc ggtgaaatgc gtagatatat ggaggaacac cagtggcgaa ggcggctctc
       61 tggtctgtaa ctgacgctga ggctcgaaag cgtggggagc aaacaggatt agataccctg
      121 gtagtccacg ccgtaaacga tgagtgctaa gtgttggagg gtttccgccc ttcagtgctg
      181 cagctaacgc attaagcact ccgcctgggg agtacgaccg caaggttgaa actcaaagga
      241 attgacgggg gcccgcacaa gcggtggagc atgtggttta attcgaagca acgcgaagaa
      301 ccttaccagg tcttgacatc ctttgaccac tctagagata gagcttcccc ttcgggggca
      361 aagtgacagg tggtgcatgg ttgtcgtcag ctcgtgtcgt gagatgttgg gttaagtccc
      421 gcaacgagcg caacccttat tgttagttgc catcattcag ttgggcactc tagcaagact
      481 gccggtgaca aaccggagga aggtggggat gacgtcaaat catcatgccc cttatgacct
      541 gggctacaca cgtgct
//
LOCUS       DAYNVV010000187          548 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.201, whole genome shotgun sequence.
ACCESSION   DAYNVV010000187 DAYNVV010000000
VERSION     DAYNVV010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.201"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..>548)
                     /locus_tag="ACGXWR_002956"
     CDS             complement(<1..>548)
                     /locus_tag="ACGXWR_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFK0804407.1"
                     /translation="SLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQW
                     ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPT
                     IFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG
                     NDDLLEKYMSGKSLEALELEQE"
BASE COUNT          147 a          119 c           84 g          198 t
ORIGIN      
        1 tcctcttgtt cgagttccaa tgcttctaat gatttaccgg acatatattt ctctaaaagg
       61 tcatcgtttc cctctattac cgtatcccat tgttcagatt cggtaaagtt cgtcacacac
      121 atattaggat acagttctac cttctgtttg attacaattt cggcagaaag tttctcttta
      181 atatcctgat aaaccgttga taaatcaatt ccattttggt caatcttatt gataaaaaag
      241 attgtgggaa tccccatttt cctaagtgca tgaaataata tacgagtttg tgcttgtacg
      301 ccatcttttg cagaaatcag tagaattgcc ccatctaaaa ctgataatga acgatatact
      361 tctgctaaga aatccatatg tcctggcgtg tctatgatgt tcaccttcgt attttcccac
      421 tgaaaagagg ttattcctgt ctgaattgta attcctctct gacgttctaa aagcgtatta
      481 tccgtcctcg ttgtaccttt gtccacgctt cctaattctg taatcgctcc actgttatat
      541 aataagct
//
LOCUS       DAYNVV010000188          528 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.202, whole genome shotgun sequence.
ACCESSION   DAYNVV010000188 DAYNVV010000000
VERSION     DAYNVV010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.202"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            7..302
                     /locus_tag="ACGXWR_002957"
                     /pseudo
     CDS             7..302
                     /locus_tag="ACGXWR_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            377..>528
                     /locus_tag="ACGXWR_002958"
     CDS             377..>528
                     /locus_tag="ACGXWR_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFK0804408.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWV"
BASE COUNT          199 a           63 c          112 g          154 t
ORIGIN      
        1 atgtaggtga aaaagtttaa aaagaaaata tatttaggat tggttgttgg ggtgagtatg
       61 tttgggttca tggctcatac taaacaagta actgcagata ctaaccaaaa agaaaggatt
      121 atgagccaat tagatgactc tcaaataagt atgtacccaa tgagctaatt gtcagtttaa
      181 aggctacaca aagaatttca acagagaaaa ataaaccgca aaatttattg ggtgtaaaag
      241 ttatggtgga aaaagatttg actcttagga caaatgaaag cgattgtaat aagcgagatc
      301 aagggttctg ttgcaaagtt ttccaaaaaa tctattttag tgtaaaattg agaaaaaaga
      361 cagagaggac agagtaatga atcattttaa aggcaaacaa ttcaaaaaag acgtcattat
      421 tgtcgctgtt ggttactacc tgcgttacaa tctaagctat cgtgaagttc aggaattgtt
      481 atatgatcgt ggaataaatg tttgtcatac tacgatttat cgttgggt
//
LOCUS       DAYNVV010000189          524 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.203, whole genome shotgun sequence.
ACCESSION   DAYNVV010000189 DAYNVV010000000
VERSION     DAYNVV010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..524
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.203"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(152..346)
                     /locus_tag="ACGXWR_002959"
     CDS             complement(152..346)
                     /locus_tag="ACGXWR_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804409.1"
                     /translation="MVHSTIGVVVEKSRDNLVFVTEIQTGRSFVVTDKAAKAYQSSDI
                     LTLNLTTKTFVDATEDYPFV"
BASE COUNT          163 a          110 c           79 g          172 t
ORIGIN      
        1 tgtgatagag aaataacaat ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat
       61 ttgattttga tcgggtctag tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc
      121 ttaaatttca tcttgactta tcaccattag actaaacaaa tggataatct tctgtcgcat
      181 cgacgaacgt cttcgtagtc agatttaacg ttaaaatatc gctactttga taagcttttg
      241 ccgctttgtc tgtgacgaca aaagatctgc ctgtttgaat ttctgtcaca aaaacgagat
      301 tgtctctgct tttttcaaca acaactccaa tcgttgaatg aaccatttct gcttcctccc
      361 ttctctttct tttgatataa tgtagtcgca aatcgcacca ctcaatgagt tggcggaaaa
      421 caattcattg aaaaaaagag tcctggacaa tcacgttcag gactctttta cttcttttat
      481 tcacttaaca actaacactc tgtgagtgaa atggactctt caat
//
LOCUS       DAYNVV010000190          518 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.204, whole genome shotgun sequence.
ACCESSION   DAYNVV010000190 DAYNVV010000000
VERSION     DAYNVV010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..518
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.204"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(103..339)
                     /locus_tag="ACGXWR_002960"
                     /pseudo
     CDS             complement(103..339)
                     /locus_tag="ACGXWR_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          174 a           83 c           87 g          174 t
ORIGIN      
        1 ttttctatat ttttttatac aaaaaagatg ttggtgaagt tcaccaacat caaaaagtat
       61 agagccgata gaaggactga ccttctgtct cagatttttt tgttatttca cttgaatcaa
      121 ttgattgatc aaaaaaatcc tgattttcat gttctcaaat gatttaaatc cataagataa
      181 tcgtttcagt gtcttgatat ggggaatctt ggcctctatt ttgccattag aataagggta
      241 aatcatagca ttgtaaatac cttcttcata cgttaaaagg ttttgaagtt tcgtgcgaag
      301 ttgtgcatca agtgtttcag gaagattttt taataacgcc gtttgtataa ttaagcgaga
      361 caaataaaaa agccatttat gttacactca aattgtaata cccgctaaag catacaagga
      421 gagtgaacat aaatgactta tacccatctt acaccaaacg agcttgtaat gatagaagca
      481 tattttcatc aagaaactcc ggttgctatc gttgcgaa
//
LOCUS       DAYNVV010000191          509 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.205, whole genome shotgun sequence.
ACCESSION   DAYNVV010000191 DAYNVV010000000
VERSION     DAYNVV010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.205"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..132)
                     /locus_tag="ACGXWR_002961"
     CDS             complement(<1..132)
                     /locus_tag="ACGXWR_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFK0804410.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          183 a           93 c           91 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactatta
//
LOCUS       DAYNVV010000192          507 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.206, whole genome shotgun sequence.
ACCESSION   DAYNVV010000192 DAYNVV010000000
VERSION     DAYNVV010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.206"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            11..>507
                     /locus_tag="ACGXWR_002962"
     CDS             11..>507
                     /locus_tag="ACGXWR_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HFK0804411.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDAT"
BASE COUNT          182 a           93 c           84 g          148 t
ORIGIN      
        1 ggacttccct atgaatgatt ttactacaga aattgtgcaa actctagtca ctaaaggcga
       61 tttaaatgaa ttattccgtt cgcacttaga aaaagcgata aacacactcc tacggactga
      121 attaacggct tttttagatt acgaaaaata tgatcgcact ggttttaatt caggtaattc
      181 gagaaacggt tcttactttc gatcaatcaa aaccgaatat ggtgaattaa cattggaaat
      241 acctagagat cgtaatggtg agtttaaaca acaaacttta ccagcctaca aaagaacaaa
      301 cgatacattg gaaaccacta ttatccattt attcgaaaaa ggtgttacga tgtctgaaat
      361 tgctgatttg atcgaaaaaa tgtacggtca tcactatact ccacaaacca tgtccaacat
      421 gactaaagtt ctgactgaag aagtaaatgc ctttaaatcc agagccttaa atgataagta
      481 tgtcgctatt tttatggacg ctactta
//
LOCUS       DAYNVV010000193          475 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.207, whole genome shotgun sequence.
ACCESSION   DAYNVV010000193 DAYNVV010000000
VERSION     DAYNVV010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.207"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
BASE COUNT          156 a           96 c           71 g          152 t
ORIGIN      
        1 ttaaatcatt tgagaacatg agaattagaa tctttttgat caatcaatta atcaatgtaa
       61 gataacaaaa aatctgagcc agaatgtggt tcattctgac tcagatttga ttttgcacaa
      121 ctcatcagtc cttattgaca aagagccaca aaagtcttgt cgcagtccct tattccaaat
      181 aaacggtgtt caatcatctg accctcggta ttagctcaaa aaacggcaaa atatgaggaa
      241 ctattttcca tttgtttctc taatactcag gacaaaacgc tgatttcaca acctccgata
      301 tacggtgttc cagaagtagc ttcttcgaaa aataagctga gatttcacaa aaatttgaga
      361 agcaattttc gtaaattcct tcttatgtct tgaagctgac cacttctgtc ataacctctt
      421 tttactgttc ttaaacacgg ataaacatcc gcatctcatt ttatgagtgc ttaga
//
LOCUS       DAYNVV010000194          436 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.208, whole genome shotgun sequence.
ACCESSION   DAYNVV010000194 DAYNVV010000000
VERSION     DAYNVV010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.208"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(178..>436)
                     /locus_tag="ACGXWR_002963"
     CDS             complement(178..>436)
                     /locus_tag="ACGXWR_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFK0804412.1"
                     /translation="KYSKACASLDDGFEDAFQYTVQGNSHNRLKSTNLIERLNQEVRR
                     REKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT          151 a           58 c           76 g          151 t
ORIGIN      
        1 atcgaaaatg gtagaaaaga aatttataaa aggacttata aagattgatt atataatata
       61 tgaaaagcta ttataaaaga cattagtatt aaatagttta aaaaaatgaa aaataataaa
      121 ggaagtgagt caattccaga ctcctgtgta aaatgctata caatgttttt accatttcta
      181 cttatcaaaa ttgatgtatt ttcttgaaga ataaatccat tcatcatgta ggtccataag
      241 aacggctcca attaagcgat tggctgatgt ttgattgggg aagatgcgaa taatcttttc
      301 tcttctgcgt acttcttgat tcagtcgttc aattagattg gtactcttta gtcgattgtg
      361 ggaatttcct tgtacggtat attgaaaggc gtcttcgaat ccatcatcca atgatgcgca
      421 agcttttgaa tatttt
//
LOCUS       DAYNVV010000195          419 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.denovo.209, whole genome shotgun sequence.
ACCESSION   DAYNVV010000195 DAYNVV010000000
VERSION     DAYNVV010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.denovo.209"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..>419
                     /locus_tag="ACGXWR_002964"
     CDS             <1..>419
                     /locus_tag="ACGXWR_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain containing protein"
                     /protein_id="HFK0804413.1"
                     /translation="TFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIYNYHG
                     WEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEEGGAS
                     SLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT          164 a           55 c           82 g          118 t
ORIGIN      
        1 tacatttgtt tttaagaaaa aagtagtttc agactattta aataacgaag gcggctacaa
       61 atatcttgca cataaatatc aaataaatcg tacactggtt agacattggg taaggattta
      121 taactatcat ggttgggaag gcttggttgg aggtggcaaa agctacacta caaaatttaa
      181 acttgatgtt atagaatata tggaaacaaa tggtctttct atccaagaaa ctgctaaaaa
      241 atttaatatc ggttcaaata gaactctaag taaatggata gagcaatatg aagaaggcgg
      301 tgcttcttca cttgagagcc aaaaaagggg cagaaaaatt agtatgaatt ccaagctaaa
      361 cattcctaaa aaacttaaag atgagtctct tgaagaagaa gttattcgtt taagagcag
//
LOCUS       DAYNVV010000196        20862 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.guided.049, whole genome shotgun sequence.
ACCESSION   DAYNVV010000196 DAYNVV010000000
VERSION     DAYNVV010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.guided.049"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            267..1304
                     /locus_tag="ACGXWR_002965"
     CDS             267..1304
                     /locus_tag="ACGXWR_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HFK0804414.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(1393..1716)
                     /locus_tag="ACGXWR_002966"
     CDS             complement(1393..1716)
                     /locus_tag="ACGXWR_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFK0804415.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(1703..2410)
                     /locus_tag="ACGXWR_002967"
     CDS             complement(1703..2410)
                     /locus_tag="ACGXWR_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFK0804416.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            2496..2837
                     /locus_tag="ACGXWR_002968"
     CDS             2496..2837
                     /locus_tag="ACGXWR_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HFK0804417.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(3008..3856)
                     /locus_tag="ACGXWR_002969"
     CDS             complement(3008..3856)
                     /locus_tag="ACGXWR_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HFK0804418.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            4454..5317
                     /locus_tag="ACGXWR_002970"
     CDS             4454..5317
                     /locus_tag="ACGXWR_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFK0804419.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            5417..5899
                     /locus_tag="ACGXWR_002971"
     CDS             5417..5899
                     /locus_tag="ACGXWR_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFK0804420.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(6162..6629)
                     /locus_tag="ACGXWR_002972"
     CDS             complement(6162..6629)
                     /locus_tag="ACGXWR_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFK0804421.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            6752..7603
                     /locus_tag="ACGXWR_002973"
     CDS             6752..7603
                     /locus_tag="ACGXWR_002973"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFK0804422.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            complement(7854..9812)
                     /gene="nagE"
                     /locus_tag="ACGXWR_002974"
     CDS             complement(7854..9812)
                     /gene="nagE"
                     /locus_tag="ACGXWR_002974"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HFK0804423.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(9809..10681)
                     /locus_tag="ACGXWR_002975"
     CDS             complement(9809..10681)
                     /locus_tag="ACGXWR_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFK0804424.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(11023..11895)
                     /locus_tag="ACGXWR_002976"
     CDS             complement(11023..11895)
                     /locus_tag="ACGXWR_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFK0804425.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            12023..12592
                     /locus_tag="ACGXWR_002977"
     CDS             12023..12592
                     /locus_tag="ACGXWR_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFK0804426.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12659..13396
                     /locus_tag="ACGXWR_002978"
     CDS             12659..13396
                     /locus_tag="ACGXWR_002978"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFK0804427.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            13627..14895
                     /locus_tag="ACGXWR_002979"
     CDS             13627..14895
                     /locus_tag="ACGXWR_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFK0804428.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            15382..15846
                     /locus_tag="ACGXWR_002980"
     CDS             15382..15846
                     /locus_tag="ACGXWR_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFK0804429.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            15830..16459
                     /locus_tag="ACGXWR_002981"
     CDS             15830..16459
                     /locus_tag="ACGXWR_002981"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFK0804430.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            16813..18291
                     /gene="msr(C)"
                     /locus_tag="ACGXWR_002982"
     CDS             16813..18291
                     /gene="msr(C)"
                     /locus_tag="ACGXWR_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFK0804431.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            18338..18784
                     /locus_tag="ACGXWR_002983"
     CDS             18338..18784
                     /locus_tag="ACGXWR_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFK0804432.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(18983..19498)
                     /locus_tag="ACGXWR_002984"
     CDS             complement(18983..19498)
                     /locus_tag="ACGXWR_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFK0804433.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            19615..20816
                     /locus_tag="ACGXWR_002985"
                     /pseudo
     CDS             19615..20816
                     /locus_tag="ACGXWR_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
BASE COUNT         6631 a         3703 c         4315 g         6213 t
ORIGIN      
        1 caaggagcaa tttcaaaaaa cagcttctca tgtttgatga atattttgac ttgtgaccga
       61 agagttggta ggagaacacc gtttataaga ggttgtgaca aaagtcttgt cgcaacctct
      121 tttttaacca aaaaagtgca aatagtttac tttaagtaag agaataatta tgatgaataa
      181 aaaaggtgga acaaatagca tactatatat attgaaatga acactgtatg gatgctccaa
      241 cttgatgaag ctaaggagga attcgtatgt cagaaaagga attaatgaag gtagtcggtt
      301 tttatgaagg gttgccgatc gatgatccaa aaagctttat tgatgaaaaa gaacagatac
      361 ctgtacccag ttcacgggat cttctggtaa aagtcaacgc agtatctgtt aatcctgtcg
      421 atacgaaact tcgccaagat aacgggataa gaaatgcttt acgtatctta ggttttgatg
      481 gagtcgggaa agttgttgct gtaggtgacg aagtgcaaaa attttctgtc ggcgatcgcg
      541 ttttttacgc aggtacaaca acaagagcag gaagcaatca agaataccaa ctagttgacg
      601 aacgtattgt cgctcttgca ccaaaaaatc tttcagatga agaagctgca gccttgccgt
      661 tgacctcatt gaccgcttat gaattgttat ttgaaaaatt tggtctaact ccagaagaaa
      721 atgccaatcg cgggaaaaaa atcttagtga tcaacggatc cgggggcgtc ggttcgattt
      781 tgaatcaact agcgcattgg gctggcctag aagtctacgc gactgcaagt ccgaagaatt
      841 ttgaatggct gaaaaaaaca ggtgtagact atccaatcga ttatcatcac gacttaagta
      901 aaagttttcg tgaattagga atcgatcaag tagagtatgt cgctgtatta ttcgatatta
      961 cccgctactt tgatcaaatc aagcaccttg tccgaccatt tggacatgtg ggaacgatcg
     1021 tagggatcaa agagccgtta gatataggtg tttggaaaaa ccaatctatc agcttcgact
     1081 gggagtatat gttcgctaaa acagactata actatgaaat cgaaacgcaa ggagaagctt
     1141 tagcgcacat tgctgcttta gcaaatgaag ggattatccg cagtacattg agcaaggtct
     1201 attcagatgg gatgaatgcg aagaacttga aacaagcaac caaagacgta gaaacaggac
     1261 atatgttagg aaaagtcgtt gttagtggtc cgttcaacgg ataagcaaga atacgccgat
     1321 ttttttctta tttgactttg ataaaaacaa gagcgcatga cagtaatttg ccataagctc
     1381 ttgttttttt atttataata agcgaatcaa cgaaagggaa agaattcctg ccaagacgat
     1441 caccaataag ctttttgaaa gaatagcagc taaaagtgta ggaactgaag ccaaagcatt
     1501 ttcgagattg atctgcggca gatgtccgat attttgggta aatagactgc tgaaccataa
     1561 agcagacata atgacgatcg ggacaaaact taaatactca agcaacggtt gcggtaaatc
     1621 gaattttttc agtaagacaa atggtaggac cctagaaagc caagttgcta aagtacaacc
     1681 taaaatagtc agcaatgtaa actcaaaaga aggcatgttt gatccacacc cccaatccgc
     1741 acccaatcag tgttacaact acaatcacta agttgcttgg gataaaaatc agtccgacat
     1801 ataccagaat caaagtgaga ccaatcagga tcaactgtaa tcgtttagag gtgtttctat
     1861 cagaaatgac ttgaagataa agtaacccga taaacatagc gacgatggcg aaatccaaac
     1921 caaacttttt cggatcagta ataaaattcc ctaaaagtgc gccaacaaga gaagaaccca
     1981 cccacgtcaa ataagaaatc caattagctg tattcatcca acgaaagttt aacttttgtc
     2041 cagtatagtt caatttattc attcccagtg cgaaactttc atctgtcagc aatgtgccaa
     2101 tcagcagatt ttgaagcagc cgatttttct tgaaataagg agcaatcgtc atactcatca
     2161 gaatcattcg ggaattgact agaaaggtcg agaaaacgat ggaaagcaat gggctgtgac
     2221 tagcaagcat gctgactgtg ataaattggg cagaaccagc atagaccagc agggacatca
     2281 acgtgacgac tagtggatga aatccggcag ctttcccaac gataccaaat gcaagtccaa
     2341 taccgatata accgaaaacg gtaggtaacg tgtctttgat cgcagttttt atatctaact
     2401 tttcatccaa taacaaaact cctttagcac gacataaatt ttcataattg tcgttaaact
     2461 tgtgaatatt ctaaattttt aatgagcatt tgtcaatggt gggattgaaa cgtaaagaac
     2521 tagcgggtcg cagatttaca cgtattgttt cggtgggagg aggcgcgaaa aatcttgcat
     2581 ggctacaaat ccaagctgat attttcgatg caacggtcta ttgtttaagt atggaggaag
     2641 gacctgcatt aggcgcaaca atgattgctg cactagggtt agggtggttc gacacacctg
     2701 aaagttgttg tcagaatttt atccaatata cagatgcagc ggaacctctc ttacaaaatg
     2761 tagaaaagta tcataaaatc tatcaacaat gccggaaaat ctatccagca acgaaggaaa
     2821 tttgtcatga cttataaaac aaaacgcgta cctaatagtc aaatgactaa tattgggtac
     2881 gcgttaagtc ttctttactt catcctttgc atgattcgtg tttttaaagc aaggtctgct
     2941 gtatttcttg tggatttagg atggttgtta tcgtttactt gctatttttc attgaaatcg
     3001 tctttcttta ccgtttcttt agttttttat ctattttttt cttttggtta gaaaattctt
     3061 tttcccgaaa gtcttctttc aggattttta tagagtagcg ttttgaataa gaggcgtcag
     3121 tatgatcgac ttggcagacg aaccaagaga acatttgcct tttttctgca tgaggtgctt
     3181 ctgctaataa ttctttccat aaataataac agtcctctat cagaagaagg gttcgttcat
     3241 cctcaggctc ccaatagaat gtttcgagag tagcaatcac ttcattgatc aattcgaatg
     3301 cgggaagata ggcattttgc tgaataagcg attcaactgc ttcttggatg aactttcgca
     3361 tctccatgat gaacttcgct gttttcctgt ttttgttttt cttgataata tgatcgtatt
     3421 tatggatgat agttgttaat ttatctgaat aatttattgc atgaaatggc atcttaactt
     3481 tgaagcgttc gataaagtgc ggatgttcta taagaatctc tgttaaaagc tcccgtacaa
     3541 gagaggaact agcggaggaa acaagggacg agagttcgga aagtgagtag ttggattttt
     3601 ttattggacg ttcttcgtaa gcgaataaga cagcagccat gtgtttgcat ttttttcctt
     3661 ctatggcata tagacaatca caagtcatgt tggtcttttc atcccaagtg atcactacct
     3721 tataatcttc cgtgccagaa actgttgcgg acaagtactt gcttgtatag ttcaaatgac
     3781 ggacaaaacc gtgcagatga tagctgtaac cgcgttccaa aacgttttca ggaaaatact
     3841 caagccaatt attcatctag ttctcctttc atgaaacact tatttatatt tagtataaag
     3901 aaacgtttaa gaaaaaagta gctgatttta catatttgat aatcactttt gctcgaattg
     3961 tcaaaaattc attctccttt tcttttctta gagaatgtga gaaaaagtaa aagaatagcg
     4021 tgttttaaag atggaacttt ttttgttttt tatttatctg acaaaaatga agtgattttg
     4081 ttagaaataa ataattgttc caattgataa aagaggtatg atgtatcgca aagaaaaatc
     4141 caagcagcgt tctgatcagc agtttgaaca acaatttgct ttgtacagta ggtagtaagc
     4201 ggattaacta agggaataaa agatattttt accgctttgt ttacttagaa tctgtcttcc
     4261 ccaaaattta tttttctaaa ggtaaaacat agataggcag ataataccaa ttatccgtta
     4321 cgaaacgctg cttgagaatt ttctttagat ccatacaaca ttttctacat ctgactaaat
     4381 tggttcctga ttcatcaagt aattgacttt ctttgataat atgataaaaa ggcaatcaag
     4441 gaggaagata aatatgctta aagatctgaa ccaattgatc gattacatcg aagaacattt
     4501 gacagaagga ctttcctata aaataatagc cgaaaataca ggaatctctg aatatcaatt
     4561 aaaacgcatc tttacgttta ttgcagggat gtcgctaatg gactatatca aaaaccgtag
     4621 attggctttg gctaatcgcg atcttctaga tggatcaaga gtgacagaaa cggcgtttag
     4681 atatggatat gaaacagtcg aaggtttttc aagagctttt cgtgattggt caggatatct
     4741 gccttcagaa atcagtagat acggcataca aaaatctttt ccacgcttga cattttttat
     4801 tgatgtcaga ggaggaaaat cgatggaatt tcgtatcgaa aagaaagaac agttttatgt
     4861 ggcaggtgtg gcgaaaaaag ttcctgtcaa atttgaagga gtcaatcaag aaatacaaaa
     4921 gttagcgcag acgatcacgg agactcaaag ggaagagatg cataagttag gagatttata
     4981 tccaaatcaa gtaatcaacg tttcttatgg atttgatgga gaccgcttgg aagaaaaggg
     5041 cagtttgatg cacatgattg gctttgctac gacaaaagaa aatccgtacg ctgatttaga
     5101 aatgcttgct atagaagaac acacttgggc catttttcct aataaagggc catttcccca
     5161 aactttacaa gatacttggg ggaaaatcta tgcagaatgg cttccttctt cagattatgg
     5221 gttagtcgaa gctcccgaga tctcttttac aaaatgggga gaggatttca gtaatgttta
     5281 cagtgagatt tggattgcag tgaaagcaaa aaaatagtta aaaaataaaa atatccctag
     5341 aaaaaagagc gtaatcgtgt catttccctt taattttatg taagatgaac ttaatataat
     5401 agaaagggtg ggagaaatgg caaagtatag gatcgaagaa aaaccagatt ttacggtgac
     5461 gggtattggt gtggaattga agagtagcaa tacggatttt gtcggtttgg ctgcagagaa
     5521 acaagcattt gagcaaaaag ttatcggtaa tggaacaata gatgcattga aacaagctgc
     5581 tgaaaatcat tatttcttta cagtcaacga accctataac gggaaaatga tgtactatgt
     5641 cggtgttcaa acgagtcagg atgttccaaa cactacgcga atcatcccat tcccaaaagg
     5701 aacgtatctt gttgtaagcg ctttagcaga atcgcctgaa gaattaagaa atgatttgac
     5761 gaatacggcc tttgggcatg ttttaagaga agtagaagat tacgcctatg ttgggggtcc
     5821 aaatgctgta gtcgaaatgg gagttaccaa cgggaaatat atgggagaaa tctggatacc
     5881 ggtagtcaat aaaccatgat aatatagagg tcgtgaaagt agcgctttga cctgagcatt
     5941 agagaggaaa aatgggaaat agctttccat attttgcatt tttcagaact aatgccgagg
     6001 gtcagctact tgaacaccgt ttatcaagac gtcatgactt cagcgctttg acctgagcat
     6061 tagagaggaa aaaggggcat gacaaggctt ttgtcccccg gagaataaaa gaatttatgt
     6121 agacgattcc gatcagaaaa atgcaggcac agtagagaga attataaaaa tctctctacg
     6181 aggcctgtgt tttctggtct tttttctttt tccaaaacgg ctattttatg tatcagacta
     6241 tcaagtgtga tcttagccat ttcttcttct gcctttttct gcagccgagc gtagctttct
     6301 tctaaagctt cttggatatt cgcaccaacg acgcaatttg gatttgtttt tggatcgact
     6361 tggataagct gtgtattacc ttcgatgctg cgatagacat ctagtaaaga aatctgatct
     6421 ggacttttgg caagggaagg ctgcggtttt ccggtttttg taaagatcaa accggatttt
     6481 ttgagctgac tcatgatttt acgtacattt gctgcatttg tttcgatact actggcaatc
     6541 atctcactag aaagtgatcg ggtatcttga aacatttcaa tataggcaag tacatggatt
     6601 gcatcactaa attgcagaga atacttcatc agttgtcatc ctttcatttt ttttgcttga
     6661 cttatcttac cacactcttt atgataaagg tgtaatttat aaatgtacag ctgtaaatct
     6721 taacaaataa aaagaatagg gagtggcaaa tatgcattat ttagtaacag gagcaactgg
     6781 aggttttggt ggttatgcgc tggaattctt aaaaaagatg gttccacaaa atgaaatcta
     6841 tgtactagta cgtagtgaag aaaaaggaga agcactgaaa gaagctggat ttaatatacg
     6901 tattggtgat tatgatgatt tagactcaat gaaagaagcg ttgaaaggaa tagatcgatt
     6961 gctttttgtc tctggcgttc caggaaatcg tcaagccgaa cataagaatg tagtgaaggc
     7021 agcacaagca gctggggtat cttatatcgc ttatacaagt tttgcagatg ccgatcactc
     7081 gatcagtgta ttagcgccag atcaccaatt cactgaaaaa atgattaagg attcaggtat
     7141 ttcccataca tttttacgga ataattggta tgtagagaat gaattaccta tcattgggca
     7201 ggctttaaaa actggtcaat tcgtttatgc tgcaggaaat ggaaaaacag gttgggcatt
     7261 gaaacgtgaa tatgcagaag ctgcagcaaa agtactagta gaaagtgact ctccagaaat
     7321 cttagaatta tccggcaatc taactgacta tgaagaatta gccaaggcat tagagcgtgc
     7381 gacaggtaaa gagttagaaa ttattgaagc aagtgatgca gcgtttgtcg aaaatctaaa
     7441 agaagccgga ttccctcaag aagcagctga catgttttta gcgatccaac atgatattaa
     7501 aaaggatcag ttagctattt cctctgatga tttagaaaaa gtattgggaa aaccattaac
     7561 ttctcttgaa gcagcattaa aagaaatatt ggatcaggaa taatgtataa agaggttgtg
     7621 aaaaagccga ttagttttga gtatgaagaa aaattttgtg aaaaagctgt tctgcatcaa
     7681 gtaataagaa gagtcaaata aaaaatagct cttcatatgt ttcgtttagc tggacttatt
     7741 accgcggagt tggcaggaga acgccgtttt tattcggaaa aaggagctga gacaagattt
     7801 ttgtctcagc tcctgtttgt ttatcgataa aaaagtctgg ggaagacgat ggctcaggct
     7861 ttgttggaaa cagagccgat tttatcattt gcttttacat cacgtgcggg ttcgatttct
     7921 aagctttgga ctttgtcgcc atttgtgaat acaacgacca tatccgtgtt tttgcctgca
     7981 gattgaatag cggcaagatc aactaaagca atcaattgac ctcttgcgac tttttgacct
     8041 tcttctacat ataaagtgaa tggttcgcct tttaagtcaa cagtgttgat gcccatatga
     8101 agcaagactt cgataccagc atctgtttgg attccgacag catgtttcgt tgggaaaatg
     8161 tttgtgatcg taccagcgat tggagagaag atttctccat tttctggtaa tacagcatag
     8221 ccgtcaccca tcattttttc cgcgaataca tcatctgaaa cttcagtgat tggaatcagt
     8281 ttcccatttg cgatagcgta aatatcttgt tcgatcgttt caccggcaaa tgtttctgtt
     8341 ttaaccacgg tgtttgtttg tgcaggtcgt gctgcagcac caccatgtag ttttgccatc
     8401 tcatctgcaa cgaattgtac ttctgtacct acgatgactt gcgcattttt tccgtcgatg
     8461 atcttcatac caggtacgcc agtggctttg attttatttt gatcgatcag gcctgtatct
     8521 ttgacttgca aacgaaggcg tgtagtacag ttatcgatcg aagttacatt gtcggctccg
     8581 cctaatgcag cgtagatttt gcttgcttgt gccgcatatt tattgtctga attagtcgtt
     8641 gcagtatcgt catctgaaag atctgcttcc tcgcggccag gagtcatcag atggaatttt
     8701 ttgatagcaa agttaaagcc aaagtagtaa atcactgctg ttactaatcc ttggacgatc
     8761 aacatcaatg gctgattcgc aatcggattt ttcaaagata ggaagtaatc gacaaatccg
     8821 gcactaaagg caaatcctgc tgtccaatgg aagaatgcac tcactgctaa agaaatccca
     8881 gtgaaaattg catgcaagac atataatggc caagcaacga acataaatga aaattcaagt
     8941 ggttctgtca caccagtaaa gaatgaagca aaagctgctg ctagcatcaa ggaagctgtt
     9001 tttgctttgt tttctggacg tgcatttctg taaatagcat atgctcctgc tggaagcccg
     9061 aacatcatga ttgggaaaaa tccagcttga tacattcctg ttacgccttt tgttccttca
     9121 gaagccaaaa atttaccaat atcattgatt cctgctacgt caaaccagaa cacggagttc
     9181 attgcttgat gcaatcctgt agggatcagt aaacggttga agaagccata aagacctgca
     9241 ccaccccagc ctaaactcaa aatgaattta gcaaaagaaa ctaaagcaga gtaaaccgga
     9301 ggccatacga gcagtagcac tgcactgatc agcaacatga caaaggcagc caagattggc
     9361 actagacgct tgccgctaaa gaaagataaa gccatcggta attttgcttc gtggaaacga
     9421 ttataaagag ctgccgcaat caatccggca ataataccaa taaatacgtt actgatctga
     9481 gcaaaagatg gatcaactga ttctggtttg atattcaata aagtagctac tgaatcagtt
     9541 tttaaaacat ttactggaac ttcaaatgcg accaaacctg ccaaggcagc agcacctgat
     9601 ttgtccactg acatccctag tgctaaccca acggcaaaca gcaaaggtaa ttgacctaaa
     9661 actgcgttac cgccagcttg taaaaaatga gcgacaatgt cgttactata agatgcccac
     9721 cagtttccga tccctactag taaagcagca gcaggtaaga ccgcaactgg aagttgaagg
     9781 gaacgtccca ttcgttgtag atatgctttc aatttttttc ctcctcatga ttgttaacat
     9841 ttgtttgtac gattgcgctt cttaaacgct cgatatggat ggccaagtaa cccagttctt
     9901 ctttcgtgat cgcgagctgg tattctttgg tcagcaacac acggattttt ttagaaatct
     9961 tatagctttc tgggtatttt cgtttgacca tttctacgat ttccgtgtct aaaacagcat
    10021 attgttgcgc atgggttcgt tgtagaagca gtcgtaaatg attcaccagt cttgaataat
    10081 tcagtgaaaa tggttctgaa tggatatctg tttccaattc tgattccact aaatggatga
    10141 tgtcagatac aatcgtcact tcacggatac tgcgatggtt attgttccga ccgcttcgtc
    10201 cgctgtgaat atggattgcg atatatcctg cttcgtcata agtatatgga atcccaagct
    10261 cttttgtcag atactctact gcccattgag caatactgaa ttcatcactg taaagcactt
    10321 cgatttctct taaaagtttg ttgcggatga cgataccgtt attaatgttc tccgcagaaa
    10381 aagcaatgtg gtcggtcaaa gcgatcaata catgttcatt caacttttcc atcaaaacag
    10441 tttccgcatg atcaatgatc gtttctgctg caaataaaaa gcgttcatca atctgattaa
    10501 gtaaattttg caacttgatt tgaccttctg gttccatgac aaatatccgt tcgacatcac
    10561 gatcaaaaat caaatcattt ctttttctgt caaatccaat cccttttcca atagctactt
    10621 tttcctgtcc accgtcatct accaatactg cattttgatt aaagatcttt ttgattttca
    10681 tgcgcgcacc ctttttgaag atttggtttt cacgtttgct agaccagttg attgcggcca
    10741 aacaaaaata gacacgaaaa acctcctagg gaaaccatgt tcctcagaga tttttcatgc
    10801 ctagtatgat ctagtcacat gaaacgaatt attgttaacg taatcaattt tatatagaca
    10861 gttatgtttt gtcaattctt tttttataat tatagtaatt tactggaatt atcagaaata
    10921 aaaggaagaa ataaattaag aaacttatgt tatttaatcg ttggatcttt tgcttatctt
    10981 attcgttgtt aaaaagctga aagcgaagga aaaaaactct acttaactgt atttctccgt
    11041 taggacatct aaaaatttac gagcagcagg agaaagaggc tggtcttttt tccaaatgag
    11101 attcagtgaa gcttgtaatg gcggatcgag tgggatgaat attttttccg tcccataagt
    11161 attgatgatc ccatctagag ctaatgcacc aaaagtcccg ttatcgacca tcaaagaagc
    11221 attgtacaat aagttatatg ttccgacgat cgataactga tctatgctga aacctagcca
    11281 ttcagctagt tgactgtcca ctgacgtttg ccgggaaatg atcaaaggaa cagttttcag
    11341 ttcctgcgga tggatgacgg tttgctttgc taaaggatga tttcgatgta tcaaaagtcc
    11401 ccaacgatct tgggctggca gtcgaaatga ctggtatttt tgtttgtttg tcggttcgat
    11461 tacgagtcca aaatcaagta atccgctatc cagtttgtct atgatatcat ctgcattccc
    11521 gctatataaa tgaaactgga tatcaggatg cgccttgatc aacgaatgaa ggctatcaga
    11581 aatgaaagag attgctttag tttcgcctcc gccaatgtag atttctccag agatgattgc
    11641 gtcatttgtt aaattgttcg ccgttttttc taccaacgac aagatttctt ttccttttga
    11701 ataaagatat cgaccagaat ccgtcaactg tatctctcgg gagccccgag tgaaaagtgt
    11761 cacaccaagt tcttcttcta aatctttcag ttgttttgag agagtaggtt gcgtgatatg
    11821 cagagatttt gctgctcggc tgatattttt ttctctagct actgctaaaa aatacgtcag
    11881 tatacgaata tccatttttt ccctcctgtt tttaaaaaag cataccacta agtatagtta
    11941 aaaggaatag ttaagtatgt tttataagta ttagacatga taagccgtcc gttataaagt
    12001 aaggataaaa ggagggagca aaatgacaag cctcatcgaa aaacaaatcg tcaataaaga
    12061 gattcgagta acggatccgc tctttgaagt gatccatcag atccaagctg aaaacgaaga
    12121 gcctttagca gcgctgaata ctgggtacca tgaaccagca gatatccgca aacggctaga
    12181 aaatatcatt agtgacaaag tagatgatac ggtgactgtt ctgctgcctt tttatacaga
    12241 tttcggcaaa catattagta tagggaaaaa tgtctttatc aatcgtcaag tgatgttcgt
    12301 tgacttaggt ggcatctgtt tagaagattc agtattgatt ggtcctcgtg tcaacctcat
    12361 cacggtgaac catctaaccg atccaaaaga acgaagaggc ttgtcagtaa agccaatcca
    12421 catcaagaaa aatgcttgga tcggagcagg agcaactatt ctgccaggcg taacgattgg
    12481 cgagaatgcc attgttgcag cgaatgcaac tgttacgaaa gatgtcccag acaataccat
    12541 cgttgcagga atccctgcca aaatcgtcaa acctgtcgaa cggattattt gaacagtaag
    12601 atgaaataag agatagtgag tataagcaag agatttttca aaacaggagg agaatagaat
    12661 gaatgattta tcagaaaaag tgattgtcat catgggcgct tcaagcggaa tcggtgaagc
    12721 aacaacgaag ctattagcag aaaaaggggc taaactagtt atagctgcac gccgagaaga
    12781 tcgcctaaaa gcaataaaag aatctttacc agaagctgag ctatatattc aaacagcaga
    12841 tgtaagagat tttgcacaag tccaagcagt tatcgattta gcgatggaaa agttcggtcg
    12901 aatcgatgta ttgtacaata atgcaggaat catgccaacc gctccattag ttgaaggtca
    12961 ccgtgatgaa tggcaaaata tgcttgatat caacatcatg ggtgtgttaa atggaatttc
    13021 cgccgtactt ccaatcatgg aaaaacaaaa atctgggcat atcatttcaa ctgattctgt
    13081 ggcgggacat gttgtttatc ctgattccgc cgtttattgc ggaacaaaat ttgctgtccg
    13141 tgcaatcatg gaaggattac gtcaagagca acggcaaaat aacatcaaat ctacgatcat
    13201 ctctccagga gctgttcaaa ctgaattata tcaaaccatc agcgacaaaa aggctgctct
    13261 tgaacttcat gaagcgcaaa aagaatgggg attgacctcc gaagatatag cttctgctgt
    13321 agcatttgcg atagaaacgc cagaccggat gtctgtcagt aacatgatta tccgtccgac
    13381 gacacaggaa gtataatcca taacggataa tatccaaaga gaattacttg ttaaatagtt
    13441 attcaaacga ccatcaattt aaggcgtgaa tggagaagaa tattcttcat ttacgtcttt
    13501 ttatgtagaa aaagcaaatt tatcaaaaag aaacaaatgt tatttaaata tggacattga
    13561 cttgctttta cttttttagt tacactgtta tttaggaaaa gtttcataat tcaaaggaga
    13621 aaaaagatga aagcaaagaa tttattattt agcgttattc ttttaggaaa tctagcagtt
    13681 gccaacacaa cagtgctagc tgaagaatcg acagaaactg tcgcaactca gacatcgagt
    13741 tcttcagaaa caggaattga aaacgataca gagagtactt tgcagtcagc tactgtctca
    13801 gaaaatacaa tttcaaccga agaaccaaca actgaaacaa cagaacaaac acaaaccgaa
    13861 gacagtacat cagcagaagc tcagaacaat ccagagaatg cagaagaaat cacgaaccaa
    13921 ttgacagatg ggcaaacatt gacacatacc catcaagcag atttgtctga attcgaaaac
    13981 tatactggct atgcttttta tgctcgctca tctgctaatt ctcaacaagc gttcattgat
    14041 agtattgcct caactgcaca aagtttggca agtgccaatg acttatatgc atcagtcatg
    14101 attgctcaag ccatcgttga aagtggctgg gggaacagta ctttggcttc tgcccctaat
    14161 tacaatctat ttgggattaa aggaagctat aatggccaat ctgttacgat gcctacttcg
    14221 gaatatgtga atgggcaatg gattacggtg aatgccgctt ttagaaaata tccttcgtac
    14281 aaagaatcat tgcaagataa cgtaacggta ttgaagacga cttcttttca gccaggcgtt
    14341 tactactatt ccggtgcatg gaaaagcaat acgaactctt acaaagatgc tacggcttgg
    14401 ctaacaggtc gttatgccac tgcgcctaat tatggttcta cattgaacaa tgtaatcgaa
    14461 acctataatc tgacacagta tgatacagca ccaacttcaa cttctccgat gtatcgtctg
    14521 tataaccgtc atacaggaga acatttatat acattgaatg ccggagaaaa aaattatctg
    14581 ccaactgtag gctgggaata tgaagggatt gcttggcaag caccaaacag cggacaacct
    14641 gtctaccgtt tatacaatcc ttacagtgga gaccatcatt acacaatggc acaatctgag
    14701 atcaactctt taacaaaaat cggttggcgt tatgaaggtc taagttttta ttctggtggt
    14761 tccaagccaa tttatcgact atttaatcca aatgaaaaaa ctggtaccca tcactatacc
    14821 ttgagtgcta aggaaagaga ttggctaaca ccgatgggct ggagatatga aggaatagga
    14881 ttttatggtt attaaaaaga ggtagtgaaa aagctgccct gcatcaagta gtaagaacag
    14941 ccaaacaaaa acagattttc atgttttttg tttggttgaa cttattaccg cagatgcaag
    15001 tttttgaaca ccgtttactc aaaaaaggtt gtgacaacat cttgtcataa cttttttatt
    15061 actgtttaag catactgatc caatttctaa tattcgacgg gattcttgca aaaggcgatt
    15121 tcggaaattt ttggcggtgt aaaattttct actgcagaag agctatcttc tatagtttga
    15181 taagaatcaa taatcttggt tttagcgttg tgctttcttt atcatttttt ccgttcattc
    15241 tacaaaaaat ttcttttctc tatacttttc tattgagagc gtttttttta ttacacagct
    15301 gattctttga cttttttctt tttttattct attattgaca agtcaatcgt tgacgagtca
    15361 attattagaa aggaggaaat tatgtcttta gaagagatta gtcacctttt atatcaaatc
    15421 aaattagccg atcaaaaaat cgtccagatc tttgaagaaa atatcggtat aagtcttact
    15481 agatacgaga tcatgatgag actgaaagaa gaaaatccat tgctacaaag cagtttgcaa
    15541 gaaaagttgc agattgatca aggagcagtt actcgtcatc tgaaggtatt ggaagcaaat
    15601 ggctatgttt cgcgtcagag aaatcctcag aacaaccggg aagtgtatgt agcgctaaca
    15661 gaaaaagccc agaagaaaat cgagcattgt gaaatggacc ataaagatac aggttccgtg
    15721 ctatccccgg ctttcagcga tgtagaaatg aaacaatttc taacactttt agataaattg
    15781 aatacccaac tttgcaatat aacaacagaa acgaaagagg ttaataataa tggaacaaaa
    15841 aaatgatttt tcaacaatta tgactggtag aagatccgtt cgcgtatatg atgaaacata
    15901 caaaatccca cacgaagaaa tgctggaaat gatcaaagaa gcgacgactg caccttcttc
    15961 tgtcaatatg caaccatggc gctttgtggt cgctgaaagc gaggaagcaa aagaaatctt
    16021 gcgtcctttg atccgtttca atacgagaca aaatgatact tcttctgcaa tggtcatgat
    16081 ttttggcgat atgcaatgtt acgaatatgg cgaagaaatc tataaccaag cttacgaatc
    16141 agggaagatg ccaaaagaag tcagagatca acaattagct gcgatcattc cttattacaa
    16201 gagtttttca agagaagaaa tgaacgatgt agtcaaagtc gattctagct tagcggctat
    16261 gcaattcatg ttagttgcgc gtgatcatgg ctatgaaaca aatccaattg gtggattcga
    16321 agcagatcag ttggcagagg catttggttt ggataaagac cgttatgttc cagttattat
    16381 tttatcaata ggaaaagcgg tagaagaagg ttacgagtct gttcgtttag caccagaaaa
    16441 gatcactacg ttcgaataaa aggttttcag ttactattca gtagctattg ctttttttga
    16501 atcgtgtgtg gtaacctaat aaaaaaggag gtcggaaaaa tgactgcatc gatgaaatta
    16561 cgtttcgaac ttttgaataa caactaaata aattcaaaag acatgtataa acaacaattt
    16621 catggatgga gtatgtccat tttttcgaac gacagtagaa taggtgaaag ctatgacaga
    16681 tttggtgatt tagtcatagt tatttcgttc agagtaggaa aagatgtgat gcagtttttt
    16741 tgcaaacaga tttttctgct cttttttagt atcgataatt gttgttttac atgaaatagg
    16801 agtgtaaaac atatggaaaa tttagcagta aatataacaa atctacaagt cagctttggc
    16861 aaccagctag aactatctat tgattctctt cgtgtctatc agcaagatcg tatagggatc
    16921 ataggagaaa atggtgtcgg taaatcgact ttgctcaaac taatagccgg tgaacttttt
    16981 cccgatcatg ggaaaatcca aacagagatc accttcaact acctgcctca attaacctat
    17041 ctcgctgaag caaaggacct aaatttggaa ttagccagtc atttccagtt aagactggaa
    17101 gaaacttcag agcggaaatg gagcggaggg gaagaacgaa agatcgagtt gatacgtctt
    17161 ctttcttctt atgaacaagg gatgcttcta gacgagccaa caacccatct agatagaaaa
    17221 agtattgatc gactgattga agagcttcgt tattattatg gtacgctggt ttttgttagt
    17281 catgatcgct attttctaga tgagctagca tcgaaaatct gggaagtaaa agacggagaa
    17341 atccgagagt tttcggggaa ttatagtgcc tatctcactc aaaaggaatt ggagaaaaag
    17401 actcagctac gagaagcaga gtcgatcatg aaagagaaaa aacgattgga aaaatcgatc
    17461 caagaaaaga aaaaacaagc ggaaaagttg gaaaaagtgt ccagtaaaaa gaaaaagcaa
    17521 caaatcagac cggatcggtt gtcttcctct aaacaaaaag acagtgtaca aaaagccatc
    17581 caaaagaatg cgaaaacatt agagagaaga ctccaaaaaa taggagaaac aaccaagccg
    17641 cagcagatga aacaaatccg ttttccagta ccaaaatctc ttgaactcca cagccgctat
    17701 cccatcatgg gacaaaatgt ccaattggaa agaagtggga gaacattact ggtaaatggt
    17761 gattttcagt tttctttagg taaaaaaatc gcgattgtcg gtgaaaatgg ttcaggtaag
    17821 acaaccttat tagaacatat ccgcaaacaa ggagaaggaa tccttctctc tccgaaagta
    17881 agctttcaag tatatcagca aaagggttat caaatgacat ctgaagaatc catcattcgt
    17941 tttgtcatga gacaaacaga gttttcagaa tcgcttgtcc gtagtttgct gaatcactta
    18001 gggtttgctc aggaaacttt gacgaaaccg ttatgtacat taagtggggg agaagcgacc
    18061 cgtctgacga ttgctttgct ttttactaag ccaagtaatg tgttgctgtt agatgaaccg
    18121 actaatttta ttgatatggc aacgatcgaa gctttagaga agctaatgca aatatatccg
    18181 ggaacgattt tgtttacttc tcatgattct tactttgtcg agcgtacggc tgatgaagtt
    18241 tatgaaataa aagggcagaa aataaaaaaa gtacttacga gaaattttta aatgtgctac
    18301 gatgattttc gtgacaaatt taaaggagtg gtacagattg cctacaaata aaaaagaagg
    18361 aataattttt acaacaatga tgtgtttttt gatggtcttg gggatgagcg cgtataattt
    18421 atggctgcat caagatcttc atttatcaag tttgttgatt ggtctagtgc ctggattcgt
    18481 ggtggctttc attttggatg tcttcatcat cggtgtgctg gcgaaaaaaa ttgcctttaa
    18541 actaccagta aatccagaaa gcaaggtcca aatgatctta actatttcat gcttgatggt
    18601 tttaggaatg gtgacatgta tgtctttatt cggtgtgatc atggaacaag gaatacctga
    18661 tcaattattc tctgcttata tgaatgcttg gaaaatgaat gtgattgccg ctttaccgtt
    18721 gcagttgatc atcgttggcc cgctttcaag aagtgtgcta aaagcaattc aaagtaatga
    18781 atgatggaac actgttattt gaaaaaaggc cttggcatgc tttttgtcat agtctcttga
    18841 atgcagttct agaaaaatag tgatccgaac gataggtttt ggcctgtcgt tcggatcgct
    18901 ttttcttttc caactgtatt gctcttttat tgaagataat ttgctcttca atagatattt
    18961 ctagaaaggt tctgtttatc ccttactcaa aaaactgctg catttgttct cttacttgct
    19021 gacaccattg gagttcctgc tgacaaagca taattctgcg ctggatcaca acataacgtc
    19081 caaattcttg tttcttgtct agcgagaggt cattcaattt tttttgattt ttttgcatga
    19141 ttttgttcag ctgttgttct ctagtgaata gcagtccagt agctgttgtt ttatcgagcg
    19201 tcgaaaaagc atagattttt gctagaaatt catctttttg cgtaggagcg ggagtttcct
    19261 ctttgatcca ttcctctaca agagcacgtc cttcatcagt caagtggtag atcttttttt
    19321 gagagtgctc gtctttgtcc aaaacggtca cataaccctg ctggtctaac ttggcaagcg
    19381 ttgtatagat ctgactgtga tgggcttccc aaaaaattgt gatcagctgc ttcaattcat
    19441 acccagaacg tggtttggat aaaagcacgc ataataatat ataggctaaa gtattcataa
    19501 aaatcctacc tctcgtctta ttttctttat tatatcacag taaagtttcc acgttttaca
    19561 tgtgcatatt tacatgtaaa ataaatcatg tatgatgcta atagagagaa agggatggaa
    19621 atattggaga atcaaataga tatacaagaa caaacaaatg aagaaacaaa ggggaaaagt
    19681 tcagcgctag ttgtagcagc tacctgtatg atcgctttta tgggagtggg tctagtagac
    19741 ccaatcttaa aaacgattgc tgcacagtta aacgctacgc cagctgaaac gaccctgtta
    19801 tttactagtt acatgttagt cactggtgtg gtgatgctat ttacaggttt cttatctagt
    19861 cggatcggtt tgaaaaaaca ttgatgacag gattgtttat catcgttgta ttcgctggtc
    19921 ttggcggatt atctgggaat atcggaatgc tgattgggtt acgtgccggc tggggtgtcg
    19981 ggaatgcttt atttgtctct actgctttag caacgatcgt cagtatttta gttggtaaca
    20041 cagaaaaagc aatcatgatg tatgaagcag cacttggctg cggaatggct gttggccctc
    20101 tagtcggtgg ggtcttgggc agtggttcat ggcgttatcc attttttggg gtagcatttt
    20161 tgatgttttg cggttttata gccctagcgg tacttttacc tgaaactgag aaaccaaaga
    20221 gaaaagtagg cctttgggaa ggtgtcaaag cgttaagcaa tcataaactt cgttcagttg
    20281 gactaatcgc attgttatat aatttcggat tctttacttt acttgcgtat gcgccatttt
    20341 tattgattgg ctattctgaa ttagaagtcg gttttgtatt ttttggctgg ggtgtgcttc
    20401 tggctattgc ttcgattttc gttgcaccgg ctcttgagcg gaagtttacg acttatcgga
    20461 caattttagc agcatttgtc ttattcatta tttgtttgct gttattagga gctggaactt
    20521 ctatgccagt ccttgtaccg atcagcattg tgttagcagg atttttccaa ggaattatca
    20581 atacactgtt gacgacgatt gctatggaaa taccaggtct gcaacgaaac gttgcttcgt
    20641 ccagctatag ttttgtccgc tttttcggtg gagctttagc accatttatt gcaggtgtga
    20701 ttggtgaaca tattggtgaa agctatgcgt tttattttgc aggtgccatt gttcttatca
    20761 gtgtatgttg tatcatttat caccgtaatt attttgctac aaatgaagaa gaataagaaa
    20821 tcagaggttg tgaaaaagct gtcctgcatc aagtcataag aa
//
LOCUS       DAYNVV010000197        20283 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.guided.051, whole genome shotgun sequence.
ACCESSION   DAYNVV010000197 DAYNVV010000000
VERSION     DAYNVV010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20283
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.guided.051"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..1168
                     /locus_tag="ACGXWR_002986"
     CDS             <1..1168
                     /locus_tag="ACGXWR_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032490535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFK0804434.1"
                     /translation="YILSFCTPKLNYLLAYIRLYSGVLHLRDSVRVSEKEKIKVTEMY
                     TSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRKKIENPHPLLQTTVEPS
                     KPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQMEVISALLQEKYHVEI
                     ELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYL
                     NQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLTPIVLEQA
                     FRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQLKNNEVIIIGEIPARC
                     IQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSRIDKVRYMFNKIT"
     gene            1266..1454
                     /locus_tag="ACGXWR_002987"
     CDS             1266..1454
                     /locus_tag="ACGXWR_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HFK0804435.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(1512..1865)
                     /locus_tag="ACGXWR_002988"
     CDS             complement(1512..1865)
                     /locus_tag="ACGXWR_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0804436.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            2396..2818
                     /locus_tag="ACGXWR_002989"
     CDS             2396..2818
                     /locus_tag="ACGXWR_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFK0804437.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            2815..3045
                     /locus_tag="ACGXWR_002990"
     CDS             2815..3045
                     /locus_tag="ACGXWR_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFK0804438.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            3543..3743
                     /locus_tag="ACGXWR_002991"
     CDS             3543..3743
                     /locus_tag="ACGXWR_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HFK0804439.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            3770..4963
                     /locus_tag="ACGXWR_002992"
     CDS             3770..4963
                     /locus_tag="ACGXWR_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFK0804440.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(5031..6596)
                     /gene="guaA"
                     /locus_tag="ACGXWR_002993"
     CDS             complement(5031..6596)
                     /gene="guaA"
                     /locus_tag="ACGXWR_002993"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFK0804441.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(6655..7578)
                     /gene="coaA"
                     /locus_tag="ACGXWR_002994"
     CDS             complement(6655..7578)
                     /gene="coaA"
                     /locus_tag="ACGXWR_002994"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HFK0804442.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            7774..8379
                     /locus_tag="ACGXWR_002995"
     CDS             7774..8379
                     /locus_tag="ACGXWR_002995"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFK0804443.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            8687..9703
                     /locus_tag="ACGXWR_002996"
     CDS             8687..9703
                     /locus_tag="ACGXWR_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFK0804444.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            9844..11145
                     /locus_tag="ACGXWR_002997"
     CDS             9844..11145
                     /locus_tag="ACGXWR_002997"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HFK0804445.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            11191..11853
                     /gene="deoC"
                     /locus_tag="ACGXWR_002998"
     CDS             11191..11853
                     /gene="deoC"
                     /locus_tag="ACGXWR_002998"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HFK0804446.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            11874..12272
                     /locus_tag="ACGXWR_002999"
     CDS             11874..12272
                     /locus_tag="ACGXWR_002999"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HFK0804447.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            12338..13420
                     /locus_tag="ACGXWR_003000"
     CDS             12338..13420
                     /locus_tag="ACGXWR_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFK0804448.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            13632..15194
                     /locus_tag="ACGXWR_003001"
     CDS             13632..15194
                     /locus_tag="ACGXWR_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0804449.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            15187..16320
                     /locus_tag="ACGXWR_003002"
     CDS             15187..16320
                     /locus_tag="ACGXWR_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0804450.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            16320..17276
                     /locus_tag="ACGXWR_003003"
     CDS             16320..17276
                     /locus_tag="ACGXWR_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFK0804451.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            17375..18541
                     /gene="deoB"
                     /locus_tag="ACGXWR_003004"
     CDS             17375..18541
                     /gene="deoB"
                     /locus_tag="ACGXWR_003004"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HFK0804452.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            18565..19383
                     /locus_tag="ACGXWR_003005"
     CDS             18565..19383
                     /locus_tag="ACGXWR_003005"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFK0804453.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            19400..20107
                     /gene="deoD"
                     /locus_tag="ACGXWR_003006"
     CDS             19400..20107
                     /gene="deoD"
                     /locus_tag="ACGXWR_003006"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFK0804454.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
BASE COUNT         6497 a         3640 c         4352 g         5794 t
ORIGIN      
        1 gtacattttg tcattttgta ctccaaaact gaactactta cttgcatata tacgccttta
       61 tagtggagta ctacatttac gagattcggt tagagtatca gaaaaagaaa aaataaaagt
      121 tacagaaatg tatacttcaa taaatggtga attatgtaag attgatagag cttattctgg
      181 agaaattgtt attttgcaaa atgagttttt gaagttaaat agtgttcttg gagatacaaa
      241 actattgcca cagagaaaaa agattgaaaa tccgcaccct ctactacaaa caactgttga
      301 accgagtaaa cctgaacaga gagaaatgtt gcttgatgcc cttttggaaa tctcagatag
      361 tgatccgctt ctacgatatt acgtggattc tacgacacat gaaattatac tttctttctt
      421 agggaaagta caaatggaag tgattagtgc actgttgcaa gaaaagtatc atgtggagat
      481 agaactaaaa gagcctacag tcatttatat ggagagaccg ttaaaaaatg cagaatatac
      541 cattcacatc gaagtgccgc caaatccttt ctgggcttcc attggtttat ctgtatcacc
      601 gcttccgttg ggaagtggaa tgcagtatga gagctcggtt tctcttggat acttaaatca
      661 atcatttcaa aatgcagtta tggaagggat acgctatggt tgcgaacaag gattatatgg
      721 ttggaatgtg acggattgta aaatctgttt taagtacggt ttatactata gccctgttag
      781 tactccagca gattttcgga tgcttactcc tattgtactg gagcaagcct ttagaaaagc
      841 tggaacagaa ttgttagagc catatcttag ttttaaagtt tatgcaccac aggaatatct
      901 ttcacgggca tataacgatg ctcccaaata ttgtgcaaat atcgtaaata ctcaactgaa
      961 aaataatgag gtcattatta ttggagaaat tcctgctcga tgtattcaag attatcgcaa
     1021 tgatttaact ttttttacaa atgggcttag tgtttgttta gcagagctaa aaggatatca
     1081 ggttaccact ggcgaacctg tttgccagac ccgtcgtcta aatagtcgga tagataaagt
     1141 aagatatatg ttcaataaaa taacttagtg cgttttatgt tgttatataa atatggtttc
     1201 ttattaaata agatgaaata ttctttaata tagatttgaa ttaaagtgga aaggaggaga
     1261 ttgttattat aaactacaag tggatattgt gtcctatttg tggaaataaa acaagactac
     1321 gaatacgagt ggatactata cttaaaaatt tccctttata ctgccccaaa tgtaagaacg
     1381 aaactttaat taatgttcaa aaaatgaata taataacaat caaagagcca gacgccaaga
     1441 cgcagagccg ataatttgag aaatgaaact ctcatcttat cggctctttt tgtttatctg
     1501 aattttactg actagccttc aatatttctt gcttcattga taccttttgc tagtgcttcc
     1561 attaaggata gttctttgtc tgtaaagcta tccatgtatt tttctacctg taaccttcga
     1621 gtgcttttaa tcaaattatc tgtaggtaag aaaaattcat caatagatac atggagtaat
     1681 gatacaagat catacagcac ttgtgtactt gggtgttgtc ctttgttttc tatatttgtt
     1741 aaataacgtg ggtcaatttc aatcattgtt cccacttgtt cacgagtgag accccgtttc
     1801 attcgagcct ctttaatcgc taaaccaacg gctctaaaat cgtatttatc ttctttttta
     1861 cgcatactaa atcacctcta tacattttac tgttcctata taaccataaa caggtataga
     1921 aaaacatgtt atatagttta tgagttccta tagaacactg tggaatttat taatgcgatg
     1981 aatccaattt caaatagaaa ggtcgctgat tttatttacc tatacaactt tataaaattt
     2041 agtcatactc ctagaaagta gataaaattg gcgacttaat ggagggaaaa gtcgccatga
     2101 gaaagataat ctgtcatcta gttctcttaa ttaagttctt atcaaaaaaa cttatccacc
     2161 tgtactggat agatatgacc atcaatgtgg ttttgcagat tacatagata gaaaaatcaa
     2221 agcatatgaa cagagaaaac aatctgttta tgtgcttttt tggtcactta ataaatatct
     2281 tttaggattt ctcttcattt atgcaacaaa tcccccgttc gtgtcggggt ttagtatgaa
     2341 gggagataaa gaagcacatg ccactccctt tcacgacaga aagggggtga aaagcatgaa
     2401 accatcttct tttcaagaaa ccatagaaaa tcagtttgac tatatctgca aacaagttat
     2461 tgaagatgaa cgaaaagatt acttcaaaca tctagacaga ctatcagcaa aagaagtctc
     2521 gttttctgat atagataact accttgtcaa ctctttttct actgttgata cgtacgtcac
     2581 tgatttccaa ctatttaaat tatttggatt aagaatcaat gttgaaagtg atttattaag
     2641 tgaagccctg cgtcatcttt cagagaaaaa acggaacatt attttacttc attactttat
     2701 ggatatgagt gatgtggaga ttgcggagtt actaaatttg aatcgttcga ctgtttatcg
     2761 tcatcgaata agtggactag ccatgattaa agaattcatg aaggagtgta aagaatgaaa
     2821 acagcttatc caagggttcc cttccccctc attgtaaagg cgacagatgg cgacgtggaa
     2881 gcaattaatc agattgttaa acattatcga gggtatacct caaaacgttc attacgtcgc
     2941 atgacagacg aatatggaaa ttctcatatg gttattgatg aaaccctacg tggcagaatg
     3001 gaaacgaaac tcatctctaa gattttatcg ttcgaaatta aatagtccca ttttttcgtg
     3061 gaagcgtgtc gaatcgtatc cacgcttccc gatttgggag gtttgttatt ccatcaaagc
     3121 atattgtgtg ttcagtaggt tttgataggc taacaagcca aacgttcttt gacaaccaaa
     3181 taaaggcaat cgaatacgtt tcggtaagaa aagagctgat gaactaacac gccatgacct
     3241 acaaaattag tgagcgattc atgttagtaa ttcgaaagta atctttagca ggattgctgc
     3301 catgactttc ttatcgtgat aatgatactc ccgtatagcc atagtccgag cgttagaagc
     3361 gtcacaggca atgggtacgg ctacatgaga accatgcaga agtgaaattc ctgtgagctt
     3421 tgctagagct gttcgattgc taagatattc ttctcttgtc agtgtattat tataaaacta
     3481 tttgatataa ttataggtga atattggagt tttcctagcc tataattggg aaaggagtaa
     3541 taatgataac ggtcacaaaa aaggatttag ttgagctagg atatggaact tctttttcag
     3601 cagacatcat aaaaaaagca aaagaattga tgattacaaa agggcatatc tactatcaat
     3661 ctcgaaagct agatagagtc cctcgtgaag ctgttgaaga aattctagga attcggtttt
     3721 caaatgaaaa caggtctgag tagtttttgc acagtaagga gtaaaaacta tggttaaaga
     3781 cccaataaaa aaagcaaaga atggaaccta ttattttcgt gcaaatctag gttatgattc
     3841 taaagggaaa aaaattcaaa aatatcgtag tggattcact actaaaaaag aagcaagaga
     3901 agaatattcg aaactgctat tgatgaaacc agaagaatta agtgagaata aggataaaat
     3961 gacgtttaaa cattatatct ttgaaatttt ccttccatgg tataagacac aggtaaagct
     4021 cagaacatat gaaaatcgct taccaactat taagaagcat ttctcttatt ttgataaaat
     4081 ggctgtttcc gatattgagc ctattgatgt gcaaaattgg caactaaaat tatcaaagaa
     4141 gtgtaagtct tcttatgtaa gagctgttca aggactattt tcagttgcta tggatcgagc
     4201 aattgtcctt gggataacca ccacaaatcc atctaagatt attggcaatg tgaaaaagca
     4261 aaagtctaaa attgaatttt ggacaaaaga agaatttgaa aaagtaatct ctctaattta
     4321 caaagaagat tactatcaac actttttatt tatctctctg tggtttttat ttatgactgg
     4381 aatgcgaatt ggtgaagcta ctgccattca atgggaagat attgattttg actcaggagt
     4441 actaaccatc aacaaaacac tctattacaa gaatcaatcg aattatagat ttgttgaacc
     4501 aaaaacaaag gcgagcgttc gtcatattgt attagataaa tgcacattaa cttatttatc
     4561 cgaatggaag gaagtacaac aaaatctaat tcagacagac tttgtaatga gctataacgg
     4621 tattcctacc caaaaacata cactatcata tgctattgaa cgctatgcta agctggctgg
     4681 tatccatcga atcagaatcc atgggttacg gcattctcat gcttccttgt taatcagtat
     4741 gggagaaaat ccacttatca ttaaagatcg tctaggacac gaagatattg agacgacttt
     4801 aggaacgtat ggacatcttt atcctaacag taatttcgag gtagctaaca aattaaatgg
     4861 agccatttcc tttaaagaag caaaacaaaa ttatgatact tcaccaaaga atcaatttac
     4921 tgtagactac ttgcgaaaca aagaaatgaa aaaagtgcaa taaaagtgca gtaaaaagat
     4981 aagaagagcc agaaaccctt ggtataagag gatttctagc tctcctacaa ctattcccac
     5041 tccactgttg ctggtggttt agaagtgatg tcatacacga tacggttgac gtgggctact
     5101 tcgtttacga tacgtacaga gattttttgc aagacttccc atgggatacg ggcaaagtca
     5161 gcggtcattc cgtcgattga agttacagca cggataccga ctgtgtagtc gtaagtacgt
     5221 ccgtcaccca taacaccgac agagcggatc cctggaagaa cagtgaaata ttgccagata
     5281 tcacggtcaa gtccagcagc tgcgatttct tcacgcaaga tagcatcaga ttcgcgtacg
     5341 atttctagct tgtcttcagt gatttcgcca agaacacgaa taccaagacc aggaccaggg
     5401 aatggctgac gccaaacgat tgaatcaggc atgcctaact gagtccctaa ttcacggact
     5461 tcgtctttga ataatgtgtt taatggttcg atcaattcaa attgcatatc ttctggcagt
     5521 ccacctacat tatggtgaga tttgatcgtc tgtgctgttt ctgtaccaga ttcgataacg
     5581 tcagtataca acgttccttg tgctaggaaa gagacgcctt cttcaccagc aagttttgtt
     5641 gcttcgtcat caaaaacata tacgaattca ttcccaatga ttttacgttt ttgttctggg
     5701 tcagatacac ctttcaactt gtctaagaag cgatctcttg catcgacttt gatgatgttc
     5761 aagccgaatt ttccgcctag actttccatt acttgttccg cttcgccttt gcgtagcaga
     5821 ccgtggtcaa caaagataga tgtcaattgg tcaccgatcg ctttttgtaa aagaacccca
     5881 acgacactag aatcaacgcc acctgaaaga ccaagcaaga cttttttgtc accaacttgt
     5941 tcacggattt tttctacttg catatcgata aagttatcca ttgtccagtt accttcacag
     6001 tgacaaacat caaaggcaaa gtggcgcagc aattcgattc cgtattcgga atgacgtact
     6061 tctgcatgga attggatacc ataaaaatta cgtgttgtgt cttggataga agcaatcgga
     6121 caatctttgc ttgttccgac tgtttcaaag ccttcaggaa ctttagttac caagtcacca
     6181 tggctcatcc atactgtttg ttgttttggt gtttctttaa acaagacagc ttgatcgctt
     6241 gttacttcta acaaggcttt cccatattcg cggtttttag caggctctac ggaaccgcca
     6301 agtttgtacg tgatcaattg cataccatag caaatcccta atacaggaat acctaaattg
     6361 aagatctcag gatcgatccc aaatgcattc tcatcatata cactgtttgg tccgccagaa
     6421 agaatgattc cctttggatt catcgctttt acttcttctg cagtaatgcg gtggctcaat
     6481 aattcggaaa agactccaag atcacgaata cgtcttgtga tcaattggtt atactgacta
     6541 ccgtagtcta atacgataat cttttcaacg ttcgtcatat cggcaacgtt tgtcaaattt
     6601 attaccccta tccctttaaa ttttatctca aaatagtcaa actattttaa aatgctaata
     6661 ttttcgcatg aaaatcgaat cgatgatatg attttcagtt ttatggagaa ttatatcggc
     6721 tcttcctcgt gtaggcaaga tatattcctg taaatttttc aaattcacat ttttccatac
     6781 atcttttgcc attttaaagg cttcttcacg atctccgata gcaaaacgat aataataatt
     6841 ctctggattt tggaaagccg tatccagtaa cgcaccaaaa cgatccaaat accatttttc
     6901 gatcagcacg ggatcggcat cgacatagac agaaaaatca aaaaagtcgc tgacgtagat
     6961 ttgctgattc gcaggtaatt gaagcgtatt gatcccctca acgatcaaga tatcaggctg
     7021 ctggatcaat tcgtacttgt ctggaatgat atcatacaca tcatgtgagt aaacaggtac
     7081 ttttatctct tcctgaccag attttacacg gttcaagaaa tcgatcagca tctccatatc
     7141 ataactttca ggaaatcctt tacggtccat gattccacgc tcttttaata tacgatttgg
     7201 ataaagaaat ccgtcagtcg tgatcagctg aacgtttctt cgtttgaagg tacgagacaa
     7261 aatcgtctgc agcagtctgg ctgttgtact ttttccaacg gctacacttc cggcgatccc
     7321 gataataaaa ggcggtactt ctacgtattt atgaagaaat aaacctttac tcaagaacaa
     7381 agattcaaat tctttcatat aaagataaat cagatgagca agaggtacat agatatctcg
     7441 aacatcctgc atggaaatgc ggtcattcaa acttttgata ttatctagtt catcttgtgt
     7501 caaaggtgct tgcccattac gataaaattc tcgccattct tctcttgcca cacggtagta
     7561 gttcattgga tcattcatat tagcctcctg cgttctccca tcaatggaac tattttaaca
     7621 caaaataaac gcaaacccca ccacttaaga gagattgccg atctttttgt ataatcttta
     7681 taatagaaag aaacggagtc ttattcttga cttgcgcacg gatacataaa aggatagact
     7741 gttgtcatga aagaaatgag aaggatggaa gacatgacaa atcattacta ttctgaacgc
     7801 ccagatacgg cgcacgattt tgaacaatgg gcttttgagt taaaaggcag aacctttcaa
     7861 tttgtaacag attctggtgt attttcacgt gaaacagtgg attatggttc acgtgtcctg
     7921 attgatgctt tcgattggga agagttacct gatgaaggaa agatcttaga tgtgggatgc
     7981 gggtatggac cgattgggtt agctttggca tttgcgacac agcggtttgt tgaaatggtc
     8041 gacattaatg aacgagcggt aagtctagcg caaggaaacg caaagcgtaa ccaaatcgaa
     8101 catgttgata tccatcaatc gaatatctat gaagcagttc atgaagaaac ctatgcagct
     8161 atcgtaagca atccgccgat ccgtgctgga aaaaaagttg tacatgaaat tttgacaggc
     8221 gcatatcctc ggttgaagaa gggcggtaca ctgacaattg tgatccagaa gaaacaagga
     8281 gcgccgagtg cgcaaaagaa aatggaagaa acatttggta atgcagaaat cgtcacaaaa
     8341 gataaaggat attatatcat caaaagtgtg aaagaataac tagctgaaaa atagtggagc
     8401 gacgaaagag tggaactggg cgtgcatgta cgggtacgta tcagttcttt ttttgttgag
     8461 aagtttttaa aaacaaagaa ctattttttc ttcaaaaaga aatagtagga acagagtcgt
     8521 tgttttttac gataaaataa ataagataca gaacttgtat agaaggctgc caagtcggta
     8581 gataaaggag gtttttatca aaaaacatac tttccttttt tctctattct tttcttgggg
     8641 gttttggtac actgataggg aatttagata gaagggagcc aataggatga agctgaccat
     8701 cagagatatc gcagaaatgg caggcgtatc agtaacaact gtctcacaga ttttgaataa
     8761 caaaggaagc agatttagtg ataagacaag aaaaaaagtg ttgtcgatcg tgaatgaaca
     8821 tcattataag cccgattatt tcgcttcaaa tgtgatcaat cgacattcaa agaccatcgg
     8881 aatgatcgtc cctgatgtca ctgatttctt cttctccaaa ctgatcgaag gtgtagagag
     8941 ctatttgaat cctttgggct atgtgatcat gttatgcaat tctcgtcata gccaagaaaa
     9001 tgagatcaag tatttacaag agctttccca ccgctcagtg gacggaatct tgctggccac
     9061 accaaatatt ttacctgaga aatatgcatt agacagcggt ttttatcaaa aaatgccaat
     9121 cattttaatc gatcgcggat tgaatcgtcg ggataacgga cggcttatcg taaaggaata
     9181 tgagggcgcc tatcaagctg tttcgctgtt tattgaaaat ggccatacga agatcggcat
     9241 gctgaaggaa accactggat actatcaatt agaagaacgt ttcaacggat atcgtcatgc
     9301 gctgaaagat catggcctgc cttttaatgg gaaatttgtt gaacatggag agttgactgt
     9361 ccaaggtgga tatactgcat caaaaaaatt actcaaacat aaagatatca cggctatttt
     9421 ttgcgggaat gatgccatgg cgatcggatg ctatcaggcg atcgatgaat tgggcaaaaa
     9481 aatcccagaa gatatctcag tcataggatt cgatggatta aagctgtcag aatacatgat
     9541 tccgcaattg acgacagtgc agcagccaag ttttgatatt ggattttatg ctgcacgttt
     9601 cctgatcgat acgatcgaat ttcctcaaag aaaagttccg aacaaagtgt tcgaaacaaa
     9661 attaattatt cgtgagagcg taaaagtatt gacaaagggc taactcggcg gtatattgct
     9721 tatgtaagca tttacaaagg ctagttagtg ctttttttat ttttagtaaa ccagtttact
     9781 aaagtggttt acctttccta aaaataatgt ataataccga atgaagacaa ggaggatcag
     9841 gcaatgcgaa tggtggatct gattgaaaaa aagagggatg gaaacgagct gtcgaaagag
     9901 gaaatcgagt acatcgtcac gaactatacg aatggaaaga ttccagatta tcaagtcagt
     9961 gcattattga tggcaatttt ttatcaagac atgacaaatg aagaaatcac gaacttaaca
    10021 ttggcgattg ctaattctgg tgatgtcatc gatttgagtt ctcttgaagg aataaaggta
    10081 gataagcatt cgacaggtgg cgttggtgac acgaccacat tgattttagc ccccctagta
    10141 gctagtgtcg gagtgacagt ggctaaaatg tctggacgcg gtctaggtta cacaggtggt
    10201 acactagaca agctagaagc aattcccgga tttcagatcg agctttcgga tgaagaattt
    10261 gtacgcattg ttaatgaaag taaagtagcg gtaattggtc aatcaggaaa cttggcaccg
    10321 gcggacaaaa aattgtatgc cttgcgtgac gtcacagcga ccgttgattc tcttccgctg
    10381 attgccagtt cgattatgag taaaaaaatc gcggcaggag cagatgcaat cgttttggat
    10441 gtgaccactg gagacggtgc tttcatgaag aacatcgaag atgcaagacg tctggcaaag
    10501 accatgacga gcattgggaa actggctaac cgagaaacag tggcggttat ctcagatatg
    10561 tcagaacctc ttggcgaagc tatcggaaat agtctagaag ttgtcgaggc aatcgaaaca
    10621 ttacaaggaa atggtccaga agatctagta gaaatgtgct acgccttagg aagccaaatg
    10681 gttgttcttg ctggcaaagc taagacaacc gatgaagcaa gaacgttgct tcaagaagct
    10741 ctggaatcag gtaaagcgtt agcaaaattc aaagaaatga tccaaaatca agggggagac
    10801 ccagcgatcg tggaacatcc agaacgaatt ttgactgcac gctacacaat ggagcttcct
    10861 gctaaacaaa gcggagttgt gtcaaaaatc gtggcaaatg aattaggaat tgctgcaatg
    10921 atgctaggtg ctgggcgtaa aaccaaagaa gaagatattg atcacgctgt tggattgaaa
    10981 ctgcataaaa aaattggtga cactgtgaca aaaggtgagt cactattgac gatctatagt
    11041 aacgacgaag aaatcacttc tgtcattgaa ttattatata aaaatattga aattggtgaa
    11101 tcggcaatga agccaacgtt gattcatgac atcatcacag aataaaggaa aaaagcggac
    11161 tttaccgttt taaagaaaag gggaaaagaa atggaactaa accgaatgat cgaccatact
    11221 attttgaaag cagacgcatc taaagaagct gtgatgcaaa ttatcgaaga agcaaaaaaa
    11281 taccattttt attctgtctg catcaatcca gcatgggttg cgctagcgaa agaacaatta
    11341 caaggtgagc cagtagccgt atgtacagta atcgggtttc ctctaggagc aaacacaccc
    11401 gagacaaaag catttgaaac aacagatgcc atcaataacg gtgcagatga agtcgatatg
    11461 gtcatcaata tcggtgcttt gaaatcaaag gatgatcaac aagtccaaaa agatatcgaa
    11521 gcagttgttg aagcagcaaa agatcgtgcg cttgtcaaag ttattattga aacatcgtta
    11581 ttagatagag aagaaatcat ccgagcttgc gaaatagcaa aagctgcagg cgctgatttt
    11641 gtcaaaacat caactggttt ctcaacaggc ggagcaaagg tagaggatgt ccgtttgatg
    11701 cgtgaaactg taggaccaga aatgggtgtc aaagcttccg gcggtatcca taacgaagaa
    11761 gaagcaatgg caatgatcga agctggtgct acaagaatcg gaacaagcgc aggagtagca
    11821 atcgtatctg gttcaactgg tgaaggctat taattttttc aaaggagaag ctcatggcag
    11881 aactcaaaca agaatggatc aacacagcta ttgaagcgtt agataaagcc tatgttcctt
    11941 attcccattt tccggtaggc gcttgtctcg taacggaatc aggcaagatt tatcaaggca
    12001 tcaacattga gaatgcatca tttggattaa cgaattgtgc cgagcgcaca gcttttttca
    12061 aagcagtatc tgaaggagaa aaaacattta cgcatctagt cgtagcgggg cacacccccg
    12121 atcctatctc tccttgtggt gcatgtcgac aagtaatggc agaattctgt tcccctgata
    12181 tgccggttac gctagtagga gacaatggtg tgacgaaggc aacgaccgtt cgtgcactgc
    12241 tgccttatgc atttactgaa aaagatctat aactcatgtt cattcagtca gctgactgtt
    12301 gaaaaataaa acaattattt taggaggctt tacagaaatg aaaaaagcaa aattatttgg
    12361 tttaggtgct gtcgcactag cagcagggtt atttttaggt gcatgcggca acaacggctc
    12421 tactgattca tccggtggca aaagctcatc agacacaaca actgcagcat tgatcacaga
    12481 cacaggtggt gtagacgacc gttcattcaa ccagtcagct tgggaaggac tagaaaaatg
    12541 ggggaaagat caaggacttt cacgaggaaa tgatggcttc caatatttcc aatcttcaaa
    12601 tgaatcagat tacatcccaa atattgacca agcattgaat gctggattca aaacgatttt
    12661 tggtattggt tataaactaa aaccagcgat ccaagaacaa gcaacaaaca atacaggtac
    12721 gaactttgtt attatcgatg atgtcatcga tggattagat aacgttgtat ctgcaacttt
    12781 caaagacaac gaagcttctt atcttgcagg tgttgcagca gcttatacga ctgaaacaaa
    12841 cgtagtcggc tttatcggcg gtgtaaaagg tgaagtaatc gatcgttttg atgctggatt
    12901 caaagccggt gttgatgcag gtgcgaaaga attaggaaaa gaaatcaaag tattgaatca
    12961 atatgctggt gacttctctg ctccagataa aggacgttca attgctcaag gtatgtatgc
    13021 acaaaacgca gatatcatct tccatgcttc aggcggtaca ggtaacggtg tattccaaga
    13081 agcaaaatca ttgaacgaat caggcgacaa aaaagtttgg gttatcggtg ttgaccgcga
    13141 ccaatcagac gaaggcgaat acacattaaa cggcgaaaag aaaaacttca cattgacatc
    13201 tacactgaaa gcagttggaa cagtagtaga agatttggca caaaaatcag cggacggtaa
    13261 attccctggc ggcgaacaca ctgtttatgg attgaaagaa gacggtgttg gtctaacaga
    13321 aggacaactt tctgacgaag cgaaaaaagc agttgatgaa gcaaaagaaa aaatcatttc
    13381 aggtgacgta aaagttccag aaactcctga agaaaactaa aaccatttct atagccttgt
    13441 tagacacatg tttgacaagg ctatggtttg attagaacaa gaattgttca tttatccaag
    13501 ctgccttgtg acagtttgga taagggaaca actccctgaa gtaatgtttg tttcaaaaga
    13561 agaacgctca ctaagcgtga atcttagtca atcgttgccc tagatagaaa tcgttaggat
    13621 gtgaaaaaaa ggtggttcaa gaaaatattg tcatagaaat gcagaatatt accaaagaat
    13681 ttggaacatt caaggcaaat gacaacatca atttacaagt aaaggcagga gaaattcatg
    13741 cgttgcttgg agaaaacggt gctggcaaat ctacattgat gaacgtgctt tccggattat
    13801 tagagccgac atcagggaaa attttgatgc gtgggaaaga agtaaagatc acaagtccga
    13861 ccaaagccaa ccaattaggg attgggatgg tccatcagca ctttatgctt gttgatgcct
    13921 ttactgtaac agaaaacatc gtgttgggaa gcgagcctag tcgcgcaggg atgcttgacc
    13981 ataaaaaagc acgaaaagag atccaaaaag tttctgaaca gtatggattg tcagtcaacc
    14041 cagatgctta cgttcgtgat atttcagttg gaatggaaca acgggtagaa attttaaaaa
    14101 cactttaccg aggagcagat gtactgattt ttgatgagcc gacagctgta ttgacccctc
    14161 aagaaattga tgaattaatc gtgatcatga aggaattagt caaagaaggc aagtcgatca
    14221 ttttgattac gcataagtta gatgaaatca aagcagtagc tgaccgctgt acagttatcc
    14281 gccgtggaaa aggaatcggt acagtcaacg ttaaagacgt aacctcacaa caattagccg
    14341 atatgatggt tggaagaacg gtttcattca aaacgatgaa aaaagaagcg aagcctcaag
    14401 aagtcgtttt gtctattgaa aatctagtgg tgaaagaaaa tcgtggatta gaagccgtga
    14461 aaaacttgaa cttagaggtt cgtgctggcg aagtacttgg tatcgctgga atcgatggaa
    14521 acgggcagtc ggagttgatc caagctttga ctggtttgcg aaaggcagaa agcggacata
    14581 tcaagctaaa aggggaagac atcactaata aaaaaccccg aaaaatcact gaacatggtg
    14641 taggacacgt gccagaagac cgtcataaat acgggttagt cctagatatg acattatctg
    14701 aaaatatcgc actacaaacc tatcatcaaa aaccttacag taaaaacggc atgctgaatt
    14761 attcagtaat gaatgaacat gccagagaat tgatcgaaga atatgatgtt cgaacaacga
    14821 atgaacttgt tcccgcaaaa gctttatcag gcggaaatca gcaaaaagca attatcgctc
    14881 gtgaagtcga ccgagatcct gatctgttga ttgttgcaaa tccaactcgt ggactggatg
    14941 taggtgcgat cgaatttatt cataaacgtc tgatcgaaca aagggacaaa tacaaagcag
    15001 tgttactgat cagtttcgaa ttagaagaaa ttttaaatgt ttcggatcgt attgctgtta
    15061 tccatgaagg agaaattgtc ggtatcgttg atccgaaaga aacatctgaa aatgaattag
    15121 gtctattgat ggcgggctat accttagaag aagcacgaaa agagttagaa aagggggctg
    15181 gcgcacatga atgatcgcag cgaaaaattc cgtaatttat tagtgcctgt actttcagtt
    15241 gttttaggat tgatcttagg cgcgatattg atggctgctt ttggttttca gcccatccaa
    15301 ggttattctt ctatgctaga tgcagccctt ggttcgcaaa gagggatagg tgaaacgtta
    15361 aggcaagcaa cgccgttgat ttttacagca ttaggttttt ctgtagctaa ctcagctggg
    15421 tttttcaata ttgggctttc tggacaagca ctttgcgggt ggatcgtcag tgtctgggtg
    15481 gcacttgcgt ttccagatct gccaaaagtt gttttgcttc cgttatgcgt gatcttaggt
    15541 gccttagctg gtgcgatggc agcggctgtt ccaggtttac ttcgagcatt ttttggaaca
    15601 agtgaagtga tcgtaacaat catgatgaac tatatcttat tatacgtaag cacatttgct
    15661 ttacatgaag tgatgcctga aagctatcgc tcaagtttgg actcttccaa tatgatcagt
    15721 caaaatgcct cactgcggtt accatggtta acacaagctt ttggcggctc tcgcgtaaac
    15781 tcaggattat ttttagcaat catcgcgctt attttcgttt ggctgctgat gaagaaaacg
    15841 actttaggat ttgaaatccg ttctgttgga ttgaatcctt ttgcttctga gtatgcagga
    15901 atgagtagta aacgtacgat cgttttgtcg atggtcattt ctggcgcttt ggcagggctt
    15961 ggcggtgtgg ttgaaggatt aggaacgtat caaaacttct ttgttcaaac gacttcgcta
    16021 tctattggat ttgacggaat ggctgtttcc ttgcttggtt ctggatcagc aatcggtatt
    16081 cttttatcag cgatcttgtt cagtattttg aagatcggtg gacttggcat gcagacagga
    16141 gcaggtgttc cgtttgagat cgtcaatgta tcgattgctt tgattatctt ctttgtcggg
    16201 atcaacttcc tgattcgttt cgtcatggct aaagtcttcc aagggaaaaa acaagaagag
    16261 atcgttgcga caatagaatc gaaaccaacg aatcaaaacc atgaaggggg cgaactataa
    16321 tgtcgactat cgaattaatt gccttgatcc ttacttctac actggtttat tcaacaccgc
    16381 taattctaac gtcactaggc ggaacttttt ctgaacgaag cgggatcgta aacgtagggc
    16441 tagagggaat catggtcatg ggtgctttta gttccatcgt tttcaacttg acgatgagtc
    16501 catcacttgg ttctatgaca ccatggatcg ctattttagt gggtggcgtc gtaggtatcc
    16561 tattttctct gattcacgca gtagcaacag tcagtttgcg tgctgaccat attatcagcg
    16621 ggacagtaat taatctgatg gcacctgctt taggtgtttt cttgatcaaa gcatggtatg
    16681 gtaaaggtca aactgataac atcacgcaga atctggggta tttttctttc ccaggattag
    16741 cagatattcc ggtcattgga ccaattttct ttaaaaatac attcttacct gcttattgtg
    16801 ctattttgat tgctgtccta gcttgggtga tcatcttcaa gacgaaattc ggcttgcgcc
    16861 tccgttcagt tggtgaaaat cctcaagctg ccgacacatt aggtatcaat gtatatgcta
    16921 tgcgttattc aggcgtactg atttctggct tgttaggcgg tatgggcggt gctgtttttg
    16981 ctcagtcgat ttccggtaac ttttcagctg gtacgatcgt tggacaaggg ttcatctcca
    17041 tggctgctat gatctttggt aagtggaatc ctttaggggc aatgggtgcc tcattgttct
    17101 ttggttttgc tcaaagcttg agtatcattg gcgcacaatt accagttatt tcttcgattc
    17161 cgccagtatt gctgcaaatt gctccatatt tgctgacaat cattgtgctg gttgttttct
    17221 tagggaaagc ttctggtcca aaagcaaacg ggaagaacta tatcaaatca aaataatctt
    17281 ttagcgaata aaaagggtgg gttacgggaa gtgtttttcg tctcgccctt tttgttttaa
    17341 aggcaataaa aataaaaaga aagaaggaat aatcatgttt aaacgcgtac atctgatcgt
    17401 catggattca gtaggaattg gagaagcacc agatgccgat aagttcggtg atgttggttc
    17461 tgatacatta ggacacattg cgaaagaagc aggattgaac gttccacatt tagagcagct
    17521 tggtttagga acgatccgtc ctcttgaagg tgtggaatca gtgaaagatc atcaaggcta
    17581 tgcgacgaaa ttagaagaag tttctgtagg gaaagatacg atgacaggcc actgggaaat
    17641 catgggattg aatatcaaaa ctccatttcg tgtgtttcct aatggattcc ctgatgatct
    17701 gatcaaacaa atcgaagaat tttctggccg taaagtcgta tgtaacaaac cttatagcgg
    17761 aacagctgtt attgacgatt acggtgaaca ccaaatgaaa acaggcgatt taattgtata
    17821 tacttctgcc gatcctgtcc ttcagatcgc ggcacatgaa gaaatcattc ctttagaaga
    17881 attatatcgg atttgccaat tcgttcgtga tataacaaaa gatgatccgt atatgattgg
    17941 ccgaatcatt gcacgtccgt acgtgggtga accaggagac ttcacacgaa caagcaatcg
    18001 ccatgattat gcgttgaatc cattcggaca cacagtcctt gattctttga aagaagcagg
    18061 aaaggacgtg attgctgttg gaaagatcaa cgatattttc aacggacaag gaatcactga
    18121 atctgtccgc acgaaaagca atatggatgg cgttgaccag ctgctgaaag ttatgaaaaa
    18181 cgatttttca ggaatcagct ttaccaattt agtagatttt gatgcattat acggtcatcg
    18241 tcgggatgta gtcggctatg cgcatgcgat tgaagaattt gacttacgaa ttccagaatt
    18301 gcttgaagcg atggaagaag acgacttgct aatgattaca gccgatcacg gaaacgatcc
    18361 gacgtttact ggtaccgatc atacgcgaga atatgtaccg ttattggttt acagtaaaaa
    18421 aatgaaagaa caaggggcat tgcctcaagg atattattca gatatttcag caacgattgc
    18481 tgagaacttt agtgtttctt cgactgaaaa tggcgaaagc ttcttgaaat tattaaaata
    18541 atctttttaa ataggagaaa gcaaatgacc aagttaagcg agatgttaca agaaacgacc
    18601 cagtttatcc ttgataaagg agtaaaagaa attgattttg gtttgattct aggttcagga
    18661 ttaggtgaat tagcagatga aatcgaagat gctgtaatga tttcttatga tgagatcccg
    18721 ttctttcctg tttcgacagt agttgggcat gcaggaaagc tagtttatgg gtctctggca
    18781 ggcaagaaag tgttagccat gcaagggaga ttccactact atgaaggtca ttccatgcaa
    18841 acagtgacct atccagtacg tgtgatggcc ggactagggg cccattcagt cattgtgact
    18901 aatgcatgtg gtggtgtcaa cgaatcattt gtaccaggag atttgatgct gattaccgat
    18961 catatcaatt ttactggtga aaatcctttg atcggtccga atgaagatgc aatgggccct
    19021 agatttccag atatgagtca agcttatacg cctgactatc aagcaacagc aaaagcagca
    19081 gcagaaaaac taggtttgga tcttaaagaa ggcgtatata tgggctattc tggaccaact
    19141 tatgaaacgc ctgcggagat ccgaatgtct cggacaatag gagccgatgc agtagggatg
    19201 tcgactgttc cagaagtcat cgtagcagct cacagcggat taaaagtgtt aggaatctct
    19261 tgtattacca acttagcagc aggtatgcaa gcgaatctga gccatgaaga agttgtagaa
    19321 acaactcaga gagtcaaaca atcttttaaa gcattggtta aagaaacatt gacattattg
    19381 taataggagg aacaataaaa tgagtgtgca tattgaagcg aaagaaggcg agatcgccga
    19441 taagatttta cttccgggag atcctttgcg agctaaatat attgcggaga cttttttgga
    19501 agatccagtt tgttacaatc aggtacgcgg tatgttaggc tttaccggca aatataaagg
    19561 agaacgtatt tctgttcaag gaacaggaat gggaatgcca tcagccacca tctatgccca
    19621 tgaattgatc cagtcgtatg gtgtaaagaa attgattcga gtaggtacat gcggtgcatt
    19681 gtcaaaagac gtccatgttc gtgatttagt actagcacaa ggtgcagcga ccagttcttc
    19741 gatgatcgaa aaaaatttcc aagcctttca ttttcctcca atcagtgatt tcaatctatt
    19801 actgaaagca tatgagatag ctaaagaaaa gggctatacg gttcatgtag gaaatgttct
    19861 ttcggaagat tctttctaca aagatgattt gacagagacg ttccaattag ctgaacttgg
    19921 cgttttagga gtggaaatgg aagcagcggc tctttattac ttaggcgcga aataccatgt
    19981 gcagacatta agtttgatga ccgttagcga ccatttgatc accggtgaag aaacaacagc
    20041 tgcagaacgt caatctacgt tcaatgaaat gatcgaagta ggattggaaa cagcgatagc
    20101 agaataagaa ggaaatgaaa aagctgccct gcattaagta ataagaacat ccaagcaaaa
    20161 atagctcctc atgtttttga cttggctgga cttattattg caaatgtaag cttttgaaca
    20221 ccgtttacca agaggttgtg aatctgccgt ttaactctga gtcacaagga acaatttcaa
    20281 aaa
//
LOCUS       DAYNVV010000198        16759 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.guided.057, whole genome shotgun sequence.
ACCESSION   DAYNVV010000198 DAYNVV010000000
VERSION     DAYNVV010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16759
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.guided.057"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(134..577)
                     /locus_tag="ACGXWR_003007"
     CDS             complement(134..577)
                     /locus_tag="ACGXWR_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HFK0804455.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="ACGXWR_003008"
     CDS             complement(795..2135)
                     /locus_tag="ACGXWR_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFK0804456.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="ACGXWR_003009"
     CDS             2404..3300
                     /locus_tag="ACGXWR_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFK0804457.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFNMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTSFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="ACGXWR_003010"
     CDS             complement(3450..4391)
                     /locus_tag="ACGXWR_003010"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFK0804458.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="ACGXWR_003011"
     CDS             4517..5638
                     /locus_tag="ACGXWR_003011"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFK0804459.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /gene="eat(A)"
                     /locus_tag="ACGXWR_003012"
     CDS             5896..7398
                     /gene="eat(A)"
                     /locus_tag="ACGXWR_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFK0804460.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7465..7992
                     /locus_tag="ACGXWR_003013"
     CDS             7465..7992
                     /locus_tag="ACGXWR_003013"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFK0804461.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLAEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            8203..9264
                     /locus_tag="ACGXWR_003014"
     CDS             8203..9264
                     /locus_tag="ACGXWR_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFK0804462.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9267..10163
                     /gene="murQ"
                     /locus_tag="ACGXWR_003015"
     CDS             9267..10163
                     /gene="murQ"
                     /locus_tag="ACGXWR_003015"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFK0804463.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            10177..12159
                     /locus_tag="ACGXWR_003016"
     CDS             10177..12159
                     /locus_tag="ACGXWR_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFK0804464.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="ACGXWR_003017"
     CDS             complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="ACGXWR_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFK0804465.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            12881..14305
                     /locus_tag="ACGXWR_003018"
     CDS             12881..14305
                     /locus_tag="ACGXWR_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFK0804466.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(14486..15259)
                     /locus_tag="ACGXWR_003019"
     CDS             complement(14486..15259)
                     /locus_tag="ACGXWR_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFK0804467.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(15256..16161)
                     /locus_tag="ACGXWR_003020"
     CDS             complement(15256..16161)
                     /locus_tag="ACGXWR_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFK0804468.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(16315..16635)
                     /locus_tag="ACGXWR_003021"
     CDS             complement(16315..16635)
                     /locus_tag="ACGXWR_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HFK0804469.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
BASE COUNT         5395 a         3060 c         3454 g         4850 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggtgttccag
       61 aagtagcttc ttcttatttc ttgaagctga tcacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg gatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgt caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gttccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaataacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat ggctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgattagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccgccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa gcgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttaat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacatc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgtat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tggctgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     8101 aaatgaaatt taattgtttt aataaaagta ttgaaatttt gtttctttag atatatactc
     8161 tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata
     8221 tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat
     8281 ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa
     8341 aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat
     8401 atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa
     8461 gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac
     8521 tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat
     8581 gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca
     8641 cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt
     8701 caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat
     8761 caaggattgc caactttgga agaacatcga gggatccatc ctcttgcagg cgctctagat
     8821 ctattagcaa gtaacacgga tattgtttac atcggagatg caggtctgtc agaaaacgtt
     8881 caggagcaat ttgcttcttt ccaaaaagaa cagacagtct tgctccatac ggaacctgta
     8941 gatgaagaat tttacgaata tatattaggg aagcatacga atcggcaaga cgatgcaaga
     9001 gatgtcatac gaagcgtaga tgcacgtttt cgagagattc cgcctatccc agcaagaaat
     9061 acagctacgc gtatgaaagg gtctattact ttagataacg aaaagtattt gcgctatatg
     9121 ggtgagatcc aattaaccaa atatgatttg ccagcggatg aaaaagtgaa tgtagtagct
     9181 aaagttatca aagaagagct accattgatc aaccaaatca aagctggtat gaactatcaa
     9241 tttataagaa aagaaggaag ataaaaatga gcaaaatcaa tttagagaac ctaacaacgg
     9301 aacgcagaaa ccaagaaact tttggattag atgagatgag tatttctcaa gccgttcaac
     9361 taatgaacaa agaagatcag aaagtggccg ctgcggttga aaaagaactg acaagtatcg
     9421 aaccagtgat tgctaacacg attgagtcct ttaaaaaagg tggacgtctg atttatatgg
     9481 gagccggaac aagtggaaga ctaggtgtgt tagatgctgc tgaatgcgta ccgacattcg
     9541 gtgtagaacc ggaaatggtc ataggtctaa ttgctggtgg agaagaagca atgactgtag
     9601 ctgtcgaagg ggccgaagat tcttatgagc tagggcaaga agatctaatc aagctgaatt
     9661 tgacaaaaaa tgatatagtt attggtatcg cagctagcgg tcgtacacca tatgtgatcg
     9721 gtggattaga ttacgcaaaa tcgatcggtg ctgtcacagg aacgatttct tgcaataaac
     9781 aagccgaaat cagtaaacac gcggatttcc caatcgaagt cgatgcaggt ccagaatttt
     9841 tgacaggctc tactcgattg aagtcaggaa cagcacaaaa acttatcttg aatatgattt
     9901 ctactatcag tatgattggt ataggtaaag tattcaataa cttgatggtc gatgtcaaac
     9961 caacaaacga aaaactaatc gaacgctcaa aacgaatcat catgcaagcg acagaagctg
    10021 attacgaaac agctgaaaag tactttgaag aagcagatca aaatgttaag ctggctatcg
    10081 tcatgatttt gacaaatagt gataaagagg aagctcaagc aaaattagct gaagcaaacg
    10141 gatttgtaaa agggacctta tgagggggaa aagaccatgg caaaaaacga actgactttg
    10201 gaagaactgg caaaacaaat ttataaaggg gcaggcggca tgggcaatgt agaaagcatt
    10261 gtccactgca tgactcgtgt gcgtatgaag atcatcaatg atgatcttgt aaatgtctct
    10321 gaattaaaag cgattccagg agtgcttggt gtagtagaag atgaacagct tcaagtcatc
    10381 atcggacctg ggaaagtgaa caaagtagca cagcaaatgg ttgatttggc aggcgtgaaa
    10441 ttaggagaaa aactttcttc tgtaagtaca gctacagcaa attcatcagc atctggaaaa
    10501 gaccgtgtaa acgaacgggc acaagaaatg aaagcggcac aaaaatcgaa acaaaaacca
    10561 tctaaaatca aatcggtatt aaaagacatt tctaatatct ttgtgccaat gattcctgca
    10621 tttgtcggta ctgggatcgt ggcagggatt gccgcagttt tagcaaactt agtcacagcc
    10681 ggaacacttg atgcagcaac atggcaacaa tatatcgatg tgatgaacat cttgaaaaac
    10741 gggatgttta gctacctagt tatctataca ggtatcaatg ctgcacaagt ttttggtgca
    10801 acaccaactc ttggtggagt tatcggggcc gttgtgatgc tgacagggat gaatccggaa
    10861 gcaccactga aaaacttatt tactggtgaa gctcttgcag ctggacaagg tgggatccta
    10921 ggtgtcatct tcgctgtttg gctattgtca atcgttgaga aaaaactgca taaagtagta
    10981 cctgatgcgg tagatatcat cgttacacca actctttcat tgattgccat cggtctgatt
    11041 gaaattttct tcatcatgcc tttagcaggt ttcatttctg atggcatggt cggtgggatc
    11101 aactgggtac ttggcgttgg tggagcattt gccggcttcg ttctaggcac attattcttg
    11161 ccgatggtta tgttcggact gcatcaaatt ttgactccaa tccatgtgca aatgattgat
    11221 gaaactggtc gtacgctatt gcttccaatt cttgcgatgg ctggtgcagg acaagtgggt
    11281 gcagcattgg cattatggat tcgctgcaaa aaagataaag aattaacaga aatgatcaaa
    11341 ggagctttac cagtcgggat cctaggaatc ggcgaaccat tgatttacgg agtaacatta
    11401 cctctaggac gcccatttat tactgcttgt atcggtggag gtatcggcgg ggcagtgatc
    11461 ggaatgatcg gaaatgtcgg ggctatcgct attggacctt caggagccgc tttgatccca
    11521 ttgatctctg acggtaaatg gttaggctac atccttggat tattggcagc ttatgctggt
    11581 ggcttcgttg ctacattctt cttcggtatt cctaaagacc gtttagaaaa agaagaatta
    11641 gcgactgaaa cagccacagt aaatgaagtg cctgaaaaag tagtacctca aacttcagct
    11701 gaaagtgtga ctatcctctc atcagttgct gacggaacag ttgtttcttt agataaagca
    11761 agtgatccag tttttgcaca aaagatgatg ggtgaaggct actttgtaga accagaaaac
    11821 ggacatatct attctccagt tactggggta gtcagctctg tcttcccaac gaaacacgct
    11881 attgggatca caacgccaaa tggtttagaa atcttgcttc atatgggaat caacacagtt
    11941 gacttaggcg gtacgccatt tgatgtgaaa gtaacagaag ggcagcaagt gacacctgat
    12001 acgcttgtag cagaagctga cttagaagcg atcaaagcag caggcaaaga aacatccatg
    12061 atcgtcttgg taaccaatat ggatcgtgta aaaaactttg tcttggaaaa aacaggtaaa
    12121 gcaaaagcaa aagcacctgt gatggatgtc aaagcttaat atgatagaaa caatagaaac
    12181 gaaagaagaa actgaaatct atttttcagc ttcttctttt ttattattta ttgttttctg
    12241 ctaaaatctg ataaattcgt gtcacatcag atggtgttcc ccgtaattca taatctgcca
    12301 agaaaggaaa gccaaatgtt tgtgcatatt gtttggctgt tagacaatac tgattattga
    12361 agtttttatt tccgctaccg actacaccaa gacaaagttt atgattgtct tcatgttcca
    12421 gatattcacg catcgtttcg gtcaagattt ctgtatcacc gttatctaaa ccatttccgc
    12481 cgtctaaata agtaggaacg aaagtaaaaa atggttctgt ttctttcgta aaatcactat
    12541 tttcatggat ttcttttaaa gtaacttcag gattgacagg atcttctgca tgcatttttt
    12601 cagcatattc tgctagatgt ttggcaaagg cacgcgtatt tcctgaaatc gatatatata
    12661 aaatgttcat ggatcatcct ccaattcttt ccttttagta tagcatcttt tttaagtttt
    12721 ttggtggtgt aatttggaaa gggactaggc gctttgcttg tataatgaga aaaaagccgg
    12781 tagaattata tttctattaa agtttttatt aattaagtaa aaataaaaaa ggtttgttat
    12841 actttttgat aaaagcggtt ttattttgga ggatgcttac atggatacag agcaacagaa
    12901 aaaaggaatt ggtttaattc cacttgctgc cttagtaatt ggttcagcga ttggaggtgg
    12961 cgtatttggt attatgacgg acatctccgg atcggctggc ggcccagcta ttttcagttg
    13021 ggtactcgta ggaacagcaa tgttgatgct ctccttgtcg atcaataata tcaataaaaa
    13081 acgtccagat ttaaaaggcg ggatctttag ttacgcagaa gaaggttttg gccgtttcgc
    13141 tggttttatc agcggttggg gttactggct cacatgctgg ttaggcaacg tagcttttgc
    13201 aacattgttg atgagcgcat taggatattt cttcccagta tttgaaggtg ggcaaaatct
    13261 ggcatcgatc gtgatgagta cagtcttttt atggggatat gcatggctag tgaatcgggg
    13321 agtcgaaaat gctagtttcg tcaatgctat cgtcacattc tgtaaattag tgccattatt
    13381 tttatttatt gtagtagcta tcagcacgtt ttcgatccaa caattcattg ataacttttc
    13441 tagcgacatt atattgaatg cgaatggaca gccgatcccg ttttccagtc aagtattgag
    13501 ttgcatcatg gtgatgcttt gggtatttgt tggtattgaa ggagcctctg tcgtaggttc
    13561 acgagcaaaa aaacaatcag atgttgggaa agcaacgatt ctagggatat tcggcttgat
    13621 tattatttac gtcttggttt ccatgcttcc atatgggaca atgacgatga atcagctgca
    13681 aacgatcaag gcgcagcctg ctatgggcta tgtgtttgaa atgatggttg gtaaatgggg
    13741 agcagtcgtg atcaacggcg gtttgatcat ttctttagtt ggtgtttggc tctcatggac
    13801 gatcttaccg attgaaacaa tgggaaacat ggctgaagac ggacttttgc ctaaagcatg
    13861 gggaaaactc aacaaaaatg gggcaccaac ttatgctatc gtattgacga cgttatgtac
    13921 gaatgtcttt ttactttcat tattattcac tgacagtgct tataactttg cttacacact
    13981 tggtacagca gctattttct tcacgtggct tttcttagga ttgtaccaaa tgaaactttc
    14041 ttatcagcgg aaagaatggg tccaattttt agtagggctt ttagcaagtg cctttcaagt
    14101 atgggctatg ctagtcgtag cctttaatga agtaatgctt gttcttgttc ttttcttgcc
    14161 aggcatttat ttttacctca aagcacgtaa ggagcaaaac gagcctgtac aacatatcca
    14221 cttagataag attttactta taggtgtgac gatggtcgga gtgattgcaa tggttttatt
    14281 tgccactggg atgcttcacg tatagaagta taaaagaagt ataaagagag gttgtgagcc
    14341 tgtcgtttat tcaaaaacat actaggaaag gagctgtgac acaaatgttg tcacagctcc
    14401 tttttcagaa taaacggtgt ttaagagaca gccaatcggc aataaggctg aacgtctctt
    14461 tcacagcctc ttttttgatg agtcatcata cattttttcg cttaaatacg agatatccta
    14521 atgctaagaa caaaacgatg taagctaaat taccgaatag catttgatta gtagaaagat
    14581 gagtcaattg cttcatgatc tcttcgtttc caatttggtt ttgcagattc aacatactga
    14641 tcggattcca tttgatccac tcccattttt ggatgagtgc aataaggata ccagatatga
    14701 ttgacgaagc aaaataaaag acgattcctg ctgagatgga tgcaccggaa ctattgataa
    14761 agcaagcaat catcaacact aaacttaaaa tcagccataa accgatataa ctacccaaag
    14821 tataagtgaa caagctttgg atcagtgttt gaccagtaga aaccttctcc gtgaaggaaa
    14881 tcgaagggaa aagaatcagt ttcatcaaca cagtgacaat aatagctaaa aggtataaat
    14941 aaacagaata aataactaat gtgatccatt tgcttactaa tatttctcct cgagaatact
    15001 ttcgataaag gagatttttc aatgtaccat attgtgcttc catcgaaatg atcgtgcttg
    15061 cagctgcaat catgataaag acaatccaag atgtggcact aaaaagctga gcagtcattt
    15121 caactggatc aatgatcgtc gtgtattttt tggctagaag tgctgttcct atgagcaaaa
    15181 caactaatag aacagataaa acagcagttg actttttctt gatcaattta aataattctt
    15241 gttttacaag caatgtcatt tttcttcttc cccctttact gaatccagaa tttccaatag
    15301 agaagattcc aaatcattcg tcagatgctg gacgtctgtc acatggatat tttgtgcaga
    15361 caatagctgg atcacggttc ctaataattc ttcgttttct tttaaaagct tgattttatc
    15421 aggatcttcc aaagtatatc cagcttctgt caagatcgtt cgagcagcta gatcatttgt
    15481 tgtagagata acgatgaaat cttgcgctgt ttggttcaat tcagccattg tacattgttt
    15541 gatgatcttt ccttgattga tcaggatcag ctcatcgacc attttttcaa gctcgctgag
    15601 taagtgactg gagatcaaga aagaggtgcc ctgagtagcc aagtcggtaa tgatttttcg
    15661 cacatctctt gttgcttgtg gatccaaacc gttcatcggc tcatctaaaa taacgataga
    15721 cggatggttc agtaaggcaa gagcaattcc caatttttgt ttcattccca acgagtagga
    15781 tttcgctttt ttgtgaatgt acttttccat cttgagctga ttcacgatag tgtcgatagc
    15841 agatacatcg ttggtttcag agaataactt cagatgatca tagcctgtta agaatggata
    15901 gatacccggg tattcgatca atgctcctac ttgttccaac cctttatgac tagagggaga
    15961 aatctcattt tcaccaatac agattgttcc atctgagtaa tggatcagtc ctaaaatagc
    16021 tttcatgatc gttgtttttc cagcgccatt aggacctact aatccaacga ttttgccagg
    16081 ggataagcta aaactgacat cgctgagggc ttgtttgtga ccaaagttct tggataattc
    16141 ttggaccgaa agacttttca aaaatattca ctccttttct atagatagta caagcataca
    16201 cctgatgagt ggagaagtcg ctaggtcatt ggacttattt cttatttttt cataaaaaaa
    16261 ttgaatatta aataaaaagg cttatttttt ctgatcagta cttattccaa gtgtctagtg
    16321 gccgctagta atcttgatgc caatgatact gatgagtagc atccccacaa agaaccaagt
    16381 ggaaagattc agcttatcat gaaacaagac cacaccaatt atgaccgaac caactgcgcc
    16441 aatccctgtc cagataggat aagagagact catcggcaaa cttttgattg cctttgacaa
    16501 aaagtaaaaa ctagcaatca tgccaatcac tgtgtaaaaa gaataattga ttttagaaaa
    16561 accatcactc catttcatca tcgttgacca gaatacttcc aaaattcctg ctatgattaa
    16621 ttccatccat gccatactta cattcctcct taactataaa aaaatacaca aaaagaggaa
    16681 aatcatccct tcaaagacct aatggaatga tcatcctctt tatcctaccc ggtggcagat
    16741 tgtatatctt tttctgtag
//
LOCUS       DAYNVV010000199         7476 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.guided.100, whole genome shotgun sequence.
ACCESSION   DAYNVV010000199 DAYNVV010000000
VERSION     DAYNVV010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7476
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.guided.100"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            107..190
                     /locus_tag="ACGXWR_003022"
     CDS             107..190
                     /locus_tag="ACGXWR_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HFK0804470.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            315..1052
                     /gene="erm(B)"
                     /locus_tag="ACGXWR_003023"
     CDS             315..1052
                     /gene="erm(B)"
                     /locus_tag="ACGXWR_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFK0804471.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1222..1482
                     /locus_tag="ACGXWR_003024"
                     /pseudo
     CDS             1222..1482
                     /locus_tag="ACGXWR_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            1645..2310
                     /locus_tag="ACGXWR_003025"
                     /pseudo
     CDS             1645..2310
                     /locus_tag="ACGXWR_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2346..2591
                     /locus_tag="ACGXWR_003026"
     CDS             2346..2591
                     /locus_tag="ACGXWR_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFK0804472.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2694..3563
                     /locus_tag="ACGXWR_003027"
     CDS             2694..3563
                     /locus_tag="ACGXWR_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFK0804473.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3544..4278
                     /locus_tag="ACGXWR_003028"
     CDS             3544..4278
                     /locus_tag="ACGXWR_003028"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFK0804474.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4311..5219
                     /locus_tag="ACGXWR_003029"
     CDS             4311..5219
                     /locus_tag="ACGXWR_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFK0804475.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            5216..5758
                     /gene="sat4"
                     /locus_tag="ACGXWR_003030"
     CDS             5216..5758
                     /gene="sat4"
                     /locus_tag="ACGXWR_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HFK0804476.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5851..6645
                     /locus_tag="ACGXWR_003031"
                     /note="aph(3')-IIIa"
     CDS             5851..6645
                     /locus_tag="ACGXWR_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HFK0804477.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            6921..7463
                     /locus_tag="ACGXWR_003032"
     CDS             6921..7463
                     /locus_tag="ACGXWR_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFK0804478.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPVLLQSFK"
BASE COUNT         2622 a         1129 c         1566 g         2159 t
ORIGIN      
        1 atttgatagt agatttaaaa ctttgcaaca gaaccatttt gtgtataata ggaattgaag
       61 ttaaattaga tgctaaaaat ttgtaattaa gaaggaggga ttcgtcatgt tggtattcca
      121 aatgcgtaat gtagataaaa catctactgt tttgaaacag actaaaaaca gtgattacgc
      181 agataaataa atacgttaga ttaattccta ccagtgacta atcttatgac tttttaaaca
      241 gataactaaa attacaaaca aatcgtttaa cttctgtatt tatttacaga tgtaataact
      301 tcaggagtga ttacatgaac aaaaatataa aatattctca aaacttttta acgagtgaaa
      361 aagtactcaa ccaaataata aaacaattga atttaaaaga aaccgatacc gtttacgaaa
      421 ttggaacagg taaagggcat ttaacgacga aactggctaa aataagtaaa caggtaacgt
      481 ctattgaatt agacagtcat ctattcaact tatcgtcaga aaaattaaaa ctgaacattc
      541 gtgtcacttt aattcaccaa gatattctac agtttcaatt ccctaacaaa cagaggtata
      601 aaattgttgg gagtattcct taccatttaa gcacacaaat tattaaaaaa gtggtttttg
      661 aaagccatgc gtctgacatc tatctgattg ttgaagaagg attctacaag cgtaccttgg
      721 atattcaccg aacactaggg ttgctcttgc acactcaagt ctcgattcag caattgctta
      781 agctgccagc ggaatgcttt catcctaaac caaaagtaaa cagtgtctta ataaaactta
      841 cccgccatac cacagatgtt ccagataaat attggaagct atatacgtac tttgtttcaa
      901 aatgggtcaa tcgagaatat cgtcaactgt ttactaaaaa tcagtttcat caagcaatga
      961 aacacgccaa agtaaacaat ttaagtaccg ttacttatga gcaagtattg tctattttta
     1021 atagttatct attatttaac gggaggaaat aattctatga gtcgcttttt taaatttgga
     1081 aagttacacg ttactaaagg gaatggagat aaattattag atatactact gacagcttcc
     1141 aagaagctaa agaggtccct agcgcctacg gggaatttgt atcgataagg ggtacaaatt
     1201 cccactaagc gctcgggacc ccttgtagga aaatgtccta agtgtggcaa caatattgta
     1261 ttaaaaaaat cgttttatgg ttgttcaaat tatcctgaat gtaagtttac tttagctgaa
     1321 cattttagaa agaaaaaact aaccaaaacg aatgtaaaag aattactgga gggaaaagaa
     1381 accctggtaa aaggaatcaa aaacaaagag aaaaagccct acaatgccgt tgtaaaaatt
     1441 ggggaaaagg gatatattga ttttatctct ttttcaaaat aaacatgggg ctgacccaaa
     1501 agtagctcct atatgaaaaa tagaggtctt tccatttaga tagtagtgga aagacctcta
     1561 tttatctttt gaaagtgaat acaaaaataa agcacactct gctataatat aggtgattaa
     1621 tccatttgag agaggtgctt tatcatgtat caaaattata ccataaacca actttgtttg
     1681 cctatagatc ttgaaattaa attagaagaa aatgattttg ctcatgccat tgtgcagttt
     1741 gttgactcta ttcccgatga agtctttctt ccttattatc aatctatggg tagaccccaa
     1801 tatcatcctc gtatgctact ttccattatt ctttgtgcct atattcaagg ggtttattcg
     1861 ggccgccaaa tacaaaatat gctgatagat agtattcgga tgcgctactt atctcaagag
     1921 caattcccta actttcgtac tattaatcgt tttcgcgttc atccgattat gaacgatatt
     1981 ctagatcatt catttgttca atttcgtgag ctactggttc aaagtggctt aatcagtggc
     2041 agtgctctat acattgatgg tacaaaaatt gaagcggatg cgaataaata ctctttcgtt
     2101 tggaaaaaaa gtattttaaa gtataaggat agccttgatc aaaaagccct tgaaaactac
     2161 caacaaatgg tggaaacaaa aatcttacct gagttaatag atgatttaaa ggatgaactt
     2221 tctatagaag agattgaaag gattcgtcaa tctttggaag aaaaggaaaa tcaattaatt
     2281 gaagcgattg accaaaccga aacagtagaa gggggctgac ccattattaa taaggagtgg
     2341 acaacatgat tgatgtaaat gagctattgg aagaagctat tagagaaact gaaaatctaa
     2401 atgatggcga agtttttctt gttaaagatt tattcaaggg atatgtgggg aataggatac
     2461 ccagaaagga tcgacttctg cttggaacgt tatttttaaa ccatgttagc aaaatgaatg
     2521 gtaatttaaa ggctattgaa aagacttcat ctaatcagca gaggtataaa aagacaattg
     2581 ataagtttta actatctttt gtgaaattaa aaaaattata aatatgttga gtagaagcaa
     2641 aagatttggc ttggaatttt tacagcagtg aatcgataaa aggagcatgc ttgatggtag
     2701 ataatattat taaatcagta gcagagaaat tatcctctct gtcttatata gaaggtattg
     2761 ttttaggtgg ttcacgtgca aggggcaccc atacagagga ttcggatata gatatcggca
     2821 tctattacaa ttcagaatca tttgacataa atactattaa tcaattcgct acaaagctgg
     2881 atgatgagca tagaaataac cttgttgtac ctcccggagc atggggtgat tggattaatg
     2941 gcggcggatg gttagtcata aacgggtatc atgtggattt aattttacgt gatattaaac
     3001 gtgtggaaca aataatgaaa gatacagagc acggaattgt tactgccaat tatcagactg
     3061 ggcatcccca tggttatatt agtgcaatgt atcgaggaga attagcgatt agcaaaatac
     3121 tatatgctaa gaatgaaagc ttatgcgaat taaaaaaaca ggcagaaact tatcccaatg
     3181 ctttgcagaa aagtttagtt aactttttta tgtttgaagc agggttctct ttaatgtttg
     3241 taaaagcaaa ttcgggaaca gacgataaat attatattgc gggtcatgtt tttcgtatag
     3301 tttcatgttt aaatcaagtg ttatttgcat gtaataatgc ttattgtatc aacgaaaaga
     3361 aagctataaa actgcttgaa acttttgaac ataaacctga aaaatatacc gagaaggtaa
     3421 atcatatttt tgaagtactc ggtatctcac tttttgaatg ctacgacatg accgagaagc
     3481 tttataatga agtgaatgaa attgtatcgg agataaataa ctttttaaac gaggagagtt
     3541 cagatgaaag aaaacaaata tgatgataat atattttttc aaaaatacag tcaaatgagt
     3601 cgctcgcaga aaggactggc tggtgcggga gaatgggaga ctttgaaaaa gatgctacct
     3661 gattttaagg gtaagcgtgt gcttgattta ggatgcggct atggatggca ctgtatatat
     3721 gcgatggaaa acggtgcttc ctctgtagta ggtgttgata tttctcataa aatgctcgaa
     3781 gtagcaaaag gaaaaaccca ttttccacag attgaatatg aatgctgtgc catagaagat
     3841 gtggatttcc cagaggagag ctttgatgta atactaagtt cgcttgcgtt tcattatgta
     3901 gcagactatg agaatttaat aaaaaagata tataggatgc tgaaggctgg tggcaattta
     3961 gtttttacag ttgaacatcc tgtttttact gctcatggaa cacaagactg gtattataac
     4021 gaaaaaggag aaatactgca tttcccggtg gacaattatt attatgaggg caaacggaca
     4081 gctatgtttt tggaagaaaa ggttacaaaa tatcatagaa cactgaccac atatctaaat
     4141 acactgcttt caaatagttt tataataaat cagattgtgg agccacagcc gccagagaac
     4201 atgatggata ttccggggat ggcggatgaa atgcgacgcc caatgatgct gattgtatcg
     4261 gcaaaaaaga agatgtaata atatagaaaa aataaacgag gagtatgtaa atgagatcag
     4321 aaaaagaaat gatggattta gtactttctt tagcagaaca ggatgaacgt attcgaattg
     4381 tgacccttga ggggtcacgc gcaaatatta atatacctaa agatgaattt caggattatg
     4441 atattacata ttttgtaagt gatatagaac cgtttatatc taatgatgac tggcttaatc
     4501 aatttgggaa tataataatg atgcaaaagc cggaggatat ggaattattc ccacctgaag
     4561 aaaagggatt ttcctatctt atgctatttg atgattacaa taaaattgat cttaccttat
     4621 tgcccttgga agagttagat aattacctaa agggcgataa attaataaag gttctaattg
     4681 ataaagattg tagaattaaa agggacatag ttccgactga tatagattat catgtaagaa
     4741 agccaagcgc aagggagtat gatgattgct gcaatgaatt ttggaatgta acaccttatg
     4801 ttattaaagg attgtgccgt aaggaaattt tatttgctat tgatcatttt aatcagattg
     4861 ttcgccatga gctgctgaga atgatatcat ggaaggtcgg catcgaaaca ggctttaaat
     4921 taagtgtagg caagaactat aagtttattg aaaggtatat atccgaggat ttgtgggaga
     4981 aacttttgtc cacctaccgg atggattcct atgaaaacat atgggaagca ttatttctat
     5041 gccatcaatt gttcagggcg gtatccggtg aggtggcgga aaggcttcat tatgcctatc
     5101 cggagtatga taggaatata acaaaatata ccagggacat gtataaaaaa tacactggta
     5161 aaaccggctg cctggatagc acatatgccg ctgatataga agagaggcgg gaacagtgat
     5221 tacagaaatg aaagcagggc acctgaaaga tatcgataaa cccagcgaac catttgaggt
     5281 gataggtaag attataccga ggtatgaaaa cgagaattgg acctttacag aattactcta
     5341 tgaagcgcca tatttaaaaa gctaccaaga cgaagaggat gaagaggatg aggaggcaga
     5401 ttgccttgaa tatattgaca atactgataa gataatatat ctttactacc aagacgataa
     5461 atgcgtcgga aaagttaaac tgcgaaaaaa ttggaaccgg tacgcttata tagaagatat
     5521 cgccgtatgt aaggatttca gggggcaagg cataggcagc gcgcttatca atatatctat
     5581 agaatgggca aagcataaaa acttgcatgg actaatgctt gaaacccagg acaataacct
     5641 tatagcttgt aaattctatc ataattgtgg tttcaaaatc ggctccgtcg atactatgtt
     5701 atacgccaac tttgaaaaca actttgaaaa agctgttttc tggtatttaa ggttttagaa
     5761 tgcaaggaac agtgaattgg agttcgtctt gttataatta gcttcttggg gtatctttaa
     5821 atactgtaga aaagaggaag gaaataataa atggctaaaa tgagaatatc accggaattg
     5881 aaaaaactga tcgaaaaata ccgctgcgta aaagatacgg aaggaatgtc tcctgctaag
     5941 gtatataagc tggtgggaga aaatgaaaac ctatatttaa aaatgacgga cagccggtat
     6001 aaagggacca cctatgatgt ggaacgggaa aaggacatga tgctatggct ggaaggaaag
     6061 ctgcctgttc caaaggtcct gcactttgaa cggcatgatg gctggagcaa tctgctcatg
     6121 agtgaggccg atggcgtcct ttgctcggaa gagtatgaag atgaacaaag ccctgaaaag
     6181 attatcgagc tgtatgcgga gtgcatcagg ctctttcact ccatcgacat atcggattgt
     6241 ccctatacga atagcttaga cagccgatta gccgaattgg attacttact gaataacgat
     6301 ctggccgatg tggattgcga aaactgggaa gaagacactc catttaaaga tccgcgcgag
     6361 ctgtatgatt ttttaaagac ggaaaagccc gaagaggaac ttgtcttttc ccacggcgac
     6421 ctgggagaca gcaacatctt tgtgaaagat ggcaaagtaa gtggctttat tgatcttggg
     6481 agaagcggca gggcggacaa gtggtatgac attgccttct gcgtccggtc gatcagggag
     6541 gatatcgggg aagaacagta tgtcgagcta ttttttgact tactggggat caagcctgat
     6601 tgggagaaaa taaaatatta tattttactg gatgaattgt tttagtacct agatttagat
     6661 gtctaaaaag ctttaactac aagcttttta gacatctaat cttttctgaa gtacatccgc
     6721 aactgtccat actctgatgt tttatatctt ttctaaaagt tcgctagata gagttctata
     6781 ttagagatgt aaagagtttt ggtgaagagg tttgtgagta tggcttttat aaccagggtg
     6841 caatgagaag cactaacagc agctagctta agaacgcata ggatatactt tttatggaag
     6901 tcacagagga ggaataaaat ttgaacagga ttaacagagt aacctctatt cttattcagc
     6961 tgcaatcaaa aaaaataatt cctgccaaag aaattgcaca gcgatttaat ataagcttaa
     7021 ggacagttta cagagatatc cggacacttg aagaagccgg aataccaatt ggatctgagg
     7081 ccggaaaagg atattttctt gtagagggct tcctacttcc gccggtaatg tttacagcgg
     7141 cggaagtggg tgcattgatt acagcaggga aatttttaaa ttgccatgga gatgaatcat
     7201 ttataaagga ttttgattca gctatgtata aaatcaaatc tattttgaag catggtgaaa
     7261 aaaactatgc acaggagttg gagaacagta ttaacgtgta cagcacatct ggacagaaaa
     7321 atacattggc ggataacgtt attgcagcaa ttcagactgc aatctgcaat aaaagggtaa
     7381 tatcaattca atatcctgca tcaggagggc aagaaccgga aagcagaatg atagagccgg
     7441 ttctgttgca aagttttaaa taaagaataa aatccc
//
LOCUS       DAYNVV010000200         4584 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.guided.117, whole genome shotgun sequence.
ACCESSION   DAYNVV010000200 DAYNVV010000000
VERSION     DAYNVV010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.guided.117"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            83..994
                     /gene="vanY"
                     /locus_tag="ACGXWR_003033"
     CDS             83..994
                     /gene="vanY"
                     /locus_tag="ACGXWR_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HFK0804479.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1147..1632
                     /gene="vanZ-A"
                     /locus_tag="ACGXWR_003034"
     CDS             1147..1632
                     /gene="vanZ-A"
                     /locus_tag="ACGXWR_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFK0804480.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(1919..2248)
                     /locus_tag="ACGXWR_003035"
     CDS             complement(1919..2248)
                     /locus_tag="ACGXWR_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HFK0804481.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            2553..2882
                     /locus_tag="ACGXWR_003036"
     CDS             2553..2882
                     /locus_tag="ACGXWR_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFK0804482.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            2872..3159
                     /locus_tag="ACGXWR_003037"
     CDS             2872..3159
                     /locus_tag="ACGXWR_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFK0804483.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPNLLCGTHENFYEQLKKIR"
     gene            complement(3438..4001)
                     /locus_tag="ACGXWR_003038"
     CDS             complement(3438..4001)
                     /locus_tag="ACGXWR_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFK0804484.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
BASE COUNT         1618 a          683 c          767 g         1516 t
ORIGIN      
        1 tagaatgatt ttctatcagt cctagaaatt atagagccaa tatttcatac ttccaactat
       61 atagttaagg aggagactga aaatgaagaa gttgtttttt ttattgttat tgttattctt
      121 aatatactta ggttatgact acgttaatga agcactgttt tctcaggaaa aagtcgaatt
      181 tcaaaattat gatcaaaatc ccaaagaaca tttagaaaat agtgggactt ctgaaaatac
      241 ccaagagaaa acaattacag aagaacaggt ttatcaagga aatctgctat taatcaatag
      301 taaatatcct gttcgccaag aaagtgtgaa gtcagatatc gtgaatttat ctaaacatga
      361 cgaattaata aatggatacg ggttgcttga tagtaatatt tatatgtcaa aagaaatagc
      421 acaaaaattt tcagagatgg tcaatgatgc tgtaaagggt ggcgttagtc attttattat
      481 taatagtggc tatcgagact ttgatgagca aagtgtgctt taccaagaaa tgggggctga
      541 gtatgcctta ccagcaggtt atagtgagca taattcaggt ttatcactag atgtaggatc
      601 aagcttgacg aaaatggaac gagcccctga aggaaagtgg atagaagaaa atgcttggaa
      661 atacgggttc attttacgtt atccagagga caaaacagag ttaacaggaa ttcaatatga
      721 actatggcat attcgctatg ttggtttacc acatagtgcg attatgaaag aaaagaattt
      781 cgttctcgag gaatatatgg attacctaaa agaagaaaaa accatttctg ttagtgtaaa
      841 tggggaaaaa tatgagatct tttattatcc tgttactaaa aataccacca ttcatgtgcc
      901 gactaatctt cgttatgaga tatcaggaaa caatatagac ggtgtaattg tgacagtgtt
      961 tcccggatca acacatacta attcaaggag gtaaggatgg cggaatgaaa ccaacgaaat
     1021 taatgaacag cattattgta ctagcacttt tggggtaacg ttagcttttt aatttaaaac
     1081 ccacgttaac taggacattg ctatactaat gatacaactt aaacaaaaga attagaggaa
     1141 attatattgg gaaaaatatt atctagagga ttgctagctt tatatttagt gacactaatc
     1201 tggttagtgt tattcaaatt acaatacaat attttatcag tatttaatta tcatcaaaga
     1261 agtcttaact tgactccatt tactgctact gggaatttca gagagatgat agataatgtt
     1321 ataatcttta ttccatttgg cttgcttttg aatgtcaatt ttaaagaaat cggattttta
     1381 cctaagtttg cttttgtact ggttttaagt cttacttttg aaataattca atttatcttc
     1441 gctattggag cgacagacat aacagatgta attacaaata ctgttggagg ctttcttgga
     1501 ctgaaattat atggtttaag caataagcat atgaatcaaa aaaaattaga cagagttatt
     1561 atttttgtag gtatactttt gctcgtatta ttgctcgttt accgtaccca tttaagaata
     1621 aattacgtgt aagatgtcta aatcaagcaa tctgatcttt catacacata aagatattga
     1681 atgaattgga ttagatggaa aacgggatgt ggggaaactc gcccgtaggt gtgaagtgag
     1741 gggaaaaccg gtgataaagt aaaaagctta cctaacacta tagtaacaaa gaaagcccaa
     1801 ttatcaattt tagtgctgag gaattggtct ctttaataaa tttccttaac gttgtaaatc
     1861 cgcattttcc tgacggtacc cccaaactaa gatttcatag atagattttc tgataacttt
     1921 aaaaaacacg aatagcggaa aggatgtctt cattcgctaa agagtaataa actacttttc
     1981 catcttgacg tgattttgcc attccatgtt tttttaaaaa acgtaaatgg tgtgacgttg
     2041 tagcgacact agcagtaagt atttctgcta aatcacagac gcacatttcc ttataggttt
     2101 ctaaagcata gaaaatttta attctagaaa aatcgctgaa acatttccct aacacaagta
     2161 agtttgaaaa atctttttga tccaatttat tttttattcc atttactttt tctttatgta
     2221 cgacagtcac ttggcaaact tttttcattc atctcacctc acattcaaac gattatttga
     2281 atgaagtata cctatttgat cactcttttg tcaatctacc ttaattccaa tacactatta
     2341 taagcaattt catgtattga agtaaactta cttgcaagtg cgtttttgat tccaagttaa
     2401 aaacatatta ttattctaca taatttccta atcaaataaa actcctttga aaattgttct
     2461 aaaggagttt tattattttg tatttctact aaaaatagcg tacaatgtaa ttactaagta
     2521 attacgaaat gtaaaataat ggaggaaata atatgattac aaaaacaaga aaacaaggaa
     2581 attctattat gttaacggtc cctaaagaat tcgatgtgcc caatggtgtt gaagtagaag
     2641 ctaagcttgt agagaatggt atcctttatg agtttgtaga gcctaaaaaa gaattttttg
     2701 attttagtga agatattttg gctgatattc tttcagaagg ttatagcaaa caagagatct
     2761 taaaagaatt tagaaataga aaaaatgcgt taacttctgc atttaaatct attgctgaag
     2821 atactgttgc aaattctaaa ccgatgacaa aagaggagtt ggcagcagaa attggcttat
     2881 gagattctac cttctaaaca cgtaataaag tatctaaaaa aattaaaaga gaaaacatta
     2941 aaagaacaat ttttaacgat aatttatgat gagatagcag ttcgtcctca ttcgggagaa
     3001 caaaaaacgg gtgatttatc aggaatttgg gctattggat tcaagtatgc aggtacgaca
     3061 tatcgcgttg catatgaaat taaagataat gcagtgatac ctaacttact atgtggaacg
     3121 catgaaaatt tttatgaaca attaaaaaag attaggtaag aacccaatgt ttcaacttga
     3181 gaggatagac gacactttaa aagataattt ttaacagctg agagttgtaa taccctataa
     3241 ttttaaacca ctaacctata tatttatgaa aaatagaaaa aattaaaacg cattttaagc
     3301 ctctttcaaa ttaaaagctt catccttatg cacaaagagg gcttaaaatg cgttatttta
     3361 tattgttttt tagtaataat aaaaaaatca ctctaattct cccataaata ttatagattc
     3421 ctaaagatta aaatagatta ttccctattg tcttttaagt agcggtagag tgttgccttg
     3481 ctaataccag tcatttccgt aatttctttt acgctataaa cctgactttt atacaatttt
     3541 actgctcgat caacatcttt ctggttcact cgtggacggc cacctttacg acctctcgca
     3601 cgtgcacttt tcaaaccttc tttggtacgt tcaacaatta aatcacgttc gaactgacta
     3661 aatgcttgga agacagtcat cattaagcgt ccgtgaggcg tgctggtatc gaagttttct
     3721 ttcaagctca ccagcttaac atggtgttct tcaaaatagg taacaaggtc aatcaaatcc
     3781 tttgtactac gacccaatcg agaaaaactt tctacaatta ccgtatctcc cggacgaatt
     3841 ttatctttta aacgatttag ttggggacga accgctttgg ttcccgtcat tttctcagtt
     3901 aggatttcat tacaattttg ttcattgagt aagtctaatt gacgatttag ttcttgtgaa
     3961 cgtgtactca ctcgggcata accataaatg tatccactca tgcttttctt cctttcgtac
     4021 tttaattctg gcttgattgt atcataaaag ggagttatag atacatagtt aatgcaacaa
     4081 gttatgatac aaaatatgac ctcttttatt taataaaaga ggtcatttca ttttgtctca
     4141 taatcgattg tttttgatac gagtgtgtat acgaaataaa caaaaaaatc ttaagtaaat
     4201 ttctagatac ctaatttaat cctaactagt gtatcctaaa gttaataacg agtttatcac
     4261 aatgaaaatt ataaaatgct cccatattag atataacatg caatatttga attagaacta
     4321 caaaatttat tcgttttata aagtaaataa tgttgagata ctaaggaata gaatattata
     4381 aggaattgag ctgaatgtat tggataaaaa aagaataact ttattagaga tggactataa
     4441 aaatgctcgt aattttcttc tgaagtctga aagctatttg aatgctcagc taccagaata
     4501 tattagtttt gacgaaactt taaaatctgc taaaaaagtt ttaacttcgc cgtttgtata
     4561 attaagcgag acaaataaaa aagc
//
LOCUS       DAYNVV010000201         3970 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.guided.129, whole genome shotgun sequence.
ACCESSION   DAYNVV010000201 DAYNVV010000000
VERSION     DAYNVV010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3970
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.guided.129"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="ACGXWR_003039"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="ACGXWR_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HFK0804485.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2039..3412
                     /gene="tet(L)"
                     /locus_tag="ACGXWR_003040"
     CDS             2039..3412
                     /gene="tet(L)"
                     /locus_tag="ACGXWR_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008493 - tetracycline transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015904 - tetracycline transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HFK0804486.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIKKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
BASE COUNT         1256 a          613 c          816 g         1285 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcaggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata
      241 gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt
      361 catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta
      481 atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa
      541 caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa
      601 tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa ttgctccttg
      661 taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct tatagaagtg
      721 ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg cggaaatgtc
      781 ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct ttatggcgga
      841 atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc cggggaaatt
      961 gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta
     1261 aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac
     1321 atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg
     1381 ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt
     1441 caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat
     1501 gtgacggatt gtaaaatctg ttttaagtat ggcttatact atagccctgt tagtacccca
     1561 gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata tctttcacga
     1681 gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt gaaaaataat
     1741 gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg tagtgattta
     1801 actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta ccatgttact
     1861 accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa agtacgatat
     1921 atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt ttcttgttaa
     1981 ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg aattaattat
     2041 gaagtgtaat gaatgtaaca gggttaaata caaccaaatt ttaatttggc tttgcgtttt
     2101 atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg atattgcaaa
     2161 tgattttaat aaaccacctg cgagtacaaa ctgggtgaac acagccttta tgttaacctt
     2221 ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca aaaggttact
     2281 cctatttgga attataataa attgtttcgg gtcggtaatt gggtttgttg gccattcttt
     2341 cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg catttccagc
     2401 actcgtaatg gttgtagttg cgcgctatat tccaaaggaa aataggggta aagcatttgg
     2461 tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg gtggaatgat
     2521 agcccattat attcattggt cctatcttct actcattcct atgataacaa ttatcactgt
     2581 tccgtttctt atgaaattat taaagaaaga agtaaggata aaaggtcatt ttgatatcaa
     2641 aggaattata ctaatgtctg taggcattgt attttttatg ttgtttacaa catcatatag
     2701 catttctttt cttatcgtta gcgtgctgtc attcctgata tttgtaaaac atatcaagaa
     2761 agtaacagat ccttttgttg atcccggatt agggaaaaat atacctttta tgattggagt
     2821 tctttgtggg ggaattatat ttggaacagt agcagggttt gtctctatgg ttccttatat
     2881 gatgaaagat gttcaccagc taagtactgc cgaaatcgga agtgtaatta ttttccctgg
     2941 aacaatgagt gtcattattt tcggctacat tggtgggata cttgttgata gaagaggtcc
     3001 tttatacgtg ttaaacatcg gagttacatt tctttctgtt agctttttaa ctgcttcctt
     3061 tcttttagaa acaacatcat ggttcatgac aattataatc gtatttgttt taggtgggct
     3121 ttcgttcacc aaaacagtta tatcaacaat tgtttcaagt agcttgaaac agcaggaagc
     3181 tggtgctgga atgagtttgc ttaactttac cagcttttta tcagagggaa caggtattgc
     3241 aattgtaggt ggtttattat ccataccctt acttgatcaa aggttgttac ctatggaagt
     3301 tgatcagtca acttatctgt atagtaattt gttattactt ttttcaggaa tcattgtcat
     3361 tagttggctg gttaccttga atgtatataa acattctcaa agggatttct aaatcgttaa
     3421 gggatcaact ttgggagaga gttcaaaatt gatccttttt ttataacagg aattcaaatc
     3481 tttttgttcc attaaagggc gcgattgctg aataaaagat acgagagacc tctcttgtat
     3541 cttttttatt ttgagtggtt ttgtccgtta cactagaaaa ccgaaagaca ataaaaattt
     3601 tattcttgct gagtctggct ttcggtaagc tagacaaaac ggacaaaata aaaattggca
     3661 agggtttaaa ggtggagatt ttttgagtga tcttctcaaa aaatactacc tgtcccttgc
     3721 tgatttttaa acgagcacga gagcaaaacc cccctttgct gaggtggcag agggcaggtt
     3781 tttttgtttc ttttttctcg taaaaaaaag aaaggtctta aaggttttat ggttttggtc
     3841 ggcactgccg acagcctcgc agagcacaca ctttatgaat ataaagtata atgtgttata
     3901 ctttacttgg aagtggttgc cggaaagagc gaaaatgcct cacatttgtg ccacctaaaa
     3961 aggagcgatt
//
LOCUS       DAYNVV010000202         3970 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.guided.130, whole genome shotgun sequence.
ACCESSION   DAYNVV010000202 DAYNVV010000000
VERSION     DAYNVV010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3970
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.guided.130"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="ACGXWR_003041"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="ACGXWR_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HFK0804487.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2039..3412
                     /gene="tet(L)"
                     /locus_tag="ACGXWR_003042"
     CDS             2039..3412
                     /gene="tet(L)"
                     /locus_tag="ACGXWR_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008493 - tetracycline transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015904 - tetracycline transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HFK0804488.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIKKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
BASE COUNT         1255 a          613 c          817 g         1285 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcgggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata
      241 gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt
      361 catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta
      481 atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa
      541 caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa
      601 tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa ttgctccttg
      661 taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct tatagaagtg
      721 ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg cggaaatgtc
      781 ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct ttatggcgga
      841 atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc cggggaaatt
      961 gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta
     1261 aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac
     1321 atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg
     1381 ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt
     1441 caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat
     1501 gtgacggatt gtaaaatctg ttttaagtat ggcttatact atagccctgt tagtacccca
     1561 gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata tctttcacga
     1681 gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt gaaaaataat
     1741 gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg tagtgattta
     1801 actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta ccatgttact
     1861 accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa agtacgatat
     1921 atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt ttcttgttaa
     1981 ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg aattaattat
     2041 gaagtgtaat gaatgtaaca gggttaaata caaccaaatt ttaatttggc tttgcgtttt
     2101 atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg atattgcaaa
     2161 tgattttaat aaaccacctg cgagtacaaa ctgggtgaac acagccttta tgttaacctt
     2221 ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca aaaggttact
     2281 cctatttgga attataataa attgtttcgg gtcggtaatt gggtttgttg gccattcttt
     2341 cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg catttccagc
     2401 actcgtaatg gttgtagttg cgcgctatat tccaaaggaa aataggggta aagcatttgg
     2461 tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg gtggaatgat
     2521 agcccattat attcattggt cctatcttct actcattcct atgataacaa ttatcactgt
     2581 tccgtttctt atgaaattat taaagaaaga agtaaggata aaaggtcatt ttgatatcaa
     2641 aggaattata ctaatgtctg taggcattgt attttttatg ttgtttacaa catcatatag
     2701 catttctttt cttatcgtta gcgtgctgtc attcctgata tttgtaaaac atatcaagaa
     2761 agtaacagat ccttttgttg atcccggatt agggaaaaat atacctttta tgattggagt
     2821 tctttgtggg ggaattatat ttggaacagt agcagggttt gtctctatgg ttccttatat
     2881 gatgaaagat gttcaccagc taagtactgc cgaaatcgga agtgtaatta ttttccctgg
     2941 aacaatgagt gtcattattt tcggctacat tggtgggata cttgttgata gaagaggtcc
     3001 tttatacgtg ttaaacatcg gagttacatt tctttctgtt agctttttaa ctgcttcctt
     3061 tcttttagaa acaacatcat ggttcatgac aattataatc gtatttgttt taggtgggct
     3121 ttcgttcacc aaaacagtta tatcaacaat tgtttcaagt agcttgaaac agcaggaagc
     3181 tggtgctgga atgagtttgc ttaactttac cagcttttta tcagagggaa caggtattgc
     3241 aattgtaggt ggtttattat ccataccctt acttgatcaa aggttgttac ctatggaagt
     3301 tgatcagtca acttatctgt atagtaattt gttattactt ttttcaggaa tcattgtcat
     3361 tagttggctg gttaccttga atgtatataa acattctcaa agggatttct aaatcgttaa
     3421 gggatcaact ttgggagaga gttcaaaatt gatccttttt ttataacagg aattcaaatc
     3481 tttttgttcc attaaagggc gcgattgctg aataaaagat acgagagacc tctcttgtat
     3541 cttttttatt ttgagtggtt ttgtccgtta cactagaaaa ccgaaagaca ataaaaattt
     3601 tattcttgct gagtctggct ttcggtaagc tagacaaaac ggacaaaata aaaattggca
     3661 agggtttaaa ggtggagatt ttttgagtga tcttctcaaa aaatactacc tgtcccttgc
     3721 tgatttttaa acgagcacga gagcaaaacc cccctttgct gaggtggcag agggcaggtt
     3781 tttttgtttc ttttttctcg taaaaaaaag aaaggtctta aaggttttat ggttttggtc
     3841 ggcactgccg acagcctcgc agagcacaca ctttatgaat ataaagtata atgtgttata
     3901 ctttacttgg aagtggttgc cggaaagagc gaaaatgcct cacatttgtg ccacctaaaa
     3961 aggagcgatt
//
LOCUS       DAYNVV010000203         3707 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.guided.132, whole genome shotgun sequence.
ACCESSION   DAYNVV010000203 DAYNVV010000000
VERSION     DAYNVV010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3707
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.guided.132"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            178..1245
                     /gene="rlmN"
                     /locus_tag="ACGXWR_003043"
     CDS             178..1245
                     /gene="rlmN"
                     /locus_tag="ACGXWR_003043"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFK0804489.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            1235..1441
                     /locus_tag="ACGXWR_003044"
     CDS             1235..1441
                     /locus_tag="ACGXWR_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804490.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(1438..2541)
                     /locus_tag="ACGXWR_003045"
     CDS             complement(1438..2541)
                     /locus_tag="ACGXWR_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFK0804491.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            3094..3642
                     /gene="aac(6')"
                     /locus_tag="ACGXWR_003046"
     CDS             3094..3642
                     /gene="aac(6')"
                     /locus_tag="ACGXWR_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFK0804492.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         1215 a          632 c          744 g         1116 t
ORIGIN      
        1 tggtgtcatc caccaacatc aaaaagtata gagccctttt ctaatacggt atgatgtctt
       61 gtctttttag tttttgtgag attaaagttc tattcgattt atttgtgaag tattgcatta
      121 aggaaatgaa tcatgtatag tatgtagcga aactttgaga aaaagaggga aaatactttg
      181 gaaaaacagt ccatttatgg cttgacgaat gaagaattaa tcaattggtt tatagaaaac
      241 ggcgagaaaa aattccgagc tgcccaagtt tgggaatggt tgtatcaaaa acgtgtaagt
      301 aatttcacag aaatgacgaa tctatcgaaa caattgatcg aaaaattatc ggagcatttt
      361 atcatcaatc ctctaaaaca gatggtcgtc caagaagctt cggatggtac agtaaaatat
      421 ttgtttgaac tccctgataa aaacatgatt gagactgtac tgatgagaca agaatatggc
      481 ttgtcagttt gtgtgacgac acaagtagga tgtaatatcg gctgtacgtt ttgtgcaagc
      541 gggctgctca aaaagaaccg tgatctgact gctggagaaa ttgttgcaca gatcatgatg
      601 gtccaacatt attttgatga gcgcaatctt ggcgaacgcg tttcacatgt cgttgtaatg
      661 gggatcggtg agccatttga taattacgac aatgtaatgg actttttgca tatcatcaat
      721 gatgccaaag gattggcaat tggtgctcgg cacattacag tttccactag tggattagca
      781 cacaaaatca aggaattcgc taataacggc ttgcaagtca atctggctat ttccttgcac
      841 gcgccgaata atgaggtgcg aacatcgatc atgcggatca accgaagttt cccaattgag
      901 aaattgatgg aagctgtgga tgagtattta gagaaaacaa accgtcgaat cacgtttgaa
      961 tatatcatgt tgaatcaagt aaatgataga ccagagcatg cgcaacaatt agcagatcta
     1021 ttaaaagata agaaaaaatt agcatatgtc aacttgattc catataatcc agtcagtgaa
     1081 catgatcaat attctcgcag tccaaaagct gatgtattga gattttatga tgtattgaag
     1141 aaaaacggcg taaactgtgt gatacgtaaa gaacatggta cagatattga tgcagcttgc
     1201 ggacaattgc gaagcaagca aatgaaaaaa acagttgcca aataatcgta tcctactcgt
     1261 tttttcaatt accataaaag gagcagtttt cttaattaag gaactgttca acttaaataa
     1321 gagaaaagat tctatagcga aagctataaa gctttttttg acaagaaaaa ccctcatcaa
     1381 gcaaagaaat gtcctcaatt tgatgacagc ctgcttgatg ggggttttag caattattta
     1441 actgattttc ttatatcctt gctggctttc ttgtgtagca tgataagttt ctacgtcaag
     1501 aatggcctgt ttaaattttt ctcgggtgat ttcataaggc acatgtttaa tatcatttgt
     1561 tgccatggct ttatctaaga ttgcttctaa atcggtcgtg acattgagat tcatgtcggt
     1621 taacgatact ggaagttggt tctttttcat aaacacatag attttatcaa acaaatcgaa
     1681 ctgctgatcc atcatcaata aggtcagtac accataactg acagatgctc cgtgaaggta
     1741 tccctccatt ttttctagaa cagtcgtacc gtaatagaat gagtgtgcca tagcagaatt
     1801 atagttattg ttaactaaaa cagaaaccaa tccggtagta acaatgatat ccgaaacgac
     1861 ttgttcaatt gcatatgagg gacgatcgtc ggcactatct ttcaatgctt gcgtaccata
     1921 agtcaagaga cgatcaatgc acatttttcc gatttggatt cctaatctat ccgtgtagcc
     1981 tagatcatcg ccacgagcag aaaaagtaga ttcgacttct ttggataaag catcgccaat
     2041 acctgcccat aagtatttat caggtgcttc ggcaataatt gctgtatcaa tgaaggtgtg
     2101 tacaggtggt tttgaaggaa agaagagtcc gtccattacg ccttcttcgt tatagatgac
     2161 acataccgca gtgacgggcg aacagttcga accaatagtg ggaaaggtga agactggttt
     2221 agctagtttt tcaccaatga cttttacagt atcgcaagca cggccaccac cgactgcaaa
     2281 caggacgtct gctttttgga cactttcatg ctggatcaac tgttcaatat ttccataagt
     2341 tgaattaccc ccgtaccaga gactggcgac aacctctatt tcctgtgtca aagctacttt
     2401 tattttgttt tctgcctttg aaagtgcagt cttccctcca atcagcacta cttttgtccc
     2461 atattctttg acgattccat ttgctttttc atacgcatct gttccaatgg tataatttgg
     2521 taagaaaaca ctttgactca tattcatttc cttctttctt cgttgaaacg ggttaaaatt
     2581 ttaaagagtg atcgatctga ctgcggctgt agatggagta gaggtgaacc taagacagga
     2641 taagtgatga ataaggtggc atgaacacct tgaaatcatc aataagtatc ctaaaaacga
     2701 acaagtacaa aaacattgaa aacgacaata atgaattttt gttcctctta gtatttctac
     2761 cgattccctt tgcttttttg taattatcta aaaattctaa aaattaagat tattatatga
     2821 aaacaggttt tatttgtcaa ttcataattg gtttttttta aagcaaaaga taatctatat
     2881 catgatgaac aaacagagtt ttttcctcca attgatggct ttcctgatct ttcctatttt
     2941 gaataaagtg tttctgtata atttttttat tttataagta agataaataa tgaaagaata
     3001 gagatactga ttggtagcta aagatttttg agcgagaaca tttcgttttt tcaaaaggac
     3061 tgttagaata agcaagaaca agggggaaga cgtatgataa tcagtgaatt tgaccgtaat
     3121 aatccagtat tgaaagatca gctttctgat ttactgagac tgacttggcc ggaagaatat
     3181 ggagacagct cggcagaaga agtagaagaa atgatgaatc cagaacgaat cgcggtagca
     3241 gcggtagacc aagatgagtt agtaggattt attggtgcaa tccctcaata cggtatcaca
     3301 ggttgggaat tgcatccatt agttgtagaa agctcccgac gaaagaacca aataggtact
     3361 cgattagtca attacttaga aaaagaagta gcttccagag gaggaatcac gatttattta
     3421 ggtacggatg atttagacca tggaacaacg ttaagtcaaa cggacctgta tgagcataca
     3481 tttgataaag tggcttccat ccagaacctt cgtgaacatc cgtatgaatt ctatgaaaaa
     3541 ttaggttata aaatcgtagg tgtcttacca aatgcaaatg gctgggacaa accggatatt
     3601 tggatggcaa aaacgattat tcctcgacca aattctcaat aataaaaaga ggttgtgaca
     3661 gaagtaatca gcttcaagaa ataagaagga atttacgaaa attactt
//
LOCUS       DAYNVV010000204         3273 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.guided.134, whole genome shotgun sequence.
ACCESSION   DAYNVV010000204 DAYNVV010000000
VERSION     DAYNVV010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3273
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.guided.134"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            242..1210
                     /locus_tag="ACGXWR_003047"
     CDS             242..1210
                     /locus_tag="ACGXWR_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFK0804493.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1203..2234
                     /gene="vanA"
                     /locus_tag="ACGXWR_003048"
     CDS             1203..2234
                     /gene="vanA"
                     /locus_tag="ACGXWR_003048"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFK0804494.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2240..2848
                     /locus_tag="ACGXWR_003049"
     CDS             2240..2848
                     /locus_tag="ACGXWR_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFK0804495.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          974 a          625 c          794 g          880 t
ORIGIN      
        1 ctggtgtcat ccaccaacat caaaaagtat agagccataa ttttttagga aaatctcaag
       61 gttatcttta ctttttctta ggaaattaac aatttaatat taagaaacgg ctcgttctta
      121 cacggtagac ttaataccgt aagaacgagc cgttttcgtt cttcagagaa agatttgaca
      181 agattaccat tggcatcccc gttttatttg gtgcctttca cagaaagggt tggtcttaat
      241 tatgaataac atcggcatta ctgtttatgg atgtgagcag gatgaggcag atgcattcca
      301 tgctctttcg cctcgctttg gcgttatggc aacgataatt aacgccaacg tgtcggaatc
      361 caacgccaaa tccgcgcctt tcaatcaatg tatcagtgtg ggacataaat cagagatttc
      421 cgcctctatt cttcttgcgc tgaagagagc cggtgtgaaa tatatttcta cccgaagcat
      481 cggctgcaat catatagata caactgctgc taagagaatg ggcatcactg tcgacaatgt
      541 ggcgtactcg ccggatagcg ttgccgatta tactatgatg ctaattctta tggcagtacg
      601 caacgtaaaa tcgattgtgc gctctgtgga aaaacatgat ttcaggttgg acagcgaccg
      661 tggcaaggta ctcagcgaca tgacagttgg tgtggtggga acgggccaga taggcaaagc
      721 ggttattgag cggctgcgag gatttggatg taaagtgttg gcttatagtc gcagccgaag
      781 tatagaggta aactatgtac cgtttgatga gttgctgcaa aatagcgata tcgttacgct
      841 tcatgtgccg ctcaatacgg atacgcacta tattatcagc cacgaacaaa tacagagaat
      901 gaagcaagga gcatttctta tcaatactgg gcgcggtcca cttgtagata cctatgagtt
      961 ggttaaagca ttagaaaacg ggaaactggg cggtgccgca ttggatgtat tggaaggaga
     1021 ggaagagttt ttctactctg attgcaccca aaaaccaatt gataatcaat ttttacttaa
     1081 acttcaaaga atgcctaacg tgataatcac accgcatacg gcctattata ccgagcaagc
     1141 gttgcgtgat accgttgaaa aaaccattaa aaactgtttg gattttgaaa ggagacagga
     1201 gcatgaatag aataaaagtt gcaatactgt ttgggggttg ctcagaggag catgacgtat
     1261 cggtaaaatc tgcaatagag atagccgcta acattaataa agaaaaatac gagccgttat
     1321 acattggaat tacgaaatct ggtgtatgga aaatgtgcga aaaaccttgc gcggaatggg
     1381 aaaacgacaa ttgctattca gctgtactct cgccggataa aaaaatgcac ggattacttg
     1441 ttaaaaagaa ccatgaatat gaaatcaacc atgttgatgt agcattttca gctttgcatg
     1501 gcaagtcagg tgaagatgga tccatacaag gtctgtttga attgtccggt atcccttttg
     1561 taggctgcga tattcaaagc tcagcaattt gtatggacaa atcgttgaca tacatcgttg
     1621 cgaaaaatgc tgggatagct actcccgcct tttgggttat taataaagat gataggccgg
     1681 tggcagctac gtttacctat cctgtttttg ttaagccggc gcgttcaggc tcatccttcg
     1741 gtgtgaaaaa agtcaatagc gcggacgaat tggactacgc aattgaatcg gcaagacaat
     1801 atgacagcaa aatcttaatt gagcaggctg tttcgggctg tgaggtcggt tgtgcggtat
     1861 tgggaaacag tgccgcgtta gctgttggcg aggtggacca aatcaggctg cagtacggaa
     1921 tctttcgtat tcatcaggaa gtcgagccgg aaaaaggctc tgaaaacgca gttataaccg
     1981 ttcccgcaga cctttcagca gaggagcgag gacggataca ggaaacggca aaaaaaatat
     2041 ataaagcgct cggctgtaga ggtctagccc gtgtggatat gtttttacaa gataacggcc
     2101 gcattgtact gaacgaagtc aatactctgc ccggtttcac gtcatacagt cgttatcccc
     2161 gtatgatggc cgctgcaggt attgcacttc ccgaactgat tgaccgcttg atcgtattag
     2221 cgttaaaggg gtgataagca tggaaatagg atttactttt ttagatgaaa tagtacacgg
     2281 tgttcgttgg gacgctaaat atgccacttg ggataatttc accggaaaac cggttgacgg
     2341 ttatgaagta aatcgcattg tagggacata cgagttggct gaatcgcttt tgaaggcaaa
     2401 agaactggct gctacccaag ggtacggatt gcttctatgg gacggttacc gtcctaatcg
     2461 tgctgtaaac tgttttatgc aatgggctgc acagccggaa aataacctga caaaggaaag
     2521 ttattatccc aatattgacc gaactgagat gatttcaaaa ggatacgtgg cttcaaaatc
     2581 aagccatagc cgcggcagtg ccattgatct tacgctttat cgattagaca cgggtgagct
     2641 tgtaccaatg gggagccgat ttgattttat ggatgaacgc tctcatcatg cggcaaatgg
     2701 aatatcatgc aatgaagcgc aaaatcgcag acgtttgcgc tccatcatgg aaaacagtgg
     2761 gtttgaagca tatagcctcg aatggtggca ctatgtatta agagacgaac cataccccaa
     2821 tagctatttt gatttccccg ttaaataaac ttttaaccgt tgcacggaca aactatataa
     2881 gctaactctt tcggcaggaa acccgacgta tgtaactggt tcttagggaa tttatatata
     2941 gtagatagta ttgaagatgt aaggcagagc gatattgcgg tcattatctg cgtgcgctgc
     3001 ggcaagatag cctgataata agactgatcg catagagggg tggtatttca caccgcccat
     3061 tgtcaacagg cagttcagcc tcgttaaatt cagcatgggt atcacttatg aaaattcatc
     3121 tacattggtg ataatagtaa atccagtagg gcgaaataat tgactgtaat ttacggggca
     3181 aaacggcaca atctcaaacg agattgtgcc gtttaagggg aagattctag aaatatttcg
     3241 gctctttgtc aaataggact gatagagtga gat
//
LOCUS       DAYNVV010000205         3095 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.guided.139, whole genome shotgun sequence.
ACCESSION   DAYNVV010000205 DAYNVV010000000
VERSION     DAYNVV010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3095
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.guided.139"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            93..590
                     /gene="dfrG"
                     /locus_tag="ACGXWR_003050"
     CDS             93..590
                     /gene="dfrG"
                     /locus_tag="ACGXWR_003050"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HFK0804496.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(662..2614)
                     /locus_tag="ACGXWR_003051"
     CDS             complement(662..2614)
                     /locus_tag="ACGXWR_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HFK0804497.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2621..2857)
                     /locus_tag="ACGXWR_003052"
     CDS             complement(2621..2857)
                     /locus_tag="ACGXWR_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804498.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
BASE COUNT          940 a          550 c          514 g         1091 t
ORIGIN      
        1 cttattcaac taacgggcag gataatgaga aaaggttttt tgatagaaat aagaaattag
       61 atggtaaatt agttaaaaag gctgtgttat aaatgaaagt ttctttgatt gctgcgatgg
      121 ataagaatag agtgattggc aaagagaatg acattccttg gaggattccc aaggactggg
      181 aatatgttaa aaatactaca aagggacatc cgataatatt aggtaggaag aaccttgaat
      241 caatcggaag agccttacct gacagaagaa atattattct gacgagagat aaggggttta
      301 cctttaatgg ttgtgaaatt gttcattcaa tagaagatgt ttttgagtta tgtaaaaacg
      361 aagaagaaat ttttattttc ggaggagaac agatttataa tttgtttttc ccttatgttg
      421 agaaaatgta catcacaaaa atacatcatg aattcgaagg agatactttt tttccagaag
      481 tgaattatga ggaatggaat gaggtatttg cccaaaaagg gataaagaat gataaaaatc
      541 cgtataacta ctattttcat gtatatgaaa gaaaaaactt attgagttaa cgggtgcgtt
      601 aattgaagaa gaacagtaaa gataaagcac aagagcttgg gattactcca agctcttttt
      661 gtcatttgaa ataaattata tctttccaat caaattgttt atctgtaatc cctaatcttt
      721 gagcaggtgt caaaaccttt ttatccgctg atttaaaagg gcgacaaaag ttgtagtaag
      781 ttcttagaat tgtaatcgca aattgagcat acttcggatt gaagttagcg taaatatagc
      841 tcttcttatc accacgagct gttgttaatg gtctttcaag agatgatata taacgtctta
      901 tctgttgaat aaagctattg gtcgaatggt cattaacatt taatagcatc tttgcgattt
      961 cgtttggttc cagagcagat aaatccgttc tacaatcaac tgaataaaat cctttatcct
     1021 tagtggctaa tggatgtttg atagggttat cggcatattt gcgatatctt tctccatctt
     1081 tactaatagc ctcttcgtgg aattgatgac ttgttagtaa ttcagttaga taatgagatg
     1141 ccaaagtccg tagaaacttt gttttgaatc ctctgatatc tccccaatcg agcagttctg
     1201 cttttgcttg tccgaattct tttaagcatt gttttctgct tttcgtcttg ttaacttggc
     1261 aaataaaatg atgtgcatcg ctcaacctta attctttcgt gaatactcta taaaaggcgt
     1321 ttctaataga gaagtcatca tcactaatca ttcgccattc gtcggcatta accatttgtt
     1381 taattaacca atagtgagca gttgtagtat aaggagcatc aacatttaaa ccatcgacaa
     1441 atctactcct attagtaatt ttccctaatt cgtgaagata agcattccta ttttcgctat
     1501 cgttagcgga tggttcttgt ggataataag accaatctaa cctatcattt ttacgactaa
     1561 aagtattgag atggtcttct ttgaattttc ttgtatcttc atttaattca tccattgaaa
     1621 tattccaatc ataggcaaca tcagaacgga acacatatct tgataagacc tcagcagata
     1681 caactatata cgtttgcata ttaaggtctt caaaccccgt atatttcttt gaaccttgtc
     1741 ctttcttacg gacgttattt aggtagtagt gcatcttgtc cgtattaagc cacatctcgt
     1801 taaatttctt tgtttgaagg ggttgtgtct catatcgttc taaaaactcc aaacaacgcc
     1861 tatacagcca ctccagctta tgatagtagg ttccaactcc aattcctaaa atatcacaag
     1921 tacgactgac tgaaaccctt ccaacaacca tcttagcgaa cattggaaga atggtgttct
     1981 tttgttggtg ataagtagtg gtttcttctc tttttggtag aacattagtg aacttcttac
     2041 acgccttaca ttgatagcgt tgagatttgc ccctactttt cccccttttg taaaattgct
     2101 tcggctcatt gaatggggtt gattcttctt ccgagcagcc ttctttatga aattgataat
     2161 ctggctcaac atcttggatg ctattgattt ctataaggcg tttaatttct tcaacaacag
     2221 accaattaga taaaggggtt actgtacagt tttgcgatac acctctgcca ataggattgt
     2281 cattgcagta cataccttta tgacctttat ctttggaact accagtcatt ttatatcgac
     2341 ttggtttccc ttttacatct ttgaatttgt gctgttcttt cccaaaatta caacaaaacg
     2401 gattgatgca gtaattatat tgaatgggat attcagaacc gttccattta aaagacgttg
     2461 gcaagaacaa cattttgtta taccttgttg caaatcgttt tggagttaat aaatcatatt
     2521 gtttagccct atcttttaat tcttcgtttg aaatcggaat tttaacatct acaatttcat
     2581 cttccttcgt ggctaatctt ttaagcttgg tcattgtcta tcaacccact ctatctttga
     2641 tacccatttt ttcaacaatc cgcttattac ttcgcttgtt ggcaatccat tcaataaact
     2701 tcttatcgtc taaaatgttc aataagaatt catccactgc ttcgctttca gtacgctctg
     2761 catattcagc gtattgctta actatcaccc ttacttgctc tgatatttcc caatccacag
     2821 acttagcgtt cttatttttt ggctcaagaa attgcatagg aaaatgcacc cctttttgct
     2881 tagtaaattg taaccatttt aacacaccaa tttgcattcc tacaataatt atttcacgtt
     2941 cgcattttta tatacatttt aacttacatt ttgtggtgta aattaacaac aaacgttgat
     3001 ttaacaataa aaaacgagta tcaaattcag ttgcaatttg atactcattt aggtttacat
     3061 tttcactttt tgtactccaa aactgaacta cttaa
//
LOCUS       DAYNVV010000206         2516 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.guided.145, whole genome shotgun sequence.
ACCESSION   DAYNVV010000206 DAYNVV010000000
VERSION     DAYNVV010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2516
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.guided.145"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..423
                     /locus_tag="ACGXWR_003053"
     CDS             <1..423
                     /locus_tag="ACGXWR_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFK0804499.1"
                     /translation="PYLIVDLKLCNRTTRITRSTQDLFELIDNIRDKKASLKSLKDTW
                     LDLSEDNPYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAG
                     MNYAVKLYKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            637..1332
                     /gene="vanR-A"
                     /locus_tag="ACGXWR_003054"
     CDS             637..1332
                     /gene="vanR-A"
                     /locus_tag="ACGXWR_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFK0804500.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1310..2464
                     /locus_tag="ACGXWR_003055"
     CDS             1310..2464
                     /locus_tag="ACGXWR_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="HFK0804501.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          866 a          449 c          529 g          672 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaacca ctcgaatcac tcgtagtaca
       61 caagatctat ttgaattaat cgataacata cgagataaaa aggcaagttt aaaatcacta
      121 aaagatacat ggcttgattt atcagaagat aatccataca gccaattctt aattactgta
      181 atggctggtg ttaaccaatt agagcgagat cttattcgga tgagacaacg tgaagggatt
      241 gaattggcta agaaagaagg aaagtttaaa ggtcgattaa agaagtatca taaaaatcac
      301 gcaggaatga attatgcggt aaagctatat aaagaaggaa atatgactgt aaatcaaatt
      361 tgtgaaatta ctaatgtatc tagggcttca ttatacagga aattatcaga agtgaataat
      421 tagccattct gtattccgct aatgggcaat atttttaaag aagaaaagga aactataaaa
      481 tattaacagc ctcctagcga tgccgaaaag ccctttgata aaaaaagaat catcatctta
      541 agaaattctt agtcatttat tatgtaaatg cttataaatt cggccctata atctgataaa
      601 ttattaaggg caaacttatg tgaaagggtg ataactatga gcgataaaat acttattgtg
      661 gatgatgaac atgaaattgc cgatttggtt gaattatact taaaaaacga gaattatacg
      721 gttttcaaat actataccgc caaagaagca ttggaatgta tagacaagtc tgagattgac
      781 cttgccatat tggacatcat gcttcccggc acaagcggcc ttactatctg tcaaaaaata
      841 agggacaagc acacctatcc gattatcatg ctgaccggga aagatacaga ggtagataaa
      901 attacagggt taacaatcgg cgcggatgat tatataacga agccctttcg cccactggag
      961 ttaattgctc gggtaaaggc ccagttgcgc cgatacaaaa aattcagtgg agtaaaggag
     1021 cagaacgaaa atgttatcgt ccactccggc cttgtcatta atgttaacac ccatgagtgt
     1081 tatctgaacg agaagcagtt atcccttact cccaccgagt tttcaatact gcgaatcctc
     1141 tgtgaaaaca aggggaatgt ggttagctcc gagctgctat ttcatgagat atggggcgac
     1201 gaatatttca gcaagagcaa caacaccatc accgtgcata tccggcattt gcgcgaaaaa
     1261 atgaacgaca ccattgataa tccgaaatat ataaaaacgg tatggggggt tggttataaa
     1321 attgaaaaat aaaaaaaacg actattccaa actagaacga aaactttaca tgtatatcgt
     1381 tgcaattgtt gtggtagcaa ttgtattcgt gttgtatatt cgttcaatga tccgagggaa
     1441 acttggggat tggatcttaa gtattttgga aaacaaatat gacttaaatc acctggacgc
     1501 gatgaaatta tatcaatatt ccatacggaa caatatagat atctttattt atgtggcgat
     1561 tgtcattagt attcttattc tatgtcgcgt catgctttca aaattcgcaa aatactttga
     1621 cgagataaat accggcattg atgtacttat tcagaacgaa gataaacaaa ttgagctttc
     1681 tgcggaaatg gatgttatgg aacaaaagct caacacatta aaacggactc tggaaaagcg
     1741 agagcaggat gcaaagctgg ccgaacaaag aaaaaatgac gttgttatgt acttggcgca
     1801 cgatattaaa acgcccctta catccattat cggttatttg agcctgcttg acgaggctcc
     1861 agacatgccg gtagatcaaa aggcaaagta tgtgcatatc acgttggaca aagcgtatcg
     1921 actcgaacag ctaatcgacg agttttttga gattacacgg tataacctac aaacgataac
     1981 gctaacaaaa acgcacatag acctatacta tatgctggtg cagatgaccg atgaatttta
     2041 tcctcagctt tccgcacatg gaaaacaggc ggttattcac gcccccgagg atctgaccgt
     2101 gtccggcgac cctgataaac tcgcgagagt ctttaacaac attttgaaaa acgccgctgc
     2161 atacagtgag gataacagca tcattgacat taccgcgggc ctctccgggg atgtggtgtc
     2221 aatcgaattc aagaacactg gaagcatccc aaaagataag ctagctgcca tatttgaaaa
     2281 gttctatagg ctggacaatg ctcgttcttc cgatacgggt ggcgcgggac ttggattggc
     2341 gattgcaaaa gaaattattg ttcagcatgg agggcagatt tacgcggaaa gcaatgataa
     2401 ctatacgacg tttagggtag agcttccagc gatgccagac ttggttgata aaaggaggtc
     2461 ctaagagatg tatataattt tggctctttg tcaaatgatg ttggtaaaga gaaatc
//
LOCUS       DAYNVV010000207         1548 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.guided.157, whole genome shotgun sequence.
ACCESSION   DAYNVV010000207 DAYNVV010000000
VERSION     DAYNVV010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.guided.157"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(39..341)
                     /locus_tag="ACGXWR_003056"
                     /pseudo
     CDS             complement(39..341)
                     /locus_tag="ACGXWR_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
     gene            434..783
                     /locus_tag="ACGXWR_003057"
                     /pseudo
     CDS             434..783
                     /locus_tag="ACGXWR_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1055..1345)
                     /locus_tag="ACGXWR_003058"
     CDS             complement(1055..1345)
                     /locus_tag="ACGXWR_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFK0804502.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT          499 a          297 c          216 g          536 t
ORIGIN      
        1 atggattttt tcatttacac aaaatatttt atactctcaa catacttgca aagtaatact
       61 acaattccta acataatcgt agaatttaat aatttccata gcataaagtg tttagaaaag
      121 aacattaaga atagttctat aataattctt gaactccatg tcttataatg ttctatcgaa
      181 gcacccaaat agccaagttc atctaatcta cttgcataaa ctacgtcatc cgctctcata
      241 gtcggcatat acatattaaa gagtaaaaag ataccccaaa tccctattag taacaagatc
      301 agttctttgt tattcgttat ttttctatta tgtttgttca tttttatact ccttcttata
      361 tttcctaata gagtataaca tagctttaag cattacttaa agataactta aaagttatct
      421 tttaaatact taattgttaa ataccttatt tgatgcaaaa gaaatctacg atagtcaaca
      481 aaaaaatttt cattatatcc agaaaaattt ttcttagtta aggacctatg gattgcagta
      541 atgcagaatt cgtcgaataa actgccaaag acatacaatc atattgcttt taaaattgac
      601 gaacaagata tagattcgtt tgtctcaaaa atccaaatgt taggtttaac tgtcgaacca
      661 ggacgttctc gtgtgaaagg cgaggcttct tcaatttact tttacgacta tgataatcac
      721 ctcttcgagt tacataccgg tactctccag gaacgtttaa aatcctacaa ttccactacc
      781 tgagactagt aatgactagt ctctttttat ggcctctgat ccccccattg agcgaatact
      841 aatagggctt cgaattgatc tgttcaatct ttaagcaata tccctcaaat gagtttggaa
      901 agtttagtga ttcatcacaa atacttaaat acatgtagtt atatatagat tgaggttctt
      961 gtgagcgtat gctcgtgtgg gttcaaatcc catcgtctgc atccatcttt ccaaaacaag
     1021 cggctaggac atttttgtct cagccgcttg ttttctagtt tattctttca tcttgtcgga
     1081 ccttttttct tgggtataga cttttctcat attctaccac aattttgggt ttccctaaca
     1141 catgatagga tctcacaaca aattgctttc tattattata ataacctgta acgactaact
     1201 tcatcccttc gtctacttca gctaggaagt tcaaactatg ggaagcaatc aaacaattga
     1261 ccccatttaa actgaaacgg atcaacggtc tggcactaac ttgcaaagta cggatcttat
     1321 ctactgttcc atattttttc tccataacct tcacctcaat accattatac gaacatacat
     1381 tccctttgta aagaagaaac tctgttttat ctttttgact ttttgtctat tacctttctt
     1441 aaaatcatat tggcacttcc tgcgaagatg aaggacatgt actaaaaaaa agaggcagca
     1501 gtatagattt aagtagttca gttttggagt acaaaaagtg aaaatgta
//
LOCUS       DAYNVV010000208         1136 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.guided.176, whole genome shotgun sequence.
ACCESSION   DAYNVV010000208 DAYNVV010000000
VERSION     DAYNVV010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.guided.176"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..1120
                     /locus_tag="ACGXWR_003059"
                     /note="aph(2'')-Ia"
     CDS             <1..1120
                     /locus_tag="ACGXWR_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HFK0804503.1"
                     /translation="GFYSLFKTLQQNRTRYIKLIFEFLKKERNANAVILDPHKNNPRA
                     IRAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKV
                     DSIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNI
                     EYSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDIS
                     ECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFS
                     CNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDI
                     EKAKEYQDIVEEYYPIETIVYGIKNIKQEFIESVKYFV"
BASE COUNT          477 a           91 c          188 g          380 t
ORIGIN      
        1 gggattttat tctttattta aaactttgca acagaaccgt acaagatata ttaaattgat
       61 ttttgaattt ttgaaaaaag aaagaaatgc taatgcagtt attttagacc ctcataaaaa
      121 taatccaaga gcaataaggg cataccaaaa atctggtttt agaattattg aagatttgcc
      181 agaacatgaa ttacacgagg gcaaaaaaga agattgttat ttaatggaat atagatatga
      241 tgataatgcc acaaatgtta aggcaatgaa atatttaatt gagcattact ttgataattt
      301 caaagtagat agtattgaaa taatcggtag tggttatgat agtgtggcat atttagttaa
      361 taatgaatac atttttaaaa caaaatttag tactaataag aaaaaaggtt atgcaaaaga
      421 aaaagcaata tataattttt taaatacaaa tttagaaact aatgtaaaaa ttcctaatat
      481 tgaatattcg tatattagtg atgaattatc tatactaggt tataaagaaa ttaaaggaac
      541 ttttttaaca ccagaaattt attctactat gtcagaagaa gaacaaaatt tgttaaaacg
      601 agatattgcc agttttttaa gacaaatgca cggtttagat tatacagata ttagtgaatg
      661 tactattgat aataaacaaa atgtattaga agagtatata ttgttgcgtg aaactattta
      721 taatgattta actgatatag aaaaagatta tatagaaagt tttatggaaa gactaaatgc
      781 aacaacagtt tttgagggta aaaagtgttt atgccataat gattttagtt gtaatcatct
      841 attgttagat ggcaataata gattaactgg aataattgat tttggagatt ctggaattat
      901 agatgaatat tgtgatttta tatacttact tgaagatagt gaagaagaaa taggaacaaa
      961 ttttggagaa gatatattaa gaatgtatgg aaatatagat attgagaaag caaaagaata
     1021 tcaagatata gttgaagaat attatcctat tgaaactatt gtttatggaa ttaaaaatat
     1081 taaacaggaa tttatcgaga gtgtaaaata ttttgtgtaa atgaaaaaat ccatac
//
LOCUS       DAYNVV010000209          981 bp    DNA     linear   BCT 16-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37260
            SAMN42839134-rid22427263.guided.182, whole genome shotgun sequence.
ACCESSION   DAYNVV010000209 DAYNVV010000000
VERSION     DAYNVV010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN42839134
            Sequence Read Archive: SRR30007213
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 26-JUL-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002267972.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002267972.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/16/2024 11:17:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,061
            CDSs (total)                      :: 2,990
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 50 of 109
            Pseudo Genes (incomplete)         :: 56 of 109
            Pseudo Genes (internal stop)      :: 32 of 109
            Pseudo Genes (multiple problems)  :: 23 of 109
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..981
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN42839134-rid22427263.guided.182"
                     /strain="VRE37260"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2021"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            87..146
                     /gene="ermCL"
                     /locus_tag="ACGXWR_003060"
     CDS             87..146
                     /gene="ermCL"
                     /locus_tag="ACGXWR_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002497446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methylase leader peptide ErmCL"
                     /protein_id="HFK0804504.1"
                     /translation="MGIFSIFVINTVHYQPNKK"
     gene            206..940
                     /locus_tag="ACGXWR_003061"
     CDS             206..940
                     /locus_tag="ACGXWR_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011282421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(T)"
                     /protein_id="HFK0804505.1"
                     /translation="MNKKNIKDSQNFITSKHHINEILRNVHLNTNDNIIEIGSGKGHF
                     TFELAKRCNYVTAIEIDPKLCRITKNKLIEYENFQVINKDILQFKFPKNKSYKIYGNI
                     PYNISTDIIRKIVFESTATESYLIVEYGFAKRLLNTNRSLALFLMTEVDISILSKIPR
                     EYFHPKPRVNSSLIVLKRHPSKISLKDRKQYENFVMKWVNKEYIKLFSKNQFYQALKY
                     ARIDDLNNISFEQFLSLFNSYKLFNR"
BASE COUNT          404 a          120 c          133 g          324 t
ORIGIN      
        1 agggatttta ttctttattt aaaactttgc aacagaacca gcttgtgcta taattattct
       61 aatttcataa aaaggagaat taatatatgg gcatttttag tatttttgta atcaacacag
      121 ttcattatca accaaacaaa aaataagtgg ttataatgga ttgttaatat aaacattcat
      181 tataacctca taggagtggg ttataatgaa caaaaaaaat ataaaagata gtcaaaactt
      241 tattacttca aagcatcata taaatgaaat tttgagaaat gtacatttaa atacaaatga
      301 taatattatt gagattggtt cagggaaagg tcatttcacg tttgaattag ctaaaaggtg
      361 taattatgta accgccattg aaatagatcc taaattatgt aggataacta aaaacaaact
      421 tattgaatat gagaacttcc aggttatcaa taaagatatt ttacaattta agtttcctaa
      481 aaataagtca tataagatat atggaaatat accctacaat ataagtacag atataattcg
      541 aaaaattgtt tttgaaagca cagctacaga aagttattta atagtggaat atggatttgc
      601 taaaaggttg ctaaatacaa atcgttcact agcactattt ttaatgacag aagttgatat
      661 atccatatta agtaaaatcc ctagagaata ctttcatcca aaacctagag ttaatagctc
      721 gttaattgta ttaaaaagac acccttcaaa aatatcactc aaagatagaa aacaatatga
      781 aaattttgtt atgaaatggg ttaacaaaga atacataaaa ctattttcca aaaaccaatt
      841 ttatcaagcc ttaaaatatg caagaattga cgatttaaac aatattagct ttgaacaatt
      901 cttgtctctt ttcaatagct ataaattatt taatagataa gttaggctct ttgtcaaatg
      961 atgttggtaa agagaaatct t
//
